diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c6a0fe55354d2e04b9c0ff21ae667b0349efbc44 --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Serine/threonine-protein kinase, active site [IPR008271]", "1": "Ubiquitin-conjugating enzyme, active site [IPR023313]"} \ No newline at end of file diff --git a/interpro_active_site/basic/plot_0.png b/interpro_active_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..648637c2a8c5af9b31a5a4dd585e7a446932af13 --- /dev/null +++ b/interpro_active_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:33bea139c2cd17d60958295c0e19780d26f6e527e2eb809e18bd2749c16ff348 +size 156397 diff --git a/interpro_active_site/basic/plot_1.png b/interpro_active_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..4362baa7925019ab1839730fd5905f276d26f0e8 --- /dev/null +++ b/interpro_active_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d843ba961fc98fd4b1cc4d3a9b5c13e829233a3ed3b299f44ed0afc14e62b36c +size 151194 diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..ed0ff9765090c5b7db42636704258c5ea8bf342d --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9ea3a9a17e3bcf2a17270489ac209b0b58ceab10b58bb61331f93ca0e04f4eed +size 86836 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4ab08f1a01ac0cde1b3a48f629ededd4b28bb636 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 57, + "title": "Average number of proteins per term", + "value": 2.789473684210526 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5259484f600e61d4f0879f41caed4bce7b50bfa8 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a8078e2ff4548f86b81c80ac686166c60fb1b078 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,11 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.7488282326991985 0.9429077023470646 0.3457281148418578 0.9999999999685064 0.5185921722627868 3 Q9UBT2,P22314 2 +Thiolase, active site [IPR020610] 0.5054852318969566 0.6080018282469704 0.5431862613355052 1.0 0.7006583390635989 5 P24752,P42765,P55084 3 +Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999] 0.6117088983662013 0.4615336101527307 0.644415813536587 1.0 0.7985152472083795 3 Q16881 1 +ATP:guanido phosphotransferase active site [IPR022415] 0.5722160970231421 0.3789948062627716 0.7046917206616017 1.0 0.8546261293130063 2 P12532 1 +Thiolase, acyl-enzyme intermediate active site [IPR020615] 0.4127557511531085 0.2753231721784923 0.78306796332388 1.0 0.9109157940706358 5 P24752,P42765,P55084 3 +Malate dehydrogenase, active site [IPR001252] 0.4385336273428749 0.0859296889292064 0.931522310438931 1.0 0.9873195015211924 2 P40925 1 +Ribonucleotide reductase small subunit, acitve site [IPR030475] 0.41179713340682 0.0571188673864634 0.9544505069578142 1.0 0.9873195015211924 2 Q7LG56 1 +Serine/threonine-protein kinase, active site [IPR008271] 0.1968286886207173 0.0451156924892723 0.964015093360798 1.0 0.9873195015211924 57 Q13464,P51956,O00311,Q2M2I8,Q9H2G2,Q9Y5S2 6 +Peptidase S16, active site [IPR008268] 0.3864388092612875 0.0376106621673859 0.9699981067576626 1.0 0.9873195015211924 2 P36776 1 +Ubiquitin-conjugating enzyme, active site [IPR023313] 0.2284768211920498 0.0067415034217495 0.9946210992464796 1.0 0.9946210992464796 6 P61086,P68036,Q16763,P61088,P60604 5 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6936a6daddd99375168b57ef8e678b6142efced9 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA/RNA non-specific endonuclease, active site [IPR018524]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPN5", "CDC42BPB", "CDC7", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "ENDOG", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "LONP2", "MAP2K1", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "NCEH1", "NEK3", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "VRK2", "WNK1"], "leading_proteins": ["AAK1", "ACAA2", "ACAT1", "CDC42BPB", "CDC7", "CKMT1A*", "HADHB", "LONP1", "MDH1", "NEK3", "ROCK1", "RRM2B", "SLK", "TXNRD1", "UBA1", "UBA2", "UBE2G2", "UBE2K", "UBE2L3", "UBE2N", "UBE2S"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6cc103c3aeab8f869136acd9de59a2c0271afc60 --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "IQ motif, EF-hand binding site [IPR000048]"} \ No newline at end of file diff --git a/interpro_binding_site/advanced/plot_0.png b/interpro_binding_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ea5928685eb1ed5d11913de5d50a70c805148b62 --- /dev/null +++ b/interpro_binding_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:08c52841f7de8da97c4667fbdc9a0b159a45d7ed8e63ee3a17adc41aeb752604 +size 184684 diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7a67b7ee56098949aa21f34dc10a407e1f90753f --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "IQ motif, EF-hand binding site [IPR000048]", "1": "Protein kinase, ATP binding site [IPR017441]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f7ee80434f800cecbe8cc3cbc5c00902b15b266b --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e856815d4b40166c0bfbe503502d72a835730c18773c706cf129303413d5fbc4 +size 141047 diff --git a/interpro_binding_site/basic/plot_1.png b/interpro_binding_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b4408589ea719cd3e3373c75be7d4b936cc9041c --- /dev/null +++ b/interpro_binding_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ae57ed05b4e7ebdae80e814b0fc587a8068433ca0a80908f19b59806ef28a7b2 +size 155843 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..36c66a975a1e7149f124ddeddb66f4f7248189ab --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9956328e56c887fc447441b93409bbe633bfd3b141b4062e449e6de70d09ce3d +size 83114 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9847b18a2c6ff13fb72f6ee49de8dd75b96fe565 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +IQ motif, EF-hand binding site [IPR000048] 9 12 2.6203436625621785 0.0087841196022806 4.902912621359223 10.79368932038835 -0.2273048691062784 0.5134620963427197 2.787853554074696 2.339749173467172 1.002129759133213 0.3214407723554939 1.0 0.1788224008957527 0.0583817580096799 0.0161470643842222 0.0028781147210985 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d914d8f0bc7766f46ae13010112224f0d7de5cfb --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 4.818181818181818 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7f49b42480d3c9de866a684bdcdfbfe4af4dba78 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d71cefc2254d1c1e6504e756de43ba61cd0efc1e --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +IQ motif, EF-hand binding site [IPR000048] 0.7023786711577714 2.6203436625621785 0.0087841196022806 0.252601377148282 0.0598252310652483 12 Q15051,Q92614,Q86VI3,Q7Z406,P35580,O00159,P35579,O94832,O43795 9 +PPM-type phosphatase, divalent cation binding [IPR000222] 0.6441700337790095 1.0011911144917234 0.3167344214866063 0.9999965209962236 0.5406841854550489 4 Q9P0J1 1 +Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838] 0.6105292171995493 0.5045445617652295 0.61387875606005 0.999999999999977 0.8440832895825688 2 P00505 1 +2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016] 0.4484280198565903 0.2797323317268093 0.7796828710492696 1.0 0.8865483339202777 4 P36957,P10515,P11182 3 +Aconitase family, 4Fe-4S cluster binding site [IPR018136] 0.5361080485115709 0.2756989823638686 0.7827792773058038 1.0 0.8865483339202777 2 Q99798 1 +Protein kinase, ATP binding site [IPR017441] 0.2278827345769233 0.2456501932920296 0.8059530308366161 1.0 0.8865483339202777 51 Q13464,Q16513,P51956,O00311,O96013,O95747,Q13043,Q99640,Q9H2G2,O75116,P11802,Q9Y5S2 12 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b6b1ed2a49f3b2245355e3cb527e6f25e49d6971 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit I, copper-binding site [IPR023615]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "APOBEC3C", "ARG2", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDC7", "CDK1", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX1", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "MCFD2", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NEK3", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PDP1", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK26", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["ACO2", "CDC42BPB", "CDC7", "CDK4", "DBT", "DLAT", "DLST", "GOT2", "IQCB1", "IQGAP3", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NEK3", "OXSR1", "PAK4", "PDP1", "PKMYT1", "PKN2", "ROCK1", "ROCK2", "SLK", "STK4"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..22ae5a793d098239640605850e546e04e92f3b4b --- /dev/null +++ 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RING-type, conserved site [IPR017907]", "3": "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "4": "Heat shock protein 70, conserved site [IPR018181]", "5": "Actinin-type actin-binding domain, conserved site [IPR001589]", "6": "DnaJ domain, conserved site [IPR018253]", "7": "Kinesin motor domain, conserved site [IPR019821]", "8": "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "9": "Chaperonin TCP-1, conserved site [IPR002194]", "10": "ATPase, AAA-type, conserved site [IPR003960]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a6ff03b60ffdd15c52d97ada2e7ee97e8190d665 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6757c7cbf548eb74b32743c1352640c6befae9dcccbb632c826aa6477e411369 +size 138407 diff --git 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0000000000000000000000000000000000000000..503e21af90be1241d6d95120dcc9ef912f129409 --- /dev/null +++ b/interpro_conserved_site/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:96979b8c3806a066cb95e3e4a7c6a46837e2ef3cde1e8114d896a0cd399699d2 +size 140841 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8927e1b510b6bcb77656c3900f782b9ec5d6d132 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ac852d1fc85712678cad282ae3052df5627ce603024f9381ac37fc3eea10e853 +size 112724 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e4c3514372df13b71cb3a31b1e4f61ffe73f01cc --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Bromodomain, conserved site [IPR018359] 7 11 2.3942940369652987 0.0166523930788984 5.529126213592233 9.820388349514564 -0.8552206791946717 0.3841686679671253 2.4920507041843005 1.8359336252623952 0.9945124236501974 0.3161254538359859 1.0 0.1157751708195439 0.2186221342412543 0.4627901258069825 0.1199524552735497 +Intermediate filament protein, conserved site [IPR018039] 3 8 2.2063478693322987 0.0273596520935615 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 1.0 1.0 0.1626892876910785 0.0708153438700075 0.0098879726868235 +Zinc finger, PHD-type, conserved site [IPR019786] 8 18 2.194114363751661 0.0282271889017433 7.924757281553398 15.968446601941748 -0.8932990755852599 0.405709433078066 4.135058338809696 3.50470897017074 1.057968995875309 0.3390198533771147 1.0 1.0 0.1043706933170995 0.4007853524207055 0.0539791573859534 +Zinc finger, RING-type, conserved site [IPR017907] 8 17 2.129306995722241 0.0332288693923552 4.609223300970874 14.776699029126211 -0.045326225777209 0.5577732895844865 3.238903742779499 4.550007017672923 0.8841385018499901 0.2924846286854669 1.0 0.0876325329480415 0.0767446240128207 0.4522434981148837 0.7323442203982553 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892] 5 13 2.082366322184312 0.0373090221723495 4.951456310679611 9.776699029126211 -0.8483999101163021 0.4005956075506935 2.187247420210493 1.8164942167575489 0.9035429813719144 0.3144938579483745 1.0 1.0 1.0 0.0064387619157215 0.0063533232968262 +Heat shock protein 70, conserved site [IPR018181] 6 10 2.04187738612514 0.0411636954671221 5.157766990291262 9.618932038834952 -0.5977526314899951 0.5182608346902362 2.6978709448427782 0.6407904897015557 0.7298098612304945 0.3042104761407978 1.0 1.0 1.0 0.2577455317022596 0.113339965404402 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..869042d9b9dcb1b4362ca3dc7c0ef7970ccf58d6 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 290, + "title": "Average number of proteins per term", + "value": 2.8241379310344827 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c9f3fae2c19a17330402dcaf0ea873d78200570a --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..59d6bf08f38cbf48c34e003a913c3338636b5fa6 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,59 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Bromodomain, conserved site [IPR018359] 0.6788587103071793 2.3942940369652987 0.0166523930788984 0.9923255207926898 0.1097544089291032 11 Q86U86,O60885,Q15059,Q12830,Q9NRL2,P25440,Q9UIG0 7 +Intermediate filament protein, conserved site [IPR018039] 0.703155027164301 2.2063478693322987 0.0273596520935615 0.9996792537397 0.1469314649469043 8 Q03252,P07197,P48681 3 +Zinc finger, PHD-type, conserved site [IPR019786] 0.5469739815948695 2.194114363751661 0.0282271889017433 0.9997523856917572 0.1488342687546468 18 Q96T23,Q9UIG0,Q12830,Q9Y2K7,Q92576,O94880,Q9BTC0,Q96L73 8 +Zinc finger, RING-type, conserved site [IPR017907] 0.5456203145342507 2.1293069957222412 0.0332288693923552 0.9999445546383492 0.1690591600663688 17 Q14527,O60858,Q99496,O75150,P14373,Q13049,O15344,Q99590 8 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892] 0.5924653288973027 2.0823663221843116 0.0373090221723495 0.9999837369688608 0.1717399433330376 13 Q9Y3C6,Q13356,P30414,Q13427,Q6UX04 5 +Heat shock protein 70, conserved site [IPR018181] 0.6310757041328163 2.0418773861251394 0.0411636954671221 0.9999949196207824 0.1865229950853973 10 P34932,P0DMV9,O95757,P54652,P11142,Q9Y4L1 6 +Actinin-type actin-binding domain, conserved site [IPR001589] 0.5450998586539562 1.8997772895150435 0.0574623524761221 0.999999964793344 0.2109377495958916 14 Q14315,O75369,Q01082,P21333,P46939 5 +DnaJ domain, conserved site [IPR018253] 0.5493048551630404 1.8062343960157996 0.0708817343400969 0.9999999994497129 0.2335875336207739 13 Q5F1R6,Q8WXX5,O75190,Q99543,Q96EY1,P25685,Q9NXW2 7 +FERM conserved site [IPR019747] 0.6258731938875406 1.7930097298110963 0.07297136830346 0.9999999997135738 0.2377718742472294 8 Q9Y2J2,O43491,Q9Y490 3 +Ribosomal protein L7Ae conserved site [IPR004037] 0.8993936052921853 1.6802568705745655 0.0929073486053986 0.9999999999994764 0.2777642380986144 2 P62424 1 +Kinesin motor domain, conserved site [IPR019821] 0.5177210386375443 1.600688128733997 0.1094460117906153 0.9999999999999974 0.308148965235713 13 Q99661,Q02241,Q9Y496,Q14807,Q86Y91,Q96Q89,O00139,P33176 8 +Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.7275148223035852 1.5886576497296985 0.1121377051227752 0.999999999999999 0.3097136617676648 5 P48735 1 +Adenylate kinase, conserved site [IPR033690] 0.7259090751719876 1.5814618300886831 0.1137724797837465 0.9999999999999992 0.3112643314838347 5 P27144,Q9UIJ7 2 +Ribosomal protein L24e, conserved site [IPR023442] 0.8539140022050822 1.487196419244592 0.1369629415228848 1.0 0.3413127732417349 2 Q9UHA3 1 +Guanylate kinase, conserved site [IPR020590] 0.591836842002158 1.3955894181089306 0.1628381708251307 1.0 0.3660703065061079 7 Q8N3R9 1 +Ribosomal S11, conserved site [IPR018102] 0.7965821389195332 1.243616951273579 0.2136405743789753 1.0 0.4363082152810059 2 P82912 1 +Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.7910694597574397 1.2202845690283952 0.2223570173962055 1.0 0.4380596422137154 2 Q9UBT2 1 +Mini-chromosome maintenance, conserved site [IPR018525] 0.5862873484644919 1.1855887615813745 0.2357847425991412 1.0 0.4502377006457545 6 P33991 1 +Ribosomal protein L24/L26, conserved site [IPR005825] 0.7690187431091748 1.1272908470243848 0.2596195309950788 1.0 0.4697413659573012 2 P61254 1 +Chromo domain, conserved site [IPR023779] 0.6130484839376409 1.0729077196873664 0.283312522076093 1.0 0.494943562663054 5 P45973,O14646,Q13185 3 +Vinculin, conserved site [IPR000633] 0.7475192943770839 1.0373364048599618 0.2995791051352816 1.0 0.5202271885582734 2 P18206 1 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.7683876154021982 1.017215074089716 0.3090511265806719 1.0 0.5303244183928689 3 P26583 1 +Enolase, conserved site [IPR020809] 0.7392502756339656 1.0029873948620576 0.3158669431358314 1.0 0.5388318441728889 2 P09104 1 +Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867] 0.7086549062844847 0.8774972371609495 0.3802166188448967 1.0 0.605839667390346 2 P13995 1 +Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628] 0.7086549062844487 0.877497237160804 0.3802166188449758 1.0 0.605839667390346 2 Q6UB35 1 +Ubiquitin specific protease, conserved site [IPR018200] 0.3750883376559872 0.8518544614743688 0.3942948744832553 1.0 0.6143111881456154 16 P40818,Q9UPT9 2 +Ubiquitin interacting motif [IPR003903] 0.5577950991264691 0.8283879103890154 0.4074508509890702 1.0 0.6143111881456154 5 O14964 1 +AT hook, DNA-binding motif [IPR017956] 0.7179487179487157 0.8274655486570826 0.4079732411701902 1.0 0.6143111881456154 3 P17096,Q6ZRS2 2 +Ribosomal protein L13, conserved site [IPR023563] 0.6948732083792666 0.8219971075503235 0.4110785431085282 1.0 0.6143111881456154 2 P40429 1 +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.5963237541118293 0.8041725570795594 0.4212973254774659 1.0 0.6201838801444929 4 Q8N4Q0 1 +Sterol reductase, conserved site [IPR018083] 0.7094017094017071 0.7960212768256032 0.4260196686636555 1.0 0.6239682015780812 3 Q9UBM7,Q14739 2 +Heat shock protein Hsp90, conserved site [IPR019805] 0.6779707747449657 0.682814581594123 0.4947240144727556 1.0 0.6655282463607912 3 P08238,P07900 2 +Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184] 0.6579382579933771 0.6775125669110134 0.4980807994076306 1.0 0.6656379346922252 2 P17301 1 +Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331] 0.653432588916457 0.597686279214282 0.5500492823099699 1.0 0.6905380600428193 3 Q12979,P11274 2 +ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629] 0.3227154575413112 0.5798516025625671 0.5620146953827982 1.0 0.6995032689313797 20 Q7L014,Q9UHI6,Q8TDD1,Q9BUQ8,Q96GQ7,Q86XP3 6 +Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.6287210584343903 0.5689227118842016 0.5694085915172153 1.0 0.705677314273472 2 P29692 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.6317876760375625 0.5255406731369835 0.5992073864271836 1.0 0.7332073504805201 3 P50570 1 +EGF-like, conserved site [IPR013032] 0.6108048511576731 0.50549910295355 0.6132083283462912 1.0 0.7440603147298095 2 Q04721 1 +S100/Calbindin-D9k, conserved site [IPR001751] 0.5931642778390305 0.445818303422338 0.6557284992599026 1.0 0.7825566452072912 2 P60903 1 +Alcohol dehydrogenase, zinc-type, conserved site [IPR002328] 0.572491730981246 0.3798432449494334 0.7040617791071386 1.0 0.8272400217503861 2 Q00796 1 +Polyprenyl synthetase, conserved site [IPR033749] 0.5831265508684829 0.3760944354141106 0.7068466910533069 1.0 0.8272400217503861 3 O95749,Q5T2R2 2 +Alpha-D-phosphohexomutase, conserved site [IPR016066] 0.5828508409153534 0.3753060782797348 0.7074328461865371 1.0 0.8272400217503861 3 Q96G03,O95394 2 +Chaperonin TCP-1, conserved site [IPR002194] 0.3522915516289326 0.350650932658813 0.7258502409336207 1.0 0.8453677504849397 8 P50991,P40227,P78371,P48643,P49368,P17987,P50990 7 +Thiolase, conserved site [IPR020613] 0.3642229510981465 0.2337243763811717 0.8151989622078244 1.0 0.9234675743760512 6 P55084 1 +Cadherin conserved site [IPR020894] 0.3944571958587227 0.1494362344691389 0.8812094217419864 1.0 0.9684559654206768 4 P19022,O60245 2 +Clathrin adaptor complex, small chain [IPR000804] 0.3640696096751197 0.1489046412418173 0.8816288788657196 1.0 0.9684559654206768 5 P61923 1 +Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131] 0.4705071664828955 0.1330524162178443 0.8941519268179388 1.0 0.9720194378433132 2 Q9NQW7 1 +D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.3781025923883083 0.1187439634938768 0.9054782050957372 1.0 0.9720194378433132 4 Q9UBQ7,Q13363,P56545 3 +IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.436879823594252 0.0838787060090152 0.9331528700302772 1.0 0.990734159002388 2 P20839 1 +Procollagen-lysine 5-dioxygenase, conserved site [IPR001006] 0.4316674893773206 0.0728253154371377 0.9419451256348372 1.0 0.990734159002388 3 Q02809 1 +Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.42282249173097 0.0679010457065467 0.9458644063227912 1.0 0.990734159002388 2 P06737 1 +Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.4222712238147619 0.067326302426708 0.9463219380815912 1.0 0.990734159002388 2 P82675 1 +Ras GTPase-activating protein, conserved site [IPR023152] 0.3951373381128792 0.0404017264453191 0.9677728538703316 1.0 0.9908240729672136 3 Q86VI3 1 +Thioredoxin, conserved site [IPR017937] 0.2198671393710627 0.0342842501745252 0.9726504840268672 1.0 0.9908240729672136 12 P13667,P30101,Q8NBS9 3 +Oxysterol-binding protein, conserved site [IPR018494] 0.2579062764312614 0.027251454495461 0.9782591761726058 1.0 0.9908240729672136 6 P22059 1 +ATPase, AAA-type, conserved site [IPR003960] 0.1959634974046828 0.0242414318161882 0.9806600300199332 1.0 0.9908240729672136 23 O15381,P35998,O75449,P62195,Q9BVQ7,P17980,P62333,Q8NB90,Q9Y4W6,P62191,Q96TA2,P55072,Q9UN37 13 +Ribosomal protein L3, conserved site [IPR019926] 0.3183572216096931 0.0124190831882696 0.9900912599755604 1.0 0.9908240729672136 2 P39023 1 +DNA mismatch repair, conserved site [IPR014762] 0.3125689084895164 0.0115005725851679 0.9908240729672136 1.0 0.9908240729672136 2 P54277 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d0b70a94fd6365dea038b53d3b6205d166829a47 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Deoxyribonuclease, TatD-related, conserved site [IPR018228]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FHF complex subunit HOOK interacting protein, KELAA motif [IPR045668]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABR", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "AP4M1", "APEX1", "APLP2", "APP", "ARHGEF7", "ARIH2", "ARRB2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CDH2", "CDK5RAP1", "CDKAL1", "CENPE", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FAM160B2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FIGNL1", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GALNS", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLA-F", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ITGA2", "ITGAV", "IVD", "KATNA1", "KDM2A", "KDSR", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAX6", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PEX6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RIOK2", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLC2A1", "SLC4A2", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPAST", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TATDN1", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABR", "AFG3L2", "AK3", "AK4", "BAZ1A", "BAZ1B", "BCR", "BPTF", "BRD2", "BRD3", "BRD4", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT8", "CDH2", "CHD1", "COPZ1", "CTBP1", "CTBP2", "CWC27", "DDX20", "DDX23", "DDX27", "DDX42", "DDX46", "DDX54", "DHCR7", "DIDO1", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJB6", "DNAJC2", "DNAJC21", "DNAJC9", "DNM2", "EEF1D", "ENO2", "EPB41L2", "EPB41L3", "FLNA", "FLNB", 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sha256:02d9344882282f45367be4e4a0919b00eb3c55019155d2d108e0029e8963e6bb +size 144205 diff --git a/interpro_domain/basic/plot_9.png b/interpro_domain/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..37efc98ad94501619940123cffa326ac2676cf8a --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d499510558934097fff6a933c0644b07b96da72f05ebaf28f1434c79dc797b98 +size 142604 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8df854d08dfc8864db760e0c6b056665f4aca311 --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dba37988e76089a8bdeefa1069b2d538e52c031cb51d367941f14f404d719e19 +size 487693 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a8946ead67425afb70773da378ad8212772762f8 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,34 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +RNA recognition motif domain [IPR000504] 65 121 5.352085384519556 8.694635247423782e-08 39.713592233009706 116.0 0.2316956716939257 0.5316884276370477 13.873754985119357 5.729331786381952 1.713447249572458 0.3950212299678106 1.0 0.0534099110641526 5.012743739710718e-05 2.46514255207862e-07 8.099956622120842e-14 +Zinc finger C2H2-type [IPR013087] 15 28 3.6418497343293783 0.000270686067703 8.96359223300971 22.56553398058253 -0.7125847169723806 0.4528377172374484 4.140861350845976 4.378685848905859 0.958367757463913 0.322433174660013 1.0 0.6255439458610363 0.4087270021998865 0.8282018112996206 0.9888407769671386 +K Homology domain, type 1 [IPR004088] 9 25 3.2064360801784577 0.0013439015808653 8.5 23.218446601941743 0.4539576731478794 0.576935027430011 4.690674491420825 1.6401661988255969 0.9187340965418598 0.3398774289684012 1.0 1.0 1.0 0.5706303062959026 0.0010690688695759 +K Homology domain [IPR004087] 9 24 3.0972299719494027 0.0019533826929865 8.029126213592233 22.796116504854368 0.328818420881894 0.600646587147133 4.351556602822176 1.3994397166034702 0.8923876485619237 0.3352669927506027 1.0 1.0 1.0 0.559801856438838 0.0008855678200528 +SAP domain [IPR003034] 6 13 2.871412458647139 0.0040864194858778 6.349514563106796 12.941747572815531 -0.8230579757827452 0.433169485582573 3.024041974152872 1.211396071124092 0.926660504961958 0.3222746404067348 1.0 0.0042324529563037 0.0161297090986061 0.0012543182247756 2.789873905099777e-05 +RNA recognition motif domain, eukaryote [IPR003954] 11 15 2.840543468123734 0.0045036734715548 4.084951456310679 13.157766990291265 0.4053633607283609 0.5044278905686779 2.611599730621696 1.3534791070715837 0.9876170990304802 0.3281969373801077 1.0 1.0 1.0 0.0015199006411711 0.002864460747413 +Myosin head, motor domain [IPR001609] 7 8 2.740169396687224 0.0061407525929291 4.390776699029126 8.03883495145631 -0.430616208806789 0.4683474380026073 2.071585945303128 1.3360013523704524 1.027601418852351 0.3224719398001398 1.0 0.1026081339138497 0.1951188871774342 0.0158941023821007 0.0004973671187583 +Linker histone H1/H5, domain H15 [IPR005818] 5 6 2.7008415095064624 0.00691642888619 4.621359223300971 6.101941747572815 -1.4616951902178734 0.1781780847215095 1.4983259581225516 0.4870120076915772 1.3151991134793464 0.2676299008151665 1.0 1.0 1.0 0.00153832558414 2.312503759377148e-06 +SH3 domain [IPR001452] 14 41 2.6401121893730197 0.008287858633925 8.412621359223301 34.599514563106794 -0.0873343944956481 0.6001758717014373 4.5941748598675405 5.423546269119778 0.8937759066152983 0.3136412847733088 1.0 0.5194717620066895 0.7699332370232862 0.7079319625284557 0.5873406057639587 +Matrin/U1-C-like, C2H2-type zinc finger [IPR003604] 5 11 2.590833571346552 0.0095743781959534 3.3932038834951457 7.70873786407767 -0.5740714135189678 0.484087264420793 2.0146917727071916 1.449010830737796 0.9099300059415022 0.3204484897971323 1.0 0.1157751708195439 0.2186221342412543 0.0029748064909912 0.0010422272070108 +Pleckstrin homology domain [IPR001849] 17 31 2.5847507340914477 0.0097449420670268 7.577669902912621 25.652912621359224 -0.0316373490872633 0.6250683324241235 5.069544167456597 6.588340411720883 0.8478431018941189 0.3044798814492656 1.0 0.631365625598012 0.8647837066853694 0.8748845390591766 0.970817131191344 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130] 6 15 2.489095210451932 0.0128068663722815 5.468446601941747 11.41747572815534 -0.7281726207623201 0.4388303162721199 2.458682754632111 2.1202869921363305 0.8994681406076788 0.3140809133543877 1.0 1.0 1.0 0.0008233445075453 0.0013613651941044 +Bromodomain [IPR001487] 8 15 2.428924766026977 0.0151436744080457 6.677184466019417 14.67233009708738 -0.7276244796788216 0.4243152584899879 3.7097567285995674 2.7131308550578574 1.0687423474505229 0.331301534807071 1.0 0.1624541869963563 0.299132167535026 0.5914976917658876 0.2554523730097116 +Myosin, N-terminal, SH3-like [IPR004009] 4 5 2.366890657005262 0.0179382316270713 2.412621359223301 4.684466019417476 -0.1448549248535419 0.5229359227697599 1.417517288923896 0.97664546553505 0.9807639625700678 0.3174032539640412 1.0 0.0479914252810258 0.0938999510605359 0.0236659942035878 5.542830198350017e-05 +Zinc finger, PHD-finger [IPR019787] 10 22 2.345554740223977 0.0189987885442071 8.934466019417476 19.902912621359224 -0.8303355972667861 0.4104688991550814 4.864481578292218 4.553915552186123 1.15464891738605 0.3323066029316399 1.0 1.0 0.1468141932972727 0.5076080911214342 0.0184969351752434 +Zinc finger, PHD-type [IPR001965] 10 23 2.3454389713302297 0.0190046895735949 9.29126213592233 21.533980582524272 -0.8032105386844209 0.421528042225622 5.007530383625769 5.074332007270643 1.1632061892335936 0.3314757026146262 1.0 1.0 0.181453052630302 0.5809341207449132 0.0380095176885234 +G-patch domain [IPR000467] 4 15 2.3349196937103915 0.0195476163435099 5.650485436893204 13.444174757281552 -0.405487239385642 0.5555291788030755 2.990953148283137 1.7637917145111943 0.8276088274784031 0.3061571987973734 1.0 1.0 0.1951188871774342 0.1003847610205272 0.0035606647558243 +BRCT domain [IPR001357] 5 9 2.242875978653448 0.0249048131875473 4.990291262135922 9.6747572815534 -0.7143354971720165 0.4253970123951497 2.5380412355248723 1.7587627185925498 0.9848552965174556 0.3342645580625223 1.0 0.1026081339138497 0.1951188871774342 0.1003847610205272 0.020271757680103 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 5 8 2.2230960011251293 0.0262093272468191 2.5849514563106797 6.101941747572815 -0.1563882835180277 0.5584151228591979 1.991503005507268 2.622586012824919 0.92042626257127 0.3048786059136322 1.0 1.0 1.0 0.3299370460914438 0.4168750029101466 +Intermediate filament, rod domain [IPR039008] 3 8 2.2063478693322987 0.0273596520935615 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 1.0 1.0 0.1951188871774342 0.1003847610205272 0.020271757680103 +PDZ domain [IPR001478] 11 29 2.1985590601302434 0.0279092907168667 5.754854368932039 22.0995145631068 -0.0374368940412008 0.6282398756154618 3.36538644878495 4.4249183808260675 0.782508143460284 0.2895172033924023 1.0 0.3928429005031874 0.6322723581240091 0.7131623095713835 0.3700752646543036 +Zinc finger, CCCH-type [IPR000571] 9 15 2.192992479794279 0.0283079209153924 6.444174757281553 15.730582524271844 -0.509040683166068 0.5138559827097335 3.3456666725815647 2.707905838392006 0.8323295492748249 0.309580088719277 1.0 0.2222355866483168 0.3958350013250431 0.1290957784683654 0.1013718771427775 +Forkhead-associated (FHA) domain [IPR000253] 5 8 2.1591636669718444 0.0308374717189752 4.322815533980583 9.66019417475728 -0.6293037727371198 0.4504386266586539 2.3296659694211708 2.1858032584444236 0.9594715936371826 0.3181954802976359 1.0 0.0100088432903632 0.0368247433715485 0.0395166683685705 0.0619922366647863 +TRASH domain [IPR011017] 4 5 2.1469243103877176 0.0317993078738343 2.0097087378640777 3.813106796116505 -0.5777047781978979 0.465505167222684 1.254081845171865 1.300307304325392 0.9925938799836542 0.319525540575421 1.0 0.0385773062479974 0.0758460972151271 2.2860654433849456e-05 0.0003337445501144 +Chromo/chromo shadow domain [IPR000953] 8 10 2.146875898263734 0.0318031628656987 4.347087378640777 9.407766990291265 -0.3647448562483869 0.5163252352695795 2.392020769411715 1.7567450771511572 0.8912812703039437 0.3063271870521043 1.0 0.1244478155008913 0.0285062952815799 0.1410845222447507 0.1423023069394473 +Zinc finger, double-stranded RNA binding [IPR022755] 5 7 2.088056499599632 0.0367927384019215 1.8907766990291264 3.6893203883495143 -0.5539908717987201 0.4804068426555486 1.17010180398548 1.36374075927808 1.0017451601504346 0.3150810210291837 1.0 0.0619434524836269 0.1203280145079081 0.0034718672031755 0.0028040242445346 +High mobility group box domain [IPR009071] 9 13 2.068273871834669 0.0386142772412956 4.128640776699029 11.550970873786408 -0.3002613814777062 0.533993717532219 2.267425531491946 1.1212094843915332 0.8981428404432965 0.3096943400990105 1.0 0.1583124314184509 0.2921659829416722 0.0536128505953338 0.0888289826938022 +Guanylate kinase-like domain [IPR008144] 3 9 2.067149693698906 0.0387200507727891 2.9975728155339807 6.963592233009709 0.5006632403339694 0.4738825144563896 2.043814711463587 1.6869386038453082 0.907662015536667 0.3076020117251588 1.0 1.0 1.0 1.0 0.5276895149825147 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 3 9 2.067149693698906 0.0387200507727891 2.9975728155339807 6.963592233009709 0.5006632403339694 0.4738825144563896 2.043814711463587 1.6869386038453082 0.907662015536667 0.3076020117251588 1.0 1.0 1.0 1.0 0.5935435236326052 +Dbl homology (DH) domain [IPR000219] 5 7 2.064065118938314 0.0390115426237225 2.1650485436893203 4.970873786407767 -0.2603834385846391 0.4983949433662193 1.675622402135014 2.7000766284689237 1.1060587808067857 0.3262483259439779 1.0 0.2336798458054532 0.4135270958140081 0.7392235469698557 0.7472648051064422 +Calponin homology domain [IPR001715] 11 30 2.04588991540938 0.0407672027568648 8.504854368932039 25.138349514563107 -0.7164062756232187 0.4508784831562523 4.107473147618039 3.395140043749966 1.1410234625396227 0.3491218583197355 1.0 1.0 1.0 0.2262454833872124 0.0438235854673598 +Zinc finger, RanBP2-type [IPR001876] 2 8 1.9832608554247275 0.0473382994441096 3.2742718446601944 8.616504854368932 0.6239078002715212 0.4100405386528319 1.463145369641179 0.7330740021954685 1.0299872364022182 0.3121093098016552 1.0 0.0981765691424607 0.0177148463510605 0.0927037920539492 0.0798154053066686 +B-box-type zinc finger [IPR000315] 1 9 1.9768193992399703 0.0480620480862938 2.150485436893204 6.019417475728155 0.1378906185367559 0.5071478683401887 1.8477682043932235 1.6174448417195804 0.9644160769127244 0.3051430714909308 1.0 0.0119629297909749 0.0435975481844182 0.2024630111897534 0.4989028149926751 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b3a46601145849daf7275bf9de1ecfa58370b920 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 2791, + "title": "Average number of proteins per term", + "value": 2.245431744894303 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a72d1e3a1feda6c0b5b5f892bbf69693109f8f7a --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a5f25032bcc950a0c4c9ac00a6ff56fe4d6802c6 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,379 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +RNA recognition motif domain [IPR000504] 0.5969534866998124 5.3520853845195555 8.694635247423782e-08 0.0002426378389849 0.0002426672697583 121 Q13283,Q8IXT5,Q9NWH9,Q9Y6M1,Q9UKM9,Q14151,O95319,P38159,P98179,Q96E39,P09012,Q9NZI8,P78332,Q15233,P26599,Q13243,P52272,Q8IY67,Q5T8P6,Q14966,Q9GZT3,P98175,Q9NTZ6,Q86V81,Q9NW13,P08579,O95628,Q01085,Q01844,O95104,P23588,Q8WUA2,P23246,Q96T37,Q08170,P08621,P19338,Q8WXF1,Q9BTD8,Q76FK4,Q15056,Q9BY77,Q13151,Q13310,Q9Y4C8,P05455,Q14498,Q15424,P11940,Q96PK6,Q12849,Q15287,P18615,Q01130,P43243,Q9P2N5,O75494,P49756,Q9UN86,P42696,Q05519,P51991,P33240,P84103,Q01081 65 +Zinc finger C2H2-type [IPR013087] 0.6210075957724999 3.641849734329379 0.000270686067703 0.5302652395387598 0.0382834317380067 28 Q5F1R6,Q7Z3K3,Q8N1G0,P17544,Q9Y467,Q14966,Q15075,Q96JM3,Q969S3,O95785,P98175,Q92785,Q96KM6,Q9H2P0,P25490 15 +K Homology domain, type 1 [IPR004088] 0.6025087816806269 3.2064360801784577 0.0013439015808653 0.9765609523715292 0.0382834317380067 25 Q96AE4,Q9Y6M1,Q8IWZ3,Q15637,O75179,Q96PU8,Q00341,Q92945,Q9NZI8 9 +K Homology domain [IPR004087] 0.6028244797996744 3.0972299719494027 0.0019533826929865 0.995734615097879 0.0382834317380067 24 Q96AE4,Q9Y6M1,Q8IWZ3,Q15637,O75179,Q96PU8,Q00341,Q92945,Q9NZI8 9 +SAP domain [IPR003034] 0.7222163460460901 2.871412458647139 0.0040864194858778 0.9999891197754064 0.0405878889148934 13 Q13435,Q8IX12,Q15424,Q9NWH9,P82979,Q14151 6 +RNA recognition motif domain, eukaryote [IPR003954] 0.6662061367050117 2.840543468123734 0.0045036734715548 0.9999966217169888 0.0424653806051003 15 Q14498,P11940,P19338,Q01130,P38159,Q96E39,Q9Y4C8,O95628,Q13310,Q01085,Q01081 11 +Myosin head, motor domain [IPR001609] 0.8078409718387527 2.740169396687224 0.0061407525929291 0.9999999658218608 0.0480079565458408 8 Q92614,Q9UM54,Q7Z406,P35580,O00159,P35579,O94832 7 +Linker histone H1/H5, domain H15 [IPR005818] 0.9122516556291412 2.7008415095064624 0.00691642888619 0.9999999961331244 0.0497362271320149 6 P16403,P10412,P16402,Q5SSJ5,Q92522 5 +SH3 domain [IPR001452] 0.463622435013457 2.6401121893730193 0.008287858633925 0.9999999999182864 0.0546841925467723 41 Q07157,Q8IZP0,A1A4S6,Q9UDY2,Q9Y5K6,Q9NZM3,Q9UKS6,Q14168,Q13813,Q8N3R9,Q9UQB8,Q15149,Q14247,Q9UNF0 14 +Matrin/U1-C-like, C2H2-type zinc finger [IPR003604] 0.7135523987400876 2.590833571346552 0.0095743781959534 0.999999999997818 0.0583164747566852 11 Q5F1R6,P43243,Q14966,Q969S3,Q5VUA4 5 +Pleckstrin homology domain [IPR001849] 0.4908712361133471 2.5847507340914473 0.0097449420670268 0.9999999999986507 0.0586647859541837 31 Q13464,Q12802,Q92888,P11274,A1A4S6,Q6WCQ1,Q96JJ3,Q9UQ16,Q9NZM3,Q9H4L5,O75116,P22059,P50570,Q01082,Q12979,Q92974,Q9Y5S2 17 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130] 0.6121629466789733 2.489095210451932 0.0128068663722815 0.9999999999999998 0.0676969016004504 15 Q8WUA2,Q9Y3C6,Q13356,P30414,Q13427,Q6UX04 6 +Bromodomain [IPR001487] 0.603106842634173 2.428924766026977 0.0151436744080457 1.0 0.0746749033089323 15 Q9UIF9,Q86U86,O60885,Q15059,Q12830,Q9NRL2,P25440,Q9UIG0 8 +Myosin, N-terminal, SH3-like [IPR004009] 0.9064827586206876 2.366890657005262 0.0179382316270713 1.0 0.0838048836754625 5 Q9UM54,P35579,Q7Z406,Q92614 4 +Zinc finger, PHD-finger [IPR019787] 0.5310684708067197 2.345554740223977 0.0189987885442071 1.0 0.085616763988941 22 Q96T23,Q9BTC0,Q8WUB8,Q12830,Q92576,Q92785,O94880,Q9UIG0,Q96L73,Q9Y2K7 10 +Zinc finger, PHD-type [IPR001965] 0.5207714633188884 2.3454389713302297 0.0190046895735949 1.0 0.085616763988941 23 Q96T23,Q9BTC0,Q8WUB8,Q12830,Q92576,Q92785,O94880,Q9UIG0,Q96L73,Q9Y2K7 10 +G-patch domain [IPR000467] 0.589066864809439 2.3349196937103915 0.0195476163435099 1.0 0.086874836329198 15 P98175,P78332,Q5T3I0,Q92917 4 +BRCT domain [IPR001357] 0.6886020244592692 2.242875978653448 0.0249048131875473 1.0 0.0972158511978246 9 P09874,P49916,P18887,Q14676,Q9NYB0 5 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.7063499678711426 2.2230960011251293 0.0262093272468191 1.0 0.1006193017137168 8 Q13464,Q12802,Q9H0H5,Q92974,Q9Y5S2 5 +Intermediate filament, rod domain [IPR039008] 0.703155027164301 2.2063478693322987 0.0273596520935615 1.0 0.1033651017333443 8 Q03252,P07197,P48681 3 +PDZ domain [IPR001478] 0.455108207784704 2.1985590601302434 0.0279092907168667 1.0 0.1044166627222186 29 Q07157,Q9NR12,Q92614,Q9UDY2,Q09666,O00233,Q14168,Q8N3R9,Q5EBL8,Q96HC4,O14745 11 +Zinc finger, CCCH-type [IPR000571] 0.5681097256075657 2.192992479794279 0.0283079209153924 1.0 0.1054838548395999 15 Q96QC0,O75152,Q9UPT8,Q5T8P6,Q9P2N5,Q9NW64,O95628,Q6PJT7,Q01081 9 +Forkhead-associated (FHA) domain [IPR000253] 0.6941826768663759 2.1591636669718444 0.0308374717189752 1.0 0.1116079174481367 8 P46013,O60934,Q12972,P55196,Q14676 5 +TRASH domain [IPR011017] 0.8546206896551508 2.1469243103877176 0.0317993078738343 1.0 0.1143848293275324 5 Q9UBW7,Q5SVZ6,Q9UHA3,Q5VZL5 4 +Chromo/chromo shadow domain [IPR000953] 0.6494061254324779 2.146875898263734 0.0318031628656987 1.0 0.1143848293275324 10 P45973,Q9P2D1,Q8TAQ2,O14646,Q14839,Q13185,Q92922,Q9HCK8 8 +Myosin tail [IPR002928] 0.9062327633756158 2.0972018876431298 0.0359757074782634 1.0 0.1248858203629765 4 P35579,Q7Z406,Q92614 3 +Zinc finger, double-stranded RNA binding [IPR022755] 0.7282682278900662 2.088056499599632 0.0367927384019215 1.0 0.1268018614636651 7 Q5F1R6,Q14966,Q969S3,Q9ULV3,Q9H3H1 5 +High mobility group box domain [IPR009071] 0.5902386309491973 2.068273871834669 0.0386142772412956 1.0 0.1309911050992177 13 P26583,Q86U86,Q00059,P17480,Q969G3,O94842,O15347,O75717,Q9NP66 9 +Guanylate kinase-like domain [IPR008144] 0.6565025103511246 2.067149693698906 0.0387200507727891 1.0 0.1309911050992177 9 Q8N3R9,Q07157,Q14168 3 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.6565025103511246 2.067149693698906 0.0387200507727891 1.0 0.1309911050992177 9 Q8N3R9,Q07157,Q14168 3 +Dbl homology (DH) domain [IPR000219] 0.7234162853913606 2.064065118938314 0.0390115426237225 1.0 0.1314990524913159 7 Q12802,Q92888,P11274,Q9NZM3,Q92974 5 +Calponin homology domain [IPR001715] 0.4371194471037967 2.04588991540938 0.0407672027568648 1.0 0.1350931805598276 30 Q86VI3,Q14315,O75369,P46940,Q5M775,Q01082,Q86VS8,P21333,Q15149,P46939,Q96ED9 11 +BAT2, N-terminal [IPR009738] 0.9853914002205072 2.0410790014309623 0.041242975212461 1.0 0.1355820304098688 2 P48634 1 +Zinc finger, RanBP2-type [IPR001876] 0.6610904346585036 1.9832608554247275 0.0473382994441096 1.0 0.1487851280951688 8 P98175,P49790 2 +B-box-type zinc finger [IPR000315] 0.6402076477301775 1.9768193992399703 0.0480620480862938 1.0 0.1502140831006116 9 O60858 1 +Protein of unknown function DUF3504 [IPR021893] 0.9669239250275689 1.9642318361337048 0.0495032124125658 1.0 0.1522008968618466 2 Q9UBW7 1 +HDGF-related, PWWP domain [IPR035496] 0.8681742967457189 1.9419227971100912 0.0521464471368178 1.0 0.1558251969580926 4 P51858,Q7Z4V5,Q9Y3E1 3 +PWWP domain [IPR000313] 0.601242718521446 1.940020751268013 0.052377168023054 1.0 0.1563472470078543 11 P51858,Q7Z4V5,Q96L73,Q9Y3E1 4 +Ribosomal protein L2, C-terminal [IPR022669] 0.9581036383682522 1.9273927019651227 0.0539307084466464 1.0 0.159958137380011 2 P62917 1 +Ribosomal Proteins L2, RNA binding domain [IPR022666] 0.9581036383682522 1.9273927019651227 0.0539307084466464 1.0 0.159958137380011 2 P62917 1 +Chromo domain [IPR023780] 0.6488836675556802 1.917657403211362 0.0551544662999492 1.0 0.1621662399116748 8 Q9P2D1,Q9HCK8 2 +Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346] 0.9523153252480704 1.9031714837485791 0.0570181728010965 1.0 0.1652520459894709 2 Q86YP4 1 +Zinc finger, RING-type [IPR001841] 0.4195965758768016 1.8944581471677588 0.0581642246150382 1.0 0.1678762677358549 31 Q14527,Q7Z6E9,Q13263,O60858,Q99496,O75150,O75592,P14373,O43164,O95628,Q13049,O15344,P19474,Q9UIG0,Q99590 15 +RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.8559740555163463 1.8917059070610505 0.0585301758641816 1.0 0.1684100214813721 4 O60858 1 +Matrin/U1-C, C2H2-type zinc finger [IPR000690] 0.7318343572400299 1.8852062883596077 0.0594019921679187 1.0 0.170259050920869 6 P43243,Q14966 2 +Laminin-type EGF domain [IPR002049] 0.943495038588762 1.8661962654471729 0.0620139113937403 1.0 0.17325408078071 2 P07942 1 +Laminin, N-terminal [IPR008211] 0.943495038588762 1.8661962654471729 0.0620139113937403 1.0 0.17325408078071 2 P07942 1 +NUC153 [IPR012580] 0.941565600882029 1.8580975264795172 0.0631551660426881 1.0 0.1750407829445308 2 Q9BSC4 1 +GRIP domain [IPR000237] 0.9410143329658214 1.8557829299910653 0.0634845046215002 1.0 0.1753143414849856 2 Q8IWJ2 1 +Zinc finger, LIM-type [IPR001781] 0.6365881785104267 1.8512071146826776 0.0641397626170934 1.0 0.1756836518391588 8 Q9NR12,Q15942,Q9UHB6,Q16527,Q96HC4 5 +EH domain [IPR000261] 0.7142982912618436 1.802367672530016 0.0714875778536532 1.0 0.1869525245608009 6 Q9NZM3,Q9H4M9,Q96D71,Q9H223 4 +Band 4.1 domain [IPR019749] 0.6081568585440875 1.7970859104337364 0.0723219821388361 1.0 0.1872455029216063 9 Q9Y2J2,O43491,Q9Y490 3 +FERM central domain [IPR019748] 0.6081568585440875 1.7970859104337364 0.0723219821388361 1.0 0.1872455029216063 9 Q9Y2J2,O43491,Q9Y490 3 +FERM domain [IPR000299] 0.6258731938875406 1.7930097298110963 0.07297136830346 1.0 0.1884024874513941 8 Q9Y2J2,O43491,Q9Y490 3 +Ubiquitin-associated domain [IPR015940] 0.5023648532793292 1.773006936774597 0.0762275574310431 1.0 0.1939390271559174 16 Q04323,Q8NBM4,Q7Z6Z7,Q9UMX0,Q14157 5 +BRK domain [IPR006576] 0.9610923503440888 1.7635389209698795 0.0778096389175979 1.0 0.1970659729755135 3 Q9P2D1 1 +Ribosome receptor lysine/proline rich [IPR007794] 0.918412348401335 1.760641795760245 0.0782990497991653 1.0 0.1972316317594499 2 Q9P2E9 1 +Zinc finger, FYVE-related [IPR017455] 0.8180231791905982 1.7342484579424988 0.0828740083406656 1.0 0.2039694508631373 4 Q15075 1 +FYVE zinc finger [IPR000306] 0.8180231791905982 1.7342484579424988 0.0828740083406656 1.0 0.2039694508631373 4 Q15075 1 +SPRY domain [IPR003877] 0.5766617101353559 1.7245011809751971 0.0846174059452198 1.0 0.207164192976411 10 P14373,O15344,Q92499,P19474 4 +B30.2/SPRY domain [IPR001870] 0.5766617101353559 1.7245011809751971 0.0846174059452198 1.0 0.207164192976411 10 P14373,O15344,Q92499,P19474 4 +WW domain [IPR001202] 0.5160191728345644 1.7038752388913794 0.0884043978295507 1.0 0.2127040296054105 14 Q8N3X1,O75400,O14776,Q13526,O60828,P46939 6 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.6891072653440257 1.6824392516650029 0.0924836954199674 1.0 0.2186788345480047 6 Q15019,Q9UHD8,Q14141 3 +Fibronectin type III [IPR003961] 0.6475332860588036 1.6821846689254252 0.0925330360448561 1.0 0.2186788345480047 7 P51610,O75147,P10586 3 +Gelsolin-like domain [IPR007123] 0.687201857643962 1.6733269152694636 0.0942629566702963 1.0 0.2220151156681833 6 O95486,O95487,Q15437,Q13045 4 +Zinc finger, MYM-type [IPR010507] 0.9357595809208707 1.6658144593449091 0.0957503752841664 1.0 0.2245708381664777 3 Q9UBW7,Q5VZL5 2 +ENTH domain [IPR013809] 0.744019206088357 1.6624548474989425 0.0964216095002634 1.0 0.2259552578633377 5 Q14677,O75146 2 +Far upstream element-binding protein, C-terminal [IPR015096] 0.888092613009922 1.6323749076995848 0.1026005317813623 1.0 0.2366595737204811 2 Q96AE4 1 +SNF2, N-terminal [IPR000330] 0.4860580184909478 1.6206247368286577 0.1050981437435127 1.0 0.240630778661316 15 Q14527,Q9P2D1,Q9NRZ9,O60264,Q14839,Q9HCK8,Q6ZRS2 7 +KOW [IPR005824] 0.6744704663725642 1.6123054439828446 0.1068954892561198 1.0 0.2430547386371127 6 P61353,Q92917,Q96A35,P61254 4 +HR1 rho-binding domain [IPR011072] 0.7324885798781577 1.610929253475695 0.1071951431114444 1.0 0.2432371092878384 5 Q13464,Q16513 2 +Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297] 0.882855567805965 1.6101608952499804 0.1073627358787165 1.0 0.2433749150120745 2 Q9Y237 1 +DnaJ domain [IPR001623] 0.4553425397702103 1.6083355485506583 0.1077617090474749 1.0 0.2435633814007703 20 Q5F1R6,Q8WXX5,O75190,Q99543,P25685,Q96EY1,O75937,Q9NXW2 8 +Kinesin motor domain [IPR001752] 0.5177210386375443 1.600688128733997 0.1094460117906153 1.0 0.245945103790344 13 Q99661,Q02241,Q9Y496,Q14807,Q86Y91,Q96Q89,O00139,P33176 8 +Isopropylmalate dehydrogenase-like domain [IPR024084] 0.7275148223035852 1.5886576497296985 0.1121377051227752 1.0 0.2507823197096679 5 P48735 1 +Double-stranded RNA-binding domain [IPR014720] 0.5145711094375963 1.5800613211288952 0.1140928240285645 1.0 0.2532277809492687 13 O95793,P18583,Q9NXV6 3 +Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422] 0.8723814773980161 1.5656933571782348 0.1174204221735348 1.0 0.2574394330607508 2 O75146 1 +Helicase, C-terminal [IPR001650] 0.3325702402873545 1.5644758348128434 0.1177058636623651 1.0 0.2578626887611154 64 Q14527,Q9P2D1,Q9NRZ9,Q7L2E3,Q7L014,Q9NY93,Q9BQ39,Q9UHI6,Q9GZR7,Q8TDD1,Q9BUQ8,Q9HCK8,Q92499,P54132,Q96GQ7,Q9NR30,Q86XP3,Q6ZRS2 18 +Lens epithelium-derived growth factor, integrase-binding domain [IPR021567] 0.8676957001102725 1.5457855950996813 0.1221563570745842 1.0 0.2643309049388525 2 Q7Z4V5 1 +Zinc finger, PARP-type [IPR001510] 0.8654906284454251 1.5364146688775366 0.1244367113412514 1.0 0.2663365501176632 2 P09874 1 +Rad60/SUMO-like domain [IPR022617] 0.8649393605292175 1.5340717033093278 0.1250120137784809 1.0 0.2669753307524803 2 P61956 1 +UBX domain [IPR001012] 0.6186231544943364 1.533896273715985 0.1250551728658755 1.0 0.2669753307524803 7 Q92575,Q9UNZ2,Q04323 3 +RecF/RecN/SMC, N-terminal [IPR003395] 0.6534895135499628 1.511283261064626 0.1307162968453341 1.0 0.2726675519397067 6 O95347,Q14683 2 +SAB domain [IPR007477] 0.8953286001326372 1.5090223862369123 0.1312930620468888 1.0 0.2729377541566948 3 Q9Y2J2 1 +Band 4.1, C-terminal [IPR008379] 0.8953286001326372 1.5090223862369123 0.1312930620468888 1.0 0.2729377541566948 3 Q9Y2J2 1 +JmjC domain [IPR003347] 0.6528289159570537 1.508094369893148 0.1315303759730399 1.0 0.2729377541566948 6 Q9Y2K7 1 +Spen paralogue and orthologue SPOC, C-terminal [IPR012921] 0.7629714326222311 1.50303882478379 0.1328290324998327 1.0 0.2733214548759713 4 Q92576,Q96T37 2 +L27 domain, C-terminal [IPR014775] 0.7076788431608398 1.4995940413375155 0.1337195921383585 1.0 0.2740171671498961 5 Q8N3R9 1 +L27 domain [IPR004172] 0.7076788431608398 1.4995940413375155 0.1337195921383585 1.0 0.2740171671498961 5 Q8N3R9 1 +SMCs flexible hinge [IPR010935] 0.7064686512305172 1.494149156090678 0.1351366383458496 1.0 0.2753039106739171 5 O95347,Q9UQE7,Q14683 3 +RBM1CTR [IPR012604] 0.854740904079399 1.4907129255946765 0.1360368810595611 1.0 0.2761301345725346 2 Q96E39 1 +Bms1/Tsr1-type G domain [IPR030387] 0.8530871003307652 1.4836798092929877 0.1378938852165034 1.0 0.2787535465551767 2 Q14692 1 +Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034] 0.8530871003307652 1.4836798092929877 0.1378938852165034 1.0 0.2787535465551767 2 Q14692 1 +AARP2CN [IPR012948] 0.8530871003307652 1.4836798092929877 0.1378938852165034 1.0 0.2787535465551767 2 Q14692 1 +SET domain [IPR001214] 0.6074115806112204 1.4760905225735876 0.1399195927966192 1.0 0.2809677854707659 7 Q15910,Q96L73 2 +RII binding domain [IPR018459] 0.8495038588754162 1.468440158289857 0.141984700008853 1.0 0.2827686749600329 2 Q02952 1 +PWI domain [IPR002483] 0.7003792706957315 1.4667352044507722 0.1424481021819037 1.0 0.2827686749600329 5 P49756,O43395 2 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.5231610896226351 1.4657184096557103 0.1427250166759965 1.0 0.2827686749600329 11 Q96AY3 1 +Immunoglobulin-like domain [IPR007110] 0.4550815628311802 1.4656191076560103 0.1427520827727288 1.0 0.2827686749600329 17 Q9BY67,Q13740,O75147,Q13308,P10586,P30511,Q9Y639,O15533,Q8WX93 9 +Disulphide isomerase [IPR005788] 0.6993448644097633 1.4620757699444231 0.1437204476944424 1.0 0.2840819897416352 5 P13667,P30101 2 +CID domain [IPR006569] 0.601041322037907 1.4431886631260564 0.1489673322343261 1.0 0.2915622891065948 7 O95104,Q9NQG5,Q96P16 3 +I/LWEQ domain [IPR002558] 0.872622001654259 1.4206927723975655 0.1554060946167457 1.0 0.3017103896761648 3 O75146,Q9Y490 2 +U-box domain [IPR003613] 0.5954247931211065 1.4141511228621355 0.1573175354373166 1.0 0.3040673416935947 7 Q7Z6E9 1 +Sec23/Sec24, trunk domain [IPR006896] 0.6868517631593752 1.4057498388070564 0.1597984218765664 1.0 0.3044350822235474 5 O95486,O95487,Q15437 3 +Zinc finger, Sec23/Sec24-type [IPR006895] 0.6868517631593752 1.4057498388070564 0.1597984218765664 1.0 0.3044350822235474 5 O95486,O95487,Q15437 3 +Sec23/Sec24, helical domain [IPR006900] 0.6868517631593752 1.4057498388070564 0.1597984218765664 1.0 0.3044350822235474 5 O95486,O95487,Q15437 3 +Sec23/Sec24 beta-sandwich [IPR012990] 0.6868517631593752 1.4057498388070564 0.1597984218765664 1.0 0.3044350822235474 5 O95486,O95487,Q15437 3 +Helicase superfamily 1/2, ATP-binding domain [IPR014001] 0.3173957470579697 1.3697758086384897 0.1707568958307841 1.0 0.3207150042151537 65 Q14527,Q9P2D1,Q9NRZ9,Q7L2E3,Q7L014,Q9NY93,Q9BQ39,Q9UHI6,Q9GZR7,Q8TDD1,Q9BUQ8,Q9HCK8,Q92499,P54132,Q96GQ7,Q9NR30,Q86XP3,Q6ZRS2 18 +ARHGEF1-like, PH domain [IPR041020] 0.8497380755445262 1.3316275149510464 0.1829826187820606 1.0 0.3348276225490608 3 Q92974,Q92888 2 +Chaperone DnaJ, C-terminal [IPR002939] 0.670295242756981 1.3309986387371162 0.1831894588435743 1.0 0.3348276225490608 5 Q96EY1,P25685 2 +GUCT [IPR012562] 0.8164277839029842 1.3278021231994293 0.1842434853620251 1.0 0.3365337484590394 2 Q9BQ39 1 +WHIM1 domain [IPR028942] 0.7181467181467153 1.3132891652177625 0.1890855280772128 1.0 0.3422423533485839 4 Q96T23,Q9NRL2,Q9UIG0 3 +WHIM2 domain [IPR028941] 0.7181467181467112 1.313289165217746 0.1890855280772183 1.0 0.3422423533485839 4 Q9NRL2,Q9UIG0,Q12830 3 +DDT domain [IPR018501] 0.7181467181467112 1.313289165217746 0.1890855280772183 1.0 0.3422423533485839 4 Q9NRL2,Q9UIG0,Q12830 3 +Histone H2A/H2B/H3 [IPR007125] 0.7170435741864202 1.3086135553308742 0.1906652868796974 1.0 0.3437640928173355 4 O75367,P16104,Q9P0M6 3 +NOPS [IPR012975] 0.8409153570443881 1.2973081253894234 0.194525189762678 1.0 0.3491445688923695 3 Q8WXF1,Q15233 2 +Rho GTPase-activating protein domain [IPR000198] 0.533957504396998 1.2856230989119792 0.1985746312499912 1.0 0.3543460247362965 8 Q07960,Q9H0H5,P11274,A1A4S6 4 +Zinc finger, GATA-type [IPR000679] 0.7114535267251099 1.2849214542573957 0.198819732976367 1.0 0.3543460247362965 4 Q86YP4,Q8WXI9 2 +FERM, C-terminal PH-like domain [IPR018980] 0.5697615034434725 1.2812622298128535 0.2001015747058816 1.0 0.3561756983444615 7 Q9Y2J2,P26038,P15311,O43491 4 +FERM, N-terminal [IPR018979] 0.5697615034434725 1.2812622298128535 0.2001015747058816 1.0 0.3561756983444615 7 Q9Y2J2,P26038,P15311,O43491 4 +Zinc finger, CXXC-type [IPR002857] 0.8037486218302384 1.2739871263678115 0.2026679786229701 1.0 0.3598259086111384 2 Q9Y2K7 1 +Zinc finger, CCHC-type [IPR001878] 0.5152590771252423 1.26492547517282 0.2058980442156455 1.0 0.3636916287844742 9 Q7Z6E9 1 +WSTF/Acf1/Cbp146 [IPR013136] 0.8007166482910675 1.2611333888655063 0.207260792796299 1.0 0.3644242219622856 2 Q9UIG0 1 +PABP, RNA recognition motif 2 [IPR045305] 0.7990628445424621 1.254125169067925 0.2097965133859758 1.0 0.3648237189160489 2 P11940 1 +Immunoglobulin I-set [IPR013098] 0.7038183608820203 1.2525687833258112 0.2103626814482044 1.0 0.3648988464399867 4 Q13308,P10586 2 +Sterile alpha motif domain [IPR001660] 0.5606290111780409 1.233954111613012 0.2172200041160819 1.0 0.3726250961819204 7 Q9Y6Y8,Q13136,Q6SZW1 3 +Chromatin target of PRMT1 protein, C-terminal [IPR025715] 0.7924476295479915 1.2261150407296637 0.2201553865592238 1.0 0.3758126506952867 2 Q86V81 1 +Brdt, bromodomain, repeat I [IPR043508] 0.8218913702784655 1.2234068376545766 0.2211760720630313 1.0 0.3763310023403869 3 Q15059,P25440 2 +NET domain [IPR027353] 0.8218913702784655 1.2234068376545766 0.2211760720630313 1.0 0.3763310023403869 3 Q15059,P25440 2 +Brdt, bromodomain, repeat II [IPR043509] 0.8218913702784655 1.2234068376545766 0.2211760720630313 1.0 0.3763310023403869 3 Q15059,P25440 2 +ROCK, Rho binding domain [IPR015008] 0.7907938257993665 1.2191186945191883 0.2227991453709452 1.0 0.3777839700670159 2 Q13464 1 +RNA helicase, DEAD-box type, Q motif [IPR014014] 0.3804720756013912 1.2181677470520031 0.2231602334219948 1.0 0.3781664914880313 24 Q7L014,Q9UHI6,Q9GZR7,Q8TDD1,Q9BUQ8,Q92499,Q96GQ7,Q86XP3 8 +Heat shock chaperonin-binding [IPR006636] 0.6414977865415566 1.2009444274021612 0.229772759000012 1.0 0.3860373559449077 5 P54727,P31948,Q9UMX0 3 +ABC-transporter extension domain [IPR032781] 0.7855567805953667 1.1969817660544446 0.2313136618902609 1.0 0.3863533395186823 2 Q9UG63 1 +MCM domain [IPR001208] 0.5862873484644919 1.1855887615813745 0.2357847425991412 1.0 0.3912989092461433 6 P33991 1 +MCM, AAA-lid domain [IPR041562] 0.5862873484644919 1.1855887615813745 0.2357847425991412 1.0 0.3912989092461433 6 P33991 1 +MCM OB domain [IPR033762] 0.5862873484644919 1.1855887615813745 0.2357847425991412 1.0 0.3912989092461433 6 P33991 1 +MCM N-terminal domain [IPR027925] 0.5862873484644919 1.1855887615813745 0.2357847425991412 1.0 0.3912989092461433 6 P33991 1 +OCRE domain [IPR041591] 0.8087989957532248 1.1726732648070295 0.2409268565941049 1.0 0.3967934781069239 3 P98175 1 +p21 activated kinase binding domain [IPR033923] 0.77976846747519 1.1725499431349915 0.240976332995785 1.0 0.3967934781069239 2 O96013 1 +Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585] 0.7794928335171218 1.1713875238852964 0.2414430448182329 1.0 0.3971772379905953 2 Q08170 1 +CD80-like, immunoglobulin C2-set [IPR013162] 0.7792171995590156 1.1702251995967112 0.2419103543636842 1.0 0.3971772379905953 2 Q9BY67 1 +FERM adjacent (FA) [IPR014847] 0.6840544215908488 1.1689215672983535 0.2424352331993291 1.0 0.3975538988597695 4 Q9Y2J2 1 +Bromo adjacent homology (BAH) domain [IPR001025] 0.6839492553778233 1.1684770620888176 0.2426143864128449 1.0 0.3976140648727247 4 P26358,Q86U86,O94776 3 +Class I myosin tail homology domain [IPR010926] 0.8067273228563537 1.164657945177988 0.2441574784458873 1.0 0.3992053440787765 3 O00159,O94832 2 +Class I myosin, motor domain [IPR036072] 0.8067273228563537 1.164657945177988 0.2441574784458873 1.0 0.3992053440787765 3 O00159,O94832 2 +FCH domain [IPR001060] 0.8027592642033277 1.1493164725660634 0.2504255081077366 1.0 0.4047119821243156 3 Q9UKS6 1 +F-BAR domain [IPR031160] 0.8027592642033277 1.1493164725660634 0.2504255081077366 1.0 0.4047119821243156 3 Q9UKS6 1 +Immunoglobulin subtype [IPR003599] 0.4713444115651634 1.1465884889694171 0.2515517361392163 1.0 0.4050845273955338 11 Q9BY67,Q13740,O75147,Q13308,P10586,Q9Y639 6 +Immunoglobulin subtype 2 [IPR003598] 0.4713444115651634 1.1465884889694171 0.2515517361392163 1.0 0.4050845273955338 11 Q9BY67,Q13740,O75147,Q13308,P10586,Q9Y639 6 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.6781577495863237 1.1440112456492362 0.2526189732694219 1.0 0.4054396517509814 4 P08238,Q12931,P07900 3 +Target SNARE coiled-coil homology domain [IPR000727] 0.4788692824111739 1.1405900362518475 0.2540405654997513 1.0 0.4072528537103996 10 O95721,O43752,Q8IZP0 3 +SANT/Myb domain [IPR001005] 0.4596045402280665 1.130185681035808 0.2583979920651658 1.0 0.412107883345073 12 Q15910,Q8IXM2,Q8TAQ2,Q99459,Q99543,Q92922,Q13330,O94776 8 +Ribosomal protein L26/L24, KOW domain [IPR041988] 0.7690187431091748 1.1272908470243848 0.2596195309950788 1.0 0.4133474677736822 2 P61254 1 +Ribosomal protein S7 domain [IPR023798] 0.766538037486215 1.1168702316530577 0.2640498143397645 1.0 0.417733012138501 2 P46782 1 +HOOK, N-terminal [IPR043936] 0.7942805166197726 1.1165889785810628 0.264170106207257 1.0 0.417733012138501 3 Q86VS8 1 +Hook, C-terminal [IPR008636] 0.7942805166197726 1.1165889785810628 0.264170106207257 1.0 0.417733012138501 3 Q86VS8 1 +Transcription factor IIS, N-terminal [IPR017923] 0.6707880824906529 1.1129211980294549 0.2657422749873737 1.0 0.4189660683674495 4 Q14241 1 +SPRY-associated [IPR006574] 0.6198603877502418 1.1034890916982625 0.2698148260834143 1.0 0.4231646628600923 5 P14373,O15344,P19474 3 +Butyrophylin-like, SPRY domain [IPR003879] 0.6198603877502418 1.1034890916982625 0.2698148260834143 1.0 0.4231646628600923 5 P14373,O15344,P19474 3 +Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.7632304299889712 1.1029913810007854 0.2700309081167411 1.0 0.4231646628600923 2 O15027 1 +Domain of unknown function DUF5600 [IPR040990] 0.7604740904079348 1.0914396985490846 0.2750794522119131 1.0 0.4270004177549775 2 Q9H4M9 1 +EH domain-containing protein, N-terminal [IPR031692] 0.7604740904079348 1.0914396985490846 0.2750794522119131 1.0 0.4270004177549775 2 Q9H4M9 1 +PDZ domain 6 [IPR041489] 0.78735408838644 1.0899144117822206 0.275750847563869 1.0 0.4278046779048129 3 Q92614 1 +Pseudouridine synthase II, N-terminal [IPR002501] 0.7599228224917273 1.0891309494752048 0.2760961434769613 1.0 0.4279072774667806 2 O60832 1 +Ran binding domain [IPR000156] 0.6646442360727984 1.087045947912143 0.2770165038732992 1.0 0.4285770855379036 4 P43487,P49792,Q9UKX7 3 +Methyl-CpG DNA binding [IPR001739] 0.6639602724577622 1.0841681351732035 0.2782902572093175 1.0 0.4295951924066401 4 P51608,O95983 2 +Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038] 0.6114695216627453 1.065828100943828 0.2865013554608469 1.0 0.4386618617787193 5 P62424 1 +CRIB domain [IPR000095] 0.7799834574028105 1.061598091759694 0.2884181803890207 1.0 0.43987712648402 3 O96013,Q9Y5S2 2 +Ubiquitin-like domain, USP-type [IPR028135] 0.749173098125685 1.0442244786037198 0.2963815441690878 1.0 0.4494759711951051 2 P51784 1 +Domain of unknown function DUF4749 [IPR031847] 0.7472436604189956 1.036188961884077 0.3001139953218776 1.0 0.4519000777412021 2 Q96HC4 1 +AP180 N-terminal homology (ANTH) domain [IPR011417] 0.7727935890117746 1.0340532267446811 0.3011112807490037 1.0 0.4530466763183123 3 O75146 1 +PPM-type phosphatase domain [IPR001932] 0.6038021857798223 1.0315047275775275 0.3023041923968317 1.0 0.4541071049405583 5 Q9P0J1 1 +Adenylate kinase, active site lid domain [IPR007862] 0.7697821891370261 1.02254108653037 0.306524876886475 1.0 0.4582276011730861 3 P27144,Q9UIJ7 2 +F-box domain [IPR001810] 0.7656221652635058 1.0066637056246197 0.3140964091309626 1.0 0.4662289292071577 3 Q9Y2K7 1 +Man1/Src1, C-terminal [IPR018996] 0.7400771775082646 1.0064151395094756 0.3142159139515097 1.0 0.4662289292071577 2 Q8NC56 1 +Enolase, C-terminal TIM barrel domain [IPR020810] 0.7392502756339656 1.0029873948620576 0.3158669431358314 1.0 0.4674361814910421 2 P09104 1 +Enolase, N-terminal [IPR020811] 0.7392502756339656 1.0029873948620576 0.3158669431358314 1.0 0.4674361814910421 2 P09104 1 +Zinc finger, B-box, chordata [IPR020457] 0.737320837927228 0.9949958098166772 0.3197383022975577 1.0 0.4717166462444223 2 P14373 1 +Gamma tubulin complex component protein, N-terminal [IPR041470] 0.7351157662623989 0.985873945119074 0.32419497387229 1.0 0.4764761306358933 2 Q9BSJ2 1 +Gamma tubulin complex component, C-terminal [IPR040457] 0.7351157662623989 0.985873945119074 0.32419497387229 1.0 0.4764761306358933 2 Q9BSJ2 1 +DEAD/DEAH box helicase domain [IPR011545] 0.3062949434925262 0.9666734291664644 0.3337073140529361 1.0 0.4845275512550495 45 Q7L014,Q7L2E3,Q96GQ7,Q9NY93,Q9BQ39,Q9UHI6,Q9GZR7,Q8TDD1,Q9BUQ8,Q92499,P54132,Q8IY37,Q9NR30,Q86XP3 14 +Valyl tRNA synthetase, anticodon-binding domain [IPR033705] 0.7301543550165333 0.9653959821600986 0.3343465131331344 1.0 0.4848192008835035 2 Q5ST30 1 +Macro domain [IPR002589] 0.6305923901916601 0.9446705154734976 0.3448271142887833 1.0 0.4945593401747144 4 Q9P0M6 1 +SMARCC, SWIRM-associated domain [IPR032448] 0.7243660418963564 0.941590712398526 0.3464022266094664 1.0 0.4951554502082565 2 Q92922 1 +SMARCC, C-terminal [IPR032451] 0.7243660418963564 0.941590712398526 0.3464022266094664 1.0 0.4951554502082565 2 Q92922 1 +SMARCC, N-terminal [IPR032450] 0.7243660418963564 0.941590712398526 0.3464022266094664 1.0 0.4951554502082565 2 Q92922 1 +AAA ATPase, AAA+ lid domain [IPR041569] 0.3745429557286049 0.9302723973326767 0.3522300656143131 1.0 0.5008018915586082 19 O15381,P35998,O75449,P62195,Q9BVQ7,P17980,P62333,Q9Y4W6,P62191,Q96TA2,P55072,Q9UN37 12 +Spt5 C-terminal domain [IPR024945] 0.7205071664829055 0.9257751176881508 0.35456286074078 1.0 0.5025891266842438 2 Q9UQ35 1 +Core histone macro-H2A, macro domain [IPR035796] 0.7202315325248063 0.9246471741064238 0.3551494660586503 1.0 0.5025891266842438 2 Q9P0M6 1 +Diacylglycerol/phorbol-ester binding [IPR020454] 0.7191289966924236 0.9201377728556271 0.3575007674718633 1.0 0.5041862769145885 2 Q9Y5S2 1 +Centrosomin, N-terminal motif 1 [IPR012943] 0.7174751929437877 0.9133808793430908 0.3610422582338606 1.0 0.5078976525860408 2 Q5VU43 1 +Clp ATPase, C-terminal [IPR019489] 0.7152701212789363 0.9043854182424228 0.365791067471561 1.0 0.5114844034634903 2 Q9H078 1 +LIS1 homology motif [IPR006594] 0.4309192337122402 0.9006600377330893 0.3677691024160425 1.0 0.5139927715789557 11 Q14978,Q13428 2 +COP9 signalosome complex subunit 7, helix I [IPR041481] 0.7116868798235887 0.8898022797691022 0.3735720622430913 1.0 0.5199087665797545 2 Q9UBW8 1 +Proteasomal ATPase OB C-terminal domain [IPR032501] 0.5688275862068892 0.8765289718198097 0.3807425334269809 1.0 0.5276527552863974 5 P62191,P17980,P62333,P62195 4 +Immunoglobulin C1-set [IPR003597] 0.5676819486565493 0.8715099342532767 0.3834757840162281 1.0 0.5290563090406786 5 P30511,O15533 2 +Lamin tail domain [IPR001322] 0.7281499862145002 0.8653063126351813 0.3868706869583591 1.0 0.532686772225348 3 P02545,Q03252 2 +NudC N-terminal domain [IPR025934] 0.7053472987872049 0.8641110840122673 0.3875268706898183 1.0 0.5333271676998436 2 Q8IVD9 1 +Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617] 0.724184833516846 0.8505598618811537 0.3950138940304333 1.0 0.5399039070709791 3 Q14241 1 +Histone H2A, C-terminal domain [IPR032454] 0.7204301075268795 0.8366401799038176 0.4027948533004291 1.0 0.5443813110780447 3 P16104,Q9P0M6 2 +Chromo domain subgroup [IPR017984] 0.7203786297955099 0.8364496467220467 0.4029019927564139 1.0 0.5443813110780447 3 Q13185 1 +Chromo shadow domain [IPR008251] 0.7203786297955099 0.8364496467220467 0.4029019927564139 1.0 0.5443813110780447 3 Q13185 1 +SWIB domain [IPR019835] 0.6981808158765098 0.8352492249999365 0.4035773992340201 1.0 0.5443813110780447 2 Q96GM5 1 +Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004] 0.7198786876206208 0.8345996629290983 0.4039431520090564 1.0 0.5443813110780447 3 Q13310,P11940 2 +Peptidase M41 [IPR000642] 0.695700110253577 0.8253059210997422 0.4091979310762006 1.0 0.5482691243300157 2 Q9Y4W6 1 +Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630] 0.7088502894954484 0.7940013283451504 0.4271946580392898 1.0 0.5610432534341011 3 Q6UB35,P13995 2 +Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631] 0.7088502894954484 0.7940013283451504 0.4271946580392898 1.0 0.5610432534341011 3 Q6UB35,P13995 2 +Transcription elongation factor S-II, central domain [IPR003618] 0.7085745795423193 0.7929917631236906 0.4277826217861118 1.0 0.5610432534341011 3 Q92576,Q9BTC0 2 +ERM family, FERM domain C-lobe [IPR041789] 0.7082988695891899 0.7919824716083408 0.4283708968355677 1.0 0.5610432534341011 3 P26038,P15311 2 +Amino acid permease/ SLC12A domain [IPR004841] 0.6857772877618735 0.7857941378764092 0.4319881014784623 1.0 0.5644563629337025 2 P55011 1 +SLC12A transporter, C-terminal [IPR018491] 0.6857772877618735 0.7857941378764092 0.4319881014784623 1.0 0.5644563629337025 2 P55011 1 +THIF-type NAD/FAD binding fold [IPR000594] 0.4417796723738137 0.7806005862246548 0.4350374468887259 1.0 0.5674165154131224 8 Q9UBT2,Q13564,Q9GZZ9,P22314 4 +NIPSNAP [IPR012577] 0.7043729585175446 0.7776410397910758 0.4367806597943025 1.0 0.5691198979859469 3 O75323 1 +Metastasis-associated protein MTA1, R1 domain [IPR035170] 0.6835722160970166 0.7770735564435628 0.4371153742719622 1.0 0.5692902517933022 2 O94776 1 +C2 domain [IPR000008] 0.3400498411525795 0.7744457610094942 0.4386672312518906 1.0 0.5707786677967491 22 P11274,Q16513,Q9NZM3,Q6WKZ4,A0FGR8,Q6P1N0,Q96PE3 7 +Ribosomal protein L11, C-terminal [IPR020783] 0.6788864388092775 0.7586188397498157 0.4480805994364967 1.0 0.5787102975600473 2 Q9Y3B7 1 +Ribosomal protein L11, N-terminal [IPR020784] 0.6788864388092775 0.7586188397498157 0.4480805994364967 1.0 0.5787102975600473 2 Q9Y3B7 1 +SWIB/MDM2 domain [IPR003121] 0.6983733112765345 0.7558368623550471 0.4497470125303726 1.0 0.5795216583436149 3 P41214,Q96GM5 2 +B-box, C-terminal [IPR003649] 0.5835631549917275 0.7529022093635558 0.4515086803929691 1.0 0.5815231781157253 4 O15344,Q9UPN9,Q13263 3 +Arf GTPase activating protein [IPR001164] 0.5817242857417423 0.7455711018802464 0.4559265450744187 1.0 0.5839793424977984 4 Q8N6T3 1 +EF-hand, Ca insensitive [IPR014837] 0.6920319823545604 0.7329471207998082 0.4635906818315305 1.0 0.5886631451282083 3 Q13813,P12814 2 +ARID DNA-binding domain [IPR001606] 0.6876206231044915 0.7171237157444578 0.4732977635834259 1.0 0.5937438395823862 3 Q8IVW6,O14497 2 +Sec24-like, trunk domain [IPR041742] 0.6875070420321522 0.7167174239074515 0.4735484725583632 1.0 0.5937438395823862 3 O95487 1 +LEM domain [IPR003887] 0.4873302728402284 0.7160685733698104 0.4739490077245469 1.0 0.5938029769643328 6 Q9Y2U8,P50402,Q8NC56 3 +Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.6844157655002421 0.7056816941769974 0.4803861074750564 1.0 0.5962113826218474 3 P51784 1 +Desmoplakin, spectrin-like domain [IPR041573] 0.5701903190983086 0.6999520470636977 0.4839572519347099 1.0 0.5987254832224183 4 Q03001,Q15149 2 +Desmoplakin, SH3 domain [IPR041615] 0.5701903190983086 0.6999520470636977 0.4839572519347099 1.0 0.5987254832224183 4 Q03001,Q15149 2 +RNA polymerase, alpha subunit [IPR000722] 0.6795545345457084 0.6884157094947749 0.4911910338665888 1.0 0.6039251584542721 3 O14802 1 +RNA polymerase Rpb1, domain 3 [IPR007066] 0.6795545345457084 0.6884157094947749 0.4911910338665888 1.0 0.6039251584542721 3 O14802 1 +RNA polymerase Rpb1, domain 5 [IPR007081] 0.6795545345457084 0.6884157094947749 0.4911910338665888 1.0 0.6039251584542721 3 O14802 1 +RNA polymerase Rpb1, domain 1 [IPR007080] 0.6795545345457084 0.6884157094947749 0.4911910338665888 1.0 0.6039251584542721 3 O14802 1 +RNA polymerase Rpb1, domain 4 [IPR007083] 0.6795545345457084 0.6884157094947749 0.4911910338665888 1.0 0.6039251584542721 3 O14802 1 +RNA polymerase, N-terminal [IPR006592] 0.6795545345457084 0.6884157094947749 0.4911910338665888 1.0 0.6039251584542721 3 O14802 1 +EGF-like domain [IPR000742] 0.5235697487415446 0.6824247784655872 0.494970392152779 1.0 0.6069694044369096 5 P07942 1 +Integrin alpha-2 [IPR013649] 0.6579382579933771 0.6775125669110134 0.4980807994076306 1.0 0.6095906857009348 2 P17301 1 +Transketolase, C-terminal domain [IPR033248] 0.6573869900771937 0.6754117110458072 0.4994142271162802 1.0 0.610541002138212 2 P29401 1 +SUI1 domain [IPR001950] 0.6571113561190957 0.6743619720138474 0.5000812133250454 1.0 0.6110887330955349 2 P41214 1 +Formin, FH2 domain [IPR015425] 0.5631549917264114 0.6724587519890963 0.5012916909445875 1.0 0.6116482863780619 4 Q27J81,O60610,Q9NSV4 3 +Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768] 0.5631549917264114 0.6724587519890963 0.5012916909445875 1.0 0.6116482863780619 4 Q27J81,O60610,Q9NSV4 3 +Plectin/S10, N-terminal [IPR005326] 0.6565600882028704 0.6722638775024486 0.5014157216886441 1.0 0.6116482863780619 2 Q15149 1 +Ribosomal protein S10 domain [IPR027486] 0.6560088202866516 0.6701676354125573 0.5027509329286972 1.0 0.6126760081832955 2 Q96GC5 1 +Zinc finger, TFIIB-type [IPR013137] 0.6557331863285512 0.6691202119126445 0.5034187977220652 1.0 0.6127526665688112 2 P29083 1 +BAG domain [IPR003103] 0.5586781181771846 0.655106219936385 0.5123993677139134 1.0 0.6185582332567181 4 O95816,O95817 2 +tRNA-binding domain [IPR002547] 0.6491179713340609 0.6441247016322363 0.5194945735754082 1.0 0.6220117352419409 2 Q12904 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.6488423373759566 0.6430892931441752 0.5201661614966118 1.0 0.6220153199387504 2 O60506 1 +Diaphanous autoregulatory (DAD) domain [IPR014767] 0.6433296582138877 0.6224868644388207 0.5336217784220321 1.0 0.6321320252280208 2 O60610 1 +ZU5 domain [IPR000906] 0.6411245865490774 0.6143035942342597 0.5390147278854323 1.0 0.6361555650177124 2 Q07157 1 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.5479867622724761 0.6141507731017953 0.5391156994864044 1.0 0.6361555650177124 4 Q9Y5X3,Q9UNH7,Q13596 3 +Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.6405733186328624 0.6122630501747679 0.5403637322202779 1.0 0.6371589254866057 2 P20020 1 +Mib-herc2 [IPR010606] 0.6394707828004326 0.6081883589124496 0.5430625545074039 1.0 0.6379156522012477 2 Q9ULT8 1 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.654382287096664 0.6009189602409283 0.5478939640750622 1.0 0.6411622866807122 3 Q96EY1 1 +GAR domain [IPR003108] 0.6325799338478415 0.5829194121597407 0.5599475519824708 1.0 0.6507023867479246 2 Q03001 1 +SWIRM domain [IPR007526] 0.5376976611969528 0.5754385583545524 0.5649947330340543 1.0 0.6556758003734078 4 Q92922 1 +Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038] 0.6287210584343903 0.5689227118842016 0.5694085915172153 1.0 0.6594271281844597 2 P29692 1 +Elongation factor 1 beta central acidic region, eukaryote [IPR018940] 0.6287210584343903 0.5689227118842016 0.5694085915172153 1.0 0.6594271281844597 2 P29692 1 +Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164] 0.6276185226019757 0.5649446017440471 0.5721114453276868 1.0 0.6621567381881941 2 Q5JTZ9 1 +Ubiquitin specific protease domain [IPR028889] 0.3298157979360963 0.5632125561706017 0.5732901538457889 1.0 0.6622735179567867 17 P40818,Q9UPT9 2 +Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394] 0.3298157979360963 0.5632125561706017 0.5732901538457889 1.0 0.6622735179567867 17 P40818,Q9UPT9 2 +La protein, xRRM domain [IPR014886] 0.6259647188533648 0.5589951982556538 0.5761649972496588 1.0 0.6653192003822084 2 P05455 1 +Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939] 0.6356423971877638 0.5381638093753198 0.5904639628867439 1.0 0.6801423526276938 3 Q96C36 1 +Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036] 0.6356423971877638 0.5381638093753198 0.5904639628867439 1.0 0.6801423526276938 3 Q96C36 1 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.4203499269956594 0.5373585309395619 0.5910199822894686 1.0 0.6802213486886214 7 Q9H4M9,P50570,Q9H223 3 +Dynamin, N-terminal [IPR045063] 0.4203499269956594 0.5373585309395619 0.5910199822894686 1.0 0.6802213486886214 7 Q9H4M9,P50570,Q9H223 3 +LEM-like domain [IPR013146] 0.6190738699007625 0.5344412495911753 0.5930362863971776 1.0 0.6819795118807264 2 P42167 1 +FAD/NAD(P)-binding domain [IPR023753] 0.4445987048346675 0.5284816455657502 0.5971650830226132 1.0 0.6858797311588943 6 Q16881,P22570 2 +Transketolase-like, pyrimidine-binding domain [IPR005475] 0.5242202208673328 0.5258925017398053 0.5989628990179334 1.0 0.6868122445660245 4 P29401,P11177 2 +Dynamin GTPase effector [IPR003130] 0.6317876760375625 0.5255406731369835 0.5992073864271836 1.0 0.6868122445660245 3 P50570 1 +GTPase effector domain [IPR020850] 0.6317876760375625 0.5255406731369835 0.5992073864271836 1.0 0.6868122445660245 3 P50570 1 +Dynamin stalk domain [IPR000375] 0.6317876760375625 0.5255406731369835 0.5992073864271836 1.0 0.6868122445660245 3 P50570 1 +Alanyl-tRNA synthetase, class IIc, core domain [IPR018165] 0.6277915632754312 0.5125641986187147 0.6082562019841165 1.0 0.6963261114592572 3 Q9BTE6,Q5JTZ9 2 +Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730] 0.6121830209481716 0.510281841511845 0.6098540224025826 1.0 0.6975830231662328 2 P38117 1 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.6116317530319639 0.508366744843589 0.6111961700020965 1.0 0.6985456635855246 2 P13674 1 +ELM2 domain [IPR000949] 0.6222857615751856 0.494874124784659 0.6206889766226151 1.0 0.7067902626494161 3 O94776 1 +Myb domain [IPR017930] 0.4088283388712095 0.486391636589737 0.626689519142912 1.0 0.712170377820793 7 Q8TAQ2,Q92922,Q99459,Q99543 4 +Alcohol dehydrogenase, N-terminal [IPR013154] 0.4075739116890867 0.4809439162056743 0.6305563593288803 1.0 0.7159816106130614 7 Q8N4Q0 1 +Methyltransferase type 11 [IPR013216] 0.511328419688835 0.4798746197822522 0.6313165492066866 1.0 0.7165532691483784 4 O43709,Q8N6R0 2 +Vps4 oligomerisation, C-terminal [IPR015415] 0.4321129652489492 0.4768707952358824 0.6334541294445719 1.0 0.7186871850730896 6 Q9UN37 1 +Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099] 0.6117088983662013 0.4615336101527307 0.644415813536587 1.0 0.7281637795872932 3 Q16881 1 +S100/CaBP-9k-type, calcium binding, subdomain [IPR013787] 0.5931642778390305 0.445818303422338 0.6557284992599026 1.0 0.7397486828756622 2 P60903 1 +PUA domain [IPR002478] 0.497571978183043 0.4324272373398761 0.6654309255481632 1.0 0.7482746628545219 4 P41214 1 +Alpha-D-phosphohexomutase, C-terminal [IPR005843] 0.5837927232634954 0.4153495313749988 0.6778860465754555 1.0 0.7613601432563768 2 Q96G03 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845] 0.5826901874310808 0.4118248110816319 0.6804678344352755 1.0 0.7630316295334889 2 Q96G03 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846] 0.5826901874310808 0.4118248110816319 0.6804678344352755 1.0 0.7630316295334889 2 Q96G03 1 +Phox homology [IPR001683] 0.314945652801163 0.3928886459828299 0.6944017278583021 1.0 0.7770951172624383 14 O60493,Q9Y5X2 2 +Domain of unknown function DUF1899 [IPR015048] 0.5866662632287238 0.3862794329995748 0.6992897308006834 1.0 0.781935867067211 3 Q9ULV4 1 +Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615] 0.5865364678176079 0.3859038939043557 0.6995678466738895 1.0 0.781935867067211 3 P51784 1 +ATP:guanido phosphotransferase, N-terminal [IPR022413] 0.5722160970231421 0.3789948062627716 0.7046917206616017 1.0 0.7857749070581423 2 P12532 1 +ATP:guanido phosphotransferase, catalytic domain [IPR022414] 0.5722160970231421 0.3789948062627716 0.7046917206616017 1.0 0.7857749070581423 2 P12532 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844] 0.5828508409153534 0.3753060782797348 0.7074328461865371 1.0 0.7882016262301896 3 Q96G03,O95394 2 +Initiation factor eIF-4 gamma, MA3 [IPR003891] 0.4027162514781238 0.3629282191553397 0.7166585060817261 1.0 0.797843594126086 6 Q53EL6,O43432 2 +La-type HTH domain [IPR006630] 0.4384570577704356 0.3572049003713939 0.7209384176161242 1.0 0.8021489362806139 5 Q6PKG0 1 +Formin, FH3 domain [IPR010472] 0.5762338020402501 0.3566044146662277 0.7213879720760805 1.0 0.8021489362806139 3 O60610,Q9NSV4 2 +Formin, GTPase-binding domain [IPR010473] 0.5762338020402501 0.3566044146662277 0.7213879720760805 1.0 0.8021489362806139 3 O60610,Q9NSV4 2 +CARG-binding factor, N-terminal [IPR012956] 0.5642227122381362 0.3547671548285435 0.7227640365283814 1.0 0.8032102615453612 2 Q14103 1 +Protein kinase domain [IPR000719] 0.2346485077016059 0.3452284248653567 0.729922650932221 1.0 0.8103477003786113 69 Q13464,Q16513,P51956,O00311,Q13308,Q2M2I8,Q13523,O96013,O95747,Q13043,Q99640,Q9H2G2,O75116,P11802,Q9Y5S2 15 +FF domain [IPR002713] 0.5705292848608959 0.3408264519210511 0.7332342357114765 1.0 0.8133770873890027 3 O14776 1 +HD/PDEase domain [IPR003607] 0.5529217199558868 0.3218002123423941 0.7476040534235939 1.0 0.8273824268663194 2 Q7Z4H3 1 +HD domain [IPR006674] 0.5529217199558868 0.3218002123423941 0.7476040534235939 1.0 0.8273824268663194 2 Q7Z4H3 1 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.5460308710032955 0.3024688998731359 0.76229463812465 1.0 0.8415998160624597 2 P51114 1 +Translation elongation factor EFTu-like, domain 2 [IPR004161] 0.3193787743620571 0.2865000942419279 0.7744951212982516 1.0 0.8529818960068121 10 O60841 1 +AGC-kinase, C-terminal [IPR000961] 0.3090116041301174 0.2814384726005982 0.7783741132103419 1.0 0.8559661741410812 12 Q13464,Q9Y5S2 2 +2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078] 0.4484280198565903 0.2797323317268093 0.7796828710492696 1.0 0.8567716750488116 4 P36957,P10515,P11182 3 +Cold-shock (CSD) domain [IPR019844] 0.5372105843439787 0.278609936975352 0.7805441859624913 1.0 0.8567716750488116 2 P67809 1 +Agenet-like domain [IPR008395] 0.5461814171491554 0.2772835243719631 0.7815624094139284 1.0 0.8567716750488116 3 P51114,Q06787 2 +Fxr1, tudor domain [IPR041560] 0.5461814171491554 0.2772835243719631 0.7815624094139284 1.0 0.8567716750488116 3 P51114,Q06787 2 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.5461814171491554 0.2772835243719631 0.7815624094139284 1.0 0.8567716750488116 3 P51114,Q06787 2 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.5461814171491554 0.2772835243719631 0.7815624094139284 1.0 0.8567716750488116 3 P51114,Q06787 2 +Aminotransferase, class I/classII [IPR004839] 0.3555064863372856 0.2764552356035961 0.7821984371304482 1.0 0.8570957092822669 7 O75600,Q8TD30,P17174,O15270,Q6YP21,P00505 6 +Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030] 0.5361080485115709 0.2756989823638686 0.7827792773058038 1.0 0.8570957092822669 2 Q99798 1 +Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573] 0.5361080485115709 0.2756989823638686 0.7827792773058038 1.0 0.8570957092822669 2 Q99798 1 +SWAP/Surp [IPR000061] 0.3748675741206547 0.2668787133629061 0.7895625466739777 1.0 0.8635066879965015 6 Q15459,Q8IX01 2 +GAT domain [IPR004152] 0.5311466372656983 0.2627996012637613 0.7927050428827227 1.0 0.8658669209379829 2 Q6ZVM7 1 +Tudor domain [IPR002999] 0.3214581607290862 0.2616619483337565 0.7935820794551631 1.0 0.8658669209379829 9 Q9Y2W6,Q15047,O75940,Q14739,Q7KZF4,Q92667,Q9Y483,Q12888 8 +SANT domain [IPR017884] 0.3144857986844728 0.236219095283287 0.8132626628528419 1.0 0.8819919436049235 9 Q8TAQ2,Q99543,Q92922,Q13330,O94776 5 +Thiolase, N-terminal [IPR020616] 0.3642229510981465 0.2337243763811717 0.8151989622078244 1.0 0.8825524839107982 6 P55084 1 +Thiolase, C-terminal [IPR020617] 0.3642229510981465 0.2337243763811717 0.8151989622078244 1.0 0.8825524839107982 6 P55084 1 +ATPase, AAA-type, core [IPR003959] 0.235497937243362 0.2207678084791163 0.8252732302481407 1.0 0.8900067950628132 35 O15381,P35998,Q8WVB6,P36776,O75449,O76031,Q9BVQ7,P17980,Q9Y4W6,P62191,Q96TA2,Q9H078,P55072,P35251,Q96QE3,Q9UN37 16 +Ubiquitin-like domain [IPR000626] 0.261175456002796 0.1981342703024955 0.8429400124829658 1.0 0.9069566595373776 18 P61956,Q9UMX0,Q15459 3 +Amidohydrolase-related [IPR006680] 0.509127770474956 0.1934534116357896 0.8466038889255065 1.0 0.9105477664705544 3 Q9BPU6 1 +HECT domain [IPR000569] 0.3038090455488795 0.1780329959510222 0.8586970626418959 1.0 0.922132936449993 8 O95071,Q7Z6Z7,Q9ULT8 3 +Domain of unknown function DUF3517 [IPR021905] 0.4889746416758402 0.1669595034599507 0.867401913154898 1.0 0.9283589378309478 2 Q9UPU5 1 +Ribosomal protein L18e/L15P [IPR021131] 0.4937862137567328 0.1636211454440282 0.8700293973908471 1.0 0.930008444319362 3 Q9P015 1 +CTLH, C-terminal LisH motif [IPR006595] 0.3987865416436889 0.1582634240653663 0.8742492282292176 1.0 0.9323766129108698 4 Q9NWU2,Q7L5Y9,Q2TAY7 3 +2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041] 0.4840132304299745 0.1573619433276642 0.8749596045566439 1.0 0.9324216328054956 2 P28331 1 +Tyrosine-protein kinase, catalytic domain [IPR020635] 0.4837375964718707 0.1568392659054711 0.8753715260686963 1.0 0.932504553151806 2 P41240 1 +Zinc finger, C3HC4 RING-type [IPR018957] 0.3930748277303896 0.146679472279659 0.8833850220823225 1.0 0.9398216690453722 4 O75150 1 +CLASP N-terminal domain [IPR024395] 0.4817356516600996 0.1422563422662053 0.8868775295641229 1.0 0.9422440749956098 3 Q14008 1 +Histidine kinase/HSP90-like ATPase [IPR003594] 0.2788275160800667 0.1271012479918897 0.8988602637198766 1.0 0.9525270571872568 9 P08238,Q12931,P07900 3 +Nuclear transport factor 2 domain [IPR002075] 0.3822510676579252 0.126131481754024 0.899627847633683 1.0 0.9525270571872568 4 Q13283 1 +Nuclear transport factor 2, eukaryote [IPR018222] 0.3822510676579252 0.126131481754024 0.899627847633683 1.0 0.9525270571872568 4 Q13283 1 +Peptidase M24 [IPR000994] 0.3022357162572432 0.1233225402762839 0.9018516925100905 1.0 0.9545195577533796 7 P12955,Q9NQH7,Q9Y5B9,P53582,Q9NQW7,Q9UQ80 6 +D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140] 0.3781025923883083 0.1187439634938768 0.9054782050957372 1.0 0.9569025088820496 4 Q9UBQ7,Q13363,P56545 3 +D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139] 0.3781025923883083 0.1187439634938768 0.9054782050957372 1.0 0.9569025088820496 4 Q9UBQ7,Q13363,P56545 3 +Ras GTPase-activating domain [IPR001936] 0.3748634824146344 0.1131635434857147 0.9099008980428788 1.0 0.9598567160011392 4 Q86VI3 1 +Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314] 0.2953353574385864 0.1083166772246576 0.9137444939358224 1.0 0.9605502382579588 7 A2RTX5,P49591,Q9BW92,P41250,P07814,Q9NP81 6 +GCF, C-terminal [IPR022783] 0.4595125601518517 0.1076417407117673 0.9142798850344412 1.0 0.9607511894318996 3 P16383 1 +MIT domain [IPR007330] 0.3701966407523133 0.1054119505790766 0.9160489337057564 1.0 0.961162621794273 4 Q9UN37 1 +Helicase/UvrB, N-terminal [IPR006935] 0.4516129032258016 0.0968158097054243 0.9228726685868632 1.0 0.9666013731995148 3 P19447,Q92900 2 +Peripheral subunit-binding domain [IPR004167] 0.4483043837882506 0.0925080640481415 0.926294384512414 1.0 0.9693616899790578 3 P10515,P11182 2 +Zinc finger, CHHC-type [IPR012996] 0.4469258340226034 0.0907522421968306 0.9276894585901 1.0 0.9704577507215028 3 P31943,P55795 2 +SGS domain [IPR007699] 0.4412899669239158 0.0894300810689949 0.9287401180060928 1.0 0.971101212251409 2 Q9Y2Z0 1 +ATP-citrate lyase/succinyl-CoA ligase [IPR005811] 0.3596249310535054 0.0891025094122599 0.9290004431068656 1.0 0.971101212251409 4 P53396,Q96I99,P53597 3 +IMP dehydrogenase/GMP reductase [IPR001093] 0.436879823594252 0.0838787060090152 0.9331528700302772 1.0 0.9736185645811228 2 P20839 1 +Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717] 0.4299889746416646 0.0757249217977878 0.9396379481892048 1.0 0.9767494602178516 2 Q02218 1 +Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861] 0.4316674893773206 0.0728253154371377 0.9419451256348372 1.0 0.9784029942861298 3 Q02809 1 +Band 7 domain [IPR001107] 0.2586132478540875 0.0721546004419811 0.942478874549988 1.0 0.9785932064244854 8 O75955,Q9UJZ1 2 +Dehydrogenase, E1 component [IPR001017] 0.4301075268817156 0.0711453241503475 0.9432820960822236 1.0 0.9790629714263616 3 P08559,Q02218 2 +Translational (tr)-type GTP-binding domain [IPR000795] 0.235001382361071 0.0689364379271416 0.9450402142244532 1.0 0.980523136765966 13 P49411,P41091,Q96RP9,Q9Y450,O00178,P46199,Q7Z2Z2,Q8N442,O60841,Q05639,Q15029,P15170 12 +Ribosomal protein S5, N-terminal [IPR013810] 0.4222712238147619 0.067326302426708 0.9463219380815912 1.0 0.9811235249575488 2 P82675 1 +Ribosomal protein S5, C-terminal [IPR005324] 0.4222712238147619 0.067326302426708 0.9463219380815912 1.0 0.9811235249575488 2 P82675 1 +Elongation factor EFG, domain V-like [IPR000640] 0.3160186613937541 0.0650207151543758 0.94815750684469 1.0 0.9826615676210658 5 Q96RP9 1 +PITH domain [IPR010400] 0.4178610804851015 0.0628648826063156 0.9498740991295946 1.0 0.9826878174371674 2 O43396 1 +Domain of unknown function DUF4217 [IPR025313] 0.4167585446526924 0.0617870437364902 0.950732421373983 1.0 0.9831397510391946 2 Q13206 1 +Rpn11/EIF3F, C-terminal [IPR024969] 0.3367346938775533 0.0595652583156577 0.9525018890636484 1.0 0.9842401971035328 4 P51665,O00487,Q7L5N1 3 +FAD dependent oxidoreductase [IPR006076] 0.3331494760066213 0.0556262560888157 0.955639547549834 1.0 0.9862068349065276 4 Q9H9P8,Q96CU9,Q8NCN5 3 +Dynamin, GTPase domain [IPR001401] 0.3315263812764862 0.0539017758706676 0.9570134217845184 1.0 0.986377463590337 4 P50570 1 +HRDC domain [IPR002121] 0.4059173152155868 0.0485277564422809 0.9612956440531256 1.0 0.9892979876667676 3 P54132 1 +Elongation Factor G, domain II [IPR041095] 0.3223513733880372 0.0448252275293238 0.9642466166389234 1.0 0.9912384187989816 4 Q96RP9 1 +CTLH/CRA C-terminal to LisH motif domain [IPR024964] 0.398676592224974 0.0429448598975215 0.965745488688574 1.0 0.9916834653899228 3 Q9NWU2,Q7L5Y9 2 +CRA domain [IPR013144] 0.398676592224974 0.0429448598975215 0.965745488688574 1.0 0.9916834653899228 3 Q9NWU2,Q7L5Y9 2 +Anticodon-binding [IPR004154] 0.295172413793107 0.0409145211881244 0.9673640409072312 1.0 0.9926150875632656 5 P41250,Q9BW92,P07814,A2RTX5 4 +RasGAP protein, C-terminal [IPR000593] 0.3951373381128792 0.0404017264453191 0.9677728538703316 1.0 0.9926696196810348 3 Q86VI3 1 +Peptidase S16, Lon proteolytic domain [IPR008269] 0.3864388092612875 0.0376106621673859 0.9699981067576626 1.0 0.9931271885402188 2 P36776 1 +Lon, substrate-binding domain [IPR003111] 0.3864388092612875 0.0376106621673859 0.9699981067576626 1.0 0.9931271885402188 2 P36776 1 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058] 0.3884753239591898 0.0359328256056371 0.9713359217124972 1.0 0.9941322176382764 3 Q5JPH6,P07814 2 +GNAT domain [IPR000182] 0.2802758620689696 0.0277194000795709 0.977885950622162 1.0 0.9980023325198984 5 P41227,Q9H9T3,Q86UY6,Q9GZZ1 4 +COMM domain [IPR017920] 0.3711055969120437 0.0261039452213003 0.979174430304651 1.0 0.9981154103426167 3 Q86X83,Q7Z4G1 2 +von Willebrand factor, type A [IPR002035] 0.2161222422725169 0.0221285954386558 0.98234537619621 1.0 0.9981154103426167 9 A3KMH1 1 +THUMP domain [IPR004114] 0.3393054024255703 0.0169868008769918 0.9864471456284762 1.0 0.9981799766883932 2 Q9NXG2 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.3462917011304058 0.0160249702114884 0.9872144709032122 1.0 0.9981799766883932 3 P04439,P01889 2 +Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378] 0.2434017760146266 0.0156247474776332 0.987533762459325 1.0 0.9981799766883932 6 Q8NC60 1 +ATP-dependent RNA helicase Ski2, C-terminal [IPR012961] 0.3106394707827907 0.0112223160487477 0.9910460752320926 1.0 0.9981799766883932 2 Q15477 1 +rRNA-processing arch domain [IPR025696] 0.3106394707827907 0.0112223160487477 0.9910460752320926 1.0 0.9981799766883932 2 Q15477 1 +SCP2 sterol-binding domain [IPR003033] 0.3245106148331909 0.0102366984152778 0.9918324390275486 1.0 0.9981799766883932 3 P51659,Q6YN16 2 +Longin domain [IPR010908] 0.3021781086297166 0.0064923641974002 0.9948198792348436 1.0 0.9994752638388944 3 O15498,P51809 2 +v-SNARE, coiled-coil homology domain [IPR042855] 0.3021781086297166 0.0064923641974002 0.9948198792348436 1.0 0.9994752638388944 3 O15498,P51809 2 +Nucleotidyl transferase domain [IPR005835] 0.2707471739729746 0.0037215014948079 0.9970306782682627 1.0 1.0 3 Q9Y5P6,Q96IJ6 2 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..92169556115bbbca7fa61044dbe06dfda25607eb --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC-type uncharacterised transport system [IPR019196]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAM10/ADAM17 catalytic domain [IPR034025]", "ADAM17, membrane-proximal domain [IPR032029]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ASCH domain [IPR007374]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abl Interactor 1, SH3 domain [IPR035725]", "Abl-interactor, homeo-domain homologous domain [IPR012849]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Active breakpoint cluster region-related protein, PH domain [IPR037865]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase [IPR006862]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin [IPR001599]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-2-macroglobulin, TED domain [IPR041813]", "Alpha-2-macroglobulin, bait region domain [IPR011625]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha-macroglobulin, receptor-binding [IPR009048]", "Alpha-macroglobulin-like, TED domain [IPR011626]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginine N-methyltransferase 2-like domain [IPR026480]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Armadillo-like helical domain-containing protein 3, C-terminal [IPR013636]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Arrestin C-terminal-like domain [IPR011022]", "Arrestin-like, N-terminal [IPR011021]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Atg6, BARA domain [IPR040455]", "Atg6/beclin, coiled-coil domain [IPR041691]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAAT/Acyl-CoA thioester hydrolase C-terminal [IPR014940]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BTB/POZ domain-containing protein KCTD11/21, C-terminal domain [IPR045763]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Basic-leucine zipper domain [IPR004827]", "Bcr-Abl oncoprotein oligomerisation [IPR015123]", "Beclin-1, BH3 domain [IPR029318]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not N-terminal domain [IPR007207]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CKK domain [IPR014797]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "CNOT4, RNA recognition motif [IPR034261]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CXC domain [IPR026489]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, N-terminal [IPR013164]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-binding protein cabin-1, MEF2-binding domain [IPR015134]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calmodulin-regulated spectrin-associated protein, CH domain [IPR022613]", "Calpain C2 domain [IPR033884]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Calsyntenin, C-terminal [IPR045588]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centromere protein H, C-terminal [IPR008426]", "Centrosomal CEP44 domain [IPR029157]", "Centrosomal protein of 290kDa, coiled-coil region [IPR032321]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Clusterin, C-terminal [IPR016015]", "Clusterin, N-terminal [IPR016014]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cupin-like domain 8 [IPR041667]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit I domain [IPR033944]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytochrome c oxidase-like, subunit I domain [IPR023616]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEP domain [IPR000591]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIX domain [IPR001158]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA mitochondrial polymerase, exonuclease domain [IPR041336]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-binding protein SMUBP-2, R3H domain [IPR034072]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family A, palm domain [IPR001098]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase III subunit RPC5, C-terminal [IPR045576]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "DhaK domain [IPR004006]", "DhaL domain [IPR004007]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Dishevelled C-terminal [IPR024580]", "Dishevelled protein domain [IPR003351]", "Disintegrin domain [IPR001762]", "Disks Large homologue 3, SH3 domain [IPR035763]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF1977, DnaJ-like [IPR015399]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF3699 [IPR022168]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4187 [IPR025239]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4371 [IPR025398]", "Domain of unknown function DUF4706 [IPR031600]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase AMFR, Ube2g2-binding region [IPR040675]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "EZH2, SET domain [IPR044439]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "EngB-type guanine nucleotide-binding (G) domain [IPR030393]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Ets domain [IPR000418]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM3C (ILEI) domain [IPR039475]", "FAM69, protein-kinase domain [IPR022049]", "FAM91, C-terminal domain [IPR028097]", "FAM91, N-terminal domain [IPR028091]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHF complex subunit HOOK interacting protein, C-terminal [IPR045669]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FUZ/MON1/HPS1, first Longin domain [IPR043972]", "FUZ/MON1/HPS1, second Longin domain [IPR043971]", "FUZ/MON1/HPS1, third Longin domain [IPR043970]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formin-binding protein 1, F-BAR domain [IPR037449]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GA-binding protein alpha subunit, N-terminal [IPR024668]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GDAP2, macro domain [IPR035793]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAF2, SH3 domain [IPR035485]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galactosyltransferase, C-terminal [IPR027791]", "Galactosyltransferase, N-terminal [IPR027995]", "Galanin [IPR008174]", "Galanin message associated peptide (GMAP) [IPR013068]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "Gid-type RING finger domain [IPR044063]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycolipid transfer protein domain [IPR014830]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAT, C-terminal dimerisation domain [IPR008906]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HCLS1-binding protein 3, PX domain [IPR037901]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Helical and beta-bridge domain [IPR010643]", "Helicase Helix-turn-helix domain [IPR029491]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Heparinase II, N-terminal [IPR032518]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase complex subunit SAP30 zinc-finger [IPR025717]", "Histone deacetylase complex subunit SAP30, Sin3 binding domain [IPR025718]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "Hypoxia induced protein, domain [IPR007667]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Impact, N-terminal [IPR001498]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Initiation factor eIF2 gamma, C-terminal [IPR015256]", "Initiation factor eIF2 gamma, GTP-binding domain [IPR044128]", "Initiation factor eIF2 gamma, domain 2 [IPR044127]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L1 transposable element, RRM domain [IPR043636]", "L1 transposable element, dsRBD-like domain [IPR035300]", "L1 transposable element, trimerization domain [IPR035301]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-N [IPR015145]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM2, LYR domain [IPR045293]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "LysM domain [IPR018392]", "Lysine-specific demethylase 4, Tudor domain [IPR040477]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MABP domain [IPR023341]", "MAGE homology domain [IPR002190]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP5, SH3 domain [IPR035601]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTF2, PHD domain 1 [IPR042014]", "MTF2, PHD domain 2 [IPR042015]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Macroglobulin domain MG3 [IPR041555]", "Macroglobulin domain [IPR002890]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial ABC-transporter, N-terminal five TM domain [IPR032410]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Mvd1, C-terminal [IPR041431]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH dehydrogenase subunit 5, C-terminal [IPR010934]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal [IPR001516]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit [IPR001750]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFA6, LYR domain [IPR045299]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NOT4, modified RING finger, HC subclass (C4C4-type) [IPR039515]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NT-type C2 domain [IPR019448]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDE domain [IPR006964]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nas2, N-terminal [IPR040815]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Nck1, SH2 domain [IPR035882]", "Nck1, SH3 domain 1 [IPR035562]", "Nck1, SH3 domain 2 [IPR035564]", "Nck1, SH3 domain 3 [IPR035565]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Neuropilin, C-terminal [IPR022579]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Notch domain [IPR000800]", "Notch, C-terminal [IPR024600]", "Notch, NOD domain [IPR010660]", "Notch, NODP domain [IPR011656]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Olduvai domain [IPR010630]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRELI/MSF1 domain [IPR006797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PUA domain [IPR002478]", "PUB domain [IPR018997]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Paired DNA-binding domain [IPR043182]", "Paired domain [IPR001523]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Palmitoyltransferase, DHHC domain [IPR001594]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Patatin-like phospholipase domain [IPR002641]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M12B, ADAM/reprolysin [IPR001590]", "Peptidase M12B, propeptide [IPR002870]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plus-3 domain [IPR004343]", "Pointed domain [IPR003118]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polycomb repressive complex 2 subunit EZH1/EZH2, tri-helical domain [IPR041343]", "Polycomb-like MTF2 factor 2, C-terminal domain [IPR025894]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET CXC domain [IPR041355]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein disulfide-isomerase A5, N-terminal TRX-like b domain [IPR041865]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase B alpha, catalytic domain [IPR034676]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Protocadherin [IPR013585]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine 5'-phosphate oxidase, putative [IPR011576]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal [IPR019576]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM7, RNA recognition motif [IPR034500]", "RBM8, RNA recognition motif [IPR033744]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RFX1 transcription activation region [IPR007668]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIO kinase [IPR000687]", "RIO2 kinase winged helix domain, N-terminal [IPR015285]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 2-O ribose methyltransferase, substrate binding [IPR013123]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "RecQ mediated genome instability protein, DUF1767 [IPR033472]", "RecQ mediated genome instability protein, N-terminal [IPR013894]", "Recq-mediated genome instability protein 1, C-terminal OB-fold domain [IPR032199]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-activating protein, FF domain [IPR032835]", "Rho GTPase-activating protein, pG1 and pG2 domain [IPR045786]", "Rho GTPase-activating protein, pG1 domain [IPR039007]", "Rho GTPase-activating protein, pG2 domain [IPR039006]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Riboflavin kinase domain, bacterial/eukaryotic [IPR015865]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF4, RNA recognition motif [IPR034369]", "SCAF8, RNA recognition motif [IPR034370]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMG1, PIKK catalytic domain [IPR039414]", "SMYD3, SET domain [IPR044420]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX8/Mvp1, PX domain [IPR035704]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase Rio2 [IPR030484]", "Serine/threonine-protein kinase SMG1, N-terminal [IPR035175]", "Serine/threonine-protein kinase greatwall, catalytic domain [IPR037638]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Signal transduction histidine kinase-related protein, C-terminal [IPR004358]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein LSm5 [IPR033871]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm8 [IPR034103]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "SoHo domain [IPR003127]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin 4, PX domain [IPR034902]", "Sorting nexin 8/Mvp1, BAR domain [IPR045734]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-4, BAR domain [IPR037430]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfatase-modifying factor enzyme [IPR005532]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulfotransferase domain [IPR000863]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Syndetin, C-terminal [IPR019514]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TFIIH p62 subunit, N-terminal [IPR013876]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THAP-type zinc finger [IPR006612]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Tectonic domain [IPR011677]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Tesmin/TSO1-like CXC domain [IPR033467]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat protein 7, N-terminal [IPR045819]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription factor Tfb2, C-terminal domain [IPR040662]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 131-like, N-terminal [IPR022113]", "Transmembrane protein 131-like, conserved domain [IPR045695]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBAC2, UBA domain [IPR041928]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UBXN6, PUB domain [IPR042774]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glucuronate decarboxylase N-terminal [IPR021761]", "UDP-glycosyltransferase family, conserved site [IPR035595]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific peptidase 1 [IPR033815]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-specific peptidase 38 [IPR033840]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting protein 36, GLUE domain [IPR021648]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 13D, UBA domain [IPR041969]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar protein sorting-associated protein 54, N-terminal [IPR019515]", "Vacuolar protein sorting-associated, VPS28, C-terminal [IPR017899]", "Vacuolar protein sorting-associated, VPS28, N-terminal [IPR017898]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Vinexin, SH3 domain 1 [IPR035609]", "Vinexin, SH3 domain 2 [IPR035608]", "Vinexin, SH3 domain 3 [IPR035607]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vps72/YL1, C-terminal [IPR013272]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YegS/DAGK, C-terminal domain [IPR045540]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, AN1-type [IPR000058]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C2HC5-type [IPR009349]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, HIT-type [IPR007529]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA capping enzyme, C-terminal [IPR013846]", "mRNA capping enzyme, adenylation domain [IPR001339]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAK1", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "APLP2", "APMAP", "APOBEC3C", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC10", "ARMCX3", "ARMT1", "ARRB2", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GALT1", "B4GALT3", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAP18", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCKDK", "BCR", "BCS1L", "BECN1", "BEND3", "BIRC6", "BLM", "BLVRA", "BMS1", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C10orf76", "C1orf198", "C1orf35", "C2CD2", "C2CD2L", "C2CD5", "C3orf58", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CARM1", "CARS", "CASK", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC93", "CCDC97", "CD109", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPH", "CENPV", "CEP170", "CEP290", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLSTN3", "CLTC", "CLU", "CLUH", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT3", "CNOT4", "CNPY2", "COA3", "COASY", "COIL", "COLEC12", "COMMD2", "COMMD6", "COMMD8", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CROT", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC22", "CWC27", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCK", "DCP1A", "DCP1B", "DCTN1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC2H1", "EARS2", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM129B", "FAM160B2", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1", "FNBP4", "FNDC3A", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GAK", "GAL", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP2", "GDE1", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH11", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPRASP2", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HMBS", "HMG20A", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HS1BP3", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPBP1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "IAH1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPACT", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "ISOC2", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPK1", "ITSN2", "IVD", "IWS1", "JAM3", "JMJD6", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LRSAM1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYRM2", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAEA", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED25", "MEPCE", "METAP1", "METAP2", "METTL13", "METTL7B", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD8", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRM3", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL2", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTF2", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA40", "NAA50", "NADSYN1", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCEH1", "NCK1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "ND5", "NDE1", "NDUFA10", "NDUFA2", "NDUFA6", "NDUFA9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OBSL1", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAX6", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCM1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDXK", "PDZD11", "PDZD8", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX6", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PICALM", "PIGG", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "POP1", "POR", "PPAN", "PPAT", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRELID3B", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUF60", "PUM3", "PUS1", "PUS7", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYCR3", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "R3HCC1", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOK2", "RIOX2", "RIPK1", "RMI1", "RMND1", "RNASEH2A", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRP12", "RRP7A", "RSF1", "RSL24D1", "RTCA", "RTF1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAMM50", "SAP30", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SC5D", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCLY", "SCML2", "SCO2", "SCP2", "SCRIB", "SCYL1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC25A25", "SLC27A4", "SLC2A1", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAGLN2", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCTN3", "TDRKH", "TECR", "TEDC1", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THAP11", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIMELESS", "TIMM10B", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM131", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOP1", "TOP2A", "TOP2B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSR1", "TSTA3", "TTC4", "TTC7B", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBL5", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UCK2", "UGDH", "UGGT1", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13D", "VPS16", "VPS18", "VPS28", "VPS29", "VPS36", "VPS37B", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "VWA8", "WAPL", "WARS", "WASF2", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "WRN", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YIPF4", "YKT6", "YME1L1", "YTHDC1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZNF687", "ZNHIT2", "ZPR1", "ZYX"], "leading_proteins": ["AAK1", "AARS2", "AARSD1", "ABCF2", "ABI1", "ABR", "ACLY", "ACO2", "ACTN1", "ADNP", "AFDN", "AFG3L2", "AHNAK", "AIMP1", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "ALCAM", "ALYREF", "ANKHD1", "ANKRD17", "ARFGAP1", "ARHGAP1", "ARHGAP10", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID3B", "ATAD5", "ATF7", "ATP2B1", "BAG2", "BAG3", "BAIAP2", "BAP18", "BAZ1A", "BAZ1B", "BAZ2A", "BCR", "BLM", "BMS1", "BPTF", "BRD2", "BRD3", "BRD4", "BUD23", "CADM1", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CD2AP", "CDC42BPB", "CDC5L", "CDC7", "CDK4", "CDKN2AIP", "CELF2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHD8", "CHTF18", "CIZ1", "CKAP5", "CKMT1A*", "CLINT1", "CLPB", "CLPX", "CNOT4", "COMMD2", "COMMD6", "COPS6", "COPS7A", "CORO1C", "CSK", "CSRP2", "CSTF2", "CTBP1", "CTBP2", "CTTN", "CWC27", "DBT", "DDX1", "DDX10", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX42", "DDX46", "DDX50", "DDX54", "DDX56", "DHX30", "DHX37", "DIAPH1", "DIAPH3", "DIDO1", "DKC1", "DLAT", "DLST", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJB6", "DNAJC2", "DNAJC21", "DNAJC8", "DNAJC9", "DNM2", "DNM3", "DNMT1", "DPF2", "DPYSL5", "DST", "EARS2", "EEA1", "EEF1A2", "EEF1D", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2D", "EIF2S3", "EIF4B", "EIF4G3", "EIF4H", "EIF5B", "ELMO2", "ELOA", "ELP3", "EMD", "ENO2", "EPB41L2", "EPB41L3", "EPRS", "ERCC3", "ESYT2", "ETFB", "EWSR1", "EZH2", "EZR", "FDXR", "FKBP10", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FNBP4", "FOXRED1", "FUBP1", "FXR1", "G3BP1", "G3BP2", "GARS", "GATAD2A", "GATAD2B", "GCAT", "GCC2", "GCFC2", "GFM1", "GID8", "GMPPA", "GMPPB", "GOT1", "GOT2", "GPATCH4", "GPKOW", "GPT2", "GRHPR", "GRSF1", "GSPT1", "GTF2E1", "GTPBP1", "GUF1", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "HADHB", "HBS1L", "HCFC1", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDLBP", "HECTD1", "HELLS", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HLA-A", "HLA-B", "HLA-F", "HLTF", "HMG20A", "HMGB2", "HMGB3", "HNRNPA0", "HNRNPA3", "HNRNPD", "HNRNPH1", "HNRNPH2", "HNRNPM", "HOOK2", "HOOK3", "HP1BP3", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HUWE1", "IDH2", "IGF2BP1", "IGF2BP2", "IMPDH1", "INF2", "INPP4A", "IQGAP1", "IQGAP3", "ITGA2", "ITSN2", "KATNA1", "KDM2A", "KHSRP", "KIF18B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KYAT3", "L2HGDH", "LAMB1", "LARP1", "LBR", "LEMD2", "LEMD3", "LIG3", "LIMA1", "LMNA", "LMNB2", "LONP1", "MAEA", "MATR3", "MBD3", "MCM4", "MDC1", "MECP2", "METAP1", "METTL13", "MID1", "MKI67", "MPP2", "MPP5", "MPRIP", "MRPL11", "MRPL15", "MRPL24", "MRPL48", "MRPS5", "MSN", "MTA1", "MTA2", "MTF2", "MTHFD1L", "MTHFD2", "MTIF2", "MYCBP2", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA40", "NAA50", "NAE1", "NBN", "NCL", "NDUFS1", "NEFM", "NEK3", "NELFE", "NES", "NIPSNAP2", "NKTR", "NOA1", "NOL10", "NOL8", "NOLC1", "NONO", "NPTN", "NSD1", "NSFL1C", "NUDCD3", "NUP153", "NUP50", "NVL", "OBSL1", "OGDH", "OSBP", "OSBPL3", "OXSR1", "P4HA1", "PA2G4", "PABPC1", "PABPC4", "PACSIN2", "PACSIN3", "PAK4", "PALLD", "PARP1", "PBRM1", "PDCD4", "PDE4DIP", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDZD11", "PEPD", "PGM2", "PGM3", "PHF10", "PHF14", "PHF3", "PIN1", "PIN4", "PJA2", "PKMYT1", "PKN2", "PLEC", "PLOD1", "POGZ", "POLDIP3", "POLR3A", "PPFIA1", "PPIG", "PPIL1", "PPIL2", "PPIL4", "PPP1R10", "PPP1R8", "PQBP1", "PRPF3", "PRPF40A", "PRPF4B", "PRRC2A", "PSMC1", "PSMC2", "PSMC3", "PSMC5", "PSMC6", "PSMD14", "PSMD7", "PSMD9", "PSPC1", "PTBP1", "PTK7", "PTPRF", "PYCR2", "QKI", "RAB11FIP1", "RACGAP1", "RAD23B", "RALY", "RANBP1", "RANBP2", "RAVER1", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM42", "RBM6", "RBMX", "RBMXL1", "REPS1", "RFC1", "RNF2", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RPL26", "RPL27", "RPL7A", "RPL8", "RPRD1A", "RPRD1B", "RPS5", "RRBP1", "RSF1", "RSL24D1", "S100A10", "SAFB", "SAFB2", "SALL2", "SARM1", "SARNP", "SARS", "SARS2", "SCAF11", "SCAF4", "SEC16A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEPT2", "SEPT6", "SEPT9", "SETDB1", "SF1", "SF3A1", "SF3B2", "SFPQ", "SKIV2L", "SLC12A2", "SLC9A3R1", "SLIRP", "SLK", "SLTM", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMNDC1", "SMU1", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPB2", "SNX1", "SNX3", "SNX5", "SNX6", "SNX8", "SON", "SPATA5L1", "SPECC1", "SPTAN1", "SPTBN1", "SPTLC2", "SRCAP", "SRRM2", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SSB", "STAU1", "STIP1", "STK4", "STOML2", "STX6", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SUMO2", "SUPT16H", "SYNCRIP", "TAPBP", "TARS2", "TARSL2", "TCERG1", "TCOF1", "TDRKH", "TERF2IP", "TFAM", "THUMPD1", "TIAL1", "TJP1", "TJP2", "TKT", "TLN1", "TMPO", "TOM1L2", "TOX4", "TP53BP1", "TRAP1", "TRIM13", "TRIM21", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIT1", "TUBGCP2", "TUFM", "TXNL1", "TXNRD1", "U2AF1", "UBA1", "UBA2", "UBA5", "UBAC2", "UBAP2L", "UBQLN1", "UBR5", "UBTF", "UBXN1", "UBXN4", "UPF1", "USP11", "USP22", "USP24", "USP8", "UTRN", "VAMP7", "VARS2", "VCP", "VPS4A", "VWA8", "WDHD1", "WIZ", "XPNPEP1", "XPNPEP3", "XRCC1", "YBX1", "YKT6", "YME1L1", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H4", "ZMYM1", "ZMYM2", "ZMYM4", "ZNF318", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZYX"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a8c228fc0fa201a28d3aaf420029ffca9c12c53e --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Kinesin-like protein [IPR027640]", "1": "Heat shock protein 70 family [IPR013126]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..dfc8a1bf1a1e7ad1bea99f3fceb841ab0a291a06 --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2d634d832cfed9153dd57504390e341cc44adb1a20a9ef2dc238c893b6d11560 +size 187377 diff --git a/interpro_family/advanced/plot_1.png b/interpro_family/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..500daf7ad864ccf114480013de3ee9a25366475c --- /dev/null +++ b/interpro_family/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3c7b3eda8415aba1c681ef557936afa0be6ce3e04cd9ee18f807a04398793e7b +size 191267 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d2e1a7bd431cedcce34f57ba70fe78edd8187487 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Kinesin-like protein [IPR027640]", "1": "Heat shock protein 70 family [IPR013126]", "2": "26S proteasome regulatory subunit P45-like [IPR005937]", "3": "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "4": "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4e3afa0aaabbd442165b4d6c52a2017a28826757 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d914dfd710e68922223cf063241eced27e2a905b5cfefb0828b481335524a8f9 +size 132352 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..ae83f073e7a53c731110febbb3caf03d074cad29 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eb06a1bcdf6d14c05d6940f5f428d88be821ab8f0935603a2d6c80b0a2cb9853 +size 136313 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..b7e899ec154a82212f21a4f60e3ee4a7d67f50d1 --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dc731e22182d785e24de9b68e8b0d61df5f74a372b38a4b8ebe7f2e69dda0eb9 +size 146802 diff --git a/interpro_family/basic/plot_3.png b/interpro_family/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..7703054c2249edcf1c757a7e7df24c5e57b6c210 --- /dev/null +++ b/interpro_family/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5840345e7e1ce8b38b82db87c30ec2df77e78132b62d2e3e2255bfbbe45b7380 +size 145614 diff --git a/interpro_family/basic/plot_4.png b/interpro_family/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..3261eb2d753248c319f41d7117ba364bf832dd13 --- /dev/null +++ b/interpro_family/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f6679cf60b546e70791490fc274301b1d2af85b08c4a5b9c586a477e8a687d1c +size 143301 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..2aaf7817ffbc56f30a87f1aa728da47fe6d6322f --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1e79a2052e1d3b371cdb14f7fdc615963c23629fb8e9d08123663cb78261550b +size 566350 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f16f7913d036cbd1a1df678a401e3d61e5401f22 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Linker histone H1/H5 [IPR005819] 4 5 2.389999918224467 0.0168483765501203 4.014563106796117 4.956310679611651 -1.4175513233889876 0.1832168833940027 1.2501578748449933 0.257006630911632 1.3241307402406013 0.2675502959031997 1.0 1.0 1.0 0.0084157616576464 1.554575126715766e-06 +Kinesin-like protein [IPR027640] 7 9 2.249373848398016 0.0244887209874034 3.8470873786407767 9.157766990291265 -0.3064643501114357 0.5939785273457092 2.2904224950775363 1.6914585146764682 0.7331515470097483 0.2890038059304988 1.0 1.0 1.0 1.0 0.6990268049674585 +Heat shock protein 70 family [IPR013126] 6 10 2.04187738612514 0.0411636954671221 5.157766990291262 9.618932038834952 -0.5977526314899951 0.5182608346902362 2.6978709448427782 0.6407904897015557 0.7298098612304945 0.3042104761407978 1.0 1.0 1.0 0.2577455317022596 0.113339965404402 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0ca7e7209970af6f98bbce196e61444a8bf96f13 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 2775, + "title": "Average number of proteins per term", + "value": 1.2976576576576577 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..edaef76770926a6fcbb01a00ffad6f1b60b35ca2 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f187a956bc8468fa1f2b17aa27e1faaaaa3b74f8 --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,135 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Linker histone H1/H5 [IPR005819] 0.9120000000000004 2.389999918224467 0.0168483765501203 1.0 0.0582244644166676 5 P16403,P10412,Q92522,P16402 4 +Kinesin-like protein [IPR027640] 0.6897996587237036 2.249373848398016 0.0244887209874034 1.0 0.0737041157492781 9 Q99661,Q02241,Q9Y496,Q14807,Q86Y91,Q96Q89,P33176 7 +Heat shock protein 70 family [IPR013126] 0.6310757041328163 2.0418773861251394 0.0411636954671221 1.0 0.1034803401578474 10 P34932,P0DMV9,O95757,P54652,P11142,Q9Y4L1 6 +Protein PRRC2 [IPR033184] 0.9853914002205072 2.0410790014309623 0.041242975212461 1.0 0.1034803401578474 2 P48634 1 +Isocitrate dehydrogenase NADP-dependent [IPR004790] 0.976019845644986 2.002131257436351 0.0452706165579459 1.0 0.1090503133231771 2 P48735 1 +Ribosomal protein L2 [IPR002171] 0.9581036383682522 1.9273927019651227 0.0539307084466464 1.0 0.1221833567557038 2 P62917 1 +Snf7 family [IPR005024] 0.6946748231158622 1.9208471621582 0.0547509787022697 1.0 0.1230443613455697 7 Q9HD42,Q9H444,Q9UQN3,Q9Y3E7 4 +THRAP3/BCLAF1 family [IPR029199] 0.9534178610804868 1.9077877705071489 0.0564186520381504 1.0 0.125249407524694 2 Q9NYF8 1 +Transcriptional repressor p66 [IPR040386] 0.9523153252480704 1.9031714837485791 0.0570181728010965 1.0 0.1261765785670199 2 Q86YP4 1 +Nuclear pore complex protein [IPR026054] 0.9484564498346272 1.8870045632110903 0.0591597118917901 1.0 0.1290630507073252 2 P49790 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666] 0.7874115768940333 1.8548063022620704 0.063623891760268 1.0 0.1354998462277389 5 Q9Y3C6,Q13356,Q6UX04 3 +SCAMP [IPR007273] 0.901598676957001 1.6895902647865166 0.0911063697027194 1.0 0.1715197937076299 2 O15127 1 +Septin [IPR016491] 0.6891072653440257 1.6824392516650029 0.0924836954199674 1.0 0.1735241749766124 6 Q15019,Q9UHD8,Q14141 3 +Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101] 0.8825799338478498 1.6089913442606794 0.1076182343125153 1.0 0.1930449904442341 2 P29966 1 +Luc7-related [IPR004882] 0.8762403528114657 1.582081717494448 0.1136309166833098 1.0 0.1994432289323414 2 Q9Y383 1 +Adenylate kinase/UMP-CMP kinase [IPR000850] 0.7259090751719876 1.5814618300886831 0.1137724797837465 1.0 0.1994432289323414 5 P27144,Q9UIJ7 2 +Sla2 family [IPR030224] 0.8723814773980161 1.5656933571782348 0.1174204221735348 1.0 0.2036510447072245 2 O75146 1 +Prefoldin beta-like [IPR002777] 0.7733201486325603 1.5467041444966956 0.1219346032693937 1.0 0.2092569722155644 4 Q9NUG6,O15212 2 +Filamin family [IPR044801] 0.8963330576233796 1.5129266804716492 0.1302982838901485 1.0 0.2194039671087148 3 Q14315,O75369 2 +Ribosomal protein L24e-related [IPR000988] 0.8539140022050822 1.487196419244592 0.1369629415228848 1.0 0.2270443027037069 2 Q9UHA3 1 +Ribosome biogenesis protein Bms1/Tsr1 [IPR039761] 0.8530871003307652 1.4836798092929877 0.1378938852165034 1.0 0.2280426290082223 2 Q14692 1 +Adenylate kinase 3/4, mitochondrial [IPR028586] 0.8442668136714431 1.446164918604799 0.1481309507983363 1.0 0.2409515758882669 2 P27144 1 +Structural maintenance of chromosomes protein [IPR024704] 0.7415885273028041 1.4126110694741894 0.1577701124972099 1.0 0.2515956983094102 4 O95347,Q9UQE7,Q14683 3 +Tight junction protein ZO [IPR005417] 0.8310363836824688 1.389893799337377 0.1645611287989052 1.0 0.2593169406115628 2 Q07157 1 +Sec13/Seh1 family [IPR037363] 0.8244211686879812 1.3617685431697817 0.173270941947536 1.0 0.2684683773893983 2 P55735 1 +UBAP2/protein lingerer [IPR022166] 0.823042998897486 1.3559106247683528 0.1751276065787976 1.0 0.2704391253512317 2 Q14157 1 +Ezrin/radixin/moesin-like [IPR000798] 0.5697615034434725 1.2812622298128535 0.2001015747058816 1.0 0.2969421763683537 7 Q9Y2J2,P26038,P15311,O43491 4 +High mobility group protein HMGN [IPR000079] 0.8051267916207259 1.2798318879509265 0.2006042664139931 1.0 0.2972317013989175 2 P05204 1 +Dynein 1 light intermediate chain [IPR008467] 0.7996141124586529 1.2564610052573495 0.2089488754112773 1.0 0.3066277785649364 2 O43237 1 +Dynein family light intermediate chain [IPR022780] 0.7996141124586529 1.2564610052573495 0.2089488754112773 1.0 0.3066277785649364 2 O43237 1 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.7990628445424621 1.254125169067925 0.2097965133859758 1.0 0.3075463944247664 2 P11940 1 +Ribosomal protein S11 [IPR001971] 0.7965821389195332 1.243616951273579 0.2136405743789753 1.0 0.3118635422944011 2 P82912 1 +Rho-associated protein kinase 1/2 [IPR020684] 0.7907938257993665 1.2191186945191883 0.2227991453709452 1.0 0.3218467612724482 2 Q13464 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936] 0.8144355177099598 1.194499309919271 0.2322827104915563 1.0 0.3302549095329913 3 Q9Y3C6 1 +Mini-chromosome maintenance protein [IPR031327] 0.5862873484644919 1.1855887615813745 0.2357847425991412 1.0 0.334339632454071 6 P33991 1 +Heat shock protein Hsp90 family [IPR001404] 0.6781577495863237 1.1440112456492362 0.2526189732694219 1.0 0.3492863232798435 4 P08238,Q12931,P07900 3 +Ribosomal protein L15 [IPR030878] 0.7717750826901841 1.138880283191391 0.2547530903553605 1.0 0.3510128231063185 2 Q9P015 1 +Ribosomal protein S5/S7 [IPR000235] 0.766538037486215 1.1168702316530577 0.2640498143397645 1.0 0.36014624364759 2 P46782 1 +Abr/Bcr [IPR037769] 0.7640573318632822 1.106459406862447 0.2685277246416058 1.0 0.3645618570843718 2 P11274 1 +26S proteasome regulatory subunit P45-like [IPR005937] 0.5689845474613647 1.1018328259145551 0.2705343565693741 1.0 0.3663898679746281 6 P35998,P62195,P17980,P62333,P62191 5 +Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492] 0.7890815300469776 1.0965614383917708 0.2728331521742739 1.0 0.3682842514604059 3 P62424 1 +Ribosomal protein L4/L1e [IPR002136] 0.7607497243660755 1.092594274226516 0.2745719778022293 1.0 0.3692494196799106 2 Q9BYD3 1 +Ran binding protein RanBP1-like [IPR045255] 0.6646442360727984 1.087045947912143 0.2770165038732992 1.0 0.3713627044678286 4 P43487,P49792,Q9UKX7 3 +RNA-binding protein 26/27 [IPR045137] 0.7588202866593173 1.0845150774721983 0.278136485550144 1.0 0.3723245284137239 2 Q5T8P6 1 +Ras GTPase-activating protein-binding protein [IPR039539] 0.7568908489526092 1.0764426208360447 0.2817293496436694 1.0 0.3761334996266183 2 Q13283 1 +Protein phosphatase 2C family [IPR015655] 0.6038021857798223 1.0315047275775275 0.3023041923968317 1.0 0.395210632445283 5 Q9P0J1 1 +Adenylate kinase subfamily [IPR006259] 0.7697821891370261 1.02254108653037 0.306524876886475 1.0 0.3984451415112542 3 P27144,Q9UIJ7 2 +Protein disulphide isomerase [IPR005792] 0.7659032824595824 1.0077356593826392 0.3135813811390813 1.0 0.4056340148944108 3 P13667 1 +Enolase [IPR000941] 0.7392502756339656 1.0029873948620576 0.3158669431358314 1.0 0.4076887289311313 2 P09104 1 +Plakin [IPR043197] 0.5955214963819041 0.9945521681622184 0.3199541208791419 1.0 0.4111250576277542 5 Q03001,Q15149,P58107 3 +Gamma-tubulin complex component protein [IPR007259] 0.7351157662623989 0.985873945119074 0.32419497387229 1.0 0.4147722694769962 2 Q9BSJ2 1 +Valine-tRNA ligase [IPR002303] 0.7301543550165333 0.9653959821600986 0.3343465131331344 1.0 0.4230786930891236 2 Q5ST30 1 +Core histone macro-H2A [IPR021171] 0.7202315325248063 0.9246471741064238 0.3551494660586503 1.0 0.4419460844451814 2 Q9P0M6 1 +Microtubule associated protein 1 [IPR026074] 0.7395854368395627 0.9080849091634694 0.3638333628397556 1.0 0.4495150451751238 3 P46821 1 +Formate-tetrahydrofolate ligase, FTHFS [IPR000559] 0.7086549062844487 0.877497237160804 0.3802166188449758 1.0 0.4643124938878485 2 Q6UB35 1 +KH domain-containing BBP-like [IPR045071] 0.7309070857457933 0.8755871771701235 0.3812544988147119 1.0 0.4648423700399058 3 Q15637,Q96PU8 2 +Histone H2A [IPR002119] 0.7204301075268795 0.8366401799038176 0.4027948533004291 1.0 0.4842962382619977 3 P16104,Q9P0M6 2 +E3 ubiquitin ligase Bre1 [IPR013956] 0.6979051819184175 0.8341431780413241 0.404200306337898 1.0 0.4853084247213892 2 O75150 1 +Peptidase, FtsH [IPR005936] 0.695700110253577 0.8253059210997422 0.4091979310762006 1.0 0.4892392325447896 2 Q9Y4W6 1 +Ribosomal protein L13 [IPR005822] 0.6948732083792666 0.8219971075503235 0.4110785431085282 1.0 0.4904311939493404 2 P40429 1 +Ergosterol biosynthesis ERG4/ERG24 [IPR001171] 0.7094017094017071 0.7960212768256032 0.4260196686636555 1.0 0.5026380019309711 3 Q9UBM7,Q14739 2 +Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672] 0.7088502894954484 0.7940013283451504 0.4271946580392898 1.0 0.5031244153231189 3 Q6UB35,P13995 2 +CPSF6/7 family [IPR034772] 0.6877067254685713 0.7934429878247938 0.4275197734529421 1.0 0.5031244153231189 2 Q8N684 1 +Ezrin/radixin/moesin [IPR011174] 0.7082988695891899 0.7919824716083408 0.4283708968355677 1.0 0.5034854886567982 3 P26038,P15311 2 +SLC12A transporter family [IPR004842] 0.6857772877618735 0.7857941378764092 0.4319881014784623 1.0 0.5070926318116468 2 P55011 1 +ThiF/MoeB/HesA family [IPR045886] 0.4417796723738137 0.7806005862246548 0.4350374468887259 1.0 0.5098095080727256 8 Q9UBT2,Q13564,Q9GZZ9,P22314 4 +Mesoderm induction early response protein/metastasis-associated protein [IPR040138] 0.6835722160970166 0.7770735564435628 0.4371153742719622 1.0 0.5111219874657171 2 O94776 1 +Ribosomal protein L11/L12 [IPR000911] 0.6788864388092775 0.7586188397498157 0.4480805994364967 1.0 0.5200433556822578 2 Q9Y3B7 1 +Cell-cycle alteration and expression-elevated protein in tumour [IPR032337] 0.6936862420733365 0.7389023423822949 0.4599662998849507 1.0 0.5296292457181486 3 Q9NQG5,Q96P16 2 +Histidine phosphatase superfamily, clade-1 [IPR013078] 0.6908450122625458 0.7286812442298185 0.4661966683244076 1.0 0.5339231343789647 3 Q96HS1 1 +HAD-superfamily hydrolase, subfamily IIA [IPR006357] 0.5695368701916338 0.697387340117663 0.4855604221568712 1.0 0.5475132756949685 4 Q96GD0 1 +DNA-directed RNA polymerase, subunit beta-prime [IPR045867] 0.6795545345457084 0.6884157094947749 0.4911910338665888 1.0 0.5509519478495489 3 O14802 1 +SURP and G-patch domain-containing protein 1/2 [IPR040169] 0.6606945975744135 0.6880441045627452 0.4914250078017912 1.0 0.5509903079628923 2 Q8IX01 1 +Hydantoinase/dihydropyrimidinase [IPR011778] 0.6601433296582186 0.6859341930193251 0.4927546069815225 1.0 0.5515909779643909 2 Q9BPU6 1 +Integrin alpha chain [IPR000413] 0.6579382579933771 0.6775125669110134 0.4980807994076306 1.0 0.5556692737944188 2 P17301 1 +NudC family [IPR037898] 0.6749379652605432 0.6721226424674308 0.5015056229682606 1.0 0.5582342975278473 3 Q8IVD9,Q9Y266 2 +HnRNP R/Q splicing factor [IPR006535] 0.6488423373759566 0.6430892931441752 0.5201661614966118 1.0 0.5712713087308101 2 O60506 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.6485667034178593 0.6420543805988471 0.5208378747500375 1.0 0.5717267019111368 2 P31689 1 +Taxilin family [IPR026183] 0.6466372657111273 0.6348239794713532 0.525543222021148 1.0 0.5747419635834197 2 Q9NUQ3 1 +P-type ATPase, subfamily IIB [IPR006408] 0.6405733186328624 0.6122630501747679 0.5403637322202779 1.0 0.5864330687959606 2 P20020 1 +Thiolase [IPR002155] 0.5054852318969566 0.6080018282469704 0.5431862613355052 1.0 0.5880041053245951 5 P24752,P42765,P55084 3 +Chaperone DnaJ [IPR012724] 0.654382287096664 0.6009189602409283 0.5478939640750622 1.0 0.5913674641416949 3 Q96EY1 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.6295479603087013 0.5719124529952209 0.5673812870021315 1.0 0.6043461782520062 2 Q9UKM9 1 +Alanine-tRNA ligase, class IIc [IPR002318] 0.6276185226019757 0.5649446017440471 0.5721114453276868 1.0 0.6082794102621957 2 Q5JTZ9 1 +Alanine-tRNA ligase, eukaryota/bacteria [IPR023033] 0.6276185226019757 0.5649446017440471 0.5721114453276868 1.0 0.6082794102621957 2 Q5JTZ9 1 +Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349] 0.6267916207276647 0.5619672223105097 0.5741383516303586 1.0 0.609500354160002 2 P27361 1 +EF-hand domain-containing protein D1/2 [IPR040365] 0.626515986769561 0.5609759508755314 0.5748139318085561 1.0 0.6099841914985633 2 Q96C19 1 +Lupus La protein [IPR002344] 0.6259647188533648 0.5589951982556538 0.5761649972496588 1.0 0.6111842000641449 2 P05455 1 +Kinesin light chain [IPR002151] 0.6240352811466282 0.5520814965128461 0.5808925186347513 1.0 0.6159635992401357 2 Q07866 1 +TAF15/EWS/TLS family [IPR034870] 0.6385442514474742 0.5477333582460001 0.5838750034309985 1.0 0.6186533541508289 3 Q92804,Q01844 2 +Pyrroline-5-carboxylate reductase [IPR000304] 0.6356423971877638 0.5381638093753198 0.5904639628867439 1.0 0.6251573815378536 3 Q96C36 1 +Prolyl 4-hydroxylase [IPR045054] 0.6116317530319639 0.508366744843589 0.6111961700020965 1.0 0.6453840836209352 2 P13674 1 +Aspartate/other aminotransferase [IPR000796] 0.6105292171995493 0.5045445617652295 0.61387875606005 1.0 0.6479701590211635 2 P00505 1 +Sorting nexin-5/6/32 [IPR014637] 0.6074972436604094 0.4940892463664149 0.6212431521005941 1.0 0.6549961045133543 2 Q9UNH7 1 +Tyrosine-tRNA ligase [IPR002307] 0.5970231532524706 0.4586211199892397 0.6465062674364093 1.0 0.6803393599302373 2 P54577 1 +Flotillin family [IPR027705] 0.595920617420056 0.4549482730807851 0.6491464528808208 1.0 0.6828587591904011 2 O75955 1 +C-terminal binding protein [IPR043322] 0.5953693495038488 0.4531162981403941 0.6504650000031078 1.0 0.6839865005716651 2 Q13363 1 +Alpha-D-phosphohexomutase superfamily [IPR005841] 0.5826901874310808 0.4118248110816319 0.6804678344352755 1.0 0.7131035651653661 2 Q96G03 1 +Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423] 0.3523888428610937 0.3887484869385356 0.6974622106233865 1.0 0.7300858674009422 9 P50991,P10809,P40227,P78371,P48643,P49368,P17987,P50990 8 +Coronin [IPR015505] 0.5866662632287238 0.3862794329995748 0.6992897308006834 1.0 0.7317228517993576 3 Q9ULV4 1 +ATP:guanido phosphotransferase [IPR000749] 0.5722160970231421 0.3789948062627716 0.7046917206616017 1.0 0.7368197154619234 2 P12532 1 +La domain containing protein [IPR045180] 0.4384570577704356 0.3572049003713939 0.7209384176161242 1.0 0.7529560063548154 5 Q6PKG0 1 +Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998] 0.3522915516289324 0.3506509326588118 0.7258502409336216 1.0 0.7572309844326316 8 P50991,P40227,P78371,P48643,P49368,P17987,P50990 7 +Initiation factor 4G [IPR045208] 0.5701681830714052 0.3398386567665458 0.7339780347065283 1.0 0.7642735633435708 3 Q04637,O43432 2 +SH3-binding, glutamic acid-rich protein [IPR006993] 0.5407938257993262 0.2881808546199929 0.7732083032238961 1.0 0.8033145044725989 2 Q9UJC5 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.5461814171491554 0.2772835243719631 0.7815624094139284 1.0 0.8107796957471594 3 P51114,Q06787 2 +Molecular chaperone regulator BAG [IPR039773] 0.5307416597739139 0.2403829013708272 0.810033432383825 1.0 0.8381218399944498 3 O95429,O95817 2 +Vesicle-associated membrane-protein-associated protein [IPR016763] 0.5033076074972301 0.1966944526572874 0.8440666514325699 1.0 0.8700909946973928 2 Q9P0L0 1 +Vinculin/alpha-catenin [IPR006077] 0.509181110627391 0.1935622330530516 0.8465186725025378 1.0 0.872294584550517 3 P18206 1 +Ribosomal protein L1/ribosomal biogenesis protein [IPR028364] 0.4929693961951982 0.1621152778610257 0.8712150753488062 1.0 0.8940909149751985 3 Q9BYD6,O76021 2 +Syntaxin [IPR045242] 0.3153541898161544 0.1549777427615138 0.8768388639924356 1.0 0.8995297033563803 7 O43752 1 +Casein Kinase 2, subunit alpha [IPR045216] 0.4691289966923775 0.1307209478029803 0.8959960605888901 1.0 0.9174867410089188 2 P68400 1 +Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257] 0.4481808158765014 0.098635747803831 0.9214274857628127 1.0 0.9410972664673558 2 P10515 1 +Inosine-5'-monophosphate dehydrogenase [IPR005990] 0.436879823594252 0.0838787060090152 0.9331528700302772 1.0 0.9527223010794772 2 P20839 1 +2-oxoglutarate dehydrogenase E1 component [IPR011603] 0.4299889746416646 0.0757249217977878 0.9396379481892048 1.0 0.9572302886288704 2 Q02218 1 +Glycogen/starch/alpha-glucan phosphorylase [IPR011833] 0.42282249173097 0.0679010457065467 0.9458644063227912 1.0 0.9619206513466724 2 P06737 1 +Glycosyl transferase, family 35 [IPR000811] 0.42282249173097 0.0679010457065467 0.9458644063227912 1.0 0.9619206513466724 2 P06737 1 +Ribosomal protein S5 [IPR000851] 0.4222712238147619 0.067326302426708 0.9463219380815912 1.0 0.9619206513466724 2 P82675 1 +Ribonucleotide reductase small subunit family [IPR000358] 0.41179713340682 0.0571188673864634 0.9544505069578142 1.0 0.968763773521556 2 Q7LG56 1 +Ribonucleotide reductase small subunit [IPR033909] 0.41179713340682 0.0571188673864634 0.9544505069578142 1.0 0.968763773521556 2 Q7LG56 1 +Dynamin [IPR022812] 0.3315263812764862 0.0539017758706676 0.9570134217845184 1.0 0.9703315547301492 4 P50570 1 +E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322] 0.3969128996692261 0.0448265250586355 0.9642455823999194 1.0 0.9765625880145168 2 Q9ULT8 1 +ADP-ribosylation factor-like protein 2/3 [IPR044612] 0.3875413450937081 0.0383178717709924 0.9694342416372156 1.0 0.9809565401794876 2 P36405 1 +Lon protease, bacterial/eukaryotic-type [IPR004815] 0.3864388092612875 0.0376106621673859 0.9699981067576626 1.0 0.9809565401794876 2 P36776 1 +Lon protease [IPR027065] 0.3864388092612875 0.0376106621673859 0.9699981067576626 1.0 0.9809565401794876 2 P36776 1 +Glutamyl/glutaminyl-tRNA synthetase [IPR000924] 0.3884753239591898 0.0359328256056371 0.9713359217124972 1.0 0.98159402139555 3 Q5JPH6,P07814 2 +Tumour protein D52 [IPR007327] 0.3682469680264499 0.0275750650383273 0.9780010693180364 1.0 0.9867936073714944 2 P55327 1 +Oxysterol-binding protein [IPR000648] 0.2579062764312614 0.027251454495461 0.9782591761726058 1.0 0.9867936073714944 6 P22059 1 +Ribosomal protein S15 [IPR000589] 0.3569459757442002 0.0227414076493934 0.9818565458390388 1.0 0.9897028386136332 2 P62277 1 +Tropomyosin [IPR000533] 0.3556658395368023 0.01934225267607 0.9845680774634686 1.0 0.9914290116187124 3 P09493,P67936 2 +Ribosomal protein L3 [IPR000597] 0.3183572216096931 0.0124190831882696 0.9900912599755604 1.0 0.9946558620495096 2 P39023 1 +Peptidyl-tRNA hydrolase, PTH2 [IPR002833] 0.3133958103638269 0.0116239691543292 0.9907256233307804 1.0 0.9946558620495096 2 Q6GMV3 1 +ATP-dependent RNA helicase Ski2-like [IPR016438] 0.3106394707827907 0.0112223160487477 0.9910460752320926 1.0 0.9946558620495096 2 Q15477 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.2651476671811309 0.0101405518444558 0.9919091489102958 1.0 0.9946558620495096 4 Q9H0U9 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5982f949543a1f59e964afb0e43d2ee2a1620e8f --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 [IPR039210]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome non-ATPase regulatory subunit 9 [IPR035269]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S24, mitochondrial [IPR026146]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S26 [IPR026140]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-keto-steroid reductase [IPR042829]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "4-aminobutyrate aminotransferase, eukaryotic [IPR004631]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5'-deoxynucleotidase YfbR/HDDC2 [IPR039356]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABI family [IPR028457]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6 [IPR041839]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 6-interacting protein 6 [IPR029383]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP synthase-coupling factor 6, mitochondrial [IPR008387]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP12, ATP synthase F1-assembly protein [IPR011419]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Abl interactor 1 [IPR028456]", "Abr/Bcr [IPR037769]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Actin-related protein 6 [IPR030054]", "Actin-related protein 8/Plant actin-related protein 9 [IPR027668]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activating signal cointegrator 1-like [IPR039128]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA thioesterase, long chain [IPR016662]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase [IPR011408]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-catulin 1 [IPR030045]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid beta precursor protein binding family B member 1/2/3 [IPR039576]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A3 [IPR002390]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Apolipoprotein C-I [IPR006781]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAK [IPR026308]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Armadillo-like helical domain-containing protein 3-like [IPR039868]", "Arrestin [IPR000698]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arsenite methyltransferase-like [IPR026669]", "Arv1 protein [IPR007290]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atg6/Beclin [IPR007243]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 5 [IPR007239]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BEN domain-containing protein 3 [IPR033583]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRO1 domain-containing protein BROX [IPR038898]", "BTB-kelch protein [IPR017096]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Bardet-Biedl syndrome 4 protein [IPR028786]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beclin-1 [IPR032913]", "Bet3 family [IPR016721]", "Beta tubulin [IPR002453]", "Beta-1,4-galactosyltransferase [IPR003859]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "C2 domain-containing protein 5 [IPR038983]", "C2H2-type Zinc finger protein, YY1-like [IPR017114]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT complex, subunit 3/ 5 [IPR012270]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 11 [IPR019312]", "CCR4-NOT transcription complex subunit 4 [IPR039780]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDC50/LEM3 family [IPR005045]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGI121/TPRKB [IPR013926]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 2 [IPR037354]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome complex subunit 7B [IPR027530]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPI-17 [IPR008025]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calmodulin-regulated spectrin-associated protein [IPR032940]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calsyntenin [IPR026914]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle control protein 50A [IPR030351]", "Cell division cycle protein 123 [IPR009772]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-K [IPR020993]", "Centromere protein H [IPR040034]", "Centromere protein P [IPR027801]", "Centromere protein U [IPR025214]", "Centrosomal protein of 131kDa [IPR030465]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 290kDa [IPR026201]", "Centrosomal protein of 44kDa [IPR033603]", "Ceramide glucosyltransferase [IPR025993]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Ceroid-lipofuscinosis neuronal protein 6 [IPR029255]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-6 [IPR002248]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Choline/ethanolamine phosphotransferase [IPR014472]", "Chondroitin N-acetylgalactosaminyltransferase [IPR008428]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromatin modification-related protein Eaf6 [IPR015418]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Clusterin [IPR016016]", "Clusterin-like [IPR000753]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 127 [IPR034607]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 43 [IPR037666]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coiled-coil domain-containing protein R3HC1/R3HCL [IPR039884]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Conserved oligomeric Golgi complex subunit 5 [IPR019465]", "Conserved oligomeric Golgi complex subunit 6 [IPR010490]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex subunit 8 [IPR007255]", "Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae [IPR016632]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine oxygenase/2-aminoethanethiol dioxygenase [IPR012864]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein COX14 [IPR029208]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit I [IPR000883]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic protein NCK [IPR017304]", "Cytoplasmic protein NCK1 [IPR028526]", "Cytoplasmic tRNA 2-thiolation protein 2 [IPR019407]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 8-like [IPR045151]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed DNA-polymerase, family A, mitochondria [IPR002297]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase III subunit Rpc5 [IPR006886]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxynucleoside kinase [IPR002624]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone kinase [IPR012734]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylallyltransferase [IPR039657]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphosphomevalonate decarboxylase [IPR029765]", "Diphosphomevalonate/phosphomevalonate decarboxylase [IPR005935]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Dishevelled family [IPR008339]", "Dishevelled-2 [IPR008341]", "Dishevelled-related protein [IPR015506]", "Disks large 1-like [IPR016313]", "Divalent ion tolerance protein, CutA [IPR004323]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase PIAS2 [IPR027228]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase Praja-2 [IPR030639]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase RNF213 [IPR031248]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-binding protein 1 [IPR029944]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "ETS family [IPR046328]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosome-associated-trafficking regulator 1 [IPR026757]", "Endothelial protein C receptor [IPR015669]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-2 [IPR027673]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "F-box-like/WD repeat-containing protein Ebi-like [IPR045183]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM91 [IPR039199]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FHF complex subunit HOOK interacting protein [IPR019384]", "FUN14 [IPR007014]", "Fanconi anemia group G protein [IPR039684]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Formin-binding protein 1 [IPR028532]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "Fyv10 family [IPR045098]", "G patch domain-containing protein 11 [IPR039249]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase 2-like [IPR045130]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GDP-mannose 4,6-dehydratase [IPR006368]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOLM1/CASC4 family [IPR026139]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPCR-associated sorting protein [IPR043374]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI-anchor transamidase [IPR028361]", "GPN-loop GTPase 1 [IPR030230]", "GPN-loop GTPase [IPR004130]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP cyclohydrolase 1 type 2/Nif3 [IPR002678]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "GTP-binding protein, ribosome biogenesis [IPR019991]", "GTP-binding protein, ribosome biogenesis, YsxC [IPR019987]", "GTPase, MTG1 [IPR016478]", "Galactokinase [IPR000705]", "Galanin precursor [IPR008175]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma tubulin [IPR002454]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "Gemini of Cajal bodies-associated protein 8 [IPR034754]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Geranylgeranyl transferase type-2 subunit beta [IPR026873]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-rich protein 1 [IPR026719]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutaminase [IPR015868]", "Glutamine-dependent NAD(+) synthetase [IPR014445]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, alpha class [IPR003080]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl hydrolase family 99 [IPR026071]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 43 [IPR005027]", "Glycosyl transferase, family 8 [IPR002495]", "Glycosyltransferase 61 [IPR007657]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi membrane protein 1 [IPR026143]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanidinoacetate N-methyltransferase [IPR016550]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HCLS1-binding protein 3 [IPR039701]", "HEXIM [IPR024872]", "HMG-CoA lyase [IPR043594]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase SMUBP-2/Hcs1-like [IPR004483]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H3/CENP-A [IPR000164]", "Histone H4 [IPR001951]", "Histone PARylation factor 1 [IPR019361]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone acetyltransferases subunit 3 [IPR019340]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP30/SAP30-like [IPR024145]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone transcription regulator 3/CABIN1 [IPR033053]", "Histone-lysine N-methyltransferase EZH1/2-like [IPR045318]", "Histone-lysine N-methyltransferase EZH1/EZH2 [IPR021654]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin-interacting protein 1 [IPR030554]", "Huntingtin-interacting protein 1-related protein [IPR030555]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "Hypoxia-inducible factor 1-alpha inhibitor [IPR027445]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "IPP transferase [IPR018022]", "IQ calmodulin-binding motif-containing protein 1 [IPR028765]", "Immunity-related GTPase family Q protein [IPR040070]", "Impact family [IPR023582]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Innexin [IPR000990]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integral membrane protein SYS1 [IPR016973]", "Integral membrane protein SYS1-related [IPR019185]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 2 [IPR029321]", "Integrator complex subunit 2, metazoa [IPR026236]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 9 [IPR027074]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intermembrane space protein MIX23 [IPR019171]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intraflagellar transport protein 52 homolog [IPR039975]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isoamyl acetate-hydrolyzing esterase Iah1-like [IPR045136]", "Isochorismatase domain-containing protein 2 [IPR040318]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "Junctional adhesion molecule C [IPR042974]", "K/Cl co-transporter 4 [IPR030354]", "K/Cl co-transporter [IPR000076]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Katanin p60 subunit A1 [IPR028596]", "Kelch-like ECH-associated protein 1 [IPR030563]", "Keratin, type I [IPR002957]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "L-type amino acid transporter [IPR004760]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LMBR1-like membrane protein [IPR006876]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Learning associated protein 18-like [IPR018784]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper putative tumor suppressor [IPR045329]", "Leucine zipper putative tumour suppressor 2 [IPR028597]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte elastase inhibitor (serpin B1) [IPR015557]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Liprin-alpha-1 [IPR030438]", "Lon protease [IPR027065]", "Lon protease homologue 2, peroxisomal [IPR027501]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosomal-associated transmembrane protein 4/5 [IPR004687]", "Lysosomal-associated transmembrane protein, 4A/5 [IPR018396]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase phosphoprotein 6 [IPR019324]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MOB kinase activator family [IPR005301]", "MORF4 family-associated protein 1 [IPR029254]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter MRS2-like [IPR039204]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membralin [IPR019144]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase Ppm1/Ppm2/Tcmp [IPR007213]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microsomal glutathione S-transferase 1-like [IPR040162]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein Mtm1-like [IPR045315]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial dynamics protein MID49/MID51 [IPR045909]", "Mitochondrial fission regulator 1 [IPR007972]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase kinase kinase 7 [IPR017421]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitoguardin [IPR019392]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Molybdenum cofactor sulfurase [IPR028886]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylgalactosamine-6-sulfatase [IPR035626]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyl phosphatidylinositol deacetylase-related [IPR003737]", "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [IPR039516]", "N-acetyltransferase Ard1-like [IPR045047]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-lysine methyltransferase FAM173A/B [IPR026170]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(+) synthetase [IPR003694]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-plastoquinone oxidoreductase, chain 5 subgroup [IPR018393]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain 5-like [IPR003945]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B inhibitor-like protein 1 [IPR038753]", "NIF3-like protein 1, animal [IPR017222]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "NUDE family [IPR033494]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neurogenic locus Notch 2 [IPR022336]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Neuroplastin [IPR027112]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Notch [IPR008297]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear RNA-splicing-associated protein, SR-25 [IPR019532]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "Occludin [IPR002958]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PAX family [IPR043565]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein 8 [IPR039275]", "PDZ domain-containing protein GIPC1/2/3 [IPR017379]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Palmitoyltransferase ZDHHC13 [IPR030290]", "Pannexin [IPR039099]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Parvin [IPR028433]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1A, Tysnd1 [IPR017345]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal membrane protein 4 [IPR019531]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisomal/glyoxysomal leader peptide-processing protease [IPR039245]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polycomb protein EED [IPR037352]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Progesterone-induced-blocking factor 1 [IPR026205]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein C10 [IPR026317]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein FMC1 homologue [IPR037667]", "Protein FRG1 [IPR010414]", "Protein Fyv10/E3 ubiquitin-protein transferase MAEA [IPR027714]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LCHN/Anr2 [IPR018626]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NCBP2AS2 [IPR042407]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein OS-9-like [IPR045149]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sec13 [IPR037596]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1387 [IPR009816]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein suppressor of sable-like [IPR045124]", "Protein translocase SEC61 complex, gamma subunit [IPR008158]", "Protein translocase complex, SecE/Sec61-gamma subunit [IPR001901]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein wntless [IPR009551]", "Protein-L-histidine N-pros-methyltransferase [IPR007884]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxamine 5'-phosphate oxidase [IPR000659]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "Queuosine salvage protein family [IPR019438]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RFT1 [IPR007594]", "RFX-like DNA-binding protein [IPR039779]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-2 [IPR033087]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit Pop5/Rpp14/Rnp2-like [IPR002759]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab11-family interacting protein class I [IPR037789]", "Rab12 [IPR041830]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab35 [IPR041815]", "Rab39 [IPR041818]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Refilin family [IPR028215]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Reticulon-4-interacting protein 1 [IPR037397]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho GTPase-activating protein 10 [IPR035486]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Riboflavin kinase [IPR023468]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease H2, subunit C [IPR013924]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease P protein subunit Rpp29/RNP1 [IPR002730]", "Ribonuclease P protein subunit Rpp40 [IPR013893]", "Ribonuclease P/MRP subunit Rpp29 [IPR016848]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27/L41, mitochondrial [IPR019189]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S27/S33, mitochondrial [IPR013219]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome biogenesis protein Slx9-like [IPR028160]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLAIN motif-containing protein [IPR026179]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SSNA1 family [IPR033362]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saf4/Yju2 protein [IPR007590]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 3 [IPR008114]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 2-like [IPR034893]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase RAC alpha [IPR039027]", "Serine/threonine-protein kinase SMG1 [IPR031559]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit [IPR037981]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Short coiled-coil protein [IPR019357]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Slowmo/Ups family [IPR037365]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small kinetochore-associated protein [IPR033373]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Snf8/Vps36 family [IPR040608]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 25 member 44 [IPR042164]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-4 [IPR034783]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-8/Mvp1 [IPR028662]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spastin [IPR017179]", "Spastin, chordate [IPR035106]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermatogenesis-defective protein 39 [IPR040057]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle assembly checkpoint component Mad1 [IPR008672]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor Yju2 [IPR043701]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Sulphide quinone-reductase [IPR015904]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syndetin [IPR040047]", "Syntaxin [IPR045242]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex 11 [IPR008862]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TATA-Box binding protein-like [IPR015445]", "TATA-box binding protein [IPR000814]", "TB2/DP1/HVA22-related protein [IPR004345]", "TCF25/Rqc1 [IPR006994]", "TE2IP/Rap1 [IPR039595]", "TFIIH subunit Tfb1/GTF2H1 [IPR027079]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM115/Pdh1/Rbl19 [IPR013861]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM206 protein [IPR029366]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "Tankyrase 1-binding protein-like [IPR040006]", "Tapasin [IPR008056]", "Target of Myb protein 1 [IPR014645]", "Target of Myb1-like 2 [IPR027429]", "TatD family [IPR001130]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Tectonic [IPR040354]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 15 [IPR042418]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor TFIIH subunit p52/Tfb2 [IPR004598]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor cyclic AMP-dependent, CRE-BP1-type [IPR016378]", "Transcription factor, GA-binding, alpha subunit [IPR016312]", "Transcription factor, enhancer of yellow 2 [IPR018783]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TFIID, 23-30kDa subunit [IPR003923]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription termination factor, mitochondrial/chloroplastic [IPR003690]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery associated TMA7 [IPR015157]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Translocon-associated protein subunit gamma [IPR009779]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 131-like [IPR039877]", "Transmembrane protein 161A/B [IPR019395]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Transposase, L1 [IPR004244]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumor necrosis factor alpha-induced protein 8-like [IPR008477]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U4/U6.U5 small nuclear ribonucleoprotein component Snu23 [IPR040107]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm1/8 [IPR044642]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronic acid decarboxylase [IPR044516]", "UDP-glucuronosyl/UDP-glucosyltransferase [IPR002213]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "UbiA prenyltransferase domain containing protein 1 [IPR026046]", "UbiA prenyltransferase family [IPR000537]", "Ubiquilin-1/2 [IPR028430]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquinone biosynthesis O-methyltransferase [IPR010233]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Ubiquitously expressed transcript protein UXT [IPR003994]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0640 [IPR028183]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar ATPase assembly integral membrane protein Vma21 [IPR019013]", "Vacuolar fusion protein Mon1 [IPR004353]", "Vacuolar import/degradation protein Vid24 [IPR018618]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting protein 36 [IPR037855]", "Vacuolar protein sorting-associated Vps28 [IPR007143]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vinexin [IPR028510]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps72/YL1 family [IPR008895]", "WASH complex subunit 3 [IPR019309]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 89 [IPR039328]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YIP1 family member 3 [IPR026637]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger HIT domain-containing protein 2 [IPR039646]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc finger protein-like 1 [IPR039043]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA capping enzyme, bifunctional [IPR017074]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA splicing factor Cwf18-like [IPR013169]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 and DNA damage-regulated protein 1 [IPR030482]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "siRNA-mediated silencing protein NRDE-2 [IPR013633]", "tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 [IPR014816]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA isopentenyltransferase, eukaryotes [IPR030666]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB [IPR006463]", "tRNA-guanine transglycosylase [IPR004803]", "tRNA-specific 2-thiouridylase [IPR004506]", "von Willebrand factor A domain-containing protein 8 [IPR039891]"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACAD10", "ACADM", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANKLE2", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEX1", "API5", "APLP2", "APOC1", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP10", "ARHGAP5", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC6", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD3A", "ATAD3B", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN2L", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRI3BP", "BRIP1", "BRIX1", "BROX", "BSG", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C10orf76", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD2", "C2CD2L", "C2CD5", "C2orf49", "C3orf58", "C5orf24", "C5orf51", "C8orf33", "C9orf64", "CAB39", "CABIN1", "CAD", "CALD1", "CALR", "CALU", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CAST", "CBR1", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCDC97", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC20", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CELF2", "CENPB", "CENPH", "CENPK", "CENPP", "CENPU", "CEP131", "CEP170", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CIAPIN1", "CIP2A", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COIL", "COLGALT1", "COMMD2", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EFHD1", "EFHD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERICH1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESF1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM129B", "FAM160B2", "FAM162A", "FAM173A", "FAM177A1", "FAM207A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNBP1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC1", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAL", "GALK1", "GALM", "GALNS", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GEMIN4", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GID4", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GM2A", "GMDS", "GMFB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPATCH11", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPT2", "GPX8", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDHD2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IGHMBP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS14", "INTS2", "INTS3", "INTS5", "INTS9", "IPO4", "IPO5", "IQCB1", "IRGQ", "IRS4", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "JAGN1", "JAM3", "JPT2", "JUP", "KARS", "KATNA1", "KDELR1", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KNSTRN", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMBRD1", "LMF2", "LNPEP", "LONP1", "LONP2", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LSM12", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTERF3", "MTFP1", "MTFR1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTR", "MTX1", "MTX2", "MVD", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA16", "NAA40", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NFKBIL1", "NFS1", "NHP2", "NIF3L1", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRDE2", "NRM", "NRP1", "NSA2", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARVA", "PATL1", "PAWR", "PAX6", "PAXBP1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDP1", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD8", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PJA2", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CC", "PPP1R12A", "PPP1R14B", "PPP2R1A", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PXMP4", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "R3HCC1", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM45", "RBM5", "RBM6", "RBM8A", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFK", "RFLNB", "RFT1", "RFX1", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX2", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCLY", "SCO1", "SCO2", "SCOC", "SCPEP1", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SLAIN2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG1", "SMG8", "SMIM12", "SMIM4", "SMPD4", "SMS", "SMU1", "SMYD3", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SPAG9", "SPART", "SPAST", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPNS1", "SPPL2A", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SQOR", "SRFBP1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF2", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STARD3", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYS1", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAPBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBPL1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TCP11L1", "TCTN3", "TECR", "TEDC1", "TEFM", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TLE3", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM131", "TMEM14C", "TMEM161A", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMX2", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO2", "TOE1", "TOM1L2", "TOMM20", "TOMM22", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPRKB", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TSPYL1", "TSR1", "TSTA3", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", 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b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ba88a96a6f9281dc7cc6ea7ba12e2d53188d3123 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,29 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 76 134 5.133470971505917 2.844469195478702e-07 41.78155339805825 126.65533980582524 0.1165973051667422 0.543214063567699 13.579176287791377 6.87987395678373 1.6323826073741117 0.3875195330163939 1.0 0.0762657298482616 2.739192600159672e-05 2.1685329965033505e-08 2.8345143604883364e-15 +RNA-binding domain superfamily [IPR035979] 77 135 5.045648427399872 4.51985852522157e-07 42.40291262135922 128.71601941747574 0.0615554024640467 0.5527296641044032 14.098054374547743 6.713949807605091 1.6556654950344032 0.3906506493803742 1.0 0.0745079706834489 0.0001463467420772 4.327019780893334e-07 5.531430588194543e-14 +Zinc finger C2H2 superfamily [IPR036236] 17 26 3.514932827342743 0.0004398652333572 8.764563106796116 19.92718446601942 -0.8135859964419523 0.4297460862194966 4.192041298224235 4.215037669844161 0.967607858426508 0.3252416638393141 1.0 0.5921930770843471 0.7606838709528396 0.9335608951489934 0.9952460847978176 +K Homology domain, type 1 superfamily [IPR036612] 9 27 3.3146974262269 0.000917423697742 8.754854368932039 25.199029126213592 0.3274932579192284 0.6117373027860772 4.9138797603502615 1.673377791223898 0.8713427238211133 0.3293224632085303 1.0 1.0 1.0 0.6113547810413322 0.0021190704165708 +Zinc finger, FYVE/PHD-type [IPR011011] 12 28 3.081976141933348 0.0020563131791877 10.54611650485437 25.23543689320388 -0.824626170227196 0.4352381619302825 5.555134899659675 5.395108046048921 1.1543966185083765 0.3445762253615666 1.0 1.0 0.095403296278499 0.5147898021560477 0.0440141365182753 +Kinesin motor domain superfamily [IPR036961] 15 21 3.049409176929999 0.002292919511035 8.776699029126213 20.87864077669903 -0.4632203456084914 0.5505339958906699 4.354290460485026 3.3217187762121245 0.9197693790875688 0.3299373754272141 1.0 0.2486824788491954 0.4363210249842685 0.1696751373461712 0.0219335059982234 +Zinc finger, RING/FYVE/PHD-type [IPR013083] 23 65 3.03147339658833 0.002433633648341 17.553398058252426 55.0752427184466 -0.6243042190077778 0.4937537456818005 8.21817563594848 12.873607708273726 1.0759750502816785 0.3411432431052099 1.0 0.2028209372426047 0.0360021910350022 0.5179703167917804 0.2846911673790999 +SAP domain superfamily [IPR036361] 5 12 2.7415569957005355 0.0061148750934871 5.439320388349515 11.716019417475728 -0.8580415992548751 0.4265542426017202 2.588005853047778 1.3704352931922197 0.8961724361175389 0.3193174469011388 1.0 0.0051137089586154 0.0193632099375005 0.0018222556728696 0.0004973671187583 +ENTH/VHS [IPR008942] 5 16 2.703352897799188 0.0068643824336334 5.075242718446602 12.019417475728156 -0.4557278107356008 0.5677325572133788 2.839846278029029 2.112057766771552 0.7309452661481495 0.2963813178245082 1.0 1.0 0.2263045436956677 0.4759945765538561 0.0012998754323988 +SH3-like domain superfamily [IPR036028] 18 37 2.625571659407544 0.0086503598403873 7.827669902912621 30.75485436893204 0.1458604778244563 0.6315015103936021 4.313774664050148 5.335410260579265 0.8529860578790123 0.3168420523015797 1.0 0.502402347983314 0.7532548236979018 0.6764752417377177 0.5354046724765329 +PH-like domain superfamily [IPR011993] 33 64 2.6217190385790587 0.008748752259317 16.538834951456312 55.366504854368934 -0.1721757009659374 0.6272733937475546 8.168489456557142 10.439569255029584 0.8639046053288412 0.3178368882722004 1.0 0.7956971423996854 0.9585917694515896 0.9557091627869422 0.9756686524260896 +Cyclophilin-like domain superfamily [IPR029000] 6 15 2.489095210451932 0.0128068663722815 5.468446601941747 11.41747572815534 -0.7281726207623201 0.4388303162721199 2.458682754632111 2.1202869921363305 0.8994681406076788 0.3140809133543877 1.0 1.0 1.0 0.0008233445075453 0.0013613651941044 +Ribosomal protein L2, domain 2 [IPR014722] 5 13 2.45638991272049 0.0140340793818416 5.737864077669903 11.25 -0.6609982231548526 0.3931826402266836 2.497420669599456 1.4740884957165508 1.0649776696651303 0.3158800401167336 1.0 0.0802348466038066 0.1543818096433915 0.0006528604561368 0.0001016217979366 +PDZ superfamily [IPR036034] 12 30 2.4295727780381853 0.0151166296508662 5.973300970873787 22.946601941747577 -0.0368180881644222 0.6322040531585648 3.566533463778447 4.484824801677742 0.77383334979081 0.2894243816074855 1.0 0.4018208263035032 0.6430935383041047 0.4713767182287368 0.2437596313950178 +Bromodomain-like superfamily [IPR036427] 8 15 2.428924766026977 0.0151436744080457 6.701456310679611 14.70388349514563 -0.7275720657501807 0.423777584223884 3.7144035854581094 2.745638105757174 1.0685004900160548 0.3302269671896153 1.0 0.1665759675679584 0.3060304729743218 0.6015494217836266 0.2688137047180795 +BRCT domain superfamily [IPR036420] 7 12 2.4122848103739822 0.0158528924309724 6.468446601941747 12.611650485436892 -0.7681897033637983 0.4284672674601988 3.082439223656648 1.810074341168897 0.9594470361338024 0.3316037565957767 1.0 0.1114073342812727 0.2108642126213972 0.0201545454959308 0.0053032680205866 +WW domain superfamily [IPR036020] 5 11 2.365910499291356 0.0179857918364692 3.405339805825242 9.919902912621358 -0.0858555958656287 0.5637278068566357 2.2797697531221104 2.5468221184832287 0.892206572514041 0.3006643647028539 1.0 1.0 0.3196260593385788 0.6209197844592236 0.0396063215160503 +SMAD/FHA domain superfamily [IPR008984] 6 9 2.317386368270568 0.0204826942464164 4.643203883495145 10.405339805825244 -0.6405419363748494 0.4498717461642587 2.4939494601711223 2.490422553741129 0.9762664153923096 0.3240990815654961 1.0 0.0195557545343205 0.0690620672163432 0.0926724515796587 0.0614446561434308 +Translation protein SH3-like domain superfamily [IPR008991] 7 11 2.222495383286142 0.0262498456884343 5.533980582524272 10.04126213592233 -0.6036748352654394 0.3877498786779733 2.367110950515448 0.8189185143996353 1.121702761763535 0.314654675983089 1.0 0.0619434524836269 0.1203280145079081 0.0034718672031755 0.0002504856541451 +Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047] 6 9 2.1536067223765487 0.0312710266453728 5.548543689320389 8.803398058252426 -0.8922046271995788 0.394792767104068 2.3596677435057947 0.4753007293253404 0.8115077321281104 0.3120243665408555 1.0 1.0 1.0 0.2390677645130265 0.0974859568290139 +Heat shock protein 70kD, C-terminal domain superfamily [IPR029048] 6 8 2.0848045359157004 0.0370870468249786 5.150485436893204 7.851941747572815 -0.9096859308508656 0.3788702944011907 2.0905879595889303 0.4001469590533762 0.7997574326580008 0.299141873840032 1.0 1.0 1.0 0.2390677645130265 0.0974859568290139 +High mobility group box domain superfamily [IPR036910] 9 13 2.068273871834669 0.0386142772412956 4.157766990291262 11.771844660194176 -0.3083045053652034 0.5274688694397729 2.2794699741786917 1.318790080657425 0.909943997715923 0.3118324222229552 1.0 0.1624541869963563 0.299132167535026 0.0574660247750297 0.0962848984941054 +Dbl homology (DH) domain superfamily [IPR035899] 5 7 2.064065118938314 0.0390115426237225 2.1650485436893203 4.970873786407767 -0.2603834385846391 0.4983949433662193 1.675622402135014 2.7000766284689237 1.1060587808067857 0.3262483259439779 1.0 0.2336798458054532 0.4135270958140081 0.7392235469698557 0.7472648051064422 +CH domain superfamily [IPR036872] 11 30 2.04588991540938 0.0407672027568648 8.504854368932039 25.138349514563107 -0.7164062756232187 0.4508784831562523 4.107473147618039 3.395140043749966 1.1410234625396227 0.3491218583197355 1.0 1.0 1.0 0.2262454833872124 0.0438235854673598 +TFIIS/LEDGF domain superfamily [IPR035441] 3 6 2.040346426419786 0.0413158337899659 2.4344660194174756 5.815533980582524 -0.1307355293014001 0.5401750565809014 1.586678908154761 0.9003513102423012 0.9084537128914976 0.2929339527023612 1.0 1.0 0.0938999510605359 0.2199219252501269 0.0009257875785001 +UBA-like superfamily [IPR009060] 5 24 2.031403935890539 0.042214035497015 6.405339805825243 20.509708737864077 0.0100215425707711 0.6488905857064259 3.444887957520797 3.3096509235196874 0.7601138763569592 0.2908395897865147 1.0 1.0 0.3776146865857887 0.1129146346742184 0.0281454476703931 +Chromo-like domain superfamily [IPR016197] 7 9 2.017578788341435 0.0436351478414402 3.546116504854369 8.487864077669903 -0.1538801288777041 0.5547248899434332 2.0914317727846217 1.7878631550364168 0.8669578984342349 0.3013647607340537 1.0 0.1244478155008913 0.0285062952815799 0.1410845222447507 0.1423023069394473 +Zinc finger, RanBP2-type superfamily [IPR036443] 2 8 1.9832608554247275 0.0473382994441096 3.2742718446601944 8.616504854368932 0.6239078002715212 0.4100405386528319 1.463145369641179 0.7330740021954685 1.0299872364022182 0.3121093098016552 1.0 0.0981765691424607 0.0177148463510605 0.0927037920539492 0.0798154053066686 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ad843cb88ec832c1a469e85ef1f22965d2d02500 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 1020, + "title": "Average number of proteins per term", + "value": 5.091176470588235 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..be8313526c69cec01aec85bf74d882c38f4da848 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dda0dd5c45704a23f0c6caa4eee97f6f280ade9b --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,191 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 0.5893664652589987 5.133470971505917 2.844469195478702e-07 0.0002900938138542 0.0002305127847868 134 Q13283,Q8IXT5,Q9NWH9,Q9Y6M1,Q9UKM9,Q14151,O95319,P38159,P98179,Q96E39,Q9Y3B4,P09012,Q9NZI8,P78332,Q15233,P26599,Q13243,P52272,Q8IY67,Q5T8P6,Q14966,Q9GZT3,Q9Y2U8,P98175,Q9NTZ6,Q86V81,Q9NW13,P08579,O95628,Q01085,Q01844,O95104,P23588,Q8WUA2,P23246,Q96T37,Q08170,P08621,Q9UKV3,Q96I25,P19338,Q8WXF1,Q9BTD8,P62750,Q76FK4,Q9BY77,Q15056,Q13151,Q9NW64,Q9H501,O75821,Q13310,Q9Y4C8,Q8NFH5,P05455,Q14498,Q15424,P11940,Q96PK6,Q12849,Q15287,P18615,Q01130,P43243,Q9P2N5,O75494,P49756,Q9BZI7,Q9UN86,P42696,Q05519,P51991,Q53F19,P33240,P84103,Q01081 76 +RNA-binding domain superfamily [IPR035979] 0.5834306336191921 5.045648427399872 4.51985852522157e-07 0.0004609194177557 0.0002305127847868 135 Q8IXT5,Q9NWH9,Q14151,O95319,P38159,Q9NZI8,Q15233,P52272,Q14966,P98175,Q86V81,P08579,O95104,P23246,Q96T37,Q08170,Q9BY77,Q01130,O75494,P42696,P98179,Q96E39,Q9NR30,P26599,Q9NTZ6,Q01085,Q8WUA2,P08621,P19338,Q9BTD8,Q76FK4,Q13310,Q8NFH5,P05455,Q14498,P11940,Q02040,Q15287,P18615,Q05519,Q13283,Q9BQ39,P09012,P78332,Q13243,Q8IY67,Q9GZT3,Q9NW13,O95628,Q01844,Q8WXF1,Q15056,Q15424,Q96PK6,Q12849,P43243,Q9P2N5,P49756,Q9UN86,P84103,Q01081,Q9Y6M1,Q9BXP5,Q9UKM9,Q9Y3B4,Q5T8P6,Q9Y2U8,P23588,Q9UKV3,Q96I25,Q13151,Q9NW64,O75821,Q9Y4C8,Q9BZI7,P51991,P33240 77 +Zinc finger C2H2 superfamily [IPR036236] 0.6257765335762201 3.514932827342743 0.0004398652333572 0.3615814922918854 0.0406935462509485 26 Q5F1R6,Q7Z3K3,Q8N1G0,P17544,Q9Y467,Q96NC0,Q14966,Q9NX58,Q96JM3,Q9ULV3,O95785,Q9H582,Q969S3,Q92785,Q96KM6,Q9H3H1,P25490 17 +K Homology domain, type 1 superfamily [IPR036612] 0.5850079172823985 3.3146974262269 0.000917423697742 0.607885615356607 0.0406935462509485 27 Q96AE4,Q9Y6M1,Q8IWZ3,Q15637,O75179,Q96PU8,Q00341,Q92945,Q9NZI8 9 +Zinc finger, FYVE/PHD-type [IPR011011] 0.5547019472025175 3.081976141933348 0.0020563131791877 0.8774944445986268 0.0406935462509485 28 Q96T23,Q9BTC0,Q8WUB8,Q12830,Q15075,O14964,Q92576,Q92785,O94880,Q9UIG0,Q96L73,Q9Y2K7 12 +Kinesin motor domain superfamily [IPR036961] 0.6349820046337064 3.049409176929999 0.002292919511035 0.9038132170143132 0.0406935462509485 21 Q92614,Q99661,O94832,Q9UM54,Q02241,Q9Y496,Q7Z406,Q14807,Q86Y91,Q96Q89,P35580,O00159,P35579,P33176,O43795 15 +Zinc finger, RING/FYVE/PHD-type [IPR013083] 0.4384102219717689 3.03147339658833 0.002433633648341 0.91670208356531 0.0406935462509485 65 O60858,O75150,Q92785,Q13049,Q9UIG0,Q7Z6E9,Q96T23,Q8WUB8,P29083,Q12830,O75592,Q99590,Q9Y2K7,Q9UPT9,Q99496,Q15075,O14964,Q96L73,P14373,Q92576,Q13356,O94880,Q9BTC0 23 +SAP domain superfamily [IPR036361] 0.723550852372731 2.7415569957005355 0.0061148750934871 0.9980817087416388 0.0640688284022197 12 Q15424,Q8IX12,Q9NWH9,P82979,Q14151 5 +ENTH/VHS [IPR008942] 0.6367484712201943 2.703352897799188 0.0068643824336334 0.9991113540821902 0.0662581776835829 16 O95104,Q9NQG5,Q14677,O75146,O00291 5 +SH3-like domain superfamily [IPR036028] 0.4744408078024135 2.6255716594075436 0.0086503598403873 0.999858293310764 0.0787800628320987 37 Q07157,Q8IZP0,A1A4S6,P46108,Q9UDY2,Q9Y5K6,Q99961,Q9UJU6,Q9NZM3,Q9UKS6,Q5JRA6,Q13813,Q14168,O60504,Q9UQB8,Q8N3R9,Q14247,Q9UNF0 18 +PH-like domain superfamily [IPR011993] 0.4095366192368661 2.6217190385790587 0.008748752259317 0.9998719375118716 0.0789710380929502 64 Q13464,Q9UKX7,A1A4S6,Q9Y2J2,Q9Y5B9,Q9NZM3,Q92974,P26038,Q12802,P35241,Q92888,Q6WCQ1,P15311,Q9NQW6,Q8IZD4,P50570,P43487,Q9Y5S2,Q9Y490,P11274,O43491,Q8N8S7,O60343,Q01082,Q12979,P32780,P49792,Q96JJ3,Q9UQ16,Q9H4L5,P22059,O75116,Q9NVZ3 33 +Cyclophilin-like domain superfamily [IPR029000] 0.6121629466789733 2.489095210451932 0.0128068663722815 0.9999980493987152 0.0946594470994724 15 Q8WUA2,Q9Y3C6,Q13356,P30414,Q13427,Q6UX04 6 +Ribosomal protein L2, domain 2 [IPR014722] 0.6526569400730426 2.45638991272049 0.0140340793818416 0.9999994515435776 0.0985936366457161 13 P50914,P62917,P61254,Q5T653,Q92917 5 +PDZ superfamily [IPR036034] 0.4771409833431908 2.4295727780381853 0.0151166296508662 0.9999998211452062 0.1036681066859508 30 Q07157,Q9NR12,Q92614,Q9UDY2,Q09666,O00233,Q9H8Y8,Q14168,Q8N3R9,Q5EBL8,Q96HC4,O14745 12 +Bromodomain-like superfamily [IPR036427] 0.603106842634173 2.428924766026977 0.0151436744080457 0.9999998260853208 0.1036681066859508 15 Q9UIF9,Q86U86,O60885,Q15059,Q12830,Q9NRL2,P25440,Q9UIG0 8 +BRCT domain superfamily [IPR036420] 0.666673736634886 2.4122848103739822 0.0158528924309724 0.9999999165894814 0.1070857634410058 12 P09874,O60934,P49916,Q92922,P18887,Q14676,Q9NYB0 7 +WW domain superfamily [IPR036020] 0.6739074427175316 2.365910499291356 0.0179857918364692 0.9999999908772284 0.1153702107678653 11 Q8N3X1,O14776,Q13526,O60828,P46939 5 +SMAD/FHA domain superfamily [IPR008984] 0.7023828514274487 2.317386368270568 0.0204826942464164 0.99999999932024 0.1228961654784988 9 P46013,O60934,Q12972,P55196,Q14676,Q96T60 6 +Translation protein SH3-like domain superfamily [IPR008991] 0.6491072000073183 2.222495383286142 0.0262498456884343 0.9999999999983538 0.1387446201327122 11 P50914,P62917,P61254,Q02878,Q5T653,P61353,P46778 7 +Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047] 0.6722269796467444 2.1536067223765487 0.0312710266453728 0.9999999999999916 0.157125355558031 9 P34932,P0DMV9,O95757,P54652,P11142,Q9Y4L1 6 +Myosin S1 fragment, N-terminal [IPR008989] 0.9062327633756156 2.0972018876431275 0.0359757074782636 1.0 0.1767700362685898 4 Q9UM54,P35579,Q7Z406 3 +Heat shock protein 70kD, C-terminal domain superfamily [IPR029048] 0.6801267018806351 2.0848045359157004 0.0370870468249786 1.0 0.1767700362685898 8 P34932,P0DMV9,O95757,P54652,P11142,Q9Y4L1 6 +High mobility group box domain superfamily [IPR036910] 0.5902386309491973 2.068273871834669 0.0386142772412956 1.0 0.1831933152842862 13 P26583,Q86U86,Q00059,P17480,Q969G3,O94842,O15347,O75717,Q9NP66 9 +Dbl homology (DH) domain superfamily [IPR035899] 0.7234162853913606 2.064065118938314 0.0390115426237225 1.0 0.1842211735009119 7 Q12802,Q92888,P11274,Q9NZM3,Q92974 5 +CH domain superfamily [IPR036872] 0.4371194471037967 2.04588991540938 0.0407672027568648 1.0 0.1868578491087535 30 Q86VI3,Q14315,O75369,P46940,Q5M775,Q01082,Q86VS8,P21333,Q15149,P46939,Q96ED9 11 +TFIIS/LEDGF domain superfamily [IPR035441] 0.765014093582908 2.040346426419786 0.0413158337899659 1.0 0.1881346002935949 6 Q7Z4V5,Q14241,Q96QC0 3 +UBA-like superfamily [IPR009060] 0.4730894119292831 2.031403935890539 0.042214035497015 1.0 0.1892984686837011 24 Q04323,Q8NBM4,Q9UNZ2,Q7Z6Z7,Q14157 5 +Chromo-like domain superfamily [IPR016197] 0.6475438787741331 2.017578788341435 0.0436351478414402 1.0 0.1920497206559843 9 P45973,Q9P2D1,O14646,Q13185,Q14839,Q9UBU8,Q9HCK8 7 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.6610904346585036 1.9832608554247275 0.0473382994441096 1.0 0.1995250637726934 8 P98175,P49790 2 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.4881534364489898 1.930321223761196 0.0535670489081436 1.0 0.2170301422489303 21 Q8IWZ3,Q8IUH4,Q04721,Q9P0K7,O14974,O75179,Q9UBC1 7 +Immunoglobulin-like fold [IPR013783] 0.4030429274746166 1.8825779416608688 0.0597575880510836 1.0 0.2291456383913734 37 Q9BY67,O75147,Q7Z4H8,Q13308,P51610,P10586,O75592,Q14315,P30511,O75369,Q96KP1,O15344,P21333 13 +FERM superfamily, second domain [IPR035963] 0.6081568585440875 1.7970859104337364 0.0723219821388361 1.0 0.2552540546076569 9 Q9Y2J2,O43491,Q9Y490 3 +BRK domain superfamily [IPR037259] 0.9610923503440888 1.7635389209698795 0.0778096389175979 1.0 0.268394356488556 3 Q9P2D1 1 +FERM/acyl-CoA-binding protein superfamily [IPR014352] 0.5832056106406656 1.763080048406005 0.0778869897260907 1.0 0.268394356488556 10 O43491,Q9Y2J2,Q9H3P7,P15311,P26038,Q9Y490 6 +B30.2/SPRY domain superfamily [IPR043136] 0.5766617101353559 1.7245011809751971 0.0846174059452198 1.0 0.2857938876295504 10 P14373,O15344,Q92499,P19474 4 +Zinc finger, CCCH-type superfamily [IPR036855] 0.6927619512164274 1.6999017900594773 0.0891494001678394 1.0 0.293668717332567 6 Q9NW64,Q96QC0,Q8WU90,Q9UPT8 4 +Fibronectin type III superfamily [IPR036116] 0.6475332860588036 1.6821846689254252 0.0925330360448561 1.0 0.299211487634764 7 P51610,O75147,P10586 3 +SNF2-like, N-terminal domain superfamily [IPR038718] 0.4860580184909478 1.6206247368286577 0.1050981437435127 1.0 0.326153455581413 15 Q14527,Q9P2D1,Q9NRZ9,O60264,Q14839,Q9HCK8,Q6ZRS2 7 +RGS domain superfamily [IPR036305] 0.8845093715545762 1.6171773968732448 0.1058399939190664 1.0 0.326153455581413 2 P35579 1 +Chaperone J-domain superfamily [IPR036869] 0.4553425397702103 1.6083355485506583 0.1077617090474749 1.0 0.3300809105958692 20 Q5F1R6,Q8WXX5,O75190,Q99543,P25685,Q96EY1,O75937,Q9NXW2 8 +Histone-fold [IPR009072] 0.627325851591017 1.5786619885713622 0.1144136079672124 1.0 0.3408570256452924 7 P16104,Q9P0M6,O75367,Q9NRF9,P62805 5 +HIV integrase-binding domain superfamily [IPR036218] 0.8676957001102725 1.5457855950996813 0.1221563570745842 1.0 0.3500830838797967 2 Q7Z4V5 1 +Zinc finger, PARP-type superfamily [IPR036957] 0.8654906284454251 1.5364146688775366 0.1244367113412514 1.0 0.3515940320445331 2 P09874 1 +L27 domain superfamily [IPR036892] 0.7076788431608398 1.4995940413375155 0.1337195921383585 1.0 0.3556604085345555 5 Q8N3R9 1 +SMCs flexible hinge superfamily [IPR036277] 0.7064686512305172 1.494149156090678 0.1351366383458496 1.0 0.3580243405526406 5 O95347,Q9UQE7,Q14683 3 +Ribosomal protein L24e/L24 superfamily [IPR038630] 0.8539140022050822 1.487196419244592 0.1369629415228848 1.0 0.3612586959765598 2 Q9UHA3 1 +Immunoglobulin-like domain superfamily [IPR036179] 0.4550815628311802 1.4656191076560103 0.1427520827727288 1.0 0.3653191875651625 17 Q9BY67,Q13740,O75147,Q13308,P10586,P30511,Q9Y639,O15533,Q8WX93 9 +Adenylate kinase, active site lid domain superfamily [IPR036193] 0.8442668136714431 1.446164918604799 0.1481309507983363 1.0 0.3728883825777427 2 P27144 1 +I/LWEQ domain superfamily [IPR035964] 0.872622001654259 1.4206927723975655 0.1554060946167457 1.0 0.3810604731921407 3 O75146,Q9Y490 2 +Sec23/Sec24 helical domain superfamily [IPR036175] 0.6868517631593752 1.4057498388070564 0.1597984218765664 1.0 0.3835162125037594 5 O95486,O95487,Q15437 3 +Gelsolin-like domain superfamily [IPR036180] 0.6868517631593752 1.4057498388070564 0.1597984218765664 1.0 0.3835162125037594 5 O95486,O95487,Q15437 3 +HSP40/DnaJ peptide-binding [IPR008971] 0.670295242756981 1.3309986387371162 0.1831894588435743 1.0 0.4161542272170285 5 Q96EY1,P25685 2 +Zinc finger, Sec23/Sec24-type superfamily [IPR036174] 0.7140382811305823 1.295876026202128 0.1950181999363334 1.0 0.4333737776362964 4 Q15437 1 +Macro domain-like [IPR043472] 0.6593292100330712 1.2814600525230246 0.2000321226488421 1.0 0.4350378786819169 5 P28838,Q9P0M6 2 +Ribosomal protein S11 superfamily [IPR036967] 0.7965821389195332 1.243616951273579 0.2136405743789753 1.0 0.4527100711185673 2 P82912 1 +50S ribosomal protein L30e-like [IPR029064] 0.5263367274132689 1.2432395963234015 0.2137795554815884 1.0 0.4527100711185673 8 P62424,Q9HC36,P55769 3 +NET domain superfamily [IPR038336] 0.8218913702784655 1.2234068376545766 0.2211760720630313 1.0 0.4622942489842048 3 Q15059,P25440 2 +CRIB domain superfamily [IPR036936] 0.77976846747519 1.1725499431349915 0.240976332995785 1.0 0.4919814595250533 2 O96013 1 +Bromo adjacent homology (BAH) domain superfamily [IPR043151] 0.6839492553778233 1.1684770620888176 0.2426143864128449 1.0 0.4919814595250533 4 P26358,Q86U86,O94776 3 +PWI domain superfamily [IPR036483] 0.8030430512337214 1.1504131632517371 0.2499737411031046 1.0 0.500197060647804 3 O43395 1 +Rho GTPase activation protein [IPR008936] 0.4491870549051429 1.1498543924858855 0.2502038480317703 1.0 0.500197060647804 13 P11274,A1A4S6,Q9H0H5,Q86VI3,P46940,Q07960 6 +HSP90, C-terminal domain [IPR037196] 0.6781577495863237 1.1440112456492362 0.2526189732694219 1.0 0.500197060647804 4 P08238,Q12931,P07900 3 +Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039] 0.7723263506063915 1.1411995093069165 0.2537869085023585 1.0 0.500197060647804 2 P13984 1 +Ribosomal protein S7 domain superfamily [IPR036823] 0.766538037486215 1.1168702316530577 0.2640498143397645 1.0 0.5110641567866409 2 P46782 1 +Ribosomal protein L4 domain superfamily [IPR023574] 0.7607497243660755 1.092594274226516 0.2745719778022293 1.0 0.5212007683310689 2 Q9BYD3 1 +DNA-binding domain superfamily [IPR016177] 0.6639602724577622 1.0841681351732035 0.2782902572093175 1.0 0.522216926323977 4 P51608,O95983 2 +Ubiquitin activating enzyme, alpha domain superfamily [IPR023318] 0.7486218302094779 1.041927807798956 0.2974451505126221 1.0 0.545121451797653 2 Q9UBT2 1 +PPM-type phosphatase domain superfamily [IPR036457] 0.6038021857798223 1.0315047275775275 0.3023041923968317 1.0 0.5486659719657799 5 Q9P0J1 1 +Ubiquitin-like domain superfamily [IPR029071] 0.3068670276521164 1.0169752881844198 0.3091651853467678 1.0 0.5518703440281908 47 Q9Y5A7,Q9Y2J2,Q04323,Q9Y4E8,P26038,P35241,P15311,P61956,Q9UMX0,Q9BZE9,Q9Y490,Q5TDH0,O43491,Q9UNZ2,Q92575,P54727,Q8NCF5,P55196,Q15459 19 +Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091] 0.5511550411741166 1.015928444389952 0.3096634625010552 1.0 0.5518703440281908 6 P18754,O95071,Q8TD19,O75592 4 +MAN1, winged-helix domain [IPR041885] 0.7400771775082646 1.0064151395094756 0.3142159139515097 1.0 0.5544986716791348 2 Q8NC56 1 +Enolase-like, C-terminal domain superfamily [IPR036849] 0.7392502756339656 1.0029873948620576 0.3158669431358314 1.0 0.555490141376807 2 P09104 1 +Enolase-like, N-terminal [IPR029017] 0.7392502756339656 1.0029873948620576 0.3158669431358314 1.0 0.555490141376807 2 P09104 1 +Plakin repeat superfamily [IPR035915] 0.5955214963819041 0.9945521681622184 0.3199541208791419 1.0 0.5597825099429241 5 Q03001,Q15149,P58107 3 +ADF-H/Gelsolin-like domain superfamily [IPR029006] 0.3976324179028322 0.9902764834126312 0.322038997760361 1.0 0.5609266377263269 15 Q9Y281,O95486,Q13045,P60983,Q9UJU6,Q15437,O95487 7 +Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241] 0.7351157662623989 0.985873945119074 0.32419497387229 1.0 0.5633370925889878 2 Q9BSJ2 1 +Ribosomal protein L23/L15e core domain superfamily [IPR012678] 0.7524599267008957 0.9566449705303528 0.3387464823026906 1.0 0.5814444254252201 3 P62750 1 +Alpha-catenin/vinculin-like superfamily [IPR036723] 0.6286052211846569 0.93643251236246 0.349050544818891 1.0 0.5914145443775229 4 Q9Y490 1 +Nucleic acid-binding, OB-fold [IPR012340] 0.3064377610823313 0.902925729430325 0.3665653141142206 1.0 0.6089521504829073 41 Q8IX12,Q14690,P62917,Q04837,P25205,P49916,P33991,P62857,Q5T653,Q12904 10 +Immunoglobulin E-set [IPR014756] 0.37559080030199 0.8780701595424778 0.3799056456304159 1.0 0.6193719071365672 17 Q14315,O75369,O75592,Q96KP1 4 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.4322865016082035 0.8654356520708032 0.3867997199277826 1.0 0.6225159597584612 10 Q9Y6Y8,Q13136,Q9ULH0,Q6SZW1 4 +Lamin tail domain superfamily [IPR036415] 0.7281499862145002 0.8653063126351813 0.3868706869583591 1.0 0.6225159597584612 3 P02545,Q03252 2 +PABC (PABP) domain [IPR036053] 0.7198786876206208 0.8345996629290983 0.4039431520090564 1.0 0.6345372627864712 3 Q13310,P11940 2 +Peptidase M41-like [IPR037219] 0.695700110253577 0.8253059210997422 0.4091979310762006 1.0 0.6345372627864712 2 Q9Y4W6 1 +Ribosomal protein L13 superfamily [IPR036899] 0.6948732083792666 0.8219971075503235 0.4110785431085282 1.0 0.6345372627864712 2 P40429 1 +C2 domain superfamily [IPR035892] 0.314234148660106 0.8210953140754288 0.4115919789502169 1.0 0.6345372627864712 28 P11274,Q16513,Q9NZM3,Q6WKZ4,Q96N67,A0FGR8,Q6P1N0,Q96PE3 8 +Transcription elongation factor S-II, central domain superfamily [IPR036575] 0.7085745795423193 0.7929917631236906 0.4277826217861118 1.0 0.6406720157951307 3 Q92576,Q9BTC0 2 +Moesin tail domain superfamily [IPR008954] 0.7082988695891899 0.7919824716083408 0.4283708968355677 1.0 0.6406720157951307 3 P26038,P15311 2 +Ubiquitin-activating enzyme [IPR035985] 0.4417796723738137 0.7806005862246548 0.4350374468887259 1.0 0.6480771569730588 8 Q9UBT2,Q13564,Q9GZZ9,P22314 4 +Dimeric alpha-beta barrel [IPR011008] 0.7043729585175446 0.7776410397910758 0.4367806597943025 1.0 0.648495302751366 3 O75323 1 +Ribosomal protein L11, C-terminal domain superfamily [IPR036769] 0.6788864388092775 0.7586188397498157 0.4480805994364967 1.0 0.6604656234468592 2 Q9Y3B7 1 +Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796] 0.6788864388092775 0.7586188397498157 0.4480805994364967 1.0 0.6604656234468592 2 Q9Y3B7 1 +SWIB/MDM2 domain superfamily [IPR036885] 0.6983733112765345 0.7558368623550471 0.4497470125303726 1.0 0.661965299828254 3 P41214,Q96GM5 2 +ARFGAP/RecO-like zinc finger [IPR037278] 0.5817242857417423 0.7455711018802464 0.4559265450744187 1.0 0.6653005378768343 4 Q8N6T3 1 +ArfGAP domain superfamily [IPR038508] 0.5817242857417423 0.7455711018802464 0.4559265450744187 1.0 0.6653005378768343 4 Q8N6T3 1 +Ribosomal protein L37ae/L37e [IPR011331] 0.6725468577728706 0.7338238952612599 0.4630560751672035 1.0 0.6709051089070278 2 P61513 1 +AH/BAR domain superfamily [IPR027267] 0.3498902712597659 0.7195857920251345 0.4717800624779076 1.0 0.6806445031505881 18 A1A4S6,Q99961,Q9UKS6,Q9UQB8,O95219,Q9Y5X2,Q9UNF0 7 +ARID DNA-binding domain superfamily [IPR036431] 0.6876206231044915 0.7171237157444578 0.4732977635834259 1.0 0.6808844899704759 3 Q8IVW6,O14497 2 +LEM/LEM-like domain superfamily [IPR011015] 0.4873302728402284 0.7160685733698104 0.4739490077245469 1.0 0.6808844899704759 6 Q9Y2U8,P50402,Q8NC56 3 +Glutamine synthetase/guanido kinase, catalytic domain [IPR014746] 0.5725317153888585 0.7091597792133022 0.4782253297568695 1.0 0.6830134176865182 4 P12532,P48506,O75879 3 +RNA polymerase Rpb1, domain 3 superfamily [IPR042102] 0.6795545345457084 0.6884157094947749 0.4911910338665888 1.0 0.6912886045834191 3 O14802 1 +RNA polymerase Rpb1, clamp domain superfamily [IPR044893] 0.6795545345457084 0.6884157094947749 0.4911910338665888 1.0 0.6912886045834191 3 O14802 1 +RNA polymerase Rpb1, funnel domain superfamily [IPR038120] 0.6795545345457084 0.6884157094947749 0.4911910338665888 1.0 0.6912886045834191 3 O14802 1 +Integrin alpha, N-terminal [IPR028994] 0.6579382579933771 0.6775125669110134 0.4980807994076306 1.0 0.6913796684510752 2 P17301 1 +Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014] 0.6573869900771937 0.6754117110458072 0.4994142271162802 1.0 0.6921069709518946 2 P29401 1 +SUI1 domain superfamily [IPR036877] 0.6571113561190957 0.6743619720138474 0.5000812133250454 1.0 0.6921069709518946 2 P41214 1 +Formin, FH2 domain superfamily [IPR042201] 0.5631549917264114 0.6724587519890963 0.5012916909445875 1.0 0.6928421744762592 4 Q27J81,O60610,Q9NSV4 3 +Ribosomal protein S10 domain superfamily [IPR036838] 0.6560088202866516 0.6701676354125573 0.5027509329286972 1.0 0.6930780440086534 2 Q96GC5 1 +ATPase, nucleotide binding domain [IPR043129] 0.3265277649272822 0.6696406240086811 0.5030869107188409 1.0 0.6930780440086534 22 P0DMV9,O95757,P54652,Q9H981,Q9Y4L1 5 +Zinc-binding ribosomal protein [IPR011332] 0.6727322856355087 0.664375231653175 0.5064501812821787 1.0 0.6930780440086534 3 P61513,P83881 2 +Diaphanous, GTPase-binding domain superfamily [IPR044933] 0.6433296582138877 0.6224868644388207 0.5336217784220321 1.0 0.711780811399711 2 O60610 1 +Kelch-type beta propeller [IPR015915] 0.5495132931606065 0.6199546966141729 0.5352876136528075 1.0 0.711855757400083 4 P51610 1 +WD40-repeat-containing domain superfamily [IPR036322] 0.2579034425192182 0.6150941604260904 0.5384925383255323 1.0 0.7142553824343862 96 Q05048,Q13409,Q5TAQ9,Q16576,O43815,Q12834,Q9BSC4,O60271,Q6P2E9,P18583,Q9HC35,O43818,Q9NV06,Q13112,Q9C0J8,O15213 16 +Mib/herc2 domain superfamily [IPR037252] 0.6394707828004326 0.6081883589124496 0.5430625545074039 1.0 0.7175178828983835 2 Q9ULT8 1 +Concanavalin A-like lectin/glucanase domain superfamily [IPR013320] 0.322570193998478 0.6069714988436875 0.5438698268037221 1.0 0.717654881422764 21 P49257,P14373,Q92499,O15344,P19474 5 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.654382287096664 0.6009189602409283 0.5478939640750622 1.0 0.7202912674826206 3 Q96EY1 1 +Thiamin diphosphate-binding fold [IPR029061] 0.4305823902843184 0.5839196980340309 0.5592743398100148 1.0 0.7295488535537239 7 P08559,P29401,A1L0T0,Q02218,Q9UJ83,P11177 6 +GAR domain superfamily [IPR036534] 0.6325799338478415 0.5829194121597407 0.5599475519824708 1.0 0.7295488535537239 2 Q03001 1 +FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156] 0.5376079098031996 0.5751041143252509 0.5652208855516201 1.0 0.734427137914207 4 Q16881 1 +Translation elongation factor eEF-1beta-like superfamily [IPR036219] 0.6287210584343903 0.5689227118842016 0.5694085915172153 1.0 0.7370517301364969 2 P29692 1 +Translation elongation factor EF1B/ribosomal protein S6 [IPR014717] 0.6287210584343903 0.5689227118842016 0.5694085915172153 1.0 0.7370517301364969 2 P29692 1 +Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162] 0.6276185226019757 0.5649446017440471 0.5721114453276868 1.0 0.7385194207433168 2 Q5JTZ9 1 +Winged helix-like DNA-binding domain superfamily [IPR036388] 0.2597249465965586 0.5429803485458491 0.5871433328578226 1.0 0.753315974232678 53 P16403,P10412,P07305,P16402,Q6PKG0,P13984,Q5SSJ5,Q92922,P54132,P39019,Q15149,Q92522 12 +GYF-like domain superfamily [IPR035445] 0.6341506395301262 0.5332665834144789 0.5938490561685814 1.0 0.760007575021271 3 O95400 1 +DNA/RNA polymerase superfamily [IPR043502] 0.4855976447568381 0.5289778504620006 0.5968208151666459 1.0 0.7628536735212766 5 P54098 1 +PUA-like superfamily [IPR015947] 0.3596206168944288 0.469035782674717 0.6390440592724862 1.0 0.8067140352202178 10 P41214,O60832,Q9P016,Q15650 4 +MIT domain superfamily [IPR036181] 0.6116723108430069 0.4614197994934148 0.6444974490562125 1.0 0.8125925810103051 3 Q9UN37 1 +NTF2-like domain superfamily [IPR032710] 0.3948617683557102 0.426961737304143 0.669407197049803 1.0 0.8336939450437106 7 Q13283,Q9BRJ2 2 +PX domain superfamily [IPR036871] 0.314945652801163 0.3928886459828299 0.6944017278583021 1.0 0.8564567864757777 14 O60493,Q9Y5X2 2 +GroEL-like equatorial domain superfamily [IPR027413] 0.3523888428610937 0.3887484869385356 0.6974622106233865 1.0 0.8571222347419931 9 P50991,P10809,P40227,P78371,P48643,P49368,P17987,P50990 8 +TCP-1-like chaperonin intermediate domain superfamily [IPR027410] 0.3523888428610937 0.3887484869385356 0.6974622106233865 1.0 0.8571222347419931 9 P50991,P10809,P40227,P78371,P48643,P49368,P17987,P50990 8 +GroEL-like apical domain superfamily [IPR027409] 0.3523888428610937 0.3887484869385356 0.6974622106233865 1.0 0.8571222347419931 9 P50991,P10809,P40227,P78371,P48643,P49368,P17987,P50990 8 +DUSP-like superfamily [IPR035927] 0.5865364678176079 0.3859038939043557 0.6995678466738895 1.0 0.8577741657260717 3 P51784 1 +ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802] 0.5722160970231421 0.3789948062627716 0.7046917206616017 1.0 0.860821024041717 2 P12532 1 +Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055] 0.5828508409153534 0.3753060782797348 0.7074328461865371 1.0 0.8621045437398661 3 Q96G03,O95394 2 +Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900] 0.5828508409153534 0.3753060782797348 0.7074328461865371 1.0 0.8621045437398661 3 Q96G03,O95394 2 +Homeobox-like domain superfamily [IPR009057] 0.2895811110020741 0.3493825341672197 0.7268021438825016 1.0 0.8804491529217954 19 Q7Z3K3,Q8IXM2,Q8TAQ2,Q99459,Q99543,O94776,Q92922,Q9NYB0,Q9H2P0,Q13330,P26367 11 +FF domain superfamily [IPR036517] 0.5705292848608959 0.3408264519210511 0.7332342357114765 1.0 0.8861361616418318 3 O14776 1 +HRDC-like superfamily [IPR010997] 0.4515051076120618 0.2884216401870885 0.7730240047443344 1.0 0.9192443027166812 4 O15514,P54132 2 +Prefoldin [IPR009053] 0.3798142516262363 0.2829856055533071 0.7771878713037403 1.0 0.9207103701856156 6 O15212 1 +von Willebrand factor A-like domain superfamily [IPR036465] 0.2791801578075343 0.2814482234874712 0.7783666352377567 1.0 0.9209167968303574 18 O95486,Q71SY5,P17301,Q15436,A3KMH1,Q15437,P55036,O95487 8 +Six-hairpin glycosidase superfamily [IPR008928] 0.5457901591283688 0.2763149015983004 0.7823062114736936 1.0 0.9209167968303574 3 P35573 1 +Aconitase, iron-sulfur domain [IPR036008] 0.5361080485115709 0.2756989823638686 0.7827792773058038 1.0 0.9209167968303574 2 Q99798 1 +Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931] 0.5361080485115709 0.2756989823638686 0.7827792773058038 1.0 0.9209167968303574 2 Q99798 1 +Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928] 0.5361080485115709 0.2756989823638686 0.7827792773058038 1.0 0.9209167968303574 2 Q99798 1 +SWAP/Surp superfamily [IPR035967] 0.3748675741206547 0.2668787133629061 0.7895625466739777 1.0 0.9246312257261278 6 Q15459,Q8IX01 2 +GAT domain superfamily [IPR038425] 0.5311466372656983 0.2627996012637613 0.7927050428827227 1.0 0.9270958125996412 2 Q6ZVM7 1 +Histidine kinase/HSP90-like ATPase superfamily [IPR036890] 0.3076136423760355 0.2563770099045359 0.7976597381954105 1.0 0.9270958125996412 11 P08238,Q12931,P54277,P07900 4 +GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266] 0.5329867531236158 0.2455775889271889 0.8060092394831055 1.0 0.9289598014381556 3 Q8NCN5 1 +BAG domain superfamily [IPR036533] 0.5307416597739139 0.2403829013708272 0.810033432383825 1.0 0.9314927858303286 3 O95429,O95817 2 +Pseudouridine synthase, catalytic domain superfamily [IPR020103] 0.4209325740684083 0.207946860742171 0.8352704592501705 1.0 0.9445408740966452 4 O60832 1 +Metal-dependent hydrolase, composite domain superfamily [IPR011059] 0.509127770474956 0.1934534116357896 0.8466038889255065 1.0 0.9520550980319724 3 Q9BPU6 1 +Integrin domain superfamily [IPR032695] 0.5058533707393016 0.1868404782821559 0.8517857086426974 1.0 0.9557991450116076 3 P17301 1 +Winged helix DNA-binding domain superfamily [IPR036390] 0.2187968640503297 0.181798069692934 0.855741199440988 1.0 0.9582735806098578 50 P16403,P10412,P07305,P16402,Q5SSJ5,Q92522 6 +HotDog domain superfamily [IPR029069] 0.3446467991169951 0.1784187497831401 0.8583941253472083 1.0 0.9586076161714984 6 O14734,P51659,Q9Y305,Q9NPJ3,Q8WUY1 5 +HECT, E3 ligase catalytic domain [IPR035983] 0.3038090455488795 0.1780329959510222 0.8586970626418959 1.0 0.9586076161714984 8 O95071,Q7Z6Z7,Q9ULT8 3 +WD40/YVTN repeat-like-containing domain superfamily [IPR015943] 0.2286670817658356 0.1646620339583929 0.8692100015077402 1.0 0.9619804391180308 106 Q05048,Q13409,Q5TAQ9,Q16576,O43815,Q12834,Q9BSC4,O60271,Q6P2E9,Q9HC35,Q13112,O43818,Q9NV06,P35658,Q9C0J8,O15213 16 +Ribosomal L18e/L15P superfamily [IPR036227] 0.4937862137567328 0.1636211454440282 0.8700293973908471 1.0 0.9619804391180308 3 Q9P015 1 +Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095] 0.4929693961951982 0.1621152778610257 0.8712150753488062 1.0 0.9619804391180308 3 Q9BYD6,O76021 2 +Ribosomal protein L1-like [IPR023674] 0.4929693961951982 0.1621152778610257 0.8712150753488062 1.0 0.9619804391180308 3 Q9BYD6,O76021 2 +2Fe-2S ferredoxin-like superfamily [IPR036010] 0.4840132304299745 0.1573619433276642 0.8749596045566439 1.0 0.9637783981077503 2 P28331 1 +SNARE [IPR010989] 0.3125943917259631 0.1479788247949849 0.8823594796090695 1.0 0.9698347728461756 7 Q12846,O43752 2 +6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927] 0.2825186412593257 0.1366993545231143 0.8912684397588373 1.0 0.973577841725103 9 Q53H96,Q96C36,P32322,P31937,O60701,Q16836,Q49A26,P40939 8 +Creatinase/aminopeptidase-like [IPR036005] 0.3022357162572432 0.1233225402762839 0.9018516925100905 1.0 0.982787100812278 7 P12955,Q9NQH7,Q9Y5B9,P53582,Q9NQW7,Q9UQ80 6 +Translation protein, beta-barrel domain superfamily [IPR009000] 0.2355223053477513 0.119252321661331 0.905075455664056 1.0 0.9840433236097382 21 Q96RP9,P18077,Q05639,Q5JTZ9,P15170,P39023,P46199,O00178,P09001,Q15029,Q9NY12,Q9BTE6,Q96HR8,P41091,Q9Y450,P49588,Q7Z2Z2,O60841,P49411,Q8N442 20 +Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449] 0.4652399192809793 0.1159721963553712 0.907674577176812 1.0 0.9840433236097382 3 Q9UBT2 1 +Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149] 0.3717595146166692 0.1079700132604388 0.9140194790755248 1.0 0.9843980216176654 4 Q9NQW7,P12955,Q9Y5B9 3 +Protein kinase-like domain superfamily [IPR011009] 0.1997150748935856 0.100608372692896 0.9198613499868172 1.0 0.9845315603216724 83 Q13464,Q16513,P51956,O00311,Q13308,Q2M2I8,Q13523,P42345,O96013,Q99640,Q13043,Q9H2G2,O95747,O75116,P11802,Q9Y5S2 16 +E3-binding domain superfamily [IPR036625] 0.4483043837882506 0.0925080640481415 0.926294384512414 1.0 0.9893405991650912 3 P10515,P11182 2 +Succinyl-CoA synthetase-like [IPR016102] 0.3596249310535054 0.0891025094122599 0.9290004431068656 1.0 0.9911929413901706 4 P53396,Q96I99,P53597 3 +Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179] 0.4299889746416646 0.0757249217977878 0.9396379481892048 1.0 0.9973264382445254 2 Q02218 1 +Band 7/SPFH domain superfamily [IPR036013] 0.2586132478540875 0.0721546004419811 0.942478874549988 1.0 0.9982642284953146 8 O75955,Q9UJZ1 2 +EF-G domain III/V-like [IPR035647] 0.3160186613937541 0.0650207151543758 0.94815750684469 1.0 0.9989460744219828 5 Q96RP9 1 +PITH domain superfamily [IPR037047] 0.4178610804851015 0.0628648826063156 0.9498740991295946 1.0 0.9989460744219828 2 O43396 1 +Ferritin-like superfamily [IPR009078] 0.41179713340682 0.0571188673864634 0.9544505069578142 1.0 0.9989460744219828 2 Q7LG56 1 +Ribonucleotide reductase-like [IPR012348] 0.41179713340682 0.0571188673864634 0.9544505069578142 1.0 0.9989460744219828 2 Q7LG56 1 +Ribonuclease H-like superfamily [IPR012337] 0.2149155201686392 0.0539684761229723 0.9569602800338708 1.0 0.9989460744219828 17 Q9GZR2,Q5SVZ6 2 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.2631303336372774 0.0529738912432085 0.9577527102657168 1.0 0.9989460744219828 7 P33908,Q9NS86 2 +HRDC domain superfamily [IPR044876] 0.4059173152155868 0.0485277564422809 0.9612956440531256 1.0 0.9997711964774468 3 P54132 1 +Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047] 0.2335939897580628 0.0365167834389411 0.9708702963852676 1.0 1.0 8 Q9HC35 1 +SNase-like, OB-fold superfamily [IPR035437] 0.3848910945685093 0.0336947407261239 0.9731205728854566 1.0 1.0 3 Q9Y2W6,Q7KZF4 2 +Pyridoxal phosphate-dependent transferase, small domain [IPR015422] 0.2021097092754986 0.0321933480863131 0.9743178608893954 1.0 1.0 17 P23378,P80404,Q8TD30,Q96I15 4 +Oxysterol-binding protein superfamily [IPR037239] 0.2579062764312614 0.027251454495461 0.9782591761726058 1.0 1.0 6 P22059 1 +Peptidyl-tRNA hydrolase II domain superfamily [IPR023476] 0.3133958103638269 0.0116239691543292 0.9907256233307804 1.0 1.0 2 Q6GMV3 1 +SCP2 sterol-binding domain superfamily [IPR036527] 0.3245106148331909 0.0102366984152778 0.9918324390275486 1.0 1.0 3 P51659,Q6YN16 2 +NAP-like superfamily [IPR037231] 0.2651476671811309 0.0101405518444558 0.9919091489102958 1.0 1.0 4 Q9H0U9 1 +LSM domain superfamily [IPR010920] 0.1914893617021247 0.0064634469784524 0.9948429513532868 1.0 1.0 11 P62316,Q9Y333,Q9UK45,P62312,Q9BX40,P62314,P62318,O95777,Q9Y4Y9,P62304 10 +RuvA domain 2-like [IPR010994] 0.2832369477846274 0.0045560789807487 0.9963647875000026 1.0 1.0 3 Q14807 1 +Pyridoxal phosphate-dependent transferase [IPR015424] 0.17550024549501 0.0025728783776301 0.9979471423305504 1.0 1.0 19 P23378 1 +Pyridoxal phosphate-dependent transferase, major domain [IPR015421] 0.17550024549501 0.0025728783776301 0.9979471423305504 1.0 1.0 19 P23378 1 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8578e8678f281ead1017540331ae89529704e9a2 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "AN1-like Zinc finger [IPR035896]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP synthase-coupling factor 6 superfamily, mitochondrial [IPR036204]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP12 orthogonal Bundle domain superfamily [IPR023335]", "ATP12, ATP synthase F1-assembly protein, N-terminal [IPR042272]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioester hydrolase/BAAT, N-terminal [IPR042490]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha-macroglobulin, receptor-binding domain superfamily [IPR036595]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apolipoprotein C-I domain superfamily [IPR043081]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin, N-terminal [IPR014753]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "Atg6/Beclin C-terminal domain superfamily [IPR038274]", "Autophagy protein Atg5, UblA domain [IPR042527]", "Autophagy protein Atg5, helix rich domain [IPR042526]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Bcr-Abl oncoprotein oligomerisation domain superfamily [IPR036481]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CGI121/TPRKB superfamily [IPR036504]", "CH domain superfamily [IPR036872]", "CKK domain superfamily [IPR038209]", "CPI-17 superfamily [IPR036658]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chondroitin AC/alginate lyase [IPR008929]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c oxidase-like, subunit I superfamily [IPR036927]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DIX domain superfamily [IPR038207]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deoxyhypusine synthase superfamily [IPR036982]", "DhaL domain superfamily [IPR036117]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 2 [IPR042264]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Disintegrin domain superfamily [IPR036436]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP cyclohydrolase 1 type 2/Nif3 superfamily [IPR036069]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycolipid transfer protein superfamily [IPR036497]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "Hypoxia-inducible factor 1-alpha inhibitor, domain II [IPR027452]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Impact, N-terminal domain superfamily [IPR036956]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L1 transposable element, C-terminal domain [IPR042566]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTERF superfamily, mitochondrial/chloroplastic [IPR038538]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Notch-like domain superfamily [IPR035993]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRC-barrel-like superfamily [IPR011033]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PUB-like domain superfamily [IPR036339]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein translocase SecE domain superfamily [IPR023391]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Putative deacetylase LmbE-like domain superfamily [IPR024078]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RNase P subunit Pop5/Rpp14/Rnp2-like domain superfamily [IPR038085]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "RecQ mediated genome instability protein, N-terminal, subdomain 2 [IPR042470]", "RecQ-mediated genome instability protein 1, N-terminal, subdomain 1 superfamily [IPR044881]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin kinase domain superfamily [IPR023465]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease P/MRP subunit Rpp29 superfamily [IPR036980]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rof/RNase P-like [IPR023534]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAP30, C-terminal domain superfamily [IPR038291]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfatase-modifying factor enzyme superfamily [IPR042095]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription factor EnY2 superfamily [IPR038212]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "Tumor necrosis factor alpha-induced protein 8-like superfamily [IPR038355]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "UbiA prenyltransferase superfamily [IPR044878]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS28, C-terminal domain superfamily [IPR037206]", "VPS28, N-terminal domain superfamily [IPR038358]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALKBH5", "ALYREF", "AMFR", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOC1", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARVCF", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5J", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATPAF2", "ATRX", "ATXN10", "AURKA", "AURKB", "B3GAT3", "B4GALT1", "B4GALT3", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAS3", "BCAT2", "BCKDK", "BCL2L12", "BCL2L13", "BCR", "BCS1L", "BECN1", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C10orf76", "C1QBP", "C2CD2", "C2CD2L", "C2CD5", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC7", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPV", "CEP170", "CEPT1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNN3", "CNNM4", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COG8", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLST", "DMAC2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAM129B", "FAM173A", "FANCG", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEM1A", "FEN1", "FERMT2", "FH", "FHOD1", "FIGNL1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1", "FNBP4", "FNDC3A", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLPH3", "GOLPH3L", "GOPC", "GORASP2", "GOSR2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPRASP2", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HMBS", "HMCES", "HMG20A", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS4", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRS4", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAM3", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "LACTB", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC45", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1A", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED21", "MED25", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL4", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTERF3", "MTF2", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKIPSD", "NCL", "NCOA5", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK3", "NEK9", "NELFE", "NENF", "NFATC2IP", "NFKBIL1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PAX6", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD11", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PI4KB", "PIAS2", "PICALM", "PIGG", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "R3HCC1", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN2", "RMDN3", "RMI1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN4IP1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61G", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMS", "SMU1", "SMYD3", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPATS2L", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX4", "STX5", "STX6", "STX7", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TAF15", "TAGLN2", "TALDO1", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "THADA", "THEM6", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM115", "TMEM131", "TMEM14C", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNFAIP8", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPRKB", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPYL1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UCK2", "UFC1", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13D", "VPS16", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR89", "WDR91", "WFS1", "WIZ", "WNK1", "WRAP73", "WRN", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YKT6", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZDHHC13", "ZFPL1", "ZFR", "ZFYVE16", "ZMAT2", "ZMYM1", "ZMYND8", "ZNF281", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZNF687", "ZPR1"], "leading_proteins": ["AAK1", "AARS", "AARS2", "AARSD1", "ABAT", "ABI1", "ABR", "ACBD3", "ACIN1", "ACLY", "ACO2", "ACOT13", "ACOT8", "ACOT9", "ACTR8", "ADNP", "AFDN", "AFG3L2", "AGL", "AHNAK", "AIMP1", "AK4", "AKAP13", "AKAP17A", "ALCAM", "ALYREF", "ANKHD1", "ANKRD17", "ANLN", "ARFGAP1", "ARHGAP1", "ARHGAP10", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID3B", "ASPSCR1", "ATF7", "BAG3", "BAG4", "BAIAP2", "BAP18", "BAZ1A", "BAZ1B", "BAZ2A", "BCR", "BLM", "BPTF", "BRD2", "BRD3", "BRD4", "CADM1", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT8", "CD2AP", "CD2BP2", "CDC20", "CDC42BPB", "CDC5L", "CDC7", "CDK4", "CELF2", "CFL2", "CHAF1B", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHD8", "CIZ1", "CKMT1A*", "CLINT1", "CNOT4", "CRK", "CSTF1", "CSTF2", "CTTN", "CWC27", "DBNL", "DBT", "DCAF13", "DCAF8", "DCP1B", "DDI2", "DDX1", "DDX21", "DDX50", "DIAPH1", "DIAPH3", "DIDO1", "DKC1", "DLAT", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJB6", "DNAJC2", "DNAJC21", "DNAJC8", "DNAJC9", "DNM2", "DNM3", "DNMT1", "DOCK7", "DPF2", "DPYSL5", "DST", "DYNC1I2", "EDC4", "EEA1", "EEF1A2", "EEF1D", "EFL1", "EFTUD2", "EIF2D", "EIF2S3", "EIF3G", "EIF4B", "EIF4H", "EIF5B", "ELMO2", "ELOA", "EMD", "EML4", "ENAH", "ENO2", "EPB41L2", "EPB41L3", "EPPK1", "ESF1", "ESYT2", "EWSR1", "EXOC2", "EZR", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FNBP4", "FUBP1", "G3BP1", "G3BP2", "GAR1", "GATB", "GCLC", "GFM1", "GLDC", "GLYR1", "GMFB", "GORASP2", "GPKOW", "GPT2", "GRSF1", "GSPT1", "GTF2E1", "GTF2F2", "GTF2H1", "GTPBP1", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADH", "HADHA", "HBS1L", "HCFC1", "HDGFL2", "HDLBP", "HECTD1", "HELLS", "HGS", "HIBADH", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HLA-F", "HLTF", "HMG20A", "HMGB2", "HMGB3", "HNRNPA0", "HNRNPA3", "HNRNPM", "HOOK2", "HOOK3", "HP1BP3", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPD1", "HUWE1", "HYOU1", "IGF2BP1", "IGF2BP2", "ILVBL", "INF2", "INPP4A", "IQGAP1", "IQGAP3", "ITGA2", "ITSN2", "KDELC2", "KDM2A", "KHSRP", "KIDINS220", "KIF18B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF5B", "LANCL2", "LAP3", "LARP1", "LEMD2", "LEMD3", "LIG3", "LMAN1", "LMNA", "LMNB2", "LSM14B", "LSM2", "LSM5", "LSM6", "LSM7", "LSM8", "LYAR", "MAN1A1", "MATR3", "MBD3", "MCM3", "MCM4", "MDC1", "MECP2", "MED25", "METAP1", "MIA3", "MID1", "MKI67", "MORF4L1", "MPP2", "MPP5", "MPRIP", "MRM3", "MRPL1", "MRPL11", "MRPL15", "MRPL2", "MRPL3", "MRPL4", "MRPL45", "MRPL48", "MRPS11", "MSN", "MTA1", "MTA2", "MTIF2", "MTOR", "MYCBP2", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAE1", "NAF1", "NBN", "NCBP3", "NCL", "NDUFS1", "NECAP2", "NEK3", "NEK9", "NELFE", "NFATC2IP", "NFKBIL1", "NIPSNAP2", "NKTR", "NOL10", "NOL8", "NONO", "NOTCH2", "NPTN", "NSD1", "NSFL1C", "NUB1", "NUP153", "NUP214", "NUP35", "NUP50", "OBSL1", "OGDH", "OSBP", "OSBPL3", "OXSR1", "PA2G4", "PABPC1", "PABPC4", "PACSIN2", "PACSIN3", "PAK4", "PALLD", "PARP1", "PAX6", "PBRM1", "PDCD11", "PDHA1", "PDHB", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDZD11", "PEPD", "PFDN6", "PGM2", "PGM3", "PHF10", "PHF14", "PHF3", "PIN1", "PKMYT1", "PKN2", "PLEC", "PMS1", "PNKP", "POGZ", "POLDIP3", "POLE3", "POLG", "POLR2D", "POLR3A", "PPFIA1", "PPIG", "PPIL1", "PPIL2", "PPIL4", "PPP1R10", "PPP1R12A", "PPP1R8", "PQBP1", "PRPF3", "PRPF4B", "PSMD4", "PSMD9", "PSPC1", "PTBP1", "PTK7", "PTPRF", "PTRHD1", "PYCR1", "PYCR2", "PYCR3", "QKI", "RAB11FIP1", "RACGAP1", "RAD23B", "RAI14", "RALY", "RANBP1", "RANBP2", "RAVER1", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM42", "RBM6", "RBMX", "RBMXL1", "RCC1", "RDX", "REXO4", "RNF2", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RPL13A", "RPL14", "RPL21", "RPL23A", "RPL26", "RPL27", "RPL3", "RPL35A", "RPL36A", "RPL37A", "RPL6", "RPL7A", "RPL8", "RPRD1B", "RPS19", "RPS28", "RPS5", "RRM2B", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "SAFB", "SAFB2", "SALL2", "SARM1", "SARNP", "SCAF11", "SCAF4", "SCLY", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SF1", "SF3A1", "SF3B6", "SFPQ", "SH3GL1", "SLC9A3R1", "SLIRP", "SLK", "SLTM", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SND1", "SNRNP70", "SNRPA", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX3", "SNX4", "SNX8", "SON", "SORBS3", "SPAG9", "SPECC1", "SPTAN1", "SPTBN1", "SRCAP", "SRRT", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SSB", "SSBP1", "STK4", "STOML2", "STRN", "STX4", "STX6", "SUCLG1", "SUCLG2", "SUGP2", "SUMO2", "SUPT16H", "TAPBP", "TBC1D4", "TCERG1", "TCP1", "TDRKH", "TERF2IP", "TFAM", "THEM6", "THYN1", "TIAL1", "TJP1", "TJP2", "TKT", "TLN1", "TOM1L2", "TOX4", "TRAP1", "TRIM13", "TRIM21", "TRIM27", "TRIM32", "TRIP4", "TRIT1", "TSPYL1", "TUBGCP2", "TUFM", "TXNL1", "TXNRD1", "U2AF1", "UBA1", "UBA2", "UBA5", "UBAC2", "UBAP2L", "UBQLN1", "UBR5", "UBTF", "UBXN1", "UBXN4", "UGDH", "UPF3B", "USP11", "USP15", "USP22", "UTRN", "VPS4A", "VWA8", "WDHD1", "WDR33", "WDR46", "WIZ", "XPNPEP1", "XPNPEP3", "XRCC1", "YY1", "ZC3H15", "ZC3H4", "ZDHHC13", "ZMAT2", "ZMYM1", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZNF687"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8a1fdf51ddd3371c3a92a5238b5a6f2398d4746f --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d4de19a26608d02add937571b53f4465e0bc717aa382293eb4af92fff35876f0 +size 80314 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f97a4a1c92449fdbe81f37bdb9c377742b1edba1 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.75 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fc74ebc71d25642ecc37fad6414f6b86e56eed67 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..911c0f98110fcfc0055bf4e7c9370c039a6363c6 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bf8e168b4678848c95ea32eac1bfaf57f067398e --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "EIF5A", "FASN", "LDLR", "NOTCH2", "SLIT2"], "leading_proteins": []} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..10762463f590b74e51e7af84497d085620fdf8e7 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Ankyrin repeat [IPR002110]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2b5bdf508a2c0d2fb38abf54bb4893f673b5931d --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b685f3356e3f72693f7381a9817c878278f112a55c0e305ea30201a159f4c80f +size 194959 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..4d451286bb1a1bd82ad7f90c6b52b1d29d96f7c5 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Ankyrin repeat [IPR002110]", "1": "Spectrin/alpha-actinin [IPR018159]", "2": "Spectrin repeat [IPR002017]", "3": "WD40 repeat [IPR001680]", "4": "HEAT, type 2 [IPR021133]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a3fcb8ff4dae5e24498f5960e37acda492d0aebd --- /dev/null +++ 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a/interpro_repeat/basic/plot_3.png b/interpro_repeat/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..11449d97090b28a772db66d2fca97dab701e864d --- /dev/null +++ b/interpro_repeat/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fe97677c528b51b72d5e695f70d4cc6f21d5edef24356705b755a730346cd0fe +size 146245 diff --git a/interpro_repeat/basic/plot_4.png b/interpro_repeat/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..7532cc9e1a4d895460d1942df4bb5907bc816ce7 --- /dev/null +++ b/interpro_repeat/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cf7c5166549ee5b7510ba818617f17ef781cece74988d3691a9a46e70953be66 +size 138908 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3b5c33e31280db0f46618ac2fd787e6c596aa049 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:efd472516d10d27779bcc86493bc0545eacb3d396a808a2c562c1a01a5414ef7 +size 90238 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bc5636193032181cd254ab5c2fbc755b35b225b3 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Ankyrin repeat [IPR002110] 7 19 2.16412929691541 0.0304544276253513 5.674757281553398 17.478155339805824 -0.281648842867693 0.599481045282697 3.528117803071475 3.873235081335371 0.7759816171895568 0.2944480039093034 1.0 0.4872995681469994 0.738010173461058 0.8479123460010873 0.6496923711790646 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..064f4aa73476754511e73f9690a18c184815d57c --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 80, + "title": "Average number of proteins per term", + "value": 5.7125 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8df8d658b14bef767792506e8a2ee908ef407da3 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7397602222ac48728bdf057f380dc12c5a723b6e --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,15 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ankyrin repeat [IPR002110] 0.534628696195053 2.16412929691541 0.0304544276253513 0.9157716694997662 0.1015147587511711 19 Q8IWZ3,Q8IUH4,Q04721,Q9P0K7,O14974,O75179,Q9UBC1 7 +Filamin/ABP280 repeat-like [IPR017868] 0.7864827586206665 1.8507174088753728 0.0642102182253852 0.9950538886056196 0.1902524984455857 5 P21333,Q14315,O75369,O75592 4 +Spectrin/alpha-actinin [IPR018159] 0.5808350940099252 1.8174691235313745 0.0691453119389384 0.9967599536260426 0.1975580341112527 11 Q03001,Q8WXH0,Q13813,Q9UPN3,Q01082,Q15149,P46939,P12814,O43707 9 +Spectrin repeat [IPR002017] 0.5962441314554026 1.7296422199116952 0.0836942178805824 0.9990811721158904 0.2159850784015029 9 Q03001,Q8WXH0,Q13813,Q9UPN3,Q01082,P46939,P12814,O43707 8 +Filamin/ABP280 repeat [IPR001298] 0.7862658576944189 1.6012105302103337 0.1093302973205943 0.999905085108249 0.2363898320445281 4 P21333,Q14315,O75369 3 +WD40 repeat [IPR001680] 0.2808182271707354 1.0363108715245626 0.300057135906691 0.9999999999995972 0.4616263629333708 91 Q12834,Q9BSC4,Q9NV06,Q05048,Q16576,Q8WUA4,Q9ULV4,P55735,P35658,O15213,Q13409,Q14137,O43815,Q6P2E9,Q969X6,O43818,O94979,Q9C0J8,Q5TAQ9,Q15291,Q9HC35,Q13112,Q96EE3 23 +Plectin repeat [IPR001101] 0.5955214963819041 0.9945521681622184 0.3199541208791419 0.99999999999996 0.4829496164213462 5 Q03001,Q15149,P58107 3 +Regulator of chromosome condensation, RCC1 [IPR000408] 0.5338260756610067 0.7255416966809608 0.4681197743591785 1.0 0.6040255153021657 5 P18754,Q8TD19,O75592 3 +Integrin alpha beta-propellor [IPR013519] 0.6579382579933771 0.6775125669110134 0.4980807994076306 1.0 0.6226009992595383 2 P17301 1 +FG-GAP repeat [IPR013517] 0.6579382579933771 0.6775125669110134 0.4980807994076306 1.0 0.6226009992595383 2 P17301 1 +Kinesin light chain repeat [IPR015792] 0.6240352811466282 0.5520814965128461 0.5808925186347513 1.0 0.7041121437996987 2 Q07866 1 +Leucine rich repeat 4 [IPR025875] 0.6142817755720946 0.4695636658601417 0.6386667887327175 1.0 0.7404832333132957 3 Q8N1G4,Q13045 2 +Tetratricopeptide repeat 1 [IPR001440] 0.3549162738029306 0.4459135573960826 0.6556596887037691 1.0 0.7493253585185933 10 Q9H6T3 1 +HEAT, type 2 [IPR021133] 0.2449543820845986 0.0908156069150355 0.9276391087724224 1.0 0.9408952208048116 13 Q9P260,Q7Z460,Q92616,Q86Y56,P30154,Q8TF05,Q99570,Q9BU89,Q14008,P30153,Q8TEX9,Q14974 12 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..deca7ea918c14c96fdcf78dd702b2ee7c12d9bfa --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "AGAP3", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC6", "ARMCX3", "ARVCF", "ASPH", "BBS4", "BIRC6", "BOP1", "BRAT1", "BUB3", "CABIN1", "CAST", "CD320", "CDC20", "CDC23", "CDC27", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DCAF8", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EED", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FANCG", "FEM1A", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HUWE1", "IFIT5", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "ITGA2", "ITGAV", "JUP", "KAT7", "KDELC2", "KDM2A", "KEAP1", "KIAA1468", "KIDINS220", "KLC1", "KLC2", "KLHDC4", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LARP1", "LDLR", "LLGL1", "LRBA", "LRCH2", "LRPPRC", "LRRC1", "LRRC40", "LRRC45", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MKI67", "MPDU1", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NAA16", "NASP", "NEK9", "NFKBIL1", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NOL10", "NOP2", "NOP9", "NOTCH2", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM3", "PWP1", "PWP2", "RABGGTA", "RABGGTB", "RACK1", "RAE1", "RAI14", "RANBP2", "RANBP6", "RANGAP1", "RAP1GDS1", "RBBP4", "RBBP5", "RBBP7", "RCC1", "RCC2", "RNH1", "RPAP3", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC13", "SEC31A", "SEH1L", "SEL1L", "SGTA", "SHCBP1", "SHOC2", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL1XR1", "TBL2", "TBL3", "TEX10", "TGFBRAP1", "THOC3", "THOC6", "TLE3", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TRIM32", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC4", "TTC7B", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR89", "WDR91", "WFS1", "WRAP73", "XAB2", "XPO1", "ZDHHC13"], "leading_proteins": ["ACTN1", "ACTN4", "ANKHD1", "ANKRD17", "BOP1", "CDC20", "CHAF1B", "CKAP5", "CLASP1", "CORO1C", "CSTF1", "DCAF13", "DCAF8", "DNAAF5", "DOHH", "DST", "DYNC1I2", "EDC4", "EML4", "EPPK1", "FLII", "FLNA", "FLNB", "FLNC", "GCN1", "GTF3C2", "IPO4", "ITGA2", "KIAA1468", "KLC1", "KPNB1", "LRRC47", "MACF1", "MYCBP2", "NEK9", "NFKBIL1", "NOL10", "NOTCH2", "NUP214", "PIK3R4", "PLEC", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP4R1", "RAI14", "RBBP5", "RBBP7", "RCC1", "RPAP3", "RRP9", "SEC13", "SEC31A", "SEH1L", "SPTAN1", "SPTBN1", "STRN", "SYNE2", "UTP4", "UTRN", "WDR33", "WDR46", "ZDHHC13"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..f63b949c4d17562b0357cb4a70297790b39b82b5 --- /dev/null +++ b/msigdb_gobp/advanced/idx2term.json @@ 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sha256:877c7d2580233574dea6eb11b51ad60cb29a46884f1420f4b7177c5c9de1dc07 +size 573533 diff --git a/msigdb_gobp/df_merge.tsv b/msigdb_gobp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..523c22566794923b252e906b10cfded38db99c74 --- /dev/null +++ b/msigdb_gobp/df_merge.tsv @@ -0,0 +1,237 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Rna processing 197 524 8.356699426015593 6.449735677853646e-17 174.8398058252427 484.2694174757282 -1.2905738294783604 0.391342119918155 52.46042029044063 36.49980365222471 1.828301976615964 0.3458173073421634 1.0 0.0068220437938668 1.320595031442335e-06 2.0193699339065437e-13 7.3110874503169245e-22 +Cell cycle 160 537 5.843326646452117 5.116854310889952e-09 128.25485436893203 490.4490291262136 -0.5776536715114154 0.5660093263747779 43.00057123946773 50.423255384033105 0.915201334084853 0.3592548418815285 1.0 0.4878000604542405 0.0986472876491584 0.0156428779491058 4.10864041686379e-05 +Chromatin remodeling 61 92 4.56305704918015 5.041410849893069e-06 29.76941747572815 84.34223300970874 -1.1021115181861345 0.4129315637545374 11.29922828580962 7.331065887884421 1.3100736779036366 0.3661688957510465 1.0 0.2406407895411775 0.1180093146266414 0.0002516254438215 5.451293510346848e-07 +Chromatin assembly or disassembly 49 82 4.516249713909336 6.294443368748404e-06 25.4126213592233 75.33980582524272 -0.9675968019821958 0.4270574598510485 9.708100707247944 6.195916911165219 1.2627707803388504 0.3584932403699118 1.0 1.0 1.0 0.0043858065136258 0.0001575191310083 +Actomyosin structure organization 30 57 4.203531007385344 2.627831346257992e-05 15.91747572815534 48.65533980582524 -0.4229085702134161 0.575321431332321 7.057185654083857 5.8482132057634475 0.9475696966321172 0.3387054927389787 1.0 0.1501018175915273 0.4003567162826673 0.056604223796382 0.0033547161428921 +Regulation of rna splicing 42 88 4.161166859329215 3.166256291620151e-05 27.91990291262136 86.5121359223301 0.1323494025528259 0.5572910110956871 9.72639747067558 5.208502039558804 1.4178017247437722 0.381677869420044 1.0 0.4847391385004878 0.1443148752822858 0.0056594767783756 0.0021900378225429 +Regulation of mrna processing 49 90 4.108835210960406 3.976596898414009e-05 28.216019417475728 85.92718446601941 -0.2228919145260391 0.5576962459005645 10.340533670084309 5.761399745220316 1.278825309378284 0.3629423837638368 1.0 0.1250660932411784 0.0343021791505057 5.490077039549716e-05 0.0003627226478738 +Regulation of microtubule based process 30 77 3.821445659973198 0.0001326716499225 21.696601941747577 67.49514563106796 -0.5289321764667916 0.5698734240027278 8.753511811594498 8.269283185153798 0.906072407874556 0.3360791280875883 1.0 0.0627348303600114 0.1098971615885531 0.0395795689386441 0.0093202547381029 +Protein dna complex subunit organization 48 83 3.799499709056867 0.0001449884824922 24.73058252427185 73.4368932038835 -1.0690252759616734 0.4123846936316252 9.209679197605167 6.582810659062025 1.2041999827125236 0.3580535087398417 1.0 1.0 0.8313477677603678 0.0321416521107014 0.0001634419860872 +Ribosomal large subunit biogenesis 21 61 3.791895735154832 0.0001495016833232 27.936893203883496 57.978155339805824 -1.4029915310497645 0.3151876370658045 9.730639132175924 2.8671234011163116 1.5412102637359888 0.3569411110995745 1.0 0.2919842266274133 6.0437195681422445e-05 4.891003477997653e-05 2.6910988230960684e-08 +Spindle organization 39 90 3.641380966931646 0.0002711795019192 21.694174757281555 82.90291262135922 -0.2324189206855917 0.6756376156992406 9.03706848724996 8.998127705042224 0.6969293190208553 0.3015206527054129 1.0 0.5779929548395715 0.0915228676269577 0.0105640004857693 1.185440212339988e-05 +Nucleosome assembly 19 35 3.637047922354297 0.0002757806370852 10.776699029126211 31.87864077669903 -0.8198856419800098 0.3925620785099645 4.645035012638746 1.7926034917754707 1.280732376051939 0.3407527400770979 1.0 1.0 1.0 0.0033856845593825 4.711144425192826e-06 +Mitotic cytokinesis 18 39 3.624023593865846 0.000290055128165 8.66504854368932 32.87864077669903 -0.1738025196816203 0.6836296401331128 5.004797867713804 4.207578702871942 0.6946865697158596 0.284019353548359 1.0 1.0 0.4793101444108065 0.0054413454682795 6.98000131723506e-05 +Dna packaging 42 90 3.615484521518832 0.0002997863878702 24.890776699029125 82.94417475728156 -0.7771235377726682 0.4780287482860481 10.00340778724449 6.723693076785934 1.1273794268642208 0.3574460334968389 1.0 1.0 1.0 0.0083611052962659 6.53813909022458e-05 +Nucleosome organization 42 62 3.6149154594707658 0.0003004456479265 19.320388349514563 54.31553398058252 -1.0994002314887954 0.3888348562484474 7.387293725516045 3.8670190541746976 1.306552643796158 0.3608458478023482 1.0 1.0 0.6535993732589802 0.0047173667803823 3.6316082684522178e-06 +Microtubule cytoskeleton organization involved in mitosis 26 79 3.603111487693229 0.0003144305828963 22.575242718446603 71.39320388349515 -0.5630220740774639 0.5876631756636552 8.742079282631003 7.228970332296823 0.7718748037623286 0.3298137368175803 1.0 0.4949062745628336 0.0465586731094984 0.0068359435862179 1.111219008743236e-05 +Regulation of microtubule cytoskeleton organization 24 60 3.548723429216265 0.0003871034329401 16.737864077669904 52.54611650485437 -0.4918573858492255 0.5618313122286518 7.280391493058923 6.905415734904272 0.9205694898307956 0.3347786154799659 1.0 0.1399625708529587 0.1443148752822858 0.0172267333203586 0.0021900378225429 +Regulation of mrna splicing via spliceosome 31 66 3.473151989951938 0.0005143839689725 20.90776699029126 63.19417475728155 -0.0284228947141631 0.5570393050560812 8.11843388838484 4.171815400572056 1.3006194329456693 0.3699711363352614 1.0 1.0 0.2171594264364444 0.001488693597177 0.0038532557542741 +Negative regulation of transcription by rna polymerase ii 59 150 3.4685789088162604 0.0005232188466046 42.310679611650485 135.2742718446602 -0.7099369853602402 0.5036222762960962 15.784519346322798 17.001570978351552 1.0238382991971715 0.3491512488129793 1.0 0.167649352049286 0.0319819723258084 0.0212921237427822 0.0377071488844765 +Positive regulation of cell cycle process 32 82 3.4410503805746337 0.0005794606288473 22.16504854368932 75.29854368932038 -0.4558899215174454 0.6193778075819192 9.091601893926258 8.395022670972931 0.718138470829754 0.3111629037008511 1.0 1.0 0.0829428562374244 0.0547095741281485 0.0001907563515794 +Protein dna complex assembly 26 56 3.428855228834643 0.0006061327516988 16.436893203883496 51.24514563106796 -0.9267326990650656 0.4238470124616283 6.483990595084039 4.520245797096684 1.135975592393791 0.351605579116064 1.0 1.0 1.0 0.0421567666761504 0.000615643272746 +Mrna transport 24 79 3.421559131827081 0.0006226318406594 22.820388349514563 74.85922330097087 -0.3243975063403491 0.6631560494995676 9.43741633253777 5.020307051554142 0.9410187854636848 0.3234443435490755 1.0 0.01739707211014 0.0007922112268717 1.8241828556412716e-05 9.931172179875656e-05 +Mitotic spindle organization 25 70 3.4020940765041625 0.0006687161409748 20.28640776699029 64.09708737864078 -0.5671718138134516 0.5757720997321847 8.370400328477055 5.944753031372747 0.7566412941218653 0.3245464693018565 1.0 0.4392448907866976 0.1074078448971524 0.0080161077363617 3.3673213232201734e-06 +Protein localization to cytoskeleton 14 25 3.379142934174057 0.0007271219333215 6.004854368932039 18.62621359223301 -0.2034314636470449 0.6523913962354377 2.980515321338466 3.5164098296843456 0.6969429501467459 0.2740820639430165 1.0 0.2412174988663298 0.0174347284732116 0.0023815307246603 0.0539791573859534 +Recombinational repair 21 64 3.3563494681148485 0.0007897870201878 18.133495145631063 57.94174757281554 -0.5906828721466427 0.5588279210260131 8.256162418523777 6.631163910662059 0.7781206096991465 0.3233040494655922 1.0 1.0 0.7676207758337857 0.2928426867112851 0.0124439949429485 +Actin filament bundle organization 24 50 3.350818523141694 0.0008057308651856 12.87621359223301 43.25728155339806 -0.388973678757527 0.5457621089982349 7.149697341208452 4.766572559950323 0.9610581057590272 0.3370436860999113 1.0 0.1185798153291669 0.1157235318918368 0.3451562603913688 0.0708444734382891 +Cytokinesis 29 71 3.299729419320308 0.0009677808888115 15.555825242718448 60.36893203883495 -0.2474193945248756 0.699161424345413 7.43347780518241 7.119970943627489 0.6500017095099754 0.2883096902501693 1.0 1.0 0.7457455865111695 0.0531589052536714 0.0003797584352914 +Cytoskeleton dependent cytokinesis 22 51 3.2930693891822083 0.0009910001383077 11.490291262135925 43.230582524271846 -0.1757908518340132 0.7056070461791165 5.600138947012474 4.93774216812886 0.656476305402377 0.2806513900857585 1.0 1.0 0.5815024054643041 0.020850364041304 0.0003140392241675 +Microtubule organizing center organization 20 51 3.240782359191971 0.0011920215455842 10.985436893203884 40.730582524271846 0.0531780861213523 0.6579413251048066 5.115632006755549 6.500017673649269 0.8024863779803786 0.3148854550379723 1.0 0.1349531687426338 0.1375179432078189 0.0421567666761504 0.0259933892636634 +Cytoskeleton organization 162 378 3.20412046263199 0.0013547577989416 91.83495145631068 330.06310679611653 -0.4794748970131311 0.5966388785018272 30.99321788867253 38.29587037051379 0.9691685104755584 0.3460104332871342 1.0 0.0596086928758689 0.0413834723457876 0.0020633715126998 2.655221091459189e-07 +Rna splicing via transesterification reactions 84 187 3.1796487531684696 0.0014745366622048 57.62378640776699 175.9247572815534 -0.5311319544097726 0.5586481823524154 19.183116495466795 10.962720088427156 1.3427529129902214 0.3667601092782501 1.0 1.0 0.016118415164565 6.625510331172058e-07 4.7702640007304386e-11 +Protein depolymerization 26 48 3.176582745750742 0.0014902127084772 15.58252427184466 42.25728155339806 -0.515077916196691 0.5460274366835767 6.236479389964319 3.6817340242855745 0.9933853458617032 0.347633775999864 1.0 1.0 0.2534337902681366 0.2248894951905195 0.0518246752698681 +Protein peptidyl prolyl isomerization 9 29 3.124217912629841 0.0017827837189841 5.805825242718447 24.152912621359224 0.2517409431057898 0.5902438884006979 3.2955051837407017 2.757763315973305 0.91993420852781 0.3179002106692878 1.0 0.1624541869963563 0.299132167535026 2.226475151073292e-05 4.177932068990829e-05 +Protein localization to microtubule organizing center 4 16 3.1229268879435974 0.0017906222268893 3.655339805825242 10.949029126213592 -0.0810316112102637 0.620107147835328 2.1116058470898498 2.551379605694838 0.7621589677381015 0.281806770500618 1.0 0.1583124314184509 0.0047719907059414 0.001514434021342 0.0261400621732643 +Ribosomal small subunit biogenesis 28 59 3.119746064794142 0.0018100700847434 23.733009708737864 53.97572815533981 -1.1372450493015922 0.3808999194200835 8.485085582916668 3.272330781206946 1.1326078966579582 0.3577333752424699 1.0 1.0 0.1536294983436044 5.482872994382433e-05 3.3813125352445264e-08 +Regulation of dna recombination 15 51 3.104663611646147 0.0019049553852106 15.62135922330097 48.728155339805824 -0.8981163288911409 0.4561579333207878 6.4831619171338115 4.303857323304839 1.059500744175216 0.3590615088473968 1.0 0.3867843928672034 0.0161267578271334 0.0029276643552518 2.1183635638671503e-05 +Regulation of spindle organization 10 23 3.0894448281361195 0.0020053094760428 8.053398058252426 21.097087378640776 -0.6600198990767471 0.5221307715854213 3.960614729524242 2.339050355417879 0.7415101117342239 0.3116055197937813 1.0 1.0 0.3329579057594876 0.0175572363686136 0.0033280295566654 +Mrna metabolic process 144 371 3.0724217809383383 0.0021232947228597 110.86893203883496 347.06553398058253 -0.7232045019832187 0.5326950406306814 35.40161130973389 25.24286069321385 1.22004992086953 0.3569452048515953 1.0 0.0796711819310809 0.0009404627845576 2.6369760662581105e-06 1.879651137382278e-12 +Dna recombination 35 110 3.0660391705219765 0.002169148956536 29.524271844660195 100.3495145631068 -0.7704915900651469 0.5020315146479875 12.10078602934711 9.447564783946987 1.0098469163121409 0.349436210100644 1.0 0.710396306271557 0.0977310673657089 0.0197004275225112 0.0001978881566554 +Positive regulation of cell cycle 35 95 3.0308961489337 0.0024382909655817 25.983009708737864 89.22330097087378 -0.4683288768709446 0.5972720453959773 10.285827872335956 10.088137837377191 0.7756338551199762 0.3219979128481357 1.0 0.67972075728327 0.0743498483830931 0.1105661619906644 0.0007866942374685 +Microtubule polymerization or depolymerization 26 47 3.0074788317093715 0.002634244702123 13.53640776699029 40.94174757281554 -0.315346847705747 0.6178667072501902 6.30080397926982 4.916931797901264 0.8711699043308604 0.3245766892141421 1.0 0.4135892767062017 0.286220375734718 0.4964084842421358 0.0375543397860269 +Mrna processing 121 280 2.992231680914947 0.0027694599964147 88.13592233009709 263.25 -0.6982944696053023 0.5337908346895109 28.05587301363253 17.292827094840185 1.2796292765958024 0.3521504653572549 1.0 0.0174165040814835 1.61257923094347e-05 1.021864861940233e-09 1.9126366862309265e-17 +Metaphase plate congression 18 36 2.951202927746376 0.003165388773517 10.851941747572816 32.978155339805824 -0.4816867383588764 0.6183948949825314 4.706937775232176 4.211289553572027 0.6566033259470259 0.302624924192852 1.0 1.0 0.0257983671639557 0.0050477757378366 0.0380767748489745 +Establishment of cell polarity 25 50 2.948251902528193 0.0031957654001038 12.951456310679612 42.69174757281554 -0.4152353574801083 0.5884779866117905 6.115599409018415 5.3657154948088674 0.8300316292561851 0.3176977254810399 1.0 1.0 0.1053672202985524 0.0238605378340429 0.0108058362651867 +Negative regulation of gene expression epigenetic 18 32 2.947876183056545 0.0031996519065615 11.016990291262136 28.733009708737864 -0.806550808498718 0.4360473550946566 4.911567747447838 3.974625545030212 1.0377777852152994 0.3378366068073082 1.0 1.0 1.0 0.0268343307746464 0.0184969351752434 +Rna splicing 106 241 2.926514275300859 0.0034278377401069 73.21844660194175 227.36165048543688 -0.5595293373386813 0.5630575519934683 24.43896398568791 13.966422466014652 1.2766368335479483 0.3596377513528329 1.0 0.2748174731699989 0.0010129759325518 1.148259974512211e-07 2.9402564968727213e-13 +Establishment of rna localization 28 97 2.872175146872907 0.0040765696151432 26.20631067961165 92.9878640776699 -0.3134441225712214 0.6799638859056713 10.497972942596022 6.039702646587415 0.8275463151770961 0.3147488064841811 1.0 0.0322097188794439 0.0026776167659618 9.679012456142817e-06 5.711544376186879e-05 +Poly a plus mrna export from nucleus 3 11 2.871212410029342 0.0040890066220466 4.407766990291262 10.111650485436892 -0.5196261095450095 0.5538302177620679 2.558772814190137 1.2471949864196257 0.7732835142869388 0.3144053171471688 1.0 1.0 0.0117676307173903 0.0006528604561368 0.0079931710216612 +Regulation of alternative mrna splicing via spliceosome 20 32 2.863597868187227 0.0041885939649504 10.609223300970871 30.575242718446603 0.1468114472042654 0.5502297177540902 5.108075880658377 2.6128265930148187 1.194088433027589 0.3536418549118582 1.0 1.0 0.3837477700803094 0.3389463545945907 0.2152607060175029 +Establishment or maintenance of cell polarity 19 75 2.8544598918607256 0.0043110074787264 19.138349514563107 62.88592233009709 -0.4954421418557319 0.5643078759854735 8.100268795382732 7.396476192866255 0.8242348714817936 0.3214293461737292 1.0 1.0 0.2407998196724879 0.0265909455331675 0.0019174310884928 +Negative regulation of dna recombination 7 16 2.8502388104455507 0.0043686414497301 7.456310679611651 15.764563106796116 -1.346673592820196 0.2739204325877042 2.859243905179029 1.1660265918956667 1.1980906976493717 0.3143617576051659 1.0 0.1499686155438198 0.2780273254227372 0.0462975654587087 0.0046837779345005 +Positive regulation of response to dna damage stimulus 15 44 2.831576794759735 0.0046319109354167 12.691747572815531 41.269417475728154 -0.380094294153298 0.6015133540380907 5.7119046059561125 4.841942225495303 0.7836615148171553 0.3107506561281884 1.0 1.0 0.6704329277271275 0.057151442142415 0.0082613470370876 +Regulation of dna replication 21 51 2.824325555451848 0.0047380232097307 13.669902912621358 46.84466019417476 -0.2685794564797169 0.6887530949934776 6.73404385139537 5.001470233459607 0.5994126617246615 0.2806579010888841 1.0 0.4447949641299413 0.3260913714049449 0.3339749440897829 0.0130822015798701 +Multivesicular body organization 8 19 2.821614980738285 0.0047782505220714 5.162621359223301 12.932038834951456 -0.0971930993891373 0.5562325489293669 3.2140862480694596 2.880338895656491 0.9556888562513028 0.322794112187141 1.0 1.0 1.0 0.1757094500446031 0.0160305095638712 +Non motile cilium assembly 11 18 2.812243488451867 0.0049197245983116 4.055825242718447 12.298543689320388 -0.1105006006002452 0.5897641537829882 2.2553690091685983 2.2242480600322576 0.8583119880066024 0.3022610415396294 1.0 0.0248568883498602 0.0128572972549699 0.0073420453855006 0.0101516407294213 +Muscle organ development 14 37 2.809943118125959 0.004955025651171 9.29368932038835 37.019417475728154 -0.0627857440879655 0.6287977556930611 4.2195406482363635 4.8225412922062585 0.8471283705142204 0.3206765328667718 1.0 0.2026710555234917 0.4993218645755348 0.6032321203707904 0.4486506971889199 +Negative regulation of mrna metabolic process 23 45 2.807865375365147 0.0049871070287887 15.78640776699029 45.30339805825243 0.4317654752348391 0.5186468695555119 6.004287279655988 2.910090931551649 1.3207774317424965 0.3775544483756486 1.0 1.0 0.1570603590829851 0.0082889882958465 0.060537194309539 +Peptidyl lysine methylation 15 42 2.793589416700547 0.0052126615660779 13.50728155339806 37.95631067961165 -0.9560976032697625 0.3935787500089191 6.2765896828565495 5.88300448144661 1.1987330399071316 0.3424952593277601 1.0 0.4717478376334574 0.3618471127152637 0.0393100053011915 0.023369786825729 +Alternative mrna splicing via spliceosome 20 42 2.7846384183868005 0.0053587443397928 14.009708737864075 40.728155339805824 0.0708159133159534 0.5694011596603432 6.451830696216548 3.032011011191426 1.225863726972057 0.3649890000258197 1.0 1.0 0.4688773052385803 0.4679524167182146 0.2007884256395009 +Chromosome localization 20 42 2.7820926530079886 0.0054009618571724 12.558252427184469 37.91019417475728 -0.5322948294494124 0.6061347153593358 4.855584799188019 4.658658601174394 0.6383867543432414 0.3048594930538508 1.0 1.0 0.0397455353834247 0.0113736206845105 0.0122284679651323 +Negative regulation of nucleobase containing compound metabolic process 112 304 2.777046584708158 0.0054855316221535 80.22815533980582 281.74514563106794 -0.559151426772921 0.5612734989398143 26.411904926376423 31.26655834289824 0.928169609768154 0.3336124466598036 1.0 0.1134026265164164 0.0173327423542063 9.042960212602897e-05 0.0018716884170919 +Dna strand elongation 8 22 2.773606186914908 0.0055438744281293 7.691747572815534 20.640776699029125 -0.499784468032256 0.5604522039536165 4.44542197745498 1.8945725697321116 0.8164354759185254 0.3239923617246357 1.0 1.0 0.0532804729840314 0.0135456883876511 0.0095095891823194 +Microtubule polymerization 15 35 2.76909656379159 0.0056211972345256 10.25 29.805825242718445 -0.3404683453071433 0.616200507050644 4.990099421154824 3.3284832909305075 0.8297571715540287 0.3179116035217096 1.0 0.3058671484100957 0.163965403057363 0.2724020163606622 0.0095202961329739 +Positive regulation of cytoskeleton organization 25 56 2.699342997277931 0.0069476529225618 13.235436893203884 47.70873786407767 -0.205437944853101 0.6155485550669894 6.976757985883583 5.653216402064078 0.8612276872814943 0.3258637695512297 1.0 0.4949062745628336 0.153547659061056 0.2505311226043684 0.2308627672169501 +Chromatin disassembly 10 15 2.693809029866103 0.0070640626176685 5.138349514563107 13.233009708737864 -0.4510091705790431 0.5468831593234595 2.8280469768167373 1.067652205971331 0.781624420467073 0.2917860820859268 1.0 1.0 1.0 1.0 1.0 +Actin filament organization 52 119 2.6876018910840127 0.0071967142057114 33.3373786407767 107.19174757281552 -0.6548822630722094 0.5259173767314493 13.266874615391323 10.883078066802844 1.089954436723279 0.3540477446849532 1.0 0.4684801650337546 0.6121715060337712 0.2604010792132137 0.02360449392572 +Positive regulation of double strand break repair 9 22 2.6791170737312053 0.0073816579774006 7.155339805825243 20.723300970873787 -0.3977232119732917 0.5667310992796963 3.6210208332489975 2.9223180014586956 0.7979304791375895 0.300855393352772 1.0 1.0 0.4418810858922499 0.1757490259102167 0.0074744155515412 +Regulation of centrosome cycle 9 20 2.678997994946866 0.0073842836033963 5.349514563106796 14.550970873786408 -0.4049270935814868 0.6062972703312597 2.936078680277183 2.518826978707793 0.7123951110518449 0.2953496296682568 1.0 0.1988423464133734 0.3588505448912167 0.0975810446671989 0.0664883963333954 +Mitotic recombination 2 9 2.673883334123581 0.0074978530388407 3.9223300970873782 9.20631067961165 -0.4587851381862327 0.5338755172143151 2.301073284354054 1.5960080603558673 0.7692771494187963 0.2947970781259315 1.0 0.1114073342812727 0.0228441699597423 0.0201545454959308 0.1093101132411038 +Heterochromatin organization 17 32 2.6720318161892065 0.0075393499714913 11.368932038834952 29.56553398058253 -0.8051113952980317 0.4415464530549671 5.11848030249524 3.907681811771425 1.0326695352230617 0.3409983099936596 1.0 1.0 1.0 0.0072425712702839 0.0066454613143884 +Maintenance of blood brain barrier 5 9 2.644777499641444 0.0081744648793424 2.650485436893204 6.808252427184466 -0.077880046151196 0.5477325470988852 1.6719196446993512 1.121125411676901 0.9179824405634358 0.3056830481168421 1.0 1.0 1.0 0.4627901258069825 0.1199524552735497 +Muscle structure development 35 105 2.6351556644319216 0.0084098705285013 20.79126213592233 92.5509708737864 0.0014536259301341 0.6464566495683531 7.910305516126998 9.341411300056407 0.7931862105947302 0.3124032629019018 1.0 0.2415854079896645 0.4442865157544482 0.0851419537462233 0.0826213053801505 +Spindle assembly 24 58 2.634948038516634 0.0084150164142124 13.939320388349516 52.56553398058252 -0.2518631650830641 0.6911909780461348 6.345528777056968 6.371056858289978 0.6662986117220093 0.3005995825651292 1.0 0.4251307382490726 0.0973635670841622 0.057151442142415 0.0082613470370876 +Regulation of spindle assembly 7 16 2.6156102742212624 0.0089068155082236 5.62621359223301 14.342233009708735 -0.5287105275865441 0.5471766926213967 3.05628307681741 2.089470333793606 0.7543087971094908 0.3072542033229641 1.0 1.0 0.2489059409173845 0.0051734340414022 0.012132108209414 +Regulation of neuron differentiation 7 25 2.612571318425649 0.0089863940748802 5.286407766990291 20.160194174757283 -0.0173168065481275 0.5555762040934534 3.9079840740523073 2.6196731362780623 0.963059918132658 0.3115826074576115 0.0106904668496287 0.0161886013519254 0.0915328142013738 0.2785455703445695 0.6191577527055335 +Viral transcription 8 20 2.608820721717467 0.0090854827769979 5.466019417475728 15.49514563106796 -0.4213656629457412 0.5309907893364965 3.17473501372791 2.3291057761844285 0.8793019302954951 0.3128432296751765 1.0 0.0187248462666395 0.0663348012473392 0.0878701351278624 0.0566259049269907 +Negative regulation of dna metabolic process 13 40 2.584442109611368 0.0097536676964091 14.271844660194176 42.189320388349515 -0.8579389252547172 0.4540456966065038 6.312561332597989 3.834321565573901 1.053411758138618 0.3513905589374693 1.0 0.3806666514303258 0.2461545823107236 0.0096851437103604 0.0074110088598373 +Regulation of gene expression epigenetic 23 46 2.5832648535525053 0.0097870158098989 15.145631067961164 42.99757281553398 -0.6213452597534623 0.4941237467893123 7.362866378033921 5.544392245405396 1.0060115618516408 0.3414214623449199 1.0 1.0 1.0 0.122409660214331 0.1506431916840714 +Chromosome organization 122 381 2.572214270353007 0.010105032932949 101.62135922330096 353.40776699029124 -0.718702440590963 0.5246431988621554 35.54447958854473 36.06801473947072 1.0234435411635794 0.3402503944183533 1.0 0.2230331297841216 0.0328085240268053 0.0005932415752738 2.0130157351035824e-06 +Chromatin organization 72 180 2.563949414890268 0.0103488626056089 52.36407766990291 167.0364077669903 -0.8338184832356997 0.4872591602777898 19.522416064710743 20.266935497862097 1.2005273628623492 0.3635274769886619 1.0 0.1917966827028815 0.0380564218296635 0.0004388582443531 0.0001502748064729 +Double strand break repair 28 97 2.552036550787642 0.0107095283045974 29.216019417475728 91.01941747572816 -0.5887636271388033 0.5412745100521845 12.156720770138554 10.731028038704476 0.8600470863921482 0.3253897066282242 1.0 1.0 0.2176233130136849 0.145850999752491 0.0295000757437074 +Response to estradiol 7 17 2.5506144412534484 0.0107533213425521 4.480582524271845 15.609223300970871 -0.1183336658454337 0.5504992412244947 2.9241398453943264 2.3974526081633196 0.8881612224001193 0.295018926126729 1.0 1.0 1.0 0.8161698151860872 0.424806821173486 +Negative regulation of mrna processing 9 23 2.541090721763672 0.0110507241378925 7.699029126213592 21.66747572815534 0.1748680804835885 0.5472984180526073 3.879457852865703 1.8456483684321656 1.0884740123370542 0.3440194219213014 1.0 1.0 0.0305060181117638 0.0045459864196389 0.0451666412494461 +Regulation of microtubule polymerization or depolymerization 15 36 2.5312267275713114 0.0113664349323567 10.66019417475728 30.9126213592233 -0.3829948425661994 0.5886512404104359 5.405504921599998 4.092040097262249 0.8934277957402973 0.3258483899780218 1.0 0.3092959809067388 0.1674383799538608 0.2790882191036065 0.0290363363180858 +Positive regulation of microtubule polymerization or depolymerization 8 19 2.529108007261633 0.0114352831103934 6.83252427184466 16.1626213592233 -0.5273268554468391 0.5327373956353316 3.4625051872511285 1.8734892741925848 0.8437933593243525 0.3170586167184577 1.0 0.1457663642848915 0.0390334649397651 0.0428394238879484 0.0182596420242621 +Inclusion body assembly 4 10 2.5050119882051503 0.0122447243048151 4.237864077669903 8.560679611650485 -0.191215540413469 0.5578219533808813 2.530728300133765 1.4206205140445218 0.8557163939365652 0.3010823193289838 1.0 0.0937235599037543 0.179062604831997 0.3916284783790085 0.0708751155690715 +Mitotic metaphase plate congression 16 33 2.504992851380652 0.012245386830832 9.305825242718448 29.24757281553398 -0.3533284630994189 0.6647090238596493 4.698033574231406 3.761954270591056 0.5827348957688853 0.2765384134940811 1.0 1.0 0.4017902994798545 0.0381586751774073 0.1079287008920704 +Negative regulation of protein containing complex disassembly 12 31 2.494575231820194 0.0126107990541446 9.116504854368932 26.82766990291262 -0.2608854682966653 0.62049019037374 4.589034991464878 2.8654133383813543 0.7779479915580095 0.2990094133587384 1.0 1.0 0.1367168788611213 0.2197757549869858 0.1015220158066131 +Positive regulation of chromosome organization 24 47 2.4741197386199425 0.0133564923188307 17.817961165048544 46.43446601941748 -0.6158791497458386 0.5469282616833588 7.32023182019562 3.597879156336772 0.8948240774267895 0.3486713472616769 1.0 1.0 0.2063668513530253 0.1601360082818727 0.0578385475189744 +Chromosome condensation 8 26 2.470709374554356 0.0134845356311195 8.347087378640778 24.398058252427184 -0.81785765326126 0.4024287790270713 3.6713818808038847 1.899615729282307 1.1192710525415783 0.3308896927741966 1.0 1.0 1.0 0.229635410858896 0.0018029983207632 +Dna dependent dna replication 30 81 2.469967459284172 0.0135125343250248 19.410194174757283 74.91990291262135 -0.2275452700298281 0.6663437318244265 9.168286039077042 7.878993331187947 0.7053776591921856 0.3003616599045983 1.0 1.0 0.7833372437305444 0.7329928761134852 0.0376662738210931 +Stress fiber assembly 14 32 2.468190947972641 0.0135797858734671 8.424757281553399 26.310679611650485 -0.2779731412419229 0.6016675408002273 4.513374804462153 3.375465810971965 0.7864072454347135 0.2990140476595311 1.0 0.3328373805982222 0.5557866832475982 0.6013160240942994 0.3704901337943955 +Rna export from nucleus 10 55 2.4617721645072868 0.0138252459253562 17.594660194174757 52.0873786407767 -0.6036049285350094 0.5709925531490766 7.313590928071707 3.8763830506878816 0.9106568000664242 0.3348507095575251 1.0 0.0508992589190798 0.0007740006296611 1.6505360395963788e-06 5.1052272328632354e-05 +Defense response to bacterium 9 19 2.4551712634106293 0.0140817482350312 3.934466019417475 15.111650485436892 -0.551236054195157 0.4320072568101572 2.403087911621471 2.752255949194843 0.9691919262351948 0.2862957875852304 1.0 1.0 1.0 0.1818828429938442 0.0709528715803979 +Protein containing complex localization 14 47 2.45148759590659 0.0142267089796472 10.444174757281552 42.963592233009706 -0.0116153883479753 0.7670638185904641 4.810414475465765 5.508258117064915 0.5374525581408421 0.2588999426869024 1.0 0.4611241633653626 0.3476177217996948 0.3675354992995684 0.1561013133064908 +Regulation of protein depolymerization 14 37 2.4423196337616035 0.0145932197006768 10.769417475728156 31.51456310679612 -0.3737621885852451 0.5792198071205835 4.7717551522978425 3.151094978956661 0.8519317566800833 0.3172358389153141 1.0 1.0 0.1570603590829851 0.1000934206736157 0.060537194309539 +Response to wounding 29 89 2.441028375488929 0.0146455039647033 14.859223300970871 77.98300970873787 0.2907833523091244 0.6653892827271913 6.777288412904535 9.76879332264166 0.7686640367654125 0.3260596058790733 1.0 0.4419616026060442 0.8040523678205572 0.2134135209926605 0.159144596054606 +Mitotic spindle assembly 14 40 2.4302214746191027 0.0150895989361747 11.441747572815531 35.199029126213595 -0.5014440160220135 0.6186245666004432 5.902032302139985 3.774492704180119 0.7280573056853152 0.3181343048207691 1.0 0.2742474624411909 0.4741193373633443 0.0749307774450376 0.0011040578639144 +Regulation of histone methylation 10 33 2.425459869858916 0.0152890059698538 11.776699029126211 30.398058252427184 -0.8497118174919834 0.4451944425104745 5.229086015729897 4.357985207015717 1.0209131214219809 0.3445937820602485 1.0 0.295480255529908 0.1536294983436044 0.0299011110954108 0.0569218260288664 +Regulation of double strand break repair via homologous recombination 8 27 2.423651016474897 0.0153653632361474 9.135922330097088 25.48058252427185 -0.5787753960162068 0.5238661778648168 4.22670323843679 3.357662104247022 0.8246310119070387 0.3182680040655833 1.0 1.0 0.4582375595260778 0.1943181120702743 0.0304236608893936 +Wound healing 24 70 2.4230338968896588 0.0153914904439489 11.9126213592233 59.99029126213592 0.1446120400866948 0.6484734112111603 6.210086996743008 7.840330320006731 0.7798797329713693 0.3108096826634549 1.0 0.6861003044969223 0.902035942728746 0.2134462314161423 0.1048812774524959 +Viral budding 6 15 2.419266716767375 0.0155518324610346 3.7694174757281553 10.4247572815534 -0.099137274932558 0.546627250987593 2.442093771902005 2.697836006106568 0.9674049787317632 0.3230189468870872 1.0 1.0 1.0 0.1410845222447507 0.0402069493791732 +Folic acid metabolic process 1 6 2.417660423164831 0.0156206467108468 1.91747572815534 7.140776699029126 1.2977645388348351 0.249592124826322 1.215987926650751 0.8615786924829095 0.8405378716662024 0.2600707347072601 1.0 0.066549445548378 0.1289666473793992 0.0448845799435813 0.1467539296032722 +Positive regulation of dna repair 12 34 2.4164283396454818 0.0156736110645829 10.8252427184466 32.19174757281554 -0.4565373870411709 0.5727830178402521 4.858537045514951 4.02415399712675 0.7794647960938688 0.3059066969439832 1.0 1.0 0.5645278149470376 0.1508588620289784 0.0074770103502822 +Histone deacetylation 11 33 2.412649487587754 0.0158370415922035 9.844660194174756 29.058252427184467 -0.4500218362799439 0.5782966563764567 5.0019555041118196 4.129752908094089 0.7740403517609691 0.3091932492209324 1.0 1.0 1.0 0.1329615522764283 0.3508942766396105 +Regulation of vascular permeability 5 8 2.406901553899241 0.0160885061220645 2.883495145631068 7.405339805825243 -0.2539181193924132 0.4877662965194773 1.8580758962927757 1.57753360128169 0.9510023640387432 0.299018398287362 1.0 1.0 1.0 1.0 0.6133911232276724 +Regulation of actomyosin structure organization 13 29 2.406220844810464 0.0161185174638345 7.286407766990291 23.203883495145632 -0.2757894615232619 0.5963295698697699 4.029082348573948 3.717863524971043 0.7872533355380259 0.2946992625075854 1.0 0.2989593653745743 0.5094066821340305 0.5304634559367691 0.2736111683812483 +Dna conformation change 48 144 2.3963997180627628 0.0165570234238754 39.0873786407767 132.7378640776699 -0.6973547116570994 0.5289559820017552 14.76686581973929 10.578611105129252 1.0166119696110798 0.3585146685001696 1.0 0.7232426124859228 0.4663360709054027 0.0045151877376765 5.7612863368037385e-05 +Positive regulation of innate immune response 13 31 2.396237821752127 0.0165643389057088 7.567961165048544 28.844660194174757 -0.1107130679558175 0.7348205654992915 4.721644307798464 3.146140435805998 0.5616267426415904 0.2581912530292878 1.0 1.0 1.0 0.2857899601566555 0.0036518848204098 +Nucleosome positioning 5 9 2.3955744468749995 0.0165943439613243 5.915048543689321 9.186893203883496 -1.4577623895477416 0.2033217018902848 2.116753960133439 0.5715955001389142 1.226441656392813 0.2824784359054791 1.0 1.0 1.0 0.0390924086837951 1.665940864684324e-05 +Mrna splice site selection 8 19 2.394584564035555 0.0166392060242608 6.313106796116505 19.45631067961165 -0.0882007901962953 0.6106662837845365 4.074729493463986 1.85009419350405 0.8768494806167952 0.3199572041194961 1.0 1.0 1.0 0.4888757324884423 0.0089325963600969 +Regulation of inclusion body assembly 3 8 2.393236519846626 0.0167004714236358 3.3058252427184467 6.856796116504855 -0.0930538662559062 0.5727311326957607 2.1095402914627046 1.2012846793169458 0.8450630575833225 0.3015763047873161 1.0 0.0711332726649859 0.1375212864755611 0.3110830097266777 0.0338099842169397 +Regulation of telomere maintenance 22 39 2.3931200414928275 0.0167057743719942 15.177184466019416 38.64563106796116 -0.5549641196000056 0.5757193682578697 6.8461004303102815 3.5032100868250593 0.8179346681191738 0.3321815361156814 1.0 1.0 0.5468718822386345 0.1329615522764283 0.094428031243587 +Maintenance of cell number 14 31 2.3864266212949423 0.0170130021488652 10.803398058252426 29.968446601941743 -0.5884662133928888 0.5584963996543092 5.522477292256744 4.648465089041957 0.7682966600028914 0.324890547380947 1.0 0.4279811411777856 0.673701145430139 0.1443444537491567 0.3127645641376552 +Negative regulation of ubiquitin protein transferase activity 4 14 2.378291840141214 0.0173930540801587 5.580097087378641 12.696601941747574 -0.5088829086701004 0.4586281594762058 2.729894195874838 1.339355049397188 1.0317785211822748 0.322235533653335 1.0 0.0937235599037543 0.0161297090986061 0.0852058322554232 0.0144964406909979 +Positive regulation of neuron differentiation 4 10 2.374962895768804 0.0175507143454147 2.441747572815534 9.097087378640778 0.1489217986910376 0.4752014853635246 2.2799260877069525 1.0636497261494449 1.0912419199569945 0.312731807854903 0.0044134954883629 0.0204019662414969 0.0718258186813318 0.3027256215831923 0.6517647575525387 +Midbody abscission 5 11 2.373785243355369 0.0176067877181145 3.4393203883495147 8.424757281553399 -0.3360710800098827 0.5386342770729817 2.2681217421375623 2.0917472348459825 0.8842729646944634 0.3164949847148881 1.0 1.0 1.0 0.0639524888435202 0.0470360579614364 +Mitotic sister chromatid segregation 36 93 2.365447672830597 0.0180082879393366 26.339805825242717 83.03398058252426 -0.5166788658598314 0.6040184232844363 9.169444190266534 9.049154371242343 0.7798564553977988 0.3207300360509135 1.0 0.5474081709152836 0.2072703928428452 0.0985723467704107 0.0049462414196955 +Peptidyl proline modification 16 37 2.357631811674536 0.0183919245389234 7.95873786407767 32.38106796116505 0.6521103584457676 0.5266525958057561 3.2591538539789924 3.194797169860135 0.931894104733149 0.3508680261875629 1.0 0.2145132052110039 0.3837477700803094 0.0001746412301643 0.0005183300980067 +Rna stabilization 7 26 2.337476085349426 0.0194144430020541 9.359223300970871 27.37621359223301 0.4792302048577673 0.5262457931829767 4.411160534464403 1.6856669427134765 1.0994939820726763 0.3614208213771557 1.0 1.0 0.3837477700803094 0.0315918233013491 0.0888810791636133 +Maturation of ssu rrna 19 40 2.336017468038236 0.0194903311495253 16.638349514563107 35.70388349514563 -1.131335162864313 0.3627423636730687 5.844073023919836 2.612457918278519 1.0565309172845814 0.337115899685484 1.0 1.0 0.3837477700803094 0.0001746412301643 3.919573774442413e-07 +Protein containing complex organization 229 617 2.3284315897161982 0.0198891978779991 110.5752427184466 543.3398058252427 -0.4959936242473367 0.6498574895072522 38.74952763494516 40.5605273222788 0.6654039468146281 0.3553075017263935 1.0 0.7606869194007426 0.4748259601516686 0.3804274760316289 4.021826044529657e-05 +Sarcomere organization 4 9 2.3259899341307726 0.0200190876763413 3.1820388349514563 8.04126213592233 -0.3719129724502946 0.5316742734915499 1.8003148911314684 0.9782818102248436 0.8178428127973492 0.2865039879058722 1.0 1.0 1.0 0.1003847610205272 0.2914565107291916 +Endosome organization 16 39 2.320072374411984 0.0203369624855207 7.677184466019417 28.553398058252423 0.1938836583639464 0.5716653902061297 4.453117576534254 5.135972800603594 0.9660014731386156 0.3290604174592388 1.0 1.0 0.5190509805854646 0.0349006731083518 0.0095202961329739 +Protein dna complex disassembly 9 15 2.317905370041349 0.0204544645410849 5.271844660194175 13.395631067961164 -0.4391653954766292 0.5552496021812113 2.9925284784469715 1.0480126082237498 0.7889106203754103 0.2998214654045657 1.0 1.0 1.0 1.0 1.0 +Mitotic cytokinetic process 5 13 2.310904520970361 0.0208381292949959 4.065533980582524 10.652912621359222 -0.4567641788257172 0.5422434827133252 2.7418150844984392 2.237894351457929 0.8119147800034832 0.3090959843592445 1.0 1.0 1.0 0.1082353444632946 0.09905667817091 +Non lytic viral release 5 10 2.305969749560118 0.0211123226867266 2.7985436893203883 6.696601941747573 -0.3541879867879425 0.5160730006790809 1.7434197550406505 2.0235717981164276 0.9013387621881428 0.3047161752821017 1.0 1.0 1.0 0.0448845799435813 0.0280386150660574 +Muscle cell differentiation 24 73 2.3049389783330496 0.0211699912094607 13.58495145631068 61.83980582524272 0.1726021306033935 0.6436549160646058 5.702585578419399 5.973937567415945 0.8016706101837519 0.3164898778535634 1.0 0.6440859247507438 0.6089059923481928 0.0322025805982828 0.1381298295429051 +Centrosome duplication 10 24 2.3043173268881185 0.0212048370164359 5.371359223300971 18.021844660194176 -0.274564440315208 0.6504291330120867 3.1245124042260586 3.343158278759834 0.6774540520128062 0.2854947284148746 1.0 0.2849410889163232 0.4895400608205746 0.2327516588823357 0.1130329164300312 +Regulation of actin filament bundle assembly 13 30 2.303449874366927 0.0212535443565378 7.788834951456311 24.216019417475728 -0.3105593870428843 0.5775526615040627 4.215847540806247 3.185134719927712 0.8287181843809058 0.3066297262981273 1.0 0.3092959809067388 0.523802502209471 0.5525895141700823 0.1581267151757794 +Negative regulation of rna catabolic process 14 32 2.3031744320102003 0.0212690307778975 11.186893203883496 32.42718446601942 0.419853700893663 0.5432159718224696 4.924332595678975 2.3133296381008863 1.0980554146273172 0.3596399931743501 1.0 1.0 0.4363210249842685 0.0135656277048388 0.06212243803085 +Cytoplasmic microtubule organization 11 20 2.293199132800892 0.0218365430609384 5.54126213592233 16.283980582524272 -0.4057129541840621 0.5157598295914038 3.1454615725041517 2.514894597110268 0.9601707502093324 0.3182361626257836 1.0 1.0 0.3837477700803094 0.3389463545945907 0.0888810791636133 +Meiotic cell cycle 12 58 2.28953640773886 0.0220482050467563 12.92233009708738 55.842233009708735 0.0993622526463597 0.6833673987108698 5.626634511843725 6.778883751516931 0.7601304899640036 0.3087139543797219 1.0 0.5266103228678283 0.0609578144277862 0.0779948213476583 0.0328649875506932 +Positive regulation of histone methylation 9 24 2.2858389729598545 0.0222636807440919 8.03640776699029 20.51941747572815 -0.6134872863838615 0.4867520249693898 4.074683227754228 2.8107131476779252 0.9297606582376562 0.3248564748697674 1.0 0.1948770046367652 0.3524722176470324 0.0222384769528305 0.0190396454378568 +Regulation of mitotic spindle assembly 6 14 2.275408636121584 0.0228814277913893 4.614077669902913 11.978155339805824 -0.3717630801903488 0.6003900582375971 2.8325596290669353 1.9662216724443695 0.7103118581058366 0.2930801689286371 1.0 1.0 1.0 0.0179536348510701 0.0236194052560011 +Cortical cytoskeleton organization 9 26 2.273327508452064 0.0230064510152403 9.842233009708735 24.211165048543688 -0.7916731875438747 0.4696608264720133 4.593353457392695 3.2881918190364745 0.9620922568600312 0.3536881623698881 1.0 1.0 1.0 0.1182182962859381 0.0023236798464153 +Positive regulation of nucleobase containing compound metabolic process 129 436 2.2708817256134197 0.0231541388053833 112.16504854368932 393.94174757281553 -0.6915861110834464 0.5265563055807637 39.057735975869754 40.823578576844234 0.8771300612745363 0.3346544075288122 1.0 0.4869708115502321 0.154856568576054 0.1375529758050179 0.1894866858632866 +Histone h2a acetylation 3 11 2.268718462747797 0.0232854521183931 2.8907766990291264 9.237864077669904 -0.1564128399144135 0.5422783789089188 2.1064423554274203 1.7478761872601674 0.8716824274276185 0.2832015690604444 1.0 1.0 1.0 0.1003847610205272 0.020271757680103 +Positive regulation of response to biotic stimulus 14 35 2.266873816595681 0.0233979351432154 7.951456310679611 33.12621359223301 -0.0617604819007783 0.7198825896728834 4.217689609981926 3.795576402369345 0.5941180389571624 0.2641289791306457 1.0 1.0 1.0 0.3933256130807443 0.0049769573893231 +Regulation of microtubule polymerization 8 24 2.2610443401714213 0.0237565114912905 7.679611650485437 20.97087378640777 -0.3943368841777991 0.5778467268266472 4.127138674141253 2.3532927176911267 0.8690879467965045 0.3181286055300483 1.0 0.2067156970649581 0.0774589481602222 0.1077051615751485 0.0256439269364036 +Positive regulation of histone modification 12 43 2.25787760632183 0.0239532911112632 12.330097087378642 38.21844660194175 -0.5091665790710859 0.5619556418837895 5.464605173231814 4.259865706730865 0.8491061571437442 0.3326022301523977 1.0 0.3361355940595682 0.5601787468810149 0.146300328738182 0.2175611039015379 +Mitochondrion morphogenesis 5 11 2.2523291442749427 0.0243014797265637 3.424757281553398 9.91019417475728 -0.0351473409841172 0.6209559408415242 2.060179247861886 1.2518696546362469 0.7829362304544956 0.295241688491213 1.0 0.0892490045576324 0.0146091852998709 0.0779048373986419 0.0624183143373935 +Protein localization to cell cell junction 4 9 2.245747104601852 0.024720211136213 3.470873786407767 8.342233009708737 -0.5942300283334737 0.4496405075073661 2.036469964450486 0.9357323408259656 0.888856224176567 0.3007607459983228 1.0 1.0 1.0 1.0 0.6133911232276724 +Tissue morphogenesis 23 83 2.2442776232941126 0.024814544366758 19.104368932038835 70.35922330097087 -0.4005968516206312 0.5846394328690956 8.031568801752694 9.898371317370572 0.7697612574989432 0.3110634910530838 1.0 0.2882676887574082 0.5192108727649948 0.8330365823164889 0.4980949063333011 +Mrna export from nucleus 7 40 2.244135473117347 0.0248236862025412 13.266990291262136 37.978155339805824 -0.5392925336847666 0.5692591516537554 6.291586126740776 3.3533070903048774 0.9023833533663655 0.3298426418906709 1.0 0.2412174988663298 0.0021648846033271 5.995306889020075e-05 0.0003251864982136 +Negative regulation of cytoskeleton organization 20 54 2.238361219463852 0.0251975088391391 13.390776699029129 45.157766990291265 -0.2358333962179944 0.6494686080786257 6.430752298517954 4.740024053037745 0.8109977411434409 0.3172827394803355 1.0 0.4743715197669595 0.3653872604900754 0.6221619398622211 0.1023053488119434 +Response to heat 14 38 2.237430249402958 0.0252582333397914 9.308252427184469 36.31310679611651 0.0210888904704707 0.7302355793773286 6.400062943741517 4.228489029669047 0.6343994197175411 0.2764736963799276 1.0 0.3058671484100957 0.5190509805854646 0.1079193974753917 0.0270449321241776 +Microtubule cytoskeleton organization 77 189 2.2373349514087115 0.0252644564944766 43.83009708737864 164.70631067961165 -0.2059463215733804 0.6768554367174028 16.009713889558597 20.221195718646996 0.7870016820046382 0.3160833319212116 1.0 0.0270025533562664 0.0171344386926256 0.0120975678169601 0.0004286458259667 +Regulation of epithelial cell differentiation 7 21 2.228286347709068 0.0258614261494236 6.077669902912621 15.444174757281552 -0.6819616761732761 0.4867055413191141 3.20327296330545 2.3891522745147737 0.8727739258050476 0.3301459773130544 1.0 0.295480255529908 0.1536294983436044 0.096283450418097 0.0569218260288664 +Positive regulation of double strand break repair via homologous recombination 6 17 2.227721105888069 0.0258991186834407 5.165048543689321 15.898058252427184 -0.2834313886787504 0.616435087350389 2.829618271207321 2.421444669586483 0.7115713828617523 0.2798412031619757 1.0 1.0 0.2921659829416722 0.0536128505953338 0.0012811473170246 +Regulation of ubiquitin protein ligase activity 4 15 2.215937914581815 0.0266957544458574 5.614077669902913 12.866504854368932 -0.2319963290066109 0.5431006060295966 2.8843561772212154 1.3216437314530178 0.9381549673371022 0.307975416482431 1.0 0.0981765691424607 0.0177148463510605 0.0927037920539492 0.0172333771485565 +Protein sumoylation 5 14 2.21348812685842 0.0268640109117459 5.449029126213592 12.063106796116504 -0.7734736807425795 0.4586185817127698 2.6640038538133246 1.9647124986080844 0.7876287884147899 0.3088433530316668 1.0 0.1908924307699622 0.3460310778663031 0.6568914933439602 0.6269975513332796 +Peptidyl lysine modification 33 111 2.213272675928493 0.0268788522354852 26.053398058252423 97.08009708737865 -0.481071266966831 0.5673299852772474 11.608377586931471 14.49358384962491 0.9098365591307236 0.3406765740192053 1.0 0.2272036705646787 0.2337148002162704 0.0700952533606135 0.0387867951428488 +Monocyte differentiation 3 7 2.211006484518636 0.0270353880182501 2.4733009708737863 6.400485436893204 -0.2203280141796344 0.5896278873638742 1.655167189132155 0.8460644225290821 0.7934097859349585 0.2937271932971729 1.0 1.0 1.0 0.3606019508791212 0.0544656750173612 +Epithelial cell differentiation involved in kidney development 4 7 2.204845973016908 0.0274649047719537 2.5776699029126213 5.711165048543689 -0.249983434786031 0.5312622137935125 1.6358503052336422 1.1560611071386278 0.904943053758616 0.3066169752623464 1.0 1.0 1.0 0.4888757324884423 0.1423023069394473 +Cell differentiation involved in kidney development 4 7 2.204845973016908 0.0274649047719537 2.5776699029126213 5.711165048543689 -0.249983434786031 0.5312622137935125 1.6358503052336422 1.1560611071386278 0.904943053758616 0.3066169752623464 1.0 1.0 1.0 0.559801856438838 0.2160393117631846 +Ribosome assembly 17 52 2.203804568120864 0.0275380911868305 19.055825242718445 47.779126213592235 -0.7035456798868047 0.4889990460878361 7.9427129727517 2.4439843351936754 1.0202647585816325 0.348323682133052 1.0 0.2486824788491954 0.1106573079891401 0.1696751373461712 0.001821375794174 +Positive regulation of protein polymerization 10 31 2.2032609384973605 0.0275763624219678 8.29126213592233 29.067961165048544 -0.1407148677954534 0.5820281683314947 5.027364087585942 2.9976111392542504 0.9226797177142148 0.3196707976657912 1.0 0.2919842266274133 0.1502138999638582 0.2458623134324377 0.0534436555525331 +Escrt complex disassembly 5 9 2.203000833269486 0.0275946899112584 2.95873786407767 6.334951456310679 -0.1803367519990314 0.5335470166401733 1.8409438164072944 1.573272437530148 0.9378304399004606 0.3132763636446821 1.0 1.0 1.0 0.2199219252501269 0.0823369674942117 +Regulation of cytoskeleton organization 65 155 2.197696130121789 0.0279707675181786 40.179611650485434 135.42233009708738 -0.4417351969096031 0.5790301794162391 15.770402776488616 15.738959342109927 1.0277026860444949 0.3450236295087346 1.0 0.585272666124266 0.3498157277907959 0.1098549674963848 0.0034864212195299 +Intermediate filament organization 3 7 2.194275979005876 0.0282155752536883 2.2233009708737863 6.087378640776699 0.2623037643723794 0.4180828699239641 1.2535931954616677 0.8315011120555454 1.1682966764755611 0.3104064442188157 1.0 1.0 1.0 0.2759666252930612 0.0228394808772788 +Suppression of viral release by host 2 8 2.188264240505485 0.0286503600897021 1.808252427184466 4.900485436893204 0.1546907670699923 0.5284647645806793 1.5071447493534975 1.2036755027030055 0.9418636473359748 0.3135183162225088 1.0 0.0020655426456597 0.0080257871552124 0.0448845799435813 0.0280386150660574 +Protein localization to microtubule 5 9 2.1880512105824264 0.0286658722488613 3.0679611650485437 7.638349514563107 -0.1760805321628245 0.6165324726587809 1.8182576527257437 1.0761244713505824 0.7406245439924137 0.2836248801088259 1.0 1.0 1.0 0.3445026949300507 0.5726791496550556 +Negative regulation of mrna splicing via spliceosome 6 16 2.187850382560036 0.02868050252722 6.087378640776699 15.199029126213592 0.1078323316448317 0.4870213286066137 2.88823121239329 1.0677073837920623 1.2108018519405566 0.3438522963849697 1.0 1.0 0.0146091852998709 0.0779048373986419 0.236286730772413 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 5 17 2.17857142872473 0.0293635205971947 4.094660194174757 11.37864077669903 0.002182340961636 0.524688059582186 2.6764471869861683 2.8680242678638037 1.0149817540499388 0.3268991027874168 1.0 1.0 1.0 0.1934880896161839 0.2160393117631846 +Humoral immune response 4 14 2.1774976819036818 0.0294434545799007 3.342233009708738 12.41019417475728 -0.092695361541128 0.5305179078274306 2.2548465308630896 1.1338537093209262 0.9212427562429062 0.2899410900952026 1.0 1.0 1.0 0.6482306364536417 0.6141103665774779 +Tissue regeneration 3 7 2.1751987828882924 0.0296152233571644 2.237864077669903 5.939320388349515 0.0058255705017962 0.5074833040137664 1.523831177412142 1.1756871670759337 0.9998757083281912 0.3118745730683118 1.0 1.0 0.299132167535026 0.2205441276431149 0.2554523730097116 +Microtubule organizing center localization 4 14 2.1744831547350554 0.0296688691367419 4.303398058252427 13.54611650485437 -0.0465627605825851 0.6388422063488598 2.686298949378703 2.8507041313821126 0.7340917646690812 0.2833237578025446 1.0 0.1373006943976843 0.2562935091164666 0.5256573230515567 0.0560616912320164 +Ribosomal large subunit assembly 8 23 2.172325867271661 0.0298310922601667 10.949029126213592 22.00242718446602 -0.9337020047554596 0.3779626044413149 4.209884811412927 0.9412313418456992 1.116757197008177 0.339166817285299 1.0 0.1157751708195439 0.0246740936940832 0.1243944683174773 0.0010422272070108 +Intraciliary transport 2 9 2.169615588250005 0.030035979484388 2.104368932038835 6.322815533980583 0.2445749073276863 0.5480110908811205 1.3150659254048809 1.596465706609464 0.873230914700662 0.2954620725820503 1.0 0.1624541869963563 0.299132167535026 0.2205441276431149 0.2554523730097116 +Regulation of response to reactive oxygen species 1 11 2.1651587892829576 0.0303755270905419 2.179611650485437 7.944174757281553 -0.0623480553155879 0.4810439073108864 1.7381420290822969 1.2692364681879964 0.9814591255351324 0.2740586473575921 1.0 0.0060718409625537 0.0228441699597423 0.1162426898263886 0.3280048671308403 +Microtubule nucleation 10 17 2.1544056710406947 0.0312083722341149 5.427184466019417 14.155339805825244 -0.3072912097217509 0.6107739132404288 3.01405104854809 2.1632736858455535 0.7577787396947864 0.302159157409364 1.0 1.0 1.0 0.5914976917658876 0.0962848984941054 +Blood vessel morphogenesis 27 87 2.153464961314409 0.0312821549665769 16.385922330097088 77.21116504854369 -0.0973321885149326 0.6747953299436705 6.598329876492682 9.741890907235984 0.7122561449451958 0.2968219097091266 1.0 0.2155749187316888 0.6269058511281315 0.1801252069763968 0.4276703965035321 +Regulation of telomere capping 3 9 2.152176812922439 0.0313834311347642 3.3810679611650487 8.737864077669903 -0.2381462290924099 0.5898539767790975 2.217085208246178 1.9864158338626547 0.7665598077309258 0.2878084978533924 1.0 1.0 0.2186221342412543 0.022497237178051 0.0312662716526952 +Negative regulation of intracellular transport 5 21 2.1466275463200097 0.0318229450954246 5.871359223300971 17.25485436893204 -0.4323519785831102 0.5282548875744855 3.2284318080021124 2.5648105454655705 0.8691455606043381 0.3102675601363743 1.0 0.1868885334554594 0.339526513295544 0.0034531211085642 0.0153479918417224 +Striated muscle cell development 6 13 2.144325398143275 0.0320068231429111 3.5145631067961167 10.861650485436892 -0.20361485068932 0.6176759848794741 2.06620555406489 1.4271246107255664 0.7428816625149436 0.287775274729655 1.0 1.0 1.0 0.229635410858896 0.5446047019091178 +Cytokinetic process 8 21 2.1424266524543616 0.0321591650795931 5.888349514563107 17.194174757281555 -0.4497105427679648 0.5839051258381596 3.465104853367335 2.5978267707114235 0.7411674093854904 0.3012090629808677 1.0 1.0 1.0 0.0697809861326579 0.0396063215160503 +Kidney epithelium development 6 14 2.1408832570186016 0.0322834536605536 4.12378640776699 12.104368932038836 -0.3171125298255884 0.5504830876358152 2.494015601085131 2.46947978874012 0.8498795708250578 0.3069758915159226 1.0 1.0 1.0 0.8767997114622359 0.7838922927404748 +Regulation of rna export from nucleus 2 10 2.1378827239300464 0.0325262627385514 3.638349514563106 9.516990291262136 -0.1000785089757399 0.5618225409730601 2.180626344993646 1.1308569952010117 0.8835605969950311 0.3064943312074072 1.0 0.0573151884822011 0.1116045715736199 0.0027195691326621 0.0182159139614431 +Extracellular matrix assembly 2 6 2.1338505039759688 0.0328550202147246 1.5655339805825244 4.844660194174757 0.2441705053919552 0.5544481976271249 1.2436543616195848 1.393516760646209 0.914170317979426 0.3133445413688597 1.0 0.0060718409625537 0.0228441699597423 0.0201545454959308 0.1093101132411038 +Rrna metabolic process 68 186 2.120844979717343 0.0339348500805192 79.82281553398059 172.23300970873785 -1.6812156795693456 0.3379083897497131 24.180152412951102 10.313017397195509 1.8165576220515032 0.3675576941020368 1.0 0.358653007095521 0.0036009286451109 1.586715716108656e-08 1.0719828714417203e-11 +Histone methylation 16 54 2.1196183333316863 0.0340382451148206 16.405339805825243 49.45145631067961 -0.8481822700059978 0.4155946596352777 7.519442154935778 6.776606878946171 1.1983596045148888 0.3408419918272136 1.0 0.50487672715324 0.4072471672288124 0.0601854238699996 0.0443686098043893 +Protein transport along microtubule 2 6 2.112374872751954 0.0346543084587585 1.5946601941747574 4.288834951456311 -0.0111075410171745 0.4975104992993215 1.1837371424417156 1.2094175770475637 1.0712803318081294 0.3237118734410871 1.0 0.0479914252810258 0.0938999510605359 0.2199219252501269 0.0823369674942117 +Ribonucleoprotein complex subunit organization 45 127 2.10752762336662 0.035071869849903 43.8252427184466 122.55339805825244 -0.8012833124398862 0.4916443883443009 14.223716816877324 6.529586369896487 0.9290050468813984 0.3383094355243821 1.0 0.5758772071007734 0.0900640862105839 0.2510321537534521 3.273135812951103e-06 +Regulation of nucleobase containing compound transport 2 11 2.106808034416081 0.0351342227845901 3.7936893203883497 10.235436893203884 -0.0755175695248488 0.5839883836345571 2.245526076399216 1.3147433406725342 0.8376392375067842 0.3001788353881168 1.0 0.0619434524836269 0.1203280145079081 0.0034718672031755 0.0228394808772788 +Endothelium development 11 26 2.100713982260737 0.0356660811781015 6.737864077669903 24.12378640776699 -0.4291122725993125 0.5414550878232368 3.793098395485648 2.8619901475832856 0.8514678901254557 0.3048037960076107 1.0 0.0496758524768897 0.1605058634275269 0.1039724394002597 0.1445179295897953 +Spliceosomal tri snrnp complex assembly 3 10 2.096581821137624 0.0360306099141198 4.150485436893204 10.900485436893204 -0.3379806169509086 0.633344930235145 2.466607031893795 0.7121005146689612 0.6299062479256886 0.2712568220053767 1.0 1.0 0.1203280145079081 0.2759666252930612 0.1297945989547683 +Protein localization to membrane raft 1 5 2.09204317347344 0.0364346538041902 1.4077669902912622 3.9466019417475726 0.6995898605489175 0.3935219612382615 1.1611585543864895 0.8516478070075068 0.9757696678130928 0.2997431266177076 1.0 0.0338360956076009 0.0019368511639724 0.0115925044366013 0.0423042030727838 +Positive regulation of dna dependent dna replication 5 8 2.089268313887329 0.0366835770090854 2.104368932038835 5.308252427184466 -0.0451029964534636 0.5304800246160674 1.3260937379209767 1.085933831223192 0.9590241497998035 0.3064788302511712 1.0 1.0 1.0 1.0 0.1467539296032722 +Histone h3 k27 methylation 3 9 2.085032469655269 0.0370663532959567 4.356796116504855 7.691747572815534 -1.379115130968022 0.2197697774511291 1.6812435951975209 1.318144420380235 1.0709765358431076 0.274485257004507 1.0 1.0 1.0 0.0779048373986419 0.0120515986398723 +Rna localization 31 121 2.078449255403534 0.0376680000892117 35.41019417475728 116.41504854368932 -0.4611740850325216 0.6420673550901911 13.31978574134381 6.603916662777147 0.831302028365655 0.3210194663955101 1.0 0.0556730506346275 0.0078063040086141 0.0001129450637435 0.0010010113260162 +Embryonic morphogenesis 21 89 2.0716581076344536 0.0382973367553889 18.9004854368932 73.58252427184466 -0.2930460993923443 0.6859258672917905 8.901963335167231 10.546498311655885 0.5639975754441425 0.2675861505824237 1.0 0.1117375316931691 0.3089043722764526 0.5777393521724415 0.2152928601971347 +Plasma membrane repair 5 10 2.068191134951104 0.0386220535463697 2.9563106796116503 7.16747572815534 -0.3921405121287362 0.5338017968845418 1.86251577971618 1.863968633036741 0.8385379980748517 0.2932088320798485 1.0 1.0 1.0 0.0105546488673461 0.0120515986398723 +Cell cell junction organization 17 45 2.06651995958439 0.038779409745401 14.29126213592233 41.99271844660194 -0.633000005861134 0.52282289075606 6.5480020935184235 5.639875832513034 0.9392962903313726 0.355847184778423 1.0 1.0 1.0 0.3563462315017516 0.1458006163513331 +Regulation of actin filament organization 31 76 2.06193910829466 0.039213533588075 18.41747572815534 66.56067961165049 -0.2922925132099168 0.5909006286626618 8.47643709709813 7.12602964961936 0.911409569076438 0.3306612335990657 1.0 0.6295124465651736 0.5874091158046593 0.5460682041097351 0.1780895056531652 +Regulation of ubiquitin protein transferase activity 6 29 2.058286963480947 0.0395625948645692 8.70388349514563 23.31553398058253 -0.2638433633428079 0.5389953735662216 4.578303037684729 2.424080539593838 1.0747712600983823 0.3338119076531364 1.0 0.1988423464133734 0.0718258186813318 0.3027256215831923 0.0664883963333954 +Protein polymerization 29 92 2.05813748828384 0.0395769372667955 20.648058252427184 79.22815533980582 -0.0389331724937979 0.6564498315595959 10.341025897751436 7.507690781396995 0.884459978126196 0.3320308777285349 1.0 0.2807980004527436 0.3477480618641206 0.423884459340055 0.016194659422455 +Ncrna transcription 7 27 2.054402941211027 0.0399367086380619 11.74271844660194 26.3373786407767 -1.0619661354840784 0.3623331146466154 4.464185461352277 2.793936034587948 1.0007305555093453 0.3217402445131062 1.0 0.2412174988663298 0.0174347284732116 0.0117617677343892 0.0183758279429038 +Positive regulation of supramolecular fiber organization 22 51 2.053263358451699 0.0400470425125725 11.898058252427184 42.94660194174757 -0.179098978629616 0.5967777713554824 6.786572702413961 5.180908109738063 0.8576881277686925 0.3136528458896333 1.0 0.4637995473310806 0.3511849676405914 0.373127027172793 0.2718677439326628 +Rho protein signal transduction 9 26 2.050483194905352 0.0403173020491853 5.87378640776699 22.861650485436893 -0.1017182812857977 0.6596490805056876 3.4059616826242443 3.7588452567573647 0.7367263185096855 0.2876161119801693 1.0 0.3523884632837075 0.5815024054643041 0.1696171382308157 0.2580190497630057 +Regulation of actin filament based process 44 98 2.048917796744894 0.0404701537841694 24.810679611650485 88.33252427184466 -0.3530408434065963 0.5856849205784203 10.94904715117761 9.993134071926985 0.9428492227038882 0.3337866168599355 1.0 0.7355299784186087 0.7417994801140357 0.3322865168438173 0.0629249218875103 +Endoderm development 3 13 2.0475523369391664 0.0406038836656965 4.983009708737864 10.847087378640778 -0.7938944367052161 0.4190593002034311 2.4637572282019575 2.227022101140201 0.8266923030773482 0.3016739335867153 1.0 0.0230307909850112 0.0803264485176453 0.1129146346742184 0.2049440017843767 +Spliceosomal complex assembly 17 37 2.0466176161605727 0.0406956438209771 13.781553398058252 37.60436893203884 -0.5149748265952301 0.5804353739555388 6.496888688864706 2.4586444168979615 0.8001246828754943 0.328498888600479 1.0 1.0 0.3958350013250431 0.3568501183857085 0.0030132274761459 +Endoderm formation 1 8 2.0460289011034005 0.0407535272733272 3.400485436893204 6.631067961165049 -0.7004913341350544 0.4282812388420314 1.721452242324326 1.2636846360777478 0.8181211800490319 0.2926772113461608 1.0 0.0100088432903632 0.0368247433715485 0.1757094500446031 0.450369534817547 +Endodermal cell differentiation 1 8 2.0460289011034005 0.0407535272733272 3.400485436893204 6.631067961165049 -0.7004913341350544 0.4282812388420314 1.721452242324326 1.2636846360777478 0.8181211800490319 0.2926772113461608 1.0 0.0076498462283805 0.0285062952815799 0.1410845222447507 0.3817623273994432 +Protein demethylation 1 8 2.045171103045928 0.0408379923173254 2.5364077669902914 7.594660194174757 0.0519052155682225 0.5126282210134702 2.1511195343824596 1.782675700042577 0.9963977055315628 0.3122725477399503 1.0 1.0 0.2489059409173845 0.1582166891915067 0.4165733999734724 +Late endosome to vacuole transport 5 15 2.0416750631157843 0.0411837739563338 3.266990291262136 8.089805825242719 -0.1315479149485845 0.5330360381407673 2.1193921252303136 2.548403833425639 0.9470511834637332 0.3143422175801683 1.0 1.0 1.0 0.1162426898263886 0.0272826327042602 +Microtubule depolymerization 12 19 2.0400122264998872 0.0413491079857926 6.390776699029126 15.366504854368932 -0.3991532769953149 0.5270341386682836 3.376131579971715 2.275693517994133 0.955964518836966 0.3287812943349837 1.0 1.0 1.0 1.0 0.1288473164062758 +Regulation of small gtpase mediated signal transduction 19 45 2.036048650848224 0.0417454702161663 9.684466019417476 39.03155339805825 -0.0315938675658246 0.691071044005792 4.879862668797252 7.2054775897016246 0.7143360792430248 0.2962856488684606 1.0 0.6546458866969584 0.8813620189648567 0.9000227861571958 0.9029668317227711 +Morphogenesis of an epithelium 19 70 2.0349453112853424 0.041856376067213 17.774271844660195 61.37135922330097 -0.4349085455156319 0.5936167191923816 7.48266723406896 8.837005989108594 0.7443680387733929 0.30862826293263 1.0 0.4814692780400597 0.6289797590893236 0.8204547192811408 0.3354753663430884 +Negative regulation of rna splicing 6 17 2.029494908356223 0.0424079070691778 6.550970873786408 17.652912621359224 0.080708148531743 0.5352211753198439 3.085327637418694 1.454292695708865 1.0888581549716274 0.3350559056430555 1.0 1.0 0.0228441699597423 0.1162426898263886 0.3280048671308403 +Androgen receptor signaling pathway 3 16 2.0283149208456344 0.0425281170898241 5.293689320388349 14.941747572815531 -0.6773529272786829 0.4944295606449973 2.959050454588189 2.250459468592061 0.801077476955208 0.314128275511097 1.0 0.1583124314184509 0.2921659829416722 0.211484233041291 0.5144612633618493 +Response to steroid hormone 23 76 2.028164623267033 0.0425434491726552 13.225728155339803 70.58495145631068 0.1763568208377467 0.7136441197114008 5.741183042040811 6.972906426072971 0.6434426399957182 0.29607581376066 1.0 0.6220079992876584 0.5763422858730867 0.3491922662002177 0.0976997308890814 +Cellular response to heat 10 26 2.0274238574372108 0.0426190841269042 6.12621359223301 25.70145631067961 0.0436633535211099 0.737118339302819 5.1145701100570555 3.2873245555509327 0.618489874783639 0.275528391065193 1.0 0.2260688267312995 0.4017902994798545 0.0381586751774073 0.0397377338982377 +Regulation of microtubule nucleation 3 6 2.01253088744627 0.0441640040980835 2.599514563106796 5.747572815533981 -0.4963622603090221 0.5253130845280658 1.5128253504783864 1.0141565590436696 0.7977329243104433 0.2982880683009815 1.0 1.0 1.0 0.2199219252501269 0.010684483318579 +Establishment of spindle orientation 8 15 2.012026036837973 0.044217192424047 4.575242718446602 12.262135922330096 -0.4558232650703649 0.5591532870041406 2.3382984206885467 1.8615223180903369 0.7909913242751977 0.3139906935927975 1.0 1.0 0.0022569298755563 0.0276080433055301 0.0402069493791732 +Regulation of androgen receptor signaling pathway 0 11 2.0079950235995367 0.0446438204871875 3.9199029126213594 9.49514563106796 -0.7946965065020158 0.4397889660379592 2.113500751707282 1.50160940461703 0.744734692432943 0.2931175522061788 1.0 0.1114073342812727 0.2108642126213972 0.4492542995146525 0.6990268049674585 +Stress granule assembly 2 15 2.003015349949945 0.0451756409084538 6.0 15.864077669902912 0.1878667407984194 0.6213561303853748 3.795116944358793 1.6416812580981384 0.8599969043931267 0.3221919365712039 1.0 1.0 0.2186221342412543 0.1243944683174773 0.1199524552735497 +Glomerulus development 4 6 2.0022537214805616 0.0452574505449376 1.8567961165048543 4.453883495145631 -0.1573189447373245 0.5230844038756486 1.3151017632684965 1.4279829844582697 0.981592431903197 0.3154240515239371 1.0 1.0 1.0 0.548701439263177 0.2031992995383869 +Dna replication 43 123 1.9967129747208068 0.0458563718530331 31.58495145631068 114.497572815534 -0.3396652183206484 0.6367066368556744 13.744197954949136 11.241933199852268 0.7082885401335637 0.3115012314696074 1.0 0.7287712280963279 0.4764810936073842 0.6251752867700737 0.0540813230638557 +Ribonucleoside diphosphate biosynthetic process 3 8 1.994241975054564 0.0461256170023975 3.7402912621359223 7.305825242718447 -0.5605302856858331 0.4895470912057413 2.0236533128726246 0.928860377305359 0.7955353525185129 0.2993932103505706 1.0 0.0479914252810258 0.0938999510605359 0.2199219252501269 0.0823369674942117 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 14 31 1.9852058389187084 0.0471215749592239 7.216019417475728 27.59223300970874 -0.0519383977494633 0.6701209774741869 3.707043372113383 4.2275951832081935 0.7338177625451779 0.2919617735055492 1.0 1.0 0.7482734689396613 0.6670440396779332 0.6773868887078228 +Positive regulation of microtubule nucleation 3 5 1.984390242953444 0.0472123528887264 2.483009708737864 4.985436893203883 -0.549476929200216 0.5103235603289509 1.353600975859388 0.7000565534700517 0.7829850276740576 0.3012654429050781 1.0 1.0 1.0 0.1595576983806167 0.0034775277607499 +Smooth muscle cell differentiation 5 8 1.9805202656870904 0.0476450984642151 2.8567961165048543 6.463592233009709 -0.6649219242412014 0.4316004694406498 1.689883498938586 0.9858881505407028 0.8895810714012772 0.2989620349036794 1.0 1.0 1.0 0.6015494217836266 0.5446047019091178 +Negative regulation of supramolecular fiber organization 21 58 1.9782886517905456 0.0478961525934846 14.344660194174756 48.067961165048544 -0.1428490286443108 0.6549567366680907 6.317846938085449 4.776077392654747 0.8655851975479791 0.3242880376888204 1.0 0.4664619130311752 0.354745757728376 0.6063211801114292 0.1667469756624758 +Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 15 30 1.97804429773454 0.047923709565641 12.75485436893204 27.15776699029126 -1.0394074839648073 0.3838691113177802 4.648895967501926 1.866116590723231 0.9763640797952388 0.3319972339811646 1.0 1.0 0.299132167535026 0.0017240342445666 4.177932068990829e-05 +Defense response to gram positive bacterium 3 5 1.9772383381046252 0.0480146959423914 1.7427184466019416 4.492718446601942 0.047001436601032 0.591255631744899 1.20750902561483 0.9070625738948188 0.8367827300037257 0.3041101438807402 1.0 1.0 1.0 0.0105546488673461 0.0624183143373935 +Maturation of lsu rrna 5 25 1.971995175431171 0.0486101572779269 13.902912621359222 25.089805825242717 -1.3079065801307634 0.2925855633427192 5.026173365603582 0.9971770646271874 1.2736340990008843 0.3404565519165671 1.0 1.0 0.002509898486982 0.0303754901318735 0.010448798153629 +Nucleus organization 26 74 1.9692251423073523 0.0489272429281082 16.104368932038835 65.47330097087378 -0.103564924218844 0.6980407917164917 6.81455326872119 5.657005775700582 0.7144532625013605 0.3024914932591965 1.0 0.4420266901261166 0.1094639781610952 0.0006273361342856 0.0005914326993413 +Regulation of protein sumoylation 0 8 1.9679381185142657 0.0490751582148014 3.4854368932038833 7.402912621359223 -0.725601697541396 0.4320995009121844 1.685829447372771 0.9516420464638912 0.8218658298929149 0.296793205948647 1.0 0.0892490045576324 0.1709159600444602 0.3763073460681103 0.6133911232276724 +Apical junction assembly 11 21 1.967182530477495 0.0491621712731316 7.657766990291262 21.281553398058257 -0.3991796642921479 0.6015418780822775 4.183516296836986 3.063779871583071 0.7284421870478168 0.3006404141995876 1.0 1.0 1.0 0.2753302510648254 0.0520328360234653 +Protein localization to nucleoplasm 1 12 1.9667166329054424 0.0492158882531152 6.589805825242719 11.842233009708735 -0.7111130257075017 0.4506819138468095 3.073405018688247 0.9383226431242504 0.8434397724347313 0.3130165936381698 1.0 0.066549445548378 0.0080257871552124 0.0448845799435813 0.1467539296032722 +Rrna modification 6 16 1.9663537518577163 0.0492577617636418 7.111650485436893 14.118932038834952 -0.7982841010543059 0.4287832252169719 3.2556389011281026 2.761196241613708 0.9211584177527924 0.3226994558165146 1.0 1.0 0.2851312580635185 0.5706303062959026 0.229043322451679 +Protein refolding 8 12 1.9656461232238296 0.0493395023177971 3.6092233009708736 11.230582524271844 -0.1361358621145344 0.6481262090313329 2.583595067809296 0.9335892999889308 0.6822296736077167 0.2695633823034391 1.0 1.0 1.0 1.0 0.5935435236326052 +Protein localization to adherens junction 2 5 1.963945596513483 0.0495364013200207 2.6140776699029127 4.677184466019417 -0.4843133029871088 0.547158420612846 1.2994008603618568 0.4675528472819023 0.7357594030798231 0.2942514860679983 1.0 1.0 1.0 1.0 0.295251642909297 +Regulation of retinoic acid receptor signaling pathway 1 5 1.9619690483218817 0.0497660878926158 2.3276699029126213 4.186893203883495 -0.5895966217044587 0.5163021276169805 1.1770092953444231 0.3898257741936228 0.7556047037684771 0.2951985637153637 1.0 1.0 1.0 0.0284635326710383 0.0974859568290139 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..dce15b061093ff865c120476f491027bf70ecf86 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 6662, + "title": "Average number of proteins per term", + "value": 20.866256379465625 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0f03f231f412ee40c55d1dfa99fc4cf43e2b3b4d --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f4f891b85c1d8ce703121e6b66f04c5c4858df66 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,2223 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Rna processing 0.3996427318296955 8.356699426015593 6.449735677853646e-17 4.3634339085851467e-13 4.3634339085860994e-13 524 Q9GZR2,Q9Y3C6,Q9NWH9,Q8IXT5,O75150,Q14151,O95319,P38159,Q2NL82,Q9Y3B9,Q9HC36,Q15233,Q05048,Q7Z6E9,Q9P2D1,P52272,Q66PJ3,Q09666,Q9NZM5,Q6P6C2,Q14966,Q13523,P62841,P98175,Q96PU8,Q86V81,P08579,O43290,Q99590,O95104,P23246,Q96T37,Q08170,O14776,Q8IY81,P62424,Q9ULR0,Q9NPE3,Q99848,P78316,P62081,Q13769,Q9ULX3,Q9H9Y2,Q7L014,O43395,Q9UQ35,Q15007,Q01130,Q8N201,O75494,Q9Y2W2,Q96DF8,Q8NEF9,Q9H307,Q5QJE6,Q9BSC4,O60832,Q13573,P24928,Q9Y237,P98179,Q96E39,Q15637,Q8TDD1,Q9H2H8,Q9NR30,Q6UX04,P26599,Q9P013,O75400,O43709,Q9Y2W1,Q15050,Q9NTZ6,Q6PJT7,P82912,P61254,P16383,P19338,P08621,Q99459,Q76FK4,Q9BTD8,Q969X6,O43818,Q9NSI2,Q9H501,Q5JTH9,Q13310,P61353,Q9C0J8,Q92917,P05455,Q14498,P55081,P11940,P62263,O00566,Q02040,Q9BW85,P18615,Q15287,Q9H7Z3,Q14978,Q14692,Q05519,O94992,P11142,Q6UN15,Q15459,Q14331,P62913,P46087,Q9H7N4,P09012,P78332,P50914,Q13435,Q13243,Q96DE0,Q8IY67,Q9H6R4,P62314,Q9NW13,Q9BVJ6,P41223,Q14137,O95400,Q14690,Q9NY93,P62857,Q8N9T8,P39019,Q9Y383,Q86U38,Q15424,Q96PK6,Q12849,Q8WWH5,Q96SB4,P49756,Q9P2N5,P55769,Q9Y3I0,Q9BUQ8,O75691,Q53F19,O60942,P62847,Q5BKZ1,P84103,Q01081,Q9NQG5,Q8WVM0,Q96P16,Q9BXP5,Q9UKM9,P18583,Q9Y3B4,Q13123,Q9NV06,Q92945,Q8IY37,Q13427,Q9H9T3,Q8IX01,Q5T8P6,Q6P1J9,Q12972,Q9UNW9,Q2VPK5,Q99547,Q96GQ7,P62304,O15213,P62753,Q00839,O95232,Q9UKV3,Q96I25,Q96NC0,Q13151,Q9NW64,Q9NX58,Q9UJV9,P46777,Q9Y4C8,Q9H3H1,Q9H0H0,Q96FX7,O75475,Q9UHI6,Q92499,P51991,P33240,O60828 197 +Cell cycle 0.3282911939668354 5.843326646452117 5.116854310889952e-09 3.408790250727154e-05 1.136282780860362e-05 537 Q96ST3,Q9UPN4,P46013,Q12834,Q96GD0,Q8WYP5,O75150,P83731,Q96CS2,Q14676,Q13049,Q92974,Q9UN37,Q13564,P25205,Q9NZM5,O75528,O14974,Q9H981,Q9BSJ2,P43487,Q92878,P48681,Q9NQS7,P25490,P06748,P0DMV9,Q7L2J0,Q9Y6D9,P23246,P27816,Q14980,Q9UNZ2,Q9BRX5,Q13111,P54132,Q01082,Q13769,Q96CT7,Q15149,Q92733,Q8IXM3,Q13432,P51956,Q15007,Q01130,P53990,P55072,Q96EE3,Q15906,Q13464,Q15014,Q8WVB6,P04083,Q9UQN3,O60885,P51608,Q9HD42,Q5VUA4,Q9UIG0,P40818,Q7Z3K3,Q8IX12,P12270,O75147,O75400,O60934,Q9Y5K6,Q02241,Q14141,Q15050,Q96JM3,Q9BV73,Q16543,Q8TAE8,Q9NZZ3,P35658,Q8WW12,Q9H444,Q15910,P11274,P61254,Q99459,Q96EB6,Q99640,Q9H3R5,Q14807,Q9NYL9,Q9ULW0,Q9Y6G9,P35579,Q9Y496,Q9H7Z3,Q14978,P78536,O75116,O94992,P11142,P23258,Q9NRZ9,Q9Y3E7,Q9BRX2,Q9NPF5,Q9H0H5,Q9UHD8,O75179,Q7Z4H7,P46940,Q15648,Q9H7N4,P11802,Q13243,Q9Y448,Q9HAF1,Q96DE0,P16949,P09496,Q96QE3,O14745,P16104,O43491,P35580,Q15019,Q96PK6,O00311,P54652,Q08379,P21333,O95347,Q8NBT2,Q14683,Q9NQG5,Q8WWK9,Q16513,P18583,Q13123,Q9UNS1,Q15398,P39748,Q96QC0,Q13526,P15311,Q7Z7K6,Q14008,P62753,Q14203,Q01664,Q9UQE7,Q9UPT9,Q99496,Q86VI3,O95785,P02545,P33991,Q9Y6A5,P49916,P51610,Q9HC35,O96013,Q13112 160 +Chromatin remodeling 0.5116035238777429 4.56305704918015 5.041410849893069e-06 0.0330282168548078 0.0047979827259991 92 Q9UIF9,Q9NRZ9,Q96GM5,P84243,O60885,Q9NPF5,P11387,Q9H0U9,Q15059,Q9Y5B9,Q14839,Q86YP4,Q92922,Q12824,O95983,Q9UIG0,P62805,Q9UER7,Q9P2D1,Q96T23,Q16576,P16402,Q969G3,Q12830,Q8WXI9,Q9H981,Q7Z7K6,O14497,P25490,P06748,P16104,P10412,P16403,P07305,Q92925,P17096,Q13185,Q13111,Q99733,Q9HCK8,Q9NRL2,Q92522,Q6ZRS2,O94776,Q8WXX5,P26583,Q86U86,Q9UEE9,Q8N7H5,Q8TAQ2,P51610,Q5SSJ5,Q13112,Q68CP9,Q9P0M6,P25440,O75367,Q9H7B4,Q9NRF9,Q13330,Q15906 61 +Chromatin assembly or disassembly 0.4973184492183054 4.516249713909336 6.294443368748404e-06 0.0410666573885018 0.005241697715326 82 Q96ST3,Q9UIF9,Q9NRZ9,Q96GM5,P84243,Q9H0U9,Q9Y5B9,P51608,Q92922,Q8NEY8,Q12824,O95983,P62805,Q9UER7,Q96T23,P12270,Q66K74,P16402,Q969G3,Q7Z7K6,O14497,P06748,P16104,P10412,P16403,Q15910,P07305,Q13263,Q92925,P17096,P26358,Q96EB6,Q13185,Q13111,Q9NRL2,Q92522,O94776,Q8WXX5,P26583,Q8N7H5,Q8TAQ2,Q5SSJ5,Q13112,Q9H7Z3,Q9P0M6,P25440,O75367,Q9H7B4,Q9NRF9 49 +Actomyosin structure organization 0.5564059281610948 4.203531007385344 2.6278313462579916e-05 0.1606004167339697 0.0156900570603114 57 Q9Y281,Q13464,Q9NWH9,Q9Y2J2,Q9H0H5,Q7Z406,O00151,O60504,Q13136,Q9UN37,P49593,Q13177,O75147,Q07157,Q12802,Q92614,P16949,Q15942,Q9Y5S2,O43491,Q9Y6W5,Q9NYL9,Q16527,P35580,P35579,Q15149,P60903,P42345,Q14315,O75116 30 +Regulation of rna splicing 0.4783751828925027 4.161166859329215 3.166256291620151e-05 0.1901768055554036 0.0162258457036723 88 Q8IXT5,Q13573,P24928,P84103,O95319,P98179,P38159,Q96E39,Q15637,P18583,Q06787,P52756,P26599,Q13243,Q8IY67,Q09666,Q9Y2W1,Q9UNW9,P98175,Q96PU8,Q9NTZ6,Q00839,P09651,Q96T37,Q08170,P08621,P19338,Q9BTD8,Q9NW64,Q07666,Q14498,Q02040,Q12849,Q15007,Q15287,Q01130,Q96SB4,P49756,O75494,O60828,P11142,Q5BKZ1 42 +Regulation of mrna processing 0.4768073212499197 4.108835210960406 3.976596898414009e-05 0.232737392020549 0.0176613923581565 90 Q9NWH9,Q13573,O75150,O95319,Q14151,P38159,P98179,Q96E39,Q15637,P18583,Q06787,Q13247,P09012,Q7KZ85,P52756,P26599,Q8IY67,Q9Y2W1,Q6P1J9,Q9UNW9,P98175,Q96PU8,P22626,Q6PJT7,Q8IYB3,Q00839,P09651,Q96T37,Q08170,P08621,Q5VTR2,P19338,Q9BTD8,Q07666,Q14498,Q15424,Q8N684,Q8N7H5,Q15007,Q15287,Q01130,P18615,Q96SB4,Q16630,O75494,P49756,O00267,P11142,P84103 49 +Regulation of microtubule based process 0.4583665702096821 3.821445659973198 0.0001326716499225 0.5868386847492313 0.0414991755958216 77 P46821,Q13464,Q9UPN4,Q8WWK9,Q9NWH9,Q9UQN3,Q8TD16,Q9Y3E7,Q9Y3E1,P51608,Q9HD42,Q92974,O15344,P12270,P16949,Q9NZZ3,Q14008,P06748,P0DMV9,Q9H444,Q14203,Q9P270,Q14980,Q96EB6,Q9ULW0,Q9Y6A5,O60610,Q96PK6,Q16625,O75116 30 +Protein dna complex subunit organization 0.4475615788588427 3.799499709056867 0.0001449884824922 0.6193912370263301 0.0414991755958216 83 Q9UIF9,Q9NRZ9,Q96GM5,P84243,Q9NPF5,Q9H0U9,Q9Y5B9,Q92922,Q12824,O15160,Q15398,P62805,Q9UER7,Q7Z3K3,Q96T23,P16402,P17480,P29083,Q969G3,Q12830,Q9H981,Q7Z7K6,O14497,P25490,P06748,P16104,P10412,P16403,P07305,Q92925,P17096,Q9H3R5,Q13111,Q9NRL2,Q92522,Q6ZRS2,Q8WXX5,P26583,Q8N7H5,Q8TAQ2,Q5SSJ5,Q13112,Q9P0M6,P25440,O75367,Q9H7B4,Q9NRF9,Q15906 48 +Ribosomal large subunit biogenesis 0.509824487357089 3.791895735154831 0.0001495016833232 0.6306662868947195 0.0414991755958216 61 P62913,P46087,P83731,Q9Y3C1,Q9Y3B9,P50914,Q9NZM5,O75683,Q02878,Q9NVU7,Q9UHA3,P06748,P61254,Q8IY81,P62424,P62750,Q99848,P46777,Q9H9Y2,P55769,Q969S3 21 +Spindle organization 0.4443628127469369 3.641380966931646 0.0002711795019192 0.8358283647856745 0.0541440659518589 90 Q9UQN3,Q12834,Q9Y3E7,Q9H0H5,P51608,Q7Z4H7,Q96CS2,Q9HD42,Q15398,Q13561,Q9Y448,P12270,Q9BV86,Q02241,P16949,P15311,Q15555,Q9BSJ2,Q9NZZ3,Q14008,Q9NQS7,Q00839,P0DMV9,Q9H444,Q96CW5,Q14203,Q9UQE7,P27816,Q14980,Q9H3R5,Q9ULW0,Q9Y6A5,P35579,Q8WXW3,P55072,Q08379,P21333,P23258,Q14683 39 +Nucleosome assembly 0.5897206014164889 3.637047922354297 0.0002757806370852 0.8407856688631878 0.0541440659518589 35 P62805,Q9UER7,Q96T23,P16402,P06748,P16104,P16403,P07305,P10412,Q13111,Q92522,Q8WXX5,P26583,Q5SSJ5,Q9NRF9,Q9P0M6,P25440,Q9H7B4,Q13112 19 +Mitotic cytokinesis 0.5686632695181423 3.624023593865846 0.000290055128165 0.8552326867381201 0.0541440659518589 39 Q13464,Q9H444,Q8WWK9,Q13432,Q9UQN3,Q9Y3E7,Q01082,Q9H0H5,Q02241,P18583,P16949,Q14141,Q9NQS7,P35580,Q9HD42,Q9NZZ3,Q9UN37,P40818 18 +Dna packaging 0.4425999768021116 3.615484521518832 0.0002997863878702 0.8643227450666827 0.0541440659518589 90 Q96ST3,Q9UIF9,Q9NRZ9,Q9H0U9,P51608,Q8NEY8,Q9HD42,O95983,Q9UIG0,P62805,Q9UER7,Q96T23,P12270,P16402,Q9NTJ3,Q7Z7K6,P06748,P16104,P10412,P16403,Q15910,P07305,Q9UKV3,P26358,Q96EB6,Q13185,Q13111,Q9NRL2,Q92522,Q8WXX5,P26583,Q8N7H5,Q96SB4,Q5SSJ5,Q13112,Q9H7Z3,Q9P0M6,P25440,O75367,Q9H7B4,O95347,Q9NRF9 42 +Nucleosome organization 0.4923879204405506 3.6149154594707658 0.0003004456479265 0.8649175097224611 0.0541440659518589 62 Q96GM5,P84243,O60264,Q9NPF5,Q9Y5B9,Q9H0U9,Q92922,Q12824,P62805,Q9UER7,Q96T23,P16402,Q969G3,Q12830,Q9H981,O14497,P25490,P06748,P16104,P16403,P07305,P10412,Q92925,P17096,Q13111,Q99733,Q9NRL2,Q92522,Q6ZRS2,Q8WXX5,P26583,Q8N7H5,Q8TAQ2,Q5SSJ5,Q13112,Q68CP9,Q9P0M6,P25440,O75367,Q9H7B4,Q9NRF9,Q15906 42 +Microtubule cytoskeleton organization involved in mitosis 0.4348489004033558 3.603111487693229 0.0003144305828963 0.8769378709514668 0.0541995771110659 79 Q9UQN3,Q12834,Q9Y3E7,Q9H0H5,P51608,Q9HD42,Q15398,P12270,Q02241,P16949,Q9NZZ3,Q14008,P0DMV9,Q9H444,Q14203,Q9UQE7,P27816,Q14980,Q9UNZ2,Q9H3R5,Q9ULW0,Q9Y6A5,P55072,Q08379,P21333,Q14683 26 +Regulation of microtubule cytoskeleton organization 0.4917837663096252 3.548723429216265 0.0003871034329401 0.924179179429806 0.0587793656702014 60 P46821,Q13464,Q8WWK9,Q9UQN3,Q9Y3E7,Q9NWH9,Q9Y3E1,Q8TD16,P51608,Q9HD42,O15344,Q92974,P12270,P16949,Q9NZZ3,Q14008,P0DMV9,Q14203,Q9H444,Q9P270,Q14980,Q9ULW0,Q9Y6A5,Q16625 24 +Regulation of mrna splicing via spliceosome 0.4701353217569464 3.473151989951938 0.0005143839689725 0.9675387320529456 0.0716800928757759 66 Q13573,P18583,O95319,P98179,Q96E39,P38159,Q15637,P84103,P52756,P26599,Q8IY67,Q9Y2W1,Q9UNW9,P98175,Q96PU8,Q00839,Q96T37,Q08170,P08621,P19338,Q9BTD8,Q07666,Q14498,Q15007,Q15287,Q01130,P49756,Q96SB4,O75494,P11142,Q06787 31 +Negative regulation of transcription by rna polymerase ii 0.4818376854830251 3.4685789088162604 0.0005232188466046 0.9693951309087372 0.0716800928757759 150 Q96ST3,P45973,Q9NPF5,Q13573,P51608,Q9HCD5,O95747,Q86YP4,Q92785,Q15648,Q9UNS1,Q92541,P51858,Q9NP66,O95983,P12270,Q71SY5,O75446,P16402,Q8N6R0,Q9NZM5,Q04721,Q12830,Q9BQ70,Q8WXI9,P25685,P15311,P98175,P35251,Q6P1N0,P25490,O95104,P16403,P10412,P23246,Q7L2J0,Q15910,O14776,P26358,Q99496,Q9H1B7,Q96EB6,Q96EY1,Q13185,Q9HCK8,Q96L73,O94776,P62263,P26583,Q13416,P09874,P82979,P18615,P51610,Q9UHI6,P14373,Q9P0M6,O94992,Q15906 59 +Positive regulation of cell cycle process 0.4220679472764426 3.4410503805746337 0.0005794606288473 0.978963276005113 0.077207334187627 82 Q96ST3,P04083,Q16513,O60885,Q9H0H5,P51608,O75179,Q15648,Q15398,P11802,P39748,Q96QC0,P12270,Q02241,P43487,Q7Z7K6,Q96QE3,P06748,P23246,Q7L2J0,Q9Y6D9,Q15910,Q14980,Q9UNZ2,O95785,Q9NYL9,Q9Y6G9,Q13769,O00311,P54652,P78536,O75116 32 +Protein dna complex assembly 0.4900719107197084 3.428855228834643 0.0006061327516988 0.9823898649168338 0.079177576310152 56 Q9NRZ9,Q15398,P62805,Q9UER7,Q96T23,Q7Z3K3,P16402,P17480,Q7Z7K6,P06748,P16104,P16403,P07305,P10412,Q9H3R5,Q13111,Q9NRL2,Q92522,Q8WXX5,P26583,Q5SSJ5,Q13112,Q9P0M6,P25440,Q9H7B4,Q9NRF9 26 +Mrna transport 0.4224577620900651 3.4215591318270815 0.0006226318406594 0.9842239953894611 0.0797687177398731 79 O75152,Q9UKX7,Q9Y6M1,Q8WYP5,Q8TD16,P49790,Q92945,Q9NZI8,P12270,Q6P6C2,P55735,Q96PU8,Q86V81,P35658,Q9HAU5,Q9NPA8,Q9BY77,Q13769,O00159,Q8NFH5,P82979,Q9BZI7,P51991,Q53F19 24 +Mitotic spindle organization 0.4527724360062763 3.4020940765041625 0.0006687161409748 0.9883968324838154 0.079874090832181 70 Q9UQN3,Q12834,Q9Y3E7,Q9H0H5,P51608,Q15398,Q9HD42,P12270,Q02241,P16949,Q9NZZ3,Q14008,P0DMV9,Q14203,Q9H444,Q9UQE7,P27816,Q14980,Q9H3R5,Q9ULW0,Q9Y6A5,P55072,Q08379,P21333,Q14683 25 +Protein localization to cytoskeleton 0.6244129770909834 3.379142934174057 0.0007271219333215 0.9921390537728952 0.079874090832181 25 Q8IVD9,Q13561,Q9UPN4,Q86VS8,Q8WXW3,Q14980,Q9UNZ2,O60610,Q96JM3,Q9BV73,Q15555,Q15154,O15344,Q00839 14 +Recombinational repair 0.4662676845069297 3.3563494681148485 0.0007897870201878 0.9948235717080788 0.079874090832181 64 Q15014,Q9NPF5,Q9UNS1,P18887,P39748,Q7Z3K3,Q9HAF1,P25205,O60934,Q7Z4V5,P61088,P25490,P16104,P23246,P33991,P54132,P09874,O00311,P49916,Q9H1E3,Q15906 21 +Actin filament bundle organization 0.4927841596764875 3.350818523141694 0.0008057308651856 0.9953456019015816 0.079874090832181 50 Q13464,Q9NWH9,Q96GD0,Q05682,P35611,O00151,O60504,Q13136,P49593,Q13177,Q07157,P16949,P15311,Q15942,O43795,Q96IZ0,Q9UHB6,Q9Y6W5,P29966,P60903,P42345,Q9UQB8,O75116,P21333 24 +Cytokinesis 0.4420265506011299 3.299729419320308 0.0009677808888115 0.9984202333136042 0.079874090832181 71 Q13464,Q8WWK9,Q9UQN3,Q96GD0,Q9Y3E7,Q8WYP5,Q9H0H5,Q16513,P18583,Q9HD42,Q9UN37,P40818,O75400,Q13526,Q02241,P16949,Q14141,Q7Z7K6,Q9NZZ3,Q9NQS7,Q9H444,P35580,Q01082,Q15019,P35579,Q15149,Q13432,P53990,O75116 29 +Cytoskeleton dependent cytokinesis 0.4863423549659492 3.2930693891822083 0.0009910001383077 0.9986468450282364 0.079874090832181 51 Q13464,Q8WWK9,Q9UQN3,Q9Y3E7,Q9H0H5,P18583,Q9HD42,Q9UN37,P40818,Q02241,P16949,Q14141,Q9NZZ3,Q9NQS7,Q9H444,Q01082,P35580,Q15019,Q15149,Q13432,P53990,O75116 22 +Microtubule organizing center organization 0.4817429646986397 3.240782359191971 0.0011920215455842 0.99964591882755 0.079874090832181 51 Q9UPN4,Q9UQN3,Q9Y3E7,Q96CS2,Q9HD42,O14974,Q9BV73,P43487,Q9NZZ3,Q14008,Q8IWJ2,P06748,Q14203,Q9H444,Q9UNZ2,Q96EB6,Q96PK6,Q9Y496,O75116,Q08379 20 +Cytoskeleton organization 0.4182060126510347 3.20412046263199 0.0013547577989416 0.999880418881015 0.079874090832181 378 Q3KQU3,Q9UPN4,Q9NWH9,Q12834,Q8TD16,Q96GD0,Q05682,Q7Z406,Q96CS2,Q13049,Q92974,Q9UN37,Q9UNF0,Q12802,Q07157,O14974,Q15942,Q9NVU7,Q9BSJ2,P43487,P48681,Q9NQS7,O94832,P06748,P0DMV9,Q9P270,P27816,Q14980,Q9UNZ2,Q9UHB6,Q01082,Q15149,Q9NR12,Q16625,P14373,O43237,Q14315,P55072,Q5M775,O00159,Q5VZL5,Q9UQB8,Q96ED9,Q9Y281,Q13464,P04083,Q8IZP0,Q9UQN3,A1A4S6,P51608,Q96N67,Q9HD42,Q96HC4,O75147,P12270,O75400,Q9Y5K6,Q02241,Q04721,Q9BV73,Q86VS8,Q9NZZ3,Q8IWJ2,Q9Y5S2,Q9Y490,O43795,Q9H444,P84095,P11274,Q13308,Q96EB6,Q9H3R5,Q9NYL9,Q9ULW0,Q9Y6G9,P35579,O60610,Q96JJ3,Q9Y496,P47755,O75116,P23258,P46821,P07197,Q9Y3E7,Q9Y3E1,Q9Y2J2,Q9H0H5,Q5VSL9,Q9UHV9,P35611,Q7Z4H7,P46940,O15344,P46939,Q13177,Q9Y448,Q92614,Q4VCS5,Q9ULV4,P16949,O75592,Q15555,Q13813,O14745,O00165,O43491,Q9UM54,Q96IZ0,Q9Y6W5,O75369,Q8N8S7,P29966,P35580,Q16527,P04406,Q96PK6,P60903,Q8WXW3,O75190,Q9UKS6,Q9H2G2,Q86Y91,Q08379,P21333,Q14683,Q8WWK9,Q99661,Q9BVA1,P18583,P35221,O00151,O60504,Q15398,Q13136,P26038,P49593,Q13561,Q66K74,Q6WCQ1,Q13526,P49006,Q9BV86,O75146,P15311,Q9UJU6,Q14008,Q14247,P67936,Q00839,P59998,Q96CW5,Q14203,Q9UQE7,Q86VI3,O00291,P02545,P58107,Q9Y6A5,P42345,Q9HC35,O96013 162 +Rna splicing via transesterification reactions 0.4799797784560179 3.1796487531684696 0.0014745366622048 0.9999462202107366 0.079874090832181 187 Q9Y3C6,O95319,P38159,P52272,Q13523,P98175,Q96PU8,Q86V81,P08579,O43290,Q99590,P23246,Q96T37,Q08170,Q9ULR0,Q7L014,O43395,Q9UQ35,Q15007,Q01130,O75494,Q9Y2W2,Q96DF8,Q9H307,Q13573,P98179,Q96E39,Q15637,Q9H2H8,Q6UX04,P26599,Q9P013,O75400,Q9Y2W1,P08621,P16383,P19338,Q9BTD8,Q99459,Q92917,Q14498,P55081,P11940,O00566,Q9BW85,Q15287,P11142,Q15459,Q14331,P09012,P78332,Q13243,Q13435,Q8IY67,P62314,P41223,O95400,Q9Y383,Q96PK6,Q96SB4,P49756,P55769,Q9BUQ8,P84103,Q01081,Q9UKM9,P18583,Q9Y3B4,Q13123,Q92945,Q9UNW9,P62304,Q00839,O95232,Q96I25,Q96NC0,Q9NW64,Q9UJV9,Q9Y4C8,O75475,Q9UHI6,Q92499,P51991,O60828 84 +Protein depolymerization 0.4868867933782744 3.176582745750742 0.0014902127084772 0.9999515608257252 0.079874090832181 48 Q9Y281,P46821,Q8WWK9,Q99661,Q96GD0,Q9Y3E1,P35611,O15344,Q92974,Q9UN37,O00139,P35241,Q66K74,P16949,Q13813,Q14008,P48681,Q7Z460,Q99961,Q9UHB6,Q9NYL9,Q9ULW0,Q01082,Q86Y91,P47755,P11142 26 +Protein peptidyl prolyl isomerization 0.5564363524189131 3.124217912629841 0.0017827837189841 0.9999931242148145 0.079874090832181 29 Q8WUA2,Q13526,Q96AY3,Q9Y237,Q13356,P30414,Q00688,Q13427,Q6UX04 9 +Protein localization to microtubule organizing center 0.7015572756601651 3.1229268879435974 0.0017906222268893 0.9999934746653628 0.079874090832181 16 Q9BV73,Q14980,Q9UPN4,Q9UNZ2 4 +Ribosomal small subunit biogenesis 0.4584459868762979 3.119746064794142 0.0018100700847434 0.9999942689604776 0.079874090832181 59 Q9BSC4,Q9NV06,Q2NL82,P62841,Q15050,O75683,O15213,P62753,P06748,P82912,Q969X6,Q9Y2R9,P78316,P62081,Q9NSI2,Q8N9T8,P62857,P39019,Q9ULX3,Q86U38,P46782,P62263,P55769,Q96GA3,Q14692,O75691,Q8NEF9,P62847 28 +Regulation of dna recombination 0.469867979375693 3.104663611646147 0.0019049553852106 0.9999969577581552 0.079874090832181 51 P16403,P10412,Q15014,Q9HAF1,P07305,P16402,Q9NPF5,Q96QE3,Q7Z4V5,P20585,Q9UNS1,Q86V81,Q92522,Q92878,Q15906 15 +Regulation of spindle organization 0.6152495638751508 3.0894448281361195 0.0020053094760428 0.9999984430542384 0.079874090832181 23 P0DMV9,Q14203,P12270,Q9H444,Q9UQN3,Q9Y3E7,Q14980,Q9Y6A5,Q9HD42,Q9NZZ3 10 +Mrna metabolic process 0.4190123505388552 3.0724217809383383 0.0021232947228597 0.9999992917212815 0.079874090832181 371 Q9Y3C6,Q9NWH9,Q6PKG0,O75150,Q14151,O95319,P38159,Q9NZI8,Q15233,Q05048,Q7Z6E9,P52272,Q66PJ3,Q6P6C2,Q13523,Q8IZD4,P98175,Q96PU8,Q86V81,P08579,O43290,Q99590,O95104,P06748,P0DMV9,P23246,Q96T37,Q08170,O14776,Q9ULR0,Q9UKZ1,Q13769,Q7L014,O43395,Q9UQ35,Q15007,Q01130,O75494,Q9Y2W2,Q96DF8,Q9H307,Q8WWM7,Q13464,O60832,Q13573,P98179,Q96E39,Q15637,Q9H2H8,Q6UX04,P26599,Q9P013,O75175,O75400,Q9Y2W1,Q6PJT7,P08621,P16383,P19338,Q99459,Q9BTD8,Q13310,Q9C0J8,Q92917,P05455,Q14498,P55081,P11940,Q02040,Q9BW85,Q15287,P18615,Q9H7Z3,Q05519,O75116,O94992,P11142,Q6UN15,Q15459,Q9BRX2,Q14331,Q15648,Q9H7N4,P09012,P78332,Q13243,Q13435,Q96DE0,Q8IY67,P62314,Q9NW13,P41223,O95400,Q14690,Q6P2E9,Q9Y383,Q15424,Q96PK6,Q12849,Q8WWH5,Q96SB4,P49756,Q9P2N5,P55769,Q9BUQ8,Q8NC51,P52758,Q53F19,O60942,Q5BKZ1,P84103,Q01081,Q9NQG5,Q96P16,Q9BXP5,Q9UKM9,P18583,Q9Y3B4,Q13123,Q92945,Q8IX01,Q5T8P6,Q6P1J9,Q12972,Q9UNW9,P62304,Q00839,O95232,Q9UKV3,Q96I25,Q9HAU5,Q96NC0,Q13151,Q9NW64,Q9UJV9,Q9Y4C8,Q96FX7,O75475,Q9UHI6,Q9BZI7,Q92499,P51991,P33240,O60828 144 +Dna recombination 0.4255768714537332 3.0660391705219765 0.002169148956536 0.9999994785049714 0.079874090832181 110 Q15014,Q14249,Q9NPF5,O15347,P20585,P18887,Q9UNS1,P39748,Q15233,Q7Z3K3,Q9HAF1,P25205,P16402,O60934,Q7Z4V5,Q9H981,P61088,Q86V81,Q92878,Q96QE3,P25490,P16403,P16104,P10412,P23246,P07305,P33991,P54132,Q92522,P26583,P09874,O00311,P49916,Q9H1E3,Q15906 35 +Positive regulation of cell cycle 0.4089036573041511 3.0308961489337 0.0024382909655817 0.9999999135526548 0.0835321506345346 95 Q96ST3,P04083,Q16513,O60885,Q9H0H5,P51608,O75179,Q15648,Q13049,Q15398,P11802,P39748,Q96QC0,P12270,Q02241,P43487,Q7Z7K6,Q96QE3,P06748,P23246,Q7L2J0,Q9Y6D9,Q15910,Q9UPT9,Q14980,Q9UNZ2,O95785,Q9NYL9,Q9Y6G9,Q13769,O00311,P51610,P54652,P78536,O75116 35 +Microtubule polymerization or depolymerization 0.4760301028325512 3.0074788317093715 0.002634244702123 0.9999999766459052 0.0835682771692555 47 P46821,Q96SN8,Q8WWK9,Q99661,Q9NWH9,Q9Y3E1,P51608,Q92974,O15344,Q66K74,Q13526,P16949,Q15555,Q9BSJ2,Q14008,Q96CW5,P0DMV9,Q14203,Q7Z460,Q9P270,Q14980,Q9ULW0,Q16625,Q86Y91,Q08379,P23258 26 +Mrna processing 0.4698678762133057 2.992231680914947 0.0027694599964147 0.9999999905356926 0.0854173263709033 280 Q9Y3C6,Q9NWH9,O75150,O95319,Q14151,P38159,Q15233,Q05048,Q7Z6E9,P52272,Q66PJ3,Q6P6C2,Q13523,P98175,Q96PU8,Q86V81,P08579,O43290,Q99590,O95104,P23246,Q96T37,Q08170,O14776,Q9ULR0,Q13769,Q7L014,O43395,Q9UQ35,Q15007,Q01130,O75494,Q9Y2W2,Q96DF8,Q9H307,Q13573,P98179,Q96E39,Q15637,Q9H2H8,Q6UX04,P26599,Q9P013,O75400,Q9Y2W1,Q6PJT7,P08621,P16383,P19338,Q9BTD8,Q99459,Q9C0J8,Q92917,Q14498,P55081,P11940,Q02040,Q9BW85,Q15287,P18615,Q9H7Z3,Q05519,O94992,P11142,Q6UN15,Q15459,Q14331,Q9H7N4,P09012,P78332,Q13243,Q13435,Q8IY67,P62314,Q9NW13,P41223,Q14690,O95400,Q9Y383,Q15424,Q96PK6,Q12849,Q96SB4,Q9P2N5,P49756,P55769,Q9BUQ8,O60942,Q53F19,P84103,Q5BKZ1,Q01081,Q9NQG5,Q96P16,Q9BXP5,Q9UKM9,P18583,Q9Y3B4,Q13123,Q92945,Q8IX01,Q5T8P6,Q6P1J9,Q12972,Q9UNW9,P62304,Q00839,O95232,Q9UKV3,Q96I25,Q96NC0,Q13151,Q9NW64,Q9UJV9,Q9Y4C8,O75475,Q9UHI6,Q92499,P51991,P33240,O60828 121 +Metaphase plate congression 0.5114395219348415 2.951202927746376 0.003165388773517 0.9999999993283382 0.0914176092807475 36 Q13561,Q9H444,Q9Y6D9,Q99661,Q9UQN3,Q9Y3E7,Q8WXW3,Q14980,Q96EE3,Q15050,Q96JM3,Q9HC35,Q14807,Q9NQS7,Q9HD42,Q9NZZ3,Q9UN37,Q00839 18 +Establishment of cell polarity 0.4574805585749264 2.948251902528193 0.0031957654001038 0.9999999994517452 0.0914176092807475 50 P46821,Q13464,Q96SN8,P46108,Q96N67,Q96Q89,P26038,Q92614,Q4VCS5,P15311,P07900,O14745,P26367,Q14203,Q7Z460,P27816,Q13308,Q14980,Q9UNZ2,P08238,P35579,Q15334,P51956,O75116,Q13112 25 +Negative regulation of gene expression epigenetic 0.5266351342423082 2.947876183056545 0.0031996519065615 0.9999999994658028 0.0914176092807475 32 Q96ST3,Q9UIF9,Q9NRZ9,P12270,P07305,Q15910,P26358,P51608,Q96EB6,Q13185,Q9H7Z3,P14373,Q8NEY8,Q9P0M6,Q9NRF9,O75367,Q7Z7K6,O95983 18 +Rna splicing 0.4725045690131579 2.926514275300859 0.0034278377401069 0.999999999883774 0.0936867630988303 241 Q9Y3C6,Q8IXT5,O95319,P38159,Q15233,P52272,Q66PJ3,Q09666,Q14966,Q13523,P98175,Q96PU8,Q86V81,P08579,O43290,Q99590,P23246,Q96T37,Q08170,O14776,Q9ULR0,Q13769,Q7L014,O43395,Q9UQ35,Q15007,Q01130,O75494,Q9Y2W2,Q96DF8,Q9H307,Q13573,P24928,P98179,Q96E39,Q15637,Q9H2H8,Q6UX04,P26599,Q9P013,O75400,Q9Y2W1,Q9NTZ6,P08621,P16383,P19338,Q9BTD8,Q99459,Q92917,Q14498,P55081,P11940,Q02040,Q9BW85,Q15287,O00566,Q9H7Z3,Q05519,O94992,P11142,Q15459,Q14331,Q9H7N4,P09012,P78332,Q13243,Q13435,Q8IY67,P62314,Q9NW13,P41223,O95400,Q9Y383,Q96PK6,Q12849,Q96SB4,P49756,P55769,Q9Y3I0,Q9BUQ8,Q5BKZ1,P84103,Q01081,Q9UKM9,P18583,Q9Y3B4,Q13123,Q92945,Q13427,Q8IX01,Q12972,Q9UNW9,P62304,Q00839,O95232,Q9UKV3,Q96I25,Q96NC0,Q9NW64,Q9UJV9,Q9Y4C8,O75475,Q9UHI6,Q92499,P51991,O60828 106 +Establishment of rna localization 0.4006411993876345 2.872175146872907 0.0040765696151432 0.999999999998482 0.0963804455117389 97 O75152,Q9UKX7,Q9Y6M1,Q8WYP5,Q8TD16,P49790,Q92945,Q9NZI8,P12270,Q6P6C2,P55735,Q9H814,Q96PU8,Q86V81,P35658,Q14008,P06748,Q9HAU5,Q9NPA8,Q9BY77,Q13769,Q8NFH5,Q53F19,P82979,Q9H7Z3,Q9BZI7,P51991,O00159 28 +Poly a plus mrna export from nucleus 0.7643495731007751 2.871212410029342 0.0040890066220466 0.9999999999986032 0.0963804455117389 11 P82979,Q9NPA8,Q9BY77 3 +Regulation of alternative mrna splicing via spliceosome 0.517523724954252 2.863597868187227 0.0041885939649504 0.9999999999992824 0.0963804455117389 32 O95319,P38159,Q13247,P52756,P26599,Q8IY67,Q9Y2W1,Q9UNW9,P98175,Q00839,P09651,Q96T37,Q9Y580,Q07666,Q15007,Q15287,Q01130,P49756,Q06787,P17844 20 +Establishment or maintenance of cell polarity 0.3979756322224224 2.8544598918607256 0.0043110074787264 0.9999999999996836 0.0963804455117389 75 Q13464,Q92614,Q4VCS5,P15311,Q14008,Q9Y5S2,O14745,Q14203,P84095,P27816,Q13308,Q14980,Q9UNZ2,P02545,P35579,P51956,Q14168,Q5EBL8,Q8N3R9 19 +Negative regulation of dna recombination 0.6591043129921463 2.8502388104455507 0.0043686414497301 0.999999999999785 0.0963804455117389 16 P16403,P10412,P07305,P16402,P20585,P54132,Q92522 7 +Positive regulation of response to dna damage stimulus 0.471715171778017 2.831576794759735 0.0046319109354167 0.999999999999963 0.1001876319861886 44 P16104,Q7Z3K3,Q15014,Q9HAF1,Q14249,P09874,P61254,Q9NPF5,Q7Z4V5,Q9UNS1,P18887,P61088,Q9NYF8,Q96T60,Q15906 15 +Regulation of dna replication 0.4458454569441452 2.824325555451848 0.0047380232097307 0.9999999999999818 0.1019230246990512 51 Q8WVB6,Q14249,Q9ULV3,O75179,Q9UNS1,Q7Z6E9,Q9HAF1,O60934,Q9H981,Q96QE3,P25490,Q9UQE7,Q9BRX5,Q9UJZ1,O95785,Q9NRL2,P54132,O00311,P49916,Q9H1E3,Q9NRF9 21 +Multivesicular body organization 0.6251263994797017 2.821614980738285 0.0047782505220714 0.999999999999986 0.1023559645596148 19 Q9NP79,Q9H444,Q9UQN3,Q9Y3E7,O14964,P53990,Q9HD42,Q9UN37 8 +Non motile cilium assembly 0.6342921262375856 2.812243488451867 0.0049197245983116 0.9999999999999948 0.1028610124637491 18 Q9UPN4,Q14203,Q8WXW3,P27816,Q9UHD8,Q9Y366,Q9BV73,Q15555,P50570,Q8NCM8,O15078 11 +Muscle organ development 0.4928238843974249 2.809943118125959 0.004955025651171 0.9999999999999958 0.1028610124637491 37 Q9Y281,Q9P2D1,Q8NC56,O75446,Q14331,Q96EB6,Q7Z406,P80723,O75369,Q9Y5Q8,Q15648,P46939,Q15149,P50402 14 +Negative regulation of mrna metabolic process 0.4658746391109582 2.807865375365147 0.0049871070287887 0.9999999999999966 0.1028610124637491 45 Q6PKG0,A2RRP1,O75150,P38159,Q13247,Q9NZI8,P26599,Q9Y2W1,Q92804,P98175,Q6PJT7,Q00839,Q08170,Q5VTR2,Q9BTD8,Q13151,O60506,P11940,Q15287,P18615,O75494,O00267,Q06787 23 +Peptidyl lysine methylation 0.4750252781037575 2.793589416700547 0.0052126615660779 0.9999999999999992 0.1034117623082434 42 P16403,P10412,Q15910,P16402,O60885,P26358,Q13573,P51608,P18615,P51610,Q96EB6,P02545,Q9H7B4,Q92541,Q96L73 15 +Alternative mrna splicing via spliceosome 0.4741789138027837 2.7846384183868005 0.0053587443397928 0.9999999999999996 0.1043779367848346 42 O95319,P38159,P52756,P26599,P52272,Q8IY67,Q9Y2W1,Q9UNW9,P98175,Q00839,P23246,Q96T37,Q96I25,Q07666,Q15007,Q15287,Q01130,P49756,O60828,Q06787 20 +Chromosome localization 0.4739383180567966 2.7820926530079886 0.0054009618571724 0.9999999999999998 0.1045965345711706 42 Q99661,Q9UQN3,Q9Y3E7,Q15398,Q9HD42,Q9UN37,Q13561,Q15050,Q96JM3,Q9NZZ3,Q9NQS7,Q00839,Q9H444,Q9Y6D9,Q14980,P02545,Q14807,Q8WXW3,Q9HC35,Q96EE3 20 +Negative regulation of nucleobase containing compound metabolic process 0.449582781183248 2.777046584708158 0.0054855316221535 1.0 0.105463351410382 304 Q96ST3,Q9UPT8,Q6PKG0,O75150,P38159,P20585,Q96KM6,Q92541,Q9NZI8,Q9NP66,Q15233,Q9NZM5,Q9BQ70,Q12906,P25685,P98175,Q92878,Q9Y2K7,P25490,O95104,P23246,Q96T37,Q08170,O14776,Q7L2J0,Q9H1B7,Q96EY1,Q9HCK8,P54132,Q9NYF8,Q96L73,P82979,Q01130,O75494,P14373,Q15906,O60832,Q13573,P51608,Q9HCD5,Q99543,Q86YP4,Q15637,Q8TDD1,P18887,Q5VUA4,Q9UER7,P26599,Q8IX12,P12270,O75446,P16402,O60934,Q9Y2W1,Q04721,Q8WXI9,Q9H814,Q9NYB0,P53999,Q6PJT7,Q15910,P16383,P17096,P26358,Q9BTD8,Q96EB6,Q92522,O94776,P62263,P26583,P11940,Q15287,P18615,Q9NS86,Q9H7Z3,O94992,P11142,P45973,Q9NPF5,Q92785,Q15648,P51858,O95983,Q96DE0,Q71SY5,Q8N6R0,Q969G3,Q12830,Q9GZT3,Q6IAN0,P16403,P10412,P07305,Q8WXF1,Q13185,O75190,P21333,O95747,Q9UNS1,Q96T23,Q8WUB8,P15311,P80723,Q6P1N0,Q01664,Q99496,Q13151,Q13416,P09874,P51610,Q9UHI6,Q9P0M6 112 +Dna strand elongation 0.5860573372680037 2.7736061869149076 0.0055438744281293 1.0 0.105463351410382 22 P25205,O60934,P49916,Q9H1E3,Q9H981,P33991,Q92878,Q9NRF9 8 +Microtubule polymerization 0.4967046308086619 2.76909656379159 0.0056211972345256 1.0 0.105463351410382 35 P0DMV9,Q14203,Q9NWH9,Q9Y3E1,Q9P270,Q13526,P51608,Q14980,P16949,Q16625,Q9BSJ2,Q9ULW0,Q08379,Q14008,P23258 15 +Positive regulation of cytoskeleton organization 0.4293405537155522 2.699342997277931 0.0069476529225618 1.0 0.1183766336831379 56 Q9Y281,P46821,Q96SN8,Q9NWH9,Q96GD0,P51608,Q9UHV9,O60504,P49593,Q14008,P48681,Q14247,O00165,P0DMV9,Q14203,Q7Z460,Q9P270,Q14980,Q9Y6W5,P60903,P42345,Q16625,Q9UQB8,P14373,O75116 25 +Chromatin disassembly 0.6433976905594834 2.693809029866103 0.0070640626176685 1.0 0.1200530233645612 15 Q96GM5,Q66K74,Q92925,Q8TAQ2,Q9Y5B9,Q969G3,P17096,Q92922,Q12824,O14497 10 +Actin filament organization 0.4089911397864854 2.6876018910840127 0.0071967142057114 1.0 0.1210565069841499 119 Q9Y281,Q13464,Q8IZP0,Q9NWH9,Q96GD0,Q05682,P35611,P35221,O00151,O60504,Q92974,Q13136,P49593,Q13177,Q07157,Q6WCQ1,Q9Y5K6,Q9ULV4,P16949,P49006,O75146,Q15942,Q9UJU6,P15311,Q13813,P67936,O94832,O43795,O00165,P59998,Q14247,P84095,Q9UM54,Q96IZ0,O00291,Q9UHB6,Q9Y6W5,Q8N8S7,Q9NYL9,P29966,Q01082,O00159,Q15149,O60610,P60903,P42345,Q96JJ3,P14373,O75116,P47755,Q9UQB8,P21333 52 +Positive regulation of double strand break repair 0.5737225063183184 2.6791170737312053 0.0073816579774006 1.0 0.1214669070761152 22 Q15014,Q9HAF1,P09874,Q9NPF5,Q7Z4V5,Q9UNS1,P61088,Q96T60,Q15906 9 +Regulation of centrosome cycle 0.5950676976348933 2.678997994946866 0.0073842836033963 1.0 0.1214669070761152 20 P06748,Q9UPN4,Q9H444,Q96PK6,Q9UQN3,Q9Y3E7,Q96EB6,Q9HD42,Q9NZZ3 9 +Mitotic recombination 0.7698475965224286 2.673883334123581 0.0074978530388407 1.0 0.1227289851222534 9 Q92878,P20585 2 +Heterochromatin organization 0.4970784710888671 2.6720318161892065 0.0075393499714913 1.0 0.1229976047626189 32 Q96ST3,Q9UIF9,Q9NRZ9,P12270,P07305,Q15910,P26358,P51608,Q5SSJ5,Q96EB6,Q13185,Q9H7Z3,Q9NRF9,Q8NEY8,O75367,Q7Z7K6,O95983 17 +Maintenance of blood brain barrier 0.764240186938772 2.6447774996414437 0.0081744648793424 1.0 0.1278363498267127 9 Q07157,Q9UDY2,P55011,P11047,P18206 5 +Muscle structure development 0.3932376280740918 2.6351556644319216 0.0084098705285013 1.0 0.1301643308156221 105 Q9Y281,Q15014,P51608,O60271,Q14331,Q7Z406,O75179,Q15648,Q9H7N4,Q13049,Q96HC4,P46939,P26599,Q9P2D1,Q12802,O75147,O75446,P19022,Q7Z4V5,Q96PU8,P80723,P25490,Q15910,P26358,Q9H4M9,Q96EB6,P02545,O75369,P35579,Q15149,Q9NR12,P42345,Q14315,Q9H7B4,Q9Y5Q8 35 +Spindle assembly 0.421248300000778 2.634948038516634 0.0084150164142124 1.0 0.1301643308156221 58 Q9UQN3,Q12834,Q9Y3E7,Q9H0H5,Q7Z4H7,Q96CS2,Q9HD42,P12270,Q02241,Q15555,Q9BSJ2,Q9NZZ3,Q9NQS7,Q00839,Q96CW5,P0DMV9,Q9H444,Q9UQE7,Q14980,Q9ULW0,Q8WXW3,Q08379,P21333,Q14683 24 +Regulation of spindle assembly 0.6235584644588721 2.6156102742212624 0.0089068155082236 1.0 0.1367216703128716 16 P0DMV9,Q9H444,P12270,Q9UQN3,Q9Y3E7,Q14980,Q9HD42 7 +Regulation of neuron differentiation 0.5300442788685691 2.612571318425649 0.0089863940748802 1.0 0.137310452584523 25 Q96ST3,Q8WUJ1,Q13464,O60271,Q15648,Q13049,Q9NP66 7 +Viral transcription 0.5855027000839466 2.608820721717467 0.0090854827769979 1.0 0.1381199652180707 20 Q96T23,Q01664,O60858,Q13573,P17980,Q9H1E3,P14373,Q13049 8 +Negative regulation of dna metabolic process 0.461190221681709 2.584442109611368 0.0097536676964091 1.0 0.1424976627049954 40 P16403,P10412,P07305,P09874,P16402,O60934,Q92878,Q99543,P20585,P18887,P54132,Q92522,P53999 13 +Regulation of gene expression epigenetic 0.4420444035480735 2.5832648535525053 0.0097870158098989 1.0 0.142671989771437 46 Q96ST3,Q9UIF9,Q9NRZ9,Q96GM5,P84243,P51608,Q8NEY8,O95983,P12270,Q7Z7K6,O14497,Q00839,P07305,Q15910,Q96T37,P26358,Q96EB6,Q13185,Q9H7Z3,P14373,Q9P0M6,O75367,Q9NRF9 23 +Chromosome organization 0.3884517430543904 2.572214270353007 0.010105032932949 1.0 0.1453989835838157 381 Q96ST3,P46013,Q12834,Q15059,O75150,P20585,Q9NP66,Q9UN37,Q9P2D1,P25205,Q9H981,Q92878,Q9Y2K7,P25490,P06748,P23246,Q9Y6D9,Q96T37,Q9NPE3,Q14980,Q9NPA8,Q9BRX5,Q13111,Q9HCK8,P54132,Q96L73,Q8WXX5,Q9UEE9,Q5SSJ5,P05204,P14373,Q9NRF9,Q96EE3,Q15906,Q8WVB6,P04083,Q9UQN3,O60885,O60832,P11387,P51608,P13984,Q99543,Q86YP4,Q92922,P18887,Q9HD42,Q9UIG0,P62805,Q9UER7,Q7Z3K3,P12270,Q16576,P16402,O60934,O43709,Q02241,Q8WXI9,Q96JM3,Q15050,Q9NYB0,Q9NZZ3,Q9H444,Q15910,P05114,P17096,P26358,P49750,Q96EB6,Q9H3R5,Q14807,Q9NRL2,Q7LBC6,Q92522,Q9Y6G9,O94776,P26583,Q15291,Q9H7Z3,Q9H7B4,P23258,P45973,Q13283,Q9NRZ9,Q9Y3E7,Q9NPF5,Q9H0H5,Q9Y448,Q9HAF1,Q12830,P16403,P16104,P10412,P07305,Q13185,Q6ZRS2,Q15424,P54652,O95347,Q14683,O15347,Q13123,Q15398,P39748,Q96T23,Q96QC0,Q7Z7K6,Q9UQE7,Q9UPT9,Q9UKV3,Q99496,P33991,Q9Y6A5,Q96T60,P09874,P51610,Q9HC35,Q9H1E3,Q92499,Q9P0M6,P25440,Q13112 122 +Chromatin organization 0.4390220489163554 2.563949414890268 0.0103488626056089 1.0 0.1482669304915418 180 Q96ST3,P45973,Q9NRZ9,P46013,O60885,Q9NPF5,P11387,P51608,Q15059,O75150,Q99543,Q86YP4,Q92922,O95983,Q9NP66,Q9UIG0,P62805,Q9UER7,Q9P2D1,Q96T23,P12270,Q16576,Q9HAF1,P16402,O43709,Q8IXM2,Q12830,Q8WXI9,Q9H981,Q7Z7K6,P25490,P06748,Q9Y2K7,P16104,P10412,Q96T37,P05114,Q15910,P16403,P17096,P26358,P07305,Q9NPA8,Q9UPT9,Q99496,Q96EB6,Q13185,Q13111,Q9HCK8,Q9NRL2,Q7LBC6,Q92522,Q6ZRS2,Q96L73,O94776,Q8WXX5,Q15424,P26583,Q9UEE9,Q15291,P51610,Q5SSJ5,Q13112,P05204,P14373,Q9H7Z3,Q9H1E3,Q9P0M6,P25440,Q9H7B4,Q9NRF9,Q15906 72 +Double strand break repair 0.3802321670404786 2.552036550787642 0.0107095283045974 1.0 0.1527770397542364 97 Q15014,Q9NPF5,P18887,Q9UNS1,P39748,Q7Z3K3,Q9HAF1,P25205,O60934,Q7Z4V5,Q9H981,P61088,Q92878,P25490,Q9Y2K7,P16104,P23246,P33991,P54132,Q96T60,P26583,P09874,O00311,P49916,Q9H1E3,Q92499,P55072,Q15906 28 +Response to estradiol 0.6055987607611807 2.5506144412534484 0.0107533213425521 1.0 0.1530739888548768 17 P46821,Q15910,Q14249,P04083,O75592,P09104,O94788 7 +Negative regulation of mrna processing 0.544960677928247 2.5410907217636716 0.0110507241378925 1.0 0.1549893141192423 23 P26599,Q08170,P18615,Q9BTD8,O75150,O75494,P38159,P98175,Q6PJT7 9 +Regulation of microtubule polymerization or depolymerization 0.4689055533965798 2.5312267275713114 0.0113664349323567 1.0 0.1577264101065032 36 P46821,P0DMV9,Q14203,Q8WWK9,Q9NWH9,Q9Y3E1,Q9P270,Q14980,P51608,Q16625,P16949,Q92974,Q9ULW0,O15344,Q14008 15 +Positive regulation of microtubule polymerization or depolymerization 0.5841528769765346 2.5291080072616334 0.0114352831103934 1.0 0.1577264101065032 19 P0DMV9,Q14203,Q9NWH9,Q9P270,Q14980,P51608,Q16625,Q14008 8 +Inclusion body assembly 0.713383514704842 2.5050119882051503 0.0122447243048151 1.0 0.1628318703932204 10 P25685,P0DMV9,P54652,O75190 4 +Mitotic metaphase plate congression 0.4764785880127267 2.504992851380652 0.012245386830832 1.0 0.1628318703932204 33 Q13561,Q9H444,Q9Y6D9,Q99661,Q9UQN3,Q9Y3E7,Q8WXW3,Q96EE3,Q15050,Q96JM3,Q9HC35,Q14807,Q9HD42,Q9NZZ3,Q9UN37,Q00839 16 +Negative regulation of protein containing complex disassembly 0.4813336400355722 2.494575231820194 0.0126107990541446 1.0 0.16735685916078 31 O95104,P46821,Q8WWK9,Q01082,Q9Y3E1,Q9UHB6,P35611,Q13813,Q9NYL9,Q9ULW0,Q92974,P47755 12 +Positive regulation of chromosome organization 0.4288918492821672 2.4741197386199425 0.0133564923188307 1.0 0.1739779490173817 47 Q96ST3,O60832,P49959,Q8NEY8,P39748,Q96QC0,P12270,O60934,Q9NTJ3,P22626,P27361,Q92878,P09651,P23246,Q13263,P26358,Q14980,P13010,Q96T60,P50991,Q04837,P78371,O75367,O95347 24 +Chromosome condensation 0.5011892526942813 2.470709374554356 0.0134845356311195 1.0 0.1739779490173817 26 P16403,P10412,P07305,P16402,Q9UKV3,Q92522,Q9HD42,O95347 8 +Dna dependent dna replication 0.3581798958538804 2.4699674592841716 0.0135125343250248 1.0 0.1739779490173817 81 Q8WVB6,Q14249,Q9ULV3,P54098,Q9UNS1,Q9NR30,P39748,P25205,O60934,Q86V81,P35251,Q96QE3,Q9NY93,P17096,Q9BRX5,Q9UJZ1,Q96EY1,O95785,Q9NRL2,P33991,P54132,Q96T60,Q04837,Q13416,O00311,P49916,Q9H1E3,Q9BUQ8,O75717,Q9NRF9 30 +Stress fiber assembly 0.475708720270289 2.468190947972641 0.0135797858734671 1.0 0.1739779490173817 32 Q13177,Q13464,P60903,Q07157,Q9NWH9,P42345,P16949,Q15942,Q9Y6W5,O00151,O60504,O75116,Q13136,P49593 14 +Rna export from nucleus 0.4115394606196589 2.4617721645072868 0.0138252459253562 1.0 0.174427703358286 55 P12270,O75152,P82979,Q6P6C2,Q9NPA8,Q9BY77,Q9H814,P49790,Q86V81,P35658 10 +Defense response to bacterium 0.5739834164688024 2.4551712634106293 0.0140817482350312 1.0 0.1749023288976804 19 P39019,P26583,P82094,Q04721,Q96JM3,O75179,P78536,Q7Z434,Q96EE3 9 +Protein containing complex localization 0.4269361090866407 2.45148759590659 0.0142267089796472 1.0 0.1749023288976804 47 P06748,Q9UPN4,P23246,Q96EE3,P62841,P15311,O00291,Q9Y366,Q96GA3,Q14168,Q9NVU7,Q8NCM8,Q86U38,P33176 14 +Regulation of protein depolymerization 0.4564562247396839 2.4423196337616035 0.0145932197006768 1.0 0.1777331437767991 37 Q9Y281,P46821,Q8WWK9,Q01082,Q9Y3E1,Q96GD0,Q9UHB6,P35611,Q13813,Q9NYL9,Q9ULW0,Q92974,P47755,P48681 14 +Response to wounding 0.3650486839470215 2.4410283754889295 0.0146455039647033 1.0 0.1780444295854991 89 P04083,Q9UQN3,Q9Y3E7,Q13572,P55011,P00374,P27144,Q96AY3,P10586,Q6SZW1,Q9HD42,P18206,Q04721,Q5JRA6,Q9UIJ7,Q9NZZ3,Q9Y490,Q9H444,P49257,Q13308,P11047,P58107,P35579,Q13310,Q15149,P42345,Q16625,P78536,P21333 29 +Mitotic spindle assembly 0.4466149101700782 2.4302214746191027 0.0150895989361747 1.0 0.1797369074420289 40 P0DMV9,Q9H444,P12270,Q9UQE7,Q9UQN3,Q12834,Q9Y3E7,Q08379,Q9H0H5,Q02241,Q9HD42,P21333,Q9NZZ3,Q14683 14 +Regulation of histone methylation 0.4683139404953674 2.4254598698589156 0.0152890059698538 1.0 0.1809153779239187 33 O60885,P26358,Q13573,P51608,P18615,P51610,Q96EB6,P02545,Q92541,Q96L73 10 +Regulation of double strand break repair via homologous recombination 0.4834004248088048 2.423651016474897 0.0153653632361474 1.0 0.1814833793585625 27 Q7Z3K3,Q15014,Q9HAF1,P09874,Q9NPF5,Q7Z4V5,Q9UNS1,Q15906 8 +Wound healing 0.3819191425066393 2.4230338968896588 0.0153914904439489 1.0 0.1814833793585625 70 P04083,Q9UQN3,Q9Y3E7,Q13572,P55011,P27144,Q96AY3,Q9HD42,P18206,Q04721,Q5JRA6,Q9UIJ7,Q9NZZ3,Q9Y490,Q9H444,P49257,Q13308,P58107,P35579,Q15149,P42345,Q16625,P78536,P21333 24 +Viral budding 0.6016583382826025 2.419266716767375 0.0155518324610346 1.0 0.1825665263379728 15 Q9NP79,Q9H444,Q9UQN3,Q9Y3E7,Q9HD42,Q9UN37 6 +Folic acid metabolic process 0.8478389469395684 2.417660423164831 0.0156206467108468 1.0 0.182890594705908 6 P00374 1 +Positive regulation of dna repair 0.4642733605149769 2.4164283396454818 0.0156736110645829 1.0 0.1831887665127225 34 P16104,Q7Z3K3,Q15014,Q9HAF1,P09874,Q9NPF5,Q7Z4V5,Q9UNS1,P18887,P61088,Q96T60,Q15906 12 +Histone deacetylation 0.4670039587150473 2.412649487587754 0.0158370415922035 1.0 0.1841297924734033 33 Q96ST3,Q15014,P23246,Q16576,Q96PK6,O75528,Q9UHR5,Q8WXI9,Q96EB6,Q86YP4,O94776 11 +Regulation of vascular permeability 0.7417782381437186 2.4069015538992415 0.0160885061220645 1.0 0.1864028309307726 8 Q07157,Q9UDY2,Q16625,Q15149,Q02952 5 +Regulation of actomyosin structure organization 0.4771121194284708 2.406220844810464 0.0161185174638345 1.0 0.1864263252501139 29 Q13177,Q13464,Q12802,Q07157,P60903,Q9NWH9,P42345,P16949,Q9Y6W5,O60504,O75116,Q13136,P49593 13 +Dna conformation change 0.4093353952147717 2.3963997180627628 0.0165570234238754 1.0 0.1892752871874589 144 Q96ST3,Q8WVB6,Q13283,P04083,P11387,P13984,P51608,O15347,Q9HD42,Q9UIG0,P62805,Q9UER7,Q9P2D1,Q96T23,P12270,P25205,P16402,O60934,Q7Z7K6,Q92878,P06748,P16104,P10412,P16403,Q15910,P07305,Q9UKV3,P17096,P26358,Q9BRX5,Q96EB6,Q13185,Q13111,Q9HCK8,P33991,P54132,Q92522,Q8WXX5,P26583,Q5SSJ5,Q13112,Q9H7Z3,Q92499,Q9P0M6,P25440,Q9H7B4,O95347,Q9NRF9 48 +Positive regulation of innate immune response 0.4710176066904775 2.396237821752127 0.0165643389057088 1.0 0.1892752871874589 31 Q96ST3,Q9BY67,Q96PK6,P26583,Q7Z434,Q8WXF1,P43243,P30511,Q15648,P39019,O60828,Q9NZI8,Q15233 13 +Nucleosome positioning 0.7169586431035059 2.3955744468749995 0.0165943439613243 1.0 0.1892752871874589 9 P16403,P10412,P07305,P16402,Q92522 5 +Mrna splice site selection 0.5657037949516354 2.394584564035555 0.0166392060242608 1.0 0.1892752871874589 19 O75475,O95232,Q9ULR0,O95319,O75494,Q15637,Q9Y383,Q15459 8 +Regulation of inclusion body assembly 0.7391206884710854 2.393236519846626 0.0167004714236358 1.0 0.1892752871874589 8 P25685,O75190,P54652 3 +Regulation of telomere maintenance 0.4456043045460735 2.3931200414928275 0.0167057743719942 1.0 0.1892752871874589 39 O60832,P49959,P18887,Q96QC0,O60934,P22626,P27361,Q9NYB0,Q92878,Q00839,P09651,P07910,P49750,P28482,P13010,Q96T60,P50991,Q01780,P09874,Q92900,P78371,P17987 22 +Maintenance of cell number 0.4699930848215223 2.3864266212949423 0.0170130021488652 1.0 0.1908091251106739 31 O75175,Q15910,Q9UQE7,Q9BRX2,Q9BXP5,Q8N7H5,Q6P1J9,Q15906,P19022,Q86VS8,Q92541,Q9NZI8,Q13503,Q14683 14 +Negative regulation of ubiquitin protein transferase activity 0.6181090912773883 2.378291840141214 0.0173930540801587 1.0 0.1925312252179061 14 P62081,P46777,P62913,Q12834 4 +Positive regulation of neuron differentiation 0.6898775114289974 2.374962895768804 0.0175507143454147 1.0 0.1925312252179061 10 Q96ST3,Q8WUJ1,O60271,Q13049 4 +Midbody abscission 0.6752796701459256 2.373785243355369 0.0176067877181145 1.0 0.1925312252179061 11 Q9H444,Q9UQN3,Q9Y3E7,Q9HD42,Q9UN37 5 +Mitotic sister chromatid segregation 0.3644838348163946 2.3654476728305975 0.0180082879393366 1.0 0.1931903611141072 93 Q9UQN3,Q12834,Q9Y3E7,Q99661,Q96EE3,Q9H0H5,Q13123,Q9HD42,Q15398,Q9UIG0,Q9UN37,Q7Z3K3,Q9Y448,P12270,Q13561,Q02241,Q9NTJ3,Q15050,Q96JM3,Q9NZZ3,Q00839,Q9H444,Q9Y6D9,Q9UQE7,Q14980,Q14807,Q53HL2,Q9Y6G9,Q9Y6A5,Q8WXW3,Q9HC35,Q86Y91,O75367,O95347,P23258,Q14683 36 +Peptidyl proline modification 0.4482357642268417 2.3576318116745356 0.0183919245389234 1.0 0.1963573738434425 37 P62942,Q9Y3C6,Q8WUA2,P49792,Q9BV86,Q13526,Q96AY3,Q9Y237,Q13356,Q32P28,P30414,Q9H2H8,P13674,Q13427,Q00688,Q6UX04 16 +Rna stabilization 0.4861727806504722 2.337476085349426 0.0194144430020541 1.0 0.2043270446756477 26 P11940,Q6PKG0,Q9Y2W1,Q13151,P98175,Q9H814,Q9NZI8 7 +Maturation of ssu rrna 0.4377990980015495 2.3360174680382357 0.0194903311495253 1.0 0.2047348819149329 40 Q9BSC4,Q9NV06,Q2NL82,Q15050,O15213,P82912,Q969X6,P78316,Q9NSI2,Q8N9T8,P62857,P39019,Q9ULX3,Q86U38,P62263,P55769,Q14692,O75691,Q8NEF9 19 +Protein containing complex organization 0.2450952479528153 2.3284315897161982 0.0198891978779991 1.0 0.2070341191612973 617 Q9UIF9,Q96SN8,P84243,Q9NWH9,Q96GD0,Q8WYP5,P10809,O00233,Q05655,O95319,P38159,Q8N183,P83731,P49790,Q9H9Q2,Q13049,Q92974,Q12824,P62993,O94906,Q9UN37,P52756,O00139,Q15758,P35241,P36776,P17480,Q9NZM5,O15027,P62841,Q9H981,Q9BSJ2,P48681,O15212,Q99590,O43290,O95104,P25490,P06748,P0DMV9,Q9ULR0,Q9UBW8,Q9P270,Q14980,Q9H4M9,P62750,Q9UHB6,O95721,Q13111,P54132,Q01082,Q14197,Q15149,Q7L2E3,Q8WXX5,O43395,Q16625,Q5SSJ5,P55196,O75494,P40429,P53990,P55072,Q9UQB8,Q9NXW2,Q9NRF9,Q96EE3,Q15906,Q9Y281,Q9UQN3,P51608,Q15637,Q92922,Q99627,Q9HD42,P62805,Q9UER7,Q7Z3K3,P12270,P16402,P29083,Q9Y5K6,Q15050,Q13043,Q7Z3B4,Q9BU61,Q9NZZ3,Q9Y490,O95169,Q9H444,P82912,P16383,P17096,P11047,Q9H3R5,Q9NRL2,Q9NYL9,Q9ULW0,Q92522,O60610,Q8NFH5,P46782,P62263,P26583,Q00059,Q9BW85,P67870,P47755,Q9H7B4,O94992,P11142,Q15459,P23258,P46821,Q9NRZ9,Q9Y3E7,Q9Y3E1,Q9NPF5,P62913,P46087,O75347,P35611,O15160,O15344,Q13243,Q71SY5,Q969G3,Q12830,P16949,P09496,P62314,Q13813,O14745,O00165,P16403,P16104,P10412,P07305,O95400,P51809,Q12846,Q14137,P62942,Q99961,Q15056,Q9UJZ1,Q08257,Q9Y2R9,P62857,P39019,P08238,Q9Y383,O75251,Q6ZRS2,Q5VU43,P47985,Q04837,P11166,Q9H223,Q96SB4,Q9H269,P55769,Q9BUQ8,Q86Y91,Q9UN86,Q5EBL8,Q08379,Q8WWK9,Q96GM5,Q99661,Q9H0U9,Q9Y5B9,Q9Y4W6,Q15398,P07814,P26038,P20042,P33176,Q9NP79,Q96T23,Q66K74,P41214,Q13526,Q6P1J9,O75146,Q9UJU6,Q02878,Q9UMX0,O95456,Q7Z7K6,P61011,Q14008,Q14247,P62304,P59998,P23588,O95232,Q14203,Q01664,Q96HJ9,Q96CW5,Q8IUX1,Q7Z460,Q8TB37,O00291,P30101,P46777,O75489,P09132,P31153,P32929,P34932,O75475,P09874,Q8N684,P42345,Q8N7H5,P51610,Q8TAQ2,Q9UHI6,Q4KMQ2,Q92499,Q9P0M6,Q14168,O15533,P25440,O75367,O94788,Q13112 229 +Sarcomere organization 0.7039809020547657 2.3259899341307726 0.0200190876763413 1.0 0.2080610953194786 9 Q9Y281,Q14315,Q12802,Q15149 4 +Endosome organization 0.4387069021151566 2.3200723744119833 0.0203369624855207 1.0 0.2094047049127345 39 O60493,Q9NP79,O43752,Q86VS8,Q9H444,Q9UQN3,Q9Y3E7,Q15075,O14964,P53990,Q9HD42,P61020,Q9NZZ3,Q9UN37,P40818,Q96ED9 16 +Protein dna complex disassembly 0.5865395281564635 2.3179053700413492 0.0204544645410849 1.0 0.2102895721801043 15 Q96GM5,Q92925,Q8TAQ2,Q9Y5B9,Q969G3,P17096,Q92922,Q12824,O14497 9 +Mitotic cytokinetic process 0.6289826814264778 2.310904520970361 0.0208381292949959 1.0 0.2114834658941295 13 Q9H444,Q9UQN3,Q9Y3E7,Q9HD42,Q9UN37 5 +Non lytic viral release 0.6775368988400107 2.305969749560118 0.0211123226867266 1.0 0.2126472822750594 10 Q9H444,Q9UQN3,Q9Y3E7,Q9HD42,Q9UN37 5 +Muscle cell differentiation 0.3664655115093768 2.3049389783330496 0.0211699912094607 1.0 0.2126472822750594 73 Q9Y281,Q15014,P51608,O60271,O75179,Q13049,Q96HC4,P26599,O75147,Q12802,P19022,Q7Z4V5,Q96PU8,P25490,Q15910,P26358,Q9H4M9,Q96EB6,P02545,P35579,Q15149,P42345,Q14315,Q9H7B4 24 +Centrosome duplication 0.505121905270794 2.3043173268881185 0.0212048370164359 1.0 0.2126472822750594 24 P06748,Q9UPN4,Q9H444,Q96PK6,Q9UQN3,Q9Y3E7,Q96EB6,Q9HD42,Q9NZZ3,Q14008 10 +Regulation of actin filament bundle assembly 0.4638506035571944 2.303449874366927 0.0212535443565378 1.0 0.2126472822750594 30 Q13177,Q13464,P60903,Q07157,Q9NWH9,P42345,P16949,Q9Y6W5,O60504,O75116,P21333,Q13136,P49593 13 +Negative regulation of rna catabolic process 0.4586805672339709 2.3031744320102003 0.0212690307778975 1.0 0.2126472822750594 32 O60506,P11940,Q6PKG0,Q9Y2W1,O60832,Q92804,Q13151,Q9GZT3,Q9H7Z3,P98175,Q9H814,Q9NZI8,Q06787,Q00839 14 +Cytoplasmic microtubule organization 0.5432779228782948 2.293199132800892 0.0218365430609384 1.0 0.2155185924029209 20 Q96CW5,Q14203,Q7Z460,Q9P270,Q14980,P15311,Q9H2G2,Q9BSJ2,Q86VS8,P23258,Q96ED9 11 +Meiotic cell cycle 0.394256817645391 2.28953640773886 0.0220482050467563 1.0 0.2172857130495422 58 P16104,Q12834,O60934,P35579,Q14980,P54652,O95347,Q08379,Q5VUA4,Q92878,Q9NQS7,Q14683 12 +Positive regulation of histone methylation 0.5029303229640102 2.2858389729598545 0.0222636807440919 1.0 0.2184398249147868 24 O60885,P26358,Q13573,P51608,P18615,P51610,Q96EB6,P02545,Q92541 9 +Regulation of mitotic spindle assembly 0.6021391234792404 2.275408636121584 0.0228814277913893 1.0 0.222210017414338 14 P0DMV9,Q9H444,P12270,Q9UQN3,Q9Y3E7,Q9HD42 6 +Cortical cytoskeleton organization 0.4790043269975259 2.273327508452064 0.0230064510152403 1.0 0.2225871179241899 26 Q13464,P84095,O43491,Q9Y2J2,Q9H0H5,Q5VSL9,P15311,Q9UN37,Q9Y490 9 +Positive regulation of nucleobase containing compound metabolic process 0.3192615273881189 2.2708817256134193 0.0231541388053833 1.0 0.2225871179241899 436 Q96ST3,Q9NWH9,O60858,O00233,P38159,Q13049,Q92974,Q9NZI8,O15078,Q9P2D1,P82094,P17480,O75528,O14974,Q12906,P52815,Q8IZD4,Q7Z4V5,Q9H981,Q86V81,P61088,Q92878,P25490,P06748,Q7L2J0,P23246,Q96T37,O14776,Q9NPA8,Q9H1B7,Q9BRX5,Q9HCK8,P54132,Q13769,Q96CT7,Q9NYF8,Q96I24,Q96L73,Q8IVW6,P17980,P14373,P55072,Q15906,Q13464,Q15014,Q8WVB6,Q14249,O60885,O60869,Q13573,P51608,O60832,P13984,P24928,P98179,Q96E39,Q99543,Q92922,P18887,Q5VUA4,Q9NR30,Q9UIG0,Q9UER7,Q7Z3K3,Q8IX12,O75175,O60934,O43709,Q9Y2W1,P53999,P05114,P84095,P08621,P17096,P19338,Q99459,Q96EB6,O94776,P17544,P11940,P26583,Q00059,P18615,Q14978,O75116,Q9H7B4,P11142,Q9NPF5,Q9ULV3,Q92785,Q15648,Q9H7N4,P51858,Q13243,Q9HAF1,Q71SY5,Q969G3,Q12830,Q9NVC6,Q9NXV6,P35251,Q96QE3,P35269,P41223,P16104,Q9Y467,Q9UM54,Q6ZRS2,Q96PK6,Q12849,Q9NQG5,Q8WWK9,O95747,Q9UNS1,Q92945,Q96T23,Q96QC0,Q8WUB8,Q13526,Q01664,Q9UPT9,Q7Z434,Q96T60,P09874,P42345,P51610,Q8NCF5,Q9H1E3,O60828 129 +Histone h2a acetylation 0.6570614884627559 2.268718462747797 0.0232854521183931 1.0 0.2235269193267079 11 Q9NPF5,Q15014,Q15906 3 +Positive regulation of response to biotic stimulus 0.4461621499576989 2.266873816595681 0.0233979351432154 1.0 0.2241753312893556 35 Q96ST3,Q9BY67,Q96PK6,P26583,Q7Z434,Q8WXF1,P43243,O75179,P30511,Q15648,P39019,O60828,Q9NZI8,Q15233 14 +Regulation of microtubule polymerization 0.4999950491752334 2.2610443401714213 0.0237565114912905 1.0 0.2244297650127051 24 P0DMV9,Q14203,Q9NWH9,Q9P270,Q14980,P51608,P16949,Q14008 8 +Positive regulation of histone modification 0.4227088445116376 2.25787760632183 0.0239532911112632 1.0 0.2244297650127051 43 O60885,P26358,Q13573,P51608,P18615,O75150,P51610,Q96EB6,P02545,Q9Y3Y2,P61088,Q92541 12 +Mitochondrion morphogenesis 0.6542369773738789 2.2523291442749427 0.0243014797265637 1.0 0.2259842954769097 11 Q8TB37,Q9GZT3,Q7Z406,Q15149,Q9GZY8 5 +Protein localization to cell cell junction 0.6891311100525144 2.2457471046018513 0.024720211136213 1.0 0.2287306202631267 9 Q07157,Q13112,Q9UDY2,P18206 4 +Tissue morphogenesis 0.3463767179413907 2.2442776232941126 0.024814544366758 1.0 0.2290517970655539 83 Q9NWH9,O95747,Q9UNS1,Q15648,O15078,P18206,Q9P2D1,Q04721,P15311,Q13043,O95487,O14745,Q96T37,Q13308,P62081,Q12849,P42345,Q9Y366,P78536,P25440,P21333,O94788,Q8N3R9 23 +Mrna export from nucleus 0.4292606540153457 2.244135473117347 0.0248236862025412 1.0 0.2290517970655539 40 P12270,O75152,P82979,Q6P6C2,Q9NPA8,Q9BY77,Q86V81 7 +Negative regulation of cytoskeleton organization 0.394815683237901 2.238361219463852 0.0251975088391391 1.0 0.2311975400634659 54 P46821,Q8WWK9,Q9NWH9,Q9Y3E1,P35611,O15344,Q92974,Q13136,Q13177,Q07157,P16949,O75146,Q13813,P06748,Q9UHB6,Q9NYL9,Q01082,Q9ULW0,Q96PK6,P47755 20 +Response to heat 0.4331191062349306 2.237430249402958 0.0252582333397914 1.0 0.2311975400634659 38 Q9UER7,P0DMV9,O75475,P12270,Q16576,P42345,O75190,P54652,P31689,Q99543,P25685,Q96EB6,Q96EY1,P55072 14 +Microtubule cytoskeleton organization 0.4226077548209523 2.2373349514087115 0.0252644564944766 1.0 0.2311975400634659 189 Q3KQU3,Q9UPN4,Q9NWH9,Q12834,Q8TD16,Q96CS2,Q92974,O14974,Q9BSJ2,P43487,Q9NQS7,P06748,P0DMV9,Q9P270,P27816,Q14980,Q9UNZ2,Q16625,O43237,P55072,Q96ED9,Q13464,Q9UQN3,P51608,Q96N67,Q9HD42,O75147,P12270,Q02241,Q9BV73,Q86VS8,Q9NZZ3,Q8IWJ2,Q9H444,Q96EB6,Q9H3R5,Q9ULW0,Q9Y6G9,P35579,Q9Y496,O75116,P23258,P46821,Q9Y3E7,Q9Y3E1,Q9H0H5,Q7Z4H7,O15344,Q9Y448,P16949,Q15555,P04406,Q96PK6,Q8WXW3,Q9H2G2,Q86Y91,Q08379,P21333,Q14683,Q8WWK9,Q99661,Q9BVA1,P18583,Q15398,Q13561,Q66K74,Q9BV86,Q13526,P15311,Q14008,Q00839,Q96CW5,Q14203,Q9UQE7,P02545,Q9Y6A5,Q9HC35 77 +Regulation of epithelial cell differentiation 0.525799588941169 2.228286347709068 0.0258614261494236 1.0 0.2334471394903192 21 Q13464,Q15910,Q14980,O14974,O95747,Q15648,P18206 7 +Positive regulation of double strand break repair via homologous recombination 0.5594208719001814 2.227721105888069 0.0258991186834407 1.0 0.2334471394903192 17 Q15014,Q9HAF1,Q9NPF5,Q7Z4V5,Q9UNS1,Q15906 6 +Regulation of ubiquitin protein ligase activity 0.5714789604287163 2.215937914581815 0.0266957544458574 1.0 0.2374460829349833 15 P62081,P46777,P62913,Q12834 4 +Protein sumoylation 0.592603893111691 2.21348812685842 0.0268640109117459 1.0 0.23812089573511 14 P49792,P14373,P61956,Q9UBT2,Q9NP66 5 +Peptidyl lysine modification 0.3722511441087583 2.213272675928493 0.0268788522354852 1.0 0.23812089573511 111 Q96ST3,Q15014,O60885,Q9NPF5,Q13573,P51608,Q96AY3,Q92541,O95983,Q9NP66,Q9HAF1,P16402,O75528,P61956,Q9BX68,P16403,P10412,Q15910,Q9UPT9,P26358,Q9NPA8,Q96EB6,P02545,Q6ZRS2,Q96L73,Q15291,P18615,P51610,P14373,Q9UBT2,Q9H7B4,Q9NRF9,Q15906 33 +Monocyte differentiation 0.7533119933479915 2.2110064845186357 0.0270353880182501 1.0 0.2390495777695689 7 P35579,Q15648,Q9UKV3 3 +Epithelial cell differentiation involved in kidney development 0.7520498450013513 2.204845973016908 0.0274649047719537 1.0 0.2417056744924118 7 O95747,P80723,Q04721,P11047 4 +Cell differentiation involved in kidney development 0.7520498450013513 2.204845973016908 0.0274649047719537 1.0 0.2417056744924118 7 O95747,P80723,Q04721,P11047 4 +Ribosome assembly 0.3938037468482817 2.2038045681208636 0.0275380911868305 1.0 0.2418892423536893 52 P06748,P46782,Q14137,P62263,P82912,Q9NZM5,P62750,P62913,P62841,P46087,Q15050,P83731,Q02878,P62857,P46777,P39019,Q7L2E3 17 +Positive regulation of protein polymerization 0.4510158097170112 2.2032609384973605 0.0275763624219678 1.0 0.2418892423536893 31 P0DMV9,Q14203,Q9NWH9,Q9P270,P42345,Q14980,P51608,Q16625,Q14008,Q14247 10 +Escrt complex disassembly 0.6812696490290728 2.203000833269486 0.0275946899112584 1.0 0.2418892423536893 9 Q9NP79,Q9UQN3,P53990,Q9HD42,Q9UN37 5 +Regulation of cytoskeleton organization 0.4039237206394809 2.1976961301217894 0.0279707675181786 1.0 0.2448636704416635 155 Q9Y281,P46821,Q13464,Q8WWK9,Q9NWH9,Q96GD0,Q8TD16,Q9UQN3,Q9Y3E7,P51608,Q9Y3E1,Q9UHV9,P35611,P46940,O60504,Q92974,Q9HD42,O15344,Q13136,P49593,Q13177,Q12802,Q07157,P12270,Q66K74,Q9Y5K6,Q04721,P16949,O75592,Q9UJU6,P15311,Q15555,O75146,Q13813,Q9NZZ3,P48681,Q14008,O00165,Q14247,P06748,Q00839,P0DMV9,Q9H444,P59998,P84095,Q14203,Q9P270,Q14980,Q86VI3,Q9UHB6,Q9Y6W5,Q9NYL9,Q01082,Q9ULW0,Q9Y6A5,O60610,Q96PK6,P60903,P42345,Q16625,P14373,O75116,P47755,Q9UQB8,P21333 65 +Intermediate filament organization 0.7498861248739225 2.1942759790058757 0.0282155752536883 1.0 0.2457152448889826 7 P07197,O75190,P58107 3 +Suppression of viral release by host 0.6997113440870366 2.1882642405054855 0.0286503600897021 1.0 0.2478203733285866 8 Q13049,O60858 2 +Protein localization to microtubule 0.678528158029357 2.1880512105824264 0.0286658722488613 1.0 0.2478203733285866 9 Q96JM3,Q15555,Q00839,O15344,O60610 5 +Negative regulation of mrna splicing via spliceosome 0.5608964483710992 2.187850382560036 0.02868050252722 1.0 0.2478203733285866 16 P26599,Q08170,Q9BTD8,O75494,P38159,P98175 6 +Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.5525136642745292 2.17857142872473 0.0293635205971947 1.0 0.2514392984813768 17 Q9H444,Q9UQN3,Q9Y3E7,Q9HD42,Q9UN37 5 +Humoral immune response 0.5870871536957947 2.1774976819036818 0.0294434545799007 1.0 0.2518001211955052 14 P39019,Q96JM3,Q04721,P05204 4 +Tissue regeneration 0.7459867656106669 2.1751987828882924 0.0296152233571644 1.0 0.2529443820582434 7 Q7Z4V5,Q15910,P58107 3 +Microtubule organizing center localization 0.5866259111952135 2.1744831547350554 0.0296688691367419 1.0 0.2530781129180215 14 Q8TD16,Q15398,P33176,P15311 4 +Ribosomal large subunit assembly 0.4997164532921445 2.1723258672716614 0.0298310922601667 1.0 0.2535560931662286 23 Q9NZM5,P62750,P62913,P46087,P83731,Q02878,P46777,Q7L2E3 8 +Intraciliary transport 0.6751529553871795 2.1696155882500054 0.030035979484388 1.0 0.2538322389874974 9 Q9UPN4,Q9Y366 2 +Regulation of response to reactive oxygen species 0.6392902094710138 2.1651587892829576 0.0303755270905419 1.0 0.2548636794423051 11 Q9NWH9 1 +Microtubule nucleation 0.5491285645510016 2.1544056710406947 0.0312083722341149 1.0 0.2605390674482131 17 Q96CW5,Q14203,P0DMV9,Q9P270,P51608,Q9BSJ2,Q9ULW0,Q08379,Q14008,P23258 10 +Blood vessel morphogenesis 0.3450899693656822 2.153464961314409 0.0312821549665769 1.0 0.260828180710057 87 Q13464,P04083,P55011,P51608,Q96AY3,Q05682,Q15648,Q9UII2,Q9P2D1,Q07157,Q4VCS5,Q04721,Q96JM3,Q13043,P19022,Q96PU8,Q5JRA6,O95487,Q96T37,P19338,Q96EB6,Q9UGM6,O14964,P35579,Q12904,O96013,P21333 27 +Regulation of telomere capping 0.6719658536416903 2.152176812922439 0.0313834311347642 1.0 0.2610192487138572 9 O60934,Q92878,P18887 3 +Negative regulation of intracellular transport 0.5153935136418643 2.1466275463200097 0.0318229450954246 1.0 0.2620574292036078 21 P12270,P49257,Q8NBM4,P49790,Q07960 5 +Striated muscle cell development 0.6022886744430548 2.144325398143275 0.0320068231429111 1.0 0.263246241701326 13 Q9Y281,Q12802,O75147,Q14315,Q9NYL9,Q15149 6 +Cytokinetic process 0.5148600917230339 2.1424266524543616 0.0321591650795931 1.0 0.2638924764252862 21 Q9H444,Q9UQN3,Q9Y3E7,Q9H0H5,Q9HD42,P35579,Q15149,Q9UN37 8 +Kidney epithelium development 0.5814935151147507 2.1408832570186016 0.0322834536605536 1.0 0.2638924764252862 14 P78540,Q04721,P11047,O95747,P80723,P46940 6 +Regulation of rna export from nucleus 0.6478290225228849 2.1378827239300464 0.0325262627385514 1.0 0.2649503267468515 10 P12270,P49790 2 +Extracellular matrix assembly 0.7852443954269899 2.1338505039759688 0.0328550202147246 1.0 0.2672529238955989 6 Q96AY3,P07942 2 +Rrna metabolic process 0.4144491152695267 2.120844979717343 0.0339348500805192 1.0 0.2746949832763293 186 Q9GZR2,Q8WVM0,Q9BRX2,Q9BSC4,O60832,Q14331,Q9Y237,P62913,P46087,Q8TDD1,Q2NL82,Q9NV06,O15160,Q9Y3B9,Q9HC36,Q9NR30,P50914,Q9P2D1,Q96DE0,Q8WUA4,O43709,Q9NZM5,P62841,Q15050,Q9H6R4,Q99547,Q96GQ7,Q9BVJ6,O43290,O15213,P62753,Q14137,Q14690,P82912,Q8IY81,P62424,Q9NPE3,P61254,P19338,Q9NY93,Q76FK4,Q969X6,Q99848,O43818,Q9BQ61,P78316,P62081,Q9NSI2,Q9H501,P62857,P46777,P39019,Q5JTH9,Q9ULX3,P61353,Q86U38,Q9H9Y2,P62263,Q13428,O00566,P42345,P55769,Q9Y2W2,Q14978,Q14692,Q9P0M6,Q8NEF9,Q9Y5Q8 68 +Histone methylation 0.3854280106361594 2.1196183333316863 0.0340382451148206 1.0 0.2751975594113293 54 P16403,P10412,Q15910,P16402,O60885,P26358,Q13573,P51608,Q15291,P18615,P51610,Q96EB6,P02545,Q9H7B4,Q92541,Q96L73 16 +Protein transport along microtubule 0.7805817009484134 2.112374872751954 0.0346543084587585 1.0 0.2783725140201779 6 Q9UPN4,P33176 2 +Ribonucleoprotein complex subunit organization 0.3790992789473368 2.1075276233666194 0.035071869849903 1.0 0.2791118682431379 127 O95319,P62913,P46087,Q15637,P83731,P33176,Q13243,Q9NZM5,P41214,P62841,Q15050,P62314,Q02878,O43290,Q99590,P23588,O95232,Q14137,O95400,Q9ULR0,P82912,P16383,P62750,Q15056,Q9Y2R9,P62857,P46777,P08238,P39019,Q9Y383,Q7L2E3,P46782,O75475,P62263,O43395,Q9BW85,Q9UHI6,O75494,P55769,Q9BUQ8,Q92499,P40429,P55072,O94992,Q15459 45 +Regulation of nucleobase containing compound transport 0.6293545188548486 2.106808034416081 0.0351342227845901 1.0 0.2791118682431379 11 P12270,P49790 2 +Endothelium development 0.4599009966412825 2.1007139822607375 0.0356660811781015 1.0 0.2818593508997776 26 Q13464,Q07157,Q9NWH9,Q9UDY2,O60869,P55196,P15311,O14974,P67870,O75116,P18206 11 +Spliceosomal tri snrnp complex assembly 0.6406034812813859 2.096581821137624 0.0360306099141198 1.0 0.2837304057303388 10 O95400,Q9UHI6,O43395 3 +Protein localization to membrane raft 0.841857149136168 2.09204317347344 0.0364346538041902 1.0 0.2860233646485371 5 Q9BRK0 1 +Positive regulation of dna dependent dna replication 0.680967652513223 2.089268313887329 0.0366835770090854 1.0 0.2868380164724496 8 Q14249,O00311,Q9UJZ1,Q9ULV3,O95785 5 +Histone h3 k27 methylation 0.6597444177850939 2.085032469655269 0.0370663532959567 1.0 0.288809253419313 9 P16403,Q15910,P16402 3 +Rna localization 0.3724799782585495 2.078449255403534 0.0376680000892117 1.0 0.2907812475021192 121 O75152,Q9UKX7,Q9Y6M1,Q8WYP5,Q8TD16,P49790,Q92945,Q9NZI8,P12270,Q6P6C2,P55735,Q9H814,Q96PU8,Q86V81,P35658,Q14008,P25490,P06748,Q9NPE3,Q9HAU5,Q9NPA8,Q9BY77,Q13769,Q8NFH5,Q53F19,P82979,Q9H7Z3,Q9BZI7,P51991,O00159,Q96EE3 31 +Embryonic morphogenesis 0.3421682000231903 2.0716581076344536 0.0382973367553889 1.0 0.2942799605265828 89 Q13464,Q9BVC5,O95747,Q15648,Q92541,O15078,P07942,Q9P2D1,Q4VCS5,O14745,P62753,Q9UM54,Q13308,Q99496,P62081,Q12849,O75190,Q9Y366,P25440,Q8NCM8,Q8N3R9 21 +Plasma membrane repair 0.6356527426729236 2.068191134951104 0.0386220535463697 1.0 0.2950689457865998 10 Q9H444,Q9UQN3,Q9Y3E7,Q9HD42,P35579 5 +Cell cell junction organization 0.4001831212764635 2.06651995958439 0.038779409745401 1.0 0.2955931667321074 45 Q9Y490,Q13464,Q07157,O43815,Q9UDY2,Q16513,Q9Y2J2,Q16625,P55196,Q13112,O75116,P19022,P35611,O00159,P21333,Q15149,P18206 17 +Regulation of actin filament organization 0.3428408966615567 2.06193910829466 0.039213533588075 1.0 0.2985606408728636 76 Q9Y281,Q13464,Q9NWH9,Q96GD0,P35611,O60504,P62993,Q13136,P49593,Q13177,Q07157,P16949,Q9UJU6,O75146,Q13813,Q14247,O00165,P59998,Q7Z460,Q9UHB6,Q9Y6W5,Q9NYL9,Q01082,P60903,P42345,P14373,O75116,P47755,Q9UQB8,P21333,Q05655 31 +Regulation of ubiquitin protein transferase activity 0.4404466563597125 2.058286963480947 0.0395625948645692 1.0 0.2999562640175108 29 Q12834,Q13526,P62841,P62913,P62081,P46777 6 +Protein polymerization 0.3444423773955607 2.05813748828384 0.0395769372667955 1.0 0.2999562640175108 92 P46821,Q9NWH9,Q9Y3E7,Q9Y3E1,P51608,Q13049,Q13526,P16949,O75146,Q9BSJ2,Q13813,Q14008,Q14247,P59998,P0DMV9,Q9H444,Q14203,Q9P270,Q14980,Q9NYL9,Q9ULW0,Q01082,O60610,P42345,Q16625,P47755,Q9UQB8,Q08379,P23258 29 +Ncrna transcription 0.4436598588920311 2.054402941211027 0.0399367086380619 1.0 0.3019694413474086 27 Q7L2J0,Q13428,P42345,Q9NZM5,P19338,Q6P1N0,Q9Y5Q8 7 +Positive regulation of supramolecular fiber organization 0.3824296089126489 2.053263358451699 0.0400470425125725 1.0 0.3021442777109378 51 Q9Y281,P46821,Q96SN8,Q9NWH9,Q96GD0,P51608,O60504,P49593,Q14008,Q14247,P0DMV9,Q14203,Q7Z460,Q9P270,Q14980,Q9Y6W5,P60903,P42345,Q16625,Q9UQB8,P14373,O75116 22 +Rho protein signal transduction 0.454389639612247 2.0504831949053517 0.0403173020491853 1.0 0.3038392152168246 26 Q13464,Q12802,Q92888,P11274,Q9NWH9,P84095,Q07960,P16949,Q92974 9 +Regulation of actin filament based process 0.3498936682691753 2.048917796744894 0.0404701537841694 1.0 0.3041581055574865 98 Q9Y281,Q13464,P46108,Q9NWH9,Q96GD0,P35611,P46940,O60504,P62993,Q13136,P49593,Q13177,Q12802,P35241,Q07157,Q9Y5K6,Q04721,P16949,O75592,O75146,Q9UJU6,P15311,Q13813,Q14247,O00165,P59998,P84095,Q13045,Q7Z460,Q86VI3,Q9UHB6,Q9Y6W5,Q9NYL9,Q01082,Q14126,P35579,P60903,P42345,P14373,O75116,P47755,Q9UQB8,P21333,Q05655 44 +Endoderm development 0.586969497858836 2.0475523369391664 0.0406038836656965 1.0 0.3041581055574865 13 Q92541,P11047,P07942 3 +Spliceosomal complex assembly 0.4184897190498134 2.0466176161605727 0.0406956438209771 1.0 0.3041581055574865 37 Q13243,O95232,O75475,Q9ULR0,P16383,Q96SB4,O95319,O75494,Q15637,P62314,Q9BUQ8,Q92499,Q15459,Q9Y383,O94906,P62304,Q99590 17 +Endoderm formation 0.6728364397555349 2.0460289011034005 0.0407535272733272 1.0 0.3041581055574865 8 Q92541 1 +Endodermal cell differentiation 0.6728364397555349 2.0460289011034005 0.0407535272733272 1.0 0.3041581055574865 8 Q92541 1 +Protein demethylation 0.6726754621035957 2.045171103045928 0.0408379923173254 1.0 0.3043206989015906 8 Q9Y2K7 1 +Late endosome to vacuole transport 0.5460634493157339 2.0416750631157843 0.0411837739563338 1.0 0.3061729008978094 15 Q9NP79,Q9H444,Q9UQN3,Q9Y3E7,Q9HD42 5 +Microtubule depolymerization 0.5181469500485912 2.0400122264998872 0.0413491079857926 1.0 0.30641574794366 19 P46821,Q8WWK9,Q66K74,Q99661,Q9Y3E1,Q7Z460,P16949,Q92974,Q86Y91,Q9ULW0,O15344,Q14008 12 +Regulation of small gtpase mediated signal transduction 0.3975554210085095 2.036048650848224 0.0417454702161663 1.0 0.3086662847725864 45 A1A4S6,Q9NWH9,P46108,Q9H0H5,Q92974,Q8N6T3,O75955,Q12802,Q92888,Q4VCS5,Q04721,P16949,Q9Y5K6,Q5VZ89,Q15555,P50570,P11274,Q07960,Q12979 19 +Morphogenesis of an epithelium 0.3551219004061544 2.0349453112853424 0.041856376067213 1.0 0.3091432121505247 70 Q9NWH9,O95747,Q9UNS1,Q15648,O15078,P18206,P15311,O95487,O14745,Q13308,P62081,Q12849,P42345,Q9Y366,P78536,P25440,P21333,O94788,Q8N3R9 19 +Negative regulation of rna splicing 0.5317421558405249 2.029494908356223 0.0424079070691778 1.0 0.3118338597073541 17 P26599,Q08170,Q9BTD8,O75494,P38159,P98175 6 +Androgen receptor signaling pathway 0.5381590379486044 2.0283149208456344 0.0425281170898241 1.0 0.3121414739958475 16 Q9UER7,P82094,Q14151 3 +Response to steroid hormone 0.3406769894179313 2.028164623267033 0.0425434491726552 1.0 0.3121414739958475 76 P04083,Q14151,Q8TDD1,Q15648,P40818,Q9UER7,Q16576,P82094,O75528,O75592,P0DMV9,Q01664,Q96EB6,Q13185,O75874,P61353,Q9GZZ9,Q15424,P26583,P09874,P20020,Q9H7B4,P11142 23 +Cellular response to heat 0.451866309089008 2.0274238574372108 0.0426190841269042 1.0 0.312352407539534 26 Q9UER7,P0DMV9,P12270,Q16576,P42345,O75190,Q99543,P25685,Q96EB6,P55072 10 +Regulation of microtubule nucleation 0.7590307782783328 2.01253088744627 0.0441640040980835 1.0 0.3191112747304039 6 Q14008,Q14203,P51608 3 +Establishment of spindle orientation 0.5417772863778624 2.012026036837973 0.044217192424047 1.0 0.3191494430433388 15 Q96SN8,Q14203,Q7Z460,P27816,Q14980,Q9UNZ2,Q15334,P26367 8 +Protein transport within lipid bilayer 0.97629547960309 2.0032782469904147 0.0451474310196762 1.0 0.3231566297217307 2 Q9BRK0 1 +Stress granule assembly 0.5404767486401845 2.003015349949945 0.0451756409084538 1.0 0.3231566297217307 15 Q9Y520,Q14157 2 +Glomerulus development 0.7568240068473138 2.0022537214805616 0.0452574505449376 1.0 0.3231566297217307 6 O95747,P80723,Q04721,P11047 4 +Dna replication 0.3690678543558727 1.9967129747208068 0.0458563718530331 1.0 0.32669289524293 123 Q96ST3,Q8WVB6,Q14249,P11387,Q9Y5B9,Q99543,Q9ULV3,P54098,O75179,Q9UNS1,Q9NR30,P39748,Q7Z6E9,Q9HAF1,Q16576,P25205,O60934,Q9H981,Q86V81,P35251,Q96QE3,P25490,Q9UQE7,Q9NY93,P17096,Q9BRX5,Q9UJZ1,Q96EY1,O95785,Q13111,Q9NRL2,P33991,P54132,Q96T60,Q04837,Q13416,O00311,P49916,Q13112,Q9H1E3,Q9BUQ8,O75717,Q9NRF9 43 +Ribonucleoside diphosphate biosynthetic process 0.6631405594780688 1.9942419750545637 0.0461256170023975 1.0 0.3269030430531625 8 Q05682,P27144,Q9UIJ7 3 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.4287629210530084 1.9852058389187084 0.0471215749592239 1.0 0.3321946374374075 31 P62942,Q8NC56,P09874,Q9BRX2,Q13526,Q13573,Q04721,Q14980,Q96EB6,Q9Y2U8,P67870,P78536,P08238,Q8N3R9 14 +Positive regulation of microtubule nucleation 0.8170102254198044 1.9843902429534437 0.0472123528887264 1.0 0.3324827642121521 5 Q14008,Q14203,P51608 3 +Embryonic hindlimb morphogenesis 0.8780123919803838 1.9822649462450035 0.0474495951277749 1.0 0.3334485260983507 4 Q9P2D1,Q15648 2 +Hindlimb morphogenesis 0.8780123919803838 1.9822649462450035 0.0474495951277749 1.0 0.3334485260983507 4 Q9P2D1,Q15648 2 +Smooth muscle cell differentiation 0.660579091962717 1.9805202656870904 0.0476450984642151 1.0 0.3335039220147767 8 P26358,P51608,Q96EB6,O75179,P32929 5 +Negative regulation of supramolecular fiber organization 0.370438978874681 1.9782886517905456 0.0478961525934846 1.0 0.3339620848601473 58 P46821,Q8WWK9,Q9NWH9,Q9Y3E1,Q9UHV9,P35611,O15344,Q92974,Q13136,Q13177,Q07157,P16949,O75146,Q13813,O15212,Q9UHB6,Q9NYL9,Q01082,Q9ULW0,P47755,P11142 21 +Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.4301602152290809 1.97804429773454 0.047923709565641 1.0 0.3339620848601473 30 P62263,P82912,Q9BSC4,Q969X6,Q15050,O75691,P78316,Q9NSI2,Q14692,Q8N9T8,Q9NV06,Q2NL82,P39019,Q86U38,O15213 15 +Defense response to gram positive bacterium 0.8153680789606967 1.9772383381046257 0.0480146959423914 1.0 0.3342465040420189 5 P26583,P78536,Q96JM3 3 +Maturation of lsu rrna 0.4562385524271289 1.971995175431171 0.0486101572779269 1.0 0.3359345101509848 25 Q9H9Y2,Q8IY81,P62424,P55769,P46087 5 +Nucleus organization 0.3417913015504727 1.9692251423073523 0.0489272429281082 1.0 0.3377754325254478 74 Q8NC56,Q9UQN3,Q9Y3E7,Q8WYP5,Q15637,P49790,Q9HD42,Q9UN37,P12270,P82094,Q5JTV8,Q7Z3B4,Q9NZZ3,Q14203,Q9H444,Q14980,Q9UNZ2,Q96EB6,P02545,P39019,Q15149,Q8NFH5,P26583,Q14978,Q8NC51,Q96EE3 26 +Apical junction assembly 0.4927644847522485 1.967182530477495 0.0491621712731316 1.0 0.3380529307535458 21 Q13177,Q13464,Q07157,O43815,Q16513,Q16625,P55196,O75116,O00159,Q13112,P18206 11 +Protein localization to nucleoplasm 0.5926663482826928 1.9667166329054424 0.0492158882531152 1.0 0.3380529307535458 12 Q9NZM5 1 +Rrna modification 0.5294094699738918 1.9663537518577163 0.0492577617636418 1.0 0.3380529307535458 16 Q8WVM0,Q8IY81,Q9NPE3,O60832,P46087,Q9HC36 6 +Protein refolding 0.5924921386384346 1.9656461232238296 0.0493395023177971 1.0 0.3381684819353546 12 P62942,P0DMV9,P08621,P10809,P54652,P38646,P11142,P07900 8 +Protein localization to adherens junction 0.8123186776832205 1.963945596513483 0.0495364013200207 1.0 0.3391690704974086 5 Q13112,P18206 2 +Regulation of retinoic acid receptor signaling pathway 0.8118655531435996 1.9619690483218817 0.0497660878926158 1.0 0.3402889009855434 5 Q13573 1 +Glycine metabolic process 0.6566841988257002 1.95962339127504 0.050039825284744 1.0 0.3404793055560788 8 P00374 1 +Branching morphogenesis of an epithelial tube 0.5539363923652126 1.9587613349033637 0.0501407436618202 1.0 0.340507272451627 14 Q96T37,Q9UNS1,Q9NWH9,Q15648 4 +Regulation of platelet derived growth factor receptor signaling pathway 0.8720353006067296 1.957771665000514 0.0502568116792814 1.0 0.3409479423700334 4 O00291,O75146,O14745 3 +Protein localization to cell junction 0.4825560228225894 1.9538515822293656 0.050718771976405 1.0 0.3437319012276811 22 Q07157,Q9UDY2,Q9Y496,Q14168,Q9UQB8,Q13112,P33176,P18206 8 +Intracellular receptor signaling pathway 0.3618735258670401 1.9517466735686628 0.0509682882912876 1.0 0.3449379872465624 63 Q9UER7,P0DMV9,Q15424,Q15910,P82094,P09874,O75528,Q13573,Q9NZM5,Q14151,Q96EB6,Q8TDD1,O75179,Q15648,O94788,Q9GZZ9 16 +Positive regulation of dna replication 0.5209056039660759 1.950995606269168 0.0510575684531335 1.0 0.3449751734632616 17 Q14249,O00311,Q9UJZ1,Q9ULV3,O95785,Q9NRL2,Q96QE3 7 +Retinoic acid receptor signaling pathway 0.6540021306900966 1.945211287767936 0.0517495538496448 1.0 0.3474660217038853 8 Q13573,Q15910 2 +Cellular response to corticosteroid stimulus 0.5707923270962569 1.9444709105432123 0.0518386900088951 1.0 0.3474660217038853 13 Q01664,Q13185,P20020,Q9H7B4,P40818 5 +Startle response 0.9619625137816976 1.943520290604123 0.0519533262098093 1.0 0.3476887916152468 2 Q9HCK8 1 +Positive regulation of dna templated transcription elongation 0.5259684335644254 1.9419027942388736 0.0521488690839544 1.0 0.3479447265838764 16 P05114,O14776,O60885,Q9Y5B9,Q6P1J9,Q86V81,Q13769,P35269 8 +Megakaryocyte differentiation 0.5510400870479275 1.9394583875980256 0.0524455468087161 1.0 0.3479447265838764 14 P26583,Q8IZP0,Q96T37,Q15648,O95628,Q9GZZ9,P62805 7 +Meiotic cell cycle process 0.4012971550096822 1.9391508166893263 0.0524829764577903 1.0 0.3479447265838764 40 Q12834,P54652,Q08379,P35579,Q92878,Q9NQS7 6 +Histone h3 k4 methylation 0.4807120398589806 1.938726536873648 0.052534645574747 1.0 0.3479447265838764 22 P16403,P10412,P16402,P26358,Q13573,P18615,P51610,Q92541 8 +Maintenance of apical basal cell polarity 0.8659304986369492 1.9327026858223093 0.0532728341512389 1.0 0.3479447265838764 4 O14745 1 +Regulation of response to oxidative stress 0.4611415443961554 1.928142262773333 0.053837433418221 1.0 0.3509392779636768 24 P23246,Q14249,Q9NWH9,P09874,P00374,Q96EB6,Q9UMX0,Q15233 8 +Dna integrity checkpoint signaling 0.4102862501973146 1.9278008627332237 0.0538799003804792 1.0 0.3509392779636768 36 P16104,Q13564,Q96QC0,P61254,O60934,Q9NZM5,Q99459,Q9UNS1,Q14676,P54132 10 +Inner ear morphogenesis 0.599115459221319 1.9273017750814456 0.0539420325179833 1.0 0.3509392779636768 11 O14745,Q9P2D1,Q9UM54,Q13308,O95487,O15078 6 +Cytoplasmic translation 0.3579724284321047 1.925346667686318 0.0541860029360772 1.0 0.3521825868879478 115 P62913,P83731,Q9NZI8,P26373,P50914,P62917,P84098,P41214,P62841,Q02878,P47914,P46778,P62753,P23588,P61254,P62424,P62750,Q15056,P62273,P62081,P62899,P62857,P46777,P39019,P46779,P61353,P46782,P62263,P11940,P05387,P42345,P40429 32 +Nucleoside diphosphate biosynthetic process 0.6302116797218122 1.921048484094164 0.054725595346349 1.0 0.3546516694527015 9 Q05682,P27144,Q9UIJ7 3 +Late endosome to lysosome transport 0.6295233635341234 1.917198381924902 0.0552127335620702 1.0 0.3564217354559224 9 Q9HD42,Q9H444,Q9UQN3,Q9Y3E7 4 +Telomere organization 0.3506564998460599 1.9124813419089208 0.0558144835386742 1.0 0.3591567115688812 68 P84243,O60832,P49959,P18887,P39748,P62805,Q96QC0,O60934,Q8IY18,P22626,P27361,Q9NYB0,P35251,Q92878,P07900,Q00839,P09651,P07910,Q15910,Q9NPE3,P49750,Q9Y3C4,P28482,P13010,P54132,P08238,Q96T60,P50991,Q01780,P35244,P09874,Q9UBB9,Q92900,P78371,P17987 35 +Positive regulation of amyloid beta clearance 0.9545203969128994 1.9124027844309084 0.0558245511340405 1.0 0.3591567115688812 2 Q13464 1 +Telomere maintenance via recombination 0.8003827099872483 1.9117679788265225 0.0559059606569993 1.0 0.3591567115688812 5 Q92878 1 +Actin cytoskeleton reorganization 0.4269725453572491 1.9112877423903265 0.0559676134079047 1.0 0.3592063974214468 28 P04083,Q07157,Q13308,Q9Y5K6,P15311,P21333,Q9UQB8,P35579,Q15149,Q14247,Q9Y5S2 11 +Mrna 3 splice site recognition 0.7990000923351531 1.905708991467878 0.0566879720823298 1.0 0.3620855896572212 5 Q15637,Q15459 2 +Nephron epithelium development 0.5944009004498635 1.8990661230588783 0.0575557825992922 1.0 0.3644815757657537 11 Q04721,P11047,O95747,P80723,P46940 5 +Positive regulation of myeloid leukocyte mediated immunity 0.7344145922553957 1.8973473187526997 0.0577821136485936 1.0 0.3649492687762624 6 Q7Z434,Q12846,Q92499,Q9NR30 4 +Heart valve development 0.6899760235818196 1.8972596519492524 0.0577936773579941 1.0 0.3649492687762624 7 P42345,Q13464,P43243,Q04721 4 +Regulation of viral transcription 0.6446655698830263 1.8949019404116811 0.0581053940683462 1.0 0.3657615455053563 8 Q96T23,O60858,P14373,Q13049,O94992 5 +Embryonic appendage morphogenesis 0.5627068216213691 1.892623578323695 0.0584079458959427 1.0 0.3669678300124868 13 Q9P2D1,Q9Y366,O95747,Q15648,O94788,Q8NCM8 6 +Telomere capping 0.5626648546247972 1.8923539230188269 0.0584438408350718 1.0 0.3669678300124868 13 O60934,Q92878,P18887,Q96T60 4 +Positive regulation of mrna splicing via spliceosome 0.5127241872012249 1.8914198486125569 0.0585683210573293 1.0 0.3674031590244143 17 P08621,P19338,Q9Y2W1,Q13573,P98179,P38159,Q96E39 7 +Dna geometric change 0.3647627487042013 1.8896145424860753 0.0588095307909739 1.0 0.3680671058268164 57 Q8WVB6,Q13283,P04083,Q9P2D1,P26583,P25205,O60934,P13984,Q9BRX5,O15347,Q92499,Q9HCK8,P33991,P54132,Q92878 15 +Cellular response to dexamethasone stimulus 0.6883220179454959 1.8889455005733813 0.0588991317392473 1.0 0.3680671058268164 7 Q9H7B4,P40818,Q13185 3 +Cellular response to steroid hormone stimulus 0.3647085844390904 1.8889035826460836 0.0589047493378638 1.0 0.3680671058268164 57 Q9UER7,P0DMV9,Q15424,P04083,P82094,Q01664,P09874,O75528,Q14151,Q96EB6,Q13185,Q8TDD1,P20020,Q15648,Q9H7B4,Q9GZZ9,P40818 17 +Positive regulation of phosphatase activity 0.6422395805406667 1.8817948548989212 0.059863874669285 1.0 0.3719757780880843 8 Q13464,P42345,P17301,O14974,P08238,P0DP25 6 +Cell cell junction assembly 0.4161139152722902 1.881444785520002 0.0599114394909208 1.0 0.3719757780880843 32 Q9Y490,Q13464,Q07157,O43815,Q16513,Q9Y2J2,Q16625,P55196,O75116,P19022,O00159,Q13112,P18206 13 +Defense response to gram negative bacterium 0.8533351336888313 1.88081714317494 0.0599967973330062 1.0 0.3721589048719623 4 P26583,Q96JM3 2 +Skeletal muscle tissue regeneration 0.7299988018648559 1.8765616772484583 0.0605781939340051 1.0 0.3736777111003166 6 Q7Z4V5,Q15910 2 +Serine family amino acid catabolic process 0.8509449737248587 1.8709467445372885 0.0613524629722057 1.0 0.3767097772542255 4 P23378 1 +Histone h3 k27 trimethylation 0.789598816330223 1.8644298385491689 0.0622613658777924 1.0 0.3800035738324794 5 P16403,Q15910,P16402 3 +Regulation of clathrin dependent endocytosis 0.7273403609104214 1.8640305528992436 0.0623174138868365 1.0 0.3800035738324794 6 Q2M2I8,Q13432,Q8IYB5,O75146 4 +Response to vitamin d 0.7885272442266481 1.8597159991985104 0.0629257172322579 1.0 0.382491905293159 5 Q13573,Q15648 2 +Peptidyl lysine trimethylation 0.4868857828114654 1.8576803378771651 0.0632144223025639 1.0 0.3828495285269825 20 P16403,P10412,P16402,O60885,P51608,P02545,Q92541 7 +Striated muscle cell differentiation 0.3665377648062961 1.8539440812462935 0.0637471604797519 1.0 0.3843290344942148 51 Q9Y281,Q15014,O75147,Q12802,Q15910,P42345,Q9H7B4,Q9H4M9,O60271,Q15149,P19022,P02545,Q14315,Q13049,P35579,Q96HC4,P25490 17 +Actin filament based transport 0.6809324026575437 1.851730182618185 0.0640645776016783 1.0 0.3858935045048656 7 Q9UM54,O00159,O94832 3 +Nucleus localization 0.5182118006691632 1.8477599475524895 0.0646370774195586 1.0 0.3869300326278309 15 Q14203,P42345,Q15154,Q96N67,Q86VS8,O14745 6 +Mrna cis splicing via spliceosome 0.5066706723349439 1.8471759558463725 0.064721642933446 1.0 0.3869300326278309 17 O75475,Q9P013,Q13523,Q9Y2W2,Q9BUQ8,O43290,Q15459 7 +Positive chemotaxis 0.6357315018206354 1.8465638563923925 0.0648103765878569 1.0 0.3869300326278309 8 Q9NWH9 1 +Dna templated transcription initiation 0.3885364571186308 1.845116546592336 0.0650205867147319 1.0 0.3869300326278309 42 P35269,Q96T23,Q8WVM0,Q00059,P17480,P29083,Q14241,P13984,P53999,Q9NVC6,Q9Y5Q8,Q15648,O15160,P11802,Q9NYF8,P62805 16 +T cell chemotaxis 0.7850719729762154 1.844504246685525 0.0651096875038885 1.0 0.3869300326278309 5 O95747,P55011,P78536 3 +Lymphocyte chemotaxis 0.7850719729762154 1.844504246685525 0.0651096875038885 1.0 0.3869300326278309 5 O95747,P55011,P78536 3 +Embryonic organ development 0.3612358609439751 1.843279534694924 0.065288207591529 1.0 0.3869300326278309 57 O14745,Q7Z6E9,Q9Y3C6,Q9P2D1,Q9UM54,Q13308,O75190,Q12830,Q04721,Q9Y366,O95747,Q13043,Q15648,Q13769,O95487,O94788,P48681,O15078 18 +Sister chromatid segregation 0.3429911916426142 1.8427568928493443 0.0653645132448044 1.0 0.3869300326278309 104 Q9UQN3,Q12834,Q9Y3E7,Q99661,Q96EE3,Q9H0H5,Q13123,Q9HD42,Q15398,Q9UIG0,Q9UN37,P39748,Q7Z3K3,Q9Y448,P12270,Q13561,Q02241,Q9NTJ3,Q15050,Q96JM3,Q9NZZ3,Q00839,P23246,Q9Y6D9,Q9H444,Q9UQE7,Q14980,Q14807,Q53HL2,Q9Y6G9,Q9Y6A5,Q8WXW3,Q9HC35,Q86Y91,O75367,O95347,P23258,Q14683 38 +Epithelial cell morphogenesis 0.6779498866288195 1.8366777867379085 0.0662574763968872 1.0 0.3915784591304872 7 Q13464,Q9NWH9 2 +Tetrahydrofolate metabolic process 0.5954915162490921 1.835226257889329 0.0664721720803342 1.0 0.3918861084776963 10 P00374 1 +Regulation of wound healing 0.4983460547332875 1.8343765192359232 0.0665981226450505 1.0 0.3919405415736098 18 P80404,P04083,Q7Z460,P42345,P55011,Q16625,Q4KMQ2,P58107,Q05655 9 +Negative regulation of inclusion body assembly 0.8414230557087619 1.831550099194343 0.0670184771325832 1.0 0.3933486924692155 4 P25685,O75190,P54652 3 +Vesicle mediated transport between endosomal compartments 0.4500001115663496 1.8312112091906076 0.0670690242889653 1.0 0.3933486924692155 24 O60493,Q9Y3E7,P15311,Q15075,Q86VS8,P21333,O94832 7 +Signal transduction by p53 class mediator 0.365030262930878 1.8290995090434 0.067384702515278 1.0 0.39396953295979 50 Q01664,P61254,O60934,Q9NZM5,Q13573,Q9UM54,Q9BW85,P42345,P62913,P62841,P46087,Q15050,Q96EB6,P62081,P46777,Q96QE3 16 +Protein localization to cell cortex 0.7198783105969558 1.828787390065997 0.0674314647552472 1.0 0.39396953295979 6 Q14980,O43491 2 +Regulation of rho protein signal transduction 0.5341743154596061 1.8264845776377523 0.0677773022407073 1.0 0.3950414589042801 14 Q92974,Q12802,P16949,Q9NWH9 4 +2 oxoglutarate metabolic process 0.5936577934427943 1.8244825475238735 0.0680791524564297 1.0 0.3961076975237857 10 O75874,P36957,P48735,O43837 4 +Ribosomal subunit export from nucleus 0.5512723825015281 1.8189509660444991 0.0689189112229973 1.0 0.398840292029371 13 P06748,P62841,Q96GA3,Q9NVU7,Q86U38 5 +Positive regulation by host of viral transcription 0.629835049699897 1.81455857881811 0.0695917728422692 1.0 0.401750771815596 8 Q13573,Q01664 2 +Supramolecular fiber organization 0.4019076318471405 1.8132400456054212 0.0697948058673758 1.0 0.4018176947137259 203 Q9NWH9,Q96GD0,Q96AY3,Q05682,Q92974,Q12802,Q07157,Q15942,Q9BSJ2,O15212,O94832,P0DMV9,Q9P270,Q14980,Q9UHB6,Q01082,Q15149,Q16625,P14373,Q14315,Q9UQB8,O00159,Q96ED9,Q9Y281,Q13464,Q8IZP0,P51608,O75147,Q9Y5K6,Q86VS8,O43795,P84095,Q9NYL9,Q9ULW0,O60610,Q96JJ3,P47755,O75116,P11142,P23258,P46821,P07197,Q9Y3E1,Q9UHV9,P35611,O15344,Q13177,Q9ULV4,P16949,Q13813,O00165,P62942,Q9UM54,Q96IZ0,Q9Y6W5,Q8N8S7,P29966,Q16527,P08238,P60903,O75190,Q9H2G2,Q86Y91,Q08379,P21333,Q8WWK9,Q99661,P35221,O00151,O60504,Q13136,P49593,Q66K74,Q6WCQ1,Q13526,P49006,O75146,Q9UJU6,P15311,P50454,P13674,Q14008,Q14247,P67936,P59998,Q96CW5,Q14203,O00291,P58107,P42345 90 +Regulation of histone h3 k9 methylation 0.6109075879674505 1.8126123634211115 0.0698916295806204 1.0 0.4018176947137259 9 P26358,P02545,P51608 3 +Cortical actin cytoskeleton organization 0.4649058323035004 1.8084578742102624 0.0705352675080512 1.0 0.4026627891717513 22 Q13464,O43491,Q9Y2J2,Q9H0H5,Q5VSL9,P15311,Q9UN37,Q9Y490 8 +Positive regulation of transcription elongation from rna polymerase ii promoter 0.6282845157429167 1.806129291242566 0.0708981464572897 1.0 0.4026627891717513 8 O14776,O60885,Q9Y5B9,Q6P1J9,P35269 5 +Positive regulation of response to cytokine stimulus 0.566569814048291 1.805331907102066 0.0710227595594485 1.0 0.4029264769466781 12 P78536,Q15648,Q7Z434,Q13049,Q9NZI8 5 +Regulation of endothelial cell differentiation 0.6274534942772394 1.8016093207441808 0.0716068937784604 1.0 0.4046509189644184 8 O75116,Q13464,P18206,O14974 4 +Lysosomal membrane organization 0.928059536934954 1.8013068894892117 0.0716545225488696 1.0 0.4046509189644184 2 Q9UQN3 1 +Regulation of muscle cell differentiation 0.4170226265697456 1.801187169169781 0.0716733840255199 1.0 0.4046509189644184 27 P26599,Q15014,Q15910,P42345,P26358,P51608,O75179,Q13049,P25490 9 +Negative regulation of ubiquitin protein ligase activity 0.6087287029618803 1.8003151596779552 0.0718108885262696 1.0 0.4050839452684234 9 P61927,O95816,Q13257,P62841,P62913,P62081,P46777 7 +Skeletal muscle organ development 0.4464170654748406 1.7999181559955937 0.071873562372009 1.0 0.4050944775992591 24 Q9Y281,Q8NC56,O75446,P80723,Q7Z406,O75369,Q15149,Q9Y5Q8 8 +Cellular response to interferon gamma 0.455248790791384 1.7988966598844205 0.0720350290578966 1.0 0.405227543887673 23 Q12846,Q15942,P04406,Q16543,O75369,P40429,Q15648,P08238,O00159,P33176 10 +Regulation of smooth muscle cell differentiation 0.6703965472938527 1.7984768575804628 0.0721014727950259 1.0 0.405227543887673 7 P26358,P51608,Q96EB6,O75179,P32929 5 +Regulation of double strand break repair 0.3944620850373183 1.7908329154892189 0.0733201115043806 1.0 0.4071200290147405 37 Q7Z3K3,Q15014,Q9HAF1,P09874,Q9NPF5,Q7Z4V5,Q9UNS1,P61088,Q96T60,Q15906 10 +Negative regulation of telomere maintenance 0.5764121040467718 1.7907571133251492 0.0733322801437417 1.0 0.4071200290147405 11 O60934,Q92878,P09874,P18887 4 +Cell substrate junction organization 0.4070558714042795 1.7902424240079098 0.0734149477159884 1.0 0.4071200290147405 32 Q9Y490,Q13464,P60903,P18206,P11274,Q9ULV4,P11047,Q15555,Q9H2G2,O75116,Q15149,Q14247,P49593 13 +Actin filament based process 0.3975678235213614 1.789522540763792 0.0735307006548615 1.0 0.4071200290147405 194 Q9NWH9,Q96GD0,Q05682,Q7Z406,Q13049,Q92974,Q9UN37,Q9UNF0,Q12802,Q07157,Q15942,Q9NVU7,O94832,Q9UHB6,Q01082,Q15149,Q9NR12,P14373,Q14315,Q5M775,Q9UQB8,O00159,Q9Y281,Q13464,P04083,Q8IZP0,Q96HC4,O75147,Q9Y5K6,Q04721,Q9Y5S2,O43795,Q9Y490,P11274,P84095,Q13308,Q9NYL9,P35579,O60610,Q96JJ3,P47755,O75116,Q9Y2J2,Q9H0H5,Q5VSL9,P35611,P46940,P46939,Q13177,Q92614,Q9ULV4,Q4VCS5,P16949,O75592,Q13813,O14745,O00165,O43491,Q9UM54,Q96IZ0,Q9Y6W5,Q8N8S7,O75369,P29966,P35580,Q16527,O75190,P21333,Q13136,Q6WCQ1,P49006,O75146,P15311,Q14247,P59998,Q86VI3,O00291,P42345 78 +Positive regulation of telomere maintenance 0.415779722003253 1.7892780111597173 0.0735700535033465 1.0 0.4071200290147405 27 P09651,P50991,Q96QC0,O60934,O60832,P28482,P49959,P13010,P78371,P22626,P27361,P17987,Q92878,Q96T60 14 +Regulation of circadian rhythm 0.4127086637761286 1.7892324890555689 0.073577381407047 1.0 0.4071200290147405 29 Q96ST3,Q15910,P42345,Q9Y2W1,Q8WXF1,Q15233,Q9UNS1,Q9Y2K7 8 +Cell cycle checkpoint signaling 0.3577366419755486 1.7853322403447511 0.0742074423280549 1.0 0.4096390427867485 56 P16104,Q13564,Q96QC0,P12270,Q9Y6D9,P61254,O60934,Q9NZM5,Q99459,Q13123,Q9UNS1,Q14676,P54132,Q9UN37 14 +Cell differentiation involved in metanephros development 0.8301291229278509 1.784671030376593 0.0743146925588513 1.0 0.4096390427867485 4 P11047 1 +Metanephric nephron development 0.8301291229278509 1.784671030376593 0.0743146925588513 1.0 0.4096390427867485 4 P11047 1 +Negative regulation of small gtpase mediated signal transduction 0.5631202618560579 1.7838529603106108 0.0744475612375716 1.0 0.4096390427867485 12 Q9Y5K6,Q9NWH9 2 +Ventricular trabecula myocardium morphogenesis 0.923649393605303 1.782727027812527 0.0746307494338813 1.0 0.4099581151603938 2 Q9P2D1 1 +Non membrane bounded organelle assembly 0.3838632801652784 1.7769996403852164 0.0755682989988635 1.0 0.4137205414521898 165 Q9Y281,Q8WWM7,Q13283,Q9UQN3,Q12834,Q9Y3E7,Q9H0H5,P62913,P46087,P83731,Q7Z4H7,Q96CS2,Q14157,Q8IY37,Q9HD42,Q15398,P26038,Q7Z3K3,Q12802,O75147,P12270,Q9NZM5,Q02241,P62841,Q15050,Q9UJU6,Q15555,P15311,Q02878,Q9BSJ2,Q9Y520,Q9NZZ3,Q9NQS7,Q00839,P06748,P0DMV9,Q9H444,Q14137,Q96CW5,P82912,Q9UQE7,Q14980,P62750,Q9Y2R9,Q9H3R5,Q9NYL9,P62857,Q9ULW0,Q16527,P39019,P46777,Q15149,Q7L2E3,P46782,P62263,Q96PK6,Q8WXW3,Q14315,Q9UN86,Q08379,P21333,Q14683 62 +Negative regulation of viral transcription 0.7087544897973113 1.7760654852721225 0.0757221242539278 1.0 0.4139367256444892 6 P14373,O60858,O94992,Q13049 4 +Negative regulation of mrna catabolic process 0.4523749198995341 1.7744456262172952 0.07598946850552 1.0 0.4139367256444892 23 P11940,Q6PKG0,Q9Y2W1,Q13151,P98175 5 +Positive regulation of multicellular organism growth 0.622211910856186 1.7730647923287808 0.0762179711787598 1.0 0.4142744601742573 8 Q9P2D1 1 +Negative regulation of dna dependent dna replication 0.8265697683613314 1.7698640595738429 0.0767497892727653 1.0 0.4148217883448305 4 P49916,Q9UNS1 2 +Substrate adhesion dependent cell spreading 0.4333815562999771 1.767151081553442 0.0772029296664573 1.0 0.4148217883448305 25 P60903,P46108,Q9ULV4,Q14155,P11047,P21333,P50570,Q9NVD7,P06756,O43707,P07942 11 +Nucleolar large rrna transcription by rna polymerase i 0.5421652220968147 1.7599960409910342 0.0784084778380529 1.0 0.4185375524882955 13 P42345,Q9NZM5,Q13428,P19338 4 +Tricarboxylic acid metabolic process 0.6014345255607801 1.759067169113531 0.078566100475069 1.0 0.4185375524882955 9 P48735 1 +Tight junction organization 0.4882568502481734 1.7585630722129628 0.0786517498449475 1.0 0.4185375524882955 18 Q13464,Q07157,O43815,Q16625,P55196,O75116,O00159,Q13112,Q15149 9 +Regulation of helicase activity 0.6011963860606235 1.7577184468613545 0.0787954275170552 1.0 0.4185375524882955 9 Q04837,P52701,P49736,Q96EB6,Q9Y3Y2,P20585,P04637 7 +One carbon metabolic process 0.5588833625166292 1.757427991416139 0.0788448856758947 1.0 0.4185375524882955 12 P13995,P00374,Q6UB35,Q9NZL9,Q9H9B4,P31153 6 +Aorta development 0.6622109442408162 1.7569523420807114 0.0789259328124698 1.0 0.4186342073221927 7 Q96AY3 1 +Regulation of non motile cilium assembly 0.6188386763104696 1.7546632714367765 0.0793169219415736 1.0 0.4197523704282457 8 P27816,Q9UHD8,Q15555 3 +Histone h3 k4 trimethylation 0.5813753356745064 1.752300104473553 0.0797222180967076 1.0 0.4206583314872115 10 P16403,Q92541,P16402 3 +Dna dependent dna replication maintenance of fidelity 0.5045987231565146 1.751975665935349 0.0797779922849266 1.0 0.4206583314872115 15 Q86V81,Q9UNS1,Q9H1E3 3 +Appendage development 0.4803477788379472 1.7509639659944491 0.0799521171717649 1.0 0.4207066539351324 19 Q9P2D1,O75592,Q9Y366,O95747,Q15648,Q8NCM8 6 +Regulation of cellular response to heat 0.6180342947599 1.7502716589701286 0.080071448853793 1.0 0.4207066539351324 8 P42345,O75190,P25685,Q99543 4 +Ribosomal small subunit export from nucleus 0.6176874577004974 1.748377640760418 0.0803986569924588 1.0 0.421138162104475 8 Q96GA3,Q86U38,P62841 3 +Regulation of cell shape 0.4023887429255453 1.7430923955422315 0.0813174767276425 1.0 0.4242263351288604 32 P04083,O75400,P84095,Q9UEE9,Q9Y2J2,P15311,Q7Z406,P35580,Q9UQB8,P35579,O14745 11 +Antimicrobial humoral response 0.7007207323480342 1.7378573041404106 0.0822359604624289 1.0 0.426252711560555 6 P39019,P05204,Q96JM3 3 +Negative regulation of telomere capping 0.9542321477805348 1.7371225197789104 0.0823655471638478 1.0 0.426252711560555 3 Q92878,P18887 2 +Regulation of response to dna damage stimulus 0.3164648963220873 1.736872317381296 0.0824097106709689 1.0 0.426252711560555 84 Q15014,Q14249,Q9NPF5,P18887,Q9UNS1,Q13049,Q7Z3K3,Q96QC0,Q9HAF1,Q7Z4V5,P61088,Q9NYB0,Q96QE3,P16104,P61254,Q96EB6,Q13769,Q9NYF8,Q96T60,P09874,Q15906 21 +Centrosome separation 0.7000142527736428 1.7344922083809513 0.0828307870447537 1.0 0.4269953259170834 6 Q9UNZ2 1 +Regulation of keratinocyte differentiation 0.5965860151834633 1.7315822311955482 0.0833479721624388 1.0 0.4273956465775701 9 Q13464,Q9P0M6,Q14980,Q15648 4 +Rrna methylation 0.5773814024818045 1.728748978136314 0.0838540313458469 1.0 0.4287093676121579 10 P46087,Q9HC36,Q8WVM0,Q8IY81 4 +Histone lysine demethylation 0.6987256987344739 1.728352493492614 0.0839250471288335 1.0 0.4287093676121579 6 Q9Y2K7 1 +Epithelial tube morphogenesis 0.3820584911630642 1.7263059780842631 0.0842923804522861 1.0 0.429634333497654 40 Q96T37,Q9NWH9,Q13308,Q04721,Q9Y366,O95747,Q13043,P62081,Q9UNS1,Q15648,P25440,O95487,O15078 13 +Centriole centriole cohesion 0.75828253805054 1.725967256852728 0.084353303544721 1.0 0.429634333497654 5 Q9BV73,Q14203 2 +Positive regulation of tumor necrosis factor mediated signaling pathway 0.6980544664753657 1.7251531363486283 0.0844998786704167 1.0 0.4300520945013876 6 Q13049,P78536 2 +Ribosome biogenesis 0.4001922161503256 1.7233303807249658 0.084828796780247 1.0 0.4310674631197602 217 Q9GZR2,Q8WVM0,Q9BSC4,O60832,Q14331,Q9Y237,P62913,P46087,Q8TDD1,P83731,Q9Y3C1,Q2NL82,Q9NV06,Q9Y3B9,Q9HC36,Q9NR30,P50914,Q9P2D1,Q96DE0,O43709,Q9NZM5,P62841,Q15050,Q9H6R4,O75683,Q02878,Q9NVU7,Q9UHA3,Q99547,Q96GQ7,Q9BVJ6,O43290,O15213,P62753,P06748,P46777,Q14137,Q14690,P82912,Q8IY81,P62424,Q9NPE3,P61254,Q9NY93,P62750,Q76FK4,Q99848,Q969X6,O43818,P78316,P62081,Q9NSI2,Q9H501,Q5T3I0,Q9Y2R9,Q8N9T8,Q5JTH9,P62857,P39019,Q9ULX3,Q7L2E3,P61353,Q86U38,Q9H9Y2,P46782,P62263,O00566,P55769,Q9Y2W2,Q96GA3,Q969S3,Q14978,Q14692,O75691,Q8NEF9,P62847 76 +Forelimb morphogenesis 0.757432425845475 1.722189227423138 0.085035245650721 1.0 0.4314583446497362 5 O95747 1 +Embryonic forelimb morphogenesis 0.814681318083208 1.720299134621786 0.085378080685136 1.0 0.431554456391788 4 O95747 1 +Positive regulation of response to wounding 0.5942474217343703 1.7183068666530612 0.0857406575592703 1.0 0.4324029225282806 9 P42345,Q16625,P04083,P21333 4 +Mitotic dna integrity checkpoint signaling 0.4538359561905348 1.716623905736979 0.08604791168375 1.0 0.4334465144953598 22 Q13564,Q96QC0,P61254,O60934,Q9NZM5,Q14676 6 +Ear morphogenesis 0.4817588179778229 1.7095562140206342 0.087347968325548 1.0 0.4381868712234947 18 O14745,Q9P2D1,Q9UM54,Q13308,O95747,O95487,O15078 7 +Activation of innate immune response 0.4604309794524013 1.7068550174122057 0.0878490034261896 1.0 0.4395341421953904 21 Q96ST3,P23246,Q96PK6,Q8WXF1,P43243,Q7Z434,O60828,O94992,Q9NZI8,Q15233 10 +Protein k63 linked deubiquitination 0.5921332806992279 1.7062955269275808 0.0879530704980693 1.0 0.4395341421953904 9 Q9NZM5,P40818 2 +Regulation of mrna metabolic process 0.3737117503691095 1.7042457953457146 0.0883351768948292 1.0 0.4395341421953904 155 Q13464,Q9NWH9,Q6PKG0,Q13573,Q05655,O75150,O95319,Q14151,P38159,P98179,Q96E39,Q15637,P18583,Q92945,P09012,Q9NZI8,P26599,O75175,P52272,Q8IY67,Q6P6C2,Q9Y2W1,Q6P1J9,Q9UNW9,Q8IZD4,P98175,Q96PU8,Q6PJT7,Q00839,P06748,Q96T37,Q08170,P08621,P19338,Q9BTD8,Q13151,Q07666,Q13310,Q14498,Q15424,P11940,Q8N684,Q8N7H5,Q15007,Q15287,Q01130,P18615,Q96SB4,O75494,P49756,Q8NC51,P52758,O00267,O75116,P11142,P84103 56 +Regulation of cell morphogenesis 0.3266718438397619 1.7039443142016886 0.0883914910625494 1.0 0.4395341421953904 73 P04083,Q9Y2J2,O60271,Q5VSL9,Q9NZM3,Q7Z406,P26038,O75147,O75400,Q9ULV4,Q14444,P15311,Q9UJU6,O14745,P84095,P35580,P35579,O60610,P60903,Q9UEE9,Q9UQB8,Q5VZL5,P21333 23 +Establishment of epithelial cell apical basal polarity 0.692682477004388 1.699522271550405 0.0892208218526999 1.0 0.440941480105851 6 Q13308,O14745 2 +Positive regulation of mrna processing 0.4593868803514959 1.6983838446729025 0.0894353392108309 1.0 0.4410086670940892 21 P08621,P19338,Q13573,Q9Y2W1,Q6P1J9,P98179,Q96E39,P38159,P11142 9 +Negative regulation of fibroblast proliferation 0.6506149273665529 1.6979140899974683 0.0895239775333627 1.0 0.4410086670940892 7 Q13049,Q96IZ0,Q71SY5,P50402 4 +Regulation of guanyl nucleotide exchange factor activity 0.8093101392616514 1.697852995583658 0.0895355106755535 1.0 0.4410086670940892 4 Q9NWH9 1 +Negative regulation of muscle cell differentiation 0.5481378800656398 1.6902051416619233 0.0909887150574637 1.0 0.4424609173953263 12 P26599,Q15910,P51608,O75179,P25490 5 +Isocitrate metabolic process 0.6883703454155556 1.6789156874573523 0.093168476727512 1.0 0.4468598934187799 6 P48735 1 +Actin filament depolymerization 0.4491804317254236 1.6778741207786054 0.0933716756235685 1.0 0.4471905844746323 22 Q9Y281,Q96GD0,Q9UHB6,Q13813,Q9NYL9,Q01082,P47755 7 +Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.4936392697239775 1.674446746285309 0.0940428321792774 1.0 0.4497047939960609 15 P09874,Q9BRX2,Q14980,Q13573,Q04721,P67870,P78536 7 +Tube morphogenesis 0.3449673722426862 1.6718897813270852 0.0945460581871497 1.0 0.4504199099709182 118 Q13464,P04083,Q9NWH9,P55011,P51608,Q96AY3,O95747,Q05682,Q9UNS1,Q15648,O15078,Q9UII2,Q9P2D1,Q07157,Q4VCS5,Q04721,Q96JM3,Q13043,P19022,Q96PU8,Q5JRA6,O95487,Q96T37,P19338,Q13308,Q96EB6,Q9UGM6,P62081,O14964,P35579,Q12904,Q9Y366,P67870,P25440,O96013,P21333 36 +Cytoskeleton dependent intracellular transport 0.3371286305231767 1.6696335857202371 0.0949918811994168 1.0 0.451703006816927 66 P46821,Q13409,Q9UPN4,P23246,Q14203,Q8TD16,O94832,Q9UM54,Q9Y496,Q9Y366,Q96ED9,Q14168,O00159,Q86VS8,Q8NCM8,P11142,P33176,O43795 18 +Cellular response to stress 0.2239820481288474 1.6682950355524258 0.0952571729559559 1.0 0.4523241963522731 518 Q96ST3,Q9GZR2,Q9NWH9,O60858,P00374,P54098,P20585,Q14676,Q13049,Q92974,Q9NZI8,Q15233,Q7Z6E9,P52272,P25205,Q9NZM5,O15027,P25685,Q7Z4V5,Q9H981,P61088,Q92878,Q9Y2K7,P25490,P06748,P0DMV9,P23246,Q13111,P54132,Q13769,Q15149,Q9NYF8,Q5SSJ5,P55072,Q9NXW2,Q9NRF9,Q96EE3,Q15906,Q15014,P04083,Q14249,O60885,Q13573,Q99543,P18887,Q6ZXV5,Q9Y4L1,Q9UIG0,Q9UII2,Q9UER7,Q7Z3K3,P12270,Q16576,O60934,Q8NBM4,P31689,Q16543,Q9NYB0,P33908,Q15910,P61254,P17096,P30040,Q99459,P11047,Q96EB6,Q14807,Q9H078,Q9H8Y8,Q9C0J8,P26583,P78540,O95793,Q9BW85,Q15291,Q9H7Z3,Q969S3,Q13438,P22314,O75116,P11142,P45973,P13667,Q9NPF5,O75915,Q9HAF1,Q9NXV6,Q96QE3,P16104,Q9UM54,Q13185,P11166,O00311,O75190,P54652,P21333,Q14683,Q04323,P27144,P10586,O95747,Q7Z6Z7,Q9UNS1,P39748,Q96QC0,P15311,Q9UMX0,Q01664,Q9UQE7,P02545,P30101,P33991,Q9GZZ9,Q96T60,Q92575,P09874,P42345,P49916,Q9H1E3,Q92499,Q13112 121 +Serine family amino acid metabolic process 0.4875984693071775 1.6664133228230378 0.0956311190292302 1.0 0.4528034932286653 16 P23378,P00374 2 +Cellular response to interleukin 1 0.5271913933523245 1.6625777957368724 0.0963969788447649 1.0 0.4545865604748454 13 P38159,Q02952,Q9NZI8,Q96JM3 4 +Regulation of supramolecular fiber organization 0.3435157182300326 1.662015711093537 0.0965096243619418 1.0 0.4546824610362147 117 Q9Y281,P46821,Q13464,Q8WWK9,Q9NWH9,Q96GD0,Q9Y3E1,P51608,Q9UHV9,P35611,O60504,Q92974,O15344,Q13136,P49593,Q13177,Q12802,Q07157,Q66K74,P16949,O75146,Q9UJU6,Q13813,O15212,Q14008,O00165,Q14247,P59998,P0DMV9,Q14203,Q9P270,Q14980,Q9UHB6,Q9Y6W5,Q9NYL9,Q9ULW0,Q01082,P60903,P42345,Q16625,P14373,O75116,P47755,Q9UQB8,P21333,P11142 46 +Heart valve morphogenesis 0.7438488985435875 1.6616949504187608 0.0965739541228225 1.0 0.4546824610362147 5 P42345,Q13464,Q04721 3 +Mesenchymal cell proliferation 0.8001963429492408 1.659695404837145 0.0969757442691445 1.0 0.455232008944177 4 O95747 1 +Granulocyte activation 0.5655696196352781 1.6588864345679066 0.0971386786720147 1.0 0.455232008944177 10 Q12846,P04083,P11274,Q96JM3,Q05655,P51809 6 +Nuclear transcribed mrna catabolic process deadenylation independent decay 0.7960646053827226 1.642368516054451 0.1005136555846581 1.0 0.4655426114263781 4 Q6P2E9 1 +Positive regulation of protein localization to cell cortex 0.7960591504843808 1.6423456291406069 0.1005183959090469 1.0 0.4655426114263781 4 Q14980 1 +Metanephric glomerulus development 0.8900220507166481 1.6405552702362842 0.1008897665024934 1.0 0.4655426114263781 2 P11047 1 +Negative regulation of sodium ion transmembrane transport 0.8900220507166481 1.6405552702362842 0.1008897665024934 1.0 0.4655426114263781 2 O14745 1 +Microtubule anchoring at microtubule organizing center 0.6393471137476291 1.6403235083632068 0.1009379202223841 1.0 0.4655426114263781 7 Q8TD16,Q86VS8,Q14203 3 +Positive regulation of dna recombination 0.400218284104645 1.6396015907820998 0.101088032132119 1.0 0.4655426114263781 27 Q15014,Q9HAF1,Q9NPF5,Q7Z4V5,Q9UNS1,Q96QE3,Q15906 7 +Inner ear auditory receptor cell differentiation 0.6384466608303481 1.635712315474343 0.101899810764199 1.0 0.466247623153224 7 Q9UM54,O14745 2 +Embryonic organ morphogenesis 0.3991910972002711 1.629689129032622 0.1031672161020871 1.0 0.4705784261079956 27 O14745,Q9P2D1,Q9UM54,Q13308,Q04721,Q9Y366,O95747,O95487,O15078 9 +Establishment of epithelial cell polarity 0.5605660288657697 1.629202594388889 0.1032701379420428 1.0 0.4705784261079956 10 O14745,Q13308,Q92614 3 +Cellular response to vitamin d 0.7927563156924511 1.628482736216908 0.1034225669061117 1.0 0.4709508822477897 4 Q13573,Q15648 2 +Actin filament based movement 0.4175512300768119 1.623963932353205 0.1043835064390412 1.0 0.4734259816012279 25 Q13464,Q9UM54,Q7Z406,P35580,O00159,P35579 6 +Polarized epithelial cell differentiation 0.594322926791792 1.6202372163241303 0.1051813297502066 1.0 0.475708091511118 8 Q13308,O14745 2 +Nuclear pore organization 0.520637059134399 1.6197653185106984 0.1052826989275921 1.0 0.4758435144203655 13 P12270,Q8WYP5,P49790,Q96EE3,Q8NFH5 5 +Respiratory burst 0.7343682221617505 1.6193389669202995 0.1053743508934434 1.0 0.4759348648488953 5 P39019,P18669 2 +Forebrain development 0.3334432883222911 1.6171443321456522 0.1058471293389606 1.0 0.477409536376519 66 Q96ST3,P16104,Q9P2D1,Q15910,P11166,Q9Y6A5,Q8NCM8,P25685,P19022,Q8N3R9,P18887,O94788,Q86VS8,Q15042,Q9NZI8,P07942 16 +Peptidyl lysine acetylation 0.3462688998220926 1.6168151618972764 0.1059181856014523 1.0 0.477409536376519 54 Q96ST3,Q15014,Q9HAF1,Q9UPT9,Q9NPF5,P51610,P51608,Q9NPA8,Q9BX68,Q9NRF9,Q6ZRS2,Q15906 12 +Regulation of protein localization to centrosome 0.7895837239430665 1.615156713456245 0.1062767618506059 1.0 0.4778090383836905 4 Q9UNZ2 1 +Dna strand elongation involved in dna replication 0.53618123179063 1.6150893212078306 0.1062913531799203 1.0 0.4778090383836905 12 P49916,Q9NRF9,P33991 3 +Regulation of endothelial cell development 0.6341276795572744 1.6135775063331568 0.1066190991171933 1.0 0.4786364139614165 7 O75116,Q13464,P18206,O14974 4 +Positive regulation of cell cycle g2 m phase transition 0.5025469573756653 1.61231507449888 0.1068933946337753 1.0 0.4793512201182696 14 P06748,Q96ST3,O00311,O60885,P51608,P54652,Q96QE3 7 +Blastocyst growth 0.5753580086248241 1.6106682775727914 0.1072520433991464 1.0 0.4795390020973915 9 Q92541 1 +Hair cell differentiation 0.557040267399626 1.60825636085308 0.1077790439449011 1.0 0.4802836058601547 10 Q9UM54,O14745 2 +Positive regulation of cell aging 0.6734579191789144 1.6074426321113156 0.107957304408397 1.0 0.4804723728283082 6 P02545,P78540,Q96EB6 3 +Muscle tissue development 0.3421575506195016 1.6031173362822606 0.1089087512142006 1.0 0.4827345978636091 58 Q9Y281,Q8NC56,O95747,Q7Z406,Q15648,Q96HC4,P50402,Q9P2D1,O75147,Q12802,O75446,Q04721,P25490,P62942,P02545,O75369,Q15149,P42345,O94788,Q9Y5Q8 20 +Mitotic cell cycle checkpoint signaling 0.3689309670762928 1.6003619036897487 0.1095183213221433 1.0 0.4847913997661919 41 Q13564,Q96QC0,P12270,Q9Y6D9,P61254,O60934,Q9NZM5,Q13123,Q14676,Q9UN37 10 +Glyoxylate metabolic process 0.9172101296429834 1.5939833789740476 0.1109397576918269 1.0 0.4872061516455125 3 P48735 1 +Negative regulation of cell cycle process 0.3128723454631252 1.590915960969162 0.1116284900320103 1.0 0.4872061516455125 76 P06748,P16104,Q13564,Q96QC0,P12270,Q15910,Q9Y6D9,P61254,O60934,Q9NZM5,Q96PK6,Q99459,Q13123,Q9UNS1,Q14676,P54132,Q9UN37 17 +Myeloid dendritic cell cytokine production 0.7276398355998366 1.5892177585674503 0.1120112385190137 1.0 0.4872061516455125 5 Q7Z434,Q92499,Q9NR30 3 +Dendritic cell cytokine production 0.7276398355998366 1.5892177585674503 0.1120112385190137 1.0 0.4872061516455125 5 Q7Z434,Q92499,Q9NR30 3 +Positive regulation of dendritic cell cytokine production 0.7276398355998366 1.5892177585674503 0.1120112385190137 1.0 0.4872061516455125 5 Q7Z434,Q92499,Q9NR30 3 +Positive regulation of rna splicing 0.430685256668552 1.5889718210340615 0.1120667547317844 1.0 0.4872061516455125 23 P08621,P19338,Q13573,Q9Y2W1,P24928,P98179,Q96E39,P38159,P11142 9 +Glomerular epithelial cell differentiation 0.7832322118036316 1.5884503998064412 0.1121845284783416 1.0 0.4872061516455125 4 P80723,Q04721,P11047 3 +Glomerular epithelium development 0.7832322118036316 1.5884503998064412 0.1121845284783416 1.0 0.4872061516455125 4 P80723,Q04721,P11047 3 +Signal transduction in response to dna damage 0.3543462693970263 1.5881770738721122 0.1122463037636563 1.0 0.4872061516455125 47 P16104,Q96QC0,Q01664,P61254,O60934,Q9NZM5,Q9UM54,Q99459,Q96EB6,Q14676,P54132,Q13769,Q96QE3 13 +Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway 0.78300149089078 1.587479611349979 0.1124040611046461 1.0 0.4872061516455125 4 Q9H444 1 +Dna templated transcription elongation 0.3566431738686575 1.5849153529998643 0.1129855677559164 1.0 0.4890902224755783 46 O60885,Q9Y5B9,P13984,O15160,Q92541,Q14241,Q6P1J9,Q86V81,P35269,Q00839,Q15910,P05114,O14776,Q9NPA8,Q13769,Q8N7H5,P18615,O94992,Q5BKZ1 19 +Lamellipodium morphogenesis 0.5878121029891453 1.5843526555461762 0.1131134894491121 1.0 0.4893260173441462 8 Q9Y6W5,Q9ULV4,Q13596,Q8IZP0 4 +Negative regulation of epithelial cell differentiation 0.7257753781745568 1.5808625753430523 0.113909463013355 1.0 0.4911746554012758 5 Q15910 1 +Appendage morphogenesis 0.4749719985044889 1.5748036172512356 0.1153017812292809 1.0 0.4949358676220808 16 Q9P2D1,Q9Y366,O95747,Q15648,O94788,Q8NCM8 6 +Negative regulation of phosphatidylinositol 3 kinase signaling 0.7794573396200264 1.5725614246092257 0.1158204057437279 1.0 0.4958840251058585 4 Q9NZM5 1 +Regulation of epidermis development 0.5289999193702735 1.5698325026077802 0.1164540838411813 1.0 0.4976510460998269 12 Q13464,Q15910,Q14980,Q15648 4 +Negative regulation of mitotic cell cycle 0.3425332418027554 1.5684588171598108 0.1167740938351062 1.0 0.4976510460998269 54 Q13564,Q96QC0,P12270,Q15910,Q9Y6D9,P61254,O60934,Q9NZM5,Q13123,Q14676,Q9UN37,O14745 12 +Regulation of mirna transcription 0.6249781729961095 1.566595621680521 0.1172092419027528 1.0 0.4976510460998269 7 Q96KM6 1 +Neuronal stem cell population maintenance 0.7224827586206534 1.5660987499964183 0.1173255007004705 1.0 0.4976510460998269 5 Q9BXP5,Q86VS8,P19022,Q9NZI8 4 +Regulation of platelet derived growth factor receptor beta signaling pathway 0.8723814773980161 1.5656933571782348 0.1174204221735348 1.0 0.4976510460998269 2 O75146 1 +Positive regulation of platelet derived growth factor receptor signaling pathway 0.8723814773980161 1.5656933571782348 0.1174204221735348 1.0 0.4976510460998269 2 O75146 1 +Transcription by rna polymerase iii 0.4499412647677482 1.5653505672089092 0.1175007324085615 1.0 0.4976510460998269 20 Q8WUA4,P42345,Q9HCK8,Q9Y5Q8,O15160,Q9NR30,Q9UIG0 7 +De novo pyrimidine nucleobase biosynthetic process 0.7218616423167503 1.5633125099758929 0.1179791072502518 1.0 0.4990328968261446 5 Q05682 1 +Negative regulation of platelet derived growth factor receptor signaling pathway 0.8715545755237035 1.5621808002518076 0.118245402317318 1.0 0.4998324354875207 2 O14745 1 +Endothelial cell development 0.4349919111915546 1.5593926022065057 0.1189034861663924 1.0 0.5005743021456835 22 Q13464,Q07157,Q9NWH9,Q9UDY2,P55196,P15311,O14974,O75116,P18206 9 +Response to interferon gamma 0.4005529066769729 1.551513365199749 0.1207787069419463 1.0 0.5047852858514722 26 Q12846,Q15942,P04406,Q16543,O75369,P40429,Q15648,P08238,P19474,P07814,O00159,P33176 12 +Regulation of dna templated transcription elongation 0.3880683722622753 1.5471535491001165 0.1218262238911038 1.0 0.5058743452098456 29 Q15910,P05114,O14776,O60885,Q9Y5B9,Q6P1J9,P18615,Q86V81,Q13769,P35269,Q5BKZ1,Q00839,O94992 13 +Negative regulation of viral process 0.4407742488702064 1.5468616942957276 0.1218965996447116 1.0 0.5058743452098456 21 O60493,Q7Z434,O60858,Q96SB4,Q12906,P14373,Q13049,O94992 8 +Cellular response to vitamin 0.6606894514873425 1.546009126447964 0.1221023637192182 1.0 0.5058743452098456 6 Q13573,Q15648 2 +Nuclear membrane reassembly 0.4755243718903836 1.5456216783824532 0.1221959625453612 1.0 0.5059474844482267 15 Q9H444,Q9UQN3,Q9Y3E7,Q9UNZ2,Q9HD42,Q9UN37 6 +Histone h3 acetylation 0.4599624879088606 1.54432582636443 0.1225094190105486 1.0 0.5060400635055019 18 Q96ST3,Q9HAF1,Q9UPT9,O75528,Q9NPA8,Q9NRF9 6 +Positive regulation of histone h3 k4 methylation 0.5243738611299057 1.540629517575499 0.1234069796871542 1.0 0.5076263996103556 12 Q92541,P51610,P18615,Q13573 4 +Regulation of chromatin organization 0.4651253385078429 1.540389325122663 0.1234654818953722 1.0 0.5076263996103556 17 Q96ST3,P12270,Q66K74,P46013,Q13263,P26358,Q8NEY8,O75367,Q00839 9 +Muscle organ morphogenesis 0.7165024811186926 1.5392567501918264 0.1237416280430787 1.0 0.5076263996103556 5 Q9P2D1 1 +Cardiac muscle tissue morphogenesis 0.7165024811186926 1.5392567501918264 0.1237416280430787 1.0 0.5076263996103556 5 Q9P2D1 1 +Ventricular cardiac muscle tissue morphogenesis 0.7165024811186926 1.5392567501918264 0.1237416280430787 1.0 0.5076263996103556 5 Q9P2D1 1 +Response to chemokine 0.7163655454084418 1.5386417342794063 0.1238917839937505 1.0 0.5076263996103556 5 O95747,P55011 2 +Nuclear migration 0.4915408320302157 1.5372162820002646 0.124240354449072 1.0 0.5084086249015465 14 Q14203,Q15154,Q96N67,Q86VS8,O14745 5 +Dna ligation involved in dna repair 0.865490628445425 1.5364146688775366 0.1244367113412514 1.0 0.5088995524588196 2 Q96T60 1 +Tetrahydrobiopterin metabolic process 0.7698435932414434 1.5320437322822769 0.1255116433534706 1.0 0.5123520637382484 4 P00374 1 +Negative regulation of cell cycle phase transition 0.3273397194358097 1.5301753808185885 0.1259733235133107 1.0 0.513477589704502 66 P16104,Q13564,Q96QC0,P12270,Q15910,Q9Y6D9,P61254,O60934,Q9NZM5,Q99459,Q13123,Q9UNS1,Q14676,P54132,Q9UN37 15 +Constitutive heterochromatin assembly 0.6572619737070695 1.529485201155248 0.1261442050006442 1.0 0.513477589704502 6 Q7Z7K6,Q9NRZ9,Q15910 3 +Establishment or maintenance of monopolar cell polarity 0.5437951324295468 1.5293700086385098 0.1261727430720909 1.0 0.513477589704502 10 O14745,P46821,Q13308,P15311 4 +Pore complex assembly 0.4899611246270583 1.5264188536339045 0.1269055852251308 1.0 0.5152011022363325 14 Q8WYP5,P12270,P49790,Q5EBL8 4 +Regulation of cell cycle g2 m phase transition 0.3747298724309857 1.5257538124582783 0.127071187318148 1.0 0.5155592265003058 35 Q96ST3,P06748,Q13564,O60934,Q9NZM5,O00311,P51608,P54652,P54132,Q96QE3,Q9UN37 11 +Gastrulation with mouth forming second 0.7678732806259908 1.5237311124803885 0.127575894087258 1.0 0.5172919089527163 4 Q4VCS5 1 +Histone deubiquitination 0.5325070291550034 1.5231398298751837 0.1277237258566121 1.0 0.5175763148763688 11 Q99496,Q9NPA8,Q9UPT9 3 +Regulation of dna templated transcription initiation 0.4892018193690846 1.5212274662846847 0.1282027651167365 1.0 0.5188131575320772 14 P53999,Q9NVC6,Q15648,P11802,Q9NYF8 5 +Mesonephros development 0.6156212186942057 1.518432510400104 0.1289054011883865 1.0 0.5199012789059179 7 O95747,P80723 2 +Negative regulation of actin filament depolymerization 0.462090228906119 1.5178108215021913 0.1290620962721855 1.0 0.5201522597491229 17 P35241,Q9UHB6,P35611,Q13813,Q9NYL9,Q01082,P47755 7 +Virion assembly 0.4502494162861526 1.5173895330053295 0.1291683650338611 1.0 0.5202658088606907 19 Q9NP79,Q9H444,Q9UQN3,Q9Y3E7,Q9HD42,Q9UN37 6 +Antimicrobial humoral immune response mediated by antimicrobial peptide 0.711156553560087 1.515234398186086 0.1297130548413145 1.0 0.5217628204255247 5 P39019,P05204,Q96JM3 3 +Positive regulation of histone h3 k9 methylation 0.7111021451546065 1.5149897830563324 0.1297749915108217 1.0 0.5217628204255247 5 P02545,P51608 2 +Nadp metabolic process 0.4665635371757863 1.5136088904087224 0.1301250649380678 1.0 0.5225708899162453 16 O75874,P29401,P48735 3 +Telencephalon development 0.3427667315717403 1.5128141715054673 0.130326868061146 1.0 0.5230346957972016 49 P16104,Q9P2D1,Q15910,P11166,P19022,P18887,Q9Y6A5,Q8N3R9,P07942 9 +Transcription initiation from rna polymerase i promoter 0.6535282663288097 1.5114703177048954 0.1306686655405018 1.0 0.523145823215639 6 P17480,Q9UIF9,O15160 3 +Rna polymerase i preinitiation complex assembly 0.6535282663288097 1.5114703177048954 0.1306686655405018 1.0 0.523145823215639 6 P17480,Q9UIF9,O15160 3 +Regulation of histone h3 k4 methylation 0.4873337620448394 1.5084516072219265 0.1314389833012832 1.0 0.5246098677758323 14 Q92541,P51610,P18615,Q13573 4 +Response to vitamin 0.4656577973018341 1.5070098125495164 0.1318081420363004 1.0 0.5251829200034889 16 Q13573,Q01130,P20020,Q15648,O94788 5 +Nucleoside monophosphate phosphorylation 0.652461679235819 1.5063214210715683 0.131984681725088 1.0 0.5255719962059393 6 P27144,Q9UIJ7 2 +Regulation of oxidative stress induced cell death 0.4356883266823833 1.5053240679797455 0.1322407803163543 1.0 0.5259630319209269 21 P23246,Q14249,Q9NWH9,P09874,Q96EB6,Q9UMX0,Q15233 7 +Odontogenesis 0.5396808601557914 1.5048091840305655 0.13237314189645 1.0 0.5261509762916304 10 P07942,O75592,P04920 3 +Purine nucleoside diphosphate biosynthetic process 0.7632509221246332 1.5042190734689531 0.1325249682103506 1.0 0.5261509762916304 4 P27144,Q9UIJ7 2 +Adp biosynthetic process 0.7632509221246332 1.5042190734689531 0.1325249682103506 1.0 0.5261509762916304 4 P27144,Q9UIJ7 2 +V d j recombination 0.6127098572336982 1.5034252851051009 0.1327294103476937 1.0 0.526648797937067 7 P49916,P26583 2 +Mitotic sister chromatid cohesion 0.4862143706076499 1.5007933997530207 0.1334090063476525 1.0 0.5287155266437008 14 Q14683,Q9UQE7,Q12834 3 +Mitotic nuclear division 0.3470238735467786 1.4993944397243877 0.1337713352133387 1.0 0.5293845944006332 134 Q96SN8,P46013,Q9UQN3,Q96GD0,P18754,Q12834,Q9Y3E7,Q9H0H5,Q99661,P23258,Q13123,P83731,Q96Q89,Q9HD42,Q15398,Q9UN37,Q9UIG0,O00139,Q7Z3K3,O75147,P12270,Q9Y448,Q13561,Q13526,Q02241,Q9NTJ3,Q9Y266,Q15050,Q96JM3,P43487,Q9NZZ3,Q00839,P0DMV9,Q9H444,Q9Y6D9,Q9UQE7,Q7Z460,Q14980,Q9UNZ2,Q99640,Q14807,Q53HL2,Q9ULW0,Q9Y6G9,Q9Y6A5,Q8WXW3,Q9HC35,Q86Y91,O75367,Q08379,P21333,O95347,Q96EE3,Q14683 54 +Axon development 0.3031108730962806 1.4990197922520012 0.1338684975522404 1.0 0.5293845944006332 85 Q96ST3,P46821,Q9BVA1,P00374,P10586,Q9Y4W6,P83731,Q96N67,P35221,Q13049,P33176,P18206,Q13177,Q13740,Q66K74,Q04721,P16949,O75592,Q9UJU6,Q9UNW9,P19022,Q14247,P84095,Q9BPU6,P11047,Q8N8S7,P08238,Q9H2P0,P53990,Q9UQB8,P21333 31 +Intrinsic apoptotic signaling pathway in response to oxidative stress 0.4595628406872633 1.498997939734901 0.1338741665422396 1.0 0.5293845944006332 17 P23246,P09874,Q969S3,O75915,Q9UMX0,Q15233 6 +Negative regulation of lymphocyte activation 0.453712888612522 1.496763491572582 0.134454808988345 1.0 0.5305118295656024 18 P04083,Q9Y6D9,P78540,Q96IZ0,O15347,P30511 6 +Regulation of mitochondrial dna replication 0.7614451185879743 1.496592504971083 0.1344993215455272 1.0 0.5305118295656024 4 P49916,Q14249,Q9UJZ1 3 +Negative regulation of transcription by rna polymerase i 0.7613479800656754 1.4961821944206322 0.1346061832395348 1.0 0.5305482328423864 4 Q9NZM5,P21333 2 +Telomere maintenance 0.326317359560297 1.49559330939324 0.1347596677337454 1.0 0.5305482328423864 65 O60832,P49959,P18887,P39748,Q96QC0,O60934,Q8IY18,P22626,P27361,Q9NYB0,P35251,Q92878,P07900,Q00839,P09651,P07910,Q9NPE3,P49750,Q9Y3C4,P28482,P13010,P54132,P08238,Q96T60,P50991,Q01780,P35244,P09874,Q9UBB9,Q92900,P78371,P17987 32 +Negative regulation by host of viral transcription 0.7057213028311744 1.4907861253140835 0.1360176556434096 1.0 0.5327158270995854 5 Q01664,Q9H1E3 2 +Regulation of protein localization to cell cortex 0.7051217122281501 1.4880876890872723 0.1367277696825939 1.0 0.5340371068344462 5 Q14980 1 +Transcription elongation from rna polymerase ii promoter 0.3790161093248012 1.4879813021551989 0.1367558247162361 1.0 0.5340371068344462 31 P35269,Q15910,O14776,O60885,Q8N7H5,Q9Y5B9,P13984,Q14241,Q6P1J9,Q9NPA8,P18615,Q92541,Q00839,O94992 14 +Positive regulation of dna templated transcription initiation 0.5159836270081604 1.4875783555789206 0.1368621250296853 1.0 0.5341391194773073 12 P53999,Q9NYF8 2 +Cell cycle process 0.3415470904577372 1.4864072460440008 0.1371714343524086 1.0 0.5347197751057615 383 Q96ST3,Q9UPN4,P46013,Q12834,Q96GD0,Q8WYP5,P83731,Q96CS2,Q14676,Q9UN37,Q13564,P25205,Q9NZM5,O14974,Q9BSJ2,P43487,Q92878,P48681,Q9NQS7,P06748,P0DMV9,Q7L2J0,Q9Y6D9,P23246,P27816,Q14980,Q9UNZ2,Q9BRX5,P54132,Q01082,Q13769,Q15149,Q13432,P53990,P55072,Q96EE3,Q13464,P04083,Q9UQN3,O60885,P51608,Q9HD42,Q9UIG0,P40818,Q7Z3K3,O75147,P12270,O75400,O60934,Q02241,Q14141,Q15050,Q96JM3,Q9BV73,Q9NZZ3,Q9H444,Q15910,P61254,Q99459,Q96EB6,Q99640,Q9H3R5,Q14807,Q9NYL9,Q9ULW0,P35579,P78536,Q9Y3E7,Q9H0H5,O75179,Q15648,Q9Y448,P16949,Q96QE3,P16104,P35580,Q15019,Q96PK6,O00311,P54652,Q08379,P21333,O95347,Q8NBT2,Q14683,Q9NQG5,Q8WWK9,Q16513,P18583,Q13123,Q9UNS1,Q15398,P39748,Q96QC0,Q13526,P15311,Q7Z7K6,Q14008,P62753,Q14203,Q01664,Q9UQE7,Q86VI3,O95785,P02545,P33991,Q9Y6A5,Q9HC35 108 +Response to mineralocorticoid 0.6092819254808101 1.485743315537395 0.1373470286636813 1.0 0.5347401062358621 7 P20020,P61353,P09874 3 +Mrna 3 end processing 0.3604495643719059 1.485477227334991 0.1374174514974175 1.0 0.5347401062358621 40 Q9NQG5,Q96P16,O75150,P09012,Q05048,Q6P1J9,Q9P2I0,Q6PJT7,Q5VTR2,Q5VT52,Q9C0J8,P11940,Q8N684,Q12849,Q8N7H5,P18615,P33240,O00267,O94992,Q6UN15 20 +Cell part morphogenesis 0.34678221158698 1.4834961183693949 0.1379426469866875 1.0 0.5360941305567827 135 Q96ST3,P46821,Q13464,Q8IZP0,Q9BVA1,Q9Y2J2,O60271,Q9NZM3,Q9Y4W6,Q7Z406,P83731,Q96N67,P46940,Q96Q89,Q6SZW1,Q9NZI8,Q96HC4,Q9UNF0,O75955,P18206,Q13177,Q13740,O75147,P33176,Q66K74,Q9ULV4,Q04721,Q14444,P16949,Q9GZT3,O75592,Q9UJU6,P19022,Q9UNW9,P50570,Q9Y639,Q8WX93,P48681,P07900,Q14247,P84095,Q8TB37,Q9BPU6,P11047,Q9Y6W5,Q8N8S7,P08238,Q9H2P0,Q15149,Q9GZY8,Q04837,P51956,Q9ULH0,Q9UQ16,Q9BRT6,Q13596,P53990,Q9UQB8,O60828 59 +Positive regulation of cell cycle checkpoint 0.6469993671595375 1.4799346855868751 0.1388906780062759 1.0 0.5360941305567827 6 Q9Y6D9 1 +Hepatocyte growth factor receptor signaling pathway 0.6468903694387513 1.479407861709821 0.1390313402265759 1.0 0.5360941305567827 6 Q9NWH9 1 +Endosome transport via multivesicular body sorting pathway 0.4568498746236197 1.4787934632728852 0.1391955234333719 1.0 0.5360941305567827 17 Q9NP79,Q9H444,Q9UQN3,Q9Y3E7,P55072,Q9HD42 6 +Multivesicular body sorting pathway 0.4568498746236197 1.4787934632728852 0.1391955234333719 1.0 0.5360941305567827 17 Q9NP79,Q9H444,Q9UQN3,Q9Y3E7,P55072,Q9HD42 6 +Nucleosome mobilization 0.5248647961146523 1.476194375902428 0.1398917189183701 1.0 0.5360941305567827 11 Q9NRF9,Q12830,Q9H981,P25490 4 +Vesicle uncoating 0.7561308039936986 1.4741365176174497 0.1404448380248151 1.0 0.5360941305567827 4 P11142,Q9UN37 2 +Cellular response to potassium ion 0.75569164598925 1.4722800843660575 0.1409452590454254 1.0 0.5360941305567827 4 P55011,Q9NXV6 2 +Response to potassium ion 0.75569164598925 1.4722800843660575 0.1409452590454254 1.0 0.5360941305567827 4 P55011,Q9NXV6 2 +Monoubiquitinated protein deubiquitination 0.5129771532218395 1.4685450191293123 0.1419562369365361 1.0 0.5360941305567827 12 Q99496,Q9NPA8,Q9UPT9 3 +Negative regulation of nucleocytoplasmic transport 0.6053325578680542 1.465356683146779 0.1428236290676547 1.0 0.5367591644192993 7 P49790 1 +Positive regulation of epithelial cell proliferation 0.3820877165553085 1.4642405318311764 0.143128239274155 1.0 0.5367591644192993 27 P26583,Q86VI3,Q04721,P11047,O95747,Q15648,P78536,P07942 8 +Attachment of spindle microtubules to kinetochore 0.448881231075508 1.4599540855960569 0.1443026931517295 1.0 0.5395980452150536 18 Q9Y448,Q9Y6D9,Q9H0H5,Q9HC35,Q96JM3,Q8NBT2 6 +Regulation of transcription of nucleolar large rrna by rna polymerase i 0.5321399506562962 1.4597339858687408 0.1443631976125523 1.0 0.5395980452150536 10 P42345,Q9NZM5,P19338 3 +Cell cycle dna replication 0.4366688529059723 1.4594972322982185 0.1444283018475101 1.0 0.5395980452150536 20 P25205,O00311,Q9BRX5,O95785,P33991,Q96QE3,P39748 7 +Positive regulation of cytokine production 0.3208756341766685 1.4588192378371068 0.1446148662329887 1.0 0.5397334671395915 67 Q9BY67,Q13283,P04083,P30511,Q13049,Q92974,Q9NR30,P82094,P0DMV9,Q9NY93,Q96EB6,Q9UJZ1,Q01082,Q7Z434,P04406,P26583,O14802,P14373,Q92499,P78536,O75116,O60828,Q02952 23 +Positive regulation of defense response to virus by host 0.6424720882530831 1.45804382282673 0.1448284642438388 1.0 0.5399257016186092 6 Q7Z434,O60828 2 +Regulation of dna dependent dna replication 0.4073886021076881 1.4562279168884869 0.1453296245848248 1.0 0.5414910285145988 24 Q8WVB6,Q14249,O60934,O00311,P49916,Q9BRX5,Q9UJZ1,Q9ULV3,O95785,Q9UNS1,P54132 11 +Regulation of sodium ion transmembrane transport 0.4790373712193591 1.4516522310299758 0.1465983278803373 1.0 0.5435708462385016 14 P46939,O14745,P05026 3 +Copii coated vesicle cargo loading 0.5305881092413705 1.450449638474404 0.1469331733948189 1.0 0.5435708462385016 10 O95486,P55735,Q15437,Q5JRA6,O95487,O94979 6 +Pteridine containing compound biosynthetic process 0.5634319559689456 1.44943782503645 0.1472153518709293 1.0 0.5435708462385016 8 Q6UB35,P11586,P00374,P09417 4 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.3333124280720706 1.4490708196173374 0.1473178061070554 1.0 0.5435708462385016 54 Q8NC56,Q9BRX2,Q13573,Q9Y4E8,Q13526,Q04721,Q9Y2U8,Q15942,P50570,P53999,P62942,Q14980,Q96EB6,Q01082,P08238,Q96PK6,P09874,P67870,P78536,Q6PIU2,Q8N3R9 21 +Basement membrane assembly 0.6963504506766234 1.4485836051729817 0.1474539024278498 1.0 0.5435708462385016 5 P07942 1 +Regulation of early endosome to late endosome transport 0.5095078603091148 1.4465685314429373 0.1480178050947755 1.0 0.5435708462385016 12 O60493,P35241,Q9Y3E7,P15311,Q9UMY4,O75165,P27361,P26038 8 +Actomyosin contractile ring organization 0.6958944481591555 1.4465284595192958 0.148029035594907 1.0 0.5435708462385016 5 Q9H0H5,Q9UN37 2 +Regulation of vitamin d receptor signaling pathway 0.8792052342182692 1.4463124362575708 0.1480895891806934 1.0 0.5435708462385016 3 Q13573 1 +Vitamin d receptor signaling pathway 0.8792052342182692 1.4463124362575708 0.1480895891806934 1.0 0.5435708462385016 3 Q13573 1 +Positive regulation of dna binding 0.4521283620400455 1.4436093269361905 0.1488488998395167 1.0 0.5435708462385016 17 P18074,P07305,P26583,P09874,Q13263,P09429,O60869,P17301,P0DP25,P26367 10 +Spindle localization 0.4211445058286885 1.443363487277874 0.1489181040478122 1.0 0.5435708462385016 22 P27816,Q14980,Q9UNZ2,P35579 4 +Cellular sodium ion homeostasis 0.7487815613276656 1.4430558250190997 0.1490047460069399 1.0 0.5435708462385016 4 P05026 1 +Cellular potassium ion homeostasis 0.7487815613276656 1.4430558250190997 0.1490047460069399 1.0 0.5435708462385016 4 P05026 1 +Negative regulation of t cell receptor signaling pathway 0.7483271057587071 1.441132995795639 0.149547113391824 1.0 0.5441195354540316 4 P15311 1 +Negative regulation of antigen receptor mediated signaling pathway 0.7483271057587071 1.441132995795639 0.149547113391824 1.0 0.5441195354540316 4 P15311 1 +Negative regulation of mirna transcription 0.841786108048536 1.4356132197642035 0.1511124309112061 1.0 0.5470623863624106 2 Q96KM6 1 +Vasculature development 0.3225686915757724 1.434605613172678 0.1513995141659256 1.0 0.5470623863624106 109 Q13464,P04083,P55011,P51608,Q96AY3,O95747,Q05682,O75179,Q15648,Q9UII2,Q9P2D1,Q07157,Q4VCS5,Q04721,Q96JM3,Q13043,P19022,Q96PU8,Q5JRA6,O95487,Q96T37,P19338,Q13308,P26358,Q96EB6,Q9UGM6,O14964,P35579,Q12904,O94788,O96013,P21333,Q8NCM8 33 +Heat acclimation 0.8409592061742167 1.4320960058912993 0.1521163473897351 1.0 0.5483761397783633 2 Q16576 1 +Negative regulation of circadian rhythm 0.8406835722160966 1.4309236061196138 0.1524521107272636 1.0 0.5489395140648697 2 Q96ST3 1 +Platelet aggregation 0.4914962712094363 1.4284622134609914 0.1531588632689593 1.0 0.5494584529336602 13 P35579,P18206,Q9Y490 3 +Positive regulation of helicase activity 0.6915204294619273 1.4268090434746863 0.1536349437650181 1.0 0.5500737281936157 5 Q9Y3Y2,P20585 2 +Negative regulation of guanyl nucleotide exchange factor activity 0.8740913776077248 1.4264115380372029 0.1537495851433443 1.0 0.5500737281936157 3 Q9NWH9 1 +Cellular response to retinoic acid 0.5431766553060869 1.4259288725060564 0.1538888742757329 1.0 0.5500737281936157 9 O95747,Q13308,Q13573 3 +Positive regulation of myeloid cell differentiation 0.4439209732304651 1.4221398635878697 0.1549856522938903 1.0 0.5508011108801352 18 P0DMV9,P26583,Q8IYB5,Q9UKV3,Q04721,Q15648 6 +Erythrocyte development 0.5424097386303042 1.421511237651888 0.1551681889666392 1.0 0.5508011108801352 9 P18074,Q7L5Y9,Q9NX58,Q9NYL9,Q15648,P62753 6 +Nucleobase containing small molecule interconversion 0.634733229391808 1.4205850535323334 0.1554374261775146 1.0 0.5511038494915395 6 P27144,Q9UIJ7 2 +Regulation of protein complex stability 0.6338772366694531 1.4164390501706423 0.1566469974499424 1.0 0.5545070653621237 6 Q9UIL1,P11142 2 +Voluntary musculoskeletal movement 0.7416378207222483 1.412819776977577 0.1577087216974997 1.0 0.5570813912771703 4 P18887 1 +Ribonucleoprotein complex biogenesis 0.3816281489424436 1.412066655790471 0.1579303356476908 1.0 0.5570869787138478 296 Q9GZR2,O95319,P83731,Q2NL82,Q9Y3B9,Q9HC36,Q9P2D1,Q9NZM5,P62841,Q9NVU7,O43290,Q99590,P06748,Q9ULR0,Q8IY81,P62424,Q9NPE3,P62750,Q99848,P78316,P62081,Q9ULX3,Q7L2E3,Q9H9Y2,O43395,O75494,Q9Y2W2,Q96GA3,P40429,Q8NEF9,Q9BSC4,O60832,Q9Y237,Q15637,Q8TDD1,Q9NR30,O43709,Q15050,Q9UHA3,P82912,P61254,P16383,Q76FK4,Q969X6,O43818,Q9NSI2,Q9H501,Q5JTH9,P61353,P46782,P62263,O00566,Q9BW85,Q969S3,Q14978,Q14692,O94992,Q15459,Q14331,P62913,P46087,P50914,Q13243,Q96DE0,Q9H6R4,O75683,P62314,Q9BVJ6,Q14137,Q14690,O95400,Q9NY93,Q5T3I0,Q15056,Q9Y2R9,Q8N9T8,P62857,P08238,P39019,Q9Y383,Q86U38,Q96SB4,P55769,Q9BUQ8,O75691,P62847,Q8WVM0,Q9Y3C1,Q9NV06,P41214,Q02878,Q99547,Q96GQ7,O15213,P62753,P23588,O95232,P46777,O75475,Q9UHI6,Q92499 101 +Cellular component assembly involved in morphogenesis 0.3942451054294196 1.4119619393904377 0.1579611682363342 1.0 0.5570869787138478 25 Q9Y281,O75147,Q12802,P82094,Q13045,Q7Z460,Q9Y2J2,Q14315,Q8N3R9,Q9NYL9,Q16527,Q15149 12 +Positive regulation of phosphoprotein phosphatase activity 0.6325701355239617 1.4101071581063305 0.1585080439720816 1.0 0.5581513419729651 6 P42345,P0DP25,P08238,O14974 4 +Response to interleukin 7 0.5237987363690026 1.4098022156630268 0.1585980922177758 1.0 0.5581513419729651 10 P54727,O14908,P31948,P30101,P51858 5 +Replication fork protection 0.8354465270121265 1.4086489395483082 0.1589390001012469 1.0 0.5590557648756638 2 Q9UNS1 1 +Nuclear body organization 0.8693506059398532 1.4079599380907548 0.1591429330703619 1.0 0.5591826055457549 3 Q15637 1 +Establishment of endothelial barrier 0.441948934668574 1.4071012221660075 0.1593973757728801 1.0 0.5594864685979597 18 Q13464,Q07157,Q9UDY2,P55196,P15311,O14974,O75116,P18206 8 +Epidermal cell differentiation 0.3562015460406001 1.405908488104068 0.1597513004922746 1.0 0.5601385073050176 38 Q13464,P04083,Q15910,P11274,Q9UM54,Q14980,Q13043,Q9P0M6,O75369,Q15648,O95487,Q15149,O14745 13 +Basement membrane organization 0.5933906842565625 1.4036290183185662 0.1604293493709454 1.0 0.5622200555019665 7 P07942 1 +Regulation of cell cycle process 0.3792490422516748 1.4015970433290037 0.1610356104137311 1.0 0.5640479687572434 209 Q96ST3,Q9NQG5,Q9UPN4,P04083,P46013,Q9UQN3,Q12834,Q8WYP5,Q96GD0,O60885,P51608,Q9Y3E7,Q9H0H5,Q16513,Q13123,O75179,Q9UNS1,Q14676,Q15648,Q9HD42,Q15398,Q9UN37,Q9UIG0,P39748,Q13564,O75147,P12270,O75400,Q9Y448,Q96QC0,O60934,Q9NZM5,Q13526,Q02241,Q9BV73,P43487,Q7Z7K6,Q9NZZ3,Q96QE3,P06748,P16104,P0DMV9,P23246,Q7L2J0,Q9Y6D9,Q9H444,Q15910,P61254,Q14203,Q14980,Q01664,Q9UNZ2,Q99459,Q96EB6,Q99640,O95785,Q9NYL9,P54132,Q9ULW0,Q13769,Q9Y6A5,Q96PK6,O00311,P54652,P78536 65 +Negative regulation of rho protein signal transduction 0.685821435781479 1.40110086241745 0.1611839137602322 1.0 0.5640754946974202 5 Q9NWH9 1 +Positive regulation of wound healing 0.5544602162869066 1.3996247917365323 0.1616257059451675 1.0 0.5645184777222024 8 P42345,Q16625,P04083 3 +Response to epidermal growth factor 0.4408805930347316 1.398953309244534 0.1618269848806166 1.0 0.5646809564455336 18 P19338,P12270,Q15648 3 +Tricarboxylic acid cycle 0.4084524405273658 1.3977190895880074 0.1621974394572296 1.0 0.5654418323726133 23 P40925,O43837,P31040,Q96I99,P53597,P11177,Q02218,O75874,P36957,P48735,Q99798 11 +Regulation of metaphase plate congression 0.6290901236482582 1.3932439656833084 0.1635460288210293 1.0 0.5683587084015114 6 Q9Y6D9 1 +Regeneration 0.36177478787993 1.3892677821529458 0.1647513369676634 1.0 0.5710579640367188 35 P46821,P04083,Q15910,Q9HAU5,P00374,P10586,P62841,P11047,Q7Z4V5,Q15648,P58107,P21333 12 +Regulation of potassium ion transport 0.4697759770941137 1.3881603468606851 0.1650882239101005 1.0 0.5719281059225638 14 O95747,P21333,P05026 3 +Regulation of protein import 0.3914523173298065 1.386518333895301 0.1655886859315383 1.0 0.573363734758788 25 P12270,P11142,Q7Z434,Q9NPF5,Q9NW64,P21333,Q14978,P08238,Q7Z3B4,O14737,O95071,Q05655 12 +Positive regulation of cell cycle phase transition 0.337394989371565 1.3828597560018894 0.1667078721175707 1.0 0.5748487805627622 47 Q96ST3,P06748,Q96QC0,P04083,Q7L2J0,Q15910,O00311,P51608,P54652,Q13769,O75179,P78536,Q15398,Q96QE3 14 +Positive regulation of cytokine production involved in immune response 0.484283350700094 1.3809493937656316 0.1672945211931975 1.0 0.5765732541071299 13 Q9NY93,Q96EB6,Q92499,P30511,Q7Z434,Q9NR30 6 +T cell activation involved in immune response 0.5888504180896633 1.380133553599744 0.1675455279235285 1.0 0.5771397657841504 7 P42345,P62753 2 +Negative regulation of interleukin 2 production 0.828280044101432 1.3781736436173753 0.1681496826237061 1.0 0.5782539287549603 2 P15311 1 +Activation of protein kinase activity 0.4380242512286549 1.377167048492991 0.1684606069767369 1.0 0.5784971977726915 18 Q9UER7,P42345,Q8WXW3,Q99627,Q9ULW0,Q9H2P0,Q05655 7 +Postreplication repair 0.4981061313248134 1.3742668707384074 0.1693588473353986 1.0 0.5794292431198006 12 Q9C0J8,P61088 2 +Protein localization to presynapse 0.8601204882207287 1.3720329903081383 0.1700531680101296 1.0 0.5803761297558828 3 P33176 1 +Axo dendritic protein transport 0.8601204882207287 1.3720329903081383 0.1700531680101296 1.0 0.5803761297558828 3 P33176 1 +Response to axon injury 0.4669303456458626 1.368640762508523 0.1711115955612554 1.0 0.582606333961619 14 P10586,P21333,P00374,P11047 4 +Positive regulation of response to external stimulus 0.3098817247791471 1.367338558537586 0.1715192110593708 1.0 0.582606333961619 70 Q96ST3,Q9BY67,Q96PK6,P26583,Q9NWH9,Q7Z434,Q8WXF1,P43243,O95747,O75179,P30511,Q15648,P78536,P39019,O60828,P21333,Q9NZI8,Q15233 18 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.5065594445071122 1.3634922159022316 0.1727274360374433 1.0 0.582606333961619 11 P62081,P61254 2 +Semi lunar valve development 0.7299471208280068 1.363300145927765 0.1727879360656696 1.0 0.582606333961619 4 Q13464,Q04721 2 +Potassium ion import across plasma membrane 0.6227977094623842 1.362735783849953 0.172965795883526 1.0 0.582606333961619 6 P05026 1 +Positive regulation of transcription by rna polymerase ii 0.3656822071190126 1.3624594399220054 0.1730529361196011 1.0 0.582606333961619 179 Q96ST3,Q9NQG5,Q15014,Q8WWK9,Q9NWH9,O60885,Q13573,P13984,P51608,P38159,O95747,Q92922,Q92785,Q15648,Q92974,P51858,Q9P2D1,Q7Z3K3,Q96T23,P82094,Q8WUB8,Q9Y2W1,Q13526,Q12830,O14974,Q9NXV6,P53999,P25490,P06748,P23246,Q96T37,Q7L2J0,O14776,Q9Y467,P17096,P19338,Q9UM54,Q01664,Q9H1B7,Q99459,Q96EB6,Q9HCK8,Q7Z434,Q9NYF8,Q96I24,O94776,Q8IVW6,Q96PK6,P26583,P09874,P18615,P51610,P17980,Q8NCF5,Q9H1E3,Q9H7B4 56 +Regulation of histone h3 k9 trimethylation 0.6771262795467847 1.361850232859113 0.1732451548560871 1.0 0.582606333961619 5 P02545,P51608,Q96EB6 3 +Regulation of dna repair 0.3265670368776593 1.3618334878999885 0.1732504405255641 1.0 0.582606333961619 54 P16104,Q7Z3K3,Q15014,Q9HAF1,P09874,Q9NPF5,Q7Z4V5,Q9UNS1,P18887,P61088,Q9NYB0,Q96T60,Q15906 13 +Regulation of cell cell adhesion mediated by cadherin 0.6767543018069602 1.360170525376102 0.1737759674675394 1.0 0.5829282453518367 5 Q07157,P55196,P49593 3 +Regulation of viral entry into host cell 0.6221184222406447 1.359441210043269 0.1740068199404412 1.0 0.5830840154829773 6 O60493,P19474,P14373,P07237 4 +Negative regulation of vasculature development 0.4454018492959593 1.3591904029684911 0.1740862616020364 1.0 0.5830840154829773 16 Q13464,Q4VCS5,P51608,P55011 4 +Mesenchyme development 0.3475241899797745 1.3589182364956975 0.1741724993712285 1.0 0.5830840154829773 41 Q13464,Q15910,Q13428,P42345,Q13308,O95747,P80723,P19022,Q14978,P21333 10 +Snrna modification 0.6762201012129083 1.3577582150282324 0.174540417750209 1.0 0.5840222315680023 5 Q9NPE3,Q7L2J0 2 +Cellular response to ketone 0.4035968082256806 1.3559007512382533 0.1751307484733513 1.0 0.5851158707770644 23 Q01664,Q6PKG0,Q96EB6,Q13185,P20020,O75116,Q9H7B4,P11802,P40818 9 +Myoblast migration 0.8227673649393834 1.3547391144471226 0.1755006911074359 1.0 0.5857643307404602 2 Q13464 1 +Positive regulation of fatty acid biosynthetic process 0.822767364939359 1.3547391144470189 0.175500691107469 1.0 0.5857643307404602 2 Q92604 1 +Protein kinase b signaling 0.3706505446365017 1.35340785933076 0.1759253680215264 1.0 0.5859804803172081 27 Q8NC56,Q9NWH9,P42345,Q9NZM5,Q96EB6,O00165,O00291,O14745 8 +Rig i signaling pathway 0.5046503557375314 1.351725287927936 0.1764632123017453 1.0 0.5859804803172081 11 O75179,Q9NZM5,Q9H078 3 +Positive regulation of transcription by rna polymerase iii 0.5293936126285363 1.3464730134605436 0.1781500178724864 1.0 0.5859804803172081 9 Q9NY93,O60264,P42345,Q9HCK8,Q9NR30,Q9UIG0 6 +Negative regulation of smooth muscle cell differentiation 0.7258687258687126 1.3460172942246498 0.1782969392440554 1.0 0.5859804803172081 4 P26358,O75179,P51608 3 +Regulation of chromosome organization 0.3106716425099343 1.3456961290721776 0.1784005352722504 1.0 0.5859804803172081 102 Q96ST3,O60832,Q13123,P18887,Q15398,Q9UIG0,P39748,Q96QC0,P12270,O60934,Q9H981,Q9NYB0,Q92878,Q7Z7K6,P25490,P23246,Q9Y6D9,P26358,Q14980,P49750,Q9Y6A5,Q96T60,P09874,O95347 24 +Dicarboxylic acid metabolic process 0.342820545751947 1.3455144191232196 0.1784591680331679 1.0 0.5859804803172081 43 O75874,P00374,P48735 3 +Tetrahydrofolate interconversion 0.6187278724725168 1.3429942001329545 0.1792738518751915 1.0 0.5859804803172081 6 Q6UB35,P11586,P13995 3 +Positive regulation of protein autophosphorylation 0.5814531904937701 1.341831296289427 0.1796507022288267 1.0 0.586590629836868 7 Q92878 1 +Glutamine family amino acid metabolic process 0.3671979739508164 1.341104214549717 0.179886619146911 1.0 0.586590629836868 29 Q05682,Q9ULX3 2 +Aorta morphogenesis 0.8518428559091056 1.3398175094689575 0.1803046817000106 1.0 0.5873788701640446 3 Q96AY3 1 +Synaptic vesicle endosomal processing 0.6718932019066004 1.3382165037870792 0.1808258706906738 1.0 0.5881356927724622 5 Q9NZM3,Q15075 2 +Late endosome to vacuole transport via multivesicular body sorting pathway 0.5279368394331241 1.3380694405451146 0.1808738014786315 1.0 0.5881356927724622 9 Q9NP79,Q9H444 2 +Sister chromatid cohesion 0.3689888689945131 1.3373100449406627 0.181121453495245 1.0 0.5881356927724622 27 Q7Z3K3,P23246,Q9UQE7,Q12834,P39748,Q14683 6 +Negative regulation of mrna 3 end processing 0.5804942429014228 1.336864411364854 0.1812668994483766 1.0 0.5881356927724622 7 Q6PJT7,P18615,O75150,O00267 4 +Regulation of response to extracellular stimulus 0.6170422992940316 1.334816285746535 0.1819364819507694 1.0 0.5881356927724622 6 Q13573 1 +Positive regulation of biomineralization 0.7228350799779246 1.3331602921675436 0.1824792069889942 1.0 0.5881356927724622 4 O95747,P20020,P04920 3 +Mitochondrial dna metabolic process 0.6165483365114948 1.3324195602798763 0.1827223580514023 1.0 0.5881733553323664 6 P49916,P09874,Q14249 3 +Cell proliferation in forebrain 0.7222835079977808 1.3308225656070038 0.1832474010778568 1.0 0.5881733553323664 4 Q86VS8,Q96N67,Q9NZI8 3 +Regulation of mitotic cell cycle spindle assembly checkpoint 0.6161953606067364 1.330706866811994 0.1832854826883807 1.0 0.5881733553323664 6 Q9Y6G9,Q96SN8,P12270,Q9Y6D9 4 +Cellular component morphogenesis 0.3495194077275805 1.329884592307701 0.1835562986796186 1.0 0.5887588164677994 153 Q96ST3,Q9Y281,Q13464,P46821,Q8IZP0,Q9BVA1,Q9Y2J2,O60271,Q9NZM3,Q9Y4W6,Q7Z406,P83731,Q96N67,P46940,Q96Q89,Q6SZW1,Q9NZI8,Q96HC4,Q9UNF0,O75955,P18206,Q13177,Q13740,Q12802,O75147,P82094,P33176,Q66K74,Q9ULV4,Q04721,Q14444,P16949,Q9GZT3,O75592,Q9UJU6,P19022,Q9UNW9,P50570,Q9Y639,Q8WX93,P48681,P07900,Q14247,P26367,P84095,Q7Z460,Q8TB37,Q9BPU6,P11047,Q9Y6W5,Q8N8S7,Q9NYL9,Q16527,P08238,Q9H2P0,Q15149,Q9GZY8,Q04837,P51956,Q9ULH0,Q9UQ16,Q9BRT6,Q14315,Q13596,P53990,Q9UQB8,O60828,Q8N3R9 68 +Metanephros development 0.5263795655731112 1.3290854541551476 0.1838197786343403 1.0 0.5890367317277417 9 O95747,P11047 2 +Pyrimidine nucleobase biosynthetic process 0.5785310359717876 1.3266951465183094 0.1846095471301123 1.0 0.5907150830839618 7 Q05682 1 +Response to transforming growth factor beta 0.3475361727357554 1.3254902750746704 0.1850085928150315 1.0 0.5908567810804124 39 Q13177,P62942,Q13464,P09874,Q13526,Q13573,Q9Y4E8,Q9Y2U8,Q15942,Q96EB6,P08238,O75116,P78536,O14737,Q8N3R9 15 +Photoreceptor cell maintenance 0.6687971422173702 1.3242314775263735 0.1854261797474516 1.0 0.591623184615672 5 Q15051,P11166 2 +Retina homeostasis 0.6687971422173702 1.3242314775263735 0.1854261797474516 1.0 0.591623184615672 5 Q15051,P11166 2 +Positive regulation of keratinocyte differentiation 0.6672750610486977 1.317355718050674 0.1877194167473765 1.0 0.5958514519422078 5 Q14980,Q15648 2 +Regulation of protein containing complex disassembly 0.3295406623478587 1.3169951898083212 0.1878402369315348 1.0 0.5958514519422078 48 Q9Y281,P46821,O95104,Q8WWK9,Q01082,Q9Y3E1,Q96GD0,Q9UHB6,P35611,Q13813,Q9NYL9,Q9ULW0,Q92974,P47755,P48681 15 +Negative regulation of epithelial cell proliferation 0.4395942489283747 1.3167747917418016 0.1879141249670637 1.0 0.5958514519422078 16 Q9UII2,Q9Y366,P52758,Q15648,P58107,Q12904 6 +Positive regulation of protein depolymerization 0.6128547568165555 1.3144962475011368 0.1886792600691822 1.0 0.5977086212938146 6 Q9Y281,P48681 2 +Interferon gamma mediated signaling pathway 0.6664297806671438 1.3135372062365978 0.1890019922438384 1.0 0.5981680131118369 5 Q16543,Q15648 2 +Potassium ion homeostasis 0.6663769971002812 1.3132987573361423 0.1890822971153212 1.0 0.5981680131118369 5 P05026 1 +Positive regulation of histone deacetylation 0.5387418083461772 1.3122349572392848 0.1894408703944679 1.0 0.5982841152664086 8 Q13363,Q9UHR5,Q96EB6 3 +Cellular anion homeostasis 0.8445805972649179 1.3115630111130818 0.1896676202283855 1.0 0.5982841152664086 3 O14745 1 +Epithelial cell development 0.3290962796404012 1.311558402400636 0.189669176139696 1.0 0.5982841152664086 48 Q13464,Q07157,Q9NWH9,Q9UDY2,Q04721,P55196,P15311,O14974,P11047,P19022,P35611,O75369,O75116,Q15149,P18206 15 +Dosage compensation 0.5073296227775008 1.311077874552665 0.1898314549986699 1.0 0.5984067640687851 10 A6NHR9,Q01780,Q96T37,Q96MU7,Q9P0M6,Q92900,O75367,Q00839 8 +Regulation of protein adp ribosylation 0.6112550628505962 1.3067327909088555 0.1913034779800262 1.0 0.5998680083759409 6 Q9H2P0,P18887 2 +Neuron projection regeneration 0.506586250928847 1.306619804933399 0.1913418669767148 1.0 0.5998680083759409 10 P21333,P00374,P11047 3 +Negative regulation of protein catabolic process 0.33545433582552 1.3059550307918764 0.1915678506145037 1.0 0.6002939890845833 45 O60493,Q13464,Q04323,Q9NZM5,Q13526,P62913,O75592,P62081,P21333 9 +Cell death in response to oxidative stress 0.364557471118173 1.3039262850557365 0.1922587171958949 1.0 0.6017574371218783 28 P23246,Q14249,Q9NWH9,P09874,Q969S3,O75915,Q9UMX0,Q15233 8 +Regulation of microtubule depolymerization 0.4573547628256067 1.3029468243658862 0.192592916439521 1.0 0.6020901029188592 14 P46821,Q66K74,Q8WWK9,Q9Y3E1,Q92974,Q9ULW0,O15344 7 +Response to temperature stimulus 0.325815708732912 1.302175771439907 0.1928563056205885 1.0 0.6024791347199077 49 Q9UER7,P0DMV9,O75475,P12270,Q16576,P42345,O75190,P54652,P31689,Q99543,P25685,Q96EB6,Q96EY1,P20020,P55072 15 +Primitive hemopoiesis 0.8103638368246953 1.3020531183339594 0.1928982279131736 1.0 0.6024791347199077 2 Q13769 1 +Clathrin coat assembly 0.5056472821353042 1.3009887148409065 0.1932623175720011 1.0 0.6033334393930047 10 P09496,O75146 2 +Ribosomal small subunit assembly 0.4406727100518459 1.296392163829953 0.1948404104286774 1.0 0.6057609952376979 15 P46782,P62263,P82912,P62841,P62857,P39019 6 +Regulation of striated muscle cell differentiation 0.4404273298975447 1.2946359427380154 0.1954458471652562 1.0 0.6064248186278108 15 P42345,Q13049,Q15014,Q15910 4 +Regulation of myeloid cell differentiation 0.3564808056879798 1.293548204208579 0.1958215233680627 1.0 0.6067734831060622 33 P0DMV9,Q8IYB5,Q96T37,P26583,Q9UKV3,P42345,Q6P1J9,Q04721,O15347,Q15648,O95628,O00165,P62805 13 +Regulation of protein polymerization 0.3092220180010558 1.2917350245384167 0.1964489237311839 1.0 0.6078693589861345 67 P46821,Q96SN8,Q9NWH9,P51608,P35611,P62993,P35241,P16949,Q9UJU6,O75146,Q13813,Q14008,P07900,O00165,Q14247,P59998,P0DMV9,Q14203,Q7Z460,Q9P270,Q14980,Q9NYL9,Q01082,P42345,Q16625,P47755,Q9UQB8,Q05655 28 +Megakaryocyte development 0.7113657704182301 1.284549543276433 0.1989497402665687 1.0 0.6147510063338966 4 Q8IZP0,Q15648 2 +Regulation of rig i signaling pathway 0.5702223824666937 1.28365002542867 0.199264437633214 1.0 0.6152333829070369 7 Q9NZM5 1 +Utp metabolic process 0.60648373987404 1.2835754352062982 0.1992905494316099 1.0 0.6152333829070369 6 Q05682,P27144 2 +Glutamine metabolic process 0.4692459781609109 1.2818402268079765 0.1998986995993763 1.0 0.6158341610274543 13 Q05682 1 +Regulation of dendrite extension 0.8367100574465562 1.2809582443415095 0.2002083329458666 1.0 0.6158341610274543 3 Q9NZM3 1 +Development of secondary sexual characteristics 0.7103711109620158 1.2803342525625674 0.2004276061466294 1.0 0.6158341610274543 4 Q15648 1 +Cell cycle dna replication initiation 0.6057363156935596 1.2799477540903494 0.2005635111411998 1.0 0.6158341610274543 6 P33991,P25205 2 +Negative regulation of respiratory burst 0.8048511576626252 1.2786628322837237 0.2010158134672406 1.0 0.6162758165295706 2 P39019 1 +Establishment or maintenance of cytoskeleton polarity 0.6586245026273733 1.2782766132280272 0.2011519108862565 1.0 0.6164093975732479 5 P02545,Q14008,Q99661 3 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.6580754552968273 1.2757963867058355 0.2020275052008746 1.0 0.6178764757618715 5 Q9Y6D9 1 +Kidney mesenchyme development 0.8353556070783705 1.27569365006111 0.20206383414703 1.0 0.6178764757618715 3 O95747 1 +Metanephric mesenchyme development 0.8353556070783705 1.27569365006111 0.20206383414703 1.0 0.6178764757618715 3 O95747 1 +Regulation of kidney development 0.8353556070783705 1.27569365006111 0.20206383414703 1.0 0.6178764757618715 3 O95747 1 +Endothelial cell apoptotic process 0.7089800914320936 1.2744394701621171 0.2025077115891369 1.0 0.6182888976199955 4 O96013,Q53EL6 2 +Myeloid cell homeostasis 0.3326664714626285 1.2731459875380553 0.2029662427724547 1.0 0.6190998082396594 45 Q9UII2,P0DMV9,P39019,P04083,P62263,P26583,Q9UKV3,Q99496,Q9NYL9,Q15648,P78536,Q9H9B4,Q9GZZ9,P62753 14 +Regulation of protein localization to endosome 0.7084942084942059 1.2723805011142235 0.2032379586640851 1.0 0.6190998082396594 4 O75116,P26038,P15311 3 +Positive regulation of protein localization to early endosome 0.7084942084942059 1.2723805011142235 0.2032379586640851 1.0 0.6190998082396594 4 O75116,P26038,P15311 3 +Regulation of protein deubiquitination 0.5679811679550717 1.272038527481013 0.2033594306617652 1.0 0.6191867125542413 7 Q04323,Q9NZM5,P55072 3 +Regulation of hydrogen peroxide mediated programmed cell death 0.6562229860664319 1.2674284579981914 0.2050021295410005 1.0 0.6216010260993191 5 Q14249,Q9NWH9 2 +Programmed cell death in response to reactive oxygen species 0.6562229860664319 1.2674284579981914 0.2050021295410005 1.0 0.6216010260993191 5 Q14249,Q9NWH9 2 +Artery development 0.4995905133750654 1.2646682935715223 0.2059902603884162 1.0 0.6222476464927486 10 Q96AY3 1 +Dorsal ventral pattern formation 0.6025692249065201 1.2645762362113186 0.2060232761732163 1.0 0.6222476464927486 6 Q9Y366 1 +Protein adp ribosylation 0.4808218626176669 1.2645730841747689 0.2060244066990675 1.0 0.6222476464927486 12 P09874,P18887,Q9H2P0,Q9ULX3,Q96T60 5 +Cleavage involved in rrna processing 0.3929523718375386 1.2642966344842343 0.2061235771152527 1.0 0.6222476464927486 23 Q14137,Q15050,P78316,Q14692,Q8N9T8,Q2NL82,Q9ULX3,Q86U38 8 +Proximal distal pattern formation 0.8321201381241075 1.2631208555110458 0.2065457500163967 1.0 0.6222476464927486 3 O95747 1 +Cellular amino acid biosynthetic process 0.3516788518189387 1.262688198306566 0.2067012569731914 1.0 0.6222520442636246 34 P00374 1 +Negative regulation of cellular catabolic process 0.2988043416610434 1.2620961267259994 0.2069141988417144 1.0 0.6225925169964582 95 Q13464,Q9H444,P11940,Q9NWH9,Q04323,Q6PKG0,Q9NZM5,Q9Y2W1,P42345,Q13151,P62913,Q9H7Z3,P98175,P62081,Q9H814,P46777,Q08379 17 +Regulation of response to wounding 0.3995012381646637 1.2618541730407244 0.2070012646573333 1.0 0.6225925169964582 22 P80404,P04083,Q7Z460,P42345,P55011,Q16625,P10586,Q4KMQ2,P58107,P21333,Q05655 11 +Negative regulation of canonical wnt signaling pathway 0.4057899129123795 1.2607991449725326 0.207381221948554 1.0 0.6230011908123554 21 P19022,Q13283,Q8NBM4,Q9HCK8 4 +Artery morphogenesis 0.6015119132118854 1.2594447381163771 0.2078697387825387 1.0 0.6233310487528058 6 Q96AY3 1 +Regulation of myeloid leukocyte mediated immunity 0.465708838356762 1.2585345883622996 0.2081984863987407 1.0 0.6233310487528058 13 Q12846,P11274,Q9NY93,Q92499,Q7Z434,Q9NR30,P51809 7 +Smad protein signal transduction 0.5139204275415141 1.257203257439778 0.2086800440666323 1.0 0.6233310487528058 9 P53999,Q96PK6,P09874,Q6PIU2 4 +Anatomical structure homeostasis 0.3368020967346828 1.2563948114174917 0.2089728618953517 1.0 0.6233310487528058 42 Q9Y281,Q14203,Q07157,Q9H444,Q9UQN3,Q15051,P11166,Q9UDY2,P55011,Q16625,P11047,Q13049,P18206 13 +Negative regulation of wound healing 0.5136481594050639 1.255632709701139 0.2092491663656044 1.0 0.6233310487528058 9 P80404,Q7Z460,P55011,P58107,Q05655 5 +Regulation of blood brain barrier permeability 0.8301626688723451 1.2555165732455436 0.2092912955471373 1.0 0.6233310487528058 3 Q07157,Q9UDY2 2 +Positive regulation of blood brain barrier permeability 0.8301626688723451 1.2555165732455436 0.2092912955471373 1.0 0.6233310487528058 3 Q07157,Q9UDY2 2 +Positive regulation of vascular permeability 0.8301626688723451 1.2555165732455436 0.2092912955471373 1.0 0.6233310487528058 3 Q07157,Q9UDY2 2 +Sodium ion transmembrane transport 0.411113870479335 1.2554138811232654 0.2093285528355255 1.0 0.6233310487528058 20 P55011,P46939,O14745,P05026 4 +Late endosome to golgi transport 0.8300863836688126 1.255220261423552 0.2093988122348813 1.0 0.6233310487528058 3 Q8IWJ2 1 +Base excision repair gap filling 0.4976332813933931 1.2529336503385111 0.2102298542816831 1.0 0.6250397835929842 10 P49916,P39748,Q96T60 3 +Muscle hypertrophy 0.3983912554122588 1.2525590411209393 0.2103662288588268 1.0 0.6250397835929842 22 Q13464,Q12802,Q15910,P09874,P02545,O75116,Q96HC4,P25490 8 +Endosome to lysosome transport via multivesicular body sorting pathway 0.652504069722552 1.250631267278801 0.2110690375245782 1.0 0.6252452029441109 5 Q9UQN3,Q9Y3E7 2 +Adherens junction organization 0.4342158242308536 1.2501948735859725 0.2112283690392553 1.0 0.6252452029441109 15 P35611,Q07157,P18206,Q15149 4 +Rna methylation 0.3522117376582812 1.2497190382307244 0.2114022001776327 1.0 0.6252452029441109 33 Q7L2J0,Q8WVM0,Q96T37,Q8IY81,Q15007,P46087,Q9HC36,Q96FX7 8 +Embryonic hemopoiesis 0.7027749994664819 1.248148786286808 0.211976574955043 1.0 0.6252452029441109 4 Q13769,Q15648 2 +Positive regulation of myeloid leukocyte cytokine production involved in immune response 0.563276065727422 1.2476643035911137 0.2121540189424564 1.0 0.6252452029441109 7 Q7Z434,Q92499,Q9NR30,Q96EB6 4 +Negative regulation of catabolic process 0.309224123039622 1.24761405260489 0.2121724297353167 1.0 0.6252452029441109 107 Q13464,Q9NWH9,Q04323,Q6PKG0,P62913,O60493,Q9NZM5,Q9Y2W1,Q13526,O75592,P98175,Q9H814,Q9H444,Q13151,P62081,P46777,P11940,P42345,Q9H7Z3,Q08379,P21333 21 +Negative regulation of actin filament bundle assembly 0.4876505980982686 1.2469343644444395 0.2124215650765375 1.0 0.6253435556959316 11 Q13177,Q07157,Q9NWH9,P16949,Q9Y6W5,Q13136 6 +Microtubule based process 0.3761262512689928 1.2449195889623703 0.2131613095127056 1.0 0.6258618968592529 241 Q3KQU3,Q9UPN4,Q9NWH9,Q12834,Q8TD16,Q96CS2,Q92974,P82094,O14974,Q9BSJ2,P43487,Q9NQS7,P06748,Q13409,P0DMV9,P23246,Q9P270,P27816,Q14980,Q9UNZ2,Q16625,Q9Y366,O43237,P55072,Q96ED9,Q13464,Q9UQN3,P51608,Q96N67,Q9HD42,O75147,P12270,Q02241,Q9BV73,Q86VS8,Q9NZZ3,Q8IWJ2,Q9H444,Q96EB6,Q9H3R5,Q14807,Q9ULW0,Q9Y6G9,P35579,O60610,Q9Y496,O75116,Q8NCM8,P11142,P23258,P46821,Q9Y3E7,Q9Y3E1,Q9H0H5,Q7Z4H7,O15344,Q9Y448,Q86UP2,Q92572,P16949,Q9GZT3,O14745,Q96PK6,Q9H2G2,Q08379,P21333,Q14683,Q8WWK9,P18583,Q15398,P33176,Q13526,P15311,Q14008,Q14203,Q9UQE7,P02545,Q9Y6A5,Q9HC35,Q14168 80 +Negative regulation of type 2 immune response 0.7963065049614091 1.242449688168777 0.2140706924789992 1.0 0.6271499354859686 2 P04083 1 +Type 2 immune response 0.7963065049614091 1.242449688168777 0.2140706924789992 1.0 0.6271499354859686 2 P04083 1 +Actin crosslink formation 0.8263027295285349 1.2405272891633052 0.2147804270553717 1.0 0.627501390447168 3 P21333,P29966 2 +Histone h3 k9 methylation 0.4865487286906195 1.240145216036641 0.2149216872670127 1.0 0.627501390447168 11 P26358,P02545,P51608 3 +Mesenchymal to epithelial transition 0.7000209238193559 1.2364833131658843 0.2162789646362117 1.0 0.6288224450303384 4 P80723 1 +Positive regulation of dna metabolic process 0.2950958913351467 1.233927378421276 0.2172299664332884 1.0 0.6291423506082824 93 Q8WVB6,Q15014,Q14249,O60832,Q9NPF5,P51608,P18887,Q9UNS1,Q7Z3K3,Q96QC0,Q9HAF1,O60934,Q7Z4V5,P61088,Q96QE3,Q92878,P16104,Q9BRX5,Q96T60,P09874,Q15906 21 +Regulation of signal transduction by p53 class mediator 0.3391576232983017 1.233281786994686 0.2174706505513435 1.0 0.6291423506082824 39 P61254,Q9BW85,Q9NZM5,P42345,Q15050,P62913,P46087,P62841,Q96EB6,P62081,P46777,Q96QE3,O94992 13 +Endonucleolytic cleavage involved in rrna processing 0.4471425293809039 1.2329243233729728 0.2176039996747911 1.0 0.6291423506082824 14 Q14137,Q15050,P78316,Q14692,Q8N9T8,Q2NL82,Q86U38 7 +Telomere maintenance via telomere lengthening 0.3377402477860707 1.232447549799628 0.2177819479701048 1.0 0.6291628896723289 40 O60832,P49959,P22626,P27361,Q9NYB0,Q92878,P35251,P07900,Q00839,P09651,P07910,Q9NPE3,P13010,P08238,Q96T60,P50991,Q01780,P09874,P78371,P17987 20 +Plus end directed organelle transport along microtubule 0.7938257993384756 1.2319473008077908 0.217968770543941 1.0 0.6291628896723289 2 P33176 1 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.4277776155332216 1.2305372011498572 0.2184960051435653 1.0 0.6302492548724387 16 P62942,Q8NC56,Q13526,Q9UNH7,Q96EB6,Q9Y2U8,Q6YHK3,Q8N0X7,P50570,Q9UNE7,P78536,Q9UPN9,P04637 13 +Sensory system development 0.3265616419050507 1.225707108713961 0.2203089141356105 1.0 0.6315395808827182 46 Q9P2D1,O75147,Q9Y467,P11047,P20020,P83731,Q15648,O94788,Q15042,P48681,O15078,P25490 12 +Negative regulation of dna templated transcription elongation 0.4929578128575241 1.2249097955773969 0.2206092092647487 1.0 0.6321284095147337 10 Q15910,O14776 2 +Erythrocyte homeostasis 0.3394725139823719 1.2234438766404463 0.2211620897262411 1.0 0.6326242343307079 38 Q9UII2,P0DMV9,P39019,P62263,P26583,Q9UKV3,Q9NYL9,Q15648,Q9H9B4,Q9GZZ9,P62753 11 +Membrane biogenesis 0.3549202387383112 1.2201052081313772 0.2224249944922443 1.0 0.6359636537799706 29 Q12846,Q9H444,Q9UQN3,Q9Y3E7,Q9UNZ2,P19022,Q01082,Q9HD42,Q9NZZ3,Q9UN37,Q9UNF0 11 +Regulation of centriole replication 0.5929951605626436 1.2181183781581657 0.2231789909081318 1.0 0.6369295386310897 6 P06748,Q96PK6 2 +Cd4 positive alpha beta t cell activation 0.5926432919141144 1.2164114628551417 0.223828219493666 1.0 0.6374015263904776 6 P42345,P04083,P78540 3 +Tubulin deacetylation 0.5570127241458155 1.2152283885782502 0.2242789958255255 1.0 0.6379789368871269 7 P51956,P21333 2 +Regulation of nuclear division 0.3329446851849127 1.2126627978018958 0.2252587687929181 1.0 0.6397321189082991 42 O75147,P12270,P46013,Q9Y6D9,Q12834,Q96GD0,Q13526,Q99640,Q13123,Q15398 10 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4586827834136741 1.2122717296335894 0.2254083818147139 1.0 0.6397321189082991 13 Q13049,P61254 2 +Viral release from host cell 0.4110906489983247 1.211855995162266 0.2255675093538869 1.0 0.6397321189082991 19 Q9H444,Q9UQN3,Q9Y3E7,P53990,Q9HD42,Q9UN37 6 +Cardiac septum development 0.4435593872305632 1.2083810299062063 0.2269007332011514 1.0 0.6410791590504522 14 Q13308,Q9P2D1,P43243,Q96T37 4 +Microtubule based movement 0.2843108388915997 1.207710849846642 0.2271585031668599 1.0 0.6410791590504522 84 P46821,Q9UPN4,Q99661,Q8TD16,Q15398,P33176,Q66K74,P82094,Q86UP2,Q92572,Q02241,Q9GZT3,O14745,Q13409,P23246,Q14203,P27816,Q14807,Q9Y6G9,Q9Y496,Q9Y366,O43237,Q86Y91,Q14168,Q8NCM8,P11142 26 +Sensory perception 0.3250368826133867 1.2076102304052256 0.2271972222332809 1.0 0.6410791590504522 46 Q9P2D1,Q9UM54,P51608,P11047,Q9BV73,Q7Z406,Q9BRK0,Q9ULX3,O14745 9 +Negative regulation of dna replication 0.5050370152126289 1.2059801254627762 0.2278251537249001 1.0 0.6418579016912217 9 P49916,Q9UNS1 2 +Positive regulation of myeloid leukocyte differentiation 0.6923912001810459 1.204181533217393 0.2285194219363566 1.0 0.6421858198335518 4 Q04721,Q9UKV3 2 +Membrane repolarization during cardiac muscle cell action potential 0.692311507734179 1.203844284863405 0.2286497695354525 1.0 0.6421858198335518 4 P05026 1 +Membrane repolarization during action potential 0.692311507734179 1.203844284863405 0.2286497695354525 1.0 0.6421858198335518 4 P05026 1 +Interleukin 8 production 0.5190935609061869 1.2029784760483857 0.2289846498849552 1.0 0.6428553466218171 8 Q7Z434,P0DMV9 2 +Interferon beta production 0.4710494325686026 1.202604479344242 0.2291294134702386 1.0 0.6429449029392789 12 Q7Z434,P26583,O14802 3 +Negative regulation of binding 0.3319711268581498 1.2016429185593431 0.2295019055415661 1.0 0.6434939792583811 42 Q96T23,Q13464,Q7L2J0,Q01664,P30533,Q13526,P10586,Q08379,Q9H2P0,P48681 10 +Regulation of cellular response to transforming growth factor beta stimulus 0.4149467132982539 1.201315037952544 0.2296290192871586 1.0 0.6435795231346448 18 P62942,Q13526,Q13573,Q96EB6,Q9Y2U8,P78536,P08238,Q8N3R9 8 +Negative regulation of cell cycle 0.2910534810281021 1.200737543207696 0.2298530259778788 1.0 0.6436657667358675 91 Q13123,Q9UNS1,Q14676,Q9UIG0,Q9UN37,Q13564,Q96QC0,P12270,O60934,Q9NZM5,O14745,P06748,P16104,Q9Y6D9,Q15910,Q01664,P61254,Q99459,Q96EB6,P54132,Q9Y6G9,Q13769,Q96PK6 23 +Protein k48 linked deubiquitination 0.479550462707879 1.19704870524829 0.2312875714085343 1.0 0.6457828167324624 11 Q04323,P40818 2 +Myelin maintenance 0.5882256511340075 1.1949861932239032 0.2320924245295552 1.0 0.6477585807356083 6 Q9Y2J2,Q8N3R9 2 +Positive regulation of potassium ion transport 0.5025873819263885 1.1918650856630533 0.2333141502294711 1.0 0.6499661246627098 9 P21333,P05026 2 +I kappab kinase nf kappab signaling 0.3118156522246242 1.1913453807817729 0.2335180254720184 1.0 0.6499661246627098 57 Q13464,O60885,O60858,O75179,Q13049,Q9UBC1,Q9NR30,Q12802,P61088,Q8IUH4,Q9NYB0,Q6P1N0,P62942,Q9NY93,Q96EB6,O60826,Q7Z434,P14373,Q92499,O75116,P21333 21 +Microtubule bundle formation 0.4223475469272678 1.1909737374697953 0.2336638950115865 1.0 0.6499661246627098 16 Q9UPN4 1 +Spliceosomal conformational changes to generate catalytic conformation 0.6885008563426294 1.1877221922341106 0.2349428775624482 1.0 0.6521675983221812 4 Q9ULR0 1 +Regulation of sodium ion transport 0.4177118976078715 1.1870979146533327 0.2351890008174257 1.0 0.6521675983221812 17 P46939,O14745,P05026 3 +Positive regulation of nuclear cell cycle dna replication 0.8123696460760219 1.1864967536394089 0.2354261827526986 1.0 0.6521675983221812 3 O00311 1 +Negative regulation of biosynthetic process 0.3558573578286967 1.186111892595022 0.2355781145961311 1.0 0.6521675983221812 337 Q96ST3,Q9UPT8,Q6PKG0,P00374,Q96KM6,Q92541,Q9NZI8,Q9NP66,Q15233,Q9NZM5,Q9BQ70,Q12906,P25685,Q8IZD4,P98175,Q9Y2K7,O95104,P25490,Q7L2J0,P23246,Q96T37,O14776,Q9UKZ1,Q9H1B7,Q96EY1,Q9HCK8,P54132,Q9NYF8,Q96L73,P82979,Q01130,P14373,P40429,Q15906,Q13464,Q13573,P51608,Q9HCD5,Q99543,Q86YP4,Q15637,Q8TDD1,Q5VUA4,Q9UER7,Q8IX12,P12270,O75175,O75446,P16402,Q04721,Q14444,Q8WXI9,Q13043,Q15910,P16383,P17096,P19338,P26358,Q96EB6,O94776,P11940,P26583,P62263,P18615,Q9NS86,O75116,O94992,P11142,P45973,Q9NPF5,Q92785,Q15648,P51858,O95983,Q71SY5,Q8N6R0,Q969G3,Q12830,Q6IAN0,P16403,P10412,Q8WXF1,Q13185,O75190,P21333,Q9Y6M1,O95747,Q9UNS1,Q92945,Q96T23,Q8WUB8,P15311,P80723,Q6P1N0,Q01664,Q99496,Q13416,P09874,P49916,P51610,Q9UHI6,Q9P0M6 102 +Camera type eye development 0.3321269978351798 1.1859803683513035 0.2356300524109111 1.0 0.6521675983221812 41 Q9P2D1,O75147,P11047,P20020,P83731,Q15648,O94788,Q15042,P48681,O15078,P25490 11 +Pallium development 0.3250656238623358 1.183973903385567 0.2364233933285946 1.0 0.6538201105666656 45 P16104,Q15910,P11166,P19022,P18887,Q9Y6A5,Q8N3R9,P07942 8 +Formation of primary germ layer 0.4073555676562267 1.1827974935388783 0.2368894141860509 1.0 0.6540139810299102 19 Q92541 1 +Cilium organization 0.2972914114703945 1.1823989754169837 0.2370474295597779 1.0 0.6540139810299102 70 Q9UPN4,Q9UHD8,O15078,Q14141,Q9BV73,Q15555,O14745,Q14203,P27816,Q9H4M9,Q9NT62,Q9Y5K8,O95721,Q15019,Q4KMP7,Q15051,Q9H223,Q9Y496,Q9Y366,P21333,Q8NCM8 21 +Rrna transcription 0.3899246391481362 1.181764431346379 0.2372991846672449 1.0 0.6540139810299102 22 Q13428,P42345,Q9NZM5,P19338,Q9Y5Q8 5 +Dendrite extension 0.5852566696349382 1.1805926674976606 0.2377645779152031 1.0 0.6540139810299102 6 Q9NZM3,Q9BRT6 2 +Dendritic transport 0.6367296159786964 1.1794369372815685 0.2382242341282743 1.0 0.6540139810299102 5 P23246,P33176 2 +Regulation of viral process 0.3158412530997314 1.1789531855691486 0.2384168176500418 1.0 0.6540139810299102 49 O60493,Q96T23,P11940,Q16513,Q7Z434,O60858,Q6PKG0,O95793,Q12906,Q13049,Q9UN37 11 +Nuclear export 0.2915918247656279 1.177228481598094 0.2391043235375147 1.0 0.6540139810299102 93 O75152,P12270,P82979,Q6P6C2,Q9NPA8,Q9BY77,Q96GA3,Q9H814,Q9NVU7,P49790,Q86V81,P35658 12 +Negative regulation of chromosome organization 0.3337230502484044 1.17370213743605 0.2405143538245702 1.0 0.6542697530336001 39 P12270,Q9Y6D9,P09874,O60934,Q13123,P18887,Q9NYB0,Q92878,Q9UIG0 9 +Positive regulation of i kappab kinase nf kappab signaling 0.3291828073800579 1.1701259910953798 0.2419502703496752 1.0 0.6573705958684894 42 P62942,Q12802,Q9NY93,Q7Z434,O60885,O60858,P21333,P14373,O60826,O75179,Q92499,Q6P1N0,P61088,Q13049,Q8IUH4,Q9NYB0,Q9NR30 17 +Regulation of ribosome biogenesis 0.7789415656008895 1.169062970793988 0.2423782614989553 1.0 0.6577060132279453 2 Q5T3I0 1 +Purine nucleoside diphosphate catabolic process 0.7789415656008791 1.169062970793945 0.2423782614989726 1.0 0.6577060132279453 2 Q9BW91 1 +Snrna transcription by rna polymerase ii 0.8076814145487948 1.168348862229858 0.2426660733284733 1.0 0.6577060132279453 3 Q7L2J0 1 +Regulation of snrna transcription by rna polymerase ii 0.8076814145487948 1.168348862229858 0.2426660733284733 1.0 0.6577060132279453 3 Q7L2J0 1 +Snrna transcription 0.8076814145487948 1.168348862229858 0.2426660733284733 1.0 0.6577060132279453 3 Q7L2J0 1 +Folic acid containing compound metabolic process 0.4519241035843651 1.1678293253068288 0.24287561664263 1.0 0.6580062456580729 13 P00374 1 +Regulation of transcription elongation from rna polymerase ii promoter 0.4148074843659539 1.165521598719038 0.2438079226253469 1.0 0.6594110730505353 17 Q15910,O14776,O60885,Q9Y5B9,Q6P1J9,P18615,P35269,O94992 8 +Protein methylation 0.3027717622165851 1.1648774914677484 0.2440685857634517 1.0 0.6594110730505353 65 P16403,P10412,Q15910,P16402,O60885,P26358,Q13573,P51608,Q15291,P18615,P51610,Q96EB6,P02545,Q9H7B4,Q92541,Q96L73 16 +Circadian rhythm 0.3193019400321076 1.1648358633644744 0.244085438930703 1.0 0.6594110730505353 47 Q96ST3,P23246,Q15910,P42345,P11387,Q9Y2W1,Q8WXF1,O75592,Q96EB6,Q7Z6Z7,Q9UNS1,Q9Y2K7,Q15233 13 +Negative regulation of protein kinase b signaling 0.547072619594773 1.1637982283395365 0.2445057903019933 1.0 0.6594110730505353 7 Q9NZM5,O14745,Q96EB6 3 +Cell cell adhesion mediated by cadherin 0.5469595458884343 1.16321363999621 0.244742833770533 1.0 0.6594110730505353 7 P19022,Q07157,P55196,P49593 4 +Uv protection 0.6823532799763893 1.1617323597707612 0.2453441968945582 1.0 0.6594110730505353 4 Q9BRK5,P39748 2 +Negative regulation of ubiquitin dependent protein catabolic process 0.3587971695950674 1.1600807854843858 0.2460159164173916 1.0 0.6594110730505353 26 Q04323,Q9NZM5,P62081,P62913 4 +Regulation of lymphocyte chemotaxis 0.8053231076992718 1.1592272207405974 0.2463635786284572 1.0 0.6594110730505353 3 P78536 1 +Regulation of t cell chemotaxis 0.8053231076992718 1.1592272207405974 0.2463635786284572 1.0 0.6594110730505353 3 P78536 1 +Positive regulation of lymphocyte chemotaxis 0.8053231076992718 1.1592272207405974 0.2463635786284572 1.0 0.6594110730505353 3 P78536 1 +Skeletal muscle cell differentiation 0.4963884721557461 1.1561743070777768 0.2476098668162891 1.0 0.6616112471357886 9 Q9Y5Q8,Q8NC56,O75446 3 +3 utr mediated mrna stabilization 0.5452415263741733 1.1543330476037224 0.2483636526430943 1.0 0.6626156916475833 7 P98175 1 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.5794513579596942 1.152466111093612 0.2491295878172368 1.0 0.6638805256153727 6 Q96QE3,P61254 2 +Positive regulation of ossification 0.6302109537100933 1.1500587018687916 0.2501196944027277 1.0 0.6646579194698733 5 O95747,P20020 2 +Spliceosomal snrnp assembly 0.3727056229301677 1.1497771776020114 0.2502356574594071 1.0 0.6646884239683085 24 O95400,O43395,Q9UHI6,P62314,O43290 5 +Protein localization to early endosome 0.5786190787273751 1.1484359457783715 0.250788641680794 1.0 0.6651090489161824 6 O75116,P26038,P15311 3 +Single strand break repair 0.8023159636062847 1.147603502445396 0.2511322832499716 1.0 0.6657553804263076 3 P09874,P18887 2 +Regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4618875928694894 1.1446134530892196 0.2523693169508831 1.0 0.6682370387626326 12 P23246,P09874,Q9UMX0,Q15233 4 +Negative regulation of establishment of protein localization to mitochondrion 0.6780921218177722 1.1437341625554984 0.2527339010234775 1.0 0.6686708691892005 4 P49257 1 +Negative regulation of sodium ion transport 0.8006609032963643 1.141209871437829 0.2537825974050101 1.0 0.6693881992176489 3 O14745 1 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.4018902130973379 1.1403549775332111 0.2541384418772261 1.0 0.6694303046282787 19 Q13573,P62081,P61254 3 +Regulation of ras protein signal transduction 0.3414945751717783 1.1401047976807657 0.2542426433870446 1.0 0.6694303046282787 33 Q12802,P11274,Q9NWH9,P46108,Q04721,P16949,Q5VZ89,Q15555,P50570,Q92974,Q8N6T3,O75955 12 +Embryonic cleavage 0.6278846762908107 1.139583034642293 0.2544600566781971 1.0 0.6695153623973734 5 Q9NY61,P11387 2 +Focal adhesion assembly 0.3641727871069858 1.1386616443294542 0.2548443063562835 1.0 0.6699971463873563 25 Q13464,P60903,P18206,P11274,Q7Z460,Q9ULV4,Q9H2G2,O75116,Q14247,P12814,P49593 11 +Positive regulation of protein maturation 0.6274768240109666 1.1377469042072694 0.2552261816801957 1.0 0.6703140459297332 5 P35579,P60903,P06733 3 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.5071885221503756 1.1369013594858046 0.2555795237507481 1.0 0.6703140459297332 8 Q9NZM5 1 +Negative regulation of wnt signaling pathway 0.3639349741204515 1.136512673803874 0.2557420644178818 1.0 0.6703140459297332 25 P19022,Q13283,Q8NBM4,Q9HCK8 4 +Smad protein complex assembly 0.7709481808158734 1.135402271029532 0.2562068085780371 1.0 0.6703140459297332 2 P09874 1 +Golgi localization 0.5758939770242094 1.1352445401801825 0.2562728722580352 1.0 0.6703140459297332 6 Q86VS8 1 +Nuclear pore complex assembly 0.4926613180605949 1.1347387646735063 0.2564847900727418 1.0 0.6703368663533197 9 P12270,P49790 2 +Eosinophil activation 0.7706725468577695 1.1342431564092532 0.2566925658710033 1.0 0.6703368663533197 2 P51809 1 +Eosinophil mediated immunity 0.7706725468577695 1.1342431564092532 0.2566925658710033 1.0 0.6703368663533197 2 P51809 1 +Negative regulation of organelle assembly 0.4776305208291822 1.1331890939626 0.2571348530993687 1.0 0.6707252902693791 10 P27816,Q9H444 2 +Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.7984803941966454 1.132790683516698 0.2573021647676534 1.0 0.6708990300125665 3 P62081 1 +Hemostasis 0.345911047250083 1.131725975525092 0.2577496573906042 1.0 0.671277645635733 29 P18206,P49257,Q13572,P21333,P35579,Q9Y490 6 +Inorganic ion import across plasma membrane 0.4920684850805229 1.1313312069691042 0.257915714179517 1.0 0.6713211404855023 9 P05026 1 +Sodium ion homeostasis 0.5407129568808131 1.130939561179893 0.2580805306991489 1.0 0.6713211404855023 7 P05026 1 +Muscle cell cellular homeostasis 0.540571580027401 1.130209627060886 0.2583879041557289 1.0 0.6714723233407336 7 Q13049 1 +Intermediate filament bundle assembly 0.7977862861879652 1.1301117102824012 0.2584291559660223 1.0 0.6714723233407336 3 P07197 1 +Positive regulation of epithelial cell differentiation 0.5057224502971938 1.1287760737498878 0.2589923083049719 1.0 0.6724697935839895 8 Q14980,Q15648 2 +Regulation of myosin light chain phosphatase activity 0.6744785034691714 1.1284832778015583 0.2591158751321076 1.0 0.6724697935839895 4 O14974 1 +Positive regulation of hydrogen peroxide mediated programmed cell death 0.7684674751929406 1.1249743301492126 0.2605999121144489 1.0 0.6747431722927456 2 Q14249 1 +Protein localization to endoplasmic reticulum exit site 0.6735887552082329 1.1247300663005957 0.2607034369356102 1.0 0.6747431722927456 4 O15027 1 +Phosphatidylinositol acyl chain remodeling 0.7681918412348396 1.1238162466888275 0.2610909876755516 1.0 0.6752283229404211 2 Q92604 1 +Auditory receptor cell morphogenesis 0.6726471359415873 1.1207588959406487 0.2623905048932262 1.0 0.6780626623734186 4 O14745 1 +Vesicle cytoskeletal trafficking 0.4124212594901504 1.1188346534863989 0.2632106849660984 1.0 0.6791284210860372 16 Q9UM54,O94832,Q9Y496,O00159,P33176,O43795 6 +Cerebral cortex development 0.3407533493290093 1.1172557020648664 0.2638850101154344 1.0 0.6800781189125819 32 P16104,P11166,P19022,Q8N3R9,P07942 5 +Protein localization to perinuclear region of cytoplasm 0.7942805166197726 1.1165889785810628 0.264170106207257 1.0 0.680286527851854 3 Q86VS8 1 +Establishment of protein localization to chromosome 0.4147654782381657 1.1114468847184529 0.2663760408639444 1.0 0.6844050651374999 15 P50991,O60832,Q9UFC0,Q9P0M6,P78371,O75367,P17987 7 +Positive regulation of protein containing complex assembly 0.3056840285009896 1.111402621012212 0.266395084657022 1.0 0.6844050651374999 57 P0DMV9,Q14203,Q9NWH9,Q9P270,P42345,Q14980,P51608,Q16625,O75146,Q13112,P55072,Q14008,Q14247 13 +Positive regulation of kinase activity 0.2893070914239684 1.111185403427307 0.2664885528319836 1.0 0.6844050651374999 72 Q8IZP0,Q9NWH9,P46940,Q99627,Q13177,Q9UER7,Q12802,O60934,Q13043,Q92878,Q9NQS7,Q15910,P30040,Q96EB6,Q9ULW0,P08238,Q9H2P0,Q13432,P42345,Q969S3,P78536 21 +Regulation of dna binding 0.3437842936943779 1.1109387331669691 0.2665947217778779 1.0 0.6844138868918006 29 Q96T23,P07305,Q01664,P26583,P09874,O60869,Q96L73 7 +Cell junction assembly 0.277206232412407 1.1094175857458448 0.2672500794220669 1.0 0.6851326206576978 83 P46821,Q13464,Q16513,Q9Y2J2,P51608,P35221,Q96HC4,O00192,O75955,P18206,Q13177,P49593,O75147,Q07157,Q9ULV4,Q9UJU6,P19022,Q9Y639,Q14247,Q9Y490,P11274,O43815,Q7Z460,P11047,Q9H2P0,O00159,Q15149,P60903,Q16625,P55196,Q9UQ16,Q9H2G2,O75116,Q13112 34 +Axis elongation 0.7921752074551092 1.1084749759964485 0.2676567404919812 1.0 0.6858189250606072 3 Q13308 1 +Negative regulation of transforming growth factor beta production 0.7643329658214164 1.1076156685133356 0.2680278336938158 1.0 0.6862419016403538 2 Q9Y5K6 1 +Negative regulation of signal transduction by p53 class mediator 0.4877017828798322 1.1062501275930496 0.2686182715272087 1.0 0.6868968514983408 9 Q9NZM5,Q96QE3,Q96EB6 3 +Protein localization to nuclear body 0.4646424839209372 1.1054632868347534 0.268958894090737 1.0 0.6869607321156125 11 P50991,Q7L2J0,O60832,P78371,P17987 5 +Negative regulation of neuron apoptotic process 0.3449423618675325 1.1052981857669788 0.2690304037961022 1.0 0.6869607321156125 27 Q13464,P51608,P51858,P48681,Q9Y4L1 5 +Sensory organ morphogenesis 0.338013870388564 1.1046804862714308 0.2692980617892437 1.0 0.6872353701731562 33 O14745,Q9P2D1,O75147,Q9UM54,Q13308,Q04721,O95747,O95487,O15078,P25490 10 +Mitotic cell cycle 0.3574466908075461 1.1036818532445936 0.2697311701702771 1.0 0.6873465842007428 323 Q96ST3,P46013,Q12834,Q96GD0,O75150,P83731,Q14676,Q9UN37,Q13564,P25205,Q9NZM5,O75528,O14974,Q9BSJ2,P43487,P48681,Q9NQS7,P0DMV9,Q7L2J0,Q9Y6D9,P27816,Q14980,Q9UNZ2,Q9BRX5,P54132,Q01082,Q13432,P51956,Q01130,P55072,Q96EE3,Q13464,P04083,Q9UQN3,O60885,P51608,Q9HD42,Q9UIG0,P40818,Q7Z3K3,O75147,P12270,O60934,Q02241,Q14141,Q15050,Q96JM3,Q9BV73,Q9NZZ3,P35658,Q9H444,Q15910,P61254,Q96EB6,Q99640,Q9H3R5,Q14807,Q9NYL9,Q9ULW0,Q9H7Z3,Q14978,P78536,Q9Y3E7,Q9H0H5,O75179,Q9H7N4,Q9Y448,P16949,Q96QE3,O14745,P35580,O00311,P54652,Q08379,P21333,O95347,Q14683,Q8WWK9,Q16513,P18583,Q13123,Q15398,Q96QC0,Q13526,Q14008,P62753,Q14203,Q01664,Q9UQE7,Q9UPT9,Q99496,Q86VI3,P33991,Q9Y6A5,Q9HC35 95 +Positive regulation of cell cell adhesion mediated by cadherin 0.6682753373133716 1.1023334039047867 0.2703167522282579 1.0 0.6873465842007428 4 Q07157,P55196 2 +Regionalization 0.3392336960012623 1.1019688037782491 0.2704752342770384 1.0 0.6873465842007428 32 Q8IZP0,Q12849,Q99496,Q12830,Q9Y366,O95747,P80723,O94788,Q8NCM8,P25490 10 +Protein autophosphorylation 0.3245575966805855 1.101622202570414 0.2706259517199862 1.0 0.6873465842007428 41 O60934,Q2M2I8,O95747,Q05682,Q9H2G2,Q92878 6 +Cardiac ventricle morphogenesis 0.568632990376095 1.1001343124274587 0.271273605706297 1.0 0.6883527013515364 6 Q9P2D1 1 +Regulation of histone modification 0.2969421739560062 1.100000138597068 0.271332061505424 1.0 0.6883527013515364 66 Q96ST3,O60885,O75528,Q13573,P51608,P26358,O75150,P18615,Q96EB6,P51610,P02545,Q9Y3Y2,P61088,Q92541,Q96L73 15 +Nuclear chromosome segregation 0.3101679439437272 1.0963954393715605 0.272905758935702 1.0 0.6918181758103679 119 Q8NBT2,Q9UQN3,Q12834,Q9Y3E7,Q9H0H5,Q13123,Q9HD42,Q15398,Q9UN37,Q9UIG0,P39748,Q7Z3K3,Q9Y448,P12270,Q02241,Q15050,Q96JM3,Q9NZZ3,Q9NQS7,P23246,Q9Y6D9,Q9H444,Q9UQE7,Q14980,Q14807,Q9Y6A5,Q9HC35,O95347,Q96EE3,Q14683 30 +Positive regulation of intrinsic apoptotic signaling pathway 0.4010280077125981 1.095793877568966 0.2731689884100592 1.0 0.6922220619200512 18 P23246,P61254,P62081,Q9NYF8,O14745 5 +Semaphorin plexin signaling pathway 0.5336363814102385 1.0944360020673911 0.2737638013224202 1.0 0.693465568216716 7 Q9NWH9 1 +Muscle cell development 0.3352769986558608 1.0932883123904673 0.2742672328312125 1.0 0.6939492233655671 34 Q9Y281,Q12802,O75147,Q13045,P42345,Q15149,Q9Y4W6,P02545,Q14315,Q9NYL9,Q16527,P12814,Q9H7B4,Q96HC4,Q00839,P25490 16 +Positive regulation of developmental growth 0.3417868362497565 1.0914472839036098 0.27507611610827 1.0 0.6951285331405689 29 Q9NZM3,Q9P2D1,Q9H2P0,P15311 4 +Protein localization to ciliary membrane 0.5666904325888863 1.0907519308368494 0.2753820531090309 1.0 0.6951857665071483 6 Q9UPT5,Q9NQ48,P36405,Q15276 4 +Negative regulation of natural killer cell activation 0.7596471885336591 1.0879767772927358 0.2766053596061493 1.0 0.6960552051170785 2 P30511 1 +Negative regulation of prostaglandin biosynthetic process 0.7596471885336238 1.087976777292588 0.2766053596062146 1.0 0.6960552051170785 2 Q96EB6 1 +Regulation of dna strand elongation 0.5323395730981444 1.0877546408099563 0.276703438748477 1.0 0.6960552051170785 7 Q9H981,Q9H1E3 2 +Negative regulation of hemopoiesis 0.5318558574113743 1.085263163545768 0.2778051159091155 1.0 0.6968138863654094 7 O15347,P04083,P38646 3 +Maturation of 5 8s rrna 0.3400147945168809 1.084461733447586 0.278160124908847 1.0 0.697441758427828 30 Q9H9Y2,Q14137,Q8IY81,Q15050,P78316,Q8N9T8,Q99547,Q9Y3B9,Q86U38 9 +Microtubule anchoring at centrosome 0.5650663836939146 1.0829118391633632 0.2788475563779464 1.0 0.6982930563900974 6 Q86VS8,Q14203,Q9Y496 3 +Establishment of protein localization to chromatin 0.5648149765464145 1.0816985035290356 0.2793865183331023 1.0 0.6988609305636417 6 O75367,Q9UFC0,Q9P0M6 3 +Dna ligation 0.4971854564467678 1.081532188999059 0.2794604501683491 1.0 0.6988609305636417 8 P18887,Q96T60 2 +Regulation of cellular response to growth factor stimulus 0.325055819851399 1.0792334492467024 0.2804836718951784 1.0 0.7002223080455477 39 P62942,Q8NC56,Q9BRX2,Q13526,Q13573,Q04721,Q14980,Q96EB6,Q9Y2U8,O14964,Q8N3R9,P78536,P08238,O00159 14 +Plasma membrane organization 0.3282022042233361 1.0783725013538434 0.2808675537002538 1.0 0.7003364355974235 37 O14745,Q9H444,Q9UQN3,Q9Y3E7,Q9Y2J2,Q9UKS6,Q8N3R9,Q01082,Q9UQB8,Q9HD42,P35579,Q15149,Q9UNF0 13 +Sensory organ development 0.2885814696137268 1.077453463321747 0.2812777303664386 1.0 0.7003406397546166 71 O14745,Q9P2D1,O75147,Q9Y467,Q9UM54,Q13308,Q04721,P11047,O95747,P20020,P83731,Q15648,O94788,O95487,Q15042,P48681,O15078,P25490 18 +Positive regulation of cytokinesis 0.4512038685901017 1.0772022319181582 0.2813899283973602 1.0 0.7003406397546166 12 Q7Z7K6,Q9H0H5,Q16513 3 +Regulation of mitochondrial rna catabolic process 0.6138862157119922 1.076665313084728 0.2816298140611635 1.0 0.7003425984604222 5 Q12849 1 +Replication fork processing 0.4596438615173259 1.074855833525869 0.2824392784735121 1.0 0.7012329877984546 11 Q86V81,Q9H1E3 2 +Glomerular epithelial cell development 0.7830162668872327 1.0732403123013208 0.283163307842047 1.0 0.7020595299008996 3 Q04721,P11047 2 +Biological process involved in intraspecies interaction between organisms 0.562135795831672 1.0687740779986918 0.285171482500266 1.0 0.7054632069872901 6 Q9HCK8 1 +Transforming growth factor beta receptor signaling pathway 0.3367708894013578 1.0641082785558718 0.2872796510159832 1.0 0.7073711034366491 31 P62942,P09874,Q13526,Q13573,Q9Y4E8,Q15942,Q9Y2U8,Q96EB6,P78536,P08238,Q8N3R9 11 +Positive regulation of cell division 0.4359749297404297 1.0633468069511156 0.2876247058663619 1.0 0.7073711034366491 13 Q7Z7K6,Q9H0H5,Q16513 3 +De novo protein folding 0.3813543132628098 1.0621391991199596 0.2881724969569297 1.0 0.7073711034366491 21 P0DMV9,Q9NYU2,P54652,Q99543,P25685,P61604,Q9NXW2,P11142 8 +Regulation of vascular associated smooth muscle cell differentiation 0.6585769442912303 1.0615386259866424 0.2884451887331827 1.0 0.7075190895951632 4 P26358,Q53EL6,P32929 3 +Vascular associated smooth muscle cell differentiation 0.6585769442912303 1.0615386259866424 0.2884451887331827 1.0 0.7075190895951632 4 P26358,Q53EL6,P32929 3 +Mitochondrial dna repair 0.7797090239974656 1.060545266674614 0.2888966077942869 1.0 0.707680714759399 3 P09874 1 +Positive regulation of cell cycle g1 s phase transition 0.3810907154397704 1.060011235659575 0.28913948781555 1.0 0.7079188782900382 21 Q7L2J0,Q15910,P78536 3 +Innate immune response 0.3195827054776699 1.0592244770000063 0.2894975602126313 1.0 0.7082749710380278 134 Q96ST3,Q9BY67,Q13283,P04083,O60858,Q9Y4E8,O15347,O75179,P30511,Q15648,Q6SZW1,Q13049,Q92974,Q9NR30,Q9NZI8,P33176,Q15233,Q13177,Q8IWZ3,Q96JM3,Q15942,Q16543,P51809,Q12846,P23246,Q9NY93,Q8WXF1,Q9H078,O75369,P08238,P39019,Q7Z434,P04406,Q96PK6,P26583,P78540,O14802,Q96SB4,P43243,P14373,Q92499,Q9UN86,P40429,O00159,O60828,O94992 46 +Ureter development 0.7789012703022056 1.0574470813655317 0.2903075938687629 1.0 0.7091853669746443 3 O95747 1 +Macromolecule deacylation 0.3175797520605387 1.0570070151187814 0.2905083858411594 1.0 0.7091853669746443 43 Q96ST3,Q15014,P23246,Q16576,Q96PK6,P51956,O75528,Q9UHR5,Q8WXI9,Q96EB6,Q86YP4,P21333,O94776 13 +Establishment or maintenance of bipolar cell polarity 0.3859803026547478 1.055937811867875 0.2909966276033078 1.0 0.7093032381557431 20 Q13308,P15311,Q5EBL8,Q8N3R9,O14745 5 +Dephosphorylation of rna polymerase ii c terminal domain 0.751929437706732 1.0557173155249593 0.291097383813121 1.0 0.7093032381557431 2 Q9NQG5 1 +In utero embryonic development 0.2888582314638646 1.0556195085440063 0.2911420844032577 1.0 0.7093032381557431 98 Q7Z6E9,Q9P2D1,O43772,P20290,O60934,Q4VCS5,Q12830,Q96AY3,Q9HCK8,Q15648,P35579,Q92541,P26373 13 +Trabecula morphogenesis 0.7781513105846254 1.054571442401937 0.2916213703555359 1.0 0.7093032381557431 3 Q9P2D1 1 +Heart trabecula morphogenesis 0.7781513105846254 1.054571442401937 0.2916213703555359 1.0 0.7093032381557431 3 Q9P2D1 1 +Positive regulation of protein import 0.3904286246980922 1.0517501720645757 0.2929141854679153 1.0 0.7108904566802375 19 P12270,Q7Z434,Q9NPF5,Q9NW64,P21333,P08238,O14737,O95071,Q05655 9 +Histone h4 acetylation 0.347018352285544 1.0506874324721347 0.2934021699182727 1.0 0.7115176839659674 26 Q15014,Q9HAF1,Q9UPT9,Q9NPF5,Q15906 5 +Positive regulation of protein deubiquitination 0.7768099275913946 1.04943018656813 0.2939801709880723 1.0 0.7115176839659674 3 Q9NZM5 1 +Dendritic cell differentiation 0.6556428839252859 1.049221790999047 0.2940760516372451 1.0 0.7115176839659674 4 P01889,Q04721 2 +Regulation of mrna catabolic process 0.2763680812846628 1.049091230395161 0.2941361319054767 1.0 0.7115176839659674 77 P06748,Q13464,P11940,O75175,P52272,Q6PKG0,Q6P6C2,Q9Y2W1,Q13151,Q8IZD4,P98175,Q8NC51,Q92945,Q13310,Q6PJT7,Q9NZI8 16 +Negative regulation of protein modification by small protein conjugation or removal 0.319811402416863 1.0490662531976935 0.2941476266375686 1.0 0.7115176839659674 41 Q12834,Q04323,P62841,P62913,P62081,P46777,Q9NP66 7 +Establishment of mitotic spindle localization 0.4057247598829695 1.047339459938662 0.2949430427625013 1.0 0.711924112639052 15 Q96SN8,Q14203,Q7Z460,Q14980,Q9UNZ2,P26367 6 +Positive regulation of epidermis development 0.5570697137904653 1.044366342624608 0.2963159293747117 1.0 0.7131707808866797 6 Q14980,Q15648 2 +Positive regulation of epidermal cell differentiation 0.5570697137904653 1.044366342624608 0.2963159293747117 1.0 0.7131707808866797 6 Q14980,Q15648 2 +Negative regulation of protein binding 0.3368081971151653 1.0430178403611217 0.2969400301687912 1.0 0.7138991270243548 29 Q13464,P30533,P10586,Q08379,Q9H2P0,P48681 6 +Regulation of mitotic centrosome separation 0.7748447270731843 1.041903003025722 0.2974566517070709 1.0 0.7146057549019573 3 Q9UNZ2 1 +Positive regulation of interferon beta production 0.4541311317990051 1.0411797837449432 0.2977921164561987 1.0 0.7146057549019573 11 P26583,O14802 2 +Regulation of respiratory burst 0.7746284017018856 1.0410747983867292 0.2978408348436296 1.0 0.7146057549019573 3 P39019 1 +Response to hydroxyurea 0.5232026237687442 1.0407646126720231 0.2979848074328486 1.0 0.7146057549019573 7 Q5TDH0,Q9UNS1,P54132 3 +Regulation of cellular response to hypoxia 0.6534000553792577 1.0398153043423048 0.2984257173993434 1.0 0.7154055880944318 4 O75116,Q9Y4L1 2 +Development of secondary female sexual characteristics 0.7742210828051478 1.0395155757305703 0.2985650179692141 1.0 0.7154820682413324 3 Q15648 1 +Pyrimidine nucleobase metabolic process 0.4450904647493617 1.038771166478349 0.2989111741733192 1.0 0.7155667908027296 12 P42345,Q05682 2 +Pteridine containing compound metabolic process 0.3976606506821047 1.0387465993600205 0.2989226026424492 1.0 0.7155667908027296 17 P00374,P13995 2 +Negative regulation of oxidative stress induced cell death 0.4536235634446214 1.0380838541735755 0.2992310175994865 1.0 0.7160477870861277 11 Q9NWH9,Q15233 2 +Regulation of integrin mediated signaling pathway 0.7475192943770752 1.0373364048599245 0.2995791051352992 1.0 0.7163946688877653 2 P21333 1 +Auditory receptor cell development 0.5549828073483313 1.034324839787255 0.3009843281748194 1.0 0.7193538518451209 6 O14745 1 +Regulation of intracellular protein transport 0.2714280372366128 1.0333121229389766 0.3014578558084479 1.0 0.719643507217091 82 Q9UII2,Q9UPN4,P12270,P49257,Q9NPF5,Q99496,Q8NBM4,Q14978,Q7Z6Z7,O15078,O00159,P21333,Q8IWJ2,Q9GZY8 14 +Response to salt 0.6041379310344692 1.0330056782132369 0.3016012413919493 1.0 0.719643507217091 5 P09651,Q9UER7,P52758,Q14103 4 +Inner ear receptor cell stereocilium organization 0.6038954881391001 1.031921816393945 0.3021087449169637 1.0 0.719900615549467 5 O14745 1 +Regulation of defense response to virus by host 0.5212159338043443 1.030569522782451 0.3027427343188051 1.0 0.7203193652904079 7 Q7Z434,O60828 2 +Protein containing complex disassembly 0.2982887279756054 1.0305390779127064 0.3027570178193497 1.0 0.7203193652904079 110 Q9Y281,P46821,Q96GM5,Q8WWK9,Q9UQN3,Q96GD0,Q9Y3E7,Q9Y3E1,Q99661,Q9Y5B9,Q92922,P35611,Q12824,Q92974,Q9HD42,O15344,O00139,Q9UN37,P33176,Q9NP79,P35241,Q66K74,Q969G3,P16949,Q13813,Q9UMX0,Q9NZZ3,O14497,P48681,Q14008,P51809,O95104,Q9H444,Q13045,Q7Z460,P17096,Q99961,O95721,Q9UHB6,Q9NYL9,Q01082,Q9ULW0,Q14197,Q8TAQ2,Q9H269,Q86Y91,P53990,P55072,P47755,P11142 50 +Defense response to symbiont 0.2895028256231283 1.0303320064617074 0.3028541792522414 1.0 0.7203193652904079 68 Q96ST3,Q13283,Q53F19,Q9Y3E7,Q7Z434,O14802,O60858,Q9NZM5,Q12906,P14373,Q92499,O75179,Q13049,O60828,Q9NZI8 15 +Regulation of innate immune response 0.3009755893418516 1.0282551116928873 0.3038298402622446 1.0 0.7221242939090522 52 Q96ST3,Q9BY67,Q9Y4E8,P30511,Q15648,Q9NZI8,Q15233,Q13177,Q16543,P19474,P23246,Q8WXF1,Q7Z434,P08238,P39019,Q96PK6,P26583,P43243,O60828,O94992 20 +Branching involved in blood vessel morphogenesis 0.602508162263552 1.0257216535708933 0.3050228046707322 1.0 0.7225696174201627 5 Q96T37 1 +Scarna localization to cajal body 0.6497517926089407 1.0245313606928492 0.3055843660854556 1.0 0.7225696174201627 4 P50991,O60832,P78371 3 +Negative regulation of amino acid transport 0.7442116868798415 1.0235780895628424 0.3060345985214947 1.0 0.7225696174201627 2 O75915 1 +Negative regulation of amine transport 0.7442116868798415 1.0235780895628424 0.3060345985214947 1.0 0.7225696174201627 2 O75915 1 +Prolactin secretion 0.7442116868798192 1.0235780895627498 0.3060345985215384 1.0 0.7225696174201627 2 P04083 1 +Mitochondrial depolarization 0.6018048400911087 1.0225797242289572 0.3065066002745928 1.0 0.7225696174201627 5 Q9UII2 1 +R loop disassembly 0.7695064791838968 1.0214878562397935 0.3070233596675236 1.0 0.7225696174201627 3 Q9BUQ8,Q9NR30 2 +Spleen development 0.6490016857085632 1.0213916023108716 0.3070689423958228 1.0 0.7225696174201627 4 P78536 1 +Neural crest cell differentiation 0.4423037133838548 1.0212950243633685 0.3071146830730253 1.0 0.7225696174201627 12 P19022,Q14978,Q13428 3 +Mesenchymal cell development 0.4423037133838548 1.0212950243633685 0.3071146830730253 1.0 0.7225696174201627 12 P19022,Q14978,Q13428 3 +Cell morphogenesis involved in differentiation 0.317834362995864 1.0202937395094407 0.3075891715685117 1.0 0.723317705961675 135 Q96ST3,P46821,Q13464,Q8IZP0,Q9NWH9,P46108,Q9BVA1,Q9Y4W6,P83731,Q96N67,Q6SZW1,Q9NZI8,Q96HC4,P33176,O75955,P07942,P18206,Q13177,O75147,Q13740,Q66K74,Q9ULV4,Q04721,Q14444,P16949,O75592,Q9UJU6,Q9UNW9,P19022,P50570,Q9Y639,Q8WX93,O95487,P07900,P12814,P26367,O14745,Q14247,P84095,Q9BPU6,P11047,Q8N8S7,O75369,P08238,P35579,Q9H2P0,Q15334,O43707,P60903,Q9ULH0,Q9UQ16,Q8N0X7,P53990,Q9UQB8,O60828,P21333 56 +Pyrimidine ribonucleoside triphosphate metabolic process 0.4722042412553314 1.0175713351672746 0.3088817155312116 1.0 0.7253330944197854 9 Q05682,P27144,Q9UIJ7 3 +Cell morphogenesis involved in neuron differentiation 0.2890569666796028 1.0139345980705683 0.310613960951785 1.0 0.7278620348509844 101 Q96ST3,P46821,Q8IZP0,Q9BVA1,Q9Y4W6,P83731,Q96N67,Q6SZW1,Q96HC4,Q9NZI8,P33176,O75955,P18206,Q13177,Q13740,O75147,Q66K74,Q04721,Q14444,P16949,O75592,Q9UJU6,Q9UNW9,P19022,P50570,Q9Y639,Q8WX93,O95487,P07900,O14745,Q14247,P84095,Q9BPU6,P11047,Q8N8S7,P08238,Q9H2P0,Q9ULH0,Q9UQ16,P53990,Q9UQB8,O60828 42 +Regulation of protein autophosphorylation 0.4573482464592637 1.0125038548242065 0.3112972045055742 1.0 0.7292060395274736 10 Q92878 1 +Transcription preinitiation complex assembly 0.4405056396353002 1.0100346486867666 0.3124786900710741 1.0 0.7301764409868452 12 Q9UIF9,Q00403,Q12962,P17480,P62333,O15160,Q12824,P09429 8 +Dna topological change 0.5496641740614148 1.0087712909453843 0.3130843325241099 1.0 0.7305180003212217 6 P26583 1 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.4402956618740791 1.00872050519933 0.3131086949063131 1.0 0.7305180003212217 12 O75179,Q9NZM5,Q9H078 3 +Positive regulation of mitotic cell cycle 0.3099036861224549 1.0080137969026768 0.313447838799048 1.0 0.7305180003212217 45 Q96ST3,Q96QC0,P04083,Q7L2J0,Q9UPT9,Q16513,O60885,O00311,P51608,P54652,O75179,Q9NYL9,P78536,Q15398 14 +Regulation of biomineralization 0.4701467811848786 1.0058473917738675 0.3144889860284094 1.0 0.7305180003212217 9 Q13464,Q9NUQ3,P04920,O95747,P20020,O75116 6 +Coronary vasculature development 0.4831840819711663 1.0043876550411857 0.3151917980129277 1.0 0.7311342522669241 8 Q13308,Q8NCM8 2 +Regulation of cell cycle checkpoint 0.4269183664057502 1.0043845975569723 0.3151932711664074 1.0 0.7311342522669241 13 Q13769,Q96QC0,P12270,Q9Y6D9 4 +Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway 0.7392502756339914 1.0029873948621653 0.3158669431357794 1.0 0.7321638758977753 2 Q9Y4L1 1 +Negative regulation of cellular response to hypoxia 0.7392502756339914 1.0029873948621653 0.3158669431357794 1.0 0.7321638758977753 2 Q9Y4L1 1 +Intermediate filament based process 0.4133263454484892 1.0025607935292424 0.3160728204925394 1.0 0.7321638758977753 14 P07197,P48681,O75190,P58107 4 +Regulation of response to interferon gamma 0.7645437000275691 1.002552653357599 0.3160767497871513 1.0 0.7321638758977753 3 Q16543,Q15648 2 +Anterior posterior pattern specification 0.3621872397834845 1.001734877758162 0.3164716568900485 1.0 0.7323165357503546 23 Q8IZP0,Q12849,Q99496,Q12830,O95747,P80723,O94788 7 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.3325435363897856 1.0017332843638114 0.3164724266624543 1.0 0.7323165357503546 29 Q04323,Q9NZM5,P62081,P62913 4 +Protein demannosylation 0.5962082817853991 0.9976118277007402 0.318467623472487 1.0 0.7350069564191684 5 P33908,O60858 2 +Golgi ribbon formation 0.5146279552899462 0.9968281663945636 0.3188479239633039 1.0 0.7352595602089066 7 Q08379,Q8IWJ2,Q92614 3 +Demethylation 0.3918862698407428 0.9963728128784594 0.3190690375320097 1.0 0.7355148539924737 17 Q6P6C2,Q9Y2K7 2 +Face development 0.4465157013699629 0.9948236740858248 0.3198220299458065 1.0 0.7362316390804987 11 Q9P2D1,O94788 2 +Protein localization to nucleolus 0.4464172024022812 0.9942255145919512 0.3201130890906407 1.0 0.7365720345518705 11 Q9NZM5 1 +Positive regulation of sister chromatid cohesion 0.5951390700686033 0.9928488670676552 0.3207836114596687 1.0 0.7365720345518705 5 O75367,P23246,P39748 3 +Positive regulation of telomerase activity 0.3949402281930571 0.992716800240738 0.3208479853311825 1.0 0.7365720345518705 16 O15381,P50991,Q96T60,O60832,P13010,P78371,P08238,P17987,P07900,P27361 10 +Neuron cellular homeostasis 0.5133830911902004 0.9904647701790504 0.3219470005906955 1.0 0.7365720345518705 7 Q14203,Q9UQN3 2 +Ear development 0.3313076608156235 0.989808144159792 0.3222679033595996 1.0 0.7365720345518705 29 Q9P2D1,Q9UM54,Q13308,O15078,O14745 5 +Cell cycle g2 m phase transition 0.3024889308802302 0.989640032303688 0.3223500956354517 1.0 0.7365720345518705 48 Q96ST3,P06748,Q13564,O60885,O60934,Q9NZM5,P51608,O00311,P54652,P54132,Q96QE3,P48681,Q9UN37 13 +Rna dependent dna biosynthetic process 0.3196229392435245 0.9878100823004377 0.3232456688259484 1.0 0.7382456790258719 37 P09651,P07910,P50991,Q01780,Q96T60,O60832,Q9NPE3,P49959,P13010,P08238,P78371,P27361,P17987,Q9NYB0,Q92878,P35251,P07900,Q00839 18 +Myeloid cell differentiation 0.2684372834799442 0.98653496677157 0.3238706652407441 1.0 0.739166280176032 79 Q8IYB5,Q8IZP0,O15347,Q15648,Q9H9B4,P62805,Q9UII2,Q04721,Q6IAN0,O95628,O00165,P62753,P0DMV9,Q96T37,Q9UKV3,Q96EB6,Q9NYL9,P39019,Q13769,P35579,Q13310,Q9GZZ9,P62263,P26583,P09874,P42345 26 +Negative regulation of i kappab kinase nf kappab signaling 0.5446751632627742 0.9848561124477342 0.3246947535415021 1.0 0.7399111897273037 6 O60826 1 +Regulation of unsaturated fatty acid biosynthetic process 0.7598566308243708 0.9847112448735952 0.3247659276596928 1.0 0.7399111897273037 3 P04083,Q96EB6 2 +Striated muscle adaptation 0.544356780353922 0.9833318673869884 0.325444130903803 1.0 0.7404743169676009 6 Q15910 1 +Regulation of dna dependent dna replication initiation 0.6396136807858239 0.9821814364554564 0.3260104712417351 1.0 0.7411354790218807 4 O60934 1 +Microtubule anchoring 0.4102194992301206 0.981612153647579 0.3262909576660426 1.0 0.7411354790218807 14 Q8TD16,Q86VS8,Q8IWJ2 3 +Water soluble vitamin metabolic process 0.3394502156973484 0.9810091915751648 0.3265882088817173 1.0 0.7413051610119253 26 P11166,P13995,Q96GD0,O14678,P00374 5 +Negative regulation of bmp signaling pathway 0.5917241379310305 0.9776528734276816 0.3282460373200064 1.0 0.743684627546328 5 Q9Y2U8,Q8N0X7,Q9UPN9,Q8NC56 4 +Histone h4 k5 acetylation 0.5916742043521915 0.977430865529389 0.3283558886112212 1.0 0.743684627546328 5 Q9HAF1 1 +Cilium movement 0.443563115007519 0.9769105856527982 0.3286134206730651 1.0 0.743684627546328 11 Q9UPN4,O14745 2 +Regulation of cytokinesis 0.3299232301091567 0.9764719764787948 0.3288306284667746 1.0 0.743684627546328 29 O75400,Q16513,Q8WYP5,Q96GD0,Q9H0H5,Q13526,Q7Z7K6,Q9UN37 8 +Protein acylation 0.288016753459561 0.9764037134336452 0.3288644420221378 1.0 0.743684627546328 66 Q96ST3,Q15014,Q9HAF1,Q9UPT9,Q9NPF5,P51610,P51608,Q9NPA8,Q9BX68,Q8IUH4,Q9NRF9,Q6ZRS2,Q15906 13 +Actin polymerization or depolymerization 0.2958378433538566 0.9737492776459058 0.3301810433565904 1.0 0.7455278357297793 55 Q9Y281,Q8IZP0,Q96GD0,P35611,P62993,P35241,O75146,Q9UJU6,Q13813,Q14247,O00165,P59998,Q9UHB6,Q8N8S7,Q9NYL9,Q01082,O60610,P42345,P47755,Q9UQB8,Q05655 21 +Regulation of bicellular tight junction assembly 0.5098311997329948 0.9723321001159696 0.3308853593216021 1.0 0.7455278357297793 7 O00159,Q13464,Q07157 3 +Histone modification 0.3318232723026228 0.971646671885894 0.3312263553258119 1.0 0.7455278357297793 161 Q96ST3,Q15014,O60885,Q9NPF5,Q13573,P51608,O75150,Q9UHR5,Q86YP4,Q7Z6Z7,Q92541,Q9UIG0,Q9HAF1,Q16576,P16402,O75528,Q8WXI9,Q13043,P61088,Q9NQS7,Q9Y2K7,P16403,P10412,P23246,Q15910,Q9UPT9,P26358,Q99496,Q9NPA8,Q96EB6,P02545,Q7LBC6,Q6ZRS2,Q96L73,O94776,Q96PK6,Q15291,P18615,P51610,Q9Y3Y2,Q9H7B4,Q9NRF9,Q15906 43 +Regulation of organelle assembly 0.2875140197845275 0.9695060407156394 0.3322927677383711 1.0 0.7470831613682297 66 Q13283,Q9UQN3,Q9Y3E7,Q9UHD8,Q9HD42,O95219,P26038,P12270,P15311,Q15555,P50570,Q9NZZ3,P06748,P0DMV9,Q9H444,P27816,Q14980,Q9NT62,Q15042,Q4KMP7,Q96PK6,Q9UN86 22 +Negative regulation of tumor necrosis factor superfamily cytokine production 0.540754179275646 0.9661019116432435 0.3339931880735087 1.0 0.7491793329783553 6 P14373,Q9UBC1 2 +Positive regulation of cellular biosynthetic process 0.2841166209735843 0.9627996156787592 0.3356480936458708 1.0 0.7524910027888189 426 Q96ST3,Q9NWH9,O60858,Q6PKG0,O00233,P38159,Q13049,Q92974,Q9NZI8,O15078,Q9P2D1,P82094,P17480,O75528,O14974,Q12906,P52815,Q9H981,Q86V81,P25490,P06748,Q7L2J0,P23246,Q96T37,O14776,Q9NPA8,Q9H1B7,Q9BRX5,Q9BY77,Q9HCK8,P54132,Q13769,Q96CT7,Q15042,Q9NYF8,Q96I24,Q96L73,Q8IVW6,P17980,P14373,P55072,Q8WVB6,Q15014,P04083,Q14249,O60885,O60869,Q13573,P51608,O60832,P13984,P98179,Q99543,Q92922,Q5VUA4,Q9NR30,Q9UIG0,Q9UER7,Q8IX12,Q9Y2W1,P53999,P84095,P61254,P19338,Q99459,P11940,P26583,P18615,Q14978,Q9H7B4,Q92785,Q15648,Q9H7N4,P51858,Q12830,Q9NXV6,Q96QE3,Q9Y467,Q9UM54,Q6ZRS2,Q96PK6,O00311,Q08379,Q9NQG5,Q8WWK9,O95747,Q96T23,Q92604,Q8WUB8,Q13526,Q01664,Q9UPT9,O95785,P46777,Q7Z434,Q96T60,P09874,P42345,P51610,Q8NCF5,Q9H1E3,Q9BZI7,O60828 103 +Transforming growth factor beta production 0.6345356642555267 0.9610449087948209 0.3365295879345555 1.0 0.753600038594961 4 P08238,Q9Y5K6 2 +Srp dependent cotranslational protein targeting to membrane signal sequence recognition 0.7287761852260151 0.9597194590027022 0.3371964270553809 1.0 0.7540794216324094 2 P61011 1 +Spindle midzone assembly 0.5069250077884762 0.9575233124199756 0.3383031854989879 1.0 0.7551489987780561 7 Q9H0H5,Q9NQS7 2 +Endosomal transport 0.2777947118606253 0.9573034216369872 0.3384141288202484 1.0 0.7551489987780561 93 Q9UQN3,Q9Y3E7,O60271,Q9NZM3,Q9HD42,Q9UN37,O60493,O43752,Q9NP79,Q567U6,Q9NZZ3,Q8IWJ2,Q9H444,Q14203,P49257,Q9H4M9,Q15075,O60826,O14964,Q07960,Q9Y5X2,Q4KMP7,P14373,P55072 24 +Regulation of protein localization to nucleus 0.2951926834803604 0.9566930899627096 0.3387221869052843 1.0 0.7551489987780561 52 Q7L2J0,P12270,P09874,Q9NPF5,Q13526,Q9Y5K6,P02545,Q14978,Q7Z434,P21333 10 +Steroid hormone mediated signaling pathway 0.3125325573821565 0.9560245985555538 0.3390598069276136 1.0 0.7551489987780561 40 Q9UER7,Q15424,P82094,P09874,O75528,Q14151,Q8TDD1,Q15648,Q9GZZ9 9 +Positive regulation of ubiquitin protein transferase activity 0.4063485004355813 0.955585899688486 0.3392814880658714 1.0 0.7551489987780561 14 Q13526,Q12834 2 +Regulation of bmp signaling pathway 0.4399353136349642 0.9549525735882176 0.3396016812277178 1.0 0.7551489987780561 11 Q8NC56,Q9BRX2,Q14980,Q04721,Q9Y2U8 5 +Positive regulation of type i interferon mediated signaling pathway 0.7517468123694364 0.9539452297177315 0.340111367103038 1.0 0.7552075705455281 3 Q7Z434 1 +Regulation of intracellular steroid hormone receptor signaling pathway 0.3362973864317378 0.9521633556291764 0.341014142092257 1.0 0.7563968581934746 26 Q9GZZ9,Q14151,Q15648 3 +Regulation of cell matrix adhesion 0.3285152808197385 0.9490816832769876 0.3425790695078707 1.0 0.7586777005773924 27 Q13464,P60903,P18206,Q9ULV4,Q9H2G2,O75116,Q13630,P46939,P49593 9 +Morphogenesis of embryonic epithelium 0.32766840779361 0.9472544067049384 0.3435091575381568 1.0 0.7590706901502691 28 Q12849,Q13308,Q9Y366,O95747,P62081,P25440,O94788,Q8N3R9 8 +Myofibroblast differentiation 0.7254685777287777 0.9461176334411256 0.3440885907988869 1.0 0.7592971818159264 2 P09874 1 +Negative regulation of vascular associated smooth muscle cell differentiation 0.7254685777287713 0.9461176334410988 0.3440885907989006 1.0 0.7592971818159264 2 P26358 1 +Negative regulation of jun kinase activity 0.725468577728771 0.9461176334410968 0.3440885907989015 1.0 0.7592971818159264 2 P31689 1 +Positive regulation of cell killing 0.4722105927930201 0.9443286780222804 0.3450017154401927 1.0 0.7599870472040533 8 Q9BY67 1 +Positive regulation of type i interferon production 0.376128814091546 0.9423106908837846 0.3460335962475547 1.0 0.7610682793665267 19 Q7Z434,Q13283,P26583,O14802 4 +Formation of extrachromosomal circular dna 0.582626264739746 0.9373008657383874 0.3486038177634341 1.0 0.7653457742415614 5 O60934 1 +Platelet activation 0.3870415207060738 0.9362982814185884 0.3491196327700394 1.0 0.7660461564409066 16 P35579,P18206,Q9Y490 3 +Cytokine production 0.2930932238028292 0.9357704693517652 0.3493913790281395 1.0 0.7660461564409066 111 Q9BY67,Q13283,P04083,Q9Y6M1,P30511,P46940,Q13049,Q92974,Q9UBC1,Q9NR30,Q9NZI8,P82094,Q9Y5K6,P15311,P25490,P0DMV9,Q15910,Q9NY93,Q99496,Q96EB6,Q9UJZ1,Q01082,P08238,Q7Z434,P04406,P26583,P78540,O14802,Q8NCF5,P14373,P20020,Q92499,P78536,O75116,O60828,Q02952 36 +Pyrimidine ribonucleotide metabolic process 0.436591874409789 0.9347702725349256 0.3499067027994114 1.0 0.7660461564409066 11 Q05682,P27144,Q9UIJ7 3 +Negative regulation by host of viral process 0.7461380922563672 0.932751292450432 0.3509483949943659 1.0 0.766413928479735 3 Q9H1E3 1 +Lung morphogenesis 0.4572439543271051 0.9326665600007188 0.3509921556140321 1.0 0.766413928479735 9 P27361,O95487,O60568,Q13247 4 +Negative regulation of fibroblast apoptotic process 0.7460967978192974 0.9325955202822452 0.3510288471996683 1.0 0.766413928479735 3 Q9HCK8 1 +Cellular response to testosterone stimulus 0.7457954232147762 0.9314587876485368 0.3516162933882185 1.0 0.766413928479735 3 O75116,Q96EB6 2 +Membrane to membrane docking 0.745795423214776 0.9314587876485352 0.3516162933882194 1.0 0.766413928479735 3 Q13464,P15311 2 +Positive regulation of striated muscle cell differentiation 0.5017835965807946 0.9313907210599351 0.3516514889180455 1.0 0.766413928479735 7 Q13049,Q15014 2 +Negative regulation of centrosome duplication 0.6273721199774558 0.9313253618985082 0.351685286605006 1.0 0.766413928479735 4 P06748,Q96PK6 2 +Caveolin mediated endocytosis 0.6271373414230458 0.9303534000259884 0.3521881377759044 1.0 0.7667644289782514 4 P27361,Q13432,Q9UNF0 3 +Positive regulation of peptidyl tyrosine phosphorylation 0.3648749419091125 0.930094771002328 0.3523220179151183 1.0 0.7667644289782514 21 Q13177,Q13432,Q8IZP0,Q9H223,P42345,P22059,P78536,Q92974,Q9H2P0,O00165 10 +Regulation of transcription by rna polymerase iii 0.4276709691459705 0.9300747153193892 0.3523324011490627 1.0 0.7667644289782514 12 P42345,Q9NR30,Q9HCK8,Q9UIG0 4 +Regulation of phosphoprotein phosphatase activity 0.3827759481759682 0.92996927052437 0.352386995244768 1.0 0.7667644289782514 17 P62942,Q13464,P42345,O14974,O75116,P67870,P08238 7 +Viral gene expression 0.3029825362006864 0.9289642538387468 0.3529076118214735 1.0 0.7673206625178384 45 P05455,P26599,Q96T23,Q01664,O60858,Q13573,P41214,P17980,Q9H1E3,P14373,P26572,Q13049 12 +Membrane raft assembly 0.5326222133762175 0.927337085713524 0.3537515449294846 1.0 0.7688123756657042 6 P60903,Q9UNF0 2 +Regulation of canonical wnt signaling pathway 0.3072657999014807 0.9258145538693732 0.3545423623925567 1.0 0.7693684750030011 42 Q13283,Q13308,Q8NBM4,P19022,Q9HCK8,P40818,O14745 7 +Neural precursor cell proliferation 0.3259028762593771 0.9245266887535112 0.3552121626037055 1.0 0.7697189920927968 27 Q86VS8,Q9H0H5,P48681,P19022,Q92974,Q9NZI8 6 +Nuclear membrane organization 0.3331661747450142 0.923637266909508 0.3556752040328237 1.0 0.7698207307559036 26 Q14203,Q9H444,Q9UQN3,Q9Y3E7,Q9UNZ2,Q5JTV8,Q9HD42,Q9NZZ3,Q9UN37 9 +Regulation of amyloid beta clearance 0.5315889238461278 0.9224251897352784 0.356306835532381 1.0 0.7700075639468312 6 Q13464 1 +Cell substrate adhesion 0.2859308859406801 0.920469074965248 0.3573276863966421 1.0 0.7700433513949536 64 Q13464,P46108,O60504,Q13136,P46939,P18206,P49593,P07942,Q9ULV4,Q15942,Q13043,P50570,Q14247,P12814,P42771,P11274,Q7Z460,P11047,O43707,P60903,Q9H2G2,O75116,Q13630,P21333,Q9NVD7 25 +Regulation of response to biotic stimulus 0.2776876609440729 0.9201684382911596 0.357484744812663 1.0 0.7700433513949536 71 Q96ST3,Q9BY67,Q96PK6,P26583,Q7Z434,Q9NZM5,Q8WXF1,P43243,O60828,O75179,P30511,Q15648,P39019,Q9UBC1,Q9NZI8,Q15233 16 +Negative regulation of platelet activation 0.7191289966923873 0.920137772855478 0.3575007674719412 1.0 0.7700433513949536 2 P80404 1 +Multicellular organismal movement 0.4415328219954348 0.9193443076533058 0.3579155094296387 1.0 0.7700433513949536 10 Q7Z406,P18887 2 +Type i interferon production 0.3326716568727931 0.9191439702943756 0.3580202730412072 1.0 0.7700433513949536 26 Q13283,P26583,O14802,P10809,P25490,Q7Z434,O60828,P19474,P07900,P04406,O75955 11 +Negative regulation of voltage gated calcium channel activity 0.7188533627342837 0.9190110198541326 0.3580898082590162 1.0 0.7700433513949536 2 P0DP25 1 +Metanephric epithelium development 0.5783303320669781 0.9183210190313122 0.3584508262547268 1.0 0.7702902148099413 5 O95747,P11047 2 +Germ cell proliferation 0.71857772877618 0.917884507399468 0.3586793333650191 1.0 0.7702902148099413 2 P20042 1 +Transcription by rna polymerase i 0.3242352814660328 0.914734451709234 0.3603310533861594 1.0 0.7726184350365608 28 Q9UIF9,Q13428,P17480,P19338,Q9NZM5,P42345,Q9NX58,Q9P0M6,O15160,O75367,P21333,P32780 12 +Response to aldosterone 0.7411339052991891 0.9139042718228853 0.360767148819342 1.0 0.7729074486712434 3 P09874 1 +Attachment of mitotic spindle microtubules to kinetochore 0.453888569516468 0.9137477390634136 0.3608494129336002 1.0 0.7729074486712434 9 Q96EE3,Q9Y6D9,Q99661,Q96JM3 4 +Cardiac septum morphogenesis 0.4660393129663352 0.9107510992304072 0.3624265333902414 1.0 0.7735300751582619 8 Q9P2D1,Q96T37 2 +Activin receptor signaling pathway 0.7402812241521897 0.9106990242241944 0.3624539783815348 1.0 0.7735300751582619 3 P62942,P67870 2 +Regulation of activin receptor signaling pathway 0.7402812241521897 0.9106990242241944 0.3624539783815348 1.0 0.7735300751582619 3 P62942,P67870 2 +Protein acetylation 0.2875794005171064 0.9093853222076924 0.3631467668095776 1.0 0.7741708033553298 61 Q96ST3,Q15014,Q9HAF1,Q9UPT9,Q9NPF5,P51610,P51608,Q9NPA8,Q9BX68,Q9NRF9,Q6ZRS2,Q15906 12 +T cell mediated cytotoxicity 0.4655722605063284 0.9082164818651398 0.3637638577928275 1.0 0.7748380419411544 8 Q9BY67 1 +Embryonic camera type eye development 0.7395978780358867 0.9081316406532888 0.3638086753515357 1.0 0.7748380419411544 3 P48681 1 +Gdp metabolic process 0.6212204152124114 0.905904316147226 0.3649864996200076 1.0 0.7758476705103775 4 Q14168 1 +Ribosomal large subunit export from nucleus 0.4965790725446325 0.9050313576094444 0.3654487749660178 1.0 0.7758507771904432 7 P06748,Q9NVU7 2 +Regulation of cytoplasmic translation 0.3851401518199535 0.9029797507802096 0.366536641967369 1.0 0.777307712112103 15 O60506,P11940,P42345,P14618,P40429,Q9Y5A9,Q9NZI8,Q06787,Q00839 9 +Negative regulation of leukocyte cell cell adhesion 0.3849553655198286 0.9016970717321704 0.367217808969154 1.0 0.7783662244201413 15 P04083,Q5JRA6,Q9Y6D9,P78540 4 +Cellular response to muramyl dipeptide 0.7371534256301414 0.8989574881705648 0.3686753049863966 1.0 0.7802143843136514 3 Q92974 1 +Positive regulation of cell matrix adhesion 0.4098393984733632 0.8942864359359014 0.3711686554205275 1.0 0.7834998676842695 13 Q13630,Q13464 2 +Mitotic cell cycle process 0.356344793555146 0.8923390985697883 0.3722112034568021 1.0 0.7837854856009211 271 Q96ST3,P46013,Q96GD0,Q12834,P83731,Q14676,Q9UN37,Q13564,P25205,Q9NZM5,P43487,P48681,Q9NQS7,P0DMV9,Q7L2J0,Q9Y6D9,P27816,Q14980,Q9UNZ2,Q9BRX5,P54132,Q01082,Q13432,P55072,Q96EE3,Q13464,P04083,Q9UQN3,O60885,P51608,Q9HD42,Q9UIG0,P40818,Q7Z3K3,O75147,P12270,O60934,Q02241,Q14141,Q15050,Q96JM3,Q9NZZ3,Q9H444,Q15910,P61254,Q99640,Q9H3R5,Q14807,Q9NYL9,Q9ULW0,P78536,Q9Y3E7,Q9H0H5,O75179,Q9Y448,P16949,Q96QE3,P35580,O00311,P54652,Q08379,P21333,O95347,Q14683,Q8WWK9,P18583,Q13123,Q15398,Q96QC0,Q13526,Q14008,P62753,Q14203,Q01664,Q9UQE7,Q86VI3,P33991,Q9Y6A5,Q9HC35 79 +Regulation of intrinsic apoptotic signaling pathway 0.2875568448277797 0.8923261049219601 0.3722181659701387 1.0 0.7837854856009211 59 P23246,P09874,P61254,P30040,P31689,Q96EB6,P62081,Q9NYF8,Q9UMX0,Q13049,Q92974,Q96QE3,Q9Y4L1,O14745,Q15233 15 +Response to bmp 0.3775639269304209 0.8922757235428541 0.3722451630803534 1.0 0.7837854856009211 17 Q53EL6,Q8NC56,Q9BRX2,Q14980,Q04721,Q9Y4E8,Q9Y2U8,Q8N0X7,P27361,P17844 10 +Negative regulation of lymphocyte differentiation 0.6177222706752498 0.8914939086857746 0.3726642579595982 1.0 0.7839677245314675 4 O15347 1 +Positive regulation of protein localization to cell periphery 0.3648117709554373 0.8908045184872838 0.3730340506747656 1.0 0.7844548123722501 20 P84095,O43491,Q14980,P15311,P33176 5 +Astral microtubule organization 0.6174397599710584 0.8903316226484053 0.3732878459786064 1.0 0.7844932586465224 4 Q14980 1 +Negative regulation of histone h3 k9 trimethylation 0.711411245865485 0.8886823114793335 0.3741738400931917 1.0 0.7851901526294587 2 Q96EB6 1 +Negative regulation of histone h3 k9 methylation 0.5715828331731232 0.8886173631338427 0.3742087563192031 1.0 0.7851901526294587 5 P26358,Q96EB6 2 +Positive regulation of rna metabolic process 0.3245951124416405 0.8881591791384832 0.3744551332556998 1.0 0.785459728510539 369 Q96ST3,Q9NWH9,O60858,O00233,P38159,Q13049,Q92974,Q9NZI8,O15078,Q9P2D1,P82094,P17480,O75528,O14974,Q12906,P52815,Q8IZD4,Q9H981,Q86V81,P25490,P06748,Q7L2J0,Q96T37,P23246,O14776,Q9NPA8,Q9H1B7,Q9BRX5,Q9HCK8,P54132,Q13769,Q96CT7,Q9NYF8,Q96I24,Q96L73,Q8IVW6,P17980,P14373,Q13464,Q15014,O60885,O60869,Q13573,P51608,P13984,P24928,P98179,Q99543,Q96E39,Q92922,Q5VUA4,Q9NR30,Q9UIG0,Q9UER7,Q7Z3K3,Q8IX12,O75175,O43709,Q9Y2W1,P53999,P05114,P84095,P08621,P17096,P19338,Q99459,Q96EB6,O94776,P17544,P11940,P26583,Q00059,P18615,Q14978,O75116,Q9H7B4,P11142,Q92785,Q15648,Q9H7N4,P51858,Q13243,Q71SY5,Q969G3,Q12830,Q9NVC6,Q9NXV6,P35251,P35269,P41223,O00165,Q9NY93,Q9Y467,Q9UM54,Q6ZRS2,Q96PK6,Q12849,Q9NQG5,Q8WWK9,O95747,Q92945,Q96T23,Q8WUB8,Q13526,Q01664,Q9UPT9,Q7Z434,P09874,P42345,P51610,Q8NCF5,Q9H1E3,O60828 113 +Regulation of protein deacetylation 0.3765595085771745 0.8850397715209872 0.3761351812539488 1.0 0.7875736046228125 17 P51956,O75528,Q96EB6 3 +Cell fate commitment 0.3640514033061992 0.8849495601966966 0.3761838363150283 1.0 0.7875736046228125 20 Q8N7H5,P42345,Q6P1J9,Q04721,Q96N67,Q92974,Q92541 7 +Maintenance of cell polarity 0.4923203590859569 0.8835396233223789 0.3769447839864965 1.0 0.7884587083850667 7 O14745 1 +Embryonic neurocranium morphogenesis 0.7086549062844487 0.877497237160804 0.3802166188449758 1.0 0.791810914268593 2 Q6UB35 1 +Response to interleukin 1 0.3752160132116257 0.8753760966273393 0.3813693014430603 1.0 0.7924773194677692 17 P25490,Q96JM3,P38159,Q9NZI8,Q02952 5 +Positive regulation of mitotic cell cycle phase transition 0.3121619597714672 0.8746425151735349 0.3817684471932736 1.0 0.7926427225499911 35 Q96ST3,Q7L2J0,P04083,O60885,O00311,P51608,P54652,O75179,Q9NYL9,P78536,Q15398 11 +Thrombin activated receptor signaling pathway 0.7304160693752937 0.8737546474095136 0.3822518836474013 1.0 0.7926427225499911 3 Q9NWH9 1 +Negative regulation of protein localization 0.2882283976043638 0.8731606131487024 0.3825755397446249 1.0 0.7926427225499911 53 Q96ST3,O60493,P20290,P49257,O00233,Q8NBM4,P30040,Q9UNZ2,P31689,Q6WKZ4,Q8N183,Q13438,Q9NQ48,Q13136 14 +Inositol metabolic process 0.7302246861044719 0.8730405685550473 0.382640965736833 1.0 0.7926427225499911 3 P51608 1 +Regulation of mitotic cell cycle phase transition 0.2732772078127609 0.8718390864316716 0.3832961681287294 1.0 0.7926427225499911 94 Q96ST3,P04083,O60885,P51608,Q13123,O75179,Q15398,Q9UN37,Q13564,P12270,O60934,Q9NZM5,Q96QE3,Q7L2J0,Q9Y6D9,Q15910,Q01664,P61254,Q9NYL9,P54132,O00311,P54652,P78536 23 +Neuron death in response to oxidative stress 0.4462937170304784 0.871127778838696 0.3836843880211273 1.0 0.7926427225499911 9 O75915,P09874,Q15233 3 +Histone h3 k9 trimethylation 0.5206524071184864 0.8706526112217995 0.3839438606961889 1.0 0.7926427225499911 6 P02545,P51608,Q96EB6 3 +Regulation of ubiquitin specific protease activity 0.7295827022151415 0.8706459973134473 0.3839474730814802 1.0 0.7926427225499911 3 Q04323 1 +Cellular response to lipid 0.2851623229795003 0.8681974485892527 0.3852862507523873 1.0 0.7937222276128458 107 O95071,P04083,Q96GM5,Q13573,Q14151,O95747,Q8TDD1,Q15648,Q9UBC1,P11802,P26038,P40818,Q9UER7,P82094,O75528,Q6P1J9,Q96JM3,Q9NZZ3,Q00839,P0DMV9,Q01664,P11274,Q13308,Q9P1Z2,Q96EB6,Q13185,Q9GZZ9,Q15424,P26583,P09874,Q53EL6,Q8N7H5,Q9NS86,P20020,O75116,Q9H7B4,O94788,P11142 38 +Regulation of telomere maintenance via telomere lengthening 0.3267279548120599 0.865415973614485 0.3868105167535232 1.0 0.79633240500988 26 P09651,P07910,P50991,Q01780,Q96T60,P09874,O60832,P13010,P78371,P22626,P27361,P17987,Q00839 13 +Regulation of vasculature development 0.3049941864735642 0.864727710770907 0.387188256252301 1.0 0.7965883037989702 39 Q13464,P55011,Q4VCS5,P51608,Q96JM3,Q9UGM6,O14964,O96013 8 +Muscle hypertrophy in response to stress 0.5660883976618716 0.8645359637630139 0.3872935328737412 1.0 0.7965883037989702 5 Q15910 1 +Regulation of mrna polyadenylation 0.3923224296853007 0.8621149937564756 0.3886242412750924 1.0 0.7969362591184305 14 Q8N684,Q6PJT7,Q5VTR2,P18615,O75150,O00267,P09012 7 +Arf protein signal transduction 0.727116668558253 0.8614588862736539 0.3889853557088201 1.0 0.7969362591184305 3 Q8N6T3 1 +Positive regulation of bmp signaling pathway 0.5185673530520529 0.8608307802751556 0.3893312497091914 1.0 0.7969362591184305 6 Q14980,Q04721 2 +Regulation of cell cycle phase transition 0.295809067651467 0.8606190821376373 0.3894478726874522 1.0 0.7969362591184305 120 Q96ST3,P04083,P51608,Q13123,O75179,Q9UNS1,Q14676,Q15398,Q9UN37,Q13564,Q96QC0,P12270,O60934,Q9NZM5,Q96QE3,P06748,P16104,Q7L2J0,Q9Y6D9,Q15910,Q01664,P61254,Q99459,P54132,Q13769,O00311,P54652,P78536 28 +Angiotensin activated signaling pathway 0.7262056176748183 0.8580693193049479 0.3908541875310503 1.0 0.7984255306915846 3 Q13464 1 +Mesenchymal cell differentiation 0.3070587251160089 0.8573928528636924 0.3912278078808127 1.0 0.7987617701814202 37 Q13464,Q15910,Q13428,P42345,O95747,P19022,Q14978,P21333 8 +Negative regulation of neuron death 0.2981321051023723 0.8566823489185115 0.39162046093858 1.0 0.7991346966070225 44 Q13464,Q9H444,P51608,Q9H2P0,P30511,P51858,P48681,Q9Y4L1 8 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.4156014041908502 0.8557114083352538 0.3921574283275633 1.0 0.7991902072554992 12 Q13573,P61254 2 +Mitochondrial dna replication 0.4303399651875501 0.8541500148710378 0.3930218747318714 1.0 0.8002064296821275 10 Q14249,P49916,Q9UJZ1,Q96EY1,P54098 5 +Keratinocyte differentiation 0.3384905037825974 0.8536568659312804 0.3932951403655653 1.0 0.8002064296821275 24 Q13464,P04083,P11274,Q14980,O75116,Q13043,Q8NEY8,O75369,Q9P0M6,Q15648,Q8WX93,O75367,Q15149 13 +Regulation of dna metabolic process 0.3173224504791804 0.8531163889040048 0.3935947637825949 1.0 0.8002064296821275 150 Q8WVB6,Q15014,Q14249,O60832,Q9NPF5,P51608,Q99543,P20585,P18887,Q9UNS1,Q7Z3K3,Q96QC0,Q9HAF1,P16402,O60934,Q7Z4V5,Q9H981,Q86V81,P61088,Q9NYB0,Q92878,P53999,Q96QE3,P25490,P06748,P16403,P16104,P10412,P07305,P49750,Q9BRX5,P54132,Q92522,Q96T60,P09874,Q9H1E3,Q15906 37 +Negative regulation of cytokine production 0.3127789200091956 0.8522853076768341 0.394055758603077 1.0 0.8002064296821275 33 P04083,Q15910,P78540,Q9Y5K6,P15311,P14373,P20020,P30511,P08238,Q9UBC1,P25490 11 +Base excision repair 0.3497331431876019 0.8514482789677632 0.3945203826105525 1.0 0.8002064296821275 22 P49916,Q7Z6Z7,P18887,P39748,Q96T60 5 +Postsynaptic cytoskeleton organization 0.5627586206896497 0.8499921906297058 0.395329428033619 1.0 0.8002064296821275 5 Q9Y6W5,Q16352,Q9UJU6,P07196 4 +Clathrin dependent endocytosis 0.3546241000994728 0.849268223056275 0.3957320586272237 1.0 0.8002064296821275 21 Q2M2I8,O75146,Q9NZM3,P09496,O00291 5 +Regulation of mitotic cell cycle 0.3088366361658885 0.84857042200104 0.3961203712230459 1.0 0.8002064296821275 138 Q96ST3,P04083,P46013,Q96GD0,O60885,Q16513,P51608,O75150,Q13123,O75179,Q14676,Q9H7N4,Q15398,Q9UN37,Q13564,O75147,P12270,Q96QC0,O60934,Q9NZM5,Q13526,Q96QE3,O14745,Q7L2J0,Q9Y6D9,Q15910,Q01664,P61254,Q9UPT9,Q96EB6,Q99640,Q9NYL9,P54132,O00311,P54652,P78536 36 +Positive regulation of dephosphorylation 0.371461753467097 0.8484675070599239 0.396177660832036 1.0 0.8002064296821275 17 P26599,Q13464,P42345,Q13526,O14974,P08238,P0DP25,Q15435 8 +Metal ion export 0.4420517843068549 0.8474587720150316 0.3967394576701528 1.0 0.8009328081813814 9 P0DP25,P20020,P05026 3 +Signal transduction involved in regulation of gene expression 0.7006615214994563 0.8452172957322476 0.3979895273051643 1.0 0.802969785253495 2 P09874 1 +Pituitary gland development 0.7006615214994538 0.845217295732238 0.3979895273051697 1.0 0.802969785253495 2 O94788 1 +Positive regulation of bone mineralization 0.7226357871519139 0.8448118558870465 0.3982158940262965 1.0 0.803018068141938 3 O95747,P20020 2 +Meiotic spindle organization 0.4844639217666795 0.8440953176719842 0.3986161440026101 1.0 0.803018068141938 7 Q08379,P35579 2 +Regulation of stem cell proliferation 0.5149083392150141 0.8436360441503453 0.3988728162429114 1.0 0.8032922315025016 6 P26583 1 +Regulation of tumor necrosis factor mediated signaling pathway 0.4533408364878991 0.8422133388763462 0.399668548736352 1.0 0.8038725869283269 8 Q13049,P78536 2 +Rna polyadenylation 0.3102413069630209 0.8406182253753582 0.4005618452164574 1.0 0.8047874541875489 34 P11940,Q8N684,Q12849,Q5VTR2,Q8N7H5,Q6P1J9,P18615,O75150,Q9P2I0,P33240,O00267,Q6UN15,Q6PJT7,P09012,Q9C0J8,O94992 16 +Transcription elongation from rna polymerase i promoter 0.605238324189652 0.840364386974278 0.4007041105239515 1.0 0.8047907097710476 4 O15160 1 +Nucleobase containing compound transport 0.2909065289009115 0.8367148018283784 0.4027528970090741 1.0 0.8053754018535481 116 O75152,Q9UKX7,Q9Y6M1,Q8WYP5,Q8TD16,P49790,Q92945,Q9NZI8,P12270,Q6P6C2,P55735,Q9H814,Q96PU8,Q86V81,P35658,Q14008,P06748,Q9HAU5,Q9NPA8,Q9BY77,Q8NFH5,Q53F19,P82979,Q9H7Z3,Q9BZI7,P51991,O00159 27 +Regulation of myeloid leukocyte differentiation 0.4522967499683575 0.8366157460157293 0.4028085918607058 1.0 0.8053754018535481 8 P42345,Q04721,Q9UKV3 3 +Changes to dna methylation involved in embryo development 0.6984564498346135 0.8363555777116777 0.4029548953649398 1.0 0.8054261964960182 2 P26358 1 +Negative regulation of biomineralization 0.7199638751540997 0.8349148341249156 0.4037656619176852 1.0 0.8054977576193169 3 Q13464 1 +Chaperone cofactor dependent protein refolding 0.372601845747052 0.8344569848431679 0.4040235171756268 1.0 0.8054977576193169 16 P0DMV9,P54652,P25685,P61604,Q9NXW2 5 +Negative regulation of helicase activity 0.6036955322669615 0.8340806723675332 0.4042355256520173 1.0 0.8054977576193169 4 Q96EB6,P04637,P49736 3 +Cellular response to nutrient 0.4823009152717186 0.8332860399028387 0.4046834276121065 1.0 0.8054977576193169 7 Q13573,Q15648 2 +Mitotic g2 dna damage checkpoint signaling 0.4262347805102005 0.8304287041448372 0.4062964421892672 1.0 0.8059841272489925 10 Q9NZM5 1 +Regulation of connective tissue replacement 0.7187083145904772 0.8302719529887961 0.4063850417914452 1.0 0.8059841272489925 3 Q13464 1 +Positive regulation of tissue remodeling 0.7187083145904772 0.8302719529887961 0.4063850417914452 1.0 0.8059841272489925 3 Q13464 1 +Positive regulation of connective tissue replacement 0.7187083145904772 0.8302719529887961 0.4063850417914452 1.0 0.8059841272489925 3 Q13464 1 +Connective tissue replacement 0.7187083145904772 0.8302719529887961 0.4063850417914452 1.0 0.8059841272489925 3 Q13464 1 +Somatic diversification of immune receptors 0.3157099115313037 0.8297353095232431 0.4066884531689296 1.0 0.8059841272489925 27 P26583,O60934,P49916,P20585,Q96QE3 5 +Regulation of cytoplasmic transport 0.3873997856819823 0.8296786259131349 0.4067205092507828 1.0 0.8059841272489925 14 O60493,P35241,Q9Y3E7,P15311,Q9UMY4,O75165,P27361,P26038 8 +Hemidesmosome assembly 0.7185372339611369 0.8296397152519391 0.4067425151322594 1.0 0.8059841272489925 3 P11047 1 +Response to tumor cell 0.5574776158623554 0.8270092290909036 0.4082318304893499 1.0 0.8071067263125448 5 P10809,Q04721 2 +Rrna 5 end processing 0.5570914305042197 0.8253327395907158 0.4091827093424267 1.0 0.8080660363629644 5 P78316 1 +Ribonucleoprotein complex disassembly 0.556519669004456 0.8228517162860545 0.41059232299687 1.0 0.8095127938751026 5 P33176,Q07866,P55072 3 +Regulation of actin filament length 0.2917755717597321 0.8215870268704519 0.4113119752603968 1.0 0.8104585563989246 46 Q9Y281,P59998,P35241,Q96GD0,P42345,O75146,Q9UJU6,Q9UHB6,P35611,Q13813,Q9NYL9,Q01082,Q9UQB8,P62993,P47755,Q05655,Q14247,O00165 18 +Cellular response to reactive oxygen species 0.3067823628810222 0.8208758687062552 0.4117169776443123 1.0 0.8107769745984065 35 P00374,Q9NWH9 2 +Regulation of chromosome segregation 0.2986453082373979 0.8195363705575772 0.4124804599051868 1.0 0.8120404325911212 41 P12270,P46013,Q9Y6D9,Q14980,Q13123,Q15398 6 +Response to ether 0.5999179303402444 0.8187298411790566 0.4129405670748858 1.0 0.8127060732209422 4 Q6PKG0 1 +Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules 0.5996833965784574 0.8177784654083371 0.4134836965968982 1.0 0.8134973022663331 4 Q9BY67 1 +Regulation of axon guidance 0.5553079186670491 0.8175979207737578 0.4135868151870414 1.0 0.8134973022663331 5 O75592,Q9BVA1 2 +Actin filament severing 0.4789497919651196 0.8165856773632019 0.4141652428372233 1.0 0.8139777937906365 7 Q9Y281 1 +Regulation of dna duplex unwinding 0.5991568395320046 0.8156432423982968 0.4147042097287974 1.0 0.8143089026921421 4 Q04837,P49736 2 +Microtubule based transport 0.2823545667046266 0.8147439167911001 0.4152189093687073 1.0 0.8147830262781527 57 O14745,P46821,Q13409,Q9UPN4,P23246,Q14203,Q8TD16,Q9Y496,Q9Y366,Q14168,Q8NCM8,P11142,P33176 13 +Cardiac chamber morphogenesis 0.3972316859622403 0.8142653589283272 0.4154929501331097 1.0 0.8148407517770906 13 Q9P2D1,Q04721,Q96T37,Q15648 4 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.4232622901908558 0.8133240703733894 0.4160322800399809 1.0 0.815331799952953 10 Q13049 1 +Negative regulation of hematopoietic progenitor cell differentiation 0.6926681367144724 0.8131876216421854 0.4161104953227319 1.0 0.815331799952953 2 Q92785 1 +Positive regulation of excitatory postsynaptic potential 0.6923925027563331 0.812087886559821 0.41674120342882 1.0 0.8163275205065567 2 Q9UQB8 1 +Regulation of histone h3 k27 methylation 0.5981081526943708 0.8113937909080856 0.4171395637094761 1.0 0.8166276148787922 4 O75367,Q7KZ85 2 +Rhythmic process 0.2805057942133068 0.8102548163089432 0.417793738294467 1.0 0.8174278662313478 60 Q96ST3,P23246,P04083,Q15910,P42345,P11387,Q9Y2W1,Q8WXF1,O75592,Q96EB6,Q13185,Q7Z6Z7,Q9UNS1,Q9H2P0,Q9Y2K7,Q15233 16 +Neuron intrinsic apoptotic signaling pathway in response to oxidative stress 0.5977509663461757 0.8099473453715531 0.417970438993549 1.0 0.8175334893056441 4 P09874 1 +Dendrite development 0.2822919144991836 0.8095210199361697 0.4182155170870931 1.0 0.8177727545741751 56 P46821,Q8IZP0,Q12834,P51608,Q6SZW1,Q96HC4,Q9NZI8,Q13177,O75147,Q66K74,Q14444,Q9UJU6,Q15910,O43815,Q9UQB8,Q9ULH0,Q9UQ16,Q9BRT6,O96013,O60828,Q06787 21 +Renal tubule development 0.4470791849178178 0.8087393295473705 0.4186651005691111 1.0 0.8181253808998301 8 O95747,Q04721 2 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.4075320995120943 0.8065633733258978 0.4199180827266313 1.0 0.8191465215593984 12 P62942,Q9UNH7,Q13526,Q96EB6,Q9Y2U8,Q6YHK3,P50570,Q9UNE7,P78536 9 +Cop9 signalosome assembly 0.7118830989798709 0.8051243908671123 0.4207479020155555 1.0 0.8191465215593984 3 Q9UBW8,Q99627 2 +Aortic valve morphogenesis 0.7118261917683607 0.8049153814478603 0.4208685116848079 1.0 0.8191465215593984 3 Q13464 1 +Male gamete generation 0.2639239135128577 0.8038164795470258 0.4215029709230324 1.0 0.8195196939177404 89 Q9BY67,P16104,Q9UPN4,P26583,P82094,Q6P6C2,Q9H0H5,Q14141,Q9P0K7,P04920,P54652,Q96PU8,P25440,Q15019,Q9H8Y8,Q9C0J8,P25490 17 +Schwann cell development 0.4461329760361852 0.8037018298353091 0.4215691970963819 1.0 0.8195196939177404 8 Q8N3R9,P11047 2 +Somite development 0.4142119707148225 0.8013614862810027 0.4229224046929682 1.0 0.8211917983283458 11 Q7Z6E9 1 +Negative regulation of cell cell adhesion 0.3433336789907331 0.8003981421753322 0.4234801570558757 1.0 0.8214809019118258 22 P80404,P04083,Q9Y6D9,P78540,Q96IZ0,Q5JRA6,Q05655,P49593 8 +Regulation of cell substrate junction organization 0.3375529686861524 0.7972547759356984 0.4253030794403027 1.0 0.822897698376169 23 Q13464,P60903,P18206,Q9ULV4,Q15555,Q9H2G2,O75116,P49593 8 +Positive regulation of receptor clustering 0.6885336273428821 0.7967262173725863 0.4256100541380572 1.0 0.822897698376169 2 Q15334 1 +Regulation of dendrite development 0.331712032831988 0.7966509504913785 0.4256537779351963 1.0 0.822897698376169 24 O75147,Q15910,Q12834,Q6SZW1,Q9UQB8,O60828 6 +Positive regulation of natural killer cell mediated immunity 0.5942703805994898 0.7958778422853006 0.4261030412506605 1.0 0.8230497131956801 4 Q9BY67 1 +Positive regulation of natural killer cell mediated cytotoxicity 0.5942703805994898 0.7958778422853006 0.4261030412506605 1.0 0.8230497131956801 4 Q9BY67 1 +Cellular response to thyroid hormone stimulus 0.5940019739207053 0.7947948076642326 0.4267328718597178 1.0 0.8237422279483525 4 P35241,Q15648 2 +Negative regulation of homotypic cell cell adhesion 0.7082988695891899 0.7919824716083408 0.4283708968355677 1.0 0.8245079198455596 3 P80404,Q05655 2 +Postsynaptic actin cytoskeleton organization 0.5928885360835545 0.7903050567639863 0.4293496343394758 1.0 0.8252531055884559 4 Q9Y6W5,Q9UJU6 2 +Telomere maintenance in response to dna damage 0.5487944351223811 0.7894616273154478 0.4298422489012741 1.0 0.8257234896713633 5 P18887 1 +Positive regulation of g1 s transition of mitotic cell cycle 0.3684746962842398 0.7885674593187441 0.4303648562073812 1.0 0.82648909543199 15 Q7L2J0,P78536 2 +Ammonium transmembrane transport 0.6857772877618735 0.7857941378764092 0.4319881014784623 1.0 0.8269841184050334 2 P55011 1 +Animal organ formation 0.5474086362427084 0.7834990438116309 0.4333341149722116 1.0 0.8286732678786892 5 P27361,Q8NC56 2 +Isotype switching to igg isotypes 0.7054621586100793 0.78161420211442 0.4344413378772507 1.0 0.8295305352593131 3 Q96QE3 1 +Renal sodium ion transport 0.6846747519294654 0.7814310230337645 0.4345490308255897 1.0 0.8295305352593131 2 O14745 1 +Renal absorption 0.6846747519294654 0.7814310230337645 0.4345490308255897 1.0 0.8295305352593131 2 O14745 1 +Positive regulation of defense response 0.2846371515498425 0.7813611245071463 0.4345901289837064 1.0 0.8295305352593131 48 Q96ST3,Q9BY67,Q96PK6,P26583,Q7Z434,Q8WXF1,P43243,P30511,Q15648,P39019,O60828,Q9NZI8,Q15233 13 +Schwann cell differentiation 0.4299509334208802 0.7805597092854052 0.4350614965770099 1.0 0.8295305352593131 9 Q8N3R9,P11047 2 +Motor neuron axon guidance 0.4715221978942271 0.7797857516691942 0.4355169944310957 1.0 0.8301614354506323 7 P84095 1 +Regulation of actin cytoskeleton reorganization 0.4028732126736096 0.7784312744218347 0.4363148075979854 1.0 0.8308449639096365 12 Q9UQB8,Q04721,Q9Y5K6,Q07157 4 +Negative regulation of mitotic cell cycle phase transition 0.2895013040956728 0.7784001605173215 0.4363331441774476 1.0 0.8308449639096365 45 Q13564,P12270,Q15910,Q9Y6D9,P61254,O60934,Q9NZM5,Q13123,Q9UN37 9 +Positive regulation of signal transduction by p53 class mediator 0.4101677347558202 0.7776357227171014 0.4367837952391733 1.0 0.8309119485674964 11 P62081,P62841,P61254 3 +Crd mediated mrna stabilization 0.4403326991388669 0.7729504870558621 0.4395516838602438 1.0 0.8339716493358037 8 P11940,Q9NZI8,Q00839 3 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4403326991388669 0.7729504870558621 0.4395516838602438 1.0 0.8339716493358037 8 P11940,Q9NZI8,Q00839 3 +Wound healing spreading of epidermal cells 0.4996936823353679 0.7727715533073988 0.4396575914782188 1.0 0.8339716493358037 6 P42345,P78536 2 +Peptidyl lysine dimethylation 0.681642778390291 0.7694617747840754 0.4416192283891029 1.0 0.8361384090613694 2 Q12824 1 +Spindle elongation 0.4691586068734519 0.7681421763307189 0.4424027221872364 1.0 0.836585206521433 7 Q9H0H5,Q14980 2 +Positive regulation of oxidative stress induced cell death 0.4986910788687196 0.7681414821102408 0.4424031345804575 1.0 0.836585206521433 6 P23246,Q14249 2 +Regulation of cell cycle 0.3457632505402701 0.7676733699701589 0.4426812609616237 1.0 0.8367363621659664 299 Q96ST3,Q9UPN4,P46013,Q12834,Q8WYP5,Q96GD0,O75150,Q14676,Q13049,Q9UN37,Q13564,Q9NZM5,O75528,Q9H981,P43487,P25490,P06748,P0DMV9,Q7L2J0,Q9Y6D9,P23246,Q14980,Q9UNZ2,P54132,Q13769,Q92733,Q15906,Q15014,P04083,Q9UQN3,O60885,P51608,Q9HD42,Q9UIG0,O75147,P12270,O75400,O60934,Q02241,Q9BV73,Q16543,Q9NZZ3,P35658,Q9H444,Q15910,P11274,P61254,Q99459,Q96EB6,Q99640,Q9NYL9,Q9ULW0,Q9Y6G9,P78536,O75116,O94992,P11142,Q9Y3E7,Q9NPF5,Q9H0H5,O75179,P46940,Q15648,Q9H7N4,P11802,Q13243,Q96DE0,Q9HAF1,Q9Y448,Q96QE3,O14745,P16104,Q96PK6,O00311,P54652,Q9NQG5,Q16513,P18583,Q13123,Q9UNS1,Q15398,P39748,Q96QC0,Q13526,Q7Z7K6,Q14203,Q01664,Q9UPT9,Q99496,O95785,Q9Y6A5,P51610 92 +Response to bacterium 0.2750269612345559 0.7666994572183707 0.4432602264422856 1.0 0.8372553525825083 63 O60493,Q9P2D1,P26583,P82094,P11274,Q7Z434,P78540,Q04721,Q13151,Q9UQB8,Q96JM3,O75179,P78536,P39019,Q9UBC1,Q9NZZ3,Q96EE3,Q02952 18 +Modified amino acid transport 0.4387495845241397 0.7645975191606404 0.4445112468834558 1.0 0.8381096864935687 8 O43772 1 +Positive regulation of myeloid cell apoptotic process 0.70030328094844 0.7628355856621799 0.4455614555683724 1.0 0.8396974305506356 3 P04083,Q96EB6 2 +Interleukin 17 production 0.7000986188005697 0.7620927159277993 0.4460046699358952 1.0 0.8397718638215785 3 P78540 1 +Regulation of maintenance of sister chromatid cohesion 0.5852178709321583 0.7595120127416821 0.4475463308119938 1.0 0.84164462982709 4 O75367,Q8IY18,P41227 3 +Endothelial cell migration 0.2947937249338127 0.7590481187130097 0.4478237727486762 1.0 0.841817712768533 39 P04083,Q9NWH9,Q4VCS5,P51608,Q96EB6,Q5JRA6,P67870,P78536,Q13630,P35579 10 +Regulation of natural killer cell mediated immunity 0.4372571140068786 0.756739392570543 0.4492060094696395 1.0 0.8437018424264839 8 Q9BY67 1 +Regulation of histone h3 k36 methylation 0.5844016285891965 0.7562500051150406 0.4494993168229659 1.0 0.8437769649688923 4 Q96L73 1 +Ventral spinal cord development 0.4960012605031783 0.7557463518317621 0.4498012875617494 1.0 0.8438993536066678 6 Q8NCM8 1 +Cellular response to atp 0.6777839029768541 0.7542920913219663 0.4506738501681686 1.0 0.8446088480930555 2 Q96GD0 1 +Rna decapping 0.4251383560189507 0.7542432688908877 0.4507031604579423 1.0 0.8446088480930555 9 Q8IZD4,Q6P2E9 2 +Vesicle fusion to plasma membrane 0.6975461814171467 0.7528419389354133 0.4515449015008119 1.0 0.84556215586291 3 O95721,Q12846 2 +Cellular response to ether 0.6973770158020602 0.7522297514604386 0.451912904875579 1.0 0.84556215586291 3 Q6PKG0 1 +Protection from non homologous end joining at telomere 0.6969782386588668 0.7507870871116965 0.4527808019090975 1.0 0.8465971659608216 3 P18887 1 +Homotypic cell cell adhesion 0.3462617837858528 0.7500568093421396 0.4532204906438117 1.0 0.8470399996082525 20 P80404,P35241,P18206,Q9UDY2,P21333,P35579,Q05655,P12814,Q9Y490 9 +Negative regulation of peptidyl threonine phosphorylation 0.6766813671444252 0.7499713997642011 0.4532719301416121 1.0 0.8470399996082525 2 P0DP25 1 +Positive regulation of immune response 0.2532116142479089 0.7490089560294776 0.4538518074095132 1.0 0.8471848042172989 82 Q96ST3,Q9BY67,P04083,P30511,Q15648,Q9NZI8,Q15233,Q13177,P15311,P61088,Q96QE3,P51809,Q12846,P23246,Q96IZ0,Q8WXF1,Q96EB6,P39019,Q7Z434,Q96PK6,P26583,P43243,O60828,O94992 24 +Positive regulation of chemotaxis 0.341561653832363 0.7482944568383184 0.4542825672906683 1.0 0.8472663212334466 21 Q9NWH9,P78536 2 +Positive regulation of endothelial cell apoptotic process 0.6959699286456933 0.7471421753599101 0.4549777442515674 1.0 0.8472663212334466 3 Q53EL6 1 +Cellular aldehyde metabolic process 0.3257162931781329 0.7468979952126642 0.455125136207263 1.0 0.8472663212334466 24 P29401,Q96GD0,O75874,O94788,P48735,Q6UX07 6 +Negative regulation of organelle organization 0.2881975578142765 0.7468178057122337 0.4551735460364012 1.0 0.8472663212334466 120 P46821,Q8WWK9,Q9NWH9,Q9Y3E1,Q13123,P35611,Q7Z6Z7,P18887,Q92974,O15344,Q13136,Q9UIG0,Q07157,P12270,O60934,P16949,O75146,Q13813,Q9NYB0,Q92878,P06748,Q9H444,Q9Y6D9,P27816,Q9UHB6,P02545,Q9NYL9,Q9ULW0,Q01082,Q9Y6G9,Q96PK6,P09874,P47755 33 +Cytokine production involved in immune response 0.3620965243036039 0.7455797737841918 0.4559213048954671 1.0 0.8481842315592297 15 Q96EB6,Q92499,P30511,Q7Z434,Q9NR30 5 +Dna methylation dependent heterochromatin assembly 0.4111905422889336 0.7445543979562698 0.4565411444319385 1.0 0.848851376618689 10 Q9NRZ9,P26358,Q96EB6,Q8NEY8,O95983 5 +Positive regulation of cellular response to insulin stimulus 0.4643015943355517 0.7443245735366316 0.456680138213744 1.0 0.848851376618689 7 O00159,Q9H1E3 2 +Cell differentiation involved in embryonic placenta development 0.6945133719327242 0.7418842448587054 0.4581574723275263 1.0 0.8504444359559712 3 Q13043,O75190 2 +Estrous cycle 0.6942929268566664 0.7410892362380649 0.4586393355487881 1.0 0.8511017419014001 3 Q9H2P0 1 +Histone h3 k9 modification 0.3848603369195861 0.7371281578288705 0.4610444171467907 1.0 0.8524779092511572 13 P26358,P02545,P51608 3 +Response to leukemia inhibitory factor 0.2979361372969973 0.7340284668595874 0.462931388633762 1.0 0.8545438933438966 35 P23378,Q8NFH5,Q9NRZ9,O60264,P19338,O14678,Q16352,P84103,Q96EB6,P13010,Q9NYF8,Q9P015,P32929,P31153,Q00839,P26367 16 +Production of molecular mediator of immune response 0.2903947882994336 0.7331178309827548 0.4634865656273241 1.0 0.8553317175094829 41 Q12846,O60934,Q8WYA6,Q96EB6,Q96QE3,Q92499,P30511,P20585,Q7Z434,Q9NR30,P25490 11 +Regulation of gtp binding 0.461864533728484 0.7324318599790507 0.4639050185987032 1.0 0.8555462817039782 7 Q9NWH9 1 +Retrograde axonal transport 0.4210937569699224 0.7322696141279665 0.4640040218439574 1.0 0.8555462817039782 9 P33176 1 +Glutamate secretion 0.671995589856672 0.731677592491759 0.4643653762259814 1.0 0.855712475407578 2 Q15042 1 +Regulation of myeloid cell apoptotic process 0.461676668840983 0.7315167600317793 0.4644635711608829 1.0 0.855712475407578 7 P42771,P04083,Q7L5Y9,Q96EB6,P78536 5 +Blood vessel remodeling 0.534784845076119 0.7296022494736125 0.4656333468221452 1.0 0.8565801483936318 5 Q9P2D1,P21333 2 +Epithelial cell proliferation 0.2761419344559973 0.7284550047564886 0.4663351027767231 1.0 0.8565801483936318 53 Q9UII2,P26583,Q86VI3,P11047,Q9Y366,O95747,Q15648,P58107,P78536,P07942 10 +Epithelial tube formation 0.3234178703531158 0.7280123472512062 0.4666060279976718 1.0 0.8565801483936318 24 Q13308,Q9Y366,O95747,P62081,P25440,O95487,O15078 7 +Ornithine metabolic process 0.6708930540242486 0.7273898044466551 0.4669871984285203 1.0 0.8570437233969153 2 P78540 1 +Positive regulation of cytoplasmic translation 0.4079572688845254 0.7263458381852979 0.4676267854328484 1.0 0.8577449461876752 10 O60506,P11940,P14618,Q9NZI8,Q00839,Q14103 6 +Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.4196387213661607 0.7243984675628501 0.4688211403917774 1.0 0.8588882277172378 9 P78316,Q86U38,Q8N9T8,Q15050 4 +Cardiac conduction system development 0.6891062291954406 0.7224431139640343 0.470022087854111 1.0 0.8598811384699907 3 Q04721 1 +T cell homeostasis 0.5330289331738235 0.72216941201752 0.4701903267897549 1.0 0.8598811384699907 5 P62753 1 +Activation induced cell death of t cells 0.5330289331738235 0.72216941201752 0.4701903267897549 1.0 0.8598811384699907 5 P62753 1 +Regulation of nucleocytoplasmic transport 0.2754759855929135 0.7204003983526286 0.4712785048217172 1.0 0.8606516993208004 51 P12270,Q9NPF5,O14974,Q9H7Z3,Q14978,P49790,P21333,P35658 8 +5s class rrna transcription by rna polymerase iii 0.5325047881385729 0.7199539069905012 0.4715533756115597 1.0 0.8606780702114909 5 Q9Y5Q8 1 +Protein modification by small protein removal 0.2754552484624418 0.7199020536245131 0.4715853035151855 1.0 0.8606780702114909 52 Q9UPT9,Q9UBW8,Q04323,Q9NZM5,O75528,Q99496,Q9NPA8,P51784,P55072,P40818 10 +Ventricular septum development 0.4589445726278048 0.7182362909117198 0.4726116049077753 1.0 0.861197623603829 7 Q13308,P43243 2 +Kinetochore organization 0.4296337276669597 0.7168665404121994 0.4734564493154471 1.0 0.8612708896686709 8 O95347,Q9H3R5,Q7Z3K3,Q15398 4 +Response to dexamethasone 0.4059838376555863 0.7152803153803063 0.4744358494706877 1.0 0.8612708896686709 10 Q9H7B4,P40818,Q13185 3 +Positive regulation of cellular response to transforming growth factor beta stimulus 0.5310852254032672 0.7139611135186501 0.4752512255155448 1.0 0.8612708896686709 5 Q13573 1 +Histone h2b ubiquitination 0.4867628027786714 0.7134875904613481 0.4755440894238569 1.0 0.8612708896686709 6 Q8N7H5,Q6P1J9,O75150 3 +Regulation of transcription regulatory region dna binding 0.3919382199380785 0.7132126738619002 0.4757141648832275 1.0 0.8612708896686709 12 P07305,P09874,Q96L73 3 +Positive regulation of actin filament depolymerization 0.573421727681858 0.7126671189426498 0.4760517678229607 1.0 0.8612708896686709 4 Q9Y281 1 +Negative regulation of actin nucleation 0.6863280736869158 0.7125035056837378 0.476153041365587 1.0 0.8612708896686709 3 O75146 1 +Negative regulation of arp2 3 complex mediated actin nucleation 0.6863280736869158 0.7125035056837378 0.476153041365587 1.0 0.8612708896686709 3 O75146 1 +Negative regulation of cd4 positive alpha beta t cell differentiation 0.6667585446526975 0.7113688846442975 0.4768556752993771 1.0 0.8612708896686709 2 P04083 1 +Negative regulation of alpha beta t cell differentiation 0.6667585446526975 0.7113688846442975 0.4768556752993771 1.0 0.8612708896686709 2 P04083 1 +Neutrophil clearance 0.6667585446526975 0.7113688846442975 0.4768556752993771 1.0 0.8612708896686709 2 P04083 1 +Regulation of cd4 positive alpha beta t cell differentiation 0.6667585446526975 0.7113688846442975 0.4768556752993771 1.0 0.8612708896686709 2 P04083 1 +Myeloid dendritic cell activation 0.666758544652694 0.7113688846442835 0.4768556752993858 1.0 0.8612708896686709 2 Q04721 1 +Regulation of t cell mediated immune response to tumor cell 0.6667585446526938 0.711368884644282 0.4768556752993866 1.0 0.8612708896686709 2 P10809 1 +Regulation of response to tumor cell 0.6667585446526938 0.711368884644282 0.4768556752993866 1.0 0.8612708896686709 2 P10809 1 +Trna transcription 0.4859543436325715 0.709814022576965 0.4778194722193729 1.0 0.8612708896686709 6 Q9Y5Q8 1 +Dna methylation 0.3407935861353953 0.7095527404588601 0.4779815350544343 1.0 0.8612708896686709 20 Q9NRZ9,Q15910,P09874,Q9NPF5,P26358,P51608,Q86YP4,O94776 8 +Sodium ion transport 0.3152626241229905 0.7092125009386345 0.4781926170440806 1.0 0.8612708896686709 25 P55011,P46939,O14745,P05026 4 +Synapse organization 0.2624648079419697 0.7084944471283302 0.4786382593046419 1.0 0.8612708896686709 71 Q12834,P51608,P10586,Q13136,Q96HC4,O75147,Q13526,Q14444,P19022,Q14247,Q14203,P11047,Q96EY1,Q9H2P0,O95793,P55072,Q9UQB8,P21333,P11142 19 +Methylguanosine cap decapping 0.4280023097814315 0.7083946865301943 0.4787001911859283 1.0 0.8612708896686709 8 Q6P2E9 1 +Positive regulation of interleukin 8 production 0.4568491671954726 0.7080867138477983 0.4788914097878374 1.0 0.8612708896686709 7 Q7Z434 1 +Response to corticosteroid 0.3012683831167692 0.7078047792847052 0.4790664980240713 1.0 0.8612708896686709 29 Q01664,P04083,P09874,O75592,Q13185,P20020,Q9H7B4,P61353,P40818 9 +Positive regulation of erythrocyte differentiation 0.3909722152902639 0.7075113711421958 0.479248748737862 1.0 0.8612708896686709 12 P0DMV9,P26583,Q15648 3 +Specification of symmetry 0.4045580493654598 0.7073090689780228 0.4793744309353696 1.0 0.8612708896686709 10 Q8NCM8,Q9Y366,O94788 3 +Physiological cardiac muscle hypertrophy 0.456587182950323 0.7068199839807575 0.4796783540670071 1.0 0.8613467938962985 7 Q12802,Q96HC4 2 +Regulation of voltage gated calcium channel activity 0.4852500056760607 0.7066169445488475 0.4798045560115827 1.0 0.8613467938962985 6 Q09666,O75323,P0DP25 3 +Keratinocyte proliferation 0.426356667683185 0.6998719792351303 0.4840072580031409 1.0 0.8640022381610194 8 Q15648,P58107 2 +Regulation of keratinocyte proliferation 0.426356667683185 0.6998719792351303 0.4840072580031409 1.0 0.8640022381610194 8 Q15648,P58107 2 +Mononuclear cell differentiation 0.2754310661329419 0.6985399935461869 0.4848395557210803 1.0 0.8650835022864632 49 Q9P2D1,P04083,Q15910,Q9UKV3,P42345,P25490,Q96EY1,O15347,Q15648,P78536,Q13769,P35579,O43290,P62753 14 +Tube formation 0.3077855288023319 0.6984870072281811 0.4848726805070029 1.0 0.8650835022864632 26 Q13308,Q9Y366,O95747,P62081,P25440,O15078 6 +Regulation of smad protein signal transduction 0.682223061868076 0.69788011333712 0.4852521721078928 1.0 0.8652971013337211 3 P09874 1 +Neuron projection extension 0.2885997182989438 0.6964200212639173 0.4861658282331431 1.0 0.8656895698335949 39 Q96ST3,P46821,Q13740,O60271,Q9UJU6,P11047,Q9NZM3,Q9BRT6,P46940,P08238,Q9H2P0,Q14247,P18206 13 +Stress granule disassembly 0.6817564767634039 0.6962228801420116 0.4862892610101692 1.0 0.8656895698335949 3 P33176 1 +Regulation of attachment of spindle microtubules to kinetochore 0.4540824414732035 0.6947350501183267 0.4872213581921283 1.0 0.8656895698335949 7 Q9H0H5 1 +Developmental growth involved in morphogenesis 0.2768383303086493 0.693718606035922 0.4878586953477675 1.0 0.8656895698335949 48 Q96ST3,P46821,Q13740,Q13308,O60271,Q9UJU6,P11047,Q9NZM3,Q9BRT6,P46940,Q15648,P53990,P08238,Q9H2P0,Q14247,P18206 16 +Mitotic chromosome condensation 0.3884658790090802 0.6927684252494736 0.4884548902375181 1.0 0.865920465500309 12 Q9HD42,O95347,Q9NTJ3,Q9UIG0 4 +Cellular extravasation 0.4132866947074145 0.6902596897542437 0.4900308926214702 1.0 0.8672273970647724 9 Q13464,P11274 2 +Regulation of megakaryocyte differentiation 0.41325308417472 0.6900800559131076 0.4901438445122923 1.0 0.8672273970647724 9 P62805,P26583,Q96T37 3 +Regulation of histone phosphorylation 0.4529920529949209 0.6894889959767686 0.4905155956779747 1.0 0.8672273970647724 7 P27361,O75367,Q06787 3 +Regulation of substrate adhesion dependent cell spreading 0.3379501385041749 0.6887025708172704 0.4910104580541852 1.0 0.8672273970647724 20 P46108,Q96AC1,O15144,P07237,P27797,Q9ULV4,P50570,Q92766,Q07021,Q13418,Q14185,P46109,O43707,P63000,P60903,P60953,Q14155,Q9P258,P21333 19 +Early endosome to golgi transport 0.4241308913618145 0.688382563917178 0.4912119009145783 1.0 0.8672273970647724 8 Q9Y5X2 1 +Positive regulation of muscle hypertrophy 0.4127626910724752 0.687460361085166 0.4917926715190548 1.0 0.8672273970647724 9 Q13464,P09874 2 +Gland morphogenesis 0.3766508325637708 0.686868763776534 0.4921654324406428 1.0 0.8672273970647724 13 Q04721,P15311,Q15648,P26038,O14745 5 +Cell division 0.3379200128746831 0.6840508414529237 0.4939430619673135 1.0 0.8672273970647724 221 Q13464,Q9NRZ9,Q8WWK9,Q8NBT2,Q9UQN3,Q96GD0,Q8WYP5,Q12834,P11387,Q9Y3E7,Q9BRX2,Q9H0H5,Q9UHD8,Q16513,P18583,Q96N67,Q96CS2,Q7Z4H7,Q9UNS1,Q92974,Q9HD42,Q9UN37,P40818,Q7Z3K3,Q9Y448,P12270,O75400,O75528,Q13526,Q02241,Q9Y5K6,Q14141,P16949,P09496,Q9H981,Q7Z7K6,Q9NZZ3,Q14008,Q9NQS7,Q01085,Q9H444,Q9Y6D9,Q14203,O43491,Q9UQE7,P27816,Q14980,P54132,Q01082,Q9ULW0,Q9Y6G9,Q96CT7,P35579,Q15149,P35580,Q15019,Q9Y6A5,Q13432,P51956,O00311,P49916,Q9HC35,Q9H7Z3,P53990,O75116,Q08379,O95347,Q96EE3,Q14683 69 +Positive regulation of chemokine c c motif ligand 5 production 0.6593164277839199 0.6827726902331802 0.4947504890439733 1.0 0.8672273970647724 2 Q7Z434 1 +Negative regulation of hormone secretion 0.4118243840368464 0.6824544408890167 0.4949516415148021 1.0 0.8672273970647724 9 Q6WKZ4,Q8N183 2 +Morphogenesis of a branching structure 0.344402779076844 0.6811026068329169 0.4958065677052974 1.0 0.8672273970647724 18 Q96T37,Q9UNS1,Q9NWH9,Q15648 4 +Positive regulation of nf kappab transcription factor activity 0.295881944720068 0.6805727396327562 0.4961418809258924 1.0 0.8672273970647724 32 P06748,P0DMV9,O60858,P14373,P61088,Q13049,Q92974 7 +Secretory granule localization 0.6584895259096155 0.6796152521927776 0.4967481096265138 1.0 0.8672273970647724 2 P33176 1 +Cell differentiation involved in phenotypic switching 0.6582138919514806 0.6785636814480013 0.4974143614039499 1.0 0.8672273970647724 2 P26358 1 +Phenotypic switching 0.6582138919514806 0.6785636814480013 0.4974143614039499 1.0 0.8672273970647724 2 P26358 1 +Positive regulation of vascular associated smooth muscle cell differentiation 0.6582138919514806 0.6785636814480013 0.4974143614039499 1.0 0.8672273970647724 2 P32929 1 +Reversible differentiation 0.6582138919514806 0.6785636814480013 0.4974143614039499 1.0 0.8672273970647724 2 P26358 1 +Response to l ascorbic acid 0.6582138919514808 0.6785636814480013 0.4974143614039499 1.0 0.8672273970647724 2 P17301 1 +Transforming growth factor beta activation 0.657938257993377 0.6775125669110134 0.4980807994076306 1.0 0.8672273970647724 2 P08238 1 +Regulation of transforming growth factor beta activation 0.657938257993377 0.6775125669110134 0.4980807994076306 1.0 0.8672273970647724 2 P08238 1 +Anion homeostasis 0.5217092422831124 0.6746694847786131 0.4998857760451312 1.0 0.8672273970647724 5 O14745 1 +Ameboidal type cell migration 0.2512041609736117 0.6735696220672395 0.5005849717468243 1.0 0.8672273970647724 85 Q13464,P04083,Q9NWH9,Q16513,P51608,P46940,Q9ULV4,Q4VCS5,Q15555,P19022,Q5JRA6,Q7Z7K6,Q96EB6,P58107,P35579,Q15149,O94776,P42345,P67870,P78536,O75116,Q13630,Q02952 23 +Telomere maintenance via semi conservative replication 0.521436440676549 0.6735341363395411 0.5006075390739833 1.0 0.8672273970647724 5 P39748 1 +Negative regulation of camp dependent protein kinase activity 0.6753183458027345 0.6734611714982124 0.500653943126856 1.0 0.8672273970647724 3 Q96EB6 1 +Rrna pseudouridine synthesis 0.5212961605788049 0.6729504971983964 0.500978784702087 1.0 0.8675066765356951 5 Q9NPE3 1 +Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.4770788350163156 0.6697665094811549 0.503006646032043 1.0 0.8688240553562351 6 P78316 1 +Regulation of toll like receptor 3 signaling pathway 0.5624608669802762 0.6697608342614035 0.5030102644114378 1.0 0.8688240553562351 4 Q9UMX0 1 +Regulation of embryonic development 0.3391081530660643 0.6691885495365052 0.5033752095717641 1.0 0.8692290425523825 19 O95747,Q9H0H5,Q4VCS5 3 +Protein localization to cell periphery 0.263415213925094 0.6670500250091548 0.504740180279518 1.0 0.8713380449345931 98 Q13464,Q9Y2J2,O75915,Q9NQ48,Q13136,Q9UN37,P33176,O15027,P15311,P19022,Q8IWJ2,O14745,P84095,O43491,Q14980,Q9H4M9,Q01082,P05026,Q9H8Y8,P55196,Q13356,Q5EBL8,P21333,Q8N3R9 24 +Regulation of chromatin assembly or disassembly 0.3731053860075728 0.6654257203414238 0.5057782385933063 1.0 0.8726999807067097 13 Q96ST3,P12270,Q66K74,P26358,Q8NEY8,O75367 6 +Positive regulation of chromatin organization 0.4191665146283783 0.6629199181983784 0.5073818442580125 1.0 0.8730012810658605 8 Q96ST3,P26358,Q8NEY8,P12270 4 +Regulation of homotypic cell cell adhesion 0.5184317765592289 0.6610602163409338 0.5085736973606432 1.0 0.8730012810658605 5 P80404,P35241,Q05655 3 +Regulation of cell division 0.2855293092882581 0.6591315124695988 0.5098113214601339 1.0 0.8744498000945963 38 O75400,Q16513,Q8WYP5,Q96GD0,Q9H0H5,O75528,Q13526,P54132,Q7Z7K6,Q9UN37 10 +Regulation of intracellular transport 0.2915011345071302 0.658737471393812 0.5100643662399778 1.0 0.8745479986758994 132 Q9UPN4,Q9Y3E7,Q9NPF5,Q7Z6Z7,P49790,Q9BRK0,O15078,Q9UII2,O60493,P12270,Q8NBM4,P15311,O14974,P35658,Q8IWJ2,P49257,Q14980,Q99496,Q07960,Q9GZY8,Q9H7Z3,Q14978,O00159,P21333 24 +Embryonic viscerocranium morphogenesis 0.6706148685808169 0.656960946210767 0.511206028238363 1.0 0.8757147236112046 3 Q6UB35 1 +T cell migration 0.3953460277308995 0.6563148333443285 0.5116215754287088 1.0 0.8759254948030715 10 P55011,O95747,P78536,P26038,Q15149 5 +Positive regulation of stress fiber assembly 0.3484340250544711 0.6553859407783251 0.5122193010665745 1.0 0.8765489297984895 15 P42345,O75116,P60903,O60504 4 +Negative regulation of microtubule polymerization or depolymerization 0.3437021050552619 0.6550581015309832 0.5124303466372613 1.0 0.876684891961334 17 P46821,Q8WWK9,Q9Y3E1,P16949,Q9ULW0,Q92974 6 +Regulation of heterotypic cell cell adhesion 0.5584666298952033 0.6542893412528888 0.5129254115948714 1.0 0.8773065704865296 4 Q14254,Q9H4A3,O75955 3 +Negative regulation of cellular protein catabolic process 0.2928363365692612 0.6526310484665511 0.5139941641155146 1.0 0.8774283538064538 32 Q04323,Q9NZM5,P62081,P62913 4 +Transcription initiation from rna polymerase ii promoter 0.308319283382193 0.6516309463602297 0.5146392791084984 1.0 0.8774283538064538 25 P35269,P29083,Q14241,P13984,P53999,Q9NVC6,Q15648,P11802 8 +Regulation of mrna 3 end processing 0.3365972566128444 0.651444122856875 0.5147598360766374 1.0 0.8774283538064538 19 Q8N684,Q8N7H5,Q5VTR2,P18615,Q6P1J9,O75150,O00267,Q6PJT7,P09012 9 +Cardiac muscle tissue development 0.2891278379232907 0.6498971871026276 0.5157586352788841 1.0 0.8774283538064538 35 Q9P2D1,Q12802,O75147,P42345,Q15149,P02545,Q15648,O94788,Q96HC4,P25490 10 +Dna damage response signal transduction resulting in transcription 0.51550820515221 0.6489786706616985 0.5163521628211862 1.0 0.8782073292608483 5 P61254 1 +Positive regulation of protein localization to nucleus 0.2844249623012295 0.6483717721573498 0.516744523076127 1.0 0.8786503350518524 38 Q7L2J0,P12270,Q9NPF5,Q9Y5K6,Q7Z434,P21333 6 +Response to vitamin a 0.6680452164323103 0.64799413877146 0.516988741234718 1.0 0.8788412845383239 3 P46821,O94788 2 +Mechanoreceptor differentiation 0.4050082783964396 0.6463588980172421 0.5180469524008298 1.0 0.879212683239432 9 Q9UM54,O14745 2 +Positive regulation of release of cytochrome c from mitochondria 0.4717336352522802 0.6459143022730649 0.5183348566102894 1.0 0.879212683239432 6 Q9GZY8 1 +T cell mediated immunity 0.3803552856331776 0.6455790332615697 0.5185520194518656 1.0 0.879212683239432 12 Q9BY67 1 +Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.3319970832745222 0.645564082912408 0.5185617042938759 1.0 0.879212683239432 20 Q14137,Q8IY81,Q15050,P78316,Q8N9T8,Q86U38 6 +Regulation of neural precursor cell proliferation 0.3803108917741321 0.6453230471447183 0.5187178602590017 1.0 0.879212683239432 12 P48681 1 +Hippo signaling 0.4715187437193989 0.6449598189183706 0.5189532249691693 1.0 0.879212683239432 6 Q13043,Q4VCS5,Q01085 3 +Regulation of cd4 positive alpha beta t cell activation 0.6669423766197932 0.6441563789827592 0.5194740340302417 1.0 0.879212683239432 3 P04083,P78540 2 +Negative regulation of cd4 positive alpha beta t cell activation 0.6669423766197932 0.6441563789827592 0.5194740340302417 1.0 0.879212683239432 3 P04083,P78540 2 +T helper 1 type immune response 0.6669423766197933 0.6441563789827581 0.5194740340302424 1.0 0.879212683239432 3 P42345,P04083 2 +T helper 1 cell differentiation 0.6669423766197933 0.6441563789827581 0.5194740340302424 1.0 0.879212683239432 3 P42345,P04083 2 +Negative regulation of t cell proliferation 0.443429359772599 0.6438916164097979 0.5196457185601215 1.0 0.879212683239432 7 Q9Y6D9,P78540 2 +Heart development 0.2617848479515052 0.6435817209107053 0.519846706586629 1.0 0.879212683239432 98 Q13464,Q8NC56,O95747,Q15648,Q96HC4,Q9P2D1,Q12802,O75147,Q04721,Q9BQ70,O75592,Q13043,P80723,O95487,P25490,P13807,Q96T37,Q13308,P02545,Q15149,Q9NR12,P42345,P43243,Q9Y366,O94788,O75116,P21333,Q8NCM8,O94992 29 +Muscle cell migration 0.3580568859884973 0.6418761352097264 0.5209536105656176 1.0 0.8802052081893379 14 Q13464,P04083,P46108,Q96N67,Q9NVD7 5 +Negative regulation of cell killing 0.4706550812484268 0.6411272440781836 0.5214400148047342 1.0 0.8805661289300734 6 P08238,P30511,P46108 3 +Hormone mediated signaling pathway 0.2735926030291435 0.6399415781531983 0.5222105815713605 1.0 0.8816439164795751 47 Q9UER7,Q15424,P82094,P09874,O75528,Q9NS86,Q14151,Q96EB6,Q8TDD1,Q15648,Q9GZZ9 11 +Regulation of plasma membrane organization 0.5544467592209524 0.6388130084227172 0.5229445847353049 1.0 0.8822449720459877 4 P35579,P50570 2 +Regulation of mitotic nuclear division 0.2819789775771565 0.6385798189181511 0.5230963133565973 1.0 0.8822449720459877 40 O75147,P12270,P46013,Q9Y6D9,Q96GD0,Q13526,Q99640,Q13123,Q15398 9 +Ventricular cardiac muscle tissue development 0.4421483739034545 0.6378425355392191 0.5235761876602163 1.0 0.88227434557024 7 Q9P2D1 1 +Bone cell development 0.4140007570343146 0.6366783422259212 0.5243343836178611 1.0 0.8823426330093275 8 Q04721,Q8IZP0,Q15648 3 +Positive regulation of growth 0.2671928936206658 0.6363697472922203 0.5245354543481149 1.0 0.8823426330093275 58 Q9P2D1,P15311,Q9NZM3,Q7Z4V5,Q9NXV6,P78536,Q13049,Q9H2P0 8 +Regulation of protein dephosphorylation 0.2931742863634119 0.6354585137882343 0.5251294157971103 1.0 0.8823426330093275 29 P62942,P26599,Q13464,P42345,Q13526,Q12972,O14974,O75116,P67870,P08238,P0DP25,Q15435 12 +Homeostasis of number of cells 0.2621825535541128 0.6354372705009369 0.5251432667300289 1.0 0.8823426330093275 66 P04083,Q14157,Q15648,Q9H9B4,Q9UII2,P19022,P62753,P0DMV9,Q15910,P11274,Q9UKV3,Q99496,Q96EY1,Q9NYL9,P39019,Q9GZZ9,P62263,P26583,P78536 19 +Positive regulation of embryonic development 0.4137061181061442 0.6351897950943871 0.5253046380771509 1.0 0.8823426330093275 8 O95747,Q4VCS5 2 +Negative regulation of establishment of protein localization 0.2907588781869106 0.6337508001448487 0.5262434662882605 1.0 0.8827962373010345 32 O60493,P49257,O00233,Q8NBM4,P30040,P31689,Q6WKZ4,Q8N183 8 +Regulation of exosomal secretion 0.3911874471398162 0.6336053092202192 0.5263384350885183 1.0 0.8827962373010345 10 O14964,Q9Y3E7 2 +Histone ubiquitination 0.3261217354173984 0.6328089046940266 0.5268584410453019 1.0 0.8830014928915223 21 Q9UPT9,Q8N7H5,Q99496,Q6P1J9,O75150,Q7Z6Z7,Q13620,P61088,O95071 9 +T cell differentiation involved in immune response 0.5525446706335893 0.6315242047211735 0.527697828005014 1.0 0.8835927235674561 4 P42345 1 +Cd4 positive alpha beta t cell differentiation 0.5525446706335893 0.6315242047211735 0.527697828005014 1.0 0.8835927235674561 4 P42345 1 +Cellular component maintenance 0.3846101304739732 0.6313948439940508 0.5277823864471034 1.0 0.8835927235674561 11 Q14203,Q07157,Q9BRK5,Q15334,Q14247 5 +Negative regulation of ion transport 0.3259091747091426 0.6312541390640396 0.5278743680273905 1.0 0.8835927235674561 21 P62942,P80404,O95747,O75915,P14373,Q9UKS6,Q9UMX0,P0DP25,O14745 9 +Response to angiotensin 0.5111329789362151 0.6310049063637677 0.5280373163983212 1.0 0.8836434568815916 5 O75116,Q13464 2 +Membrane depolarization 0.4018894750503871 0.6300089115825735 0.5286887537026479 1.0 0.8837178830884477 9 Q9UII2 1 +Renal system vasculature development 0.6627776901397329 0.6297224506532997 0.5288761911942126 1.0 0.8837178830884477 3 O95747 1 +Regulation of histamine secretion by mast cell 0.6625310173697241 0.6288704925434715 0.529433845341927 1.0 0.8837178830884477 3 O95219,P51809 2 +Histamine transport 0.6625310173697241 0.6288704925434715 0.529433845341927 1.0 0.8837178830884477 3 O95219,P51809 2 +Histamine production involved in inflammatory response 0.6625310173697241 0.6288704925434715 0.529433845341927 1.0 0.8837178830884477 3 O95219,P51809 2 +Histamine secretion 0.6625310173697241 0.6288704925434715 0.529433845341927 1.0 0.8837178830884477 3 O95219,P51809 2 +Membrane invagination 0.3397170138065257 0.6283018069781547 0.5298062481319814 1.0 0.8837178830884477 17 O60493,P35579,P84095 3 +Protein localization to golgi apparatus 0.3772236263200106 0.6275863501157981 0.5302749528909927 1.0 0.8842782818923138 12 Q8TD16 1 +Regulation of neuroblast proliferation 0.5101513764025407 0.6269905173405879 0.5306654510668734 1.0 0.8847080167686463 5 P35221,P26367 2 +Myeloid leukocyte mediated immunity 0.3329527536167176 0.6259170559504508 0.5313693466988383 1.0 0.8849929244052499 19 Q12846,P11274,Q9NY93,Q92499,P78536,Q7Z434,Q9NR30,P51809 8 +Dna replication dependent chromatin organization 0.4395331234763882 0.62553861581982 0.5316176122307172 1.0 0.8849929244052499 7 Q13111,Q13112 2 +Intrinsic apoptotic signaling pathway in response to hypoxia 0.6611771872764575 0.6242006208175461 0.532495839217578 1.0 0.885353652350219 3 Q9Y4L1 1 +Sugar mediated signaling pathway 0.6611557041372895 0.6241265993266623 0.5325444465313898 1.0 0.885353652350219 3 P17480 1 +Taxis 0.244301796980142 0.6220293735259833 0.5339225536035919 1.0 0.886146500275817 79 P04083,Q9NWH9,P46108,Q9BVA1,P55011,P17301,O95747,P83731,P33176,P49593,Q13740,Q4VCS5,Q04721,O75592,Q9UNW9,Q9Y639,Q8WX93,P27361,P09429,P61011,P26367,Q12846,P84095,Q9BPU6,P11047,Q16555,Q8N8S7,P39019,Q15149,P26583,Q96JJ3,Q4KMQ2,P78536,Q9NVD7,Q9Y3A5,Q05655 36 +Positive regulation of sodium ion transmembrane transporter activity 0.4384269163195278 0.6203531755046194 0.5350252929752763 1.0 0.8875344875003215 7 O43707,P50570,Q12955,P05026 4 +Receptor clustering 0.3428308011863481 0.6192625223227508 0.5357434295577259 1.0 0.8878516045511641 15 P19022,Q14168,P21333 3 +Chemokine c c motif ligand 5 production 0.6594982078853019 0.6184233790562598 0.5362962906502053 1.0 0.8882694649095333 3 Q7Z434,P78540 2 +Regulation of potassium ion transmembrane transporter activity 0.388380092249468 0.6183929491079435 0.5363163445088048 1.0 0.8882694649095333 10 P05026 1 +Transport along microtubule 0.2661673797038182 0.617877015851496 0.5366564108165464 1.0 0.8884704296371352 56 P46821,Q13409,Q9UPN4,P23246,Q14203,Q8TD16,Q9Y496,Q9Y366,Q14168,Q8NCM8,P11142,P33176 12 +Positive regulation of protein dephosphorylation 0.3423163584678725 0.6159741336119924 0.537911591679896 1.0 0.8899468709132867 15 P26599,P42345,Q13526,O14974,P08238,P0DP25,Q15435 7 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.2713358195199827 0.6159174989544522 0.5379489716553296 1.0 0.8899468709132867 47 Q9UII2,P0DMV9,Q12834,Q9NZM5,P17980,O75150,P61956,O60826,Q9UMX0,Q6ZXV5 10 +Positive regulation of substrate adhesion dependent cell spreading 0.3376695267091043 0.6146742042280078 0.5387698987355067 1.0 0.8904608614887373 17 P63000,P60903,P60953,P46108,P27797,Q14155,O15144,Q07021,Q96AC1,P50570,Q13418,P21333,Q14185,Q92766,P46109,P07237 16 +Positive regulation of smooth muscle cell differentiation 0.6583953680727845 0.6146372389381533 0.5387943159203092 1.0 0.8904608614887373 3 Q96EB6,P32929 2 +Integrin mediated signaling pathway 0.3275376551291347 0.6137424678909706 0.5393855203787266 1.0 0.8909958682774799 20 P35579,P21333,Q9Y490 3 +Regulation of leukocyte mediated cytotoxicity 0.3873909894333492 0.6130568318052305 0.5398387623200107 1.0 0.8910651445671902 10 Q9BY67 1 +Activation of gtpase activity 0.3274036118865169 0.6127929170511838 0.5400132748151325 1.0 0.8910651445671902 20 Q4KMP7,P84095,P11274,Q9ULV4,Q96N67,O60343,Q12979 7 +Response to water 0.6405733186328647 0.6122630501747777 0.5403637322202715 1.0 0.8910651445671902 2 Q15149 1 +Response to hydrostatic pressure 0.6405733186328647 0.6122630501747777 0.5403637322202715 1.0 0.8910651445671902 2 Q15149 1 +Retinal ganglion cell axon guidance 0.5064238312731755 0.6118087163015761 0.5406643221607899 1.0 0.8913401915949473 5 P83731 1 +Development of primary sexual characteristics 0.2890269734959729 0.6105734789095951 0.5414819847586427 1.0 0.8920611322107365 31 P26583,P82094,Q14151,Q96EB6,O95747,Q15637,P80723,P35221,Q8IY37,O75874,P20042,Q13162 12 +Osteoblast differentiation 0.2761365002922806 0.6096217880107926 0.5421123751891683 1.0 0.8928436695946204 43 O60506,Q9NR12,P84243,Q9NY93,P62841,P38159,Q86V81,O75165,P61604,Q9P2E9,Q9NR30,P67936,Q00839 13 +Positive regulation by symbiont of entry into host 0.6391951488423291 0.6071710259538821 0.5437374184143557 1.0 0.8943602985126824 2 P19474 1 +Natural killer cell mediated immunity 0.3632604711132112 0.6068160876190591 0.5439729705153691 1.0 0.8943602985126824 13 Q9BY67,P30511 2 +Myeloid leukocyte cytokine production 0.4074937488829376 0.604021179215639 0.5458295613379045 1.0 0.8959105461302591 8 Q7Z434,Q92499,Q9NR30,Q96EB6 4 +Negative regulation of telomere maintenance via telomere lengthening 0.4348305642534752 0.6035750610631802 0.5461261975135068 1.0 0.8959105461302591 7 P09651,Q01780,P09874,Q00839 4 +Canonical wnt signaling pathway 0.2742112990519058 0.602087352918075 0.547115992575588 1.0 0.8968717378293718 44 Q13283,Q13308,Q8NBM4,P19022,Q9HCK8,P40818,O14745 7 +Synaptic transmission gabaergic 0.4615311864751515 0.6010013870769809 0.5478390624391474 1.0 0.8969535104373555 6 Q15910 1 +Protein localization to plasma membrane 0.2460221659246321 0.5987539357582775 0.5493369843206812 1.0 0.897861381144352 85 Q13464,Q9Y2J2,O75915,Q13136,Q9UN37,P33176,O15027,P15311,P19022,Q8IWJ2,O14745,P84095,Q9H4M9,P05026,Q01082,Q9H8Y8,Q13356,P21333,Q8N3R9 19 +Positive regulation of intracellular transport 0.2441772619099364 0.5966838515017208 0.5507184760861523 1.0 0.8981589443575485 78 Q9UPN4,P12270,Q9NPF5,Q14980,Q99496,P15311,Q9H7Z3,Q7Z6Z7,O15078,O00159,P21333,Q9GZY8 12 +Transmission of nerve impulse 0.3953721165017321 0.5962056996011889 0.551037818499003 1.0 0.8981589443575485 9 P42345,Q7Z406 2 +Positive regulation of maintenance of sister chromatid cohesion 0.6358875413450852 0.5950053803346642 0.5518398745422826 1.0 0.8981589443575485 2 O75367 1 +Presynaptic endocytosis 0.3504150270013454 0.5949663801045786 0.5518659441998888 1.0 0.8981589443575485 14 Q9NZM3 1 +Positive regulation of non motile cilium assembly 0.5020292528354859 0.5940413891392785 0.5524844305734193 1.0 0.8981589443575485 5 Q9UHD8 1 +Histone h3 k14 acetylation 0.43243773933468 0.5924816496058465 0.5535281052287357 1.0 0.8984556324983428 7 O75528,Q9HAF1 2 +Rna 3 end processing 0.2577719812904652 0.5916842773666414 0.5540620268932466 1.0 0.8984556324983428 67 Q9NQG5,Q96P16,O60832,O75150,P09012,Q05048,Q6P1J9,Q9P2I0,Q6PJT7,Q5VTR2,Q5VT52,Q9H0H0,Q9C0J8,P05455,P11940,Q8N684,Q12849,Q8N7H5,P18615,Q8N201,P33240,O00267,O94992,Q6UN15 24 +Negative regulation of neuron differentiation 0.3833134495019622 0.5911935062847568 0.5543907732331919 1.0 0.8984556324983428 10 Q9NP66,Q15648 2 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.3238467624350125 0.5877518157873225 0.5566988903485857 1.0 0.8997547423557 20 Q9NZM5,P62913 2 +Regulation of stress granule assembly 0.6504581586950791 0.5875964072559501 0.5568032231237383 1.0 0.8997547423557 3 Q13283 1 +Dna catabolic process endonucleolytic 0.4584336108428731 0.5875369967697991 0.5568431105872937 1.0 0.8997547423557 6 Q9GZR2 1 +Macrophage apoptotic process 0.6495726495726465 0.5846029018918009 0.5588147560132346 1.0 0.9020653996995806 3 P42771,Q96EB6 2 +Regulation of macrophage apoptotic process 0.6495726495726465 0.5846029018918009 0.5588147560132346 1.0 0.9020653996995806 3 P42771,Q96EB6 2 +Cysteine metabolic process 0.539161610590179 0.5809018621521266 0.5613065972555538 1.0 0.9045535923842524 4 P48506,P25325,P32929 3 +Cell chemotaxis 0.2708186880683435 0.5805746096830581 0.5615271886606845 1.0 0.9046902372085804 45 P26583,P84095,Q9NWH9,P55011,P78536,P39019 6 +Regulation of protein targeting 0.2867062312894917 0.5791828909743616 0.5624657738790482 1.0 0.9057643184873626 29 Q9UII2,P49257,Q99496,Q7Z6Z7,O00159,Q9GZY8 6 +Double strand break repair via break induced replication 0.3809583890406874 0.5786680598509285 0.5628131715738445 1.0 0.90586015724182 10 O00311,P33991 2 +Regulation of transcription by rna polymerase i 0.3224792823130326 0.5782063578459437 0.5631248068481121 1.0 0.90586015724182 20 P42345,Q9NZM5,P19338,Q9P0M6,P21333 5 +Positive regulation of sprouting angiogenesis 0.6312017640573493 0.577907622505535 0.5633264887544678 1.0 0.90586015724182 2 Q07157 1 +Formation of translation preinitiation complex 0.3807806884433911 0.5777260806610508 0.5634490681154172 1.0 0.90586015724182 10 P23588,P41214,Q15056 3 +Inositol phosphate metabolic process 0.4292263989863237 0.5776845562729208 0.5634771077169172 1.0 0.90586015724182 7 Q13572,Q96PE3 2 +Mitotic g2 m transition checkpoint 0.3582121632998847 0.577346740310684 0.5637052450393327 1.0 0.9060082852719022 13 O60934,Q9NZM5,Q13564 3 +Negative regulation of keratinocyte proliferation 0.4972838446271128 0.5750224106723877 0.565276140532101 1.0 0.9078760000542084 5 Q15648 1 +Regulation of cell cycle g1 s phase transition 0.275257394144747 0.5732147771799199 0.566499280141251 1.0 0.908546862584857 40 Q7L2J0,Q15910,P78536,P61254 4 +Intrinsic apoptotic signaling pathway in response to dna damage 0.2865768634093862 0.571799376256231 0.5674578999234223 1.0 0.909406911063228 27 Q13049,Q13573,P61254 3 +Fatty acid transmembrane transport 0.3905459862730268 0.5715122985562312 0.5676524260260214 1.0 0.9094998706554484 9 O14678,O43772 2 +Epiboly 0.400626990736689 0.570080479976463 0.5686231139112135 1.0 0.9101795254388524 8 P21333,P78536 2 +Female sex differentiation 0.3566470714085051 0.5682977583328259 0.5698328009021729 1.0 0.9110213869955066 13 Q9P2D1 1 +Regulation of establishment of protein localization to mitochondrion 0.3245359118713183 0.5680872676297981 0.5699757128607272 1.0 0.911031237782669 19 Q9UII2,P49257,Q99496,P31689,Q7Z6Z7,O14737 6 +Regulation of membrane protein ectodomain proteolysis 0.5356220058329244 0.5677188668120263 0.5702258784913086 1.0 0.911104381645164 4 Q13464 1 +Plasma membrane raft assembly 0.6444604740887824 0.5674157398557301 0.570431758607322 1.0 0.911104381645164 3 Q9UNF0 1 +Plasma membrane raft organization 0.6444604740887824 0.5674157398557301 0.570431758607322 1.0 0.911104381645164 3 Q9UNF0 1 +Regulation of dendritic cell differentiation 0.6441046959590012 0.5662257254219473 0.5712403441285689 1.0 0.9117400988463168 3 P01889 1 +Dna damage response signal transduction by p53 class mediator 0.3301201232050659 0.5651814542508671 0.5719503497005116 1.0 0.9122017667521856 17 Q01664,P61254,O60934,Q9UM54,Q96EB6 5 +Regulation of sister chromatid cohesion 0.3892621935072615 0.5649947996548722 0.5720773013345288 1.0 0.9122017667521856 9 P23246,P46100,P41227,Q8IY18,O75367,P39748 6 +Positive regulation of mapk cascade 0.2615137739612072 0.56242000691291 0.573829890964987 1.0 0.9141753581647823 53 Q13464,Q12802,Q15910,P18615,P30040,O60271,Q04721,Q86VI3,Q969S3,O75915,P19022,P46940,O75116,Q02952 14 +B cell receptor signaling pathway 0.6267916207276649 0.5619672223105117 0.5741383516303573 1.0 0.9141753581647823 2 Q9ULF5 1 +Regulation of macrophage proliferation 0.6267916207276647 0.5619672223105097 0.5741383516303586 1.0 0.9141753581647823 2 P27361 1 +Positive regulation of macrophage migration 0.6267916207276647 0.5619672223105097 0.5741383516303586 1.0 0.9141753581647823 2 P27361 1 +Positive regulation of macrophage chemotaxis 0.6267916207276647 0.5619672223105097 0.5741383516303586 1.0 0.9141753581647823 2 P27361 1 +Fatty acid homeostasis 0.4935427267664404 0.5601560302416277 0.575373015434367 1.0 0.9150477509724882 5 P54646,Q96EB6 2 +Regulation of response to cytokine stimulus 0.2850490622363458 0.5589903475622594 0.5761683077318303 1.0 0.9156567905795452 27 P0DMV9,Q7Z434,Q15648,P78536,Q13049,Q9NZI8 6 +Regulation of postsynapse organization 0.3314142870772745 0.5587706813538643 0.5763182340694395 1.0 0.9156766218389236 16 Q14444,Q9UJU6,Q96HC4,P19022,Q9UQB8,P11142 6 +Regulation of keratinocyte migration 0.5330756607322114 0.5582917484275626 0.5766451786377913 1.0 0.915698593262395 4 P42345,P58107 2 +Keratinocyte migration 0.5330756607322114 0.5582917484275626 0.5766451786377913 1.0 0.915698593262395 4 P42345,P58107 2 +Peptidyl threonine dephosphorylation 0.4512902295952904 0.5568159078218679 0.5776532139276433 1.0 0.9158867195698316 6 Q9P0J1,Q96HS1 2 +Regulation of mitotic sister chromatid segregation 0.3111889461877806 0.5557269175893287 0.5783975523682039 1.0 0.9164168533912992 22 Q14980,P12270,Q9Y6D9 3 +Negative regulation of actin filament polymerization 0.3063240200951403 0.5535490579434713 0.5798874977197419 1.0 0.917191479061947 23 P35241,O75146,P35611,Q13813,Q9NYL9,Q01082,P47755,Q05655 8 +Positive regulation of response to reactive oxygen species 0.6398831163724621 0.5521675403128542 0.5808335713023398 1.0 0.9173810459971996 3 Q14249 1 +Positive regulation of response to oxidative stress 0.6398831163724621 0.5521675403128542 0.5808335713023398 1.0 0.9173810459971996 3 Q14249 1 +Biological process involved in interaction with symbiont 0.2837823586038845 0.5507988838097096 0.5817715494101163 1.0 0.9177831532155282 28 Q01664,O75446,P10809,Q13573,P17980,Q9UHR5,Q96JM3,Q9H1E3,P11142,Q06787,P04406 11 +Peroxisome organization 0.3429912875280811 0.550393471281806 0.582049525667051 1.0 0.9177831532155282 14 O14678,Q9GZY8 2 +Regulation of erythrocyte differentiation 0.3429566916888584 0.550188232334889 0.5821902740151339 1.0 0.9177831532155282 14 P0DMV9,P26583,Q15648 3 +Killing of cells of another organism 0.4908644127087384 0.5495846735727146 0.5826042733991601 1.0 0.9182185165330504 5 P39019,P05204 2 +Regulation of collateral sprouting 0.6385460251271584 0.5477392246272146 0.5838709747497837 1.0 0.9195622774900848 3 P53990 1 +Positive regulation of transcription regulatory region dna binding 0.3959893620993286 0.5474850142051966 0.5840455631990833 1.0 0.9196198397618276 8 P07305 1 +Positive regulation of apoptotic signaling pathway 0.2809398394074177 0.5466971067365828 0.5845868422612195 1.0 0.9198199204403033 32 P23246,P61254,Q96EB6,Q13043,P62081,P30101,Q9NYF8,O14745 8 +Chromosome segregation 0.2911252432547104 0.5443214583829467 0.5862202830196197 1.0 0.921529883893194 143 Q8NBT2,P46013,Q9UQN3,Q12834,Q9Y3E7,P11387,Q9H0H5,Q13123,Q9HD42,Q15398,Q9UIG0,Q9UN37,P39748,Q7Z3K3,Q9Y448,P12270,Q02241,Q15050,Q96JM3,Q9NZZ3,Q9NQS7,P23246,Q9Y6D9,Q9H444,Q9UQE7,Q14980,Q9H3R5,Q14807,Q9Y6A5,Q9HC35,O95347,Q96EE3,Q14683 33 +Double strand break repair via nonhomologous end joining 0.3050440101586553 0.5440971027776045 0.5863746540653365 1.0 0.921544691055266 23 P26583,P18887,Q96T60,Q9Y2K7 4 +Positive regulation of erbb signaling pathway 0.4215650529386692 0.5428269106133436 0.5872489829490888 1.0 0.9219908401405544 7 O75146,P78536 2 +Platelet derived growth factor receptor signaling pathway 0.3740682503841936 0.5424785072166988 0.5874889096962854 1.0 0.9219908401405544 10 O00291,O75146,O14745 3 +Positive regulation of neuron projection development 0.281669691850813 0.5408101283941874 0.588638460972766 1.0 0.922525206816478 30 O60493,Q15910,Q9NY93,Q13308,Q9H4M9,Q14444,Q9UJU6,Q9ULH0,Q32P28,Q9UQB8,P21333,Q9H2P0 12 +Interleukin 2 production 0.3844107899271471 0.5405687840164158 0.5888048387498896 1.0 0.922525206816478 9 P14373,P04083,P15311,Q01082 4 +Positive regulation of immune effector process 0.2689605253715584 0.5387054771784665 0.5900900938337788 1.0 0.922525206816478 43 Q9BY67,Q12846,P04083,Q92614,Q7Z434,Q96EB6,Q96QE3,Q92499,O75179,P30511,P39019,Q9NR30,P51809 13 +Negative regulation of cell population proliferation 0.2658610976316968 0.5378049792273527 0.590711694062712 1.0 0.922525206816478 111 Q8IZP0,Q15637,P35221,Q15648,Q99627,Q13049,Q12824,Q32P28,P52756,P50402,Q9UII2,Q71SY5,Q6P1J9,Q13043,P98175,O14737,Q01085,O14745,P26367,P06748,P0DMV9,Q9Y6D9,O43815,Q01664,P17096,Q96IZ0,Q99496,Q96EY1,P02545,O14964,P58107,Q12904,P78540,Q53EL6,Q86U86,Q9UHI6,Q9Y366,P52758,P67870,O75691,O94788,Q13162 42 +Positive regulation of mrna metabolic process 0.2548077371695217 0.5359141303286211 0.5920178982073647 1.0 0.922525206816478 65 Q13464,P11940,O75175,P08621,P19338,Q13573,Q9Y2W1,P98179,Q96E39,P38159,Q8IZD4,Q92945,O75116,Q9NZI8 14 +Facultative heterochromatin assembly 0.3293705209917504 0.5349477460936245 0.5926859909423468 1.0 0.922525206816478 15 Q9UIF9,Q9NRZ9,P26358,Q96EB6,Q8NEY8,O75367,O95983 7 +Positive regulation of protein targeting to membrane 0.3666548818251189 0.5335588002725034 0.5936468191667594 1.0 0.923272080753036 11 Q9GZY8 1 +Inflammasome complex assembly 0.6187982359426589 0.5334671625691851 0.593710236257281 1.0 0.923272080753036 2 O00571 1 +Regulation of osteoblast proliferation 0.6187982359426589 0.5334671625691851 0.593710236257281 1.0 0.923272080753036 2 P06756 1 +Regulation of protein targeting to membrane 0.3603398479795046 0.5330986470014011 0.5939652956095665 1.0 0.9234531620422244 12 Q9GZY8 1 +Pyrimidine nucleoside triphosphate metabolic process 0.3398962894655363 0.5321280656093108 0.5946373003473795 1.0 0.9236930287427222 14 Q05682,P27144 2 +Embryonic skeletal system morphogenesis 0.4454531892742806 0.5320748117279472 0.5946741819690087 1.0 0.9236930287427222 6 O95747,Q6UB35 2 +Embryonic skeletal system development 0.4454531892742806 0.5320748117279472 0.5946741819690087 1.0 0.9236930287427222 6 O95747,Q6UB35 2 +Tissue migration 0.2568965985737332 0.5318464168488423 0.5948323714648276 1.0 0.9237233703260328 61 Q13464,P04083,Q9NWH9,Q16513,P42345,P51608,Q9ULV4,Q4VCS5,Q96EB6,O75116,Q5JRA6,P67870,P58107,P78536,Q13630,P35579 16 +Muscle system process 0.2527681679497617 0.5307431521410159 0.5955967785768359 1.0 0.9244794358990868 67 Q13464,Q05682,Q7Z406,Q96HC4,P46939,P50402,Q12802,Q14247,P25490,Q15910,P02545,Q9NYL9,P05026,P78540,P09874,P42345,P20020,O75116,P21333 19 +Cytoplasmic pattern recognition receptor signaling pathway 0.326853860326252 0.5301682574559459 0.5959952771340591 1.0 0.924882491560005 16 O75179,Q9NZM5,P0DMV9,Q9H078 4 +Cardiac ventricle development 0.328529449918175 0.5298069282937098 0.5962458010950931 1.0 0.925055781764208 15 Q13308,Q9P2D1,Q15648 3 +Negative regulation of intracellular protein transport 0.3498315673613872 0.5294046727670054 0.5965247573607959 1.0 0.9251231787347804 13 Q8NBM4 1 +Regulation of gtpase activity 0.2553351515272141 0.5263870161147306 0.5986193350434768 1.0 0.9267402875838596 63 Q4KMP7,Q15910,P11274,Q9NWH9,P84095,P42345,Q13526,Q9ULV4,Q4VCS5,P16949,Q86VI3,P55196,Q15555,Q96N67,P46940,Q12979,Q15042 17 +Positive regulation of intracellular steroid hormone receptor signaling pathway 0.4845396351360676 0.5248680914037344 0.5996748925533064 1.0 0.927466209777187 5 Q15648 1 +Zymogen inhibition 0.6163175303197261 0.5247289999614352 0.5997715944933832 1.0 0.927466209777187 2 P20810 1 +Protein folding 0.2715483944578904 0.5240741927539736 0.6002269374882476 1.0 0.927466209777187 119 P13667,Q9Y3C6,O95816,P10809,O76031,Q9BS26,Q9NYU2,Q99543,Q9UHV9,P14625,O75347,O60884,Q86YB8,Q9UNP9,P61604,Q9H2H8,Q32P28,Q13427,Q8WVJ2,Q6UX04,Q9Y266,P31689,P25685,Q16543,O14737,O15212,P07900,P62942,Q8IVD9,P0DMV9,O95757,Q08752,P08621,Q9UBS4,P49257,P30040,Q96EY1,P30101,P08238,Q13724,P38646,P50991,Q5F1R6,P49792,Q13217,Q12931,Q13451,Q14696,O75190,P54652,Q13356,P30414,P78371,P17987,Q9NXW2,Q9NUG6,P11142,Q13162 58 +Morphogenesis of an epithelial sheet 0.3648505828799095 0.5240030839540063 0.6002763948786038 1.0 0.927466209777187 11 P42345,P21333,Q8N3R9,P78536 4 +Regulation of chemotaxis 0.2782995238151383 0.5239649454630082 0.600302921612694 1.0 0.927466209777187 32 O75592,Q9NWH9,P78536 3 +Kynurenine metabolic process 0.6160418963616223 0.5237612970293435 0.6004445756182839 1.0 0.927466209777187 2 P00505 1 +L kynurenine metabolic process 0.6160418963616223 0.5237612970293435 0.6004445756182839 1.0 0.927466209777187 2 P00505 1 +Developmental cell growth 0.2576233096994185 0.522558957358893 0.6012812082029491 1.0 0.9285195643541844 51 Q96ST3,P46821,Q13740,Q12802,O60271,P25490,Q9UJU6,P11047,Q9NZM3,Q9BRT6,P46940,P53990,P08238,Q9H2P0,Q96HC4,Q14247,P18206 17 +Cellular response to acid chemical 0.3485841912428593 0.5223807277996535 0.6014052717184488 1.0 0.9285195643541844 13 P42345,Q9UQB8,Q15149 3 +Cell matrix adhesion 0.2679397011267727 0.5195114883655634 0.6034041036241102 1.0 0.931389744750654 42 Q13464,P17301,Q13136,P46939,P49593,P18206,Q9ULV4,Q15942,Q14247,P12814,P42771,P11274,Q7Z460,P06756,P60903,Q14155,Q9H2G2,O75116,Q13630 19 +Negative regulation of adaptive immune response 0.6297213988166935 0.518816765546448 0.603888525359735 1.0 0.9315687034869138 3 P30511 1 +Neuron projection guidance 0.2801567228206834 0.5185772673938046 0.6040555649833774 1.0 0.9315687034869138 27 Q13740,P84095,Q9BVA1,Q04721,O75592,Q9UNW9,P11047,Q9BPU6,P83731,Q8N8S7,Q9Y639,Q8WX93,P33176 13 +Sex differentiation 0.2700780621621399 0.518342667194745 0.6042192086110709 1.0 0.9315687034869138 39 Q9P2D1,P26583,Q14151,O95747,Q15637,O75874 6 +Erythrocyte maturation 0.629445822994207 0.5179222888462974 0.6045124901833194 1.0 0.9315896853114212 3 P18074,Q7L5Y9 2 +Negative regulation of translational initiation 0.3896166794410018 0.5168986349030685 0.6052269206139849 1.0 0.9318284597019568 8 Q6PKG0,P12270 2 +Regulation of biological process involved in symbiotic interaction 0.368726380883478 0.5149190029345082 0.6066096211896874 1.0 0.9333102301075514 10 O60493,P19474,Q9UPT5,P14373,Q96KP1,P06756,P07237 7 +Ovulation cycle 0.388956422106175 0.5137617035569108 0.6074186059295137 1.0 0.933418703863612 8 Q9H2P0,P04083,O75592 3 +Homophilic cell adhesion via plasma membrane adhesion molecules 0.3470248134590178 0.5136427207092022 0.6075018055687209 1.0 0.933418703863612 13 Q9BY67,O75147,P19022,Q9Y639,Q8WX93,O60245 6 +Detection of abiotic stimulus 0.3565945846138 0.5127808435164107 0.608104631359413 1.0 0.933418703863612 12 Q9BV73,P19022,Q13432,Q9UNS1 4 +Positive regulation of muscle cell differentiation 0.356574742876093 0.5126738821817984 0.608179462295467 1.0 0.933418703863612 12 Q13049 1 +Regulation of tau protein kinase activity 0.6278069731461031 0.5126140202106642 0.608221343961564 1.0 0.933418703863612 3 P08238 1 +Positive regulation of tau protein kinase activity 0.6278069731461031 0.5126140202106642 0.608221343961564 1.0 0.933418703863612 3 P08238 1 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.627679519085294 0.5122020003484093 0.6085096432726833 1.0 0.9335193794531018 3 Q7Z6Z7 1 +Outer ear morphogenesis 0.6269644334160434 0.5098925188192932 0.6101267634281253 1.0 0.935265646101742 3 P27361,O75569 2 +Positive regulation of focal adhesion assembly 0.3878844493443573 0.5086818987146193 0.6109752123308423 1.0 0.9361354334287192 8 Q13464,P60903 2 +Regulation of protein modification by small protein conjugation or removal 0.245395325289715 0.5082790965491606 0.6112576274298558 1.0 0.9363527969504942 91 Q9UER7,P0DMV9,Q12834,Q04323,Q9NZM5,Q13526,O75150,P62841,P62913,O75592,P62081,Q7Z6Z7,Q9UMX0,P61088,P46777,Q9NP66 16 +Regulation of muscle hypertrophy 0.3230479045260058 0.506673693409762 0.6123837916063319 1.0 0.9376034077220295 16 P02545,Q13464,P09874,P25490 4 +Pulmonary valve development 0.6108048511576731 0.50549910295355 0.6132083283462912 1.0 0.9380278747342452 2 Q04721 1 +Pulmonary valve morphogenesis 0.6108048511576731 0.50549910295355 0.6132083283462912 1.0 0.9380278747342452 2 Q04721 1 +Tangential migration from the subventricular zone to the olfactory bulb 0.6108048511576532 0.5054991029534806 0.6132083283463401 1.0 0.9380278747342452 2 Q02218 1 +Negative regulation of cell activation 0.2898494957810507 0.5053162245209701 0.6133367490757089 1.0 0.9380278747342452 25 P80404,P04083,Q9Y6D9,P11274,P78540,Q96IZ0,Q8WXW3,O15347,P30511 9 +Glutamate catabolic process 0.6105292171995493 0.5045445617652295 0.61387875606005 1.0 0.9386413295552108 2 P00505 1 +Peroxisome proliferator activated receptor signaling pathway 0.5180900220844418 0.5038333058448927 0.6143785209163504 1.0 0.9390714297415892 4 Q15648,Q96EB6 2 +Intracellular estrogen receptor signaling pathway 0.3038793266227679 0.5037430334920749 0.6144419637111358 1.0 0.9390714297415892 22 Q15424,P09874,O75528,Q15648,Q9GZZ9 5 +Telomerase holoenzyme complex assembly 0.5170327669038389 0.5000607956108557 0.6170322700494255 1.0 0.9408718203408728 4 P08238 1 +Postsynaptic membrane organization 0.3851655364704056 0.4958722687413522 0.6199845326325428 1.0 0.9435699204492064 8 Q96EY1,P19022,Q15334 3 +Negative regulation of histone h3 k27 methylation 0.6225530741659742 0.4957278345839794 0.6200864460441018 1.0 0.9435699204492064 3 O75367,Q7KZ85 2 +Negative regulation of innate immune response 0.3211938998107309 0.4953586889179357 0.6203469500935574 1.0 0.9435699204492064 16 P46108,Q9NX58,Q9Y4E8,P30511,P39019,P19474 6 +Regulation of protein localization to chromosome telomeric region 0.352681039248206 0.4918269683126498 0.6228416700720116 1.0 0.9449958384642444 12 P50991,P17987,Q9NVN8,O60832,Q9BVP2,P40227,P78371,P48643,P49368,O75367,P50990 11 +Negative regulation of leukocyte proliferation 0.3742068555928858 0.4903162195113746 0.6239101514236813 1.0 0.9449958384642444 9 Q9Y6D9,P78540 2 +Fibroblast apoptotic process 0.4348907113316724 0.488203178625204 0.6254059333048287 1.0 0.9451292730616816 6 Q9HCK8 1 +Circadian regulation of gene expression 0.3150062873164501 0.4855225266448854 0.6273057373399638 1.0 0.9464001918262538 18 P11387,Q7Z6Z7,O75592,Q9Y2K7 4 +Dna catabolic process 0.4085823268957772 0.4853216233064004 0.6274482192778446 1.0 0.9464001918262538 7 Q9GZR2 1 +Cardiac cell development 0.3173756499310957 0.4846539901990919 0.6279218087381477 1.0 0.9464001918262538 17 Q12802,P42345,Q15149,P02545,Q96HC4,P25490 6 +Arginine metabolic process 0.4740164687173299 0.4845640596892805 0.6279856131891255 1.0 0.9464001918262538 5 Q9ULX3 1 +Regulation of chromosome separation 0.2727652708137963 0.4842156729826544 0.6282328149777114 1.0 0.9464001918262538 33 P12270,Q9Y6D9,Q14980,Q13123,Q15398 5 +Cardiac neural crest cell differentiation involved in heart development 0.6189055507294464 0.4841252111207343 0.628297010052127 1.0 0.9464001918262538 3 P27361 1 +Response to x ray 0.3511937752433657 0.4839409208795759 0.628427797903357 1.0 0.9464001918262538 12 P04083,Q9H1E3,P13010,P50570,P54132,Q12888,Q15046 7 +Import across plasma membrane 0.2920433250017951 0.4838799126207818 0.6284710970638467 1.0 0.9464001918262538 24 P11166,P55011,O75915,P05026,O14745 5 +Negative regulation of peptidyl lysine acetylation 0.3728087429700844 0.4835572049596909 0.6287001524101683 1.0 0.9465069882786512 9 Q96ST3,Q9BX68 2 +Negative regulation of anion transport 0.6186301436775578 0.4832532507932491 0.62891592936529 1.0 0.9465069882786512 3 O75915 1 +Cell junction maintenance 0.3726474242965162 0.4827793785324149 0.6292523943389592 1.0 0.9465069882786512 9 Q14203,Q07157,Q15334,Q9BRK5 4 +Negative regulation of neuroblast proliferation 0.6039140022050623 0.4818401931910386 0.6299194744170196 1.0 0.9466931400476128 2 P35221 1 +Positive regulation of transcription from rna polymerase ii promoter in response to stress 0.603914002205062 0.4818401931910377 0.6299194744170202 1.0 0.9466931400476128 2 Q92616 1 +Bone marrow development 0.6039140022050618 0.4818401931910374 0.6299194744170205 1.0 0.9466931400476128 2 Q9Y3A5 1 +Neurofilament cytoskeleton organization 0.6036383682469582 0.4809028472424552 0.6305855490806584 1.0 0.9466931400476128 2 Q16352 1 +Negative regulation of histone methylation 0.3620006813540971 0.4808890545039344 0.63059535239424 1.0 0.9466931400476128 10 P26358,Q96EB6,Q12824,O75367,Q7KZ85 5 +Regulation of cell killing 0.3564420606093139 0.480219225488696 0.6310715176504651 1.0 0.9466931400476128 11 Q9BY67 1 +Myotube cell development 0.5107055611955369 0.4776880156976428 0.6328722753545206 1.0 0.9484145906137404 4 Q9H7B4 1 +Positive regulation of protein polyubiquitination 0.471993640258401 0.4769407657603435 0.6334043021379396 1.0 0.9484145906137404 5 O75150 1 +Organelle membrane fusion 0.2698993946251001 0.4769347447802056 0.6334085897240478 1.0 0.9484145906137404 35 O43752,P04083,Q9BSR8,Q9UQN3,Q9Y3E7,Q15075,O95721,Q9UN37,P51809 9 +Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 0.4719714723806114 0.4768574533880294 0.6334636306103203 1.0 0.9484145906137404 5 Q9UII2 1 +Regulation of metal ion transport 0.2523279074194116 0.4761939362456817 0.6339362190739151 1.0 0.9486108756130816 60 O14745,Q9P2D1,Q09666,P54652,O95747,Q9UKS6,P05026,P21333,P46939,P33176 10 +Negative regulation of endothelial cell proliferation 0.471692228472136 0.4758084158927629 0.6342108736086258 1.0 0.9486108756130816 5 Q9UII2 1 +Protoporphyrinogen ix biosynthetic process 0.5098634547557919 0.4747373135227519 0.6349742186240741 1.0 0.9490550054468762 4 P08397 1 +Embryo development ending in birth or egg hatching 0.2837428083509757 0.4747130087675001 0.6349915444580074 1.0 0.9490550054468762 140 Q8IZP0,Q13572,Q96AY3,O95747,Q15648,Q92541,P26373,Q7Z6E9,Q9P2D1,P20290,O60934,Q4VCS5,Q12830,Q9UPT9,Q13308,P62081,Q9HCK8,P35579,Q13428,O43772,O75190,Q9Y366,Q14978,P25440,O94788 25 +Positive regulation of endothelial cell migration 0.2906459028753122 0.473738088758972 0.6356866885190815 1.0 0.9497521235510474 24 Q9NWH9,P78536 2 +Regulation of protein exit from endoplasmic reticulum 0.3598476330032503 0.4701619630680596 0.6382393073504327 1.0 0.9516397803312951 10 Q8NBM4 1 +Translocation of molecules into host 0.3791531373855631 0.4679400275660599 0.6398274778627797 1.0 0.95250812415321 8 Q86V81 1 +Peripheral nervous system myelin maintenance 0.5077727133637782 0.4674395128765549 0.6401854584382982 1.0 0.95250812415321 4 Q8N3R9 1 +Positive regulation of protein deacetylation 0.3693722194113283 0.4670807868931407 0.640442079733593 1.0 0.95250812415321 9 Q13363,Q9UHR5,Q96EB6 3 +Monovalent inorganic anion homeostasis 0.6134806876892605 0.4670578028487263 0.6404585232627962 1.0 0.95250812415321 3 P55011 1 +Positive regulation of plasminogen activation 0.6133830447105323 0.4667527154013013 0.6406768094161714 1.0 0.95250812415321 3 P60903 1 +Regulation of plasminogen activation 0.6133830447105323 0.4667527154013013 0.6406768094161714 1.0 0.95250812415321 3 P60903 1 +Regulation of chromatin assembly 0.3477110236478459 0.4656461191952442 0.6414688255487837 1.0 0.9533806818668046 12 Q96ST3,P12270,P26358,Q8NEY8,O75367 5 +Regulation of protein localization to cell periphery 0.2685232235915336 0.4652362291573366 0.6417622968408381 1.0 0.9534601304600282 35 P84095,O43491,Q14980,P15311,Q01082,Q13136,Q9UN37,P33176 8 +Regulation of endothelial cell migration 0.2718027264498654 0.463797592303892 0.6427927685168009 1.0 0.9534601304600282 31 P51608,Q9NWH9,P78536 3 +Cellular response to hydrogen peroxide 0.2936802581386052 0.4625560982661753 0.6436825830081918 1.0 0.9536980390404426 23 Q15910,P04083,Q14249,Q9NWH9,Q96EB6 5 +Response to zinc ion 0.5060140537802642 0.461332218300813 0.6445602732980102 1.0 0.9543812205678672 4 O75592 1 +Intrinsic apoptotic signaling pathway 0.2379315132123638 0.4609954878392983 0.6448018423560449 1.0 0.9543812205678672 87 P23246,P09874,P61254,O60934,Q13573,P30040,P31689,Q969S3,O75915,P62081,Q9Y4L1,Q9UMX0,Q13049,Q92974,Q96QE3,Q9NYF8,O14745,Q15233 18 +Positive regulation of chemokine production 0.3678614821682338 0.4599006637518564 0.6455875237596682 1.0 0.9546956899637978 9 Q13049,P78536 2 +Negative regulation of response to dna damage stimulus 0.2720860959352547 0.4580745392298442 0.6468988902320474 1.0 0.9564226379773412 29 Q96QC0,Q96EB6,P18887,Q13049,Q13769,Q96QE3 6 +Immune response to tumor cell 0.6101995795516473 0.4568475977458999 0.6477805912674284 1.0 0.9568767847058997 3 P10809 1 +T cell mediated immune response to tumor cell 0.6101995795516473 0.4568475977458999 0.6477805912674284 1.0 0.9568767847058997 3 P10809 1 +Cell morphogenesis 0.3125142460671996 0.4563111974938779 0.6481662129862702 1.0 0.9570220103977244 194 Q96ST3,Q9NWH9,P46108,O60271,Q9NZM3,Q7Z406,P83731,Q96Q89,Q6SZW1,Q92974,Q9NZI8,Q9UNF0,O75955,P07942,P35241,Q9Y639,Q8WX93,O95487,P48681,P07900,P12814,Q9BPU6,Q15149,Q9UEE9,P51956,P53990,Q9UQB8,Q5VZL5,Q13464,P04083,Q8IZP0,Q96N67,Q96HC4,O75147,O75400,Q04721,Q14444,Q13043,P19022,P84095,P11047,P35579,O60610,P46821,Q9Y2J2,Q5VSL9,P46940,Q15648,P18206,Q13177,Q13740,Q9ULV4,P16949,O75592,O14745,Q9Y6W5,Q8N8S7,O75369,P35580,P08238,Q9H2P0,P60903,P21333,Q9BVA1,Q9Y4W6,P26038,P33176,Q66K74,Q9UJU6,Q9UNW9,P15311,P50570,Q14247,Q9ULH0,Q9UQ16,Q9BRT6,Q13596,O60828 78 +Central nervous system neuron axonogenesis 0.4267839229577222 0.4553837967322613 0.648833150221811 1.0 0.9575902656314892 6 P08238,O75592 2 +Maintenance of presynaptic active zone structure 0.5953693495038487 0.4531162981403941 0.6504650000031078 1.0 0.9582923109289484 2 Q8IUD2 1 +Regulation of phosphatase activity 0.3002811065339577 0.4526940198351764 0.6507690863471811 1.0 0.9583743667783856 21 P62942,Q13464,P42345,P17301,O14974,O75116,P14625,P67870,P08238,P0DP25 10 +Pattern specification process 0.2606937117693239 0.4524396782365404 0.6509522680384561 1.0 0.9583743667783856 42 Q8IZP0,Q12849,Q99496,Q12830,Q9Y366,O95747,P80723,O94788,Q8NCM8 9 +Negative regulation of cell cycle g2 m phase transition 0.3065890172700246 0.4509308931654095 0.6520393570710692 1.0 0.9593388243832736 19 O60934,Q9NZM5,Q13564,Q9UN37 4 +Negative regulation of g protein coupled receptor signaling pathway 0.3752806077778159 0.4502497464932674 0.6525303700073937 1.0 0.95981569123401 8 Q9NWH9 1 +Response to corticosterone 0.6075845597647347 0.44877243525514 0.6535958252534468 1.0 0.960568142033634 3 P20020 1 +Methylation 0.2665408000308441 0.4483409884978666 0.6539071234214122 1.0 0.9608136868622514 120 Q9NRZ9,Q8WVM0,O60885,Q9NPF5,Q13573,P51608,P46087,Q86YP4,Q92541,Q9HC36,O95983,P16402,O43709,P16403,P10412,Q7L2J0,Q96T37,Q15910,Q8IY81,P26358,Q96EB6,P02545,O94776,Q96L73,Q96FX7,P09874,Q15007,Q15291,P18615,P51610,Q9Y3Y2,Q9H7B4 32 +Pancreas development 0.3132177229243397 0.4477127854905157 0.6543604931465239 1.0 0.9608440831699674 16 P19022,O94788,Q9NWH9 3 +Negative regulation of proteasomal protein catabolic process 0.291430908522448 0.4469615492407963 0.6549028225326727 1.0 0.9614285155823414 23 Q9NZM5,P62913 2 +Snrna transport 0.5007560707268575 0.4432478229932883 0.6575864914242266 1.0 0.9641185898584038 4 Q9H814 1 +Hyperosmotic response 0.364277113160415 0.4430241422710902 0.6577482724266654 1.0 0.9641185898584038 9 P55011,P11166 2 +Negative regulation of striated muscle cell differentiation 0.3985648372247977 0.442449072826663 0.6581642750602057 1.0 0.9643207701254672 7 Q15910 1 +Negative regulation of response to biotic stimulus 0.276171269779854 0.4424332755168999 0.6581757042570548 1.0 0.9643207701254672 26 P01889,P78540,P46108,Q9NX58,Q9Y4E8,P30511,P39019,Q9UBC1,P19474 9 +Production of molecular mediator involved in inflammatory response 0.3238345369144666 0.4407255989776405 0.6594116618486612 1.0 0.9652412273023772 14 Q15910,Q99496,P39019,O95219,P51809 5 +Positive regulation of histone phosphorylation 0.6049076371656981 0.4405644005145419 0.6595283798679707 1.0 0.9652412273023772 3 P27361,Q06787 2 +Gastrulation 0.2655392322293524 0.4402277443416424 0.6597721672461065 1.0 0.9653859385445996 35 Q4VCS5,O95747,Q92541,P07942,P62753 5 +Myelin assembly 0.3979726293266293 0.4399587503435899 0.6599669834712492 1.0 0.9654135266364722 7 Q8N3R9 1 +Membrane fusion 0.2538483213067613 0.4398015448393695 0.6600808486684375 1.0 0.9654135266364722 47 O43752,Q9BSR8,Q9UQN3,Q9Y3E7,Q9UNZ2,Q15075,O95721,Q7Z6Z7,Q9UN37 9 +Regulation of hormone secretion 0.2654401097981603 0.43940562017738 0.6603676549276685 1.0 0.9656210090272448 35 Q12846,Q9P2D1,P04083,P82094,O00233,Q6WKZ4,Q8N183,P22059,O95219,Q12904,P51809 11 +Positive regulation of dendritic spine development 0.3481827358905254 0.438504153964519 0.661020859582141 1.0 0.9661520330268152 11 Q9UQB8,Q9BRT6,Q14444,Q9UJU6 4 +Negative regulation of interferon gamma production 0.5906835722160866 0.4376658967311085 0.6616284945947308 1.0 0.9664418388257214 2 P09429 1 +Dna methylation or demethylation 0.2805858545820453 0.4365475613844544 0.6624394994330205 1.0 0.9666071658121258 25 Q9NRZ9,Q15910,P09874,Q9NPF5,P26358,P51608,Q86YP4,O94776 8 +Regulation of dna helicase activity 0.6035290874000518 0.4363607856532366 0.6625749858135008 1.0 0.9666071658121258 3 Q04837,P49736 2 +Barbed end actin filament capping 0.3477299612660868 0.4362568435693005 0.6626503897751146 1.0 0.9666071658121258 11 P35611,P35241,P47755 3 +Pseudouridine synthesis 0.3721095885446696 0.4359475901887029 0.6628747554089813 1.0 0.9666071658121258 8 Q9NPE3,O60832 2 +Negative regulation of dephosphorylation 0.3124583846743686 0.4349032499364694 0.6636326555142817 1.0 0.9666071658121258 15 O75116,Q13464,Q12972,P46940 4 +Membrane protein ectodomain proteolysis 0.3472911894261867 0.434083085255687 0.6642281080130201 1.0 0.9666071658121258 11 Q9UKS6,P35579,Q13464,P78536 4 +Smooth muscle cell chemotaxis 0.6026143377674745 0.4335802786904812 0.6645932583710563 1.0 0.9666071658121258 3 Q9NVD7 1 +Cellular response to cadmium ion 0.3963373650352368 0.4331088541689564 0.6649356906426118 1.0 0.9666071658121258 7 Q9UER7 1 +Regulation of t cell mediated immunity 0.3714448365346781 0.4329708810981634 0.6650359244379054 1.0 0.9666071658121258 8 P10809,P01889,P30511 3 +Collagen fibril organization 0.3711861685112153 0.4318146271100362 0.6658761476566832 1.0 0.9670571298821304 8 Q96AY3 1 +Positive regulation of cell growth 0.2574072013661667 0.430749852024576 0.6666502664118732 1.0 0.9671655215234972 43 Q9NZM3,Q7Z4V5,Q9NXV6,P78536,Q13049 5 +Regulation of wnt signaling pathway 0.2489004931407214 0.4296063001188143 0.6674820534288379 1.0 0.9677400304554772 54 O60493,Q13283,Q13308,Q8NBM4,P19022,Q9HCK8,P40818 7 +Positive regulation of cell junction assembly 0.3314198555960485 0.429034182781801 0.6678983487047554 1.0 0.9681284285873322 13 Q9H2P0,Q13464,P60903,P49593 4 +Dna replication initiation 0.2886391603336606 0.4278780664112683 0.6687398966494229 1.0 0.968509554375396 23 Q13416,P25205,O60934,Q9BRX5,Q9ULV3,P33991 6 +Mrna catabolic process 0.2573864545466856 0.4274458568558297 0.6690546130183002 1.0 0.968509554375396 111 Q13464,Q9BRX2,Q6PKG0,Q92945,Q9NZI8,O75175,P52272,Q6P6C2,Q9Y2W1,Q8IZD4,P98175,Q6PJT7,P06748,P0DMV9,Q9UKZ1,Q9HAU5,Q6P2E9,Q13151,Q13310,P05455,P11940,Q15287,Q9BZI7,Q8NC51,O75116 25 +Negative regulation of dna binding 0.3698470783057404 0.425847278417176 0.670219133818267 1.0 0.968509554375396 8 Q96T23,Q01664 2 +Neutrophil homeostasis 0.5997623583742775 0.4249570464434276 0.670867987470428 1.0 0.968509554375396 3 P04083 1 +Osteoblast proliferation 0.5996691480562415 0.4246763943742426 0.6710725941982716 1.0 0.968509554375396 3 P19525,P06756 2 +Neural crest formation 0.4577965866119098 0.4246549285238677 0.6710882446769506 1.0 0.968509554375396 5 Q13428 1 +Programmed necrotic cell death 0.3305478074195913 0.4244694866194913 0.6712234539516593 1.0 0.968509554375396 13 Q13572,Q96HS1,Q92974 3 +Aldehyde biosynthetic process 0.4951085867011642 0.4241253943736752 0.6714743664489984 1.0 0.968509554375396 4 P29401 1 +Blood vessel endothelial cell migration 0.2880053838234961 0.4235887643458343 0.6718657508193637 1.0 0.968509554375396 23 P04083,Q4VCS5,P51608,Q96EB6,Q5JRA6,P78536,P35579 7 +Meiotic chromosome condensation 0.4574013878877535 0.4232313874663368 0.672126448521476 1.0 0.968509554375396 5 O95347 1 +Regulation of tissue remodeling 0.3939340293819209 0.4231136129567123 0.672212370789327 1.0 0.968509554375396 7 Q13464,P11274 2 +Regulation of dendritic spine morphogenesis 0.3447860430081906 0.4217494140054705 0.673207932467244 1.0 0.9691394673200582 11 Q9UQB8,Q96HC4,Q14444,Q9UJU6 4 +Chaperone mediated protein folding 0.2563939122082288 0.4216946749858648 0.6732478917378009 1.0 0.9691394673200582 43 P13667,P0DMV9,O75190,P54652,P25685,Q32P28,P61604,O14737,Q9NXW2,P11142 10 +Regulation of reproductive process 0.3066150569264865 0.4200876287604985 0.6744214398440571 1.0 0.9698151419529678 17 Q12834 1 +Vesicle organization 0.2593359205530065 0.4200276863237436 0.6744652282528838 1.0 0.9698151419529678 114 P04083,Q9BSR8,Q9UQN3,Q9Y3E7,Q15437,Q9HD42,Q9UN37,P40818,O60493,O43752,Q9NP79,P82094,Q92614,O15027,Q9Y5K6,Q9ULV4,P55735,Q5JRA6,Q86VS8,O95487,Q9NZZ3,P51809,Q12846,Q9H444,Q15075,O95721,O14964,O94979,Q9NP58,P22059,P53990,P61020,Q96ED9 33 +Regulation of establishment or maintenance of cell polarity 0.3684225247565941 0.4195333222127644 0.674826407048895 1.0 0.969944665320332 8 O75116,Q13464,Q96Q89 3 +Positive regulation of intracellular signal transduction 0.2917001335157025 0.418644643838845 0.6754758572875452 1.0 0.9706687146785216 159 Q13464,Q9NWH9,O60885,O60858,O60271,O75915,O75179,P46940,Q13049,O15344,Q9NR30,P26599,Q12802,P12270,Q04721,P62841,Q15555,P55735,P19022,P61088,Q8IUH4,Q9NYB0,Q6P1N0,Q01085,O14745,O00165,P62942,P0DMV9,P23246,Q9Y6D9,Q15910,Q9NY93,P61254,P30040,Q86VI3,Q96EB6,O00291,O60826,P62081,Q9Y6G9,P08238,Q7Z434,Q9NYF8,P18615,P14373,Q969S3,Q92499,O75116,P21333,O94992,Q96EE3,Q02952 52 +Ncrna export from nucleus 0.3924415817780919 0.4169505346782595 0.6767145891559516 1.0 0.9716104726200324 7 P06748,P05455,Q9H814,Q53F19 4 +Negative regulation of cell differentiation 0.2295233991085367 0.4167078613824573 0.6768921035026616 1.0 0.9716559348275656 82 P04083,Q8N4Q0,P51608,O60271,O95747,O15347,O75179,Q92785,Q15648,Q9H7N4,Q9NP66,P62805,P26599,Q86VS8,P25490,Q96T37,Q15910,P26358,Q15051 19 +Homologous recombination 0.3487043966962313 0.4160363708171387 0.6773833891514203 1.0 0.971816041839253 10 Q92878 1 +Cranial nerve development 0.454648046909587 0.4133638518547928 0.6793400546907429 1.0 0.9731390736896736 5 Q9P2D1 1 +Positive regulation of atp dependent activity 0.2773473171696126 0.4133621894691235 0.6793412724687284 1.0 0.9731390736896736 25 P25685,P20585 2 +Regulation of atp dependent activity 0.2622560126246225 0.4133010714043059 0.6793860449910945 1.0 0.9731390736896736 35 Q9UII2,Q8WXX5,Q04837,P08621,P54652,Q96EB6,P25685,Q9Y3Y2,P50570,P20585,Q5JTV8,P05026 12 +Presynaptic active zone organization 0.5955334987593017 0.4123002665483467 0.6801193533014092 1.0 0.9735614808109128 3 Q8IUD2,P20810 2 +Cytosolic transport 0.2314724290380896 0.4102537049182311 0.6816198486023692 1.0 0.9745495320238567 77 O60493,O43752,Q4KMP7,P33176,Q14203,Q9Y3E7,P49257,O60271,Q15075,O75494,P14373,P15311,Q86VS8,P21333,Q9Y5X2,Q8IWJ2,O94832 17 +Potassium ion transport 0.281640218762854 0.4102413300855564 0.6816289254043124 1.0 0.9745495320238567 24 O95747,P55011,P21333,P05026 4 +Regulation of chromosome condensation 0.357150180671835 0.41016156877835 0.6816874305404346 1.0 0.9745495320238567 9 O95347,Q9NTJ3,P84243,Q9UIG0 4 +Digestive system development 0.3179536672518979 0.4088383532626717 0.6826582917550135 1.0 0.9753097876199656 14 Q9HCK8,O75146,P04920 3 +Phosphorylation of rna polymerase ii c terminal domain 0.4532106904105769 0.4082479223526192 0.6830916685361299 1.0 0.9756694896814802 5 O60885,Q8WUA2 2 +Epithelial to mesenchymal transition 0.266053911117528 0.4078968296390197 0.6833494204223636 1.0 0.9756694896814802 27 Q13464,Q13428,Q15910,Q14978,P21333 5 +Mammary gland epithelial cell proliferation 0.4144418128606159 0.4069851658715004 0.6840188833439012 1.0 0.9764160704600536 6 Q15648 1 +Snrna metabolic process 0.265775594718557 0.405808958365952 0.6848829758897954 1.0 0.97648453043133 27 Q7L2J0,Q9NPE3,Q8N201,Q6P1N0,Q9H0H0 5 +Regulation of fatty acid biosynthetic process 0.3463759442690294 0.4050383683509109 0.6854493081442627 1.0 0.9765914778997202 10 Q8WXW3,P04083,Q92604,Q96EB6 4 +Activation of immune response 0.2459468002281066 0.4045155241983628 0.6858336644038749 1.0 0.9765914778997202 51 Q96ST3,Q13177,P23246,Q96PK6,Q96IZ0,Q8WXF1,P43243,P15311,P61088,Q7Z434,O60828,O94992,Q9NZI8,Q15233 14 +Negative regulation of cell cycle g1 s phase transition 0.316855322900984 0.402985489500027 0.6869588992248394 1.0 0.9770729116174242 14 Q15910 1 +Muscle adaptation 0.2958185559750229 0.4028497994337099 0.6870587234302905 1.0 0.9770729116174242 20 Q13464,Q15910,P09874,P02545,P25490 5 +Columnar cuboidal epithelial cell maturation 0.5796582138919407 0.4021985627467405 0.6875378998916781 1.0 0.9770729116174242 2 P04818 1 +Plasma membrane tubulation 0.4510606062877109 0.4006411820617173 0.6886843209513382 1.0 0.9774211645031564 5 Q9UKS6,Q9UNF0 2 +Positive regulation of telomere maintenance via telomere lengthening 0.2950423629767489 0.3980950962192934 0.6905600889619199 1.0 0.9790405006734008 20 P09651,P50991,O60832,P13010,P78371,P22626,P27361,P17987,Q96T60 9 +Positive regulation of interleukin 10 production 0.4862116808035571 0.3946654225775372 0.6930898242997241 1.0 0.9815825700435292 4 P10809,Q8WXW3 2 +Endocrine hormone secretion 0.4489914133479478 0.3933734056005993 0.6940437089605722 1.0 0.9818898256732496 5 Q6WKZ4 1 +Positive regulation of protein containing complex disassembly 0.3530236682224169 0.391577488300864 0.6953704239674905 1.0 0.9823393819291208 9 P48681 1 +Peptide antigen assembly with mhc protein complex 0.5883394669178814 0.3911345303205278 0.6956977981450025 1.0 0.9823393819291208 3 P30101 1 +Response to gamma radiation 0.3014463378857269 0.3903342894293203 0.6962893709324609 1.0 0.9823393819291208 17 P16104,O60858,P61254 3 +Cytoplasmic sequestering of nf kappab 0.4848609934703503 0.3902667697114434 0.69633929289652 1.0 0.9823393819291208 4 O60826 1 +Membrane repolarization 0.3857586071680247 0.3897786148969863 0.696700258396904 1.0 0.9823393819291208 7 P05026 1 +Centromere complex assembly 0.3380096526854275 0.3890690236514041 0.6972250872775585 1.0 0.9823393819291208 11 Q7Z7K6,Q9H3R5,Q7Z3K3,Q15398 4 +Regulation of establishment of protein localization to chromosome 0.3523888428610932 0.3887484869385329 0.6974622106233885 1.0 0.9823393819291208 9 P50991,O60832,P40227,P78371,P48643,P49368,P17987,P50990 8 +Positive regulation of establishment of protein localization to telomere 0.3523888428610932 0.3887484869385329 0.6974622106233885 1.0 0.9823393819291208 9 P50991,O60832,P40227,P78371,P48643,P49368,P17987,P50990 8 +Establishment of protein localization to telomere 0.3523888428610932 0.3887484869385329 0.6974622106233885 1.0 0.9823393819291208 9 P50991,O60832,P40227,P78371,P48643,P49368,P17987,P50990 8 +Protein neddylation 0.3523812468208196 0.3887146854925478 0.6974872176314102 1.0 0.9823393819291208 9 P46777,P62913 2 +Pentose phosphate shunt 0.3611432381550409 0.3878388103860369 0.6981353226260616 1.0 0.9826700864852784 8 P11413,P29401,O95336,P18669 4 +Nadph regeneration 0.3520166671530894 0.3870937212954374 0.6986868256766083 1.0 0.98293278305734 9 P11413,P29401,O95336,P18669 4 +Positive regulation of lamellipodium morphogenesis 0.4835547770154916 0.3860319406134834 0.6994730136082026 1.0 0.98293278305734 4 Q9ULV4 1 +Regulation of lamellipodium morphogenesis 0.4835547770154916 0.3860319406134834 0.6994730136082026 1.0 0.98293278305734 4 Q9ULV4 1 +Regulation of extrinsic apoptotic signaling pathway 0.2597652536793987 0.385815068067955 0.6996336350018304 1.0 0.98293278305734 34 Q13177,Q12846,P0DMV9,P26583,Q13043,P02545,P30101,Q92974,Q14247 9 +Retina development in camera type eye 0.2861648196062841 0.3853651742412582 0.6999668808111057 1.0 0.98293278305734 22 Q9P2D1,O75147,P11047,P20020,P83731,Q15648 6 +Negative regulation of extrinsic apoptotic signaling pathway 0.2778592506457232 0.3846101434051265 0.7005262778399195 1.0 0.9831274621802284 24 Q92974,P02545,P26583,Q14247 4 +Negative regulation of centriole replication 0.5854291240759086 0.3827063858975931 0.701937479038103 1.0 0.9834891796838572 3 Q96PK6 1 +Positive regulation of production of molecular mediator of immune response 0.2679687974694827 0.382580378411789 0.7020309211372644 1.0 0.9834891796838572 26 Q12846,Q96EB6,Q92499,P30511,Q7Z434,Q96QE3,Q9NR30 7 +Regulation of telomerase activity 0.2923324261593616 0.3816713524049224 0.7027051517674243 1.0 0.9841102911714849 20 O15381,P50991,O60832,P28482,P13010,P08238,P78371,P22626,P27361,P17987,P07900,Q96T60,Q14103 13 +Kinetochore assembly 0.407701265335159 0.3814173585307167 0.7028935825516258 1.0 0.9841102911714849 6 Q9H3R5,Q15398 2 +Positive regulation of smooth muscle cell migration 0.4455130421430994 0.381274961506652 0.7029992308143345 1.0 0.9841102911714849 5 Q96N67,P46108 2 +Nuclear envelope organization 0.2581615489765734 0.3806340713117976 0.70347479582834 1.0 0.984362337703928 35 Q14203,Q9H444,Q8NC56,Q9UQN3,Q9Y3E7,Q9UNZ2,P02545,Q5JTV8,Q9HD42,Q9NZZ3,Q9UN37 11 +Phosphagen metabolic process 0.5722160970231421 0.3789948062627716 0.7046917206616017 1.0 0.985030684651194 2 P12532 1 +Regulation of protein neddylation 0.4069462653078122 0.3785937202911857 0.7049895861168147 1.0 0.9850727343798894 6 P62913 1 +Adherens junction assembly 0.4446226326319448 0.378202289449741 0.7052803248286834 1.0 0.9850727343798894 5 P18206 1 +External encapsulating structure organization 0.2617580676203326 0.3769389488996756 0.7062189756295183 1.0 0.9850727343798894 28 O75190,Q96AY3,P11047,P07942 4 +Cardiac muscle cell membrane repolarization 0.4064289606870133 0.3766638164548025 0.7064234559223159 1.0 0.9850727343798894 6 P05026 1 +Positive regulation of cellular protein catabolic process 0.2434496925146326 0.376102433954519 0.7068407449107048 1.0 0.9850727343798894 54 Q9UII2,P0DMV9,Q12834,Q9NZM5,P17980,O75150,P15311,P61956,O60826,Q9UMX0,Q6ZXV5 11 +Positive regulation of transcription of nucleolar large rrna by rna polymerase i 0.3815547426084325 0.3730558010663336 0.7091069135172012 1.0 0.9850727343798894 7 P19338 1 +Myeloid cell development 0.2961994343087391 0.3727069904132062 0.7093665331500139 1.0 0.9850727343798894 18 Q8IZP0,Q04721,Q9Y6W5,Q9NYL9,Q15648,Q13310,P62753 7 +Trachea development 0.4793160507446158 0.3724203895820916 0.7095798752985631 1.0 0.9850727343798894 4 P27361,P28482,Q02750 3 +Trachea formation 0.4793160507446158 0.3724203895820916 0.7095798752985631 1.0 0.9850727343798894 4 P27361,P28482,Q02750 3 +Trachea morphogenesis 0.4793160507446158 0.3724203895820916 0.7095798752985631 1.0 0.9850727343798894 4 P27361,P28482,Q02750 3 +Positive regulation of intracellular protein transport 0.2416080891600012 0.371744889533427 0.7100827993236303 1.0 0.9852427005656113 62 Q9UPN4,P12270,Q9NPF5,Q99496,Q7Z6Z7,O00159,Q9GZY8,P21333,O15078 9 +Positive regulation of cell substrate junction organization 0.3343025725361256 0.3716312289795597 0.7101674344215048 1.0 0.9852427005656113 11 Q15555,Q13464,P60903 3 +Pronephros development 0.5813038220880964 0.3708959920703459 0.7107150004565783 1.0 0.9857970712141838 3 O15078 1 +Positive regulation of transferase activity 0.2544196311168542 0.3704588631417222 0.7110406220483019 1.0 0.986043427161904 113 Q8WVB6,Q8IZP0,Q9NWH9,Q12834,O60832,Q99627,Q9UER7,Q12802,O60934,Q13526,Q13043,P61088,Q92878,Q9NQS7,Q15910,P30040,Q9BRX5,Q96EB6,Q9H2P0,Q96T60,Q13432,P42345,Q969S3,P78536 24 +Regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.3340049980138473 0.3702454423158657 0.711199620459867 1.0 0.986058662123545 11 Q13043,P26583,Q92974 3 +Rna modification 0.2391625496693607 0.3689814869164324 0.7121415239545743 1.0 0.986859803684174 66 P05455,Q8WVM0,Q96DE0,Q9H9T3,Q7L2J0,Q96T37,O43709,O60832,Q6P6C2,Q8IY81,Q9NPE3,Q8WWH5,Q15007,P46087,Q9H3H1,Q9HC36,Q96FX7 17 +Regulation of core promoter binding 0.5803675557737082 0.3682380925552087 0.7126957090352684 1.0 0.9870901002479816 3 P26367 1 +Neuronal action potential 0.4414825445552566 0.3674469324924478 0.7132856691131686 1.0 0.9870901002479816 5 Q7Z406 1 +Neuroepithelial cell differentiation 0.4777243274014437 0.3673613781624946 0.713349476397136 1.0 0.9870901002479816 4 P19022 1 +Positive regulation of dendritic spine morphogenesis 0.3800356653245401 0.3670856167841717 0.7135551556677084 1.0 0.9870901002479816 7 Q9UQB8,Q14444 2 +Organelle fission 0.2948217683750174 0.3670025651416542 0.7136171046127084 1.0 0.9870901002479816 172 Q96HS1,P46013,Q9UQN3,Q96GD0,Q12834,Q9Y3E7,Q9H0H5,Q13123,P83731,Q9HD42,Q15398,Q9UIG0,Q9UN37,Q7Z3K3,O75147,P12270,Q9Y448,Q13526,Q02241,Q15050,Q96JM3,P43487,Q92878,Q9NZZ3,Q9NQS7,P0DMV9,Q9H444,Q9Y6D9,Q9UQE7,Q14980,Q9UNZ2,Q99640,Q14807,Q9ULW0,Q9Y6A5,Q9GZY8,P54652,Q9HC35,Q08379,P21333,O95347,Q96EE3,Q14683 43 +Membrane fission 0.4409248096413463 0.3655498713777378 0.7147009866098042 1.0 0.9873936814435436 5 Q9H444 1 +Positive regulation of protein modification by small protein conjugation or removal 0.2457406762014121 0.3654021654329857 0.714811225057288 1.0 0.9873936814435436 47 Q12834,Q9NZM5,Q13526,O75150,O75592,Q7Z6Z7,Q9UMX0,P61088 8 +Protein localization to endosome 0.327495633183704 0.3647008885777213 0.7153346952411375 1.0 0.9873936814435436 12 O75116,P26038,P15311,Q9UNF0 4 +Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.3793957357527592 0.3645823508916476 0.715423191283096 1.0 0.9873936814435436 7 Q12931,Q15233,Q96EB6 3 +Positive regulation of ubiquitin dependent protein catabolic process 0.2569506894311891 0.3640751432113271 0.7158018977705791 1.0 0.9875241197614452 34 P0DMV9,Q12834,Q9NZM5,P61956,O60826,Q9UMX0 6 +Protein stabilization 0.2242830456523533 0.3640587136538398 0.7158141660654487 1.0 0.9875241197614452 81 P0DMV9,Q9NZM5,Q13526,O15027,Q2M2I8,O75146,P62913,P51610,O00291,Q13043,O95785,P62081,P46777,P05026,P21333 15 +Negative regulation of protein exit from endoplasmic reticulum 0.476109562509907 0.3622588268509523 0.7171586229922333 1.0 0.9880377263153276 4 Q8NBM4 1 +Positive regulation of protein tyrosine kinase activity 0.3550273708724167 0.3619798763991558 0.7173670684901212 1.0 0.9880377263153276 8 Q13432,Q8IZP0,P78536 3 +Regulation of adherens junction organization 0.577544262907645 0.3602744572972146 0.7186418987175363 1.0 0.9884267378379588 3 P35611 1 +Regulation of retrograde protein transport er to cytosol 0.4393539705273022 0.3602286627318964 0.7186761417624863 1.0 0.9884267378379588 5 Q8NBM4 1 +Mitochondrial rna metabolic process 0.2588933903889993 0.3600064349885264 0.7188423213486805 1.0 0.9884267378379588 30 P52815,Q9UGM6,Q8WVM0,Q12849 4 +Modification of postsynaptic structure 0.4017926379678133 0.3595430799508326 0.7191888561609225 1.0 0.9885979503551968 6 O95793 1 +Response to nitric oxide 0.3780151225328512 0.3592056317129303 0.7194412639041972 1.0 0.9885979503551968 7 Q99707,P50570,P46108,Q14103 4 +Cellular response to reactive nitrogen species 0.3780151225328512 0.3592056317129303 0.7194412639041972 1.0 0.9885979503551968 7 Q99707,P50570,P46108,Q14103 4 +Positive regulation of early endosome to late endosome transport 0.438778063631259 0.3582858885319295 0.7201293774325277 1.0 0.9886343923509276 5 P26038,P15311 2 +Positive regulation of cytoplasmic transport 0.438778063631259 0.3582858885319295 0.7201293774325277 1.0 0.9886343923509276 5 P26038,P15311 2 +Protein localization to synapse 0.3358439054413079 0.3567519709974762 0.7212774948954408 1.0 0.9893248241699456 10 Q14168,P33176 2 +Embryonic placenta development 0.3169733648467735 0.3559083559339308 0.7219091978869105 1.0 0.9894912616264164 13 Q13263,O75190,Q12830,Q13043,Q15648,Q9NR09,P62993 7 +Modulation by host of symbiont process 0.2776384474608965 0.3558265767633587 0.7219704446127926 1.0 0.9894912616264164 23 Q01664,O75446,Q13573,P17980,Q9H1E3,P11142 6 +Diadenosine polyphosphate metabolic process 0.575825261364229 0.3554637100769182 0.7222422271960403 1.0 0.9894912616264164 3 Q9BW91 1 +Ncrna processing 0.3168885732639027 0.3548774349815992 0.7226814139333704 1.0 0.9896204685763852 234 Q9GZR2,Q8WVM0,Q9BSC4,O60832,Q14331,Q9Y237,P62913,P46087,Q8TDD1,Q2NL82,Q9NV06,Q9Y3B9,Q9HC36,Q9NR30,P50914,Q9P2D1,Q96DE0,O43709,Q9NZM5,P62841,Q15050,Q9H6R4,Q99547,Q96GQ7,Q9BVJ6,O43290,O15213,P62753,Q14137,Q14690,P82912,Q8IY81,P62424,Q9NPE3,P61254,Q9NY93,Q76FK4,Q969X6,Q99848,O43818,P78316,P62081,Q9NSI2,Q9H501,Q8N9T8,P62857,P39019,Q5JTH9,P46777,Q9H3H1,Q9ULX3,P61353,Q86U38,Q9H0H0,Q9H9Y2,P05455,Q96FX7,P62263,O00566,Q12849,Q8WWH5,Q8N201,P55769,Q9Y2W2,Q9Y3I0,Q14978,Q14692,Q92499,O75691,Q8NEF9,P62847,O94992 72 +Skin development 0.2484276601420376 0.3531036162455854 0.7240107619209359 1.0 0.9907734001734528 43 Q13464,P04083,P11274,Q9NWH9,Q14980,P16949,Q9NP58,Q13043,Q9P0M6,O75369,Q15648,Q15149 12 +Rna catabolic process 0.2716705047789932 0.3529907353295968 0.7240953861748611 1.0 0.9907734001734528 137 Q13464,Q9BRX2,Q6PKG0,O60832,Q92945,Q9NZI8,P39748,Q96DE0,O75175,P52272,Q6P6C2,Q9Y2W1,Q12972,Q8IZD4,P98175,Q8TDP1,Q9H814,Q6PJT7,P06748,P0DMV9,Q9UKZ1,Q9HAU5,Q6P2E9,Q13151,Q9BQ61,Q13310,P05455,P11940,Q12849,Q15287,Q9H7Z3,Q9BZI7,Q8NC51,O75116 34 +Histone threonine phosphorylation 0.5748552522746035 0.3527618912824898 0.7242669556956942 1.0 0.9907734001734528 3 Q9Y4B6,Q99986 2 +Ruffle organization 0.2945657874258904 0.3521129083617567 0.7247535880757758 1.0 0.991235558152498 17 P84095,P42345,Q9ULV4,Q9UJU6,Q9UHB6 5 +Vesicle budding from membrane 0.250101843593433 0.3507315351776144 0.7257897649466902 1.0 0.9921567850496144 40 O60493,Q9H444,Q92614,O15027,P55735,Q15437,Q5JRA6,O95487,Q9NZZ3,O94979,Q9UN37 11 +Regulation of cell substrate adhesion 0.2450060867073175 0.3486874923635243 0.7273239352883656 1.0 0.9931199132795844 46 P42771,Q13464,P60903,P18206,P46108,Q7Z460,Q9ULV4,Q13043,Q9H2G2,P50570,O75116,Q13630,P21333,P46939,P49593 15 +Negative regulation of b cell activation 0.4716532153530383 0.3483347051754099 0.7275888329737175 1.0 0.9931377777064035 4 O15347 1 +Muscle contraction 0.2448499756431542 0.3473500192318789 0.7283283772906906 1.0 0.993880305102536 46 P80404,Q13464,P78540,P42345,P50402,P67936,Q05682,Q7Z406,P06733,P20020,Q9NYL9,P05026,O75116,P21333,P46939,Q14247 16 +Protein nitrosylation 0.5726495726495692 0.3466529995105131 0.7288520240380907 1.0 0.9941875888906144 3 P23634,P04406 2 +Neutrophil degranulation 0.435167000793524 0.3462046995136486 0.7291888831610756 1.0 0.9942399385221212 5 P11274 1 +Neutrophil activation involved in immune response 0.435167000793524 0.3462046995136486 0.7291888831610756 1.0 0.9942399385221212 5 P11274 1 +Golgi to plasma membrane transport 0.2558479502061572 0.3449175815806131 0.7301563326087761 1.0 0.9951516955482133 32 O15027,Q567U6,O60826,Q96KP1,Q8IWJ2 5 +Regulation of water loss via skin 0.3973387235518449 0.3434014068529614 0.7312965012934514 1.0 0.9959561836031524 6 P16949,Q9NWH9 2 +Negative regulation of cellular amine metabolic process 0.5603638368246853 0.343337478447104 0.7313445887401113 1.0 0.9959561836031524 2 P23634 1 +Multicellular organismal response to stress 0.3733262705156878 0.3411937248192109 0.7329577470353894 1.0 0.9975088363730156 7 P51608 1 +Regulation of hematopoietic stem cell proliferation 0.5595369349503743 0.3409113146080036 0.7331703467019353 1.0 0.9975088363730156 2 P19525 1 +Metanephric tubule development 0.4689003957867806 0.3398510781276951 0.7339686800050931 1.0 0.9975088363730156 4 O95747 1 +Regulation of dephosphorylation 0.2527543681505291 0.3391446920864809 0.7345007319421395 1.0 0.9977676928666244 35 P62942,P26599,Q13464,P42345,Q13526,Q12972,O14974,P46940,P67870,O75116,Q15435 11 +Positive regulation of cell substrate adhesion 0.2559896806966282 0.3389839577599721 0.734621815297327 1.0 0.9977676928666244 30 Q13464,P60903,Q13043,P50570,Q13630,P21333,P46939,P49593 8 +Tumor necrosis factor mediated signaling pathway 0.2934202484548684 0.3376493475142385 0.7356274499137712 1.0 0.997838806156388 16 Q13049 1 +Positive regulation of toll like receptor 3 signaling pathway 0.5581587651598632 0.3368859657640419 0.7362028652614387 1.0 0.9978806690481598 2 O75955 1 +Positive regulation of heterotypic cell cell adhesion 0.5581587651598632 0.3368859657640419 0.7362028652614387 1.0 0.9978806690481598 2 O75955 1 +Regulation of protein localization to membrane 0.2410179204905671 0.3352391577610725 0.7374446856955146 1.0 0.9985480683137232 48 P84095,P15311,P19022,Q01082,O14737,Q9GZY8,Q13136,O00159,Q9UN37,P33176 10 +Regulation of cytoplasmic translational initiation 0.4670301386959808 0.3341395445571951 0.7382742609977968 1.0 0.9990621829712212 4 P42345 1 +Cytoplasmic sequestering of protein 0.3256437835096004 0.3321900135628713 0.7397457840428343 1.0 1.0 11 O60826 1 +Transcription coupled nucleotide excision repair 0.4663541092112413 0.332085536590633 0.7398246711322252 1.0 1.0 4 Q9HCS7,P19447,P18074 3 +Positive regulation of interferon gamma production 0.3941241408511809 0.3319429338950965 0.7399323501055104 1.0 1.0 6 P14373,P10809 2 +Neural tube development 0.2552626858546565 0.3317089253511558 0.7401090604727103 1.0 1.0 29 Q13572,Q13308,Q9Y366,P62081,P25440,O95487,O94788 7 +Neuroblast division 0.5670384720530862 0.3313328252807253 0.740393099272971 1.0 1.0 3 Q92974 1 +Asymmetric neuroblast division 0.5670384720530862 0.3313328252807253 0.740393099272971 1.0 1.0 3 Q92974 1 +Positive regulation of epithelial to mesenchymal transition 0.3934800924573388 0.3296669108897098 0.7416516585293709 1.0 1.0 6 Q15910 1 +Synaptic vesicle recycling 0.2856121283844872 0.3272358283172668 0.7434895242019222 1.0 1.0 19 Q9NZM3 1 +Neuron death 0.2255964620205109 0.3261819828479865 0.7442866722006314 1.0 1.0 76 Q9UER7,Q13464,Q9H444,P09874,P51608,P09104,O75915,Q9H2P0,P30511,Q6SZW1,P51858,P48681,Q9Y4L1,Q15233 14 +Cellular response to organic cyclic compound 0.259376791422013 0.3241611190419317 0.7458160565573233 1.0 1.0 124 Q96ST3,P04083,Q96GD0,Q6PKG0,Q13573,Q14151,O75915,Q8TDD1,Q15648,P11802,P40818,Q9UER7,P82094,O75528,P15311,O14745,P06748,P0DMV9,Q15910,Q01664,P26358,Q96EB6,Q13185,P54132,Q7Z434,Q9GZZ9,O60610,Q15424,P09874,O96013,P21333,P20020,O75116,O60828,Q9H7B4,P11142 36 +Negative regulation of cell division 0.5639910775378677 0.3231473147017686 0.7465836788379632 1.0 1.0 3 Q9UN37 1 +Chaperone mediated protein complex assembly 0.3100537144582905 0.3228963874818077 0.7467737122716844 1.0 1.0 13 P34932,P36776,P10809,P78371,O95456,P08238,O15212,P07900 8 +Positive regulation of mast cell activation 0.5638325329075232 0.3227240866354293 0.7469042089114399 1.0 1.0 3 P51809 1 +Positive regulation of mast cell activation involved in immune response 0.5638325329075232 0.3227240866354293 0.7469042089114399 1.0 1.0 3 P51809 1 +Response to dsrna 0.2904559035234381 0.3222960589150586 0.7472284185138671 1.0 1.0 16 P06748,Q92499,Q7Z434,O60828,Q9NR30 5 +Regulation of histone deacetylation 0.3098130061185611 0.3217731292754922 0.7476245722743275 1.0 1.0 13 O75528,Q96EB6 2 +Xenobiotic transmembrane transport 0.5520948180815759 0.3194490766093599 0.7493860009130984 1.0 1.0 2 P41440 1 +Regulation of receptor localization to synapse 0.5624483043837845 0.3190400894563149 0.7496961130097131 1.0 1.0 3 O15400,Q9Y639 2 +Defense response to other organism 0.2905388288748106 0.3176852891529583 0.7507236711433447 1.0 1.0 172 Q96ST3,Q9Y5A7,Q9BY67,Q13283,P04083,Q9Y3E7,O60858,Q9NUQ8,Q9Y4E8,O15347,O75179,P30511,Q15648,Q6SZW1,Q13049,Q92974,Q9NR30,Q9NZI8,P07814,P33176,Q15233,Q13177,P82094,Q8IWZ3,Q9NZM5,Q04721,Q9NV70,Q12906,Q15942,Q96JM3,Q16543,P19474,P51809,Q12846,P23246,Q9NY93,Q8WXF1,Q9NX58,Q9H078,O75369,P08238,P39019,Q7Z434,P04406,Q96PK6,P26583,P78540,Q53F19,O14802,Q13217,Q96SB4,P43243,P14373,O43164,Q92499,Q9UN86,P40429,P78536,O00159,O60828,O94992,Q05655,Q96EE3 63 +Negative regulation of protein dephosphorylation 0.3168968131396792 0.3158012463706855 0.752153372026203 1.0 1.0 12 O75116,Q13464,Q12972 3 +Detection of stimulus 0.280926477895829 0.3157253910927246 0.7522109524530332 1.0 1.0 20 Q9BV73,Q9BY67,P19022 3 +Mrna cleavage involved in mrna processing 0.34353233564202 0.3154202036799529 0.7524426288609649 1.0 1.0 8 Q8N684,Q16630,Q9P2I0,P33240,Q6UN15 5 +White fat cell differentiation 0.4605644657850446 0.314726631220356 0.7529692222633728 1.0 1.0 4 Q13363,Q96EB6 2 +Regulation of muscle adaptation 0.2855466945245632 0.3142549561867055 0.7533274062092636 1.0 1.0 18 P02545,Q13464,P09874,P25490 4 +Negative regulation of epithelial cell migration 0.321513728355791 0.3140449929328008 0.7534868666827597 1.0 1.0 11 P51608,P67870,P58107 3 +Negative regulation of histone acetylation 0.3660142450457181 0.3138977578136478 0.7535986933874315 1.0 1.0 7 Q96ST3 1 +Somatic diversification of immunoglobulins 0.2775167752515286 0.3129544876813015 0.7543152400342874 1.0 1.0 21 O60934,P20585 2 +Positive regulation of cellular component biogenesis 0.2591535496774559 0.3128995181738309 0.7543570036538232 1.0 1.0 125 Q96ST3,P46821,Q96SN8,Q13464,Q13283,Q9NWH9,P51608,Q9UHD8,Q8NEY8,O60504,O95219,P62993,P26038,Q9UN37,O75955,P49593,P12270,Q71SY5,O75146,Q9NQW6,Q15555,P50570,Q14008,P07900,Q14247,P0DMV9,Q14203,Q7Z460,Q9P270,P26358,Q14980,Q9Y6W5,O14964,Q15042,Q9H2P0,P60903,P42345,Q16625,Q9UQ16,O75116,Q9UN86,P55072,Q9UQB8,Q13112,Q06787 45 +Negative regulation of rig i signaling pathway 0.5593782634045956 0.3109412822443065 0.755845260252809 1.0 1.0 3 Q8TAT6 1 +Positive regulation of rna export from nucleus 0.4592026228730276 0.310704694052661 0.7560251284279134 1.0 1.0 4 Q07666,Q9H7Z3 2 +Positive regulation of nucleobase containing compound transport 0.4592026228730276 0.310704694052661 0.7560251284279134 1.0 1.0 4 Q07666,Q9H7Z3 2 +Response to retinoic acid 0.3073971561960812 0.3105957065922392 0.7561079915161952 1.0 1.0 13 O95747,Q13308,Q13573 3 +Embryonic digit morphogenesis 0.3650833465733005 0.3104941952175551 0.7561851730648774 1.0 1.0 7 Q9Y366 1 +Regulation of cell junction assembly 0.2467809159090175 0.3101810495434046 0.756423280604464 1.0 1.0 37 Q13464,O00159,Q9H2P0,Q96HC4,P18206 5 +Protein localization to cytoplasmic stress granule 0.387867766952266 0.31011785558812 0.7564713343920426 1.0 1.0 6 Q92499 1 +Detection of light stimulus 0.3877556519146497 0.3097326069841056 0.7567643045248122 1.0 1.0 6 Q9BV73,Q13432 2 +Positive regulation of viral genome replication 0.2862211396764527 0.3080392418054417 0.7580524725341073 1.0 1.0 17 O95793,P11940,Q16513 3 +Cellular response to estradiol stimulus 0.4578047435190246 0.3066009584629175 0.7591471240108503 1.0 1.0 4 P17301,Q9Y230,Q14103 3 +Cardiac muscle cell differentiation 0.278994383817832 0.3050928680937016 0.7602954228634704 1.0 1.0 20 Q12802,P42345,P25490,P02545,Q96HC4,Q15149 6 +Embryonic brain development 0.4223801793507324 0.3048697175191891 0.760465380399302 1.0 1.0 5 Q9Y3C6 1 +Myeloid cell apoptotic process 0.3408171603313041 0.3048334733209262 0.7604929860564338 1.0 1.0 8 P42771,P04083,Q7L5Y9,Q96EB6,P78536 5 +Positive regulation of tor signaling 0.3405770242484994 0.3039049898390289 0.7612002761448924 1.0 1.0 8 P55735 1 +Maintenance of synapse structure 0.3856452254056856 0.3025199875197107 0.7622556989843945 1.0 1.0 6 Q14203,Q15334,Q9BRK5 3 +Amino acid import 0.3232170425071015 0.3022685211510854 0.7624473731276911 1.0 1.0 10 Q9H9B4,O75915,O14745 3 +Dendrite morphogenesis 0.2503519390706696 0.3022218587329265 0.7624829420276786 1.0 1.0 31 O75147,Q8IZP0,Q6SZW1,Q9UQB8,O60828,Q96HC4,Q9NZI8 7 +Rna import into mitochondrion 0.545755237045192 0.3017081195405109 0.7628745780676196 1.0 1.0 2 Q8TCS8 1 +Keratinocyte development 0.4559783147340962 0.3012770328237732 0.7632032529367347 1.0 1.0 4 O75369 1 +Rna phosphodiester bond hydrolysis endonucleolytic 0.2453897667437238 0.300003689952178 0.7641743410180519 1.0 1.0 37 Q96DE0,Q14137,Q14249,Q86U38,Q15050,P78316,Q14692,Q8N9T8,Q2NL82,P52758,Q9ULX3,P39748 12 +Extracellular vesicle biogenesis 0.3177888497804377 0.2980670462725447 0.7656519922801448 1.0 1.0 11 O14964,Q9Y3E7 2 +Spermatid differentiation 0.2504640019068863 0.297567152193286 0.7660335481775535 1.0 1.0 27 P54652,Q9UPN4,P26583,P82094 4 +Cellular component disassembly involved in execution phase of apoptosis 0.361255776238644 0.2966742508917695 0.7667152172517127 1.0 1.0 7 Q9UKV3 1 +Immunoglobulin production 0.2552415287620099 0.296644877927143 0.7667376445721823 1.0 1.0 26 O60934,P20585 2 +Abscission 0.4542756650868804 0.2963529103800509 0.7669605829728239 1.0 1.0 4 Q9UN37 1 +Negative regulation of t cell differentiation 0.5536366602644838 0.2960644775115669 0.7671808413318004 1.0 1.0 3 P04083 1 +Water homeostasis 0.3210348932494716 0.2932567032422068 0.7693259452762564 1.0 1.0 10 Q9NWH9 1 +Mitochondrial rna catabolic process 0.3827203987746146 0.2926485070673735 0.7697908328059624 1.0 1.0 6 Q12849 1 +Positive regulation of actin nucleation 0.4526792761040408 0.29177057039105 0.7704620480584594 1.0 1.0 4 P14373 1 +Positive regulation of leukocyte degranulation 0.3596167985382701 0.2908435414575389 0.7711709828084368 1.0 1.0 7 Q12846,P30511,P51809 3 +Thyroid gland development 0.5515662164315924 0.2907873384799653 0.7712139695432079 1.0 1.0 3 P27361 1 +Dna deamination 0.4176551724137961 0.2901905574987939 0.7716704595914576 1.0 1.0 5 Q5RKV6,Q9NQT4,Q9NPD3,Q9NQT5 4 +Regulation of pattern recognition receptor signaling pathway 0.2666927820890954 0.2896411983998757 0.7720907455577719 1.0 1.0 23 Q9NZM5,O75179,Q9UMX0,Q6SZW1,Q9UBC1 5 +Acidic amino acid transport 0.3026649972079945 0.2892180053859828 0.7724145540494223 1.0 1.0 13 O75915,P55011,O14745 3 +Dna unwinding involved in dna replication 0.2806704245971179 0.2889782244097656 0.7725980413929869 1.0 1.0 18 P25205,P17096,Q9BRX5,P33991,P54132 5 +Positive regulation of protein k63 linked ubiquitination 0.5508142040510227 0.2888822248184908 0.7726715066237579 1.0 1.0 3 P61088 1 +Substrate dependent cell migration cell extension 0.4170078122910823 0.2882052907050372 0.7731895991387159 1.0 1.0 5 Q9Y5K6 1 +Regulation of binding 0.2429103298171853 0.2879675477284442 0.773371580070755 1.0 1.0 108 Q13464,Q9NWH9,O60869,P62913,P10586,Q96T23,P30533,Q13526,P16949,O75146,P48681,Q7L2J0,P07305,Q01664,Q9H2P0,Q96L73,P26583,P09874,Q9H1E3,Q08379 20 +Regulation of cation transmembrane transport 0.2332590450311719 0.2870840166020919 0.7740479902064554 1.0 1.0 52 Q9P2D1,Q09666,P54652,O95747,P05026,P21333,P46939,O14745 8 +Vascular associated smooth muscle cell apoptotic process 0.4506020147244793 0.2858583079612716 0.7749866472386024 1.0 1.0 4 P26358,Q53EL6 2 +Nucleoside diphosphate catabolic process 0.5495812612946405 0.285772203924527 0.7750525987477108 1.0 1.0 3 Q9BW91 1 +Ribonucleoside diphosphate catabolic process 0.5495812612946405 0.285772203924527 0.7750525987477108 1.0 1.0 3 Q9BW91 1 +Negative regulation of myeloid cell differentiation 0.3098408244449009 0.2849672986827873 0.7756691954908337 1.0 1.0 12 Q96T37,Q8N7H5,Q6P1J9,O15347,P62805 5 +Regulation of calcium ion transmembrane transport 0.2620141888205098 0.2846559072638731 0.7759077744978042 1.0 1.0 24 Q09666,Q9P2D1 2 +Mitochondrial protein processing 0.3802618737244205 0.2844643899174764 0.776054519997694 1.0 1.0 6 Q9Y4W6,Q9UJZ1 2 +Negative regulation of immune effector process 0.3013821036012698 0.2835429578564905 0.7767606565384411 1.0 1.0 13 P39019,P30511,P04083 3 +Response to human chorionic gonadotropin 0.5388643880926005 0.2830063884402899 0.7771719398530388 1.0 1.0 2 P48506 1 +Cell killing 0.2615425497857094 0.2818794766452365 0.7780359269540515 1.0 1.0 24 Q9BY67,P05204,P08238,P30511,P39019,P33176,P51809 7 +Anterior head development 0.5377618522601861 0.2800714260866144 0.779422706443921 1.0 1.0 2 Q13206 1 +Regulation of peptide transport 0.2474992933975489 0.2782664009339591 0.7808078660994171 1.0 1.0 28 Q8N183 1 +Lamellipodium organization 0.247029648990587 0.2774800947289271 0.7814114880806091 1.0 1.0 30 Q8IZP0,P42345,Q16625,Q9ULV4,Q9Y6W5,P50570,Q14247,P18206 8 +Positive regulation of locomotion 0.2293494615747676 0.2774023424214649 0.7814711831878234 1.0 1.0 94 P04083,Q9NWH9,O60271,O95747,Q96N67,Q13049,Q92974,P07942,Q8IX12,Q07157,Q13043,Q15555,Q5JRA6,Q96EB6,O00159,O60610,P42345,P78536,O75116,Q13630,Q02952 21 +Establishment of centrosome localization 0.4474999724129547 0.2771365861757382 0.7816752299075584 1.0 1.0 4 P15311 1 +Response to reactive oxygen species 0.239239986048181 0.2754027646891028 0.7830068202699174 1.0 1.0 42 P00374,Q9NWH9 2 +Negative regulation of blood vessel endothelial cell migration 0.4126841788506712 0.2751086985450821 0.7832327288731109 1.0 1.0 5 P09429,P51608,P67870 3 +Rna splicing via endonucleolytic cleavage and ligation 0.4126430373891912 0.2749854496736488 0.7833274170227387 1.0 1.0 5 Q92499,O94992 2 +Asymmetric cell division 0.3548634188383449 0.2742348491810324 0.7839041485119618 1.0 1.0 7 Q08379,Q92974 2 +Cell junction organization 0.2638448085777647 0.2742020731273966 0.7839293350322392 1.0 1.0 136 P46821,Q13464,Q12834,Q9Y2J2,Q16513,P51608,P10586,Q9Y4W6,P35611,P35221,Q13136,Q96HC4,O00192,O75955,P18206,Q13177,P49593,O75147,P35241,Q07157,Q13526,Q9ULV4,Q14444,Q9UJU6,Q15555,P19022,Q9Y639,Q14247,P12814,Q9Y490,Q14203,P11274,O43815,Q7Z460,Q9BRK5,P11047,Q96EY1,Q9Y6W5,Q14126,Q9H2P0,O00159,Q15149,Q15334,P60903,Q9UDY2,O95793,Q16625,Q14696,P55196,Q13112,Q9UQ16,O75116,Q9H2G2,P55072,Q9UQB8,P21333,P11142 57 +Polyol metabolic process 0.2467386844842244 0.2733618882138208 0.78457504622675 1.0 1.0 27 Q13572,P00374,P51608,P09417 4 +Roof of mouth development 0.3764859880901234 0.272100625026463 0.7855446489696711 1.0 1.0 6 Q9P2D1 1 +Positive regulation of extrinsic apoptotic signaling pathway 0.3157786602466713 0.2720632664650216 0.7855733736433073 1.0 1.0 10 Q13177,Q13043,P30101 3 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.2453991832193667 0.2719646345866612 0.7856492122413186 1.0 1.0 32 P0DMV9,Q12834,Q9NZM5,P61956,Q9UMX0 5 +Cardiac chamber development 0.2699180620635565 0.2712533367450014 0.7861961932893196 1.0 1.0 21 Q9P2D1,Q96T37,Q13308,P43243,Q15648 5 +Cell cell signaling by wnt 0.2216223259236125 0.2710457631469627 0.7863558352516935 1.0 1.0 75 O60493,O14745,Q13283,Q13308,Q8NBM4,P19022,Q9HCK8,Q92541,P40818 9 +Response to interleukin 4 0.3318304096255711 0.2709771115661822 0.7864086362029197 1.0 1.0 8 P08238,P11802,P39023,P49736 4 +Positive regulation of pattern recognition receptor signaling pathway 0.3154435300776116 0.2707370661775014 0.7865932663998076 1.0 1.0 10 P0DMV9,Q9Y4E8,O43164,O75179,P09429,O75955 6 +Epithelial cell differentiation 0.2504256711805492 0.2699312486791099 0.7872131462269196 1.0 1.0 119 P46821,Q13464,P04083,Q9NWH9,Q9BRX2,O60869,Q14151,O95747,P35611,Q15648,P18206,Q07157,Q04721,P15311,O14974,Q13043,P19022,P80723,O95487,O14745,Q15910,P11274,Q9UM54,Q14980,Q13308,P11047,O75369,O43598,Q15149,Q9UDY2,P55196,Q9P0M6,O75116 33 +Cellular response to vascular endothelial growth factor stimulus 0.3757992475124084 0.2698790931615195 0.7872532718144869 1.0 1.0 6 O00159 1 +Detection of visible light 0.4447444864231228 0.2694983244472528 0.787546231434409 1.0 1.0 4 Q9BV73 1 +Action potential 0.2745340511520951 0.268878446472876 0.788023223607538 1.0 1.0 19 Q7Z406,P21333,P05026 3 +Positive regulation of nitric oxide metabolic process 0.3751650365277778 0.2678349762614966 0.7888263468038654 1.0 1.0 6 P08238,P50570,P07900 3 +Axon extension 0.2455708094047327 0.2665683911343462 0.7898014954306136 1.0 1.0 29 Q96ST3,P46821,Q13740,Q9UJU6,P11047,P08238,Q9H2P0,Q14247,P18206 9 +Tube development 0.2765265085280987 0.266296785387577 0.7900106486387843 1.0 1.0 156 Q13464,P04083,Q9NWH9,Q13572,P55011,P51608,Q96AY3,O95747,Q05682,Q9UNS1,Q15648,O15078,Q9UII2,Q9P2D1,Q07157,Q4VCS5,Q04721,Q96JM3,Q13043,P19022,P80723,Q96PU8,Q5JRA6,O95487,Q96T37,P19338,Q13308,P04920,Q96EB6,Q9UGM6,P62081,Q9HCK8,O14964,P35579,Q12904,P78540,Q9Y366,P67870,P25440,O96013,P21333,O94788 42 +Rrna base methylation 0.4096365113358151 0.2660495508797101 0.7902010476402697 1.0 1.0 5 P46087 1 +Complement activation 0.4434638720352961 0.2659837436539417 0.7902517288824433 1.0 1.0 4 P35232,P10909,Q07021 3 +Rna surveillance 0.3051409618573826 0.2652378310997276 0.7908262532171211 1.0 1.0 12 Q13868,Q01780,Q8IYB8,Q9BRX2,Q5RKV6,Q06265,Q9NQT4,Q15024,Q9NQT5,Q9NPD3,Q96B26 11 +Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 0.330088570894399 0.2646316193063253 0.7912932595637938 1.0 1.0 8 Q9UII2 1 +Negative regulation of ion transmembrane transporter activity 0.2885014266666846 0.2645137396784123 0.7913840789980919 1.0 1.0 14 P62942,O95747,Q9UMX0,P0DP25,O14745 5 +Positive regulation of gtpase activity 0.2377523945080012 0.264503009303428 0.791392346271935 1.0 1.0 42 Q4KMP7,P60903,Q15910,P11274,P84095,Q8WU90,Q13526,Q9ULV4,P55196,Q15555,Q96N67,O60343,Q12979,Q15042 14 +Negative regulation of receptor signaling pathway via jak stat 0.5409275648736027 0.2644205781999005 0.7914558565316143 1.0 1.0 3 O14964 1 +Negative regulation of receptor signaling pathway via stat 0.5409275648736027 0.2644205781999005 0.7914558565316143 1.0 1.0 3 O14964 1 +Bile acid biosynthetic process 0.3217360083882422 0.262701949902193 0.7927803137568745 1.0 1.0 9 P22059,Q96EB6 2 +Regulation of atp biosynthetic process 0.3291333974824865 0.261182527574705 0.793951751581742 1.0 1.0 8 P27144,P09874,P55072 3 +Acid secretion 0.4411727613610925 0.2597523239980561 0.7950548287758268 1.0 1.0 4 O75146,O14745 2 +Pyridine containing compound catabolic process 0.4072819323344352 0.2591498161658687 0.7955196495359262 1.0 1.0 5 Q96GD0 1 +Negative regulation of transporter activity 0.2782223299085349 0.2586887521545081 0.7958753987144651 1.0 1.0 15 P62942,O95747,Q9UMX0,P0DP25,O14745 5 +Cell fate determination 0.4071032722575756 0.2586298416342258 0.7959208561324183 1.0 1.0 5 Q04721 1 +Nucleolus organization 0.3118952718842678 0.2568836788331775 0.7972685703030207 1.0 1.0 10 P39019,O75367,Q14978,Q96EB6 4 +Positive regulation of histone h3 k27 methylation 0.5275633958103547 0.2536890150966924 0.7997358211808065 1.0 1.0 2 Q9Y483 1 +Negative regulation of immune response 0.2434477991176196 0.2525830523372881 0.800590427727712 1.0 1.0 28 P04083,P11274,P46108,P78540,Q9NX58,Q9Y4E8,P14373,P30511,P39019,P19474 10 +Hypotonic response 0.535841691003207 0.2522682979839168 0.8008336903930273 1.0 1.0 3 O95747 1 +Negative regulation of ion transmembrane transport 0.2747248152257389 0.2517630245142934 0.8012242390242654 1.0 1.0 17 O95747,O75915,O14745 3 +Regulation of dna templated transcription in response to stress 0.2938550304276626 0.2513157848499802 0.8015699721678613 1.0 1.0 13 P25685 1 +Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.3103064296990597 0.2507930452936251 0.8019741188298688 1.0 1.0 10 P30040,Q9Y4L1,Q96EB6 3 +Positive regulation of canonical wnt signaling pathway 0.2708571060382034 0.2506959190253319 0.8020492160930879 1.0 1.0 19 Q13308,Q13526,P40818 3 +Nuclear transcribed mrna catabolic process exonucleolytic 3 5 0.3102209944751284 0.2504675348084388 0.8022258081689924 1.0 1.0 10 Q13868,Q15477,Q6PGP7,Q5RKV6,Q9NQT4,Q15024,Q9NQT5,Q9NPD3,Q96B26 9 +Regulation of high voltage gated calcium channel activity 0.5350240595370431 0.2503424528805268 0.8023225287547178 1.0 1.0 3 O75323 1 +Positive regulation of hormone secretion 0.268257905708523 0.2490675248635428 0.8033085493990588 1.0 1.0 20 Q12846,P82094,O00233,P22059,O95219,Q12904,P51809 7 +Histone h3 k36 methylation 0.403608005861003 0.2485591649223276 0.8037017989261346 1.0 1.0 5 Q96L73 1 +Type b pancreatic cell apoptotic process 0.4033103448275897 0.2477105544208426 0.8043583650908324 1.0 1.0 5 Q13247,P20810,O00330,O76024 4 +Negative regulation of toll like receptor signaling pathway 0.402412303969011 0.2451589417210156 0.8063333661617627 1.0 1.0 5 Q9UBC1,Q9UMX0 2 +Fibroblast migration 0.272818930084921 0.2429603100873587 0.808036144254729 1.0 1.0 17 Q9ULV4,O94776,P46940,Q15149,Q02952 5 +Dendritic cell migration 0.4013966868390517 0.2422889426622387 0.8085562810477822 1.0 1.0 5 Q4KMQ2,P09429 2 +Regulation of calcium ion transmembrane transporter activity 0.2723033455961873 0.2406055666465306 0.8098608353583063 1.0 1.0 17 Q09666,P54652,P05026 3 +Cell projection assembly 0.2474358270366211 0.2391067512413404 0.8110228068646157 1.0 1.0 119 Q13464,Q9UPN4,Q9UHD8,O15078,P18206,Q9Y5K6,Q9ULV4,Q14141,Q9UJU6,P15311,Q9BV73,Q15555,P50570,Q14247,O14745,Q8IVD9,Q14203,P84095,P27816,Q9H4M9,Q9NT62,O95721,Q9Y5K8,Q9Y6W5,Q15019,Q4KMP7,Q15051,Q9H223,P42345,Q8WXW3,Q16625,Q9Y496,Q9Y366,Q9UQ16,Q4KMQ2,Q15154,P21333,Q8NCM8,Q05655 39 +Negative regulation of atp dependent activity 0.3225914987871555 0.2381527165004315 0.8117626488450778 1.0 1.0 8 Q9UII2 1 +Regulation of histone ubiquitination 0.3068035748122895 0.2376156811460724 0.8121791870221859 1.0 1.0 10 O95071,O75150,P61088 3 +Positive regulation of protein localization to membrane 0.2399666871380414 0.2370656650207046 0.8126058485118439 1.0 1.0 32 P33176,P84095,P15311,O14737,O00159,Q9GZY8 6 +Bergmann glial cell differentiation 0.3994482758620724 0.2368298502741682 0.8127887930523765 1.0 1.0 5 Q02750,P08670,P28482,P27361 4 +Regulation of platelet aggregation 0.5284215357070956 0.2350768588555484 0.8141490794231825 1.0 1.0 3 P80404 1 +Negative regulation of phosphoprotein phosphatase activity 0.3139366318322364 0.2342694414808749 0.8147758080315799 1.0 1.0 9 O75116,Q13464 2 +Positive regulation of stem cell proliferation 0.4310535024820721 0.2331119093282178 0.8156745073281444 1.0 1.0 4 O60341,Q00839,O95251 3 +Positive regulation of actin filament bundle assembly 0.2717478493711755 0.2330940813290284 0.8156883507526331 1.0 1.0 16 P42345,O75116,P60903,O60504 4 +Germ cell development 0.2303658965932636 0.2328262584826942 0.815896321860371 1.0 1.0 46 Q9UPN4,P26583,P82094,P42345,Q99496,Q9UHI6,P54652,P62753 8 +Regulation of immune effector process 0.2270310933170604 0.2325217323006821 0.816132809777605 1.0 1.0 54 Q9BY67,Q12846,P04083,P11274,P46108,Q92614,Q9NY93,P10809,Q7Z434,Q96EB6,Q96QE3,Q92499,O75179,P30511,P39019,O95219,Q9NR30,P51809 18 +Regulation of phosphatidylinositol 3 kinase signaling 0.3133156321091717 0.2320744592691479 0.8164801819172274 1.0 1.0 9 Q9NZM5,O14745,Q96EB6 3 +Vitamin b6 metabolic process 0.4302914163496948 0.2311648567989413 0.8171867308353922 1.0 1.0 4 Q96GD0 1 +Regulation of nuclease activity 0.3046863341168407 0.2298201700718977 0.8182315107402474 1.0 1.0 10 P06748,P26583,Q05655,Q96EB6 4 +Negative regulation of transport 0.2237143066372436 0.2282629381544244 0.8194418350739965 1.0 1.0 93 P04083,O00233,O95747,O75915,Q8N183,P30511,P49790,Q9UNF0,O60493,P12270,P30533,Q8NBM4,Q9UMX0,O14745,P11274,P49257,P30040,Q07960,Q13432,P14373,Q6WKZ4,Q9UKS6,Q13438 23 +Positive regulation of chromatin binding 0.5252100094024955 0.2278373649056315 0.8197726775256435 1.0 1.0 3 Q71SY5 1 +Negative regulation of metaphase anaphase transition of cell cycle 0.2658618684601376 0.2269893338683814 0.820432036056105 1.0 1.0 19 P12270,Q9Y6D9 2 +Regulation of fibroblast migration 0.3033841834870048 0.2250898953902365 0.8219093416083201 1.0 1.0 10 Q02952,O94776 2 +Proline metabolic process 0.3612255151898703 0.224771003472224 0.8221574247702106 1.0 1.0 6 Q96C36,P54886,P30038 3 +Regulation of synaptic transmission glutamatergic 0.4269689102682745 0.2227748167552574 0.8237107688085425 1.0 1.0 4 P19022 1 +Regulation of calcineurin mediated signaling 0.3596005769252229 0.2199892161098931 0.8258795532882182 1.0 1.0 6 P42345 1 +Cellular copper ion homeostasis 0.3926086497372042 0.2181605873962386 0.827303992153734 1.0 1.0 5 Q9NP58 1 +Copper ion homeostasis 0.3926086497372042 0.2181605873962386 0.827303992153734 1.0 1.0 5 Q9NP58 1 +Neuroblast proliferation 0.2855438542866089 0.2179350824151852 0.8274796922360701 1.0 1.0 13 Q92974,Q9H0H5,Q96N67,P35221 4 +Positive regulation of t cell migration 0.4248274243248269 0.2174527286560056 0.8278555426033878 1.0 1.0 4 P78536 1 +Positive regulation of lymphocyte migration 0.4248274243248269 0.2174527286560056 0.8278555426033878 1.0 1.0 4 P78536 1 +Regulation of t cell migration 0.3586956976517611 0.2173484718947454 0.8279367847249575 1.0 1.0 6 P78536 1 +10 formyltetrahydrofolate metabolic process 0.520044463981773 0.2164515703781272 0.8286357715333261 1.0 1.0 3 Q6UB35 1 +Dicarboxylic acid catabolic process 0.3917241379310378 0.215803103326055 0.8291412292123252 1.0 1.0 5 Q9NRN7,Q4G176,P17174,P00505 4 +Negative regulation of alpha beta t cell activation 0.423896260120671 0.2151596496990318 0.8296428490211691 1.0 1.0 4 P04083,P78540 2 +Negative regulation of type b pancreatic cell apoptotic process 0.4238830667402097 0.2151272518512335 0.8296681073836871 1.0 1.0 4 Q13247,P20810,O00330 3 +Negative regulation of protein kinase activity by regulation of protein phosphorylation 0.3914152620485414 0.2149829554573971 0.8297806074456531 1.0 1.0 5 P06748,Q9ULV4 2 +Regulation of lipoprotein particle clearance 0.3155241413614432 0.2144654278496034 0.8301841243049897 1.0 1.0 8 P30533 1 +Negative regulation of autophagy 0.2452728306880891 0.2128323719212182 0.8314577130225338 1.0 1.0 25 Q08379,Q9H444,Q9NWH9 3 +Negative regulation of myosin light chain phosphatase activity 0.5180594977125177 0.2121618375763469 0.8319807781818409 1.0 1.0 3 Q13464 1 +Negative regulation of bicellular tight junction assembly 0.5180594977125177 0.2121618375763469 0.8319807781818409 1.0 1.0 3 Q13464 1 +Positive regulation of chromosome condensation 0.3901752210642222 0.2117064992664861 0.8323360173493941 1.0 1.0 5 O95347 1 +Corticosteroid receptor signaling pathway 0.3897931034482791 0.2107020960080305 0.8331197389460547 1.0 1.0 5 P35232,Q15185,O14497,Q04917 4 +Chromosome separation 0.2309500992583508 0.2106256808258673 0.8331793714268867 1.0 1.0 39 P12270,Q9Y6D9,Q14980,Q13123,Q15398 5 +Synapse assembly 0.2548016616317987 0.2092744475273787 0.8342339980470601 1.0 1.0 22 P19022,P51608,Q96HC4 3 +Mrna pseudouridine synthesis 0.4209325740684083 0.207946860742171 0.8352704592501705 1.0 1.0 4 O60832 1 +Epidermis development 0.2232073531178156 0.2073886368576985 0.835706356171553 1.0 1.0 52 Q13464,P04083,Q15910,P11274,Q9UM54,Q14980,Q13043,Q9P0M6,O75369,Q15648,O75116,O95487,Q15149,O14745 14 +Positive regulation of protein catabolic process 0.215081065179096 0.207369657524389 0.835721177337025 1.0 1.0 75 Q9UII2,P0DMV9,Q12834,Q9NZM5,P17980,O75150,P15311,Q9UKS6,P61956,O60826,Q7Z6Z7,Q9UMX0,Q13049,Q6ZXV5 14 +Aromatic amino acid family metabolic process 0.3551324503311361 0.2071045894017312 0.8359281779783536 1.0 1.0 6 Q99497,P61457,P09417,Q92947,O43708 5 +Response to osmotic stress 0.2570449981778011 0.2070411081984331 0.835977754279291 1.0 1.0 21 O95747,P55011,Q14978,P11166 4 +Cellular macromolecule biosynthetic process 0.1904874054697804 0.2061074175319277 0.8367070048130938 1.0 1.0 603 Q96ST3,Q6PKG0,P00374,P54098,P83731,Q8NE71,Q9P2E9,Q9NZI8,Q7Z6E9,P62917,P84098,P25205,P62841,Q12906,Q8IZD4,Q9H981,Q96PU8,Q86V81,P47914,Q92878,P25490,P06748,Q9UKZ1,P62424,Q9NPE3,P62750,Q9BRX5,Q9BY77,Q96EY1,Q13111,P62081,O60512,P62899,O95182,P26572,P54132,Q14197,Q15042,Q5ST30,Q8IXM3,Q13428,P82979,P40429,P55072,Q6P1L8,Q9NRF9,Q13464,Q8WVB6,Q14249,O60832,P11387,P98179,Q99543,Q8NC60,Q5T653,Q6ZXV5,Q9NR30,P12270,Q16576,O75175,O60934,Q14444,Q9UHA3,Q9NYB0,P46778,P13807,P33908,P82912,P61254,P17096,P19338,Q96EB6,Q9UGM6,Q9NRL2,Q13310,P46779,P61353,Q12904,P46782,P11940,P62263,P83881,Q14978,P82673,O75116,P35573,Q96RP9,Q9BRX2,Q7Z4H8,Q9NYU2,P62913,Q9ULV3,O75179,P26373,P61247,Q02809,P50914,Q9HAF1,Q9BTE6,Q96QE3,P35251,P46776,Q9NY93,Q96A35,Q96IZ0,Q9Y291,Q15056,Q9UJZ1,Q9Y2R9,O60841,P62857,P39019,P08238,P04406,O43432,Q04837,P36578,O00311,Q9BUQ8,Q8N1G4,P52758,Q15031,Q08379,O75717,P62847,Q9Y6M1,Q9UNS1,Q92945,P39748,Q9BYD2,P41214,Q02878,Q9Y3B7,Q8IUH4,P62753,P23588,Q9UQE7,P62273,O95785,P33991,P46777,Q96T60,Q13416,P05387,P42345,P49916,Q9H1E3,Q9BZI7,Q92499,Q13112 150 +Regulation of cellular response to insulin stimulus 0.264260620533171 0.2053696721254476 0.8372833133886131 1.0 1.0 17 O00159,P20020,Q9H1E3,Q9HCD5 4 +Interstrand cross link repair 0.5140588200969792 0.2036613463943693 0.8386181501661023 1.0 1.0 3 Q9H1E3 1 +Cardiocyte differentiation 0.2434311291708071 0.2031378108985142 0.8390273189620789 1.0 1.0 25 Q12802,P42345,P25490,P02545,Q96HC4,Q15149 6 +Regulation of cell development 0.2275339188987652 0.2028283516073062 0.83926919712262 1.0 1.0 100 P46821,Q13464,Q9BXP5,Q13573,P35611,Q96N67,P35221,Q13049,P18206,Q9P2D1,O75147,Q9ULV4,Q04721,Q14444,Q9UJU6,O14974,Q86VS8,Q15910,P39019,Q9H2P0,P60903,P26583,P42345,O75116,P53990,Q9UQB8,P21333 27 +Maintenance of dna methylation 0.4186035802912476 0.2023706587748801 0.8396269647344963 1.0 1.0 4 P26358 1 +Embryo development 0.2989179741862082 0.202318196644058 0.8396679752539231 1.0 1.0 218 Q96ST3,Q9Y3C6,Q13464,Q14249,Q8IZP0,Q9BVC5,Q13572,P11387,Q9H0H5,Q96AY3,O95747,Q15648,Q92541,O15078,P07942,P26373,Q7Z6E9,Q9P2D1,O75175,P20290,O60934,Q4VCS5,Q04721,Q12830,Q13043,P80723,Q16881,O95487,P48681,O14745,P62753,P11274,Q9UPT9,Q9UM54,Q13308,Q99496,P62081,Q9HCK8,P26572,O94788,Q13769,P35579,Q9Y4C8,Q13428,O43772,Q12849,O75190,Q9Y366,Q14978,Q14168,P25440,Q8NCM8,Q8N3R9 53 +Substrate dependent cell migration 0.2968972767971123 0.2022648011150012 0.8397097158732352 1.0 1.0 10 Q9Y5K6,Q14247 2 +Long chain fatty acid transport 0.2733727254918159 0.2018926030632676 0.8400006849076702 1.0 1.0 14 O14678,O43772 2 +Mrna modification 0.2812281023595869 0.2015488228604318 0.8402694574696654 1.0 1.0 13 O60832,Q15007,Q96FX7 3 +Dna biosynthetic process 0.215235009704323 0.199567674049006 0.8418187115384101 1.0 1.0 74 Q8WVB6,O60832,Q99543,P49959,P54098,Q9HAF1,P04818,P22626,P27361,Q9NYB0,P35251,Q92878,P07900,Q00839,P09651,Q9NPE3,Q9BRX5,Q96EB6,P13010,P08238,Q96T60,P50991,Q01780,P49916,P78371,P55072,P17987,Q9NRF9 28 +Mitochondrial transcription 0.3308104566097889 0.197468224697223 0.8434611448679943 1.0 1.0 7 P52815 1 +Regulation of ubiquitin dependent protein catabolic process 0.2216565093830599 0.1970779438966561 0.8437665431562558 1.0 1.0 64 P0DMV9,Q12834,Q04323,Q9NZM5,P62913,P61956,O60826,P62081,Q9UMX0,P46777,P55072 11 +Regulation of neuron projection development 0.2128853822163445 0.1970443182758385 0.8437928566112038 1.0 1.0 76 P46821,Q12834,P10586,Q32P28,Q6SZW1,Q96HC4,O60493,Q13177,O75147,Q14444,P19022,Q15910,Q13308,Q9H4M9,Q9H2P0,P53990,Q9UQB8,O60828,P21333 19 +Mrna methylation 0.330488303796169 0.1965263991779404 0.8441981719775005 1.0 1.0 7 Q96FX7 1 +Regulation of lymphocyte migration 0.3021481955144412 0.194392490252586 0.8458685696773063 1.0 1.0 9 O95747,P26038,Q5JRA6,P78536 4 +Pathway restricted smad protein phosphorylation 0.3834244882491264 0.194328209642988 0.8459188985387482 1.0 1.0 5 Q13526,P67870 2 +Regulation of translational fidelity 0.2628483874486009 0.1936585898080211 0.8464432184683353 1.0 1.0 15 P46782,Q99543,Q15031,Q9BTE6,Q5ST30 5 +Calcineurin mediated signaling 0.3294855446847963 0.1936099017095675 0.8464813444564356 1.0 1.0 7 P42345 1 +Inositol phosphate mediated signaling 0.3294855446847963 0.1936099017095675 0.8464813444564356 1.0 1.0 7 P42345 1 +Homocysteine metabolic process 0.4147821290678417 0.1933978552122114 0.8466473950210089 1.0 1.0 4 P25325,P22033,P32929 3 +Negative chemotaxis 0.5083904329031278 0.1919527354659958 0.8477792285008399 1.0 1.0 3 P06756 1 +Histone monoubiquitination 0.2936795831332623 0.1914074734292032 0.8482063653641179 1.0 1.0 10 Q8N7H5,Q99496,Q6P1J9,O75150,Q13620 5 +Regulation of calcium ion transport 0.228783749659687 0.1905224743546182 0.8488997337259505 1.0 1.0 37 Q9P2D1,Q09666,P54652,P14373,Q9UKS6,P20020,Q9UMX0,P05026,O75323,O60610 10 +Mrna alternative polyadenylation 0.3817931034482793 0.1902459557189774 0.8491164011969776 1.0 1.0 5 O43809,Q96MU7,Q16630,Q8N684 4 +Endocytic recycling 0.2326843631880879 0.1899364792293064 0.8493589064652503 1.0 1.0 29 O60493,O43752,Q567U6,O60826,Q07960 5 +Translesion synthesis 0.3281810654153989 0.1898501777597565 0.8494265346976753 1.0 1.0 7 P56282,P28340,Q14694,P55072,P49005,P12004 6 +Organelle assembly 0.3067663290645676 0.1890688962189157 0.8500388190100061 1.0 1.0 277 Q9UPN4,Q12834,P83731,Q96CS2,Q9UN37,O15078,Q12802,P82094,Q9NZM5,P62841,Q9BSJ2,Q9Y520,Q9NQS7,P06748,P0DMV9,P27816,Q14980,Q9H4M9,Q9UNZ2,P62750,O95721,Q15042,Q15149,Q7L2E3,Q15051,Q9Y366,Q14315,P53990,Q9Y281,Q8WWM7,Q9UQN3,Q14157,Q9HD42,Q7Z3K3,O75147,P12270,Q02241,Q14141,Q15050,Q9BV73,Q9NZZ3,Q9H444,P82912,Q9H3R5,Q9NYL9,Q9ULW0,Q9H8Y8,P46782,P62263,Q9Y496,Q9NP58,Q8NCM8,Q13283,Q9Y3E7,Q9H0H5,Q9UHD8,P62913,P46087,Q7Z4H7,Q15555,Q14137,Q9NT62,Q9Y2R9,Q9Y5K8,P62857,Q16527,P39019,Q15019,Q4KMP7,Q96PK6,Q9H223,Q8WXW3,Q9UN86,Q08379,P21333,Q14683,Q8IY37,Q15398,O95219,P26038,Q9NP79,Q9UJU6,P15311,Q02878,P50570,Q9UMX0,Q00839,Q8IVD9,Q96CW5,Q14203,Q9UQE7,O14964,P46777 93 +Secretory granule organization 0.3812982274758505 0.1890167242867279 0.8500797089762122 1.0 1.0 5 P82094 1 +Regulation of viral genome replication 0.2323882328835693 0.1888305062734047 0.8502256613967285 1.0 1.0 27 P11940,Q16513,O95793,Q6PKG0,Q7Z434 5 +Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.3484141838703055 0.1884717063081234 0.8505068931447954 1.0 1.0 6 Q96QE3,Q96EB6 2 +Torc1 signaling 0.3484124458670641 0.1884670025687248 0.8505105801189439 1.0 1.0 6 P42345,Q6PKG0 2 +Sno s rna metabolic process 0.2773254200438231 0.1873030298508114 0.8514230475501918 1.0 1.0 13 Q96DE0,Q01780,O60832,Q14978,Q9NPD3 5 +Nonribosomal peptide biosynthetic process 0.411748483177052 0.1864323840559029 0.8521056987742361 1.0 1.0 4 P48507,Q99735,P48506 3 +Mammary gland epithelium development 0.2995655712473864 0.1861708242912106 0.8523108028021786 1.0 1.0 9 Q15648 1 +Ribosome disassembly 0.3475155512539445 0.1860477510084177 0.8524073150852822 1.0 1.0 6 P41214 1 +Platelet derived growth factor receptor beta signaling pathway 0.5048915885248282 0.1849232953824164 0.8532891990308453 1.0 1.0 3 O75146 1 +Inflammatory response to antigenic stimulus 0.2991684376376406 0.184923280275631 0.8532892108799741 1.0 1.0 9 Q04721,P26583,Q15046 3 +Negative regulation of protein acetylation 0.2879738061946516 0.1845991297896983 0.8535434685399996 1.0 1.0 11 Q96ST3,Q9BX68 2 +Regulation of intracellular estrogen receptor signaling pathway 0.2604406045801254 0.1843601801357388 0.8537309059826161 1.0 1.0 15 Q9GZZ9,Q15648 2 +Myoblast fusion 0.3259577127915241 0.1835319712032975 0.8543806354009829 1.0 1.0 7 P35579 1 +Fibroblast proliferation 0.26837610776799 0.1831173238207215 0.8547059631575007 1.0 1.0 14 Q71SY5,Q96IZ0,Q13049,P11802,P50402 5 +Cellular response to chemical stress 0.2162263735642906 0.1830941793284273 0.8547241227989242 1.0 1.0 90 Q96ST3,P04083,Q14249,Q9NWH9,P00374,O95747,O75915,Q92974,Q15233,P31689,Q9UMX0,P0DMV9,P23246,Q15910,Q15149,P11166,P09874,O95793,Q969S3 19 +Neuron projection arborization 0.3053887035279847 0.182734983713484 0.8550059648745627 1.0 1.0 8 Q13464 1 +Killing by host of symbiont cells 0.5033300476743202 0.1818350312444219 0.8557121918300508 1.0 1.0 3 Q96JM3 1 +Succinyl coa metabolic process 0.4096867370100924 0.1817786002322591 0.8557564792497283 1.0 1.0 4 P36957,Q96I99 2 +Actin filament polymerization 0.2219096684094594 0.1810333725252533 0.856341381288253 1.0 1.0 47 P59998,P35241,P42345,O75146,Q9UJU6,O60610,P35611,Q13813,Q9NYL9,Q01082,Q9UQB8,P62993,P47755,Q05655,Q14247,O00165 16 +Negative regulation of telomere maintenance via telomerase 0.3455950578233727 0.1809220608955348 0.8564287525069183 1.0 1.0 6 P09651,Q01780,Q00839 3 +Regulation of osteoclast differentiation 0.4091913979415472 0.1806702182263619 0.8566264364654874 1.0 1.0 4 P42345 1 +Protein dephosphorylation 0.2139782624928211 0.1804304194926473 0.856814674894403 1.0 1.0 73 Q13464,Q9NQG5,Q96HS1,Q96P16,Q96GD0,P10586,P54098,Q15435,P26599,Q13526,Q12972,O14974,P62942,P08238,P42345,O60942,P67870,Q6PIU2,O75116,Q9P0J1 20 +Endothelial cell proliferation 0.2550753861081362 0.1798594314965896 0.8572629247202153 1.0 1.0 19 Q9UII2,P26583,Q96EB6,P78536,O94788 5 +Toxin transport 0.2671460176991134 0.1786449315207129 0.8582165117016156 1.0 1.0 14 P50991,Q9UJY5,O14786,P61923,Q99832,P48643,P78371,P35606,P49368,P17987,Q15650,Q8WVM8,P50990 13 +Spermatid nucleus differentiation 0.3769133986428126 0.1783114176539466 0.858478412515066 1.0 1.0 5 P26583,P82094 2 +Peptidyl tyrosine modification 0.2237583768644837 0.17809992256587 0.8586445028437588 1.0 1.0 44 Q13177,Q13432,Q8IZP0,Q9NWH9,P11274,Q9H223,P42345,P22059,P78536,Q92974,Q9H2P0,Q9UIG0,O00165 13 +Chromosome organization involved in meiotic cell cycle 0.2573353658300185 0.177341971034427 0.8592397851144766 1.0 1.0 17 Q92878 1 +Regulation of cell morphogenesis involved in differentiation 0.2297317024527778 0.1756866698507631 0.8605401083294182 1.0 1.0 31 O75147,P60903,P46108,Q9ULV4,Q14444,Q9UJU6,P50570,Q9UQB8,P21333 9 +Retrograde transport endosome to golgi 0.224870207344143 0.1748220756382853 0.8612194416103112 1.0 1.0 40 O60493,O43752,Q4KMP7,Q14203,P49257,O60271,Q9Y5X2,Q8IWJ2 8 +Negative regulation of leukocyte degranulation 0.4064965222937866 0.1747061664099658 0.8613105222047843 1.0 1.0 4 P30511 1 +L serine transport 0.497950605784044 0.1714286082033365 0.8638867616309052 1.0 1.0 3 Q9H9B4 1 +Positive regulation of production of mirnas involved in gene silencing by mirna 0.4048538334252691 0.1711256315539299 0.8641249820690322 1.0 1.0 4 Q02750,P04637,P17844 3 +Dendritic cell chemotaxis 0.4046161400037484 0.1706109898388472 0.8645296559888371 1.0 1.0 4 Q4KMQ2,P09429 2 +Regulation of receptor clustering 0.4966982520415942 0.1690578305594212 0.8657511537607032 1.0 1.0 3 Q15334 1 +Positive regulation of signaling receptor activity 0.3202588100251139 0.1678589416998268 0.8666942515068559 1.0 1.0 7 P78536 1 +Cellular response to alcohol 0.2531969633043289 0.1659835278985389 0.8681699131851688 1.0 1.0 18 Q6PKG0,Q9NS86,P20020,P54132,P11802 5 +Flavin containing compound metabolic process 0.4942883298516789 0.1645509926198034 0.8692974074741993 1.0 1.0 3 P55072 1 +Aspartate metabolic process 0.4942829593657796 0.1645410305093689 0.8693052492074871 1.0 1.0 3 P00505 1 +Nucleic acid phosphodiester bond hydrolysis 0.2242517081392709 0.164448709839741 0.8693779205720458 1.0 1.0 101 Q9GZR2,Q13283,Q14249,Q9BRX2,P54098,Q2NL82,P39748,Q96DE0,Q12972,Q15050,Q8IZD4,Q96QE3,Q92878,Q14137,Q6P2E9,Q9BQ61,P78316,Q8N9T8,Q9ULX3,Q86U38,Q96T60,Q92499,Q14692,P52758,P33240,Q6UN15 26 +Establishment of planar polarity of embryonic epithelium 0.4015604841078358 0.1640730028599893 0.8696736743738505 1.0 1.0 4 Q13308 1 +Response to ketone 0.2229844838521474 0.1639558040914756 0.8697659361245855 1.0 1.0 40 Q96ST3,Q01664,P09874,Q6PKG0,Q96EB6,Q13185,P20020,O75116,Q9H7B4,P61353,P40818 11 +Cellular response to osmotic stress 0.2772853710321846 0.1626946165729061 0.8707588858679309 1.0 1.0 12 O95747,P11166 2 +Regulation of hematopoietic progenitor cell differentiation 0.2812051897911679 0.1626757501219138 0.8707737412269652 1.0 1.0 11 P19525,O15047,Q92785,P38646 4 +Regulation of vesicle fusion 0.3699469305610189 0.1619977069635655 0.871307659597593 1.0 1.0 5 P04083,O60343 2 +Mitotic spindle midzone assembly 0.3697769043720675 0.1616102873107721 0.8716127557113948 1.0 1.0 5 Q9H0H5 1 +Cellular response to virus 0.2442078213205598 0.1613616164671789 0.8718085960830759 1.0 1.0 22 Q9NZM5 1 +Negative regulation of lipoprotein particle clearance 0.3691476000686348 0.1601808338217563 0.8727386268364823 1.0 1.0 5 P30533 1 +Dendritic spine morphogenesis 0.2607926649709829 0.1564997470089382 0.875639118643603 1.0 1.0 14 Q14444,Q9UJU6,Q9UQ16,Q9UQB8,Q96HC4 5 +Regulation of protein containing complex assembly 0.2327752898256378 0.1559569802347127 0.8760669310081435 1.0 1.0 112 P46821,Q9NWH9,P51608,P35611,Q71SY5,Q9NZM5,P16949,O75146,Q13813,Q14008,Q14247,P59998,P0DMV9,Q14203,Q9P270,Q14980,Q9NYL9,Q01082,P09874,P42345,Q16625,P51610,Q13112,P40429,P55072,P47755,Q9UQB8,P11142 28 +Leydig cell differentiation 0.4891862321881769 0.155250052192805 0.8766241906535994 1.0 1.0 3 Q15637 1 +Cell cycle phase transition 0.2689709349423188 0.1543278310852158 0.8773512541487836 1.0 1.0 163 Q96ST3,P04083,P51608,Q13123,P83731,O75179,Q9UNS1,Q14676,Q15398,Q9UN37,Q13564,Q96QC0,P12270,O60934,Q9NZM5,Q96QE3,P48681,P62753,P06748,P16104,Q7L2J0,Q9Y6D9,Q9H444,Q15910,P61254,Q01664,Q99459,Q86VI3,P54132,Q13769,Q9Y6A5,O00311,P54652,P78536 34 +Positive regulation of neuron death 0.2509748708396228 0.1535375048898893 0.8779744162967456 1.0 1.0 17 Q9UER7,P09874 2 +Positive regulation of protein kinase activity 0.2167027822139876 0.1532560399136062 0.8781963661301992 1.0 1.0 59 Q13177,Q9UER7,Q12802,Q15910,Q8IZP0,Q13432,P42345,Q9ULW0,P30040,Q96EB6,Q13043,P46940,P78536,Q99627,P08238,Q9H2P0,Q9NQS7 17 +Mitotic cell cycle phase transition 0.2496999313791237 0.1531793499030641 0.8782568418691383 1.0 1.0 134 Q96ST3,P04083,O60885,P51608,Q13123,P83731,O75179,Q15398,Q9UN37,Q13564,P12270,O60934,Q9NZM5,Q96QE3,P48681,P62753,Q7L2J0,Q9Y6D9,Q9H444,Q15910,P61254,Q01664,Q86VI3,Q99640,Q9NYL9,P54132,Q9Y6A5,O00311,P54652,P78536 30 +Central nervous system maturation 0.4815325248070415 0.1526977255663561 0.8786366544662214 1.0 1.0 2 P48444 1 +Receptor localization to synapse 0.2736347193347044 0.1511823741577846 0.879831853861486 1.0 1.0 12 P33176 1 +Regulation of wound healing spreading of epidermal cells 0.3643539840628315 0.1495239417166544 0.881140218962037 1.0 1.0 5 P42345 1 +Negative regulation of cell morphogenesis involved in differentiation 0.4853214084033223 0.1484225861584686 0.8820092763020315 1.0 1.0 3 Q9ULV4 1 +Regulation of endocytic recycling 0.485172795245942 0.1481638065026023 0.882213494732508 1.0 1.0 3 Q07960 1 +Epidermis morphogenesis 0.4790518191841089 0.1481232274564191 0.8822455187838842 1.0 1.0 2 O60568 1 +Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.3126064195474228 0.1480089366255831 0.8823357155173372 1.0 1.0 7 P26583 1 +Negative regulation of cell size 0.4849868150634366 0.1478403516491437 0.8824687632199142 1.0 1.0 3 P42345 1 +Positive regulation of cell morphogenesis involved in differentiation 0.2241129025945218 0.1460202273866805 0.8839054204286043 1.0 1.0 28 P60903,O75147,Q14444,Q9UJU6,P50570,Q9UQB8,P21333 7 +Inner ear receptor cell development 0.2923616386588658 0.1459622334252401 0.8839512024203087 1.0 1.0 8 O14745 1 +Biological process involved in symbiotic interaction 0.2080615368074358 0.1443243730838085 0.8852443328505821 1.0 1.0 86 Q9UQN3,Q9Y3E7,Q13573,P49790,Q9HD42,Q9UN37,Q15758,O60493,O75446,Q96JM3,Q86V81,Q96KP1,P0DMV9,Q9H444,Q01664,Q13769,P17980,Q9H1E3,P14373,P53990 20 +Striated muscle contraction 0.241669917498012 0.1417461960440632 0.8872804841442585 1.0 1.0 21 Q7Z406,P21333,P05026 3 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.3293926562066829 0.1406872047872161 0.888117053653952 1.0 1.0 6 Q9UII2,Q7Z6Z7 2 +Response to lipid 0.263058762042525 0.1403446954578108 0.8883876518834704 1.0 1.0 156 P23378,P46821,Q02952,P04083,Q14249,Q13573,Q14151,P09104,O95747,Q8TDD1,Q15648,Q9UBC1,P11802,P40818,Q9UER7,P82094,Q16576,O75528,O75592,Q96JM3,Q9NZZ3,P0DMV9,Q15910,P11274,Q01664,Q13308,Q13151,Q96EB6,Q13185,O75874,P61353,Q9GZZ9,Q15424,P26583,P09874,Q9NS86,P20020,P78536,O75116,Q9H7B4,O94788,P11142,P35573 43 +Golgi organization 0.2118626936578053 0.1402799446535613 0.8884388094799398 1.0 1.0 69 Q5T2E6,Q5VU43,Q9BSR8,Q92614,P49257,Q9UNZ2,Q9Y2V7,Q08379,Q8NCM8,Q9H8Y8,Q8IWJ2 11 +Positive regulation of cyclin dependent protein kinase activity 0.3890660146706618 0.1388544704785803 0.8895651496335841 1.0 1.0 4 P78536 1 +Positive regulation of neuroblast proliferation 0.4791838985387327 0.1379668552472026 0.8902666126731615 1.0 1.0 3 O60341,P26367 2 +Negative regulation of cell junction assembly 0.2829288713399543 0.1377907307676219 0.8904058102556671 1.0 1.0 9 O75116,Q13464 2 +Liver morphogenesis 0.3881373655675425 0.1370777939731252 0.8909693046060871 1.0 1.0 4 Q15648 1 +Positive regulation of inclusion body assembly 0.4780817369905061 0.1361394798906967 0.8917110176144352 1.0 1.0 3 P62195 1 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.2722526666736388 0.1359779502956055 0.891838712158376 1.0 1.0 11 P11940,Q9NZI8,Q00839 3 +Coronary vasculature morphogenesis 0.4778330502164998 0.13572927334477 0.8920353050815164 1.0 1.0 3 O95487 1 +Coronary artery morphogenesis 0.4778330502164998 0.13572927334477 0.8920353050815164 1.0 1.0 3 O95487 1 +Placenta development 0.2321295187152666 0.1344672315386778 0.8930331211734432 1.0 1.0 24 Q96T37,Q13263,O75190,Q04721,Q12830,Q9Y3I0,Q13043,Q15648,P08238,Q9NR09,P62993,P62753 12 +Response to virus 0.2143425444802593 0.1340179371034046 0.8933883906299775 1.0 1.0 94 Q96ST3,Q13283,Q9Y3E7,O60858,Q9NUQ8,Q9UHR5,Q9Y4E8,O75179,Q13049,Q9NR30,Q9NZI8,Q9NZM5,P16949,Q9NV70,Q12906,P06733,P35269,Q9NY93,Q9H078,Q7Z434,O14802,P14373,Q92499,Q53F19,O60828 25 +Regulation of nucleotide biosynthetic process 0.2743773100270995 0.1329547637847233 0.8942291560657742 1.0 1.0 10 P27144,P09874 2 +Aminoacyl trna metabolism involved in translational fidelity 0.2738812319612344 0.1316059452553373 0.8952959827993798 1.0 1.0 10 Q9BTE6,P26640,Q15031,Q5ST30 4 +Response to atp 0.4750094149268657 0.1311262802688657 0.895675412002169 1.0 1.0 3 Q96GD0 1 +Ras protein signal transduction 0.202978108003059 0.1308620917244072 0.8958844031587183 1.0 1.0 78 Q13464,Q13283,Q9NWH9,P46108,Q92974,P62993,Q8N6T3,P40818,O75955,Q12802,P35241,Q92888,Q04721,P16949,Q9UJU6,Q5VZ89,Q15555,P50570,P42771,P11274,P84095,P26358,Q86VI3,Q9Y6W5,Q07960,Q9UN86,O75116 27 +Regulation of protein maturation 0.2667029129788622 0.1305959853505178 0.8960949187534004 1.0 1.0 12 Q9Y366 1 +Cytokine production involved in inflammatory response 0.2799010805352694 0.1298516746974929 0.8966837784762756 1.0 1.0 9 Q15910 1 +Dna modification 0.2192872720172511 0.1287323709656671 0.8975694201925681 1.0 1.0 34 Q9NRZ9,Q15910,P09874,Q9NPF5,P26358,P51608,Q86YP4,O94776 8 +Response to type i interferon 0.2443770738424774 0.1287164856854148 0.8975819902371371 1.0 1.0 15 Q7Z434,Q16543,Q9NZI8 3 +Positive regulation of cell projection organization 0.2066250193773882 0.1283933122958706 0.8978377233699943 1.0 1.0 74 P46821,Q9UHD8,Q32P28,O60493,O75147,Q9ULV4,Q14444,Q9UJU6,Q9NQW6,Q15555,P50570,Q15910,Q9NY93,Q13308,Q9H4M9,Q9Y6W5,Q9H2P0,P42345,Q16625,Q9ULH0,Q9UQ16,P53990,Q9UQB8,P21333,Q06787 25 +Positive regulation of histone ubiquitination 0.3541469803563584 0.1282048634708208 0.8979868513409501 1.0 1.0 5 O75150 1 +Membrane docking 0.2199430793358791 0.12809957869519 0.8980701694548072 1.0 1.0 32 O60493,O43752,Q13464,P15311,O15078 5 +Regulation of epithelial to mesenchymal transition 0.2791977220625386 0.1280458825507958 0.8981126628448326 1.0 1.0 9 Q15910 1 +Leukocyte mediated cytotoxicity 0.2425741345128636 0.1279305473742616 0.8982039363566474 1.0 1.0 18 Q9BY67,P30511 2 +B cell lineage commitment 0.4666482910694446 0.1265935675646888 0.8992620883193436 1.0 1.0 2 P04637 1 +Positive regulation of endothelial cell proliferation 0.2651950546557037 0.1263396559205636 0.8994630668503611 1.0 1.0 12 P26583 1 +Histone phosphorylation 0.2326076141934736 0.1251375121730723 0.900414686274722 1.0 1.0 23 Q9UIG0,O60264,Q13043,Q06787,Q99986,O75367,Q9Y4B6,Q05655,Q9NQS7 9 +Humoral immune response mediated by circulating immunoglobulin 0.4709125999448535 0.1246259065393109 0.9008197178378184 1.0 1.0 3 Q07021,Q9UQ84 2 +Anatomical structure formation involved in morphogenesis 0.2775749910616106 0.1243356139867425 0.9010495501879124 1.0 1.0 186 Q9Y281,Q13464,P04083,Q8IZP0,Q9Y2J2,P55011,P51608,O95747,Q05682,Q15648,Q92541,O15078,P07942,Q9UII2,Q12802,Q07157,P82094,O75147,O75175,Q4VCS5,Q04721,Q96JM3,Q13043,Q16881,Q5JRA6,O95487,Q96T37,P19338,Q13308,Q9H4M9,P04920,Q96EB6,Q9UGM6,P62081,O14964,Q9NYL9,P35579,Q15149,Q13428,Q9Y366,Q14978,Q14315,P78536,P25440,O96013,P21333,O94788,Q8N3R9 48 +Metaphase anaphase transition of cell cycle 0.2194774684516686 0.124323345699772 0.9010592635004906 1.0 1.0 30 Q15398,Q13123,P12270,Q9Y6D9 4 +Meiosis i cell cycle process 0.2412632496929238 0.1236148464167273 0.9016202369097466 1.0 1.0 18 Q92878 1 +Positive regulation of phagocytosis 0.2677092367783281 0.1234410010465355 0.9017578911862688 1.0 1.0 11 P11274,Q92614,Q9NX58,Q4KMQ2,P50570 5 +Fatty acid beta oxidation using acyl coa dehydrogenase 0.2829928216455013 0.1223676741231562 0.9026078383946988 1.0 1.0 8 P13804,P49748,P11310,P16219,Q92947,Q16134,P38117 7 +Peptidyl threonine modification 0.217343629905496 0.1221885906420565 0.9027496620961516 1.0 1.0 35 O95747,Q05682,Q13464,Q9Y5S2 4 +Ires dependent viral translational initiation 0.2634833187514146 0.1216040134902686 0.9032126347769158 1.0 1.0 12 P26599,P41214 2 +Regulation of dendrite morphogenesis 0.2418913714558619 0.1213340395253963 0.903426459538853 1.0 1.0 16 Q9UQB8,O60828,O75147,Q6SZW1 4 +Negative regulation of cellular amide metabolic process 0.209056131557963 0.1213109652131764 0.9034447351792304 1.0 1.0 90 Q13464,P11940,O75175,P12270,Q9UKZ1,Q9Y6M1,Q6PKG0,P19338,P00374,O75298,Q13526,Q12906,Q8IZD4,P40429,Q92945,Q9NZI8 16 +Positive regulation of protein secretion 0.2185939193312497 0.1203784237217237 0.9041833824766444 1.0 1.0 30 P80404,Q12846,Q92614,O00233,Q9Y5K6,P15311,P22059,P35580 8 +Positive regulation of neurogenesis 0.2135563600635441 0.1200205413339342 0.904466875947098 1.0 1.0 44 O75147,P42345,Q13573,Q9UQB8,Q14444,P53990,Q13049,Q9H2P0 8 +Extrinsic apoptotic signaling pathway via death domain receptors 0.2409331160333795 0.1184073041021001 0.9057449386576152 1.0 1.0 16 Q9UER7,Q13043,P26583,Q92974 4 +Hydrogen peroxide catabolic process 0.3775510204081684 0.1177820833767451 0.9062403261161548 1.0 1.0 4 P32119,P30048,Q13162 3 +Positive regulation of viral process 0.2179593529236084 0.1175831928277408 0.906397922733317 1.0 1.0 30 Q96T23,P11940,Q16513,O95793,Q6PKG0 5 +Regulation of dna demethylation 0.4662255307416552 0.1174469014891582 0.906505919203533 1.0 1.0 3 Q13263,Q93008 2 +Serine transport 0.3771302453320203 0.1170515068355886 0.9068192374206108 1.0 1.0 4 Q9H9B4 1 +Regulation of cyclin dependent protein kinase activity 0.2348468636544827 0.1169079141681941 0.9069330265635936 1.0 1.0 21 Q96SN8,Q01664,Q99640,Q16543,P54132,P78536,P08238,O94992,P32780 9 +Modification of synaptic structure 0.2993492897838684 0.1169075706321846 0.9069332987989231 1.0 1.0 7 O95793 1 +Positive regulation of protein phosphorylation 0.2295601984618898 0.1162165322128816 0.9074809347227656 1.0 1.0 114 Q8IZP0,Q96N67,P46940,Q99627,Q92974,Q13177,Q9UER7,Q12802,O60934,Q13526,Q96JM3,Q13043,Q9NYB0,Q92878,Q9NQS7,O00165,Q15910,P30040,Q86VI3,Q96EB6,Q9ULW0,P08238,Q7Z434,Q9H2P0,Q13432,Q9H223,P42345,P54652,P22059,P67870,P78536,O75116,Q9H7B4 33 +Calcium ion export 0.3476575541769296 0.1156257716230443 0.90794913709337 1.0 1.0 5 P0DP25,P20020 2 +Intracellular distribution of mitochondria 0.4594818081587496 0.1151679370317378 0.9083120120802805 1.0 1.0 2 O75153 1 +Regulation of protein polyubiquitination 0.2740028465456602 0.1151578348134107 0.9083200192106288 1.0 1.0 9 O95071,O75150,P61088 3 +Regulation of histone h2b ubiquitination 0.3757656602627776 0.1147013214072558 0.9086818665113744 1.0 1.0 4 Q5VTR2,O75150 2 +Modulation by host of viral genome replication 0.2979958913619489 0.1139680758911289 0.9092631002653492 1.0 1.0 7 P11142,Q9H1E3 2 +Chromatin remodeling at centromere 0.3463103290390189 0.1131093386320096 0.9099438713507716 1.0 1.0 5 Q7Z7K6,Q9NRZ9,P84243 3 +Positive regulation of telomere capping 0.3457116729179582 0.1120016019210268 0.9108221364149848 1.0 1.0 5 P27361,P28482,Q96T60 3 +Regulation of type i interferon mediated signaling pathway 0.2532357935730329 0.1117822860136468 0.9109960331996592 1.0 1.0 13 Q7Z434,Q16543,Q9NZI8 3 +Positive regulation of cilium assembly 0.2782518510002551 0.1113433416301762 0.9113440874030896 1.0 1.0 8 Q9UHD8 1 +Negative regulation of exocytosis 0.2660122230919527 0.1112478840487765 0.911419781279571 1.0 1.0 10 P30511,P04083 2 +Response to nitrosative stress 0.3156732891832196 0.1108958848530698 0.9116989088868924 1.0 1.0 6 Q99497,P48506,P48507,P31689,P11766 5 +Establishment of organelle localization 0.255479124426374 0.1107789350433183 0.9117916499226544 1.0 1.0 150 P46821,Q9UQN3,Q9Y3E7,Q8TD16,Q99661,Q96N67,Q9HD42,Q15398,O95219,Q9UN37,P33176,Q13561,Q66K74,Q92572,O15027,P62841,Q15050,Q96JM3,P15311,P50570,Q9NVU7,Q86VS8,Q9NZZ3,Q9NQS7,O94832,O43795,P06748,O14745,P51809,Q9H444,Q9Y6D9,Q00839,Q14203,Q7Z460,Q9UM54,P27816,Q14980,Q9UNZ2,O95721,Q14807,O14964,P35579,Q86U38,Q8WXW3,Q9Y496,Q9HC35,Q96GA3,O00159,Q96EE3 49 +Inositol lipid mediated signaling 0.237794201227493 0.1102155717324856 0.912238413053312 1.0 1.0 17 O14745,Q9NZM5,P15311,Q96EB6,O00165 5 +Regulation of dna binding transcription factor activity 0.2023380116694267 0.1100652900477646 0.9123575953970142 1.0 1.0 76 P06748,P0DMV9,Q15910,Q9UBC1,Q7Z434,O60858,Q99496,P21333,P14373,O60826,Q9NXV6,P61088,Q13049,Q92974,Q9NYB0 15 +Hippocampus development 0.2344768127352327 0.1100499395427586 0.9123697693745032 1.0 1.0 20 P18887 1 +Telomerase rna localization 0.2379634753735462 0.109600205631733 0.912726447570962 1.0 1.0 16 P50991,Q01780,Q96HR8,Q9Y230,Q9NPE3,O60832,O95453,P40227,Q99832,P78371,P48643,P49368,P17987,Q9NX24,P50990 15 +Regulation of cytoplasmic mrna processing body assembly 0.4547960308709892 0.1080942935681742 0.9139208947050784 1.0 1.0 2 Q9HBH5 1 +Negative regulation of nuclear division 0.2321630992149023 0.1078408111301102 0.9141219690452552 1.0 1.0 21 P12270,Q9Y6D9 2 +Positive regulation of vasculature development 0.2337846657333623 0.1078240678860692 0.9141352507773703 1.0 1.0 20 O96013,Q9UGM6,Q07157,Q96JM3 4 +Vacuolar localization 0.2361962158646568 0.1077182816218973 0.9142191672572104 1.0 1.0 18 P35579,O60271,P33176,P51809 4 +Cell cell adhesion via plasma membrane adhesion molecules 0.2318002995888768 0.1066454553992818 0.9150702559953772 1.0 1.0 21 Q9BY67,Q13740,O75147,P10586,P19022,Q9Y639,Q8WX93,O60245,O00192 9 +Positive regulation of binding 0.2091757543150689 0.105897701755268 0.9156635175493903 1.0 1.0 58 Q9NWH9,O60869,P17301,P62913,P35611,O75955,Q71SY5,Q13526,P16949,O75146,Q13043,P19474,P26367,P62942,P07305,Q13263,P08238,P0DP25,P18074,P26583,P60903,P09874,Q06787 23 +Negative regulation of transferase activity 0.2070714600832913 0.1035860530375557 0.9174978561800178 1.0 1.0 68 Q96SN8,Q12834,O95816,P13861,P62913,P49593,Q13177,Q9ULV4,P62841,P31689,Q00839,P06748,P42771,Q01664,Q96EB6,P62081,P46777,Q15149,Q53EL6,Q13257,P14373,O75367,Q9H7B4,O94992,Q05655 25 +Neuromuscular junction development 0.2598715216271516 0.1034197965117265 0.917629801045603 1.0 1.0 11 Q14203,P11047 2 +Protein localization to chromatin 0.2350549767190076 0.10223097768415 0.9185733399237628 1.0 1.0 17 Q15910,Q8NC56,Q8NEY8,Q9P0M6,P55072 5 +Alpha amino acid metabolic process 0.1992426620109241 0.1021476077556134 0.9186395130873276 1.0 1.0 78 P23378,P00374,P51608,Q05682,Q9ULX3 5 +Negative regulation of phosphatase activity 0.2593084923025038 0.1020596094626615 0.9187093605311368 1.0 1.0 11 O75116,Q13464 2 +Establishment of planar polarity involved in neural tube closure 0.4551555711496735 0.1015761256760188 0.9190931303641388 1.0 1.0 3 Q13308 1 +Proximal tubule development 0.454585930179196 0.1008003406959769 0.9197089563834636 1.0 1.0 3 Q04721 1 +Response to growth factor 0.2290455847835245 0.1000256542123135 0.9203239584622064 1.0 1.0 116 P46821,Q13464,P04083,Q8NC56,Q9BRX2,Q13573,Q9Y4E8,P46940,Q15648,P50402,P40818,Q13177,Q9Y448,P12270,Q13526,Q04721,Q15942,Q9Y2U8,O14737,P62942,P19338,Q14980,Q9H4M9,Q96EB6,O14964,P08238,O00159,P09874,Q9H223,O75116,O43237,P78536,P33240,Q9UQB8,Q8N3R9 35 +Regulation of protein folding 0.3389736961088072 0.0999771069552401 0.9203625003716184 1.0 1.0 5 O14737 1 +Response to amine 0.2728102123370632 0.0994457261379957 0.9207843784618368 1.0 1.0 8 P23378,P0DP25,Q7LG56 3 +Mesodermal cell differentiation 0.4487320837927073 0.0994005613659162 0.9208202370670008 1.0 1.0 2 P17301 1 +Positive regulation of dna binding transcription factor activity 0.2068779076852479 0.098923928387485 0.9211986699827496 1.0 1.0 48 P06748,P0DMV9,Q7Z434,O60858,P14373,P61088,Q13049,Q92974 8 +Neural tube formation 0.2294005558106994 0.0989203106428509 0.921201542436578 1.0 1.0 21 Q13308,Q9Y366,P62081,P25440,O95487 5 +Regulation of signaling receptor activity 0.2341665699836441 0.0989163969926499 0.9212046498376876 1.0 1.0 16 P30533 1 +Nitric oxide mediated signal transduction 0.4481808158765 0.0986357478038291 0.9214274857628144 1.0 1.0 2 P23634 1 +Calcium ion regulated exocytosis 0.2604849723884073 0.0981128657125059 0.9218426714569106 1.0 1.0 10 P35579,Q15042,P51809 3 +Phosphatidylinositol 3 kinase signaling 0.2542133484131253 0.0977311419521234 0.9221457862196089 1.0 1.0 12 Q9NZM5 1 +Mirna loading onto risc involved in gene silencing by mirna 0.4516129032258017 0.0968158097054243 0.9228726685868632 1.0 1.0 3 O75569,P55265 2 +Negative regulation of organic acid transport 0.3369562959686114 0.096534711653921 0.9230959067365154 1.0 1.0 5 P80404,O75915 2 +Positive regulation of amino acid transport 0.3365769586872988 0.0958955182593107 0.9236035540881776 1.0 1.0 5 P55011,Q15042 2 +Positive regulation of amine transport 0.3365769586872988 0.0958955182593107 0.9236035540881776 1.0 1.0 5 P55011,Q15042 2 +Epithelial cell cell adhesion 0.3360399551268563 0.0949950243803887 0.9243187790185384 1.0 1.0 5 P18206 1 +Glutathione metabolic process 0.2295441167933608 0.0947348865923043 0.9245254070876328 1.0 1.0 20 O75874 1 +Negative regulation of histone modification 0.22950714610544 0.0946248970093389 0.924612773609728 1.0 1.0 20 Q96ST3,P26358,Q96EB6,Q12824,O75367,O95071,Q7KZ85 7 +Response to ionizing radiation 0.2090807856965047 0.0944818316694574 0.9247264141061452 1.0 1.0 39 P16104,P04083,P09874,P61254,O60858,Q9H1E3,P54132 7 +Ncrna metabolic process 0.2958344193930629 0.0938582167881023 0.9252217854322468 1.0 1.0 298 Q9GZR2,Q2NL82,Q9Y3B9,Q9HC36,Q9P2D1,Q9NZM5,P62841,O43290,Q7L2J0,Q8IY81,P62424,Q9NPE3,Q99848,P78316,P62081,Q9ULX3,Q5ST30,Q9H9Y2,Q13428,Q8N201,Q9Y2W2,Q8NEF9,Q9Y5Q8,Q9BSC4,O60832,Q9Y237,Q8TDD1,Q9NR30,O43709,Q15050,P82912,P61254,P19338,Q76FK4,Q969X6,O43818,Q9BQ61,Q9UGM6,Q9NSI2,Q9H501,Q5JTH9,P61353,P05455,P62263,O00566,Q14978,Q14692,O94992,Q9BRX2,Q14331,P62913,P46087,O15160,P50914,Q96DE0,Q8WUA4,Q9H6R4,Q9BVJ6,Q9BTE6,Q14137,Q14690,Q9NY93,Q8N9T8,P62857,P39019,Q86U38,Q12849,Q8WWH5,P55769,Q9Y3I0,Q8N1G4,Q15031,O75691,P62847,Q8WVM0,Q9BXP5,Q9NV06,Q92945,Q8IY37,P07814,Q9H9T3,Q2VPK5,Q99547,Q96GQ7,Q6P1N0,O15213,P62753,P46777,Q9H3H1,Q9H0H0,Q96FX7,P42345,Q92499,Q9P0M6 94 +Regulation of skeletal muscle cell differentiation 0.3618312189740789 0.0923640507332151 0.9264088006571396 1.0 1.0 4 Q9BRT2,Q9BYT8,P17844 3 +Pyrimidine deoxyribonucleoside monophosphate biosynthetic process 0.4480286738351205 0.0921550663596277 0.926574837915998 1.0 1.0 3 P04818,P33316 2 +Dtmp metabolic process 0.4480286738351205 0.0921550663596277 0.926574837915998 1.0 1.0 3 P04818,P33316 2 +Pyrimidine deoxyribonucleoside monophosphate metabolic process 0.4480286738351205 0.0921550663596277 0.926574837915998 1.0 1.0 3 P04818,P33316 2 +Calcium ion export across plasma membrane 0.4473347648408098 0.0912706971128604 0.9272775010996236 1.0 1.0 3 P20020 1 +Spinal cord development 0.238182314538687 0.0908361292456955 0.9276228017217324 1.0 1.0 14 Q8NCM8 1 +Positive regulation of telomerase rna localization to cajal body 0.2381329023639108 0.0907150439834761 0.927719016550124 1.0 1.0 14 P50991,Q9NPE3,O60832,P78371 4 +Intracellular mrna localization 0.4421168687982237 0.0905003308113524 0.9278896310838474 1.0 1.0 2 Q99729 1 +Mrna cleavage 0.2568905700019935 0.0900832224156793 0.9282210815805912 1.0 1.0 10 Q9P2I0,Q6UN15,P33240,Q8N684 4 +Succinate metabolic process 0.3596249310535063 0.0891025094122616 0.9290004431068644 1.0 1.0 4 P21912,P51649,P31040 3 +S adenosylmethionine metabolic process 0.3321699298417174 0.0886565023143499 0.9293549024751172 1.0 1.0 5 P31153,Q9NZL9 2 +Neutral amino acid transport 0.3035502706478638 0.0878526027979452 0.9299938283650058 1.0 1.0 6 Q9H9B4 1 +Cell surface receptor signaling pathway involved in cell cell signaling 0.200734440050278 0.0870340371927133 0.9306444569823448 1.0 1.0 86 O60493,O14745,Q13283,Q13308,P51608,Q8NBM4,P19022,Q9HCK8,Q92541,P40818 10 +Positive regulation of exosomal secretion 0.2611521204649132 0.0866600394327534 0.9309417407845502 1.0 1.0 9 O14964 1 +Regulation of complement activation 0.4433416046319232 0.0862939193283628 0.9312327721194592 1.0 1.0 3 P35232,Q07021 2 +Regulation of humoral immune response 0.4433416046319232 0.0862939193283628 0.9312327721194592 1.0 1.0 3 P35232,Q07021 2 +Nuclear transport 0.2526578359490969 0.0855893483673734 0.9317928661583366 1.0 1.0 151 O75152,Q9UKX7,Q9NPF5,P49790,Q15648,Q12802,P12270,Q96QC0,Q6P6C2,P62841,O14974,P55735,Q9H814,Q9NVU7,Q86V81,P35658,P06748,Q9HAU5,Q9NPA8,Q9BY77,P02545,Q7Z434,Q86U38,Q8NFH5,P82979,Q9H7Z3,Q96GA3,Q9BZI7,Q14978,Q53F19,P21333 31 +Positive regulation of leukocyte chemotaxis 0.2355559978928798 0.0845334557908298 0.9326323041517912 1.0 1.0 14 P78536 1 +Pyrimidine containing compound metabolic process 0.2097644105084491 0.0845314977762825 0.932633860849542 1.0 1.0 31 P42345,Q05682,P27144,Q9UIJ7 4 +Cell cell adhesion 0.2275798703370735 0.0838228498633792 0.9331972803881854 1.0 1.0 117 Q9BY67,Q13464,P04083,P10809,P10586,P35221,O00151,Q96HC4,P26038,O00192,O75955,P07942,P18206,Q13740,O75147,P35241,Q07157,P49593,P80404,Q9Y5K6,P15311,P19022,Q5JRA6,Q9Y639,Q8WX93,O43290,P12814,Q9Y490,Q9Y6D9,Q96IZ0,Q96EY1,Q9NYL9,Q14126,P35579,O60245,P78540,Q9UDY2,O96013,O75190,Q96JJ3,P55196,Q14168,Q9UQB8,Q13630,P21333,Q05655 46 +Glycerol ether metabolic process 0.2825895961229733 0.0835644506681892 0.9334027322974472 1.0 1.0 7 Q6PIU2 1 +Regulation of cellular response to stress 0.2648221149435013 0.0827063342216188 0.9340850481510208 1.0 1.0 172 Q15014,Q14249,Q9NWH9,Q04323,Q9NPF5,P00374,P10586,Q99543,O75915,P18887,Q9UNS1,Q13049,Q92974,Q9Y4L1,Q15233,Q7Z3K3,Q96QC0,Q9HAF1,P15311,P31689,P25685,Q7Z4V5,Q9UMX0,P61088,Q9NYB0,Q96QE3,P06748,P16104,P23246,P61254,P30040,Q96EB6,Q13769,Q9NYF8,Q96T60,P78540,P09874,Q9BW85,P42345,O75190,Q969S3,P21333,Q15906 43 +Positive regulation of rig i signaling pathway 0.4400682033395134 0.0823560077616067 0.9343636178817942 1.0 1.0 3 O75179 1 +Regulation of endodeoxyribonuclease activity 0.300213885340347 0.082046124411913 0.9346100350908336 1.0 1.0 6 P06748,Q05655,Q96EB6 3 +Response to acid chemical 0.2250917222033931 0.0819972930941033 0.9346488660067888 1.0 1.0 20 P42345,Q15149,Q9UQB8 3 +Ether metabolic process 0.2587017085270783 0.0817669691419387 0.9348320228969929 1.0 1.0 9 Q6IAN0,Q6PIU2 2 +Negative regulation of dna damage checkpoint 0.3276865162877252 0.0816430389242183 0.9349305754008012 1.0 1.0 5 Q96QC0 1 +Negative regulation of cell cycle checkpoint 0.3276865162877251 0.081643038924218 0.9349305754008016 1.0 1.0 5 Q96QC0 1 +Pancreatic juice secretion 0.4327453142226997 0.0789111507895289 0.9371032938540922 1.0 1.0 2 Q9H4A3 1 +Regulation of dendritic spine development 0.2330939277024858 0.0788699051626139 0.937136100853282 1.0 1.0 14 Q14444,Q9UJU6,Q9UQ16,Q9BRT6,Q9UQB8 5 +Protein localization to condensed chromosome 0.2455085360399091 0.0780120326028902 0.9378184815311048 1.0 1.0 12 Q96JM3 1 +Smooth muscle cell apoptotic process 0.2566630934162229 0.0778262267576892 0.937966283781754 1.0 1.0 9 P26358,P98175,Q53EL6,Q96EB6 4 +Positive regulation of cell development 0.2038400639472311 0.0777995447235024 0.93798750861099 1.0 1.0 65 P46821,O75147,P60903,P46108,Q9BXP5,P42345,Q13573,Q9UQB8,Q14444,Q9UJU6,P35611,P50570,Q9Y639,P53990,Q13049,P21333,Q9H2P0 17 +Hormone transport 0.2049581116738733 0.0774358007026518 0.9382768614301766 1.0 1.0 42 Q12846,Q9P2D1,P04083,P82094,O00233,Q6WKZ4,Q8N183,P22059,O95219,Q12904,P51809 11 +Intra golgi vesicle mediated transport 0.2231202991314957 0.076682246578236 0.9388763281282596 1.0 1.0 20 Q9Y2V7 1 +Aldehyde catabolic process 0.2969094922737284 0.0765202739106486 0.939005185013548 1.0 1.0 6 Q96GD0,Q99497,P14550,P11766,P10768 5 +Cell cycle g1 s phase transition 0.2033256506205314 0.0763845708808359 0.9391131443944936 1.0 1.0 66 Q7L2J0,P04083,P35241,Q8N6R0,Q15910,P18754,O60885,P61254,Q6P1J9,Q86VI3,O00311,Q8N7H5,Q07666,O75179,Q13620,P78536,P11802,P62753 18 +Phagocytosis 0.2019862336049932 0.0755705992770232 0.939760727934026 1.0 1.0 48 O60493,P04083,P11274,Q92614,Q9NWH9,P84095,Q9ULV4,Q9NT62,Q96JJ3,Q9NX58,Q4KMQ2,P50570,Q8NBS9,P35579,P51809 15 +Regulation of camp dependent protein kinase activity 0.2962242993985586 0.0754022899475611 0.939894637283921 1.0 1.0 6 Q13043,P13861,Q96EB6 3 +Regulation of protein k63 linked ubiquitination 0.2775668135280718 0.0748514865200059 0.9403328763611224 1.0 1.0 7 O95071,P61088 2 +Regulation of anatomical structure morphogenesis 0.2583409199205329 0.0735397879706577 0.941376583549974 1.0 1.0 163 P46821,Q13464,P04083,Q96HS1,Q9Y2J2,P55011,P51608,O60271,Q5VSL9,Q9NZM3,O95747,Q7Z406,Q7Z6Z7,Q6SZW1,Q96HC4,Q13177,O75147,Q07157,O75400,Q4VCS5,Q14444,P15311,Q96JM3,P19022,O95487,O14745,P11274,P84095,Q13308,Q96EB6,Q9UGM6,O14964,P35580,P35579,Q9H2P0,Q9GZY8,O60610,Q9UEE9,O96013,O60828,O75116,P53990,Q9UQB8,Q5VZL5,P21333 45 +Regulation of neurogenesis 0.2029743577759393 0.0730030366571365 0.9418037010578316 1.0 1.0 65 Q9P2D1,O75147,Q15910,P26583,P42345,Q13573,Q9UQB8,Q96N67,P53990,Q13049,Q86VS8,Q9H2P0 12 +N glycan processing 0.3216603811078264 0.0727671675636253 0.941991398156954 1.0 1.0 5 P33908,P14314 2 +Sno s rna processing 0.2480662983425331 0.0720575832447766 0.9425560821004596 1.0 1.0 10 Q13868,Q01780,O60832,Q5RKV6,Q4G0J3,Q9NQT4,P22087,Q9NQT5,Q9NPD3 9 +Interferon gamma production 0.2535420328254577 0.072019831810853 0.9425861253297052 1.0 1.0 9 P14373,P10809,Q01650 3 +Negative regulation of cell adhesion 0.2046002891996952 0.0718013872676554 0.9427599687921095 1.0 1.0 36 P80404,P42771,P04083,P35241,Q9Y6D9,P78540,Q96IZ0,Q9ULV4,Q5JRA6,Q05655,P49593 11 +Regulation of dna damage checkpoint 0.2740844958603985 0.0691494101994129 0.9448706914699108 1.0 1.0 7 Q96QC0 1 +Cytoplasmic sequestering of transcription factor 0.2917670753448745 0.0683612642133288 0.9454980563439406 1.0 1.0 6 O60826 1 +Vesicle cargo loading 0.2282089364117756 0.0683246627676848 0.9455271919500852 1.0 1.0 14 P55735,Q15437,Q5JRA6,O95487 4 +Positive regulation of dendrite morphogenesis 0.2459950152866734 0.068168321527005 0.9456516440513444 1.0 1.0 10 Q9UQB8,O75147,Q14444 3 +Hematopoietic progenitor cell differentiation 0.205207766862599 0.0681065869209071 0.9457007869297668 1.0 1.0 30 Q96ST3,P18074,O15047,Q15050,Q9NQW6,Q92785,Q9Y520,Q9Y3A5,P38646 9 +Positive regulation of organelle assembly 0.2051189965625143 0.0680765657412792 0.9457246849001972 1.0 1.0 29 Q13283,Q14980,Q9UHD8,Q15555,Q9UN86,O95219,Q15042 7 +Positive regulation of mirna mediated gene silencing by inhibition of translation 0.3439051296194153 0.0679900851866624 0.9457935268962808 1.0 1.0 4 O60573,P26196,Q04637 3 +Cardiac muscle cell action potential 0.2405036702980562 0.0678327444778597 0.9459187774599112 1.0 1.0 12 P05026 1 +Positive regulation of mitochondrial membrane potential 0.3427057698065981 0.0665294147257076 0.9469563400154336 1.0 1.0 4 P55072 1 +Protein localization to chromosome centromeric region 0.2337901884249206 0.0665154168635425 0.9469674840088635 1.0 1.0 13 Q96JM3 1 +Regulation of cilium assembly 0.2189603703738606 0.0661104952014119 0.9472898551706388 1.0 1.0 20 Q4KMP7,P27816,Q9NT62,Q9UHD8,Q15555 5 +Retinal metabolic process 0.3168071928011805 0.0660710934137137 0.947321224662978 1.0 1.0 5 Q6UX07 1 +Nucleolar chromatin organization 0.290177133036825 0.0659460506374736 0.947420777245248 1.0 1.0 6 O75367,Q96EB6 2 +Telencephalon regionalization 0.4208930540242387 0.0659061240438571 0.9474525649042048 1.0 1.0 2 P26367 1 +Cerebral cortex regionalization 0.4208930540242387 0.0659061240438571 0.9474525649042048 1.0 1.0 2 P26367 1 +Forebrain regionalization 0.4208930540242387 0.0659061240438571 0.9474525649042048 1.0 1.0 2 P26367 1 +Positive regulation of actin cytoskeleton reorganization 0.2901089454643754 0.0658435952316756 0.94750234754496 1.0 1.0 6 Q9UQB8 1 +Negative regulation of intrinsic apoptotic signaling pathway 0.2011977938443417 0.0644598144693918 0.9486041039425536 1.0 1.0 38 Q9NRZ9,O95881,P31689,Q96EB6,P06733,Q13049,Q92974,Q96QE3,Q9Y4L1,Q15233 10 +Nuclear transcribed mrna catabolic process nonsense mediated decay 0.2180738163869157 0.0639688954838314 0.9489949938723898 1.0 1.0 20 Q9BZI7,Q8IZD4,P11940,Q9HAU5 4 +Positive regulation of proteolysis 0.2091964878553358 0.063342236380013 0.9494939835025183 1.0 1.0 99 Q12834,O75150,O75915,P61604,Q13049,Q6ZXV5,Q9UII2,Q9NZM5,O75146,P61956,Q9UMX0,O14737,P0DMV9,Q01664,O00291,O60826,P35579,P17980,Q9UKS6,P53990 20 +Antiviral innate immune response 0.3144827586206934 0.0630046636988015 0.9497627906071168 1.0 1.0 5 P35232,Q92667,Q9H078,Q99623 4 +Positive regulation of secretion 0.2012354060967788 0.0620232727054023 0.9505442987392332 1.0 1.0 61 P80404,Q12846,P82094,Q92614,Q12904,P55011,O00233,Q9Y5K6,Q9NV70,P15311,O14964,P30511,P22059,P35580,O95219,Q15042,Q9UN37,P51809 18 +Regulation of nitric oxide metabolic process 0.2373901572072826 0.0619170351012096 0.950628901477345 1.0 1.0 12 O75116,P50570,Q92945,P08238,P04179,P07900 6 +Cellular response to molecule of bacterial origin 0.2026113192374163 0.0614232553940648 0.9510221321978176 1.0 1.0 27 P11802,P26583,P11274,Q53EL6,Q6P1J9,Q96JM3,Q9UBC1,Q9NZZ3 8 +Pyrimidine nucleotide metabolic process 0.2159126214223996 0.0612700396258961 0.9511441508742092 1.0 1.0 21 Q05682,P27144 2 +Gamete generation 0.2249279239265222 0.060996013886959 0.9513623836038404 1.0 1.0 118 Q9BY67,Q9UPN4,Q9H0H5,Q9P0K7,P82094,Q6P6C2,P68402,Q14141,Q96PU8,Q01085,P25490,P62753,P16104,Q99496,P04920,Q15019,Q9H8Y8,Q9C0J8,P26583,P42345,P54652,Q9UHI6,P14373,P25440 24 +Postsynapse organization 0.2023631953002951 0.0607560318634944 0.951553507085156 1.0 1.0 34 P11142,Q14444,Q9UJU6,Q9UQ16,Q96EY1,P19022,Q9Y6W5,Q15334,Q9UQB8,Q96HC4,Q14247,P12814 12 +Dna repair 0.2705512831961508 0.0601367955534193 0.9520466843671804 1.0 1.0 190 Q9GZR2,Q15014,Q14683,Q9NPF5,P54098,Q7Z6Z7,P20585,P18887,Q14676,Q9UNS1,P39748,Q15233,Q9HAF1,P25205,O60934,Q9NZM5,Q7Z4V5,Q9H981,P61088,Q92878,P25490,P06748,Q9Y2K7,P16104,P23246,Q9UQE7,Q99459,Q13111,P33991,Q9C0J8,Q96T60,P26583,P09874,O00311,P49916,Q9H1E3,Q92499,Q13112,Q15906 39 +Dna double strand break processing 0.2853570173003773 0.058929662482305 0.9530081318549856 1.0 1.0 6 P61088,P54132,P49959 3 +Negative regulation of fatty acid biosynthetic process 0.2672374963257317 0.0587305765961665 0.9531667047629132 1.0 1.0 7 Q8WXW3,Q96EB6 2 +Negative regulation of organ growth 0.3110638623438424 0.0586575865320455 0.9532248421802958 1.0 1.0 5 P25490 1 +Sulfur amino acid biosynthetic process 0.2848492102130979 0.0582169858614089 0.9535757909078848 1.0 1.0 6 P11586,Q9BV20,P32929 3 +Mitochondrial genome maintenance 0.24515116144287 0.0577435595232706 0.9539528960777436 1.0 1.0 9 P49916,P09874 2 +Positive regulation of nucleocytoplasmic transport 0.2019988909238965 0.0576227690991455 0.9540491126859164 1.0 1.0 31 O95071,P12270,Q13263,Q9NPF5,Q9NW64,Q9H7Z3,Q07666,P08238,Q7Z434,P21333,Q05655,P50402 12 +Negative regulation of response to endoplasmic reticulum stress 0.2156978579623195 0.0570521792224583 0.9545036297865026 1.0 1.0 15 Q9Y4L1 1 +Response to molecule of bacterial origin 0.1989936498081921 0.0568825761554219 0.954638734051308 1.0 1.0 38 Q96JM3,P26583,P78536,Q02952 4 +Regulation of protein binding 0.1993564884886546 0.0561774825322483 0.955200419165266 1.0 1.0 57 Q13464,P30533,Q13526,P10586,P62913,Q08379,Q9H2P0,P48681 8 +Epigenetic maintenance of chromatin in transcription competent conformation 0.3085943616603311 0.0556370334087037 0.9556309617889228 1.0 1.0 5 O75367,Q96GM5 2 +Regulation of trans synaptic signaling 0.1998349909974282 0.0551311014577591 0.9560340184358668 1.0 1.0 62 P33176,Q12834,O95793,P55011,P51608,P19022,Q9H2P0,Q14168,Q15042,P40818,Q9UNF0,Q02952 12 +Negative regulation of muscle hypertrophy 0.2637456130029743 0.0538131580396297 0.9570840261110029 1.0 1.0 7 P02545 1 +Positive regulation by host of viral genome replication 0.3068172313218378 0.0535245555744362 0.9573139661693342 1.0 1.0 5 Q9H1E3 1 +Export across plasma membrane 0.2374657295077646 0.0534826709766562 0.9573473374441192 1.0 1.0 10 P0DP25,P20020,P05026 3 +Membrane hyperpolarization 0.4073869900771653 0.0532143707246301 0.9575611056566056 1.0 1.0 2 P04179 1 +Positive regulation of inflammatory response to antigenic stimulus 0.4073869900771638 0.053214370724629 0.9575611056566063 1.0 1.0 2 Q15046 1 +Intrinsic apoptotic signaling pathway in response to hydrogen peroxide 0.407386990077163 0.0532143707246281 0.9575611056566072 1.0 1.0 2 Q12931 1 +Regulation of proteasomal protein catabolic process 0.1936260789391263 0.052877636854905 0.957829402667826 1.0 1.0 76 P0DMV9,P82094,Q12834,Q04323,Q9NZM5,P17980,O75150,P62913,P61956,Q9UMX0,P55072,Q6ZXV5 12 +Interleukin 10 production 0.305422746779207 0.0519024604278557 0.958606413782364 1.0 1.0 5 Q8WXW3,P10809 2 +Regulation of coagulation 0.3044741460061841 0.0508167545946814 0.9594715398901752 1.0 1.0 5 Q4KMQ2,P80404 2 +Ribonucleoside diphosphate metabolic process 0.1964758961551717 0.0503076258036399 0.959877246953864 1.0 1.0 47 Q96DE0,P54819,Q9UDY2,P18669,Q9BW91,P27144,P09104,Q05682,Q14168,Q9UIJ7 10 +L proline biosynthetic process 0.3038674607395719 0.0501298684903629 0.960018898040314 1.0 1.0 5 Q96C36,P54886 2 +Regulation of cellular amino acid metabolic process 0.4074993107251119 0.0498173056622192 0.9602679758814514 1.0 1.0 3 P23634,O14874 2 +Circulatory system development 0.2613839516983102 0.0497387169509376 0.960330602962467 1.0 1.0 175 Q13464,P04083,P55011,P51608,Q96AY3,O95747,Q05682,O75179,Q15648,Q96HC4,Q9UII2,Q9P2D1,Q12802,Q07157,O75147,Q4VCS5,Q04721,Q9BQ70,Q96JM3,O75592,Q13043,P19022,P80723,Q96PU8,Q5JRA6,O95487,P25490,P13807,Q96T37,P19338,Q13308,P26358,Q96EB6,Q9UGM6,P02545,O14964,P35579,Q15149,Q12904,Q9NR12,P42345,O96013,P43243,Q9Y366,Q8NCM8,O94788,O75116,P21333,O94992 49 +Aspartate family amino acid catabolic process 0.2601843810034959 0.049066858786665 0.9608660144377954 1.0 1.0 7 P36957,P52758,P00505 3 +Hepatocyte differentiation 0.3267229130779261 0.0490092173042944 0.9609119504216164 1.0 1.0 4 P17301,P04083 2 +Peptidyl cysteine modification 0.2592859130239073 0.0479116100677002 0.9617866865221568 1.0 1.0 7 P08397 1 +Dedifferentiation 0.3996692392502676 0.0469164015098269 0.9625798559739628 1.0 1.0 2 Q14103 1 +Positive regulation of nervous system development 0.1958049729514711 0.0462386721250209 0.963120019524788 1.0 1.0 46 O75147,P42345,Q13573,Q9UQB8,Q14444,P53990,Q13049,Q9H2P0 8 +Positive regulation of leukocyte apoptotic process 0.3002461298616196 0.0461501146136755 0.9631906028459698 1.0 1.0 5 P04083,Q96EB6 2 +Establishment of protein localization to plasma membrane 0.1975032617289985 0.0461385411931926 0.963199827273477 1.0 1.0 27 O15027,Q9H8Y8,Q8IWJ2,Q01082 4 +Protein localization to postsynapse 0.3223938223938234 0.0448646465876917 0.9642151963908758 1.0 1.0 4 Q14160,Q15334,P61006 3 +Regulation of hemopoiesis 0.195221441010678 0.0441673139020655 0.9647710363439156 1.0 1.0 46 P0DMV9,P04083,Q8IYB5,Q96T37,Q9UKV3,P26583,P42345,Q04721,O15347,Q15648,O95628,O43290,P62805 13 +Positive regulation of lamellipodium organization 0.2093707164520269 0.0437473533917846 0.9651057927763912 1.0 1.0 17 P42345,Q16625,Q9ULV4,Q9Y6W5 4 +Negative regulation of cell adhesion mediated by integrin 0.3992280121312338 0.0433519063511265 0.9654210148005612 1.0 1.0 3 Q9BX67,Q9H4A3 2 +Negative regulation of cartilage development 0.3992280121312337 0.0433519063511262 0.9654210148005616 1.0 1.0 3 P35222,Q8N5W9 2 +Negative regulation of chondrocyte differentiation 0.3992280121312337 0.0433519063511262 0.9654210148005616 1.0 1.0 3 P35222,Q8N5W9 2 +Histone h3 k4 demethylation 0.3989523021781033 0.0431480152616628 0.9655835442710492 1.0 1.0 3 Q8IUF8,O60341 2 +Membrane depolarization during action potential 0.3938809261300896 0.0426213740784739 0.9660033569197076 1.0 1.0 2 Q12955 1 +Phosphatidylinositol 3 phosphate biosynthetic process 0.2957979705120483 0.0415389305988645 0.9668662574936904 1.0 1.0 5 O00443,Q96PE3 2 +Myeloid cell activation involved in immune response 0.2244824835519638 0.0406658571065085 0.9675622811496734 1.0 1.0 12 Q12846,P11274,P51809,O95219,Q15046 5 +Negative regulation of phagocytosis 0.2531028159371168 0.0404119211513639 0.9677647263094662 1.0 1.0 7 O60493 1 +Tryptophan transport 0.390573318632841 0.040325093374426 0.9678339484263794 1.0 1.0 2 Q01650 1 +Leucine import across plasma membrane 0.390573318632841 0.040325093374426 0.9678339484263794 1.0 1.0 2 Q01650 1 +Leucine transport 0.390573318632841 0.040325093374426 0.9678339484263794 1.0 1.0 2 Q01650 1 +Regulation of gastrulation 0.315598273757576 0.0388489788680253 0.9690107947952388 1.0 1.0 4 O95747 1 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.2350479928849443 0.0381839848889397 0.9695409897912464 1.0 1.0 8 Q96SN8,O94992,Q01664 3 +Viral genome replication 0.1920311232037208 0.0381285448726781 0.9695851923352978 1.0 1.0 49 P11940,Q16513,O95793,Q6PKG0,Q15075,Q12906,Q9H1E3,O75116,P55072,Q7Z434 10 +Organism emergence from protective structure 0.2913103448275903 0.0371884116265988 0.9703347784045092 1.0 1.0 5 Q9BZK7,Q8IWS0,O43678,Q12824 4 +Positive regulation of blood vessel endothelial cell migration 0.2216355894940578 0.0366570587625709 0.970758447755875 1.0 1.0 12 P04083,P78536 2 +Protein folding in endoplasmic reticulum 0.2256859114931682 0.0365616142849646 0.9708345504158024 1.0 1.0 10 Q86YB8,P14625,Q13217,P30101 4 +Glucose 6 phosphate metabolic process 0.2236399891798109 0.0363042134400466 0.9710397903167916 1.0 1.0 11 P29401 1 +Positive regulation of organelle organization 0.255575794465816 0.0351476050233212 0.9719620415228556 1.0 1.0 169 Q96ST3,Q9Y281,P46821,Q13283,P04083,Q96HS1,Q9NWH9,Q96GD0,O60832,P51608,Q9UHD8,Q9UHV9,Q8NEY8,O60504,Q15398,O95219,P26038,P39748,P49593,Q9UII2,Q96QC0,P12270,O60934,O75146,Q15555,O14737,Q92878,P48681,Q14247,O00165,Q14008,P0DMV9,P23246,Q14203,Q9P270,P49257,Q14980,P26358,Q9Y6W5,Q15042,Q9GZY8,Q96T60,P60903,Q04837,P42345,Q16625,P14373,O75116,P22059,Q9UN86,Q9UQB8,O95347 52 +Positive regulation of homotypic cell cell adhesion 0.3820286659316343 0.0348998493457039 0.9721596007460636 1.0 1.0 2 Q12955 1 +Positive regulation of axonogenesis 0.2030463641223706 0.0335720026373602 0.9732184483372476 1.0 1.0 17 P46821,Q9H2P0,P53990 3 +Negative regulation of jnk cascade 0.2870796068143093 0.0333560131939316 0.9733906865125328 1.0 1.0 5 P31689 1 +Positive regulation of posttranscriptional gene silencing 0.2128836051976758 0.0324673378635906 0.974099362899446 1.0 1.0 13 P26196,O60573,P51114,P40763,Q13546,Q06787,Q9HAV4,Q04637,Q02750,Q01085,P04637,P17844 12 +Negative regulation of histone h4 acetylation 0.3827360861162135 0.0324033266980881 0.9741504095612068 1.0 1.0 3 Q96EB6 1 +T cell extravasation 0.3821339950372162 0.0320496728680229 0.9744324380026488 1.0 1.0 3 P46109,P46108 2 +Protein k6 linked ubiquitination 0.3767916207276625 0.0319181416063526 0.9745373311005364 1.0 1.0 2 Q16763 1 +Myoblast differentiation 0.2216879904191558 0.0316518902821818 0.9747496616362488 1.0 1.0 10 Q9H7N4 1 +Positive regulation of small gtpase mediated signal transduction 0.2255443168798276 0.0315167533563825 0.9748574315354724 1.0 1.0 9 Q12802,Q04721 2 +Negative regulation of tor signaling 0.2618337176393398 0.0309694524812357 0.9752939013704542 1.0 1.0 6 Q14249 1 +Negative regulation of steroid metabolic process 0.3785497656465343 0.0300079519786728 0.9760607112660205 1.0 1.0 3 O75477,O94905 2 +Positive regulation of blood pressure 0.3782740556934064 0.0298553492317476 0.9761824161114864 1.0 1.0 3 P11766,Q9H4A3 2 +Regulation of cellular protein catabolic process 0.2008110304025739 0.0297210697981813 0.976289508074387 1.0 1.0 96 Q9UII2,P0DMV9,P82094,Q12834,Q04323,Q9NZM5,P17980,O75150,P62913,P15311,P61956,O60826,P62081,P55072,Q9UMX0,P46777,Q6ZXV5 17 +Positive regulation of cell population proliferation 0.233244139268408 0.0294650848807238 0.976493665072424 1.0 1.0 136 Q9NQG5,Q9UPN4,P04083,Q12834,P51608,P46087,O95747,Q15648,P07942,Q8IX12,Q07157,P49006,Q04721,Q96JM3,Q96QE3,P48681,Q01085,P62753,P06748,Q15910,P84095,P26358,Q86VI3,P11047,Q96EY1,P26583,O00311,Q14978,P78536,O94788 30 +Translational termination 0.2426166160640328 0.029414435868371 0.9765340596286318 1.0 1.0 7 P61221,P62495,P13798,Q92900,P15170,Q14197 6 +Positive regulation of histone h4 acetylation 0.3768955059277584 0.0291017354326594 0.9767834517103322 1.0 1.0 3 Q12824,O95251 2 +Positive regulation of sphingolipid biosynthetic process 0.3712789415655871 0.029044750605644 0.9768288998123597 1.0 1.0 2 Q05655 1 +Regulation of sphingolipid biosynthetic process 0.3712789415655871 0.029044750605644 0.9768288998123597 1.0 1.0 2 Q05655 1 +Regulation of cellular component size 0.1961215969011303 0.0289935109348451 0.976869765944075 1.0 1.0 91 Q96ST3,Q9Y281,P59998,Q96GD0,P42345,P55011,Q5SSJ5,O75146,P15311,Q86VI3,Q9UHB6,Q9H2P0,P53990,Q13813,Q01082,P47755,Q14247,O14745 18 +Negative regulation of dna damage response signal transduction by p53 class mediator 0.2814250076900019 0.0286270553588211 0.9771620338676714 1.0 1.0 5 Q96EB6 1 +Developmental growth 0.2248611030824817 0.0285863199653817 0.97719452271295 1.0 1.0 125 Q96ST3,P46821,P04083,Q9BRX2,O60271,Q9NZM3,P46940,Q15648,Q92541,Q96HC4,P11802,P18206,Q7Z6E9,Q9P2D1,Q12802,O60934,Q04721,P15311,Q13043,P80723,Q7Z4V5,Q14247,P25490,Q15910,Q13308,P11047,Q15056,P58107,Q9H2P0,Q15149,P42345,Q9BRT6,P53990 33 +Positive regulation of viral life cycle 0.2250267408300295 0.0276156273663671 0.9779687175830648 1.0 1.0 8 P19474,Q9UN37 2 +Regulation of cell communication by electrical coupling 0.3733860083076418 0.0272528463094687 0.9782580660779964 1.0 1.0 3 P0DP25 1 +Positive regulation of tyrosine phosphorylation of stat protein 0.3732595820633199 0.027188080710411 0.9783097224085284 1.0 1.0 3 P22059 1 +Negative regulation of stress activated protein kinase signaling cascade 0.220856872625297 0.0266056954553511 0.9787742305525384 1.0 1.0 9 P15311,P31689 2 +Trna threonylcarbamoyladenosine metabolic process 0.2571743929359788 0.0265865868907828 0.9787894715898232 1.0 1.0 6 Q9Y3C4,Q7L0Y3,Q9Y606,Q96SZ6,Q9H3H1 5 +Positive regulation of histone h3 k9 acetylation 0.3713813068651732 0.0262406914696585 0.9790653599468868 1.0 1.0 3 Q12824,P38398 2 +Regulation of organelle organization 0.2704950407672492 0.0249545519404997 0.9800912146048996 1.0 1.0 366 Q96ST3,P46013,Q9NWH9,Q12834,Q8TD16,Q96GD0,Q92974,Q12802,Q07157,Q9H981,O14737,Q92878,P48681,P25490,P06748,P0DMV9,P23246,Q9Y6D9,Q9P270,P27816,Q14980,Q9UHB6,Q01082,Q15042,Q9GZY8,Q16625,P14373,P22059,Q9UQB8,Q9Y281,Q13464,P04083,Q9UQN3,O60832,P51608,P18887,Q9HD42,Q9UIG0,Q9UII2,O75147,P12270,O60934,Q9Y5K6,Q04721,P19022,Q9NYB0,Q9NZZ3,Q9H444,P84095,P49257,P26358,P49750,Q99640,Q9NYL9,Q9ULW0,Q9Y6G9,O60610,P47755,O75116,P46821,Q13283,Q96HS1,Q9Y3E7,Q9Y3E1,Q9UHD8,Q9UHV9,P35611,P46940,O15344,P16949,O75592,Q13813,Q5VU43,Q4KMP7,Q96PK6,P21333,O95347,Q5T2E6,Q8WWK9,Q13123,Q7Z6Z7,Q15398,Q13136,P39748,Q96QC0,Q13526,O75146,P15311,Q7Z7K6,Q14008,Q14247,P59998,Q14203,Q86VI3,P02545,Q7Z434,Q9Y6A5,Q96T60,P09874,P42345 100 +Embryonic cranial skeleton morphogenesis 0.2964784564496724 0.0249154215089372 0.980122426467547 1.0 1.0 4 Q6UB35 1 +Intestinal epithelial cell differentiation 0.3597023153252389 0.0238307143670739 0.9809876404798064 1.0 1.0 2 P04818 1 +Intestinal epithelial cell development 0.3597023153252389 0.0238307143670739 0.9809876404798064 1.0 1.0 2 P04818 1 +Carbohydrate mediated signaling 0.2944785820511699 0.0236944114278845 0.9810963637903404 1.0 1.0 4 P17480 1 +Zinc ion import across plasma membrane 0.3583241455347217 0.0232791111028536 0.9814276341238092 1.0 1.0 2 Q9ULF5 1 +Natural killer cell differentiation 0.3647642679900693 0.0231183878191068 0.981555838247118 1.0 1.0 3 Q9ULT8,O95251 2 +Gamma aminobutyric acid metabolic process 0.3642128480838109 0.0228729004748832 0.9817516570271588 1.0 1.0 3 P80404,O43175 2 +Anterograde axonal transport 0.19862859260893 0.0225553721289827 0.982004942643402 1.0 1.0 14 Q14168,Q9Y496,P33176 3 +Positive regulation of interleukin 2 production 0.2346855141183066 0.0224366260073097 0.9820996643695412 1.0 1.0 7 P04083,Q01082 2 +Attachment of gpi anchor to protein 0.2923331494760151 0.0224308715074731 0.9821042546408908 1.0 1.0 4 Q92643,O43292,Q969N2 3 +Regulation of mitochondrial membrane potential 0.1956752377074948 0.0218632539477765 0.9825570368654016 1.0 1.0 21 Q9UII2,O75915,P09874 3 +Histone serine phosphorylation 0.2716919935383642 0.0214845576527143 0.9828591218288836 1.0 1.0 5 Q13043,Q99986 2 +Positive regulation of hexokinase activity 0.3598014888337414 0.0209873573717982 0.9832557408116692 1.0 1.0 3 Q9UNI6,P49792 2 +Regulation of hexokinase activity 0.3598014888337414 0.0209873573717982 0.9832557408116692 1.0 1.0 3 Q9UNI6,P49792 2 +Negative regulation of amyloid precursor protein biosynthetic process 0.3503307607497138 0.0203466463281691 0.9837668450882218 1.0 1.0 2 Q9NY61 1 +Protein localization to nucleus 0.2216392847949607 0.0199309632515949 0.9840984449442832 1.0 1.0 123 Q96ST3,Q9UKX7,O60832,Q9NPF5,P62913,P49790,Q15648,P51858,Q96QC0,P12270,Q9NZM5,Q13526,Q9Y5K6,Q15050,Q13043,P55735,Q5JTV8,P35658,Q7L2J0,Q76FK4,P02545,Q7Z434,Q8NFH5,P09874,O75190,Q14978,P21333 27 +Threonine metabolic process 0.3564929693961902 0.0196620400362986 0.984312972584195 1.0 1.0 3 O43175,P52758 2 +Tyrosine metabolic process 0.3548387096774146 0.0190269994577412 0.9848195668534973 1.0 1.0 3 P61457,O43708 2 +Regulation of actin nucleation 0.2091236376739955 0.0187283258940225 0.9850578314193276 1.0 1.0 10 P14373,O75146 2 +Regulation of deoxyribonuclease activity 0.2144508618847722 0.0186513370175214 0.9851192489274204 1.0 1.0 8 P06748,Q05655,Q96EB6 3 +Medium chain fatty acyl coa metabolic process 0.3442668136714346 0.018406511533205 0.985314557871248 1.0 1.0 2 P51659 1 +Regulation of xenophagy 0.3428886438809178 0.0179975286407982 0.9856408249516312 1.0 1.0 2 P27361 1 +Pyrimidine nucleobase catabolic process 0.3512645535484297 0.017715870382938 0.9858655199000936 1.0 1.0 3 Q9BPU6 1 +Nucleobase catabolic process 0.3512645535484297 0.017715870382938 0.9858655199000936 1.0 1.0 3 Q9BPU6 1 +Hydrogen sulfide metabolic process 0.3490488006616985 0.016943720848698 0.9864815135716802 1.0 1.0 3 P25325,P32929 2 +Myd88 dependent toll like receptor signaling pathway 0.3373759647188423 0.0164730312024638 0.9868570171515808 1.0 1.0 2 P10809 1 +Outflow tract septum morphogenesis 0.3362734288864303 0.0161887201556593 0.9870838342977284 1.0 1.0 2 Q9NVD7 1 +Limbic system development 0.1893489874103402 0.0148778786014549 0.9881296082890654 1.0 1.0 24 P18887 1 +Cellular response to leucine starvation 0.2772415871673598 0.0148116824409363 0.9881824193642748 1.0 1.0 4 P42345 1 +Regulation of p38mapk cascade 0.3381189461859335 0.0135614583655914 0.9891798534103527 1.0 1.0 3 P15311 1 +Neuron projection extension involved in neuron projection guidance 0.3365463224277156 0.0131297448087225 0.9895242803159364 1.0 1.0 3 Q13740 1 +Salivary gland development 0.3363661428177505 0.0130811176486508 0.9895630758444354 1.0 1.0 3 P60953,P26367 2 +Riboflavin metabolic process 0.3213891951488329 0.0129536739134088 0.9896647526180258 1.0 1.0 2 Q969G6 1 +Trna 3 end processing 0.2571034482758658 0.0129246652602896 0.9896878962370206 1.0 1.0 5 P05455,Q7L0Y3,Q9BQ52,O75127 4 +Smooth muscle cell migration 0.1992813709231648 0.0127085273421935 0.9898603351811026 1.0 1.0 12 P31949,O94813,P46108,O14786,Q9BR76,P17301,P09493,Q96N67,Q9NVD7,P27695,Q14344 11 +Gamma aminobutyric acid transport 0.3349516453227179 0.0127052545200343 0.9898629463045624 1.0 1.0 3 O14745 1 +Stem cell differentiation 0.1843364030316175 0.0124251627227444 0.9900864095831106 1.0 1.0 42 O95747,P19022,Q14978,Q13428 4 +Central nervous system neuron differentiation 0.1886457206927725 0.0121848036630856 0.9902781738470864 1.0 1.0 22 Q8NCM8,Q8N3R9,O75592 3 +Ncrna 3 end processing 0.1875040030906061 0.0120003970866325 0.990425298249674 1.0 1.0 24 O60832,Q9H0H0,Q8N201 3 +Positive regulation of lamellipodium assembly 0.1928212307788415 0.0118737564515623 0.9905263356582406 1.0 1.0 13 P42345,Q16625,Q9Y6W5 3 +Negative regulation of transmembrane transport 0.1882657933165225 0.0116899380230656 0.990672991364989 1.0 1.0 22 O95747,O75915,O14745 3 +Negative regulation of signal transduction in absence of ligand 0.2181838401207826 0.0111882728948421 0.9910732360338036 1.0 1.0 7 P0DMV9 1 +Regulation of mitotic cytokinesis 0.327819134270742 0.0109628993445484 0.9912530470806922 1.0 1.0 3 Q96Q89,P37198 2 +Positive regulation of membrane potential 0.2360382749424437 0.0108840383297104 0.9913159653129824 1.0 1.0 6 P55072 1 +Peptide transport 0.1832370431441466 0.0107935823319133 0.9913881345176954 1.0 1.0 41 Q8N183 1 +Organelle inheritance 0.2009425771763087 0.0107348138232101 0.9914350222869706 1.0 1.0 9 P27361,Q08379,Q99986,P28482 4 +Regulation of arp2 3 complex mediated actin nucleation 0.2021925149946679 0.0107186762382024 0.991447897476146 1.0 1.0 8 Q9Y6W5,O75146 2 +Mrna 3 end processing by stem loop binding and cleavage 0.3059536934950289 0.0106003596395157 0.9915422951003372 1.0 1.0 2 Q9P2I0 1 +Excitatory synapse assembly 0.303472987872096 0.0103002114265503 0.9917817656480532 1.0 1.0 2 Q9Y639 1 +Positive regulation of vascular associated smooth muscle cell apoptotic process 0.3242914329462676 0.0101903332393539 0.9918694311560898 1.0 1.0 3 Q53EL6 1 +Negative regulation of cell volume 0.3004410143329558 0.0099589717327838 0.9920540215616608 1.0 1.0 2 Q4KMQ2 1 +Axonal transport 0.1865636533281943 0.0099169772913768 0.9920875266235198 1.0 1.0 21 Q14203,Q14168,Q9Y496,P33176 4 +Reelin mediated signaling pathway 0.3176178660049582 0.0088772788309837 0.9929170493088672 1.0 1.0 3 P46109,P46108 2 +Positive regulation of axon extension 0.1939937717446455 0.008760884852089 0.993009914656118 1.0 1.0 12 P46821,Q9H2P0 2 +Ossification 0.1883201786057452 0.0083665682691838 0.9933245222311842 1.0 1.0 62 P35998,P84243,P38159,O95747,Q7KZF4,P61604,Q9P2E9,Q9NR30,P62841,Q86V81,P27361,P67936,Q00839,P07910,Q9NY93,O75165,O60506,P18074,Q9NR12,P51659,Q14696,Q9NUQ3,Q4KMQ2,P20020,P63173,Q9Y3A5,P17844 27 +Regulation of transporter activity 0.1826626619583667 0.0082366336624699 0.993428191475396 1.0 1.0 48 Q09666,P54652,O95747,P05026,P46939,O14745 6 +Regulation of membrane tubulation 0.2778390297684565 0.0081494791750269 0.9934977283613976 1.0 1.0 2 P50570 1 +Positive regulation of phosphorus metabolic process 0.2359552702439845 0.0079238155537543 0.9936777760658364 1.0 1.0 146 Q13464,Q8IZP0,Q9NWH9,Q96N67,P46940,Q99627,Q92974,Q15435,Q13177,Q9UER7,P26599,Q12802,O60934,Q13526,O14974,Q96JM3,Q13043,Q9NYB0,Q92878,Q9NQS7,O00165,Q15910,P30040,Q86VI3,Q96EB6,Q9UJZ1,Q9ULW0,P08238,Q7Z434,Q9H2P0,Q13432,Q9H223,P42345,P54652,Q969S3,O75116,P22059,P55072,P67870,P78536,Q9H7B4 41 +Mitochondrial ribosome assembly 0.2302589539807917 0.0076553255094641 0.9938919936270796 1.0 1.0 6 Q7L2E3 1 +Dendrite self avoidance 0.3021251279750376 0.0064855687744379 0.99482530108376 1.0 1.0 3 Q9Y639 1 +Histone h2a monoubiquitination 0.2490964468567054 0.0055712696697573 0.995554792942274 1.0 1.0 4 Q99496 1 +Positive regulation of arp2 3 complex mediated actin nucleation 0.2933553901295789 0.0054740958733457 0.9956323252317376 1.0 1.0 3 Q9Y6W5,Q7L576 2 +Negative regulation of type i interferon production 0.2391724137931077 0.0054034940874984 0.9956886564734596 1.0 1.0 5 Q8TAT6,O75531,Q92890,P25490 4 +Cellular response to dna damage stimulus 0.2820573819084444 0.0052330345434224 0.995824661588361 1.0 1.0 260 Q9GZR2,Q15014,Q14249,Q14683,O60885,Q9NPF5,Q13573,P54098,Q7Z6Z7,P20585,P18887,Q14676,Q9UNS1,Q13049,Q9UIG0,P39748,Q15233,Q7Z6E9,Q7Z3K3,Q96QC0,Q9HAF1,P25205,O60934,Q9NZM5,Q7Z4V5,Q9H981,Q9NXV6,P61088,Q9NYB0,Q92878,Q96QE3,P25490,P06748,Q9Y2K7,P16104,P23246,Q01664,Q9UQE7,P61254,Q9UM54,Q99459,Q96EB6,Q13185,Q13111,Q14807,P33991,P54132,Q13769,Q9NYF8,Q9C0J8,Q96T60,P26583,P09874,Q9BW85,O00311,Q15291,P49916,Q13112,Q9H7Z3,Q9H1E3,Q92499,P55072,P22314,Q9NRF9,Q15906 65 +Regulation of nadp metabolic process 0.2353103448275901 0.0041503001173569 0.996688549120284 1.0 1.0 5 P48163,Q9NQ88,P04637,P18669 4 +Regulation of phagocytosis 0.1775551305943192 0.0040618418869019 0.996759127981641 1.0 1.0 19 O60493,P11274,Q92614,P17301,Q9NT62,Q9NX58,Q4KMQ2,P50570,P09429 9 +Positive regulation of wnt signaling pathway 0.1808707403989592 0.0029168857823012 0.997672665168924 1.0 1.0 24 Q13308,Q13526,P40818 3 +Vesicle mediated transport to the plasma membrane 0.1855074898516059 0.0021721633188094 0.9982668657872856 1.0 1.0 59 O60493,O43752,Q567U6,O15027,Q9H4M9,O60826,Q96KP1,Q07960,Q8IWJ2 9 +Regulation of cell size 0.180180699164917 0.0019463067793996 0.9984470728505744 1.0 1.0 45 Q96ST3,P46821,P35241,P42345,P55011,Q86VI3,P15311,Q9UJU6,Q4KMQ2,Q8N0X7,P50570,P53990,P08238,Q9H2P0,P26038,Q14247,O14745 17 +Nadh metabolic process 0.1726224672664186 0.0017748314675794 0.9985838901174552 1.0 1.0 18 P55072,P09104 2 +Arginine catabolic process 0.2173193601765073 0.0005267340435943 0.9995797270584008 1.0 1.0 4 P23634,P78540,P16930 3 +Negative regulation of protein polymerization 0.1769903418351004 0.0004340822624218 0.999653652475572 1.0 1.0 30 P16949,O75146,Q9NYL9,Q13813,Q01082,P47755 6 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bd39ec6d63e887cb4234dee5991bb6e09a9341ea --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Acrosome reaction", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of janus kinase activity", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult heart development", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular node development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone mineralization involved in bone maturation", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac myofibril assembly", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac right ventricle morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system myelin maintenance", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide 1 phosphate transport", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chiasma assembly", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen activated signaling pathway", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common bile duct development", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Convergent extension involved in gastrulation", "Convergent extension involved in organogenesis", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Copulation", "Cornea development in camera type eye", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo nad biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of mechanical stimulus involved in sensory perception", "Detection of mechanical stimulus involved in sensory perception of pain", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of stimulus involved in sensory perception of pain", "Detection of temperature stimulus", "Detection of temperature stimulus involved in sensory perception", "Detection of temperature stimulus involved in sensory perception of pain", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna cytosine deamination", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic camera type eye morphogenesis", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic eye morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat pad development", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain dorsal ventral pattern formation", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain neuron fate commitment", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "Galactolipid biosynthetic process", "Galactolipid metabolic process", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastric acid secretion", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glomerulus morphogenesis", "Glomerulus vasculature morphogenesis", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Heat generation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell migration", "Hematopoietic stem cell migration to bone marrow", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune complex clearance", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 mediated signaling pathway", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 4 production", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iris morphogenesis", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lacrimal gland development", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte migration involved in inflammatory response", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of animal organ identity", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Marginal zone b cell differentiation", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Melanosome assembly", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Menaquinone metabolic process", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motile cilium assembly", "Motor behavior", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multinuclear osteoclast differentiation", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myoblast proliferation", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell cytokine production", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of catecholamine secretion", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular extravasation", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of dopamine secretion", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 beta production", "Negative regulation of interleukin 1 production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage derived foam cell differentiation", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil activation", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of non canonical wnt signaling pathway", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of sterol transport", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell cytokine production", "Negative regulation of t cell differentiation", "Negative regulation of t cell mediated immunity", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Negative t cell selection", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal signal transduction", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Olfactory nerve development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Osteoclast fusion", "Otic vesicle development", "Otic vesicle formation", "Otic vesicle morphogenesis", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic a cell differentiation", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid efflux", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alkaline phosphatase activity", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagosome maturation", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell differentiation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol esterification", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of corticosteroid hormone secretion", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermal growth factor activated receptor activity", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial cell proliferation involved in wound healing", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of hair follicle maturation", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of heat generation", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 13 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 4 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of mucus secretion", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myoblast proliferation", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein kinase c signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein localization to synapse", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid hormone secretion", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 2 signaling pathway", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of uterine smooth muscle contraction", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to non motile cilium", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to photoreceptor outer segment", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein palmitoylation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside catabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Receptor transactivation", "Recognition of apoptotic cell", "Recombinational repair", "Reduction of food intake in response to dietary excess", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of acrosome reaction", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adiponectin secretion", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alkaline phosphatase activity", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of asymmetric cell division", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of blood vessel remodeling", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone mineralization involved in bone maturation", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell differentiation", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte development", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of growth rate", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of heat generation", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of ketone biosynthetic process", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myoblast proliferation", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil activation", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil degranulation", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non canonical wnt signaling pathway", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast development", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of positive chemotaxis", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle cell proliferation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type b pancreatic cell proliferation", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to fluoride", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoprotein", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 18", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Semicircular canal development", "Semicircular canal morphogenesis", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of bitter taste", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of smell", "Sensory perception of sweet taste", "Sensory perception of taste", "Sensory perception of temperature stimulus", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm flagellum assembly", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Strand invasion", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymic t cell selection", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Thyroid hormone transport", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Triglyceride rich lipoprotein particle clearance", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent glycoprotein erad pathway", "Ubiquitin dependent protein catabolic process via the c end degron rule pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Ureter morphogenesis", "Ureteric bud elongation", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "ALYREF", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APOBEC3C", "APOC1", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf76", "C12orf43", "C12orf57", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C2CD2L", "C2CD5", "C2orf49", "C3orf58", "C5orf51", "C9orf64", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC93", "CCDC94", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPH", "CENPK", "CENPP", "CENPU", "CENPV", "CEP131", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD6", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM129B", "FAM162A", "FAM173A", "FAM207A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNBP1", "FNDC3A", "FNTA", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC1", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHITM", "GID4", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRS4", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS24", "MRPS27", "MRPS28", "MRPS30", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTF2", "MTFP1", "MTFR1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKBIL1", "NFS1", "NFU1", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAWR", "PAX6", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD11", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCOC", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLAIN2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TCTN3", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM161A", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1AIP2", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBL5", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMA21", "VMP1", "VPS13A", "VPS13D", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WRAP73", "WRN", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFPL1", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AAK1", "AARSD1", "AASDHPPT", "AATF", "ABAT", "ABCB6", "ABCD4", "ABCE1", "ABCF1", "ABCF3", "ABI1", "ABR", "ACADM", "ACADS", "ACADVL", "ACIN1", "ACO2", "ACSF3", "ACTN1", "ACTN4", "ACTR8", "ADAM17", "ADAR", "ADD1", "ADH5", "ADNP", "AFDN", "AFG3L2", "AGL", "AHCTF1", "AHNAK", "AIMP1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKR1A1", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH4A1", "ALDH5A1", "ALKBH5", "ALYREF", "AMOT", "ANK3", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANXA1", "AP3S1", "APEH", "APEX1", "ARCN1", "ARFGAP1", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARL3", "ARL6IP4", "ARL6IP5", "ARPC2", "ARPC4", "ARVCF", "ATAD5", "ATF7", "ATG3", "ATP1B1", "ATP2B1", "ATP2B4", "ATP6V1D", "ATPIF1", "ATRX", "ATXN2L", "B4GALT3", "BAG2", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCKDK", "BCLAF1", "BCR", "BICD2", "BIRC6", "BLM", "BMS1", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BTF3", "BUD23", "BUD31", "C10orf76", "C1QBP", "C2orf49", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALR", "CAPRIN1", "CAPZA2", "CAST", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCDC124", "CCDC22", "CCDC93", "CCDC94", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CDC20", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDK4", "CDK5RAP1", "CDK5RAP2", "CDKN2A", "CDKN2AIP", "CELF2", "CENPH", "CENPV", "CEP131", "CEP250", "CEP290", "CFDP1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD4", "CHD7", "CHD8", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHTF18", "CHTOP", "CIZ1", "CKAP2", "CKAP5", "CKMT1A*", "CLASP1", "CLPB", "CLPX", "CLTA", "CLU", "CLUH", "CNOT11", "CNOT3", "CNOT4", "COG6", "COPB2", "COPS7A", "COPS7B", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CPSF2", "CPSF6", "CPSF7", "CRK", "CRKL", "CRYZ", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CTBP1", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTTN", "CTU2", "CUL4B", "CWC15", "CWC27", "CYB5D2", "CYFIP1", "DAXX", "DBNL", "DCAF1", "DCAF13", "DCP1B", "DCTN1", "DCTN2", "DDI2", "DDX1", "DDX10", "DDX20", "DDX21", "DDX23", "DDX27", "DDX3X", "DDX41", "DDX46", "DDX5", "DDX54", "DDX56", "DDX6", "DENND4C", "DHFR", "DHRS13", "DHRS7B", "DHX30", "DHX37", "DIAPH1", "DKC1", "DLGAP5", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC9", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DPF2", "DPYSL2", "DPYSL5", "DSG2", "DUSP12", "DUT", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "EBNA1BP2", "EDC4", "EDF1", "EEA1", "EHD1", "EHD4", "EIF2AK2", "EIF2D", "EIF2S2", "EIF4B", "EIF4E2", "EIF4G1", "EIF4G3", "EIF4H", "EIF5B", "ELAC2", "ELMO2", "ELOA", "ELP3", "EMD", "EML4", "ENAH", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41L2", "EPB41L3", "EPPK1", "EPRS", "ERC1", "ERCC2", "ERCC3", "ERLIN1", "ERLIN2", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC7", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZH2", "EZR", "FAH", "FAM207A", "FBL", "FEN1", "FERMT2", "FIP1L1", "FKBP10", "FKBP1A", "FKBP3", "FKBP5", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FRG1", "FTSJ3", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GADD45GIP1", "GAPDH", "GATAD2A", "GATAD2B", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GFM1", "GGA1", "GINS3", "GIPC1", "GLDC", "GNA13", "GNL3", "GNL3L", "GOLGA2", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPKOW", "GRB2", "GRSF1", "GSPT1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C2", "GTF3C5", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HAUS1", "HAUS6", "HAX1", "HCFC1", "HDGF", "HDGFL2", "HDGFL3", "HECTD1", "HELLS", "HEXIM1", "HGS", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HLA-B", "HLA-F", "HMBS", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGN1", "HMGN2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPM", "HNRNPU", "HOOK2", "HOOK3", "HP1BP3", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HUWE1", "HYOU1", "IDH1", "IDH2", "IDH3B", "IFT52", "IGF2BP1", "IGF2BP2", "IK", "ILF3", "ILK", "INA", "INCENP", "INPP4A", "INTS1", "INTS2", "IQCB1", "IQGAP1", "IQGAP3", "IRF2BPL", "IST1", "ISY1", "ITGA2", "ITGAV", "ITPK1", "ITSN2", "JAM3", "KARS", "KAT7", "KDELC2", "KDM1A", "KDM2A", "KDM3B", "KHDRBS1", "KHSRP", "KIDINS220", "KIF18B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KLC1", "KNSTRN", "KRI1", "KTN1", "LAMB1", "LAMC1", "LANCL2", "LARP1", "LARP7", "LARS2", "LEMD2", "LEMD3", "LIG3", "LIMA1", "LLGL1", "LLPH", "LMAN1", "LMNA", "LONP1", "LPGAT1", "LRPAP1", "LRRC47", "LRWD1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LZTFL1", "MAD1L1", "MAD2L1", "MAEA", "MAN1A1", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP7D1", "MAPK1", "MAPK3", "MAPRE2", "MARCKS", "MARCKSL1", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MCM2", "MCM3", "MCM4", "MDC1", "MDH1", "ME1", "MEAF6", "MECP2", "MED1", "MED17", "MED21", "MED25", "MEPCE", "MESD", "METTL13", "MFAP1", "MFF", "MGAT1", "MGST2", "MIA3", "MID1", "MKI67", "MOGS", "MORF4L2", "MPHOSPH10", "MPHOSPH6", "MPP2", "MPP5", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL2", "MRPL24", "MRPL41", "MRPL58", "MRPL9", "MRPS11", "MRPS33", "MRPS35", "MRPS7", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MTR", "MUT", "MYCBP2", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAE1", "NAF1", "NAP1L4", "NBAS", "NBN", "NCBP3", "NCEH1", 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sha256:5982958292e8ae9279c72e7be4631ce8394961a482066f18cd19310dfd69175e +size 206693 diff --git a/msigdb_gocc/df_merge.tsv b/msigdb_gocc/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2aa0df359105353d512bd81b2c0a50e664377dbb --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,91 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Nuclear protein containing complex 166 530 6.619062168369097 3.614848160326729e-11 154.30582524271844 484.0533980582524 -1.0940061612323533 0.422521800070478 47.90867794436856 44.07811978513836 1.3452358698916218 0.3431058895700121 1.0 0.4514148737838713 0.0664012136222828 3.163750054847246e-07 8.749101670933964e-09 +Chromosome 163 479 6.112599035141716 9.802143819233684e-10 145.00485436893203 444.6844660194174 -1.2078687979623326 0.4056739999066477 42.288537037649064 42.242336599836584 1.4711549947790363 0.3366296408420104 1.0 0.605759945475699 0.2624735573027097 0.0041339859954841 9.907859141554562e-06 +Ribonucleoprotein complex 174 458 5.689146967241281 1.2767555087644998e-08 155.03883495145632 425.2330097087379 -1.1500253399218705 0.4211902570470949 45.877352817651584 21.325928374604015 1.55428640606519 0.3469554556195316 1.0 0.1978550340195506 0.0001299369274746 1.3109110922824044e-12 3.081379803131551e-17 +Nucleolus 152 449 4.620301566075602 3.83182675434135e-06 147.54368932038835 417.7839805825243 -1.261856474729523 0.396766896064208 43.590331763845505 29.480690334548896 1.6078064297712815 0.330206758356953 1.0 0.0022191811781427 1.7841784264630544e-05 1.0586903880502828e-11 3.0450491018313408e-15 +Cytosolic ribosome 31 79 4.299922698003284 1.7085769627556147e-05 39.64320388349515 77.44174757281553 -1.1028816270052657 0.3250092147697844 13.34244185985737 1.652889454237942 2.1520560160639124 0.378169291857921 1.0 0.0732573258319426 2.9164279923466545e-05 7.371452599838515e-05 1.015215201498541e-08 +Large ribosomal subunit 35 84 4.106377773243619 4.0191197573147264e-05 31.475728155339805 75.75242718446601 -0.701093514105986 0.409479351501158 11.239532053447306 4.0694062127427815 1.520999775598302 0.3546603200435178 1.0 0.0017602267192959 8.824551097287168e-06 1.0351702134376165e-05 1.5258131008985865e-07 +Catalytic step 2 spliceosome 30 73 3.7715854662618384 0.0001622135782675 24.98058252427185 67.55825242718447 -0.7182873294991192 0.4953678252947486 9.895061612787446 3.6369202876883295 1.2559494583714867 0.3543222715519257 1.0 1.0 0.2027827245191691 0.001103107189202 0.0002208074876855 +Polysome 15 47 3.745589452574381 0.0001799707038645 18.1504854368932 46.30825242718446 -0.3464905176104448 0.5270213705911827 7.423504704278708 2.0168296408864546 1.1797990698219971 0.3537616634296595 1.0 0.0035835009476038 0.0003676689336816 0.0043238685287733 1.4683687741442798e-06 +Contractile fiber 27 61 3.703624623142065 0.0002125406934891 14.4247572815534 53.19660194174757 -0.3474508055254637 0.5928702822525812 6.043665438405655 4.581801073219934 0.9191696607731276 0.3374582707438265 1.0 0.0035922663534033 0.0378446103129622 0.0139728908478156 0.0005183709376164 +Polysomal ribosome 11 26 3.692633204682275 0.0002219440230086 12.57766990291262 25.67233009708738 -0.6096975471652369 0.4252058931739489 5.190664361369856 0.8371886656600765 1.290081657729728 0.3517767491710444 1.0 0.0004528325246922 1.1389417074804347e-05 9.001864838494378e-05 1.2148269962664049e-06 +Cytosolic large ribosomal subunit 18 47 3.657623754289945 0.0002545643581381 24.944174757281555 46.19660194174757 -0.9606653080216496 0.3073733017858688 8.750550054752102 0.6518741515897012 1.9361311533291576 0.3576780745044947 1.0 0.027703186905031 1.210302617430807e-05 3.9856666021537366e-05 1.4807038952391945e-07 +Dna packaging complex 12 30 3.65257234424786 0.0002596264186329 11.567961165048544 27.186893203883496 -1.2682557115551525 0.3162623166266461 4.155677216135228 2.6506132388548593 1.3109592750478818 0.3330893937172427 1.0 1.0 1.0 0.0135656277048388 1.8042165381148847e-05 +Centriolar satellite 18 30 3.453580900374171 0.0005531963493923 6.631067961165049 24.325242718446603 0.3067804976927401 0.628129362137114 3.814866909745424 4.218089072853329 0.8031313068812725 0.3161655469328873 1.0 0.0704839558103872 0.2171594264364444 0.0673309448914971 0.0289723687417025 +Supramolecular complex 138 393 3.4311544274240084 0.0006010183503215 96.63106796116504 356.7985436893204 -0.3763213420244889 0.6291848680164166 30.433754347990455 32.363690217296 0.8820341958190486 0.3496589487311172 1.0 0.2484285601496297 0.021162471936012 6.518699498512033e-05 1.1115034225494161e-08 +Preribosome 27 69 3.409372543824655 0.0006511249557175 30.43446601941747 62.24029126213592 -1.4197947775299136 0.3409591614198546 9.966598413609615 3.609995281795233 1.4605024846200096 0.3544803128291746 1.0 1.0 0.0077976080130679 6.201784715570012e-08 3.7861247607072464e-08 +Nuclear body 117 314 3.372475030970571 0.0007449584078262 95.64077669902912 298.2305825242718 -0.8447929835161808 0.4948688964815047 29.679797440275227 28.06126682416833 1.1907301736590046 0.3417059524451045 1.0 0.0050034789868036 6.928462513152672e-06 5.209167440253565e-10 1.2625321196711375e-14 +Actomyosin 10 30 3.367674173485412 0.0007580512673277 10.78883495145631 28.148058252427184 -0.3282445360105305 0.5498108736055584 5.230750340830538 2.9918856470062476 0.9892203472825236 0.3368817507677292 1.0 0.2670314735990955 0.1267862934099702 0.0043238685287733 0.0032646848465101 +Nuclear speck 72 185 3.367190715528703 0.000759381524743 58.87621359223301 174.71844660194174 -0.7548211623268971 0.5175461188641929 19.438644256158533 15.308267628348064 1.1385271581421306 0.3421965619655378 1.0 0.0910053419471295 3.412351559094539e-05 2.954824827241769e-08 1.0913664832060334e-12 +Cytoplasmic stress granule 15 42 3.362002717429572 0.0007737936209486 16.961165048543688 44.01699029126213 0.1060948640769821 0.6180155726882541 8.213087271310163 2.534653548624787 0.9910975835660816 0.3478412307977345 1.0 1.0 0.5045129832066302 0.0077530601496985 0.0216432397728663 +Protein dna complex 21 60 3.274015167539571 0.0010603091981344 17.949029126213592 55.71116504854369 -0.9866144752706804 0.4438448685800478 7.023526624272888 4.560443216616372 1.1337955716835169 0.3589674314577153 1.0 1.0 1.0 0.1927238501074391 0.0078139570241312 +Ribonucleoprotein granule 35 108 3.209112417553745 0.0013314542265963 31.388349514563107 108.0873786407767 -0.1052892902919536 0.6662905949668418 12.160123442229802 8.26662114574696 0.8202737617387182 0.3209230511652521 1.0 1.0 0.3558190012271436 0.0173962394315872 0.0184240944570799 +Transcription regulator complex 44 90 3.1975552220978902 0.0013859787141565 22.155339805825243 76.01699029126213 -0.4564109965654688 0.6018414659270552 9.527688094103029 11.322166705309472 0.7131721054447444 0.302328683597923 1.0 1.0 1.0 0.9467785569604458 0.8522565520082785 +Nuclear periphery 22 64 3.1923441152946257 0.0014112309556393 18.12621359223301 60.40291262135922 -0.4317262988412477 0.6044085835117103 7.301655101174957 4.307680120609141 0.8037007802883803 0.3164244353162187 1.0 0.1137743690382112 0.1094639781610952 0.0699507614897222 0.0017544026492521 +Spliceosomal complex 55 134 3.177239424072465 0.0014868423433942 41.33495145631068 123.60922330097088 -0.6577090524683991 0.5162177222736225 16.862506284699407 7.165533224194126 1.3257757858163248 0.362000870587413 1.0 1.0 0.2698447817333473 4.547969133340814e-05 8.926138393905792e-07 +Atpase complex 32 50 3.119998762970456 0.0018085179945588 20.174757281553397 43.66019417475728 -1.1790885825255886 0.3782163884203613 8.034122839206324 4.443394569707038 1.1578476453281863 0.3614186576306585 1.0 1.0 0.5897423730476636 0.0699377042339779 0.0042026499143843 +Actin filament bundle 10 31 3.0144045039191085 0.0025748425593183 11.03640776699029 29.140776699029125 -0.6521861218902891 0.4783216530675612 4.9434800356481965 2.8684063060425107 1.0934322966422132 0.3459483602864249 1.0 0.2597451867723493 0.1202677732034906 0.0166068511726292 0.0026068114295301 +Fibrillar center 23 54 2.9964108517444537 0.0027317810057962 16.24757281553398 49.89320388349515 -1.3523013287928285 0.3081353469429111 6.998048891193377 4.734017816462762 0.9737289108927384 0.3179313470548497 1.0 0.453019277017924 0.031778301752159 0.0030459287372 0.0063939412457931 +U2 type spliceosomal complex 26 67 2.9818124920822893 0.0028654744246643 24.446601941747577 60.33980582524272 -1.075259266020069 0.4141933593162286 9.583286579096107 4.149051589039326 1.2129861470328036 0.3501779165484105 1.0 1.0 0.2171594264364444 0.006121125347197 9.342242278528463e-05 +I band 19 36 2.848247543272456 0.0043960716050792 9.652912621359222 30.76941747572815 -0.6571680755202443 0.4779397543084426 4.497401219618842 2.999633739856723 1.0406679246412356 0.3431166548804105 1.0 0.312708212996757 0.5285075461630524 0.1160125201978225 0.0036518848204098 +Ribosome 59 153 2.839322922857827 0.0045209379614643 55.980582524271846 138.4247572815534 -0.8588609779449204 0.4198796746336922 18.0091565612889 6.601093517039386 1.5926376724246476 0.3624017888625265 1.0 0.0003477476198268 3.895925515219643e-07 1.9228920470174407e-09 5.4062960751100335e-11 +Ribosomal subunit 51 133 2.795568422226867 0.0051808533753041 51.269417475728154 121.31067961165049 -0.8787798235149152 0.3945201412304035 16.491031297432507 6.024269888830331 1.7251057442328237 0.3662365802061124 1.0 0.0089033516550594 3.6325333758054514e-05 1.4476747612276231e-05 3.2420995773990124e-08 +Myosin complex 7 10 2.7875786691359674 0.0053103559057086 4.487864077669903 10.04368932038835 -0.3484215600090247 0.5333703531544618 2.3415512866745116 1.480630271393084 0.8964503071920732 0.3106754393041399 1.0 0.1373006943976843 0.2562935091164666 0.0363308723059728 0.0028413691736374 +Brush border 11 31 2.778223947314364 0.0054656933633483 8.446601941747574 29.148058252427184 -0.3086913029074812 0.625915343599169 3.7564912241715382 1.9421040328150696 0.7059349361820056 0.2917833116551295 1.0 0.2486824788491954 0.1106573079891401 0.0135656277048388 0.001821375794174 +Preribosome small subunit precursor 6 14 2.701879613942286 0.0068948721972699 5.0 11.439320388349516 -0.5005936622763572 0.5314450143870103 2.6603890510435915 1.1981812772195453 0.7793644898482616 0.2972683482001505 1.0 1.0 0.0104494791604543 2.980930071886438e-05 6.856302599535404e-05 +Condensed chromosome centromeric region 29 85 2.6936993279942385 0.0070663878484451 18.50485436893204 71.98543689320388 -0.2926518375269014 0.679949658980838 7.228078725786696 8.47267346726585 0.6260883942501158 0.2823011038174768 1.0 0.5242424273097586 0.1822950070070434 0.0115069392630361 3.8559900126995545e-05 +Cortical cytoskeleton 24 44 2.669354987834963 0.007599708169373 13.313106796116504 41.327669902912625 -0.3967504488871569 0.5792258339328108 5.606560222835737 3.375656916689143 0.8960447391672565 0.3321999873789645 1.0 0.3361355940595682 0.195637464602177 0.0160511047553481 0.0006470379408526 +Pml body 10 27 2.668191990167624 0.0076260666263499 7.211165048543689 23.83009708737864 -0.5079401693583121 0.5464875961436834 3.871926792859574 4.713672221932361 0.7928842441791594 0.3026033477467296 1.0 0.3394178268581344 0.5645278149470376 0.3396856282727292 0.2254780651450759 +Protein acetyltransferase complex 9 26 2.667926074511565 0.007632104901146 7.497572815533981 22.788834951456312 -0.4787364691267295 0.5572560531983579 3.743926334750418 4.697817258278194 0.7651122135340349 0.3033914984618888 1.0 1.0 0.5938019181425528 0.1841960821846619 0.0328355011999187 +Cluster of actin based cell projections 11 36 2.642811539950316 0.0082220785861533 9.182038834951456 33.03155339805825 -0.2446688552805535 0.6584579718648917 4.090406455276252 2.794146884158999 0.64099243454281 0.2763744616924541 1.0 0.3228460923172884 0.181453052630302 0.0443223277805319 0.0143284414800474 +Condensed chromosome 42 119 2.60034952516364 0.009312885181681 30.79854368932039 106.13592233009707 -0.5066057973757152 0.5964438426641788 10.283632853971191 11.394129423275642 0.7347600951076492 0.3130398307547093 1.0 0.2844506340284701 0.060045031066873 0.0066895202357141 5.570978457079206e-06 +Condensed nuclear chromosome 11 22 2.5933197374553005 0.009505435441367 7.701456310679611 20.45631067961165 -0.3401877506131432 0.6032046053963597 4.0764178325067 2.302496319548944 0.7592463825773886 0.3035818872931678 1.0 1.0 0.0636449972198752 0.2753302510648254 0.0153479918417224 +Cajal body 11 33 2.572937926202488 0.0100839291816243 11.4247572815534 32.78398058252427 -0.4891053492175548 0.5664487048507872 4.918428659141894 2.379001111997449 0.7769103516793645 0.3143184937752351 1.0 1.0 0.0981876870196897 0.0429389108076898 0.0152442441513 +Chromosome telomeric region 24 83 2.5489406808338155 0.0108050677291973 25.660194174757283 77.71601941747574 -0.7649601562617984 0.5190972663395601 10.038811477691285 5.887656635692773 0.8918806295107942 0.3435252097607013 1.0 1.0 0.3968978130303479 0.0209938797103916 0.0031313536025979 +Nuclear inclusion body 2 8 2.5254686218880296 0.0115544099257451 4.361650485436893 8.004854368932039 -0.4965885772690483 0.5338153475438098 2.120813453154777 0.49264072274246 0.8056805760848821 0.3095650369234836 1.0 0.0573151884822011 0.1116045715736199 0.0027195691326621 0.0182159139614431 +Microtubule plus end 9 12 2.5165918879888096 0.0118495996910192 3.5485436893203883 8.817961165048544 -0.3583017371053751 0.5300786537653812 2.0372913713031795 1.2840952836612138 0.8646642934210481 0.3038731198332685 1.0 1.0 0.1709159600444602 0.3763073460681103 0.0120515986398723 +Microtubule associated complex 26 53 2.5144215160855694 0.0119227836695792 13.50485436893204 47.66990291262136 0.0924712472826301 0.6540803251543599 6.046540833133665 6.245601713788117 0.8846152481627416 0.3231371254728546 1.0 1.0 0.1053672202985524 0.155906858032705 0.2045307840380992 +Spindle pole 32 66 2.506073077852049 0.0122080385388883 15.512135922330096 55.34708737864078 -0.2869819394232706 0.6781163045417219 6.370620391743639 6.832135393923972 0.6329484684598604 0.2885854586936718 1.0 0.50487672715324 0.1629635375300463 0.6811167378879559 0.0211159960406443 +Cell cortex 31 109 2.504449737359309 0.012264202944503 27.75728155339806 97.37864077669904 -0.5710640031257539 0.5505847619578526 10.162720776491 9.909166595558451 0.9184054194288116 0.3438636855368586 1.0 0.681327455599611 0.663657041087893 0.0262416214782407 6.84111717042886e-06 +Actin cytoskeleton 56 144 2.4810363669958915 0.0131001006871216 38.366504854368934 134.15776699029126 -0.7052760727227785 0.5219806162937325 14.593659496257096 12.061406914669634 1.122519962565386 0.3602623503391778 1.0 0.0954360750806307 0.2688251840925229 0.0064796793339162 2.3025657015176592e-05 +Neuron projection membrane 6 10 2.4809484150241885 0.013103333452471 2.9611650485436893 8.16504854368932 0.1778845474417817 0.56224999551785 1.960395888773526 1.6814065273647745 0.8566859366775101 0.3007753284948182 1.0 1.0 1.0 0.4065747127007614 0.2730711037423907 +Microtubule end 9 14 2.445821822009348 0.0144522403270452 3.8398058252427183 9.949029126213592 -0.3375067492265889 0.5371528660566897 2.2073504657849456 1.5902689609256988 0.8617921103913576 0.3021140457871507 1.0 1.0 0.2263045436956677 0.4759945765538561 0.0355737118947821 +Multivesicular body membrane 6 9 2.436360760412052 0.0148358799659402 2.2597087378640777 5.703883495145631 -0.0909344370751552 0.5093211865371587 1.6289337487708992 2.277940746525038 1.0118959680768935 0.3083397222188037 1.0 1.0 1.0 0.0179536348510701 0.0043704316922178 +Mitotic spindle 22 74 2.359020400626561 0.0183232484306044 18.47087378640777 64.26699029126213 -0.3802860332021146 0.6693621971428984 7.350888342960467 7.80723946276992 0.6600681584078645 0.3070186165835232 1.0 1.0 0.0496921697164348 0.2644700061270317 0.0035910010540877 +Adherens junction 24 48 2.3364110272839564 0.0194698297779898 12.308252427184469 45.54126213592233 -0.2059641721105205 0.6094088431010728 7.035598100752319 5.26582186941516 0.8273120663650774 0.3159855429819956 1.0 1.0 1.0 0.3954469149758929 0.1833350276114758 +Centriole 5 32 2.331743811233643 0.0197141725451353 7.177184466019417 25.56553398058253 -0.0477360182303363 0.6746277013913514 4.101877836004659 4.604564689197087 0.674226498955594 0.2826723776990107 1.0 0.1137743690382112 0.1094639781610952 0.0699507614897222 0.3525871576110326 +Heterochromatin 14 36 2.330583279214462 0.0197753440194625 12.223300970873789 31.616504854368937 -1.0889296505821056 0.3815946815849076 5.437521634970822 3.948518146209703 1.0871408858971054 0.3524651940838824 1.0 0.2813938178053637 0.1400650262765533 0.0817548825121617 0.0156922549658499 +Precatalytic spliceosome 10 39 2.3013908727507206 0.0213695473632631 15.631067961165048 34.63106796116505 -1.218986301461536 0.3568515135168387 6.033869278589771 2.331674223535884 1.0645858751207695 0.3362981089944576 1.0 1.0 0.0921147949975289 0.0381586751774073 0.0008152365052425 +Nuclear pore nuclear basket 4 10 2.2848576270585124 0.022321177319551 2.6019417475728157 7.330097087378641 -0.0421653127362139 0.564640288305229 1.9047197680144203 1.2058783972775375 0.8958694288159871 0.3003224491484906 1.0 0.0573151884822011 0.000188873280149 5.858632531004144e-06 0.000160552482799 +Transcription repressor complex 5 15 2.2648641931499824 0.0235210146831441 5.262135922330097 14.429611650485436 -0.5431273390729503 0.5393542708833129 3.0805092412470727 1.9650827806027784 0.7386580166986962 0.2994423871224635 1.0 1.0 1.0 1.0 0.6204077015109344 +Box c d rnp complex 2 6 2.248860416640313 0.0245213780739557 3.5024271844660193 5.798543689320389 -0.9906091703429662 0.3189702123363987 1.6347245045765195 0.4783647464179557 0.9336732718428123 0.2803998812505426 1.0 1.0 1.0 0.0115925044366013 0.0034775277607499 +Sm like protein family complex 19 53 2.23206283890616 0.0256108100577072 20.32766990291262 49.842233009708735 -1.0109308840679758 0.4225503229099085 7.470453866962472 3.2113063101409582 1.0331863080790435 0.3507144637016726 1.0 1.0 0.0372017462297913 0.2790882191036065 0.0009530352748587 +Ciliary transition zone 4 11 2.2176634128748143 0.0265777906579955 1.9635922330097089 6.907766990291262 0.9295898692526422 0.3532985326295446 1.5457849700174688 1.7711928579014855 0.854807445224746 0.2896111184937897 1.0 0.0267403422938185 0.0142951840993497 0.0381586751774073 0.1079287008920704 +Neuron to neuron synapse 30 70 2.211294713358704 0.0270154352094897 13.283980582524272 62.51699029126213 0.0452447961299691 0.7244268272439499 6.738487894655527 6.035670880729685 0.6463748499647565 0.2876123842093391 1.0 0.2881021086306851 0.6320748637382985 0.2835474938305009 0.3685313607212144 +H4 h2a histone acetyltransferase complex 3 9 2.2110195614759 0.0270344824828905 3.6601941747572817 8.62621359223301 -0.633789435951199 0.4943082099871211 1.9844218451185076 1.9336298761830504 0.7721172757385433 0.2967992868007946 1.0 1.0 1.0 0.1162426898263886 0.0272826327042602 +Cleavage furrow 7 22 2.205479417193012 0.0274204705768918 5.116504854368932 18.439320388349515 -0.143923511325495 0.6334420390469166 3.135456396297552 2.9491989243537913 0.7683805141101449 0.295048930148392 1.0 1.0 0.3460310778663031 0.0878701351278624 0.0043866153154496 +Iswi type complex 6 10 2.1956316680717025 0.0281183176724435 4.563106796116505 8.728155339805825 -0.7730717618719684 0.4043799389808893 2.24330677778903 1.487450250500569 0.934742152904809 0.3082208658429738 1.0 1.0 1.0 0.0390924086837951 0.0028040242445346 +Pronucleus 1 6 2.1927061555691365 0.0283285569627524 1.837378640776699 5.065533980582524 -0.1358519228012729 0.5841499511840532 1.3384750496639486 1.3322280251448109 0.8419526273173533 0.303620125657057 1.0 1.0 1.0 0.2390677645130265 0.0974859568290139 +Cell cell junction 44 121 2.1803091662648946 0.0292345520704502 26.053398058252423 108.90776699029126 -0.2569312511624391 0.6234868006154447 10.868903853538864 10.886494611057328 0.8320790781958789 0.3243713173268808 1.0 0.7925637171352815 0.8198335119212635 0.1517005024199187 0.0199602250205894 +Nuclear chromosome 42 99 2.180047843321115 0.0292539153114839 30.54368932038835 88.82766990291262 -0.6980854906634841 0.5358536668591611 11.832591734933397 8.539281671420111 0.889349938575182 0.3397613341184241 1.0 1.0 0.238185905219404 0.612479042631509 0.0207543331542711 +Cortical actin cytoskeleton 18 33 2.123540422311351 0.0337085919595807 10.53883495145631 31.643203883495147 -0.3594638047595956 0.5800413238126021 5.306247151880192 2.6569888473854286 0.8673378709456674 0.3285524765020431 1.0 0.2742474624411909 0.4741193373633443 0.0749307774450376 0.0040466728259346 +Nbaf complex 6 8 2.1224398468010133 0.0338008190382033 3.9975728155339807 7.390776699029126 -0.627739285247984 0.4719801811520063 2.0307093628933113 0.7072525665242388 0.8754194001065545 0.3138253419147213 1.0 1.0 1.0 1.0 0.4779737602264646 +Filamentous actin 4 10 2.1083582510569028 0.0350000128018714 4.827669902912621 9.351941747572816 -0.613340208073223 0.4804474814047199 2.479412592461624 1.7320286989776996 0.8033536790483101 0.3079869609141683 1.0 1.0 1.0 0.0039718755498612 0.0089325963600969 +T tubule 2 8 2.07566796640018 0.0379246706116354 2.254854368932039 6.992718446601942 -0.0168954028360724 0.6160410509097547 1.5266565817489597 1.1136598408473002 0.7532116703329593 0.2818014965765905 1.0 0.1201219647894398 0.0265618978442646 0.1326788571378727 0.1309583783231107 +Immunological synapse 5 14 2.0643635601652943 0.0389832587655716 4.216019417475728 12.970873786407768 0.0261094749988883 0.6847315469227506 2.599371783628859 1.3105717323456687 0.6457960051099476 0.2703638067145371 1.0 1.0 1.0 0.4353788157626653 0.3097803043008575 +U1 snrnp 7 11 2.058774733098128 0.0395158232145191 5.240291262135922 11.490291262135925 -0.903579393495105 0.3790889149400443 2.4471159789015915 0.9565324271023994 0.8523907571553603 0.2964137297882449 1.0 1.0 0.1543818096433915 0.3445026949300507 0.0079931710216612 +Spliceosomal snrnp complex 16 43 2.0460204464017493 0.0407543590617747 18.1626213592233 41.47330097087379 -1.128624172705727 0.3824038000335636 6.926469625862109 2.3825347065390536 1.0666594993374927 0.3462824091290538 1.0 1.0 0.1043706933170995 0.4007853524207055 0.0003251864982136 +Prespliceosome 4 10 2.04235916164127 0.0411159175557673 4.288834951456311 10.12135922330097 -0.217169716838055 0.6014216099199682 2.7273465183235164 1.0993511312558748 0.7990171517042967 0.2986317091115096 1.0 1.0 1.0 1.0 0.0338099842169397 +Cell division site 8 29 2.0359539833597395 0.0417549762676827 6.575242718446602 23.87135922330097 -0.1787254876817006 0.6533057712498949 3.657903889308445 3.832089229291234 0.729519701824541 0.2890068816795109 1.0 1.0 0.4363210249842685 0.1696751373461712 0.0219335059982234 +Costamere 3 6 2.02727998825546 0.0426337868859612 2.703883495145631 6.189320388349515 -0.407604998997626 0.5212516523616547 1.660414168130226 0.6484354016915174 0.9017950607398544 0.3145848777869111 1.0 0.066549445548378 0.1289666473793992 0.0448845799435813 0.0280386150660574 +Chromosome centromeric region 36 110 2.026042095571577 0.0427604710536875 25.25485436893204 93.79126213592232 -0.4084312679355601 0.6434617258278953 8.816940926925206 9.809601070598868 0.6458226267851661 0.3011063159484605 1.0 0.6257786575609776 0.3073420480660703 0.0095520215634986 9.407281653998189e-05 +Histone deacetylase complex 11 28 2.015670850287724 0.0438344056818382 10.393203883495143 25.174757281553397 -0.807065544725226 0.4675458531924047 4.564080148201631 3.642193898929385 0.8531422701751867 0.3277106708886297 1.0 1.0 1.0 0.0888749025390611 0.1190263460182328 +Mitochondrial large ribosomal subunit 20 37 2.006508489974496 0.0448020238609676 8.633495145631068 29.555825242718445 -0.1481080091052014 0.5841135377138064 5.916009578876211 3.943692278182195 0.9731710590444376 0.3301980233297082 1.0 0.027703186905031 0.0951370618475993 0.040508503274826 0.043045103354355 +Dendrite cytoplasm 7 11 2.004347286892787 0.045032871761748 2.779126213592233 10.820388349514564 0.6421759346520178 0.4909623397232819 2.094201707070112 0.8165591106732504 0.7456922507906857 0.2969723837010567 1.0 1.0 1.0 0.4353788157626653 0.09905667817091 +Ruffle 18 63 2.000516617491983 0.0454445073531855 15.04126213592233 56.72572815533981 -0.1679851010938298 0.6228095460865153 7.608486980679421 5.714911359630224 0.8325885344199131 0.3160947354154053 1.0 1.0 0.7722229142029041 0.0737970915743952 0.0138936167958461 +U2 type catalytic step 2 spliceosome 9 25 1.9965035236165205 0.0458791426008602 11.516990291262136 24.106796116504853 -1.097449100572703 0.3683224816492141 4.527928722326451 1.522725082501146 0.9889872576423064 0.3359989305150568 1.0 1.0 0.2562935091164666 0.0058563460560428 0.0139902560164694 +Nuclear pore 10 55 1.9883301922695569 0.0467751837200738 12.91504854368932 48.820388349514566 -0.273035189230828 0.7376315994783034 6.089547526320278 3.257071745301141 0.5453276411277703 0.2702770180883928 1.0 0.0584635742500571 0.0077976080130679 2.3912366142308967e-05 0.0016376917698255 +Rna polymerase ii transcription regulator complex 22 41 1.988314480588852 0.0467769202697854 9.514563106796116 33.20631067961165 -0.2291804652602324 0.6558042250460213 4.9578105049809125 6.626561657347179 0.6759718727501905 0.2900534180522208 1.0 1.0 1.0 1.0 0.9945197163166176 +Sex chromosome 7 13 1.9737852762357069 0.0484061637383566 5.536407766990291 11.308252427184469 -1.0422975319180567 0.3478319985962729 2.549725800741876 1.3687319105933904 0.910433867771836 0.3112350931926583 1.0 1.0 1.0 1.0 0.3280048671308403 +Paraspeckles 3 6 1.970353380369115 0.0487978845871071 2.900485436893204 5.966019417475728 0.4401658585922723 0.518297360446682 1.415002747014917 0.1811792000633157 0.8461530257321199 0.3151127677442134 1.0 1.0 1.0 1.0 0.2591162943571684 +H4 histone acetyltransferase complex 4 12 1.9693434874138496 0.0489136605492555 5.485436893203883 11.822815533980584 -0.8199137524456892 0.428730154982415 2.6157256977040197 2.1531561469519005 0.7726090847086151 0.3018152465614572 1.0 1.0 1.0 0.229635410858896 0.0324377486516598 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0cfa37fd1d35ab157c3d60970898be8786db2ced --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 912, + "title": "Average number of proteins per term", + "value": 32.23135964912281 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2701e6537160ea3444778aa45e7cd5de42b002fc --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..996f564092de71679897404585d7d13eb8fac773 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,391 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nuclear protein containing complex 0.3492457218582018 6.619062168369097 3.614848160326729e-11 3.296741559135037e-08 1.6483708067089883e-08 530 Q96ST3,Q9Y3C6,Q12834,Q8TD16,P38159,P20585,P49790,Q92541,Q15233,Q05048,P52272,P25205,O75528,Q13523,P55735,Q9H981,Q86V81,P08579,P43487,Q92878,O43290,P25490,Q7L2J0,Q9Y6D9,P23246,Q9ULR0,Q9UBW8,Q9NPE3,Q9NPA8,Q9BRX5,P78316,Q9HCK8,Q13769,Q9NYF8,O43395,O14802,Q9UEE9,P82979,Q9UQ35,Q01130,Q8N201,Q9Y2W2,Q96DF8,O00159,Q9NRF9,Q9H307,Q96EE3,Q15906,Q15014,Q9UQN3,O60832,Q13573,P13984,P24928,P98179,Q96E39,Q86YP4,Q15637,Q92922,P18887,Q14157,Q99627,Q9H2H8,Q9HD42,Q9NR30,Q9UIG0,Q6UX04,Q9P013,P12270,Q16576,O75400,O75446,O60934,P29083,Q9Y2W1,Q8WXI9,Q7Z3B4,Q9NYB0,Q9NZZ3,P35658,Q9H444,Q15910,P08621,P16383,P17096,P19338,Q99459,Q969X6,Q96EB6,Q9NRL2,Q7LBC6,Q9C0J8,Q92917,Q8NFH5,O94776,P55081,P11940,P17544,O00566,Q9BW85,Q02040,P18615,Q15291,Q9UBT2,Q14978,Q9Y3Y2,O94992,P11142,Q6UN15,Q15459,P45973,Q9Y3E7,Q9NPF5,Q14331,Q92785,Q15648,O15160,P09012,P11802,O95983,Q13435,Q9HAF1,Q71SY5,Q8IXM2,Q8WYA6,Q14241,Q969G3,Q12830,Q9H6R4,P62314,Q9NVC6,Q9NW13,P35269,P41223,Q14137,O95400,Q9UM54,Q13185,Q9Y383,Q9H2P0,Q6ZRS2,P55769,Q9BUQ8,P21333,Q14683,Q9NQG5,Q13123,Q9UNS1,Q96T23,Q8WUB8,Q12972,O95232,Q9UQE7,Q9UPT9,Q9HAU5,Q99496,P33991,Q9H0H0,Q13416,P49916,P51610,Q9UHI6,Q9BZI7,P51991,P33240,O94880 166 +Chromosome 0.3715761898614156 6.112599035141716 9.802143819233684e-10 8.939551180861313e-07 1.787911034452224e-07 479 Q96ST3,P46013,Q8WYP5,Q15059,O75150,P38159,P51784,Q14676,Q15233,Q7Z6E9,P25205,Q9NZM5,Q13523,O14974,P55735,Q9H981,Q86V81,Q92878,Q9NQS7,P25490,P23246,Q9Y6D9,Q8IY81,Q14980,Q9H6F5,Q9UNZ2,Q9BRX5,Q99848,Q13111,P54132,Q13769,Q96L73,Q9UEE9,Q5SSJ5,P05204,O43237,P42696,P53990,P55072,Q9NRF9,Q5QJE6,Q15906,Q96EE3,Q6PK04,Q8WVB6,Q15014,Q9UQN3,O60885,P11387,P51608,O94842,Q9Y237,P24928,Q86YP4,Q92922,P18887,Q9HD42,Q9NR30,Q9UIG0,P62805,Q9UER7,Q7Z3K3,P12270,Q16576,P16402,O60934,Q14141,Q8WXI9,Q96JM3,Q15050,Q9NYB0,Q9NZZ3,Q9H444,Q15910,P05114,P17096,P19338,P26358,Q76FK4,Q969X6,Q96EB6,Q99640,Q9H3R5,Q14807,Q9NRL2,Q7LBC6,Q92522,Q9Y6G9,O94776,P05455,P17544,P26583,O00566,Q9UMY1,Q14692,P22314,P23258,P45973,Q9NRZ9,Q8NC56,Q9Y3E7,Q9NPF5,O75179,Q92785,P11802,O95983,Q9Y448,Q9HAF1,Q8IXM2,Q14241,Q969G3,Q12830,O75683,Q9H6R4,P35251,Q96QE3,P41223,P16403,P16104,P10412,P07305,Q14137,Q9NY93,Q96IZ0,Q13185,Q15019,Q9H2P0,Q6ZRS2,P54652,Q9BUQ8,O95347,Q8NBT2,Q14683,O95747,O15347,Q13123,Q9UNS1,P39748,Q15435,Q96T23,Q96QC0,Q8WUB8,P80723,Q96GQ7,Q7Z7K6,Q14008,P59998,Q14203,Q01664,Q9UQE7,Q99496,P02545,P33991,Q9Y4C8,Q96T60,O75475,Q13416,P09874,Q9H1E3,Q9BRT6,Q9P0M6,P25440,Q13112 163 +Ribonucleoprotein complex 0.400823115467162 5.689146967241281 1.2767555087644998e-08 1.1643942523952022e-05 1.5416783256955424e-06 458 Q9Y3C6,Q8IXT5,Q6PKG0,O95319,P38159,P83731,Q2NL82,Q9Y3B9,Q9NZI8,P62917,P84098,Q9NQ50,P20290,P52272,Q13523,P62841,Q12906,P52815,Q86V81,P47914,P08579,O43290,P06748,P0DMV9,Q7L2J0,Q9ULR0,Q8IY81,P62424,Q9NPE3,P62750,Q99848,P78316,P62081,P62899,Q14197,Q9ULX3,Q9H9Y2,Q8IXM3,O43395,Q9UQ35,Q01130,Q9Y2W2,Q96GA3,Q9BYD3,Q96DF8,P40429,Q6P1L8,Q7Z417,Q8NEF9,Q9H307,Q9BSC4,O60832,Q13573,P98179,Q96E39,Q15637,Q9H2H8,Q5T653,Q6UX04,Q9P013,O75400,Q15050,Q9H814,Q9NTZ6,Q6PJT7,P46778,Q9BYN8,P82912,P61254,P16383,P19338,P08621,Q99459,Q9BTD8,Q969X6,O43818,Q9NSI2,Q9P015,Q13310,P46779,P61353,Q92917,P05455,P46782,P55081,P11940,P62263,P83881,O00566,Q02040,Q9BW85,Q96GC5,Q969S3,Q14978,Q14692,P82650,P82673,O94992,P11142,Q15459,P45973,Q13283,Q14331,P62913,P46940,Q9H7N4,P09012,P26373,P61247,P50914,Q13435,Q8WYA6,Q9BRJ2,Q9GZT3,Q9H6R4,P62314,Q00341,Q9NW13,Q9BVJ6,P41223,P46776,Q13405,Q14137,O95400,Q14690,Q96A35,Q9Y291,Q9Y2R9,P62857,Q8N9T8,P35580,P39019,Q9Y383,Q86U38,P04406,Q96PK6,P36578,Q12849,P55769,Q9BUQ8,Q9UN86,O75691,P62847,Q01081,Q13084,Q9BXP5,Q9UKM9,Q9Y3B4,Q13123,Q9NV06,P07814,Q9BYD2,Q12972,Q02878,Q9Y3B7,P19474,P61011,P62304,O15213,P62753,Q00839,O95232,Q96I25,Q9HAU5,Q96NC0,Q9NRX2,Q9NW64,P62273,Q9UJV9,P46777,O75821,P05387,Q92499,P51991 174 +Nucleolus 0.380163978411509 4.620301566075602 3.83182675434135e-06 0.0034885335733392 0.000349462599996 449 Q96ST3,Q9GZR2,P46013,P49790,Q2NL82,Q92541,Q15233,Q7Z6E9,Q9P2D1,P84098,Q9NQ50,P52272,Q66PJ3,P25205,Q9NZM5,P17480,O14974,P25685,Q12906,Q9NVU7,Q9UIJ7,P61088,P08579,Q99590,P06748,Q8IY81,P62424,Q9NPE3,Q9H6F5,P62750,Q99848,P78316,P62081,P54132,Q01082,Q9H9Y2,Q7L014,Q13428,P14373,P22059,P40429,P42696,Q5M775,O00159,Q5QJE6,Q6PK04,Q15014,Q9BSC4,O60869,O60832,P11387,P24928,Q9Y237,Q9P0K7,Q99543,Q8TDD1,P18887,Q9NR30,Q9UIG0,Q9UER7,P26599,O60934,O43709,P68402,Q9Y5K6,Q15050,Q16881,Q9UHA3,Q6PJT7,P53999,P61254,P16383,P19338,Q76FK4,Q969X6,Q96EB6,O43818,Q9H3R5,Q99640,Q9NSI2,Q9H501,Q92522,Q5JTH9,P61353,Q9C0J8,Q5F1R6,P62263,P26583,O00566,Q15291,Q9UMY1,Q9H7Z3,Q969S3,Q9GZR7,Q14978,Q14692,Q9Y3Y2,P11142,P45973,Q9BQ39,Q14331,P62913,P46087,O75347,Q15648,O15160,Q92665,P11802,P26373,P61247,Q13243,Q96DE0,Q9HAF1,O75683,Q9H6R4,Q9NXV6,Q9NW13,Q9BVJ6,P35251,Q01844,Q14137,O95400,Q14690,Q8WXF1,Q5T3I0,P39019,Q86U38,Q96PK6,P55769,Q9BUQ8,P21333,O95347,Q8NBT2,Q9Y3C1,Q9NV06,P39748,P15311,Q1ED39,Q99547,Q96GQ7,Q6P1N0,Q14008,O15213,P62753,P46777,Q9Y4C8,Q96T60,P09874,Q9H1E3,Q9BZI7,Q9BRT6,Q96RQ1 152 +Cytosolic ribosome 0.4841307667719432 4.299922698003284 1.7085769627556147e-05 0.0154615782675039 0.0012985184916943 79 P62913,P83731,P61247,P26373,P50914,P62917,P84098,P62841,Q02878,P47914,P46776,P46778,P62753,P82912,P61254,P62424,P62750,P62273,P62081,P62899,P62857,P46777,P39019,P46779,P61353,P46782,P62263,P83881,P36578,P05387,P40429 31 +Large ribosomal subunit 0.4701069884130222 4.106377773243619 4.0191197573147264e-05 0.0359914439090929 0.0022908982616694 84 P62913,P83731,Q5T653,P26373,P50914,Q9BYD2,P62917,P84098,Q9NQ50,Q9BRJ2,P52815,Q02878,Q9Y3B7,P47914,P46776,P46778,Q13405,P61254,P62424,Q96A35,P62750,P62899,Q9P015,P46777,Q14197,P46779,P61353,Q8IXM3,P83881,P36578,P05387,Q96GC5,Q9BYD3,P40429,Q6P1L8 35 +Catalytic step 2 spliceosome 0.4702945848849396 3.7715854662618384 0.0001622135782675 0.137526438187476 0.0073969391689985 73 Q9Y3C6,Q13573,Q9UKM9,Q14331,Q9Y3B4,P38159,Q9H2H8,Q6UX04,Q9P013,Q13435,P52272,Q13523,P62314,Q86V81,P08579,P62304,P41223,Q00839,O43290,Q9ULR0,Q99459,Q9NW64,P11940,Q9UQ35,Q9BUQ8,Q96DF8,P51991,Q15459,Q9H307,Q01081 30 +Polysome 0.5450073436257352 3.745589452574382 0.0001799707038645 0.1513836278650626 0.0078158705678319 47 P62917,P84098,P20290,P62424,Q6PKG0,Q9HAU5,P62913,P62273,Q02878,Q00341,P62857,P62899,P35580,Q7Z417,P62753 15 +Contractile fiber 0.5023596864528701 3.703624623142065 0.0002125406934891 0.1762248928320134 0.0084277005418324 61 Q9Y281,Q14331,Q05682,O00151,Q13049,Q96HC4,P18206,O75147,Q09666,Q9ULV4,O14974,P06733,P67936,P62942,P49257,O75369,Q9NYL9,Q16527,Q01082,Q15149,Q5VU43,Q9NR12,P11166,O75298,O75190,Q14315,P21333 27 +Polysomal ribosome 0.6483216601279045 3.692633204682275 0.0002219440230086 0.1832607695774909 0.0084338728743298 26 P62917,P84098,P20290,P62424,Q6PKG0,P62913,P62273,Q02878,P62857,P62899,Q7Z417 11 +Cytosolic large ribosomal subunit 0.5365407696802507 3.6576237542899457 0.0002545643581381 0.2072063057834398 0.0091068959151259 47 P50914,P62917,P84098,P61254,P62424,P05387,P46778,P62750,P62913,P83731,Q02878,P62899,P46777,P40429,P47914,P46779,P61353,P26373 18 +Dna packaging complex 0.6144433598752067 3.65257234424786 0.0002596264186329 0.2108588179579975 0.0091068959151259 30 P16403,P16104,P10412,Q15014,Q9HAF1,P07305,P16402,Q9NPF5,Q5SSJ5,Q92522,O95347,Q15906 12 +Centriolar satellite 0.59096443480272 3.453580900374171 0.0005531963493923 0.3962859800517366 0.0173970714015794 30 Q14498,Q9UPN4,Q9Y448,Q86VS8,Q13045,Q8WXW3,Q9Y5K6,O60271,Q9Y6A5,Q9BZI7,Q71F23,Q15154,Q7Z4H7,O15078,Q15398,P36957,P33176,O75955 18 +Supramolecular complex 0.4123093477179901 3.4311544274240084 0.0006010183503215 0.4220647953273033 0.0182709578497754 393 Q96ST3,Q8WYP5,Q6PKG0,Q05682,Q7Z406,Q96CS2,Q9BRK0,Q13049,Q6SZW1,Q92974,Q9NZI8,Q09666,O14974,Q8IZD4,P55735,Q9BSJ2,Q9Y520,P08579,P48681,Q9NQS7,Q13409,Q9Y6D9,Q9P270,P27816,Q14980,Q9BY77,Q96EY1,Q01082,Q15149,Q7L2E3,Q9NR12,Q9UEE9,P82979,P17980,O43237,Q14315,P55072,Q5M775,O00159,Q9UQB8,Q7Z417,Q9H307,Q96EE3,Q96ED9,Q9Y281,Q8WWM7,Q13464,Q5T6F2,P04083,Q9UQN3,P11387,Q14157,Q9HD42,Q96HC4,O75147,P12270,O75175,Q9Y5K6,Q02241,Q14141,Q14444,Q96JM3,Q86VS8,Q9NZZ3,Q01085,O43795,Q9H444,P49257,P19338,Q9H3R5,Q14807,Q9NYL9,Q9ULW0,Q9Y6G9,P35579,P46779,Q13310,P55081,P11940,O95793,Q9Y496,Q9Y3Y2,O75116,Q8NCM8,P23258,P45973,P46821,P07197,Q13283,Q9Y3E7,Q9H0H5,Q14331,Q9UHD8,O75347,Q7Z4H7,P46940,O15344,P50402,P18206,Q9Y448,Q9HAF1,Q4VCS5,Q9ULV4,P16949,Q15555,O00165,Q9UM54,Q6P2E9,O75369,P35580,Q15019,Q5VU43,P11166,Q12849,O75298,O75190,Q08379,P21333,Q8NBT2,Q14683,Q8WWK9,Q03252,P33176,P15311,Q02878,Q7Z7K6,Q14008,Q14247,P62753,Q14203,Q9HAU5,P02545,P58107,Q13416,Q9HC35,Q92499,P51991,O60828 138 +Preribosome 0.456403077082304 3.409372543824655 0.0006511249557175 0.4478962906121954 0.0191556761165925 69 Q9BSC4,Q9NV06,Q2NL82,Q9Y3B9,Q15050,Q9H6R4,Q9BVJ6,O15213,Q14137,Q14690,Q8IY81,Q969X6,Q99848,O43818,P78316,P62081,Q9NSI2,Q8N9T8,Q9ULX3,Q86U38,Q9H9Y2,O00566,P55769,Q969S3,Q96GA3,Q14692,Q8NEF9 27 +Nuclear body 0.4755838388266534 3.372475030970571 0.0007449584078262 0.4932083247779835 0.0196027717306991 314 Q9UBW7,Q9GZR2,P46013,Q9NWH9,Q14151,Q14676,Q9UNF0,Q15233,Q7Z6E9,P52272,Q66PJ3,Q6P6C2,Q14966,Q13523,P98175,Q9UIJ7,Q86V81,P08579,Q9NQS7,Q99590,O43290,P0DMV9,P23246,Q96T37,Q08170,O14776,Q9NPE3,Q9BY77,P54132,Q9NYF8,Q92733,Q7L014,O43395,Q9UQ35,P82979,Q15007,Q01130,Q5SSJ5,P55196,O75494,P14373,O00159,Q7Z417,Q9H307,Q15906,Q8WWM7,O60832,Q13573,Q86YP4,Q15637,Q9UIG0,Q9UER7,Q9P013,O75400,O60934,Q9Y2W1,Q8WXI9,Q96JM3,Q13043,Q9H814,Q6PJT7,Q9NYB0,Q8WW12,P08621,P49750,Q99459,Q96EB6,Q14807,Q14498,Q02040,Q15287,P18615,Q9H7Z3,Q14978,Q9Y3Y2,Q05519,Q15459,P45973,Q9BW91,Q14331,P35611,Q13435,Q86XP3,Q01844,P16104,P07305,O95400,Q8WXF1,Q9Y383,Q6ZRS2,Q96PK6,P49756,Q53F19,Q8N3X1,Q16513,P18583,Q13123,Q13427,Q96QC0,P41214,Q13526,Q12972,P61956,P80723,O95232,Q9UKV3,Q99496,P02545,Q9Y4C8,P29401,P09874,P42345,Q9UHI6,Q92499,P33240,P25440,O60828 117 +Actomyosin 0.5809725883726783 3.367674173485412 0.0007580512673277 0.4992282772406774 0.0196027717306991 30 Q92614,Q15942,Q9UHB6,Q7Z406,O75369,P35580,O00159,P35579,Q96HC4,Q9Y5S2 10 +Nuclear speck 0.491245226180682 3.367190715528703 0.000759381524743 0.4998359032289617 0.0196027717306991 185 Q8WWM7,Q9GZR2,Q8N3X1,Q13573,P18583,Q86YP4,Q13123,Q13427,Q9UNF0,Q15233,Q7Z6E9,Q9P013,Q13435,O75400,Q66PJ3,Q6P6C2,Q9Y2W1,Q14966,Q13523,Q8WXI9,Q13526,Q12972,P98175,P80723,Q9UIJ7,Q86V81,P08579,Q6PJT7,O43290,Q86XP3,P16104,P0DMV9,P23246,Q96T37,Q08170,O14776,P08621,O95400,O95232,Q9UKV3,P49750,Q99459,Q8WXF1,Q9BY77,Q14807,P02545,Q9Y383,Q9Y4C8,Q9NYF8,Q92733,Q7L014,Q14498,Q96PK6,O43395,Q02040,Q9UQ35,Q15007,P82979,Q01130,Q5SSJ5,P55196,O75494,Q15287,Q9H7Z3,P49756,Q05519,P25440,Q53F19,O60828,Q9H307,Q15459,Q15906 72 +Cytoplasmic stress granule 0.5301842916336159 3.362002717429572 0.0007737936209486 0.5063719379625693 0.0196027717306991 42 Q8WWM7,Q13464,Q13283,P11940,O95793,Q6PKG0,Q14444,Q92499,Q14157,Q9Y520,P55072,O60828,Q7Z417,Q9NZI8,Q01085 15 +Protein dna complex 0.4690139362498284 3.274015167539571 0.0010603091981344 0.6199737736468737 0.0254474207552277 60 Q15014,Q9NPF5,P11387,P13984,P62805,Q9HAF1,P25205,P16402,P29083,P06748,P16104,P16403,P07305,P10412,Q9BRX5,P33991,Q92522,P09874,Q5SSJ5,Q9P0M6,Q15906 21 +Ribonucleoprotein granule 0.4331498571183916 3.209112417553745 0.0013314542265963 0.7033182774983957 0.0286009473676237 108 Q8WWM7,Q13464,Q5T6F2,Q13283,Q6PKG0,P11387,Q14157,Q9NZI8,O75175,Q14444,Q8IZD4,Q02878,Q9Y520,P08579,Q01085,P62753,P19338,Q9HAU5,Q6P2E9,Q9BY77,Q13310,P46779,Q7L2E3,P11940,Q12849,O95793,P82979,P17980,Q9Y3Y2,Q92499,P51991,P55072,O75116,O60828,Q7Z417 35 +Transcription regulator complex 0.4146301805829252 3.1975552220978902 0.0013859787141565 0.7177294708817828 0.0286009473676237 90 Q96ST3,P45973,Q9NPJ6,P13984,Q14839,Q86YP4,Q15648,Q9H7N4,O00151,P51858,O95983,P11802,Q15233,P23193,Q71SY5,Q16576,Q9H1I8,Q8IUF8,O75528,P29083,Q8WUA4,Q8WXI9,Q9NY61,Q6IAN0,Q9NVC6,P53999,P35269,O00165,P25490,Q13503,P23246,P07305,Q01664,P17096,Q13185,Q9H2P0,P32780,O94776,P17544,Q96PK6,P09874,Q9UHI6,Q9Y5Q8,Q15650 44 +Nuclear periphery 0.4533106754563303 3.1923441152946257 0.0014112309556393 0.7241647864875407 0.0286009473676237 64 Q9Y281,Q8WYP5,Q13573,Q05682,P49790,Q9HD42,Q13427,Q15233,P12270,P52272,P80723,P25490,P23246,Q9UQE7,Q14980,Q8WXF1,Q99848,P02545,P54132,P43243,Q5BKZ1,Q14683 22 +Spliceosomal complex 0.4522456999664647 3.177239424072465 0.0014868423433942 0.742570477867655 0.0294782655907728 134 Q9Y3C6,P11142,Q13573,Q14331,Q9UKM9,P98179,Q9Y3B4,P38159,Q96E39,Q15637,Q01081,Q13123,Q9H2H8,P09012,Q6UX04,Q9P013,Q13435,O75400,P52272,Q8WYA6,Q13523,Q12972,P62314,Q86V81,Q9NW13,P08579,P41223,O43290,P62304,Q00839,O95232,Q9ULR0,P08621,P16383,Q96I25,P19338,Q96NC0,Q99459,Q9NW64,Q9Y383,Q92917,P55081,P11940,O43395,Q02040,Q9UQ35,Q9BW85,Q01130,P55769,Q9Y2W2,Q9BUQ8,Q96DF8,P51991,Q9H307,Q15459 55 +Atpase complex 0.4723901030530545 3.119998762970456 0.0018085179945588 0.8081155033497385 0.033660579817095 50 Q96GM5,Q9NPF5,Q14839,Q86YP4,Q92922,Q92785,Q12824,Q9NR30,O95983,Q9UIG0,Q96T23,Q16576,Q8WUB8,Q8IXM2,Q969G3,Q12830,Q8WXI9,Q9H981,O14497,P25490,Q9NY93,Q92925,Q9NRL2,Q6ZRS2,O94776,Q86U86,Q9UEE9,Q8TAQ2,Q68CP9,P55072,Q9NRF9,Q13330 32 +Actin filament bundle 0.5374133107199466 3.0144045039191085 0.0025748425593183 0.9047532902538552 0.040209202046398 31 P21333,Q15942,Q9UHB6,Q7Z406,O75369,P29966,P35580,O00159,P35579,Q96HC4 10 +Fibrillar center 0.4566482826748281 2.9964108517444537 0.0027317810057962 0.9174865068399038 0.040209202046398 54 Q6PK04,O60832,P11387,Q9P0K7,Q15233,P17480,Q9NZM5,P68402,Q9Y5K6,P15311,Q16881,P61088,P08579,Q6P1N0,O95400,Q8WXF1,Q969X6,Q9C0J8,Q7L014,Q13428,P14373,Q14978,Q5M775 23 +U2 type spliceosomal complex 0.4297040596359989 2.9818124920822893 0.0028654744246643 0.9269830763299576 0.0408330105514668 67 Q9Y3C6,Q13573,Q9Y3B4,Q13123,Q6UX04,Q9P013,Q13435,O75400,P62314,P08579,P62304,P41223,O43290,O95232,Q9ULR0,P08621,P16383,Q96NC0,Q99459,Q9Y383,P55081,O43395,Q9BW85,Q9UQ35,P55769,Q15459 26 +I band 0.500863450631159 2.8482475432724557 0.0043960716050792 0.9820120936996416 0.0564678493497505 36 Q9Y281,Q14331,O00151,Q96HC4,O75147,O14974,Q8WX93,P12814,P62942,O75369,Q16527,Q15149,O43707,Q9NR12,P11166,O75298,O75190,Q14315,P21333 19 +Ribosome 0.442825401861241 2.839322922857827 0.0045209379614643 0.983956375508011 0.0572652141785485 153 Q6PKG0,P62913,Q15637,P83731,Q5T653,Q9P2E9,P26373,P61247,P50914,Q9BYD2,P62917,P84098,Q9NQ50,P20290,Q9BRJ2,P62841,P52815,Q02878,Q9Y3B7,Q9UHA3,P47914,P46776,P46778,P62753,Q9BYN8,Q13405,P82912,P61254,P62424,Q96A35,P62750,Q9Y291,P62273,Q9Y2R9,P62081,P62899,O95182,Q9P015,P62857,P39019,Q14197,P46779,P61353,P46777,Q5F1R6,Q8IXM3,P46782,P62263,P83881,P36578,P05387,Q96GC5,Q9BYD3,P82650,P40429,P82673,Q6P1L8,Q7Z417,P62847 59 +Ribosomal subunit 0.4268526272776963 2.795568422226867 0.0051808533753041 0.9912370294167532 0.0637242708685033 133 P62913,P83731,Q5T653,P26373,P61247,P50914,Q9BYD2,P62917,P84098,Q9NQ50,Q9BRJ2,P62841,P52815,Q02878,Q9Y3B7,P47914,P46776,P46778,P62753,Q9BYN8,Q13405,P82912,P61254,P62424,Q96A35,P62750,Q9Y291,P62273,Q9Y2R9,P62081,P62899,Q9P015,P62857,P39019,P46777,Q14197,P46779,P61353,Q8IXM3,P46782,P62263,P83881,P36578,P05387,Q96GC5,Q9BYD3,P82650,P40429,P82673,Q6P1L8,P62847 51 +Myosin complex 0.7656186542137529 2.7875786691359674 0.0053103559057086 0.9922180586239816 0.0637242708685033 10 Q92614,Q9UM54,Q7Z406,P35580,O00159,P35579,O94832 7 +Brush border 0.5115978079926664 2.778223947314364 0.0054656933633483 0.993251160020681 0.0639065685560729 31 O94832,P15311,P21333,Q9UHB6,Q7Z406,O75369,P47755,O00159,P35579,Q15149,O14745 11 +Preribosome small subunit precursor 0.6694419229368139 2.701879613942286 0.0068948721972699 0.998181787693966 0.0782455882912145 14 Q8IY81,Q96GA3,P78316,Q9NSI2,Q9ULX3,Q86U38 6 +Condensed chromosome centromeric region 0.3766792471019497 2.6936993279942385 0.0070663878484451 0.9984467773637166 0.0785920209485607 85 Q96ST3,Q8NBT2,Q9UQN3,Q9Y3E7,Q8WYP5,Q9HD42,Q9Y448,P12270,Q9HAF1,Q14141,O14974,Q96JM3,P55735,Q7Z7K6,Q9NZZ3,Q14008,Q9NQS7,Q9H444,Q9Y6D9,Q14203,Q13185,Q9H3R5,Q14807,Q15019,Q13416,Q9UEE9,O43237,Q96EE3,Q14683 29 +Cortical cytoskeleton 0.4567972858601531 2.669354987834963 0.007599708169373 0.9990484369277972 0.0818879961158261 44 Q05682,P46940,P46939,O75955,Q12802,P35241,P15311,Q9NQW6,Q9UJU6,P19022,Q13813,P67936,Q14247,P12814,O43491,Q7Z460,Q14980,Q01082,P35579,Q15334,O43707,P11166,Q9NS86,P47755 24 +Pml body 0.5104243508228464 2.668191990167624 0.0076260666263499 0.9990712100132502 0.0818879961158261 27 Q9UBW7,Q9UER7,O60934,P42345,Q01130,Q96EB6,P14373,P61956,P80723,P54132 10 +Protein acetyltransferase complex 0.5237530372157191 2.667926074511565 0.007632104901146 0.9990763498196894 0.0818879961158261 26 Q15014,Q9HAF1,Q9UPT9,Q9NPF5,P51610,Q9NPA8,O94880,Q9NRF9,Q15906 9 +Cluster of actin based cell projections 0.4800526704941105 2.642811539950316 0.0082220785861533 0.9994630107421628 0.0861900651789864 36 O14745,P15311,P21333,Q9UHB6,Q7Z406,O75369,P47755,O00159,P35579,Q15149,O94832 11 +Condensed chromosome 0.4034496265459726 2.60034952516364 0.009312885181681 0.9998031655147114 0.0943705698410346 119 Q96ST3,Q8NBT2,P46013,Q9UQN3,Q9Y3E7,Q8WYP5,O60885,P23258,Q9HD42,Q9UIG0,Q9Y448,P12270,Q9HAF1,Q14141,Q15050,O14974,Q96JM3,P55735,Q7Z7K6,Q92878,Q9NZZ3,Q9NQS7,Q14008,P16104,Q9H444,Q9Y6D9,Q14203,Q9UQE7,Q13185,Q9H3R5,Q14807,P54132,Q9Y6G9,Q15019,P26583,Q13416,Q9UEE9,P54652,O43237,O95347,Q96EE3,Q14683 42 +Condensed nuclear chromosome 0.5626213771854295 2.5933197374553005 0.009505435441367 0.9998351411976732 0.0952632650827116 22 P16104,Q9UQE7,O60885,P54652,Q15050,P54132,Q9HD42,Q92878,Q9NQS7,P23258,Q14683 11 +Cajal body 0.4834978575080204 2.5729379262024876 0.0100839291816243 0.9999032350925108 0.0990675866383013 33 Q7L014,O43395,Q9UQ35,Q9NPE3,Q14331,Q14978,Q9H814,Q9UIJ7,Q86XP3,O43290,Q01844 11 +Chromosome telomeric region 0.3653448671403358 2.5489406808338155 0.0108050677291973 0.9999502174562492 0.1011508316789488 83 O94842,P18887,P39748,P62805,Q96QC0,Q16576,P25205,O60934,Q8WXI9,Q86V81,Q9NYB0,Q92878,P16104,Q15910,Q13185,P33991,P54132,Q13769,O94776,P05455,P17544,Q13416,P09874,Q9P0M6 24 +Nuclear inclusion body 0.7650025253619503 2.5254686218880296 0.0115544099257451 0.9999750583857584 0.1060092667660623 8 P12270,P49790 2 +Microtubule plus end 0.6844755968628676 2.5165918879888096 0.0118495996910192 0.9999810057374804 0.1066037128103553 12 Q9Y448,Q14203,Q99661,Q7Z460,Q9P270,Q14980,Q15555,Q86Y91,Q14008 9 +Microtubule associated complex 0.4180096232357032 2.5144215160855694 0.0119227836695792 0.9999822463647128 0.1066037128103553 53 P46821,Q99661,Q7Z4H7,Q96CS2,Q96Q89,O15344,O95219,P33176,Q13561,Q66K74,P12270,Q02241,Q15555,Q9NQS7,Q8IVD9,Q13409,Q14203,P27816,Q14807,Q53HL2,Q9Y6G9,O95793,Q9Y496,O43237,Q86Y91,Q8NCM8 26 +Spindle pole 0.3968331487643898 2.5060730778520495 0.0122080385388883 0.9999863565346632 0.1075476258210266 66 Q96SN8,Q8WWK9,Q12834,O75449,Q13123,Q96CS2,Q96Q89,Q15398,Q9NR09,Q9UN37,O00139,P50402,Q9Y448,Q9BSJ2,Q14008,Q00839,P06748,Q96CW5,Q14203,Q9Y6D9,Q9UQE7,Q14980,Q9ULW0,Q9Y6G9,Q9Y6A5,P0DP25,Q13432,Q13257,Q08379,Q9Y3A5,P23258,Q14683 32 +Cell cortex 0.3886638172517184 2.504449737359309 0.012264202944503 0.9999870460052268 0.1075476258210266 109 Q9P0K7,P09104,Q05682,P46939,Q12802,Q14141,P15311,O75146,P09496,P19022,Q13813,Q96KP1,Q14247,O94832,Q14203,P84095,O43491,Q9UM54,P19338,Q14980,O75369,P29966,P35580,Q15019,P35579,P11166,Q9NS86,P47755,P21333,Q13112,Q02952 31 +Actin cytoskeleton 0.4146218589331662 2.4810363669958915 0.0131001006871216 0.9999940148994032 0.1106503713764222 144 Q9Y281,P04083,Q96GD0,Q9UHD8,Q9HCD5,Q05682,Q7Z406,P35611,P46940,Q96HC4,P46939,P18206,Q12802,Q07157,Q92614,Q6WCQ1,Q09666,Q9Y5K6,Q9ULV4,Q4VCS5,P15311,O14974,Q15942,P19022,Q13813,Q14247,O94832,Q9Y5S2,O43795,O14745,O00165,P07305,P59998,O43491,Q9UM54,Q96IZ0,Q99961,Q9UJZ1,Q96EY1,Q9UHB6,O75369,Q9NYL9,P29966,Q01082,P35580,Q15019,P35579,P47755,O00159,Q9NR12,P11166,Q9NS86,P78536,Q5M775,Q9UQB8,P21333 56 +Neuron projection membrane 0.7090094804211412 2.4809484150241885 0.013103333452471 0.9999940327527456 0.1106503713764222 10 Q9Y2J2,P20020,Q14168,Q01082,O00159,O94832 6 +Microtubule end 0.6286805227777307 2.4458218220093477 0.0144522403270452 0.999998285886228 0.1209214970483055 14 Q9Y448,Q14203,Q99661,Q7Z460,Q9P270,Q14980,Q15555,Q86Y91,Q14008 9 +Multivesicular body membrane 0.7246098989225987 2.436360760412052 0.0148358799659402 0.9999987982040768 0.1230029320812502 9 Q9H444,Q9UQN3,Q9Y3E7,Q9NP58,O14964,Q9HD42 6 +Mitotic spindle 0.3674923566361228 2.359020400626561 0.0183232484306044 0.9999999526546351 0.1453113266844453 74 Q9H0H5,Q13123,Q96CS2,Q9Y448,P12270,Q02241,Q14247,Q14203,Q9Y6D9,Q9UQE7,P27816,Q14980,Q14807,Q9ULW0,Q9Y6A5,O60610,Q15051,O00311,Q9HC35,Q08379,P23258,Q14683 22 +Adherens junction 0.4135156745353685 2.3364110272839564 0.0194698297779898 0.9999999836921554 0.1528399469978802 48 P04083,P35611,P35221,O00151,P26038,Q96HC4,O00192,P18206,O75955,Q07157,P15311,Q15942,P19022,Q9Y490,Q9NYL9,P35579,Q9NR12,Q9UDY2,O96013,P55196,Q13112,Q5EBL8,Q9UQB8,Q8N3R9 24 +Centriole 0.461612162362653 2.331743811233643 0.0197141725451353 0.9999999870077568 0.1528399469978802 32 Q13464,Q15051,Q9UPN4,Q9Y366,O15078 5 +Heterochromatin 0.4491210489096054 2.330583279214462 0.0197753440194625 0.9999999877265252 0.1528399469978802 36 P45973,P10412,Q9NRZ9,Q15910,Q13416,P17096,Q9NZM5,P26358,P51608,Q99496,Q96EB6,Q13185,P22314,Q9NQS7 14 +Precatalytic spliceosome 0.436949077120506 2.3013908727507206 0.0213695473632631 0.9999999972185072 0.1610663404569915 39 Q13435,P55081,O43395,P55769,Q13123,P62314,P08579,O43290,Q15459,Q6UX04 10 +Nuclear pore nuclear basket 0.6737780792625361 2.2848576270585124 0.022321177319551 0.9999999988546404 0.165503363540086 10 P12270,Q9NPA8,Q9Y6D9,P49790 4 +Transcription repressor complex 0.5786872063295884 2.2648641931499824 0.0235210146831441 0.9999999996262632 0.1729932692824796 15 Q96ST3,P07305,Q01664,Q9UHI6,P51858 5 +Box c d rnp complex 0.8103867029853196 2.248860416640313 0.0245213780739557 0.9999999998532448 0.1774880698686318 6 O43818,Q14978 2 +Sm like protein family complex 0.3952361144521241 2.23206283890616 0.0256108100577072 0.9999999999470336 0.1810624711056513 53 Q9Y3B4,P09012,Q13435,O75400,P62314,P08579,P62304,O43290,O95232,Q7L2J0,O95400,P08621,Q9Y383,O43395,Q9UHI6,P55769,Q9BUQ8,O94992,Q15459 19 +Ciliary transition zone 0.6482777777152148 2.2176634128748143 0.0265777906579955 0.999999999978584 0.1842555305618138 11 Q9UPN4,Q15051,Q9Y366,O15078 4 +Neuron to neuron synapse 0.3672272024019989 2.211294713358704 0.0270154352094897 0.9999999999857888 0.1842555305618138 70 Q9BY67,P46821,Q8IZP0,P35611,Q96HC4,P40818,Q13177,P50914,P62917,O75146,Q9UJU6,P25685,P19022,Q02878,P50570,Q9Y639,P62269,P62277,P11274,O43815,Q01082,P39019,P62263,Q9UQ16,O43164,Q14168,P51991,Q9UQB8,Q06787,Q96PE3 30 +H4 h2a histone acetyltransferase complex 0.682741814327722 2.2110195614759 0.0270344824828905 0.9999999999860404 0.1842555305618138 9 Q9NPF5,Q15014,Q15906 3 +Cleavage furrow 0.5135409554695298 2.2054794171930117 0.0274204705768918 0.999999999990279 0.1842555305618138 22 Q16513,Q9H0H5,Q14141,Q9UHB6,P35580,Q15019,P35579 7 +Iswi type complex 0.6579801115410678 2.1956316680717025 0.0281183176724435 0.9999999999949484 0.1842555305618138 10 Q96T23,Q16576,Q12830,Q9NRL2,Q9NRF9,Q9UIG0 6 +Pronucleus 0.7980741273572074 2.1927061555691365 0.0283285569627524 0.9999999999958532 0.1842555305618138 6 Q15910 1 +Cell cell junction 0.3787887213561817 2.1803091662648946 0.0292345520704502 0.9999999999982288 0.1842555305618138 121 Q9BY67,P04083,Q96GD0,Q9Y2J2,Q16513,P35611,P46940,Q92974,P11802,Q96HC4,Q9UNF0,P18206,O75147,Q07157,Q09666,Q9Y5K6,Q4VCS5,P15311,Q15942,P19022,Q9Y5S2,Q9Y490,O43815,Q13308,Q86VI3,Q9NYL9,P05026,P58107,P35579,Q5EBL8,Q9NR12,P11166,Q9UDY2,O96013,Q16625,P55196,Q13112,Q8N3R9,Q14168,P78536,P22314,Q9UQB8,P21333,Q9H307 44 +Nuclear chromosome 0.3589671273570192 2.180047843321115 0.0292539153114839 0.9999999999982608 0.1842555305618138 99 Q96ST3,P84243,P18754,O60885,P11387,Q9NPF5,Q13123,Q9UNS1,Q12824,Q9HD42,Q9UIG0,P62805,P49642,P25205,Q969G3,Q9BYG3,Q15050,Q9H6R4,Q9H981,Q9NYB0,Q92878,Q9NQS7,Q00839,P25490,P16104,Q9UQE7,Q9BRX5,Q9NRL2,P33991,P54132,Q6ZRS2,Q13416,Q86U86,Q9UEE9,P54652,O95347,Q9P0M6,O75367,O75717,Q9NRF9,P23258,Q14683 42 +Cortical actin cytoskeleton 0.4377919059839014 2.123540422311351 0.0337085919595807 0.9999999999999738 0.2001710841742949 33 Q12802,P35241,P11166,O43491,Q9NS86,Q9UJU6,Q9NQW6,Q05682,P19022,Q15334,P46940,Q13813,Q01082,P35579,Q14247,P46939,P12814,O75955 18 +Nbaf complex 0.6872282202489806 2.1224398468010133 0.0338008190382033 0.999999999999976 0.2001710841742949 8 Q96GM5,Q8TAQ2,Q969G3,Q92922,Q92785,Q12824 6 +Filamentous actin 0.6426608863086993 2.1083582510569028 0.0350000128018714 0.9999999999999922 0.2046154594570948 10 O00159,Q9Y5K6,Q96HC4,Q5M775 4 +Myosin filament 0.9062327633756156 2.0972018876431298 0.0359757074782634 0.9999999999999968 0.208979905860995 4 Q13049,P35579,Q7Z406 3 +T tubule 0.6784065312491142 2.07566796640018 0.0379246706116354 0.9999999999999996 0.2175301861497578 8 Q09666,P05026 2 +Immunological synapse 0.5698626958759667 2.0643635601652943 0.0389832587655716 0.9999999999999998 0.220651436629432 14 Q13740,P15311,Q9UJZ1,P20020,P35579 5 +U1 snrnp 0.6212158871074861 2.058774733098128 0.0395158232145191 1.0 0.220651436629432 11 O95232,O75400,P08621,P62314,P08579,Q9Y383,P09012 7 +Spliceosomal snrnp complex 0.4038688287402407 2.0460204464017493 0.0407543590617747 1.0 0.2213256669809098 43 Q13435,O95232,O95400,O75400,P08621,O43395,Q9Y383,Q9Y3B4,P55769,P62314,Q9BUQ8,P08579,P09012,P62304,O43290,Q15459 16 +Prespliceosome 0.6311594062009035 2.04235916164127 0.0411159175557673 1.0 0.2218799811293482 10 O95232,Q9Y383,O75400,Q15459 4 +Cell division site 0.4381260877448522 2.0359539833597395 0.0417549762676827 1.0 0.2240031668007452 29 Q16513,Q96GD0,Q9H0H5,Q14141,Q9UHB6,P35580,Q15019,P35579 8 +Costamere 0.7622014719381 2.0272799882554597 0.0426337868859612 1.0 0.2241238482813966 6 Q09666,Q14315,P18206 3 +Chromosome centromeric region 0.3597677988866354 2.026042095571577 0.0427604710536875 1.0 0.2241238482813966 110 Q96ST3,P45973,Q8NBT2,Q9UQN3,Q9Y3E7,Q8WYP5,Q9HD42,P62805,Q9UER7,Q9Y448,P12270,Q9HAF1,Q14141,O14974,Q96JM3,P55735,Q7Z7K6,Q9NZZ3,Q14008,Q9NQS7,Q9H444,Q9Y6D9,Q15910,Q14203,Q9UQE7,P26358,Q13185,Q9H3R5,Q14807,Q9Y6G9,Q15019,Q13416,Q9UEE9,O43237,Q96EE3,Q14683 36 +Histone deacetylase complex 0.4378687126469289 2.015670850287724 0.0438344056818382 1.0 0.2258586326657429 28 Q96ST3,P45973,Q16576,O75446,Q9UEE9,Q9NPF5,Q8WXI9,Q86YP4,Q7LBC6,Q6ZRS2,O94776 11 +Mitochondrial large ribosomal subunit 0.4146991621157602 2.006508489974496 0.0448020238609676 1.0 0.2281665502595236 37 Q8N5N7,Q5T653,Q9BYD2,Q9NQ50,Q9BRJ2,P52815,Q9Y3B7,Q567V2,Q13405,Q96A35,Q9NRX2,Q8N983,Q9BYD1,Q9P015,Q14197,Q8IXM3,Q96GC5,Q9BYD3,Q6P1L8,Q13084 20 +Dendrite cytoplasm 0.6120362358290915 2.004347286892787 0.045032871761748 1.0 0.2281665502595236 11 P23246,P33176,Q8N2K0,O75146,Q9UQB8,Q6PJT7,Q00839 7 +Ruffle 0.3654249550262328 2.000516617491983 0.0454445073531855 1.0 0.2289800591497523 63 O14745,Q13464,Q9Y448,Q9NR12,Q96GD0,Q9UM54,Q4VCS5,Q9Y5K6,O75146,P15311,Q9UHB6,P78536,O00159,Q92974,P35579,Q14247,Q9UNF0,Q9Y490 18 +U2 type catalytic step 2 spliceosome 0.4589933113736233 1.9965035236165205 0.0458791426008602 1.0 0.2298998794065084 25 Q9P013,Q9Y3C6,P41223,Q9UQ35,Q13573,Q99459,P62314,P08579,P62304 9 +Nuclear pore 0.3742600373167706 1.9883301922695569 0.0467751837200738 1.0 0.2308033891866483 55 Q9H444,P12270,Q9Y6D9,Q9UQN3,Q8TD16,Q9NPA8,P49790,O00159,P35658,Q8NFH5 10 +Rna polymerase ii transcription regulator complex 0.4035743727697707 1.988314480588852 0.0467769202697854 1.0 0.2308033891866483 41 Q9NPJ6,P13984,Q14839,Q15648,Q15233,P23193,Q71SY5,Q9H1I8,P29083,O75528,Q9NVC6,P35269,Q13503,P23246,Q13263,P17096,Q13185,Q9H2P0,P32780,P17544,P18074,Q15650 22 +Sex chromosome 0.5753786846016175 1.9737852762357069 0.0484061637383566 1.0 0.2347855706364263 13 P16104,P84243,Q99496,Q92922,Q9P0M6,O75367,Q00839 7 +Paraspeckles 0.7499874248674743 1.970353380369115 0.0487978845871071 1.0 0.2347855706364263 6 Q8WXF1,P52272,Q15233 3 +H4 histone acetyltransferase complex 0.5930938958665135 1.9693434874138496 0.0489136605492555 1.0 0.2347855706364263 12 Q9NPF5,Q15014,Q9HAF1,Q15906 4 +Escrt complex 0.5728505597870837 1.9576350459421492 0.050272851972656 1.0 0.2387960468701163 13 Q9H444,O14964,Q9UQN3,Q9Y3E7 4 +Granular component 0.8687818767007671 1.9444182206758147 0.0518450383877437 1.0 0.2427731114844336 4 O75683 1 +Supramolecular polymer 0.4162000713005028 1.9440986845550376 0.051883551875659 1.0 0.2427731114844336 244 Q05682,Q7Z406,Q96CS2,Q6SZW1,Q9BRK0,Q13049,Q92974,Q09666,O14974,Q9BSJ2,P48681,Q9NQS7,Q13409,Q9P270,P27816,Q14980,Q96EY1,Q01082,Q15149,Q9NR12,O43237,Q14315,Q5M775,Q9UQB8,O00159,Q9H307,Q96ED9,Q9Y281,P04083,Q9UQN3,Q9HD42,Q96HC4,O75147,Q02241,Q9Y5K6,Q86VS8,Q9NZZ3,O43795,Q9H444,P49257,Q14807,Q9NYL9,Q9ULW0,Q9Y6G9,P35579,P55081,Q9Y496,Q8NCM8,P23258,P46821,P07197,Q9Y3E7,Q9H0H5,Q14331,Q9UHD8,O75347,Q7Z4H7,P46940,O15344,P50402,P18206,Q9Y448,Q9ULV4,Q4VCS5,P16949,Q15555,P62942,Q9UM54,Q96IZ0,O75369,Q16527,P35580,Q5VU43,P11166,O75298,O75190,Q86Y91,Q08379,P21333,Q8WWK9,Q99661,Q9BVA1,O00151,Q03252,P33176,Q13561,Q66K74,Q9UJU6,P15311,P06733,P50570,Q14008,P67936,Q00839,Q14247,Q96CW5,Q14203,Q7Z460,P02545,P58107,P0DP25,Q9HC35 102 +Mediator complex 0.5703195116965447 1.941444883262641 0.0522043386668009 1.0 0.2429099840006248 13 Q9NPJ6,Q71SY5,Q9Y2W1,Q9NVC6,Q15648,P11802,Q9NYF8 7 +Amphisome 0.6946748231158622 1.9208471621582 0.0547509787022697 1.0 0.246165084237226 7 Q9HD42,Q9H444,Q9UQN3,Q9Y3E7 4 +Amphisome membrane 0.6946748231158622 1.9208471621582 0.0547509787022697 1.0 0.246165084237226 7 Q9HD42,Q9H444,Q9UQN3,Q9Y3E7 4 +Small subunit processome 0.4151116232911735 1.9205277386508623 0.0547912728543686 1.0 0.246165084237226 34 O00566,Q9BSC4,P55769,O43818,P78316,P62081,Q9NV06,Q9BVJ6 8 +Chromatin silencing complex 0.6464423481864638 1.9044924535961625 0.0568460785609623 1.0 0.251668075959212 8 Q9UIF9,Q15910,Q96EB6,Q13185,P25490 5 +Intermediate filament 0.4919308667159078 1.8972302299903196 0.0577975586991881 1.0 0.253887339811882 20 P07197,O75298,P48681,P02545,P58107,Q03252,Q15149 7 +Swi snf complex 0.5939601251158643 1.8964230211653343 0.0579041301325344 1.0 0.253887339811882 11 Q96GM5,Q86U86,Q92925,Q8TAQ2,Q969G3,Q92922,Q12824,O14497 8 +Organellar ribosome 0.366010986427607 1.893333414677449 0.0583135441693385 1.0 0.2544591018298409 56 Q5T653,Q9BYD2,Q9NQ50,Q9BRJ2,P52815,Q9Y3B7,Q9BYN8,Q13405,P82912,Q96A35,Q9Y291,Q9Y2R9,Q9P015,O95182,Q14197,Q8IXM3,Q96GC5,Q9BYD3,P82650,P82673,Q6P1L8 21 +Ciliary basal body 0.425667321025305 1.8838024618644944 0.0595917004405324 1.0 0.2578409144933309 27 Q9UPN4,Q13526,Q9Y366,Q9BV73,O15078 5 +Cell cell contact zone 0.436189573309287 1.8833423804598353 0.0596539835066807 1.0 0.2578409144933309 26 P11166,Q9UDY2,Q09666,P55196,P19022,P05026,P18206 7 +Multivesicular body 0.520925496683115 1.866779593312656 0.0619323733674193 1.0 0.2618365147735704 15 Q9NP79,Q9H444,Q9UQN3,Q9Y3E7,Q9NP58,O14964,Q9HD42 7 +Laminin complex 0.943495038588762 1.8661962654471729 0.0620139113937403 1.0 0.2618365147735704 2 P07942 1 +Dynein complex 0.5388958187113737 1.8582062162872488 0.0631397355980163 1.0 0.2650975167034693 14 Q13409,Q13561,Q14203,P12270,O43237,Q9Y6G9,O95219,Q8NCM8 8 +Myosin ii complex 0.8474749343462392 1.8566033417561325 0.0633676081593819 1.0 0.2650975167034693 4 P35579,Q7Z406 2 +Cell projection membrane 0.3342958621285795 1.8542526074341792 0.0637030289251994 1.0 0.2652016228269866 74 Q96GD0,Q9Y2J2,P55011,Q92974,P46939,Q9UNF0,O75146,P15311,O14745,O94832,Q9Y490,Q9UM54,Q9H4M9,O95721,Q9UHB6,Q01082,Q15019,Q14168,P78536,O00159 20 +Atpase dependent transmembrane transport complex 0.7244386541544078 1.850337875241951 0.0642648669350482 1.0 0.2652016228269866 6 O14678,P05026 2 +Actin filament 0.3939068775936453 1.8172070628415635 0.069185413926528 1.0 0.2773970028623873 38 P04083,Q9NR12,Q9UM54,Q96IZ0,Q4VCS5,Q9Y5K6,P15311,Q9UJU6,Q96EY1,P46940,O00151,Q5M775,O00159,Q96HC4,Q14247,O43795 16 +Microtubule cytoskeleton 0.3442609408010025 1.8161377074969176 0.0693492507155968 1.0 0.2773970028623873 396 Q3KQU3,Q9UPN4,Q12834,Q8TD16,O60271,Q9NZM3,Q96CS2,Q9BRK0,Q6SZW1,Q92974,Q9UN37,O15078,Q7Z6E9,P25205,O14974,Q9H981,Q9BSJ2,Q9UIJ7,P43487,Q9NQS7,P06748,Q13409,P0DMV9,Q9Y6D9,Q9P270,P27816,Q14980,Q9UNZ2,O95721,P62081,Q96CT7,Q15051,Q13432,Q9Y366,O43237,P53990,Q5M775,Q9UQB8,Q9BTC0,Q96ED9,Q13464,Q9UQN3,P51608,P13984,Q9Y237,Q9HD42,O75147,P12270,Q9Y5K6,Q02241,Q14141,Q96JM3,Q9BV73,P31689,Q9H814,Q86VS8,Q9NZZ3,Q9H444,Q14807,Q9ULW0,Q9Y6G9,P35579,O60610,Q14498,P55081,O95793,Q9Y496,O75116,Q8NCM8,P23258,P46821,Q9Y3E7,Q9H0H5,Q9UHD8,O75347,Q7Z4H7,Q92785,P46940,Q9H7N4,O15344,Q9Y448,P16949,O75592,P09496,Q13813,P16104,Q13185,P29966,Q15019,Q5VU43,O00311,P54652,Q08379,Q14683,Q8WWK9,Q16513,Q13123,Q9NV06,Q15398,P33176,Q13526,P15311,Q7Z7K6,Q6P1N0,Q14008,Q14247,Q14203,Q9UQE7,Q9Y6A5,Q13416,Q9HC35,Q9BZI7 112 +Prp19 complex 0.5770732814195412 1.794753464098993 0.0726929881685523 1.0 0.2869956935485701 11 Q9P013,Q9ULR0,Q8WYA6,Q99459,P11142 5 +Npbaf complex 0.6038500426894813 1.7727403527016807 0.0762717412147833 1.0 0.2982963888436172 9 Q96GM5,Q8WUB8,Q8TAQ2,Q969G3,Q92922,Q12824 6 +Photoreceptor connecting cilium 0.6214996116361313 1.769181126235367 0.0768636528270285 1.0 0.2982963888436172 8 Q15051,Q9Y366,O15078 3 +Site of double strand break 0.4116430441499835 1.7633181435029273 0.0778468469184505 1.0 0.3008318830068937 28 P59998,P16104,P09874,O60934,P02545,Q9UNS1,Q92878,Q96T60 8 +Cell leading edge 0.358060029901349 1.7531816664387394 0.0795708289422814 1.0 0.3023691499806693 128 Q13464,Q8IZP0,Q96GD0,Q9Y2J2,Q16513,P46940,Q9H7N4,Q92974,Q9NZI8,Q9UNF0,Q9Y448,Q9Y5K6,Q9ULV4,Q14444,Q4VCS5,O75146,P15311,P19022,Q14247,Q9Y5S2,O94832,Q9Y490,O14745,P51809,O00165,Q12846,Q9UM54,Q9UHB6,Q9Y6W5,Q01082,P35580,P35579,O00159,O60610,P11940,Q9NR12,Q16625,Q2M2I8,Q9H2G2,P20020,Q14168,P78536,Q9UQB8,P23258 44 +Pericentric heterochromatin 0.5566705974753461 1.7436086788743064 0.0812273489125838 1.0 0.3070348461286986 12 P45973,Q15910,P26358,Q13185,Q9NQS7 5 +Sarcolemma 0.4094758501337027 1.7287657960686484 0.0838510201017528 1.0 0.3108623184260105 27 P11166,Q09666,P19022,Q14315,P05026,P46939,P18206 7 +Euchromatin 0.427591493458508 1.71488538148718 0.0863662433432408 1.0 0.3176048948751437 25 P16403,O75475,P07305,P16402,Q99496,Q13185 6 +Brca1 c complex 0.8113032998915604 1.7061861241155647 0.08797343139745 1.0 0.3198883133267697 4 Q92878 1 +Kinesin complex 0.4980699531666473 1.7058316037587866 0.0880394371107666 1.0 0.3198883133267697 15 Q07866,Q99661,Q02241,Q9Y496,Q14807,Q86Y91,Q9H0B6,Q96Q89,O00139,P33176 10 +Escrt iii complex 0.6898344081859882 1.6859152599609986 0.091812122279915 1.0 0.3283633549775787 6 Q9H444,Q9UQN3,Q9Y3E7 3 +Septin cytoskeleton 0.6891072653440257 1.6824392516650029 0.0924836954199674 1.0 0.3287553955224314 6 Q15019,Q9UHD8,Q14141 3 +Site of dna damage 0.3758173400624924 1.6779120431584291 0.0933642711268176 1.0 0.3300318421227043 41 P59998,P16104,O60934,Q14241,Q13185,P02545,Q9UNS1,Q92878,Q96T60 9 +Spectrin 0.788855192164542 1.6120952937971724 0.1069412046953941 1.0 0.365669348074052 4 Q13813,O43491 2 +Stereocilium bundle 0.5912773751265116 1.6034602972387182 0.1088330678973421 1.0 0.3689805127225875 8 O00159 1 +Cytosolic small ribosomal subunit 0.3879944491115225 1.5971255984503154 0.1102377131240652 1.0 0.371064185052118 32 P46782,P62263,P82912,P62841,P62273,P62081,P62857,P39019,P61247,P62753 10 +Germ cell nucleus 0.6682606530013997 1.5824613328991888 0.1135442927872023 1.0 0.3779284489851406 6 P16104,P29966 2 +Saga complex 0.6676404359085708 1.5794778739699944 0.1142264876781438 1.0 0.3782981231417139 6 Q9NPA8,Q9UPT9 2 +Lateral element 0.7762598815611045 1.5590936068661805 0.1189742265857729 1.0 0.388904998731989 4 Q9UQE7,Q9NQS7 2 +Chromatin 0.3920959107187779 1.554722703576623 0.1200121250581431 1.0 0.3889347162287765 226 Q96ST3,Q9UIF9,P84243,Q8WYP5,P18754,Q15059,O75150,Q14839,P38159,Q96EK4,Q12824,Q9NZM5,Q9UBU8,Q9H981,O14497,Q9NQS7,P25490,P26367,P42771,P23246,Q13263,Q92925,Q5VTR2,Q13111,Q99733,Q96L73,O75569,Q9UEE9,Q5SSJ5,Q16630,P05204,Q68CP9,P53990,Q9NRF9,Q13330,Q15906,Q15014,O15047,O60885,P51608,O94842,Q86YP4,Q92922,P18887,Q9NR30,Q9UIG0,P62805,Q7Z3K3,Q16576,P16402,Q8WXI9,P05114,Q15910,P17096,P26358,Q96EB6,Q99640,Q14807,Q9NRL2,Q7LBC6,Q92522,O94776,P17544,P26583,P22314,P45973,Q9NRZ9,Q8NC56,Q9NPF5,O75179,Q92785,P11802,O95983,Q9HAF1,Q8IXM2,Q969G3,Q12830,P41223,P16403,P16104,P10412,P07305,Q9NY93,Q96IZ0,Q9P1Z2,Q13185,Q9H2P0,Q6ZRS2,Q96SB4,Q9BUQ8,O95347,Q96GM5,Q9H0U9,Q9Y5B9,O95747,Q9UNS1,Q96T23,Q96QC0,Q8WUB8,P80723,Q01664,Q9UQE7,Q99496,O75475,P42167,Q13416,Q86U86,Q8N7H5,Q8TAQ2,Q9H1E3,Q9P0M6,P25440,O75367,Q13112 114 +Leading edge membrane 0.351497295858399 1.5536718615178828 0.1202627083075822 1.0 0.3889347162287765 47 Q96GD0,Q9Y2J2,O94832,Q9UM54,Q9ULV4,O75146,P15311,O60610,P20020,Q14168,P78536,Q01082,O00159,Q92974,Q9UNF0,Q9Y490 16 +Sperm annulus 0.9034430263051022 1.5405524974760103 0.1234257366444913 1.0 0.3977536106705868 3 Q14141 1 +Unconventional myosin complex 0.7684656276724089 1.5262304780541505 0.1269524756217299 1.0 0.4020161728021448 4 O00159 1 +Saga type complex 0.542963749352287 1.524408907646989 0.1274065963196524 1.0 0.4020581863097683 10 Q9NPA8,Q9NRF9,Q9UPT9 3 +Pcg protein complex 0.5296328082238032 1.505493166851131 0.132197332322564 1.0 0.411481116307776 11 Q99496,Q15910,Q16576,Q14157 4 +9plus0 non motile cilium 0.4648282603045143 1.5009648299741047 0.1333646584235794 1.0 0.4137026138853893 16 Q9BV73,Q15051,Q9Y366,O15078 4 +Nurd complex 0.5266131413252201 1.4869411479890768 0.1370303552453053 1.0 0.4151187736659742 11 Q86YP4,Q16576 2 +Centrosome 0.3781331640454278 1.4834834728325164 0.1379460043031988 1.0 0.4151187736659742 191 Q96SN8,Q9UPN4,Q12834,Q8TD16,O60271,Q14839,Q9NZM3,Q71F23,Q96CS2,Q96Q89,Q9UN37,O00139,O15078,Q7Z6E9,P25205,O14974,Q9H981,Q9BSJ2,Q9UIJ7,P43487,P06748,Q13409,P0DMV9,Q9Y6D9,Q9P270,Q14980,O95721,P62081,Q15051,Q13432,Q9Y366,O43237,P53990,Q96ED9,P51608,O75147,Q02241,Q9Y5K6,Q9BV73,Q9H814,Q86VS8,Q9Y6G9,Q14498,P55081,Q9Y496,O75116,P23258,Q7Z4H7,Q92785,P50402,Q9Y448,Q8WYA6,P16104,Q96CN5,Q9Y5K8,P29966,Q5VU43,Q8WXW3,P36957,Q8WWK9,Q99661,Q16513,Q9NV06,Q15398,P33176,Q13561,P50570,Q14008,Q00839,Q96CW5,Q14203,Q7Z460,Q9Y6A5,P0DP25,Q13416,Q9BZI7,Q15154,Q15650 78 +Intermediate filament cytoskeleton 0.3725830103251444 1.480185921117045 0.1388236366111668 1.0 0.4151187736659742 34 P07197,Q16513,O75298,Q9UNZ2,P48681,P02545,P58107,Q03252,Q15149 9 +A band 0.6465659319737346 1.4778396779977032 0.1394506953034604 1.0 0.4151187736659742 6 O75147,Q01082,O14974 3 +Brush border membrane 0.5513811354298339 1.4731537648655433 0.1407095788311014 1.0 0.4151187736659742 9 Q9UHB6 1 +Prefoldin complex 0.6454771268794457 1.472576187004748 0.1408653497255039 1.0 0.4151187736659742 6 Q9NUG6,O15212 2 +Pericentriolar material 0.6421971060132884 1.4567136225197796 0.1451954478496253 1.0 0.417054173150688 6 Q86VS8,Q96SN8,Q15154,P23258 4 +Microvillus membrane 0.64197535397186 1.4556408722153775 0.1454919230639721 1.0 0.417054173150688 6 O14745,P26038,Q01650,P15311 4 +Cell trailing edge 0.641921599810182 1.455380824287272 0.145563862074836 1.0 0.417054173150688 6 P35579,P26038,P15311 3 +Spindle 0.36533756241083 1.4550975342363464 0.1456422617202348 1.0 0.417054173150688 167 Q3KQU3,Q8WWK9,Q9UQN3,Q12834,Q9Y3E7,Q9H0H5,Q9Y237,Q13123,Q7Z4H7,Q96CS2,Q9HD42,Q92974,O15344,Q15398,Q9UN37,P50402,Q9Y448,P12270,Q02241,Q14141,Q96JM3,P09496,Q9BSJ2,Q7Z7K6,Q9NZZ3,Q14008,Q9NQS7,Q14247,P06748,Q9H444,Q9Y6D9,Q14203,Q9UQE7,P27816,Q14980,Q13185,Q14807,Q9ULW0,Q9Y6G9,Q15019,P35579,Q9Y6A5,O60610,Q15051,Q13432,O00311,Q9Y496,P54652,Q9HC35,Q08379,Q9BTC0,P23258,Q14683 53 +Intercellular bridge 0.3807274997077041 1.4510610145541212 0.146762871035621 1.0 0.417054173150688 27 Q15051,Q9UPN4,O00311,Q9H7N4,O75937,Q15019 6 +Meiotic spindle 0.8783692496852109 1.4430594079798504 0.1490037367740886 1.0 0.4207164332444855 3 Q9NQS7 1 +Neuron projection terminus 0.4514318256633385 1.4384169023831843 0.1503157996554875 1.0 0.421424632098675 17 Q2M2I8,O75150,Q14141,O75494,Q05682,Q9UQB8 6 +Non motile cilium 0.4264487794879565 1.429774083158767 0.1527818697372465 1.0 0.4250089132868575 21 P46821,Q15051,Q9UHD8,Q9NX58,Q9Y366,Q9BV73,Q15555,P23258,Q15019,O15078 10 +Cytoplasmic dynein complex 0.5063865610487361 1.42678582973491 0.1536416368675277 1.0 0.4259002213470678 12 Q13409,P12270,O43237,Q9Y6G9,O95219,Q8NCM8 6 +Mitotic spindle pole 0.4291152805426089 1.399165256231852 0.1617634326946633 1.0 0.4411916874242037 20 Q13123,Q9Y6D9,Q14980,Q14683 4 +Meiotic cohesin complex 0.7357689395509144 1.387965164563268 0.1651476529813926 1.0 0.4482579152352087 4 Q14683 1 +U2 snrnp 0.4530893288742591 1.3852772432606637 0.1659677094216478 1.0 0.4491470355861805 15 P08579,Q13435,Q15459 3 +Mrna cleavage factor complex 0.4689434126101989 1.3824497456763485 0.1668336508054715 1.0 0.4501547027650592 14 Q05048,Q8N684,Q9P2I0,P33240,Q6UN15,O94992,Q9C0J8 7 +Synaptonemal structure 0.5336608881143929 1.3710846322464083 0.1703485749985116 1.0 0.4553036536939263 9 P54652,Q9NQS7,Q9UQE7 3 +Terminal bouton 0.5857410280181721 1.3640362647694182 0.1725561523318841 1.0 0.456714159121829 7 Q05682 1 +Seh1 associated complex 0.8244211686879812 1.3617685431697817 0.173270941947536 1.0 0.456714159121829 2 P55735 1 +Gator2 complex 0.8244211686879812 1.3617685431697817 0.173270941947536 1.0 0.456714159121829 2 P55735 1 +Basement membrane 0.6220735858819999 1.3592237449144202 0.1740756991763792 1.0 0.4575130767978612 6 P07942 1 +Spliceosomal tri snrnp complex 0.394539347736571 1.342495223038565 0.1794354782215363 1.0 0.462274452367348 24 O95400,O43395,P55769,P62314,Q9BUQ8 5 +Mrna cleavage and polyadenylation specificity factor complex 0.5081878978671412 1.3162249936394723 0.188098537227471 1.0 0.4791783965124402 10 Q8N684,Q9P2I0,P33240,Q9C0J8,Q6UN15 5 +Spindle midzone 0.4057030474650731 1.3138294427451156 0.1889036070674234 1.0 0.479888829096073 22 Q13432,Q9H0H5,Q14980,Q15555,Q86Y91,Q9NQS7,Q53HL2,Q7Z7K6,Q14247,Q00839 10 +Basal part of cell 0.316481674687143 1.2951456081661792 0.1952700040720132 1.0 0.4889191881834053 61 Q15758,Q9BY67,P04083,Q07157,Q9NWH9,P11166,P55011,P15311,P04920,P19022,P20020,Q14168,P05026,P58107,O00159,O94832,Q5EBL8 17 +Podosome 0.4948214950275853 1.2911324634734067 0.1966577488423164 1.0 0.4898164995071903 11 Q07157,Q99961,Q9UJU6,Q14247,P67936,P18206 6 +Axolemma 0.835401157981802 1.2758706892759482 0.2020012338616585 1.0 0.4992550820645871 3 Q9Y2J2,O94832 2 +Photoreceptor inner segment 0.5275958662927821 1.250241254484309 0.2112114307999912 1.0 0.5140694622587267 8 Q9BV73,P11166 2 +Neuron spine 0.3406598849171434 1.2497873289810044 0.2113772459945422 1.0 0.5140694622587267 39 P46821,Q12846,P11274,O43815,O75146,Q15075,P25685,P20020,Q14168,Q9UQB8,Q9NZI8,Q14247,P40818 13 +Spindle pole centrosome 0.5089245337080277 1.2283903267233414 0.2193004774000875 1.0 0.525115872723598 9 P06748,Q15398,Q14980 3 +Endocytic vesicle lumen 0.5949268484200505 1.2274898260233085 0.2196385434163947 1.0 0.525115872723598 6 P07900,O14964,Q9Y4L1 3 +Rdna heterochromatin 0.6976513293408281 1.2264485452530662 0.2200299272394912 1.0 0.525115872723598 4 Q9NZM5,Q96EB6 2 +Intercalated disc 0.4224752197066768 1.2225275804234 0.2215081805759666 1.0 0.525115872723598 17 P19022,P18206,P05026 3 +Inclusion body 0.3538950274697178 1.2217214345766323 0.2218129876957064 1.0 0.525115872723598 30 P13807,P07197,P0DMV9,P12270,O60934,P49790,Q9UMX0,P35573 8 +H3 histone acetyltransferase complex 0.8202412562708696 1.2170058207841257 0.2236020012062085 1.0 0.525115872723598 3 Q9HAF1 1 +Midbody 0.2997917485309729 1.2154663886237809 0.224188260670755 1.0 0.525115872723598 99 Q9UQN3,Q96GD0,Q9Y3E7,Q16513,Q9H0H5,O95319,Q9HD42,Q9UN37,P40818,Q13526,Q02241,Q14141,Q96JM3,Q96KP1,Q7Z7K6,Q9NZZ3,Q9NQS7,Q9H444,O95785,P35580,Q15019,Q96CT7,Q15424,P11166,Q9HC35,P53990 26 +Transcription export complex 0.5062837501789546 1.2131659087453834 0.2250663953020268 1.0 0.525115872723598 9 Q13769,P82979,Q86V81 3 +Tight junction 0.3551269958824447 1.2119233652005517 0.2255417171896967 1.0 0.525115872723598 28 Q07157,O43815,Q9UDY2,Q16625,Q4VCS5,Q8N3R9,P58107,Q92974,Q13112 9 +Microvillus 0.3932845432364956 1.2098333365061775 0.2263428515038992 1.0 0.525115872723598 22 O94832,Q9UM54,P36543,Q01650,P15311,O00159,P26038,O14745,O43795 9 +Small ribosomal subunit 0.315783834036612 1.2094633024996777 0.2264849014931225 1.0 0.525115872723598 50 Q9BYN8,P46782,P62263,P82912,Q9Y291,P62841,P62273,Q9Y2R9,P62081,P82650,P62857,P82673,P39019,P61247,P62753 15 +Extrinsic component of plasma membrane 0.3341610288591812 1.2087405282325072 0.2267625460971429 1.0 0.525115872723598 41 P60903,P04083,Q9H0H5,Q14980,Q2M2I8,Q15075,Q9UJZ1,Q96EY1,O00291,P19022,P46940,A0FGR8,P40818 13 +Preribosome large subunit precursor 0.3914979797850778 1.194903545800753 0.2321247173740435 1.0 0.5334767621051248 22 Q9H9Y2,Q8IY81,Q15050,Q99848,Q969S3,Q9Y3B9 6 +90s preribosome 0.3521772475898364 1.1931487273941657 0.2328111308309646 1.0 0.5334767621051248 29 Q14137,O00566,Q969X6,Q9H6R4,P78316,Q9NSI2,Q14692,Q8N9T8,Q8NEF9,Q86U38 10 +Mcm complex 0.5862873484644919 1.1855887615813745 0.2357847425991412 1.0 0.5355218113811298 6 P33991 1 +Chromosomal region 0.3551477058192875 1.1834279835225885 0.2366395723537229 1.0 0.5355218113811298 180 Q96ST3,P45973,Q8NBT2,Q9UQN3,Q9Y3E7,Q8WYP5,O94842,P18887,Q9HD42,P39748,P62805,Q9UER7,Q9Y448,P12270,Q16576,Q9HAF1,P25205,O60934,Q96QC0,Q14141,Q8WXI9,O14974,Q96JM3,P55735,Q86V81,Q9NYB0,Q92878,Q9NZZ3,Q9NQS7,Q7Z7K6,Q14008,P16104,Q9H444,Q9Y6D9,Q15910,Q14203,Q9UQE7,P26358,Q13185,Q9H3R5,Q14807,P33991,P54132,Q9Y6G9,Q13769,Q15019,O94776,P05455,P17544,Q13416,P09874,Q9UEE9,O43237,Q9P0M6,Q96EE3,Q14683 56 +U5 snrnp 0.484658635501438 1.1752100937710777 0.239910672957722 1.0 0.5415805290530755 10 O95400,P62314,Q9BUQ8,O94906,P62304 5 +Flemming body 0.4003626767222741 1.1698022925689933 0.242080540869608 1.0 0.5437868307218782 20 Q9H0H5,O95319,Q96JM3,P53990,Q96KP1,Q9UN37 6 +Box h aca snornp complex 0.63313159265887 1.1632174009742655 0.2447413082243197 1.0 0.5470688066190676 5 Q9NPE3,Q14978 2 +Box h aca rnp complex 0.63313159265887 1.1632174009742655 0.2447413082243197 1.0 0.5470688066190676 5 Q9NPE3,Q14978 2 +Microtubule organizing center 0.3704819353488499 1.1611808145829643 0.2455683751954467 1.0 0.5475754478685756 235 Q13464,Q9UPN4,Q8WWK9,Q12834,Q8TD16,Q16513,P51608,O60271,Q9NZM3,Q7Z4H7,Q96CS2,Q92785,Q9NV06,Q9HD42,Q15398,Q9UN37,O15078,P50402,P33176,Q7Z6E9,O75147,Q9Y448,P25205,Q8WYA6,Q13526,Q02241,Q9Y5K6,P15311,O14974,Q9BV73,Q9H814,Q9H981,Q9BSJ2,Q9UIJ7,P43487,Q86VS8,Q6P1N0,Q14008,P06748,Q13409,P0DMV9,P16104,Q9Y6D9,Q14203,Q9P270,P27816,Q14980,Q9UNZ2,O95721,P62081,P29966,Q9Y6G9,Q9Y6A5,Q96CT7,O60610,Q5VU43,Q14498,P55081,Q15051,Q13432,Q13416,Q9Y496,Q9Y366,Q9HC35,Q9BZI7,O43237,P53990,Q5M775,O75116,P23258,Q96ED9 71 +Fascia adherens 0.5802546669996114 1.1563565567739509 0.2475353435424523 1.0 0.5486523994111151 6 P19022 1 +Cohesin complex 0.6289328223247503 1.1443024371115254 0.2524982329394305 1.0 0.5497896692309584 5 Q14683 1 +Extrinsic component of endosome membrane 0.6773849034061106 1.1407484959451588 0.2539745990866255 1.0 0.5497896692309584 4 P40818 1 +Rna polymerase ii holoenzyme 0.3453003947696321 1.1365739653115687 0.2557164287518731 1.0 0.5497896692309584 30 P35269,Q9NQG5,P23193,P18074,Q96P16,Q9UM54,P29083,O75528,P13984,P24928,Q6P1J9,O15514,Q8N7H5,Q5VT52,Q92541,P32780 16 +M band 0.6761858907450096 1.1356876347474234 0.2560873174593423 1.0 0.5497896692309584 4 O75147,Q01082 2 +Voltage gated calcium channel complex 0.7709481808158811 1.1354022710295648 0.2562068085780233 1.0 0.5497896692309584 2 P54652 1 +Fhf complex 0.7942805166197726 1.1165889785810628 0.264170106207257 1.0 0.5629350377066221 3 Q86VS8 1 +Polymeric cytoskeletal fiber 0.3575398426757543 1.1136355974453005 0.2654355484880335 1.0 0.5630069604368714 196 Q96CS2,Q6SZW1,Q9BRK0,Q92974,Q9BSJ2,P48681,Q9NQS7,Q13409,Q9P270,P27816,Q14980,Q96EY1,Q15149,Q9NR12,O43237,Q5M775,O00159,Q9UQB8,Q9H307,Q96ED9,P04083,Q9UQN3,Q9HD42,Q96HC4,Q02241,Q9Y5K6,Q86VS8,Q9NZZ3,O43795,Q9H444,Q14807,Q9ULW0,Q9Y6G9,Q9Y496,Q8NCM8,P23258,P46821,P07197,Q9Y3E7,Q9H0H5,Q9UHD8,O75347,Q7Z4H7,P46940,O15344,P50402,Q9Y448,Q4VCS5,P16949,Q15555,Q9UM54,Q96IZ0,O75298,Q86Y91,Q08379,Q8WWK9,Q99661,Q9BVA1,O00151,Q03252,P33176,Q13561,Q66K74,Q9UJU6,P15311,P50570,Q14008,P67936,Q00839,Q14247,Q96CW5,Q14203,Q7Z460,P02545,P58107,P0DP25,Q9HC35 77 +Cell body 0.2995192640330255 1.1066504351369937 0.2684450925434583 1.0 0.565408601384836 106 Q13283,Q14249,P55011,P10586,P09104,Q05682,Q9NZI8,O75146,O75592,P25685,Q9H814,O94832,P62753,Q14203,O43815,Q14980,Q9BPU6,Q9H2P0,P46779,O95793,P51610,O75494,P20020,Q14168,Q9UQB8,P21333,Q8N3R9,Q02952 28 +Dendrite membrane 0.6680940040178117 1.1015696013191554 0.2706488300869369 1.0 0.5687367120720888 4 Q14168 1 +Contractile ring 0.5338840363334887 1.0957122646545032 0.2732047136973641 1.0 0.5705775475756584 7 Q96GD0,Q9NQW6,Q96Q89,P35579,P46939 5 +Apical plasma membrane 0.3056279257458699 1.093185987480663 0.2743121481115134 1.0 0.5711705001773978 54 P11166,Q13572,P55011,P36543,Q16625,O75146,P15311,P04920,P19022,P20020,P78536,P05026,O14745 13 +Core mediator complex 0.4967709864196205 1.079241940567699 0.2804798875372793 1.0 0.5763577810294708 8 Q9NPJ6,Q71SY5,Q9NVC6,Q15648 4 +Motile cilium 0.33433449741307 1.067355654423563 0.285811265307776 1.0 0.5831801552281118 33 Q14141,Q9Y366,P05026,Q8NCM8,O14745 5 +Presynaptic active zone membrane 0.5591681597279807 1.0544711830935405 0.2916672472206321 1.0 0.5914163738129637 6 Q12846,P19022,Q9Y639,P20020 4 +Cell cortex region 0.4324574499879357 1.0404079401955844 0.2981504142944988 1.0 0.5982856976968904 13 P09496,Q14980 2 +Cell substrate junction 0.3500344970273661 1.0376345612680733 0.2994402211714244 1.0 0.5988804423428489 189 Q13283,P04083,P35611,Q96N67,P46940,Q14676,P35221,O00151,Q92974,O60504,Q13136,P26038,Q9Y4L1,Q9UNF0,P61247,P18206,Q13740,P62917,P84098,Q6WCQ1,Q09666,Q02241,Q9ULV4,P62841,O14974,Q15942,Q15555,P19022,P15311,Q02878,P50570,P67936,Q14247,Q9Y490,P06748,P0DMV9,P84095,O43491,P62424,P17096,P28838,Q13308,P62273,P04920,Q9UHB6,P62081,Q8N8S7,P62899,O75369,P29966,Q16527,P39019,P35579,P30101,Q15149,P61353,P46777,P58107,P46782,P62263,Q9NR12,P11940,P36578,P05387,Q14315,P40429,P78536,O96013,P21333,P11142,Q02952 71 +Sno s rna containing ribonucleoprotein complex 0.3870466267729032 1.0257386537940325 0.3050147891965746 1.0 0.6073656937713452 19 O00566,Q9NPE3,P55769,O43818,Q14978 5 +Barr body 0.6493283743807576 1.022758921629573 0.306421844797526 1.0 0.6079720965323907 4 O75367,Q9P0M6 2 +Specific granule lumen 0.3982801945115601 1.0166941676076109 0.3092989411658253 1.0 0.6079720965323907 16 P18206,O15078,Q96JM3 3 +Microtubule 0.3225142290426868 1.0153665827523584 0.3099311162958638 1.0 0.6079720965323907 142 P46821,Q96SN8,Q8WWK9,Q9UQN3,Q9Y3E7,Q99661,Q9BVA1,Q9H0H5,Q9UHD8,O75347,Q7Z4H7,Q96CS2,Q96Q89,Q9BRK0,Q6SZW1,Q9HD42,Q92974,P46940,O15344,O00139,P50402,P33176,Q13561,Q9Y448,Q66K74,Q02241,P16949,Q15555,P50570,Q9BSJ2,Q86VS8,Q9NZZ3,Q14008,Q9NQS7,Q00839,Q13409,Q96CW5,Q9H444,Q14203,Q7Z460,Q9P270,P27816,Q14980,Q14807,Q9ULW0,Q9Y6G9,P0DP25,Q9Y496,Q9HC35,Q9UQ16,O43237,Q86Y91,Q9UQB8,Q08379,Q8NCM8,P23258,Q96ED9 57 +Ptw pp1 phosphatase complex 0.5182351282525042 1.0152897488499673 0.3099677295015108 1.0 0.6079720965323907 7 O94842,O14974 2 +Transcription preinitiation complex 0.6468265234263461 1.0122923943302216 0.3113982703124045 1.0 0.6079720965323907 4 P29083,P13984 2 +Flotillin complex 0.5492730186550824 1.0068942627820816 0.3139855893275833 1.0 0.6079720965323907 6 Q9ULV4,P35221 2 +Chromocenter 0.5468807768633075 0.9954219391359042 0.3195310926311534 1.0 0.6134996978518146 6 P45973,Q53HL2,Q9NQS7 3 +Equatorial microtubule organizing center 0.7351157662623989 0.985873945119074 0.32419497387229 1.0 0.6183408213868946 2 Q9BSJ2 1 +Dna polymerase complex 0.423671967189412 0.9833351058245898 0.3254425375720498 1.0 0.6183408213868946 13 P54098,Q9NRF9 2 +Nurf complex 0.5431156935711577 0.9773925527164526 0.3283748485108779 1.0 0.6213233648172628 6 Q12830,Q16576 2 +Dendrite terminus 0.6325476999109423 0.9527854927429767 0.3406987661514375 1.0 0.6378307135451385 4 P08238,Q9Y366 2 +Rpap3 r2tp prefoldin like complex 0.4735449330422201 0.9516088692011871 0.3412953818092408 1.0 0.6378307135451385 8 Q9NUG6,Q9H6T3,O15212 3 +Mitotic spindle astral microtubule 0.7503680229306983 0.948728526064754 0.3427587017238804 1.0 0.6392554927856421 3 Q14980 1 +Proteasome regulatory particle base subcomplex 0.4586204701572735 0.9404423590118244 0.3469907030768673 1.0 0.643202278874193 9 P35998,P62195,P17980,Q99460,P62191,P55036 6 +Gamma tubulin complex 0.6283622988994431 0.9354261045309776 0.3495687490714563 1.0 0.6449386086980285 4 Q9BSJ2,P23258 2 +Synaptic cleft 0.7227122381477696 0.9348070840999568 0.3498877281134362 1.0 0.6449386086980285 2 P11047 1 +Vcp npl4 ufd1 aaa atpase complex 0.533361531813953 0.930853542125105 0.3519293289948211 1.0 0.6449386086980285 6 Q04323 1 +Kinetochore microtubule 0.4269647656201922 0.9256991722708892 0.354602338162437 1.0 0.6467946648082851 12 Q9HD42,Q9H444,Q9UQN3,Q9Y3E7 4 +Ubiquitin conjugating enzyme complex 0.5769891867024384 0.9124062844418724 0.3615548825212344 1.0 0.6542901233518289 5 Q5VTR2,O75150,P61088 3 +Spindle microtubule 0.3083411956824926 0.9109934832359938 0.3622988073384579 1.0 0.6542901233518289 40 Q96CW5,Q9H444,Q9UQN3,Q9Y3E7,Q7Z460,Q14980,Q9Y496,P23258,Q86Y91,Q7Z4H7,Q96CS2,Q9HD42,P0DP25,Q9NZZ3,Q00839 15 +Cytosolic region 0.5276261511489968 0.9036188136317562 0.3661975617677746 1.0 0.6587222412864111 6 Q9UQB8,Q13526 2 +Lamellipodium 0.2818699714469013 0.8926329447195716 0.3720537705580966 1.0 0.6627207788066096 66 Q13464,Q8IZP0,Q16513,Q96GD0,P35221,Q9NZI8,O75955,P35241,Q9ULV4,Q4VCS5,Q14444,Q9UJU6,P19022,P50570,Q14247,O00165,P51809,Q9Y5S2,Q12846,Q9Y6W5,Q8N8S7,P35580,P11940,Q13596,Q9UQB8 25 +Ino80 type complex 0.4194789030042614 0.8794993700363124 0.3791305745319238 1.0 0.6726986069515846 12 Q9NPF5,Q9H981,Q6ZRS2,P25490 4 +Esc e z complex 0.5196191902462559 0.8657834685178762 0.3866089165274435 1.0 0.6783373377941436 6 Q16576 1 +Cytoplasmic region 0.2808586518599004 0.8654874721390968 0.386771289093152 1.0 0.6783373377941436 65 Q9UHD8,P33176,Q92572,O75146,P09496,Q15555,Q6PJT7,Q00839,P23246,Q14203,P27816,Q14980,Q15019,Q8N2K0,Q9Y496,Q14168,Q9UQB8,O60828,Q8NCM8 19 +Postsynaptic cytosol 0.5637707461661002 0.8544087759329736 0.3928785350660768 1.0 0.6809301306858623 5 Q9UQB8,Q13526 2 +Atp binding cassette abc transporter complex 0.7239364656640841 0.8496377536716956 0.3955265152589797 1.0 0.6809301306858623 3 O14678 1 +Perikaryon 0.3376668597769913 0.8466911089767335 0.397167315748379 1.0 0.6821404745056906 24 Q13283,Q14249,P11387,O75592,P09104,Q14168,P21333,Q8N3R9,O94832 9 +Hulc complex 0.6979051819184175 0.8341431780413241 0.404200306337898 1.0 0.6905501025351483 2 O75150 1 +Filopodium tip 0.512832102776852 0.8339036905593873 0.4043352574054486 1.0 0.6905501025351483 6 Q9H4L5,Q8IZP0 2 +Male germ cell nucleus 0.6026249972357387 0.8297252718337293 0.4066941296381845 1.0 0.6921326217310279 4 P16104 1 +Distal axon 0.2806827809758968 0.8295739702907902 0.4067796987366567 1.0 0.6921326217310279 62 P46821,Q8IZP0,O75150,P09104,Q05682,Q7Z406,Q96N67,P46940,Q96Q89,Q9NZI8,Q13561,Q14141,P80723,P50570,Q8WX93,P07900,Q14247,Q9UPT5,P08238,P0DP25,Q2M2I8,O75494,P21333,P11142,Q06787 25 +Trna splicing ligase complex 0.5110197775017182 0.8254234980727275 0.4091311988222443 1.0 0.693545824025812 6 Q92499,Q9BVC5 2 +Exon exon junction complex 0.5548939485988382 0.8158044227717701 0.4146120032837073 1.0 0.7005329624535737 5 Q9HAU5 1 +Juxtaparanode region of axon 0.7139742623734291 0.8128125995492741 0.4163255105809615 1.0 0.7005329624535737 3 Q9Y2J2 1 +Xy body 0.7116073890267416 0.8041118654713887 0.4213323725377162 1.0 0.707652161610308 3 P16104,Q92922 2 +Excitatory synapse 0.503169302565232 0.7888623745436528 0.4301924486872135 1.0 0.7175265146939713 6 Q9UQB8,P23634,Q15334,Q8WX93 4 +Bleb 0.5031080425026517 0.7885782341872635 0.4303585565105288 1.0 0.7175265146939713 6 Q13464,Q9BRK5 2 +Cell body membrane 0.7028204804302207 0.7719856573053488 0.4401229223723337 1.0 0.7272215743780363 3 P55011 1 +Integral component of presynaptic active zone membrane 0.5435097394678178 0.766770456452187 0.4432180046502831 1.0 0.7272215743780363 5 P19022,Q9Y639,P20020 3 +Intrinsic component of presynaptic active zone membrane 0.5435097394678178 0.766770456452187 0.4432180046502831 1.0 0.7272215743780363 5 P19022,Q9Y639,P20020 3 +Rna polymerase complex 0.2898750079123181 0.7664228016312918 0.4434247697868163 1.0 0.7272215743780363 44 Q9NQG5,Q96P16,P13984,P24928,O15160,Q92541,P49642,P23193,P25205,P29083,O75528,Q6P1J9,P35269,Q9UM54,Q5VT52,P32780,O14802,Q8N7H5,O00411 19 +Mrna editing complex 0.7002198237659152 0.762532638249462 0.4457421711374147 1.0 0.7272215743780363 3 Q96T37 1 +Dna repair complex 0.3569047165724633 0.7456697805520345 0.4558669184282351 1.0 0.7395981401008973 17 P20585 1 +Apical junction complex 0.3022383345747553 0.7398149683813547 0.4594122752362128 1.0 0.7417499956547732 32 Q07157,O43815,Q9UDY2,Q16513,Q4VCS5,Q8N3R9,P58107,Q92974,Q13112 9 +Perinuclear endoplasmic reticulum 0.4633396780876881 0.7396257124108795 0.4595271354659505 1.0 0.7417499956547732 7 O60858,P22059 2 +Presynaptic cytosol 0.6919255948796899 0.7325645280831865 0.4638240725881031 1.0 0.742803192905091 3 Q9UQB8 1 +X chromosome 0.5338120642812713 0.7254823924891093 0.4681561429232199 1.0 0.7460211174369449 5 O75367,Q9P0M6 2 +Rna polymerase iii transcription regulator complex 0.5325047881385729 0.7199539069905012 0.4715533756115597 1.0 0.7471219428880461 5 Q9Y5Q8 1 +Transcription factor tfiiic complex 0.5325047881385729 0.7199539069905012 0.4715533756115597 1.0 0.7471219428880461 5 Q9Y5Q8 1 +Prc1 complex 0.6640022050716836 0.7007407182717479 0.4834648400056136 1.0 0.7602067829053787 2 Q99496 1 +Messenger ribonucleoprotein complex 0.5690645640005956 0.6955349813132803 0.4867200966494209 1.0 0.7613871837809124 4 P51991 1 +F actin capping protein complex 0.4800827643061025 0.6832610835204019 0.4944418805061401 1.0 0.7673720124707937 6 P47755 1 +Spectrin associated cytoskeleton 0.5658012481848959 0.6827687044260408 0.4947530080403801 1.0 0.7673720124707937 4 Q12955,Q01082 2 +Chaperone complex 0.3227695774215346 0.6790840871244087 0.4970845845047855 1.0 0.7696793566525711 23 P50991,Q8WXX5,O95816,Q9UBS4,P31948,Q16543,P78371,O95456,P08238,P17987,P11142 11 +Neuron projection cytoplasm 0.2931819225910706 0.6759943966253148 0.4990442026763524 1.0 0.7709254450141452 34 P33176,P23246,Q8N2K0,Q92572,O75146,Q9Y496,Q14168,Q9UQB8,O60828,Q6PJT7,Q00839 11 +Presynaptic membrane 0.3310737187944559 0.669317447704395 0.5032929991930917 1.0 0.7753432690271953 21 Q9NZM3,P19022,P09496,O00291 4 +Axon 0.2938370032034252 0.6603588860874814 0.509023549510988 1.0 0.7802176086622203 135 P46821,P07197,Q8IZP0,Q9Y2J2,O75150,P09104,Q05682,Q7Z406,Q96N67,P46940,Q6SZW1,Q13136,Q9NZI8,P33176,Q13740,Q92572,Q9Y5K6,Q14141,O75592,P80723,Q6PJT7,Q14247,O94832,Q14203,P11274,P27816,Q15075,Q01082,Q9ULW0,P08238,Q12979,Q9H2P0,Q15149,P51956,Q2M2I8,Q9Y496,O75494,Q8N3R9,Q14168,P21333,P11142 41 +Myelin sheath adaxonal region 0.6671415730724075 0.6448490845910703 0.5190249895933929 1.0 0.789397576273766 3 Q8N3R9 1 +Ino80 complex 0.471427368187999 0.6445540627939691 0.5192162121232706 1.0 0.789397576273766 6 Q9H981 1 +Anchoring junction 0.3403848241006958 0.6321286209695515 0.5273028344518171 1.0 0.7961923593047305 270 Q96GD0,Q14676,Q92974,Q9UNF0,P62917,P84098,Q07157,Q09666,P62841,O14974,Q15942,P06748,P0DMV9,P62424,Q9UHB6,P62081,P62899,P05026,Q15149,Q9NR12,Q9UDY2,Q16625,P55196,Q14315,P40429,Q9UQB8,Q9H307,Q9BY67,P04083,Q96N67,Q96HC4,Q9Y4L1,O75147,Q02241,Q9Y5K6,P19022,Q9Y5S2,Q9Y490,P84095,P17096,P28838,Q13308,P04920,Q9NYL9,P35579,P61353,P46782,P62263,P11940,P78536,P22314,P11142,Q8N3R9,Q02952,Q13283,Q9Y2J2,P35611,P46940,P11802,P61247,P18206,Q13177,Q13740,Q9ULV4,Q4VCS5,O43815,O43491,O75369,P29966,P39019,P11166,Q5EBL8,P21333,Q16513,Q13136,Q6WCQ1,P15311,Q02878,Q14247,Q86VI3,P62273,P30101,P46777,P58107,P05387,Q14168,O96013,Q13112 88 +Basolateral plasma membrane 0.2675518245746487 0.6295915176974664 0.5289618746785965 1.0 0.7967663370546594 52 Q9BY67,Q07157,P11166,P55011,P15311,P04920,P19022,P20020,Q14168,P05026,P58107,O94832,Q5EBL8 13 +Photoreceptor outer segment 0.3898388314880088 0.6262852812136555 0.531127838798436 1.0 0.7967663370546594 10 Q9BV73,P46821,Q15051,Q15555 4 +Extrinsic component of membrane 0.2585187978069908 0.6259843271791964 0.5313252213619162 1.0 0.7967663370546594 69 P04083,Q9H0H5,O75150,Q8NC60,O95747,P46940,A0FGR8,Q6SZW1,Q9UNF0,P40818,P12270,P15311,P19022,Q9BZE9,P62942,Q14980,Q15075,Q9UJZ1,Q96EY1,O00291,Q2M2I8 21 +Mll1 2 complex 0.3543470003103303 0.6189800858595215 0.5359294779227799 1.0 0.7999471094362934 14 P51610,Q99496,Q15291,Q9HCK8 4 +Catalytic step 1 spliceosome 0.3990490299936642 0.6152144641184606 0.5384130968535894 1.0 0.8023410855073098 9 Q9BW85,Q9ULR0 2 +Neuronal ribonucleoprotein granule 0.6581417310577258 0.6137674601157791 0.5393690027893117 1.0 0.8024543728284702 3 O60828 1 +Polar microtubule 0.6563404308888042 0.6076010061147253 0.5434521333727884 1.0 0.8045914701882841 3 P23258 1 +Collagen containing extracellular matrix 0.2867700181652412 0.5979338606317418 0.5498840653212296 1.0 0.8097125997345446 32 P04083,P52272,P49257,P11047,P50454,Q13043,P19022,Q32P28,P51858,P84157,P07942 11 +Lateral plasma membrane 0.3111647282361682 0.5897387837898883 0.5553657892437451 1.0 0.8142983919458129 23 P04083,P55011,Q14980,Q86VI3,P46940,P05026,O00159,Q13112 8 +Sex chromatin 0.6484770329372509 0.5809057584281335 0.5613039711413728 1.0 0.8171223578894575 3 Q99496 1 +Ruffle membrane 0.2831273125882987 0.5657581623549791 0.5715581909086835 1.0 0.8253432102951284 32 Q96GD0,Q9UM54,O75146,P15311,P78536,Q92974,Q9Y490 7 +Mitotic spindle midzone 0.3892995963102061 0.5651843724321972 0.5719483650290802 1.0 0.8253432102951284 9 Q14980,Q00839,Q14247,Q86Y91 4 +Nuclear pore central transport channel 0.5337861816697269 0.5609174113602708 0.574853839938394 1.0 0.8268011781801989 4 Q8NFH5 1 +Apicolateral plasma membrane 0.4515936052171399 0.5581109241072407 0.5767686414795661 1.0 0.8268011781801989 6 P19022,P58107 2 +Retromer complex 0.3769410384158783 0.5574825477979297 0.5771977797786052 1.0 0.8268011781801989 10 O60493,Q9UNH7,Q5VZ89,Q13596,Q9UMY4 5 +Eukaryotic translation initiation factor 4f complex 0.3979599117520485 0.5570524231079017 0.5774916123912135 1.0 0.8268011781801989 8 P23588,Q15056 2 +B wich complex 0.4242574236660569 0.5550030981400951 0.5788925413325412 1.0 0.827507833378178 7 O60264,Q9NR30,Q9UIG0,Q9NY93 4 +Scar complex 0.4476246977188634 0.5412395412488125 0.5883424864060962 1.0 0.8358815963793802 6 Q8IZP0 1 +Histone methyltransferase complex 0.2995674197412123 0.5397048875253159 0.5894005688333073 1.0 0.8359771676142709 24 P45973,Q15910,Q16576,Q99496,Q15291,P51610,Q9HCK8 7 +Ciliary tip 0.383025259568433 0.5336537781351587 0.593581093819711 1.0 0.8373146535516404 9 Q8NCM8,Q9Y496,Q9Y366 3 +Actin based cell projection 0.2586128993016109 0.5330254144344789 0.5940159877718325 1.0 0.8373146535516404 51 O14745,Q8IZP0,Q9UM54,P26038,P36543,Q01650,Q9UQB8,P15311,Q9H4L5,Q06787,Q8N8S7,O00159,Q9NZI8,P46939,O94832,O43795 16 +Atac complex 0.4440370347850958 0.5261238760701384 0.5988021405217783 1.0 0.842758568141762 6 Q9NRF9 1 +Mitochondrial pyruvate dehydrogenase complex 0.4434326710816988 0.5235905384473835 0.6005633637108088 1.0 0.8439349579418453 6 P08559,P10515,P09622,O00330,P11177 5 +Box h aca telomerase rnp complex 0.5227532122626833 0.5205852310820442 0.6026557398759493 1.0 0.8450586136781728 4 Q9NPE3 1 +Transcription factor tfiid complex 0.389943199400425 0.5184522308328006 0.6041427808313253 1.0 0.8450586136781728 8 Q00403,P23193,P18074,P29083,P35269 5 +9plus2 motile cilium 0.3008799590688044 0.5137085955383415 0.607455741477255 1.0 0.8470942449958052 23 Q14141,O14745,P05026 3 +Axonal growth cone 0.4806406054582747 0.5098115426510142 0.6101834982970047 1.0 0.847911156658646 5 P08238,P21333 2 +Postsynaptic endocytic zone 0.625787756926121 0.5061003162155963 0.6127862285880792 1.0 0.8491788641214375 3 P09496 1 +Oxoglutarate dehydrogenase complex 0.622277364212845 0.4948473149739301 0.6207079025532649 1.0 0.8526076619470343 3 P09622,P36957 2 +Proton transporting atp synthase complex catalytic core f 1 0.5154440154440102 0.4944099142186112 0.621016713647127 1.0 0.8526076619470343 4 P25705,P36542,P06576 3 +Synaptic membrane 0.2549462552517361 0.4921292670613201 0.6226279636586896 1.0 0.8526076619470343 53 P09104,Q9NZM3,P46939,O75146,Q9UJU6,P09496,P19022,P50570,Q9Y639,Q12846,O43815,Q96EY1,O00291,O75251,Q15334,Q9UQ16,P20020,Q14168,Q9UQB8,P11142,Q06787 21 +Somatodendritic compartment 0.2947035330229641 0.4877155205469133 0.6257513567277859 1.0 0.8556000559756233 155 P46821,Q13283,Q14249,P11387,P55011,P98179,P10586,P09104,Q05682,Q6SZW1,Q13136,Q9NZI8,P40818,P33176,Q13740,Q9Y5K6,Q14444,O75592,O75146,P25685,Q9H814,Q6PJT7,Q14247,O94832,P62753,Q12846,P23246,Q14203,P11274,O43815,Q14980,Q9BPU6,Q9ULW0,P08238,Q12979,P46779,Q15149,O75251,Q9H2P0,Q8N2K0,O95793,P42345,P51610,O75494,Q9Y366,P20020,Q8N3R9,Q14168,Q9UQB8,P21333,P11142,Q02952 52 +Dihydrolipoyl dehydrogenase complex 0.4722570041360916 0.4779309361748727 0.6326993617915908 1.0 0.8638051166975013 5 P09622,P36957,Q02218 3 +Post mrna release spliceosomal complex 0.369795658559544 0.4691002693145714 0.6389979665852554 1.0 0.8672115260799895 9 Q9ULR0,P52272,P16383,Q9UBB9,Q8WUD4 5 +Intrinsic component of nuclear inner membrane 0.4037616900627796 0.4645174982583792 0.6422770257631654 1.0 0.8703664895928779 7 Q9Y2U8,Q8NC56 2 +Postsynaptic cytoskeleton 0.5950937155457452 0.4522014274547761 0.6511238799377779 1.0 0.8780951289865311 2 P07196 1 +Parallel fiber to purkinje cell synapse 0.595093715545745 0.4522014274547755 0.6511238799377783 1.0 0.8780951289865311 2 P23634 1 +Zona pellucida receptor complex 0.4620428333069572 0.440062324536247 0.6598919681629298 1.0 0.8850315808302823 5 P50991,P78371 2 +Presynaptic cytoskeleton 0.6038047973531812 0.4372002302685699 0.6619661427625587 1.0 0.885633018948332 3 Q8IUD2,Q9UH03 2 +Histone pre mrna 3 end processing complex 0.590407938257983 0.4367638938265539 0.6622825865381168 1.0 0.885633018948332 2 O60506 1 +Phosphatase complex 0.2994238836741475 0.4252216406325503 0.6706751099341552 1.0 0.8916263852185855 20 O94842,O14974 2 +Myelin sheath 0.3182817271200803 0.4105929122729598 0.68137106173303 1.0 0.8982224142962636 14 Q12846,Q8N3R9,P0DP25,Q15149,O94832 5 +Growth cone membrane 0.5804851157662517 0.4048141338450661 0.6856141387667898 1.0 0.9005614219886724 2 Q9UPT5 1 +Main axon 0.3453906979138773 0.4004188465110399 0.6888480453027608 1.0 0.9008035162933704 10 Q9Y2J2,Q14168,O94832,Q01082 4 +Mitochondrial small ribosomal subunit 0.3004084496666814 0.3969474565376456 0.691406207681315 1.0 0.9008035162933704 18 Q9BYN8,P82912,Q9Y291,P82650,P82673 5 +Dendritic spine membrane 0.5882875236321272 0.3909834183526986 0.6958094924987779 1.0 0.9035219650938254 3 P20020 1 +U2af complex 0.5822903476365419 0.3737056457664128 0.7086233244742197 1.0 0.915388770425621 3 Q15637 1 +Clathrin vesicle coat 0.3108660602131418 0.3716653696097429 0.7101420118964525 1.0 0.9160530620220152 14 P09496,Q14677 2 +Mitotic spindle microtubule 0.3567858363513989 0.369340445949842 0.7118739818372026 1.0 0.9164816287612778 8 Q7Z4H7,Q96CS2,P23258 3 +Male pronucleus 0.566152149944862 0.3605477204785162 0.7184375769724844 1.0 0.9205003088913972 2 P83916 1 +Sarcoplasmic reticulum lumen 0.4754814162166252 0.3602820703785614 0.7186362060643363 1.0 0.9205003088913972 4 O43852 1 +Tricarboxylic acid cycle enzyme complex 0.3253815086105719 0.3547099550677727 0.7228068922276842 1.0 0.9221859914816378 12 O43837,P09622,Q96I99,P53597,P36957,Q02218 6 +Intrinsic component of postsynaptic specialization membrane 0.4003568920466842 0.354306525653738 0.723109177787632 1.0 0.9221859914816378 6 P19022,Q15334,Q9Y639 3 +Chaperonin containing t complex 0.3522915516289326 0.350650932658813 0.7258502409336207 1.0 0.9221859914816378 8 P50991,P40227,P78371,P48643,P49368,P17987,P50990 7 +Mitochondrial tricarboxylic acid cycle enzyme complex 0.3493179807020892 0.3385102932940459 0.7349786715420334 1.0 0.9273021040757624 8 P09622,P53597,O43837 3 +External encapsulating structure 0.2504639120241742 0.3378225130699923 0.7354969432911522 1.0 0.9273021040757624 37 P55081,P04083,P52272,P49257,P11047,P50454,Q13043,P19022,P51858,P07942 10 +Plasma membrane raft 0.2848074135826799 0.3375656231708921 0.7356905516961276 1.0 0.9273021040757624 20 P19022,P11166,P15311,P05026 4 +Dopaminergic synapse 0.5581587651598632 0.3368859657640419 0.7362028652614387 1.0 0.9273021040757624 2 O75955 1 +Filopodium 0.2537667377727182 0.3344615553491422 0.7380312965141043 1.0 0.9273021040757624 33 Q8IZP0,Q9UM54,P15311,Q9H4L5,Q06787,Q9NZI8,Q8N8S7,Q9UQB8,P26038,P46939,O14745,O43795 12 +Ciliary plasm 0.2880670384525953 0.3276929230002952 0.7431438548339764 1.0 0.9298850502169904 18 P27816,Q8NCM8 2 +Transcription elongation factor complex 0.2830312922933984 0.3274913640201295 0.7432962736931863 1.0 0.9298850502169904 20 P18615,Q92541 2 +Endoplasmic reticulum lumen 0.2327747391917821 0.3257329072913593 0.7446264444923489 1.0 0.9302730375027702 69 P13667,Q7Z4H8,Q9NYU2,Q96AY3,Q32P28,Q9Y4L1,P07942,P30533,Q86UP2,O43852,P50454,P19022,Q5JRA6,Q14697,P30040,P11047,P30101,Q8NBS9,P14314,Q13438,P78536 21 +Methyltransferase complex 0.2429614598716077 0.3035089509615555 0.7615020271109114 1.0 0.9417955410246874 42 P45973,Q15910,Q16576,Q96T37,Q15007,Q99496,Q15291,P51610,P62314,Q9HCK8,Q96FX7 11 +Dna replication preinitiation complex 0.3188802663183817 0.3027100141886218 0.7621108654344511 1.0 0.9417955410246874 11 P33991,P25205 2 +Smn sm protein complex 0.3203731970702644 0.2905484943181882 0.7713966568568633 1.0 0.9468556541769304 10 P62316,P62314,P62304,Q9UHI6 4 +Protein complex involved in cell adhesion 0.4489795918367242 0.2812805749561273 0.7784952080526 1.0 0.9517260452332053 4 P06756,P17301,Q9BX67 3 +Swr1 complex 0.3318327542841756 0.2709857014247646 0.7864020295612355 1.0 0.9562648679464624 8 Q9NPF5,Q6ZRS2 2 +Clathrin coated pit 0.2434663782365932 0.2628833486444848 0.7926404909071665 1.0 0.9574677188176632 33 Q9UM54,Q2M2I8,O75146,Q9NZM3,P09496,Q14247 6 +Centriolar subdistal appendage 0.5365716837631641 0.2539942601492054 0.7994999924652206 1.0 0.9593358317689952 3 Q14203 1 +Dendritic growth cone 0.5337292972833452 0.2473086570789875 0.8046693594660987 1.0 0.9593358317689952 3 P08238 1 +Crd mediated mrna stability complex 0.3678908652350461 0.2449117430790355 0.8065247688870101 1.0 0.9593358317689952 6 Q9NZI8,Q00839 2 +Plasma membrane protein complex 0.2227267030023183 0.2431854302996847 0.8078617530686274 1.0 0.9593358317689952 71 Q09666,O14678,Q9NP58,P09496,P19022,P30511,P05026,P46939,O14745 9 +Pseudopodium 0.3224026512726317 0.2375034822132439 0.8122662180634492 1.0 0.9604307258768228 8 P27361,O43707,P26038,P12814,P51809 5 +Cilium 0.2351545759842789 0.2340869050374518 0.8149175118056691 1.0 0.9604307258768228 105 P46821,Q9UPN4,P04083,Q9UHD8,O15078,P33176,Q13526,Q04721,Q14141,Q9GZT3,P15311,Q9BV73,Q15555,O14745,Q14203,P54819,P27816,Q9H4M9,O95721,P05026,Q15019,Q15051,Q9Y496,Q9Y366,Q8NCM8,P23258 26 +Phagocytic vesicle 0.2265238462813554 0.23244749754029 0.8161904612973776 1.0 0.9604307258768228 52 O60493,O43752,P42345,Q6WKZ4,O14964,P30511,P30101,O75369,O00159,P33176 10 +Endolysosome membrane 0.3067650121512992 0.2095551895601465 0.8340148565610768 1.0 0.9717114160752568 9 Q9NP58 1 +Cul4 ring e3 ubiquitin ligase complex 0.3130336584445802 0.2064208727797119 0.8364621677858599 1.0 0.9717878942938908 8 Q5TAQ9,Q13620,Q9NV06,Q9BW61 4 +Mhc class i peptide loading complex 0.3833077776965137 0.1940346344331597 0.8461487628743194 1.0 0.9805434202558824 5 P30101 1 +Schaffer collateral ca1 synapse 0.2576830877018753 0.1907334954811595 0.8487343948129453 1.0 0.9810466008484234 19 P11274,O14908,Q9BVA1,Q9Y639,Q9UQB8,Q12979,Q02952 7 +Integrin complex 0.5058533707393016 0.1868404782821559 0.8517857086426974 1.0 0.9833272990913166 3 P17301 1 +Dynein axonemal particle 0.3405153211179642 0.1677258161431789 0.8667989855509246 1.0 0.9931164256563356 6 P31948 1 +U12 type spliceosomal complex 0.262822423454857 0.1633999662479684 0.8702035294564949 1.0 0.9949461727292264 14 Q13435 1 +Beta catenin tcf complex 0.4790518191841087 0.1481232274564188 0.8822455187838845 1.0 1.0 2 Q04726 1 +Paranodal junction 0.4785005512679013 0.1471188529718076 0.883038209274702 1.0 1.0 2 O15020 1 +Intrinsic component of presynaptic membrane 0.3309592748611613 0.1443400123496286 0.8852319838202054 1.0 1.0 6 P19022 1 +Integral component of synaptic vesicle membrane 0.3284199393976336 0.13844497638393 0.8898887532141491 1.0 1.0 6 O43752 1 +Cytoplasmic microtubule 0.2329623095876401 0.1379076728743243 0.8903133862780133 1.0 1.0 24 Q99661,Q14980,Q15555,Q86Y91,Q9BSJ2,Q9BRK0,O15344,P23258 8 +Dendritic tree 0.2365384280080263 0.1328489929030413 0.8943128069881023 1.0 1.0 120 P46821,P98179,Q6SZW1,Q13136,Q9NZI8,P40818,P33176,Q13740,Q66K74,Q9Y5K6,Q14444,O75146,Q9UJU6,P25685,Q6PJT7,Q14247,O94832,Q00839,P62753,Q12846,P23246,P11274,O43815,Q14980,Q9BPU6,P08238,Q12979,P46779,Q15149,Q9H2P0,Q8N2K0,O95793,P42345,O75494,Q9Y366,P20020,Q14168,Q9UQB8,P11142 39 +Condensin complex 0.3043311948165202 0.1281041193691866 0.8980665761258322 1.0 1.0 7 O95347 1 +Alpha dna polymerase primase complex 0.3513989113736204 0.1227854224009178 0.9022770181435728 1.0 1.0 5 P25205 1 +Picln sm protein complex 0.3507529300090507 0.1215312370709141 0.9032702744613386 1.0 1.0 5 P62314,P62304 2 +Site of polarized growth 0.2095162036129449 0.1175949288557039 0.9063886232533857 1.0 1.0 52 P46821,Q8IZP0,P09104,Q7Z406,Q96N67,P46940,Q96Q89,Q9NZI8,Q13561,Q9UJU6,P80723,P50570,Q8WX93,P07900,Q14247,Q9UPT5,P08238,P0DP25,P21333,Q06787 20 +Er to golgi transport vesicle membrane 0.2131668581915853 0.0990047028521308 0.9211345361162347 1.0 1.0 27 P49257,O15027,P55735,Q15437,P30511 5 +Postsynaptic density intracellular component 0.3646085623079171 0.0965760417065261 0.9230630834874184 1.0 1.0 4 Q9UQB8 1 +Postsynaptic specialization intracellular component 0.3646085623079171 0.0965760417065261 0.9230630834874184 1.0 1.0 4 Q9UQB8 1 +Cop9 signalosome 0.2568033105943271 0.0961337145392826 0.9234143749700384 1.0 1.0 11 Q99627,P62993,Q9H9Q2,Q9UBW8 4 +Postsynaptic specialization membrane 0.2469231184357268 0.0955700248247815 0.9238620729227311 1.0 1.0 13 P19022,P11142,Q14168,Q9Y639 4 +Nuclear replication fork 0.232440064353442 0.0949330433798241 0.9243680102131258 1.0 1.0 17 O75717,Q9UNS1,Q9UIG0,P25205 4 +Mitochondrial alpha ketoglutarate dehydrogenase complex 0.4499586435070256 0.0946453483157211 0.9245965287342096 1.0 1.0 3 P09622,O14874 2 +Vesicle coat 0.2077870643180586 0.0838403755412803 0.933183345970226 1.0 1.0 36 Q14677,P61923,P09496,P55735,Q15437,Q9NVZ3 6 +Apical dendrite 0.3274905268159505 0.0813444699628187 0.9351680092275114 1.0 1.0 5 O94832 1 +Replisome 0.2465450525152045 0.0802248957322029 0.9360583900429762 1.0 1.0 12 P49642,P15927,P35244,P28340,P25205,Q9Y2S7,P09884,Q14181,P49005,P27694,P12004 11 +Extrinsic component of organelle membrane 0.2240025441471399 0.074252089878098 0.9408097984778948 1.0 1.0 15 Q8NC60,P04083,P40818,Q6SZW1 4 +Neuron projection 0.2906108541517901 0.0730805922709424 0.9417419854803564 1.0 1.0 246 Q9BY67,P46821,P07197,P11142,Q8IZP0,Q9Y2J2,P55011,O75150,P98179,P10586,P09104,Q05682,Q7Z406,Q96N67,P46940,Q6SZW1,Q13136,Q9NZI8,O15078,P40818,P33176,Q13740,Q92572,Q9Y5K6,Q14141,Q14444,P16949,P25685,Q9BV73,P19022,O75592,Q15555,O75146,P80723,Q6PJT7,Q14247,O94832,O14745,P51809,Q12846,P62753,P23246,Q14203,P11274,O43815,P27816,Q14980,Q9BPU6,Q15075,Q01082,Q9ULW0,P08238,Q15019,P46779,Q15149,Q12979,O75251,Q9H2P0,Q15051,Q8N2K0,P51956,O95793,P42345,Q2M2I8,Q9UQB8,Q9Y496,O75494,Q9Y366,P20020,Q14168,P51991,O00159,O60828,P21333,Q8N3R9 75 +U4 snrnp 0.294431882439062 0.0725227073495329 0.942185935195318 1.0 1.0 6 P62314,P62304 2 +Replication fork 0.204771702236128 0.0724267940982905 0.94226226217702 1.0 1.0 36 P16104,P25205,O60934,Q9NPF5,P26358,Q9UNS1,P54132,P35251,O75717,Q9UIG0 10 +Lamin filament 0.4228529194310427 0.0636940627839165 0.9492138323612508 1.0 1.0 3 P02545 1 +Sarcoplasm 0.2143680537276751 0.0554330127696483 0.9557934958744394 1.0 1.0 20 O75298,O43852,Q15149,O00165,P35573 5 +Telomerase holoenzyme complex 0.2329061982319721 0.0539466813808085 0.95697764442622 1.0 1.0 12 Q9NPE3,O60832,P62304 3 +Axon cytoplasm 0.2072548024911699 0.0441412056251199 0.9647918474384672 1.0 1.0 22 Q6PJT7,Q14168,Q9Y496,P33176 4 +Sperm principal piece 0.3953680727874226 0.0405638899624424 0.9676435720844798 1.0 1.0 3 P23634,P08237 2 +Eukaryotic translation initiation factor 2 complex 0.3110865968008904 0.0351745364310555 0.971940566647232 1.0 1.0 4 P20042,Q9BY44,P05198 3 +Sumo ligase complex 0.2808275862069003 0.0281529700560166 0.9775401467988808 1.0 1.0 5 Q96SB8,P49792,Q8IY18,P46060 4 +Gpi anchor transamidase complex 0.2923331494760151 0.0224308715074731 0.9821042546408908 1.0 1.0 4 Q92643,O43292,Q969N2 3 +P body 0.1876772282740846 0.0209693660545356 0.9832700926475322 1.0 1.0 35 Q5T6F2,O75175,P11387,Q6P2E9,Q14444,P17980,Q8IZD4 7 +Set1c compass complex 0.2376542008015084 0.0118623508278175 0.9905354353884586 1.0 1.0 6 P51610 1 +Striated muscle thin filament 0.2541314222879491 0.0114662443204591 0.9908514611537412 1.0 1.0 5 Q9NYL9 1 +Inhibitory synapse 0.3004410143329559 0.0099589717327838 0.9920540215616608 1.0 1.0 2 Q9Y639 1 +Anchored component of plasma membrane 0.3181692859112167 0.0089787619645546 0.9928360807104936 1.0 1.0 3 Q9NQX3,Q15334 2 +Nuclear lamina 0.2253211681887309 0.005213361541642 0.9958403581586291 1.0 1.0 6 P02545 1 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6dcea27828defb0f7596d9f22f4c14921b76d4f9 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Axonemal microtubule", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bbsome", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc complex", "Blood microparticle", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Chylomicron", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine head", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mks complex", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Mon1 ccz1 complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spherical high density lipoprotein particle", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiia complex", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOC1", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC10", "ARMCX3", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG3", "ATG5", "ATG7", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C10orf76", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C2CD2L", "C2CD5", "C2orf49", "C3orf58", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CAST", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC86", "CCDC93", "CCDC94", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPH", "CENPK", "CENPP", "CENPU", "CENPV", "CEP131", "CEP170", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLU", "CMPK1", "CNN3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM173A", "FAM207A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FNBP1", "FNBP4", "FNDC3A", "FNTA", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC1", "FUNDC2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GGA1", "GGCX", "GGH", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLYR1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH11", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEBP2", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "ISOC1", "IST1", "ISY1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPK1", "ITSN2", "IVD", "JAGN1", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KNOP1", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC45", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METTL1", "METTL13", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD8", "MGAT1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTF2", "MTFP1", "MTFR1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MVD", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C3A", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANX1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAWR", "PAX6", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD11", "PDZD8", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PEX6", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF5A", "PHF6", "PHF8", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN23", "PTPRF", "PTRH2", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PXMP4", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN2", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCOC", "SCP2", "SCRIB", "SCRN1", "SCYL1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L2", "SKP1", "SKP2", "SLAIN2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAMM41", "TAP1", "TAPBP", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TCTN3", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THADA", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM32", "TRIP12", "TRIP13", "TRIP4", "TRIT1", "TRMT10C", "TRMT112", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPYL1", "TSR1", "TTC1", "TTC19", "TTC26", "TTC37", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UGT8", "UHRF1", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMA21", "VMP1", "VPS13A", "VPS13D", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "VWA8", "WAPL", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", 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"ATP1B1", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP6V1D", "ATP6V1E1", "ATXN2L", "BAG2", "BAIAP2", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BCKDK", "BCLAF1", "BCR", "BICD2", "BIRC6", "BLM", "BMS1", "BOP1", "BPTF", "BRD2", "BRD3", "BRD4", "BTF3", "BUD23", "BUD31", "C2orf49", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CALU", "CAPRIN1", "CAPZA2", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCDC12", "CCDC124", "CCDC137", "CCDC86", "CCDC94", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT8", "CD2AP", "CD2BP2", "CDC20", "CDC37", "CDC42BPB", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDK4", "CDK5RAP2", "CDKN2A", "CDKN2AIP", "CELF2", "CENPH", "CENPU", "CENPV", "CEP131", "CEP250", "CEP290", "CFDP1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD4", "CHD7", "CHD8", "CHMP1A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHTF18", "CHTOP", "CKAP2", "CKAP5", "CLASP1", "CLINT1", "CLTA", "CNOT3", "COPS7A", "COPS7B", "COPS8", "COPZ1", "CORO1C", "CPSF2", "CPSF6", "CPSF7", "CSRP2", "CSTF1", "CSTF2", "CTNNA1", 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sha256:e4c86e99295b37b02e751999557fb750a13eaffa2a29eb0e42c1d7b5eb71ed65 +size 152330 diff --git a/msigdb_gomf/basic/plot_9.png b/msigdb_gomf/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..fc88d36184bd6af59c71063fdc4b9a9fd880aaab --- /dev/null +++ b/msigdb_gomf/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1b8187bbd953b01873c48f0b306a71ad85cd1f1a5966b3519f0881c9b2ab1dcf +size 152037 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7ded8430e26a96f54e560aa03751998155bc0572 --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94b4d3bd0a09c56e60395ee5cde7425208f999ad1fbc5b433f17df134f661ccb +size 202057 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2cf3b2b8a477585725837e3f0be8375cefe7d6e9 --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,52 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Rna binding 355 1005 11.02673461272453 2.839899258795642e-28 331.8203883495146 957.0970873786408 -2.926245807393257 0.1698803240410153 92.26090469842312 51.71359975174448 3.026180805637489 0.3115649032545627 1.0 2.3503419860298204e-06 1.113019285422853e-12 6.8751913877578e-26 5.1897905610201e-47 +Calmodulin binding 23 43 4.267140942515676 1.979940791962953e-05 11.16747572815534 38.22572815533981 -0.1620605886192443 0.6297107045220356 4.998408527002264 5.412141887422726 0.8043602737197835 0.3033117354506625 1.0 0.1201931014379405 0.031778301752159 0.0102035722005359 8.339866005431068e-05 +Protein c terminus binding 18 57 4.020209935105467 5.814630254419306e-05 16.70145631067961 53.91019417475728 -0.5407075898659492 0.562986692788132 7.622507411500661 5.79246187086311 0.7890720675805295 0.310971074214726 1.0 0.0408125099476932 0.000835455600612 0.0001172886788481 0.0090876182913912 +Actin filament binding 36 77 3.946942917360667 7.91554193539934e-05 26.25 71.84223300970874 -0.9304321960479518 0.4613708018520663 9.86747747149622 6.173609891411794 1.1668688337197617 0.3704667377078086 1.0 0.5359669486531639 0.4510721126516604 0.0369197255027244 1.1063569357575612e-07 +Transcription corepressor activity 22 56 3.706017775610869 0.0002105435289887 18.436893203883496 50.929611650485434 -0.8253332662431122 0.4600349910475984 7.242565525859023 6.715248323283318 0.9275182609032726 0.3397606810654651 1.0 0.1760534030430948 0.0658139566612362 0.0014922284967668 0.0036231120919512 +Transcription coactivator activity 48 94 3.633758766233081 0.0002793220356678 24.08009708737864 83.08009708737865 -0.5258977984673134 0.5623358269523376 9.700910376170702 9.707163403888766 0.8135459441502219 0.3180741324886006 1.0 0.3244854389831326 0.0832926376476448 0.013866021969047 0.0226589876229018 +Cytoskeletal motor activity 16 27 3.5976444504925937 0.0003211121655815 10.473300970873789 26.73543689320388 -0.4342441626779736 0.5825299045079992 4.982178509028385 3.406220259996373 0.9094169194572008 0.3345792341522519 1.0 0.3058671484100957 0.163965403057363 0.1079193974753917 0.0029972169690089 +Chromatin dna binding 27 40 3.530976449516092 0.0004140286095726 15.33495145631068 36.890776699029125 -1.444765419831122 0.2916495190963049 5.706361783436864 3.1299077778282047 1.2434348487727178 0.331211651748419 1.0 1.0 1.0 0.003163776372636 0.0048410909429686 +Structural constituent of ribosome 50 121 3.317303875799725 0.0009089070264132 50.27427184466019 111.97330097087378 -1.0968665227712266 0.3627287132905895 16.025617180726236 5.646698990732621 1.8496256179403383 0.3775330956912056 1.0 0.0388797865793584 1.8120066414605656e-05 4.970849884153057e-06 1.016171940595083e-09 +Transcription coregulator activity 80 155 3.310764750794615 0.000930413916711 40.71601941747573 137.51941747572815 -0.6282271932164946 0.5364759484324475 15.223558508756284 16.404833281703027 0.8698107769384127 0.3387576371118048 1.0 0.1505187106346842 0.0081362890047421 0.0002672351520827 8.042865054243432e-05 +Unfolded protein binding 39 64 3.27044752451465 0.0010737746225308 17.296116504854368 57.86407766990291 -0.291354033179967 0.6891157346004377 7.7475135044083485 3.3517088633482173 0.7616295354677189 0.309719733575269 1.0 0.3928429005031874 0.6322723581240091 0.2354116994817763 0.2219073979752139 +Nuclear receptor binding 25 50 3.236573492533161 0.0012097407134832 13.820388349514564 42.327669902912625 -0.6625963317518487 0.5340330787536584 5.896499854048697 6.234254839641945 0.7459511717247959 0.3238094573723026 1.0 1.0 0.683314509064718 0.317240385521931 0.2045307840380992 +Nucleosomal dna binding 18 25 3.1481312001054933 0.0016431792395403 10.235436893203884 21.618932038834952 -1.471960728060783 0.2620471468888282 3.943829708581416 1.7523717146910474 1.2449171753551385 0.3134581971256071 1.0 1.0 1.0 0.0462975654587087 0.0046837779345005 +Mrna 5 utr binding 10 22 3.0993638739970315 0.0019393667439588 8.25 21.37378640776699 -0.4154011794749637 0.5833818526896123 4.354790354210661 0.7543351943574681 0.871904550615986 0.3340646250588486 1.0 1.0 0.2186221342412543 0.0029748064909912 0.0001398373652982 +Cis trans isomerase activity 9 30 3.0740566361680486 0.0021116933956499 5.888349514563107 25.25728155339806 0.2561980004465105 0.5812219045702732 3.257874730761561 2.895731775037304 0.9309473322387666 0.3210818323454172 1.0 0.1706778675257841 0.3128615540599918 3.2281299696419874e-05 6.630630328822088e-05 +Cis regulatory region sequence specific dna binding 26 59 3.033008402406717 0.0024212885823782 15.349514563106796 49.00485436893204 -0.5301040715037881 0.5551007655193639 7.60615328043789 8.367469124048107 0.8572832506411839 0.3311423757958759 1.0 0.9597513763575738 0.9877475215107548 0.995871469641306 0.9983964263671564 +Actin binding 54 121 2.977965233654269 0.0029016889672286 38.72572815533981 112.15533980582524 -0.7899009064120948 0.4963373262830207 13.917754889665892 10.402816349014728 1.1187895183987704 0.3590185078390425 1.0 0.4419616026060442 0.5770915393549105 0.1278645098730017 7.691296733502066e-05 +Transcription regulator activity 98 189 2.917603056516601 0.0035273306581116 51.04126213592233 166.34223300970874 -0.7015814467966277 0.525508951820667 18.56112301902558 22.582359789323267 0.8616135282284574 0.3341828785266304 1.0 0.648990369282783 0.5357144889169081 0.7090224489008703 0.7985973037935816 +Mrna binding 73 171 2.886630215210315 0.0038939158065851 50.827669902912625 171.72815533980582 -0.2845218292821339 0.622335294203664 17.44469517407165 8.969142542988827 1.0797295734909418 0.3501772370559134 1.0 0.730136381958832 0.116076036962074 0.012828563985314 1.5212144559758118e-06 +Sh3 domain binding 15 22 2.7219474751065 0.0064898456549984 6.225728155339806 19.053398058252423 0.1092791230072861 0.6042540048985604 3.326857201432283 4.291792020177848 0.8356987682256717 0.3022221655556643 1.0 1.0 1.0 0.0699377042339779 0.2747427298016877 +Mrna 3 utr binding 15 48 2.672546833213084 0.0075277865874914 16.033980582524272 48.59708737864078 0.0362832452197449 0.6336882607045261 7.2120321981260895 2.351985581765116 0.901256036485658 0.3251065802566649 1.0 1.0 0.5377799970023095 0.5739728683048202 0.0356114340213217 +Dna binding transcription factor activity 15 36 2.658691409602923 0.0078444776919108 11.50242718446602 30.82281553398058 -0.8188750546281067 0.4362036300260354 5.461470865223781 6.923308305861521 0.8546653390190011 0.3163147757174065 1.0 0.9703306074427248 0.9991354356796616 0.9999963035995842 0.999997953345192 +Nuclear receptor coactivator activity 13 25 2.6019632992048023 0.0092691771108412 6.080097087378641 20.868932038834952 -0.4084305492976358 0.6080919107350271 2.992043168249938 3.129456949888674 0.7037972070701939 0.2950093600897926 1.0 1.0 0.4250358756773005 0.1577194377803571 0.0183758279429038 +Microfilament motor activity 6 8 2.5777995973999444 0.0099431644973499 4.254854368932039 8.41747572815534 -0.3879931679821041 0.5033208682101692 2.09265955375398 1.1040461493507936 0.9624876783299348 0.3255338208943681 1.0 0.0937235599037543 0.179062604831997 0.012195883686582 0.0022722304352638 +Rna polymerase ii specific dna binding transcription factor binding 43 98 2.4623999810897965 0.0138010659972165 27.859223300970875 87.64563106796116 -0.690937413393306 0.5245127816149472 10.702263047981718 11.073920002122271 0.7335768841924766 0.3255089446656562 1.0 0.7421235934024417 0.5014549816160067 0.6611153140368126 0.7799656093174502 +Chromatin binding 94 190 2.429384869274241 0.0151244676338135 54.060679611650485 171.85679611650485 -0.7543486110917466 0.5152743640222494 20.94279558503995 16.546679408384886 1.1547176616371866 0.359806819967233 1.0 0.6543872181114005 0.4535352179586751 0.0147831702615367 0.0122178932550884 +Microtubule binding 40 90 2.428869722876024 0.0151459735941126 20.25485436893204 75.27427184466019 -0.1589641223141968 0.6944099688078119 8.720058381838685 9.56302640299361 0.7463760960782003 0.306866020897272 1.0 0.2789713511075724 0.154749287115174 0.4195002915772293 0.0546968940785565 +Microtubule motor activity 10 17 2.330149859162035 0.019798231999061 6.679611650485437 16.466019417475728 -0.3729026878569198 0.59878782969993 3.5457169355503737 2.547854738130346 0.804753592848099 0.3087442838287211 1.0 1.0 0.3776146865857887 0.6971115950162535 0.2049440017843767 +Dna binding transcription factor binding 56 123 2.2711825280974405 0.0231359306598175 35.27669902912621 112.84223300970874 -0.7398054187217702 0.518305774699735 12.768709508076748 13.326441446072891 0.7461781580507518 0.3306494858387695 1.0 0.8374907815202391 0.6966121043933186 0.534809505725178 0.6983402401801234 +Modification dependent protein binding 16 58 2.256210597413756 0.0240574451879134 15.769417475728156 54.16504854368932 -0.3965041215944213 0.6006494389237849 7.38653568118393 8.1524873652378 0.7910532636120504 0.3166915870462006 1.0 0.5266103228678283 0.1847545446978684 0.5092429314984487 0.2018100328112911 +Androgen receptor binding 3 12 2.2555819240578168 0.024096826309738 4.485436893203883 10.03640776699029 -0.907067060465328 0.4043106562697975 2.3342701304977616 1.610383391828647 0.7889958972529045 0.302868883314996 1.0 1.0 0.2108642126213972 0.0201545454959308 0.1093101132411038 +Nucleosome binding 24 39 2.2271868718421124 0.025934787152877 14.970873786407768 33.24757281553398 -1.370722983366063 0.3125683208483105 5.990212584651136 2.4429150444910706 1.2763967120719473 0.3455480236593715 1.0 1.0 1.0 0.0534645551123919 0.0219335059982234 +Basal transcription machinery binding 14 30 2.221231034187537 0.026335317238481 9.966019417475728 26.645631067961165 -0.6371986934557067 0.4822249668731269 5.289099495694056 2.649538399036108 0.9472828516494456 0.3320721996603737 1.0 0.2560754722464486 0.1170412325774002 0.0592065012989733 0.0082674211913202 +Kinase activator activity 6 15 2.208241152368604 0.0272274671070846 5.189320388349515 14.283980582524272 -0.3539998788812653 0.5595906102161438 3.10231396949317 2.7772368190591026 0.7980193695452926 0.2918182504095425 1.0 1.0 0.5094066821340305 0.2590860748448822 0.6888425828692193 +Integrin binding 5 21 2.1994459977066385 0.0278462249994875 6.179611650485437 17.859223300970875 -0.3047919940610424 0.5889748230453251 3.568575338460999 2.9934535983178874 0.818684747476362 0.3137832124263354 1.0 0.3161039234082394 0.5331665625078387 0.040388581958826 0.1722700963890618 +Protein membrane adaptor activity 4 11 2.1799194442537626 0.0292634333370993 3.6092233009708736 9.70873786407767 -0.2128191400839501 0.578166361136985 2.164410361339226 1.215842573812279 0.8154992262040027 0.294410597673656 1.0 0.0802348466038066 0.1543818096433915 0.0076785979426991 0.0010238181908857 +Cyclosporin a binding 4 14 2.178429865891646 0.0293740484014739 5.194174757281553 10.466019417475728 -0.8214842283691128 0.4102118535057494 2.294181125678846 2.053013574598823 0.8958703303479465 0.314577467229102 1.0 1.0 1.0 0.0090496486299172 0.0098879726868235 +Dna secondary structure binding 5 11 2.1604248748586605 0.0307397935167421 3.2184466019417477 10.87135922330097 -0.1978360381474947 0.5285253039842787 2.1790818219962445 1.7010719342013587 0.9128854571916576 0.2949667069435236 1.0 1.0 1.0 0.5811934260914344 0.2421884168027767 +Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor 7 10 2.156089448473849 0.0310766812595015 3.3155339805825244 9.1747572815534 -0.0822659283487201 0.520789618970474 2.835703617469018 1.0397645781526508 0.9371302185048814 0.2942319480110578 1.0 0.0756950383436983 0.1459927402947744 0.0573320310906022 0.0401461367370898 +Amino acid binding 2 12 2.155406662257477 0.0311300254822839 5.058252427184466 12.733009708737864 -0.5130495774586618 0.538768313703938 2.900703773721553 1.616534009474974 0.7937375061308571 0.3141374687541568 1.0 0.1499686155438198 0.2780273254227372 0.559801856438838 0.2160393117631846 +Phosphatidylinositol 3 5 bisphosphate binding 2 6 2.139893271151802 0.0323633930327766 1.9878640776699028 5.395631067961165 -0.1402501362168282 0.5574318023225617 1.458935740904385 1.60589942128011 0.8826420416243104 0.3054144070145976 1.0 1.0 1.0 1.0 0.0798154053066686 +Promoter specific chromatin binding 10 26 2.12869690807593 0.0332793448219836 9.951456310679612 22.825242718446603 -0.8204021161230962 0.441693757161984 4.566931881602575 2.8358905878973273 0.8749745222464043 0.3248257312421662 1.0 0.2183837422916212 0.3898210156705143 0.12361304926291 0.2257163036668415 +Retinoic acid receptor binding 4 8 2.1004721423735417 0.0356873286715484 2.5315533980582523 6.742718446601942 -0.4759865972975309 0.5236979392831508 1.5677188035960552 0.968844967584144 0.8062021234894515 0.2954355126750146 1.0 1.0 0.1951188871774342 0.1003847610205272 0.0892170338783466 +Dynein complex binding 3 6 2.0924845752782275 0.0363951901462062 2.79126213592233 6.543689320388349 -0.1064420873330923 0.5743273343369544 1.5672997492822782 1.031322075719573 0.8650226084801911 0.2946544552154142 1.0 0.0802348466038066 0.0117676307173903 0.0076785979426991 0.0079931710216612 +Single stranded dna binding 16 58 2.077535856163891 0.037752129422778 16.521844660194176 57.383495145631066 -0.3347038319942405 0.6074589437863211 7.691693192662087 4.339200344374205 0.7759217346829941 0.3089540655636336 1.0 0.1043267655807623 0.0973635670841622 0.020109168237517 0.0463253080789513 +Notch binding 2 5 2.0055121034060286 0.0449083281274169 1.3713592233009708 2.849514563106796 -0.1163644067900503 0.6152932408290249 0.9401792315635752 0.9762593347174036 0.8583836460706991 0.3037685716891112 1.0 1.0 1.0 0.0027195691326621 0.0182159139614431 +Catalytic activity acting on a rrna 4 9 2.0052260531844506 0.0449388860346968 4.196601941747573 8.04126213592233 -0.7687137412696428 0.3973203226336884 2.121935393084204 1.8619194499442973 0.933296567982944 0.3020939206963517 1.0 1.0 0.1871299927573601 0.4065747127007614 0.0798154053066686 +Oxidoreductase activity acting on the ch nh group of donors 7 11 2.0039922001920685 0.0450708959492243 3.1601941747572817 10.305825242718448 0.0551009250515943 0.5304967852483793 2.7312588159267728 1.103245454360311 0.9214732780943902 0.2958894860869119 1.0 0.0981765691424607 0.1871299927573601 0.0927037920539492 0.0798154053066686 +Transcription coregulator binding 14 28 1.998757338049414 0.0456346157861502 6.740291262135922 23.75485436893204 -0.3046084245576689 0.5431706114379196 4.011878952648042 3.16313730339845 0.9023447355349592 0.3120304221151172 1.0 1.0 1.0 0.8798456046549319 0.3998794800633873 +Histone deacetylase binding 9 32 1.9891238349912177 0.0466875360924265 9.177184466019416 31.62135922330097 -0.2366699509512635 0.7029030869690139 4.545366128027196 2.995519323354414 0.5749613944201115 0.261783364180922 1.0 0.3491693980885609 0.5773211926082669 0.885714200712916 0.6187452089549611 +Molecular function inhibitor activity 6 10 1.9611633181241723 0.0498599744036067 2.871359223300971 9.580097087378642 -0.0241671823464042 0.5440053162358394 1.747523934052073 1.6839885588394583 0.8722438623760234 0.2818685061983048 1.0 1.0 1.0 0.229635410858896 0.1040239469578102 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6e6484ed670400a8b2822102382a8a26aff9c805 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 1425, + "title": "Average number of proteins per term", + "value": 17.852631578947367 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8c2008a56ce8d4b669389c397dfb6776bbd101aa --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d2dd59a8220b92806ab1e63612161756afc44cf0 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,414 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Rna binding 0.4072147850360137 11.02673461272453 2.839899258795642e-28 1.425000000404685e-15 1.425000000404686e-15 1005 Q9UPT8,P46013,Q9NWH9,P00374,Q14151,Q13049,Q9P2E9,Q92541,Q05048,Q7Z6E9,P62917,P84098,Q9NQ50,P20290,Q66PJ3,Q09666,Q9NZM5,Q6P6C2,Q14966,P48634,P52815,P98175,Q9Y520,Q86V81,P47914,P08579,Q99590,O95104,Q7L2J0,Q08170,O14776,Q8IY81,P62424,P27816,P62750,Q9BY77,P78316,P62081,P62899,Q96CT7,Q9NYF8,Q9H9Y2,Q7L014,Q13428,O43395,P82979,Q13442,Q9Y2W2,Q9BYD3,P42696,Q7Z417,Q8NEF9,Q5QJE6,O75152,Q9BSC4,O60869,Q13573,P51608,Q9Y237,Q9HCD5,Q96E39,Q15637,Q14157,P61604,Q00688,Q5T653,Q9P013,Q8IX12,P12270,Q16576,P16402,Q9Y2W1,Q9H814,Q6PJT7,P53999,Q9BYN8,Q8WUA2,Q15910,P82912,P61254,P19338,P49750,Q99459,Q76FK4,O43818,Q9H501,Q92522,P35579,P46779,Q9C0J8,Q92917,Q5F1R6,Q14498,P55081,P11940,P26583,O00566,O95793,P18615,Q9UMY1,Q969S3,Q14978,Q14692,Q05519,Q6UN15,Q15459,P13667,Q13283,Q9BQ39,Q14331,P62913,P46087,O75347,O75179,Q9H7N4,Q92665,P51858,P78332,P26373,P50914,Q13435,Q96AE4,Q92614,Q8IY67,Q8IWZ3,Q86UP2,O75683,P62314,P62861,Q00341,Q9NXV6,Q9NW13,Q9BVJ6,Q86XP3,Q01844,P16403,P10412,P07305,Q8WXF1,Q5T3I0,Q15056,Q08257,O60841,O75369,P62857,P35580,P39019,Q9Y383,Q86U38,Q15424,Q96PK6,Q12849,P43243,P49756,P55769,Q9BUQ8,Q8NC51,Q8N1G4,Q53F19,P21333,Q5BKZ1,Q14683,Q8WVM0,Q9Y6M1,Q16513,P18583,O15347,Q7Z6Z7,Q9Y3C1,Q9NV06,Q92945,Q13427,Q9BYD2,Q96QC0,Q92888,Q5T8P6,P41214,Q12972,P15311,P50454,P61956,Q02878,Q1ED39,Q9Y3B7,Q99547,Q96GQ7,O15213,P62753,P23588,O95232,Q9UKV3,Q9HAU5,Q13151,P30101,P46777,P58107,Q9Y4C8,O75475,P09874,Q9UHI6,Q9H1E3,Q9BZI7,Q9BRT6,Q92499,P51991,P33240,Q96ST3,Q9GZR2,Q8IXT5,Q6PKG0,P31948,O75150,O95319,P38159,P83731,Q2NL82,Q8NE71,Q9HC36,Q9NZI8,Q15233,P52272,P17480,Q13523,P62841,Q12906,Q15942,Q8IZD4,Q96PU8,P61088,O43290,P25490,P06748,P0DMV9,P23246,Q96T37,Q9ULR0,Q9NPE3,Q9H6F5,Q99848,Q01082,P55036,Q13769,Q14197,Q15149,Q7L2E3,Q96I24,Q8IXM3,Q9UQ35,Q01130,O75494,P05204,P40429,P55072,Q6P1L8,Q9H307,Q9BTC0,Q8WWM7,Q6PK04,Q5T6F2,O60832,P11387,P24928,P53597,P98179,Q99543,Q8NC60,Q8TDD1,Q9NR30,P62805,Q8IVS2,P26599,O75400,O43709,Q14444,Q15050,Q9NTZ6,Q01085,P46778,P08621,P26358,Q9BTD8,Q969X6,Q9BQ61,Q9P015,Q9Y6G9,Q5JTH9,Q13310,P61353,Q12904,O60610,P05455,P46782,P62263,P83881,Q00059,Q02040,Q15287,Q9BWU0,Q9GZR7,Q9Y3Y2,P82673,P22314,O75116,O94992,P11142,P55084,Q96RP9,P35611,P09012,P61247,Q13243,Q96DE0,Q969G3,Q9BRJ2,Q9GZT3,Q9H6R4,Q9Y3D9,Q14697,O95628,P35269,P46776,Q14137,Q14690,Q9NY93,Q96A35,Q9Y2R9,Q9Y6Y8,Q8N9T8,P08238,O43432,Q04837,P36578,Q8WWH5,Q96SB4,Q9BU76,Q9P2N5,Q9Y3I0,Q9UN86,P52758,O75691,P62847,P84103,Q01081,Q13084,Q13823,Q14527,Q9BXP5,Q9Y5B9,Q9UKM9,Q9Y3B4,Q8NEY8,P35221,Q8IY37,P07814,P26038 355 +Calmodulin binding 0.6190947417858802 4.267140942515676 1.979940791962953e-05 0.027820125527662 0.0058217198708468 43 O60869,Q05682,Q7Z406,P35611,Q9UII2,Q07157,P49006,Q13813,O94832,O43795,Q01844,O43815,Q9UM54,Q86VI3,Q15075,P29966,Q01082,P35580,P35579,Q15051,P20020,O00159,Q02952 23 +Protein c terminus binding 0.5398248387032407 4.020209935105467 5.814630254419306e-05 0.0795208139882633 0.0119126974450935 57 Q9NP79,O95104,P11940,P46013,Q12834,P19338,Q14980,Q9Y5K6,Q9UQB8,P55196,P15311,Q9Y366,Q9BV73,Q14676,Q9Y520,P05026,O00159,Q9UN37 18 +Actin filament binding 0.4674191436737434 3.946942917360667 7.91554193539934e-05 0.1066715289736235 0.0125329413977157 77 Q9Y281,Q14331,Q7Z406,P35611,P46940,P35221,P46939,Q66K74,Q92614,Q6WCQ1,Q9ULV4,P49006,O75146,Q9UJU6,P15311,Q13813,Q14247,O94832,Q9Y490,O43795,P59998,Q9UM54,Q86VI3,O00291,Q9UHB6,O75369,P29966,Q01082,P35580,P35579,P55196,Q9H269,Q14315,P47755,O00159,P21333 36 +Transcription corepressor activity 0.5141609858291318 3.7060177756108694 0.0002105435289887 0.2592233509104845 0.0272749571644517 56 Q96ST3,Q9NPF5,Q13573,P51608,Q9HCD5,Q15637,Q8TDD1,Q92785,Q15648,P51858,Q9UER7,Q8IX12,O75446,Q9BQ70,P25685,P80723,Q15910,O14776,Q9H1B7,Q96EB6,Q96L73,Q01130 22 +Transcription coactivator activity 0.4480208120144412 3.633758766233081 0.0002793220356678 0.3283980840711845 0.0310255290079058 94 Q96ST3,Q9NPJ6,Q96GM5,O60885,O60858,O60869,O00233,Q13573,Q92922,Q15648,Q9H7N4,Q13049,Q12824,O00151,O94906,Q9UER7,Q8IX12,P82094,O75528,Q9Y2W1,Q969G3,Q9NVC6,P19474,P53999,O14497,P41223,P12814,Q13503,P06748,O14776,Q13263,Q92925,P17096,Q9UPT9,Q9NPA8,Q9P1Z2,Q96EB6,Q96CT7,Q6ZRS2,O94776,Q96PK6,P26583,Q8TAQ2,P51610,Q9H1E3,P14373,O60828,Q15650 48 +Cytoskeletal motor activity 0.6192086979880936 3.5976444504925937 0.0003211121655815 0.3672363578622738 0.0326846311395461 27 Q13409,P33176,Q9UQE7,Q9UM54,Q13526,Q02241,Q9Y496,Q7Z406,Q14807,Q86Y91,P35580,O00159,P35579,Q8NCM8,O94832,O43795 16 +Chromatin dna binding 0.555115319294929 3.5309764495160914 0.0004140286095726 0.4457353168398467 0.0378102183460957 40 P84243,Q8NC56,P18754,O94842,Q14839,Q92922,Q12824,O95983,P16402,Q969G3,Q8WXI9,Q9Y2U8,Q00839,P16403,P10412,P07305,Q15910,P05114,Q92925,Q7LBC6,Q92522,O94776,Q8TAQ2,P05204,Q9P0M6,O75367,Q9NRF9 27 +Structural constituent of ribosome 0.4515378271889957 3.317303875799725 0.0009089070264132 0.726316096204749 0.0472005714157482 121 P62913,P83731,Q5T653,Q92665,P26373,P61247,P50914,Q9BYD2,P62917,P84098,P62841,P52815,Q9Y3D9,Q02878,Q9Y3B7,Q9UHA3,P47914,P46776,P46778,P62753,Q13405,P82912,P61254,P62424,Q96A35,P62750,Q9Y291,P62273,Q9Y2R9,P62081,P62899,O95182,Q9P015,P62857,P39019,P46777,P46779,P61353,Q8IXM3,P46782,P62263,P83881,P36578,P05387,Q9BYD3,P82650,P40429,P82673,Q6P1L8,P62847 50 +Transcription coregulator activity 0.4743178590493585 3.310764750794615 0.000930413916711 0.7345840349113637 0.0472005714157482 155 Q96ST3,O60858,O00233,Q13049,Q12824,O94906,P82094,Q8IUF8,O75528,Q92804,Q9BQ70,P25685,Q7Z4V5,O14497,P12814,Q9Y2K7,P06748,O14776,Q13263,Q92925,Q9NPA8,Q9H1B7,Q96CT7,Q9NYF8,Q96L73,Q01130,P14373,O60885,O60869,Q13573,P51608,Q9HCD5,Q15637,Q92922,Q8TDD1,Q9UER7,Q8IX12,O75446,Q9Y2W1,P53999,Q15910,P17096,Q96EB6,Q7LBC6,O94776,P26583,Q9Y3E1,Q9NPF5,Q92785,Q15648,Q9H7N4,P51858,Q969G3,Q6IAN0,Q9NVC6,P41223,Q01844,Q96IZ0,Q9P1Z2,Q6ZRS2,Q96PK6,Q9NPJ6,Q96GM5,Q9UKM9,O00151,Q96T23,Q8WUB8,P80723,P06733,P19474,Q00839,Q13503,Q9UPT9,O75475,Q8TAQ2,P51610,Q9H1E3,Q92499,O60828,Q15650 80 +Unfolded protein binding 0.4594591434157872 3.27044752451465 0.0010737746225308 0.7836701455960569 0.0472005714157482 64 P11142,P10809,O76031,Q9NYU2,Q9UHV9,Q9Y4W6,P14625,Q86YB8,P61604,Q8WVJ2,Q9Y4L1,Q9Y266,P31689,P50454,P25685,Q16543,O15212,P07900,P06748,Q8IVD9,P0DMV9,Q9UBS4,P49257,Q96EY1,Q13111,Q99733,P08238,P38646,P50991,Q12931,O75190,P54652,O75494,Q9Y5J6,O15533,P78371,P17987,Q9NUG6,Q13112 39 +Nuclear receptor binding 0.4826379832167257 3.236573492533161 0.0012097407134832 0.8218134212879074 0.0472005714157482 50 Q9UIF9,Q9NPJ6,Q13573,Q8TDD1,Q9NV06,Q15648,O94906,Q9UER7,Q71SY5,P82094,O75528,Q9Y2W1,Q969G3,Q9NVC6,O14497,P41223,Q08752,O43815,P17096,Q96EB6,P32780,O43707,Q96L73,P09874,Q15650 25 +Nucleosomal dna binding 0.5952013724448123 3.1481312001054933 0.0016431792395403 0.9040047246123236 0.0475101499193757 25 P16403,P10412,P07305,P05114,P84243,P16402,P18754,Q8TAQ2,Q969G3,Q8WXI9,Q14839,P05204,O94776,Q92922,Q12824,O75367,O95983,Q92522 18 +Mrna 5 utr binding 0.6294986733788914 3.0993638739970315 0.0019393667439588 0.9371045147574928 0.0477938953923975 22 P62263,P82912,Q9Y6M1,P61254,Q6PKG0,P19338,P62081,P46777,P35580,Q9NZI8 10 +Cis trans isomerase activity 0.5474605163759209 3.0740566361680486 0.0021116933956499 0.9508237641660654 0.0477938953923975 30 Q8WUA2,Q13526,Q96AY3,Q9Y237,Q13356,P30414,Q00688,Q13427,Q6UX04 9 +Cis regulatory region sequence specific dna binding 0.451396659414252 3.033008402406717 0.0024212885823782 0.96839753372343 0.0493829261629184 59 P11387,P38159,P51858,Q9P2D1,Q8IX12,Q9Y2W1,Q12830,Q9NXV6,P53999,Q6P1N0,P25490,Q15910,Q01664,Q9Y467,P17096,Q9P1Z2,Q96EB6,Q99640,O95785,Q96L73,P54727,Q15424,P26583,P17544,P42345,Q9H7B4 26 +Actin binding 0.4292953936537151 2.9779652336542695 0.0029016889672286 0.9840917512557296 0.0523405921303901 121 Q9Y281,P46821,Q9Y2J2,Q14331,Q9P0K7,Q05682,Q7Z406,P35611,P46940,P35221,O00151,Q96HC4,P50402,P46939,P18206,P26038,Q66K74,Q92614,Q6WCQ1,Q9ULV4,P49006,O75146,Q9UJU6,P15311,Q13813,P67936,O94832,Q9Y490,O43795,P59998,Q14247,O43491,Q9UM54,Q96IZ0,Q86VI3,O00291,Q9UHB6,Q9Y6W5,Q8N8S7,Q9NYL9,O75369,Q01082,P29966,P35580,P35579,Q15149,O60610,Q9NR12,P55196,Q9H269,Q14315,P47755,O00159,P21333 54 +Transcription regulator activity 0.464217560477187 2.917603056516601 0.0035273306581116 0.993495961962536 0.0546352846500984 189 Q96ST3,O60858,O00233,Q96EK4,Q13049,Q96KM6,Q12824,O94906,P82094,Q8IUF8,O75528,Q92804,Q9BQ70,P25685,Q7Z4V5,O14497,P12814,Q9Y2K7,P06748,P26367,P25490,P78347,O14776,Q13263,Q92925,Q9NPA8,Q9H1B7,Q96CT7,Q9NYF8,Q96L73,Q01130,P14373,O60885,O60869,Q13573,P51608,Q9HCD5,Q15637,Q92922,Q8TDD1,Q9UER7,Q8IX12,O75446,Q9Y2W1,P53999,Q15910,P17096,Q99459,Q96EB6,Q99640,Q7LBC6,O94776,P17544,P26583,Q00059,Q9Y3E1,Q9NPF5,Q92785,Q15648,Q9H7N4,P51858,Q969G3,Q6IAN0,Q9NVC6,Q9NXV6,P41223,Q01844,Q9Y467,Q96IZ0,Q9P1Z2,Q9H2P0,Q6ZRS2,Q96PK6,Q9H582,Q9NPJ6,Q8WVM0,Q96GM5,Q9UKM9,O95747,O00151,Q96T23,Q8WUB8,P80723,P06733,P19474,Q6P1N0,Q00839,Q13503,Q01664,Q9UPT9,O95785,O75475,Q8TAQ2,P51610,Q9H1E3,Q92499,O60828,Q15650 98 +Mrna binding 0.4552091535381091 2.886630215210315 0.0038939158065851 0.9961499205320647 0.0590301066423813 171 Q13283,O75152,Q9Y6M1,Q6PKG0,P00374,P51608,O75150,O95319,Q9Y3B4,P38159,Q15637,P83731,Q92945,Q9NZI8,P20042,P61247,P26599,Q13243,Q96DE0,P12270,Q96AE4,P52272,Q8IY67,Q12972,Q12906,Q9UNW9,Q8IZD4,Q96PU8,Q00341,Q86V81,Q01085,Q00839,O95232,Q96T37,Q08170,P82912,P61254,P08621,P19338,Q13151,Q9BY77,Q08257,Q9Y2R9,Q07666,P62081,P46777,P35580,Q13769,Q13310,Q9Y383,Q96I24,O43432,P05455,P46782,P62263,P11940,Q96PK6,Q12849,Q9UQ35,Q15287,Q8N684,P49756,Q9BWU0,Q9BZI7,Q9Y3Y2,Q9UN86,P40429,Q8NC51,P52758,P51991,Q53F19,P33240,O00267 73 +Sh3 domain binding 0.5792993411162601 2.7219474751065 0.0064898456549984 0.9999065580036398 0.0680002210174468 22 Q8IZP0,P46108,Q16204,Q9Y5K6,Q96JJ3,O75146,Q96D71,Q9Y6W5,Q07666,Q96PU8,P50570,Q8N8S7,P78536,Q07960,P40818 15 +Mrna 3 utr binding 0.4422661200045347 2.672546833213084 0.0075277865874914 0.9999789303155922 0.0760786942352856 48 P11940,Q9Y6M1,Q6PKG0,O75150,O95319,Q12906,Q13151,Q08257,P62081,Q8NC51,P46777,Q92945,Q13310,Q9NZI8,Q01085 15 +Dna binding transcription factor activity 0.4816478028682415 2.658691409602923 0.0078444776919108 0.999986629444746 0.0787209909223451 36 P17544,Q8WVM0,Q01664,Q9Y467,P51608,Q99459,O95747,Q99640,O95785,Q9H2P0,Q6P1N0,Q9NXV6,Q96KM6,P51858,P25490 15 +Nuclear receptor coactivator activity 0.5287878303242216 2.6019632992048023 0.0092691771108412 0.9999982748121886 0.0886481703553614 25 Q8IX12,Q96PK6,P82094,Q9UPT9,P17096,O75528,Q9Y2W1,Q9NPA8,Q9P1Z2,Q9NVC6,Q15648,Q9H7N4,P41223 13 +Microfilament motor activity 0.7753492555143808 2.5777995973999444 0.0099431644973499 0.9999993458454912 0.0932171671626562 8 Q9UM54,Q7Z406,P35580,O00159,P35579,O94832 6 +Rna polymerase ii specific dna binding transcription factor binding 0.3755825495508571 2.4623999810897965 0.0138010659972165 0.9999999974912726 0.1165647310813459 98 Q96ST3,Q9UIF9,Q9NPJ6,Q9NPF5,Q13573,Q14839,Q8TDD1,P35611,Q15648,Q9NV06,Q12824,Q13049,O94906,Q9UER7,Q71SY5,P82094,O75528,Q9Y2W1,Q969G3,Q04721,P31689,Q13043,Q9NVC6,O14497,P41223,P06748,P42771,P78347,Q08752,O14776,Q14690,P17096,O43815,Q96EB6,P32780,O43707,Q96L73,O94776,P09874,P67870,Q9Y4B6,Q13330,Q15650 43 +Chromatin binding 0.4345857823362767 2.429384869274241 0.0151244676338135 0.9999999996298128 0.1226307521114232 190 Q96ST3,P84243,P18754,Q15059,Q14839,P38159,P54098,Q12824,Q15233,Q9P2D1,P17480,Q9UBU8,O14497,P25490,P06748,P26367,P23246,Q13263,Q92925,Q5VTR2,Q9NPA8,Q13111,Q99733,Q9HCK8,Q9UQR0,Q7L2E3,Q96L73,O14802,P82979,Q5SSJ5,P05204,Q9NRF9,O60885,P11387,P51608,O94842,P24928,Q9HCD5,Q99543,Q92922,P12270,P16402,Q8WXI9,P05114,Q15910,P17096,P26358,Q96EB6,Q7LBC6,Q92522,O94776,Q00059,P18615,P67870,P45973,Q9NRZ9,Q8NC56,O75179,Q15648,O95983,Q969G3,P35269,P16403,P10412,P07305,Q9P1Z2,Q13185,Q9H2P0,Q15424,Q04837,O75717,O95347,Q14683,Q96GM5,Q9H0U9,Q9Y5B9,Q9NTJ3,Q9Y2U8,Q00839,Q9UQE7,Q99496,P32780,Q86U86,Q8N7H5,Q8TAQ2,P51610,Q9H1E3,Q92499,Q9P0M6,O00267,P25440,O75367,Q13112,Q06787 94 +Microtubule binding 0.3653389577799444 2.4288697228760237 0.0151459735941126 0.9999999996411546 0.1226307521114232 90 P46821,Q96SN8,P07197,Q99661,Q9Y3E1,Q9H0H5,Q7Z4H7,Q96Q89,Q9BRK0,Q92974,O15344,Q15398,O15078,P33176,Q9Y448,Q66K74,Q02241,P15311,Q15555,P50570,Q9BSJ2,Q86VS8,Q14008,Q96CW5,Q14203,Q7Z460,P27816,Q14980,Q9BPU6,Q14807,Q9ULW0,P04406,Q9Y496,Q9HC35,Q9UQ16,Q86Y91,Q08379,Q06787,Q8NBT2,Q96ED9 40 +Microtubule motor activity 0.573915401801649 2.330149859162035 0.019798231999061 0.9999999999995788 0.1500663861630957 17 Q13409,Q9UQE7,Q99661,Q02241,Q9Y496,Q14807,Q86Y91,Q96Q89,Q8NCM8,P33176 10 +Dna binding transcription factor binding 0.3860714969596294 2.2711825280974405 0.0231359306598175 0.9999999999999968 0.1714399413791937 123 Q96ST3,Q9UIF9,P45973,Q9NPJ6,Q9NPF5,Q13573,O00233,Q14839,Q8TDD1,P35611,Q15648,Q9NV06,Q13049,Q12824,O94906,Q9UER7,Q71SY5,P82094,O60934,O75528,Q9Y2W1,Q969G3,Q04721,P31689,Q13043,Q6IAN0,Q9NVC6,O14497,P41223,P25490,P06748,P42771,P78347,Q08752,O14776,Q14690,P17096,P19338,O43815,Q9NX58,Q96EB6,P32780,O43707,Q96L73,O94776,P26583,P09874,P51610,Q9UHI6,Q9NUQ3,Q9H1E3,P67870,P21333,Q9Y4B6,Q13330,Q15650 56 +Modification dependent protein binding 0.3916859172547405 2.2562105974137556 0.0240574451879134 0.9999999999999992 0.1734241287443271 58 Q9UER7,P25440,Q04323,O60885,Q15291,Q15059,Q12830,Q99543,Q13185,Q7Z4V5,Q9HCK8,Q92785,Q9UMX0,P55072,P55036,P35573 16 +Androgen receptor binding 0.640284977725273 2.2555819240578168 0.024096826309738 0.9999999999999992 0.1734241287443271 12 Q9UER7,Q13573,Q96L73 3 +Nucleosome binding 0.4299907791435995 2.2271868718421124 0.025934787152877 1.0 0.1831307518667077 39 P84243,O60264,P18754,Q9Y5B9,Q14839,Q92922,Q12824,O95983,P16402,Q969G3,Q8WXI9,O14497,P16403,P10412,P07305,P05114,Q92925,Q99733,Q92522,O94776,Q8TAQ2,Q5SSJ5,P05204,O75367 24 +Basal transcription machinery binding 0.4552602591332957 2.221231034187537 0.026335317238481 1.0 0.1839599365923307 30 O95104,P35269,Q9NQG5,Q96P16,O60885,O60869,Q6P1J9,Q9BRT6,Q14978,Q9H7N4,Q9H7B4,Q92541,Q5BKZ1,Q00839 14 +Kinase activator activity 0.5703479973593344 2.208241152368604 0.0272274671070846 1.0 0.1892641006224178 15 Q9UER7,Q8IZP0,Q13043,P46940,Q9ULW0,Q9NQS7 6 +Integrin binding 0.5221161794538889 2.1994459977066385 0.0278462249994875 1.0 0.1926255855547074 21 P11047,P78536,P35579,P07942,Q9Y490 5 +Protein membrane adaptor activity 0.6418122966580363 2.1799194442537626 0.0292634333370993 1.0 0.1962160191204696 11 Q9Y2J2,P35579,P12270,P49790 4 +Cyclosporin a binding 0.5872298099213152 2.178429865891646 0.0293740484014739 1.0 0.1962160191204696 14 Q13427,Q13356,P30414,Q6UX04 4 +Dna secondary structure binding 0.6384820994804002 2.1604248748586605 0.0307397935167421 1.0 0.2000192043897606 11 P07305,P26583,O15347,P54132,P25490 5 +Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor 0.6510232852581199 2.156089448473849 0.0310766812595015 1.0 0.2007252774310163 10 P11586,Q96C36,P13995,P00374,P30038,P09417,Q6UB35 7 +Amino acid binding 0.6236276866295998 2.1554066622574775 0.0311300254822839 1.0 0.2007252774310163 12 P23378,Q05682 2 +Phosphatidylinositol 3 5 bisphosphate binding 0.7865581594824547 2.139893271151802 0.0323633930327766 1.0 0.2058831922844052 6 O60493,O75146 2 +Promoter specific chromatin binding 0.462980304678711 2.12869690807593 0.0332793448219836 1.0 0.2089121866578271 26 Q9P2D1,Q15910,P26358,P51608,P24928,Q96EB6,Q15648,O75367,P35269,Q00839 10 +Retinoic acid receptor binding 0.6830799636260929 2.1004721423735417 0.0356873286715484 1.0 0.2192001868834333 8 P17096,Q13573,Q15648,Q96L73 4 +Dynein complex binding 0.7762719590888055 2.0924845752782275 0.0363951901462062 1.0 0.2206942381206126 6 Q8TD16,Q14980,P12270 3 +Single stranded dna binding 0.3779894983433554 2.077535856163891 0.037752129422778 1.0 0.2250911482320449 58 Q9GZR2,P26583,Q96AE4,P25205,Q92878,P11387,P53999,Q9H1E3,Q9Y2W2,O95347,P20585,P33991,P54132,Q92541,Q96I24,Q8NFH5 16 +Notch binding 0.821866097892154 2.0055121034060286 0.0449083281274169 1.0 0.2610814094619701 5 Q13573,Q2M2I8 2 +Catalytic activity acting on a rrna 0.6453177145931289 2.0052260531844506 0.0449388860346968 1.0 0.2610814094619701 9 P46087,Q9HC36,Q8WVM0,Q8IY81 4 +Oxidoreductase activity acting on the ch nh group of donors 0.6119764916669399 2.0039922001920685 0.0450708959492243 1.0 0.2610814094619701 11 P11586,Q96C36,P13995,P00374,P30038,P09417,Q6UB35 7 +Transcription coregulator binding 0.4360980826259015 1.998757338049414 0.0456346157861502 1.0 0.2622150302228391 28 P17544,Q71SY5,Q15910,Q00059,P17096,Q9H582,Q14839,Q13185,P51784,O95785,P06733,Q15648,Q9UQB8,P51858 14 +Histone deacetylase binding 0.4268677483227928 1.9891238349912177 0.0466875360924265 1.0 0.2661189557268316 32 P45973,P0DMV9,P23246,Q01664,P09874,Q16513,Q12834,Q9UHI6,O94776 9 +Molecular function inhibitor activity 0.6171032089373062 1.9611633181241723 0.0498599744036067 1.0 0.277989317157257 10 Q9UII2,Q96ST3,P62942,Q9UER7,Q9NWR8,Q9UKS6 6 +Ubiquitin protein transferase regulator activity 0.591417908349618 1.9590429278811952 0.0501077596628614 1.0 0.277989317157257 12 P62081,P46777,P62913,Q12834 4 +Thyroid hormone receptor binding 0.636675464173796 1.9571426654968376 0.050330697422156 1.0 0.277989317157257 9 Q9NPJ6,Q9Y2W1,Q9NVC6,Q15648,Q96L73 5 +Dynactin binding 0.7008996495947468 1.952021656343881 0.050935633512156 1.0 0.278221301723152 7 Q8TD16 1 +Macrolide binding 0.7005331169224138 1.9501883745618895 0.0511536709133093 1.0 0.278221301723152 7 Q96AY3 1 +Fk506 binding 0.7005331169224138 1.9501883745618895 0.0511536709133093 1.0 0.278221301723152 7 Q96AY3 1 +Atp dependent activity acting on dna 0.3680704827947104 1.9470583896490865 0.0515277348400164 1.0 0.2791901982776559 58 Q8WVB6,Q13283,Q9P2D1,Q9UQE7,Q92614,P25205,Q12830,Q96QE3,Q92499,Q9HCK8,P33991,P54132,Q92878 13 +Dynein light intermediate chain binding 0.6532801849608832 1.9413288294757416 0.0522184048132539 1.0 0.2812369432970464 8 Q8TD16,Q86VS8 2 +Nucleoside monophosphate kinase activity 0.6129729128720585 1.937195441518184 0.052721457281823 1.0 0.2824363782954808 10 Q9UIJ7,P27144,Q14168,Q9UDY2 4 +Protein demethylase activity 0.6854732737515432 1.8746122514060053 0.0608460864885098 1.0 0.3107730223875504 7 Q9Y2K7 1 +Four way junction dna binding 0.6401271345971585 1.8703702808485236 0.0614324160071004 1.0 0.3122608612582332 8 O15347,P26583,P25490 3 +Structural molecule activity conferring elasticity 0.9434950385887616 1.8661962654471729 0.0620139113937403 1.0 0.3122608612582332 2 Q09666 1 +Extracellular matrix structural constituent 0.943495038588762 1.8661962654471729 0.0620139113937403 1.0 0.3122608612582332 2 P07942 1 +Microtubule plus end binding 0.5871193810950758 1.8553319624665927 0.0635488366282155 1.0 0.3177441831410776 11 Q9Y448,Q14203,Q99661,Q14980,Q15555,Q14008 6 +5s rrna binding 0.7237353933857689 1.847016984416376 0.0647446787550509 1.0 0.3180146787818192 6 Q9NZM5,P46777,P62913 3 +Rna polymerase binding 0.4184207910645089 1.8449901679207248 0.0650389688711392 1.0 0.3180146787818192 29 O95104,Q9NQG5,O14776,Q9H7N4,Q9H7B4,Q92541,Q5BKZ1 7 +Histone binding 0.3303475741532996 1.8445849393992428 0.0650979394858024 1.0 0.3180146787818192 91 O60885,Q15059,Q99543,Q92922,Q92785,Q9UIG0,Q9UER7,Q96T23,Q16576,Q8WUB8,Q12830,Q7Z4V5,P06748,P16104,Q96EB6,Q13185,Q9HCK8,Q6ZRS2,Q8WXX5,Q15291,P25440,Q13112,Q15906 23 +Sequence specific dna binding 0.3829797690313945 1.836523223917217 0.0662803105774705 1.0 0.3182991272076165 157 Q9UIF9,Q96SN8,P84243,Q9NWH9,Q99661,P10809,P11387,P51608,Q14151,P38159,Q86YP4,O95747,Q96EK4,Q12824,Q96KM6,P51858,O95983,Q9P2D1,Q8IX12,P36776,P17480,Q9Y2W1,Q12830,Q8WXI9,P80723,P06733,Q9NXV6,Q9NYB0,Q92878,P53999,P35251,Q6P1N0,P25490,P06748,Q9Y2K7,P26367,P23246,Q15910,Q00839,Q01664,Q9Y467,P17096,P19338,P26358,Q9HAU5,Q99459,Q9P1Z2,Q96EB6,Q99640,O95785,P54132,Q9H2P0,P20700,Q96L73,O94776,P17544,Q15424,P26583,P54727,Q00059,Q13416,P42345,Q15291,Q9H582,Q9Y3Y2,Q9P0M6,O00411,O75367,Q9H7B4 69 +Tubulin binding 0.3530536373591185 1.831331249635412 0.0670511160619515 1.0 0.31849280129427 116 P46821,Q96SN8,P07197,Q99661,Q9Y3E1,Q9H0H5,O75347,Q7Z4H7,Q96Q89,Q9BRK0,Q92974,O15344,Q15398,P50402,O15078,P33176,Q9Y448,P12270,Q66K74,Q02241,P16949,P15311,Q15555,P50570,Q9BSJ2,O14737,Q86VS8,Q14008,Q96CW5,Q14203,Q9UQE7,Q7Z460,P27816,Q14980,Q9BPU6,Q14807,Q9ULW0,Q9H2P0,P04406,Q9Y496,Q9HC35,Q9UQ16,Q86Y91,Q08379,Q06787,Q8NBT2,Q96ED9 47 +Dna binding transcription repressor activity 0.5936531264551059 1.824455192670137 0.0680832844471237 1.0 0.3201936644790473 10 P51858,P06733,Q96EK4,Q96KM6,Q6P1N0,P25490 6 +Nadph binding 0.7134719245412512 1.7984504097888987 0.0721056604696044 1.0 0.329328737721751 6 Q08257,P00374 2 +Growth factor activity 0.6265011824103648 1.7964277480186812 0.0724265140994822 1.0 0.3297373245743199 8 Q9Y3E1 1 +Phosphoserine residue binding 0.7121104327674681 1.7919938756899845 0.0731339470408702 1.0 0.3318976895963062 6 O95104,Q92541 2 +Rna polymerase ii c terminal domain binding 0.7086870857343631 1.775745366057185 0.075774896324757 1.0 0.3353320560859889 6 O95104,Q92541,Q9H7N4 3 +Structural molecule activity 0.4050246910271217 1.7703103479677975 0.0766754551816699 1.0 0.3353320560859889 229 P83731,P49790,P07942,P62917,P84098,Q09666,P62841,P52815,P55735,P47914,P62424,P27816,Q14980,P62750,P62081,P62899,O95182,Q01082,Q15149,Q8IXM3,Q9BYD3,P40429,Q6P1L8,Q9H307,Q96EE3,Q5T653,P12270,Q9Y5K6,Q9UHA3,Q7Z3B4,P35658,P46778,Q9Y490,P82912,P61254,P17096,P11047,Q9P015,P46779,P61353,Q8NFH5,P46782,P62263,P83881,P82650,P82673,O75116,P23258,P46821,P07197,Q9Y2J2,P62913,Q92665,P26373,P18206,P61247,P50914,P09496,Q9Y3D9,Q13813,P46776,Q13405,O43491,Q96A35,Q9Y291,Q9Y2R9,P62857,Q16527,P39019,O94979,P36578,P43243,P62847,Q13084,Q9BVA1,P35221,O60504,Q9BYD2,Q02878,Q9Y3B7,P62753,P59998,P62273,O00291,P46777,P58107,P05387,Q9BZI7 88 +Vitamin d receptor binding 0.661889054900247 1.755316836675767 0.0792051281533503 1.0 0.3424702927984647 7 Q9Y2W1,Q9NVC6,Q15648,Q13573 4 +Vinculin binding 0.7017108167770534 1.7425718909563708 0.0814084235921159 1.0 0.3468831959735825 6 Q9Y3I0,P35221,O60504,P46939,Q9Y490 5 +Protein kinase c binding 0.5006169475513198 1.7238482253500742 0.0847352460487187 1.0 0.3540989021097483 15 P21333,Q96HC4,P14314,P29966 4 +Estrogen receptor binding 0.4919999981739978 1.6982529807454545 0.0894600249075279 1.0 0.3585608513250886 16 O43815,P09874,Q9NV06,Q15648,Q96L73 5 +Beta catenin binding 0.4737175815213953 1.6487370613794408 0.0992015139691577 1.0 0.3841362972990484 18 Q9Y5K6,P19022,Q9HCK8,O14745,P18206 5 +Structural constituent of cytoskeleton 0.3857973132765295 1.6421970264270458 0.1005491787519092 1.0 0.3855110622400623 35 P59998,P07197,Q96CW5,Q01082,Q9BVA1,Q9Y2J2,Q9Y5K6,Q15149,O00291,Q13813,O60504,P26038,P23258,Q9Y490 14 +P53 binding 0.4444852267743755 1.6387260863117576 0.1012703186848003 1.0 0.3858561607642791 22 Q9UER7,O60885,Q9NZM5,Q9HCK8,Q9NXV6,P54132 6 +Structural constituent of synapse 0.5960795140806124 1.629906467566956 0.1031212665352052 1.0 0.3903815912516865 8 Q16352,Q9UQ16,Q8IUD2,P56545,Q15334,P12814,P07196 7 +7sk snrna binding 0.6774367476990517 1.6265431966179926 0.103834151914945 1.0 0.3914382711079277 6 Q7L2J0,Q9NR30,O94992 3 +Heat shock protein binding 0.3467435347111991 1.615428704838417 0.1062178881920887 1.0 0.3947330745560977 53 Q9UER7,P0DMV9,Q8WXX5,P12270,Q00059,Q96GD0,P31948,P55011,O75190,P54652,Q99543,P31689,P25685,Q16543,Q96EY1,Q15785,O75937,Q9NXW2 18 +Phosphatidylinositol 3 phosphate binding 0.5930308036913792 1.6131212553061571 0.106718166841961 1.0 0.3947330745560977 8 O60493,Q9NS86 2 +Myosin binding 0.5190878205577104 1.6096320890882014 0.1074781985458006 1.0 0.3947330745560977 13 Q13049,Q05682,O14745 3 +Signaling adaptor activity 0.4611137654245792 1.6019571789501588 0.1091650789414475 1.0 0.3958590907332399 19 Q12802,Q8IZP0,O60271,Q07666,Q9UN86,P46940,Q6SZW1,Q7Z434,Q13112 9 +Rna polymerase ii c terminal domain phosphoserine binding 0.9192565981278592 1.6019178790893576 0.1091737702864303 1.0 0.3958590907332399 3 Q92541 1 +Sequence specific mrna binding 0.590690180233383 1.6002238564309144 0.109548931607629 1.0 0.396211237413379 8 P00374 1 +Histone methyltransferase binding 0.6705810210774625 1.5936187844558791 0.111021444583045 1.0 0.4000663785701576 6 O95785,Q13185 2 +Isocitrate dehydrogenase activity 0.7275148223035852 1.5886576497296985 0.1121377051227752 1.0 0.4014980648240067 5 P48735 1 +Lysine acetylated histone binding 0.5417825954810371 1.5800003713881383 0.1141067814240841 1.0 0.4044829938540296 11 Q15059,Q92785,P25440 3 +Pre mrna binding 0.4506628255796505 1.571096644030824 0.1161602020220633 1.0 0.410473803175 20 P09651,P26599,Q9Y580,Q01130,Q9NW64,O95319,Q15637,Q01081,P22626,Q13247,Q00839 11 +Gamma tubulin binding 0.6242648395234098 1.5629278242990563 0.1180695722384244 1.0 0.410473803175 7 Q96CW5,Q96SN8,Q9H0H5,O00571,Q9BSJ2 5 +Transcription coactivator binding 0.6237781680323777 1.5604250822243246 0.1186594613602962 1.0 0.410473803175 7 P17544,Q00059,Q15648 3 +Methylated histone binding 0.386665140817289 1.5482597929685589 0.1215597606232585 1.0 0.4174039973208276 30 Q7Z4V5,Q12830,Q92785,Q9HCK8 4 +U1 snrna binding 0.6200522230430133 1.5412539387469464 0.1232549945005077 1.0 0.421195125091663 7 P08579,P08621 2 +Intermediate filament binding 0.7706934817098126 1.535628488153562 0.1246295230735028 1.0 0.4238593565148962 4 P48681,P58107 2 +Oxidized dna binding 0.6184202586498633 1.532851445450803 0.1253124615717489 1.0 0.4247811547102973 7 P20585,P18887 2 +Map kinase scaffold activity 0.7637782709833233 1.506445861501332 0.1319527551117336 1.0 0.4292983471100924 4 Q12802,O60271 2 +Adenylate kinase activity 0.7632509221246332 1.5042190734689531 0.1325249682103506 1.0 0.4301778580859901 4 P27144,Q9UIJ7 2 +Core promoter sequence specific dna binding 0.4646946189804556 1.4999908655237306 0.1336167687047345 1.0 0.4317548648622373 16 P06748,Q9UIF9,Q15910,P84243,P17480,Q12824,O75367 7 +Ubiquitin protein transferase inhibitor activity 0.5718344794869827 1.4960204423566712 0.1346483281430779 1.0 0.4329575329506226 8 P62081,P46777,P62913 3 +Actinin binding 0.7034482758620583 1.480555024065545 0.1387251878831987 1.0 0.4373851360286714 5 Q96HC4,O00151,Q9NR12,Q16527 4 +Glutamate receptor binding 0.5351961197209044 1.4780104637797329 0.1394049775168588 1.0 0.4373851360286714 10 Q9UQ16,O00291,P0DP25,Q15334,O14745,O75955 6 +Rna 2 o methyltransferase activity 0.8517089305402634 1.4778185834566544 0.1394563429192192 1.0 0.4373851360286714 2 Q8IY81 1 +Tat protein binding 0.7025715192457329 1.476607645952713 0.1397808409805154 1.0 0.4373851360286714 5 P06748,Q13049 2 +Polyubiquitin modification dependent protein binding 0.4656254648647505 1.474950001208862 0.140225986063855 1.0 0.4373851360286714 15 Q04323,P55072,Q9UMX0,P55036,P35573 5 +Rna polymerase core enzyme binding 0.4316319505475746 1.472167112639139 0.1409757559463411 1.0 0.4373851360286714 21 O95104,Q9H7N4,Q9H7B4,Q92541,Q5BKZ1 5 +Cadherin binding 0.3846873586696203 1.4668431111687144 0.1424187390296867 1.0 0.4373851360286714 215 Q8WWM7,Q5T6F2,P04083,Q8IZP0,Q9UQN3,Q16513,Q6PKG0,Q9NUQ8,Q9UHD8,Q05682,P83731,P35611,P46940,A0FGR8,Q96HC4,P50402,Q9UNF0,P40818,P18206,Q13177,P50914,P33176,Q07157,Q6WCQ1,Q09666,Q86UP2,Q9Y5K6,P15311,P25685,P19022,Q02878,Q00341,Q13813,P47914,P43487,Q9NZZ3,Q6P1N0,Q14008,Q14247,O43795,Q9Y490,Q9H444,P62424,Q9H4M9,Q99961,P62750,Q15056,Q9UHB6,Q9Y6W5,O75369,Q9NYL9,Q01082,O75874,O60664,Q92522,Q07960,Q15149,P35579,P08238,Q15019,Q14677,Q9UDY2,Q9H223,O96013,P51610,P55196,Q13112,Q9H2G2,Q8NC51,P53990,Q9UQB8,Q08379,P21333,P11142 74 +Protein disaggregase activity 0.7533952708627827 1.462570979276082 0.1435848090398246 1.0 0.4377209796857643 4 P0DMV9,Q9UN37 2 +Dna binding transcription activator activity 0.4631592036667137 1.4573205544951715 0.1450279155804725 1.0 0.4382352496108288 15 Q99459,Q01664,Q9NXV6,Q9Y467 4 +Dna binding bending 0.6976753980402399 1.454554236689478 0.1457927080820682 1.0 0.4382352496108288 5 O15347,P26583 2 +U3 snorna binding 0.5307667005808754 1.4515182456067766 0.1466356053758859 1.0 0.4382352496108288 10 O43818,Q14692,P55769 3 +Smad binding 0.457116665381875 1.4447249709891616 0.1485351529835099 1.0 0.4382352496108288 16 P62942,Q9H6Z4,P09874,Q13573,P25490,Q9Y4E8,Q9UNE7,P26367,P17844 9 +Single stranded dna endodeoxyribonuclease activity 0.7477747228647654 1.4387957007062415 0.1502084148664852 1.0 0.4382352496108288 4 Q92878,P18887 2 +Nadp binding 0.4339989960396072 1.43817683685718 0.1503838856559265 1.0 0.4382352496108288 20 Q08257,O75874,P00374,P09417 4 +Phosphoprotein binding 0.3951923223150212 1.4205913547996076 0.1554355932324609 1.0 0.4474661017298117 25 O95104,P14314,Q13526,Q9Y2W1,Q92541 5 +Transcription factor binding 0.3618789398570754 1.4163036938732456 0.156686606802185 1.0 0.4494906515352068 165 Q96ST3,Q9UIF9,P45973,Q9NPJ6,O60869,Q13573,O00233,Q9NPF5,Q14839,P51784,Q8TDD1,P35611,Q15648,Q9NV06,Q13049,Q12824,O15160,O94906,P51858,Q9UER7,Q71SY5,P82094,O60934,O75528,Q9Y2W1,Q969G3,Q04721,P31689,Q13043,Q6IAN0,Q9NVC6,P06733,P35269,O14497,P41223,Q00839,P25490,P06748,P42771,P26367,P78347,Q08752,O14776,Q15910,P17096,P19338,Q14690,O43815,Q9NX58,Q96EB6,Q13185,O95785,P32780,Q96L73,O43707,O94776,P17544,P26583,P38935,Q00059,P09874,P42345,P51610,Q9UHI6,Q9H582,Q9NUQ3,Q9H1E3,Q14978,P67870,Q9UQB8,P21333,Q9Y4B6,Q13330,Q15650 74 +Protein serine threonine kinase activator activity 0.5954787565593338 1.4144302278396703 0.1572356199913902 1.0 0.4494906515352068 7 Q13043,P0DP25,Q9NQS7,P46940 4 +Armadillo repeat domain binding 0.7402187001403308 1.4068108893194713 0.1594834727232261 1.0 0.4545278972611946 4 Q9HCK8,O43815 2 +Snrnp binding 0.6275125565171951 1.3855971790746573 0.1658699400932159 1.0 0.4689775091921285 6 P08579,P62314 2 +Kinetochore binding 0.6226346840611641 1.3619451209689974 0.1732152050031805 1.0 0.4839836610382986 6 Q9Y6D9 1 +Rrna binding 0.3355374333987772 1.3603874869417338 0.1737073361206107 1.0 0.4844089118823293 47 Q9H9Y2,P46782,P62917,P62263,P82912,Q9NY93,Q9NZM5,P62750,Q15050,P62913,Q9Y3B7,P46777,Q9NR30 13 +Nad binding 0.3688052682623405 1.3569707573523102 0.1747905023148752 1.0 0.4852643264729805 29 P09874,O43837,P09417,Q08257,O75874,P48735 6 +Phosphatidylinositol 5 phosphate binding 0.8560523935425884 1.356199522575453 0.1750356938997277 1.0 0.4852643264729805 3 Q9NS86 1 +Ubiquitin like protein conjugating enzyme binding 0.4469001130689148 1.3409705697364709 0.1799300080464645 1.0 0.4959386101860966 15 Q9UBW7 1 +Rna polymerase ii general transcription initiation factor binding 0.5278095301414022 1.3373350109304132 0.1811133076552717 1.0 0.4970903003317717 9 O60869,Q14978,P35269 3 +Rna methyltransferase activity 0.4013407206628437 1.3364741162977798 0.1813943552087868 1.0 0.4970903003317717 23 Q7L2J0,Q8WVM0,Q8IY81,P46087,Q9HC36,Q96FX7 6 +Spectrin binding 0.5786257420855396 1.3271857392797408 0.184447248576498 1.0 0.5006425318504948 7 P35611,Q9Y496,O43491 3 +Regulatory rna binding 0.4438706055741224 1.3192826263174164 0.1870746438841437 1.0 0.5049147146806245 15 P09651,Q9NY93,P43243,P51608,P98175,Q9NR30,Q06787 7 +Dna polymerase activity 0.5086929963751562 1.3192540648827344 0.1870841890185051 1.0 0.5049147146806245 10 P54098,Q9NRF9 2 +Protein phosphorylated amino acid binding 0.4744939060130554 1.3164280624400078 0.1880304087208553 1.0 0.5059582750094512 13 O95104,Q92541 2 +Disordered domain specific binding 0.4355757960805229 1.2874335659124987 0.1979432112418857 1.0 0.5223501407771984 16 Q9Y3C6,Q14980,P54652,P15311,P08238,P0DP25,P04406 7 +Peroxisome proliferator activated receptor binding 0.8040242557883202 1.275155974473409 0.2022540405493398 1.0 0.527187930009618 2 Q15648 1 +Clathrin light chain binding 0.8342637860287269 1.2714504095326136 0.2035684588636193 1.0 0.527187930009618 3 O75146 1 +Ankyrin binding 0.8340226082161555 1.2705131665662854 0.2039018958389924 1.0 0.527187930009618 3 Q14315,Q01082 2 +Demethylase activity 0.5005066641963642 1.2701615994973632 0.2040270730746041 1.0 0.527187930009618 10 Q6P6C2,Q9Y2K7 2 +2 oxoglutarate dependent dioxygenase activity 0.4331762095787733 1.269918501012914 0.2041136622170047 1.0 0.527187930009618 16 Q6P6C2,Q9Y2K7 2 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides 0.7078454514672866 1.2696314083832323 0.2042159560458309 1.0 0.527187930009618 4 Q05682 1 +Kinase regulator activity 0.3275529305262372 1.2639771758288096 0.2062382192556406 1.0 0.5276646948772233 47 Q8IZP0,P46940,P11802,Q13177,Q9UER7,Q9H9T3,Q92616,Q13043,Q16543,Q9NQS7,P06748,P42771,Q9ULW0,P08238,P0DP25,Q13217,P60983,Q9ULH0,P67870,O75367,O94992,Q9NVD7 22 +Catalytic activity acting on dna 0.2961405649382103 1.250879217038135 0.2109785474245091 1.0 0.5276646948772233 93 Q8WVB6,Q13283,Q14249,O60832,P11387,P54098,P18887,P39748,Q9P2D1,Q92614,P25205,Q12830,Q96QE3,Q92878,Q9UQE7,Q9HCK8,P33991,P54132,P49916,Q92499,Q9NRF9 21 +Dynein light chain binding 0.828814939879551 1.2502820656470888 0.2111965274327074 1.0 0.5276646948772233 3 Q13409 1 +Alpha actinin binding 0.7032542746828319 1.250179103055973 0.2112341286385359 1.0 0.5276646948772233 4 Q9NR12,Q96HC4,O00151 3 +Muscle alpha actinin binding 0.7032542746828319 1.250179103055973 0.2112341286385359 1.0 0.5276646948772233 4 Q9NR12,Q96HC4,O00151 3 +Microtubule minus end binding 0.5622859329654011 1.2425357227804965 0.2140389687717829 1.0 0.5295559991509049 7 O15078 1 +Cytoskeletal protein binding 0.3751793769291392 1.2425000850460275 0.214052109130471 1.0 0.5295559991509049 282 Q8TD16,O60271,Q05682,Q7Z406,Q9BRK0,Q13049,Q92974,Q9UNF0,O15078,Q9BSJ2,O14737,O94832,P27816,Q14980,Q9BPU6,Q9UHB6,Q01082,Q15149,Q9NR12,P55196,Q14315,O00159,Q96ED9,Q9Y281,Q13464,Q8IZP0,Q9P0K7,Q96HC4,P12270,Q02241,Q5JTV8,Q86VS8,O43795,Q9Y490,Q14807,Q9NYL9,Q9ULW0,P35579,O60610,Q9Y496,P47755,O75116,P46821,P07197,Q9Y3E1,Q9Y2J2,Q9H0H5,Q14331,O75347,P35611,Q7Z4H7,P46940,O15344,P50402,P46939,P18206,Q9Y448,Q92614,Q86UP2,Q9ULV4,P16949,Q15555,Q13813,O14745,O43491,Q9UM54,Q96IZ0,Q9Y6W5,Q8N8S7,O75369,P29966,P35580,P08238,Q16527,Q9H2P0,P04406,P54652,Q9H269,Q9Y3I0,Q9UKS6,Q86Y91,Q08379,P21333,Q8NBT2,Q99661,P35221,O00151,O60504,Q15398,P26038,P33176,Q13561,Q66K74,Q6WCQ1,Q13526,P49006,O75146,Q9UJU6,P15311,P50570,Q14008,Q14247,P67936,Q00839,P59998,Q96CW5,Q14203,Q9UQE7,Q86VI3,O00291,Q9HC35 111 +K48 linked polyubiquitin modification dependent protein binding 0.6498619149662394 1.2386994935857785 0.2154568063188002 1.0 0.5303880007214631 5 Q04323,P55072 2 +Cell adhesion molecule binding 0.3758260291485241 1.236481221986096 0.2162797414868678 1.0 0.5303880007214631 243 Q8WWM7,Q9BY67,Q5T6F2,P04083,Q8IZP0,Q9UQN3,Q16513,Q6PKG0,Q9NUQ8,Q9UHD8,P10586,Q05682,P83731,P35611,P46940,A0FGR8,Q96HC4,P50402,Q9UNF0,P07942,P40818,P46939,P18206,P50914,Q07157,P33176,Q6WCQ1,Q09666,Q86UP2,Q9Y5K6,P15311,P25685,P19022,Q02878,Q00341,Q13813,P47914,P43487,Q9NZZ3,Q6P1N0,Q14008,Q14247,O43795,Q9Y490,Q9H444,P62424,Q13308,Q9H4M9,P62750,P11047,Q15056,Q9UHB6,O75369,Q9NYL9,Q01082,O75874,O60664,Q92522,Q07960,Q15149,P35579,Q15019,Q14677,Q9UDY2,O96013,P51610,P55196,Q13112,Q9H2G2,Q8NC51,P53990,P78536,Q9UQB8,Q08379,P21333,P11142 76 +Mirna binding 0.4756247877535136 1.2316070883163863 0.218095891814666 1.0 0.5303880007214631 12 P09651,Q9NY93,P43243,P98175,Q9NR30,Q06787 6 +Mrna 3 utr au rich region binding 0.4752735725883133 1.2293800283827432 0.2189293546680772 1.0 0.5303880007214631 12 Q92945,Q13151,Q12906 3 +Helicase activity 0.292774933167131 1.2286498107356842 0.2192031312717592 1.0 0.5303880007214631 91 Q8WVB6,Q13283,P13984,Q9BQ39,Q8TDD1,Q9P2D1,P25205,Q96GQ7,Q92878,Q86XP3,Q9HCK8,P33991,P54132,Q7L2E3,Q6ZRS2,Q7L014,Q9UHI6,Q9BUQ8,Q92499 19 +Translation activator activity 0.8225969456393973 1.2261443870407815 0.2201443448653224 1.0 0.5303880007214631 3 P11940 1 +Damaged dna binding 0.3498606424696578 1.2256148507102302 0.2203436466155131 1.0 0.5303880007214631 33 P16104,P26583,O60934,P20585,P18887,P39748,Q96T60 7 +Transcription regulator inhibitor activity 0.695321609556391 1.2165848695845982 0.2237622023390812 1.0 0.5361850759666312 4 Q96ST3,Q9UER7 2 +Dna helicase activity 0.3343934350184505 1.2113431799276306 0.2257639062292242 1.0 0.5367772348541331 41 Q8WVB6,Q13283,Q9P2D1,P25205,Q9HCK8,P33991,P54132,Q92878 8 +Long chain fatty acid transporter activity 0.6932355639646486 1.2077549758810815 0.2271415246435384 1.0 0.5367772348541331 4 O14678 1 +Protein serine threonine tyrosine kinase activity 0.2902728822080136 1.205253875194471 0.2281053098841146 1.0 0.5381623618954691 75 Q13464,P11274,Q9NWH9,Q16513,P51956,O00311,P42345,Q2M2I8,Q13523,O96013,O95747,Q13043,Q99640,Q9H2G2,O75116,P11802,Q9UIG0,Q9Y5S2 18 +Dna directed dna polymerase activity 0.5187147918979552 1.2008740341206512 0.229800067963541 1.0 0.5412646228893322 8 Q9NRF9 1 +S acyltransferase activity 0.5884609069030071 1.1961269239053207 0.2316470323426362 1.0 0.5447145562512486 6 Q8IVS2,Q8IUH4 2 +Sumo transferase activity 0.688909320549896 1.1894499184280038 0.2342626674240908 1.0 0.5499576624041671 4 P14373,P49792 2 +Channel regulator activity 0.4241289579768029 1.1781351768477764 0.2387427202172303 1.0 0.5540853034357544 15 Q9UKS6,Q9NWR8,O14745 3 +Ubiquitin binding 0.3491382218197237 1.1745413201802717 0.2401782714688876 1.0 0.5550390228000942 30 P54727,Q5TDH0,Q9H1I8,Q04323,Q9UNZ2,O14964,P61088,Q13049,O95071 9 +Protein tyrosine kinase activator activity 0.7797684674752221 1.1725499431351265 0.2409763329957308 1.0 0.5556493115192823 2 Q8IZP0 1 +Box h aca snorna binding 0.63313159265887 1.1632174009742655 0.2447413082243197 1.0 0.5589044298391916 5 Q9NPE3,Q14978 2 +Dynein heavy chain binding 0.6800622079572229 1.1520535381000685 0.2492990738366627 1.0 0.5638907622495942 4 Q13409,O43237 2 +Protein macromolecule adaptor activity 0.3012469384906904 1.1487554433213594 0.250656836860057 1.0 0.5642748697086591 105 P45973,Q8IZP0,Q8TD16,Q9Y2J2,O60271,Q86YP4,P49790,P46940,Q6SZW1,O43752,Q12802,O75147,P12270,O75146,Q92878,O14745,P51809,P59998,O00291,O95721,P05026,Q7Z434,P35579,Q13428,Q9UDY2,P51610,Q9UHI6,Q13112,Q14978,Q9UQB8,P11142 31 +Toxic substance binding 0.7728776185226256 1.143519171312391 0.2528230995899796 1.0 0.566735341137056 2 Q9H814 1 +Structural constituent of nuclear pore 0.3961316764171886 1.1362093596032488 0.2558689543078571 1.0 0.5688352236256704 20 P35658,P12270,P49790 3 +Cadherin binding involved in cell cell adhesion 0.4694235496853802 1.1347923642887994 0.2564623262958743 1.0 0.5688352236256704 11 P04083,O96013,Q9NYL9,Q9UQB8,Q96HC4 5 +Rna polymerase i transcription regulatory region sequence specific dna binding 0.6738175493171632 1.1256951114290452 0.2602945936826093 1.0 0.5741792507704617 4 P17480,Q9UIF9 2 +Poly purine tract binding 0.4162680158857041 1.1221308712175682 0.2618067996455735 1.0 0.5757325455168862 15 P11940,Q07666,Q92499,Q13310,Q6PJT7,Q00839 6 +R smad binding 0.6231724137931007 1.1183785990117738 0.2634053305763248 1.0 0.577552395711188 5 P17844,Q9H6Z4,P09874,P26367 4 +Poly a binding 0.4660049056187031 1.1138160127387873 0.2653581259875184 1.0 0.5790740115347837 11 P11940,Q92499,Q13310,Q6PJT7,Q00839 5 +Alpha catenin binding 0.6697187115122486 1.1084144162634362 0.2676828817288892 1.0 0.5832539854184513 4 P19022 1 +Proteasome activating activity 0.5689845474613647 1.1018328259145551 0.2705343565693741 1.0 0.5880926942637048 6 P35998,P62195,P17980,P62333,P62191 5 +Aspartic type endopeptidase inhibitor activity 0.7626791620727997 1.100680002253786 0.2710359527542798 1.0 0.5880926942637048 2 Q13464 1 +C3hc4 type ring finger domain binding 0.7899090157154656 1.0997468678279332 0.2714424280375169 1.0 0.5880926942637048 3 P0DMV9,P31689 2 +Copper ion binding 0.4982782859887243 1.0875725219582004 0.2767838667280307 1.0 0.5940015212160297 8 O60888,O75592 2 +Cytoskeletal anchor activity 0.4807362295055035 1.066319686512333 0.2862791532345767 1.0 0.6079698857813292 9 Q9Y2J2,Q8TD16,Q9UQB8 3 +Rna strand annealing activity 0.6102068965516926 1.0601694816811462 0.289067502382214 1.0 0.6102536161402297 5 P23588,O00571,Q15056,Q06787 4 +Retinoid x receptor binding 0.7788806175902933 1.0573678794672832 0.2903437249555236 1.0 0.6120411361858301 3 P17096,Q96L73 2 +Hsp70 protein binding 0.4031555737600365 1.0518047440034055 0.2928891420622359 1.0 0.6143349392452994 16 Q99543,Q96EY1,P25685,O75937,Q9NXW2 5 +Endodeoxyribonuclease activity 0.4554421941527771 1.0491804685216153 0.2940950661732906 1.0 0.6143349392452994 11 Q92878,P18887,P39748 3 +Protein kinase activity 0.2903358160114708 1.0489729580794809 0.2941905645580935 1.0 0.6143349392452994 100 Q13464,Q9NWH9,Q16513,O60885,P11387,O95747,Q05682,P11802,Q9UIG0,Q12802,Q13523,Q13043,Q9Y5S2,P11274,Q13308,Q99640,P51956,O00311,P42345,Q2M2I8,O96013,Q9H2G2,P67870,P25440,O75116 25 +Isomerase activity 0.2762575696935997 1.0473764771703604 0.2949259763420597 1.0 0.6143349392452994 77 P13667,Q9Y3C6,O60832,P11387,Q13572,Q96AY3,Q9Y237,Q9H2H8,Q00688,Q13427,Q6UX04,P18669,Q13526,Q8WUA2,Q8NBS9,P30101,Q13356,P30414,Q13630 19 +Chromo shadow domain binding 0.6045757587657759 1.03496328386435 0.3006860583384294 1.0 0.6191873311159855 5 Q13111,Q14739 2 +Structural constituent of postsynapse 0.604137931034475 1.0330056782132628 0.3016012413919371 1.0 0.6199370800881779 5 Q16352,Q15334,P12814,Q9UQ16 4 +Calcium channel inhibitor activity 0.7711607389026726 1.0278091870255346 0.3040395938873628 1.0 0.6233905342294849 3 Q9UKS6,Q9NWR8 2 +1 alkyl 2 acetylglycerophosphocholine esterase activity 0.7436604189636119 1.0212874114013737 0.3071182888709756 1.0 0.6278960712211481 2 P68402 1 +Annealing activity 0.4569693021481629 1.0102601714584325 0.3123706577027203 1.0 0.6317048219966099 10 P23588,P51114,Q15056,O00571,P54132,Q06787,P04637 7 +Cyclin dependent protein serine threonine kinase regulator activity 0.6461665747379992 1.0095333219004194 0.3127189292379273 1.0 0.6317048219966099 4 P42771,P11802,O94992 3 +Dynein intermediate chain binding 0.4690847907211533 0.9998012126087338 0.3174067188829124 1.0 0.6347426908077902 9 Q86VS8 1 +Bhlh transcription factor binding 0.6435243417512233 0.998494777598093 0.3180394956047454 1.0 0.6347426908077902 4 O00233 1 +Nitric oxide synthase binding 0.6409266409266403 0.9876551126216006 0.3233215850397881 1.0 0.6407972999745454 4 P0DP25,P50570,Q9UQ16 3 +Single stranded rna binding 0.3119833684005835 0.9777447537106132 0.3282005811929851 1.0 0.6459749008287345 42 Q96DH6,Q9UNP9,Q9H7N4,P26599,P36776,Q12906,Q6PJT7,Q00839,P09651,P23588,P07910,Q9HC52,Q9Y580,Q15056,Q07666,O00571,Q13310,P05455,Q01780,P11940,P38935,Q92499,Q06787 23 +Double stranded rna binding 0.320308109271586 0.9571800295312244 0.3384763950937803 1.0 0.6607244698748451 35 P23588,Q9NY93,O95793,P10809,P26038,Q15056,Q12906,Q92499,P08238,P12814,Q9NR30,Q9NZI8,Q7L2E3,Q00839 14 +Protein kinase a regulatory subunit binding 0.4594520715413804 0.9451439230951472 0.3445854038159668 1.0 0.6657606107649201 9 Q9H3P7,Q9Y6W5,O43164,P15311 4 +Beta tubulin binding 0.3753528704811221 0.9364176767722162 0.3490581801912591 1.0 0.6710181830743072 19 Q9UQE7,Q9H0H5,Q9HC35,O75347,Q9H2P0 5 +S100 protein binding 0.4695710911385198 0.9299480387964296 0.3523979886301334 1.0 0.6742180122166563 8 Q09666,P15311 2 +14 3 3 protein binding 0.5331354941791716 0.9297782533027288 0.3524859081413396 1.0 0.6742180122166563 6 O14974 1 +Nadplus adp ribosyltransferase activity 0.5805824859026739 0.9282649434872272 0.3532701539722043 1.0 0.6748122914348406 5 Q9ULX3,P09874 2 +Histone lysine n methyltransferase activity 0.4330529223805417 0.9134696372434474 0.3609955953888222 1.0 0.6786526694314929 11 Q15910,Q96L73 2 +Guanylate kinase activity 0.6212204152124114 0.905904316147226 0.3649864996200076 1.0 0.6790643711609962 4 Q14168 1 +Atpase binding 0.3216007415806012 0.8968625851947506 0.3697922470322337 1.0 0.6790643711609962 29 Q9UII2,Q04323,P36543,P55769,P25685,P05026 6 +Keratin filament binding 0.7347367562420359 0.8899030644498523 0.3735179383288649 1.0 0.6799128127724376 3 P58107 1 +Lysine n methyltransferase activity 0.4210058011051122 0.8888944972843918 0.374059783065884 1.0 0.6799128127724376 12 Q15910,Q96L73 2 +Insulin receptor substrate binding 0.7108599779492779 0.8864431648715209 0.3753787678478932 1.0 0.6799128127724376 2 Q05655 1 +Phosphotransferase activity phosphate group as acceptor 0.4085760014776456 0.8862130637070983 0.3755027253697602 1.0 0.6799128127724376 13 Q9UIJ7,P27144,Q14168,Q9UDY2 4 +Peptidyl proline dioxygenase activity 0.6119691119691105 0.8678708966644434 0.3854650128672165 1.0 0.6934291003866051 4 P13674,P07237,Q32P28 3 +Procollagen proline dioxygenase activity 0.6119691119691105 0.8678708966644434 0.3854650128672165 1.0 0.6934291003866051 4 P13674,P07237,Q32P28 3 +Supercoiled dna binding 0.5662868319263348 0.865403911880405 0.3868171346623412 1.0 0.6942247064154109 5 O75475,P26583 2 +G protein coupled glutamate receptor binding 0.7229114971050434 0.8458343844776887 0.3976451408245014 1.0 0.7048141408761528 3 P0DP25,O14745 2 +Snrna binding 0.3131830256551853 0.8443322580362813 0.3984837650491726 1.0 0.7053868944054715 32 Q7L2J0,P08621,Q8TEQ6,Q9NY93,Q9NW64,P55769,O43172,P09661,P09012,Q9NR30,O94992,Q00839,P08579 13 +Cyclin dependent protein serine threonine kinase inhibitor activity 0.7001102535832355 0.8430000630543558 0.3992284085295665 1.0 0.7053868944054715 2 O94992 1 +Ribosomal small subunit binding 0.4134510190353881 0.8425650653783151 0.3994717359896249 1.0 0.7053868944054715 12 P23588,Q6PKG0,Q15056 3 +Atp hydrolysis activity 0.3319128959799036 0.833229250608848 0.4047154487843782 1.0 0.7109858288009121 178 P10809,O76031,P54277,Q14839,Q96Q89,Q9UN37,O00139,Q9P2D1,P36776,P25205,Q9BVQ7,Q9UIJ7,Q92878,P07900,P0DMV9,Q96TA2,Q9HCK8,P54132,P38646,Q7L2E3,Q7L014,P18074,P38935,Q12931,P17980,P20020,P55072,Q8WVB6,O60264,O75449,P13984,P14625,Q8TDD1,P61604,Q9NR30,Q9Y4L1,O14646,Q02241,O95757,P62191,Q14807,Q9H078,O00571,P50991,Q9Y496,Q9NP58,Q9GZR7,P78371,P17987,P11142,P17844,O15381,P35998,Q13283,Q9BQ39,Q92614,P35251,Q96QE3,Q86XP3,Q9NY93,P08238,Q6ZRS2,P54652,Q9BUQ8,Q86Y91,O95347,Q14683,Q99661,Q9Y4W6,Q8IY37,P33176,Q96T23,Q9NTJ3,A3KMH1,Q96GQ7,Q9UQE7,Q9UKV3,Q8TB37,Q9UJV9,P33991,P34932,Q9UHI6,Q92499 83 +Molecular adaptor activity 0.301783508744921 0.8314111540062774 0.4057414000810855 1.0 0.7109858288009121 130 Q8IZP0,Q8TD16,Q9Y2J2,O60271,Q9NZM3,Q86YP4,P49790,Q6SZW1,O43752,Q12802,P12270,Q14141,O75146,Q92878,O14745,P59998,Q9NX63,O00291,O95721,P05026,Q7Z434,Q15019,P35579,Q5VU43,Q13428,Q9UDY2,P51610,Q9UHI6,Q14978,Q13112 30 +Tpr domain binding 0.6028681742967472 0.8307142701602958 0.4061350629080298 1.0 0.7109858288009121 4 P08238,Q9UNE7,P07900 3 +Ubiquitin like protein ligase activity 0.2846932420733012 0.8286264948125295 0.4073157909006362 1.0 0.7121779166054069 51 Q7Z6E9,O60858,Q99496,Q9H1B7,O75150,O75592,Q7Z6Z7,Q13356,Q13049 9 +Calcium channel regulator activity 0.5569862977525514 0.8248764439664311 0.409441741120446 1.0 0.7145868112765627 5 Q9UKS6,Q9NWR8 2 +Beta 2 adrenergic receptor binding 0.6923925027563654 0.812087886559949 0.4167412034287465 1.0 0.7206992899101503 2 O14745 1 +Myosin ii binding 0.6923925027563654 0.812087886559949 0.4167412034287465 1.0 0.7206992899101503 2 O14745 1 +Profilin binding 0.7118645551874407 0.8050562817884074 0.4207872023858487 1.0 0.7250565458280949 3 Q14247 1 +Heparin binding 0.3943942911537952 0.7964404391834637 0.4257760814150471 1.0 0.7318828902490255 13 P47914,P51858,P10586,P30533 4 +Minor groove of adenine thymine rich dna binding 0.7089899402797089 0.794512790835147 0.426896965634616 1.0 0.7328369578652487 3 P07305 1 +Protein kinase c activity 0.593138362856406 0.7913120146994534 0.4287619390013673 1.0 0.7328369578652487 4 Q16513 1 +Peptide lysine n acetyltransferase activity 0.4123687827949278 0.7905314901455746 0.4292174392339225 1.0 0.7328369578652487 11 Q6ZRS2,Q9UPT9 2 +Rna polymerase ii ctd heptapeptide repeat kinase activity 0.5028795249839881 0.7875184744730976 0.4309784179708029 1.0 0.7328369578652487 6 O60885,P11802,P28482,P50750 4 +Poly pyrimidine tract binding 0.3682140018862843 0.7868007326144185 0.4313985245733103 1.0 0.7328369578652487 15 P05455,P26599,P11940,Q07666,Q13310,Q00839 6 +Cation chloride symporter activity 0.6857772877618735 0.7857941378764092 0.4319881014784623 1.0 0.7328369578652487 2 P55011 1 +Potassium chloride symporter activity 0.6857772877618735 0.7857941378764092 0.4319881014784623 1.0 0.7328369578652487 2 P55011 1 +Ammonium transmembrane transporter activity 0.6857772877618735 0.7857941378764092 0.4319881014784623 1.0 0.7328369578652487 2 P55011 1 +Ubiquitin like modifier activating enzyme activity 0.4417796723738137 0.7806005862246548 0.4350374468887259 1.0 0.7336430317354254 8 Q9UBT2,Q13564,Q9GZZ9,P22314 4 +Rna polymerase ii core promoter sequence specific dna binding 0.4296547017000528 0.7789347328002343 0.4360181626158876 1.0 0.7344277561792434 9 O75367,Q15910,P84243,P26367 4 +G quadruplex dna binding 0.4997518007968363 0.773040109199846 0.4394986436550845 1.0 0.7381625407939807 6 Q92878 1 +Protein domain specific binding 0.3383313419526122 0.7718184365642591 0.4402219706123542 1.0 0.7381625407939807 203 Q9BY67,Q9Y3C6,Q8IZP0,Q9UQN3,P11387,P51608,P38159,P46940,Q14676,Q15648,Q9H7N4,Q9HD42,Q92665,Q9UN37,P40818,P62805,P52272,O75528,Q9Y5K6,O75146,P15311,P31689,Q9BV73,P80723,Q96PU8,P35251,P35269,O94832,Q9Y490,O14745,P0DMV9,O43815,O43491,Q96IZ0,Q14980,Q99496,Q99459,Q96D71,Q96EB6,Q9P1Z2,Q13185,Q13111,Q9Y6W5,Q9HCK8,Q8N8S7,O14964,P08238,Q07960,P35579,Q7Z434,Q14498,P26583,Q9UDY2,Q9UQ35,Q16625,Q96JJ3,P54652,O75494,Q9Y2W2,Q9UHI6,Q13112,P20020,P22059,Q14978,P53990,P55072,P67870,Q9UQB8,P78536,Q8N3R9,P11142 71 +Channel inhibitor activity 0.5431504687564148 0.7652325436533076 0.4441330841151099 1.0 0.7419573796764732 5 Q9UKS6,Q9NWR8 2 +Intramolecular transferase activity phosphotransferases 0.5830115830115749 0.7507016368803482 0.4528322376981717 1.0 0.7503324868835984 4 P18669,Q96G03,O95394 3 +Non membrane spanning protein tyrosine kinase activity 0.5819084390512912 0.7463045875034301 0.4554834408550983 1.0 0.752974365682732 4 P19525,Q05655,Q9UIG0 3 +Protein serine threonine phosphatase inhibitor activity 0.674476295479623 0.7413484548432019 0.4584821891733579 1.0 0.7561772217268924 2 Q12972 1 +Plus end directed microtubule motor activity 0.4901055184721142 0.7287195779361956 0.4661732144412562 1.0 0.7641509986869596 6 Q86Y91,Q9Y496,P33176 3 +Lys63 specific deubiquitinase activity 0.6686879823594194 0.7188337397407847 0.4722433663457743 1.0 0.7680151370945295 2 O00487 1 +Protein serine threonine kinase activity 0.2532046170106207 0.7181478029328122 0.4726661580574753 1.0 0.7680151370945295 84 Q13464,Q16513,O60885,P11387,O95747,P11802,Q12802,Q13523,Q13043,Q9Y5S2,P11274,Q99640,P51956,O00311,P42345,Q2M2I8,O96013,Q9H2G2,P67870,P25440,O75116 21 +Adenyl nucleotide binding 0.199660658474623 0.7147560375182215 0.4747598045818384 1.0 0.7699060598510774 511 P46013,Q9NWH9,Q05682,Q7Z406,P20585,Q8NE71,Q9UN37,Q9P2D1,P25205,Q13523,Q9H981,Q9UIJ7,P61088,Q92878,O00764,O94832,P0DMV9,Q9H4M9,Q96EY1,Q9HCK8,P54132,Q7L2E3,Q5ST30,Q7L014,P51956,Q2M2I8,P17980,O43237,P20020,P55072,O00159,Q13464,Q8WVB6,P11387,P13984,Q8TDD1,P61604,Q9NR30,Q9UG63,Q9Y4L1,Q9UIG0,Q9Y2W1,Q02241,P31689,Q13043,Q9Y5S2,O43795,O95757,P11274,Q13308,Q99640,Q9UGM6,Q14807,Q9H078,Q9Y6G9,P35579,O14678,Q9NS86,Q9NP58,Q9Y496,Q9GZR7,Q9UBT2,Q14978,Q14692,P22314,O75116,Q8NCM8,Q8N3R9,O94992,P11142,Q13283,Q9NRZ9,Q9H3P7,Q9BQ39,Q92614,Q9BTE6,Q96QE3,Q86XP3,Q9UM54,P35580,Q6ZRS2,O00311,P54652,Q9H2G2,Q9BUQ8,O95347,Q14683,Q16513,Q13572,P27144,O95747,P33176,A3KMH1,Q96GQ7,Q9UQE7,Q8TB37,P33991,Q9H3H1,Q9GZZ9,Q96T60,P42345,P49916,Q9UHI6,Q92499,O96013 105 +Phosphatidylinositol 4 phosphate binding 0.4144717670657413 0.6966003316926683 0.486052948222331 1.0 0.7778309573206141 9 O60493,Q9NS86 2 +Single stranded telomeric dna binding 0.4807073434332548 0.6860747114868394 0.4926659968223679 1.0 0.7828041415258301 6 P09651,Q9NYB0,Q92878 3 +Dihydropyrimidinase activity 0.6601433296582186 0.6859341930193251 0.4927546069815225 1.0 0.7828041415258301 2 Q9BPU6 1 +Dioxygenase activity 0.3328677932807047 0.6826747096122832 0.4948124139547838 1.0 0.7833587582804511 21 Q6P6C2,Q7LBC6,Q9Y2K7 3 +Zinc ion binding 0.308540877295648 0.676990579045466 0.4984119317549127 1.0 0.7833587582804511 155 Q9UBW7,Q8N4Q0,O60858,Q05682,Q86YP4,Q15637,Q15437,Q13049,Q9HD42,Q92974,Q5VUA4,Q9UIG0,P46939,Q7Z6E9,Q14966,Q8WXI9,O75592,O95487,O00764,Q9Y2K7,Q9UPT9,P26358,Q99496,Q15075,P62273,Q99640,Q08257,P54132,Q9H3H1,Q9GZZ9,Q96L73,Q5F1R6,P09874,P49916,Q5SVZ6,P43243,P14373,Q969S3,Q5VZL5 39 +Structural constituent of muscle 0.4784708587851707 0.6760120856460878 0.4990329718471054 1.0 0.7833587582804511 6 Q15149,P67936,Q16527 3 +Signaling receptor regulator activity 0.320487849990322 0.6612528741103432 0.508450157970068 1.0 0.7833587582804511 23 P26583,P30533,Q9Y3E1 3 +Adp binding 0.3335997839195626 0.6571065347121394 0.5111124174031736 1.0 0.7833587582804511 20 Q9UM54,P35579,Q92614 3 +Transforming growth factor beta receptor binding 0.5172379208613642 0.6561199101065006 0.5117469748302608 1.0 0.7833587582804511 5 P62942,Q9Y4E8 2 +Pdz domain binding 0.3420138959994021 0.6436867078823504 0.5197786109996487 1.0 0.7877679903028091 17 O14745,Q9BY67,P20020,P78536 4 +Telomeric dna binding 0.3302641500296027 0.6331457054983111 0.526638497658499 1.0 0.7958216958254094 20 P19338,Q92878,Q9HAU5,P54132 4 +Protein kinase a binding 0.3332345637538556 0.6278809434617285 0.5300819355959543 1.0 0.7968003778736654 19 Q12802,P35241,Q02040,Q9H3P7,P15311,O43164,Q9Y6W5,Q96M27,Q02952 9 +Atp dependent activity acting on rna 0.2670611777073929 0.6061664157951637 0.5444042516517815 1.0 0.8131824513666548 49 Q7L014,Q13283,Q7L2E3,Q96GQ7,Q9NY93,Q9BQ39,Q9UHI6,Q9GZR7,Q8TDD1,Q9BUQ8,Q92499,Q8IY37,Q9NR30,Q86XP3 14 +Atpase activator activity 0.3400422590420403 0.6014971395402107 0.547508916420091 1.0 0.8144052253639141 15 O75190,P31689,P25685,Q99543,P05026 5 +Ubiquitin like protein binding 0.2792722212237906 0.5988315661957526 0.5492852101259631 1.0 0.8161954373613112 38 P54727,Q5TDH0,Q04323,Q9UNZ2,Q9UBT2,O14964,Q8NC51,P61088,Q13049,O95071 10 +Calcium dependent protein kinase activity 0.6519092511070836 0.5925121735364967 0.5535076713685141 1.0 0.8191759081027675 3 Q16513 1 +Nuclear localization sequence binding 0.3368054435874598 0.5810638068396557 0.5611974505432582 1.0 0.8269972771707786 15 P35658,P49790 2 +Nucleobase containing compound kinase activity 0.3214664267066383 0.5711665975082098 0.5678867181289708 1.0 0.8325240902256136 20 Q9UDY2,P27144,Q9BZX2,Q14168,Q9UIJ7,O94992,Q96T60 7 +Transcription corepressor binding 0.3331782604384333 0.5584182568302596 0.5765588089116211 1.0 0.840618158046532 15 Q15910,Q9H582,P51784,O95785,P51858 5 +Transforming growth factor beta binding 0.6254134509371465 0.5570168411873149 0.577515922749265 1.0 0.840618158046532 2 P06756 1 +Phosphate ion binding 0.4845113691105504 0.524758433745142 0.5997511303595768 1.0 0.8598041858776629 5 P13995 1 +Phosphatidylinositol 3 4 bisphosphate binding 0.6280467407661365 0.5133894318031814 0.6076789366487032 1.0 0.8682785849330484 3 O75146 1 +Ubiquitination like modification dependent protein binding 0.4385843971778238 0.5034076091620929 0.6146777229190441 1.0 0.8724260509558146 6 Q9UER7,Q99543 2 +General transcription initiation factor binding 0.3185300972772817 0.4917769912141208 0.6228770038335616 1.0 0.878811614319629 17 P42345,O60869,Q14978,O15160,P35269 5 +Long chain fatty acid binding 0.6017089305402363 0.4743612416207806 0.6352423267859346 1.0 0.8883418210696338 2 P52758 1 +Gtpase activator activity 0.2542020715491071 0.4721340105253498 0.6368311378560736 1.0 0.8890155822854423 49 Q4KMP7,Q96HS1,Q8IYB5,A1A4S6,Q92888,P11274,Q07960,Q9H0H5,Q86VI3,Q15437,P46940,P43487,Q15042,Q8N6T3 14 +Mhc class ii protein complex binding 0.405286246597784 0.471063013223693 0.6375957369092786 1.0 0.8890155822854423 7 P08238,P11142,P05026 3 +Phosphatase binding 0.2552917781485531 0.4675172030778025 0.6401298869772531 1.0 0.8916765287806312 48 O60493,Q96QC0,O43815,Q9NWH9,Q9NX63,O95793,Q9Y496,P19022,P46940,P55072,Q9NYB0,O14745 12 +Protein folding chaperone 0.2790156154174932 0.4639219862104654 0.642703640039731 1.0 0.8923337942471243 26 P50991,P0DMV9,P11142,O75190,P54652,Q9UHV9,P25685,P78371,P08238,P38646,P07900 11 +Peptidyl proline 4 dioxygenase activity 0.611800385993931 0.4618182422912009 0.6442116678439349 1.0 0.8923337942471243 3 P13674,P07237 2 +Procollagen proline 4 dioxygenase activity 0.611800385993931 0.4618182422912009 0.6442116678439349 1.0 0.8923337942471243 3 P13674,P07237 2 +Eukaryotic initiation factor 4e binding 0.5058430835226164 0.4607400346154605 0.6449851284733601 1.0 0.8923337942471243 4 Q6PKG0,Q04637 2 +Ww domain binding 0.4663530305313816 0.4559064578817724 0.6484572454842568 1.0 0.8945320182140037 5 P50570,Q8N8S7,Q9Y2W2 3 +Structural constituent of presynaptic active zone 0.5953693495038487 0.4531162981403941 0.6504650000031078 1.0 0.8952959793425288 2 Q8IUD2 1 +Protein serine kinase activity 0.2418961405889505 0.4471026307175105 0.6548009596751516 1.0 0.8996633705363424 71 Q13464,P11274,Q16513,P51956,O00311,P42345,Q2M2I8,Q13523,O96013,O95747,Q13043,Q99640,Q9H2G2,O75116,P11802,Q9Y5S2 16 +Snorna binding 0.2690591640778196 0.4416814838007751 0.6587197104208511 1.0 0.9017056554752284 31 Q96DE0,Q9NY93,O60832,Q9NPE3,P55769,O43818,P78316,Q14978,Q14692,Q2NL82,Q9NR30 11 +Protein phosphatase 1 binding 0.4614280615030033 0.4378190849697706 0.6615174350067818 1.0 0.903950723679282 5 O95793 1 +Hyaluronic acid binding 0.5906835722160868 0.4376658967311089 0.6616284945947306 1.0 0.903950723679282 2 O75330 1 +Sodium ion transmembrane transporter activity 0.3955204908779183 0.4297018672585473 0.6674125249549041 1.0 0.9101079885748692 7 P05026 1 +Protein self association 0.3109943599859621 0.4265980901360874 0.6696720890441714 1.0 0.911205972782148 15 Q13049,P11166,O14745 3 +Atp dependent peptidase activity 0.4193413674538815 0.4259613057279462 0.6701360417373272 1.0 0.911205972782148 6 Q9Y4W6,O76031,P36776 3 +Lrr domain binding 0.5973755503880898 0.41779421727448 0.6760975792210124 1.0 0.914946866467182 3 Q96IZ0 1 +Leucine zipper domain binding 0.5973755503880898 0.41779421727448 0.6760975792210124 1.0 0.914946866467182 3 Q96IZ0 1 +General transcription initiation factor activity 0.3650240303167222 0.4046158031214917 0.6857599404700201 1.0 0.9253862833047144 8 P17480,P29083,P13984 3 +Phosphatidylinositol binding 0.2412307357125212 0.3986603699391166 0.6901434723926092 1.0 0.9278884455836984 67 O60493,Q9H0H5,Q14980,O75146,Q15075,Q9NS86,O00291,Q53T59,Q9Y5X2,Q9Y490 10 +Pyruvate dehydrogenase activity 0.4504690769714051 0.398558190381941 0.6902187735569967 1.0 0.9278884455836984 5 P09622,P10515,P11177 3 +U4 snrna binding 0.4052580652552517 0.3723099937535341 0.709662058677365 1.0 0.9433474194172062 6 Q8WWY3,Q8TEQ6,O43172,P55769 4 +Guanyl nucleotide exchange factor activity 0.2532920941954849 0.369787811257673 0.7115405977228058 1.0 0.9449630491658884 38 Q12802,Q92888,O75592,Q9NZM3,Q5VZ89,Q96N67,Q92974,Q15042 8 +O methyltransferase activity 0.3374817719854233 0.3640984703125838 0.7157844790612977 1.0 0.9495336841678632 10 Q7L2J0 1 +Protein phosphatase binding 0.2515430520746475 0.3623549481935587 0.7170868012759559 1.0 0.9495336841678632 40 O60493,O43815,Q9NWH9,O95793,P19022 5 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.3312414359375066 0.3574770536922012 0.7207347013965943 1.0 0.9518507409547238 11 Q9H0H5,O75146,O43795 3 +Molecular function activator activity 0.2927109054423905 0.3530954237423899 0.7240169035406441 1.0 0.9531343562119352 18 O75190,P31689,P25685,Q99543,P05026 5 +Histone threonine kinase activity 0.5748552522746035 0.3527618912824898 0.7242669556956942 1.0 0.9531343562119352 3 Q9Y4B6,Q99986 2 +Small ribosomal subunit rrna binding 0.3981851196284121 0.3464453664743745 0.7290080360104043 1.0 0.9536084238506932 6 P62263,P82912 2 +Protein disulfide isomerase activity 0.3275962170536647 0.3409208199998672 0.7331631906675762 1.0 0.957614616591472 11 P13667,P30040,P30101,Q8NBS9 4 +Glycosaminoglycan binding 0.2897443028575139 0.3367729767616531 0.736288045723628 1.0 0.9599363816616376 18 P47914,P51858,P10586,P30533 4 +P type transmembrane transporter activity 0.3829590353624941 0.2934484506639943 0.7691793962865605 1.0 0.9896116882820852 6 P05026 1 +Pentosyltransferase activity 0.2856121726866037 0.2932717206312177 0.7693144674675274 1.0 0.9896116882820852 15 Q7Z4H8,Q9ULX3,P09874,Q96EB6 4 +Histone methyltransferase activity 0.28147321689084 0.2930728198689622 0.7694664916607372 1.0 0.9896116882820852 18 Q15910,Q96L73 2 +Sumo binding 0.417826041733024 0.2907156135575547 0.7712688292267407 1.0 0.9910352404401312 5 Q8NC51 1 +Inositol phosphate phosphatase activity 0.5439462727810859 0.271773180562069 0.7857964281084984 1.0 1.0 3 Q96PE3 1 +Inositol trisphosphate phosphatase activity 0.5439462727810859 0.271773180562069 0.7857964281084984 1.0 1.0 3 Q96PE3 1 +Phosphatase regulator activity 0.2458823502251209 0.2678844310825777 0.788788278052015 1.0 1.0 28 Q96QC0,O14974,Q15435 3 +Cytokine receptor binding 0.253710529716464 0.2599459405815461 0.7949054735268053 1.0 1.0 25 Q9Y5K6,P48681 2 +Ap 2 adaptor complex binding 0.5380294560410501 0.2574593586919412 0.7968241851070326 1.0 1.0 3 Q2M2I8 1 +Co smad binding 0.5373549587930133 0.2558530464451007 0.7980643115760708 1.0 1.0 3 P26367 1 +Dystroglycan binding 0.4054372278670259 0.2538053075489475 0.7996459728536944 1.0 1.0 5 Q15149,P18206 2 +Protein containing complex binding 0.2604160445241765 0.2507058427094584 0.8020415430950492 1.0 1.0 416 Q96ST3,Q96SN8,Q9UPN4,P84243,Q12834,Q8TD16,Q6PKG0,P18754,P10809,O75150,Q14839,Q7Z406,Q8N183,Q12824,P62993,Q9UN37,P07942,P08579,P48681,O94832,P06748,Q14980,P62750,Q9BY77,Q9UHB6,P05026,Q01082,Q2M2I8,Q5SSJ5,P55196,P05204,Q14315,P53990,P55072,O00159,Q9Y281,O60885,O60869,P98179,Q99543,Q92922,Q9NQ48,Q9UII2,P12270,P16402,P68402,Q9Y5K6,Q8WXI9,Q9H814,Q7Z3B4,Q9Y5S2,Q9Y490,O43795,Q15910,P05114,P11047,Q96EB6,Q92522,P35579,O94776,Q9Y496,Q14978,P78536,P47755,O94992,P11142,P45973,P46821,Q96HS1,Q14331,P35611,P46940,Q15648,Q32P28,P09012,O95983,P46939,O60493,Q92614,Q969G3,Q9ULV4,P09496,P62314,Q13813,P35269,O14745,P16403,P62942,P10412,P07305,O95400,O43815,O43491,Q14137,Q9UM54,Q15056,Q9Y6W5,O75369,P29966,P35580,P08238,P54727,Q9H269,Q8NC51,P21333,Q14683,Q04323,Q9BXP5,Q9Y5B9,P10586,P09104,P35221,O95219,Q13561,Q15102,Q66K74,Q6WCQ1,P49006,O75146,P15311,Q9UJU6,P50454,P50570,O95456,P61011,Q14008,Q14247,P67936,Q00839,P59998,P23588,Q9UQE7,Q86VI3,O00291,O95785,Q07666,P58107,P09132,P42345,Q8TAQ2,Q13596,O15533,O75367,O60828,Q06787 145 +Mhc protein complex binding 0.321936285903615 0.2359039673789812 0.8135071896058017 1.0 1.0 8 P08238,P11142,P05026 3 +Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor 0.4302261445118515 0.2309984848984561 0.8173159790789515 1.0 1.0 4 P08559,P11177,Q02218 3 +Poly g binding 0.3617549668874182 0.2263400078349595 0.8209369839014977 1.0 1.0 6 Q86TB9,Q8TCS8,O14979,Q06787,Q00839 5 +Anion cation symporter activity 0.5226185349143787 0.2220852496303568 0.8242475202456583 1.0 1.0 3 P55011 1 +Protein serine threonine kinase inhibitor activity 0.3355869174832873 0.2117073230065871 0.8323353746649758 1.0 1.0 7 O75367,P42771,O94992 3 +Protein heterodimerization activity 0.2183365911463758 0.2108211952837251 0.8330267987896971 1.0 1.0 72 P84243,Q9BVA1,Q8TBC4,P35611,P62805,Q13564,Q15102,O43709,P68402,O75146,P67936,P16104,Q9UQE7,O00291,P05026,Q13428,Q9UBT2,Q14978,Q9P0M6,Q13596,O00267,O75367,Q9NRF9,Q06787,Q14683 25 +Extracellular matrix binding 0.3556843267108245 0.2086749150781517 0.834702023894738 1.0 1.0 6 O94813,P17301,P17931,P05556,P06756 5 +Pseudouridine synthase activity 0.4209325740684083 0.207946860742171 0.8352704592501705 1.0 1.0 4 O60832 1 +Type i transforming growth factor beta receptor binding 0.5150446152574601 0.2057378174630495 0.8369957163668575 1.0 1.0 3 P62942 1 +Adenylate cyclase binding 0.5148692317949721 0.2053675232432074 0.8372849921702858 1.0 1.0 3 Q02952 1 +Pre mrna intronic binding 0.3515452538631401 0.1970439167526156 0.843793170820976 1.0 1.0 6 Q9Y580,P22626,P14866,Q13148,Q6P2Q9 5 +Deoxyribonuclease activity 0.2574964043887463 0.1899438836377783 0.8493531042164106 1.0 1.0 19 Q92878,P18887 2 +Methyl cpg binding 0.2928145209851144 0.1885418198434756 0.8504519358124276 1.0 1.0 10 P26358,Q9Y3Y2,P51608 3 +Nucleoside triphosphatase regulator activity 0.2117721502645166 0.1861333133435271 0.8523402181090145 1.0 1.0 85 Q96HS1,Q8IYB5,A1A4S6,Q9H0H5,Q9NZM3,Q15437,Q96N67,Q92974,Q8N6T3,Q12802,Q92888,O75592,Q5VZ89,P43487,P11274,Q86VI3,Q96EY1,Q07960,Q15042,Q4KMP7 20 +Tau protein binding 0.2544019350827947 0.1849413075981323 0.8532750710279631 1.0 1.0 20 Q13526,Q13464,P54652 3 +Chemokine binding 0.5012990229193267 0.1778636451521606 0.8588300625104996 1.0 1.0 3 P09429 1 +Sulfurtransferase activity 0.374620689655176 0.1728479194963103 0.8627709695669492 1.0 1.0 5 Q9Y697,Q2VPK5,P25325,O75648 4 +L serine transmembrane transporter activity 0.497950605784044 0.1714286082033365 0.8638867616309052 1.0 1.0 3 Q9H9B4 1 +Lamin binding 0.2946699806683289 0.1711053965217164 0.8641408926404615 1.0 1.0 9 P42167,P42166,Q5SNT2,Q9UH99,Q14739,Q9ULX6,Q5JTV8,O94901 8 +Alpha tubulin binding 0.2945674239506681 0.1707971213100459 0.8643832926771218 1.0 1.0 9 Q9H0H5 1 +Cell cell adhesion mediator activity 0.2508281259323722 0.1699778913821662 0.865027523740435 1.0 1.0 20 P04083,O96013,Q9UQB8,Q9Y639,O00151,Q8WX93,Q9NYL9,Q96HC4 8 +Nitric oxide synthase regulator activity 0.3729800872283894 0.168995212843515 0.8658004068407381 1.0 1.0 5 P08238,P0DP25,P07900 3 +N6 methyladenosine containing rna binding 0.3699310344827623 0.1619614645767574 0.8713361999595484 1.0 1.0 5 P07910,Q96MU7,Q9Y5A9,P22626 4 +Carbon sulfur lyase activity 0.295343754029396 0.1539753165924948 0.8776291979735125 1.0 1.0 8 Q96I15 1 +Phospholipase binding 0.3946283309256234 0.1497795999645531 0.8809385046495137 1.0 1.0 4 P84103 1 +Ubiquitin like protein transferase activity 0.2118745664418102 0.1449938939639066 0.8847156927565027 1.0 1.0 70 Q14527,O60858,O75150,Q8TBC4,Q7Z6Z7,Q13049,Q9NR09,Q7Z6E9,O75592,P61088,O95628,P19474,Q13263,Q5VTR2,Q99496,Q9NT62,Q9H1B7,P49792,P14373,O43164,Q13356,O95071 22 +Opsonin binding 0.3896856039713241 0.1400473939457724 0.8886225443908664 1.0 1.0 4 P35232,P06756,Q07021 3 +Protein deacetylase activity 0.3888220833351365 0.1383864728562993 0.8899349872505096 1.0 1.0 4 Q96EB6 1 +Aminoacyl trna editing activity 0.2738812319612344 0.1316059452553373 0.8952959827993798 1.0 1.0 10 Q9BTE6,P26640,Q15031,Q5ST30 4 +Laminin binding 0.3555862068965555 0.1310974314974158 0.8956982329960359 1.0 1.0 5 P05556,P17931,P17301,O94813 4 +Importin alpha family protein binding 0.3218744154987091 0.1238722545385214 0.901416421392115 1.0 1.0 6 Q08379 1 +Cell adhesion mediator activity 0.2317875636985601 0.1220223232825867 0.9028813389529784 1.0 1.0 23 P04083,O96013,Q9UQB8,Q9Y639,O00151,Q8WX93,Q9NYL9,Q14126,Q96HC4 9 +Single stranded dna helicase activity 0.2633648923235321 0.1212801607224986 0.9034691334636976 1.0 1.0 12 P33991,P25205 2 +Serine transmembrane transporter activity 0.3771302453320203 0.1170515068355886 0.9068192374206108 1.0 1.0 4 Q9H9B4 1 +Syntaxin binding 0.2334257996888783 0.1120575162568445 0.9107778023147404 1.0 1.0 21 O43752,O75150,Q08379 3 +Chloride channel inhibitor activity 0.4618141714915862 0.1109405223791063 0.9116635117081816 1.0 1.0 3 O15400,Q9H4A3 2 +Histone acetyltransferase binding 0.2961634004968269 0.1100575257826454 0.912363752976148 1.0 1.0 7 Q9H6U6,P42224,P12004,P26367,P04637,Q15650 6 +Dopamine receptor binding 0.2959852060428797 0.1096815195432025 0.912661957246616 1.0 1.0 7 P50570,O14745 2 +Endonuclease activity 0.2118854838128647 0.1095825887788368 0.9127404196293376 1.0 1.0 43 Q13283,Q12972,P18887,Q92878,Q9ULX3,P39748,Q96T60 7 +C x3 c chemokine binding 0.4487320837927073 0.0994005613659164 0.9208202370670004 1.0 1.0 2 P06756 1 +Collagen binding involved in cell matrix adhesion 0.4487320837927073 0.0994005613659162 0.9208202370670008 1.0 1.0 2 P17301 1 +Cell matrix adhesion mediator activity 0.4487320837927073 0.0994005613659162 0.9208202370670008 1.0 1.0 2 P17301 1 +Protein n terminus binding 0.2054580978126587 0.0960206093073471 0.9235042043306748 1.0 1.0 49 Q9UER7,P0DMV9,P09874,O60934,Q9UQ35,P51608,Q96KP1,O14745 8 +Phosphatidylinositol phosphate kinase activity 0.4454244762954635 0.0948749610333514 0.9244141449894532 1.0 1.0 2 O00443 1 +Transferase activity transferring one carbon groups 0.2049174759205704 0.0929524100866988 0.9259413687121908 1.0 1.0 69 Q7L2J0,Q15910,Q8IY81,Q05682,Q9H7B4,Q96L73 6 +Udp glucosyltransferase activity 0.3347855041631269 0.0929113913111407 0.9259739559384984 1.0 1.0 5 P13807,Q7Z4H8 2 +Ionotropic glutamate receptor binding 0.334344827586211 0.092186049596257 0.9265502216548762 1.0 1.0 5 P41440,Q15334,P46459,O75955 4 +Rna stem loop binding 0.2681248179601302 0.0898444668145269 0.9284108116429866 1.0 1.0 8 P07814,Q06787,P35580 3 +Neutral amino acid transmembrane transporter activity 0.3035502706478638 0.0878526027979452 0.9299938283650058 1.0 1.0 6 Q9H9B4 1 +Gtpase binding 0.2155157498300451 0.0819105080738305 0.9347178782864872 1.0 1.0 103 Q13464,Q16513,Q8TD16,Q5VSL9,Q96N67,P46940,Q92974,Q13177,Q12802,O75592,P09496,Q96KP1,P43487,Q8IWJ2,Q9Y5S2,Q9H4M9,Q86VI3,Q01082,Q96CN9,Q07960,Q15042,Q12904,O60610,P55196,Q9Y496,O75116,Q6WKZ4,O00159,P21333 29 +Rna polymerase ii general transcription initiation factor activity 0.2803219033974806 0.0795587641375492 0.9365881926604562 1.0 1.0 7 P29083,P13984 2 +Ligase activity forming phosphoric ester bonds 0.3521110773040494 0.0785501302295441 0.937390455216081 1.0 1.0 4 P49916 1 +G protein coupled receptor binding 0.2053063522024324 0.0768168373097296 0.9387692560800392 1.0 1.0 37 P21333,P48681,O14745,Q9BRK0 4 +Phosphatase activator activity 0.2598012147984558 0.0742339301540312 0.94082424796347 1.0 1.0 8 Q14738,Q13362,Q15257,Q16537,P0DP25,P35269,O94766 7 +G protein beta subunit binding 0.4206174200661419 0.0656249368831709 0.947676435142676 1.0 1.0 2 Q9UBI6 1 +Bubble dna binding 0.420954410890711 0.0618408694806866 0.9506895566143748 1.0 1.0 3 P54132 1 +Cargo adaptor activity 0.2397539883519531 0.0611798530939497 0.9512159745740312 1.0 1.0 11 O75146 1 +G rich strand telomeric dna binding 0.3110535256454424 0.0586447356850947 0.9532350780520338 1.0 1.0 5 P09651,Q9NYB0 2 +Translation elongation factor activity 0.2349364289662827 0.0574760438573211 0.9541659887876262 1.0 1.0 12 P49411,P24534,P43897,P26641,Q96RP9,Q9Y450,O00178,Q7Z2Z2,Q05639,P29692,P63241 11 +Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity 0.4101433296581998 0.0556280266013149 0.955638137069216 1.0 1.0 2 Q01968 1 +Inositol polyphosphate 5 phosphatase activity 0.4101433296581998 0.0556280266013149 0.955638137069216 1.0 1.0 2 Q01968 1 +Phosphatidylinositol trisphosphate phosphatase activity 0.4101433296581998 0.0556280266013149 0.955638137069216 1.0 1.0 2 Q01968 1 +Histone kinase activity 0.2436421048720696 0.0553778991788389 0.9558374027140556 1.0 1.0 9 P06493,P54646,Q99986,Q9Y4B6,Q9UIG0 5 +Calcium dependent protein serine threonine phosphatase activity 0.4105321202095344 0.0523611074812645 0.9582409633168952 1.0 1.0 3 Q13555,P49593 2 +Ligase activity forming carbon sulfur bonds 0.2140834017432889 0.0523543206096977 0.9582463710396754 1.0 1.0 17 Q13564,P53597,Q9UBT2,P22314,Q9GZZ9 5 +Tumor necrosis factor receptor superfamily binding 0.3292884721456174 0.0515833969070145 0.9588606490746096 1.0 1.0 4 Q13546,P42224,Q12931 3 +Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor 0.2437879624516835 0.0492179440637432 0.960745611301095 1.0 1.0 8 P00558,P00390,P35754,P09622,Q16881,Q6DKJ4,P30048 7 +Phosphatidylinositol bisphosphate binding 0.2112433798148181 0.047908392215651 0.9617892510516666 1.0 1.0 19 O60493,O75146,O00291 3 +C acyltransferase activity 0.2293451229621416 0.0442553705921177 0.9647008459026224 1.0 1.0 11 O75600,P24752,P09110,P55084,O15269,Q9BWD1,P42765,O15270,P22307,P40939 10 +Histone h3 methyl lysine 4 demethylase activity 0.3989523021781033 0.0431480152616628 0.9655835442710492 1.0 1.0 3 Q8IUF8,O60341 2 +Sodium channel regulator activity 0.3938809261300896 0.0426213740784739 0.9660033569197076 1.0 1.0 2 P23634 1 +Alkali metal ion binding 0.2725863006594304 0.0424988518664539 0.9661010270029052 1.0 1.0 6 O00764 1 +Potassium ion binding 0.2725863006594304 0.0424988518664539 0.9661010270029052 1.0 1.0 6 O00764 1 +Intramolecular transferase activity 0.2294053579021694 0.0414996986780811 0.9668975330686966 1.0 1.0 10 O60832,P18669 2 +Acetyl coa hydrolase activity 0.3952098579507329 0.0404526402484479 0.9677322637158488 1.0 1.0 3 Q9Y305 1 +L leucine transmembrane transporter activity 0.390573318632841 0.040325093374426 0.9678339484263794 1.0 1.0 2 Q01650 1 +Insulin like growth factor receptor binding 0.3939895230217763 0.0396024714062551 0.9684100570891214 1.0 1.0 3 P61981,P46108 2 +Phosphatidylinositol 3 kinase binding 0.3158020422259017 0.039020858044139 0.9688737589620564 1.0 1.0 4 P0DP25,P50570 2 +Signaling receptor complex adaptor activity 0.2515445863299566 0.0386434910286194 0.9691746273447728 1.0 1.0 7 Q9UN86,O60271 2 +Rna polymerase activity 0.2043177380632721 0.0354089415042027 0.9717536548950064 1.0 1.0 19 P49642,O14802,P24928,Q9BWH6,O15160,Q13503 6 +Omega peptidase activity 0.1936675213432272 0.0349796912091356 0.9720959350289626 1.0 1.0 28 Q99496,Q9UPT9,P40818 3 +Very long chain fatty acid coa ligase activity 0.3868210642404137 0.0348857143341841 0.9721708719900282 1.0 1.0 3 Q4G176,O60488 2 +Acetyl coa c acyltransferase activity 0.2291551628934282 0.0317118535958394 0.9747018418394428 1.0 1.0 8 P24752,P09110,P55084,Q9BWD1,P42765,P22307,P40939 7 +Rdna binding 0.3758826926061053 0.0285579656709761 0.977217136934048 1.0 1.0 3 P42345 1 +Magnesium ion binding 0.1865220756239307 0.0280771919238956 0.9776005851088452 1.0 1.0 79 Q14249,Q96GD0,O43837,Q13572,P09104,O95747,P48735,P39748,P49642,Q96DE0,Q13043,P06733,P34913,O00764,Q9Y5S2,O75874,P29401,P13995,Q96SB4,Q9UBT2 20 +4 iron 4 sulfur cluster binding 0.1944521497919527 0.0268769945397217 0.9785578425857228 1.0 1.0 25 Q9Y5Y2,P28340,Q5VV42,Q06203,P21399,P61221,Q9H9T3,P78549,P49821,P49643,Q9UMS0,O75306,P28331,Q16134,Q99798,Q8TB37,Q9BX63,P21912,Q07864,O75251,P18074,Q6FI81,Q96SZ6,O00217 24 +Peptide n acetyltransferase activity 0.2016260912249602 0.0259103835999644 0.9793288179130342 1.0 1.0 14 Q6ZRS2,Q9UPT9 2 +Mitochondrion targeting sequence binding 0.3672456575682325 0.0242506979728919 0.9806526388694048 1.0 1.0 3 Q9Y584,Q15388 2 +3 5 dna helicase activity 0.2127071823204384 0.0220453128178109 0.9824118099072734 1.0 1.0 10 P33993,Q8N3C0,P19447,P46063,P49736,Q14191,Q14566,P54132,P33992 9 +Small molecule sensor activity 0.2714482758620729 0.0213211393151865 0.9829894809362092 1.0 1.0 5 P54727,Q9BUP0,O75306,Q99497 4 +Telomerase rna binding 0.210002763194246 0.0207781887581478 0.9834225968326956 1.0 1.0 11 P07910,Q01780,Q96HR8,Q9NPE3,O60832,Q9H2U1,O95453,Q9NY12,Q9NX24,Q00839 10 +Phosphatidylinositol phosphate binding 0.1855190361777717 0.017996381637439 0.9856417399797064 1.0 1.0 39 O60493,Q9H0H5,O75146,Q9NS86,O00291,P22059,P46940,O95219,O43795 9 +Protein disulfide reductase nad p activity 0.2436534216335507 0.0157998700491478 0.9873940521101195 1.0 1.0 6 P00558,P00390,P35754,Q16881,Q6DKJ4 5 +Alpha glucosidase activity 0.3376592120329885 0.0134338920167669 0.9892816273591094 1.0 1.0 3 P35573 1 +Nucleotide diphosphatase activity 0.2724765581908503 0.0128310635627321 0.9897625733938756 1.0 1.0 4 Q9BW91,P41250,Q9BQG2 3 +Tumor necrosis factor receptor binding 0.3291976840363891 0.0112804070433878 0.9909997282580514 1.0 1.0 3 Q12931,P42224 2 +Phosphatidylglycerol binding 0.247863247863242 0.0028075409407744 0.9977599093723736 1.0 1.0 3 Q00169,Q9UJZ1 2 +Enoyl coa hydratase activity 0.2166114790286943 0.0015535524739365 0.9987604449652652 1.0 1.0 6 P55084,P51659,P42126,Q9NTX5,P40939 5 +Protein phosphatase regulator activity 0.1784562880412896 0.0005968194717283 0.9995238069861908 1.0 1.0 25 Q96QC0,Q15435 2 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e02ec37b7c958a41d511ae38466ad600a3b76227 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5alpha androstane 3beta 17beta diol dehydrogenase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Angiotensin receptor binding", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Bile acid transmembrane transporter activity", "Bioactive lipid receptor activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Camp response element binding", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide 1 phosphate binding", "Ceramide 1 phosphate transfer activity", "Ceramide binding", "Cgmp binding", "Channel activator activity", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Collagen receptor activity", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Corticotropin releasing hormone receptor binding", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidine deaminase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxycytidine deaminase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix protein binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction hemi channel activity", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophosphodiester phosphodiesterase activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hmg box domain binding", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Ige binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Microtubule severing atpase activity", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin light chain binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosamine synthase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Narrow pore channel activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neuregulin binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neuropeptide hormone activity", "Neuropeptide receptor activity", "Neuropeptide receptor binding", "Neurotransmitter binding", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opioid receptor binding", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidic acid transfer activity", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine sterol o acyltransferase activator activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine 1 phosphate receptor activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Thyroid hormone transmembrane transporter activity", "Titin binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type 5 metabotropic glutamate receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Wnt protein binding", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "ALYREF", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP4M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOC1", "APOL2", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL8B", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC7", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPH", "CENPV", "CEP131", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMMD6", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM129B", "FAM173A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNBP1", "FNDC3A", "FNTA", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GAL", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GID4", "GID8", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLPH3L", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPRASP2", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRGQ", "IRS4", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KNOP1", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON1A", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MPV17", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTF2", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFS1", "NFU1", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAWR", "PAX6", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDRG1", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN2", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTF1", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE2", "TAB1", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2IP", "TES", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM115", "TMEM165", "TMEM192", "TMEM201", "TMEM206", "TMEM30A", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC26", "TTC4", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMP1", "VPS16", "VPS18", "VPS25", "VPS28", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS4A", "VPS4B", "VPS50", "VPS72", "VRK1", "VRK2", "VTA1", "VWA8", "WARS", "WARS2", "WASF2", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WRN", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFPL1", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["AAK1", "AARSD1", "ABCB6", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABI1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACO1", "ACO2", "ACOT9", "ACSF3", "ACSL4", "ACTN1", "ACTN4", "ACTR8", "ADAM17", "ADD1", "ADNP", "AFDN", "AFG3L2", "AGL", "AHNAK", "AIMP1", "AK3", "AK4", "AKAP12", "AKAP13", "AKAP17A", "AKAP8L", "ALDH4A1", "ALKBH5", "ALYREF", "ANKHD1", "ANKRD17", "ANXA1", "ARFGAP1", "ARHGAP1", "ARHGAP10", "ARHGEF1", "ARHGEF2", "ARID1A", "ARL6IP4", "ARPC4", "ASCC2", "ASCC3", "ATAD5", "ATF7", "ATG3", "ATP1B1", "ATP2B1", "ATP2B4", "ATP6V1E1", "ATPIF1", "ATXN2L", "B3GAT3", "BAIAP2", "BASP1", "BAZ1B", "BAZ2A", "BCAS3", "BCLAF1", "BCR", "BICD2", "BIRC6", "BLM", "BMS1", "BOP1", "BPTF", "BRD2", "BRD3", "BRD4", "BRIP1", "BTF3", "BUD23", "BUD31", "C1QBP", "C1orf35", "CADM1", "CALCOCO1", "CALD1", "CALM3", "CAMK2G", "CAPRIN1", "CAPZA2", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCDC124", "CCDC137", "CCDC6", "CCDC86", "CCT2", "CCT4", "CD2AP", "CD2BP2", "CDC20", "CDC37", "CDC42BPB", "CDC5L", "CDC7", "CDC73", "CDH2", "CDK1", "CDK4", "CDK5RAP1", "CDK5RAP2", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CELF2", "CEP131", "CEP250", "CEP290", "CFL2", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD4", "CHD7", "CHD8", "CHMP1A", "CHMP2B", "CHMP4B", "CHMP5", "CHTF18", "CHTOP", "CIAPIN1", "CKAP5", "CLASP1", "CLINT1", "CLPB", "CLPX", "CLTA", "CNOT4", "CORO1C", "CPSF7", "CRK", "CRYZ", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CTBP2", "CTNNA1", "CTTN", "CTU2", "CUTA", "CWC15", "CWC27", "DAXX", "DBNL", "DCAF1", "DCAF13", "DCP1B", "DCTN1", "DCTN2", "DDI2", "DDX1", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX5", "DDX50", "DDX54", "DDX56", "DENND4C", "DHFR", "DHRS7B", "DHX30", "DHX36", "DHX37", "DIAPH1", "DIDO1", "DKC1", "DLAT", "DLD", "DLGAP5", "DMAP1", 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0.5946122252326792 8.956331399455076 8.147743731837105 0.8540328943632708 0.3189032933670377 1.0 0.0627348303600114 1.3390789292949608e-05 0.000656024078174 0.0002793575176261 +Aplasia hypoplasia of the thumb 17 47 3.6359189104545737 0.0002769914616449 15.366504854368932 46.26456310679612 -0.5825781705135089 0.523227357541886 6.586920285832992 4.461312288261849 0.9568361188142324 0.337035999357659 1.0 0.4047844567784328 0.0839971460237413 0.256792622330016 4.477184029965852e-05 +Aplasia of the fingers 10 26 3.4372643297447496 0.0005876218369922 11.563106796116504 27.52912621359223 -0.6857325111479152 0.4414775036638273 5.029852442222966 2.297450299195613 1.1591251161846992 0.3512478886867645 1.0 0.2412174988663298 0.0174347284732116 0.0480412569509487 6.684613787485207e-05 +Short thumb 16 43 3.430388362400199 0.000602717927977 14.067961165048544 40.980582524271846 -0.6219695164724948 0.5043859104275452 6.0555873836976915 3.678804635226043 0.976747061268356 0.342590755319747 1.0 0.3394178268581344 0.0493235058567373 0.1508588620289784 1.1123283139016547e-05 +Acute leukemia 24 50 3.429210891092464 0.0006053389674587 17.990291262135923 45.95145631067961 -0.7182027726172646 0.4725613598893733 7.413573415631141 3.981458582261782 1.0745726377594105 0.3501093912531572 1.0 1.0 0.0104196950872655 0.0012844153930112 0.0002798090678235 +Leukemia 26 60 3.413220383717185 0.0006420000220468 21.216019417475728 57.10679611650485 -0.7215009274390324 0.485477362858576 8.622303190580958 5.90854674912426 1.0087295888092915 0.3471830662598253 1.0 1.0 0.0309622376784825 0.0097342185306864 0.0059692118944776 +Abnormality of the musculature of the hand 14 36 3.3787838053684607 0.0007280723954994 10.74271844660194 36.449029126213595 -0.0880159446727089 0.6015274987289935 5.314554150061091 3.317330782937316 0.9057022183259636 0.3237164664546611 1.0 0.3058671484100957 0.0359624367366125 0.0094398563907577 5.1052272328632354e-05 +Abnormal thrombosis 8 29 3.351868924997905 0.000802680123217 6.691747572815534 25.466019417475728 -0.757625577408351 0.3782035189375335 3.458439775947144 2.3742777500904184 1.1342208220533108 0.2982874919307307 1.0 0.0437266531990119 0.0043894701524644 0.0002422075599845 0.0054856561315088 +Sprengel anomaly 11 31 3.328217552706212 0.0008740358311136 11.533980582524272 30.429611650485437 -0.4920025967395243 0.4982433286216099 4.837285473993086 2.0532703832326566 1.0278472353277517 0.3381740299772887 1.0 1.0 0.0663348012473392 0.0038307885014085 6.056248534102103e-07 +Triangular shaped phalanges of the hand 24 71 3.3118602303446623 0.0009267783629813 20.388349514563107 64.63592233009709 -0.5098426235420919 0.5697757378378921 7.478425941162433 7.507502452969698 0.807981304483844 0.3170928269699922 1.0 1.0 0.2645290188088941 0.4626226261413173 0.0002065239344139 +Venous thrombosis 4 16 3.2687313850892488 0.0010803080700967 3.7864077669902914 14.145631067961164 0.190717814815797 0.4728350350554371 2.226933480580407 1.4773879271166803 1.1211064658620755 0.3148666674204384 1.0 0.0171096007657598 0.0074499229745329 0.0031029735300829 0.0476655926672988 +Acute myeloid leukemia 19 36 3.264436026700998 0.0010968222896665 15.194174757281552 33.95873786407767 -0.7804732873922284 0.4222952622430566 6.1214381399715805 2.1351761163401988 1.2186997725189328 0.3545674292175134 1.0 1.0 0.1138374922433585 0.0145337808063677 0.0005033193877358 +Abnormal reticulocyte morphology 10 34 3.129394014796412 0.0017516725074893 11.783980582524272 32.609223300970875 -0.486684315863186 0.5157232990779249 5.548063221898798 2.412590836086734 1.0009510537562814 0.3365214807493393 1.0 1.0 0.0981876870196897 0.0101284091234414 4.694175613051286e-05 +Abnormality of the ovary 21 75 3.1003476254020046 0.0019329363912656 13.131067961165048 60.98543689320388 0.0189933286617668 0.7395958825430006 5.819477324913906 8.053810625152751 0.6409320709274551 0.2867048678337134 1.0 0.0003289469904772 0.000107271875067 0.0027114476255096 0.0253263094269786 +Hypermetropia 22 58 3.04266157999559 0.0023449588681196 13.29126213592233 50.366504854368934 -0.289904142732946 0.7008985269469339 6.6673833937785725 6.356645052828287 0.6243541058326253 0.2865107793616068 1.0 0.554139718163406 0.214913215246426 0.0473221562185429 0.0132905663378733 +Increased mean corpuscular volume 11 24 3.0411533178624666 0.0023567379157367 10.783980582524272 22.774271844660195 -0.6079636013252522 0.4190083759260389 4.852127516514396 1.5903282325562635 1.2358851566129716 0.3506886945191059 1.0 1.0 0.0390334649397651 0.0009973173465154 1.6907281900341769e-06 +Coarctation of aorta 13 36 3.0310402699781784 0.0024371274128269 12.71359223300971 37.88106796116505 -0.4389521275232437 0.5081112337364881 6.155785794384616 3.4798910296021557 1.0158031069153757 0.331905283681996 1.0 1.0 0.2316260817282189 0.0780876886618215 0.005404303083764 +Sarcoma 28 62 2.963669001596637 0.0030399508247151 13.49271844660194 59.24757281553398 0.2024053329324482 0.5878401261352646 7.66928341789692 5.604858236953758 0.9869836607136444 0.3372231979111714 1.0 0.4769824301569347 0.0396920237566944 0.0421567666761504 0.000615643272746 +Abnormal mean corpuscular volume 11 26 2.963147660482714 0.0030451045449211 11.3252427184466 24.606796116504853 -0.6492179915325068 0.4154753877147342 4.984543458008674 1.854082985120427 1.2183247523686689 0.3463753094478407 1.0 1.0 0.0609936469852355 0.0031029735300829 1.9764214869406968e-05 +Persistence of hemoglobin f 8 21 2.918169636791289 0.0035209274626593 9.99514563106796 20.521844660194176 -0.5746459483062162 0.4024883106854605 4.363904874706898 1.4011120739722107 1.3072723321569808 0.3541603521194014 1.0 1.0 0.0228441699597423 0.0025472603414639 9.80310591995041e-07 +Abnormality of the curvature of the cornea 26 82 2.889615835990944 0.0038571287139732 21.66747572815534 70.60194174757281 -0.6731890605488073 0.5348757564736094 8.426933844311415 8.667918536972815 0.719312491713642 0.3219325605243275 1.0 0.3172349169334806 0.0787520716375872 0.2134462314161423 0.0629622971047154 +Abnormal ovarian morphology 16 35 2.885318611275222 0.0039101771555187 7.20873786407767 27.8495145631068 -0.066971010364278 0.7500485496422341 3.53692331869843 3.523385777510966 0.5298336527091101 0.2459583431786003 1.0 0.0001686598950704 0.0039627540968649 0.0476524659734338 0.0768810099666097 +Malignant genitourinary tract tumor 9 21 2.881555082434532 0.0039571806174356 9.434466019417476 20.77912621359223 -0.5417548861099344 0.4142718887051287 4.1516257730586625 1.3301037311151485 1.2853519506961442 0.3527062543070391 1.0 1.0 0.0246740936940832 0.022497237178051 1.5611785984141917e-05 +Abnormality of the zygomatic bone 27 76 2.877880479030668 0.0040035679302228 16.924757281553397 72.50728155339806 -0.2384253196660508 0.7398753587779542 8.67043121005364 7.349621573267719 0.5490743089615345 0.2672491456706462 1.0 0.6025890703102443 0.547752308120729 0.4816129562427582 0.1968508272268933 +Attention deficit hyperactivity disorder 35 106 2.8630746654932984 0.0041955168347185 29.609223300970875 96.83009708737865 -0.5877048595374816 0.5674203060639718 11.606209100649563 10.744168298093552 0.75639272983687 0.3168146858194288 1.0 0.3852166760795645 0.2752116000688604 0.2215120997759655 0.0067923245026733 +Normochromic anemia 11 24 2.8555435415254355 0.0042963231399233 9.902912621359222 22.987864077669904 -0.7652454444739983 0.3820343113751064 4.493284229505436 1.4405191556643042 1.309348266068613 0.3490551163867025 1.0 1.0 0.0368247433715485 0.0395166683685705 8.789062803877673e-05 +Abnormality of the thenar eminence 7 18 2.8470864441189625 0.0044121379671633 8.70388349514563 18.186893203883496 -0.5329823744436845 0.3958429743656864 3.804657909940043 1.1000984326005212 1.324691754247351 0.3505441151203373 1.0 1.0 0.0285062952815799 0.0276080433055301 2.939233273218525e-05 +Abnormality of the musculature of the upper limbs 27 76 2.8289334484350745 0.0046703409814474 16.381067961165048 72.26699029126213 0.1134430598291996 0.7383355073238089 6.468214353104833 6.45684536803398 0.6573078160293058 0.2970927366827226 1.0 0.2062582491875952 0.0886167389302649 0.1301905254184859 0.0002621872939711 +Erythroid hypoplasia 9 19 2.816364835501186 0.0048570475747808 9.390776699029129 19.1626213592233 -0.5527639828673522 0.3938582487298333 3.9957759709887206 1.0928989339971622 1.3343610146308624 0.3526294909242743 1.0 1.0 0.0228441699597423 0.0201545454959308 1.1085160867237355e-05 +Breast carcinoma 4 26 2.813630308004627 0.0048985527896314 5.269417475728155 21.303398058252423 0.0458449363367184 0.5512715013731206 3.6487445174839737 3.8323720894298465 0.9809579775350368 0.3254016536425757 1.0 0.2597451867723493 0.0218582842409203 0.0166068511726292 0.1753897866922502 +Small face 20 46 2.7889620851228094 0.0052877254994458 12.322815533980584 40.11165048543689 -0.4765596674787939 0.5961434803545566 5.099511097349598 5.905169710917102 0.6538213649018235 0.2905499509007266 1.0 0.4999158516222215 0.1582334891284429 0.2598032830985489 0.0190002211904817 +Abnormal scapula morphology 21 54 2.788852003617225 0.0052895230563203 13.060679611650484 51.39563106796116 0.0715702441844552 0.6973620722043212 5.3023815426244925 4.550288621999796 0.7178789707494411 0.30435988500742 1.0 0.4364495014109603 0.1053672202985524 0.0238605378340429 0.0001514998674623 +Reticulocytopenia 7 19 2.784814652691064 0.0053558328290528 9.080097087378642 20.3495145631068 -0.5425157493239673 0.4273831624263773 4.101964008671714 1.5372951777001542 1.2418683534424684 0.3493223082114023 1.0 1.0 0.0305060181117638 0.0303754901318735 3.941061696608172e-05 +Autism 17 53 2.723771782080316 0.0064541087927589 11.1626213592233 44.478155339805824 -0.0978772554705085 0.7431580252381519 5.39194481209064 6.254474786075642 0.5896679157097336 0.264584973855492 1.0 0.502402347983314 0.4038065527295172 0.4560033857541423 0.381669177692727 +Pure red cell aplasia 7 20 2.717876020110043 0.006570245224083 9.682038834951456 20.15776699029126 -0.6022526598961478 0.4049157755999357 4.214902792697585 1.1002483674054329 1.2808463277930804 0.3519742047774726 1.0 1.0 0.0210734332562196 0.0179536348510701 7.716877441905804e-06 +Neoplasm of the skeletal system 12 45 2.7089767781971648 0.0067491063380513 11.604368932038836 41.66990291262136 -0.0291078540482429 0.5465161876003419 6.690543996618306 3.3851140420896724 1.0327180982767117 0.3311582077825383 1.0 0.3394178268581344 0.0013732996273827 0.0169427644497248 0.0007222870346109 +Absent thumb 8 23 2.7072219576659404 0.0067848878107119 10.9126213592233 24.99757281553398 -0.6715988313825342 0.4253858781249786 4.7833789822362105 1.9576818895367625 1.2148477872836383 0.3497100090215405 1.0 1.0 0.0690620672163432 0.0926724515796587 0.0002221540307242 +Webbed neck 10 36 2.6851409052973563 0.0072499234340628 11.08495145631068 36.04854368932039 -0.2431615392649357 0.5780481631735521 5.974871875587152 3.215945227208002 0.905902872421312 0.3211526050262056 1.0 0.3713777336871285 0.0647665856554279 0.0809133849800328 0.0058601021721165 +Osteosarcoma 8 25 2.684879319269624 0.0072555999191634 7.810679611650485 24.50485436893204 -0.0838667199897112 0.537481976720288 4.8958157807955995 1.9638667346862224 1.0473835773003686 0.3327269107782364 1.0 1.0 0.0412914524019695 0.0462975654587087 1.950787636666492e-05 +Hypoventilation 7 16 2.683641681564907 0.0072825110931753 3.800970873786408 12.592233009708735 0.1535286707905372 0.6533636513487544 2.208588493829032 1.7663900612885866 0.7112783434753855 0.2846648147880792 1.0 0.0100088432903632 0.0368247433715485 0.0008584458110555 0.0033809375709235 +Pointed chin 17 37 2.682214212986338 0.0073136611452893 10.026699029126211 31.961165048543688 -0.4388193704760994 0.6056159251429143 4.25769044653821 3.863376284102391 0.669565532284865 0.2949920838635459 1.0 1.0 0.2280025569563264 0.0253281533053532 0.0348948982813875 +Narrow face 18 41 2.6562338643046925 0.0079018794323417 10.531553398058252 36.101941747572816 -0.3336005024819824 0.6600674508169715 4.646898382496193 5.733930361860432 0.5990102777739584 0.2741481380048506 1.0 0.4475497772550058 0.3296925469859509 0.3395639239693369 0.0320582801012716 +Glioma 4 14 2.6532743714370337 0.0079715044773989 4.390776699029126 13.74757281553398 -0.1545508609455253 0.4389667761549956 2.91634369747243 2.676646382387555 1.1838681266493505 0.3197424323829116 1.0 0.0195557545343205 0.0008752645247723 0.0042371428862997 0.0614446561434308 +Adenocarcinoma of the colon 7 21 2.626279591275173 0.0086323878594152 9.50485436893204 20.58009708737864 -0.5385965908043259 0.4099332106587272 4.098007534825994 1.3513359051095024 1.3067136508964234 0.352270731481182 1.0 1.0 0.0305060181117638 0.0303754901318735 3.941061696608172e-05 +Gastrointestinal atresia 8 17 2.580871415573473 0.0098551281342098 6.038834951456311 15.050970873786408 -0.4400882795806481 0.5884313155471691 3.1742970480813555 2.2522532469667023 0.7528159957032654 0.3120097087465301 1.0 0.0296703391700837 0.1012658374302196 0.0454498648641323 0.0501645149458417 +Genital neoplasm 7 46 2.58064473086409 0.0098616009592484 9.099514563106796 38.58495145631068 0.0026076846207917 0.6639856591297739 4.972965726190518 5.7732280303871075 0.7680778103954238 0.2906701037451463 1.0 0.1201931014379405 0.0012374125203417 0.0102035722005359 0.0739934215258644 +Adenocarcinoma of the intestines 9 24 2.568053763946355 0.0102271292644338 9.817961165048544 23.133495145631063 -0.4723450275482979 0.4508190526442003 4.3925541277805715 1.8139546502813697 1.2296228934527935 0.3539411393556459 1.0 1.0 0.0483495219963649 0.0574660247750297 0.0002718910108126 +Aplasia hypoplasia of the ovary 3 18 2.563861127811182 0.0103514952723333 4.446601941747573 12.895631067961164 -0.4761330129896438 0.5913666679592741 2.430502586324925 2.2309126391893916 0.6707559620575593 0.2940662588110445 1.0 0.0001451753331012 0.0020253160845859 0.0454498648641323 0.2796617582086531 +Narrow palpebral fissure 4 16 2.562504611277685 0.0103920207633292 4.779126213592233 15.480582524271844 -0.1590904473701882 0.613883761617405 2.9016652757373036 2.5403752590477606 0.7766381591726289 0.2906673112866563 1.0 1.0 1.0 0.0831770088647685 0.1466332856037892 +Abnormality of the forearm 19 52 2.520386188818444 0.0117226140811079 12.37621359223301 47.37135922330097 -0.289579250497952 0.6522041178739908 5.540382836392792 6.413006738969281 0.6919169590641271 0.3021258252716989 1.0 0.204463696732403 0.2355771406845026 0.607872099121274 0.1303430247223279 +Developmental glaucoma 9 31 2.515990764340357 0.011869829320988 11.04611650485437 26.973300970873787 -0.6310191636358051 0.4273073149229679 4.892565140734412 2.6707269249166576 1.1701619605888354 0.3467473976847871 1.0 1.0 0.0951370618475993 0.1403126473979322 0.0009404572232915 +Astrocytoma 3 9 2.514783176954374 0.0119105608685774 3.063106796116505 8.995145631067961 -0.0406188385045949 0.4101166468994238 2.099675901539857 2.070358471881757 1.2750952497401025 0.3317381378473951 1.0 0.0060718409625537 7.961405550860943e-05 0.0025472603414639 0.0272826327042602 +Abnormality of dental eruption 32 58 2.4831922442504264 0.0130210794269711 16.37621359223301 58.213592233009706 -0.5229779249797751 0.5783949895873435 7.644194270913433 7.096971165026756 0.7330801621594781 0.3100752514967566 1.0 0.5800983581755315 0.514804159387793 0.4289447376901218 0.04670294636798 +Partial duplication of the phalanx of hand 7 20 2.4630110407446706 0.0137775673207585 8.631067961165048 20.58252427184466 -0.4012090744680646 0.4761024817004221 4.063190891243266 1.6281758918641962 1.159132332873358 0.3522167351772669 1.0 1.0 0.0412914524019695 0.0462975654587087 0.0001419239292943 +Nasogastric tube feeding 10 29 2.459025983912125 0.0139314534313206 6.274271844660194 24.924757281553397 -0.2017983562148376 0.6842396558909075 3.2193315056974496 3.227110386389366 0.6504518910971607 0.2711215318475037 1.0 1.0 0.4473868461248688 0.4349027977407559 0.0259419504317075 +Triphalangeal thumb 7 24 2.4360303792829523 0.0148494373475498 9.701456310679612 23.740291262135923 -0.5086159584603737 0.4625380781014795 4.415407469518261 2.3447996400672646 1.1452290636928404 0.3457457067846529 1.0 1.0 0.1138374922433585 0.1757490259102167 0.0074744155515412 +Duplication of hand bones 16 66 2.435828702543444 0.0148577186346869 13.0 56.39320388349515 0.2378640054223706 0.6719363973824695 5.036758088178839 6.614250020022192 0.7270653331373877 0.3083618448816323 1.0 0.0635443329647364 0.0100892062383424 0.1759088128196933 0.0203361523901453 +Nevus 13 34 2.4357588004021635 0.0148605899187279 6.805825242718447 30.490291262135923 -0.000293037983055 0.7303357423577612 3.3726721635608095 2.9653996460506695 0.6130219638634058 0.2674754281932021 1.0 0.4135892767062017 0.6570328218304677 0.7472226666145574 0.2738776042777909 +Duplication of thumb phalanx 7 23 2.4349664789766545 0.0148931693234817 9.140776699029129 23.70145631067961 -0.44056110047929 0.50635993136825 4.430650895512268 2.4096685941282745 1.0637223560907465 0.3466324791221831 1.0 1.0 0.0746250944081647 0.1025929503981289 0.0015279037069893 +Gonadal neoplasm 6 32 2.417661834017744 0.0156205861519929 6.218446601941747 25.74271844660194 0.0706966967021421 0.6037062367826098 3.687534698150144 3.9322935312452594 0.896989985626744 0.3132109357694278 1.0 0.0623838765899965 0.0013015424048323 0.0160511047553481 0.0486758951877882 +Pierre robin sequence 3 8 2.417321673918788 0.01563519302054 2.6723300970873787 6.283980582524272 -0.3758466821719998 0.5496110164350452 1.633065913974518 1.3845316335436888 0.802625676031953 0.2930463569389501 1.0 1.0 0.1459927402947744 0.0573320310906022 0.0063533232968262 +Ovarian neoplasm 6 26 2.3987542440675127 0.0164509515660506 5.800970873786408 20.75485436893204 -0.0222415819970231 0.5296820866885116 3.7943748642961137 3.1322935435347152 1.0136090000570463 0.3142589571986427 1.0 0.0348230103466341 0.0027897058150509 0.0155472441014247 0.0259419504317075 +Delayed eruption of teeth 28 49 2.390084127559834 0.0168445138594728 12.516990291262136 47.699029126213595 -0.30634352027794 0.6942812291421392 6.82280603592021 5.769159639054829 0.6229283662604544 0.2801659126707924 1.0 0.4949062745628336 0.3934300020422008 0.2505311226043684 0.0737741172490755 +Low anterior hairline 21 57 2.3877373920040155 0.0169524503425597 18.446601941747577 54.06553398058252 -0.6343008075695392 0.5056574991998704 7.336870785233956 4.254988671942604 0.8983125562610532 0.3281073309945158 1.0 1.0 0.0915328142013738 0.1295382735517929 0.0024128096097456 +Abnormal female reproductive system physiology 20 70 2.383383640922399 0.0171543066174009 15.548543689320388 63.41019417475728 -0.2797132113837802 0.7059971382397325 6.541508452231451 7.00826093417757 0.5732781882849631 0.2730834819506468 1.0 0.2625291279015625 0.1385003630388192 0.1262842990480492 0.0206886812564786 +Cone shaped epiphysis 6 16 2.3816400030848723 0.017235737685298 3.2063106796116503 11.87135922330097 0.0642421494677637 0.5491292316029612 1.8258284409306336 3.3100985667263836 0.8697998682944144 0.2760577132687285 1.0 0.2597451867723493 0.1202677732034906 0.1880735443370416 0.0281223334511535 +Aplasia hypoplasia involving forearm bones 6 22 2.375800817032391 0.017510912493575 5.213592233009709 19.864077669902912 -0.124319310840589 0.604024927530565 2.670953015027288 3.677664264253784 0.7981540536336666 0.2932733817175926 1.0 0.0584635742500571 0.0437228444640497 0.1329615522764283 0.094428031243587 +Thrombocytosis 12 30 2.3755795291312145 0.017521416127985 12.104368932038836 29.483009708737864 -0.6114320416187982 0.4489963761256846 5.412703534575817 1.5223903885177978 1.1306447050012625 0.3463409111828631 1.0 1.0 0.0718258186813318 0.0975810446671989 0.0013172325096431 +Abnormal number of erythroid precursors 9 25 2.3746515956440635 0.0175655215138481 11.37621359223301 24.8495145631068 -0.6810034553636383 0.404010099505361 4.855356088949075 1.4419763801310608 1.2601742725866991 0.3474129076274532 1.0 1.0 0.0483495219963649 0.0574660247750297 0.0002718910108126 +Aplasia hypoplasia of the fibula 3 7 2.356430741392861 0.0184515080598646 3.400485436893204 7.029126213592233 -0.7908900814310158 0.4000497160034938 1.6227448151896249 1.0493299820621709 0.8790163322528384 0.3017623193974356 1.0 0.0937235599037543 0.179062604831997 0.3916284783790085 0.0144964406909979 +Abnormality of the parathyroid morphology 2 5 2.3523977154507074 0.0186528190192563 1.9951456310679612 5.54126213592233 0.174968201326553 0.3509598237346392 1.2385301843824976 1.1216087437262623 1.374717808134014 0.307204091695738 1.0 0.0030581061915538 0.0005633424812776 0.0076785979426991 0.0470360579614364 +Myelodysplasia 23 48 2.3356064412498263 0.0195117625750211 17.898058252427184 44.47572815533981 -0.8282210266679523 0.433801034774629 7.629102182636664 4.415538890451626 1.1327204412874183 0.3577517938656668 1.0 1.0 0.2280025569563264 0.1891451622193602 0.0348948982813875 +Short long bone 12 42 2.334007916846801 0.0195953073799739 8.308252427184467 34.19660194174757 -0.0378013390730227 0.67126826940319 3.594039004165784 6.643683627515725 0.6507460925720548 0.2694429270638558 1.0 0.1778097782829715 0.1971826376931648 0.0890875570781516 0.0411321898520915 +Scapular winging 10 25 2.3150756333894544 0.0206087932671479 6.038834951456311 23.66504854368932 0.1046530493618865 0.695517797270795 2.6945552079843313 2.4314767871759644 0.611395371052464 0.2620752989681316 1.0 0.2560754722464486 0.4473868461248688 0.4349027977407559 0.0709528715803979 +Aplasia hypoplasia of fingers 28 98 2.31459895651558 0.0206348900406387 21.0 91.03398058252426 -0.1996105763894913 0.7167648417460635 9.42085066140346 9.599949973555518 0.6093711042259652 0.2847960073845145 1.0 0.7161763490636175 0.4535392395742119 0.4270906940515658 0.0002551835219573 +Pulmonic stenosis 12 34 2.3014070773891744 0.0213686322545862 9.29126213592233 29.34223300970874 -0.3793332696580274 0.6334738954660988 4.5263651976125985 3.248130584693454 0.6477010715623709 0.290422724035822 1.0 0.3837329617083285 0.6211264656735884 0.697430154979878 0.3437117415394648 +Early onset of sexual maturation 16 45 2.300792656111572 0.021403353759366 9.75485436893204 42.38106796116505 0.0255629521708843 0.6824039617296911 4.685300368375371 5.347436626189173 0.732246597870455 0.2980522101053944 1.0 0.4923830768256354 0.3899534463534457 0.8536939354591431 0.1315853590823689 +Abnormal tracheal morphology 15 37 2.288711656125692 0.0220961113274511 10.407766990291265 35.929611650485434 -0.32981714502514 0.6115343394776538 4.920113056566464 4.581770214206142 0.7440117087625703 0.2997032940859304 1.0 0.453019277017924 0.3368794793344129 0.5789646053767982 0.3848066879992622 +Abnormality of the diencephalon 21 40 2.283387837158964 0.022407533074001 7.381067961165049 30.08009708737864 0.0256588201259561 0.7242728478776345 3.8958442914154174 4.166544048844605 0.6020319096564959 0.2667422523133999 1.0 0.3491693980885609 0.2099579933724119 0.0622835211988883 0.0254395655378738 +Obsessive compulsive behavior 19 42 2.2820605949937542 0.022485763022042 9.885922330097088 40.099514563106794 -0.1793102054386582 0.7169169654437975 5.247662066007673 4.2044012719545645 0.604333994966291 0.2811500574082166 1.0 0.3587798531269947 0.5897423730476636 0.3799926711837486 0.0119671638740754 +Malignant neoplasm of the central nervous system 4 26 2.278739667317472 0.0226825452433814 6.453883495145631 23.82766990291262 -0.1035875416121286 0.5489059085312997 4.178110952578651 3.916843315852553 0.9853841716312314 0.3143838966418644 1.0 0.0508992589190798 0.0059312171066033 0.0349006731083518 0.2926576541582433 +Somatic mutation 7 44 2.271081797419378 0.0231420266938442 11.509708737864075 42.92718446601942 -0.2581995202596953 0.58553201799663 5.449895600017371 6.836831920820132 0.8526028389164794 0.3209615673362611 1.0 0.1569435616805101 0.0028711066178054 0.0253121022307826 0.1648711683039708 +Metrorrhagia 3 7 2.253162886409286 0.0242488805416507 2.6092233009708736 6.196601941747573 -0.4353598652222274 0.5338349809407495 1.5626751951927365 0.9915605562421584 0.8394475387201417 0.308447295759199 1.0 1.0 0.1289666473793992 0.0448845799435813 0.0280386150660574 +Abnormality of malar bones 22 65 2.2451182727016032 0.0247605408578244 13.895631067961164 63.116504854368934 -0.1779622542278173 0.7376656780939418 7.386768565785156 6.93562769136849 0.5596712473293353 0.2656691535750526 1.0 0.5451422660923099 0.4641940615408458 0.3509014680054083 0.1531831401883949 +Neoplasm by histology 50 110 2.2211088472487406 0.0263435899543416 24.1626213592233 100.4004854368932 -0.0695215913268657 0.6299759235194263 11.89763217539116 10.591363937454569 0.8403649349967283 0.3117129870709569 1.0 0.3904773594675764 0.0179849986877228 0.1365591079260328 0.0464032904950049 +Downturned corners of mouth 15 44 2.2154371227425407 0.0267300756590114 10.6626213592233 37.69660194174757 -0.2232799406833301 0.7059491161449817 5.619855656019578 3.9759822755065017 0.6001428104594595 0.2790290053924821 1.0 1.0 1.0 0.7282057855703736 0.3965115260322132 +Esophageal atresia 4 8 2.2150919864925176 0.0267537513638473 2.9733009708737863 6.54126213592233 -0.2905240252264424 0.5883439190944629 1.9262534128165505 1.50266635485167 0.7482588827963258 0.2893897609913516 1.0 0.0981765691424607 0.1871299927573601 0.0927037920539492 0.0798154053066686 +Intestinal atresia 5 11 2.2116133388061505 0.0269933929724972 4.131067961165049 9.83980582524272 -0.4728637821853745 0.5764851753677096 2.284881893496016 1.4857144864043357 0.7116879622022515 0.3086700251317368 1.0 0.0163255968864409 0.0583817580096799 0.0161470643842222 0.0435237537141962 +Abnormal hemoglobin 8 26 2.199058952888548 0.0278737307045946 10.66019417475728 24.854368932038835 -0.4940105742005687 0.4793564225003066 4.806555794232795 2.072275457709958 1.0756198594636464 0.3366187037738133 1.0 1.0 0.0483495219963649 0.0112279346109804 4.177932068990829e-05 +Neoplasm of the endocrine system 21 45 2.1898282143209253 0.0285366977046366 9.281553398058252 39.21601941747573 -0.1320464774870864 0.6293850541497769 5.5540896778915325 4.9545934046547355 0.7512360229380008 0.2880697421946374 1.0 0.1012287617298736 0.0934596512163871 0.0532250292544797 0.0879041241268644 +Gynecomastia 5 21 2.186073359745732 0.028810238667654 5.902912621359223 19.075242718446603 -0.1184543716927388 0.659401594567261 3.353058488212617 1.89190115746871 0.7144107334429693 0.2923283616121994 1.0 0.2298835505782255 0.4076874771235006 0.040508503274826 0.043045103354355 +Papillary thyroid carcinoma 7 10 2.185648172631898 0.0288413553588964 3.832524271844661 9.347087378640778 -0.4656682932254213 0.5303061873472116 2.424312621405103 1.560562589038556 0.858830542987317 0.3068842684270023 1.0 1.0 1.0 0.3606019508791212 0.2179847922025966 +Oligodactyly 4 8 2.1799415331500933 0.0292617957314036 3.674757281553398 7.016990291262136 -0.4870931505654937 0.4947004473496435 1.969683748042144 1.378476248216135 0.8730458732890882 0.3053388947380768 1.0 0.1026081339138497 0.1951188871774342 0.4211551865871433 0.0892170338783466 +Abnormality of the ulna 12 39 2.179302719895226 0.0293091873111139 10.135922330097088 35.28398058252427 -0.4011430751764371 0.6454106078075585 4.584267193642322 4.932991341208547 0.6109293812452964 0.2884213030089868 1.0 0.453019277017924 0.7017079055797242 0.8050389499663938 0.24414876474732 +Aplasia hypoplasia of the radius 6 18 2.177818546294138 0.0294195485719344 4.696601941747573 17.12621359223301 -0.1144918049467531 0.5876560420538404 2.3040041352267275 2.6746912049350664 0.8033672293258153 0.2852999355349223 1.0 0.0425713267043903 0.0279020879533615 0.0817548825121617 0.1071972712501636 +Abnormal astrocyte morphology 7 17 2.16985378592206 0.0300179242572724 3.54126213592233 16.20873786407767 0.4731534517279612 0.4675130828680874 2.35465792441142 2.5609315203013745 1.0847965639398074 0.3356447738091184 1.0 0.0187248462666395 0.0008016777344491 0.0038307885014085 0.0171255123594616 +Hematological neoplasm 25 86 2.1642658443662843 0.0304439524807775 26.759708737864077 79.80825242718447 -0.6031154527216832 0.5244672019155708 11.024818775897408 8.808624957677468 0.8852201042768985 0.3210153490192742 1.0 0.6238979592774339 0.0441976218050442 0.0534949441158986 0.057786997735188 +Prominent eyelashes 7 9 2.161728900292334 0.0306390786425234 3.8810679611650487 7.95873786407767 -0.6110995280660765 0.4737439922767813 2.126561293997625 1.0003622446919649 0.942327938966006 0.3263536001560287 1.0 1.0 1.0 1.0 0.5034522087350044 +Macrocytic anemia 9 37 2.1546963970391486 0.0311855999356294 10.618932038834952 35.41747572815534 0.0386714735659423 0.596736697300035 6.139394583324174 1.8500814563261656 0.988500669832288 0.3271589133359835 1.0 0.2145132052110039 0.0121710399777804 0.006739536005846 0.0001019601367152 +Enchondroma 2 10 2.152836434274457 0.0313315356238133 3.1674757281553396 8.941747572815533 -0.1573377930464146 0.3646828517313277 2.0225933647952545 0.7641893060648111 1.3390024615924572 0.3130810820086085 1.0 0.0711332726649859 0.0003823532959252 0.0053269286919759 0.0338099842169397 +Broad long bones 14 41 2.148241866787429 0.0316945463636639 9.240291262135925 34.310679611650485 -0.3194839809550222 0.6532009282306934 4.518358228407185 5.701778169607229 0.630724399264327 0.2853347794474247 1.0 1.0 0.7457455865111695 0.6622542980003836 0.0368742357920235 +Hand muscle weakness 4 10 2.136884339490785 0.0326074000584428 2.8058252427184467 10.820388349514564 0.4952781372617184 0.5553355274479741 1.7253577224537426 1.6697688476326478 0.7717943987196815 0.3071851204356355 1.0 0.1157751708195439 0.2186221342412543 0.022497237178051 0.0312662716526952 +Abnormality of the incisor 11 30 2.124115278490765 0.033660505231605 8.337378640776699 27.266990291262136 -0.3516750715827043 0.6446698365586601 3.987268686090488 4.281545142320817 0.6327591031487263 0.2853551328811958 1.0 1.0 1.0 0.8991665276118582 0.1611631141113973 +Limb undergrowth 15 56 2.1222588084637595 0.0338160105089422 10.648058252427184 51.10436893203884 0.3980398713744312 0.5752346762319336 4.664982243954684 7.303495661229484 0.9215304205365352 0.3350258300048305 1.0 0.2242958901844974 0.1035973042213631 0.2886534445308464 0.0323694648068961 +Cleft lip 15 59 2.118897338904483 0.034099143900991 15.259708737864075 52.779126213592235 -0.4091865870529529 0.6001388218638778 6.444161044360375 5.305451603042428 0.7480040405435838 0.3090427026044984 1.0 0.5585728030790713 0.0788102846384424 0.1111790619913866 0.0066390577033407 +Down sloping shoulders 11 27 2.116322971161937 0.0343173483518424 7.201456310679611 23.259708737864077 -0.3260767660744765 0.67170105330787 3.601603986728338 3.336766051457108 0.5932631981602491 0.275746325436455 1.0 0.2849410889163232 0.4895400608205746 0.8161698151860872 0.0468956043941571 +Neoplasm of the breast 9 34 2.110904726716924 0.0347805017331386 6.725728155339806 28.038834951456312 0.0356761006774126 0.6192223775535868 4.16469421060515 4.780974288522818 0.8421728870494568 0.3094296183049012 1.0 0.326192706464958 0.0437228444640497 0.0463723625926758 0.094428031243587 +Aplasia hypoplasia of the earlobes 3 11 2.0951149985792843 0.0361607709587099 2.45873786407767 8.728155339805825 0.2132050838552048 0.6258595323978704 1.9473024306787776 2.200812624663729 0.6819884223879101 0.2713590932373291 1.0 0.1788224008957527 0.0583817580096799 0.0741296824894279 0.1288473164062758 +Axial muscle weakness 3 6 2.086988849262451 0.0368891425195767 1.6067961165048543 4.393203883495145 0.1219938986244005 0.5216241988793556 1.117274956026295 1.1302342858698775 1.008996584628824 0.3153465460476101 1.0 0.0937235599037543 0.179062604831997 0.012195883686582 0.0144964406909979 +Central hypoventilation 4 8 2.080136910448366 0.0375129769367699 2.0485436893203883 6.529126213592233 0.265942841586456 0.6001495995491183 1.380366074821613 0.9039429344434988 0.7472961587299225 0.2835239781724759 1.0 0.0573151884822011 0.1116045715736199 0.0336123253792317 0.0182159139614431 +Duodenal atresia 2 7 2.061746128322061 0.0392319123834661 2.8033980582524274 6.859223300970874 -0.3295157506199243 0.5889553244448229 1.6859465109149023 1.04258238883808 0.7086862557865345 0.2810870725101305 1.0 0.1287528218161406 0.2414457297612108 0.0303754901318735 0.1539585868211262 +Exostoses 1 6 2.05964163699305 0.0394328126654501 1.8737864077669903 4.565533980582524 0.1227309696596917 0.3298370080715785 1.065155184012566 0.8232521681359034 1.4140930420981814 0.2989667883126048 1.0 0.066549445548378 0.0080257871552124 0.0448845799435813 0.1467539296032722 +Abnormality of the frontal hairline 29 81 2.0557743230151417 0.0398042741115616 22.196601941747577 72.96844660194175 -0.5372094815009898 0.5692482515889328 9.244399412186551 7.029858269957677 0.7665119970529438 0.321376500306521 1.0 1.0 0.0695854338921134 0.0937625737532736 0.0017681665875301 +Tracheoesophageal fistula 11 22 2.046053112371234 0.0407511454057303 7.597087378640777 19.771844660194176 -0.6016963721337217 0.5397635669194348 3.5235396013755915 2.3640477660037273 0.691056764907909 0.303106300460832 1.0 0.2849410889163232 0.1434310184114938 0.2327516588823357 0.2364098572110782 +Oral cavity bleeding 3 7 2.0457658513444894 0.0407794133134289 2.907766990291262 6.640776699029126 -0.4766187895125983 0.5241285419903859 1.6637884784570067 0.7517535349575301 0.8177819063959982 0.3047631055380783 1.0 1.0 0.1289666473793992 0.2937421672442234 0.1467539296032722 +Hypoplastic fifth fingernail 6 8 2.0401897905946083 0.0413314262146538 3.5242718446601944 6.927184466019417 -0.6547366836453326 0.4611604630528866 1.88939123187109 0.9499815199794072 0.8923477046185219 0.3136829999976535 1.0 1.0 1.0 1.0 0.4230365159515766 +Omphalocele 4 14 2.03015303211703 0.0423409863228521 3.6310679611650487 12.179611650485436 -0.056407939611392 0.5966928140321276 2.4790003123798385 1.8569658530198507 0.7860299893378973 0.286796913022982 1.0 0.0257915242502586 0.0891217330395956 0.3568501183857085 0.1013718771427775 +Restrictive behavior 4 5 2.0291457088848865 0.0424434514299552 2.3228155339805827 5.237864077669903 -0.3653661223143372 0.5439582204734962 1.4862358248734742 0.9199637503257776 0.7829473265783785 0.2877376576039206 1.0 1.0 1.0 0.0390924086837951 0.0228394808772788 +Abnormal vena cava morphology 7 11 2.021812499831061 0.043195725937795 2.941747572815534 8.339805825242719 -0.2678449614326369 0.5479717216999644 1.7084896112691166 2.237384907527555 0.8139782052098616 0.2888942130058845 1.0 1.0 0.3196260593385788 0.0697809861326579 0.0396063215160503 +Abnormal nasal base 7 12 2.019207745082893 0.0434656316663319 4.844660194174757 11.109223300970871 -0.5411885358651767 0.5468706746404361 2.676787240905726 1.3546799065335702 0.7731128784077995 0.3142626162339075 1.0 1.0 1.0 1.0 0.7277205469267596 +Abnormal tracheobronchial morphology 18 61 2.0171898330091085 0.0436757066688289 15.055825242718448 56.398058252427184 -0.3069867713525168 0.638836540346017 6.448397862925805 7.640070408135441 0.6789352626047359 0.2927048976338222 1.0 0.6494048668415231 0.6167482341115913 0.7649761210307235 0.7069460451780457 +Neck flexor weakness 1 6 2.0033992310099946 0.0451344539482359 1.1844660194174756 4.080097087378641 1.0354997229853702 0.291511322357407 0.8701921762476387 0.8651235897405047 0.9922301732116002 0.2656336426050549 1.0 0.0937235599037543 0.179062604831997 0.0852058322554232 0.2546657991273667 +Increased nuchal translucency 7 17 2.0032570133444967 0.0451497089221311 4.922330097087379 15.696601941747574 -0.0837983182675558 0.6911095448592564 3.169757947294079 1.341166028975452 0.6174035322540831 0.2673029285431494 1.0 1.0 1.0 1.0 0.2957464229501276 +Bone marrow hypercellularity 4 11 1.9944935230476468 0.0460981470959445 3.796116504854369 9.563106796116504 -0.5120426129280305 0.5350543535594355 2.042553243716528 1.408503322663391 0.7551854352072617 0.2965661087499849 1.0 1.0 0.2186221342412543 0.4627901258069825 0.3460963812051635 +Neoplasm of the colon 8 40 1.994034402325265 0.0461482950383254 14.063106796116504 37.68689320388349 -0.4260277901885612 0.5266251749476274 6.313869619426652 3.617852586564183 1.012443654803162 0.3374921931647246 1.0 0.288471198078913 0.0300946598886555 0.0888749025390611 0.0060441570275233 +Abnormal duodenum morphology 4 16 1.989547383280652 0.046640817223958 3.594660194174758 14.060679611650484 -0.0648723798196945 0.6605548366904969 2.340705775040661 2.3490769772240587 0.6717876791431909 0.2615988930159845 1.0 0.270648213584465 0.1300768221953693 0.020070400313839 0.2007884256395009 +Pulmonary hemorrhage 2 7 1.9805520515075683 0.0476415305998378 2.8859223300970873 6.953883495145631 -0.5333064364126511 0.5127668585650412 1.6052389574366306 0.9705915852002686 0.7919905296168421 0.2993467309667402 1.0 1.0 0.1543818096433915 0.3445026949300507 0.1998160014011807 +Abnormality of the hairline 33 100 1.9786081369382809 0.0478601428187523 26.929611650485437 89.74029126213593 -0.5881385847222433 0.5445849893195202 10.492364160399092 9.566985500441184 0.7770566474046292 0.3222184305811695 1.0 1.0 0.158455529589903 0.0806821380808027 0.0003010616917456 +Broad finger 14 41 1.975625876328404 0.0481971656856126 9.45388349514563 34.449029126213595 -0.389440719245925 0.627796641817922 4.493286196181538 5.422877109504025 0.6447425141069495 0.2904219909186403 1.0 1.0 0.7017079055797242 0.5789646053767982 0.0157083713558504 +Abnormality of the radial head 3 10 1.9710182725988792 0.048721785797904 3.1407766990291264 8.220873786407767 -0.6029925942498306 0.494747688766471 1.605387585491815 2.0401911231601773 0.8344450891298693 0.3107442047688399 1.0 1.0 1.0 1.0 0.5296970804404293 +Embryonal neoplasm 15 26 1.965741449401468 0.0493284842431145 8.558252427184467 23.138349514563107 -0.5749427645538212 0.5592743412687492 4.0451343005017835 3.0731826572512513 0.6765143757791289 0.297946383364417 1.0 0.2742474624411909 0.1333872493386999 0.4760351828148487 0.6204077015109344 +Urethral obstruction 10 20 1.9609627670767824 0.0498833663861755 7.463592233009709 17.09223300970874 -0.8274159022872676 0.4470899506412127 3.1555367750321737 2.1635187681805728 0.7208074206508736 0.3019493443202294 1.0 1.0 0.3776146865857887 0.6971115950162535 0.2049440017843767 +Abnormally low pitched voice 4 9 1.9606601749846164 0.0499186777033993 3.849514563106796 6.825242718446602 -0.7757426560418856 0.4172165713419536 1.8306120673288624 1.267036788195652 0.8564363110288951 0.2998245849519335 1.0 1.0 0.1027954944442906 0.0284635326710383 0.0013990642028563 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..feb49f22fe07a906f4d8f49a79f0f600e0d63595 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 4647, + "title": "Average number of proteins per term", + "value": 25.854960189369486 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9c8be901108796a6a03ed4b9bfc2d20e110e5cef --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f96a5329dc43b72755461eb13199777025cd8c75 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1624 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Neoplasm of the genitourinary tract 0.4879588853662353 4.111366400544494 3.933244439591199e-05 0.1670498343477527 0.1151926131489447 75 Q9NWH9,P62913,Q15437,P20585,P48735,O60934,Q92878,Q01844,Q9Y6D9,P61254,Q99496,P62273,P02545,P62081,P62857,P62899,O75874,P39019,Q96L73,Q92733 20 +Aplasia hypoplasia of the thumb 0.5344622603830723 3.6359189104545737 0.0002769914616449 0.72400088617004 0.1423305739593976 47 Q96ST3,Q9P2D1,Q9Y448,Q9UQE7,P61254,P18583,P62913,P62273,P62081,P62857,P46777,P62899,P39019,P21333,Q03252,Q6ZRS2,Q14683 17 +Aplasia of the fingers 0.6160517131772565 3.4372643297447496 0.0005876218369922 0.9348772477664452 0.1423305739593976 26 Q9P2D1,P61254,P18583,P62273,P62913,P02545,P62081,P62857,P62899,P39019 10 +Short thumb 0.5329209881086582 3.430388362400199 0.000602717927977 0.9392916850473378 0.1423305739593976 43 Q96ST3,Q9P2D1,Q9Y448,Q9UQE7,P61254,P62913,P62273,P62081,P62857,P46777,P62899,P39019,P21333,Q03252,Q6ZRS2,Q14683 16 +Acute leukemia 0.4998063715269469 3.429210891092464 0.0006053389674587 0.9400270671596 0.1423305739593976 50 O60832,P62913,O60934,P61011,P35658,O00165,P06748,P11274,P61254,Q14980,Q99961,P62273,P62081,P62857,P46777,P54132,P39019,P62899,P61353,Q96L73,Q5F1R6,P62263,Q01130,P62847 24 +Leukemia 0.4804853907289271 3.4132203837171855 0.0006420000220468 0.9494267336671444 0.1423305739593976 60 O60885,O60832,P62913,O60934,Q8TDP1,P61011,P35658,O00165,P06748,P11274,P61254,Q14980,Q99961,P62273,P62081,P62857,P46777,P54132,P39019,P62899,P61353,Q96L73,Q5F1R6,P62263,Q01130,P62847 26 +Abnormality of the musculature of the hand 0.5564736431902173 3.3787838053684607 0.0007280723954994 0.9661082847642796 0.1423305739593976 36 Q14203,P61254,Q8TD16,P62913,P11047,P62273,P54098,P62081,Q14315,P62857,P46777,P62899,P39019,P21333 14 +Abnormal thrombosis 0.5827624768081914 3.351868924997905 0.000802680123217 0.976044380655272 0.1423305739593976 29 Q9NWH9,Q14980,Q8NBM4,Q14315,O75874,P35579,P48735,P40818 8 +Sprengel anomaly 0.5726410614996064 3.328217552706212 0.0008740358311136 0.98280988128502 0.1423305739593976 31 P61254,P62273,P62913,Q9Y2W2,P02545,P19022,P62081,P62857,P62899,P39019,P21333 11 +Triangular shaped phalanges of the hand 0.4429216001109101 3.3118602303446623 0.0009267783629813 0.9865494594340126 0.1423305739593976 71 O60885,P55011,P62913,Q7Z6Z7,Q15233,Q9Y448,Q12830,Q15910,Q9UQE7,P61254,Q9BPU6,P62273,P62081,O75369,P62857,P46777,P62899,P39019,Q9H2P0,Q96L73,O60828,P21333,Q8N3R9,Q14683 24 +Venous thrombosis 0.7247823436236573 3.2687313850892488 0.0010803080700967 0.9934146331344984 0.1423305739593976 16 O75874,P40818,P48735,Q9NWH9 4 +Acute myeloid leukemia 0.5442498745798173 3.264436026700998 0.0010968222896665 0.9939016097777782 0.1423305739593976 36 O60832,P62913,P61011,P35658,P06748,P61254,Q99961,P62273,P62081,P62857,P46777,P54132,P39019,P62899,P61353,Q5F1R6,P62263,Q01130,P62847 19 +Abnormal reticulocyte morphology 0.5386032431431578 3.129394014796412 0.0017516725074893 0.9997104434100446 0.1423305739593976 34 P11166,P61254,P62273,P62913,Q9NP58,P62081,Q15437,P62857,P62899,P39019 10 +Abnormality of the ovary 0.4148806771421998 3.1003476254020046 0.0019329363912656 0.9998754804434952 0.1423305739593976 75 P54098,Q15437,P20585,Q13049,Q9NQ48,Q03252,P48735,P40818,Q9UIG0,O15078,Q9P2D1,O60934,Q8NFV4,O14974,Q92878,Q01844,Q15056,P02545,P54132,O75874,Q15051 21 +Hypermetropia 0.4540265048594009 3.04266157999559 0.0023449588681196 0.9999817221461912 0.1431233819203325 58 Q96ST3,P18583,Q7Z6Z7,Q92785,Q9HD42,Q9UIG0,Q7Z3K3,O75175,Q8NFV4,Q8WXI9,Q96JM3,O14974,Q92878,P25490,Q15056,Q9H2P0,Q6ZRS2,Q96L73,Q5F1R6,O14802,Q9Y366,O60828 22 +Increased mean corpuscular volume 0.595660649196816 3.0411533178624666 0.0023567379157367 0.9999826979682608 0.1431233819203325 24 Q5F1R6,P61254,Q02241,P62273,P62913,Q9NP58,P62081,P62857,P46777,P62899,P39019 11 +Coarctation of aorta 0.5197105136885398 3.0310402699781784 0.0024371274128269 0.9999881021659676 0.1431233819203325 36 Q9UBM7,P61254,O14678,P53597,P62913,P62273,P19022,P62081,P62857,P46777,P62899,P39019,Q6ZRS2 13 +Sarcoma 0.4398964760116199 2.963669001596637 0.0030399508247151 0.9999992829836986 0.1457242043401116 62 P31040,O60885,P62847,P62913,Q15437,Q12824,P48735,O60934,Q92804,Q969G3,Q6P1J9,Q9BZE9,Q01844,P61254,Q99496,P62273,P02545,P62081,P62857,P46777,Q01082,P39019,O75874,P62899,P61353,Q96JJ3,P21333,Q05655 28 +Abnormal mean corpuscular volume 0.5583340010652103 2.963147660482714 0.0030451045449211 0.99999930000293 0.1457242043401116 26 Q5F1R6,P61254,Q02241,P62273,P62913,Q9NP58,P62081,P62857,P46777,P62899,P39019 11 +Persistence of hemoglobin f 0.6169252154108497 2.918169636791289 0.0035209274626593 0.9999999238546616 0.1457242043401116 21 Q5F1R6,P61254,P62273,P62913,P62081,P62857,P62899,P39019 8 +Abnormality of the curvature of the cornea 0.385881449860839 2.8896158359909436 0.0038571287139732 0.9999999841283924 0.1457242043401116 82 O43837,P55011,Q7Z6Z7,Q9HD42,Q92974,Q9UIG0,O15078,Q7Z3K3,O75175,Q12830,Q8NFV4,Q8WXI9,O14974,P25490,P10412,Q99496,Q9BPU6,Q15056,Q9H2P0,Q96L73,Q5F1R6,Q15051,O43395,Q8N201,P21333,Q8N3R9 26 +Abnormal ovarian morphology 0.508720922501422 2.885318611275222 0.0039101771555187 0.9999999876079568 0.1459445899144724 35 Q9P2D1,O43709,Q8NFV4,Q15056,O14974,P02545,Q15437,P20585,P82650,Q15031,Q13049,Q9NQ48,Q03252,Q9UIG0,O15078,P51809 16 +Malignant genitourinary tract tumor 0.611931113616023 2.881555082434532 0.0039571806174356 0.999999990048066 0.1459445899144724 21 P61254,P62273,P62913,P62081,P62857,P46777,P54132,P39019,P62899 9 +Abnormality of the zygomatic bone 0.3963993805797551 2.877880479030668 0.0040035679302228 0.999999991984769 0.1464927572578385 76 P36543,P51608,Q9UIG0,Q15233,Q7Z3K3,O75147,O75175,Q9P2D1,O60934,O43709,Q04721,Q8NFV4,P50454,P25490,P11274,Q15056,P02545,Q14807,O75369,P54132,Q15042,Q13428,O14802,P17980,O60828,P21333,P35573 27 +Attention deficit hyperactivity disorder 0.4087485336267159 2.8630746654932984 0.0041955168347185 0.9999999967270712 0.1473171913786843 106 Q96ST3,Q9UBM7,O60885,P55011,P51608,O95319,O75179,Q7Z6Z7,Q9UIG0,Q9P2D1,O75175,O43709,O60934,Q12830,Q8NFV4,O14974,P19022,P25490,Q13409,Q9UQE7,Q9BPU6,Q15056,Q7LBC6,Q01082,Q9H2P0,Q9GZZ9,Q6ZRS2,Q96L73,P29401,P11166,P51610,Q9Y2W2,Q9BZI7,Q8N3R9,Q14683 35 +Normochromic anemia 0.5722376402402921 2.8555435415254355 0.0042963231399233 0.9999999979553208 0.1473171913786843 24 P47985,P61254,Q01130,P62273,P62913,P62081,P62857,P46777,P62899,P39019,P61353 11 +Abnormality of the thenar eminence 0.6393777323166343 2.8470864441189625 0.0044121379671633 0.9999999988091162 0.1473171913786843 18 P61254,P62273,P62913,P62081,P62857,P62899,P39019 7 +Abnormality of the musculature of the upper limbs 0.393104200967479 2.8289334484350745 0.0046703409814474 0.999999999643224 0.149002128611235 76 Q8TD16,Q14331,Q9UHD8,P62913,P54098,Q13049,P50402,O75147,Q14203,P61254,P11047,P62273,P08397,P02545,P62081,O75369,P62857,P46777,P62899,P39019,P61353,Q15149,O75190,P43243,Q14315,P55072,P21333 27 +Erythroid hypoplasia 0.6243801615987034 2.816364835501186 0.0048570475747808 0.9999999998507938 0.149002128611235 19 P61254,P62273,P62913,P62081,P62857,P46777,P62899,P39019,P61353 9 +Breast carcinoma 0.5406956746486608 2.813630308004627 0.0048985527896314 0.999999999877083 0.149002128611235 26 O75874,Q92878,Q15437,P48735 4 +Small face 0.4603805568088889 2.7889620851228094 0.0052877254994458 0.9999999999800392 0.1490332644108294 46 Q96ST3,Q9Y281,P55011,Q7Z6Z7,Q9UIG0,Q9Y4L1,Q9P2D1,O75175,Q12830,Q8NFV4,Q15056,Q9BPU6,P02545,P54132,Q96L73,Q13428,Q9BZI7,O60828,P21333,Q8N3R9 20 +Abnormal scapula morphology 0.4393545252912864 2.7888520036172255 0.0052895230563203 0.9999999999802062 0.1490332644108294 54 Q8TD16,Q14331,Q9UHD8,P62913,P54098,O75147,P19022,P61254,P11047,P62273,P02545,P62081,O75369,P62857,P46777,P62899,P39019,P61353,Q9Y2W2,P55072,P21333 21 +Reticulocytopenia 0.6199042411482796 2.7848146526910633 0.0053558328290528 0.9999999999854792 0.1490332644108294 19 P61254,P62273,P62913,P62081,P62857,P62899,P39019 7 +Autism 0.4352020319181791 2.723771782080316 0.0064541087927589 0.9999999999999144 0.1621202354591946 53 Q96ST3,Q9GZZ9,Q9P2D1,Q9UBM7,Q9UQE7,Q14683,O60885,P51608,Q8NFV4,O95319,P25490,Q15056,Q15437,Q9HCK8,Q01082,Q9UIG0,Q15233 17 +Pure red cell aplasia 0.6003956602846009 2.717876020110043 0.006570245224083 0.9999999999999504 0.1641501589049125 20 P61254,P62273,P62913,P62081,P62857,P62899,P39019 7 +Neoplasm of the skeletal system 0.4568900917868621 2.7089767781971648 0.0067491063380513 0.9999999999999784 0.1650689323838143 45 Q13428,P61254,P62273,P62913,P02545,P62081,P62899,P46777,P62857,P39019,O75874,P48735 12 +Absent thumb 0.5658531496802109 2.7072219576659404 0.0067848878107119 0.9999999999999818 0.165075254745437 23 P61254,P18583,P62273,P62913,P62081,P62857,P62899,P39019 8 +Webbed neck 0.4843095902656874 2.6851409052973563 0.0072499234340628 0.999999999999998 0.1716494108189869 36 Q9P2D1,P61254,P62273,P62913,Q9Y2W2,P02545,P62081,P62857,P62899,P39019 10 +Osteosarcoma 0.5386425196007795 2.684879319269624 0.0072555999191634 0.999999999999998 0.1716494108189869 25 P61254,P62273,P62913,P02545,P62081,P62857,P62899,P39019 8 +Hypoventilation 0.6337748165996928 2.683641681564907 0.0072825110931753 0.9999999999999982 0.1716494108189869 16 Q9Y281,Q14203,P51608,P11047,O75380,Q8N183,Q9BU61 7 +Pointed chin 0.4800567590241028 2.682214212986338 0.0073136611452893 0.9999999999999984 0.1716494108189869 37 Q7Z3K3,O75147,O14802,O43709,P36543,Q04721,Q8NFV4,Q15056,Q96JM3,P19022,Q9HCK8,Q7LBC6,Q01082,P21333,Q9UIG0,Q96L73,P25490 17 +Narrow face 0.4651464159444152 2.6562338643046925 0.0079018794323417 1.0 0.1792784053500372 41 Q96ST3,Q9Y281,Q9P2D1,O75175,Q9UIG0,P55011,Q12830,Q8NFV4,Q15056,Q9BPU6,Q9BZI7,P02545,Q7Z6Z7,P54132,O60828,Q8N3R9,Q9Y4L1,Q96L73 18 +Glioma 0.661619659674857 2.6532743714370337 0.0079715044773989 1.0 0.1792784053500372 14 O75874,P20585,P48735,Q96L73 4 +Adenocarcinoma of the colon 0.5776235636269934 2.626279591275173 0.0086323878594152 1.0 0.1792784053500372 21 P61254,P62273,P62913,P62081,P62857,P62899,P39019 7 +Gastrointestinal atresia 0.6100013484980158 2.5808714155734735 0.0098551281342098 1.0 0.1909452485734488 17 Q96ST3,Q9P2D1,P18583,O14974,Q9Y2W2,Q7LBC6,Q8NCM8,P25490 8 +Genital neoplasm 0.4418128206069036 2.58064473086409 0.0098616009592484 1.0 0.1909452485734488 46 Q9Y6D9,Q15437,P20585,O75874,Q92878,P48735,Q96L73 7 +Adenocarcinoma of the intestines 0.5367983738594676 2.568053763946355 0.0102271292644338 1.0 0.195578064575407 24 P61254,P62273,P62913,Q13043,P62081,P62857,P46777,P62899,P39019 9 +Aplasia hypoplasia of the ovary 0.5985645420040018 2.563861127811182 0.0103514952723333 1.0 0.1963078068584998 18 Q13049,Q9P2D1,O15078 3 +Narrow palpebral fissure 0.6156334224923833 2.5625046112776855 0.0103920207633292 1.0 0.1963078068584998 16 Q9H2P0,Q96DF8,Q8N201,Q8WXI9 4 +Abnormality of the forearm 0.4194995587535196 2.520386188818444 0.0117226140811079 1.0 0.2136274024898382 52 Q9UBM7,O60885,Q96AY3,Q9UIG0,Q9P2D1,O75147,O43709,Q04721,Q8NFV4,P98175,Q9UQE7,P61254,Q15056,O75369,P39019,Q6ZRS2,P21333,Q8NCM8,Q14683 19 +Developmental glaucoma 0.4835918480485984 2.515990764340357 0.011869829320988 1.0 0.2153633321256008 31 P61254,P62273,P62913,P62081,P62857,P46777,P62899,P39019,P21333 9 +Astrocytoma 0.7394159623907091 2.514783176954374 0.0119105608685774 1.0 0.2153633321256008 9 O75874,P20585,P48735 3 +Abnormality of dental eruption 0.4093086889754073 2.4831922442504264 0.0130210794269711 1.0 0.231835080831935 58 Q9UBM7,Q96GM5,Q8NC56,O60885,P51608,Q92785,Q12824,Q9P2D1,O75147,P36776,Q969G3,Q5JRA6,P61011,O14497,Q9UQE7,Q13045,Q7Z2Z2,P02545,O75369,Q9H2P0,Q6ZRS2,Q96L73,Q5F1R6,O14802,Q8TAQ2,P51610,Q96JJ3,Q15436,Q68CP9,Q9BZI7,P21333,Q14683 32 +Partial duplication of the phalanx of hand 0.5658387314639067 2.4630110407446706 0.0137775673207585 1.0 0.2396550543522845 20 P61254,P62273,P62913,P62081,P62857,P62899,P39019 7 +Nasogastric tube feeding 0.4827688303629609 2.459025983912125 0.0139314534313206 1.0 0.2397757929457295 29 Q6ZRS2,Q9Y448,Q71SY5,P55011,P15311,Q6PJT7,Q6P1N0,Q12904,Q9GZY8,Q15233 10 +Triphalangeal thumb 0.5208467231366227 2.4360303792829523 0.0148494373475498 1.0 0.2431504530871636 24 P61254,P62273,P62913,P62081,P62857,P62899,P39019 7 +Duplication of hand bones 0.3917130048781947 2.4358287025434437 0.0148577186346869 1.0 0.2431504530871636 66 Q9P2D1,P39019,P61254,P62913,P62273,P98175,O60826,P62081,O75369,P62857,P46777,Q13049,P62899,P21333,Q8NCM8,O15078 16 +Nevus 0.4662273831921033 2.4357588004021635 0.0148605899187279 1.0 0.2431504530871636 34 P10412,Q9UQE7,Q01082,O43709,Q99496,Q96AY3,Q8NFV4,Q15056,Q15437,Q9NW13,Q9NYB0,P11802,Q9UIG0 13 +Duplication of thumb phalanx 0.5317862195115658 2.4349664789766545 0.0148931693234817 1.0 0.2431504530871636 23 P61254,P62273,P62913,P62081,P62857,P62899,P39019 7 +Gonadal neoplasm 0.4704697533858729 2.417661834017744 0.0156205861519929 1.0 0.2450948639779465 32 O60934,P20585,O75874,Q92878,P48735,Q96L73 6 +Pierre robin sequence 0.7438073401490388 2.4173216739187877 0.01563519302054 1.0 0.2450948639779465 8 P98175,O75179,Q96DF8 3 +Ovarian neoplasm 0.4930574361297234 2.3987542440675127 0.0164509515660506 1.0 0.2450948639779465 26 O60934,P20585,O75874,Q92878,P48735,Q01844 6 +Delayed eruption of teeth 0.4143297354966248 2.390084127559834 0.0168445138594728 1.0 0.2461523770596548 49 Q96GM5,Q8NC56,O60885,P51608,Q92785,Q12824,Q9P2D1,O75147,P36776,Q969G3,Q5JRA6,P61011,O14497,Q9UQE7,Q13045,Q7Z2Z2,P02545,Q96L73,Q5F1R6,O14802,Q8TAQ2,P51610,Q96JJ3,Q15436,Q68CP9,Q9BZI7,P21333,Q14683 28 +Low anterior hairline 0.4032034279126574 2.3877373920040155 0.0169524503425597 1.0 0.2461813648183601 57 O60885,P62913,Q96N67,Q92785,O15160,O60934,Q969G3,Q04721,Q9NR45,Q9UQE7,P61254,P62273,P62081,P62899,P46777,P62857,P39019,P61353,Q13428,P62847,Q14683 21 +Abnormal female reproductive system physiology 0.3791535283044991 2.383383640922399 0.0171543066174009 1.0 0.2469654677950309 70 P54098,Q9H7N4,O15078,P40818,Q9P2D1,O60934,Q12830,P06748,Q9UQE7,P49257,Q99496,Q14980,P02545,P54132,P35579,P29401,Q15051,O75298,Q6UN15,Q14683 20 +Cone shaped epiphysis 0.5889603253314732 2.3816400030848723 0.017235737685298 1.0 0.2469654677950309 16 Q9Y448,Q15051,Q9Y366,O15078,Q8NCM8,Q6ZRS2 6 +Aplasia hypoplasia involving forearm bones 0.5348816539211759 2.375800817032391 0.017510912493575 1.0 0.2488627392525987 22 Q9P2D1,P61254,Q96AY3,P98175,O75369,Q8NCM8 6 +Thrombocytosis 0.4714341728964114 2.3755795291312145 0.017521416127985 1.0 0.2488627392525987 30 P24752,P62263,P11274,P61254,P62273,P62913,P62081,P62857,P46777,P62899,P39019,P61353 12 +Abnormal number of erythroid precursors 0.5021586759607866 2.3746515956440635 0.0175655215138481 1.0 0.2488627392525987 25 P61254,P62273,P62913,P62081,P62857,P46777,P62899,P39019,P61353 9 +Aplasia hypoplasia of the fibula 0.7833402655219827 2.356430741392861 0.0184515080598646 1.0 0.2579170633177376 7 Q8NCM8,O75369,Q9NWH9 3 +Abnormality of the parathyroid morphology 0.9030294908831258 2.3523977154507074 0.0186528190192563 1.0 0.2579170633177376 5 Q9P2D1,P48735 2 +Myelodysplasia 0.4134477189410395 2.3356064412498263 0.0195117625750211 1.0 0.2624190011375761 48 O60832,P62913,P61011,O00165,P42771,P61254,Q92925,Q7Z2Z2,P62273,Q9UJV9,P62081,P62857,P46777,P54132,P39019,P62899,P38646,P61353,Q5F1R6,P62263,Q01130,P22314,P62847 23 +Short long bone 0.4323743412861108 2.334007916846801 0.0195953073799739 1.0 0.2624190011375761 42 Q9P2D1,Q9Y448,Q15910,Q9NWH9,P61254,O14802,Q9Y366,P98175,O75369,P39019,Q8NCM8,P26373 12 +Scapular winging 0.4952688351722482 2.3150756333894544 0.0206087932671479 1.0 0.2693548708394619 25 O75147,Q8TD16,Q14331,Q9UHD8,P11047,P54098,P02545,O75369,P55072,P21333 10 +Aplasia hypoplasia of fingers 0.3663396722049473 2.31459895651558 0.0206348900406387 1.0 0.2693548708394619 98 Q96ST3,P51608,P18583,P62913,Q92785,Q03252,Q6UX04,Q9P2D1,Q9Y448,Q9UQE7,P61254,P62273,O60826,P62081,O75369,P62899,P62857,P02545,P39019,P46777,Q6ZRS2,Q96T60,P42345,P51610,Q9Y366,Q9BZI7,P21333,Q14683 28 +Pulmonic stenosis 0.4527096606221167 2.3014070773891744 0.0213686322545862 1.0 0.2710119480102839 34 Q9P2D1,O95169,Q9UQE7,O14802,O43709,Q12830,Q8NFV4,Q04721,Q15056,O60826,Q9BU61,Q9UIG0 12 +Early onset of sexual maturation 0.4205548080130012 2.3007926561115717 0.021403353759366 1.0 0.2710119480102839 45 Q6ZRS2,Q9UBM7,O75175,O43709,P55011,Q12830,Q8NFV4,Q15056,Q9BPU6,P02545,Q7Z6Z7,Q8N3R9,O75874,P48735,Q9UIG0,Q96T60 16 +Abnormal tracheal morphology 0.4415859511337893 2.2887116561256917 0.0220961113274511 1.0 0.2782672881806653 37 P06748,Q9P2D1,Q9UBM7,Q13428,O43709,O60832,P55011,Q9NPE3,Q8NFV4,Q15056,Q9Y2W2,Q14807,O75369,P46777,Q9UIG0 15 +Abnormality of the diencephalon 0.4329012683462022 2.283387837158964 0.022407533074001 1.0 0.2787347790474391 40 P54098,Q12824,Q9UIG0,Q9P2D1,O43709,Q969G3,Q8NFV4,P19022,Q96KP1,Q9BU61,O00443,O95169,P78347,Q99496,Q15056,Q92917,Q9GZY8,P49792,P11166,Q9H269,Q14683 21 +Obsessive compulsive behavior 0.4276495691836159 2.2820605949937542 0.022485763022042 1.0 0.2787347790474391 42 Q96ST3,Q9UQN3,O60885,Q92785,Q9UIG0,Q7Z3K3,Q9P2D1,O43709,Q8NFV4,Q8WXI9,P11274,Q9UQE7,Q15056,Q01082,Q9H2P0,Q6ZRS2,P29401,P55072,Q14683 19 +Malignant neoplasm of the central nervous system 0.4796076260005688 2.2787396673174714 0.0226825452433814 1.0 0.2787347790474391 26 O75874,P20585,P48735,Q96L73 4 +Somatic mutation 0.4209919355014817 2.271081797419378 0.0231420266938442 1.0 0.2787347790474391 44 Q92733,Q9Y6D9,Q9NWH9,O60934,Q14980,P20585,O75874 7 +Metrorrhagia 0.7619701706618112 2.253162886409286 0.0242488805416507 1.0 0.2881957746216139 7 Q14980,Q6UN15,P40818 3 +Abnormality of malar bones 0.3798213024948082 2.2451182727016032 0.0247605408578244 1.0 0.2927792197616032 65 P36543,P51608,Q15233,Q7Z3K3,O75147,O75175,Q9P2D1,O60934,P50454,P25490,P11274,P02545,Q14807,O75369,P54132,Q15042,Q13428,O14802,P17980,O60828,P21333,P35573 22 +Neoplasm by histology 0.3718411926207823 2.2211088472487406 0.0263435899543416 1.0 0.303016491380756 110 Q96GM5,P31040,O60885,O60832,P54277,Q05655,P62913,Q15437,P20585,Q92785,Q12824,Q8IY37,P11802,P48735,O60934,Q92804,Q969G3,Q6P1J9,Q15555,Q8WX93,Q9BZE9,Q15477,Q92878,O14497,Q9NYB0,P25490,P26367,P42771,Q01844,P51809,P61254,Q99496,P62273,P02545,P62081,P62899,P54132,Q01082,O75874,P62857,P39019,P46777,P61353,Q96L73,Q8TAQ2,Q96JJ3,Q9H269,P21333,P36957,P62847 50 +Downturned corners of mouth 0.4160735357473217 2.2154371227425407 0.0267300756590114 1.0 0.3062184300192089 44 Q7Z3K3,Q96GM5,O75175,Q9UQE7,O14802,O60885,Q04721,P18583,Q8N201,Q9UNW9,P67870,Q8IY37,O75845,Q6ZRS2,Q14683 15 +Esophageal atresia 0.704822417771862 2.2150919864925176 0.0267537513638473 1.0 0.3062184300192089 8 Q9P2D1,Q8NCM8,P25490,Q9Y2W2 4 +Intestinal atresia 0.6472398156828006 2.2116133388061505 0.0269933929724972 1.0 0.306827837210254 11 Q9P2D1,P18583,O14974,Q9Y2W2,Q7LBC6 5 +Abnormal hemoglobin 0.4707526789671907 2.1990589528885476 0.0278737307045946 1.0 0.3143913266608041 26 Q5F1R6,P61254,P62273,P62913,P62081,P62857,P62899,P39019 8 +Neoplasm of the endocrine system 0.4108665940769728 2.1898282143209253 0.0285366977046366 1.0 0.3195422511649311 45 Q96GM5,P31040,P54277,Q15437,P20585,Q92785,Q12824,P48735,P40818,Q9UER7,Q969G3,Q6P1J9,Q14697,O14497,P25490,Q99496,P02545,O75874,Q8TAQ2,P36957,Q05655 21 +Gynecomastia 0.5204113197375557 2.186073359745732 0.028810238667654 1.0 0.3196572194717151 21 Q9P2D1,O14802,P51608,Q15437,Q9H7N4 5 +Papillary thyroid carcinoma 0.6562211476288096 2.185648172631898 0.0288413553588964 1.0 0.3196572194717151 10 Q96GM5,Q8TAQ2,Q969G3,Q15437,Q92785,Q12824,O14497 7 +Oligodactyly 0.6981285285253819 2.1799415331500933 0.0292617957314036 1.0 0.3196572194717151 8 O60885,Q9P2D1,Q9UQE7,Q14683 4 +Abnormality of the ulna 0.4255201811636552 2.179302719895226 0.0293091873111139 1.0 0.3196572194717151 39 Q9P2D1,O75147,Q9UQE7,P61254,O60885,Q8NFV4,Q15056,O75369,P21333,Q8NCM8,Q9UIG0,Q14683 12 +Aplasia hypoplasia of the radius 0.5447404494450951 2.177818546294138 0.0294195485719344 1.0 0.3196572194717151 18 Q9P2D1,P61254,Q96AY3,P98175,O75369,P39019 6 +Abnormal astrocyte morphology 0.5512916837791256 2.1698537859220597 0.0300179242572724 1.0 0.3236503341613576 17 Q9UQN3,P42345,P54098,P20585,O75874,P48735,Q96L73 7 +Hematological neoplasm 0.3446891042284588 2.1642658443662843 0.0304439524807775 1.0 0.3267275916355044 86 O60885,O60832,P62913,Q9P2D1,O60934,Q8TDP1,P35658,P06748,P11274,P61254,Q9NPE3,Q14980,P62273,P62081,P62899,P54132,P62857,P39019,P33991,P46777,P61353,Q96L73,Q5F1R6,P62263,Q01130 25 +Prominent eyelashes 0.6737109174881805 2.161728900292334 0.0306390786425234 1.0 0.3273098814984058 9 Q96GM5,Q8TAQ2,Q969G3,P20700,Q92785,Q12824,O14497 7 +Macrocytic anemia 0.4287526369254434 2.1546963970391486 0.0311855999356294 1.0 0.3283420047075106 37 Q5F1R6,P61254,P00374,P62273,P62913,P62081,P62857,P62899,P39019 9 +Enchondroma 0.6504521536037433 2.1528364342744575 0.0313315356238133 1.0 0.3286628578868181 10 O75874,P48735 2 +Broad long bones 0.4180521125735435 2.148241866787429 0.0316945463636639 1.0 0.3294956531363456 41 Q9Y448,O75175,Q15910,P55011,Q12830,Q8WXI9,Q9BPU6,Q7Z6Z7,O75369,P21333,Q9H2P0,Q8N3R9,Q96T60,Q96L73 14 +Hand muscle weakness 0.6476540227382064 2.1368843394907855 0.0326074000584428 1.0 0.3359791309791219 10 Q8TD16,Q14315,Q14203,P11047 4 +Abnormality of the incisor 0.4451838166407839 2.124115278490765 0.033660505231605 1.0 0.3415291873608483 30 P55011,Q99496,Q12830,Q8WXI9,Q9BPU6,Q7Z6Z7,Q96N67,Q9BSJ2,P54132,Q8N3R9,Q14683 11 +Limb undergrowth 0.3836799760529568 2.1222588084637595 0.0338160105089422 1.0 0.3423594789434739 56 Q9P2D1,Q9UQE7,P61254,P42345,Q12830,Q9Y366,Q8NCM8,P50454,P98175,O75369,P39019,P21333,O75874,P48735,Q14683 15 +Cleft lip 0.3798926311141697 2.118897338904483 0.034099143900991 1.0 0.344475481973707 59 Q9P2D1,Q13428,P61254,O60934,Q8N201,P62913,P62273,O75179,P62081,O75369,P62899,P62857,P39019,Q8NCM8,Q14683 15 +Down sloping shoulders 0.4502432697307348 2.116322971161937 0.0343173483518424 1.0 0.3459278043188974 27 Q9P2D1,O75175,P55011,Q12830,Q8NFV4,Q15056,Q9BPU6,P02545,Q7Z6Z7,Q8N3R9,Q9UIG0 11 +Neoplasm of the breast 0.433781224081156 2.1109047267169236 0.0347805017331386 1.0 0.3498376440560501 34 O60934,Q99496,P02545,Q15437,P54132,O75874,Q9NYB0,Q92878,P48735 9 +Aplasia hypoplasia of the earlobes 0.6273699851216731 2.0951149985792843 0.0361607709587099 1.0 0.359048388844247 11 Q9P2D1,P98175,O14802 3 +Axial muscle weakness 0.775082639739368 2.086988849262451 0.0368891425195767 1.0 0.3619791491012105 6 Q9Y281,Q8TD16,P11047 3 +Central hypoventilation 0.6792477278078204 2.080136910448366 0.0375129769367699 1.0 0.3654566117928088 8 Q8N183,Q14203,P51608,Q9BU61 4 +Severely reduced visual acuity 0.900744718334756 2.0749430047281416 0.0379918173989137 1.0 0.3656659790838474 4 O15078 1 +Duodenal atresia 0.7229478855339808 2.061746128322061 0.0392319123834661 1.0 0.3758983440123033 7 Q9P2D1,Q9Y2W2 2 +Exostoses 0.769173846537518 2.05964163699305 0.0394328126654501 1.0 0.3762716231136488 6 P48735 1 +Abnormality of the frontal hairline 0.3326054231231435 2.0557743230151417 0.0398042741115616 1.0 0.3784305074314304 81 Q96ST3,Q96GM5,O60885,P62913,O75179,Q96N67,Q92785,O15160,O15344,Q6UX04,O60934,Q92643,Q969G3,Q04721,Q9NR45,Q9UQE7,P61254,P62273,P62081,P62899,P62857,P46777,P39019,Q9H2P0,P61353,Q96L73,Q13428,P62847,Q14683 29 +Tracheoesophageal fistula 0.4938400391623609 2.046053112371234 0.0407511454057303 1.0 0.3836071531730855 22 P06748,Q9P2D1,Q13428,O43709,O60832,P55011,Q9NPE3,Q8NFV4,Q15056,Q9Y2W2,Q9UIG0 11 +Oral cavity bleeding 0.7197229003176747 2.0457658513444894 0.0407794133134289 1.0 0.3836071531730855 7 P06748,Q14980,Q6UN15 3 +Hypoplastic fifth fingernail 0.6717409025640689 2.0401897905946083 0.0413314262146538 1.0 0.3872321322973714 8 Q96GM5,Q8TAQ2,Q969G3,Q92785,Q12824,O14497 6 +Omphalocele 0.5646878346685184 2.03015303211703 0.0423409863228521 1.0 0.39430573836131 14 Q9P2D1,Q8NCM8,O75369,O14974 4 +Restrictive behavior 0.8273103448275716 2.0291457088848865 0.0424434514299552 1.0 0.3944694375900036 5 P51608,Q14683,Q9UQN3,Q01082 4 +Abnormal vena cava morphology 0.6149770845950437 2.021812499831061 0.043195725937795 1.0 0.3986877973062575 11 P47985,Q71SY5,Q99496,P98175,Q7LBC6,Q6ZRS2,Q6UX04 7 +Abnormal nasal base 0.6012278187663308 2.019207745082893 0.0434656316663319 1.0 0.3998269928961627 12 Q96ST3,Q96GM5,Q8TAQ2,Q969G3,Q92785,Q12824,O14497 7 +Abnormal tracheobronchial morphology 0.3695772088931394 2.0171898330091085 0.0436757066688289 1.0 0.3998269928961627 61 P06748,Q9P2D1,Q13432,Q9UBM7,Q92888,Q13428,O60934,O60832,P55011,O43709,Q9NPE3,Q8NFV4,Q15056,Q9Y2W2,O75369,P46777,P54132,Q9UIG0 18 +Neck flexor weakness 0.7570698733803629 2.0033992310099946 0.0451344539482359 1.0 0.4053543899391734 6 Q13049 1 +Increased nuchal translucency 0.5281127126882827 2.0032570133444967 0.0451497089221311 1.0 0.4053543899391734 17 Q9UBM7,Q9UQE7,O60885,Q8NFV4,Q15056,Q9UIG0,Q14683 7 +Bone marrow hypercellularity 0.6103789998009151 1.9944935230476468 0.0460981470959445 1.0 0.4116144472996125 11 P06748,Q14980,Q01130,Q6UN15 4 +Neoplasm of the colon 0.4062907179593424 1.994034402325265 0.0461482950383254 1.0 0.4116144472996125 40 P61254,P62273,P62913,P62081,P20585,P62857,P62899,P39019 8 +Abnormal duodenum morphology 0.532679604748996 1.9895473832806516 0.046640817223958 1.0 0.4152104935627072 16 Q9P2D1,P98175,Q7LBC6,Q9Y2W2 4 +Pulmonary hemorrhage 0.7066114776382034 1.9805520515075683 0.0476415305998378 1.0 0.4200952423101455 7 Q14980,Q6UN15 2 +Abnormality of the hairline 0.3475188508028033 1.9786081369382809 0.0478601428187523 1.0 0.4204273793549005 100 Q96ST3,O60885,P62913,O75179,Q96N67,Q92785,Q7Z6Z7,O15160,O15344,Q6UX04,Q9Y448,O75175,O60934,Q969G3,Q04721,P19022,Q9UQE7,P61254,P62273,O60826,P62081,P62899,P62857,P46777,P39019,Q15042,P61353,Q9H2P0,Q6ZRS2,Q96L73,Q13428,Q9Y2W2,Q14683 33 +Broad finger 0.4024316133375583 1.975625876328404 0.0481971656856126 1.0 0.4225891112095128 41 Q9Y448,O75175,Q15910,P55011,Q12830,Q8WXI9,Q9BPU6,Q7Z6Z7,O75369,P21333,Q9H2P0,Q8N3R9,Q96T60,Q96L73 14 +Abnormality of the radial head 0.6188039274692556 1.9710182725988792 0.048721785797904 1.0 0.423989023600862 10 P21333,Q04721,Q6ZRS2 3 +Embryonal neoplasm 0.4451365900298011 1.965741449401468 0.0493284842431145 1.0 0.4271982078663934 26 Q96GM5,Q13263,Q8TAQ2,Q969G3,Q6P1J9,P20585,Q92785,P54132,Q8IY37,Q12824,Q15477,O14497,P26367,Q96L73,P51809 15 +Urethral obstruction 0.5000893654083984 1.9609627670767824 0.0498833663861755 1.0 0.4279927957337575 20 P06748,O60832,Q9NPE3,Q8NFV4,Q15056,P21333,Q15149,Q9UIG0,Q6ZRS2,Q96L73 10 +Abnormally low pitched voice 0.637306451867163 1.9606601749846164 0.0499186777033993 1.0 0.4279927957337575 9 Q15910,Q9UQE7,Q96L73,Q14683 4 +Hepatoblastoma 0.6161883392516985 1.955858585872031 0.0504818151198165 1.0 0.4296501737395374 10 Q96GM5,Q8TAQ2,Q969G3,Q92785,Q12824,Q15477,O14497 7 +Abnormal patella morphology 0.4252328915479486 1.9503176059305671 0.0511382754998179 1.0 0.431153968652587 31 P46821,O43709,Q04721,Q96AY3,Q8NFV4,Q15056,Q14807,O75369,P21333,Q6ZXV5,Q9UIG0,P25490 12 +Impaired use of nonverbal behaviors 0.9619625137816972 1.943520290604121 0.0519533262098095 1.0 0.4365770468299907 2 Q9GZY8 1 +Abnormality of the endometrium 0.6134129602334851 1.93975132540178 0.052409918679579 1.0 0.4385434805195686 10 P20585 1 +Multiple enchondromatosis 0.7428192402441554 1.936806856731255 0.0527689574535616 1.0 0.438722455606534 6 O75874,P48735 2 +Micromelia 0.4619106607474845 1.934811572431085 0.0530134224832887 1.0 0.438722455606534 24 Q9UBM7,Q9UQE7,O60885,P50454,O75369,O75874,Q8NCM8,P48735,Q14683 9 +Neoplasm of the parathyroid gland 0.8661677672668877 1.9336779924180512 0.0531527313334363 1.0 0.438722455606534 4 P48735 1 +Parathyroid adenoma 0.8661677672668877 1.9336779924180512 0.0531527313334363 1.0 0.438722455606534 4 P48735 1 +Syndactyly 0.3407708046163037 1.932525178110464 0.0532947174646329 1.0 0.4391144540038111 96 Q96ST3,Q9UBM7,O60885,P55011,P51608,Q13049,Q9NQ48,O15078,O14974,P98175,Q15910,P11274,Q9UQE7,O60826,P02545,O75369,P54132,Q9H2P0,Q15149,Q96L73,P11166,O14802,P51610,Q9Y366,Q9BZI7,Q14692,P82673,P21333,Q8NCM8,Q14683 30 +Hypoplastic fifth toenail 0.6304699096525896 1.9224925749379649 0.0545438069913088 1.0 0.4415708098641627 9 Q96GM5,Q8TAQ2,Q969G3,Q92785,Q12824,O14497 6 +Cafe au lait spot 0.3818312046138667 1.9195432335570048 0.0549156203081762 1.0 0.4415708098641627 47 Q96ST3,O60934,P42345,P55011,Q12830,Q9BPU6,Q9NP58,Q9Y2W2,Q7Z6Z7,Q15437,P54132,Q8N3R9,Q6UX04 13 +Aggressive behavior 0.3284069125993767 1.916083541926756 0.0553544628296593 1.0 0.4415708098641627 78 Q96ST3,P23378,Q9UBM7,Q9UQN3,P51608,P53597,Q92785,Q15233,P17480,Q12830,Q13409,Q9BPU6,Q9UGM6,Q7LBC6,Q01082,Q9H2P0,Q6ZRS2,Q96L73,P11166,Q96DF8,P55072 21 +Abnormal renal medulla morphology 0.5840878888576491 1.9138904648436996 0.0556341530032642 1.0 0.4415708098641627 12 Q15051,O15078 2 +Gangrene 0.5836996322661046 1.9114942399839716 0.0559410963120718 1.0 0.4421059091193844 12 Q14980,Q8NBM4,Q6UN15 3 +Broad forehead 0.3918376204425932 1.9092978814175945 0.0562236754643645 1.0 0.4434138327949424 43 O75147,Q15910,O14802,O43709,Q8NFV4,Q8WXI9,Q15056,Q9Y2W2,P19022,O60826,Q01082,P21333,Q9UIG0,Q96L73,P25490 15 +Chondrosarcoma 0.8601035518917135 1.908726127146767 0.0562974308906856 1.0 0.4434138327949424 4 P48735 1 +Aplasia hypoplasia of the ulna 0.5647879428057645 1.9059886283607208 0.05665168104653 1.0 0.4440257186050234 13 Q9P2D1,Q8NCM8,P61254 3 +Breathing dysregulation 0.8588150863279044 1.9034180600445112 0.0569860163006255 1.0 0.4440257186050234 4 O75380 1 +Diffuse alveolar hemorrhage 0.7337183646372356 1.8940725252574369 0.0582153839748869 1.0 0.4478922008796349 6 Q14980,Q6UN15 2 +Addictive behavior 0.7337183646372356 1.8940725252574369 0.0582153839748869 1.0 0.4478922008796349 6 Q14980,Q6UN15 2 +Abnormal oral physiology 0.3613781149637901 1.8891980514624709 0.058865295738854 1.0 0.4507148529603513 60 P06748,Q14203,Q9UQN3,O14802,P55011,P51608,Q14980,P51610,P11047,P09417,P43243,Q9BZI7,P55072,Q01082,Q9H2P0,Q03252,Q6UN15,Q15233 18 +Hyperkalemia 0.7325349624408832 1.88850415127831 0.0589583011411436 1.0 0.4507148529603513 6 Q9NP58 1 +Neoplasm of the adrenal cortex 0.7316090195471527 1.8841453916620832 0.0595453117571924 1.0 0.4507148529603513 6 P48735 1 +Upper extremity joint dislocation 0.4817891597350978 1.8792908192405384 0.0602047945861095 1.0 0.4507148529603513 21 Q9UQE7,O60885,Q04721,Q14807,O75369,P21333,Q6ZXV5,Q6ZRS2,Q14683 9 +Nephronophthisis 0.6863771533522605 1.8791619024757404 0.0602223898497311 1.0 0.4507148529603513 7 Q15051,O15078 2 +Flared nostrils 0.7929408843414402 1.879120118839054 0.0602280936232384 1.0 0.4507148529603513 5 O75179 1 +Abnormality of corneal thickness 0.5109392368199438 1.8783881096713988 0.0603280909277681 1.0 0.4507148529603513 17 Q15051,O15078 2 +Abnormal platelet volume 0.6406780699537048 1.873350886715352 0.0610199472669314 1.0 0.4530241690130325 8 Q15477,Q14739,P21333,P35579,O75845 5 +Neoplasm of the large intestine 0.3749686902222326 1.8732987514659536 0.0610271421997328 1.0 0.4530241690130325 48 P39019,P61254,P62913,P62273,Q13043,Q15437,P20585,P62081,P62857,P46777,P54132,P62899 12 +Abnormality of the pylorus 0.4126753384868057 1.8701490132010936 0.0614631277818045 1.0 0.4555329422680153 33 Q9UBM7,P11274,Q9UQE7,O60885,P51610,P51608,P50454,Q9BZI7,P21333,Q6ZXV5,Q15149,Q14683 12 +Hamartoma 0.4940739046929666 1.8565758337066096 0.0633715247630637 1.0 0.4580914517120787 19 O75874,P20585,P48735 3 +Postaxial polydactyly 0.4195143020755753 1.8556452238985348 0.0635041431412575 1.0 0.4580914517120787 29 Q9Y366,P98175,Q9Y2V7,Q13049,Q8NCM8,O15078 6 +Encephalocele 0.5010729952299084 1.8548055562716663 0.0636239983267321 1.0 0.4580914517120787 18 Q15051,Q13428,O75369,Q6ZXV5,O15078,P07942 6 +Dialeptic seizure 0.3653890936511291 1.8544233917689872 0.0636786108046412 1.0 0.4580914517120787 53 P11166,P42345,P51610,P00374,P51608,Q8TB37,Q8WXI9,Q96JM3,P18583,P19022,Q96T60,Q96L73 12 +Productive cough 0.681368456295107 1.853929366894445 0.0637492658498972 1.0 0.4580914517120787 7 Q14980,Q6UN15 2 +Polymicrogyria 0.3223805931154101 1.8520751205063015 0.0640150365669609 1.0 0.4580914517120787 83 P46821,Q9BVA1,Q8TD16,P55011,P51608,P36543,P18583,Q8IY37,Q6ZXV5,Q9UN37,Q71SY5,P15311,O14974,Q96JM3,Q6PJT7,Q6P1N0,Q96N66,O95721,Q15042,Q12904,O14802,P42345,Q8WXW3,Q16625,P67870 25 +Medial flaring of the eyebrow 0.6794228757691434 1.8441140530469051 0.0651665203063771 1.0 0.4580914517120787 7 Q96ST3,Q13049,O15078 3 +Abnormal forearm bone morphology 0.4602756852981581 1.8415842395071895 0.0655359881380883 1.0 0.4580914517120787 23 Q9P2D1,P61254,P98175,O75369,P39019,Q8NCM8 6 +Absent forearm bone 0.8436445636591885 1.840752110820324 0.0656578935817491 1.0 0.4580914517120787 4 Q9P2D1 1 +Horseshoe kidney 0.3752506938777122 1.840560229420278 0.0656860303881559 1.0 0.4580914517120787 47 Q9P2D1,P61254,P18583,P62913,P62273,P98175,P62081,Q92785,P62857,P62899,P39019,Q6UX04 12 +Limb girdle muscle weakness 0.4185642349503674 1.8302749108283352 0.0672088410682596 1.0 0.4654537771150559 28 Q9Y281,Q8TD16,O75190,P43243,Q14331,P54098,P02545,Q14315,Q13049,Q15149 10 +Tetralogy of fallot 0.370694433549077 1.821237360207864 0.068570783642158 1.0 0.4720717504964571 48 Q96GM5,P62913,Q14839,Q92785,Q12824,Q9UIG0,O00192,Q9P2D1,O43709,Q969G3,Q04721,Q8NFV4,P98175,Q15477,O14497,Q15056,O60826,P46777,Q6ZRS2,Q8TAQ2,Q96DF8,O60828 22 +Retinal coloboma 0.5504684784407613 1.8137565244397384 0.0697152185328202 1.0 0.4772795812032479 13 Q9P2D1,Q8N201,O15078 3 +Chronic leukemia 0.7166709313364197 1.813608147231968 0.0697380752392953 1.0 0.4772795812032479 6 Q8TDP1,Q01130 2 +Coloboma 0.3584502142586931 1.8066271767923612 0.0708204291685064 1.0 0.4825550356980193 57 Q96ST3,Q7Z3K3,Q9P2D1,Q9UBM7,Q13428,Q9Y467,Q8N201,Q9NP58,O15347,O60826,Q9H2P0,Q01082,O60828,P21333,Q15042,O15078 16 +Misalignment of incisors 0.714448491940046 1.803079547246234 0.0713757227380025 1.0 0.4842087351291938 6 Q99496,Q9BSJ2,Q8WXI9 3 +Hip dysplasia 0.3598369405693717 1.792087972965344 0.0731188751360565 1.0 0.4931544452209792 54 Q9UQE7,O14802,Q8TD16,O60885,P55011,P36543,Q12830,Q9BPU6,P02545,Q7Z6Z7,Q9Y2V7,Q7LBC6,Q8N3R9,Q6ZRS2,Q14683 15 +Abnormal hair pattern 0.3610134726445106 1.7886685565964435 0.0736682097315615 1.0 0.494705448876541 129 Q96ST3,O60885,P55011,P62913,O75179,Q96N67,Q92785,Q7Z6Z7,O15160,O15344,Q6UX04,Q9Y448,O75175,O60934,Q969G3,Q04721,Q12830,P98175,P19022,P25490,Q9UQE7,P61254,Q9BPU6,P62273,O60826,P62081,P02545,P62899,P54132,P62857,P39019,P46777,Q15042,P61353,Q9H2P0,Q6ZRS2,Q96L73,Q13428,P11166,Q9Y2W2,O60828,P21333,Q8N3R9,Q14683 44 +Premature ovarian insufficiency 0.4448722537269334 1.7864093812334043 0.0740329977719296 1.0 0.4949125766842753 24 Q15051,O60934,P02545,P54098,P82650,P54132,O15078,Q15031,Q05655,P40818 10 +Phthisis bulbi 0.7714879681145506 1.784527052726755 0.0743380629493488 1.0 0.4949125766842753 5 Q9UQE7,Q14683 2 +Papillary renal cell carcinoma 0.7703332351619335 1.7794161205137595 0.0751715654838998 1.0 0.4971026686887496 5 Q92733,Q9NWH9 2 +Abnormality of the hypothalamus pituitary axis 0.3293816402270718 1.7786494247800817 0.075297255655516 1.0 0.4971026686887496 74 Q96ST3,P54277,Q8IY37,Q12824,P48735,O15078,P40818,Q15233,Q9P2D1,Q969G3,Q14697,Q9NW13,P61011,P25490,P51809,Q96IJ6,Q99496,Q7LG56,Q7Z2Z2,O75369,P33991,O75874,Q9H2P0,Q5F1R6,P51659,O14802,Q8WXW3,P82650,Q15031,Q06787,Q14683 31 +Mixed hearing impairment 0.6047801561153441 1.778001748782024 0.0754035676704139 1.0 0.4971026686887496 9 Q9P2D1,O75369,P62857 3 +Polygenic inheritance 0.7692244941320668 1.7745069587140303 0.0759793320800314 1.0 0.4989772189767528 5 O60934,P35658,P50454 3 +Gastrointestinal carcinoma 0.4031989931554755 1.7735811394896437 0.0761324596819856 1.0 0.4989772189767528 33 P61254,P62273,P62913,P62081,P62857,P62899,P39019 7 +Cerebral palsy 0.5441630952061701 1.7729493224805413 0.0762371046854948 1.0 0.4989772189767528 13 P98175,P48735 2 +Joint hypermobility 0.3364930634384046 1.7674438260009442 0.0771539287723279 1.0 0.501947181975817 102 Q96ST3,Q9Y281,P55011,P18583,O75179,Q7Z6Z7,Q6ZXV5,Q03252,Q9UIG0,O75147,O75175,O43709,Q04721,Q8NFV4,Q12830,Q96JM3,P25490,Q15910,Q9BPU6,Q15056,P02545,O75369,Q7LBC6,Q15042,Q7L2E3,Q96L73,Q5F1R6,O14802,Q9Y366,Q9BZI7,P21333,Q8N3R9 32 +Non motor seizure 0.3719004235066728 1.766983735180047 0.0772309522514975 1.0 0.501947181975817 46 P11166,P51610,P00374,P51608,Q8TB37,Q8WXI9,Q96JM3,P18583,Q96T60,Q96L73 10 +Wide intermamillary distance 0.4424346339586458 1.7650733045967162 0.077551446565435 1.0 0.5033262181418665 24 Q9P2D1,Q9Y448,Q9UBM7,O14678,Q96KP1,Q9H2P0 6 +Curly eyelashes 0.7056557936023574 1.7613410167086914 0.078180701719702 1.0 0.5045912790159103 6 Q9UQE7,Q14683 2 +Aplasia hypoplasia of the cerebellar vermis 0.3134992360797327 1.7594570982503048 0.078499901031662 1.0 0.5052479779697141 80 Q9P2D1,Q15051,Q9UBM7,O14802,P36543,Q8N201,Q9BPU6,P98175,Q9UGM6,O60826,Q92785,Q96L73,Q96KP1,Q8NCM8,Q9UN37,O15078,P07942 17 +Fibular hypoplasia 0.7651844139851973 1.756604027402467 0.0789853260386044 1.0 0.5062687035881307 5 Q8NCM8,Q9NWH9 2 +Insomnia 0.5050080646681792 1.7548645499678084 0.0792824791361317 1.0 0.506944297603102 15 Q14203,Q8NFV4,Q15056,P08397,Q9UIG0,P25490 6 +Fatiguable weakness of proximal limb muscles 0.8209617428577427 1.7465037900362892 0.0807234490726127 1.0 0.5136562152322495 4 Q14315 1 +Gowers sign 0.5037209452556326 1.7457791114979997 0.0808493420134919 1.0 0.5136562152322495 15 Q9Y281,Q8TD16,Q13049 3 +Optic disc hypoplasia 0.7014348785871882 1.741258089157185 0.0816383490654142 1.0 0.5136562152322495 6 O14802,O95721,Q96KP1,Q9H3H1,Q00839 5 +Ovarian cyst 0.4858835458805903 1.740679506810313 0.0817397724193829 1.0 0.5136562152322495 18 Q8NFV4,Q15056,P02545,Q15437,P20585,Q03252,Q9UIG0 7 +Broad thumb 0.3991754203747031 1.7324477796909323 0.083193867172199 1.0 0.5136562152322495 33 Q15910,P55011,Q12830,O75369,P21333,Q9H2P0,Q8N3R9,Q96L73 8 +Recurrent fractures 0.3967694854470834 1.7314804367016277 0.0833661111618411 1.0 0.5136562152322495 34 Q9P2D1,Q8N1G0,Q96AY3,O75874,P48735 5 +Holoprosencephaly 0.496231079908508 1.728807842474421 0.0838434920925712 1.0 0.5136562152322495 16 Q9P2D1,O14974,O15078,Q92917,Q14683 5 +Stomatitis 0.4960641068756228 1.7276030424452715 0.0840594169841579 1.0 0.5136562152322495 16 Q14980,Q8NBM4,Q9Y4L1 3 +Abnormal localization of kidney 0.3342220504129247 1.7273922403589834 0.0840972432722895 1.0 0.5136562152322495 70 Q96GM5,Q9UBM7,O60832,P18583,P62913,Q92785,Q12824,Q9UIG0,Q6UX04,Q9P2D1,Q9Y448,O43709,Q969G3,Q8NFV4,Q9Y2U8,P98175,O14497,Q00839,P78347,P61254,Q15056,P62273,P62081,P62857,P46777,P62899,P39019,Q15042,P61353,Q8TAQ2,P62847,O75845 32 +Blepharophimosis 0.3599394028638958 1.7262188917697792 0.0843080405729881 1.0 0.5136562152322495 49 O75175,P11274,O43709,P55011,P51608,Q12830,Q9UHD8,Q8NFV4,Q8WXI9,P38159,Q15056,Q9BPU6,Q7Z6Z7,P02545,Q96DF8,Q8N3R9,Q9UIG0,Q92917 18 +Abnormal shoulder morphology 0.3960169162397785 1.7236890845938857 0.0847639865847393 1.0 0.5136562152322495 34 Q9P2D1,O75175,O43709,P55011,Q12830,Q8NFV4,Q15056,Q9BPU6,P02545,Q7Z6Z7,P21333,Q6ZXV5,Q8N3R9,Q9UIG0 14 +Melanocytic nevus 0.5533322484742614 1.7227362978284568 0.0849362231411752 1.0 0.5136562152322495 12 Q15437,Q96AY3,Q9NW13 3 +Menorrhagia 0.8151112889616562 1.7220945933851646 0.0850523843580011 1.0 0.5136562152322495 4 P49257,P40818 2 +Hamartomatous polyposis 0.8141383036102205 1.718031334961614 0.0857908999334848 1.0 0.5164123212317412 4 P20585 1 +Interrupted aortic arch 0.8128466902039421 1.7126358241461317 0.0867795583756094 1.0 0.5183349714286082 4 Q9P2D1,Q96DF8 2 +Atresia of the external auditory canal 0.4988432380298887 1.7113035514587298 0.0870250910998373 1.0 0.5191342725814432 15 Q13428,Q9UQE7,P61254,P62913,Q14683 5 +Large basal ganglia 0.474682214049238 1.7071843442204844 0.0877877940026774 1.0 0.5223429945332165 19 Q71SY5,P55011,P15311,Q6PJT7,Q6P1N0,Q12904 6 +Pituitary adenoma 0.5330115786384038 1.7005109454547158 0.0890348593519798 1.0 0.526639685251195 13 O75874,P48735 2 +Pelvic girdle muscle weakness 0.572376159388085 1.6991823444587937 0.0892848319397605 1.0 0.526639685251195 10 Q13049,O75190,Q14315,Q15149 4 +Abnormal humerus morphology 0.9038037486218308 1.6989203465311316 0.0893341927852988 1.0 0.526639685251195 2 O75369 1 +Astigmatism 0.3483130702877551 1.698483465269041 0.0894165508205708 1.0 0.526639685251195 59 Q5F1R6,Q7Z3K3,P10412,P55011,Q99496,Q12830,Q8N201,Q92974,Q8WXI9,O14974,Q9BPU6,Q7Z6Z7,Q9HD42,P21333,Q9H2P0,Q8N3R9,Q96L73,P25490 18 +Muscle fiber splitting 0.9004961411245973 1.6849239757541177 0.0920032401502304 1.0 0.5312668832490612 2 Q14315 1 +Aortic aneurysm 0.3472296219378999 1.6839533739674946 0.0921906800336995 1.0 0.5312668832490612 59 P46821,P55011,Q7Z6Z7,Q6ZXV5,Q9UIG0,Q02809,Q9P2D1,O75175,O43709,Q12830,Q8NFV4,Q8TDP1,P11274,Q15056,Q9BPU6,P02545,O75369,Q01082,Q96L73,P21333,Q8N3R9 21 +Ulnar deviation of the hand or of fingers of the hand 0.5303690749584465 1.6832985818558377 0.0923173048183467 1.0 0.5312668832490612 13 Q9UBM7,Q9BPU6,Q9NW13,P21333,Q15042 5 +Neoplasm of the gastrointestinal tract 0.3264375334941151 1.681823824624108 0.0926030074094554 1.0 0.5312668832490612 97 Q96GM5,Q9NWH9,P31040,P54277,Q05655,P62913,Q15437,P20585,Q92785,Q12824,P11802,Q9UER7,O60934,Q969G3,Q13043,P50336,Q8WX93,Q15477,Q92878,O14497,Q9NYB0,P25490,P42771,P61254,Q99496,P62273,P08397,P02545,P62081,P62899,P54132,P62857,P39019,P46777,P61353,Q9UDY2,P42345,Q8TAQ2,P62847 39 +Abnormality of vitamin metabolism 0.4013272214732759 1.6776871401670574 0.0934081912269053 1.0 0.5345663357529916 29 Q5F1R6,P11586,Q01968,Q9UDY2,O14678,P51610,Q7Z2Z2,P30038,P53597,P62913,Q13043,Q4G176,Q01082,Q9Y3A5,P61011,Q05655,P46783 17 +Hoarse voice 0.3993030785549843 1.6739539049013248 0.0941396588699561 1.0 0.5367770505488139 30 Q15910,P43243,Q8NFV4,Q15056,Q7Z406,Q8TDP1,Q01082,P21333,Q9UIG0,Q96L73 10 +Abnormality of neutrophils 0.3199557366657314 1.6739470057325625 0.0941410148907431 1.0 0.5367770505488139 91 Q9Y3C6,Q9NRZ9,P31040,O60832,Q05655,Q14739,P62913,P26038,P18206,Q13043,P61011,O00165,P06748,P54819,P61254,Q92925,Q9NPE3,Q14980,Q7Z2Z2,P62273,P02545,P62081,Q9H078,P62899,P62857,P46777,P39019,P35579,Q14126,P61353,Q5F1R6,P42167,P01889,P18074,P62263,O14678,Q01130,P62847,Q6UN15 39 +Short philtrum 0.3202313259967557 1.671337550470793 0.0946550234043352 1.0 0.5376872989820114 75 P18583,O75179,Q7Z6Z7,Q92785,Q96N67,Q15233,Q7Z3K3,Q12830,Q8WXI9,Q96JM3,P19022,Q99496,Q9BPU6,O60826,Q01082,Q15042,Q6ZRS2,O14802,P17980,Q9BZI7,O60828,Q14683 22 +Abnormality of the pituitary gland 0.335577445698259 1.6702030960074896 0.0948791876835053 1.0 0.5376872989820114 67 Q96ST3,P54277,Q8IY37,Q12824,P48735,P40818,Q15233,Q9P2D1,Q969G3,O14654,Q14697,Q9NW13,P61011,P25490,P51809,Q96IJ6,Q9UBS4,Q99496,Q9Y285,Q7Z2Z2,Q7LG56,O75369,P33991,O75874,Q9H2P0,Q5F1R6,P51659,O14802,P82650,Q15031,Q9Y3A5,Q06787,Q14683 33 +Spondylolysis 0.8960859977949285 1.6662507799762318 0.0956634756621541 1.0 0.5388462683660974 2 O75369 1 +Capitate hamate fusion 0.8960859977949285 1.6662507799762318 0.0956634756621541 1.0 0.5388462683660974 2 O75369 1 +Abnormality of vitamin k metabolism 0.6851545253863169 1.6635297972348615 0.0962064313733428 1.0 0.5403115325123662 6 Q5F1R6,Q9UDY2,Q7Z2Z2,Q13043,P61011 5 +Poor suck 0.401334794635496 1.663199924127 0.0962724228362899 1.0 0.5403115325123662 28 O95169,Q9UBM7,Q14683,P22314,P11047,Q01082,Q9BU61,O60828,Q15233 9 +Tongue thrusting 0.8947078280044203 1.660412852458537 0.0968314263304377 1.0 0.5407717006080471 2 P51608 1 +Hand apraxia 0.8947078280044203 1.660412852458537 0.0968314263304377 1.0 0.5407717006080471 2 P51608 1 +Smooth philtrum 0.3216408198654674 1.6593099201857175 0.0970533573120908 1.0 0.5407717006080471 74 Q96ST3,Q8NC56,P55011,P36543,P18583,P10586,Q7Z6Z7,O75179,O75175,Q12830,P19022,Q9BSJ2,Q96KP1,P11274,Q9UQE7,Q9BPU6,Q01082,Q9H2P0,Q6ZRS2,P42345,P67870,P21333,Q8N3R9,Q14683 24 +Abnormality of the thoracic cavity 0.4906754859442967 1.65342315030714 0.0982447745501775 1.0 0.5433272544123104 15 Q5F1R6,P01889,O60885,Q99496,Q969G3,Q7Z2Z2,Q12824,P61011,Q05655,Q01844 10 +Abnormal morphology of the radius 0.5082248173869961 1.650956822874739 0.0987473916581733 1.0 0.5433272544123104 14 P39019,P98175,O75369,P61254 4 +Oral aversion 0.5640837152119687 1.6500765907649273 0.0989272719595111 1.0 0.5433272544123104 10 P24752,Q96GM5,Q8TAQ2,Q969G3,Q92785,Q12824,O14497 7 +Patellar dislocation 0.4458265150681937 1.6499161529805717 0.0989600864718407 1.0 0.5433272544123104 22 P46821,O43709,Q04721,Q8NFV4,Q15056,O75369,P21333,Q6ZXV5,Q9UIG0 9 +Urethral stenosis 0.479852028228049 1.6496788159226323 0.0990086452069167 1.0 0.5433272544123104 17 P06748,Q9NPE3,O60832,Q8NFV4,Q15056,P21333,Q15149,Q9UIG0 8 +Biconcave vertebral bodies 0.6407275387214164 1.6473901366707808 0.0994778813976806 1.0 0.5442217878305738 7 Q14807,Q04721,Q96AY3,P40818 4 +Preauricular skin tag 0.4668277617532785 1.6463308514024146 0.0996956610251968 1.0 0.5444015708391187 19 Q9P2D1,Q13428,O60826,Q9Y2W2 4 +Blepharitis 0.4842379859325591 1.6420694702145937 0.1005756078339237 1.0 0.546944516961764 16 P06748,Q9UQE7,O60885,Q9NPE3,P78536,Q14683 6 +Lacrimation abnormality 0.4594138689394378 1.640690677225331 0.1008616411398453 1.0 0.546944516961764 20 Q9P2D1,O60832,P55011,Q9NPE3,Q8NFV4,Q15056,Q9UIG0 7 +Synostosis involving bones of the upper limbs 0.3920814280132402 1.6386419037747209 0.1012878599046485 1.0 0.546944516961764 32 Q9UQE7,Q14683,O60885,P61254,Q8NFV4,Q15056,O75369,O60828,P21333,Q9UIG0,Q15233 11 +Abnormality of the parathyroid gland 0.4187754517315253 1.6350676517176537 0.1020348664729235 1.0 0.546944516961764 25 O75874,Q9P2D1,P48735 3 +Neoplasm of the pituitary gland 0.4718839741630479 1.6348441401247864 0.1020817249316914 1.0 0.546944516961764 18 Q99496,P54277,Q969G3,Q14697,O75874,P48735,P40818,P25490 8 +Colorectal polyposis 0.5504894297564974 1.6332351651578818 0.102419546760569 1.0 0.546944516961764 11 P20585 1 +Aplastic anemia 0.5787939341444711 1.6302986668658614 0.1030383892025881 1.0 0.546944516961764 9 Q5F1R6,O60934,Q9NPE3,Q7Z2Z2,P61011 5 +Abnormal ovarian physiology 0.3972882598401109 1.6237886204620284 0.1044209295402021 1.0 0.5507878088232907 28 Q9P2D1,Q15051,O60934,P54098,P02545,O15078,P40818 7 +Upper limb undergrowth 0.4402662578827533 1.603496336037266 0.1088251174087331 1.0 0.5643649775024704 22 Q9P2D1,P61254,Q12830,P98175,Q8NCM8 5 +Toe clinodactyly 0.4060023377790286 1.6025472971692662 0.109034637364394 1.0 0.5643649775024704 26 P55011,P51608,Q12830,P51610,Q9BPU6,Q9BZI7,Q7Z6Z7,P21333,Q8N3R9 9 +Bimanual synkinesia 0.9179839701028836 1.59698394929944 0.110269285100486 1.0 0.5643649775024704 3 Q9P2D1 1 +Abnormal growth hormone level 0.387919939480666 1.5963682820339908 0.1104065932994613 1.0 0.5643649775024704 32 Q96ST3,Q5F1R6,Q9P2D1,O14802,Q99496,O75369,Q9NW13,Q9H2P0,Q14683 9 +Prostate neoplasm 0.5550290258865922 1.596297264563103 0.1104224405402389 1.0 0.5643649775024704 10 Q92878,Q9Y6D9 2 +Capillary malformation 0.48261325236054 1.596123096790346 0.1104613129300364 1.0 0.5643649775024704 15 Q9UQE7,P42345,O43709,Q8NFV4,Q15056,Q9UIG0 6 +Exodeviation 0.4139683514941549 1.5914426307988347 0.1115099966948762 1.0 0.5662322478144083 25 Q9Y467,Q99496,P18583,Q9UGM6,Q9H2P0 5 +Incomprehensible speech 0.8781697905181993 1.590273551616732 0.111773157611521 1.0 0.5662322478144083 2 Q8WXI9 1 +Increased serum serotonin 0.9155879088298706 1.5876921958599517 0.1123559586237892 1.0 0.5667659187294176 3 P51608 1 +Abnormal upper motor neuron morphology 0.5712680134069583 1.5872737781649162 0.1124506514027379 1.0 0.5667659187294176 9 P43243,O14802 2 +Chorioretinal coloboma 0.5427065917840642 1.585656577754437 0.1128172343153217 1.0 0.56799749497649 11 Q9P2D1,O60826,O15078 3 +Abnormal erythrocyte enzyme level 0.4449266672327467 1.5807393879703575 0.1139376384153605 1.0 0.5680989331718674 21 P61254,P62273,P62913,P62081,P62857,P62899,P39019 7 +Deviation of the thumb 0.4698834133115597 1.575751229086655 0.1150831461172974 1.0 0.5725817773095087 17 Q96ST3,Q9UBM7,Q9UQE7,O75369,P21333,Q14683 6 +Broad nasal tip 0.3416609378445047 1.5745818674522436 0.1153529909693003 1.0 0.5726980224725838 56 Q9Y448,P51610,P36543,P51608,Q12830,P10586,Q8WXI9,Q9BZI7,Q9H2P0,Q7Z6Z7,Q96N67,Q92785,Q9Y2V7,O75369,Q7LBC6,Q15042,Q6ZRS2 17 +Trigonocephaly 0.4960328131612836 1.5678952533620325 0.1169055797327711 1.0 0.5782637493568296 14 Q7Z6Z7,Q92785,Q03252,Q9H2P0,P20700,Q02809 6 +Abnormal prostate morphology 0.5394708842411433 1.5658426868413111 0.1173854500852709 1.0 0.5795654401460079 11 Q92878,Q9Y6D9 2 +Aplasia involving bones of the lower limbs 0.8718302094818065 1.5633516812916763 0.1179698985403416 1.0 0.5795654401460079 2 Q8NCM8 1 +Aplasia involving bones of the extremities 0.8718302094818065 1.5633516812916763 0.1179698985403416 1.0 0.5795654401460079 2 Q8NCM8 1 +Aplasia hypoplasia of the phalanges of the thumb 0.5390475511104587 1.5632490487637714 0.1179940274224562 1.0 0.5795654401460079 11 P21333,Q9Y448,Q9UQE7,Q14683 4 +Myofibrillar myopathy 0.6640444942997218 1.562170778139706 0.1182477626578721 1.0 0.5795654401460079 6 Q9Y281,Q14315 2 +Short phalanx of the thumb 0.5492181905137037 1.561704727483343 0.1183575646005081 1.0 0.5795654401460079 10 P21333,Q9Y448,Q9UQE7,Q14683 4 +Renal agenesis 0.3370031873627278 1.5601002958449046 0.1187361816722261 1.0 0.5808074065587734 60 Q9P2D1,Q9Y448,P39019,P61254,P18583,P62913,P62273,Q9Y2W2,O75179,Q9Y2V7,P62081,P62899,P46777,P62857,Q6ZRS2,Q96L73 16 +Generalized hirsutism 0.3858789555609705 1.5570933939705651 0.1194483132348791 1.0 0.5835878366279514 31 Q9UQE7,O60885,Q04721,Q96JJ3,P02545,O15078,Q13049,Q9NQ48,Q15042,Q03252,P40818,Q14683 12 +Abnormality of upper limb metaphysis 0.9075860434006476 1.5566409282313107 0.1195557608069313 1.0 0.5835878366279514 3 Q15910 1 +Widely spaced incisors 0.7199325163361785 1.5546563370386275 0.1200279386826488 1.0 0.5852778919813946 5 Q99496,Q8WXI9 2 +Pseudobulbar paralysis 0.581800604606074 1.5511605104953554 0.1208632230274473 1.0 0.5864376994797315 8 Q14203,O94979,P08397,P20700,Q15233 5 +Exercise induced myalgia 0.5260056514064961 1.5509346876831136 0.1209173365980951 1.0 0.5864376994797315 12 Q14315,Q13049,P43243 3 +Truncal obesity 0.4664815387186286 1.5504729969548996 0.1210280298305794 1.0 0.5864376994797315 17 Q9UQE7,Q12830,Q9H2P0,P40818,Q14683 5 +Metaphyseal chondrodysplasia 0.661470519500747 1.549772802214111 0.1211960571650894 1.0 0.5864376994797315 6 Q5F1R6,P61011,Q7Z2Z2,Q6UX04 4 +Cortical dysplasia 0.3813080883619695 1.5490680873010918 0.1213653534188972 1.0 0.5864376994797315 33 Q96ST3,Q71SY5,P51659,Q9BVA1,Q12904,P42345,P55011,Q96N66,P15311,O95721,Q13620,O00571,Q6PJT7,Q6P1N0,O00139,P23258 16 +Abnormality of the 1st metacarpal 0.5633921032766103 1.5421464128142055 0.1230380185687156 1.0 0.5912695680339418 9 O60828,Q14683,Q9UQE7,Q15233 4 +Fused cervical vertebrae 0.6178693639731636 1.530014316619739 0.1260131852371775 1.0 0.5991767508875709 7 O75369,Q9Y2W2 2 +Inappropriate laughter 0.5779657882773717 1.5299591547978222 0.1260268394761909 1.0 0.5991767508875709 8 P51608,Q8WXI9 2 +Abnormality of periauricular region 0.4237155709411826 1.529095361440701 0.1262408051164369 1.0 0.5991767508875709 23 Q9P2D1,Q13428,O60826,Q9Y2W2 4 +Abnormality of the periorbital region 0.3170609326360566 1.5275959998251034 0.1266128755670195 1.0 0.5991767508875709 72 P51608,Q14331,P38159,O75179,Q96N67,Q9UIG0,Q9Y448,Q9Y5K6,Q8NFV4,Q8WXI9,P98175,Q96KP1,P25490,Q15056,Q9HCK8,Q01082,P51610,P17980,Q9BZI7,P21333 20 +Abnormal hand morphology 0.3409947665147134 1.5268105317761538 0.1268081319647154 1.0 0.5991767508875709 124 Q96ST3,Q8TD16,P51608,P36543,P62913,Q92785,Q03252,Q6UX04,Q9P2D1,Q9Y448,Q15910,Q9UQE7,P61254,P62273,O60826,P62081,O75369,P62899,P62857,P02545,P39019,P46777,Q6ZRS2,Q96L73,Q96T60,O14802,P42345,P51610,Q9Y366,Q9BZI7,P21333,Q14683 32 +Goiter 0.5330648568313312 1.5265632843419 0.1268696427042681 1.0 0.5991767508875709 11 O75874,P48735 2 +Neoplasm of the nervous system 0.3378045370673647 1.5239371241479298 0.1275244185728943 1.0 0.5996404782468748 56 Q9UER7,O60934,Q99496,P25490,P02545,Q15437,P20585,Q01082,O75874,P48735,Q96L73,Q01844 12 +Bilateral polymicrogyria 0.5764063055949492 1.521331538920509 0.1281766594590045 1.0 0.5999135818391438 8 Q96JM3 1 +Thoracic hypoplasia 0.3784941909661212 1.5201126402747276 0.1284826682628761 1.0 0.5999135818391438 33 Q9Y281,Q5F1R6,P42345,Q9Y366,P50454,P02545,O75369,P39019,P21333,Q8NCM8 10 +Delayed ability to walk 0.3144863529175393 1.517909328453554 0.1290372579884433 1.0 0.6008378134992948 73 P55011,P51608,P24928,P18583,Q7Z6Z7,Q92785,Q6ZXV5,Q03252,Q6UX04,Q15233,Q02809,O75175,P25490,Q13409,Q96D71,Q9BPU6,Q7LBC6,Q15042,Q7L2E3,P67870,Q14683 21 +Broad toe 0.3874478759445489 1.5161556418984965 0.1294800014406383 1.0 0.6013295772827014 27 P55011,Q12830,Q9BPU6,O60826,Q7Z6Z7,P21333,Q9H2P0,Q8N3R9,Q14683 9 +Deviation of toes 0.3457645077290585 1.5159536404745269 0.1295310752872787 1.0 0.6013295772827014 48 Q6UX04,O75175,P55011,P51608,Q12830,Q8NFV4,P25490,Q15056,Q9BPU6,P51610,Q9BZI7,Q7Z6Z7,P21333,Q8N3R9,Q9UIG0,Q15233 16 +Prolonged bleeding time 0.6147068851233974 1.5137204258983032 0.1300967621269695 1.0 0.6021510494064017 7 P35579,Q14692 2 +Abnormality of renal excretion 0.614494198627886 1.5126241925709794 0.1303751453954929 1.0 0.6027185200445386 7 P07741,Q9NQ48,O43772,P18583 4 +Abnormal circulating androgen level 0.4876340772370249 1.5105058634104285 0.1309143943765818 1.0 0.6027185200445386 14 Q9P2D1,O14802,Q99496,Q969G3,Q9NW13,Q8IY37,P51809 7 +Premature ventricular contraction 0.6138966400881096 1.509543967490148 0.1311598281939585 1.0 0.6027185200445386 7 O43772 1 +Recurrent herpes 0.7644819268814744 1.50941683920204 0.1311922924549793 1.0 0.6027185200445386 4 P54132 1 +Finger syndactyly 0.3542598551122116 1.5016542685479868 0.1331864201811154 1.0 0.6079304544487598 44 Q15910,Q9Y366,P98175,O60826,Q14692,Q13049,O15078,Q96L73 8 +Male hypogonadism 0.556329414063728 1.5016001616332686 0.1332004015897481 1.0 0.6079304544487598 9 Q9P2D1 1 +Abnormal blood potassium concentration 0.4862599875493355 1.5011055199251686 0.133328271339062 1.0 0.6079304544487598 14 P40818,Q9NP58 2 +Chronic lymphatic leukemia 0.7073061056685332 1.4979171461739091 0.1341547782898828 1.0 0.6092169329319992 5 Q8TDP1 1 +Large beaked nose 0.6115741897012582 1.4975686786209668 0.1342453495421491 1.0 0.6092169329319992 7 Q8TDP1,P18074,O14802 3 +Neonatal hypoglycemia 0.5280650879908362 1.4958630386302931 0.1346893498684478 1.0 0.610040359491888 11 P42345,Q9UGM6,O43772,Q96L73 4 +Abnormality of mouth shape 0.308718747116645 1.491682052645542 0.1357825162643711 1.0 0.6126032554179928 75 Q96ST3,Q96GM5,O60885,P18583,Q8IY37,Q15233,Q7Z3K3,O75175,Q04721,Q9UNW9,Q96JM3,Q9UQE7,P11047,Q6ZRS2,O14802,P42345,Q8N201,Q96DF8,P67870,O75845,Q14683 21 +Hypopigmented macule 0.7599394831133479 1.4902320769043966 0.136163224910786 1.0 0.6137250302234943 4 Q9NP58,Q15233 2 +Stooped posture 0.8541896361631927 1.4883685999185885 0.1366537127290992 1.0 0.6146920836507029 2 P51608 1 +Waddling gait 0.3806163507340546 1.4879691465055975 0.1367590305351296 1.0 0.6146920836507029 30 Q9Y281,Q8TD16,O75190,P11047,P02545,Q14315,Q13049,P25490 8 +Eyelid coloboma 0.5266024516448311 1.4868754521046443 0.1370477087898649 1.0 0.6148561954555284 11 Q9H2P0,Q9P2D1,Q8TDP1,Q13428 4 +Fibular aplasia 0.8888005270702082 1.4836402515808305 0.1379043849069698 1.0 0.6152383242256948 3 O75369 1 +Abnormality of circulating fibrinogen 0.5695507542344929 1.483367450038319 0.137976810620364 1.0 0.6152383242256948 8 Q14980,Q6UN15 2 +Renal duplication 0.568436329992093 1.4771907980751744 0.1396244997347797 1.0 0.6197087395105267 8 Q15149,Q8NFV4,Q15056,Q9UIG0 4 +Stomatocytosis 0.8867889705824639 1.475816587931864 0.1399931364200695 1.0 0.6201109675911621 3 Q9NP58 1 +Symphalangism of middle phalanx of finger 0.850606394707828 1.4731294352396829 0.1407161377798571 1.0 0.6204059698890004 2 O60828 1 +Anterior pituitary dysgenesis 0.850606394707826 1.4731294352396749 0.1407161377798593 1.0 0.6204059698890004 2 Q9NW13 1 +Neoplasm of the peripheral nervous system 0.4554540099678044 1.468394238137808 0.1419971657999026 1.0 0.6225106620082034 17 Q9UER7,P31040,Q99496,Q969G3,P02545,Q01082,Q12824,P36957,P25490 9 +Freckling 0.4814093784235103 1.4679005929538325 0.1421312271122667 1.0 0.6225106620082034 14 P42771,O60934,Q99496,Q9NP58,Q9NYB0,P11802 6 +Abnormal pulmonary valve physiology 0.3601754022887795 1.4650199059964453 0.1429154868668296 1.0 0.6247678903764415 39 Q9P2D1,O95169,Q9UQE7,O14802,O43709,Q12830,Q8NFV4,Q04721,Q15056,O60826,Q9BU61,P61353,Q9UIG0 13 +Distal lower limb amyotrophy 0.480759253654521 1.4634478541365263 0.143344872445311 1.0 0.6248867226500139 14 Q8TD16,P02545,Q14315 3 +Depressed nasal tip 0.699648471408542 1.463443428272549 0.1433460827081805 1.0 0.6248867226500139 5 P21333,Q96KP1 2 +Abnormal esophagus morphology 0.3413818829624718 1.4621568969140035 0.1436982201554668 1.0 0.625834703901082 48 P06748,Q9P2D1,Q13428,O60832,P55011,Q9NPE3,Q8NFV4,P62913,Q15056,Q9Y2W2,Q9Y2V7,P54132,Q8NCM8,Q15149,Q9UIG0,P25490 16 +Lower limb amyotrophy 0.4490550596577957 1.4612788497665674 0.1439389317236243 1.0 0.6258832538888779 18 Q8TD16,O75298,P02545,Q14315 4 +Bilateral ptosis 0.4542857218737871 1.459688716334759 0.1443756444217458 1.0 0.6259789704654097 17 O95169,P11047,Q9UNW9,Q9BU61,Q9H2P0,Q15149,P26367 7 +Oval face 0.6040609365860091 1.4587893702264374 0.144623089176914 1.0 0.6259789704654097 7 Q9Y4L1,Q96KP1 2 +Abnormality of the shoulder girdle musculature 0.3605256121274313 1.453189497162776 0.1461711474605613 1.0 0.6295248584330201 38 O75147,Q8TD16,O75190,P43243,Q14331,Q9UHD8,P11047,P54098,P02545,O75369,P55072,Q13049,P21333 13 +Aplasia hypoplasia of metatarsal bones 0.5200722689542279 1.4467170884867822 0.1479761763896374 1.0 0.634633217503157 11 Q9Y448,Q15910,Q9Y366,O75369 4 +2 3 toe syndactyly 0.3893056900980484 1.446001853504745 0.1481766819433883 1.0 0.634633217503157 26 O14802,P55011,P51608,P51610,Q9BZI7,Q9H2P0,Q96L73 7 +Perisylvian polymicrogyria 0.6955990413612322 1.4451970301870063 0.1484025503540287 1.0 0.635015332868482 5 P42345,Q15042 2 +Small hand 0.3687548045968192 1.4403173544437382 0.1497776336855321 1.0 0.6385473979235483 34 Q96ST3,Q9UQE7,O60885,Q99496,P51608,Q12830,P18583,Q7Z6Z7,Q9H2P0,Q14683 10 +Abnormality of the breast 0.3281253114072164 1.4392660562225446 0.1500751561401869 1.0 0.6392293772533902 115 Q9UBM7,P51608,P10586,Q15437,Q9H7N4,Q92974,P48735,Q15233,Q9P2D1,Q9Y448,O60934,P19022,Q96KP1,Q9NW13,Q92878,P25490,Q15910,Q9UQE7,Q99496,O60826,P02545,P54132,O75874,Q9H2P0,O14802,O14678,Q14683 27 +Chronic neutropenia 0.6382450331125958 1.4375890695546054 0.1505506840888291 1.0 0.6397380999749414 6 Q5F1R6,Q9Y3C6,Q7Z2Z2,Q9Y3A5,P61011 5 +Iris coloboma 0.3561568096715519 1.437558445007972 0.1505593786820058 1.0 0.6397380999749414 40 Q96ST3,Q7Z3K3,Q9P2D1,Q9UBM7,Q13428,Q9Y467,O60826,Q01082,P21333,Q9H2P0,O15078 11 +Large intestinal polyposis 0.5080592825170867 1.4373886490006595 0.1506075922902057 1.0 0.6397380999749414 12 P20585 1 +Hip contracture 0.492134396790747 1.4326637264106084 0.1519539604709452 1.0 0.6436401082332881 13 Q8TD16,Q96AY3 2 +Congenital diaphragmatic hernia 0.4045668599301903 1.431254652468838 0.1523572453317445 1.0 0.6436401082332881 24 Q96ST3,Q9UBM7,Q9UQE7,O60885,P62857,Q7LBC6,P21333,Q14683 8 +Skin tags 0.4260621734073476 1.4266112212291004 0.153691987977576 1.0 0.6465371805454709 21 Q9P2D1,Q13428,O60826,Q9Y2W2 4 +Hypogonadotropic hypogonadism 0.3711361357326881 1.425530917208041 0.1540037895912234 1.0 0.6465371805454709 32 Q9P2D1,O14802,Q99496,Q8NFV4,Q15056,P54098,Q9NW13,Q9H7N4,Q15042,Q9UIG0 10 +Thromboembolism 0.7445375528520088 1.425095543206519 0.1541295847913457 1.0 0.6465371805454709 4 Q14315 1 +Abnormal hypothalamus physiology 0.5589081891231924 1.4243292496433997 0.1543511842039753 1.0 0.6467718241621941 8 Q9P2D1,Q14683 2 +Limb girdle muscle atrophy 0.4903876733725135 1.421162187507234 0.1552696145357381 1.0 0.6497451940114722 13 Q13049,P02545,Q14331,P55072 4 +Hyposmia 0.4538376629752649 1.4207921271181831 0.1553772001366595 1.0 0.6497451940114722 16 O15078 1 +Toe syndactyly 0.3266833375523587 1.4204378993978937 0.1554802357952995 1.0 0.6497451940114722 60 Q96ST3,Q9UBM7,O60885,P55011,P51608,P11274,Q9UQE7,Q9H2P0,Q15149,Q96L73,O14802,P51610,Q9BZI7,Q14692,P82673,P21333,Q8NCM8,O75845,Q14683 19 +Papilloma 0.5152630512423109 1.4171134134306556 0.1564497714758199 1.0 0.6503018136809265 11 P20585 1 +Abnormal circulating monocarboxylic acid cocentration 0.5572436720072736 1.415086139631205 0.1570432415228944 1.0 0.652171531150036 8 Q5F1R6,P61011,Q7Z2Z2,Q9UDY2 4 +Neonatal hypotonia 0.3251229999457911 1.4126976806167195 0.1577446338450863 1.0 0.6530252082905478 61 Q9Y281,P10412,Q9Y448,Q14683,P51608,Q12830,Q8WXI9,P21333,Q9H2P0,Q96L73,Q6UX04 11 +Spotty hypopigmentation 0.8354465270121345 1.408648939548342 0.1589390001012369 1.0 0.6530252082905478 2 Q9NP58 1 +Hypoplasia of the brainstem 0.3694636802262934 1.408496726015552 0.1589840357464327 1.0 0.6530252082905478 32 Q13409,Q96KP1,Q6ZXV5,P07942 4 +Repetitive compulsive behavior 0.8351708930540447 1.4074766603862483 0.1592860933297686 1.0 0.6530252082905478 2 P51608 1 +Suicidal ideation 0.8351708930540236 1.4074766603861584 0.1592860933297952 1.0 0.6530252082905478 2 Q14203 1 +Abnormal right ventricle morphology 0.5231335532015471 1.4058176524476529 0.1597782788522386 1.0 0.6530252082905478 10 P19022,P11047,P21333 3 +Congenital localized absence of skin 0.8337927232635124 1.4016154134935457 0.161030121740842 1.0 0.6536725244200221 2 Q14692 1 +Aplasia cutis congenita over the scalp vertex 0.8337927232635124 1.4016154134935457 0.161030121740842 1.0 0.6536725244200221 2 Q14692 1 +Abnormal dentin morphology 0.6857227353256596 1.4006554874738375 0.1613171195630838 1.0 0.6536725244200221 5 P50454,Q96AY3 2 +Aplasia hypoplasia involving bones of the feet 0.2941308063280578 1.4000186224609608 0.1615077419524695 1.0 0.6536725244200221 79 Q9UBM7,O60885,P55011,P51608,P18583,Q7Z6Z7,Q9NQ48,Q9P2D1,Q9Y448,O75175,Q04721,Q12830,Q15910,Q9UQE7,Q99496,Q9BPU6,P02545,O75369,Q9Y366,P21333,Q8NCM8,Q8N3R9,Q14683 23 +Triangular face 0.3555088166778606 1.3983358574240503 0.1620122349000814 1.0 0.6537284767688262 38 Q96C36,O75147,Q8NC56,O14802,Q14683,P36543,Q12830,Q96AY3,Q04721,P50454,Q7Z6Z7,O75179,O60828,O94979,Q6ZRS2,Q15233 16 +Transient neutropenia 0.684965517241376 1.3972384815395356 0.1623418683432802 1.0 0.6537284767688262 5 Q5F1R6,Q9H078,Q7Z2Z2,P61011 4 +Abnormality of vitamin e metabolism 0.6849655172413756 1.3972384815395342 0.1623418683432806 1.0 0.6537284767688262 5 Q5F1R6,Q13043,P61011,Q7Z2Z2 4 +Aplasia hypoplasia of the optic nerve 0.3838766267848595 1.3950280751662525 0.1630073735303501 1.0 0.6555531489760213 26 Q9Y448,O14802,P18583,Q8WXI9,Q96KP1,Q9H3H1 6 +Bloody diarrhea 0.5529154761269238 1.3910418314213246 0.1642127421754626 1.0 0.6578419076632543 8 Q9UER7,Q15477,Q02241,P78536 4 +Anal stenosis 0.7361661921468324 1.3896478670546704 0.1646358327803458 1.0 0.6589687467099632 4 Q9P2D1 1 +Abnormality of the auditory canal 0.4144971360450876 1.3875976142387976 0.1652596083510633 1.0 0.6597606529273122 22 Q13428,P61254,P55011,P62913,P78536,Q14683 6 +Abnormal aortic morphology 0.3238456112127051 1.3838071574183388 0.1664175108665637 1.0 0.6621080248261316 114 P46821,Q9UBM7,P55011,P53597,P62913,Q7Z6Z7,Q6ZXV5,Q9UIG0,Q02809,Q9P2D1,O75175,O43709,Q12830,Q8NFV4,P19022,Q8TDP1,P11274,P61254,Q9BPU6,Q15056,P62273,P02545,P62081,O75369,P62899,P62857,Q01082,P39019,P46777,P61353,Q6ZRS2,Q96L73,O14678,Q96DF8,P21333,Q8N3R9 36 +Abnormality of the menstrual cycle 0.3262871832491743 1.381675271616296 0.167071430465816 1.0 0.6635734507475618 57 O60885,P54098,Q9H7N4,P40818,Q9P2D1,Q969G3,Q12830,P51809,P06748,Q9UQE7,P49257,Q99496,Q14980,P02545,P35579,P29401,P82650,Q15031,Q6UN15,Q14683 20 +Nasal speech 0.349191264867319 1.3777067383021668 0.1682938500860071 1.0 0.6662678150923615 41 Q13409,P55011,P43243,Q12830,Q9BPU6,Q9BZI7,Q7Z6Z7,Q96DF8,Q8N3R9,O60828,Q15149,Q6ZRS2,Q15233 13 +Volvulus 0.5880513083559217 1.3759970261007823 0.1688225539838606 1.0 0.6662678150923615 7 Q9UQE7,Q14683 2 +Abnormality of skeletal muscle fiber size 0.4058482593399157 1.3752903011326394 0.1690414621915512 1.0 0.6662678150923615 23 Q9Y281,O75190,Q7Z406,P54098,P02545,P55072,Q13049 7 +Aplasia hypoplasia affecting the fundus 0.3718308112389552 1.3750314276462092 0.1691217015719157 1.0 0.6662678150923615 28 Q9Y448,O14802,P18583,Q8WXI9,Q96KP1,Q9H3H1 6 +Expressive aphasia 0.8266262403528335 1.371142395376752 0.1703305711921079 1.0 0.6662678150923615 2 Q9UQN3 1 +Senile plaques 0.8266262403528335 1.371142395376752 0.1703305711921079 1.0 0.6662678150923615 2 Q9UQN3 1 +Lack of insight 0.8266262403528335 1.371142395376752 0.1703305711921079 1.0 0.6662678150923615 2 Q9UQN3 1 +Eeg with continuous slow activity 0.8266262403528335 1.371142395376752 0.1703305711921079 1.0 0.6662678150923615 2 Q9UQN3 1 +Collectionism 0.8266262403528335 1.371142395376752 0.1703305711921079 1.0 0.6662678150923615 2 Q9UQN3 1 +Alexia 0.8266262403528335 1.371142395376752 0.1703305711921079 1.0 0.6662678150923615 2 Q9UQN3 1 +Grammar specific speech disorder 0.8266262403528335 1.371142395376752 0.1703305711921079 1.0 0.6662678150923615 2 Q9UQN3 1 +Nonimmune hydrops fetalis 0.3810601272828896 1.3685840384450088 0.1711293361864334 1.0 0.6682672481162657 26 P61254,P62273,P62913,P62081,P62857,P62899,P39019 7 +Severe muscular hypotonia 0.3613325462101231 1.3630363070530658 0.1728710683758145 1.0 0.6728072485279818 34 Q8TD16,Q9GZY8,O75380 3 +Simplified gyral pattern 0.3628489691575623 1.3590353676702411 0.1741353816643442 1.0 0.673641529074348 33 Q13409,Q96SN8,Q9Y3C6,Q96GM5,Q8TAQ2,Q969G3,P20700,P18583,O14497,Q9UPT5,Q92785,Q13620,Q12824,O94992,Q03252,Q96T60 16 +Macule 0.3138286254392751 1.3576699774426615 0.1745684273661187 1.0 0.673641529074348 67 Q96ST3,O60832,P55011,Q7Z6Z7,Q15437,Q6UX04,Q15233,O60934,Q12830,P06748,Q9NPE3,Q9BPU6,P02545,P54132,Q15149,P42345,Q9NP58,Q9Y2W2,Q8N3R9 19 +Renal dysplasia 0.4450350323064259 1.3565112731986353 0.1749365509989466 1.0 0.673641529074348 16 Q8N201,P18583,Q9BU61,Q8NCM8,Q15149,Q96T60 6 +Overlapping toe 0.403138693541385 1.351955752745617 0.1763894704526056 1.0 0.6740804845339298 23 Q15910,Q9UBM7,Q12830,Q8N201,O60826,Q7Z6Z7 6 +Abnormal cranial nerve physiology 0.2955142982924363 1.3504692082594931 0.1768655241742227 1.0 0.6753443638764282 77 Q9Y281,Q9P2D1,Q14203,O75190,P51608,Q8NBM4,Q14331,P11047,Q99496,P51610,P08397,P02545,Q14692,Q9BZI7,Q13049,O75874,P48735 17 +Weakness of facial musculature 0.3157662677879539 1.3468404047579796 0.17803163855883 1.0 0.6770643160339915 65 Q9Y281,Q9P2D1,Q14203,Q99496,P51608,Q14331,Q9H1B7,P11047,O75190,P51610,Q9BZI7,P54098,Q14692,Q14315,Q13049,Q15149 16 +Gray matter heterotopia 0.3649121360714932 1.345865727824335 0.1783458233928021 1.0 0.6770643160339915 31 P46821,Q96SN8,Q96C36,Q9UBM7,Q9BVA1,O14974,P19022,Q9BSJ2,P21333,Q6ZXV5,Q06787,P23258,P07942 13 +Aortic arch aneurysm 0.5131002547057024 1.3456823924161532 0.1784049672092571 1.0 0.6770643160339915 10 Q9P2D1,Q8NFV4,Q15056,Q9UIG0 4 +Long nose 0.5443241833918532 1.3432822856294162 0.1791805858608648 1.0 0.6770643160339915 8 O60934,Q6ZRS2 2 +Radial bowing 0.7251094319402438 1.3427993959650462 0.1793369390521002 1.0 0.6770643160339915 4 P21333,O75369 2 +Sudden episodic apnea 0.7249566206795028 1.3421517714373077 0.1795467903995709 1.0 0.6770643160339915 4 P51608,O43772 2 +Leukocytosis 0.3782440453712767 1.3421489346742743 0.1795477100041445 1.0 0.6770643160339915 26 P06748,P24752,Q9P2D1,P11274,Q14980,Q01130,Q6UN15,P61011,Q03252,Q9Y4L1 10 +Oligodontia 0.5122738813312369 1.340727371358471 0.180008984373444 1.0 0.6772893373742845 10 P21333,Q6ZRS2,O14802 3 +Abnormal trabecular bone morphology 0.5808015532991175 1.3384561609604766 0.1807477819377405 1.0 0.6772893373742845 7 P06748,Q9NPE3,O60832 3 +Abnormality of thalamus morphology 0.4015595739193608 1.3383584408970874 0.1807796195539746 1.0 0.6772893373742845 23 O95169,P49792,P11166,Q969G3,Q99496,Q9BU61,P54098,Q96KP1,Q12824,O00443,Q9GZY8 11 +Focal emotional seizure 0.5434311003920231 1.3383157772688636 0.1807935208530975 1.0 0.6772893373742845 8 Q96JM3 1 +Multifactorial inheritance 0.4777620529342278 1.3379698680696943 0.1809062594519941 1.0 0.6772893373742845 13 P11274,O60934,P50454,Q8NCM8,P35658 5 +Submucous cleft soft palate 0.8508409153570434 1.3359187178390055 0.181575842208614 1.0 0.6772893373742845 3 P18583,O14802 2 +Primary peritoneal carcinoma 0.5801923346472022 1.3353006161304553 0.1817779770667984 1.0 0.6772893373742845 7 Q92878 1 +Broad eyebrow 0.4764560526986422 1.329361440697237 0.1837287528084561 1.0 0.6772893373742845 13 Q96ST3,Q12830,P18583,O14802 4 +Mask like facies 0.4452046436159943 1.3288326822900256 0.1839031770998422 1.0 0.6772893373742845 15 Q13049,Q14203,Q14331,Q9GZZ9 4 +Aplasia hypoplasia of the eyelid 0.4611012385064125 1.328649436837271 0.1839636538364835 1.0 0.6772893373742845 14 Q9H2P0,Q9P2D1,Q8TDP1,Q13428 4 +Fatigable weakness of skeletal muscles 0.5413839929541328 1.3269307878624428 0.1845315787590711 1.0 0.6772893373742845 8 Q14315 1 +Stereotypy 0.3070777258317994 1.3259958773973113 0.1848410629322558 1.0 0.6772893373742845 70 Q9UQN3,P55011,P51608,Q7Z6Z7,Q96N67,Q7Z3K3,Q71SY5,P15311,Q96JM3,Q6PJT7,Q6P1N0,Q9BPU6,Q01082,Q9H2P0,Q12904,P29401,P11166,P67870,P55072,Q14683 20 +Broad neck 0.500262572931303 1.3246765786889023 0.1852784446179085 1.0 0.6772893373742845 11 O60826,Q12830,P62857 3 +Female sexual dysfunction 0.6148238703155715 1.324051878374313 0.1854858158114263 1.0 0.6772893373742845 6 Q9P2D1 1 +Oral ulcer 0.5253694439671112 1.323257722366216 0.1857496860805525 1.0 0.6772893373742845 9 Q5F1R6,P01889,Q8NBM4,Q7Z2Z2,P61011 5 +Facial telangiectasia 0.6685760348230306 1.3232326754767747 0.1857580127984195 1.0 0.6772893373742845 5 Q9UER7 1 +Shoulder dislocation 0.7204556372183368 1.323075373719389 0.1858103133200019 1.0 0.6772893373742845 4 P21333,Q6ZXV5 2 +Abnormal cerebellar vermis morphology 0.2944642149387551 1.3226068338533343 0.185966160443987 1.0 0.6772893373742845 87 Q9P2D1,Q15051,O14802,Q8N201,P98175,Q9UGM6,O60826,Q92785,Q96KP1,Q8NCM8,P07942,O15078,Q96L73 13 +Arnold chiari malformation 0.3673695916900886 1.3216265989780158 0.186292521591624 1.0 0.6772893373742845 27 Q6UX04,O14802,O43709,Q04721,P18583,Q8NFV4,O14974,Q15056,P21333,Q9UIG0,Q15233 11 +Polydactyly 0.3200271877072244 1.3189421031762252 0.187188468979752 1.0 0.6772893373742845 59 Q9P2D1,Q9Y366,Q8NCM8,P98175,O60826,Q9Y2V7,Q13049,Q9H2P0,O15078 9 +Abnormality of neutrophil physiology 0.6669844013512225 1.316042683813614 0.1881597167226492 1.0 0.6783384046626462 5 Q5F1R6,P61011,Q7Z2Z2 3 +Abnormality of male internal genitalia 0.4591740170283949 1.3154273897079207 0.1883663053874087 1.0 0.6784061912948604 14 O60934,Q92878,Q9Y6D9 3 +Expressive language delay 0.5236108542169907 1.3131114282489071 0.1891454034865951 1.0 0.6784300365986755 9 Q6ZRS2,Q96L73 2 +Ureteral stenosis 0.5759071626071555 1.3131023397796555 0.1891484655539614 1.0 0.6784300365986755 7 P21333,Q9UBM7,Q96L73 3 +Lymphangioma 0.8447089899798361 1.3120624272458996 0.1894990719830172 1.0 0.6784300365986755 3 P48735 1 +Hemangiomatosis 0.8447089899798361 1.3120624272458996 0.1894990719830172 1.0 0.6784300365986755 3 P48735 1 +Visceral angiomatosis 0.8447089899798361 1.3120624272458996 0.1894990719830172 1.0 0.6784300365986755 3 P48735 1 +Abnormal size of the palpebral fissures 0.2957658238871261 1.3103227685681846 0.190086668157801 1.0 0.6797390797106238 89 P55011,P51608,Q9UHD8,P38159,Q7Z6Z7,Q9UIG0,O75175,O43709,Q12830,Q8NFV4,Q8WXI9,O14974,P98175,P11274,Q9BPU6,Q15056,P02545,Q01082,Q9H2P0,Q92917,P51610,Q8N201,Q9BZI7,Q96DF8,O94992,Q8N3R9 26 +Thin nail 0.6652145679371589 1.3080474599369916 0.1908572123080691 1.0 0.681193137938247 5 Q96L73 1 +Abnormal blood monovalent inorganic cation concentration 0.4113375736585578 1.3061432208338415 0.1915038572881213 1.0 0.6824527797683282 21 P08397,P35658,P40818,Q9NP58 4 +Elevated tissue non specific alkaline phosphatase 0.810363836824695 1.302053118333958 0.1928982279131741 1.0 0.6856210766495641 2 P55072 1 +Aplasia hypoplasia of the ear 0.316493690275855 1.2953086890360783 0.1952137629511674 1.0 0.6882840337132587 61 Q9P2D1,Q13428,P61254,Q12830,P62913,P62273,P98175,P62081,P62899,P62857,P39019,Q9H2P0 12 +Congenital hepatic fibrosis 0.5343712218442599 1.2879243235626452 0.1977723074900432 1.0 0.6920541512848126 8 Q15051,O15078 2 +Intermittent diarrhea 0.5186134869461263 1.2842779932992887 0.1990447040399057 1.0 0.6934384981874013 9 Q9UER7,P54098,Q4G176,Q8WX93 4 +Abnormal basophil morphology 0.8048511576626222 1.2786628322837117 0.2010158134672448 1.0 0.697859176647303 2 Q01130 1 +Abnormality of chromosome segregation 0.6569286846550411 1.270616165923488 0.2038652329842727 1.0 0.7022696350466385 5 P51608 1 +Cone shaped epiphyses of the phalanges of the hand 0.5311117422030059 1.269794617362168 0.204157798563739 1.0 0.7027565110560707 8 Q6ZRS2,P21333,Q5JRA6,Q9Y366 4 +Long toe 0.5001158350896198 1.2678181262048658 0.204862907528557 1.0 0.7030384327780903 10 O14802 1 +Dyscalculia 0.4908877407570454 1.266884011036895 0.2051967666262033 1.0 0.7030384327780903 11 P09651,P46821,Q9UQN3,P55072,P22626,Q06787,Q96T60,Q96L73 8 +Syncope 0.4908414945217746 1.266598971760733 0.205298720309849 1.0 0.7030384327780903 11 Q99496,Q01130,Q969G3,P02545,Q14315,P0DP25 6 +Telangiectasia of the skin 0.3997565015837925 1.263992143832195 0.2062328467475667 1.0 0.7041616743834993 22 P06748,Q9UER7,O60832,Q9NPE3,Q13043,P02545,P54132,P40818 8 +Abnormal hair whorl 0.3774786142046968 1.2593090176184332 0.207918737356574 1.0 0.7073194527789163 25 P55011,Q12830,Q9BPU6,P02545,Q7Z6Z7,P21333,Q8N3R9,P25490 8 +Abnormal circulating amylase level 0.6009323054507405 1.2566317617678728 0.2088870080432787 1.0 0.7100935818413434 6 Q5F1R6,Q9Y3A5,P61011,Q7Z2Z2 4 +Ureteral obstruction 0.5134343591994428 1.2543994469780693 0.2096968534706271 1.0 0.7112856044364997 9 P21333,Q9UBM7,Q96L73 3 +Subcortical heterotopia 0.5999680046429278 1.2519518901793425 0.2105873950043586 1.0 0.7132646791168114 6 Q9BSJ2,P23258,P07942 3 +Advanced eruption of teeth 0.4964794524588411 1.2460166458909672 0.2127582841023452 1.0 0.7159216120373628 10 O14802,P02545,P21333,Q9H2P0,Q96L73 5 +Hyperorality 0.8268541494347934 1.2426681325808595 0.2139901516779958 1.0 0.7186472232102419 3 Q14203,Q9UQN3 2 +Dimple chin 0.8262046843585198 1.2401466542256958 0.2149211554137244 1.0 0.7204733591065108 3 Q9P2D1 1 +Abnormal number of teeth 0.2862481249366846 1.239305578883003 0.2152323534506295 1.0 0.7204733591065108 84 Q9UBM7,O60832,O95319,Q7Z6Z7,Q9UIG0,Q9P2D1,Q8NFV4,Q9NW13,P06748,Q9NPE3,Q15056,P02545,O75369,P54132,Q9GZZ9,Q6ZRS2,Q96L73,Q5F1R6,Q13428,O14802,Q9Y366,P21333,Q14683 23 +Hypopituitarism 0.3383566508194363 1.2392879790568698 0.2152388688559194 1.0 0.7204733591065108 40 Q96ST3,Q5F1R6,Q9P2D1,O14802,Q99496,O75369,Q9NW13,Q9H2P0,Q14683 9 +Abnormal neural tube morphology 0.3276391958838004 1.2385080830181707 0.2155277268283213 1.0 0.7205448536483519 46 Q96ST3,O43709,Q8NFV4,Q15056,Q9Y2W2,Q14807,Q14692,O75369,P21333,Q15149,Q9UIG0,O15078,Q14683 13 +Micronodular cirrhosis 0.5613698837498571 1.2377911543773543 0.2157935091756235 1.0 0.7205733208443471 7 Q9NWH9 1 +Abnormal parietal bone morphology 0.6491401526591369 1.2354404309754805 0.2166666334074474 1.0 0.7218084237900041 5 O14802 1 +Neoplasm of the pancreas 0.3564588429184347 1.2352408570787687 0.2167408776306123 1.0 0.7218084237900041 29 P06748,O60885,O60832,O60934,P54277,Q6P1J9,Q92878,Q9NPE3,Q99496,Q8WX93,Q9NYB0,P11802,Q01844 13 +Abnormal urinary electrolyte concentration 0.408539037029068 1.2348843942154706 0.2168735322454633 1.0 0.7218084237900041 20 P78347,Q01968,O43709,Q6P1J9,Q8NFV4,Q15056,Q14697,Q9UNF1,O00443,Q9UIG0,O14745 11 +Aplasia hypoplasia involving the metacarpal bones 0.3574506451569268 1.234563560164566 0.2169929778426158 1.0 0.7218084237900041 28 Q9Y448,Q14683,Q9Y366,O75369,P21333,Q6ZRS2,Q6UX04 7 +Acidemia 0.4467603377809676 1.2303056256450429 0.2185826784711626 1.0 0.7232885212272898 14 O14678,P51610,P48735 3 +Hypoamylasemia 0.6479244632234129 1.2299514744375877 0.2187152768016214 1.0 0.7232885212272898 5 Q5F1R6,P61011,Q7Z2Z2 3 +Abnormality of the extraocular muscles 0.6980143408714732 1.2279856864933552 0.2194523412070443 1.0 0.7232885212272898 4 P54098,P43243,Q9BVA1 3 +Abnormal soft palate morphology 0.2936122453297511 1.2278590156017457 0.219499897033556 1.0 0.7232885212272898 74 Q9P2D1,Q13428,P61254,O14802,P18583,P62273,P62913,P62081,Q96DF8,P62899,P62857,P39019,P21333,Q14683 14 +Pulmonary carcinoid tumor 0.8214539772768306 1.2217099608914683 0.2218173281116846 1.0 0.724669289335073 3 Q9UER7 1 +Carcinoid tumor 0.8214539772768306 1.2217099608914683 0.2218173281116846 1.0 0.724669289335073 3 Q9UER7 1 +Reduced natural killer cell count 0.6460460865076202 1.221471492098319 0.221907552985541 1.0 0.724669289335073 5 Q9Y448 1 +Abnormal natural killer cell morphology 0.6460460865076202 1.221471492098319 0.221907552985541 1.0 0.724669289335073 5 Q9Y448 1 +Abnormal aortic arch morphology 0.4734687495675651 1.2179374774562262 0.2232477329451201 1.0 0.7257885073380095 12 Q9P2D1 1 +Primary microcephaly 0.4215207108130189 1.2154240642047525 0.2242043945167269 1.0 0.7257885073380095 17 Q9UQE7,Q99496,P51608,Q03252,Q9UN37 5 +Distal upper limb muscle weakness 0.5923531750082518 1.2150041428285492 0.2243645113067178 1.0 0.7257885073380095 6 Q14315 1 +Pectus excavatum 0.2836814073570294 1.2145613127204378 0.2245334517602291 1.0 0.7257885073380095 83 Q9Y281,Q9NWH9,O60885,P51608,P24928,Q15437,Q7Z6Z7,Q9UIG0,Q8NFV4,P98175,Q9UQE7,Q15056,P02545,O75369,Q96L73,Q8N201,Q9Y366,Q9Y2W2,Q9BZI7,O60828,P21333,Q14683 22 +Male reproductive system neoplasm 0.4113440123661583 1.2138284562360937 0.2248132374565314 1.0 0.7257885073380095 19 O60934,Q92878,Q9Y6D9 3 +Ulnar deviation of the hand 0.644120647455104 1.2127805545631427 0.2252137318607827 1.0 0.7257885073380095 5 P21333,Q9NW13 2 +Hip subluxation 0.5564652302220537 1.212393931102192 0.2253616229308646 1.0 0.7257885073380095 7 Q03252,Q14807,Q9UBM7 3 +Bifid tongue 0.6436626313969894 1.2107134328561686 0.2260052523624471 1.0 0.7257885073380095 5 Q8NCM8 1 +Chronic lung disease 0.5203105812952883 1.209740977056642 0.2263783008281104 1.0 0.7257885073380095 8 P50454,Q14683 2 +Hypoplastic ilia 0.4900044839727149 1.207216077966472 0.2273489401707995 1.0 0.7257885073380095 10 P39019,Q15910,O75369,O14802 4 +Shoulder girdle muscle atrophy 0.6428738417687382 1.2071536958882187 0.2273729590222339 1.0 0.7257885073380095 5 Q13049,Q14331 2 +Dilated third ventricle 0.6428097103298274 1.2068642898153228 0.2274844121465689 1.0 0.7257885073380095 5 P26358,Q71SY5 2 +Abnormal muscle fiber type distribution 0.4715630867591582 1.205859320284305 0.2278717381663697 1.0 0.7257885073380095 12 Q9Y281 1 +Anosmia 0.6425127625673107 1.2055242798079793 0.2280009707352255 1.0 0.7257885073380095 5 Q9P2D1 1 +Bifid scrotum 0.5903836888250156 1.2054513754191851 0.2280290984965556 1.0 0.7257885073380095 6 Q9P2D1,Q9UBM7 2 +Tracheal stenosis 0.6919714393555243 1.2024051961263391 0.2292065769838869 1.0 0.7276241443365171 4 O75369 1 +Abnormality of lower limb metaphyses 0.5189233918876495 1.202033002606149 0.2293507418002374 1.0 0.7276241443365171 8 Q15910 1 +Increased body weight 0.3142784538085708 1.201934986916704 0.2293887177647939 1.0 0.7276241443365171 116 Q96ST3,O43837,O60885,P51608,P38159,Q13049,Q9NQ48,Q9UIG0,P40818,O15078,Q9P2D1,Q7Z3K3,O43709,Q12830,Q8NFV4,P25490,Q9UQE7,Q99496,Q15056,P02545,Q9HCK8,P54132,Q01082,Q9H2P0,Q96T60,O43395,P42345,P51610,Q9BZI7,Q14683 30 +High hypermetropia 0.456875446960365 1.2003805500956115 0.2299915791443165 1.0 0.728045550601934 13 O43709,Q8NFV4,Q9Y366,Q15056,Q9UIG0 5 +Aplasia hypoplasia of the distal phalanges of the hand 0.3391230016725262 1.1948653907240034 0.2321396267909936 1.0 0.7298231933116801 37 Q9Y448,P42345,P51610,P51608,Q9Y366,P02545,O60826,O75369,P21333,Q6UX04 10 +Thyroid carcinoma 0.3975644210829586 1.193683537284081 0.2326017826177016 1.0 0.7298231933116801 21 P42771,Q96GM5,Q8TAQ2,Q969G3,Q6P1J9,Q05655,Q15437,Q92785,Q12824,O14497 10 +Thick corpus callosum 0.8141714915908451 1.193476369199602 0.2326828615020666 1.0 0.7298231933116801 3 Q7LBC6,Q15233 2 +Abnormal metaphyseal trabeculation 0.5879051562577147 1.1934321959346774 0.2327001520817326 1.0 0.7298231933116801 6 P06748,Q9NPE3,O60832 3 +Abnormal circulating sex hormone concentration 0.3912996436678814 1.1932467508158886 0.2327727501331358 1.0 0.7298231933116801 22 Q9P2D1,O14802,Q99496,Q969G3,P82650,Q15031,Q9NW13,P51809 8 +Abnormality of the distal phalanx of the thumb 0.5877951884517799 1.192899003486141 0.2329089295634219 1.0 0.7298231933116801 6 Q9Y448,O75369 2 +Aplasia hypoplasia of the 5th finger 0.4261045540866684 1.1922341748017975 0.2331694367661132 1.0 0.7299512583975385 15 O75147,Q96GM5,Q9UQE7,Q8TAQ2,Q969G3,Q92785,Q12824,O00443,O14497 9 +Protruding ear 0.319261346580323 1.1915925709972597 0.2334210393756708 1.0 0.7299512583975385 48 Q9Y448,O75147,P18583,Q8NFV4,O14974,Q15056,Q8N201,Q9BZI7,Q7Z6Z7,Q9BSJ2,P54132,Q01082,O60828,P21333,Q9H2P0,Q9UIG0 16 +Abnormal granulocyte count 0.287273478965079 1.188572639417075 0.2346078798083413 1.0 0.7309522514601129 76 Q9Y3C6,P62913,Q9Y4L1,Q9P2D1,Q13043,P06748,P61254,Q14980,P62273,P62081,Q9H078,P62857,P46777,P62899,P39019,Q5F1R6,O14678,Q01130,Q6UN15 19 +Palpebral edema 0.5867506760174545 1.187834902133561 0.2348984607984749 1.0 0.7311273592300825 6 Q9Y448,Q14331 2 +Chronic infection 0.4862992544415373 1.1850292124697273 0.2360058970338192 1.0 0.7335915742582997 10 P06748,Q14980,Q6UN15 3 +Ileus 0.6875544321563232 1.1837193925979752 0.2365241597750689 1.0 0.73422028755828 4 P08397,Q01844 2 +Abnormal brain positron emission tomography 0.5851075316636415 1.1798697950497514 0.2380520048138334 1.0 0.7350549049179365 6 Q99496,P55072,Q969G3,Q9UQN3 4 +Abnormal myeloid cell morphology 0.6866114810659552 1.179731847270173 0.2381068831608801 1.0 0.7350549049179365 4 Q02241,P22314 2 +Uterus didelphys 0.8101796833817128 1.178017227301447 0.2387897383738506 1.0 0.7350549049179365 3 O14974 1 +Abnormal ileum morphology 0.4390593891385076 1.1775862277919216 0.2389616030065493 1.0 0.7350549049179365 14 P51610,P51608,O14974 3 +Bone marrow hypocellularity 0.3524482797147532 1.177438191220161 0.239020653948583 1.0 0.7350549049179365 27 P06748,Q5F1R6,P62263,P61254,O60934,O60832,Q9NPE3,Q7Z2Z2,Q14739,Q9UJV9,Q9H078,P61011,Q05655 13 +Abnormal thumb morphology 0.3224783209306612 1.1770746759295956 0.2391657017938282 1.0 0.7350549049179365 128 Q96ST3,Q9UBM7,O60885,P55011,P18583,P62913,Q7Z6Z7,Q03252,Q9UIG0,O15078,Q15233,Q9P2D1,Q9Y448,O75175,Q12830,Q8NFV4,Q15910,Q9UQE7,P61254,Q9BPU6,Q15056,P62273,P62081,O75369,P62899,P62857,P46777,P39019,Q9H2P0,Q92917,Q96L73,Q6ZRS2,O60828,P21333,Q8NCM8,Q8N3R9,Q14683 37 +Abnormality of fibula morphology 0.4530891915495966 1.175485138048175 0.2398006796272613 1.0 0.735061845796757 13 Q8NCM8,O75369,Q9NWH9 3 +Moderate sensorineural hearing impairment 0.5138287040857604 1.173738022309473 0.2404999755970012 1.0 0.7354926109808257 8 P51610,P51608 2 +Abnormal rib ossification 0.6847766133480283 1.171974262546266 0.2412073895276032 1.0 0.7354926109808257 4 Q5F1R6,P61011,Q14739 3 +Lower limb metaphyseal irregularity 0.6847766133480276 1.1719742625462632 0.2412073895276043 1.0 0.7354926109808257 4 Q5F1R6,P61011,P26373 3 +Reduction of neutrophil motility 0.6847766133480275 1.1719742625462628 0.2412073895276045 1.0 0.7354926109808257 4 Q5F1R6,P61011,Q7Z2Z2 3 +Proximal femoral epiphysiolysis 0.6847766133480275 1.1719742625462628 0.2412073895276045 1.0 0.7354926109808257 4 Q5F1R6,P61011,Q7Z2Z2 3 +Deformed rib cage 0.6847766133480275 1.1719742625462628 0.2412073895276045 1.0 0.7354926109808257 4 Q5F1R6,P61011,Q7Z2Z2 3 +Stereotypical hand wringing 0.6846652981130329 1.1715037104381874 0.2413963672671391 1.0 0.7355861761904232 4 P51608 1 +Subcortical band heterotopia 0.6343406652779495 1.1686667392012535 0.2425379276366199 1.0 0.7361189560636199 5 Q9BSJ2,P23258,P07942 3 +Renovascular hypertension 0.5128411046837393 1.1682559827416064 0.2427035248074003 1.0 0.7361189560636199 8 Q8NFV4,Q15056,Q9UIG0 3 +Neoplasm of the adrenal gland 0.4516482081382647 1.1660167787664324 0.2436076616928186 1.0 0.7361189560636199 13 P48735 1 +Secondary amenorrhea 0.4145410000676546 1.1635430963993232 0.2446092233751142 1.0 0.7362040550674586 17 Q9P2D1,P29401,Q12830,P54098,P02545,P82650 6 +Abnormal mitochondrial morphology 0.4824894364527736 1.1622327029779984 0.2451409541141966 1.0 0.7368499442229444 10 Q9GZY8,Q7Z406,P55072 3 +Pterygium 0.4644720725106667 1.1609583446724825 0.2456588398504868 1.0 0.7369765195514606 12 Q9NPE3,Q15149,Q96AY3 3 +Mitral valve prolapse 0.3585238993236501 1.1575327054256277 0.247054785146767 1.0 0.7395015222772513 26 O43709,P36543,Q8NFV4,Q15056,P54098,P02545,P46777,P21333,Q9UIG0,Q02809 10 +Renal cell carcinoma 0.3803882755110818 1.1565075962079363 0.247473594280154 1.0 0.7395561367330391 23 Q92733,Q99496,Q15437,Q9NWH9 4 +Reticulocytosis 0.4207241764103333 1.1538578061898914 0.248558470184971 1.0 0.7399431204033058 15 Q15437,Q9NP58 2 +Episodic tachypnea 0.4807036419284495 1.1515540195010878 0.2495043851668434 1.0 0.7413343208889525 10 P51608,O15078 2 +Arterial stenosis 0.4168638535919974 1.1510863133201177 0.2496967280959277 1.0 0.7414317542886747 16 Q8N1G0,P78347,O43709,Q8NFV4,Q15056,P31153,P02545,P34913,Q9UIG0 9 +Radioulnar synostosis 0.3860360066446584 1.1493301766531103 0.2504198593779234 1.0 0.7417555915013693 22 Q9UQE7,P61254,O60885,Q8NFV4,Q15056,Q9UIG0,Q14683 7 +Abnormal ureter physiology 0.3091256194422112 1.1490312884371356 0.2505430792225194 1.0 0.7417555915013693 56 Q9P2D1,Q9UBM7,Q9UQE7,O14802,O60885,Q14683,Q12830,Q8NFV4,P62913,Q15056,P21333,Q9UIG0,Q96L73,P25490 14 +Absence of secondary sex characteristics 0.6299501064028232 1.1488838196437596 0.2506038903931891 1.0 0.7417555915013693 5 Q9P2D1,P51809 2 +Impaired distal vibration sensation 0.4797046292285142 1.1455822424090705 0.2519680482471014 1.0 0.7438980433318171 10 Q5TAQ9,P54098,P55072,Q9BRK0,P20700 5 +Granulocytopenia 0.6782221647843758 1.144283212841111 0.2525062028970681 1.0 0.7450135395953497 4 P62857,Q9Y4L1 2 +Focal impaired awareness seizure 0.3913793839173137 1.1433535796294696 0.2528918175294028 1.0 0.7456778401390449 21 Q7Z3K3,P42345,Q96JM3,P19022,Q96N67,Q96L73 6 +Nasolacrimal duct obstruction 0.5082602090471964 1.1428428082497069 0.2531038615722898 1.0 0.7458298317859422 8 Q9Y448,Q13428,Q9UQE7,P25490 4 +Cellular immunodeficiency 0.4704490435130687 1.1410891428620715 0.2538328289089837 1.0 0.7470304977454385 11 P06748,Q9NRZ9,Q9NPE3,O60832,Q15437 5 +Abnormal tricuspid valve physiology 0.3783263622857574 1.138875316754129 0.2547551620979007 1.0 0.7477571145051426 23 Q9UER7,Q99496,P36543,P19022,Q14315,P39019,P21333 7 +Abnormality of the diaphragm 0.3466101034902294 1.138565836813896 0.2548842843503649 1.0 0.7477571145051426 29 Q96ST3,Q9UBM7,Q9UQE7,O60885,P62857,Q7LBC6,P21333,Q14683 8 +Lipoatrophy 0.3845889452494007 1.1372767577552816 0.2554226077869221 1.0 0.7486296899909518 22 O14802,P02545,Q9NW13,P21333,Q03252,P18206 6 +Abnormal lacrimal duct morphology 0.4777949411830931 1.134171266062101 0.2567227144457606 1.0 0.7501842062600173 10 Q9Y448,Q13428,Q9UQE7,P25490 4 +Abnormal internal genitalia 0.3235666592790315 1.1338475518417437 0.2568585005750856 1.0 0.7501842062600173 133 Q9UBM7,O60885,O60832,P54098,Q15437,P20585,Q13049,Q9NQ48,P48735,Q9UIG0,O15078,P40818,Q03252,Q9P2D1,O60934,Q8NFV4,O14974,Q92878,Q01844,P06748,Q9Y6D9,Q9UQE7,Q9NPE3,Q15056,P02545,P54132,O75874,Q6ZRS2,Q15051,Q13428,Q8NCM8,Q14683 32 +Multiple renal cysts 0.4059529745675785 1.1330536308663988 0.2571917320813148 1.0 0.7501842062600173 18 P14314,O43709,Q8NFV4,Q15056,O75369,Q9UIG0 6 +Subcutaneous nodule 0.4003864513735951 1.128696088445687 0.2590260599445879 1.0 0.7537220416797121 19 O75874,Q15437,P48735 3 +Glossoptosis 0.5730246851869075 1.121363119288858 0.2621333281227676 1.0 0.7593084637098836 6 P98175,Q13428 2 +Abnormal upper limb bone morphology 0.3047843191393714 1.119364554892241 0.2629846459434872 1.0 0.7599311148322477 111 Q9UBM7,O60885,P55011,Q96AY3,P53597,Q7Z6Z7,Q9UIG0,Q6UX04,Q15233,Q9P2D1,O75147,O75175,Q9Y448,O43709,Q12830,Q8NFV4,Q8WXI9,P98175,Q15910,Q9UQE7,P61254,Q9BPU6,Q15056,P02545,O75369,P39019,Q9H2P0,Q6ZRS2,Q96L73,O14802,Q9Y366,O60828,P21333,Q8NCM8,Q8N3R9,Q14683 36 +Achilles tendon contracture 0.4578399396454943 1.1190418991153506 0.2631222646363431 1.0 0.7599311148322477 12 Q8TD16,P02545,Q15149,P50402 4 +Open bite 0.4038671436224775 1.117261303395292 0.2638826158427307 1.0 0.7607087567128845 18 Q13428,P78347,O43709,Q04721,Q8NFV4,Q15056,Q13620,O15160,Q9UIG0 9 +Deep set nails 0.6713132784972482 1.1151350412108938 0.2647925574120473 1.0 0.7609715610969598 4 Q96L73 1 +Sandal gap 0.3403316074589621 1.1130112015196474 0.2657036186698636 1.0 0.7622766076141606 32 Q15910,Q12830,Q9Y366,O75369,Q9H2P0,Q96L73 6 +Abnormal thyroid morphology 0.3169320970429388 1.1118144913174388 0.2662179198584811 1.0 0.7622766076141606 46 Q9P2D1,Q13428,P20585,O75874,P48735 5 +Eyelid myoclonus 0.4884201165436812 1.1103736811496896 0.2668380345729511 1.0 0.7630746748680023 9 P00374 1 +Oculogyric crisis 0.4733760309010132 1.1077921708878435 0.2679515820487128 1.0 0.7640043115729604 10 Q96JM3 1 +Occipital encephalocele 0.5699802080325884 1.106644103381767 0.2684478311577041 1.0 0.7640043115729604 6 P07942 1 +Periorbital fullness 0.3863806626120664 1.1027934160979829 0.2701168879337468 1.0 0.7677267145126123 21 P51610,P51608,Q8WXI9,P38159,Q9BZI7,O75179,P25490 7 +Abnormality of neutrophil morphology 0.5690586189322834 1.1021907149139842 0.2703787677804867 1.0 0.7680013043251357 6 P35579,P62263,Q14739 3 +Embryonal renal neoplasm 0.4411884049172243 1.0974236335850724 0.2724562468491105 1.0 0.7734295535172978 13 Q6P1J9,P51809,P54132,Q8IY37,Q96L73,P26367 6 +Zollinger ellison syndrome 0.7888307468053966 1.0955962118611458 0.2732555202200304 1.0 0.7750216386598732 3 Q9UER7 1 +Renal cyst 0.2830380468430931 1.0942831905758288 0.2738307952689482 1.0 0.7750216386598732 75 Q9UBM7,O60885,P20585,Q13049,Q9NQ48,Q9UIG0,O15078,Q6UX04,O43709,Q04721,Q8NFV4,Q9UQE7,Q15056,O75369,Q6ZRS2,P29401,P14314,Q8NCM8,Q14683 19 +Small earlobe 0.4993460784724602 1.0934767230222209 0.2741845435672114 1.0 0.7750216386598732 8 P98175 1 +Decreased circulating androgen concentration 0.4625109033149638 1.0924036208104049 0.2746557322164862 1.0 0.7758815730152046 11 Q9P2D1,Q99496,Q969G3,Q9NW13,Q8IY37,P51809 6 +Teratoma 0.7865768170399575 1.086924810434236 0.2770700405048711 1.0 0.7762816178432331 3 P20585 1 +Epistaxis 0.4079499052729718 1.0864436924611087 0.2772827398884954 1.0 0.7762816178432331 16 P49257,P35579,Q14980 3 +Abnormal 3rd finger morphology 0.6644453260023517 1.08620896369677 0.2773865524370902 1.0 0.7762816178432331 4 Q9Y448,Q14683 2 +Proximal muscle weakness in upper limbs 0.4251650218590197 1.0827985818261108 0.2788978351768039 1.0 0.77840134538535 14 P08397,P02545,P55072,P50336,P50402 5 +Neoplasm of the thyroid gland 0.3406026134069045 1.0799072361754198 0.2801834906269873 1.0 0.7810513982865088 29 P42771,Q96GM5,Q8TAQ2,Q969G3,P54277,Q6P1J9,O14497,P02545,Q15437,P20585,Q92785,Q12824,Q05655 13 +Hypoplasia of the radius 0.4827037996015789 1.077588142383504 0.281217596226349 1.0 0.7821984449571184 9 P98175,P61254 2 +Eclabion 0.3257052897623155 1.074616264150595 0.2825465671274347 1.0 0.7829420974604587 38 P46821,O75147,Q7L2E3,O43709,P51608,Q8NFV4,Q15056,Q96JM3,Q9Y366,Q9H2P0,Q96N67,Q15042,Q9UIG0 13 +Radial deviation of the hand or of fingers of the hand 0.4237440258145781 1.0731375286425435 0.2832094149810455 1.0 0.7836462418754282 14 P21333,Q15910,O75369 3 +Fatty replacement of skeletal muscle 0.4816790199760892 1.0717180080969244 0.2838467098495922 1.0 0.7836462418754282 9 O75190,Q7Z406 2 +Abnormal epiphysis morphology of the phalanges of the hand 0.4812359420832831 1.069180727337055 0.284988241259144 1.0 0.7846788735953957 9 Q6ZRS2,P21333,Q5JRA6,Q9Y366 4 +Porencephalic cyst 0.5619445241762456 1.0678517957170983 0.285587369557257 1.0 0.7846788735953957 6 P07942 1 +Abnormal scalp morphology 0.315582538132556 1.0678373029229389 0.2855939080994085 1.0 0.7846788735953957 128 Q96ST3,O60885,O60832,P62913,O75179,Q96N67,Q92785,Q7Z6Z7,O15160,O15344,Q6UX04,Q9Y448,O75175,Q71SY5,O60934,Q969G3,Q04721,P19022,P46778,Q9UQE7,P61254,Q9NPE3,P62273,O60826,P62081,P02545,P62899,P62857,P46777,P39019,Q15042,Q15149,P61353,Q9H2P0,Q96L73,Q6ZRS2,Q13428,O14802,Q9Y2W2,P78536,Q14683 41 +Multifocal seizures 0.6111454860468983 1.0643756663529895 0.2871585526462761 1.0 0.7873917209025891 5 Q9UGM6 1 +Hypoplastic facial bones 0.3967868899800045 1.0637938949515595 0.2874220775905132 1.0 0.7875236216672105 18 Q9P2D1,Q13428,O43709,Q04721,Q8NFV4,Q15056,Q9UIG0 7 +Proximal femoral metaphyseal abnormality 0.6590063835137108 1.063342394229503 0.2876267062708864 1.0 0.7875236216672105 4 Q5F1R6,P61011 2 +Broad face 0.6587308197447812 1.0621849174597005 0.2881517455499014 1.0 0.7875236216672105 4 O75369 1 +Overfriendliness 0.5271769092737533 1.061184330756554 0.2886061389497008 1.0 0.7875236216672105 7 Q8NFV4,Q15056,Q9UIG0 3 +Nystagmus induced head nodding 0.5271769092737533 1.061184330756554 0.2886061389497008 1.0 0.7875236216672105 7 Q8NFV4,Q15056,Q9UIG0 3 +Phonophobia 0.5271769092737533 1.061184330756554 0.2886061389497008 1.0 0.7875236216672105 7 Q8NFV4,Q15056,Q9UIG0 3 +Flat cornea 0.5271769092737533 1.061184330756554 0.2886061389497008 1.0 0.7875236216672105 7 Q8NFV4,Q15056,Q9UIG0 3 +Abnormal mitochondrial shape 0.6101493716471575 1.059911733365952 0.2891847571639845 1.0 0.7880990371203447 5 Q7Z406 1 +Macroorchidism 0.6096486954047318 1.0576685970331263 0.2902065567787766 1.0 0.7889541316037404 5 Q9BZI7,P51608 2 +Episodic ataxia 0.6092035740180948 1.055674681755206 0.2911168680988969 1.0 0.7889541316037404 5 P11166 1 +Sparse lateral eyebrow 0.4922479405063196 1.0542727253784283 0.2917580722220689 1.0 0.7889541316037404 8 Q92643,O60828,Q9Y2V7 3 +Low levels of vitamin d 0.4629522219910112 1.0457390692185888 0.2956815194394573 1.0 0.7924049728478211 10 Q5F1R6,Q01968,Q7Z2Z2,P62913,Q13043,Q9Y3A5,P61011 7 +Aplasia hypoplasia of the distal phalanx of the thumb 0.7751852248849657 1.0432067545538366 0.296852545818802 1.0 0.7929620297925474 3 Q9Y448 1 +Juvenile cataract 0.5229516203766795 1.039476064429088 0.2985833843086696 1.0 0.7960510538625287 7 Q9H2P0,P51608,Q01082 3 +Exaggerated cupid s bow 0.5226414750434819 1.0378840931740805 0.2993240199653408 1.0 0.7963152802780696 7 Q71SY5,Q96KP1 2 +Molar tooth sign on mri 0.5221529310699032 1.0353768284672855 0.3004929627195638 1.0 0.7963152802780696 7 O15078 1 +Female external genitalia in individual with 46 xy karyotype 0.7466923925027522 1.0338945699064817 0.3011854538271221 1.0 0.7963152802780696 2 P51809 1 +Abnormal sex determination 0.7466923925027522 1.0338945699064817 0.3011854538271221 1.0 0.7963152802780696 2 P51809 1 +Hypoplasia of the vagina 0.7466923925027522 1.0338945699064817 0.3011854538271221 1.0 0.7963152802780696 2 P51809 1 +Testicular dysgenesis 0.7466923925027522 1.0338945699064817 0.3011854538271221 1.0 0.7963152802780696 2 Q9H0U9 1 +Ovarian gonadoblastoma 0.7466923925027522 1.0338945699064817 0.3011854538271221 1.0 0.7963152802780696 2 P51809 1 +Bronchitis 0.521590626154496 1.0324916638008104 0.3018418508334268 1.0 0.7965128227273904 7 O60934,P54132,O15533 3 +Abnormal aggressive impulsive or violent behavior 0.2956872947901859 1.031664461086086 0.3022293314676312 1.0 0.7968471909169446 107 Q96ST3,P23378,Q9UBM7,Q9UQN3,P51608,P53597,Q92785,Q15233,P17480,Q12830,Q8WXI9,Q96JM3,P19022,Q13409,Q9BPU6,Q9UGM6,Q7LBC6,Q01082,Q9H2P0,Q6ZRS2,Q96L73,Q96T60,P29401,P11166,Q96DF8,P55072 26 +Aphthous ulcer 0.4878363669801905 1.0299652166776658 0.303026334118194 1.0 0.7968471909169446 8 Q8NBM4,P61011,Q05655 3 +Ethylmalonic aciduria 0.5531077485258078 1.0253096340502963 0.3052171114425557 1.0 0.7986170703116872 6 P54098,P53597 2 +Dyslexia 0.4728934895640043 1.0215017918279734 0.3070167605978637 1.0 0.8012049482145635 9 P11166,Q9UQN3,P55072,Q01082,Q96T60 5 +Blue irides 0.4588050661123028 1.0211340424453617 0.3071909364066305 1.0 0.8012049482145635 10 Q8NFV4,Q15056,Q9UIG0 3 +Abnormality of the nasal tip 0.2941089278848074 1.021029141665225 0.3072406321752425 1.0 0.8012049482145635 106 P51608,P36543,P10586,P38159,Q7Z6Z7,Q96N67,Q92785,Q7Z3K3,Q9Y448,Q12830,Q8WXI9,Q9Y2V7,Q9BSJ2,Q96KP1,P25490,Q13409,Q9UQE7,P02545,O75369,Q7LBC6,Q01082,Q15042,Q9H2P0,Q6ZRS2,P51610,Q8N201,Q9BZI7,Q96DF8,O60828,P21333 30 +Abnormality of the small intestine 0.2979577119639763 1.0186325566662808 0.3083774420491036 1.0 0.802498118515776 58 Q5F1R6,Q9P2D1,P51610,P51608,O14974,Q9Y2W2,Q9BZI7,P98175,Q7LBC6,P78536,P21333,Q6ZRS2 12 +Abnormal nipple morphology 0.295779620792197 1.0170483794979612 0.309130415113942 1.0 0.802498118515776 61 Q9P2D1,Q9Y448,Q9UBM7,Q15910,Q9UQE7,O14678,P10586,P19022,O60826,Q96KP1,Q92974,Q9H2P0,Q14683 13 +Limited hip movement 0.3946998252401504 1.01699471197389 0.3091559450132655 1.0 0.802498118515776 17 Q8TD16,Q96AY3 2 +Streak ovary 0.5184288001158117 1.0162818834910197 0.3094951731220452 1.0 0.802498118515776 7 O14974,P82650,Q8IY37,P26367,P51809 5 +Hand polydactyly 0.3154312394927007 1.0159635240060756 0.3096467567046304 1.0 0.802498118515776 42 Q9P2D1,P98175,O60826,Q13049,Q8NCM8,O15078 6 +Abnormal fallopian tube morphology 0.4718485935856606 1.0155438134502504 0.3098466724912008 1.0 0.802498118515776 9 Q92878 1 +Elfin facies 0.4842056658214878 1.0099988607666803 0.3124958358520078 1.0 0.8064589054917577 8 Q8NFV4,Q15056,Q9UIG0 3 +Neuroendocrine neoplasm 0.4489930009486411 1.009880137773974 0.3125527197741888 1.0 0.8064589054917577 11 Q9UER7,P02545,P36957,P25490 4 +Abnormal proximal phalanx morphology of the hand 0.6439220065711407 1.0001552884721527 0.3172353631696869 1.0 0.8108820005280417 4 P42345,O75369 2 +Fibrous tissue neoplasm 0.3836643707945827 0.9997988402036252 0.317407867217669 1.0 0.8108820005280417 19 Q99496,Q969G3,Q6P1J9,Q96JJ3,Q15437,Q01082,P21333,Q05655 8 +Abnormal left atrium morphology 0.7623596716384404 0.9942338857452891 0.3201090145664849 1.0 0.8137655687993529 3 Q14315 1 +Left atrial enlargement 0.7623596716384404 0.9942338857452891 0.3201090145664849 1.0 0.8137655687993529 3 Q14315 1 +Caesarian section 0.6421620296395145 0.9928085074456238 0.3208032832191176 1.0 0.8137655687993529 4 O14802 1 +Pancreatic hypoplasia 0.5462402630097802 0.9923524434909368 0.3210256289903537 1.0 0.8137655687993529 6 Q5F1R6,P61011,Q7Z2Z2 3 +Abnormal lateral ventricle morphology 0.3200315346630943 0.9920992681596882 0.3211491035117653 1.0 0.8137655687993529 37 Q71SY5,Q15910,Q9BVA1,P18583,Q9ULH0,Q96JM3,O14974,Q9UGM6,P67870,Q8IY37,Q15042,O94979 12 +Distal muscle weakness 0.2840837148375449 0.9914235913244224 0.3214787853911605 1.0 0.8137655687993529 70 P55084,Q14203,Q71SY5,Q5TAQ9,Q8TD16,P43243,P22314,P11047,P08397,P54098,Q7Z406,P02545,P18887,Q14315,P55072,Q15149,Q96T60 17 +Low posterior hairline 0.3198937447200555 0.9906525397614774 0.3218552732022952 1.0 0.8137655687993529 37 Q9Y448,Q9UQE7,O60885,Q9Y2W2,P19022,Q7Z6Z7,O60826,Q15042,Q6ZRS2,Q14683 10 +Impaired glucose tolerance 0.5944881376347668 0.9899503650868988 0.3221983802053869 1.0 0.8137655687993529 5 P40818 1 +Abnormality of the columella 0.3944873791317543 0.9894709855533134 0.3224327587841737 1.0 0.8137655687993529 16 Q6ZRS2,P36543,Q7LBC6,Q6UX04 4 +Proximal muscle weakness in lower limbs 0.3722433807236761 0.9888645783057998 0.3227294031448746 1.0 0.8137655687993529 21 P08397,P54098,Q14315,P02545,Q13049 5 +Deviation of the hallux 0.3176387235307466 0.9884247369275304 0.322944677584096 1.0 0.8137655687993529 38 O75175,P55011,Q15233,Q12830,Q8NFV4,P25490,Q15056,Q9BPU6,Q7Z6Z7,Q8N3R9,Q9UIG0,Q6UX04 12 +Upper limb amyotrophy 0.4244148993944555 0.9881477962454916 0.3230802704976088 1.0 0.8137655687993529 13 P43243,Q14315,Q14203 3 +Short attention span 0.3224090418626355 0.9817764099929386 0.3262100122456872 1.0 0.8180277538421892 145 Q96ST3,Q9UBM7,O60885,P55011,P51608,P53597,O95319,O75179,Q7Z6Z7,Q9UIG0,Q9P2D1,O75175,O43709,O60934,Q12830,Q8NFV4,P15311,O14974,P19022,Q6PJT7,Q6P1N0,P25490,Q13409,P11274,Q9UQE7,Q9BPU6,Q15056,Q7LBC6,Q01082,Q9H2P0,Q9GZZ9,Q6ZRS2,Q96L73,Q5F1R6,Q96T60,P29401,P11166,P51610,Q9Y2W2,Q9BZI7,Q8N3R9,Q14683 42 +Abnormality of the periungual region 0.6395112495900382 0.9817545505398998 0.3262207838170199 1.0 0.8180277538421892 4 P78536 1 +Paronychia 0.6395112495900382 0.9817545505398998 0.3262207838170199 1.0 0.8180277538421892 4 P78536 1 +Dilation of lateral ventricles 0.3312410566217112 0.9812685094925756 0.3264603475009229 1.0 0.8180277538421892 28 Q15910,Q71SY5,Q9BVA1,P18583,Q9ULH0,Q96JM3,Q9UGM6,P67870,Q15042 9 +Abnormal uterus morphology 0.326901791039859 0.978800568015303 0.3276785290118043 1.0 0.8180277538421892 32 Q15437,P20585,O14974 3 +Abnormally ossified vertebrae 0.6387901203653722 0.9787498202944842 0.3277036091170948 1.0 0.8180277538421892 4 Q8NCM8 1 +Absent or minimally ossified vertebral bodies 0.6387901203653722 0.9787498202944842 0.3277036091170948 1.0 0.8180277538421892 4 Q8NCM8 1 +Distal upper limb amyotrophy 0.435475808447992 0.9786065760377012 0.327774408791512 1.0 0.8180277538421892 12 P43243,Q14315,Q14203 3 +Abnormal prolactin level 0.5429620773294136 0.9766576724753138 0.328738656839679 1.0 0.8186207548018792 6 Q99496,Q969G3,Q9NW13 3 +Auditory hallucinations 0.7576418704561041 0.9762956554771832 0.3289179722773081 1.0 0.8186207548018792 3 P19022 1 +Urinary tract neoplasm 0.3130267043091541 0.974517517625217 0.3297996455793304 1.0 0.8186207548018792 41 P42771,Q92733,Q9NWH9,P31040,Q86U86,Q99496,P54277,Q6P1J9,P02545,Q15437,P54132,Q8IY37,P36957,P26367,Q96L73,P51809 16 +Abnormality of complement system 0.6376646541070787 0.9740624732497798 0.3300255208826872 1.0 0.8186207548018792 4 P02545,Q03252 2 +Abnormal monocyte morphology 0.7315325248070514 0.9710777166066812 0.3315095793603726 1.0 0.8189106059092846 2 P61011 1 +Monocytosis 0.7315325248070514 0.9710777166066812 0.3315095793603726 1.0 0.8189106059092846 2 P61011 1 +Disinhibition 0.2936720664295196 0.9709589465305378 0.3315687224548749 1.0 0.8189106059092846 59 P23378,Q9UQN3,P55011,O95319,Q15233,Q71SY5,P17480,P15311,P19022,Q6PJT7,Q6P1N0,Q14203,P26358,Q96N66,Q9BPU6,Q01082,Q12904,Q9GZZ9,Q6ZRS2,P55072 20 +Vasculitis 0.4499842112916137 0.9689966273160404 0.3325468719435063 1.0 0.8189106059092846 10 Q8NBM4 1 +Difficulty running 0.4082928225821206 0.968647499470866 0.3327210954030393 1.0 0.8189106059092846 14 Q8TD16 1 +Hand clenching 0.4635435505488673 0.9683167697939686 0.3328861920728725 1.0 0.8189106059092846 9 Q8TD16,O75369 2 +Chest pain 0.38798407083769 0.9678568002974351 0.3331158917744503 1.0 0.8190420894581327 17 P31040,Q99496,P19022,P50336,P36957,P31153 6 +Laryngeal stenosis 0.7548044880995276 0.9655288737231088 0.3342799811170036 1.0 0.8197356581797972 3 O75369 1 +Irregular hyperpigmentation 0.2821173749735371 0.9633936580222248 0.3353500077511022 1.0 0.8214926125563375 70 Q96ST3,P06748,O60934,O60832,P55011,Q9NPE3,Q12830,P42345,Q9BPU6,Q9NP58,Q9Y2W2,P02545,Q7Z6Z7,Q15437,Q8N3R9,P54132,Q15149,Q6UX04 18 +Germ cell neoplasia 0.4203938763337198 0.9621330921572928 0.3359827530581185 1.0 0.8221372390857181 13 P20585 1 +Abnormality of vitamin b metabolism 0.3905029369993569 0.9609693579679078 0.3365675750458614 1.0 0.8221555894546327 16 P11586,O14678,P51610,P30038,P53597,Q4G176,Q01082,Q05655 8 +Deep philtrum 0.3631587308015039 0.9602534807007688 0.3369276564879491 1.0 0.8221555894546327 22 O60934,Q8N201,Q96L73 3 +Prolonged qtc interval 0.7285005512679529 0.958584788034982 0.3377679589193416 1.0 0.8221555894546327 2 P51608 1 +Sinus bradycardia 0.7285005512679179 0.958584788034837 0.3377679589194147 1.0 0.8221555894546327 2 P02545 1 +Second degree atrioventricular block 0.7285005512679179 0.958584788034837 0.3377679589194147 1.0 0.8221555894546327 2 P02545 1 +Fine hair 0.3865602059604479 0.9574781832919969 0.3383259529675013 1.0 0.8221555894546327 17 Q8WXI9,Q96L73 2 +Inappropriate antidiuretic hormone secretion 0.7282249173098078 0.9574503300606336 0.3383400053047336 1.0 0.8221555894546327 2 P50336 1 +Extra axial cerebrospinal fluid accumulation 0.7279492833517165 0.9563160858427407 0.3389125654154479 1.0 0.8221555894546327 2 Q03252 1 +Recurrent infection of the gastrointestinal tract 0.5385742475677124 0.955692234687552 0.3392277468561731 1.0 0.8221555894546327 6 O60934,P54132,P78536 3 +Broad philtrum 0.4058065279287041 0.9519490787328218 0.341122807359413 1.0 0.8221555894546327 14 Q96GM5,P11166,Q8TAQ2,Q969G3,Q92785,Q01082,Q12824,O14497 8 +Abnormality of salivation 0.3031896817650623 0.9515608552990787 0.3413197418074309 1.0 0.8221555894546327 46 Q14203,Q9UQN3,O14802,P55011,P51608,P51610,P43243,P09417,Q9BZI7,Q01082,Q03252,Q15233 12 +Neonatal alloimmune thrombocytopenia 0.5376645216558887 0.951351854897377 0.3414257917588945 1.0 0.8221555894546327 6 Q6YHK3,Q8TDP1,P17301,P55265 4 +Biparietal narrowing 0.439333966873933 0.9513186212453092 0.3414426569577391 1.0 0.8221555894546327 11 Q9UBM7,Q8WXW3,Q13620,O75845,O15078 5 +Thick vermilion border 0.2723427899882238 0.9497789379571596 0.3422245900396177 1.0 0.8221555894546327 88 Q96ST3,Q96C36,P51608,P38159,Q7Z6Z7,Q96N67,Q92785,Q9UIG0,Q6UX04,Q15233,O75147,O43709,Q969G3,Q8NFV4,Q9NR45,Q9Y2V7,P25490,Q99496,Q9BPU6,Q15056,P62081,Q01082,Q9H2P0,O94979,P11166,P51610,Q9BZI7,P21333,O75845 29 +Melena 0.5853793103447962 0.9494899725517864 0.3423714695838784 1.0 0.8221555894546327 5 Q6YHK3,Q9UER7,Q02241,P17301 4 +Brachydactyly 0.2660254221691857 0.9473100278813152 0.343480822451538 1.0 0.8221555894546327 82 Q96ST3,Q9P2D1,P11166,Q9UQE7,Q14683,Q9Y366,Q9BZI7,O60826,Q15437,O75369,Q92785,Q9H2P0,Q7Z6Z7,P02545,P21333,Q8NCM8,Q6ZRS2,Q6UX04 18 +Infertility 0.4180894067017289 0.9472626051528392 0.3435049809103974 1.0 0.8221555894546327 13 P40818,P51809,P54132,Q9H7N4 4 +Male infertility 0.536546849175549 0.9460224715951382 0.3441371247443316 1.0 0.8221555894546327 6 P54132,P51809 2 +Abnormality of the choanae 0.3126276760346559 0.9454848213051346 0.3444114164053218 1.0 0.8221555894546327 39 Q9P2D1,Q13428,Q9UQE7,O60934,P55011,P62913,Q9Y2W2,P02545,Q14683 9 +Shoulder girdle muscle weakness 0.3848013986224283 0.944679003434813 0.3448227795892737 1.0 0.8221555894546327 17 Q8TD16,O75190,P43243,Q14331,P54098,Q13049 6 +Diastema 0.472188018821545 0.9442055727706726 0.345064608016866 1.0 0.8221555894546327 8 O15347,Q99496,Q8WXI9 3 +Neoplasm of the rectum 0.3806910160455132 0.943310878220786 0.3455219133188012 1.0 0.8221555894546327 18 P20585 1 +Abnormal connection of the cardiac segments 0.2919871284513812 0.9418033340702006 0.346293337893915 1.0 0.8221555894546327 58 Q96GM5,P62913,Q14839,Q92785,Q12824,Q9UIG0,O00192,Q9P2D1,O43709,Q969G3,Q04721,Q8NFV4,P98175,Q15477,O14497,P78347,Q15056,P02545,O60826,P46777,Q6ZRS2,P01889,Q8TAQ2,Q96DF8,O60828 25 +Renal hypoplasia aplasia 0.2806085178789499 0.940752216296933 0.3468318533185945 1.0 0.8221555894546327 97 Q9UBM7,P18583,P62913,O75179,Q9UIG0,Q9P2D1,Q9Y448,O43709,Q04721,Q8NFV4,Q9Y2V7,Q9BU61,O95169,P61254,Q15056,P62273,P62081,P62899,P62857,P46777,P39019,Q92917,Q96L73,Q6ZRS2,Q9Y2W2,O60828,Q8NCM8 27 +Dilated fourth ventricle 0.2936095797585468 0.9361469759978388 0.3491975192740273 1.0 0.8241530544541328 51 Q9P2D1,O14802,Q9UGM6,O60826,Q92785,Q96KP1,Q8NCM8,O15078 8 +Urogenital sinus anomaly 0.7468982630272931 0.9356195493770944 0.3494691054927474 1.0 0.8241530544541328 3 P51809,O14974 2 +Mood swings 0.5821981891278897 0.9354073373552224 0.3495784170167064 1.0 0.8241530544541328 5 Q96DF8 1 +Mediastinal lymphadenopathy 0.5821955457999903 0.9353956465024056 0.3495844396669203 1.0 0.8241530544541328 5 P01889,Q05655,Q01844 3 +Abnormality of the pubic hair 0.5343063823928591 0.9353499632106148 0.3496079744658189 1.0 0.8241530544541328 6 P82650,P51809,Q9H7N4 3 +Muscle fiber inclusion bodies 0.4576746651616019 0.9350987183234166 0.3497374270246502 1.0 0.8241530544541328 9 Q14315 1 +Long palpebral fissure 0.3473615297941811 0.9292826127555271 0.3527426435955725 1.0 0.8291325567974838 24 P51610,P51608,Q8WXI9,Q9BZI7,Q01082,Q9H2P0 6 +Abnormal globus pallidus morphology 0.4430584068536094 0.9282825498474272 0.3532610234509565 1.0 0.8299312315351846 10 Q9BU61,O95169,P24928 3 +Abnormality of frontal sinus 0.7442541551084103 0.9256487757907772 0.3546285364442205 1.0 0.8316517045624902 3 P21333 1 +Absent frontal sinuses 0.7442541551084103 0.9256487757907772 0.3546285364442205 1.0 0.8316517045624902 3 P21333 1 +Abnormal neutrophil count 0.2793284749765403 0.923863542872678 0.3555573665310101 1.0 0.8316517045624902 70 P06748,Q5F1R6,Q9Y3C6,P61254,O14678,Q14980,Q01130,P62913,P62273,Q13043,P62081,Q9H078,P62857,P46777,P62899,P39019,Q6UN15 17 +Absent toe 0.3331575317890116 0.9235587064622516 0.355716121636739 1.0 0.8316517045624902 26 O75175,P55011,Q12830,Q9BPU6,P02545,Q7Z6Z7,P21333,Q8N3R9 8 +Poor speech 0.2774587246597567 0.9216240225866836 0.3567247235751414 1.0 0.8316517045624902 95 Q9UQN3,P55011,P51608,P36543,Q05682,Q96N67,Q9HD42,Q15233,Q8WXI9,Q96JM3,P15311,Q6PJT7,Q6P1N0,Q9UQE7,Q8TB37,O60826,Q12904,O60610,P51610,Q9BZI7,P55072,Q14683 22 +Decreased serum complement c3 0.7191289966924018 0.920137772855538 0.3575007674719099 1.0 0.832317668558099 2 Q03252 1 +Mild global developmental delay 0.3804439903086354 0.91307522303579 0.3612029804006091 1.0 0.8350421587818341 17 Q9P0J1,Q9H2P0,P33991,Q15233 4 +Abnormality of the 2nd toe 0.4396239838660247 0.908177133321574 0.3637846433190241 1.0 0.8389614081903253 10 P51610,P51608 2 +Abnormal foramen magnum morphology 0.6210295150700935 0.9051170421722072 0.3654033845186775 1.0 0.8406086771575714 4 O75369 1 +Female reproductive system neoplasm 0.3616701324984693 0.9046978969056104 0.3656254555829477 1.0 0.8407033607590093 21 P20585 1 +Delayed ability to roll over 0.7385882556248848 0.9043405997975652 0.3658148248271504 1.0 0.8407227947437033 3 P51608 1 +Chromosomal breakage induced by ionizing radiation 0.5748410999169716 0.902943714312902 0.3665557683774865 1.0 0.8411776077284838 5 Q99496,Q92878,Q969G3 3 +Abnormal dental pulp morphology 0.4518331949944121 0.9021848599380424 0.3669586760322643 1.0 0.8412713209284323 9 P06748,Q9NPE3,Q9Y366 3 +Abnormal dental root morphology 0.4518331949944121 0.9021848599380424 0.3669586760322643 1.0 0.8412713209284323 9 P06748,Q9NPE3,Q9Y366 3 +Giant platelets 0.7141675854465592 0.8998936909653493 0.3681768279320745 1.0 0.8415729067391686 2 P35579 1 +Severe short limb dwarfism 0.7141675854465477 0.8998936909653021 0.3681768279320996 1.0 0.8415729067391686 2 O75369 1 +Abnormality of the 5th metacarpal 0.7141675854465438 0.8998936909652867 0.3681768279321078 1.0 0.8415729067391686 2 P21333 1 +Aplasia hypoplasia of the 5th metacarpal 0.7141675854465438 0.8998936909652867 0.3681768279321078 1.0 0.8415729067391686 2 P21333 1 +Palmar telangiectasia 0.7141675854465217 0.8998936909651958 0.3681768279321562 1.0 0.8415729067391686 2 Q13043 1 +Periventricular heterotopia 0.4303700196274322 0.8973670187878657 0.3695231055053931 1.0 0.8425129405347227 11 P19022,Q6ZXV5,Q9UBM7,P21333 4 +Long foot 0.4376305023019325 0.8965351470039105 0.369967017504371 1.0 0.8425848002669043 10 P21333,Q96L73,O14802 3 +Pelvic kidney 0.4507932128977473 0.8963421351210122 0.3700700618344634 1.0 0.8425848002669043 9 Q8NFV4,Q15056,Q9UIG0 3 +Abnormality of the inner ear 0.4299021936120419 0.8945633755217938 0.3710205372993282 1.0 0.8439218976162401 11 Q9P2D1,Q13428 2 +Arnold chiari type i malformation 0.4942353592529546 0.8931946997240069 0.3717529160104906 1.0 0.8443478986807185 7 O14802,Q6UX04 2 +Recurrent hand flapping 0.6172090457804731 0.8893826038785115 0.3737974909636412 1.0 0.8474754756007331 4 Q06787,O95714,Q9UNW9 3 +Thick nasal alae 0.3963654371012357 0.8889089769742702 0.3740520005281826 1.0 0.8474754756007331 14 Q96GM5,P11166,Q8TAQ2,Q969G3,O75179,Q92785,Q12824,O00443,O14497 9 +Sound sensitivity 0.4360017179183017 0.887039070302268 0.3750578658671317 1.0 0.8474754756007331 10 Q9GZY8,Q8NFV4,Q15056,Q9UIG0 4 +Autosomal dominant germline de novo mutation 0.7339173710186095 0.88683667893934 0.3751668369457772 1.0 0.8474754756007331 3 Q9HCK8 1 +Abnormality of the hallux 0.2871044476907699 0.8865552724976137 0.3753183836424163 1.0 0.8474754756007331 59 Q6UX04,O75175,Q14683,P55011,Q12830,Q8NFV4,P25490,Q15056,Q9BPU6,O60826,Q7Z6Z7,P21333,Q9H2P0,Q8N3R9,Q9UIG0,Q15233 16 +Pancytopenia 0.3116423615136353 0.8861068244183096 0.3755599659399111 1.0 0.8476091120557392 36 P06748,Q5F1R6,O60934,Q9NPE3,Q14980,P00374,Q01130,Q9Y2V7,Q6UN15 9 +Amenorrhea 0.3059424909400481 0.8853893517839065 0.3759466734470047 1.0 0.848069995877782 40 Q9P2D1,P29401,Q9UQE7,Q14683,O60885,Q969G3,Q99496,Q12830,P54098,P02545,P82650,Q15031,Q9H7N4,P51809 14 +Narrow nasal bridge 0.7328442944065118 0.8828236821789608 0.3773315429588053 1.0 0.8499562191612062 3 Q6ZRS2 1 +Large forehead 0.523020822063399 0.8818290772680824 0.3778692448504595 1.0 0.8502754378629082 6 Q06787,P21333,Q8NC56 3 +Generalized amyotrophy 0.3206471761771852 0.8809394330725743 0.3783506027849084 1.0 0.8502754378629082 28 O14802,P02545,P54098,Q9UGM6,P55072,Q9NW13,Q03252 7 +Increased circulating acth level 0.5698029370786246 0.8808054130812082 0.3784231494138139 1.0 0.8502754378629082 5 P40818 1 +Cleft upper lip 0.3127662320217461 0.8807213386111218 0.378468664304485 1.0 0.8502754378629082 35 Q9P2D1,Q13428,O60934,O75369,P39019,Q8NCM8,Q14683 7 +Hypoplastic nipples 0.4266210535356098 0.8749366285999594 0.3816083876732721 1.0 0.8540291164525938 11 Q9UQE7,P10586,Q14683 3 +Hyperactivity 0.3278224165962054 0.874807320293607 0.3816787534969381 1.0 0.8540291164525938 165 Q96ST3,P23378,Q9UBM7,O60885,P55011,P51608,O95319,O75179,Q7Z6Z7,Q92785,Q9UIG0,Q9P2D1,Q7Z3K3,O75175,P17480,O60934,Q12830,Q8NFV4,Q8WXI9,O14974,P15311,P19022,Q6PJT7,Q6P1N0,P25490,Q13409,Q9UQE7,Q9BPU6,Q15056,Q7LBC6,Q01082,Q9H2P0,Q9GZZ9,Q6ZRS2,Q96L73,Q5F1R6,Q96T60,P29401,P11166,P42345,P51610,Q9Y2W2,Q9BZI7,Q8N3R9,Q14683 45 +Astrocytosis 0.4902268784759462 0.8730022436756878 0.3826618547792768 1.0 0.8545072749444014 7 P42345,P54098,Q9UQN3 3 +Rimmed vacuoles 0.3936362854268444 0.8708076983091235 0.3838591611741422 1.0 0.8567692228512194 14 P09651,O14908,O75190,P43243,P02545,P55072,P50402 7 +Abnormality of dental morphology 0.2767247350367081 0.869365839210352 0.3846470616123567 1.0 0.8571185975025312 69 Q9UBM7,O60832,P55011,Q7Z6Z7,Q92785,Q9UIG0,O75175,Q12830,Q8NFV4,P06748,Q9UQE7,Q9NPE3,Q15056,Q9BPU6,Q6ZRS2,Q5F1R6,Q13428,Q9Y366,O60828,Q8N3R9 20 +Recurrent urinary tract infections 0.3081734799672434 0.8688340249554977 0.384937919730532 1.0 0.8571185975025312 37 Q9Y448,P78347,P11274,O14802,O60934,O43709,P20700,Q05655,Q8NFV4,Q15056,P54132,Q14697,P07741,Q9H2P0,P26038,Q9UIG0 16 +Aortic dissection 0.6119691119691105 0.8678708966644434 0.3854650128672165 1.0 0.8578811852461472 4 P01889,P31153,Q02809 3 +Lethargy 0.2699500786550342 0.8658091152632171 0.386594849638779 1.0 0.8588060847456591 91 P23378,O43772,P11166,P61254,O14678,Q8TB37,P62913,O75380,P62273,P62081,Q8N183,P62899,P62857,P39019,P40818,Q14683 16 +Fatigable weakness of respiratory muscles 0.3796708245936219 0.8651374291895424 0.3869633632800329 1.0 0.8588106941399554 15 Q9Y281,P43243,Q14203,Q9UQN3 4 +Aortic regurgitation 0.3195333578374694 0.8650861242378084 0.3869915200191665 1.0 0.8588106941399554 27 P11274,P36543,Q8NBM4,P18583,P02545,Q01082,P21333,Q6ZXV5 8 +Spina bifida occulta 0.3613410308598791 0.8641321101852816 0.387515321404293 1.0 0.8591525279416745 20 Q8NFV4,Q15056,Q9Y2W2,O75369,P21333,Q9UIG0 6 +Recurrent skin infections 0.3697128715968112 0.8623139219607507 0.3885147936923365 1.0 0.8598638311514846 18 P40818,Q9Y4L1,P78536,O14802 4 +Postaxial hand polydactyly 0.365379863683055 0.8611936359853801 0.389131404543054 1.0 0.8598638311514846 19 Q9UBM7,P21333,Q13049,Q9NQ48,Q8NCM8,O15078 6 +Abnormality of the pulmonary artery 0.3024498508436735 0.8600582741027536 0.3897569204964397 1.0 0.8604277480033042 41 O75175,O43709,P55011,Q12830,Q8NFV4,Q15056,Q9BPU6,P02545,Q7Z6Z7,Q96DF8,Q8N3R9,Q9UIG0 12 +Decreased cervical spine flexion due to contractures of posterior cervical muscles 0.5182097223967487 0.8591478176652785 0.3902589686273967 1.0 0.8608130337846613 6 P02545,Q15149 2 +Abnormality of the cheek 0.2813068043485902 0.8590699435123471 0.3903019285957136 1.0 0.8608130337846613 64 Q9P2D1,P10412,Q13428,Q04721,P18583,Q96JJ3,P17980,Q9Y2W2,Q8N201,P02545,O60826,O75369,Q9Y366,Q01082,P21333,O75845,O15078,P35573 18 +Hyperpituitarism 0.3648797252220436 0.8574488946787433 0.3911968470934699 1.0 0.8619685862699643 19 O14802,Q969G3,Q99496,P82650,P33991,Q15031,Q8IY37,Q12824,Q06787,P51809 10 +Recurrent otitis media 0.3179431732215138 0.855614353161901 0.3922111281008016 1.0 0.8631311503213289 28 Q9UBM7,O14802,Q99496,Q12830,P62913,Q92785,P21333,Q6ZRS2 8 +Impaired mastication 0.4866644567127908 0.8551151924160098 0.3924873797926735 1.0 0.8631311503213289 7 P11047 1 +Short foot 0.3116773788859285 0.8548157387834394 0.3926531637140713 1.0 0.8631311503213289 34 Q9UQE7,P51608,P18583,Q7Z6Z7,Q8NCM8,Q14683 6 +Accelerated skeletal maturation 0.4032806896231252 0.8525015843950879 0.3939357600068989 1.0 0.8643151448310005 13 Q15910,Q96L73 2 +Syringomyelia 0.5628165292435576 0.8502447848697969 0.3951890074156869 1.0 0.8666556476926368 5 Q04721 1 +Pollakisuria 0.6071339562682443 0.8480962450433768 0.3963843726485518 1.0 0.8684574161705896 4 O60934,Q06787 2 +Abnormality of the calcaneus 0.4289370365861544 0.8460309289931388 0.3975354904857315 1.0 0.8704008794238 10 P21333,O75147,Q15910,O75369 4 +Contiguous gene syndrome 0.7006615214994428 0.8452172957321947 0.3979895273051939 1.0 0.8704736866672667 2 P62263 1 +Nephrocalcinosis 0.3244645461703118 0.8451019425182348 0.3980539238579603 1.0 0.8704736866672667 26 Q5F1R6,Q8N1G0,P78347,P61011,O43709,Q6P1J9,Q8NFV4,Q15056,Q9H078,Q9UNF1,Q9Y3A5,O00443,Q9UIG0,Q6ZRS2 14 +Multicystic kidney dysplasia 0.3305695718111842 0.8399238526869025 0.4009510827422264 1.0 0.8711979146176811 25 Q9UBM7,Q9UQE7,O60885,Q13049,O15078,Q14683 6 +Delayed eruption of primary teeth 0.6987320837927172 0.8374622352506016 0.4023327959578497 1.0 0.8711979146176811 2 Q8NC56 1 +Neurofibromas 0.5128584316914632 0.8340269929413735 0.4042657732129839 1.0 0.8713466063876373 6 Q99496,Q969G3,Q01082 3 +Speech apraxia 0.3161635922054732 0.8339158443493342 0.4043284081020863 1.0 0.8713466063876373 27 P55011,Q12830,Q9BPU6,Q7Z6Z7,Q8N3R9,Q6ZRS2,Q15233 7 +Postnatal growth retardation 0.2774801237374518 0.8336543660139858 0.4044757802900913 1.0 0.8713466063876373 66 Q96ST3,Q9P2D1,Q9UQE7,P11166,P36543,P02545,O75179,O60826,Q92785,P33991,P54132,Q14315,P21333,P26373,Q14683 15 +Decreased fertility 0.3148402822510091 0.8330290499869937 0.4048283458555861 1.0 0.8713466063876373 29 Q9P2D1,O75147,P02545,P82650,Q96L73,P54132,Q9H7N4,P40818,P51809 9 +Echolalia 0.4265147061878658 0.8320426540526737 0.4053848688516737 1.0 0.8718982200638496 10 Q15149,Q9UQN3,Q01082 3 +Abnormal circulating estrogen level 0.4117039382720439 0.8319097675958156 0.4054598781058702 1.0 0.8718982200638496 12 O14802,Q99496,Q969G3,P82650,Q15031,Q8IY37,P51809 7 +Exertional dyspnea 0.3520186594620254 0.8289291270329202 0.4071445124513786 1.0 0.8740265380180826 21 P06748,Q14980,P11047,P02545,P54098,Q6UN15 6 +Semilobar holoprosencephaly 0.6022925624581076 0.8283735996266062 0.4074589530071795 1.0 0.8741744019503062 4 Q14683 1 +Metaphyseal sclerosis 0.5110687849883588 0.8256526241414259 0.4090011741171095 1.0 0.8762694587930882 6 Q5F1R6,Q14807,P61011 3 +Wrist flexion contracture 0.5103106183354731 0.8221091360363633 0.4110147862885569 1.0 0.8786354001704 6 P51608 1 +Poikilocytosis 0.3674608480574167 0.8199569058125865 0.4122406744261901 1.0 0.8799643610741872 17 Q05682,Q02241,P11166,Q9NP58 4 +Abnormal foveal morphology 0.599896475412787 0.8186428018940388 0.4129902392326103 1.0 0.8807552279549979 4 P35221,P26367 2 +Abnormal hand bone ossification 0.5092899461047371 0.8173428137436134 0.4137325462558863 1.0 0.881673642933526 6 O75369 1 +Phimosis 0.598821673450126 0.8142846523613156 0.4154818998998935 1.0 0.8834020032928865 4 O60828,Q96L73 2 +Prominent digit pad 0.3394626076769484 0.8128117174220806 0.4163260164172624 1.0 0.8838131559118403 23 Q15910,O75175,P55011,Q12830,Q9BPU6,Q7Z6Z7,Q8N3R9 7 +Abnormal venous morphology 0.3116639401132667 0.8106977792397001 0.4175392489876384 1.0 0.885042598887738 30 Q6UX04,Q71SY5,Q8NC56,O14802,Q99496,P36543,Q13043,P98175,P02545,Q7LBC6,Q6ZRS2,Q02809 12 +Neuroinflammation 0.5535844906323528 0.8101358900579468 0.4178620788894904 1.0 0.885042598887738 5 Q8NBM4 1 +Abnormality of urine calcium concentration 0.3842068811410528 0.8087595274456938 0.4186534803177391 1.0 0.885042598887738 14 P78347,O43709,Q6P1J9,Q8NFV4,Q15056,Q9UNF1,O00443,Q9UIG0 8 +Ulnar deviation of finger 0.4469998355811896 0.8083166657529932 0.418908310974369 1.0 0.885042598887738 8 Q15042,Q9UBM7 2 +Abnormal urine alpha ketoglutarate concentration 0.5069387386223758 0.8063812587022189 0.4200230497395263 1.0 0.885042598887738 6 P09622,P30038 2 +Focal non motor seizure 0.4218859819052195 0.8054258135154341 0.4205740006840566 1.0 0.885042598887738 10 Q96JM3 1 +Leukopenia 0.286721596757742 0.8051827211088874 0.4207142459528756 1.0 0.885042598887738 48 P06748,Q5F1R6,P61254,O60832,Q14980,P62913,P62273,P62081,P62857,P46777,P62899,P39019,P61353,Q6UN15 14 +Premature graying of hair 0.4343113404183554 0.8045522306149644 0.4210781174927509 1.0 0.885407245243807 9 P06748,Q9NPE3,P02545 3 +Ventricular tachycardia 0.3834784339498202 0.8040009254092529 0.4213964405607202 1.0 0.8856758296181216 14 O43772 1 +Focal onset seizure 0.2648905244444925 0.8034209241709561 0.4217314850261395 1.0 0.8857234790144637 90 P46821,Q9Y3C6,Q96C36,Q9BVA1,P55011,P54098,Q96N67,Q6ZXV5,Q7Z3K3,Q71SY5,Q969G3,P15311,Q96JM3,P19022,Q6PJT7,Q6P1N0,Q96N66,Q99496,Q9BPU6,Q9UGM6,Q01082,O94979,Q12904,Q96T60,Q96L73,P11166,O14802,P42345,P67870,P21333,Q14683 31 +Inspiratory stridor 0.690187431091504 0.8033018066504513 0.4218003139786976 1.0 0.8857234790144637 2 Q14807 1 +Tracheomalacia 0.4214428083079026 0.8028855366495523 0.4220408964657909 1.0 0.885828385671423 10 O75369,P46777 2 +Limitation of knee mobility 0.4337350546522363 0.8013735839249749 0.4229154031930173 1.0 0.8865801481346265 9 P21333,Q14315,Q15910,Q9BPU6 4 +Aplasia hypoplasia involving bones of the upper limbs 0.3150817052103651 0.8001969702288956 0.4235966849355392 1.0 0.8865947507033308 152 Q96ST3,Q9UBM7,O60885,P51608,Q96AY3,P53597,P62913,P18583,Q7Z6Z7,Q92785,Q32P28,Q03252,Q6UX04,Q9P2D1,O75147,O75175,Q9Y448,Q969G3,Q04721,Q12830,Q9NR45,P98175,P11274,Q9UQE7,P61254,Q99496,P62273,Q14807,P62081,O60826,P62899,O75369,P62857,P39019,P02545,P46777,Q9H2P0,P61353,Q6ZRS2,Q96T60,O14802,P42345,P51610,Q9Y366,Q9BZI7,P82673,P21333,Q8NCM8,Q14683 49 +Abnormal large intestine morphology 0.2596395717493143 0.799896619454086 0.4237706965853687 1.0 0.8865947507033308 85 P62913,Q15437,P20585,Q9UIG0,O43709,Q8NFV4,Q13043,Q9Y2V7,P61254,Q15056,P62273,P02545,P62081,O75369,P62899,P54132,P62857,P39019,P46777,Q13428 20 +Abnormality of the sense of smell 0.3482424445083124 0.7996176991528349 0.4239323296885735 1.0 0.8865947507033308 21 O15078 1 +Abnormal facial expression 0.2977585346614848 0.799091306348884 0.4242374702544804 1.0 0.886647324883755 40 Q9Y448,Q14203,P51608,Q14331,Q8WXI9,Q13049,Q6P1N0,Q9GZZ9 8 +Abnormal bronchus physiology 0.5052635382714472 0.7985871031564 0.4245298682733709 1.0 0.886647324883755 6 Q9UER7,Q9H0U9 2 +Bronchospasm 0.5052635382714472 0.7985871031564 0.4245298682733709 1.0 0.886647324883755 6 Q9UER7,Q9H0U9 2 +Abnormality of the pulmonary vasculature 0.2893199064818181 0.7941163705504081 0.4271276881582075 1.0 0.8897787349817496 46 O75175,O43709,P55011,Q12830,Q8NFV4,Q15056,Q9BPU6,P02545,Q7Z6Z7,Q96DF8,Q8N3R9,Q9UIG0,Q14683 13 +Secundum atrial septal defect 0.7086906359259699 0.7934166926647823 0.42753508838163 1.0 0.8897787349817496 3 P62913 1 +Polyuria 0.549595764317104 0.7929133375230183 0.4278283160232057 1.0 0.8897787349817496 5 Q9NQ48,P18583 2 +Cerebellar malformation 0.2657179015927012 0.790918584837035 0.4289915025170021 1.0 0.8902351796175763 73 Q6UX04,Q9P2D1,Q9UBM7,O14802,O43709,P36543,P18583,Q8NFV4,O14974,Q15056,Q9BPU6,O60826,Q92785,P21333,Q8NCM8,Q9UIG0,O15078,Q15233 18 +Knee clonus 0.6868798235942912 0.7901628370193485 0.4294326763940039 1.0 0.8902351796175763 2 O75298 1 +Cleft soft palate 0.2775289151091052 0.7891465915692784 0.4300263332868055 1.0 0.8902767025139308 62 Q13428,P61254,O14802,P18583,P62273,P62913,P62081,P62899,P46777,P62857,P39019,P21333,Q14683 13 +Coxa vara 0.3658874858784936 0.7878158586205103 0.4308044234877692 1.0 0.8902767025139308 16 Q5F1R6,Q96AY3,P26373 3 +Synostosis of joints 0.2981025495752186 0.7847105098749956 0.432623319304688 1.0 0.8902767025139308 38 Q9UQE7,Q14683,O60885,P61254,Q8NFV4,Q15056,Q9Y2W2,O75369,O60828,P21333,Q9UIG0,Q15233 12 +White hair 0.5475805962774962 0.7842384577792815 0.4329002030947415 1.0 0.8902767025139308 5 P06748,Q9NPE3 2 +Oral leukoplakia 0.5475805962774962 0.7842384577792815 0.4329002030947415 1.0 0.8902767025139308 5 P06748,Q9NPE3 2 +Acute lymphoblastic leukemia 0.362178909056832 0.7826053820958985 0.4338588799809089 1.0 0.8917037661527127 17 P11274,O60934,P54132,P35658,O00165,Q96L73 6 +Aplastic hypoplastic toenail 0.2950146819123908 0.7812459312955313 0.4346578639046139 1.0 0.8929509697456857 41 P06748,Q96GM5,Q15910,P11274,P78347,O43709,O60832,Q969G3,Q9NPE3,Q8TAQ2,Q8NFV4,Q14739,Q15056,Q92785,Q12824,O14497,Q9UIG0,Q96L73 18 +Ankle flexion contracture 0.379878393851724 0.7805638109299775 0.4350590833657701 1.0 0.8932133676894103 14 P21333,Q96AY3,Q96L73,Q5JTV8 4 +Acne 0.3647618754264395 0.7800486685358204 0.4353622289254388 1.0 0.8932133676894103 16 Q9Y4L1,P40818 2 +Vascular dilatation 0.2618363417104039 0.778846105483441 0.4360703746825742 1.0 0.8935648077597073 75 P46821,P55011,Q7Z6Z7,Q6ZXV5,Q9UIG0,Q02809,Q9P2D1,O75175,O43709,Q12830,Q8NFV4,Q8TDP1,P11274,Q15056,Q9BPU6,P02545,O75369,Q01082,Q96L73,P14314,P21333,Q8N3R9 22 +Small epiphyses 0.7046848190263537 0.7787781850568 0.4361103903591599 1.0 0.8935648077597073 3 Q14807 1 +Impaired t cell function 0.4025580529681062 0.7765352118817174 0.4374330384947147 1.0 0.8940375564675147 12 Q96DF8 1 +Abnormal granulocytopoietic cell morphology 0.5891553342867292 0.7752879103850285 0.4381695515341053 1.0 0.8940375564675147 4 Q14980 1 +Joint hyperflexibility 0.287323327297259 0.7719303889479766 0.4401556575280223 1.0 0.8949807114037764 46 O75147,Q15910,O43709,Q04721,Q8NFV4,Q15056,Q9Y366,Q9BZI7,P02545,O75369,P21333,Q9UIG0,Q96L73 13 +Bone pain 0.3394822835810966 0.7699783708160213 0.4413127229971847 1.0 0.8949807114037764 22 P06748,Q8N1G0,Q14980,Q01130,P55072,O75874,P48735,Q6UN15 8 +Large face 0.2595940661889884 0.7697057840912596 0.4414744382440918 1.0 0.8949807114037764 76 Q96ST3,P55011,Q12830,Q9BPU6,Q96JM3,O14974,Q9BZI7,Q7Z6Z7,O75369,Q96L73,O60828,P21333,Q8N3R9,O15078,Q15233 15 +Reduced circulating prolactin concentration 0.5440231792141792 0.7689693750649358 0.4419114911216737 1.0 0.8949807114037764 5 Q99496,Q969G3,Q9NW13 3 +Ischemic stroke 0.7019575406672156 0.7688460994341497 0.4419846784167882 1.0 0.8949807114037764 3 P31153,P18583 2 +Slowly progressive 0.2780771871127804 0.7671703849438825 0.4429802182978026 1.0 0.8949807114037764 58 Q9Y281,Q14203,O75190,P51608,Q14331,Q14315,Q9BRK0,Q13049 8 +Breast hypoplasia 0.5432772843949463 0.7657753271524607 0.4438099973102813 1.0 0.8949807114037764 5 Q9P2D1 1 +Gonadoblastoma 0.7008547008546986 0.7648379093550833 0.4443680707652335 1.0 0.8949807114037764 3 Q8IY37,P51809 2 +Abnormality of the calf musculature 0.352323521168784 0.7644679672219709 0.4445884187803508 1.0 0.8949807114037764 19 P43243,Q14331,P02545,Q14315,Q13049 5 +Reduced subcutaneous adipose tissue 0.4265006809249575 0.7616745739031897 0.4462542541642238 1.0 0.8958007741779391 9 P36543,Q9NW13,O14802 3 +Recurrent bronchitis 0.5421426176900953 0.7609215762282661 0.4467039104124044 1.0 0.8958007741779391 5 O60934,O15533 2 +Skin ulcer 0.3020629878474743 0.760693507265144 0.4468401537646789 1.0 0.8958007741779391 34 P06748,O60832,Q9NPE3,P02545,Q14692,O75874,P48735,Q15149 8 +Abnormal thalamic mri signal intensity 0.4261871565044817 0.7599630359209302 0.4472766802720298 1.0 0.8959029022517769 9 Q99496,P54098,Q9GZY8 3 +Bladder diverticulum 0.4257555057693271 0.7576079136713835 0.4486857412193161 1.0 0.8970244374548316 9 O43709,Q8NFV4,Q15056,Q9UIG0 4 +Cupped ear 0.3762166691020964 0.7568693070539457 0.4491281653275658 1.0 0.8972908788809967 14 Q5F1R6,Q96ST3,Q9P2D1,Q7Z6Z7,O60828 5 +Abnormal cranial nerve morphology 0.2706207559187589 0.7561916006931335 0.4495343279280919 1.0 0.8973307654131628 67 Q9Y281,Q9P2D1,Q14203,Q99496,P51608,Q14331,O75190,P11047,P51610,Q9BZI7,P54098,Q14692,Q13049,Q15149 14 +Impaired pain sensation 0.3422000284388737 0.7531669928954703 0.4513495711987962 1.0 0.8982109270818731 21 P17480,P51608,Q14683,Q96JM3 4 +Prominent nose 0.3313341734724778 0.7470278277386367 0.455046763385218 1.0 0.9033664051331108 23 Q13409,O60934,Q12830,Q6ZRS2,Q15233 5 +Abnormal stomach morphology 0.252018950085205 0.7466249575467477 0.4552899789674109 1.0 0.9033664051331108 81 P46821,Q9UBM7,O60885,P51608,P20585,Q6ZXV5,Q9UIG0,O43709,Q8NFV4,P50454,Q9NYB0,P11274,Q9UQE7,Q99496,Q15056,P54132,Q15149,P51610,Q9BZI7,P21333,Q14683 21 +Hypodontia 0.2774135114491068 0.7427428638984495 0.4576373732859871 1.0 0.9034371283790898 52 P06748,Q9GZZ9,Q5F1R6,Q8NC56,O14802,O43709,O60832,Q9NPE3,Q8NFV4,O95319,Q15056,Q9Y366,P02545,O75369,Q9NW13,Q9UIG0,Q96L73 17 +Abnormal cartilage morphology 0.3739854186732443 0.7425068762169573 0.4577802871935719 1.0 0.9034371283790898 14 O75874,Q13428,P48735 3 +Neoplasm of the liver 0.2912501848188318 0.7419754116745448 0.4581022333023337 1.0 0.9034371283790898 41 P42771,Q96GM5,Q9NWH9,Q13263,Q9UDY2,Q8TAQ2,Q969G3,P54277,O14497,Q13043,P08397,Q92785,P50336,Q8WX93,Q12824,Q15477,Q05655 17 +Anorexia 0.3034219084679679 0.7417358714950673 0.4582473814482157 1.0 0.9034371283790898 31 Q9UER7,Q14980,P51608,Q8NBM4 4 +Pes planus 0.25680043473379 0.7415983795652786 0.4583307056302348 1.0 0.9034371283790898 86 P51608,P36543,Q9UIG0,Q6UX04,Q15233,Q9P2D1,O75175,O43709,Q12830,Q8NFV4,Q15056,P02545,Q9HCK8,O75369,Q7L2E3,Q96L73,P42345,P51610,Q9BZI7,P21333 20 +Cutaneous melanoma 0.5375769963407084 0.7414550290479752 0.4584175893370648 1.0 0.9034371283790898 5 Q99496,P11802 2 +Hypoplasia of penis 0.2869532755444242 0.7405848050827195 0.4589452239294425 1.0 0.9034371283790898 119 Q96ST3,Q9UBM7,O43837,O60885,Q7Z6Z7,Q9H7N4,Q13049,Q9NQ48,Q03252,Q9UIG0,O15078,Q9P2D1,Q8NFV4,O14974,P19022,Q8TDP1,Q15910,Q9UQE7,Q9BPU6,Q15056,O60826,Q01082,Q15042,Q96T60,Q96L73,Q13428,O43395,Q8NCM8,Q14683 29 +Generalized hypopigmentation of hair 0.4341588531898582 0.740479573541609 0.4590090510228171 1.0 0.9034371283790898 8 P06748,Q9NPE3,O60832 3 +Pallor 0.2789639338593894 0.7385281183035327 0.4601935868331122 1.0 0.9050019458372712 49 P11166,P61254,P00374,P62273,P62913,P62081,P62857,P62899,P39019 9 +Aplasia hypoplasia involving bones of the lower limbs 0.273733681070223 0.7369855194057242 0.4611311554150958 1.0 0.906462131647187 104 Q9UBM7,Q9NWH9,O60885,P55011,P51608,Q96AY3,P53597,P18583,Q7Z6Z7,Q9NQ48,Q9P2D1,Q9Y448,O75175,Q04721,Q12830,Q15910,Q9UQE7,Q99496,Q9BPU6,P02545,O75369,O14802,Q9Y366,P21333,Q8NCM8,Q8N3R9,Q14683 27 +Coronal cleft vertebrae 0.6928591122139486 0.7359232935010055 0.4617773805666885 1.0 0.9073486205046096 3 O75369,P36776 2 +Sparse eyelashes 0.3481457014620389 0.7340282236785486 0.4629315368416629 1.0 0.907950006580775 19 Q13428,O14802,Q9NPE3,O60832,P02545,P54132,Q6UX04 7 +Abnormal aortic valve cusp morphology 0.3050012555218026 0.7323083511349332 0.463980383255856 1.0 0.907950006580775 27 Q9UQE7,P61254,Q8NFV4,Q15056,Q01082,P21333,Q9UIG0 7 +Increased endomysial connective tissue 0.6719955898566633 0.7316775924917241 0.4643653762260027 1.0 0.907950006580775 2 Q5JTV8 1 +Hyperphenylalaninemia 0.6717199558985831 0.7306050416834021 0.4650204316413739 1.0 0.9087031263519648 2 P09417 1 +Infectious encephalitis 0.4019142849992223 0.7296642004178706 0.4655954688711057 1.0 0.9087031263519648 11 Q9Y4L1 1 +Tip toe gait 0.6908629539032006 0.7287456802987687 0.4661572444908746 1.0 0.9090359694289109 3 Q9ULH0 1 +Generalized osteoporosis 0.5765203107030783 0.724908560392902 0.4685081288660067 1.0 0.9117214573730044 4 P02545,Q6P1J9 2 +Short thorax 0.4311148333340603 0.7245770417761298 0.4687115475928787 1.0 0.9117214573730044 8 Q8NCM8,P11166,Q9Y366 3 +Urinary bladder sphincter dysfunction 0.4068437039441158 0.7200972135870481 0.4714651430026593 1.0 0.9121142878989832 10 P09651,O75298,P10809,P55072,Q9BRK0,Q06787 6 +Widely patent fontanelles and sutures 0.5748932328596851 0.7184746531404609 0.4724646710056481 1.0 0.9132875732792208 4 P98175,O14802 2 +Round face 0.3162276735145546 0.717309054241566 0.473183421710903 1.0 0.9139166087658214 25 Q15910,Q14683,Q9UHD8,P52815,P02545,P82673,P40818,Q96L73 8 +Abnormality of circulating adrenocorticotropin level 0.3994566819230106 0.7155062431757612 0.4742962844859248 1.0 0.914542391083051 11 Q9UER7,P40818 2 +Prominent occiput 0.3552737697366667 0.7152403702001693 0.4744605276144971 1.0 0.914542391083051 16 O75175,Q9Y366,O60826,O75369,P21333 5 +Short 1st metacarpal 0.4583192150609267 0.7152039045846404 0.474483056697911 1.0 0.914542391083051 7 Q9UQE7,Q14683 2 +Bowel diverticulosis 0.4059149989106527 0.7148949962012053 0.4746739291712805 1.0 0.914542391083051 10 Q8NFV4,Q15056,Q9UIG0 3 +Abnormal pancreas size 0.4292499975789818 0.7148718396659223 0.4746882391418805 1.0 0.914542391083051 8 Q5F1R6,P61011,Q7Z2Z2 3 +Proximal femoral metaphyseal irregularity 0.684587813620069 0.7062947678746923 0.4800048465049105 1.0 0.9205870910888648 3 Q5F1R6,P61011 2 +Small for gestational age 0.2542431317942095 0.7034902796527948 0.4817502623216905 1.0 0.9221576684925736 86 Q96ST3,P55084,P51608,P62913,Q7Z6Z7,O75147,P36776,P50570,Q15477,O00443,P61011,P25490,P61254,P62273,Q9Y584,Q14807,P62081,P62899,P54132,P62857,P39019,P46777,P61353,Q6ZRS2,Q5F1R6,P47985,P18074,P38935,P51610,Q9BZI7,O60828,Q9Y3A5,P62847 33 +Apraxia 0.264418051429277 0.7027479263754952 0.4822128544086408 1.0 0.9221576684925736 69 Q6ZRS2,O75175,Q96T60,Q9UQN3,P11166,Q14683,P55011,P51608,Q12830,Q9BPU6,Q7Z6Z7,P18887,P55072,Q8N3R9,O15078,Q15233 16 +Facial cleft 0.5278636582040596 0.7004027780843791 0.4836758018272802 1.0 0.9224073353420538 5 Q13428 1 +Transient global amnesia 0.5277017408509478 0.6997228901481815 0.4841003785119835 1.0 0.9224073353420538 5 Q99496,Q969G3,P25490 3 +Pulmonary artery dilatation 0.3528559901098728 0.6989318179345411 0.4845946418844127 1.0 0.9224073353420538 16 P55011,Q12830,Q9BPU6,Q7Z6Z7,Q8N3R9 5 +Dicarboxylic aciduria 0.3007542370444306 0.6981745560231927 0.4850680366013216 1.0 0.9224073353420538 28 O43772,O14678,P51610,P54098,P48735 5 +Quadriceps muscle weakness 0.4547635252160907 0.6980164831051476 0.4851668858948597 1.0 0.9224073353420538 7 Q13049,P54098 2 +Autoimmunity 0.2879174739302534 0.6979351612920713 0.4852177439137548 1.0 0.9224073353420538 40 Q9P2D1,Q92888,O60934,P22314,Q9UJV9,Q13043,P54098,Q15437,Q8TDP1,O00192,Q9UBC1,P61011,Q05655,Q06787,Q03252 15 +Lack of peer relationships 0.6820537069742258 0.6972784757100134 0.4856285356408523 1.0 0.9224073353420538 3 P51608 1 +Thoracic aortic aneurysm 0.2886457272277899 0.6968803105287926 0.485877700746391 1.0 0.9224073353420538 39 Q9P2D1,O75175,P55011,Q12830,Q8NFV4,Q15056,Q9BPU6,P02545,Q7Z6Z7,Q8N3R9,Q9UIG0 11 +Pyelonephritis 0.662899669239243 0.6965014986319473 0.4861148190774025 1.0 0.9224073353420538 2 Q14697 1 +Reduced sperm motility 0.662899669239243 0.6965014986319473 0.4861148190774025 1.0 0.9224073353420538 2 Q14697 1 +Abnormal glomerular filtration rate 0.662899669239243 0.6965014986319473 0.4861148190774025 1.0 0.9224073353420538 2 Q14697 1 +Abnormal qt interval 0.414221714184675 0.6952613242121105 0.4868915472560946 1.0 0.9227267928142938 9 P51608 1 +Overlapping fingers 0.4021405406688416 0.6938398202866263 0.4877826672107623 1.0 0.9227267928142938 10 Q8TD16,Q2VPK5,Q71SY5,P21333 4 +Wide nasal bridge 0.3166998472310448 0.6928736539460971 0.4883888447179081 1.0 0.9227267928142938 167 Q96ST3,Q9UBM7,O43837,P55011,P51608,P18583,P62913,Q7Z6Z7,O15160,Q9UIG0,Q9Y4L1,Q9Y448,O75175,O43709,Q04721,Q8NFV4,Q8WXI9,Q12830,P98175,Q96KP1,P61254,Q9BPU6,Q15056,P62273,O95721,Q9UGM6,P62081,O60826,P62899,O75369,Q01082,P62857,P39019,P02545,Q15042,P61353,Q9H2P0,P46777,Q13428,P11166,O43395,Q8N201,Q9Y366,O60828,P21333,O94992,Q8N3R9,O75845 48 +Abnormality of chromosome stability 0.3517498959645326 0.6915011118192047 0.4892506822597986 1.0 0.923455694744632 16 Q9NRZ9,O60934,Q99496,Q969G3,P33991,P54132,Q92878,Q06787 8 +Overweight 0.4245719484755948 0.6906557828499845 0.4897818828907236 1.0 0.9237079585199648 8 Q9HCK8 1 +Incisor macrodontia 0.3454203672593364 0.6881997012978376 0.4913270320126073 1.0 0.9243628186120408 18 P55011,Q12830,Q9BPU6,Q7Z6Z7,Q8N3R9 5 +Abnormal incisor morphology 0.3454203672593364 0.6881997012978376 0.4913270320126073 1.0 0.9243628186120408 18 P55011,Q12830,Q9BPU6,Q7Z6Z7,Q8N3R9 5 +Abnormality of metacarpophalangeal joint 0.4811396455228257 0.6880237131774052 0.4914378485791948 1.0 0.9243628186120408 6 O60828,P21333 2 +Abnormal synaptic transmission at the neuromuscular junction 0.2983936432247085 0.6878908411665049 0.4915215245944377 1.0 0.9243628186120408 30 Q9Y281,Q14203,Q9UQN3,P43243,P11047,Q14315,Q15149 7 +Rheumatoid factor positive 0.5245473443851544 0.6865082063013475 0.4923926912466538 1.0 0.924710534740376 5 Q9UBC1 1 +Positive romberg sign 0.3943225063527618 0.6861329788427342 0.4926292562592254 1.0 0.924710534740376 11 Q9Y448,P18887,O14802 3 +Abnormal glial cell morphology 0.2692641954048687 0.6854316205693274 0.4930715962519538 1.0 0.924710534740376 62 Q9UQN3,O60934,P20585,O75874,P48735,Q96L73 6 +Lipodystrophy 0.2898555675328967 0.6850611773946509 0.4933053170866297 1.0 0.924710534740376 37 O14802,P36543,P02545,Q9NW13,P21333,Q03252,Q9UN37,P40818,P18206 9 +Ureteropelvic junction obstruction 0.5240554559045423 0.6844528624986911 0.4936892451576002 1.0 0.924710534740376 5 Q9UBM7,Q96L73 2 +Xerostomia 0.3528452509253862 0.6841979600609394 0.4938501702330118 1.0 0.924710534740376 15 P43243,P55011,Q14203,Q9UQN3 4 +Delayed ability to sit 0.3523941399078969 0.6812372192397226 0.4957214008777422 1.0 0.924710534740376 15 P51608,P18583,Q9BPU6 3 +Macular thickening 0.4795805739514525 0.6810007305388323 0.4958710281795428 1.0 0.924710534740376 6 P50213,P36405,Q8WWY3,P04439,Q6P2Q9 5 +Fasting hyperinsulinemia 0.5652844199916152 0.6807520941064845 0.4960283673851438 1.0 0.924710534740376 4 P02545 1 +Stage 5 chronic kidney disease 0.2968069091291893 0.6806568761969275 0.4960886291245798 1.0 0.924710534740376 31 Q15051,Q9Y5K6,P11047,O15078 4 +Abnormality of vitamin b12 metabolism 0.3756045153239054 0.6805232625542817 0.496173197433484 1.0 0.924710534740376 13 P11586,O14678,P51610,P53597,Q05655 5 +Myeloproliferative disorder 0.6772518623596174 0.680276055424397 0.4963296829353343 1.0 0.924710534740376 3 Q01130 1 +Schwannoma 0.6771836029489318 0.6800351571457236 0.4964822001672559 1.0 0.924710534740376 3 Q12824 1 +Methylmalonic aciduria 0.4112707993967979 0.6795051077688966 0.496817872367953 1.0 0.9248477332629218 9 O14678,P51610 2 +Morphological abnormality of the middle ear 0.5228184092216239 0.6792903595241632 0.496953903584574 1.0 0.9248477332629218 5 Q96L73 1 +Large hands 0.3520302129373607 0.6788510119244883 0.4972322679836742 1.0 0.9249246827934672 15 Q96L73,O14802 2 +Esophageal stenosis 0.4506563812345953 0.6782828630325919 0.4975923621656268 1.0 0.9249246827934672 7 P06748,Q9NPE3 2 +Decreased facial expression 0.2933685781790451 0.6777489671790183 0.4979308731830318 1.0 0.924975790567489 34 Q9Y448,Q14203,Q14331,Q13049,Q6P1N0,Q9GZZ9 6 +Corticospinal tract hypoplasia 0.6573869900771699 0.675411711045717 0.4994142271163375 1.0 0.9250543264379726 2 Q13045 1 +Abnormality of the chin 0.2562769529268274 0.6749121574587721 0.499731575983628 1.0 0.9250543264379726 90 P55011,P36543,Q9UIG0,Q9P2D1,Q7Z3K3,O75147,O75175,Q9Y448,O43709,Q04721,Q8NFV4,Q96JM3,P19022,P25490,Q15910,P11047,Q15056,P02545,Q9HCK8,Q7LBC6,Q01082,Q96L73,O14802,P42345,Q9BZI7,O60828,P21333 27 +Abnormal proportion of cd4 positive t cells 0.3986477160831853 0.6744866940580933 0.5000019423401132 1.0 0.9250543264379726 10 Q9Y448,P54132 2 +Mesomelia 0.4776540384349363 0.6723456128168002 0.5013636980624803 1.0 0.9250543264379726 6 P21333 1 +Abnormal anatomic location of the heart 0.3627680254053756 0.6712646417368813 0.5020519552728322 1.0 0.9250543264379726 14 P19022,P02545,O15078,O60828,Q6ZRS2 5 +Abnormal bronchus morphology 0.3162989290705451 0.6702510287327754 0.502697779288815 1.0 0.9251630021208408 24 O60934,Q92888,P54132,O75369 4 +Intellectual disability moderate 0.2499288562179142 0.6697206685114662 0.5030358734907989 1.0 0.925418726885092 84 Q96SN8,Q96GM5,P55011,P51608,P38159,Q92785,Q6UX04,Q71SY5,Q969G3,P15311,Q96JM3,Q13620,Q6PJT7,Q6P1N0,P25490,Q96N66,Q9UGM6,Q12904,Q6ZRS2,Q96L73,O14802,Q8TAQ2,P51610,Q9H269,Q9BZI7,P67870,Q06787 27 +Noncompaction cardiomyopathy 0.673701157132088 0.6677753781828049 0.5042769855951128 1.0 0.9261530047636792 3 Q15233 1 +Broad based gait 0.3261003513422192 0.6663886043290846 0.5051627444770719 1.0 0.9261530047636792 22 P46821,P51608,Q05682,P98175,Q13620,P55072,Q01082,Q6ZRS2 8 +Intellectual disability profound 0.2707983964068333 0.6663050106218387 0.505216163550279 1.0 0.9261530047636792 52 P17480,P51610,P36543,P51608,Q96JM3,Q9BZI7,Q9UGM6,Q8TDP1,Q13813 9 +Aplasia hypoplasia of the breasts 0.4086058185036058 0.6653500505120283 0.5058266249387169 1.0 0.9261530047636792 9 P02545,Q9P2D1,P25490 3 +Abnormal urine phosphate concentration 0.6724565756823794 0.6634085228828112 0.5070689488433273 1.0 0.9261920206310836 3 Q6P1J9,O14745 2 +Hyperphosphaturia 0.6724565756823794 0.6634085228828112 0.5070689488433273 1.0 0.9261920206310836 3 Q6P1J9,O14745 2 +Renal hypoplasia 0.2859099065014244 0.6628507769342954 0.5074261295172242 1.0 0.9261920206310836 38 Q9P2D1,Q9UBM7,O43709,Q8NFV4,Q15056,P39019,O60828,Q8NCM8,Q9UIG0 9 +Branchial fistula 0.4752784078057766 0.6617090028397467 0.508157733854957 1.0 0.9271334861499744 6 Q13428,P11274 2 +Enamel hypoplasia 0.3826378997718196 0.658776039719748 0.510039595582565 1.0 0.9293132818205836 12 Q5F1R6,P18074,P36776,Q9Y2V7,O75369,O00443,Q15149 7 +Ventricular fibrillation 0.5592939878654121 0.6574865200681245 0.5108681357205134 1.0 0.9293132818205836 4 P46976,Q9NX14,P49748 3 +Abnormal electroretinogram 0.2846196285090688 0.6569030239288316 0.5112432737325516 1.0 0.9293132818205836 39 Q13049,O43395,Q15051,O15078 4 +Irregular vertebral endplates 0.517110547294566 0.6555933705617198 0.5120857921600557 1.0 0.9293132818205836 5 Q14807,O14802 2 +Macular hypoplasia 0.6521499448732007 0.6555465876020461 0.5121159016883308 1.0 0.9293132818205836 2 P26367 1 +Macrodontia 0.3245093304700049 0.6543192630480984 0.512906137947551 1.0 0.9293132818205836 22 P55011,Q12830,Q9BPU6,Q7Z6Z7,O60828,Q8N3R9 6 +Lymphocytosis 0.6697939006521566 0.6540924489931697 0.5130522460149578 1.0 0.9293132818205836 3 Q03252 1 +Abnormality of vitamin d metabolism 0.3884286151019376 0.6527789215481256 0.5138988144239731 1.0 0.9296339536100396 11 Q5F1R6,Q01968,Q7Z2Z2,P62913,Q13043,Q9Y3A5,P61011 7 +Paraplegia 0.2665958639679503 0.6527315847931165 0.5139293365233897 1.0 0.9296339536100396 62 Q9P2D1,P51608,Q8N183,Q9BRK0,P07942 5 +Anemia of inadequate production 0.2582049196309229 0.6516102646350558 0.5146526242769964 1.0 0.9302181038565548 71 Q5F1R6,Q9UER7,P61254,P00374,P62913,P62273,Q15437,P62081,P62857,P62899,P39019,Q9Y4L1 12 +Receptive language delay 0.3395455271015644 0.6474873353790512 0.5173165884694484 1.0 0.9335806549970976 18 P55011,Q12830,Q9BPU6,Q7Z6Z7,Q8N3R9 5 +Methylmalonic acidemia 0.4156280072499643 0.6449155635152024 0.5189819053646203 1.0 0.9341533334605504 8 O14678,P51610 2 +Hypoplastic toenails 0.2935370362738438 0.6441788496773497 0.5194594643206614 1.0 0.9341533334605504 30 Q96GM5,Q15910,P78347,O43709,Q8TAQ2,Q969G3,Q8NFV4,Q15056,Q92785,Q12824,O14497,Q9UIG0,Q96L73 13 +Cutaneous syndactyly 0.404521672622041 0.6438008182886806 0.5197046030816779 1.0 0.9341533334605504 9 P98175 1 +Thick lower lip vermilion 0.270506128607807 0.6437550988855757 0.5197342543944687 1.0 0.9341533334605504 49 Q96ST3,Q96GM5,P51608,P38159,Q7Z6Z7,Q92785,Q12824,Q9UIG0,O43709,Q969G3,Q8NFV4,Q9NR45,Q13620,O14497,P25490,Q15056,Q9H2P0,P11166,Q8TAQ2,P51610,Q9BZI7 21 +Hashimoto thyroiditis 0.6667834554848548 0.6436038817785014 0.5198323324457212 1.0 0.9341533334605504 3 Q15437 1 +Horizontal eyebrow 0.4709278721114882 0.6423371596161503 0.5206542917875714 1.0 0.9348842712275286 6 Q8N201 1 +Sparse hair 0.2509210650412269 0.6402507376671138 0.5220096017585409 1.0 0.9354170987717744 87 Q96GM5,O60832,P36543,Q92785,Q9H7N4,Q12824,Q8IY37,Q6UX04,Q9P2D1,Q71SY5,Q969G3,Q8WXI9,Q15477,O14497,P62304,P46778,P51809,P06748,Q15910,Q9NPE3,P02545,P54132,Q9H2P0,P38646,Q96L73,Q5F1R6,P18074,Q13428,O14802,Q8TAQ2,Q14696,Q15436,Q9Y366,P82650,O60828,P21333,Q06787 37 +11 pairs of ribs 0.3921650854217553 0.6389256106954051 0.5228713262890177 1.0 0.9354170987717744 10 P39019,O75369 2 +Abnormal heart valve physiology 0.2585265221839253 0.6374938444877029 0.5238032182068304 1.0 0.9354170987717744 95 P46821,P55084,P36543,P18583,P54098,Q6ZXV5,Q9UIG0,Q15233,Q9UER7,Q9P2D1,O43709,Q04721,Q8NFV4,Q8NBM4,Q12830,P19022,Q9BU61,O95169,P11274,Q9UQE7,Q99496,Q15056,O60826,P02545,P46777,Q01082,P39019,P61353,O14802,Q14315,P21333 31 +Low hanging columella 0.3917794888196991 0.6368258172257496 0.5242383075059236 1.0 0.9354170987717744 10 Q7LBC6,Q6ZRS2 2 +Decreased adipose tissue 0.3454269468502349 0.635930903319043 0.5248214592528542 1.0 0.9354170987717744 15 O14802,P36543,P02545,Q9NW13,Q03252 5 +Abnormal labia morphology 0.3343842458889938 0.6359104465023342 0.5248347933874362 1.0 0.9354170987717744 19 Q9P2D1,Q9UQE7,Q14683,O60885,P02545,Q15042,P51809 7 +Multiple joint contractures 0.3119871636721001 0.6358586716326828 0.5248685419879682 1.0 0.9354170987717744 24 P02545,Q8TDP1,P22314,P21333,Q9NW13,Q92917 6 +Prominent supraorbital ridges 0.3784703786537737 0.6347334537419991 0.5256022712067085 1.0 0.9358230103103464 12 P38159,P21333,Q9HCK8 3 +Hyperactive deep tendon reflexes 0.3912040828963223 0.6336957440555543 0.5262794029691413 1.0 0.9358230103103464 10 P51608 1 +Selective tooth agenesis 0.5116667508418473 0.6331906595292358 0.5266091445601495 1.0 0.9358230103103464 5 P21333 1 +Prominent nasal tip 0.6632751253516598 0.631441508231477 0.5277518829215706 1.0 0.93605458012845 3 O75147 1 +Periorbital edema 0.2928918611619403 0.6287159857515078 0.529535010684576 1.0 0.9374282646290378 28 Q9Y448,Q9Y5K6,Q14331,Q8NFV4,Q15056,Q01082,Q9UIG0 7 +Anophthalmia 0.3553976801292527 0.625441574280434 0.5316812832081554 1.0 0.9394383737902277 14 O15078 1 +Severe postnatal growth retardation 0.3767237661600795 0.6247269179130188 0.5321503031554953 1.0 0.9398428930016748 12 Q9UQE7,P54132,Q14683 3 +Increased urine alpha ketoglutarate concentration 0.5506998775787435 0.6244764708558885 0.5323147179643659 1.0 0.9398428930016748 4 P09622 1 +Facial edema 0.2918026351210344 0.6234028367372854 0.5330198343093688 1.0 0.94000567814809 29 Q9Y448,Q9Y5K6,Q14331,Q8NFV4,Q15056,Q01082,Q9UIG0 7 +Polycystic kidney dysplasia 0.3413730124880887 0.6227913096488524 0.5334216698528085 1.0 0.94000567814809 16 Q6ZRS2,Q6P1J9,O00192,Q14697,Q8NCM8,P38117 6 +Peripheral pulmonary artery stenosis 0.3762192656000259 0.6218444935599414 0.5340441263298967 1.0 0.94000567814809 12 O43709,Q8NFV4,Q15056,Q9UIG0 4 +Enlarged posterior fossa 0.2655383822032642 0.6214653496754261 0.5342934861710527 1.0 0.94000567814809 59 Q7Z3K3,Q9P2D1,Q9UBM7,O14802,P36543,P24928,Q9BPU6,P19022,O60826,O75369,Q92785,Q8NCM8,O15078,Q96L73 14 +Intractable diarrhea 0.5497631183302762 0.6209059701816371 0.5346614927994235 1.0 0.94000567814809 4 Q15477,Q15149 2 +Abnormality of facial musculature 0.2515516380373863 0.6208468696842259 0.5347003815190106 1.0 0.94000567814809 89 Q9Y281,P51608,Q14331,P54098,Q13049,Q9P2D1,Q96JM3,Q6P1N0,P25490,Q14203,Q99496,Q9H1B7,P11047,Q15149,O75190,P51610,Q9BZI7,Q14315,Q14692,P55072 20 +Aplasia hypoplasia of the humerus 0.3886467152241686 0.6198334832422739 0.5353674218884255 1.0 0.94000567814809 10 P21333,O75369,O14802 3 +Abnormality of the lymph nodes 0.278010382464766 0.6176022202316908 0.5368375806953836 1.0 0.94000567814809 42 P06748,Q9UER7,Q9P2D1,Q99496,Q14980,Q8NBM4,P33991,Q6UN15,Q01844 9 +Thin upper lip vermilion 0.262724224562286 0.6173579421362401 0.5369986565067533 1.0 0.94000567814809 101 Q14683,P51608,O75179,Q7Z6Z7,Q92785,Q92974,O15344,Q15233,Q7Z3K3,Q12830,Q8WXI9,P19022,Q9BSJ2,Q96KP1,P11274,Q9UQE7,Q9UGM6,Q7LBC6,Q01082,Q9H2P0,P11166,O14802,P42345,P51610,Q9BZI7,O60828,O94992,P35573 28 +Furrowed tongue 0.3878681143434428 0.6156293177879274 0.5381391970264049 1.0 0.94000567814809 10 O15078 1 +Skin nodule 0.3144698462795421 0.6148310659131612 0.5386662909293156 1.0 0.94000567814809 23 O75874,Q15437,P48735 3 +Bulbar palsy 0.381307709969902 0.6130529820122522 0.5398413077761484 1.0 0.94000567814809 11 O75190,P43243 2 +Abnormal renal pelvis morphology 0.2643732437159325 0.6129556463057313 0.5399056674592253 1.0 0.94000567814809 60 Q6ZRS2,Q9P2D1,Q9UBM7,O14802,O60934,Q8NCM8,P98175,O60826,Q5JRA6,P21333,Q15042,Q15149,Q96L73,P25490 14 +Abnormal middle phalanx morphology of the hand 0.4092457302491538 0.6127683712818568 0.540029507034208 1.0 0.94000567814809 8 O60828,P02545,Q9Y448 3 +Dysphasia 0.3309970609057485 0.6123357590014026 0.5403156353958023 1.0 0.94000567814809 19 Q13428,Q9UQN3,P17480,P55072,Q15149 5 +Increased susceptibility to fractures 0.2653786678358377 0.6116296508628458 0.5407828158596837 1.0 0.94000567814809 57 Q9P2D1,Q8N1G0,Q96AY3,O75874,P48735 5 +Aplasia hypoplasia of the phalanges of the hand 0.2652675047940529 0.6103505714146327 0.5416296036019315 1.0 0.94000567814809 57 Q9Y448,Q9UQE7,Q14683,O60885,P42345,P51610,P51608,Q04721,Q9Y366,Q9BZI7,P02545,O60826,Q5JRA6,O75369,P21333,Q6UX04 16 +Cerebral white matter hypoplasia 0.4361302126264347 0.6096239950930386 0.542110912816832 1.0 0.94000567814809 7 Q9UGM6 1 +Gastrointestinal stroma tumor 0.6567653155174722 0.6090538444247021 0.5424887496089839 1.0 0.94000567814809 3 Q05655 1 +Neck muscle weakness 0.3338113785765866 0.6083983974156891 0.542923274117914 1.0 0.94000567814809 18 Q9Y281,Q13049 2 +Sleep wake cycle disturbance 0.5445345845478188 0.6010817935054267 0.5477855091466615 1.0 0.9420203555174872 4 Q14683 1 +Generalized lymphadenopathy 0.6375413450937071 0.6010783780474727 0.5477877838999397 1.0 0.9420203555174872 2 Q05655 1 +Abnormal proportion of class switched memory b cells 0.6375413450937071 0.6010783780474727 0.5477877838999397 1.0 0.9420203555174872 2 Q05655 1 +Hypoplastic female external genitalia 0.3379981270225387 0.6008690520808648 0.5479272074787365 1.0 0.9420203555174872 16 Q9P2D1,Q15042,Q9UQE7,Q14683 4 +Mildly elevated creatine kinase 0.3070157477005057 0.5968213996256816 0.5506266289485722 1.0 0.9435844514078168 24 P43243,P02545,Q7Z406,P54098,Q14315,P55072 6 +Abnormality of alkaline phosphatase level 0.3013597494029837 0.5952246118534361 0.5516933407521063 1.0 0.9435844514078168 25 Q8N1G0,P11274,P14314,Q01130,Q96JJ3,Q96AY3,Q13043,Q9Y2V7,P55072 9 +Dysplastic corpus callosum 0.3710501213388266 0.5925229473553862 0.5535004590596431 1.0 0.9445892887440916 12 Q96ST3,P18583,O14974 3 +Entropion 0.39414234275185 0.589885188489438 0.5552676247814241 1.0 0.9454037576645532 9 P36543,O14802 2 +Short fourth metatarsal 0.6510751669284474 0.5896850495925798 0.5554018201902797 1.0 0.9454037576645532 3 Q15910 1 +Hydrops fetalis 0.2751370970246272 0.5890911628145906 0.5558001212535264 1.0 0.9455605516444828 42 P61254,P62273,P62913,P62081,O75369,P62857,P62899,P39019,Q8NCM8 9 +Pineal cyst 0.5402366639831354 0.5849235287832747 0.558599137058631 1.0 0.9479074476795508 4 Q12830 1 +Abnormal pineal morphology 0.5402366639831354 0.5849235287832747 0.558599137058631 1.0 0.9479074476795508 4 Q12830 1 +Abnormality of the pineal gland 0.5402366639831354 0.5849235287832747 0.558599137058631 1.0 0.9479074476795508 4 Q12830 1 +Downslanted palpebral fissures 0.3006273985136666 0.5836257488018802 0.5594721326897698 1.0 0.9479074476795508 153 Q96ST3,Q9UBM7,P55011,P51608,P36543,P18583,O95319,Q7Z6Z7,Q92785,Q13049,Q92974,O15078,Q6UX04,Q15233,Q9P2D1,Q12830,P19022,P25490,Q15910,Q9BPU6,O60826,P02545,Q9HCK8,P62857,P39019,Q9H2P0,Q9GZZ9,Q96L73,Q5F1R6,Q13428,O14802,P42345,P51610,Q9BZI7,P21333,Q8N3R9,Q14683 37 +Urethral valve 0.649262104917127 0.583554224992262 0.5595202648423561 1.0 0.9479074476795508 3 Q96L73 1 +Congenital posterior urethral valve 0.649262104917127 0.583554224992262 0.5595202648423561 1.0 0.9479074476795508 3 Q96L73 1 +Frontotemporal cerebral atrophy 0.6492602618451193 0.5835480028936644 0.5595244521164209 1.0 0.9479074476795508 3 Q9UQN3 1 +Spoken word recognition deficit 0.6492602618451193 0.5835480028936644 0.5595244521164209 1.0 0.9479074476795508 3 Q9UQN3 1 +Recurrent viral infections 0.3344336301589665 0.5779632761938948 0.5632889132519683 1.0 0.951164091526852 16 Q5F1R6,Q13432,Q9Y448,P33991,P54132 5 +Aplasia hypoplasia of the ribs 0.2991203660801489 0.5773838330131175 0.5636801930419408 1.0 0.951343301613022 25 Q15910,O60826,O75369,P39019,Q8NCM8,Q6ZRS2 6 +Diaphragmatic eventration 0.4978293881525957 0.5771998071413519 0.5638044873342507 1.0 0.951343301613022 5 Q15650,P38935,Q68CP9 3 +Cystoid macular edema 0.5372311086596805 0.5737006582989163 0.566170382774611 1.0 0.9525683449506216 4 P50213,P36405,Q6P2Q9 3 +Increased circulating prolactin concentration 0.4007403332095847 0.5706361021475118 0.5682463409190199 1.0 0.9557150728377436 8 Q99496,Q969G3,O14802 3 +Midface retrusion 0.2438907876264673 0.5686997230600656 0.5695599357908674 1.0 0.9557917051588738 85 Q8NC56,Q8TD16,P51608,P18583,O75179,P35573,Q7Z3K3,O75147,Q12830,P50454,Q9BSJ2,Q14807,P02545,O75369,P62857,Q15042,Q13428,P42345,P51610,Q9Y366,Q9BZI7,P21333,Q14683 23 +Abnormality of bladder morphology 0.373062803037303 0.5679233412881677 0.5700870219393823 1.0 0.9557917051588738 11 O43709,Q8NFV4,Q15056,Q15149,Q9UIG0 5 +Excessive salivation 0.2841169171064461 0.5674587378460079 0.5704025527432306 1.0 0.9557917051588738 31 O14802,P51610,P51608,P09417,Q9BZI7,Q03252,Q15233 7 +Agenesis of maxillary incisor 0.6281697905182041 0.5669324795154527 0.5707600563407875 1.0 0.9557917051588738 2 P54132 1 +Agenesis of lateral incisor 0.6281697905182041 0.5669324795154527 0.5707600563407875 1.0 0.9557917051588738 2 P54132 1 +Torsade de pointes 0.6281697905181831 0.5669324795153782 0.5707600563408382 1.0 0.9557917051588738 2 P0DP25 1 +Primary amenorrhea 0.2846157563003149 0.5659720485874783 0.5714127817958907 1.0 0.9558514028097568 30 Q9P2D1,Q9UQE7,Q14683,O60885,P54098,P82650,Q15031,Q9H7N4,P51809 9 +Atrophy degeneration involving the corticospinal tracts 0.3321315408014149 0.563311972794465 0.5732224667333135 1.0 0.957138259702248 16 Q14203,O75298,Q8NFV4,Q15056,P55072,Q9UIG0 6 +Meningioma 0.3780219465796498 0.5631597693202302 0.5733260949438685 1.0 0.957138259702248 10 Q99496,Q15437 2 +Carpal synostosis 0.3991848746407847 0.5630249628981521 0.5734178857351104 1.0 0.957138259702248 8 O75369 1 +Synostosis of carpals tarsals 0.3991848746407847 0.5630249628981521 0.5734178857351104 1.0 0.957138259702248 8 O75369 1 +Epicanthus inversus 0.5339219402036381 0.5614195225698371 0.5745115783769974 1.0 0.9575879859102968 4 O14974 1 +Hemivertebrae 0.3553740890126419 0.5609692721407388 0.5748184848346125 1.0 0.9577560053877536 13 Q9P2D1,O60826 2 +Enlarged cisterna magna 0.3292094094692303 0.5592957182635019 0.5759599170425846 1.0 0.958311384788792 17 Q7Z3K3,P24928,P19022,O75369,Q96L73 5 +Bradycardia 0.3713824084835477 0.5588489265987749 0.5762648281009959 1.0 0.958311384788792 11 P47985,Q9H0U9,O43772,P02545 4 +Cephalohematoma 0.6254134509371465 0.5570168411873149 0.577515922749265 1.0 0.958311384788792 2 P17301 1 +Difficulty climbing stairs 0.3259665244058077 0.5560775678090762 0.5781578293433558 1.0 0.958311384788792 18 O75190,P54098,Q14315,P55072,Q15149 5 +Weak voice 0.4511088438162318 0.5560420499817588 0.5781821090805015 1.0 0.958311384788792 6 P43243,Q14203 2 +Joint stiffness 0.2564451916862317 0.555337902072727 0.5786635586023292 1.0 0.958311384788792 65 Q15910,Q9UQE7,Q14683,O60885,P51608,Q96AY3,Q8NFV4,O14974,Q15056,P02545,O75874,Q9UBC1,P21333,Q15042,P48735,Q9UIG0,Q96L73 17 +Decreased activity of mitochondrial complex iii 0.4242894707616277 0.5551485196468905 0.5787930778528227 1.0 0.958311384788792 7 P53597,Q96RP9 2 +Bronchiectasis 0.3190688814392693 0.5546081210250673 0.5791627330677094 1.0 0.958311384788792 20 O60934,Q92888,P54132 3 +Paranoia 0.4501046883139036 0.5517636966874512 0.5811102628551033 1.0 0.958311384788792 6 Q96DF8 1 +Abnormal endocardium morphology 0.3301106121839389 0.5505457542468141 0.5819451036388295 1.0 0.958311384788792 16 Q8NBM4,Q8NFV4,Q15056,Q9UIG0,P18206 5 +Displacement of the urethral meatus 0.2813004176739078 0.548842549319654 0.5831135073411446 1.0 0.958311384788792 129 Q96ST3,Q9UBM7,O60885,O60832,P51608,P53597,P62913,Q7Z6Z7,Q92785,O15344,O75147,Q71SY5,Q969G3,Q04721,Q8WXI9,O14974,Q15555,P06748,Q9UQE7,P61254,Q9NPE3,P62273,O60826,P62081,P02545,P62899,Q7LBC6,Q01082,P62857,P39019,P46777,P61353,Q6ZRS2,Q96L73,O14802,P42345,P22314,O60828,P21333,Q14683 40 +Visual acuity test abnormality 0.4906258488094894 0.5486460220078484 0.5832483960303241 1.0 0.958311384788792 5 Q12824,Q99496,Q969G3 3 +Abnormal number of incisors 0.4489670782597812 0.5469285865416044 0.5844277953599026 1.0 0.9586107688544762 6 Q14683 1 +Abnormality of the urethra 0.292682195952284 0.546902788545953 0.5844455198457301 1.0 0.9586107688544762 145 Q96ST3,Q9UBM7,O60885,O60832,P51608,P53597,P62913,Q7Z6Z7,Q92785,O15344,Q9UIG0,O15078,O75147,Q71SY5,O43709,Q969G3,Q04721,Q8NFV4,Q8WXI9,O14974,Q15555,P06748,Q9UQE7,P61254,Q9NPE3,Q15056,P62273,O60826,P62081,P02545,P62899,Q7LBC6,Q01082,P62857,P39019,P46777,Q15149,P61353,Q6ZRS2,Q96L73,O14802,P42345,P22314,O60828,P21333,Q8NCM8,Q14683 47 +Abnormality of the axillary hair 0.4489260495426078 0.5467544417955952 0.5845474461781106 1.0 0.9586107688544762 6 Q8IY37,P51809,Q9H7N4 3 +Incomitant strabismus 0.3243536651396744 0.5455001151421147 0.5854096013564165 1.0 0.9592378058897276 18 P55011,Q12830,Q9BPU6,Q7Z6Z7,Q8N3R9 5 +Epiphora 0.5288305474747723 0.5426839864051165 0.5873474017041063 1.0 0.9610575266616134 4 Q9NPE3 1 +Generalized tonic seizure 0.3264989602361008 0.5418929744228688 0.5878922368949651 1.0 0.9612720706723796 17 Q96N67,Q96T60,Q96JM3 3 +Wide cranial sutures 0.4212086439450694 0.541221218120742 0.5883551142925152 1.0 0.9616905438330348 7 P98175,O14802 2 +Diastasis recti 0.5279000390040113 0.5392813967410726 0.5896927032331392 1.0 0.962890028227978 4 P42345,Q15910 2 +Spastic gait 0.2826379053916027 0.538955185731489 0.5899177771390258 1.0 0.962890028227978 27 O75298,P51608,P40818,Q9BRK0 4 +Full cheeks 0.2714675687786178 0.5373155166520504 0.59104968907346 1.0 0.9642312940626966 40 P10412,Q04721,P18583,Q96JJ3,Q8N201,Q9Y366,P02545,Q01082,P21333,O75845,O15078 11 +Abnormality of secondary sexual hair 0.3936739347392548 0.5363082181498374 0.5917455517957455 1.0 0.9643435007930916 8 Q8IY37,P82650,P51809,Q9H7N4 4 +Impaired tandem gait 0.3196880133131354 0.5355592141392279 0.5922632231008738 1.0 0.9646853129161445 19 O75175,P55011,Q12830,Q9BPU6,Q7Z6Z7,Q8N3R9 6 +Spina bifida 0.2718798397205757 0.5349548763328797 0.5926810603112831 1.0 0.9650276409483296 39 Q96ST3,O43709,Q8NFV4,Q15056,Q9Y2W2,O75369,P21333,Q9UIG0,O15078 9 +Vertebral segmentation defect 0.2774792105087302 0.5330956598786091 0.5939673632808848 1.0 0.9653679473495476 34 Q9P2D1,Q8NFV4,Q15056,P18583,Q9Y2W2,O60826,O75369,P21333,Q9UIG0 9 +Dysgraphia 0.327178661885922 0.5321894505683072 0.594594788745971 1.0 0.9653679473495476 16 Q9UQN3,Q8NFV4,Q15056,P55072,Q9UIG0 5 +Gingival bleeding 0.3502560491003845 0.5318017631538638 0.5948633014860896 1.0 0.9653679473495476 13 P06748,P49257,Q14980,Q02241,Q6UN15 5 +Male sexual dysfunction 0.3596481651080193 0.5293273727995818 0.59657837016845 1.0 0.9661204700539584 12 Q9P2D1,O75298,Q969G3,Q99496,P20700,Q06787 6 +Severe infection 0.3921480656560132 0.5289820188856555 0.5968179234893711 1.0 0.9661204700539584 8 P51608 1 +Progressive proximal muscle weakness 0.6326900667737663 0.5284865463293834 0.59716168242235 1.0 0.9662292263985586 3 Q15149 1 +Esophageal stricture 0.4853863158164933 0.5281561477640532 0.5973909630314425 1.0 0.966263767910586 5 Q9NPE3,O60832 2 +Gingival overgrowth 0.2806034306147472 0.5275213095148997 0.5978316223313143 1.0 0.9665792132982172 29 P06748,Q9UBM7,O43709,O75845,Q14980,Q8NFV4,Q15056,Q6UN15,Q9UIG0 9 +Abnormal eyelash morphology 0.2384598400416555 0.5214134629606096 0.6020787748630254 1.0 0.969437382907154 83 Q9UBM7,Q96GM5,O60885,O60832,Q14331,Q96N67,Q92785,O15160,Q92974,Q6UX04,Q969G3,Q04721,P62304,P46778,P06748,Q9UQE7,Q9NPE3,Q99496,P02545,P26640,P54132,Q13724,O94979,P20700,Q6ZRS2,Q13428,O14802,O94992,Q14683 29 +Abnormal ciliary body morphology 0.5227078152027667 0.5204212763589009 0.6027699839476148 1.0 0.96990031696834 4 P11047 1 +Abnormality of lower lip 0.245356184884972 0.5172401261272195 0.604988544377179 1.0 0.9713587100569336 73 Q96ST3,P51608,P38159,Q7Z6Z7,Q96N67,Q92785,Q9UIG0,Q9Y448,O75147,Q8NFV4,Q96JM3,P25490,Q15056,Q9H2P0,Q15042,Q7L2E3,P11166,P51610,Q9Y366,Q9BZI7 20 +Otitis media 0.2538145797446866 0.5161385859640831 0.6057576199914849 1.0 0.9713587100569336 64 Q13432,Q9UBM7,O14802,O60934,Q99496,Q12830,Q8NFV4,P62913,Q15056,Q92785,P54132,Q01082,P21333,Q9UIG0,Q6ZRS2,Q96L73 16 +Vestibular dysfunction 0.2777613906996226 0.5131042070476379 0.6078784288175083 1.0 0.9728497172308754 31 Q9UM54,Q14980,Q8NBM4,P54098,Q6UN15 5 +Abnormality of facial adipose tissue 0.5206475033496583 0.5129982183164729 0.6079525669977324 1.0 0.9728497172308754 4 Q03252,O14802 2 +Abnormality of the achilles tendon 0.3365281211112762 0.5124768361879819 0.6083173278640097 1.0 0.9728816031595736 14 Q8TD16,P02545,Q15149,P50402 4 +Hyperlordosis 0.2568780558657059 0.5123712517930678 0.6083912069683066 1.0 0.9728816031595736 54 Q9Y281,Q9Y448,O75147,Q8TD16,O43709,Q14331,P18583,Q8NFV4,Q15056,P02545,O75369,P55072,Q15042,Q15149,Q9UIG0 15 +Horizontal ribs 0.6271266307990838 0.510416037100602 0.6097600238879646 1.0 0.9740649126873052 3 Q8NCM8 1 +Gastrointestinal infarctions 0.611631753031964 0.5083667448435902 0.6111961700020956 1.0 0.9740785603511716 2 P01889 1 +Subarachnoid hemorrhage 0.6255858836503966 0.5054507298345831 0.6132422957200276 1.0 0.976606219400606 3 P17301,P31153 2 +Poor appetite 0.3206027675822384 0.504655048326352 0.6138011386265774 1.0 0.9768266750677072 17 P42771,Q9UER7,Q8NC56,P11274,P54098,P54132,Q8WX93 7 +Abnormality of the proximal phalanx of the thumb 0.6244176429100115 0.5016974309293905 0.615880371930416 1.0 0.978691682526702 3 O60828 1 +Upslanted palpebral fissure 0.2447778957633594 0.4999961795780897 0.6170777675307195 1.0 0.9788830867779394 91 Q96ST3,Q13409,Q9UBM7,O14802,O60934,Q14683,P51608,Q12830,Q8WXI9,O14974,Q96JM3,O60826,O75179,Q7Z6Z7,Q9BSJ2,Q96KP1,O60828,Q15233 18 +Scleroderma 0.4377168528914421 0.499822886054527 0.6171997943316898 1.0 0.9788830867779394 6 Q9Y2U8,P02545 2 +Abnormality of facial soft tissue 0.2772938667260082 0.4956543713669569 0.6201382848306782 1.0 0.9811993904011448 129 Q9Y281,Q9UBM7,P51608,Q14331,P54098,Q15437,Q13049,Q03252,Q9UIG0,Q9P2D1,Q7Z3K3,Q9Y448,Q9Y5K6,Q8NFV4,Q96JM3,Q6P1N0,P25490,Q14203,Q99496,Q9H1B7,P11047,Q15056,O60826,P02545,Q01082,Q15149,O14802,O75190,P51610,Q9BZI7,Q14315,Q14692,P55072 33 +Hemoptysis 0.4764388797079292 0.4937472012610633 0.6214847255712446 1.0 0.98199235624943 5 Q8NBM4,P31153 2 +Abnormality of the cervical spine 0.2707081171271945 0.491571339960319 0.6230224082145004 1.0 0.9837530176597972 121 Q9Y281,P51608,P62913,Q13049,O15078,Q9Y448,O60934,Q12830,P52815,Q9UQE7,P61254,P62273,O60826,P62081,O75369,P62899,P62857,P39019,Q92917,Q6ZRS2,P11166,O14802,Q8N201,Q14683 24 +Autistic behavior 0.3199785117830873 0.4895359284334071 0.624462324684901 1.0 0.9856917197047336 207 Q96ST3,P46821,Q9UBM7,Q9UQN3,O60885,P55011,P51608,P24928,P18583,O95319,O75380,Q8N183,Q15437,Q96N67,Q92785,O75179,Q7Z6Z7,Q9UIG0,O15078,Q15233,Q9P2D1,Q7Z3K3,O75175,P17480,O43709,Q12830,Q8NFV4,Q8WXI9,Q96JM3,P15311,P19022,Q9BU61,Q6PJT7,Q6P1N0,P25490,Q9UQE7,Q8TB37,Q9BPU6,Q15056,Q9HCK8,Q7LBC6,Q01082,Q9H2P0,Q12904,Q9GZY8,Q96L73,Q5F1R6,Q9GZZ9,Q96T60,P11166,P42345,P51610,P17980,Q8N201,Q9BZI7,P55072,P67870,O94992,Q8N3R9,Q14683 60 +Abnormality of the common coagulation pathway 0.3201816285070736 0.4892178341181358 0.6246874847851647 1.0 0.9857123062127878 16 P49257,Q14980 2 +Petechiae 0.3323766234429425 0.4885957663993132 0.6251279108840797 1.0 0.9860724378405696 14 P06748,Q14980,Q6UN15 3 +Abnormal circulating gonadotropin concentration 0.3320628094159896 0.4868063948639381 0.626395538119348 1.0 0.9867322256408848 14 Q99496,Q969G3,P82650,Q15031,Q8IY37,Q12824,Q06787,P51809 8 +Decreased activity of mitochondrial complex ii 0.5129473563455171 0.4855743700399215 0.6272689719269309 1.0 0.9873313414050524 4 P31040 1 +Central hypothyroidism 0.3574443164687004 0.4853709053142437 0.6274132668752141 1.0 0.9873313414050524 11 Q99496,Q969G3,Q9NW13,Q12824,Q14683 5 +Abnormality of the metaphysis 0.252486400121822 0.4824311448489366 0.62949970084509 1.0 0.9887878894874674 61 Q5F1R6,Q9P2D1,Q15910,Q9Y366,O75874,Q8NCM8,P48735,Q96L73,Q6UX04 9 +Hyperaldosteronism 0.6039140022050618 0.4818401931910374 0.6299194744170205 1.0 0.9887878894874674 2 Q01968 1 +Natal tooth 0.4331278655260416 0.481000983357658 0.6305157998270094 1.0 0.9887878894874674 6 P21333,O14802 2 +Abnormal motor evoked potentials 0.6036383682469583 0.4809028472424564 0.6305855490806576 1.0 0.9887878894874674 2 Q9UNE7 1 +Psoriasiform dermatitis 0.4730226191120638 0.4808134306609703 0.6306491038798032 1.0 0.9887878894874674 5 P78536 1 +Overriding aorta 0.3619272598447931 0.4805218815607563 0.6308563477834785 1.0 0.9887878894874674 10 Q8NFV4,Q15056,Q9UIG0 3 +Pituitary hypothyroidism 0.407434989217451 0.4803418839886944 0.6309843112252005 1.0 0.9887878894874674 7 Q99496,Q969G3,Q9NW13 3 +Hyperpigmentation of the skin 0.2480423293763885 0.4801721500409541 0.6311049882117126 1.0 0.9887878894874674 96 Q96ST3,O60832,P55011,Q15437,Q7Z6Z7,P40818,Q6UX04,Q9Y448,O60934,Q12830,Q9NW13,P06748,Q9NPE3,Q9BPU6,P02545,P33991,P54132,Q15149,Q96L73,P42345,Q9NP58,Q9Y2W2,Q8N3R9 23 +Hypergonadotropic hypogonadism 0.3302197052546095 0.4763430756887019 0.6338299818527431 1.0 0.9907191139151352 14 O14802,Q7LG56,P02545,P54098,Q8IY37,O15160,P51809 7 +Bowing of the arm 0.4717003922196336 0.4758390733767397 0.6341890305904248 1.0 0.990947015855314 5 P21333,O75369 2 +Abnormality of hair growth 0.4316930959709475 0.4751656214081309 0.6346689288243428 1.0 0.9911740658199774 6 P78536 1 +Hydrocele testis 0.380685239392024 0.4750049484494946 0.6347834462062814 1.0 0.9911740658199774 8 Q96L73 1 +Elevated urinary delta aminolevulinic acid 0.5098634547557919 0.4747373135227519 0.6349742186240741 1.0 0.9911740658199774 4 P08397 1 +Lymphoma 0.2737112110151714 0.468462095202504 0.6394541714095436 1.0 0.9950397409986848 28 P06748,Q9P2D1,O60934,Q9NPE3,Q01130,P54132 6 +Abnormal larynx morphology 0.2723660136936219 0.4683854014985961 0.6395090058164896 1.0 0.9950397409986848 31 Q9P2D1,O14802,P43243,P36543,O75369,P21333,Q8NCM8 7 +Absent septum pellucidum 0.2649647074783958 0.4678866186935922 0.6398656732246613 1.0 0.9951324576556227 38 Q13409,Q15910,P55011,P15311,O14974,Q6PJT7 6 +Recurrent gastroenteritis 0.5074448975154835 0.4662989204677298 0.6410015513701102 1.0 0.995713507431917 4 P78536 1 +Ecchymosis 0.3162910679440852 0.4658670936021913 0.6413106364845551 1.0 0.995713507431917 16 Q14980,P40818 2 +Pseudobulbar signs 0.34745903166142 0.4643319635515418 0.6424099268899726 1.0 0.9969488256225908 12 Q14203,P26358,P08397,O94979,Q15233 5 +Abnormal umbilicus morphology 0.2453399337613843 0.464156894709175 0.6425353416698212 1.0 0.9969488256225908 69 Q9NRZ9,Q9UIG0,Q02809,Q9P2D1,Q9Y448,O43709,Q04721,Q8NFV4,Q15910,Q99496,Q15056,P02545,Q7LBC6,Q9H2P0,Q6ZRS2,Q96L73,Q96T60,P42345,Q96JJ3,Q96DF8,P21333 21 +Posterior pharyngeal cleft 0.6123857589117542 0.4636410129613978 0.6429049652316274 1.0 0.997189376979764 3 O15344 1 +Abdominal aortic aneurysm 0.611800385993931 0.4618182422912009 0.6442116678439349 1.0 0.9974890834908196 3 P01889,P31153 2 +Synostosis of carpal bones 0.5059785515710882 0.4612092279240488 0.6446485017434331 1.0 0.9975629662343436 4 P21333 1 +Thyroiditis 0.352565749645359 0.4604741883218556 0.6451758944622141 1.0 0.997723530667654 11 Q9P2D1,P54098,Q15437 3 +Generalized neonatal hypotonia 0.4672376084093704 0.4591829903733923 0.6461027642926278 1.0 0.997723530667654 5 Q9H2P0,Q12830 2 +Tarsal synostosis 0.5050862004842791 0.4581217559673575 0.6468649693732498 1.0 0.997723530667654 4 O75369 1 +Synostosis involving bones of the lower limbs 0.5050862004842791 0.4581217559673575 0.6468649693732498 1.0 0.997723530667654 4 O75369 1 +Hirsutism 0.2477876105490793 0.4551893197944028 0.64897304342619 1.0 0.9998230716564834 65 P46821,O60885,Q92785,Q13049,Q9NQ48,Q03252,P40818,O15078,Q969G3,Q04721,Q9NR45,Q9UQE7,P02545,Q15042,Q9H2P0,Q6ZRS2,O14802,Q96JJ3,P21333,Q14683 20 +Abnormal midbrain morphology 0.3668220459210537 0.4549833767985856 0.649121198017562 1.0 0.9998230716564834 9 O15078 1 +Multiple joint dislocation 0.6093189964157673 0.4541221375071575 0.6497409205854916 1.0 1.0 3 Q14807,O94766 2 +Macrotia 0.245085646501405 0.4538762606587179 0.6499178908645331 1.0 1.0 95 Q96ST3,O60885,P55011,P51608,P38159,Q7Z6Z7,Q92785,Q9UIG0,Q6UX04,O75175,O60934,Q12830,Q8NFV4,Q15910,Q9UQE7,Q9BPU6,Q15056,O95721,Q15042,Q96L73,P11166,O60828,P21333,Q8N3R9,Q14683 25 +Rhabdomyolysis 0.3261605721434925 0.4535844022019314 0.6501279821198422 1.0 1.0 14 P54098,O43772,P53597 3 +Abnormal atrioventricular conduction 0.3359699293407748 0.4531441131100309 0.6504449722391734 1.0 1.0 13 O43772,P31040,P02545,P0DP25,P50402 5 +Synostosis involving bones of the hand 0.3452603041691722 0.4529214093725847 0.6506053339026137 1.0 1.0 12 O60828,P21333,O75369 3 +Chromosome breakage 0.3444605186020045 0.4487960462808811 0.6535787911265671 1.0 1.0 12 Q99496,Q969G3,P33991,P54132,Q92878,Q06787 6 +Heart block 0.2958443554256456 0.4486159384922426 0.653708734089812 1.0 1.0 22 Q8NC56,O43772,P36543,P02545,P19022,Q15149 6 +Abnormality of the 5th toe 0.3443329560042291 0.4481393261190081 0.6540526478452522 1.0 1.0 12 Q9NQ48,Q8NCM8,Q9UBM7,O15078 4 +Postaxial foot polydactyly 0.3443329560042291 0.4481393261190081 0.6540526478452522 1.0 1.0 12 Q9NQ48,Q8NCM8,Q9UBM7,O15078 4 +Hypokalemia 0.3746362973652147 0.4473301491571926 0.6546367016222359 1.0 1.0 8 Q9UNF1,P0DP25,P40818 3 +Respiratory paralysis 0.6064630244678482 0.4453263276903904 0.6560839443165758 1.0 1.0 3 P08397 1 +Elevated urinary dicarboxylic acid level 0.6064630244678482 0.4453263276903904 0.6560839443165758 1.0 1.0 3 P08397 1 +Porphyrinuria 0.6064630244678482 0.4453263276903904 0.6560839443165758 1.0 1.0 3 P08397 1 +Psychogenic non epileptic seizure 0.270103615602257 0.442397878389934 0.6582013140171781 1.0 1.0 29 O75175,P55011,P51608,Q12830,Q9BPU6,Q7Z6Z7,Q8N3R9,Q14683 8 +Multiple cafe au lait spots 0.3135178512348264 0.4409511004956549 0.6592483982097157 1.0 1.0 15 Q15437 1 +Generalized muscle weakness 0.265586786965481 0.4406223642358129 0.6594864094640027 1.0 1.0 35 P55084,Q14203,Q9UQN3,O75190,P43243,P11047,Q9NP58,P54098,P55072,P22314,Q15149,P25490 12 +Vocal cord paresis 0.4997178384592649 0.4397085559607853 0.6601482049587444 1.0 1.0 4 P43243,P36776 2 +Facial hypertrichosis 0.2496267440010365 0.4389607432941352 0.6606899815170131 1.0 1.0 57 P46821,Q9UQE7,O14802,O60885,Q04721,Q12830,P17980,Q9Y2U8,Q9NR45,P19022,Q96N67,Q13620,Q9BSJ2,Q01082,Q15042,Q7L2E3,Q14683 17 +Decreased activity of mitochondrial complex i 0.2641493907196892 0.4380876730485212 0.6613227299344595 1.0 1.0 36 Q8N183,O75380 2 +Abnormality of tibia morphology 0.3115320795257035 0.4378690180058188 0.661481235779626 1.0 1.0 16 Q9P2D1,Q8NCM8,O75369 3 +Combined immunodeficiency 0.3629399875409717 0.4367870729895328 0.6622657748231386 1.0 1.0 9 Q9P2D1 1 +Albuminuria 0.4601512819610724 0.4331737441342755 0.6648885518658145 1.0 1.0 5 Q5JRA6,Q14697 2 +Muscular dystrophy 0.2685021833663317 0.4330513340332946 0.6649774767754921 1.0 1.0 30 O75190,Q14331,P02545,Q5JTV8,Q13049,Q15149,Q96T60 7 +Lens subluxation 0.4972852551179346 0.4314578085216594 0.6661355243002456 1.0 1.0 4 Q9Y467 1 +Eruption failure 0.3958272563064717 0.4309801497628208 0.6664828039350961 1.0 1.0 7 P02545,O75369,P21333 3 +Aplasia hypoplasia of the hallux 0.2890369350891161 0.4305783582468063 0.6667749800039995 1.0 1.0 23 P55011,Q12830,Q9BPU6,Q7Z6Z7,P21333,Q8N3R9 6 +Abnormal brainstem morphology 0.2459319774449687 0.4289203206630275 0.6679812114972634 1.0 1.0 98 Q9Y3C6,Q96C36,Q9BVA1,O75380,Q8N183,Q96N67,Q9HD42,Q92974,Q6ZXV5,Q9UN37,O15078,P07942,Q7Z3K3,Q969G3,Q13813,Q96KP1,Q9BU61,Q13409,O95169,Q8IUX1,Q7Z460,P26358,Q99496,Q8TB37,Q9UGM6,O75489,O75251,P20700,P49792,Q13217,O94992,Q14683 32 +Sloping forehead 0.2487351018946769 0.4285139953881577 0.6682769463985927 1.0 1.0 56 Q13409,O60934,P98175,Q96KP1,O15078 5 +Abnormal circulating phenylalanine concentration 0.6007982649458369 0.4280811528527608 0.6685920379503991 1.0 1.0 3 P09417 1 +Sparse or absent eyelashes 0.2793245420779157 0.4274620882304382 0.6690427929797726 1.0 1.0 25 Q13428,O14802,Q9NPE3,O60832,P02545,P54132,P46778,Q6UX04 8 +Microdontia 0.267226128776733 0.4271232011605307 0.669289594898421 1.0 1.0 31 Q5F1R6,Q9UQE7,Q9NPE3,Q8NFV4,Q15056,Q9Y366,Q92785,Q9UIG0,Q6ZRS2 9 +Deeply set eye 0.2377573227111825 0.4243417211894426 0.6713166163876778 1.0 1.0 73 Q96ST3,P18583,O75179,Q7Z6Z7,P35573,Q9Y448,O75175,Q12830,Q8WXI9,P19022,P11274,Q99496,Q9BPU6,Q01082,Q15042,Q15149,Q6ZRS2,Q92917,O14802,Q14683 20 +Persistent head lag 0.3941633966755358 0.4240637869946045 0.6715192944930894 1.0 1.0 7 P51608,Q15233,Q01082 3 +Hypochromic anemia 0.3393683301024244 0.4228553391248124 0.6724008091770002 1.0 1.0 12 Q9Y4L1 1 +Chronic hepatic failure 0.4945211288808777 0.4221547090824664 0.6729120973515332 1.0 1.0 4 Q13043 1 +Lacrimal duct atresia 0.585722160970221 0.4215485632751695 0.6733545572327966 1.0 1.0 2 Q9NX14 1 +Aplasia hypoplasia of the thymus 0.3085730079450254 0.4207891915108452 0.6739090248923638 1.0 1.0 16 Q9P2D1 1 +Abnormal odontoid tissue morphology 0.2471066399338771 0.418278987297167 0.675743150967625 1.0 1.0 50 Q5F1R6,O75147,Q9UBM7,Q13428,O43709,Q96JJ3,Q96AY3,Q8NFV4,Q15056,P50454,Q9Y366,Q9Y2V7,Q5JRA6,O75369,Q15149,Q9UIG0 16 +Lacrimal duct stenosis 0.4558543316558849 0.4176761135818009 0.6761839388494164 1.0 1.0 5 Q9Y448,Q13428 2 +Broad columella 0.455753021004207 0.4173132904528144 0.6764492685477328 1.0 1.0 5 Q6UX04 1 +Amblyopia 0.2948149922807435 0.4172923223334774 0.6764646035966677 1.0 1.0 21 Q9UGM6,P10412,Q9H2P0,P21333 4 +Progressive leukoencephalopathy 0.5967399101966033 0.4158950365887368 0.677486811638282 1.0 1.0 3 P31040 1 +Morphological abnormality of the corticospinal tract 0.3035950149769408 0.4157036333464396 0.6776268822299023 1.0 1.0 18 Q14203,O75298,Q8NFV4,Q15056,P55072,Q9UIG0 6 +Developmental stagnation 0.3675122749362379 0.4155175850366789 0.6777630447164771 1.0 1.0 8 P51608,Q14683 2 +Myotonia 0.3582787735420125 0.4153020232049506 0.6779208203185738 1.0 1.0 9 P02545,O75190 2 +Epileptic spasm 0.2419004817293378 0.4147802329664595 0.6783027913356177 1.0 1.0 68 Q9Y3C6,P55011,P51608,O94903,Q96N67,Q71SY5,P15311,Q96JM3,P19022,Q13813,Q6PJT7,Q6P1N0,Q96N66,Q01082,Q12904,Q96T60,Q9GZY8,P67870,Q14683 19 +Congenital hypothyroidism 0.4922779922779837 0.4146625303592504 0.6783889657140914 1.0 1.0 4 Q9Y263,P21281,P10644 3 +Thin vermilion border 0.2775259784021532 0.4143781582625886 0.6785971822688506 1.0 1.0 138 Q96ST3,Q14683,O60885,P55011,P51608,P18583,O75179,Q7Z6Z7,Q92785,Q92974,O15344,Q15233,Q7Z3K3,Q9Y448,O75175,Q04721,Q12830,Q8WXI9,P19022,Q9BSJ2,Q96KP1,P11274,Q9UQE7,Q9BPU6,Q9UGM6,P02545,Q7LBC6,Q01082,Q15042,Q9H2P0,Q6ZRS2,P11166,O14802,P42345,P51610,Q9BZI7,O60828,O94992,Q8N3R9,O75845,P35573 41 +Confusion 0.3004494444714247 0.4130986144748177 0.6795343644955667 1.0 1.0 19 P08397,Q8NBM4,O14802 3 +Communicating hydrocephalus 0.4544861877822417 0.4127865328119207 0.6797630191378805 1.0 1.0 5 P11166 1 +Vertigo 0.2768856514061761 0.4100954607577342 0.6817359224042758 1.0 1.0 25 Q14980,Q8NBM4 2 +Painless fractures due to injury 0.5821389195148736 0.4100672806296688 0.6817565936230015 1.0 1.0 2 Q9H4A3 1 +Bruxism 0.3906614851808898 0.4096443178224402 0.6820668819654438 1.0 1.0 7 P51608,Q01082 2 +Abnormality of the antihelix 0.3421429313852817 0.4088819512788169 0.682626294920281 1.0 1.0 11 P98175,P21333 2 +Abnormal central sensory function 0.4529484538730824 0.4073171974419518 0.6837750334962778 1.0 1.0 5 Q99496,Q969G3 2 +Abnormality of the skull base 0.2403517349546138 0.4071143534213634 0.6839240018085855 1.0 1.0 69 Q7Z3K3,Q9P2D1,Q9UBM7,O75175,O14802,P36543,P24928,Q9BPU6,P19022,O60826,O75369,Q92785,P21333,Q8NCM8,O15078,Q96L73 16 +Abnormal toenail morphology 0.2460445987863434 0.4020621916242137 0.687638256932747 1.0 1.0 53 P06748,Q15910,O43709,O60832,Q9NPE3,Q8NFV4,Q15056,Q9Y366,P02545,Q92785,Q15042,Q9UIG0,Q96L73 13 +Abnormality of the supraorbital ridges 0.2757113036598508 0.4018300310779596 0.687809119143961 1.0 1.0 25 Q9Y448,P38159,P98175,Q9HCK8,P21333 5 +Cystic liver disease 0.3885084387867886 0.4008734188590963 0.6885133210519689 1.0 1.0 7 O15078 1 +Hallux valgus 0.2884979011140534 0.400272712029153 0.6889556643425385 1.0 1.0 22 Q6UX04,Q15233,Q8NFV4,Q15056,Q9UIG0,P25490 6 +Abnormality of the nasal septum 0.4506065647338898 0.3990419567684428 0.6898622893254862 1.0 1.0 5 O75369,Q15233 2 +Acquired abnormal hair pattern 0.4122215979949393 0.3984933430040417 0.6902665643846255 1.0 1.0 6 O60828,P02545,P11166 3 +Abnormality of vitamin a metabolism 0.4119679236948544 0.39752743751741 0.6909785576614904 1.0 1.0 6 Q5F1R6,Q13043,P61011,Q7Z2Z2 4 +Degeneration of the lateral corticospinal tracts 0.3631838635447866 0.3966258161898989 0.6916434122232755 1.0 1.0 8 O75298,Q14203 2 +Short femur 0.4113784658505344 0.3952864497877888 0.6926314983844182 1.0 1.0 6 O75369,O14802 2 +Bulbous nose 0.2476688593303737 0.3948068041281476 0.6929854730494056 1.0 1.0 48 Q13409,Q9UQE7,Q8N201,P38159,Q7Z6Z7,Q96N67,Q9BSJ2,Q96DF8,Q01082,O60828,P25490 11 +Delayed eruption of permanent teeth 0.4490116678072576 0.3934442932946851 0.6939913606200552 1.0 1.0 5 Q5JRA6,Q96L73 2 +Abnormal sputum 0.4104365927707423 0.3917157691785873 0.6952682372127252 1.0 1.0 6 Q8NBM4,P31153 2 +Multifocal epileptiform discharges 0.2626085430655488 0.3912607778787698 0.6956044873715928 1.0 1.0 31 Q71SY5,P55011,Q96N66,P15311,Q96N67,Q01082,Q6PJT7,Q6P1N0,Q12904,Q96T60 10 +Prolonged bleeding following procedure 0.5878676667328052 0.3897628960215346 0.696711882842675 1.0 1.0 3 P49257 1 +Abnormal distal phalanx morphology of finger 0.2446868338290448 0.3877073260217927 0.6982326336821882 1.0 1.0 55 Q9Y448,P11274,P42345,P51610,P51608,Q04721,Q8WXI9,Q9Y366,Q9BZI7,P02545,Q14807,O75369,O60826,Q01082,P21333,Q15042,Q6UX04 17 +Abnormality of the uterus 0.2441185344621017 0.3869556689810713 0.6987890272724244 1.0 1.0 59 Q9P2D1,Q9UQE7,O14974,Q15437,P20585,Q8NCM8,Q14683 7 +Sporadic 0.2781902763488872 0.3868285187431615 0.6988831627752405 1.0 1.0 24 Q9P2D1,P42345,O75369,Q03252,Q96L73 5 +Hypoplasia of the frontal lobes 0.3517786380341123 0.3860368673095539 0.699469364926365 1.0 1.0 9 Q96C36,Q9UBM7,P22570 3 +Abnormal brainstem mri signal intensity 0.2780085101696696 0.3856097902670954 0.6997856814105519 1.0 1.0 24 O75380 1 +Focal t2 hyperintense brainstem lesion 0.2897664559009459 0.3855819293426835 0.6998063185370773 1.0 1.0 21 O75380 1 +Melanoma 0.2731893447922885 0.3842982466457578 0.7007574073870593 1.0 1.0 25 Q92878,Q15437 2 +Aplasia hypoplasia of the nipples 0.2981850307128993 0.3840651206877571 0.7009301823166001 1.0 1.0 18 O60826,Q9UQE7,P10586,Q14683 4 +Frontal balding 0.5858768934914028 0.3839979626000444 0.7009799575676139 1.0 1.0 3 P11166 1 +Periodontitis 0.3365518467511293 0.3821734723325907 0.7023326971251329 1.0 1.0 11 P06748,Q9NPE3,O60832,Q04721 4 +Osteoporosis 0.2329574849371234 0.3819880024489646 0.70247026374634 1.0 1.0 74 O60832,Q96AY3,P62913,P54098,Q8IY37,Q9UIG0,P40818,Q02809,Q9P2D1,O43709,Q04721,Q8NFV4,Q13043,O14745,P51809,P06748,Q9NPE3,Q15056,P02545,Q15042,Q01130,Q9Y366,P82650,Q15031,O75845 25 +Mutism 0.3027252428004128 0.3808719230001841 0.703298287238241 1.0 1.0 15 P51608,Q15149,Q9UQN3,Q14683 4 +Premature loss of teeth 0.3219713923257991 0.3805890128274047 0.7035082353128737 1.0 1.0 13 O14802,O60832,Q04721,P02545,Q9NW13 5 +Disturbance of facial expression 0.4073430309667527 0.3800765630427397 0.7038885826378185 1.0 1.0 6 P51608 1 +Shortening of all distal phalanges of the fingers 0.3360722981060399 0.3799159140574912 0.7040078337963398 1.0 1.0 11 P51610,P51608 2 +Motor regression 0.5724917309812458 0.3798432449494328 0.7040617791071391 1.0 1.0 2 P51659 1 +Colon cancer 0.2994798207858963 0.3792445246462705 0.7045062908193391 1.0 1.0 17 P20585 1 +Rectal prolapse 0.3408020093755012 0.3791780632201844 0.7045556404244964 1.0 1.0 10 Q8NFV4,Q15056,Q9UIG0 3 +Atrioventricular canal defect 0.3502095158792003 0.3790988214248768 0.7046144814630511 1.0 1.0 9 P19022,O60826 2 +Myalgia 0.2459367076471738 0.3789282180288605 0.7047411691073742 1.0 1.0 48 P55084,P31040,Q14739,P54098,Q13049,O00192,Q8NBM4,Q9Y2U8,P50570,Q8IUX1,Q7LG56,P02545,P20700,O14802,Q01130,P43243,Q14315,P55072,Q06787 19 +Fatigable weakness of swallowing muscles 0.3216199474705506 0.3788314489906406 0.7048130320530646 1.0 1.0 13 P43243,Q14203,Q9UQN3 3 +Atopic dermatitis 0.5839536807278707 0.3784638263326371 0.705086061226539 1.0 1.0 3 Q8TD19,P38646 2 +Impaired distal proprioception 0.4811261691700763 0.3782084725196693 0.7052757319642338 1.0 1.0 4 O14802 1 +Abnormality of the maxilla 0.2595280550113276 0.3776134604444359 0.7057177638349921 1.0 1.0 33 P06748,Q13428,Q9NPE3,P18583,Q9BZI7,O75369,Q9BSJ2,O60828,Q6ZRS2 9 +Abnormal size of pituitary gland 0.4066809542976252 0.3776034406797697 0.7057252083251702 1.0 1.0 6 Q99496,Q969G3 2 +Absent facial hair 0.3402469154519887 0.3766397805538427 0.7064413205731153 1.0 1.0 10 Q13428,Q6UX04 2 +Vertebral clefting 0.3583887458694484 0.3761027097711978 0.7068405398679509 1.0 1.0 8 O75845,O75369,P36776,Q9Y2W2 4 +Atrial arrhythmia 0.3351227138321687 0.3754614289692511 0.7073173269299748 1.0 1.0 11 P02545,P54098,Q14315,P07741,P50402 5 +Branchial anomaly 0.3489034906782903 0.3733627044646327 0.7088785133738642 1.0 1.0 9 Q13428,P11274 2 +Frontal cortical atrophy 0.2931687815369306 0.3699312633198932 0.7114337065194449 1.0 1.0 19 P55011,Q12830,Q9BPU6,Q7Z6Z7,P55072,Q8N3R9 6 +Perseveration 0.3807418144688922 0.3698560180214589 0.7114897737444248 1.0 1.0 7 Q9UQN3,Q15233 2 +Abnormal morphology of the abdominal musculature 0.3476446929896468 0.3678676300018994 0.7129719378488577 1.0 1.0 9 P42345,Q15910,O75369 3 +Cerebellar cyst 0.2445532325894649 0.3664272847574086 0.7140462630910314 1.0 1.0 48 Q9P2D1,O14802,O60826,Q92785,Q8NCM8,O15078 6 +Abnormal atrioventricular valve physiology 0.2418688411802886 0.3626927812593616 0.7168343927897132 1.0 1.0 58 Q9UER7,P39019,O43709,Q99496,P36543,Q04721,Q8NFV4,Q8NBM4,Q15056,P54098,P19022,P02545,Q14315,P46777,Q9BU61,P21333,Q9UIG0,Q15233 18 +Abnormal megakaryocyte morphology 0.4399128035175414 0.36211800732867 0.7172638476338302 1.0 1.0 5 P62263 1 +Underdeveloped nasal alae 0.2649345891946704 0.3612906987413067 0.7178821461453555 1.0 1.0 26 Q96ST3,P11274,O75369,Q96DF8,Q15149,Q6UX04 6 +Tube feeding 0.2297693432986605 0.3592382629349238 0.7194168547556252 1.0 1.0 75 Q6ZRS2,Q9Y448,Q14683,P17480,P55011,P18583,P15311,Q96JM3,P25490,Q9H2P0,Q6PJT7,Q6P1N0,Q9GZY8,Q15233 14 +Axonal loss 0.3543162441522697 0.3590206641715834 0.7195796306692033 1.0 1.0 8 P17480,P35251 2 +Missing ribs 0.3081636249484915 0.3578742185458986 0.720437445267587 1.0 1.0 14 P39019,O60826,O75369 3 +Uveitis 0.3356333298136739 0.3558119433782389 0.7219814041553674 1.0 1.0 10 P01889,P29401,P50851,Q13043,P54132,Q05655 6 +Laryngotracheomalacia 0.4373811834825981 0.3535918444015746 0.7236447872379792 1.0 1.0 5 O75369 1 +Persistence of primary teeth 0.4000338313879744 0.3531325591788438 0.7239890646057661 1.0 1.0 6 P21333,Q6ZRS2 2 +Gonadal dysgenesis 0.3301508079079072 0.3524890670558905 0.7244715162436264 1.0 1.0 11 P18074,O14974,P82650,Q8IY37,P51809 5 +Abnormal fingertip morphology 0.2573723489333854 0.352080744227722 0.7247777088758451 1.0 1.0 31 Q15910,O75175,P55011,Q12830,Q9BPU6,Q7Z6Z7,Q8N3R9,Q6ZRS2 8 +Congenital malformation of the left heart 0.4368003834481853 0.3516477729787994 0.7251024329237716 1.0 1.0 5 O14802 1 +Increased circulating igg level 0.4724214009928194 0.3507182590781877 0.7257997258728346 1.0 1.0 4 Q05655,P29144,O95394 3 +Abnormality of the larynx 0.2400449510715301 0.3491426662756592 0.7269822065212228 1.0 1.0 51 Q9P2D1,Q14203,Q9UBM7,Q9UQN3,O14802,P36543,P43243,P02545,O75369,Q01082,P21333,Q8NCM8 12 +Abnormal delivery 0.2679547147413341 0.3488985532994636 0.7271654713186546 1.0 1.0 25 Q9UBM7,Q8NC56,O14802,P18583,P50454,P02545,P33991,Q7LBC6,Q01082 9 +Abdominal pain 0.2307120906432608 0.3466308477465574 0.7288686679661014 1.0 1.0 89 Q9NWH9,P31040,P54277,P54098,Q9UIG0,P40818,Q9UER7,O43709,Q9Y5K6,Q8NBM4,Q8NFV4,Q6P1J9,Q9NQW6,Q13043,P50336,Q8WX93,P07741,P61011,Q01844,P06748,P42771,P78347,Q13263,Q14980,Q7LG56,Q15056,P08397,Q01082,O43707,P14314,Q01130,P36957,Q6UN15 33 +Increased head circumference 0.2674208383900457 0.3461349969927349 0.7292412633450003 1.0 1.0 132 Q8TD16,P55011,P51608,P18583,Q15437,O75179,Q7Z6Z7,Q6UX04,P07942,Q15233,O75147,O75175,Q04721,Q12830,O14974,P50454,P19022,P10412,Q15910,Q9BPU6,O60826,P02545,Q9HCK8,Q01082,Q96L73,P11166,O14802,P42345,P51610,Q9BZI7,Q8NCM8,Q8N3R9,Q14683 33 +Hyperacusis 0.342583823848938 0.3461157852273397 0.7292557008614335 1.0 1.0 9 P78347,O43709,Q8NFV4,Q15056,Q9UIG0 5 +Loss of ability to walk 0.2934357545214472 0.3459942037964786 0.7293470707400327 1.0 1.0 17 P31040,O75190,Q7LG56,P51608,Q9H269,Q96D71,Q15149,Q14683 8 +Abnormal aortic valve physiology 0.2482988686021894 0.3458301127336299 0.7294703932024775 1.0 1.0 42 P11274,O43709,P36543,Q04721,P18583,Q8NFV4,Q8NBM4,Q15056,P02545,O60826,Q01082,P21333,Q6ZXV5,Q9UIG0 14 +Distal lower limb muscle weakness 0.2886163643096672 0.3439417908286039 0.7308900624359698 1.0 1.0 19 P02545,Q14315,Q15149,Q96T60 4 +Limited extraocular movements 0.3420075310301 0.3436741310578241 0.7310913678745765 1.0 1.0 9 Q9BU61,O95169,P11047,Q9BVA1 4 +Oromotor apraxia 0.4340763179709728 0.3425901682782585 0.7319067995314041 1.0 1.0 5 Q14683 1 +Inflammatory abnormality of the eye 0.2461174033473344 0.3410374639494959 0.7330753783845534 1.0 1.0 44 P06748,P29401,Q9UQE7,O60885,O60832,Q9NPE3,Q99496,Q8NBM4,P54132,P78536,Q15149,Q14683 12 +Ear pain 0.4692614933909478 0.3409587140775932 0.7331346627399471 1.0 1.0 4 Q99496,Q969G3 2 +Decreased circulating follicle stimulating hormone concentration 0.4692614933909478 0.3409587140775932 0.7331346627399471 1.0 1.0 4 Q99496,Q969G3 2 +Neuralgia 0.4692614933909478 0.3409587140775932 0.7331346627399471 1.0 1.0 4 Q99496,Q969G3 2 +Intracranial meningioma 0.4692614933909478 0.3409587140775932 0.7331346627399471 1.0 1.0 4 Q99496,Q969G3 2 +Brain stem compression 0.4692614933909478 0.3409587140775932 0.7331346627399471 1.0 1.0 4 Q99496,Q969G3 2 +Progressive pulmonary function impairment 0.4692614933909478 0.3409587140775932 0.7331346627399471 1.0 1.0 4 Q99496,Q969G3 2 +Hypothalamic hypothyroidism 0.4692614933909478 0.3409587140775932 0.7331346627399471 1.0 1.0 4 Q99496,Q969G3 2 +Tall stature 0.2380458016679333 0.3404690899971801 0.7335032964778303 1.0 1.0 63 Q15910,O14802,P55011,P36543,Q12830,Q9BZI7,P54098,Q7Z6Z7,Q9HCK8,Q13049,Q8N3R9,Q96L73,Q15233 13 +Sagittal craniosynostosis 0.373114947674649 0.3403911331008082 0.7335619952247865 1.0 1.0 7 Q92785 1 +Prominent nasal bridge 0.2395552253032677 0.3393729776179512 0.7343287726898637 1.0 1.0 57 Q96ST3,Q9UQE7,Q14683,O60934,P51608,Q9BZI7,O95721,Q96N67,Q5JRA6,Q13049,Q9NQ48,O15078,Q15233 13 +Abnormal cardiomyocyte morphology 0.5589856670341669 0.3392984304443707 0.7343849249209369 1.0 1.0 2 P46976 1 +Abnormal lower motor neuron morphology 0.3408405674009496 0.3387524189408843 0.7347962482365535 1.0 1.0 9 P43243,Q14203,Q9UQN3 3 +Abnormality of the thymus 0.2919812353424118 0.3381865369569749 0.7352226207416357 1.0 1.0 17 Q9P2D1 1 +Limb girdle muscular dystrophy 0.3489088191655941 0.336854071482178 0.7362269094826259 1.0 1.0 8 P02545,P50402 2 +Abnormal pons morphology 0.2660455260309973 0.3363334497506041 0.7366194283840315 1.0 1.0 25 Q9Y3C6,Q96N67,Q92974,Q9UN37,O15078 5 +Neurodegeneration 0.2557796377732028 0.3353513199820896 0.7373600849208302 1.0 1.0 29 Q14203,Q9UQN3,P17480,O60934,P43243,Q8TDP1,Q01082 7 +Hyporeflexia of lower limbs 0.3262896654561013 0.3350675139285249 0.737574157917471 1.0 1.0 11 P02545,Q14315 2 +Abnormal pancreas morphology 0.2869947131787239 0.3348792394181757 0.7377161833471433 1.0 1.0 19 Q5F1R6,O15078 2 +Intestinal polyp 0.2779735564793603 0.3348539571074727 0.7377352558145394 1.0 1.0 22 P20585 1 +Third degree atrioventricular block 0.5683045009372835 0.3347615707811607 0.7378049515764855 1.0 1.0 3 P02545 1 +Sparse scalp hair 0.2484621549242314 0.3343599988899739 0.7381079203540555 1.0 1.0 39 P18074,Q96GM5,Q71SY5,O14802,O60832,Q969G3,P62304,Q9NPE3,Q8TAQ2,P02545,Q92785,Q12824,Q9H2P0,O14497,P46778,Q96L73 16 +Ventricular escape rhythm 0.4314977732415908 0.3341094415868406 0.7382969757118039 1.0 1.0 5 P02545 1 +Prominent metopic ridge 0.3124099570176182 0.3339820322719669 0.7383931171311053 1.0 1.0 13 P46821,Q96GM5,O75845,Q00839 4 +Hyperreflexia in upper limbs 0.339659303860281 0.333801339501402 0.7385294725711369 1.0 1.0 9 O75298,P10809,P31040 3 +Decreased circulating gonadotropin concentration 0.4312273547336482 0.3332253499175018 0.7389641840902095 1.0 1.0 5 Q99496,Q969G3 2 +Colitis 0.3257806023763406 0.3327986721970079 0.7392862605970398 1.0 1.0 11 P50851,O43318,Q6PGP7,P49327,P49748,Q13043,P42224,Q15477,Q05655,Q15833 10 +Abnormal fear anxiety related behavior 0.2577014596987181 0.3321248294886164 0.7397950020497157 1.0 1.0 121 Q9UQN3,O60885,P55011,P51608,P54098,Q7Z6Z7,Q9UIG0,P40818,Q15233,Q9P2D1,O75175,Q12830,Q8NFV4,P19022,P25490,Q14203,Q9UQE7,Q9BPU6,Q15056,P08397,Q9HCK8,Q01082,Q9H2P0,Q6ZRS2,Q96L73,P11166,P43243,P55072,O60828,Q8N3R9,Q14683 31 +Amyotrophic lateral sclerosis 0.293330355440844 0.3315370396918016 0.7402388677969183 1.0 1.0 15 P43243,Q14203,Q9UQN3 3 +Abnormality of bone marrow cell morphology 0.2386235398543424 0.3306591587602187 0.74090195506946 1.0 1.0 57 O60832,P00374,Q14739,P11586,O60934,Q9Y2V7,P61011,P06748,P61254,Q92925,Q9NPE3,Q14980,Q9UJV9,Q9Y2R9,Q9H078,Q5F1R6,P62263,Q01130,P22314,Q05655,Q6UN15 21 +Type ii diabetes mellitus 0.2454370834788349 0.3286173683976217 0.7424449184675059 1.0 1.0 43 Q9Y6M1,O43837,O43709,O14802,O43395,Q8NFV4,Q15056,P02545,P54132,Q9UIG0 10 +Impaired social interactions 0.2374800292716664 0.3260807616354598 0.7443632522166963 1.0 1.0 51 P11166,Q14683,P51608,Q8TB37,O75380,Q8N183,Q96N67,Q01082,Q9BU61,Q9H2P0,Q9GZZ9,Q9GZY8,O94992 13 +Hypercalcemia 0.2797877778174096 0.3259317997797135 0.744475955535695 1.0 1.0 21 P31040,O43709,Q6P1J9,Q8NFV4,Q15056,P36957,O00443,Q9UIG0,Q96L73 9 +Erectile dysfunction 0.328810844311062 0.3259234093757732 0.7444823038093489 1.0 1.0 10 Q9P2D1,Q99496,Q969G3,P20700,Q06787 5 +Impotence 0.328810844311062 0.3259234093757732 0.7444823038093489 1.0 1.0 10 Q9P2D1,Q99496,Q969G3,P20700,Q06787 5 +Abnormality of the septum pellucidum 0.2410497065291936 0.3248413717188232 0.7453011309626869 1.0 1.0 47 Q13409,Q15910,P55011,P15311,O14974,Q6PJT7,Q96L73 7 +Ectropion 0.3233728690557589 0.3221579430117205 0.7473330439543053 1.0 1.0 11 Q99496,O14802 2 +Long eyelashes 0.2467185499711232 0.3209241516885712 0.7482678708296153 1.0 1.0 39 Q9UQE7,Q14683,O60885,Q8TAQ2,Q969G3,Q99496,Q04721,Q96N67,P26640,Q12824,Q92974,Q13724,O94979,Q6ZRS2,O94992 15 +Curly hair 0.3230253027019339 0.3206343325252222 0.748487516605024 1.0 1.0 11 P42345,P18583 2 +Deviation of the hand or of fingers of the hand 0.256623083726578 0.3199255565209372 0.7490247639275562 1.0 1.0 121 Q96ST3,Q9UBM7,Q8TD16,O60885,P51608,Q03252,Q9UIG0,Q15233,Q9P2D1,O75147,O75175,Q9Y448,O43709,Q12830,Q8NFV4,Q5JRA6,Q9NW13,Q15910,Q9UQE7,Q9BPU6,Q15056,P02545,O75369,P54132,Q15042,Q6ZRS2,Q9Y366,O60828,P21333,Q14683 30 +Oculomotor nerve palsy 0.3905321129505289 0.3193342444113838 0.7494730676612997 1.0 1.0 6 Q99496,Q969G3,Q15149 3 +Aplasia hypoplasia of the retina 0.5622077564148267 0.3184019374888918 0.7501800687894344 1.0 1.0 3 P26367 1 +Secondary microcephaly 0.2224132458188243 0.3182489288388842 0.7502961206960181 1.0 1.0 83 P11166,Q9UQE7,Q96T60,P00374,P51608,P36543,O14974,Q8TDP1,Q9Y2V7,Q9BSJ2,Q13813,Q96KP1,Q6P1N0,Q9GZZ9,Q9GZY8,Q14683 16 +Neoplasm of the respiratory system 0.2862998267527933 0.3182442874308279 0.7502996411359983 1.0 1.0 18 Q99496,Q01844,Q96L73 3 +Delayed social development 0.5618919771524078 0.3175651252528181 0.7508148317086927 1.0 1.0 3 Q9Y2V7 1 +Fatigable weakness of bulbar muscles 0.2892661224639377 0.3162230745150521 0.7518331947635666 1.0 1.0 16 P43243,Q14203,Q9UQN3 3 +Motor deterioration 0.3893190900340558 0.3151236960529342 0.7526677375582242 1.0 1.0 6 P51608 1 +Kyphoscoliosis 0.2359463189825752 0.3128562474620828 0.7543898795044783 1.0 1.0 61 P36543,P51608,Q96AY3,P18583,O15347,Q15233,Q04721,O14974,Q9NW13,P10412,P02545,Q14807,Q15042,Q12904,Q6ZRS2,Q96T60,O14802,P22314,P21333,O94992 20 +Abnormal morphology of the limbic system 0.3212071049680942 0.3127157014276261 0.7544966654366057 1.0 1.0 11 Q9BPU6,Q96JM3 2 +Absence of pubertal development 0.4246406137982347 0.3120080758245434 0.7550343858774435 1.0 1.0 5 Q9P2D1 1 +Abnormality of the ureter 0.2187478686911462 0.3105605371484908 0.7561347314178195 1.0 1.0 80 Q9UBM7,O60885,P62913,Q9UIG0,O15078,Q9P2D1,O43709,Q12830,Q8NFV4,P25490,Q9UQE7,Q15056,P02545,Q15149,Q96T60,Q96L73,O14802,P21333,Q14683 19 +Soft tissue sarcoma 0.2496754040986469 0.3102864619320754 0.756343125278716 1.0 1.0 34 O60934,Q969G3,Q6P1J9,Q99496,Q96JJ3,Q15437,Q01082,Q12824,Q9BZE9,P21333,Q05655 11 +Joint laxity 0.2246013145991239 0.3094957441202449 0.7569444490626316 1.0 1.0 86 Q96ST3,P36543,Q96AY3,Q92785,Q32P28,Q9UIG0,Q02809,Q15233,Q9P2D1,Q7Z3K3,O43709,Q969G3,Q04721,Q8NFV4,Q8WXI9,P50454,P25490,Q15056,Q14807,O75369,Q01082,Q9H2P0,Q6ZRS2,Q96L73,P21333 25 +Developmental cataract 0.2363023271437968 0.3093424337493159 0.7570610553266737 1.0 1.0 57 Q71SY5,P61254,O94979,P62847,P17980,P62913,P62273,P02545,P62081,P62899,P46777,P62857,P39019,Q15042,P61353,Q9UN37 16 +Abnormality of the musculature of the upper arm 0.3872042496936954 0.3078409321190154 0.7582033736829414 1.0 1.0 6 P02545 1 +Proximal upper limb amyotrophy 0.3872042496936954 0.3078409321190154 0.7582033736829414 1.0 1.0 6 P02545 1 +Aplasia hypoplasia of the eyebrow 0.2388818444458422 0.3067581948117179 0.7590274307219746 1.0 1.0 47 Q5F1R6,Q9P2D1,O14802,P18583,P02545,Q9Y2V7,P62857,O60828,Q6UX04 9 +Abnormality of the female genitalia 0.2724723546562697 0.3066466360794979 0.7591123521675645 1.0 1.0 144 Q9UBM7,O60885,O60832,P54098,Q15437,P20585,Q13049,Q9NQ48,P48735,Q9UIG0,O15078,P40818,Q03252,Q9P2D1,O60934,Q8NFV4,O14974,Q92878,Q01844,P06748,Q9UQE7,Q9NPE3,Q15056,P02545,P54132,O75874,Q15042,Q15051,Q13428,Q8NCM8,Q14683 31 +Ectopic kidney 0.2872650050158542 0.3061262682197463 0.7595085082543607 1.0 1.0 16 Q9Y448,Q8NFV4,Q15056,Q9UIG0 4 +Abnormal nasolacrimal system morphology 0.2869078566502674 0.3043399012617632 0.7608689491480076 1.0 1.0 16 Q9Y448,Q13428,Q9UQE7,P25490 4 +Bird like facies 0.386015522727987 0.3037801127946716 0.7612954188674415 1.0 1.0 6 Q92878 1 +Abnormality of the upper arm 0.2724301559469314 0.3023842691697221 0.7623591451961116 1.0 1.0 22 Q15910,O14802,O75369,P21333,Q6ZRS2 5 +Hemifacial spasm 0.4210152276762968 0.3005953427398431 0.76372308326543 1.0 1.0 5 Q99496,Q969G3 2 +Persistent ebv viremia 0.5552798456024224 0.3002858125357081 0.7639591541340802 1.0 1.0 3 Q05655,O95394 2 +Abnormal c reactive protein level 0.4205542725382947 0.2991580371974096 0.7648194653708908 1.0 1.0 5 Q9UBC1,P22314 2 +Type 1 muscle fiber atrophy 0.3619366169825083 0.2991118080676714 0.7648547369639058 1.0 1.0 7 P02545 1 +Abnormal clavicle morphology 0.2750007593406998 0.2988491355699082 0.7650551583306531 1.0 1.0 21 Q96AY3,O75369,P21333,Q8NCM8,Q6ZRS2 5 +Neuronal loss in basal ganglia 0.4203387313075037 0.2984870330821852 0.7653314714234845 1.0 1.0 5 Q9BU61,O95169 2 +Increased connective tissue 0.3387649481412521 0.296940109058292 0.7665122338213988 1.0 1.0 8 P02545,O14802 2 +High anterior hairline 0.2640765843854756 0.2969380782093903 0.7665137843193195 1.0 1.0 24 Q9H2P0,O75179,Q96L73,Q6UX04 4 +Abnormality of the musculature of the lower limbs 0.2501961552173589 0.2968952502156693 0.766546482545861 1.0 1.0 29 P43243,Q14331,P02545,Q14315,Q13049,Q15149 6 +Abnormal preputium morphology 0.3386125854486478 0.2963578454806867 0.7669568145051839 1.0 1.0 8 O60828,Q96L73 2 +Brachycephaly 0.2271945688959691 0.2959090630597032 0.7672995295445468 1.0 1.0 72 Q7Z3K3,Q13428,Q9UQE7,O60885,P51610,P51608,P24928,Q96AY3,Q9BPU6,Q9BZI7,Q9H2P0,Q7Z6Z7,O75179,O60828,Q15042,Q14683 16 +Slender build 0.3041365783120193 0.295791542562857 0.7673892822082085 1.0 1.0 13 Q9BZI7,P54098,O14802 3 +Plagiocephaly 0.2447694888097945 0.2955134426218591 0.7676016849069667 1.0 1.0 37 Q9UQE7,P24928,Q9BPU6,Q9Y2W2,Q8TDP1,Q01082,Q9H2P0,Q15233 8 +Coronary artery atherosclerosis 0.4191393643345258 0.2947658302717198 0.7681727707399126 1.0 1.0 5 P02545,Q8N1G0,P34913 3 +Short chin 0.321288336649391 0.2942970320619432 0.7685309403611531 1.0 1.0 10 P02545,P21333 2 +Intrinsic hand muscle atrophy 0.5523752381759999 0.2928437978693641 0.7696415491494739 1.0 1.0 3 Q14315 1 +Abnormal cardiac atrium morphology 0.2825951137228353 0.2922290431003005 0.7701115071325961 1.0 1.0 162 Q9UBM7,O60885,P36543,P53597,P62913,P18583,Q92785,Q9UIG0,O15078,Q15233,Q9P2D1,O43709,Q04721,Q8NFV4,Q13043,P98175,Q9Y2V7,P25490,P13807,P11274,Q9UQE7,P61254,Q15056,P62273,O60826,P62081,O75369,P62899,P62857,P02545,P39019,P46777,Q6ZRS2,Q96L73,P29401,O14678,Q9BZI7,Q14315,O60828,Q14683 40 +Palpitations 0.2790093334702079 0.2918210460885149 0.7704234528462583 1.0 1.0 19 Q9UER7,P31040,Q7LG56,P19022,P54098,P36957,P25490 7 +Aplasia hypoplasia of the lungs 0.2459721737744934 0.2899560799333038 0.7718498379471264 1.0 1.0 35 P18583,P02545,P98175,O75369,P21333,Q8NCM8,Q92917 7 +Open mouth 0.2478100046647484 0.2881340758472985 0.7732441094148457 1.0 1.0 32 Q96ST3,Q7Z3K3,P42345,Q96JM3,Q96DF8,Q15233 6 +Lower extremity joint dislocation 0.2215676059158267 0.2864196304219036 0.7745567413087442 1.0 1.0 85 Q9Y281,P46821,Q9UBM7,Q8TD16,O60885,P55011,P36543,Q6ZXV5,Q9UIG0,O75147,O43709,Q04721,Q8NFV4,Q9UQE7,Q9BPU6,Q15056,Q14807,P02545,O75369,Q5F1R6,P21333,Q14683 22 +Absent hair 0.314981376425114 0.2862735998492571 0.774668576631417 1.0 1.0 11 Q13428,Q6UX04 2 +Gastrointestinal hemorrhage 0.2452539952639469 0.2849428031749255 0.775687962466374 1.0 1.0 35 P49257,Q9UER7,Q8NBM4 3 +Abnormal ventricular septum morphology 0.2823024434619464 0.2827575874164651 0.7773626683645791 1.0 1.0 163 Q9UBM7,Q8NC56,Q96GM5,P31040,O60885,P55011,P18583,Q14739,Q14839,P62913,Q8N183,Q92785,Q12824,Q9UIG0,O15078,O00192,Q15233,Q6UX04,Q9P2D1,Q71SY5,P36776,O43709,Q969G3,Q04721,Q8NFV4,Q2VPK5,Q9Y2V7,Q96KP1,Q15477,O14497,P11274,Q9UQE7,P61254,Q15056,P62273,O60826,P62081,O75369,P62899,Q7LBC6,Q01082,P62857,P39019,P46777,O75251,P61353,O94979,O75489,Q96L73,P0DP25,P47985,Q96T60,P29401,Q8TAQ2,Q9Y2W2,Q96DF8,Q15031,O60828,P62847,Q14683 60 +Mild hearing impairment 0.3091048718209788 0.2818343680661826 0.7780705167746451 1.0 1.0 12 P51610,P51608 2 +Aplasia hypoplasia involving the sinuses 0.3794269331551582 0.2817088683774152 0.7781667538135104 1.0 1.0 6 P21333 1 +External ophthalmoplegia 0.2686631143492894 0.2811565127213062 0.7785903576198341 1.0 1.0 22 P54098,Q8N183,Q14331,Q9GZY8 4 +Abnormality of the metopic suture 0.2830615302555209 0.2811019351153765 0.7786322169819244 1.0 1.0 15 P46821,Q96GM5,P18583,O75845,Q00839 5 +Acute coronary syndrome 0.2686118597800091 0.2808724939135941 0.7788081984216313 1.0 1.0 22 Q8NBM4,Q8NFV4,Q15056,P02545,P35579,Q9UIG0 6 +Vascular neoplasm 0.2425378666048137 0.2796049622402811 0.7797805995834852 1.0 1.0 37 P42345,O60826,Q15437,O75874,P48735,Q96L73 6 +Optic nerve hypoplasia 0.2741790045553881 0.2793119031419753 0.7800054722747876 1.0 1.0 20 Q9Y448,Q8WXI9 2 +Supravalvular aortic stenosis 0.3340219758954683 0.2790623221916822 0.7801969974447203 1.0 1.0 8 Q8NFV4,Q15056,Q9UIG0 3 +Hypsarrhythmia 0.2305724672012302 0.2780947697661836 0.7809396105713984 1.0 1.0 65 Q71SY5,Q96T60,Q12904,P55011,P51610,P15311,O95319,Q96N67,Q9NVC6,Q13813,Q01082,Q6PJT7,Q6P1N0,Q9GZZ9,Q9GZY8,Q14683 16 +Arm dystonia 0.447764172360955 0.2778743687145997 0.7811088001382502 1.0 1.0 4 P35637,Q9H269 2 +Chronic constipation 0.252235577053355 0.2777029295153721 0.7812404115933231 1.0 1.0 26 P55011,P51608,Q8WXI9,Q9H2P0,Q03252 5 +Proximal muscle weakness 0.2305122763113425 0.2775352623573078 0.7813691333664023 1.0 1.0 65 Q9Y281,Q8TD16,O75190,P11047,P08397,Q7Z406,P02545,P54098,Q14315,Q13049,Q15149 11 +Toxemia of pregnancy 0.3781153009986121 0.2774048200225923 0.7814692809650585 1.0 1.0 6 P02545,P22570,O43772,Q01082 4 +Abnormality of immune serum protein physiology 0.3256006628003371 0.2773705841609296 0.7814955662785279 1.0 1.0 9 P49327,Q8TDP1,O75792,P42224,Q9Y3Z3,Q05655,P55265,Q15833 8 +Tics 0.3332553927310385 0.2762214515187596 0.7823779820060817 1.0 1.0 8 Q8WXI9,Q01082 2 +Vertebral compression fracture 0.2779807265406157 0.2754554228414922 0.7829663689561328 1.0 1.0 18 Q5F1R6,Q96AY3,P40818 3 +Paraganglioma 0.3329257092912466 0.2750038949790391 0.7833132458827665 1.0 1.0 8 Q9UER7,P36957 2 +Pigmentary retinopathy 0.232369795135426 0.2745507466940853 0.7836614109725435 1.0 1.0 57 Q13049,Q8N183,O15078 3 +Pseudoarthrosis 0.5449319219737764 0.2741962046092984 0.783933844676227 1.0 1.0 3 Q9NWH9 1 +Right ventricular hypertrophy 0.3768391399522142 0.2732463053912809 0.784663887242588 1.0 1.0 6 P11047 1 +Homocystinuria 0.445948798305233 0.2728239865925349 0.7849885201476654 1.0 1.0 4 O14678 1 +Facial asymmetry 0.2424697303324584 0.2720026356558817 0.7856199927676011 1.0 1.0 36 Q96ST3,Q9P2D1,P11274,Q9UQE7,Q14683,Q96JJ3,P18583,P21333,P25490 9 +Meningocele 0.2987220688019191 0.2719432429470922 0.7856656606600407 1.0 1.0 13 P21333,O15078 2 +Female hypogonadism 0.4113609384568717 0.2711577038413965 0.7862697421069131 1.0 1.0 5 Q9P2D1 1 +Open operculum 0.5341786108048385 0.2706435497862698 0.7866651975024987 1.0 1.0 2 P07954 1 +Abnormal circulating follicle stimulating hormone concentration 0.3534223575149249 0.2692896763043931 0.7877067759706118 1.0 1.0 7 Q8IY37,Q99496,Q969G3,P51809 4 +Paroxysmal involuntary eye movements 0.263025557019786 0.2688105115410761 0.7880755039443921 1.0 1.0 23 O75380 1 +Intellectual disability progressive 0.2797254400111426 0.2655543932471992 0.7905824136063806 1.0 1.0 15 P51608,Q6P1N0 2 +Abdominal obesity 0.3521040087174748 0.2648028280830782 0.7911613581510437 1.0 1.0 7 P40818,P54132 2 +Aortic root aneurysm 0.2453742895540781 0.2647212254274523 0.7912242251261372 1.0 1.0 27 O75175,P55011,Q12830,Q9BPU6,P02545,Q7Z6Z7,Q14697,Q8N3R9,P31153 9 +Abnormality of dental structure 0.216618147449125 0.2646423750224505 0.7912849730477307 1.0 1.0 82 Q9UBM7,O60832,P55011,P36543,Q96AY3,Q9UIG0,O75147,O43709,Q8NFV4,P50454,Q9Y2V7,Q9NW13,P06748,Q9NPE3,Q15056,P02545,O75369,Q15149,Q6ZRS2,Q5F1R6,Q13428,Q9Y366 22 +Dry hair 0.5406850503260874 0.2638343808916233 0.791907540796964 1.0 1.0 3 O60828 1 +Spinal rigidity 0.2965092443274181 0.2624681950422874 0.7929605027287758 1.0 1.0 13 Q9Y281,P02545,Q5JTV8 3 +Spastic paraplegia 0.230591008737496 0.2597680164132312 0.7950427234142488 1.0 1.0 58 P11166,P51608,Q8N183,Q9BRK0,P40818,P07942 6 +Tachypnea 0.2571975608721012 0.256879213627127 0.7972720173915486 1.0 1.0 24 O14678,P51608,O15078 3 +Pleural effusion 0.3024399743789361 0.2542018962377267 0.7993395857272263 1.0 1.0 12 Q13043,Q99496,Q8NBM4,Q14739 4 +Back pain 0.2434142908408737 0.2525240048929928 0.800636061965623 1.0 1.0 27 P42771,P14314,Q01082,Q969G3,Q99496,P08397,P02545,P50336,Q8WX93,Q12824,P55072,P50402 12 +Dental malocclusion 0.2523604159782507 0.2521158055815172 0.8009515534015628 1.0 1.0 25 O75147,O43709,Q8NFV4,Q15056,P21333,Q9UIG0 6 +Preaxial hand polydactyly 0.2939042289346657 0.2515203746187433 0.8014118117269624 1.0 1.0 13 O15078 1 +Carious teeth 0.2280847841401385 0.250260576702641 0.8023858417942169 1.0 1.0 50 P06748,Q5F1R6,O60832,Q9NPE3,P36543,Q8NFV4,Q15056,Q9Y366,Q9Y2V7,Q9NW13,Q15149,Q9UIG0,Q6ZRS2 13 +Abnormality of the testis size 0.2407869238948325 0.2496483582935945 0.8028592978547693 1.0 1.0 34 Q9P2D1,O60832,P51608,P38159,Q9BZI7,Q13620,Q9H7N4,Q8IY37,O60828,P51809 10 +Platybasia 0.3474496327957827 0.2492505695338966 0.8031669646099426 1.0 1.0 7 Q04721,O75369 2 +Contractures involving the joints of the feet 0.2651649834115028 0.2465733958441319 0.8052383959483846 1.0 1.0 21 Q8TD16,P02545,P21333,Q15149,P50402 5 +Abnormality of corneal size 0.2301093963443475 0.2463715301019935 0.8053946428004775 1.0 1.0 48 Q71SY5,Q9UQE7,Q14683,O60885,O43709,O75845,Q8NFV4,Q15056,O15347,Q15042,Q9UIG0,O15078,Q02809 13 +Decreased proportion of cd4 positive helper t cells 0.3232789331482805 0.240523487728009 0.8099244570328277 1.0 1.0 8 Q13432,Q9Y448 2 +Single fiber emg abnormality 0.5296388199613965 0.2378528306435375 0.8119952413249758 1.0 1.0 3 Q06210,O75340 2 +Muscle fiber tubular inclusions 0.5296388199613965 0.2378528306435375 0.8119952413249758 1.0 1.0 3 Q06210,O75340 2 +Abnormality of the hypothenar eminence 0.4325774152023321 0.2370305051766503 0.8126331247898646 1.0 1.0 4 P62913 1 +Patent ductus arteriosus 0.22819782895538 0.2361964106039651 0.8132802646564221 1.0 1.0 97 P46821,Q9UBM7,Q96GM5,P53597,P62913,P18583,Q92785,Q12824,O15160,Q6ZXV5,Q9UIG0,O00192,Q15233,Q9P2D1,O43709,Q969G3,Q04721,Q8NFV4,Q12830,Q2VPK5,Q9Y2V7,Q15477,O14497,Q9UQE7,Q15056,O60826,P02545,P46777,P0DP25,P31153,Q96L73,P29401,Q13428,Q8TAQ2,Q15031,P21333,Q15650 37 +Aganglionic megacolon 0.2570010063844199 0.2361465290755181 0.8133189697391674 1.0 1.0 23 O15078 1 +Severe global developmental delay 0.2143766153792551 0.2339824855097408 0.8149985758272711 1.0 1.0 78 Q13409,Q14683,P55011,P51608,Q12830,Q8N201,Q9BPU6,Q99496,Q8TDP1,Q8N3R9,Q7Z6Z7,Q96KP1,Q9H2P0,P07942,Q9UN37,P25490 16 +Gastritis 0.3634105960264963 0.23128095913264 0.8170965381239399 1.0 1.0 6 P50851,Q05655,Q13546,Q15477,P49327 5 +Zonular cataract 0.2888896355113207 0.2310879270991122 0.8172464940874622 1.0 1.0 13 Q9H444,P11166 2 +Abnormal erythrocyte sedimentation rate 0.3204684980393462 0.2309051752551779 0.8173884701019416 1.0 1.0 8 Q9UBC1,Q05655,P22314 3 +Increased adipose tissue 0.4297384356073682 0.2297573154877868 0.8182803547176705 1.0 1.0 4 O14802 1 +Abnormality of the musculature of the thigh 0.3196315778153529 0.2280790307094577 0.8195848015631937 1.0 1.0 8 P02545 1 +Eeg with focal epileptiform discharges 0.2323271856871207 0.2264315253555049 0.8208658108807385 1.0 1.0 42 Q71SY5,P11166,P55011,P51608,Q96N66,P15311,Q96N67,Q01082,Q6PJT7,Q6P1N0,Q12904,Q96T60 12 +Short ribs 0.2995009186321214 0.2252925785393094 0.8217516727473979 1.0 1.0 11 Q8NCM8,Q15910 2 +Tachycardia 0.243159296609192 0.2239196180043144 0.8228198503334889 1.0 1.0 26 P08397,P19022,O43772,P02545 4 +Morphological abnormality of the pyramidal tract 0.2472860673405796 0.2236747729627664 0.8230103768881873 1.0 1.0 25 Q14203,P11166,O75298,Q8NFV4,Q15056,P55072,Q9UIG0 7 +Upper limb muscle weakness 0.2385839955595407 0.2232332941428936 0.8233539406893464 1.0 1.0 28 O14908,Q969G3,Q99496,Q92734,P08397,P02545,Q8N0X7,P50570,P50336,P55072,Q12824,P50402,Q02809 13 +Focal white matter lesions 0.3104502139434472 0.2220805154506397 0.8242512055632887 1.0 1.0 9 P42345,P54098,Q9H2P0 3 +Frontotemporal dementia 0.310246623540354 0.2213788773734641 0.8247974378453053 1.0 1.0 9 Q14203,Q9UQN3 2 +Absence of subcutaneous fat 0.3597936808614663 0.220554808734202 0.8254390918815544 1.0 1.0 6 O14802 1 +Abnormal temper tantrums 0.3173501895964269 0.2204647710220672 0.825509206055494 1.0 1.0 8 Q9H2P0,Q6ZRS2,Q9BVA1 3 +Increased sensitivity to ionizing radiation 0.3597005451514621 0.2202819285903923 0.8256515934099735 1.0 1.0 6 Q12824,Q99496,Q969G3 3 +Subglottic stenosis 0.5204597506046535 0.2173550766049141 0.827931637947374 1.0 1.0 3 P21333 1 +Sparse eyebrow 0.2340657825145818 0.2169858772198431 0.8282193510956855 1.0 1.0 36 O14802,P18583,P02545,Q9Y2V7,P62857,O60828,Q6UX04 7 +Abnormal tricuspid valve morphology 0.2772039516482733 0.216941757439068 0.8282537347134717 1.0 1.0 14 O60826,P21333,Q15233 3 +Chronic kidney disease 0.2320318695636224 0.2165938958432211 0.8285248432338161 1.0 1.0 38 Q15051,Q9Y5K6,P11047,O15078 4 +Abnormal fingernail morphology 0.2251025946632403 0.2162343222298974 0.8288051010722448 1.0 1.0 55 P06748,Q15910,O43709,O60832,Q9NPE3,Q8NFV4,Q15056,Q9Y366,P02545,O60826,Q92785,Q15149,Q9UIG0,Q96L73 14 +Narrow nose 0.358228271265819 0.215990578204086 0.8289950917391709 1.0 1.0 6 Q9Y4L1 1 +Abnormal endocrine physiology 0.3911496168954119 0.2142788812137505 0.8303295859147961 1.0 1.0 5 P50336,Q9NW13 2 +Abnormal myeloid leukocyte morphology 0.2311932223840672 0.2123254591965741 0.8318531346423148 1.0 1.0 103 Q9Y3C6,Q9NRZ9,P31040,O60832,Q05655,Q14739,P62913,P26038,Q9Y4L1,P18206,Q9P2D1,Q13043,P61011,O00165,P06748,P11274,P54819,P61254,Q92925,Q9NPE3,Q14980,Q7Z2Z2,P62273,Q9UJV9,P02545,P62081,Q9H078,P62899,P62857,P46777,P39019,Q14126,P35579,P61353,Q5F1R6,P42167,P01889,P62263,O14678,Q01130,P62847,Q6UN15 42 +Abnormal social behavior 0.2192191944515766 0.2112079194193114 0.8327250313418202 1.0 1.0 71 Q9Y3C6,P51608,O75380,Q8N183,Q96N67,Q9UIG0,Q15233,O43709,Q8NFV4,Q9Y2V7,Q9BU61,Q8TB37,Q15056,Q01082,Q9H2P0,Q9GZZ9,Q9GZY8,P11166,O94992,Q14683 20 +Nausea 0.2619679333286889 0.209325273017962 0.8341943237541831 1.0 1.0 19 P31040,Q01130,P08397,P54098,P50336,P36957,P38117 7 +Cerebral hypoplasia 0.2661870503597112 0.2093157027278919 0.8342017942743392 1.0 1.0 16 P07954,Q96SN8,Q96C36,Q9UBM7,P51659,P42695,Q00534,Q13057,O60566,O43175,O60762,P35606,P22570,Q92947,Q5MNZ6 15 +Decreased testicular size 0.2445243709828789 0.2088665796653864 0.8345523942903477 1.0 1.0 25 Q9P2D1,O60832,Q13620,Q9H7N4,Q8IY37,O60828,P51809 7 +Ureterocele 0.388491697118248 0.2072998851278383 0.8357756638531291 1.0 1.0 5 Q96T60 1 +Abnormal male reproductive system physiology 0.2300290394174824 0.206245253859679 0.8365993401681922 1.0 1.0 40 Q9P2D1,O43709,O75298,Q969G3,P51608,Q99496,Q8NFV4,Q15056,Q06787,P54132,Q14697,Q8IY37,Q12824,P20700,Q9UIG0,P51809 16 +Barrett esophagus 0.5151988985431005 0.2060638723691053 0.8367410187934166 1.0 1.0 3 P07954 1 +Intellectual disability borderline 0.507166482910681 0.2052062453122447 0.8374109902227045 1.0 1.0 2 Q7Z392 1 +Edema of the dorsum of feet 0.5066152149944737 0.2039772283972316 0.8383712939051917 1.0 1.0 2 Q9Y263 1 +Edema of the dorsum of hands 0.5066152149944737 0.2039772283972316 0.8383712939051917 1.0 1.0 2 Q9Y263 1 +Flat acetabular roof 0.3540058280301778 0.2039174613419806 0.8384179995943646 1.0 1.0 6 Q9Y366 1 +Split nail 0.4183448542703628 0.2017562213905213 0.8401073079315504 1.0 1.0 4 O60832 1 +Metaphyseal irregularity 0.2918792827096141 0.1979186079123457 0.8431087451459405 1.0 1.0 11 Q5F1R6,Q7Z2Z2,Q9NR45,Q14807,P61011,P26373 6 +Abnormal oral mucosa morphology 0.2217610414367112 0.1979146090997854 0.8431118738554195 1.0 1.0 64 Q9UBM7,O60832,O75845,Q9UIG0,Q9Y4L1,O43709,Q02241,Q04721,Q8NFV4,Q8NBM4,Q5JRA6,P06748,P49257,Q9NPE3,Q14980,Q15056,Q15149,Q5F1R6,Q96JJ3,Q6UN15 20 +Abnormal platelet morphology 0.3515617653894108 0.1970896407665291 0.8437573899071431 1.0 1.0 6 O75845,P12814,Q86YV9 3 +Proximal tubulopathy 0.2338185642160967 0.1969042437850893 0.843902472635484 1.0 1.0 30 Q8N183,O75380 2 +Abnormal cell morphology 0.350871993781449 0.1951841375887496 0.8452487966111932 1.0 1.0 6 Q6NZY4,Q7LG56,P54098 3 +Impaired vibration sensation in the lower limbs 0.2603665641037733 0.1947373645409077 0.8455985591748973 1.0 1.0 18 Q9BRK0,O14802 2 +Functional abnormality of male internal genitalia 0.2331805063909166 0.1946369401040026 0.8456771820490163 1.0 1.0 31 Q9P2D1,O43709,P51608,Q8NFV4,Q15056,P54132,Q14697,Q9UIG0,P51809 9 +Severe cytomegalovirus infection 0.5022050716648153 0.1943017409123687 0.8459396225616111 1.0 1.0 2 Q9H0U3 1 +Myositis 0.2908282719116918 0.1942864843719128 0.845951567908725 1.0 1.0 11 Q8NBM4 1 +Eversion of lateral third of lower eyelids 0.5019294377067116 0.1937062942238848 0.846405863117158 1.0 1.0 2 P60953 1 +Hypolipidemia 0.5011025358324006 0.1919265157588421 0.8477997669674289 1.0 1.0 2 Q9Y6B6 1 +Hypotriglyceridemia 0.5011025358324006 0.1919265157588421 0.8477997669674289 1.0 1.0 2 Q9Y6B6 1 +Congenital malformation of the great arteries 0.2409122555102889 0.1917159712265851 0.8479646948224955 1.0 1.0 117 Q9UBM7,P53597,P62913,P18583,Q92785,Q6ZXV5,Q9UIG0,Q15233,Q9P2D1,O43709,Q04721,Q8NFV4,Q12830,P98175,Q9Y2V7,Q9UQE7,Q15056,O60826,P02545,P46777,Q6ZRS2,Q96L73,P29401,Q13428,Q96DF8,O60828,P21333 27 +Abnormal blood ion concentration 0.2143336128595626 0.1915481058135309 0.8480961952066182 1.0 1.0 74 Q9P2D1,Q15056,Q9NP58,P08397,Q96DF8,P40818,P35658,O14745,Q96L73 9 +Wormian bones 0.2593130178271808 0.1903591659800117 0.8490276933881926 1.0 1.0 18 Q8NC56,Q04721,Q96AY3,P02545,P21333 5 +Abnormal t cell subset distribution 0.2702064880903422 0.1898822265099752 0.8494014202760514 1.0 1.0 14 Q9Y448,P54132 2 +Increased sulfur amino acid level in urine 0.3485857051592245 0.1889362108862801 0.8501428124758768 1.0 1.0 6 O14678 1 +Aplasia hypoplasia involving the nose 0.232080848669843 0.1884942436691199 0.8504892275287805 1.0 1.0 31 Q96ST3,P11274,P02545,O75369,Q96DF8,Q15149,Q6UX04 7 +Abnormal vagina morphology 0.2551604945111108 0.1882021178926708 0.850718212317402 1.0 1.0 20 Q13428,O14974 2 +Extrapyramidal dyskinesia 0.5060870810686482 0.1873080802491534 0.8514190879855446 1.0 1.0 3 P11166 1 +Abnormality of refraction 0.2760992661883679 0.1869858597324933 0.8516717197102006 1.0 1.0 169 Q96ST3,O60885,P55011,P36543,P18583,Q15437,Q7Z6Z7,Q92785,Q9HD42,Q92974,Q9UIG0,Q15233,Q7Z3K3,O75175,P30533,O43709,Q12830,Q8NFV4,Q8WXI9,O14974,Q96JM3,P98175,Q92878,P25490,P10412,Q9UQE7,Q99496,Q9BPU6,P11047,Q15056,Q9H2P0,Q9H3H1,Q6ZRS2,Q96L73,Q5F1R6,O14802,Q8N201,Q9Y366,O60828,P21333,Q8N3R9,Q14683 42 +Gastrointestinal obstruction 0.2603006004447192 0.1855921819700269 0.8527645849359331 1.0 1.0 16 P42771,P31040,P08397,P50336,Q8WX93,Q01844 6 +Restrictive cardiomyopathy 0.4980705622932605 0.1854850174319801 0.8528486307245584 1.0 1.0 2 O95235 1 +Abnormal finger phalanx morphology 0.2860528866868074 0.1853088222730549 0.8529868186967158 1.0 1.0 189 Q9UBM7,O60885,P55011,P51608,P62913,Q7Z6Z7,Q13049,Q9UBC1,Q9NQ48,O15078,Q6UX04,Q15233,Q9P2D1,Q9Y448,O75175,P02545,Q04721,Q12830,Q8WXI9,P98175,Q5JRA6,P46777,Q15910,P11274,Q9UQE7,P61254,Q9BPU6,P62273,Q14807,P62081,O60826,P62899,P54132,Q01082,O75369,P62857,P39019,Q15042,P61353,Q9H2P0,Q92917,Q96L73,Q6ZRS2,O14802,P42345,P51610,Q9Y366,Q9BZI7,P82673,O60828,P21333,Q8NCM8,Q8N3R9,Q14683 54 +Enlarged kidney 0.3265566176379165 0.1852227283992367 0.8530543428391935 1.0 1.0 7 Q9UBS4,Q8NCM8,Q14697 3 +Increased serum pyruvate 0.2276083527960077 0.1836574555889476 0.8542821866152632 1.0 1.0 37 Q8N183,O75380 2 +Abnormal meningeal morphology 0.2355748083794564 0.1831143633886943 0.8547082859686492 1.0 1.0 26 P21333,P18583,O15078,Q14683 4 +Polycystic liver disease 0.4100177473959484 0.1825213737692695 0.8551735822376401 1.0 1.0 4 P14314 1 +Abnormal serum interferon level 0.3254209218879421 0.1820235905968626 0.8555642125398015 1.0 1.0 7 Q8TDP1,O75792,P42224,Q9Y3Z3,P55265,Q15833 6 +Rod cone dystrophy 0.222529805552819 0.1794070219383853 0.857618118131922 1.0 1.0 46 Q15051,O43395,Q9UGM6,O15078,Q6UX04 5 +Emphysema 0.2899377334767988 0.1791757563296387 0.8577996993099339 1.0 1.0 10 P18583,Q96L73 2 +Atrophy degeneration involving the spinal cord 0.3041741080484477 0.1791137350736796 0.857848397379577 1.0 1.0 8 P54098,Q13217,P20700 3 +Neoplasm of the male external genitalia 0.2818484714959622 0.1777287088799831 0.8589360377540454 1.0 1.0 12 Q8IY37,Q6P1J9,Q01844,P51809 4 +Temporal cortical atrophy 0.4078507644985999 0.1776892839714024 0.858967001474698 1.0 1.0 4 Q9UQN3 1 +Tibial bowing 0.4075698572997124 0.1770681812398951 0.8594548346638 1.0 1.0 4 P21333,O75369 2 +Short palpebral fissure 0.2297747365364265 0.1750033192342265 0.8610770254638616 1.0 1.0 27 P98175,Q7Z6Z7,Q12830,O14974 4 +Gait imbalance 0.2442370206730734 0.173681595564079 0.8621157022956953 1.0 1.0 23 Q8NFV4,Q15056,Q14315,P55072,Q9UIG0 5 +Abnormal circulating dehydroepiandrosterone concentration 0.4920066152149803 0.1730011561527474 0.8626505188478699 1.0 1.0 2 P04637 1 +Tooth malposition 0.2260869585346533 0.1728769065023998 0.8627481842666549 1.0 1.0 102 Q96ST3,Q9UBM7,O60885,P51608,P24928,P36543,O15347,Q96N67,Q9UIG0,Q15233,O75147,O43709,Q12830,Q8NFV4,Q8WXI9,Q9BSJ2,Q9UQE7,Q99496,Q15056,P02545,Q9H2P0,Q15042,Q13428,Q9Y366,Q9BZI7,P21333,Q14683 27 +Underdeveloped tragus 0.4914553472987729 0.171892727180134 0.8635218643539047 1.0 1.0 2 Q5SRE5 1 +Abnormal motor nerve conduction velocity 0.2489116592153834 0.1709072878828181 0.8642966660771627 1.0 1.0 21 P02545,Q5TAQ9,Q96T60 3 +Abnormal blood sodium concentration 0.2871025352465336 0.1701931490438234 0.864858239391302 1.0 1.0 10 P35658 1 +Pain in head and neck region 0.3009558547885061 0.1697090302905772 0.8652389719511526 1.0 1.0 8 P08397,Q99496,Q969G3 3 +Abnormal arterial physiology 0.2283078180282327 0.1681339306294807 0.8664779165172622 1.0 1.0 31 P78347,O43709,Q8NBM4,P18583,Q14739,Q8NFV4,Q15056,P31153,P02545,Q8TDP1,O00443,Q9UIG0,Q02809 13 +Phocomelia 0.4957264957264913 0.1672317725972016 0.8671876855079286 1.0 1.0 3 Q15427,Q9Y5S9 2 +Aplasia cutis congenita of scalp 0.3197848352203284 0.1665894843232176 0.8676930683673509 1.0 1.0 7 Q14692 1 +Sparse and thin eyebrow 0.2821943800488313 0.1657869880023372 0.8683245864821718 1.0 1.0 11 O14802 1 +Finger clinodactyly 0.2170952484805205 0.1654791953580008 0.8685668237778956 1.0 1.0 93 O60885,P51608,Q03252,Q9UIG0,Q15233,Q9P2D1,O75147,O75175,Q9Y448,O43709,Q12830,Q8NFV4,Q5JRA6,Q9UQE7,Q15056,P02545,O75369,P54132,Q6ZRS2,Q9Y366,O60828,Q14683 22 +Aplasia hypoplasia of the 4th metacarpal 0.4942373964645162 0.1644565270824736 0.869371767089334 1.0 1.0 3 P21333 1 +Abnormality of the 4th metacarpal 0.4942373964645162 0.1644565270824736 0.869371767089334 1.0 1.0 3 P21333 1 +Vocal cord paralysis 0.2525428516508531 0.1634825195138572 0.8701385353979134 1.0 1.0 18 Q14203,P31040,P43243,P02545,P36957,P50402 6 +Skeletal myopathy 0.3694410910957805 0.1608466170465905 0.8722142081262034 1.0 1.0 5 P55084 1 +Increased circulating gonadotropin level 0.2910714435093657 0.1604696886316821 0.8725110971492178 1.0 1.0 9 P82650,Q15031,Q8IY37,Q06787,P51809 5 +Abnormality of the tragus 0.4915908464295517 0.1595928184456005 0.8732018365202214 1.0 1.0 3 A6NHR9,Q5SRE5 2 +Aplasia hypoplasia of the tragus 0.4915908464295517 0.1595928184456005 0.8732018365202214 1.0 1.0 3 A6NHR9,Q5SRE5 2 +Hepatocellular carcinoma 0.2433439260846405 0.1577337911274269 0.87466657232557 1.0 1.0 22 Q9UDY2,Q9NWH9,Q13043,P08397,P50336,Q05655 6 +Keratitis 0.2685436156065769 0.1572751551518341 0.8750279998815738 1.0 1.0 13 P01889,Q8NBM4,Q14739,Q15149,P26367 5 +Lower limb hyperreflexia 0.2506193247787142 0.1562474029620145 0.8758380133794628 1.0 1.0 18 P31040,P51608,Q9Y4W6,P55072,P40818,Q15233 6 +Congenital hip dislocation 0.225898401538752 0.155419289318299 0.8764907782570077 1.0 1.0 27 Q8TD16,Q5F1R6,P21333 3 +High myopia 0.2820134348886013 0.1546933756650052 0.8770630525820786 1.0 1.0 10 P30533 1 +Epileptic encephalopathy 0.2258412005230643 0.1544211176331471 0.8772777039003721 1.0 1.0 28 Q05682,Q13813 2 +Functional abnormality of the middle ear 0.2204080142643751 0.1543874888769131 0.8773042178194712 1.0 1.0 98 O43837,O60885,P55011,Q7Z6Z7,O15160,Q9P2D1,O75175,Q04721,Q12830,Q15555,Q9UQE7,Q9BPU6,P02545,O75369,P62857,Q6ZRS2,Q96L73,Q13428,O43395,Q96JJ3,P21333,Q8N3R9,O75845,Q14683 24 +Abnormal neuron morphology 0.2258277433008297 0.1543548309594721 0.8773299664319283 1.0 1.0 28 P43243,O14802,Q9UQN3,Q9NW13 4 +Abnormal circulating hormone concentration 0.2139271480316642 0.1540248101251531 0.8775901733567841 1.0 1.0 91 Q96ST3,P31040,O43837,P51608,Q12824,Q8IY37,P40818,Q9UER7,Q9P2D1,Q969G3,Q6P1J9,Q15555,O75879,Q9NW13,P61011,P51809,P25490,Q99496,P02545,O75369,Q9H2P0,Q5F1R6,O43395,O14802,P82650,Q15031,P36957,Q06787,Q14683 29 +Abnormality of the ankles 0.2172215822865516 0.1516088364887197 0.8794954634693175 1.0 1.0 47 O43709,O75298,Q12830,Q96AY3,Q8NFV4,Q15056,P02545,Q5JTV8,Q9HD42,P21333,Q9UIG0,Q96L73,Q15233 13 +Peritoneal abscess 0.364965517241383 0.1508606211854455 0.8800856646294213 1.0 1.0 5 P42771,P04637,P38398,Q8WX93 4 +Ovarian carcinoma 0.364965517241383 0.1508606211854455 0.8800856646294213 1.0 1.0 5 P42771,P04637,P38398,Q8WX93 4 +Functional intestinal obstruction 0.364965517241383 0.1508606211854455 0.8800856646294213 1.0 1.0 5 P42771,P04637,P38398,Q8WX93 4 +Extrahepatic cholestasis 0.364965517241383 0.1508606211854455 0.8800856646294213 1.0 1.0 5 P42771,P04637,P38398,Q8WX93 4 +Cerebellar vermis atrophy 0.286937310135327 0.1487137272668849 0.8817795288999473 1.0 1.0 9 Q96S52,P47897,P07437,Q8WVX9,Q10713,Q13620,Q15334,Q96KG9 8 +Retinal perforation 0.4790518191841116 0.1481232274564245 0.88224551878388 1.0 1.0 2 P04439 1 +Epiretinal membrane 0.4790518191841116 0.1481232274564245 0.88224551878388 1.0 1.0 2 P04439 1 +Retinal fold 0.4790518191841088 0.1481232274564188 0.8822455187838845 1.0 1.0 2 P52732 1 +Increased proteinogenic amino acid level in urine 0.2651931542728795 0.1465696383112222 0.883471719934847 1.0 1.0 13 P23378,O14678 2 +Death in adulthood 0.2487545182625701 0.1456704155565308 0.884181577166439 1.0 1.0 17 Q9UIG0,Q8NFV4,Q15056,P54098,Q9UN37 5 +Abnormal cortical gyration 0.2572054945708011 0.1455135878669737 0.8843053883652137 1.0 1.0 146 P46821,Q96SN8,Q9Y3C6,Q96C36,Q96GM5,Q9BVA1,Q8TD16,P55011,P51608,P36543,P18583,Q92785,Q12824,Q8IY37,Q6ZXV5,Q03252,Q9UN37,O00139,P07942,P38117,Q71SY5,P36776,Q969G3,P15311,O14974,Q96JM3,Q2VPK5,Q9Y2V7,Q9BSJ2,Q13620,Q6PJT7,Q6P1N0,O14497,P26367,Q13409,Q96N66,Q9UPT5,O95721,Q15042,P20700,Q12904,Q96T60,P51659,O14802,P42345,Q8WXW3,Q16625,Q8TAQ2,P67870,O94992,P23258 51 +Respiratory arrest 0.2921507766841646 0.1454048046019011 0.8843912714564253 1.0 1.0 8 O43772 1 +Polyphagia 0.3110496936801298 0.144140154880517 0.8853897967752493 1.0 1.0 7 Q9H2P0 1 +Muscle hypertrophy of the lower extremities 0.2782323830758851 0.1437006059380232 0.8857368926965241 1.0 1.0 10 P02545,Q14331 2 +Megalocornea 0.2488150676323062 0.1429679244242239 0.8863155135193936 1.0 1.0 15 Q8NFV4,Q15056,Q9UIG0 3 +Celiac disease 0.3907131499338746 0.1420390655318493 0.8870491486622256 1.0 1.0 4 Q6ZRS2 1 +Irregular menstruation 0.360726132724819 0.1417320650750967 0.8872916463370712 1.0 1.0 5 P02545,Q06787 2 +Abnormality of neuronal migration 0.2690312351493246 0.1402173792569806 0.8884882408952044 1.0 1.0 166 P46821,Q96SN8,Q9Y3C6,Q9UBM7,Q96C36,Q96GM5,Q9BVA1,Q8TD16,P55011,P51608,P36543,P18583,Q92785,Q12824,Q8IY37,Q6ZXV5,Q03252,Q9UN37,O00139,O15078,P07942,P38117,Q71SY5,P36776,O60934,Q969G3,P15311,O14974,Q96JM3,P19022,Q2VPK5,Q9Y2V7,Q9BSJ2,Q13620,Q6PJT7,Q6P1N0,O14497,Q13409,Q96N66,O95721,O60826,Q15042,P20700,Q12904,Q96T60,Q15051,O14802,P42345,Q8WXW3,Q16625,Q8TAQ2,P67870,P21333,O94992,Q06787,P23258 56 +Abnormality of reproductive system physiology 0.2623046129503967 0.1392921267410814 0.8892193111824478 1.0 1.0 155 O43837,O60885,P51608,P54098,Q9H7N4,Q13049,Q9NQ48,Q9UN37,O15078,Q9UIG0,P40818,Q9P2D1,O75147,O60934,Q12830,Q8NFV4,Q9NW13,P06748,Q9UQE7,P49257,Q14980,Q99496,Q15056,O95721,P02545,P54132,P35579,Q15042,Q96L73,Q15051,P29401,O43395,O14802,O75298,Q6UN15,Q14683 36 +Abnormality of the gingiva 0.2132277115547221 0.1389097025929916 0.8895215037445705 1.0 1.0 49 P06748,Q9UBM7,O43709,O60832,P49257,Q02241,Q04721,Q8NFV4,Q9NPE3,Q14980,Q15056,Q96JJ3,O75845,Q5JRA6,Q6UN15,Q9UIG0 16 +Vitreous floaters 0.4791838985387326 0.1379668552472026 0.8902666126731615 1.0 1.0 3 P04439,P36405 2 +Lymphoproliferative disorder 0.3588388826788123 0.1377720820134538 0.8904205492422654 1.0 1.0 5 Q05655,P33991 2 +Small intestinal dysmotility 0.479056151239503 0.1377542677077453 0.8904346287604059 1.0 1.0 3 P54098 1 +Microcornea 0.2210351949179977 0.1371277588934494 0.8909298112985828 1.0 1.0 34 Q71SY5,Q9UQE7,Q14683,O60885,O15347,Q15042,O75845,O15078,Q02809 9 +Aplasia hypoplasia affecting the eye 0.2271463932486134 0.1371128861814406 0.8909415669698006 1.0 1.0 108 Q96ST3,Q9UBM7,P18583,O15347,Q96N67,Q9UIG0,O15078,Q9P2D1,Q9Y448,Q8NFV4,Q8WXI9,Q96KP1,P11047,Q15056,O95721,Q15042,Q9H3H1,Q13428,P11166,O14802,Q8N201,Q9NP58,O60828 23 +Telangiectasia 0.2167230322825106 0.1369021425735016 0.8911081452553502 1.0 1.0 44 P06748,Q9UER7,O60832,Q9NPE3,Q14331,Q13043,P02545,Q15437,P54132,P40818 10 +Abnormal blood chloride concentration 0.4770274229001578 0.1344057427157641 0.8930817408093212 1.0 1.0 3 Q9UNF1 1 +Aplasia hypoplasia of the extremities 0.2841545509285347 0.1343430188240484 0.8931313374366119 1.0 1.0 198 Q96ST3,Q9NWH9,P55011,P51608,Q96AY3,P62913,P18583,Q7Z6Z7,Q92785,P48735,Q03252,Q6UX04,Q9P2D1,Q9Y448,Q12830,P50454,P98175,Q15910,Q9UQE7,P61254,Q99496,P62273,O60826,P62081,O75369,P62899,P62857,P02545,O75874,P39019,P46777,Q9H2P0,Q6ZRS2,Q96T60,O14802,P42345,P51610,Q9Y366,Q9BZI7,P21333,Q8NCM8,Q8N3R9,Q14683 43 +Aplasia hypoplasia of the vagina 0.476314055960351 0.1332405989910976 0.8940031037200098 1.0 1.0 3 P51809 1 +Cerebral visual impairment 0.2094003222306416 0.131612381347248 0.8952908918228175 1.0 1.0 71 Q7Z3K3,Q15042,Q71SY5,P55011,P18583,P15311,Q96JM3,P54098,Q9H2P0,Q96N67,Q9BSJ2,P67870,Q9HD42,Q6PJT7,Q6P1N0,Q12904,O60610,Q14683 18 +Renal insufficiency 0.214025366957436 0.1314212893017971 0.8954420482938337 1.0 1.0 94 O60885,Q9NQ48,Q9UIG0,O15078,O43709,Q9Y5K6,Q04721,Q8NFV4,Q8NBM4,Q13043,Q9UQE7,P11047,Q15056,P08397,P35579,Q6ZRS2,Q96L73,Q15051,Q16625,Q8NCM8,Q14683 21 +Stridor 0.2866389717320976 0.1312647168258724 0.8955659021339764 1.0 1.0 8 Q9H0U9,Q14807,P21333 3 +Prominent forehead 0.2045634090567901 0.1311505419460238 0.8956562197236118 1.0 1.0 84 P11166,P42345,P55011,Q12830,P18583,P50454,P19022,Q7Z6Z7,O75369,Q92785,P21333,Q9H2P0,Q8N3R9,Q96L73 14 +Distal amyotrophy 0.2128056373827651 0.1300304410629149 0.8965423426571679 1.0 1.0 63 Q5TAQ9,Q14203,Q71SY5,Q8N2K0,Q8TD16,P43243,Q9Y4W6,Q7Z406,P54098,P50570,P02545,Q14315,P55072,P35573,Q96T60,P25490 16 +Flushing 0.2722476600947685 0.1272191470296883 0.8987669513729168 1.0 1.0 10 P36957,Q01130,Q96L73 3 +Progressive sensorineural hearing impairment 0.2587341982644889 0.1271141901594988 0.898850020446353 1.0 1.0 13 Q7Z406 1 +Aplasia hypoplasia of the nails 0.2045206930452665 0.1264808047318853 0.8993513426199389 1.0 1.0 76 O60832,Q7Z6Z7,Q92785,Q9UIG0,Q6UX04,O43709,Q04721,Q8NFV4,P06748,Q15910,Q9NPE3,Q15056,P02545,O60826,O75369,Q15149,Q96T60,Q96L73,Q5F1R6,O14802 20 +Emg myopathic abnormalities 0.2191998245118183 0.126229827536937 0.8995500012430813 1.0 1.0 33 Q7Z406 1 +Neoplasm of the stomach 0.2352414420022879 0.1257933258287919 0.8998955250233358 1.0 1.0 22 Q99496,Q9NYB0,P20585,P54132 4 +Chronic otitis media 0.2195071008295138 0.1250243942972415 0.9005042380048311 1.0 1.0 31 P78347,P54819,O43709,Q8NFV4,Q15056,Q06787,O15533,Q05655,Q9UIG0,O00192,Q96L73 11 +Abnormal muscle glycogen content 0.3517241379310383 0.123419700896263 0.9017747572788322 1.0 1.0 5 P13807,P08237,P46976,O75648 4 +Retinopathy 0.2180779810857983 0.1230757242134355 0.9020471343822584 1.0 1.0 34 O95169,Q99496,Q8NBM4,Q9BU61,Q5JRA6,P54132,Q13049,Q9NYB0,P11802 9 +Aplasia cutis congenita 0.268407900040339 0.11723915712386 0.9066705379648758 1.0 1.0 10 Q14692 1 +Telecanthus 0.2127381519394865 0.1158272064553209 0.9077894879981914 1.0 1.0 44 P10412,Q9Y366,P02545,P19022,Q96N67,O75369,O60828,P21333,P25490 9 +Abnormal 5th finger morphology 0.230271755940176 0.1153588667869879 0.9081606807903244 1.0 1.0 115 Q9UBM7,O60885,P51608,Q92785,Q13049,Q9NQ48,Q03252,Q9UIG0,O15078,Q15233,Q9P2D1,O75147,O75175,O43709,Q12830,Q8NFV4,Q5JRA6,P11274,Q9UQE7,Q15056,O75369,P54132,Q6ZRS2,Q9Y366,O60828,P21333,Q8NCM8,O75845,Q14683 29 +Depressed nasal bridge 0.2686758666763873 0.1149568033529327 0.9084793609130276 1.0 1.0 171 Q96ST3,Q9NRZ9,Q9UBM7,Q14683,O60885,P55011,P51608,Q9UHD8,P62913,P18583,Q7Z6Z7,Q92785,Q02809,Q9P2D1,Q7Z3K3,O75147,O75175,Q9Y448,O60934,Q969G3,Q12830,Q8WXI9,P19022,Q15910,Q9UQE7,P61254,Q99496,Q9BPU6,P62273,O95721,O60826,P62081,O75369,P62899,P62857,P46777,P39019,Q15042,P61353,Q9H2P0,Q96T60,P42345,P51610,Q9Y366,Q9BZI7,P21333,Q8NCM8,Q8N3R9,P35573 49 +Primitive reflex 0.3174897038475332 0.1146132674105681 0.908751663141143 1.0 1.0 6 P26358,Q14203 2 +Skin vesicle 0.2602687911272763 0.1129870563143106 0.9100408170626176 1.0 1.0 12 P06748,Q9NPE3,O60832,Q15149 4 +Synostosis of metacarpals metatarsals 0.4627495544480401 0.1122999209822219 0.9105856044550518 1.0 1.0 3 O60828 1 +Enterocolitis 0.4564498346196096 0.1105552568993325 0.9119690297239288 1.0 1.0 2 P49748 1 +Abnormality of pain sensation 0.2161462755075562 0.1097717759546816 0.9125903752703308 1.0 1.0 30 Q14683,P17480,P51608,Q96JM3,P25490 5 +Hyperchloremic acidosis 0.4550716648290913 0.1085017641274274 0.9135976812062888 1.0 1.0 2 Q9H4A3 1 +Pseudohypoaldosteronism 0.4550716648290913 0.1085017641274274 0.9135976812062888 1.0 1.0 2 Q9H4A3 1 +Calvarial skull defect 0.2766556523732815 0.1077698491599106 0.9141782604443952 1.0 1.0 8 Q14692 1 +Increased vertebral height 0.3709759087890263 0.1066826733605811 0.9150407288060384 1.0 1.0 4 O75147 1 +Death in adolescence 0.4531422271223706 0.1056720111505273 0.9158425878524196 1.0 1.0 2 P15924 1 +Antiphospholipid antibody positivity 0.4565756823821293 0.1035274841535825 0.9175443374860242 1.0 1.0 3 P49327,Q05655 2 +Myopia 0.2278437164853559 0.1032484507553315 0.91776578721132 1.0 1.0 114 O60885,P36543,P18583,Q15437,Q7Z6Z7,Q92785,Q9HD42,Q9UIG0,Q15233,Q7Z3K3,P30533,O43709,Q12830,Q8NFV4,P98175,Q9UQE7,P11047,Q15056,Q9H3H1,Q96L73,Q5F1R6,O14802,Q9Y366,Q14683 24 +Decreased circulating acth level 0.3112965985873229 0.1022229170171225 0.9185797378875648 1.0 1.0 6 Q99496,Q969G3 2 +Facial diplegia 0.249472898425492 0.1019402689043279 0.918804086472392 1.0 1.0 13 Q9Y281,P54098 2 +Muscle fiber atrophy 0.2283455248180393 0.1015887805808053 0.9190830851730624 1.0 1.0 22 P02545,P54098,P50402,P11047 4 +Recurrent acute respiratory tract infection 0.4546995176579801 0.1009547163325921 0.9195864075808062 1.0 1.0 3 Q15149 1 +X linked recessive inheritance 0.208228629488771 0.1004474137673296 0.9199891293343978 1.0 1.0 58 Q14683,O60832,P51610,P51608,O60828,P38159,Q9BZI7,P98175,O60826,P22314,O15344,P21333,Q15233 13 +Obstructive sleep apnea 0.2584749715025656 0.1000650927984794 0.9202926481098122 1.0 1.0 11 Q15233,Q96KP1 2 +Central nervous system cyst 0.2076222816711988 0.1000121215253549 0.9203347021110369 1.0 1.0 65 Q9P2D1,Q9UBM7,O14802,P36543,O60826,Q92785,Q9BSJ2,Q96KP1,Q8NCM8,O15078 10 +Bundle branch block 0.2545998569576766 0.09866693305955 0.9214027243126756 1.0 1.0 12 P19022,P36543,Q15149 3 +Maturity onset diabetes of the young 0.4481808158765 0.0986357478038291 0.9214274857628144 1.0 1.0 2 P61457 1 +Onion bulb formation 0.2722174710499743 0.0981983395240304 0.9217748009610344 1.0 1.0 8 P02545 1 +Eeg with frontal epileptiform discharges 0.4476295479602967 0.0978751617803578 0.9220314232991652 1.0 1.0 2 Q8NB90 1 +Abnormality of masticatory muscle 0.4476295479602927 0.0978751617803525 0.9220314232991692 1.0 1.0 2 O14908 1 +External genital hypoplasia 0.2474773267354564 0.0965757229969864 0.9230633365977156 1.0 1.0 141 Q96ST3,Q9UBM7,O43837,O60885,O60832,Q7Z6Z7,Q9H7N4,Q13049,Q9NQ48,Q03252,Q9UIG0,O15078,Q9P2D1,Q8NFV4,O14974,P19022,Q8TDP1,Q15910,Q9UQE7,Q9BPU6,Q15056,O60826,P02545,Q01082,Q15042,Q96T60,Q96L73,Q13428,O43395,O60828,Q8NCM8,Q14683 32 +Abnormality of the posterior pituitary 0.2654745008066677 0.095710805552425 0.923750258712257 1.0 1.0 9 Q99496,Q969G3 2 +Malabsorption 0.2071203074151787 0.095142802617808 0.924201400683398 1.0 1.0 57 P06748,Q5F1R6,Q9UIG0,Q9UDY2,P42345,O60832,Q9NPE3,Q01130,Q8NBM4,Q8NFV4,Q15056,P54098,P21333,Q9Y4L1 14 +Neoplasm of the oral cavity 0.2307688439167977 0.0903665001843506 0.927995976726406 1.0 1.0 15 Q99496,Q969G3,P02545,Q8NCM8,Q05655 5 +Neoplasm of the skin 0.2058269981637233 0.0901551128356416 0.9281639537768014 1.0 1.0 47 O60885,O60832,Q99496,Q13043,P02545,Q15437,P20585,P54132,Q01082,P11802 10 +Deviation of the 2nd finger 0.3044484199791375 0.0894549130257728 0.9287203840646204 1.0 1.0 6 Q9Y448 1 +Hypogonadism 0.2138940805273949 0.0890589690469657 0.9290350457269388 1.0 1.0 100 O43837,P51608,P54098,Q9H7N4,O15160,Q13049,Q9NQ48,Q9UIG0,Q9UN37,O15078,Q9P2D1,O43709,Q969G3,Q8NFV4,Q15555,Q9NW13,P51809,Q99496,Q15056,O95721,P02545,Q15042,O43395,O14802 24 +Short palm 0.2198446524951047 0.0888364968954857 0.9292118520171332 1.0 1.0 24 Q96ST3,P11274,Q15555,P02545,P82673,P21333,Q8NCM8 7 +Primary gonadal insufficiency 0.266979569298733 0.0875874162282389 0.9302046041333876 1.0 1.0 8 P49770,Q9UI10,O76024,Q13144,Q9NR50,Q8IY37,P51809 7 +Axial dystonia 0.4430763137679927 0.0859700351192257 0.9314902375232784 1.0 1.0 3 Q9ULV3 1 +Lagopthalmos 0.4429306881423074 0.0857926022699548 0.931631287330255 1.0 1.0 3 O14802 1 +Heteronymous hemianopia 0.3018588728392346 0.084880342896961 0.9323565194770004 1.0 1.0 6 Q99496,Q969G3 2 +Abnormal penis morphology 0.2848094801238857 0.0846831431331688 0.9325132976535612 1.0 1.0 217 Q96ST3,Q9UBM7,O43837,O60885,O60832,P51608,P53597,P62913,Q15437,Q7Z6Z7,Q92785,Q9H7N4,Q13049,O15160,Q9NQ48,O15344,Q03252,Q9UIG0,O15078,Q9P2D1,O75147,Q71SY5,O43709,Q969G3,Q04721,Q8NFV4,Q8WXI9,O14974,Q15555,P19022,Q8TDP1,P06748,Q15910,Q9UQE7,P61254,Q9NPE3,Q9BPU6,Q15056,P62273,O60826,P62081,P02545,P62899,Q7LBC6,Q01082,P62857,P39019,P46777,Q15042,P61353,Q6ZRS2,Q96L73,Q96T60,Q13428,O43395,O14802,P42345,P22314,O60828,P21333,Q8NCM8,O75845,Q14683 63 +Abnormality of the carpal bones 0.2282209742662421 0.0838198460654951 0.9331996686673398 1.0 1.0 17 Q04721,Q9NR45,Q14807,O75369,O75367,P21333 6 +Nephrolithiasis 0.2091310664638128 0.0836631238638159 0.9333242772081976 1.0 1.0 27 O14745,O43709,Q6P1J9,Q8NFV4,Q15056,P50454,Q14697,P07741,Q9UIG0,P40818 10 +Positional foot deformity 0.2279816587370041 0.081036161872103 0.9354131940459828 1.0 1.0 118 Q8TD16,P36543,Q96AY3,Q6ZXV5,P40818,O15078,Q9P2D1,P98175,P10412,Q15910,Q9UQE7,P11047,Q9UGM6,O75369,Q96L73,Q96DF8,P21333,Q8NCM8,Q14683 19 +Axonal regeneration 0.4367245657568187 0.0784641284184765 0.9374588635950948 1.0 1.0 3 P54577,P07196 2 +Fatigue 0.199442696231356 0.0779860186457233 0.9378391746232426 1.0 1.0 86 P06748,Q14203,Q9NWH9,Q9UQN3,Q14980,Q01130,Q02241,Q8NBM4,P43243,Q13043,P54098,P55072,Q01082,Q9UBC1,Q15149,Q6UN15,P40818,P25490 18 +Abnormal head movements 0.2387038965086084 0.0766591261088682 0.9388947214526742 1.0 1.0 13 P35637,P10515,P11166,P41227,Q01082,P20700,Q06787 7 +Myopathic facies 0.2611229989105492 0.0765907493270076 0.9389491183042716 1.0 1.0 8 Q9Y448 1 +Onychogryposis 0.434477788308433 0.0759223537470759 0.939480872466685 1.0 1.0 3 P78536 1 +Abnormal nasal mucosa morphology 0.3494311747313877 0.0749919020920376 0.9402211549453224 1.0 1.0 4 Q13432 1 +Elevated circulating glutaric acid concentration 0.3488692774407189 0.0742593934578355 0.9408039871081896 1.0 1.0 4 P13804,Q92947,P38117 3 +Generalized aminoaciduria 0.3488692774407131 0.074259393457828 0.9408039871081956 1.0 1.0 4 P13804,P16930,P38117 3 +Alopecia of scalp 0.2952538631346544 0.0738351822852893 0.9411415320016688 1.0 1.0 6 P06132,P18074,P19447,Q6P1M0,Q15149 5 +Abnormal muscle fiber protein expression 0.2769096028190664 0.0737542568484778 0.9412059255865366 1.0 1.0 7 P02545 1 +Slender finger 0.2035014156840504 0.0732647192881341 0.9415954661514836 1.0 1.0 44 Q96ST3,P11274,Q12830,P18583,Q9BZI7,Q14807,P82650,O60828,P21333,Q9Y4L1,Q02809 11 +Abnormal sperm motility 0.4318110780053639 0.0729813517997968 0.9418209570406886 1.0 1.0 3 Q14697 1 +Abnormality of the neck 0.2705654390550994 0.0726882533985291 0.9420541962514865 1.0 1.0 186 Q9Y281,Q9UBM7,Q9UQN3,O60885,P51608,P36543,P62913,Q9ULV3,Q7Z6Z7,Q13049,O15160,Q9NQ48,Q9UIG0,O15078,P50402,Q9P2D1,Q7Z3K3,O75147,O75175,Q9Y448,O43709,O60934,Q04721,Q8NFV4,Q12830,Q9NR45,P52815,P19022,P11274,Q9UQE7,P61254,Q15056,P62273,O60826,P62081,O75369,P62899,P62857,Q01082,P39019,P02545,P46777,Q15042,P61353,Q92917,Q6ZRS2,Q13428,P11166,Q8N201,Q9Y2W2,P82650,P82673,P55072,P21333,Q14683 55 +Abnormal metabolism 0.2016189260497573 0.0715890360214742 0.9429289656747886 1.0 1.0 54 Q5F1R6,Q9UDY2,O14678,P51610,P36543,P53597,P62913,Q05682,Q9Y2V7,Q01082 10 +Neonatal onset 0.2184471482049647 0.0715864263203198 0.9429310425863422 1.0 1.0 22 Q9BZI7,Q9UDY2,P53597,P11047 4 +Cystic hygroma 0.2924944812362037 0.0694830635472469 0.944605113400113 1.0 1.0 6 Q06124,Q14739,P61978,Q99567,Q02750 5 +Abnormal 2nd finger morphology 0.2721244520281518 0.0660603630721924 0.947329767572916 1.0 1.0 7 Q9Y448 1 +Facial hemangioma 0.3167925002677947 0.0660514264988386 0.9473368823875524 1.0 1.0 5 O60826 1 +Calvarial hyperostosis 0.2898311278331115 0.0654271141675643 0.947833936341466 1.0 1.0 6 P09651,P55072 2 +Systemic lupus erythematosus 0.2892292194539382 0.0645300347424128 0.9485481926759944 1.0 1.0 6 Q9UJV9 1 +Pulmonary artery stenosis 0.2197088693507382 0.0644805585708063 0.9485875869057468 1.0 1.0 18 O43709,Q8NFV4,Q9UIG0,Q15056 4 +Weakness of muscles of respiration 0.2022944900753523 0.0636308713176125 0.9492641497872044 1.0 1.0 36 Q9Y281,Q8TD16,P43243,P08397,P54098,P02545,P55072,P22314,P50402 9 +Long upper lip 0.418136714443211 0.0631366694404403 0.9496576745431238 1.0 1.0 2 Q96L58 1 +Autoamputation of digits 0.4207333884753189 0.0616276955329725 0.9508593210109012 1.0 1.0 3 P39210,Q9H4A3 2 +Acral ulceration 0.4207333884753189 0.0616276955329725 0.9508593210109012 1.0 1.0 3 P39210,Q9H4A3 2 +Short digit 0.2557134810136919 0.0603378685534039 0.9518865421298373 1.0 1.0 162 Q96ST3,Q9UBM7,O60885,P55011,P51608,P62913,Q15437,Q7Z6Z7,Q92785,Q9NQ48,Q03252,Q6UX04,Q9P2D1,Q7Z3K3,O75147,O75175,Q9Y448,Q04721,Q12830,Q5JRA6,Q9UQE7,P61254,Q9BPU6,P62273,O60826,P62081,O75369,P62899,P62857,P02545,P39019,P46777,Q9H2P0,Q6ZRS2,Q96T60,P11166,P42345,P51610,Q9Y366,Q9BZI7,P21333,Q8NCM8,Q8N3R9,Q14683 44 +Secondary growth hormone deficiency 0.3121875071812184 0.060064994625738 0.9521038698451596 1.0 1.0 5 Q99496,Q969G3 2 +Hemiplegia hemiparesis 0.1990506136087008 0.0583856476823223 0.9534414467600718 1.0 1.0 46 Q15051,P11166,P42345,Q99496,Q8NBM4,O15078 6 +Abnormality of the gastric mucosa 0.2169144218686554 0.0579643036447927 0.9537770622627127 1.0 1.0 17 O43709,Q8NFV4,Q15056,Q14739,Q15477,Q05655,Q9UIG0 7 +Abnormality of the midface 0.2545619238891801 0.0568844483639984 0.9546372426598162 1.0 1.0 161 Q8NC56,Q14683,Q8TD16,P51608,P36543,P18583,O75179,O15078,Q15233,Q9P2D1,Q7Z3K3,O75147,O75175,O60934,Q04721,Q12830,P50454,Q9BSJ2,P25490,P10412,P11274,Q14807,O60826,O75369,P62857,P54132,Q01082,P02545,Q15042,Q13428,O14802,P42345,P51610,P17980,Q8N201,Q9Y366,Q9Y2W2,Q96JJ3,Q9BZI7,O60828,P21333,O75845,P35573 43 +Hernia 0.2488267587474487 0.0561906365010547 0.95518994036864 1.0 1.0 152 Q96ST3,P46821,Q9NRZ9,Q9UBM7,O60885,P51608,P24928,P36543,Q92785,Q32P28,Q6ZXV5,Q9UIG0,Q6UX04,Q02809,Q9P2D1,Q7Z3K3,Q9Y448,Q71SY5,O43709,Q969G3,Q04721,Q8NFV4,O14974,P50454,Q15910,P11274,Q9UQE7,Q99496,Q15056,O60826,O75369,P62857,Q7LBC6,Q9H2P0,Q6ZRS2,Q96L73,Q5F1R6,Q96T60,P42345,O14678,Q96JJ3,Q96DF8,P22314,P21333,Q8NCM8,Q14683 46 +Elongated superior cerebellar peduncle 0.4101433296582037 0.0556280266013186 0.9556381370692132 1.0 1.0 2 P36405 1 +U shaped upper lip vermilion 0.4130135097876983 0.0545133823801861 0.9565261468464092 1.0 1.0 3 P28482,P46100 2 +Regional abnormality of skin 0.2425410105436223 0.0544752136633123 0.956556555890986 1.0 1.0 143 Q96ST3,Q9UBM7,O60885,O60832,P55011,Q96AY3,Q15437,Q7Z6Z7,Q9UIG0,P18206,Q9P2D1,O75175,O43709,Q12830,Q8NFV4,P98175,Q9Y2V7,P25490,P06748,Q15910,Q9UQE7,Q9NPE3,Q9BPU6,Q15056,O95721,P02545,P54132,Q01082,Q15042,Q15149,Q9H2P0,Q92917,P42345,P78536,P21333,Q8N3R9,Q14683 37 +Abnormality of the synovia 0.203215765594529 0.0540668268168792 0.95688192193793 1.0 1.0 94 Q9Y281,Q5F1R6,Q9UQE7,O14802,Q8TD16,P55011,P36543,Q96AY3,Q9Y366,O75369,P21333,Q8NCM8,Q03252,Q14683 14 +Abnormality of retinal pigmentation 0.1965007951650632 0.0526602571076105 0.9580026052970236 1.0 1.0 87 Q15051,O43395,Q8N183,Q13049,O15078 5 +Right bundle branch block 0.2408498727023142 0.051158996117528 0.9591988253914518 1.0 1.0 9 P36543,Q15149 2 +Abnormal circulating carbohydrate concentration 0.1978418563115516 0.0508827538635441 0.9594189481296982 1.0 1.0 43 Q8N183,O75380 2 +Nephritis 0.2082650536259077 0.0497189051046094 0.9603463909951546 1.0 1.0 23 P35579,Q9Y5K6 2 +Abnormal waist to hip ratio 0.2605076567867893 0.0494866579638848 0.9605314695755092 1.0 1.0 7 Q9Y6M1 1 +Abnormal serum interleukin level 0.3251516822945444 0.0474762917798681 0.9621336254426068 1.0 1.0 4 P49327,Q05655,Q15833 3 +Subcapsular cataract 0.2422793934599692 0.0471865170133215 0.9623645734172316 1.0 1.0 8 Q9H444,P20839,O43837,Q8N2K0,P26367 5 +Milia 0.4040449498158169 0.047034199894456 0.9624859701067814 1.0 1.0 3 Q15149 1 +Limb fasciculations 0.403883104304151 0.0469067499351476 0.9625875483474408 1.0 1.0 3 P55072 1 +Abnormal sternum morphology 0.223932437124899 0.0452626131557184 0.9638979872593608 1.0 1.0 120 Q9Y281,Q9NWH9,O60885,P55011,P51608,P24928,Q96AY3,Q15437,Q7Z6Z7,Q9UIG0,Q9Y4L1,O75147,P17480,O43709,Q8NFV4,P98175,Q9UQE7,Q15056,P02545,O75369,Q96L73,Q8N201,Q9Y366,Q9Y2W2,Q9BZI7,O60828,P21333,Q8NCM8,Q14683 29 +Spinal cord lesion 0.2366936617875443 0.0452527904745288 0.9639058166026568 1.0 1.0 9 O75298,Q04721 2 +Median cleft palate 0.3974641675854319 0.0452379499237647 0.9639176455350252 1.0 1.0 2 Q14739 1 +Motor neuron atrophy 0.207667706022764 0.0450368873163716 0.9640779069445458 1.0 1.0 22 P09651,Q14203,P38935,Q9UQN3,Q92804,P43243,P22314,Q92734,Q99986,P55072,P22626,Q9NW13 12 +Antineutrophil antibody positivity 0.3224877209535776 0.0449519262896878 0.9641456274513104 1.0 1.0 4 P61011 1 +Abnormality of endocrine pancreas physiology 0.2745584988962439 0.0448370751688564 0.9642371730850074 1.0 1.0 6 P16930,P40763,Q14739,O00330,P25490 5 +Chylothorax 0.3992280121312341 0.0433519063511265 0.9654210148005612 1.0 1.0 3 Q02750,P52732 2 +Abnormality of the palpebral fissures 0.2854717596045089 0.0420943287426161 0.9664235011732616 1.0 1.0 243 Q96ST3,Q9UBM7,P55011,P51608,P36543,P18583,O95319,P38159,O75179,Q7Z6Z7,Q92785,Q13049,Q92974,O15078,Q15233,Q6UX04,Q9P2D1,O60934,Q12830,Q8NFV4,Q8WXI9,O14974,Q96JM3,P98175,P19022,Q9BSJ2,Q96KP1,P25490,Q13409,Q15910,Q99496,Q9BPU6,Q15056,O95721,O60826,P02545,Q9HCK8,P62857,P39019,Q9H2P0,Q9GZZ9,Q92917,Q96L73,Q5F1R6,Q13428,O14802,P42345,P51610,Q8N201,Q9BZI7,Q96DF8,O60828,P21333,Q8N3R9,Q14683 55 +Cellulitis 0.2960060617600659 0.0417479439253443 0.9666996335280786 1.0 1.0 5 P02545 1 +Retrocollis 0.396746622553069 0.0415432593639237 0.966862806617691 1.0 1.0 3 P35637,O75569 2 +Hydroxyprolinuria 0.3916758544652575 0.0410780208726006 0.9672336966139244 1.0 1.0 2 P30038 1 +Aplasia hypoplasia of the cerebellum 0.2453550548125875 0.0394338019736909 0.9685445307814304 1.0 1.0 151 Q9Y3C6,Q9UBM7,Q8TD16,O60885,O60832,P00374,P36543,P18583,Q92785,Q9UN37,O15078,Q15233,P07942,Q9P2D1,P98175,Q96KP1,Q9UQE7,Q9BPU6,Q9UGM6,O60826,Q15042,Q92917,Q96L73,Q15051,O14802,Q16625,Q8N201,P21333,Q8NCM8,Q14683 30 +Small nail 0.1950625739645175 0.0393143758840758 0.968639745179482 1.0 1.0 56 Q5F1R6,Q15910,O14802,Q9NPE3,Q8NFV4,Q15056,O60826,Q7Z6Z7,Q92785,Q15149,Q9UIG0,Q96L73,Q6UX04 13 +Lower limb muscle weakness 0.1940452910253769 0.0391323267490888 0.9687848876816564 1.0 1.0 45 Q14203,O75298,Q99496,Q7Z406,P02545,Q14315,Q15149,Q96T60 8 +Abnormality of the antitragus 0.3149476006618965 0.0383035944287146 0.9694456249514072 1.0 1.0 4 Q92643,Q8IY17,O94766 3 +Abnormal nerve conduction velocity 0.1934528918821158 0.0366456279489409 0.9707675621017856 1.0 1.0 44 Q5TAQ9,P43243,P02545,Q7Z406,P54098,Q9GZY8,Q96T60 7 +Increased hepatic glycogen content 0.3113623827909628 0.0353920202878739 0.9717671476151172 1.0 1.0 4 P06737,P36871,P31040 3 +Abnormal circulating dicarboxylic acid concentration 0.1927888033284394 0.0350539013560095 0.972036760189039 1.0 1.0 45 P14314,P11166,O14678,P51610,Q02241,P53597,Q01082,P48735 8 +Paralysis 0.1911009266498293 0.0346114752175199 0.9723895510829784 1.0 1.0 51 Q9UQN3,P31040,P54098,P50402,Q15233,P36776,O14908,Q92804,P50336,P09651,Q14203,P08397,P02545,O94979,P20700,P11166,P38935,P43243,Q9NP58,P55072,P36957 21 +Anisocytosis 0.247111611639671 0.033872002552637 0.9729792190987508 1.0 1.0 7 Q02241 1 +Absent toenail 0.2307525950489035 0.0333922924899559 0.9733617559387766 1.0 1.0 8 O14497,P11274,Q14739 3 +Abnormal foot bone ossification 0.3817781773960643 0.0318421310863303 0.9745979479093408 1.0 1.0 3 P21333 1 +Incomplete penetrance 0.1923548898182813 0.0308995183874537 0.9753496740121576 1.0 1.0 33 Q9NWH9 1 +Convex nasal ridge 0.2012224761153006 0.0307883239829578 0.9754383521188266 1.0 1.0 21 O14802 1 +Talipes valgus 0.2612649088162803 0.0304151165249639 0.9757359891897855 1.0 1.0 6 Q15233 1 +Abnormal electrophysiology of sinoatrial node origin 0.218304687036565 0.029667575870394 0.97633217124013 1.0 1.0 11 P02545,P0DP25,P36957 3 +Anorectal anomaly 0.1895775559994404 0.0290517560929388 0.9768233125999513 1.0 1.0 84 Q96ST3,P06748,Q9P2D1,Q13428,O60934,Q9NPE3,O60832,Q8NFV4,Q15056,O60826,Q15437,P20585,P78536,O60828,Q8NCM8,Q9UIG0 16 +Thick eyebrow 0.1893259839665602 0.0271992721463984 0.978300796235586 1.0 1.0 48 O75147,Q9UQE7,O60885,Q12830,P98175,Q96N67,Q92785,Q9BSJ2,Q01082,Q14683 10 +Perimembranous ventricular septal defect 0.2401324868893167 0.0271098633470815 0.9783721078397514 1.0 1.0 7 P46100,O60216,Q9UHX1,Q5SRE5,P0DP25,O94979 6 +Vertical nystagmus 0.3654906284454135 0.0263044702784936 0.979014489379716 1.0 1.0 2 P49959 1 +Elevated lactate pyruvate ratio 0.2977753513363293 0.0257299056078171 0.9794727705231858 1.0 1.0 4 P53597 1 +Ectopia lentis 0.2124848836072226 0.0253124236959585 0.9798057644305596 1.0 1.0 12 Q9Y467 1 +Renal cortical microcysts 0.3630099228224843 0.0252126606689014 0.9798853384136024 1.0 1.0 2 Q8TD19 1 +Uncombable hair 0.3630099228224802 0.0252126606688997 0.9798853384136036 1.0 1.0 2 Q15477 1 +Metaphyseal cupping 0.3655913978494571 0.023490780289357 0.9812587927204685 1.0 1.0 3 O95831,Q14739 2 +Slanting of the palpebral fissure 0.272933770705015 0.0223620834398125 0.982159125814557 1.0 1.0 211 Q96ST3,Q9UBM7,P55011,P51608,P36543,P18583,O95319,O75179,Q7Z6Z7,Q92785,Q13049,Q92974,O15078,Q15233,Q6UX04,Q9P2D1,O60934,Q12830,Q8WXI9,O14974,Q96JM3,P19022,Q9BSJ2,Q96KP1,P25490,Q13409,Q15910,Q9BPU6,O95721,O60826,P02545,Q9HCK8,P62857,P39019,Q9H2P0,Q9GZZ9,Q96L73,Q5F1R6,Q13428,O14802,P42345,P51610,Q9BZI7,O60828,P21333,Q8N3R9,Q14683 47 +Abnormality of hair pigmentation 0.1946738407061002 0.0220108472698529 0.9824393027647916 1.0 1.0 23 P06748,Q9NPE3,P02545,Q9UBM7 4 +Spontaneous hematomas 0.3609043286462584 0.0214458555274948 0.9828899945438648 1.0 1.0 3 Q6YHK3,P17301 2 +Immunologic hypersensitivity 0.1880936091364208 0.0212575587855108 0.9830401993641756 1.0 1.0 34 P42345,Q01130,Q8NBM4,Q13043,Q01082,Q6ZRS2 6 +Abnormality of the voice 0.2410493897566493 0.0197554750701884 0.9842384366908288 1.0 1.0 150 Q96ST3,O60885,P55011,P51608,Q7Z406,P54098,Q7Z6Z7,Q9UIG0,Q15233,Q9P2D1,O75175,O43709,Q12830,Q8NFV4,P50454,Q8TDP1,Q13409,Q14203,Q15910,Q9UQE7,Q9BPU6,P11047,Q15056,P08397,P02545,P54132,Q01082,Q15149,Q6ZRS2,Q96L73,P43243,Q9BZI7,Q96DF8,O60828,P21333,Q8N3R9,Q14683 37 +Testicular atrophy 0.2475165562913873 0.0186018698526084 0.9851587111682544 1.0 1.0 6 P52788,O76024,P54098,Q9NX24,P04637 5 +Cerebellar hypoplasia 0.2303130510462239 0.018032397072348 0.9856130084825688 1.0 1.0 135 Q9Y3C6,Q9UBM7,Q8TD16,O60832,P00374,P36543,P18583,Q92785,Q9UN37,O15078,Q15233,P07942,Q9P2D1,P98175,Q96KP1,Q9BPU6,Q9UGM6,O60826,Q15042,Q96L73,O14802,Q16625,Q8N201,P21333,Q8NCM8 25 +Absent fingernail 0.2077129056891237 0.0174987273041878 0.9860387481558424 1.0 1.0 10 Q96T60 1 +Contractures of the joints of the lower limbs 0.1885641909583828 0.0174486458525299 0.986078701272996 1.0 1.0 55 Q8TD16,Q96AY3 2 +Abnormal natural killer cell physiology 0.3471188309897935 0.0162957793118664 0.9869984247166615 1.0 1.0 3 Q05655,Q15833 2 +Decreased pulmonary function 0.2633515966559425 0.0162954496809622 0.9869986876891528 1.0 1.0 5 Q99496,Q969G3 2 +Decreased fertility in females 0.2261551916626941 0.0161062276755474 0.9871496451936176 1.0 1.0 7 P54132,P51809 2 +Hip dislocation 0.1901190968272314 0.0154660445510948 0.9876603737747038 1.0 1.0 68 Q9Y281,Q5F1R6,O75147,Q9UBM7,Q9UQE7,Q8TD16,O60885,P55011,P36543,Q9BPU6,P02545,O75369,P21333,Q14683 14 +Abnormality of blood volume homeostasis 0.3438103115522418 0.0152367961774109 0.9878432659602404 1.0 1.0 3 O00330,P31153 2 +Glaucoma 0.2028604540585462 0.0130245768952758 0.9896081849956628 1.0 1.0 102 Q9UBM7,O43837,O60885,P62913,Q9UIG0,Q8NFV4,Q8TDP1,Q9UQE7,P61254,Q15056,P62273,O60826,P62081,P62899,P62857,P46777,P39019,O43395,P21333,Q14683 20 +Hyperparathyroidism 0.25664100595726 0.0126917677863301 0.9898737062935898 1.0 1.0 5 Q6P1J9,P25490 2 +Primary hyperparathyroidism 0.271601322439973 0.0124876411522307 0.9900365628761544 1.0 1.0 4 P25490 1 +Abnormal serum iron concentration 0.2695601497701905 0.0117104981223101 0.9906565879020488 1.0 1.0 4 Q02241 1 +Periventricular leukomalacia 0.1865909470133893 0.0115204017921817 0.99080825259715 1.0 1.0 14 P18074,P36776,P18583,Q68CP9,Q5JTZ9 5 +Limb dysmetria 0.3285258966899103 0.0111245630903622 0.991124065939774 1.0 1.0 3 P54098 1 +Glycosuria 0.2169892643642786 0.0105279515896063 0.9916000651417268 1.0 1.0 7 P02545 1 +Supernumerary tooth 0.2152911951421467 0.0096219403373392 0.9923229208196064 1.0 1.0 7 Q9UBM7,P21281,Q9UHX1,Q6DKJ4,P62266,O60488 6 +Spastic tetraplegia 0.1834123752866963 0.0093294953116398 0.992556247714308 1.0 1.0 44 Q9Y3C6,Q01082,P51608,Q9UGM6,Q8TDP1,P82650,Q13813,Q96KP1 8 +Abnormal sharpey fiber morphology 0.2329142080046652 0.009087362572233 0.99274943349749 1.0 1.0 6 P02545,Q6P1J9 2 +Long philtrum 0.230614014722341 0.0090011860937827 0.9928181895669856 1.0 1.0 138 Q96ST3,Q9UBM7,O60885,P55011,P51608,P36543,Q7Z6Z7,Q92974,Q9UIG0,O75147,O75175,O43709,Q12830,Q8NFV4,O14974,P19022,Q96KP1,Q15910,Q9UQE7,Q9BPU6,Q15056,Q9H2P0,Q96L73,P11166,P42345,Q16625,P51610,Q8N201,Q9BZI7,Q8NCM8,Q8N3R9,Q14683 32 +Shyness 0.261374457814317 0.008911901228497 0.9928894257251588 1.0 1.0 4 Q15233 1 +Prominent antitragus 0.3148607664736641 0.0083879024431947 0.9933075006204062 1.0 1.0 3 Q92643,O94766 2 +Anonychia 0.1814851107911257 0.0078957632693739 0.9937001578502715 1.0 1.0 14 Q96T60,Q15149,P11274,Q14739 4 +Abnormal morphology of myocardial trabeculae 0.2573313705674663 0.0077051897684213 0.993852208878122 1.0 1.0 4 Q15233 1 +Spontaneous abortion 0.3104494072235958 0.0076649290235575 0.99388433135626 1.0 1.0 3 Q9NQX3,P50570 2 +Alacrima 0.2300691003602337 0.007556189247529 0.993971090632044 1.0 1.0 6 P55011,Q96IJ6 2 +Fulminant hepatic failure 0.3038323683484922 0.0067089481541035 0.9946470740044976 1.0 1.0 3 Q16836,Q96RP9 2 +Abnormal morphology of the great vessels 0.2622865425121113 0.005886793842464 0.995303045208797 1.0 1.0 193 P46821,Q9UBM7,P55011,P53597,P62913,P18583,Q7Z6Z7,Q92785,O15160,Q6ZXV5,Q9UIG0,Q6UX04,Q15233,Q02809,Q9P2D1,O75175,Q71SY5,O43709,Q969G3,Q04721,Q8NFV4,Q12830,P98175,Q8TDP1,P19022,Q9Y2V7,P11274,Q9UQE7,P61254,Q99496,Q9BPU6,Q15056,P62273,O60826,P62081,O75369,P62899,Q7LBC6,Q01082,P62857,P39019,P02545,P46777,P61353,Q6ZRS2,Q96L73,P29401,Q13428,O14678,Q96DF8,O60828,P21333,Q8N3R9,Q14683 54 +Elevated urinary carboxylic acid 0.2068767394421653 0.0056655231105189 0.9954795907640552 1.0 1.0 7 P08397 1 +Decreased number of large peripheral myelinated nerve fibers 0.2232339955849853 0.0042637050016989 0.9965980659147252 1.0 1.0 6 O15269,Q7LG56,P54098,P19367,P07196 5 +Increased intramyocellular lipid droplets 0.2209031812686438 0.0032585111196027 0.9974000888873956 1.0 1.0 6 Q9Y4W6,P53597 2 +Abnormality of iron homeostasis 0.2322758620689696 0.0032457566871808 0.9974102653982916 1.0 1.0 5 Q6PGP7,P28288,Q15477,Q02241 4 +Abnormality of the nasal alae 0.2542965436197194 0.0032044430138438 0.997443228768964 1.0 1.0 178 Q96ST3,Q9UBM7,O43837,O60885,Q14683,P51608,P36543,P10586,O75179,Q96N67,Q92785,Q7Z6Z7,O15344,O15078,Q6UX04,Q7Z3K3,O75147,O75175,Q9Y448,Q71SY5,Q969G3,Q04721,Q12830,Q8WXI9,P98175,Q9Y2V7,Q13409,P11274,Q9UQE7,Q99496,O75369,Q7LBC6,Q01082,Q15042,Q15149,Q9H2P0,Q6ZRS2,Q96T60,P11166,O43395,O14802,Q16625,P51610,Q9Y366,Q9BZI7,Q96DF8,O94992,O75845,P35573 49 +Proximal amyotrophy 0.1731194690265538 0.0031122377727915 0.9975167975402692 1.0 1.0 14 Q16637,P35637,Q13642,Q9BTV4,O14979,Q9H9S5,P02545,Q92734,Q8WXH0,Q14204,Q06210,P50402,P07196 13 +Highly arched eyebrow 0.1865844858980491 0.0028741995952877 0.9977067236757228 1.0 1.0 69 Q9P2D1,O75175,P11274,Q9UQE7,O60885,P55011,Q99496,Q12830,Q9BPU6,Q7Z6Z7,Q8N3R9,O15078,Q14683 13 +Pituitary growth hormone cell adenoma 0.2332757642368751 0.0025173385257855 0.997991456577316 1.0 1.0 4 Q14697 1 +Distal sensory impairment 0.1803298534491586 0.0021173111702756 0.9983106313690636 1.0 1.0 46 Q5TAQ9,O14802,P43243,P02545,P54098,P18887,Q96T60 7 +Ocular anterior segment dysgenesis 0.1969420620706061 0.0019567003978076 0.9984387799587068 1.0 1.0 98 P62913,Q9UIG0,Q9UN37,O15078,Q8NFV4,P19022,Q8TDP1,P61254,P11047,Q15056,P62273,P02545,P62081,P62899,P62857,P46777,P39019,Q15042,P17980,P21333 20 +Chondrocalcinosis 0.2265165694953873 0.0017095690541224 0.9986359619105184 1.0 1.0 5 P02545 1 +Anarthria 0.2155077262693124 0.0011443800707639 0.9990869170091434 1.0 1.0 6 P35637,P54886,Q99720,Q8WVX9,P22314 5 +Gastroesophageal reflux 0.2274435067986012 0.0010936509268753 0.9991273929844886 1.0 1.0 136 Q9UBM7,O60885,P55011,P51608,P24928,P53597,O95319,P18583,P54098,Q9HD42,Q6ZXV5,Q9UIG0,Q15233,Q9P2D1,Q7Z3K3,Q9Y448,Q8NFV4,Q96JM3,P35658,Q9UQE7,Q15056,O60826,P54132,Q9H2P0,Q9GZZ9,Q6ZRS2,Q96L73,P14314,O14678,P21333,Q14683 31 +Ridged nail 0.2234482758620731 0.0009812220365091 0.999217098211979 1.0 1.0 5 P18074,O60832,P19447,P26639 4 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e0bb9e5b0e121386acd8578eeb71410e84a36a3c --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 4th finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil count", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rapid eye movement sleep", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of cytokine secretion", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of tumor necrosis factor secretion", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal fissure", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar impression", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central opacification of the cornea", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cephalohematoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic myelogenous leukemia", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clinodactyly of the 3rd finger", "Clinodactyly of the 4th finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased csf homovanillic acid", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to anti cd3", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatochalasis", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the 4th finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Digital flexor tenosynovitis", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Exudative retinal detachment", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal autonomic seizure", "Focal aware seizure", "Focal cognitive seizure with deja vu jamais vu", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonadotropin deficiency", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Hemothorax", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent macular lesion", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypoautofluorescent retinal lesion", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic iris stroma", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired renal concentrating ability", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating interleukin 6", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interphalangeal joint erosions", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intervertebral space narrowing", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal perforation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intraventricular hemorrhage", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limbal dermoid", "Limbal stem cell deficiency", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid dysgenesis", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Percussion myotonia", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Perineal fistula", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent bleeding after trauma", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychic epileptic aura", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Punctate opacification of the cornea", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal nonattachment", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short term memory impairment", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Thinning of descemet membrane", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic dysplasia", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thrombophlebitis", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABHD11", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKT1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG12", "AMPD2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANXA11", "AP1B1", "AP1S1", "AP1S2", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP4M1", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP6", "ARV1", "ARVCF", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG5", "ATG7", "ATIC", "ATL3", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATPAF2", "ATRX", "ATXN10", "AURKA", "B3GALT6", "B3GAT3", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BBS4", "BCAP31", "BCAT2", "BCKDK", "BCR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BRIP1", "BUB1B", "BUB3", "BUD23", "C12orf57", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CAPN1", "CAPN5", "CARS", "CASK", "CAST", "CC2D1A", "CCDC22", "CCDC47", "CCT5", "CD109", "CD2AP", "CD320", "CDC42", "CDC45", "CDC73", "CDH2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKN2A", "CELF2", "CENPE", "CEP250", "CEP290", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN6", "CLCN7", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT3", "CNP", "COA3", "COA7", "COASY", "COG5", "COG6", "COG7", "COG8", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COX1", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2A1", "CSNK2B", "CSTB", "CTBP1", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CTU2", "CUL3", "CUL4B", "CWC27", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCAF8", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIP2B", "DKC1", "DLAT", "DLD", "DLG3", "DLST", "DNAAF5", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DPP9", "DPYSL5", "DSC3", "DSE", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S3", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "FAH", "FAM50A", "FANCG", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GAL", "GALK1", "GALM", "GALNS", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GBA", "GCDH", "GCLC", "GDAP2", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLT8D1", "GM2A", "GMPPA", "GMPPB", "GNA11", "GNAI2", "GNAI3", "GNAO1", "GNPAT", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GPKOW", "GPRASP2", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPD1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IGF2R", "IGHMBP2", "IKBKB", "IMPAD1", "IMPDH1", "INF2", "INTS1", "IQCB1", "IRF2BPL", "IRS4", "ITCH", "ITGA2", "ITPA", "IVD", "JAGN1", "JAM3", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIAA0319L", "KIDINS220", "KIF11", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KLC2", "KNSTRN", "L2HGDH", "LAMB1", "LAMC1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2L", "LMBRD1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LRRC8A", "LRSAM1", "LSS", "LZTFL1", "MACF1", "MAD1L1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP3K7", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCFD2", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MECR", "MED17", "MED23", "MED25", "MESD", "MFF", "MFN2", "MFSD8", "MIA3", "MICU1", "MID1", "MIF", "MIPEP", "MMAB", "MOCOS", "MOCS1", "MOGS", "MPDU1", "MPG", "MPI", "MPP5", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVD", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NADK2", "NADSYN1", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND1", "ND5", "NDE1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA6", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEFL", "NEK9", "NELFA", "NEMF", "NFKBIL1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPM1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSBPL2", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PANX1", "PARK7", "PARN", "PAX6", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDK3", "PDP1", "PDSS1", "PDSS2", "PDXK", "PEPD", "PEX14", "PEX19", "PEX5", "PEX6", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POMGNT2", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRSL1", "RAB11B", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD50", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "REEP2", "REPS1", "RFC1", "RFC2", "RFT1", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF2", "RNF213", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS28", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RREB1", "RRM2B", "RRP7A", "RTN2", "RTN4IP1", "SALL2", "SAMHD1", "SAR1B", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCYL1", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC27A4", "SLC2A1", "SLC33A1", "SLC39A14", "SLC9A3R1", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMG8", "SMN1*", "SMPD4", "SMS", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPAST", "SPATA5", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQOR", "SRCAP", "SRP54", "SRP72", "SRSF2", "SSBP1", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD7", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TAF15", "TALDO1", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCOF1", "TCTN3", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIMM22", "TIMM50", "TIMMDC1", "TJP2", "TKFC", "TKT", "TMCO1", "TMEM126A", "TMEM126B", "TMEM165", "TMEM199", "TMEM38B", "TMEM43", "TMEM70", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TPRKB", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIM32", "TRIP12", "TRIP13", "TRIP4", "TRIT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSPYL1", "TTC19", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWNK", "TXNDC15", "UBA1", "UBA5", "UBAC2", "UBE4A", "UBE4B", "UBIAD1", "UBR7", "UBTF", "UFC1", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC119", "UNC45A", "UNG", "UPF3B", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP8", "USP9X", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VIPAS39", "VMA21", "VPS13A", "VPS13D", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP11", "WDR1", "WDR34", "WDR36", "WDR4", "WDR45B", "WDR73", "WFS1", "WNK1", "WRN", "XPNPEP3", "XRCC1", "YARS", "YARS2", "YIPF5", "YME1L1", "YWHAE", "YWHAG", "YY1", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZNF644", "ZNF687", "ZPR1"], "leading_proteins": ["AARS2", "ABCB6", "ABCD3", "ABCD4", "ABHD11", "ABHD12", "ACADVL", "ACAT1", "ACSF3", "ACSL4", "ACTN1", "ACTN4", "ADAM17", "ADAR", "ADNP", "AFG3L2", "AGL", "AIFM1", "AIMP1", "AK2", "ALDH18A1", "ALDH4A1", "ANKRD17", "ANLN", "APRT", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARL3", "ARVCF", "ASPSCR1", "ATP6V1B2", "ATP6V1E1", "ATRX", "B3GALT6", "B3GAT3", "BAZ1B", "BCR", "BICD2", "BLM", "BMS1", "BPTF", "BRCA1", "BRD4", "BUB1B", "BUD23", "CALD1", "CALM3", "CC2D1A", "CCDC22", "CD109", "CD2AP", "CDC42", "CDC73", "CDH2", "CDK4", "CDK5RAP2", "CDK6", "CDKN2A", "CELF2", "CEP290", "CFL2", "CHAMP1", "CHD4", "CHD7", "CHD8", "CHMP1A", "CHMP2B", "CHMP4B", "CIZ1", "CLASP1", "CLPB", "CNOT3", "COASY", "COG6", "COPB2", "CSNK2B", "CTNNA1", "CTU2", "CUL4B", "CWC27", "DAXX", "DCAF8", "DCTN1", "DDX3X", "DDX41", "DHCR7", "DHFR", "DHX30", "DHX37", "DIAPH1", "DKC1", "DLAT", "DLD", "DLST", "DNAJB11", "DNAJB6", "DNAJC21", "DNAJC3", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPM1", "DPYSL5", "DSG2", "DSP", "DYNC1H1", "DYNC1I2", "DYNC2H1", "EFL1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF4H", "ELMO2", "EMD", "EPHX2", "ERCC2", "ERCC3", "ESS2", "ETFA", "ETFB", "EWSR1", "EXOC2", "EXOC7", "EZH2", "EZR", "FAH", "FAR1", "FARSA", "FASN", "FDXR", "FH", "FHL1", "FIP1L1", "FKBP10", "FKRP", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FRG1", "FUS", "GANAB", "GATAD2B", "GATB", "GCDH", "GFM1", "GFPT1", "GIPC1", "GLDC", "GMPPA", "GPHN", "GPKOW", "GTF2I", "GYG1", "GYS1", "H2AFY", "HADH", "HADHB", "HAX1", "HCFC1", "HELLS", "HERC2", "HEXIM1", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HMBS", "HMGB3", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPK", "HNRNPU", "HPS6", "HSD17B4", "HSPA9", "HSPD1", "HUWE1", "HYOU1", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT52", "IGF2BP2", "IGHMBP2", "IMPDH1", "INTS1", "IQCB1", "IRF2BPL", "IRS4", "ITGA2", "KDM3B", "KIDINS220", "KIF11", "KIF20A", "KIF22", "KIF23", "KIF2A", "KNSTRN", "LAMB1", "LAMC1", "LARS2", "LBR", "LEMD2", "LEMD3", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRPAP1", "LZTFL1", "MAD1L1", "MAGED2", "MAGT1", "MAP1B", "MAP2K1", "MAP3K7", "MAPK1", "MAPRE2", "MAT2A", "MATR3", "MBOAT7", "MCM4", "MECP2", "MED17", "MED25", "MESD", "MFF", "MIA3", "MID1", "MOGS", "MPP5", "MPV17", "MRE11", "MRPL12", "MRPS22", "MRPS35", "MRPS7", "MSH3", "MSN", "MTHFD1", "MTOR", "MYH14", "MYH9", "MYO6", "NAA10", "NANS", "NBN", "NCAPD3", "NDUFAF2", "NDUFAF3", "NDUFB11", "NDUFB8", "NDUFS3", "NDUFS6", "NDUFS7", "NEFL", "NEK9", "NFKBIL1", "NHP2", "NONO", "NOP10", "NOTCH2", "NOVA2", "NPM1", "NSD1", "NUBPL", "NUMA1", "NUP188", "NUP214", "NUP88", "NXN", "OBSL1", "OCLN", "OCRL", "P3H1", "PALLD", "PAX6", "PBRM1", "PCBD1", "PDCD6", "PDHX", "PDP1", "PFKM", "PGM1", "PGM3", "PHGDH", "PIBF1", "PIGK", "PIGS", "PIK3C2A", "PLAA", "PLEC", "PLOD1", "PLPBP", "PMPCA", "PMS1", "PNKP", "PNPLA6", "POGZ", "POLG", "POLR1C", "POLR2A", "POLR3A", "PPIL1", "PPOX", "PPP1R12A", "PQBP1", "PRCC", "PRKAR1A", "PRKCD", "PRKCSH", "PRKRA", "PRPF3", "PRPF31", "PRPF8", "PSMC3", "PTPN11", "PTPRF", "PUF60", "PYCR2", "PYGL", "QARS", "QDPR", "RAB3GAP1", "RAD21", "RAD50", "RANBP2", "RBM10", "RBM28", "RBM8A", "RBMX", "REEP2", "REPS1", "RFC1", "RIPK1", "RNASEH2A", "RNASEH2C", "RNF2", "RPL11", "RPL13", "RPL21", "RPL26", "RPL27", "RPL31", "RPL5", "RPS10", "RPS14", "RPS19", "RPS23", "RPS24", "RPS28", "RPS29", "RPS7", "RRM2B", "RTN2", "SALL2", "SAMHD1", "SAR1B", "SBDS", "SC5D", "SCAF1", "SCYL1", "SDHA", "SEC23A", "SEC23B", "SEC31A", "SEPT9", "SERPINH1", "SF3B4", "SH3GL1", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC25A20", "SLC27A4", "SLC2A1", "SLC9A3R1", "SLTM", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMS", "SNAP29", "SNRPE", "SON", "SPART", "SPATA5", "SPTAN1", "SPTBN1", "SPTLC1", "SRCAP", "SRP54", "SRSF2", "STAT1", "STAT3", "STK4", "STUB1", "STXBP2", "SUCLG1", "SYNE2", "TAF15", "TAPBP", "TARS", "TCOF1", "TERF2IP", "TFG", "TIMM22", "TJP2", "TKT", "TMEM126B", "TMEM43", "TMPO", "TMTC3", "TOR1AIP1", "TP53", "TPP2", "TRAPPC11", "TRIM28", "TRIM32", "TRIP4", "TRIT1", "TRMU", "TSPYL1", "TTC37", "TUBB", "TUBB2B", "TUBG1", "TUBGCP2", "UBA1", "UBA5", "UBAC2", "UBTF", "UNC119", "UPF3B", "UQCRFS1", "UROD", "USP8", "VAMP7", "VARS1", "VCL", "VCP", "VPS16", 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0.0013457312682723 0.0009242109214801 2.0791314186223096e-06 +Focal adhesion 11 41 2.720025132324209 0.0065276954786663 11.701456310679612 34.34708737864078 -0.7945880401802174 0.4725920807326323 4.779679663427712 4.901299239495934 1.0663587430269696 0.3597031250604345 1.0 0.026201726433941 0.1375179432078189 0.0421567666761504 0.0547726598219007 +Viral myocarditis 3 12 2.0451190065591693 0.0408431268920139 4.031553398058253 11.228155339805824 0.0319814940949768 0.5543700591424958 2.250452924114055 1.5125313108034515 0.956572263574295 0.3192370987906132 1.0 0.1706778675257841 0.3128615540599918 0.0655524699240303 0.1120371510488811 +Systemic lupus erythematosus 10 13 2.009181313593749 0.0445179086856619 5.356796116504855 12.009708737864075 -1.0355846009408072 0.3299670753803522 2.457676190917427 0.8389214716257521 0.9979723129163846 0.2980238386293583 1.0 1.0 1.0 1.0 0.450369534817547 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..70579cc70313f286b643a4c8c5cc95304f7049e2 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 18.033333333333335 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7b14d2c3c5ac7f2cae70d2bcfaf86f23d9f71cbb --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..364c3fd1fd4f1eed5a9d62d6bb71a9f3e587d735 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,52 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ribosome 0.4911604260117937 4.099168048445645 4.1463790150686464e-05 0.0074358531908049 0.0037317411135618 74 P62913,P83731,P61247,P26373,P50914,P62917,P84098,P62841,Q02878,P62861,Q9UHA3,P47914,P46776,P46778,P62753,P61254,P62424,P62750,P62273,P62081,P62899,P46777,P62857,P39019,P46779,P61353,P46782,P36578,P83881,P05387,P40429 31 +Spliceosome 0.433395043445133 3.2549126126804406 0.0011342726138079 0.1847699615590485 0.0487506684301628 105 Q9Y3C6,Q13573,Q9Y3B4,P38159,Q01081,P09012,Q13243,Q9P013,Q13435,O75400,P52272,Q8WYA6,P62314,Q86V81,P08579,P41223,O43290,Q86XP3,P62304,Q00839,P0DMV9,Q08170,O14776,Q9ULR0,P08621,Q9UKV3,Q96I25,Q96NC0,Q99459,Q7L014,O43395,Q01130,P49756,P54652,O75494,Q9Y2W2,P55769,Q9BUQ8,P51991,O60828,P11142,P84103,Q15459 43 +Focal adhesion 0.4711970848455022 2.7200251323242095 0.0065276954786663 0.6923636668216768 0.1068168351054499 41 Q9Y490,Q13464,Q9NWH9,P11047,O14974,Q14315,O75369,O96013,P21333,P07942,P18206 11 +Viral myocarditis 0.6054682900038961 2.0451190065591693 0.0408431268920139 0.9994502872928144 0.2827601092524044 12 P35579,Q7Z406,P30511 3 +Systemic lupus erythematosus 0.5809313383735066 2.009181313593749 0.0445179086856619 0.9997245395449984 0.2953925017091999 13 P05455,P16104,P84243,P62314,Q9P0M6,O75367,O43707,P19474,P12814,P62805 10 +Tight junction 0.3989320952140364 1.913099638412049 0.0557352980481957 0.9999671242270476 0.3066062835671109 40 Q07157,O43491,Q9UDY2,Q9Y2J2,Q16625,P55196,Q7Z406,Q13813,P67870,P35580,P35579,Q8N3R9,Q14247 13 +Regulation of actin cytoskeleton 0.3683995450768941 1.9022186950415816 0.0571425697446374 0.9999748646450004 0.3066062835671109 54 Q9Y281,Q13177,Q13464,P59998,Q92888,O96013,Q86VI3,P15311,O14974,O75116,Q7Z406,Q9Y6W5,P46940,P35580,Q9UQB8,P35579,O60610,P18206 18 +One carbon pool by folate 0.5884261066005879 1.7937827176501722 0.0728478564647794 0.9999987776904375 0.3411722705632871 10 P00374 1 +Adherens junction 0.453862264254893 1.7871041392368154 0.0739206586220455 0.9999990076261256 0.3411722705632871 23 Q07157,Q9NWH9,P55196,P10586,Q9Y6W5,P46940,P67870,Q9UQB8,P18206 9 +Endocytosis 0.3415931577761864 1.6907157118969178 0.0908911120166109 0.9999999644481122 0.3718272764315902 64 Q9UQN3,Q9Y3E7,Q9NWH9,P30511,Q9UN37,P40818,Q8N6T3,Q9NP79,P09496,Q9NZZ3,P0DMV9,Q9H444,Q9H4M9,Q15075,O14964,P54652,Q6WKZ4,P61020,P11142 19 +Cell adhesion molecules cams 0.5094275070692026 1.6591322251275225 0.0970891509544764 0.9999999896228798 0.3718307908894843 14 Q9BY67,Q16625,P10586,P19022,P30511 5 +Base excision repair 0.4550760661256267 1.5549882501267476 0.1199488677268969 0.9999999998973348 0.4073735130347443 19 P09874,Q9NRF9,P18887,P39748 4 +Ecm receptor interaction 0.5360349966844042 1.2971788320977335 0.194569662294179 1.0 0.5346024550422679 8 P07942 1 +Vascular smooth muscle contraction 0.4322129591952277 1.2950778670303191 0.1952933692094018 1.0 0.5346024550422679 17 Q05682,O14974 2 +Pathogenic escherichia coli infection 0.3941471806973665 1.2170456883747358 0.2235868330759658 1.0 0.5758387340547788 22 P59998,Q13464,P19338,Q16625,P15311,Q92974,Q14247 7 +Homologous recombination 0.4698122175765777 1.1947660436528975 0.232178450683234 1.0 0.5882552518718664 12 O60934,Q92878,P54132 3 +Antigen processing and presentation 0.4078717728231484 1.1868111982210077 0.2353021007487465 1.0 0.5882552518718664 19 P34932,P0DMV9,P54652,P30101,P30511,O15533,P08238,P11142,P07900 9 +Bladder cancer 0.5788911313031764 1.1497532457375177 0.2502455169986712 1.0 0.593744464882206 6 P27361,P42771,P28482,P11802 4 +Axon guidance 0.349543066413927 1.1494742159356734 0.2503604927647145 1.0 0.593744464882206 27 Q9Y281,Q9NWH9 2 +Thyroid cancer 0.4927247066668672 1.1351031504566895 0.2563321017084856 1.0 0.593744464882206 9 P12270,Q16204,P28482,Q92734,P27361 5 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.4182803491473981 1.0360636520811528 0.3001724480803118 1.0 0.638373188747244 14 P17301,P19022,P02545,P35221,Q14126,P50402,P12814,O43707 8 +Dorso ventral axis formation 0.600841010854595 1.0182755146224196 0.3085470412278346 1.0 0.638373188747244 5 P27361,P62993,Q04721 3 +Type i diabetes mellitus 0.5423645579164451 0.9737997732890186 0.3301559656995567 1.0 0.6753190207490933 6 P10809,P30511 2 +Fc gamma r mediated phagocytosis 0.3224753229438329 0.7702237153015269 0.4411671985456429 1.0 0.8066871402407964 25 Q9Y281,P59998,P49006,Q9UQ16,Q9Y6W5,P50570,P29966,Q05655 8 +Non homologous end joining 0.4944953361679127 0.7488241360700315 0.4539632102482218 1.0 0.809043344996831 6 Q92878 1 +Folate biosynthesis 0.5769547488423399 0.7266286169586291 0.4674534928022029 1.0 0.813869265922136 4 P00374 1 +Glyoxylate and dicarboxylate metabolism 0.4066640670557458 0.7190903134585442 0.4720852752424496 1.0 0.813869265922136 10 P11586,P13995,Q6UB35,Q9UBQ7,Q99798 5 +Renal cell carcinoma 0.3401327151908173 0.7046933265143434 0.4810011052631704 1.0 0.813869265922136 20 P11166,Q9NWH9 2 +Small cell lung cancer 0.3520626326244069 0.6790634976646555 0.4970976296665887 1.0 0.813869265922136 15 P07942 1 +Pathways in cancer 0.2703031749447332 0.6731108222025911 0.5008767894214938 1.0 0.813869265922136 58 P12270,P20585,Q9NWH9,P07942 4 +Citrate cycle tca cycle 0.3098539091272514 0.6642516403240774 0.5065292670447672 1.0 0.813869265922136 25 P48735 1 +Vasopressin regulated water reabsorption 0.3394853549811908 0.64707371109129 0.5175842386013441 1.0 0.813869265922136 18 Q13409,Q12846,Q14203,O43237,Q9Y6G9,P61020,Q8NCM8 7 +Prion diseases 0.4716188829930969 0.6454045636967003 0.5186650467231888 1.0 0.813869265922136 6 P11047 1 +Leukocyte transendothelial migration 0.3083755742710453 0.6074302874326858 0.5435653936018998 1.0 0.8434635417960514 24 Q13464,Q16625,P55196,P15311,P35221,O75116,P26038,P12814,P18206 9 +Cytosolic dna sensing pathway 0.394101105648737 0.5896735769809351 0.5554095131870129 1.0 0.8542922517436179 9 Q7Z434,Q9NZI8,O14802 3 +Dna replication 0.278534808924081 0.5259781158665182 0.5989034121861296 1.0 0.8624209135480267 32 Q04837,P25205,Q8TDP1,P33991,P35251,Q9NRF9,P39748 7 +Glioma 0.3275917854360495 0.4615633204109888 0.6443945033002496 1.0 0.9133150440475978 14 P42771,P62993,P42345,P28482,P27361,P0DP25,P11802 7 +Glutathione metabolism 0.2705310093081189 0.3661504030271642 0.7142528487902009 1.0 0.962987567921746 25 P48735 1 +Basal transcription factors 0.3341777863290409 0.311242392027322 0.7556163581292259 1.0 0.9810718179337404 9 Q00403,P78347,P29083,P13984,P35269,P32780 6 +Non small cell lung cancer 0.2991705636067981 0.2411456104964653 0.8094422635537688 1.0 0.993751571942325 12 P42771,P28482,Q13043,P27361,P62993,P11802 6 +Notch signaling pathway 0.3098326113742335 0.2199555309929657 0.8259057876699509 1.0 0.993751571942325 9 Q13573 1 +Amyotrophic lateral sclerosis als 0.2908399933121474 0.1943267986623622 0.8459200032809431 1.0 0.993751571942325 11 Q9UER7 1 +Mapk signaling pathway 0.2269716838057345 0.1873244887617039 0.851406223567486 1.0 0.993751571942325 40 Q9UER7,P0DMV9,P16949,P54652,Q13043,Q14315,O75369,P21333,P11142 9 +Pyrimidine metabolism 0.1962171133471276 0.0572114615339057 0.9543767481322982 1.0 0.9946745906645658 50 Q05682,O14802 2 +Rna polymerase 0.2265860368739247 0.0531636712303405 0.9576015008194916 1.0 0.9946745906645658 13 P24928,O14802 2 +Dilated cardiomyopathy 0.2346051386247882 0.0490244712189242 0.9608997941710308 1.0 0.9946745906645658 10 P02545,P50402,P17301,P67936 4 +Erbb signaling pathway 0.2075664677853546 0.0414754099278823 0.9669168960163894 1.0 0.9946745906645658 16 Q13177,P46108,P42345,O96013,P62993 5 +Cell cycle 0.1946559818859447 0.0412493383666724 0.9670971207899576 1.0 0.9946745906645658 54 Q13416,Q9Y6D9,Q9UQE7,Q12834,O00311,P33991,Q14683 7 +Hypertrophic cardiomyopathy hcm 0.218045883182877 0.0293645732465287 0.9765738270666252 1.0 0.9946745906645658 11 P17301,P67936,P02545,P06756,P50402 5 +Primary bile acid biosynthesis 0.3244211686879732 0.0135276311733754 0.9892068411291306 1.0 0.9961232384927006 2 P51659 1 +Pentose phosphate pathway 0.1869469026548724 0.0117949364697501 0.9905892205010745 1.0 0.9961232384927006 14 P11413,P29401,Q01813,P08237,P60891,P36871,Q96G03,P52209,P06744,P04075,P09972,P37837,O95336 13 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8d01354fbb5be3ca066fdc0232ace0c616bf5d0e --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADO", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEX1", "APP", "APRT", "AQR", "ARF6", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKA", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BAIAP2", "BCAS2", "BCAT2", "BCR", "BECN1", "BIRC6", "BLM", "BLVRA", "BNIP1", "BPNT1", "BRCA1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CASK", "CBR1", "CCDC12", "CCDC6", "CD47", "CDC20", "CDC23", "CDC27", "CDC42", "CDC45", "CDC5L", "CDC7", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2A", "CDS2", "CETN2", "CFL1", "CFL2", "CHD8", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHORDC1", "CHPF2", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "COASY", "COMT", "COX1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CROT", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CXADR", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBT", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS4", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSE", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERO1A", "ETNK1", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAH", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGA1", "GGCT", "GGH", "GGPS1", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPAT", "GNPDA1", "GNS", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACL1", "HADH", "HADHA", "HADHB", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HMBS", "HMGB1", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGF2BP1", "IGF2R", "IKBKB", "ILK", "IMPDH1", "IMPDH2", "INPP4A", "IQGAP1", "IQGAP2", "IQGAP3", "IRS4", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITPK1", "IVD", "JAM3", "JUP", "KARS", "KDELR1", "KDSR", "KEAP1", "KIDINS220", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LAPTM4A", "LARS", "LARS2", "LCMT2", "LDHA", "LDHB", "LDLR", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LYPLA1", "M6PR", "MAD1L1", "MAD2L1", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MFSD8", "MGAT1", "MGST1", "MGST2", "MGST3", "MID1", "MIF", "MMAB", "MOGS", "MPG", "MPHOSPH6", "MPI", "MPP5", "MPST", "MPV17", "MRE11", "MRPL13", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MTR", "MUT", "MVD", "MYH10", "MYH14", "MYH9", "MYL6", "NAA16", "NADSYN1", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCBP1", "NCK1", "NCKAP1", "NCL", "NCSTN", "ND1", "ND5", "NDUFA10", "NDUFA11", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NIT2", "NLN", "NME1", "NME2", "NNT", "NOTCH2", "NPC1", "NPC2", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NT5C2", "NT5C3A", "NTHL1", "NUDT12", "NUDT5", "NUDT9", "OAT", "OCLN", "OCRL", "OGDH", "ORC2", "ORC3", "ORC5", "OXA1L", "OXCT1", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAX6", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDSS1", "PDSS2", "PECR", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHF5A", "PHGDH", "PHKA1", "PI4KA", "PI4KB", "PIAS2", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PLA2G15", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLXNB2", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "PPA1", "PPA2", "PPAT", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTDSS1", "PTDSS2", "PTGES2", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PXMP2", "PXMP4", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "RAB11B", "RAB11FIP1", "RAB13", "RAB23", "RAB31", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RABEP1", "RAC1", "RAD21", "RAD23B", "RAD50", "RALA", "RAPGEF2", "RARS", "RARS2", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RCOR1", "RDH11", "RDX", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFT1", "RHEB", "RIPK1", "RNASEH2A", "RNASEH2C", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRM2B", "RSL24D1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SC5D", "SCARB2", "SCD", "SCLY", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEPHS1", "SETD1A", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC33A1", "SLC38A2", "SLIT2", "SLK", "SLTM", "SMAP1", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNAP29", "SNAP47", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORD", "SORT1", "SPCS2", "SPCS3", "SPHK2", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SV2A", "SYMPK", "TAB1", "TAF10", "TALDO1", "TAP1", "TAPBP", "TARS", "TARS2", "TARSL2", "TBL1XR1", "TBPL1", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM7SF2", "TOLLIP", "TOMM40", "TP53", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TRA2A", "TRA2B", "TRIM21", "TRIM25", "TRIM32", "TRIP12", "TRMT11", "TROVE2", "TSG101", "TSTA3", "TTC37", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBR5", "UCK2", "UGCG", "UGDH", "UGP2", "UGT8", "UMPS", "UNC45A", "UNG", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USP39", "USP8", "UXS1", "VAMP7", "VANGL1", "VAPA", "VARS1", "VARS2", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS25", "VPS28", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VTA1", "WARS", "WARS2", "WASF2", "WBP11", "WDR61", "XAB2", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZFYVE16", "ZMAT2", "ZYX"], "leading_proteins": ["ACIN1", "ACO2", "ACTN1", "ACTN4", "AFDN", "ALDOA", "ALDOC", "ALYREF", "ARFGAP1", "ARHGEF1", "ARHGEF2", "ARPC4", "BAIAP2", "BLM", "BUD31", "CADM1", "CALD1", "CALM3", "CCDC6", "CDC20", "CDC5L", "CDC7", "CDH2", "CDK4", "CDKN2A", "CFL2", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CLTA", "CRK", "CSNK2B", "CTNNA1", "CTNNBL1", "CTTN", "CWC15", "DAXX", "DCTN1", "DDX23", "DDX42", "DDX46", "DHFR", "DIAPH1", "DNM2", "DNM3", "DSG2", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "EEA1", "EHD1", "EMD", "EPB41L2", "EPB41L3", "EZR", "FAU", "FEN1", "FLNA", "FLNB", "FLNC", "G6PD", "GPI", "GRB2", "GRHPR", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HGS", "HLA-F", "HNRNPA3", "HNRNPM", "HNRNPU", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPD1", "IDH2", "IGF2BP1", "IQGAP1", 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0.6597076662585866 0.940627334720274 0.312981393641603 1.0 1.0 0.1027954944442906 0.0020770710993276 4.87808128990818e-06 +Apoptosis induced dna fragmentation 4 9 2.542568295305835 0.0110041093866335 4.461165048543689 9.480582524271844 -1.2396777487494677 0.2413940671270342 1.815774087232708 0.7956871918457745 1.1955398659006715 0.28131040332984 1.0 1.0 1.0 0.0284635326710383 9.75534858956266e-05 +Rho gtpases activate rocks 4 10 2.528386877339607 0.0114588006443514 3.941747572815534 9.66747572815534 -0.468060111442931 0.4811160724413961 2.196976044954919 1.475893817349503 0.9571429756724884 0.3092624866833871 1.0 0.0038211367015083 0.0146091852998709 0.0010229806952196 0.0017743753624758 +Sensory processing of sound 7 19 2.5161209135835527 0.0118654468094292 6.407766990291262 17.59223300970874 -0.1979151622355178 0.6784882163123832 4.008938782183972 1.606642118569903 0.6752876378754417 0.2791249623345367 1.0 1.0 1.0 0.0741296824894279 0.0121842961258669 +Eukaryotic translation initiation 31 103 2.503282100200894 0.0123047423363726 45.19417475728155 100.27669902912622 -0.7708270245582552 0.3856475380014496 15.071066765335097 1.8144888222625024 2.0151499677382354 0.3857325415106563 1.0 0.1106003446312499 0.0001376275081644 0.0005480019626126 1.243221814239935e-09 +Endosomal sorting complex required for transport escrt 6 16 2.471080575666483 0.0134705463460473 4.351941747572815 10.570388349514564 -0.0957602001200055 0.5322106115127874 2.7903998245901382 2.52028601487162 0.98051093227169 0.3223117902032849 1.0 1.0 1.0 0.1669228189673315 0.0139902560164694 +Dna double strand break repair 16 56 2.4419889236667687 0.0146065947643667 16.038834951456312 53.13834951456311 -0.617182781530225 0.4998065885301411 7.896382765455599 7.66582285174556 1.0587528741215466 0.3506553565985733 1.0 0.4923830768256354 0.3899534463534457 0.2459274936765676 0.0161311976150157 +Semaphorin interactions 9 20 2.43286647873207 0.0149798237048877 7.711165048543689 20.174757281553397 -0.5523693332434992 0.5007556321630265 3.8694185110344 2.736581328642038 0.9780833670769368 0.326926104117902 1.0 0.0230307909850112 0.0803264485176453 0.0061725204362492 0.0281454476703931 +Meiotic synapsis 7 16 2.41002925486686 0.0159512414053022 6.155339805825243 15.49757281553398 -0.5443126206257733 0.4889366647353366 2.925473263690994 1.8308292810495423 0.9431609251180718 0.3148843297999692 1.0 1.0 1.0 1.0 0.0160305095638712 +Met promotes cell motility 2 10 2.399324966168192 0.016425330482191 2.5776699029126213 7.694174757281553 -0.416298593998174 0.5236744672961856 1.6149442888485217 1.4171847686483998 0.8053538137952436 0.2891238669477767 1.0 0.0087935329278829 0.0325598174288622 0.0332834196813974 0.1659016353191164 +Rna polymerase ii transcription termination 20 47 2.361118724720271 0.0182198965409596 17.20873786407767 44.70145631067961 -0.86103981823213 0.4512938122200936 7.0779379202652954 3.184564992246008 1.0646102763598504 0.3419500531624954 1.0 0.2778293030066073 0.0039428820669095 0.0001962948008104 0.0012458006436326 +Transport of mature transcript to cytoplasm 21 66 2.3391546046830047 0.0193274335131836 22.179611650485437 63.12378640776699 -0.6291260216114811 0.5624135506222746 9.223322687761865 3.3978458671491603 1.0645020276827344 0.342276085943197 1.0 0.3295231102555642 0.0081420868521756 4.115001538411393e-06 0.000516116301773 +Epha mediated growth cone collapse 3 7 2.305557856881328 0.0211353503938118 3.2524271844660193 7.905339805825243 -0.0134632275998438 0.547687937966358 2.2239580154325385 1.9739248348060368 0.9359809307366288 0.3136862668708668 1.0 0.1070183553885475 0.2030300441679912 0.0179536348510701 0.0236194052560011 +Hsf1 dependent transactivation 7 14 2.297973637281691 0.0215632896113888 5.618932038834951 14.279126213592232 -0.3527812083435748 0.559467497755984 3.734895902585274 1.5176154051836428 0.8414177838280088 0.310660480416511 1.0 0.1373006943976843 0.2562935091164666 0.5256573230515567 0.0139902560164694 +Processing of capped intron containing pre mrna 68 195 2.282650441018733 0.0224509672153796 61.44660194174757 182.83009708737865 -0.6525536485470969 0.5600064525169441 22.544983363510543 8.980305689776722 1.3401481761909957 0.3579178268520561 1.0 0.328104280891315 0.0005473765456786 1.5138171526400192e-10 3.095813447125801e-10 +Rho gtpases activate cit 3 9 2.282279375727279 0.0224728513882901 3.815533980582525 9.70388349514563 -0.350178243819446 0.5301743086314644 2.2758656640254453 1.3985722490959065 0.8784917953955078 0.3016836993355851 1.0 0.0034296220851759 0.0131546828557762 0.0090496486299172 0.0098879726868235 +Sumoylation of transcription cofactors 5 13 2.2643792414244577 0.0235507996047057 5.114077669902913 11.735436893203884 -0.8398302807631189 0.4162141800138964 2.6756898890411236 2.747533148363699 0.840353098064034 0.300914418096352 1.0 1.0 1.0 0.6393520558322405 0.1376237189726102 +Influenza infection 40 128 2.2641136152964263 0.0235671277855586 49.45388349514563 124.4878640776699 -0.8167232636376969 0.467267315983218 15.884605402777892 3.5145119813370975 1.4357011449695982 0.3598614446069196 1.0 0.0369955408328181 0.0001080130010811 7.85543034867417e-05 2.969804519279221e-09 +Hats acetylate histones 9 26 2.2623235560661654 0.0236774200732099 8.810679611650485 22.805825242718445 -0.8070191836874221 0.4559083773817732 3.976640837901002 3.944538444770874 0.8427399396454849 0.3244399185888312 1.0 1.0 0.5897423730476636 0.179290741124566 0.0716509178019204 +Hcmv late events 13 42 2.2560021691086707 0.0240704952875674 10.37135922330097 35.987864077669904 -0.2604077894188442 0.6891915910802267 5.492311934470012 2.6961584143216353 0.7074004247624673 0.3052328571555278 1.0 0.2633971592089756 0.4582375595260778 0.0039921427401633 0.0304236608893936 +Met activates ptk2 signaling 2 5 2.255658669573114 0.0240920158525033 1.546116504854369 3.203883495145631 -0.375626064025358 0.5027097455470905 1.0498772309269555 1.1135461007364955 1.0289026340653995 0.3207307769097394 1.0 0.0038211367015083 0.0146091852998709 0.0105546488673461 0.0624183143373935 +Dna double strand break response 8 21 2.2480100237383303 0.0245755507570895 7.893203883495145 19.75242718446602 -0.7928100036570543 0.4599626060551284 3.496635335171425 2.8175712415143255 0.8084337731376008 0.3122666274431318 1.0 0.2145132052110039 0.0832266786685991 0.1182182962859381 0.03080273588529 +Late endosomal microautophagy 3 12 2.2465461320427917 0.0246690481303706 3.1140776699029127 9.53640776699029 -0.192904720125058 0.5410937568609512 1.918002569874466 1.6491052910322457 0.8720209875939886 0.2872740435593883 1.0 1.0 0.2489059409173845 0.0332834196813974 0.0504521665366165 +Constitutive signaling by aberrant pi3k in cancer 2 6 2.2282843576492044 0.0258615587711403 2.174757281553398 5.774271844660194 -0.2312510600523671 0.5665601521045002 1.5084048313574552 1.2148027942893045 0.8124325514238734 0.2930913762043971 1.0 0.1457663642848915 0.27085351108605 0.1845674517893196 0.2031992995383869 +Cell cell communication 9 29 2.21340217456658 0.0268699308814257 8.745145631067961 27.050970873786408 -0.4904844478317756 0.5288276393586533 4.248426405216309 2.9129479994835736 0.8288134482328866 0.3138499136930213 1.0 1.0 1.0 0.1286320927932822 0.0897105158156102 +Budding and maturation of hiv virion 5 13 2.211408756824696 0.0270075439949453 3.5606796116504853 9.8252427184466 -0.079275741488951 0.5338846887196986 2.2873029702979513 2.149405808458996 0.9682623114536008 0.3142584444053341 1.0 1.0 1.0 0.1410845222447507 0.0402069493791732 +G alpha 12 13 signalling events 5 9 2.2053256626540367 0.0274312502894165 3.094660194174758 8.20388349514563 -0.2865224513498776 0.5105953396039956 1.9947189088462312 2.6571362908176197 0.9375276623284956 0.3035753444817528 1.0 1.0 1.0 0.758038297770574 0.7736965906956426 +Ercc6 csb and ehmt2 g9a positively regulate rrna expression 10 14 2.18769594054114 0.0286917579686187 6.007281553398058 12.45631067961165 -0.8896070493117743 0.3866497917243187 2.9233650958842756 1.421244491098621 0.8959073330962924 0.3113893370014395 1.0 1.0 1.0 0.0276080433055301 0.0089325963600969 +Rho gtpases activate ktn1 2 7 2.1812254415651435 0.029166745938848 2.9150485436893203 7.54126213592233 0.0260570012898481 0.6160636396117691 2.014526552481555 1.0953327105581845 0.7799505097179867 0.2872828207774705 1.0 1.0 1.0 0.2390677645130265 0.0141665154869097 +Runx1 interacts with co factors whose precise effect on runx1 targets is not known 11 16 2.171569722506624 0.029888132841632 6.662621359223301 14.031553398058252 -0.7146030043719374 0.4648983984365347 3.3768574065260446 2.400743112010757 0.8716735527823855 0.3192860398449827 1.0 1.0 1.0 1.0 0.8350628750672632 +Mitochondrial translation 24 65 2.162854586173523 0.0305523656393891 18.78640776699029 54.44417475728155 -0.5144488569198282 0.5469432198403718 9.671196837047138 5.612424674482629 1.1580697551554602 0.3552289835032928 1.0 0.0760657989123155 0.2316260817282189 0.0077526419092464 0.0148600283171556 +Attenuation phase 6 11 2.154294025328184 0.0312171211307314 5.5 11.118932038834952 -0.4337073514143714 0.4842081320796569 3.2144244075486763 0.9179603949209442 0.9436906363931746 0.3126089504565827 1.0 0.1026081339138497 0.1951188871774342 0.4211551865871433 0.020271757680103 +Calnexin calreticulin cycle 5 10 2.153944574009929 0.0312445188000816 3.3470873786407767 7.963592233009709 -0.0363494619413967 0.5320983101397908 2.04640728565277 1.2251945392339945 0.9768841139763874 0.3167179925679953 1.0 0.1070183553885475 0.2030300441679912 0.1082353444632946 0.09905667817091 +Metabolism of folate and pterines 1 8 2.1439755362657187 0.032034847008616 1.8106796116504855 8.368932038834952 1.1027495377425318 0.3107646321591615 1.2630224668311476 0.7725922983430199 0.836443902773376 0.2729501818402672 1.0 0.0711332726649859 0.1375212864755611 0.0509703724436577 0.1641299211995837 +Rho gtpases activate pkns 5 20 2.1182036671180704 0.0341578227605863 6.701456310679611 19.070388349514563 -0.6522259842150975 0.4949181272620779 3.8592591742852456 1.6944789973574843 0.9170476614712676 0.336513671367134 1.0 0.0163255968864409 0.0583817580096799 0.0741296824894279 0.0121842961258669 +Sema4d induced cell migration and growth cone collapse 3 6 2.106517370466404 0.0351594358562397 2.849514563106796 6.131067961165049 0.0137836048830172 0.4937642018007891 1.7042706942567776 1.0461700029120171 1.0124337106022097 0.3060261841703338 1.0 0.0847528009868792 0.1626892876910785 0.0090496486299172 0.0098879726868235 +Epigenetic regulation of gene expression 26 49 2.097805179656514 0.0359223587836436 19.41747572815534 42.99514563106796 -1.2342556202270925 0.3568884878092889 7.137381793821183 4.250639669526318 1.1738716287747466 0.3574577146020241 1.0 1.0 1.0 0.1054307555033435 0.229113977717335 +Sensory processing of sound by outer hair cells of the cochlea 5 14 2.0960804683692733 0.0360750533168277 5.344660194174757 12.723300970873789 -0.1102522522144516 0.6398584593428776 3.3052834478966804 1.4914451116507836 0.78467998862094 0.2966859344433833 1.0 1.0 1.0 0.1243944683174773 0.0063685282240186 +Alk mutants bind tkis 3 7 2.0791024790669708 0.0376079323002382 2.5388349514563107 6.196601941747573 -0.3775703885431983 0.5828747145823898 1.7069096022445671 0.799082062444466 0.7061738515121062 0.2866124731781508 1.0 1.0 1.0 1.0 0.113339965404402 +Negative regulation of the pi3k akt network 2 16 1.998478782006851 0.0456647780273662 4.133495145631068 13.235436893203884 0.0967515447406026 0.614339852942537 2.7251337221087875 2.411623663140556 0.75893813969026 0.2882669708035213 1.0 0.2633971592089756 0.4582375595260778 0.4515682837178238 0.5881219771746483 +Hdacs deacetylate histones 6 16 1.995814754472004 0.0459540902012785 6.614077669902913 13.390776699029129 -0.9216890307937898 0.3846533048332129 3.12430122265599 1.938424036750778 0.846316866971374 0.3089780404632911 1.0 1.0 1.0 0.0741296824894279 0.3092787829323835 +Cell junction organization 6 19 1.971532584263568 0.0486629897461843 6.516990291262136 17.089805825242717 -0.7472786842770813 0.4279885179297663 3.237703049808721 2.0323101210975607 0.9810436921549112 0.329905090545082 1.0 1.0 1.0 0.146040514257028 0.1216432455234702 +Rhobtb gtpase cycle 16 30 1.961546627771368 0.0498152913131413 8.859223300970873 28.87378640776699 0.0244963620421633 0.6760155465171244 3.879819255453924 1.4692948685301523 0.7472097297483927 0.3008902581889185 1.0 0.1499686155438198 0.2780273254227372 0.1934880896161839 0.2160393117631846 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..25edc624e5017573da4ca2fde2da2931a8a28cb7 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 1409, + "title": "Average number of proteins per term", + "value": 20.875088715400995 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8b07514bb9797cfe8c75ccd9f234be3fca3fbd04 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..646b0f0a56be39bdaa19cb49ffe664f6c192a0d5 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,485 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Metabolism of rna 0.331015904399188 6.019449895271256 1.750108183842134e-09 2.4658993942654556e-06 2.4659024324425666e-06 496 Q9Y3C6,Q9UKX7,O00233,P38159,P83731,P49790,Q2NL82,Q9HC36,Q9NZI8,Q05048,P62917,P84098,P52272,P62841,Q8IZD4,P55735,Q86V81,P47914,P08579,O43290,Q08170,Q9ULR0,Q8IY81,P62424,Q9UKZ1,Q9NPE3,P62750,Q9BY77,Q99848,P78316,P62081,P62899,P55036,Q13769,Q9ULX3,Q92733,Q7L014,O43395,Q9UQ35,P82979,Q15007,Q01130,P17980,O75494,Q9Y2W2,Q96GA3,P40429,Q96EE3,O75152,Q9BVC5,O60832,Q13573,P13984,P24928,Q15637,Q9H2H8,Q9NR30,Q6UX04,P26599,Q9P013,Q8IX12,P12270,O75175,O75400,O43709,Q9H814,Q7Z3B4,P35658,P46778,Q8WUA2,P08621,P61254,P16383,P19338,Q99459,Q969X6,O43818,P46779,P61353,Q9C0J8,Q92917,Q8NFH5,P46782,P11940,P62263,P83881,O00566,Q15287,Q9Y3Y2,Q14692,Q05519,O75937,O94992,P11142,Q6UN15,Q15459,P62913,P46087,P09012,P26373,P61247,P50914,Q13435,Q13243,Q8WYA6,Q9H6R4,P62314,P62861,Q9NW13,O95628,Q9BVJ6,P35269,P41223,Q86XP3,P46776,Q14137,O95400,Q14690,Q6P2E9,P62857,P39019,P55769,Q9BUQ8,Q8WVM0,Q9Y6M1,Q9NV06,Q92945,Q02878,Q99547,O15213,P62753,P23588,Q9HAU5,Q13151,P62273,P46777,Q9H3H1,Q96FX7,P05387,Q9UHI6,Q9BZI7,Q92499,P51991,P33240,O60828 145 +Eukaryotic translation elongation 0.4705684603301419 4.04993375276103 5.1232134299805665e-05 0.0696439590936373 0.0103122967469182 78 P62913,P83731,P61247,P26373,P50914,P62917,P84098,P62841,P62861,Q02878,P47914,P46776,P46778,P62753,P61254,P62424,P62750,P62273,P62081,P62899,P62857,P46777,P39019,P46779,P61353,P46782,P62263,P83881,P36578,P05387,P40429 31 +Response of eif2ak4 gcn2 to amino acid deficiency 0.4571588005342902 3.9234599205013545 8.728629200249749e-05 0.1157290451136371 0.0142888783752581 79 P62913,P83731,P61247,P26373,P50914,P62917,P84098,P62841,P62861,Q02878,P47914,P46776,P46778,P62753,P61254,P62424,P62750,P62273,P62081,P62899,P62857,P46777,P39019,P46779,P61353,P46782,P62263,P83881,P36578,P05387,P40429,P62847 32 +Nonsense mediated decay nmd 0.4492007564855004 3.7277278884318577 0.0001932138264981 0.2383472874736985 0.0272238281535927 89 P62913,P83731,P26373,P61247,P50914,P62917,P84098,P62841,P62861,Q02878,P47914,P46776,P46778,P62753,P61254,P62424,Q9HAU5,P62750,P62273,P62081,P62899,P62857,P46777,P39019,P46779,P61353,P46782,P62263,P11940,P83881,P36578,P05387,Q15287,Q9BZI7,P40429 35 +Cellular response to starvation 0.4390411097107279 3.5319291252587415 0.0004125399080434 0.4408786032492331 0.0484390608694367 92 P36543,P62913,P83731,P26373,P61247,P50914,P62917,P84098,P62841,P55735,P62861,Q02878,P47914,P46776,P46778,P62753,P61254,P62424,P62750,P62273,Q9Y5K8,P62081,P62899,P62857,P46777,P39019,P46779,P61353,P46782,P62263,P83881,P36578,P05387,P42345,P40429,Q96EE3 36 +Selenoamino acid metabolism 0.434039640094537 3.47329119676247 0.0005141172246809 0.5154707337465804 0.0557223976596536 91 P62913,P83731,P61247,P26373,P50914,P62917,P84098,P62841,Q16881,P62861,Q02878,P47914,P46776,P46778,P62753,P61254,P62424,P62750,P62273,P62081,P62899,P62857,P46777,P39019,P46779,P61353,Q12904,Q96I15,P46782,P62263,P83881,P36578,P05387,P40429,P62847 35 +Apoptotic execution phase 0.5880289396111436 3.428419126998773 0.0006071073869964 0.5750033861896937 0.0611010220198551 30 Q13177,P16403,Q13464,P10412,Q07157,P07305,P26583,P16402,Q9UKV3,Q9UDY2,Q16625,Q9UJU6,P02545,P35611,Q13813,P20700,Q15149 17 +Signaling by alk in cancer 0.5155081152816543 2.950418510678274 0.0031734374506624 0.9886493835710776 0.1039854271624046 35 Q14203,P12270,O43815,P62753,P35579,P51608,Q9HC35,O00291,Q9P2E9,Q8IWJ2,P33176,P18206 12 +Mrna splicing 0.4470520936117546 2.9057395671887396 0.0036638625767597 0.9943260097664096 0.106976631383135 153 Q9Y3C6,Q9BXP5,Q13573,P13984,P24928,P84103,Q9Y3B4,P38159,Q15637,Q01081,Q9H2H8,P09012,Q6UX04,Q05048,P26599,Q9P013,Q8IX12,Q13243,O75400,P52272,Q13435,Q8WYA6,P62314,Q86V81,P08579,P35269,P41223,O43290,Q86XP3,P62304,Q00839,Q8WUA2,O95400,Q08170,Q9ULR0,P08621,P16383,Q96I25,Q99459,Q13151,Q9C0J8,Q92917,Q92733,Q7L014,O43395,Q9UQ35,Q15287,Q01130,O75494,Q9Y2W2,P55769,Q9BZI7,Q9BUQ8,Q05519,P51991,P33240,O75937,O60828,O94992,P11142,Q6UN15,Q15459 62 +Sumoylation 0.3829642903833387 2.8441624633102127 0.0044528336969407 0.9981416251671348 0.1175195265519898 82 Q96ST3,Q9UKX7,P11387,P49790,Q14676,P62805,Q9UER7,P12270,P61956,P55735,Q7Z3B4,P35658,Q9NQS7,P06748,Q9UQE7,P26358,Q99496,P54132,Q8NFH5,Q15424,P09874,P14373,Q9UBT2,Q96EE3,Q14683 25 +Reproduction 0.5257248944382776 2.8042107904953344 0.0050439916711111 0.999195241680511 0.1201489783441935 27 P16104,Q9UQE7,Q14683,O60934,P54652,P02545,P54132,Q9NYB0,Q92878,Q9BTC0,P62805 11 +Apoptotic cleavage of cellular proteins 0.6176045344274924 2.768564335270743 0.0056303868183027 0.9996493187084304 0.1247313383181591 19 Q13464,Q07157,Q9UDY2,Q9UKV3,Q16625,Q05655,Q9UJU6,P02545,P35611,Q13813,P20700,Q15149 12 +Sema4d in semaphorin signaling 0.8120379202674921 2.760926594486162 0.0057637629484079 0.999709711843218 0.1247313383181591 8 P35579,Q13464,Q7Z406,Q9NWH9 4 +Rho gtpases activate paks 0.726177779352139 2.7564848520283207 0.0058426318871529 0.999740411136128 0.1247313383181591 12 P21333,O14974,Q7Z406,P35580,P35579 5 +Meiosis 0.5328878698648082 2.7467385759557197 0.0060191090878405 0.9997978602757004 0.1265809657427957 26 P16104,Q9UQE7,Q14683,O60934,P54652,P02545,P54132,Q9NYB0,Q92878,Q9BTC0,P62805 11 +Dna damage telomere stress induced senescence 0.6475223258807477 2.720515729658298 0.00651801707671 0.9999003600252556 0.1294996482628336 15 P16403,P16104,P10412,P07305,P16402,O60934,Q9NYB0,Q92878,P62805 9 +Chromatin modifying enzymes 0.3864292814396598 2.6839156490069493 0.0072765462427533 0.9999660335592144 0.1334143514236676 75 Q15014,Q96GM5,Q9NPF5,Q14839,Q86YP4,Q92922,Q12824,P11802,O95983,P62805,Q9HAF1,Q9H9T3,O75446,Q16576,Q8IUF8,O75528,Q969G3,Q8WXI9,Q9UBU8,O14497,Q9Y2K7,P16104,Q15910,Q9UPT9,Q92925,Q9NPA8,Q7LBC6,Q96L73,O94776,Q86U86,Q8TAQ2,Q15291,P51610,Q68CP9,Q9H7B4,Q13330,Q15906 37 +Homology directed repair 0.4522863360809306 2.584131869671157 0.0097624460164189 0.9999990073316996 0.1677473955748087 43 P16104,P61088,P09874,O60934,P49916,P61956,Q9UNS1,P18887,Q14676,P54132,Q92878,Q9NRF9,P39748 13 +Hcmv infection 0.4074373245208491 2.567676757067171 0.010238257728061 0.999999495682662 0.171188892925778 63 Q9UKX7,Q9UQN3,Q9Y3E7,P49790,Q9HD42,Q9UN37,P62805,Q9UER7,P12270,Q16576,P55735,Q7Z3B4,P35658,Q13409,Q9H444,Q15910,Q8NFH5,O43237,Q96EE3 19 +Hdr through mmej alt nhej 0.7705814257164493 2.5537228653690813 0.0106578047848882 0.999999722499588 0.171188892925778 8 P09874,O60934,P18887,Q92878,P39748 5 +Apoptosis induced dna fragmentation 0.744692092578094 2.542568295305835 0.0110041093866335 0.999999830553631 0.1722754458418518 9 P16403,P10412,P26583,P16402 4 +Rho gtpases activate rocks 0.7176432554214096 2.528386877339607 0.0114588006443514 0.999999911358584 0.1751310142421261 10 P35579,Q13464,Q7Z406,O14974 4 +Sensory processing of sound 0.5823613057901843 2.5161209135835527 0.0118654468094292 0.9999999503561798 0.1751420775231468 19 Q9Y2J2,P15311,Q13813,Q01082,O00159,P35579,P47755 7 +Eukaryotic translation initiation 0.3830066356534871 2.503282100200894 0.0123047423363726 0.9999999734684464 0.177372559422084 103 P62913,P83731,P26373,P50914,P62917,P84098,P62841,P62861,Q02878,P47914,P46778,P62753,P23588,P61254,P62424,P62750,Q15056,P62273,P62081,O60841,P62899,P62857,P46777,P39019,P46779,P61353,P46782,P62263,P11940,P05387,P40429 31 +Endosomal sorting complex required for transport escrt 0.6020902812508648 2.471080575666483 0.0134705463460473 0.999999994975777 0.186580510927988 16 Q9NP79,Q9H444,Q9UQN3,Q9Y3E7,O14964,Q9UN37 6 +Dna double strand break repair 0.4087514071391789 2.4419889236667687 0.0146065947643667 0.9999999990091708 0.1895703014450682 56 P16104,P61088,P09874,Q04323,O60934,Q99496,P49916,P61956,Q9UNS1,P18887,Q14676,P54132,Q92878,Q9NRF9,Q9UIG0,P39748 16 +Semaphorin interactions 0.561807711450796 2.43286647873207 0.0149798237048877 0.9999999994189908 0.1901492936953764 20 Q13177,Q13464,Q9NWH9,Q9BPU6,Q7Z406,P35580,O75116,P35579,Q9Y490 9 +Meiotic synapsis 0.593115349205373 2.41002925486686 0.0159512414053022 0.999999999855318 0.1954373838267031 16 P16104,Q9UQE7,Q14683,P54652,P02545,Q9BTC0,P62805 7 +Met promotes cell motility 0.694256279418185 2.399324966168192 0.016425330482191 0.999999999926627 0.1995111262879934 10 Q9NWH9,P07942 2 +Rna polymerase ii transcription termination 0.4191598355264919 2.361118724720271 0.0182198965409596 0.9999999999944018 0.2104248707066573 47 O75152,Q05048,Q13243,Q86V81,P62304,Q08170,Q9BY77,Q13769,Q9C0J8,P82979,Q15287,Q01130,Q9BZI7,Q9Y3Y2,Q05519,P33240,Q6UN15,O94992,P84103,Q01081 20 +Transport of mature transcript to cytoplasm 0.3847049045637874 2.3391546046830047 0.0193274335131836 0.9999999999988588 0.2178588305606063 66 O75152,Q9UKX7,P49790,P12270,P55735,Q86V81,Q7Z3B4,P35658,Q08170,Q9BY77,Q13769,Q9C0J8,Q8NFH5,P82979,Q15287,Q01130,Q9BZI7,Q9Y3Y2,Q05519,Q6UN15,Q96EE3 21 +Epha mediated growth cone collapse 0.7727837827782291 2.305557856881328 0.0211353503938118 0.9999999999999152 0.2276204721580361 7 P35579,Q13464,Q7Z406 3 +Hsf1 dependent transactivation 0.6056280188035454 2.297973637281691 0.0215632896113888 0.9999999999999544 0.2276204721580361 14 P0DMV9,P42345,O75190,P54652,P50454,P25685,P11142 7 +Processing of capped intron containing pre mrna 0.4274010519511819 2.282650441018733 0.0224509672153796 0.9999999999999872 0.2311258949350423 195 Q9Y3C6,O75152,Q9UKX7,Q13573,P13984,P24928,P38159,Q15637,P49790,Q9H2H8,P09012,Q6UX04,Q05048,P26599,Q9P013,Q8IX12,P12270,O75400,P52272,Q13243,Q13435,Q8WYA6,P55735,P62314,Q86V81,Q7Z3B4,P08579,P35269,P35658,O43290,Q86XP3,Q8WUA2,O95400,Q08170,Q9ULR0,P08621,P16383,Q99459,Q13151,Q9BY77,Q13769,Q9C0J8,Q92917,Q8NFH5,Q92733,Q7L014,O43395,Q9UQ35,Q15007,P82979,Q01130,Q15287,O60828,O75494,Q9Y2W2,P55769,Q9BZI7,Q9Y3Y2,Q9BUQ8,Q05519,P51991,Q15459,O75937,P33240,O94992,P11142,Q6UN15,Q96EE3 68 +Rho gtpases activate cit 0.6958766704454141 2.282279375727279 0.0224728513882901 0.9999999999999876 0.2311258949350423 9 P35579,Q7Z406,O14974 3 +Sumoylation of transcription cofactors 0.6214840670673358 2.2643792414244577 0.0235507996047057 0.9999999999999974 0.234107933352946 13 Q96ST3,Q9UER7,Q15424,Q99496,P61956 5 +Influenza infection 0.3895928415181486 2.2641136152964263 0.0235671277855586 0.9999999999999974 0.234107933352946 128 Q9UKX7,P13984,P24928,P62913,P83731,P49790,P26373,P50914,P62917,P84098,P12270,P62841,P09496,P55735,P62861,Q02878,Q7Z3B4,P47914,P35658,P46778,P62753,P61254,P62424,P62750,P62273,P62081,P62899,P62857,P46777,P39019,P46779,P61353,Q8NFH5,P46782,P62263,P09874,Q12849,P05387,P40429,Q96EE3 40 +Hats acetylate histones 0.477778543895229 2.2623235560661654 0.0236774200732099 0.9999999999999978 0.234107933352946 26 Q15014,Q9HAF1,Q16576,Q9UPT9,Q9NPF5,O75528,Q9NPA8,P51610,Q15906 9 +Hcmv late events 0.4252861493105394 2.2560021691086707 0.0240704952875674 0.9999999999999988 0.234107933352946 42 Q8NFH5,Q9H444,P12270,Q9UKX7,Q9UQN3,Q9Y3E7,P55735,P49790,Q9HD42,P35658,Q9UN37,Q96EE3,P62805 13 +Met activates ptk2 signaling 0.8801122931196799 2.255658669573114 0.0240920158525033 0.9999999999999988 0.234107933352946 5 Q9NWH9,P07942 2 +Dna double strand break response 0.528323893705613 2.2480100237383303 0.0245755507570895 0.9999999999999994 0.2364536654128722 21 P16104,Q04323,O60934,Q99496,Q14676,P61088,Q92878,Q9UIG0 8 +Late endosomal microautophagy 0.6387758819074643 2.2465461320427913 0.0246690481303706 0.9999999999999994 0.2364536654128722 12 O60664,Q9H444,Q9UQN3 3 +Constitutive signaling by aberrant pi3k in cancer 0.805866868750706 2.2282843576492044 0.0258615587711403 1.0 0.2445566195203811 6 P84095,Q9NWH9 2 +Cell cell communication 0.4566687592144177 2.21340217456658 0.0268699308814257 1.0 0.2520107913170725 29 Q9BY67,Q9Y5K6,P19022,Q14315,Q8N3R9,Q13813,Q01082,P21333,Q15149 9 +Budding and maturation of hiv virion 0.6129877249459991 2.211408756824696 0.0270075439949453 1.0 0.2520107913170725 13 Q9NP79,Q9H444,Q9UQN3,Q9Y3E7,Q9UN37 5 +G alpha 12 13 signalling events 0.6816963457155246 2.2053256626540367 0.0274312502894165 1.0 0.2542804714328148 9 Q13464,Q12802,Q92888,O75116,Q92974 5 +Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.5886485061426869 2.1876959405411394 0.0286917579686187 1.0 0.257628464608764 14 P16104,P84243,Q16576,Q8WXI9,Q14839,Q13185,Q86YP4,O94776,O95983,P62805 10 +Rho gtpases activate ktn1 0.7472178025183228 2.1812254415651435 0.029166745938848 1.0 0.257628464608764 7 Q86UP2,P84095 2 +Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.5585615714996207 2.1715697225066237 0.029888132841632 1.0 0.2615675725084445 16 Q96GM5,Q86U86,Q92925,Q8TAQ2,Q99496,Q969G3,Q68CP9,Q92922,P67870,Q12824,O14497 11 +Mitochondrial translation 0.3738686127465215 2.162854586173523 0.0305523656393891 1.0 0.265730143122835 65 Q96RP9,Q5T653,Q92665,Q9BYD2,Q9NQ50,Q9BRJ2,P52815,Q9Y3D9,Q9Y3B7,Q8TAE8,Q9BYN8,Q13405,P82912,Q96A35,Q9Y291,Q9Y2R9,Q9P015,Q14197,Q8IXM3,Q96GC5,Q9BYD3,P82650,P82673,Q6P1L8 24 +Attenuation phase 0.6374360643185487 2.154294025328184 0.0312171211307314 1.0 0.2677171240337193 11 P0DMV9,O75190,P54652,P50454,P25685,P11142 6 +Calnexin calreticulin cycle 0.650646689612941 2.153944574009929 0.0312445188000816 1.0 0.2677171240337193 10 P14314,O60858,Q9NYU2,P30101,Q13438 5 +Metabolism of folate and pterines 0.6913034520493578 2.1439755362657187 0.032034847008616 1.0 0.2719102375610842 8 P00374 1 +Rho gtpases activate pkns 0.5203835484177475 2.1182036671180704 0.0341578227605863 1.0 0.2864784063670603 20 P16104,O14974,Q7Z406,P35580,P35579 5 +Sema4d induced cell migration and growth cone collapse 0.7793116535588345 2.106517370466404 0.0351594358562397 1.0 0.2931339948014305 6 P35579,Q13464,Q7Z406 3 +Epigenetic regulation of gene expression 0.3901326333599761 2.097805179656514 0.0359223587836436 1.0 0.2939037688720805 49 Q96ST3,Q9UIF9,P84243,Q9UHR5,Q14839,Q86YP4,O15160,Q9NR30,O95983,Q9UIG0,P62805,Q16576,O75446,P17480,Q8WXI9,P16104,Q15910,Q9NY93,P26358,Q96EB6,Q13185,P32780,O94776,P18074,O00159,Q13330 26 +Sensory processing of sound by outer hair cells of the cochlea 0.5746740467722675 2.0960804683692733 0.0360750533168277 1.0 0.2939037688720805 14 Q9Y2J2,P15311,Q13813,O00159,P35579 5 +Alk mutants bind tkis 0.7264560973416115 2.0791024790669708 0.0376079323002382 1.0 0.2976942506237963 7 O00291,O43815,Q9HC35 3 +Negative regulation of the pi3k akt network 0.5339404647272334 1.998478782006851 0.0456647780273662 1.0 0.3354886688787637 16 P84095,Q9NWH9 2 +Hdacs deacetylate histones 0.5335642858936255 1.995814754472004 0.0459540902012785 1.0 0.3354886688787637 16 Q16576,O75446,Q8WXI9,Q86YP4,O94776,P62805 6 +Cell junction organization 0.5091225443920091 1.971532584263568 0.0486629897461843 1.0 0.3519077856747974 19 Q9BY67,P19022,Q14315,Q8N3R9,P21333,Q15149 6 +Rhobtb gtpase cycle 0.4284726385911409 1.961546627771368 0.0498152913131413 1.0 0.352623857156306 30 Q7Z6E9,Q13464,Q8N684,Q9UM54,Q5VTR2,Q96DH6,O43396,P38159,O75116,Q16543,Q9NYL9,P78371,P08238,Q8IYB3,P07900,P12814 16 +Positive epigenetic regulation of rrna expression 0.4275503135921562 1.9525227326049164 0.0508761747128985 1.0 0.3566394535844477 30 P16104,Q16576,O00159,Q8WXI9,Q13185,Q86YP4,O94776,O15160,Q9NR30,O95983,Q9UIG0,P62805 12 +Sumoylation of dna damage response and repair proteins 0.3746292300577516 1.9077938502026537 0.0564178659368606 1.0 0.3861126149774861 49 P12270,Q9UKX7,Q9UQE7,P09874,Q14683,Q99496,P61956,P55735,P49790,Q14676,P54132,P35658,Q96EE3,Q8NFH5 14 +Transcriptional regulation of white adipocyte differentiation 0.5649666111243985 1.9071354004982923 0.0565030561182853 1.0 0.3861126149774861 13 Q9NPJ6,Q71SY5,Q9Y2W1,Q14966,Q9NVC6,Q15648,P11802 7 +Cellular response to heat stress 0.3560101912383659 1.891764526144088 0.0585223617010322 1.0 0.3940239749707342 64 P0DMV9,O95757,P12270,Q9UKX7,P42345,O75190,P54652,Q99543,P50454,P25685,P55735,Q96EB6,P49790,P55072,Q7Z3B4,P35658,Q96EE3,Q8NFH5 18 +Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.4167816635124151 1.888150719593095 0.0590057194597763 1.0 0.3940239749707342 32 Q13409,P0DMV9,Q14203,Q9BVA1,P31948,P54652,P31689,P25685,O43237,P08238,P47755,Q9Y6G9,P11142 13 +Regulation of tp53 activity through acetylation 0.5228413939232746 1.8801920502623308 0.0600819086676165 1.0 0.3993179684559986 15 Q9HAF1,Q16576,Q13526,Q8WXI9,Q86YP4,O94776 6 +Diseases of dna repair 0.5599958653374209 1.8751931753131643 0.0607661527222527 1.0 0.4019695266932117 13 Q92878,P20585 2 +Hcmv early events 0.3685340324361795 1.8729651643829812 0.0610731955697958 1.0 0.4021127689618801 50 Q9UER7,Q13409,Q8NFH5,P12270,Q9UKX7,Q16576,Q15910,O43237,P55735,P49790,Q7Z3B4,P35658,Q96EE3,P62805 14 +Regulation of hsf1 mediated heat shock response 0.3624082154864931 1.8586905816148265 0.0630710092343238 1.0 0.4105175854608356 57 P0DMV9,O95757,P12270,Q9UKX7,O75190,P54652,Q99543,P50454,P25685,P55735,Q96EB6,P49790,Q7Z3B4,P35658,Q96EE3,Q8NFH5 16 +Smooth muscle contraction 0.557265438570995 1.857614435298968 0.0632237871149761 1.0 0.4105175854608356 13 Q13177,Q9Y490,P04083,Q05682,O60504,P18206 6 +Depolymerisation of the nuclear lamina 0.6364259382621757 1.850327890732007 0.0642663051139258 1.0 0.4123298903416784 8 Q8NC56,Q9Y2U8,P02545,P20700,P50402 5 +Non integrin membrane ecm interactions 0.6350600483936155 1.842923327725267 0.0653402057942291 1.0 0.4158498842534678 8 P07942 1 +Processing of dna double strand break ends 0.4192935494284619 1.8373166309012532 0.0661631661483443 1.0 0.4158498842534678 28 P16104,O60934,P61956,Q9UNS1,Q14676,P61088,P54132,Q92878 8 +Nrage signals death through jnk 0.6334494041155486 1.83418637219547 0.0666263336489165 1.0 0.4158498842534678 8 Q12802,Q92888,Q9NY61,Q12979,Q92974 5 +Laminin interactions 0.7713272842938206 1.7838159689454711 0.0744535738567662 1.0 0.4504659992951857 5 P07942 1 +Rna polymerase i transcription 0.4147659148059766 1.7795585317376863 0.0751482378212897 1.0 0.4504659992951857 27 P16104,P18074,P84243,Q16576,P17480,Q8WXI9,Q14839,Q13185,Q86YP4,O94776,O15160,O95983,Q13330,P32780,P62805 15 +Nonhomologous end joining nhej 0.4965282108426137 1.7309515945360554 0.0834603982491137 1.0 0.4552768782120915 16 P16104,O60934,Q14676,P61088,Q92878 5 +Regulation of pten gene transcription 0.4379857034958919 1.7260719586664972 0.0843344678590176 1.0 0.4552768782120915 24 Q15910,Q16576,P42345,Q99496,Q8WXI9,Q86YP4,O94776 7 +Rhobtb3 atpase cycle 0.757178584852622 1.7210609322228585 0.0852397676189857 1.0 0.4584077579204235 5 O60664 1 +Muscle contraction 0.4052649119701997 1.6882487933514407 0.0913634803624385 1.0 0.4799369329726196 27 Q13177,Q9Y490,P04083,Q05682,P20020,Q9NYL9,P05026,O60504,P18206 9 +Meiotic recombination 0.5291825820311271 1.6755646129771804 0.093823505098197 1.0 0.4886104086808752 13 P16104,O60934,P54132,Q92878,P62805 5 +Translation of replicase and assembly of the replication transcription complex 0.6430971225885043 1.6595133150690788 0.0970123998294545 1.0 0.4936680812982519 7 Q9H444,Q9UQN3 2 +Transcriptional regulation by e2f6 0.5430958110763932 1.6585673306897946 0.0972030094324176 1.0 0.4936680812982519 12 O00311,Q15910,Q16576,Q13185 4 +Srp dependent cotranslational protein targeting to membrane 0.3219891003511585 1.6575802486974474 0.0974022190212307 1.0 0.4936680812982519 94 P62913,P83731,P26373,P50914,P62917,P84098,P62841,P62861,Q02878,P47914,P46778,P62753,P61254,P62424,P62750,P62273,P62081,P62899,P62857,P46777,P39019,P46779,P61353,P46782,P62263,P05387,Q9UNL2,P40429 28 +Transcriptional activation of mitochondrial biogenesis 0.525794639414209 1.6534624179142672 0.0982367886935127 1.0 0.4961133880615032 13 Q8WVM0,Q04837,Q00059,P51610,Q15648,P48735 6 +Downregulation of smad2 3 smad4 transcriptional activity 0.7381075992912769 1.6360575257867835 0.1018275484499804 1.0 0.5024184382269389 5 Q13573 1 +Formation of senescence associated heterochromatin foci sahf 0.5968874897500066 1.6343522175452114 0.1021849151852793 1.0 0.5024184382269389 8 P16403,P10412,P16402 3 +Receptor type tyrosine protein phosphatases 0.8869900771775089 1.6276994854564724 0.1035886222712469 1.0 0.5036891597918486 2 P10586 1 +Hdms demethylate histones 0.5956095295368523 1.6273199309333335 0.1036691670260014 1.0 0.5036891597918486 8 Q7LBC6,Q9Y2K7 2 +Flt3 signaling in disease 0.6752214590793076 1.6159112382352925 0.1061135054799473 1.0 0.5068268787160876 6 Q9UBW7,Q92614 2 +Signaling by fgfr1 in disease 0.5356179304719868 1.61154298328472 0.107061426524321 1.0 0.5086724310594513 12 Q9UBW7 1 +Signaling by met 0.4409886967578697 1.6095322148849651 0.1075000167073698 1.0 0.5086724310594513 22 P40818,Q9NWH9,P07942 3 +Neurexins and neuroligins 0.556828528958443 1.6069976902191625 0.1080548747949969 1.0 0.5086724310594513 10 Q9Y2J2,Q96HC4,O43491 3 +Sumoylation of dna replication proteins 0.3735797993611248 1.595897336277303 0.110511716353852 1.0 0.513897717302236 38 P12270,Q9UKX7,P11387,P61956,P55735,P49790,P35658,Q9NQS7,Q96EE3,Q8NFH5 10 +Nuclear events stimulated by alk signaling in cancer 0.5307109871427842 1.580624496515209 0.1139639213212393 1.0 0.5264759512840205 12 P33176,P51608,Q9HC35,P62753 4 +Rrna processing 0.3754647966201011 1.5788190647339946 0.114377564392194 1.0 0.5266600922503314 172 Q8WVM0,O60832,P62913,P46087,P83731,Q2NL82,Q9NV06,Q9HC36,Q9NR30,P26373,P61247,P50914,P62917,P84098,O43709,P62841,Q9H6R4,P62861,Q02878,Q9NW13,P47914,Q9BVJ6,Q99547,P46776,P46778,O15213,P62753,Q14137,Q14690,Q9NY93,Q8IY81,P62424,Q9NPE3,P61254,P19338,P62750,Q969X6,Q99848,O43818,P62273,P78316,P62081,P62899,P62857,P46777,P39019,P46779,Q9ULX3,P61353,P46782,P62263,P83881,P36578,O00566,P05387,P55769,Q96GA3,Q14692,P40429,O75691 60 +Met activates rap1 and rac1 0.6641749442177528 1.5627989024308089 0.118099902448574 1.0 0.5420285425082764 6 Q96N67,P46108,Q9NWH9 3 +Fgfr1 mutant receptor activation 0.5376674119828205 1.5547912308729386 0.1199957982866024 1.0 0.5448463035899708 11 Q9UBW7 1 +Potential therapeutics for sars 0.3637138848768791 1.541534254867615 0.1231868126273709 1.0 0.5510165682284626 41 P62942,Q13464,Q16576,O75446,O60885,Q8WXI9,Q86YP4,P05026,O75116,O95983,Q9NZI8,O94776 12 +Mitotic prophase 0.3325489901997284 1.529415006356709 0.1261615946306364 1.0 0.5572466671929993 62 Q8NC56,Q9UKX7,P49790,P50402,P62805,P12270,Q9NTJ3,Q9Y2U8,P55735,Q7Z3B4,P35658,P16104,Q14980,P02545,P20700,Q9H8Y8,Q8NFH5,P42167,P49792,Q08379,O95347,Q96EE3 22 +Apoptotic cleavage of cell adhesion proteins 0.6525289264726488 1.5066460881848518 0.1319013972305338 1.0 0.5697847342775068 6 Q07157,Q9UDY2 2 +Prc2 methylates histones and dna 0.5387658193924648 1.4993434668348655 0.1337845514871118 1.0 0.5697847342775068 10 P16104,Q15910,Q16576,P62805 4 +Recognition and association of dna glycosylase with site containing an affected purine 0.7599896751042335 1.4904441313311374 0.13610749607066 1.0 0.5697847342775068 4 P16104,P62805 2 +Sealing of the nuclear envelope ne by escrt iii 0.4842451282878142 1.4873166152735846 0.1369312082211013 1.0 0.5697847342775068 14 Q9H444,Q8NC56,Q9UQN3,Q9Y3E7,P53990,Q9UN37 6 +Rhobtb1 gtpase cycle 0.4399870595521333 1.4859852056062623 0.1372830342552073 1.0 0.5697847342775068 20 Q7Z6E9,Q13464,Q8N684,Q9UM54,Q5VTR2,O43396,P38159,P78371,O75116,Q8IYB3 10 +Caspase mediated cleavage of cytoskeletal proteins 0.704434232421723 1.4849933772484911 0.1375455784805184 1.0 0.5697847342775068 5 P35611,Q15149,Q13813 3 +Signaling by cytosolic fgfr1 fusion mutants 0.5516038442354623 1.4744346871802747 0.1403645908175927 1.0 0.5709105841730507 9 Q9UBW7 1 +Pyroptosis 0.567926877538185 1.474366716942265 0.1403828807335156 1.0 0.5709105841730507 8 Q9H444,Q9UQN3 2 +Signaling by flt3 fusion proteins 0.7010662426515268 1.4698292340642554 0.1416080093725571 1.0 0.5717068344009542 5 Q9UBW7,Q92614 2 +Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.5626763599189639 1.4452452900322423 0.1483889991364708 1.0 0.5889901202178665 8 P09874,Q13573,P28482,P27361,Q9UPN9 5 +Sirt1 negatively regulates rrna expression 0.6951480480857881 1.443164253871888 0.1489742065481545 1.0 0.5889901202178665 5 P62805,P16104,Q96EB6 3 +Sumoylation of rna binding proteins 0.3684904565954306 1.4375642759640177 0.1505577231899342 1.0 0.5918416459398868 34 P12270,Q9UKX7,Q99496,P61956,P55735,P49790,P35658,Q96EE3,Q8NFH5 9 +Hsf1 activation 0.4763550883977869 1.4332711928452144 0.1517803511113682 1.0 0.5918416459398868 14 P0DMV9,O75190,P50454,P25685,P55072 5 +Sumoylation of chromatin organization proteins 0.3610369937692968 1.430815145875465 0.1524832011168446 1.0 0.5918416459398868 37 Q8NFH5,P12270,Q9UKX7,Q99496,P61956,P55735,P49790,Q7Z3B4,P35658,Q96EE3,P62805 11 +Copi independent golgi to er retrograde traffic 0.3762096732147462 1.4300922457795089 0.1526905454413867 1.0 0.5918416459398868 29 Q13409,Q13561,Q14203,Q9BVA1,Q8TD16,P68402,O43237,P47755,Q9Y6G9,Q15042 10 +Negative regulation of met activity 0.559287888136427 1.4264374118757834 0.1537421210973863 1.0 0.5918416459398868 8 P40818,Q9NWH9 2 +Regulation of expression of slits and robos 0.3349570273455597 1.4157982647566207 0.1568345777971203 1.0 0.5965592021382601 125 O00233,P62913,P83731,P26373,P50914,P62917,P84098,P62841,P62861,Q02878,P47914,P46778,P62753,P61254,P62424,Q9HAU5,P62750,P62273,P62081,P62899,P62857,P46777,P55036,P39019,P46779,P61353,P46782,P62263,P11940,P83881,P05387,P17980,Q9BZI7,P40429 34 +Inlb mediated entry of listeria monocytogenes into host cell 0.6326816726483923 1.410647512595656 0.1583485745917028 1.0 0.5965592021382601 6 Q99961,Q9NWH9,O14964 3 +Metabolism of cofactors 0.555623560795889 1.4060875461949385 0.1596981299928876 1.0 0.6000391070932767 8 P00374 1 +Transport of mature mrnas derived from intronless transcripts 0.3557523029202935 1.400997465102506 0.1612148311333343 1.0 0.6041268539012449 38 P12270,P49790,Q86V81,P35658,Q9C0J8,Q8NFH5 6 +Er quality control compartment erqc 0.6853227551027077 1.398850576623291 0.1618577959810136 1.0 0.6049274125656453 5 O60858,Q13438 2 +Rhobtb2 gtpase cycle 0.4285952784886098 1.395010864879629 0.1630125632322132 1.0 0.6058660464344475 20 Q9UM54,Q96DH6,O43396,P38159,Q16543,Q9NYL9,P78371,P08238,Q8IYB3,P07900,P12814 11 +Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.8657292528260261 1.393864350228842 0.1633585714270671 1.0 0.6058660464344475 3 P18887,Q96T60 2 +Sensory perception 0.3835870071109898 1.3923087237456395 0.1638289309379166 1.0 0.6058660464344475 26 Q9Y2J2,P15311,Q13813,Q01082,O00159,P35579,P47755 7 +Deposition of new cenpa containing nucleosomes at the centromere 0.500117064729105 1.3870253951957026 0.1654340192345706 1.0 0.6086071360352744 12 P06748,P16104,Q96T23,Q16576,Q9H3R5 5 +Runx1 regulates expression of components of tight junctions 0.8299338478500542 1.3852055426337124 0.1659896263929243 1.0 0.6090608947594542 2 Q07157 1 +Cell extracellular matrix interactions 0.5514400157861701 1.3828423872044682 0.1667131988896923 1.0 0.6101270058066924 8 Q14315 1 +Regulation of innate immune responses to cytosolic dna 0.7319360176502889 1.3717273082590071 0.1701483438936579 1.0 0.6210855350936892 4 Q13049,P19474,Q9NZI8 3 +Sumoylation of sumoylation proteins 0.3698128813528859 1.3669191712136952 0.1716506421752508 1.0 0.6241603710255986 29 P12270,Q9UKX7,P61956,P55735,P49790,P35658,Q96EE3,Q8NFH5 8 +Notch3 intracellular domain regulates transcription 0.8517124155100768 1.3393099246379874 0.1804697991487835 1.0 0.6384847915095456 3 Q13573 1 +N glycan trimming in the er and calnexin calreticulin cycle 0.4370823215706123 1.3313923406877366 0.1830599483267359 1.0 0.6384847915095456 17 P54727,P14314,Q04323,O60858,Q9NYU2,P30101,Q13438,P55072,Q14697 9 +Pkmts methylate histone lysines 0.4455572509180563 1.3313569738371938 0.1830715796805226 1.0 0.6384847915095456 15 Q15910,Q16576,Q96L73 3 +Basigin interactions 0.5409302101905444 1.3244069378342471 0.1853679316856693 1.0 0.6446564338862213 8 P05026 1 +Sumoylation of ubiquitinylation proteins 0.3640979192501764 1.323238072060673 0.1857562187067465 1.0 0.6446564338862213 30 P12270,Q9UKX7,P14373,P55735,P49790,P35658,Q96EE3,Q8NFH5 8 +Notch4 intracellular domain regulates transcription 0.811742006615239 1.3079034982239148 0.1909060428562266 1.0 0.6520884806301465 2 Q13573 1 +Sensing of dna double strand breaks 0.7138602442776671 1.2951214588053 0.1952783333862453 1.0 0.655157156643721 4 Q92878 1 +Inhibition of dna recombination at telomere 0.4702895014009459 1.2887171153717565 0.1974964500590468 1.0 0.6578546055158321 13 P16104,Q9UER7,P24928,P62805 4 +Signaling by pdgfr in disease 0.6605380784424956 1.2869210812274332 0.1981217966120572 1.0 0.6583811590245015 5 Q6UN15 1 +Rhou gtpase cycle 0.4132306524808311 1.2723005808885837 0.20326634228865 1.0 0.6652580691186422 20 Q9UM54,Q9NZM3,O14964,Q13813,P46940,Q01082,O96013 7 +Protein protein interactions at synapses 0.433466872245393 1.2720398141597604 0.2033589735232763 1.0 0.6652580691186422 16 O43491,Q9Y2J2,P10586,Q13136,Q96HC4 5 +Cell cell junction organization 0.5136638423780657 1.255723174400846 0.209216354020602 1.0 0.6738844480681786 9 Q9BY67,P19022,Q8N3R9 3 +Mecp2 regulates neuronal receptors and channels 0.5646900203017451 1.254988630472892 0.2094828873341818 1.0 0.6738844480681786 7 P51608,Q9NWH9 2 +Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0.6499578383337037 1.2391326407581702 0.2152963808122647 1.0 0.6832265778479303 5 P16104,P62805 2 +Sumoylation of transcription factors 0.5967229759808095 1.236204724717759 0.2163824749211289 1.0 0.6835939622508311 6 P42771,P61956,Q13330,Q12888 4 +Ncam signaling for neurite out growth 0.5957505518763911 1.2314863539335177 0.2181410173344011 1.0 0.6839336940929412 6 P28482,Q13813,Q01082,P27361,P62993 5 +Listeria monocytogenes entry into host cells 0.5241506231609556 1.2310850130830393 0.2182910701747513 1.0 0.6839336940929412 8 Q9NWH9 1 +Transcriptional regulation by the ap 2 tfap2 family of transcription factors 0.5945302802053729 1.2255657950984258 0.2203621162391489 1.0 0.6859714432371536 6 P06748,P10809,P46087,P25490 4 +Eph ephrin signaling 0.3562365622565459 1.2227314506568796 0.2214311439582847 1.0 0.6859714432371536 28 Q13464,P09496,Q7Z406,P35580,P35579 5 +Mecp2 regulates transcription of neuronal ligands 0.8211823413085679 1.2206562036808355 0.2222162166247534 1.0 0.6859714432371536 3 P51608 1 +Rhob gtpase cycle 0.355193905073751 1.2125749616656012 0.2252923665518014 1.0 0.6859714432371536 28 Q13464,Q12802,Q92888,P11274,Q07960,Q16513,Q9UDY2,Q9H0H5,Q86VI3,O75116,Q9H2G2,Q12979,Q92974,O60610 14 +Synthesis of pyrophosphates in the cytosol 0.7863836824696804 1.2004751488584429 0.2299548584844908 1.0 0.6859714432371536 2 Q13572 1 +Factors involved in megakaryocyte development and platelet production 0.3175795823661628 1.200362147462982 0.2299987230289302 1.0 0.6859714432371536 49 Q96ST3,P45973,P84243,Q99661,Q9BVA1,Q13572,Q9H0H5,Q02241,P27144,Q9H4M9,Q9Y496,Q14807,Q86Y91,Q96N67,Q96Q89,Q9UIJ7,P47755,P33176 18 +Kinesins 0.3981981789641645 1.1988481695420072 0.2305869884672704 1.0 0.6859714432371536 21 Q99661,Q9BVA1,O95239,Q9H0H5,Q02241,Q9Y496,Q14807,Q86Y91,Q96Q89,O00139,P33176 11 +Pi3k akt signaling in cancer 0.4563246056366165 1.1967572604749346 0.2314011813260759 1.0 0.6859714432371536 13 P84095,O43815,Q9NWH9 3 +Maturation of sars cov 1 spike protein 0.6401781635242043 1.1949907478966837 0.2320906449740523 1.0 0.6859714432371536 5 P26572,P14314,Q14697 3 +Egfr downregulation 0.5024750465162445 1.1912179306451325 0.2335680422174979 1.0 0.6859714432371536 9 Q99961,Q14155,Q9UBC2,O14964,P62993 5 +Recruitment of numa to mitotic centrosomes 0.330438156541993 1.1843069311935426 0.2362915861114054 1.0 0.6895834498095104 42 Q13409,Q13561,Q9UPN4,Q96CW5,Q14203,Q7Z460,Q9BVA1,Q14980,Q9BV73,Q15154,Q7Z4H7,Q96CS2,Q9BSJ2,O15078,Q14008,P23258 16 +Constitutive signaling by ligand responsive egfr cancer variants 0.684983721101085 1.1728497721582842 0.2408560546553477 1.0 0.6895834498095104 4 Q16543,P62993 2 +Constitutive signaling by egfrviii 0.684983721101085 1.1728497721582842 0.2408560546553477 1.0 0.6895834498095104 4 Q16543,P62993 2 +Signaling by egfr in cancer 0.684983721101085 1.1728497721582842 0.2408560546553477 1.0 0.6895834498095104 4 Q16543,P62993 2 +Nephrin family interactions 0.5136260711388968 1.1726131479086743 0.2409509744765463 1.0 0.6895834498095104 8 Q9Y5K6,P46940,Q13813,Q01082,P12814 5 +Hiv life cycle 0.2846230186492197 1.1623054808583826 0.2451114010925332 1.0 0.6948932880067996 87 Q9UKX7,Q9UQN3,Q9Y3E7,P13984,P24928,P49790,Q9UN37,P39748,Q9NP79,P12270,P29083,Q14241,P55735,Q7Z3B4,P43487,Q9NZZ3,P35658,Q9H444,Q8NFH5,O75475,P18615,Q96EE3 22 +Anchoring of the basal body to the plasma membrane 0.3300758482376093 1.1476342184976818 0.2511195974974298 1.0 0.7009957185089127 40 Q13409,Q9UPN4,Q14203,Q15051,Q9BV73,Q15019,Q14008,O15078 8 +Signaling by notch3 0.575358137128407 1.1326515400720054 0.2573606155730021 1.0 0.7054885356855254 6 Q15398,Q13573 2 +Regulation of glucokinase by glucokinase regulatory protein 0.3456797255040075 1.1201624200474216 0.2626445549788578 1.0 0.7147935669577042 28 P12270,Q9UKX7,P55735,P49790,P35658,Q96EE3,Q8NFH5 7 +Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.4888918121040105 1.1130819456258294 0.2656732369369095 1.0 0.7184905774359029 9 O60934,Q92878 2 +Resolution of d loop structures 0.4888918121040105 1.1130819456258294 0.2656732369369095 1.0 0.7184905774359029 9 O60934,Q92878 2 +Josephin domain dubs 0.7615766262403492 1.0960587985617811 0.2730530437487122 1.0 0.7272811694554546 2 P55072 1 +Condensation of prophase chromosomes 0.4628853315773023 1.0946968602061458 0.2736494646295566 1.0 0.7274945201189533 11 P16104,O95347,Q9NTJ3,P62805 4 +Transcriptional regulation by small rnas 0.3232783166826164 1.0728905653599197 0.2833202196317659 1.0 0.7355230556567411 40 P16104,Q8NFH5,P12270,Q9UKX7,P24928,P55735,P49790,P35658,Q96EE3,P62805 10 +Fceri mediated mapk activation 0.5294031751104932 1.0726362545405708 0.2834343515775239 1.0 0.7355230556567411 7 Q13177,P62993,P28482,P27361 4 +Interaction between l1 and ankyrins 0.6609443424852334 1.071485540937701 0.2839511686177554 1.0 0.7355230556567411 4 Q13813 1 +Nuclear import of rev protein 0.3358281854347859 1.0677883475822378 0.2856159954483988 1.0 0.7384090597922823 32 P06748,P12270,Q9UKX7,P55735,P49790,P35658,Q96EE3,Q8NFH5 8 +Antimicrobial peptides 0.6591848385683612 1.06409203248867 0.2872870098753102 1.0 0.7407071476500736 4 Q96JM3 1 +Cellular senescence 0.3181880730003426 1.0466645938350796 0.295254298951888 1.0 0.7550150766301456 42 P16403,P16104,P10412,Q15910,Q16576,P16402,O60934,Q92878 8 +Transport of the slbp dependant mature mrna 0.3330349607163539 1.0398413224699925 0.2984136273747295 1.0 0.7589617346046822 32 P12270,Q9UKX7,P55735,P49790,Q86V81,P35658,Q96EE3,Q8NFH5 8 +Transcriptional regulation of granulopoiesis 0.5214338705595957 1.0316874821891986 0.3022185433823112 1.0 0.7662765578800607 7 P16104,P11802,P84243,P62805 4 +Base excision repair 0.3319213438059406 1.0287234584938696 0.3036096432639792 1.0 0.7662765578800607 32 P16104,P09874,P49916,P18887,Q9NRF9,P39748,Q96T60,P62805 8 +Interactions of rev with host cellular proteins 0.3272302468235726 1.0281824207527452 0.3038640259985081 1.0 0.7662765578800607 35 P06748,P12270,Q9UKX7,P55735,P49790,P43487,P35658,Q96EE3,Q8NFH5 9 +Rrna modification in the nucleus and cytosol 0.2992240360113476 1.0278743436639977 0.3040089395705847 1.0 0.7662765578800607 57 O60832,P46087,Q9NV06,O43709,Q9H6R4,Q9BVJ6,O15213,P62753,Q14690,Q9NPE3,Q969X6,O43818,P78316,P62081,P62263,O00566,P55769,Q14692,O75691 19 +Nuclear pore complex npc disassembly 0.3338029733249808 1.023543098960385 0.3060511330366968 1.0 0.7686604410549194 30 P12270,Q9UKX7,P55735,P49790,P35658,Q96EE3,Q8NFH5 7 +Hdr through homologous recombination hrr 0.3437033521247882 1.020097144530866 0.3076823908835873 1.0 0.7686604410549194 26 Q92878,Q9NRF9 2 +Transcriptional regulation by mecp2 0.4013402234632642 1.016379112673442 0.3094488882252943 1.0 0.7691277179297502 15 Q9NWH9 1 +Degradation of the extracellular matrix 0.4548181561495829 0.9975330608230488 0.3185058345641529 1.0 0.7801651733861363 10 P11047,P07942 2 +Nuclear envelope breakdown 0.3134600770644077 0.9792560821493514 0.3274534644815303 1.0 0.7927524595437736 41 P42167,P12270,Q8NC56,Q9UKX7,P20700,Q9Y2U8,P55735,P02545,P49790,Q7Z3B4,P35658,P50402,Q96EE3,Q8NFH5 14 +Regulation of plk1 activity at g2 m transition 0.3111788420123226 0.9688576162024896 0.3326162348785182 1.0 0.7936783933056198 42 Q13409,Q9UPN4,O15078,O14974 4 +Ptk6 regulates proteins involved in rna processing 0.7307056229327406 0.967668055851488 0.3332101766274353 1.0 0.7936783933056198 2 P23246 1 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.4764411425223993 0.9674334743469518 0.3333273827950556 1.0 0.7936783933056198 8 P11047,P07942 2 +Formation of the beta catenin tcf transactivating complex 0.4419517866820799 0.967150407792018 0.3334688494229432 1.0 0.7936783933056198 11 P16104,Q15291,Q6P1J9,P62805 4 +Viral messenger rna synthesis 0.3167558172619041 0.957789251239009 0.3381690403857327 1.0 0.7969619893938921 37 P12270,Q9UKX7,P13984,P24928,P55735,P49790,P35658,Q96EE3,Q8NFH5 9 +Oxidative stress induced senescence 0.3825843020771851 0.9573881660706848 0.3383713692417878 1.0 0.7969619893938921 18 P16104,P42771,Q15910,P84243,Q16576,Q99496,P27361,P11802,P62805 9 +Rna polymerase iii transcription 0.4282768623214008 0.9338309512838592 0.350391101033974 1.0 0.8126226391322493 12 P05455,O15160,Q9Y5Q8,O14802 4 +Inositol phosphate metabolism 0.5338793119786234 0.9333172622474524 0.3506561849484795 1.0 0.8126226391322493 6 Q13572,Q96PE3 2 +Chromosome maintenance 0.292634079197856 0.9271654591507532 0.3538406335985891 1.0 0.8159574842812423 53 P06748,Q9UER7,Q8WVB6,Q96T23,P16104,Q16576,O60832,Q9NPE3,P24928,Q9H3R5,P54132,P39748,P62805 13 +Ecm proteoglycans 0.5322644659055908 0.9256361091143728 0.3546351213256016 1.0 0.8159574842812423 6 P07942 1 +Rhoc gtpase cycle 0.3153310875741478 0.9238396011686816 0.3555698334625143 1.0 0.8159574842812423 36 P42167,Q13464,Q12802,Q92888,P11274,Q9UDY2,Q16513,P49257,Q9H0H5,Q86VI3,Q14739,O75116,Q9H2G2,P46940,Q12979,Q07960,O60610,O75955 18 +Dna repair 0.2980237790543606 0.9197144918851372 0.3577219775418749 1.0 0.816515977562815 118 Q04323,P24928,P20585,P18887,Q14676,Q99627,Q9UNS1,Q9UIG0,P39748,P62805,O60934,Q6P6C2,P61956,Q9H981,P61088,Q9NYB0,Q92878,P25490,P16104,Q9ULR0,Q9UBW8,Q99496,P54132,Q96T60,P09874,P49916,P55072,Q9NRF9 28 +Sumo is conjugated to e1 uba2 sae1 0.7421490074892538 0.9177224414343768 0.3587641957108243 1.0 0.816515977562815 3 P61956 1 +Processing and activation of sumo 0.7421490074892538 0.9177224414343768 0.3587641957108243 1.0 0.816515977562815 3 P61956 1 +Sumo is transferred from e1 to e2 ube2i ubc9 0.7421490074892538 0.9177224414343768 0.3587641957108243 1.0 0.816515977562815 3 P61956 1 +Rna polymerase i transcription initiation 0.3578170988536092 0.9167184219909624 0.3592902101411961 1.0 0.816515977562815 22 P18074,Q16576,P17480,Q8WXI9,Q14839,Q86YP4,O15160,O95983,P32780,O94776 10 +P130cas linkage to mapk signaling for integrins 0.7163726571113889 0.9088811653933246 0.3634128567510117 1.0 0.8166646174835336 2 Q9Y490 1 +Negative epigenetic regulation of rrna expression 0.3240296500197568 0.906979772683864 0.3644174938444324 1.0 0.8168366056748316 27 Q96ST3,Q9UIF9,P16104,P18074,P84243,O75446,P17480,P26358,Q9UHR5,Q96EB6,O15160,P32780,P62805 13 +Myogenesis 0.524420607981543 0.8884442118643949 0.3743018522773502 1.0 0.8298259173720661 6 P19022,O60271 2 +Shc1 events in erbb2 signaling 0.7108599779492779 0.8864431648715209 0.3753787678478932 1.0 0.8298259173720661 2 Q05655 1 +Cd28 dependent vav1 pathway 0.570466148880201 0.8837150515003943 0.3768500531350081 1.0 0.8309573159111524 5 Q13177 1 +Slc transporter disorders 0.3120127628990662 0.8731427993119705 0.3825852481029368 1.0 0.8357559915923068 35 P12270,Q9UKX7,P11166,P55735,P49790,P35658,Q96EE3,Q8NFH5 8 +Retrograde transport at the trans golgi network 0.3400899534192893 0.8672125893535024 0.3858255396203494 1.0 0.8391588383337767 24 O43752,Q9UIL1,Q9Y2V7,Q96CN9,O60664,Q8IWJ2 6 +Sars cov 1 infection 0.3702701844610351 0.8663972106621083 0.3862723730705124 1.0 0.8391588383337767 18 Q9H444,P14314,Q9UQN3,Q9Y3E7,P26572 5 +Mrna splicing minor pathway 0.3127049764503192 0.8650021217824192 0.387037624217184 1.0 0.8391588383337767 34 P62316,P35269,Q13435,P13984,P24928,Q01130,Q9Y3B4,P55769,P62314,Q9BUQ8,Q13247,O94906,P62304,Q86XP3 14 +Runx3 regulates p14 arf 0.7001102535832469 0.843000063054401 0.3992284085295412 1.0 0.8497172622630266 2 P25440 1 +Export of viral ribonucleoproteins from nucleus 0.314869104472292 0.840984216143987 0.4003567768517213 1.0 0.8505949965139374 30 P12270,Q9UKX7,P55735,P49790,P35658,Q96EE3,Q8NFH5 7 +Gap junction degradation 0.5126222777768505 0.8329211538751993 0.4048891984054918 1.0 0.8514759411243852 6 P09496 1 +Adherens junctions interactions 0.4814903666863322 0.8292414118397328 0.4069678160403787 1.0 0.8533716517755393 7 Q9BY67,P19022,P55196 3 +Loss of function of mecp2 in rett syndrome 0.5574851591055698 0.8270419812916785 0.4082132670665106 1.0 0.8533716517755393 5 P51608 1 +Rna polymerase iii transcription initiation from type 1 promoter 0.4181592485411634 0.8246447305213753 0.4095733184966965 1.0 0.8539993684226361 11 O14802 1 +Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 0.7157430383236814 0.8193271803787494 0.4125997690779304 1.0 0.857452912434814 3 P06748,P46087 2 +Signaling by moderate kinase activity braf mutants 0.4091513302156712 0.8163844199027401 0.4142803046763876 1.0 0.8596773921782478 12 Q9Y490 1 +Antigen presentation folding assembly and peptide loading of class i mhc 0.3579936454149273 0.8061969772301447 0.4201292813701136 1.0 0.8692542693839796 19 O95486,P01889,P55735,P30101,P30511,O15533,O95487,O94979 8 +Recruitment of mitotic centrosome proteins and complexes 0.2992711816820255 0.8050811561608544 0.4207728491002056 1.0 0.8693093026131814 39 Q13409,Q13561,Q9UPN4,Q96CW5,Q14203,Q7Z460,Q9BV73,Q15154,Q7Z4H7,Q96CS2,Q9BSJ2,O15078,Q14008,P23258 14 +Resolution of abasic sites ap sites 0.311172774733272 0.7987708786525219 0.4244232793642328 1.0 0.8731690648738495 29 P09874,P18887,Q9NRF9,P39748,Q96T60 5 +Signaling by fgfr in disease 0.3430200935281347 0.7979123593680909 0.42492135059921 1.0 0.8731690648738495 22 Q9UBW7,P11274,Q92614,P13984,P24928 5 +Mitotic prometaphase 0.2811948894756415 0.7946348792874288 0.4268259229663391 1.0 0.8731690648738495 108 Q96SN8,Q9UPN4,Q8NBT2,Q99661,Q12834,Q8WYP5,Q9BVA1,P23258,Q71F23,Q7Z4H7,Q96CS2,O00139,O15078,Q13561,Q9NTJ3,Q9Y266,Q9BV73,P55735,Q9BSJ2,Q14008,Q9NQS7,Q13409,Q96CW5,Q14203,Q9Y6D9,Q9UQE7,Q7Z460,Q14980,Q9H3R5,Q53HL2,Q9Y6G9,P49792,Q9HC35,O43237,Q15154,P67870,O95347,Q96EE3,Q14683 39 +Cd163 mediating an anti inflammatory response 0.7085194305056668 0.7927898571039619 0.4279002669570833 1.0 0.8731690648738495 3 P35579 1 +Map2k and mapk activation 0.4117382718578215 0.7868332098645052 0.4313795099558932 1.0 0.8736443178401939 11 Q9Y490 1 +Sars cov infections 0.2706744984559377 0.7864858267132055 0.4315829192954572 1.0 0.8736443178401939 69 Q13464,Q9UQN3,Q9Y3E7,O60885,Q86YP4,O95983,Q9NZI8,Q16576,O75446,Q8WXI9,Q14697,P62942,Q9H444,P26572,P05026,P08238,O94776,P14314,P55072,O75116 20 +Cation coupled chloride cotransporters 0.6857772877618735 0.7857941378764092 0.4319881014784623 1.0 0.8736443178401939 2 P55011 1 +Activation of anterior hox genes in hindbrain development during early embryogenesis 0.3461276504875202 0.7832944755065054 0.4334542066383031 1.0 0.8749520397449415 21 P16104,Q15910,Q16576,P24928,P62805,P25490 6 +Glycogen synthesis 0.5451034482758579 0.7735999101992913 0.4391674252188746 1.0 0.8802089646278725 5 P13807,P36871,Q96G03,P46976 4 +Signaling by egfr 0.3764993661988771 0.7586931879417605 0.4480361128139061 1.0 0.890384884280386 14 Q99961,Q14155,Q9UBC2,O14964,P78536,P62993 6 +Regulated necrosis 0.3512154468532106 0.7563679738090957 0.4494286040452551 1.0 0.8905747947608657 19 Q9H444,Q9UQN3 2 +Mtorc1 mediated signalling 0.402869460804047 0.7351831450530824 0.462227962593094 1.0 0.9012569300999944 11 P42345,P23588,P62753 3 +Phenylalanine metabolism 0.6717199558985831 0.7306050416834021 0.4650204316413739 1.0 0.9012569300999944 2 P09417 1 +Aggrephagy 0.3539458713096256 0.7251214103070603 0.4683775506281473 1.0 0.902238176655182 17 Q13409,O43237,P55072,P61088,Q9Y6G9 5 +Dna methylation 0.5333450922882516 0.7235065027277476 0.4693687604600769 1.0 0.902238176655182 5 P16104,P26358,P62805 3 +Estrogen dependent gene expression 0.2975162404134506 0.7170302245196613 0.4733554473929178 1.0 0.9046045568649412 34 P16104,Q9UQE7,Q14683,P13984,P24928,P25490,Q15648,P35269,P62805 9 +Regulation of tp53 activity 0.2742146157962931 0.715566989120162 0.4742587630406349 1.0 0.9046045568649412 57 Q9UER7,Q9HAF1,Q16576,O60934,P42345,Q13526,Q8WXI9,Q86YP4,P54132,Q9ULW0,P67870,Q92878,O94776 13 +Signaling by robo receptors 0.3008640317546214 0.7096061360918151 0.4779484134384395 1.0 0.908890178489496 140 O00233,P62913,P83731,P26373,P61247,Q13177,P50914,P62917,P84098,P62841,P62861,Q02878,P47914,P46776,P46778,P62753,P61254,P62424,Q9HAU5,P62750,P62273,P62081,Q8N8S7,P62899,P62857,P46777,P55036,P39019,P46779,P61353,P46782,P62263,P11940,P83881,P36578,P05387,Q15287,P17980,Q9BZI7,P40429,O96013 41 +Snrnp assembly 0.2853429078645146 0.6920384187761995 0.4889132025185072 1.0 0.9208279780674196 42 P12270,Q9UKX7,Q9UHI6,P62314,Q9H814,P55735,P49790,P35658,Q96EE3,Q8NFH5 10 +Rrna modification in the mitochondrion 0.6765784840073552 0.6779005873244928 0.4978347275759702 1.0 0.9208567619333018 3 Q8WVM0 1 +Rac1 gtpase cycle 0.2734763959899988 0.6766562658670692 0.4986240707900344 1.0 0.9208567619333018 49 Q13177,Q15758,Q8IZP0,A1A4S6,Q16513,P11274,Q86UP2,Q9H0H5,O96013,Q86VI3,Q9Y6W5,Q96N67,P46940,Q9UQB8,Q07960,Q13112,P50402 17 +Aurka activation by tpx2 0.285584772641728 0.6664296342803704 0.5051365261044705 1.0 0.9208567619333018 39 Q13409,Q13561,Q9UPN4,Q14203,Q7Z460,Q9ULW0,Q9BV73,Q15154,Q7Z4H7,Q96CS2,O15078,Q14008,P23258 13 +Interactions of vpr with host cellular proteins 0.2904784686285228 0.6626256862039245 0.5075703150988888 1.0 0.9208567619333018 35 O75475,P12270,Q9UKX7,P55735,P49790,Q7Z3B4,P35658,Q96EE3,Q8NFH5 9 +Type i hemidesmosome assembly 0.6538037486218367 0.6618013764188275 0.5080985239004192 1.0 0.9208567619333018 2 Q15149 1 +Assembly of collagen fibrils and other multimeric structures 0.6538037486218367 0.6618013764188275 0.5080985239004192 1.0 0.9208567619333018 2 Q15149 1 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.3323803868642425 0.6483196377476069 0.5167782352076085 1.0 0.9335135043686156 20 P19022,P14314,P11047,P07942 4 +Sumoylation of dna methylation proteins 0.6641852770885002 0.6345903509067828 0.5256956229253842 1.0 0.94598356666905 3 P26358,Q99496 2 +Establishment of sister chromatid cohesion 0.4125304813697896 0.6292594222507545 0.5291792320455202 1.0 0.9486177327635344 8 Q14683 1 +Negative regulators of ddx58 ifih1 signaling 0.4398614050651013 0.6270796478130096 0.5306070272617789 1.0 0.9491683261860964 7 Q13526 1 +Processing of intronless pre mrnas 0.3416480577319265 0.6245876138968124 0.5322417510186828 1.0 0.9504798823641624 16 Q05048,Q6UN15,Q9C0J8 3 +Gap junction trafficking and regulation 0.3760789348491669 0.6210433629346604 0.534571092505987 1.0 0.9534312270138426 12 Q9UM54,P09496,Q07157,Q9BVA1 4 +Rmts methylate histone arginines 0.3195169031017438 0.6168331388718872 0.5373447914280489 1.0 0.9561313193478436 22 P16104,Q96GM5,Q16576,Q86U86,Q92925,Q8TAQ2,Q969G3,Q92922,Q12824,P11802,O14497,P62805 12 +Antiviral mechanism by ifn stimulated genes 0.2661897791260887 0.6143611208874995 0.5389767214727796 1.0 0.9561313193478436 52 P12270,Q9UKX7,Q13526,P55735,O75369,P49790,P61088,P21333,P35658,Q96EE3,Q8NFH5 11 +Activation of the pre replicative complex 0.3090359908955924 0.6126016942462206 0.5401397377067902 1.0 0.9561313193478436 24 O00311,Q9NRF9,Q13416,P33991 4 +Rhov gtpase cycle 0.3339745383489692 0.6095011946082503 0.5421922811631845 1.0 0.9561313193478436 18 Q13177,Q13813,P46940,Q01082,O96013,Q96KM6 6 +Synthesis of ip3 and ip4 in the cytosol 0.6542829100545481 0.6005804409704545 0.5481194684506447 1.0 0.9642660127064208 3 Q13572 1 +Ovarian tumor domain proteases 0.4332439862817949 0.5962131349740198 0.5510328519534595 1.0 0.9650490329587949 7 Q7Z434 1 +Initiation of nuclear envelope ne reformation 0.3366013049537846 0.5918618101860753 0.5539431288354411 1.0 0.9683695639319312 16 P42167,Q8NC56,Q14739,Q9Y2U8,P02545,P20700,P50402 7 +Glyoxylate metabolism and glycine degradation 0.348434803990412 0.5829760954868597 0.5599093924834322 1.0 0.9772908525730108 14 P23378,P09622,P30038,Q9UBQ7,Q02218,P36957,P11177,P00505 8 +Cilium assembly 0.2482134723984483 0.5706908624785487 0.568209213851443 1.0 0.9798478870151134 74 Q13409,Q9UPN4,Q15051,Q9Y366,Q9BV73,Q96KP1,Q15019,Q8NCM8,Q14008,O15078 10 +Bile acid and bile salt metabolism 0.4273672442541839 0.5691671323669921 0.5692427234633213 1.0 0.9798478870151134 7 Q9H4L5,P22059,P51659 3 +Synthesis of bile acids and bile salts 0.4273672442541839 0.5691671323669921 0.5692427234633213 1.0 0.9798478870151134 7 Q9H4L5,P22059,P51659 3 +Signaling by activin 0.6267916207276647 0.5619672223105097 0.5741383516303586 1.0 0.9829416007863612 2 P27361 1 +Runx2 regulates osteoblast differentiation 0.6267916207276647 0.5619672223105097 0.5741383516303586 1.0 0.9829416007863612 2 P27361 1 +Signaling by nodal 0.6267916207276647 0.5619672223105097 0.5741383516303586 1.0 0.9829416007863612 2 P27361 1 +Rna polymerase i promoter escape 0.3308505064307396 0.5552091041902113 0.5787516424071382 1.0 0.9884376535171608 16 P16104,P84243,P17480,Q13185,O15160,P32780,P62805 7 +Ns1 mediated effects on host pathways 0.2796980801633784 0.5526688001203515 0.5804902213256429 1.0 0.989127492101678 34 P12270,Q9UKX7,P55735,P49790,P35658,Q96EE3,Q8NFH5 7 +Signaling by hippo 0.4237203168908091 0.5525675442566481 0.5805595713045335 1.0 0.989127492101678 7 Q4VCS5,Q07157,Q9UDY2 3 +B wich complex positively regulates rrna expression 0.3217726305653844 0.5494723387253178 0.5826813424648898 1.0 0.99034742042585 19 P16104,O15160,Q9NR30,O00159,Q9UIG0,P62805 6 +Notch hlh transcription pathway 0.4875838083549272 0.5367201798477848 0.5914609146266416 1.0 0.996313601235008 5 Q13573 1 +Trafficking of myristoylated proteins to the cilium 0.6196251378169699 0.5363913160184136 0.5916881318251008 1.0 0.996313601235008 2 A6NIH7 1 +Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.2590321643492603 0.5361592950183658 0.5918484629053951 1.0 0.996313601235008 52 Q04637,P20042,P61247,P62841,P62861,P62753,P23588,P62269,P62277,Q15056,P62273,P62081,P62857,O75821,P39019,P46783,P60866,P46782,P62263,P11940,O75822,P62847,Q13347 23 +Galactose catabolism 0.6176957001102443 0.5295771528480852 0.5964051385522917 1.0 1.0 2 Q96G03 1 +Myoclonic epilepsy of lafora 0.6165931642778435 0.5256973471872457 0.599098507281822 1.0 1.0 2 P13807 1 +Mrna decay by 5 to 3 exoribonuclease 0.363735573948216 0.5181254227287084 0.6043707636230284 1.0 1.0 11 Q6P2E9 1 +Runx2 regulates bone development 0.6269644334160429 0.5098925188192915 0.6101267634281264 1.0 1.0 3 P27361,Q96PK6 2 +Signal attenuation 0.6269644334160431 0.5098925188192912 0.6101267634281267 1.0 1.0 3 P27361,P62993 2 +Base excision repair ap site formation 0.4387447002072689 0.5040708908585255 0.6142115615782322 1.0 1.0 6 P16104,P62805 2 +A tetrasaccharide linker sequence is required for gag synthesis 0.6091510474090313 0.4997819610763049 0.6172286137096614 1.0 1.0 2 O94766 1 +Gap filling dna repair synthesis and ligation in gg ner 0.3104524214749134 0.4964026509288538 0.6196103551249093 1.0 1.0 20 Q9NRF9,P18887 2 +Homologous dna pairing and strand exchange 0.320779723201462 0.4928429277953862 0.6221235760485424 1.0 1.0 16 Q92878 1 +Hdr through single strand annealing ssa 0.320779723201462 0.4928429277953862 0.6221235760485424 1.0 1.0 16 Q92878 1 +Condensation of prometaphase chromosomes 0.373090750639297 0.4849179777680225 0.6277345292791106 1.0 1.0 9 O95347,P67870 2 +Advanced glycosylation endproduct receptor signaling 0.3730216733354899 0.4845845385593417 0.6279710834699888 1.0 1.0 9 P14314 1 +Nuclear envelope ne reassembly 0.2533898885385695 0.4769268360932912 0.6334142215793288 1.0 1.0 52 P42167,Q9UN37,Q9H444,Q8NC56,Q9UQN3,Q9BVA1,P18754,Q9Y3E7,Q8WYP5,Q9Y2U8,P55735,P02545,P53990,Q7Z3B4,P20700,P50402,Q96EE3,Q8NFH5 18 +Ptk6 regulates rho gtpases ras gtpase and map kinases 0.5054687183347386 0.4594443204976254 0.6459151274174642 1.0 1.0 4 Q96JJ3 1 +Lipophagy 0.5052299576680928 0.4586186375498874 0.6465080504130494 1.0 1.0 4 O60664 1 +G2 m dna damage checkpoint 0.2682267530799452 0.4540454972834082 0.6497960803974387 1.0 1.0 34 P16104,O60934,Q14676,P61088,P54132,Q92878 6 +Signaling by erbb2 0.3448493178232922 0.450799809288524 0.6521338387804456 1.0 1.0 12 Q16543,P62993,P40818,Q05655,O60610 5 +Gene silencing by rna 0.250079903662515 0.4474866634834657 0.6545237150419658 1.0 1.0 50 P16104,Q8NFH5,P12270,Q9UKX7,P24928,P55735,P49790,P35658,Q96EE3,P62805 10 +Signaling by notch1 pest domain mutants in cancer 0.373550977463201 0.4424277685816905 0.658179688488808 1.0 1.0 8 Q13573 1 +Rho gtpase effectors 0.2728175567617728 0.4383409976312467 0.6611391106798132 1.0 1.0 129 Q13464,Q8NBT2,P84243,Q8IZP0,Q12834,Q8WYP5,Q99661,Q16513,Q9BVA1,Q71F23,Q7Z406,P46940,P35221,P62993,O00139,P33176,P62805,Q13177,Q86UP2,Q13526,O14974,P55735,Q14008,Q9NQS7,Q14247,P59998,Q13409,P16104,Q9Y6D9,P84095,Q7Z460,Q86VI3,Q9H3R5,Q9Y6W5,Q53HL2,P35580,Q9Y6G9,P35579,O60610,P49792,O75116,O43237,Q9UQB8,P21333,Q05655,Q96EE3 46 +Trna processing in the nucleus 0.2555076220938672 0.4320903797543697 0.6656757264050104 1.0 1.0 45 P12270,Q9UKX7,Q9BVC5,P55735,Q92499,P49790,P33240,Q7Z3B4,P35658,Q96EE3,Q8NFH5 11 +Rac3 gtpase cycle 0.2583716018131879 0.4113969990353317 0.6807814540480988 1.0 1.0 38 Q13177,Q15758,P42167,Q8IZP0,P11274,P49257,O96013,Q9H0H5,Q9UQB8,Q9Y2U8,Q9Y6W5,Q12979,Q07960,Q13112,P50402 15 +Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.340942546400382 0.4030885289113576 0.6868830990362289 1.0 1.0 11 Q96ST3,P16104,P84243,Q15291,P62805 5 +Processing of capped intronless pre mrna 0.3013042059531768 0.4021853827793855 0.687547598937464 1.0 1.0 18 Q05048,Q9C0J8 2 +Smad2 smad3 smad4 heterotrimer regulates transcription 0.4884498729256394 0.4019978229275415 0.6876856284914976 1.0 1.0 4 P27361,P28482 2 +Hiv transcription initiation 0.3022573411118961 0.3949453578235693 0.6928832146405144 1.0 1.0 17 Q00403,P18074,P29083,Q92804,P13984,P24928,O15514,P35269,P32780 9 +Nuclear signaling by erbb4 0.4855932898966619 0.3926491007621086 0.6945786690033542 1.0 1.0 4 P78536 1 +Amino acids regulate mtorc1 0.3236414378878829 0.3889855481579078 0.6972868370709884 1.0 1.0 13 P42345,P55735,P36543,Q96EE3 4 +Unwinding of dna 0.3426902621896111 0.3878633647207707 0.6981171506102046 1.0 1.0 10 P33991,P25205 2 +Cell death signalling via nrage nrif and nade 0.3423470533216651 0.3862789157266107 0.6992901138537593 1.0 1.0 10 Q12979,Q92974,Q12802,Q92888 4 +Cdc42 gtpase cycle 0.255282203608669 0.385881864429087 0.6995841624635837 1.0 1.0 38 Q13177,P11274,A1A4S6,O96013,Q86UP2,Q9H0H5,Q86VI3,Q96N67,P46940,Q9UQB8,Q07960,Q9Y5S2 12 +Signal transduction by l1 0.3371096988118361 0.384806372713241 0.700380877291219 1.0 1.0 11 P63000,P19784,Q16512,P28482,P05556,P67870,Q02750,P06756,P27361,P68400 10 +Citric acid cycle tca cycle 0.2954412026579247 0.3831981648951561 0.7015728385734517 1.0 1.0 19 O43837,P31040,P09622,P53597,Q96I99,P36957,P48735,Q99798 8 +Resolution of sister chromatid cohesion 0.2349696932213284 0.3794660191219344 0.7043418334994374 1.0 1.0 72 Q13409,Q9Y6D9,Q9UQE7,Q12834,Q8WYP5,Q9H3R5,P55735,O43237,Q14008,Q9NQS7,Q8NBT2,Q14683 12 +Apobec3g mediated resistance to hiv 1 infection 0.5842346735072534 0.3792702273040427 0.7044872061574396 1.0 1.0 3 O75475 1 +Parasite infection 0.2802105455613789 0.3722017919720295 0.7097426119915522 1.0 1.0 23 P59998,Q8IZP0,P46108,Q96JJ3,Q9UQB8,Q9Y6W5,O00159,P35579 8 +Processive synthesis on the c strand of the telomere 0.3281914945933567 0.3680143620921809 0.7128625251711584 1.0 1.0 12 P39748,P54132 2 +Collagen formation 0.3177937289705257 0.3599124174914082 0.7189126306540956 1.0 1.0 13 Q03001,P50454,Q32P28,O60568,P13674,Q15149,P07237,Q02809 8 +Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.3446185800840473 0.3547948856628945 0.7227432601059103 1.0 1.0 9 P06748,O75175,Q9UKZ1 3 +Folding of actin by cct tric 0.3522915516289324 0.3506509326588118 0.7258502409336216 1.0 1.0 8 P50991,P40227,P78371,P48643,P49368,P17987,P50990 7 +Pre notch expression and processing 0.3239977222035027 0.3482330707468111 0.7276651533651206 1.0 1.0 12 P16104,Q13573,P62805 3 +Golgi cisternae pericentriolar stack reorganization 0.3334561826446524 0.3461536510993738 0.7292272449973538 1.0 1.0 10 Q9H8Y8 1 +L1cam interactions 0.2444999123887684 0.3443583983842496 0.7305767710627773 1.0 1.0 46 Q9BVA1,P17301,P26038,P07942,Q13740,P35241,O95239,P15311,P09496,P50570,Q13813,P27361,P11047,Q16555,Q01082,Q15334,Q9UQ16,P67870,P11142 19 +Global genome nucleotide excision repair gg ner 0.2442366660524896 0.3421155930025263 0.7322639032040945 1.0 1.0 46 P09874,Q9UBW8,P49916,P61956,Q9H981,P18887,P61088,Q9NRF9,P25490 9 +Gaba synthesis release reuptake and degradation 0.5676926125406581 0.3331023646705646 0.739057014471747 1.0 1.0 3 P11142 1 +Rna polymerase iii transcription termination 0.3710455361631704 0.3325742552761726 0.7394556794518503 1.0 1.0 7 P05455,O14802 2 +Fgfr2 alternative splicing 0.2922917706571555 0.3317675261697214 0.7400648070734832 1.0 1.0 16 P26599,P52272,P13984,P24928,Q01085 5 +Unblocking of nmda receptors glutamate binding and activation 0.4290818951742569 0.3262471558994781 0.7442373661533037 1.0 1.0 5 Q14168,Q15334,P07196 3 +Long term potentiation 0.4290818951742569 0.3262471558994781 0.7442373661533037 1.0 1.0 5 Q14168,Q15334,P07196 3 +Ras activation upon ca2 influx through nmda receptor 0.4290818951742569 0.3262471558994781 0.7442373661533037 1.0 1.0 5 Q14168,Q15334,P07196 3 +Interferon gamma signaling 0.3013914549890704 0.3242940178154626 0.745715448270748 1.0 1.0 14 O15344,P19474,P30511,Q05655 4 +Fcgamma receptor fcgr dependent phagocytosis 0.2527414617316008 0.3188345947458291 0.7498519434391968 1.0 1.0 31 P59998,Q8IZP0,P46108,P35579,Q96JJ3,Q9UQB8,Q05655,Q9Y6W5,P08238,P62993,O00159 11 +Early phase of hiv life cycle 0.3441432588428798 0.3178244823618822 0.7506180786246401 1.0 1.0 8 O75475,P39748 2 +G beta gamma signalling through cdc42 0.5601929088865286 0.3130806260637512 0.7542194078837761 1.0 1.0 3 Q9UBI6 1 +Cytosolic sensors of pathogen associated dna 0.2800085333279857 0.3106536092798243 0.756063967794883 1.0 1.0 20 Q13049 1 +Repression of wnt target genes 0.4558742415885195 0.3009749664398313 0.7634335838475657 1.0 1.0 4 Q04726,Q13363,P56545 3 +Cd28 co stimulation 0.3385205688810848 0.2960064517517536 0.7672251542922732 1.0 1.0 8 Q13177,P42345 2 +Prolonged erk activation events 0.3605585115960845 0.2941872715604761 0.7686148063503069 1.0 1.0 7 P27361,P46108,Q9ULH0 3 +Negative feedback regulation of mapk pathway 0.5515662164315924 0.2907873384799653 0.7712139695432079 1.0 1.0 3 P27361 1 +Anti inflammatory response favouring leishmania parasite infection 0.3022486837918057 0.2873706830070282 0.7738285064874777 1.0 1.0 13 P35579 1 +Assembly of the orc complex at the origin of replication 0.319051324760591 0.2851727162016276 0.7755118221772557 1.0 1.0 10 P16104,Q13416 2 +Uptake and function of diphtheria toxin 0.4500364020023646 0.2842584106691489 0.7762123555006548 1.0 1.0 4 P08238,Q16881 2 +Oncogene induced senescence 0.3561592412171229 0.2787176234048424 0.7804615367356953 1.0 1.0 7 P27361,P42771,P28482,P11802 4 +Uptake and function of anthrax toxins 0.5350055126791495 0.2728041112375287 0.7850037990877787 1.0 1.0 2 Q8WUM4 1 +Rhof gtpase cycle 0.2786920219220302 0.2705756686039575 0.7867174116104052 1.0 1.0 17 P42167,P80723,Q5JTV8,Q07960,P20700,O60610,Q02952 7 +Regulation of signaling by cbl 0.5401361852022379 0.2625101607572751 0.7929281528155647 1.0 1.0 3 P46108 1 +Signaling by erbb4 0.3507909625874234 0.2603696506663088 0.7945786510758248 1.0 1.0 7 P78536 1 +Role of second messengers in netrin 1 signaling 0.5283902976846618 0.25577602439825 0.7981237879889922 1.0 1.0 2 Q00169 1 +Autophagy 0.2290790189551108 0.246983050596073 0.80492134146481 1.0 1.0 56 Q13409,Q9H444,Q96HS1,Q9UQN3,Q9Y3E7,P42345,Q9NT62,Q9Y6G9,O43237,P67870,P61088,P08238,O60664,P55072,P11142 15 +Telomere maintenance 0.2340046339569116 0.2469755256159241 0.8049271651743435 1.0 1.0 44 Q9UER7,Q8WVB6,P16104,O60832,Q9NPE3,P24928,P54132,P39748,P62805 9 +Chaperone mediated autophagy 0.3458350920014159 0.243962119089309 0.8072601581814856 1.0 1.0 7 P08238,O60664,P11142 3 +Neurotransmitter release cycle 0.323707638070167 0.2420078830961468 0.8087740549422429 1.0 1.0 8 O75915,Q13136,P11142 3 +Tp53 regulates transcription of dna repair genes 0.2412138339691942 0.2404584844570187 0.8099748437847354 1.0 1.0 30 P23193,Q9Y5B9,P13984,P24928,Q14241,P18615,Q14676,O00267,P35269,P32780 10 +Ephb mediated forward signaling 0.3033362541713456 0.2397426318114975 0.8105297831364924 1.0 1.0 11 P59998,Q13464 2 +Nucleotide excision repair 0.2277184654073227 0.2394240317862275 0.8107767971410718 1.0 1.0 61 P24928,P18887,Q99627,Q9H9Q2,P23193,P61956,Q9H981,Q13620,P61088,P35251,P25490,P05114,Q9ULR0,Q9UBW8,Q9UNS2,P32780,P54727,P09874,P49916,Q9NRF9 20 +Rna polymerase ii transcribes snrna genes 0.2411620835218834 0.2388271144899331 0.8112396442055041 1.0 1.0 27 Q9NQG5,Q96P16,P29083,P13984,P24928,Q8N201,Q9H814,P35269,Q9H0H0 9 +Rhod gtpase cycle 0.2401343629457867 0.2356151830014172 0.8137312907903678 1.0 1.0 31 P42167,P49257,Q9H0H5,Q14739,Q9Y2U8,Q5JTV8,Q9BX68,Q07960,P20700,P50402,O60610,Q02952 12 +Sema3a pak dependent axon repulsion 0.3420088993304364 0.2316520080177973 0.8168083094720635 1.0 1.0 7 Q13177,P08238 2 +Glycolysis 0.2246312953944076 0.2236811487531288 0.823005415424507 1.0 1.0 50 P12270,Q9UKX7,P18669,P09104,P55735,P49790,P35658,Q96EE3,Q8NFH5 9 +Interferon signaling 0.2234128507913381 0.2235926328311351 0.8230742966989937 1.0 1.0 67 P12270,Q9UKX7,Q13526,P55735,P30511,P49790,O75369,P61088,P21333,P35658,Q96EE3,Q8NFH5 12 +Ion transport by p type atpases 0.298861867190028 0.2229283109244653 0.8235913018521777 1.0 1.0 11 Q5EBL8,P05026 2 +Selective autophagy 0.235477954255139 0.2206441000800848 0.8253695602930633 1.0 1.0 35 Q13409,Q96HS1,O43237,P67870,P61088,Q9Y6G9,O60664,P55072 8 +Glutamate neurotransmitter release cycle 0.4230866015173439 0.2131762153325418 0.831189519295296 1.0 1.0 4 O75915 1 +Activation of rac1 0.3560997210360775 0.2098608318993342 0.8337762930637869 1.0 1.0 6 O96013 1 +Rrna processing in the mitochondrion 0.3328036174457521 0.2033475750023243 0.8388633727443087 1.0 1.0 7 Q8WVM0 1 +E3 ubiquitin ligases ubiquitinate target proteins 0.259730338317709 0.1867883755114211 0.8518265615079894 1.0 1.0 17 Q14527,Q8N7H5,Q6P1J9,O75150,P55072,P61088,Q92541 7 +Syndecan interactions 0.3468543046357675 0.1842745085056331 0.8537981107332426 1.0 1.0 6 P17301,Q9Y296,P05556,P06756,P12814 5 +Fceri mediated ca 2 mobilization 0.4106453392167762 0.1839342717602323 0.8540650184890297 1.0 1.0 4 P19174,O43865,P62993 3 +Signaling by fgfr 0.2493039630483654 0.183624915639857 0.8543077156173355 1.0 1.0 22 P09651,P26599,P52272,P13984,P24928,O15514,P62993,P35269,Q01085 9 +Signaling by fgfr2 0.2493039630483654 0.183624915639857 0.8543077156173355 1.0 1.0 22 P09651,P26599,P52272,P13984,P24928,O15514,P62993,P35269,Q01085 9 +Rhoj gtpase cycle 0.2289555055026932 0.1707719305167321 0.8644031010268698 1.0 1.0 27 Q15758,Q86VI3,O75323,O96013,Q07960,Q13112,Q9Y5S2 7 +Dap12 interactions 0.369330685675063 0.1605959830039391 0.8724116189297035 1.0 1.0 5 P62993 1 +Mapk3 erk1 activation 0.3993381136238346 0.1594090570598549 0.8733466036530309 1.0 1.0 4 P27361,P06493,Q02750 3 +Extracellular matrix organization 0.2252759230961288 0.1585703025005199 0.8740074278794459 1.0 1.0 34 P55081,P11047,P07942 3 +Polb dependent long patch base excision repair 0.3344350381799603 0.1526269542669912 0.8786924676044863 1.0 1.0 6 P39748 1 +Cohesin loading onto chromatin 0.279908593928471 0.1485186453695879 0.881933472256001 1.0 1.0 10 Q14683 1 +Mhc class ii antigen presentation 0.2156807386706901 0.1465506843141417 0.8834866814843549 1.0 1.0 60 Q13409,Q13561,Q14203,Q99661,Q9BVA1,Q9H0H5,Q02241,Q9Y496,P09496,O43237,P55735,Q14807,P47755,Q9Y6G9,O95487,O94979,P33176 17 +Diseases of programmed cell death 0.2238453754270756 0.1444802618006571 0.8851212417137475 1.0 1.0 29 P49642,P16104,Q15910,Q16576,P84243,P26358,P02545,Q08379,P20700,P62805 10 +Regulation of mecp2 expression and activity 0.2773762716570457 0.1412738580069773 0.8876536007564064 1.0 1.0 10 P51608 1 +Metalloprotease dubs 0.3294701986755005 0.1408668007804568 0.8879751697124503 1.0 1.0 6 Q92783,O00487,O95630,P38398,Q15018 5 +Inactivation of cdc42 and rac1 0.4797353184449913 0.138886844785738 0.889539566552527 1.0 1.0 3 P60953,O94813 2 +Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.4721609702315216 0.1358865265498939 0.8919109869283262 1.0 1.0 2 O00767 1 +Tp53 regulates transcription of death receptors and ligands 0.4721609702315176 0.1358865265498866 0.8919109869283319 1.0 1.0 2 P04637 1 +Regulation of tp53 expression and degradation 0.2599411771492816 0.1306312216146781 0.896067043077565 1.0 1.0 13 Q9UER7 1 +Diseases of signal transduction by growth factor receptors and second messengers 0.2597227063742569 0.1286686678975182 0.8976198286749608 1.0 1.0 153 Q9UBW7,Q9NWH9,Q13573,O00233,P13984,P51608,Q9P2E9,P33176,P18206,P12270,Q92614,Q6WCQ1,Q96PU8,Q8IWJ2,Q9Y490,P06748,P62753,Q14203,P84095,O43815,O00291,P02545,Q01082,P55036,P35579,P42345,P17980,Q9HC35,P55072,P78536,Q6UN15 31 +Chl1 interactions 0.3798276042770354 0.1217830040215196 0.9030708745769562 1.0 1.0 4 P11142 1 +Formation of rna pol ii elongation complex 0.2182214185735349 0.1217269364420583 0.90311527967351 1.0 1.0 33 P35269,P23193,P18074,Q8N7H5,Q9Y5B9,P13984,P24928,Q7KZ85,Q14241,Q6P1J9,P18615,O00267,Q92541,P32780 14 +Regulation of pyruvate dehydrogenase pdh complex 0.2696132596684996 0.1203219729161485 0.9042280986887684 1.0 1.0 10 P08559,P10515,Q15118,P09622,Q8NCN5,O00330,Q9P0J1,P11177,O43708 9 +Mitotic telophase cytokinesis 0.2540429777548526 0.1139622633465708 0.9092677079848726 1.0 1.0 13 Q9UQE7,Q14683 2 +Mtor signalling 0.2388702927134583 0.1122474603085157 0.9106271990310072 1.0 1.0 16 P23588,P62753 2 +Arms mediated activation 0.4604424972754042 0.1089666771053762 0.9132289207302058 1.0 1.0 3 Q9ULH0 1 +Signaling by scf kit 0.3440000000000035 0.1088698856834909 0.913305692379672 1.0 1.0 5 P63000,P62993,Q06124,P42224 4 +Signaling by vegf 0.2155943436172793 0.1087055094863346 0.9134360718173652 1.0 1.0 32 Q13177,Q13464,Q8IZP0,P46108,P42345,Q96JJ3,Q9UQB8,Q9Y6W5,P35221,O75116,Q05655 11 +Protein ubiquitination 0.2224048092400146 0.1081973824023123 0.9138391213081604 1.0 1.0 25 Q14527,Q8N7H5,Q5VTR2,Q6P1J9,P22314,O75150,P55072,P61088,Q92541 9 +Translation of sars cov 1 structural proteins 0.2746266036835074 0.1033275332178294 0.917703024220626 1.0 1.0 8 P26572,P14314,Q14697 3 +Insulin receptor signalling cascade 0.3115342163355417 0.1026834913847297 0.9182141763447114 1.0 1.0 6 Q06124,P28482,Q99570,P27361,P62993 5 +Collagen biosynthesis and modifying enzymes 0.2594047992491989 0.1022915321327861 0.9185252764309944 1.0 1.0 11 O15460,P50454,Q32P28,P13674,O60568,P07237,Q02809 7 +Generation of second messenger molecules 0.3399668342841719 0.1016984001889032 0.9189960720278494 1.0 1.0 5 Q13177 1 +Platelet adhesion to exposed collagen 0.4487320837927073 0.0994005613659162 0.9208202370670008 1.0 1.0 2 P17301 1 +Processive synthesis on the lagging strand 0.2466132153718535 0.0948121566456353 0.9244640307666488 1.0 1.0 13 P49642,P15927,P35244,P28340,Q9Y2S7,P09884,P18858,Q14181,P49005,P27694,P12004,P39748 12 +Rho gtpases activate nadph oxidases 0.2854469597980966 0.0887816976168268 0.9292554034302128 1.0 1.0 7 P27361,Q13526,Q05655 3 +Rhog gtpase cycle 0.2073537418262734 0.0869102943609617 0.9307428167684216 1.0 1.0 40 Q13177,P42167,P84095,P49257,Q86UP2,Q96JJ3,Q9Y2U8,O75489,P61604,O96013,Q07960,Q13112,P50402 13 +Programmed cell death 0.2183311876159514 0.0833905782178248 0.9335409799118972 1.0 1.0 106 Q13464,Q9UQN3,A1A4S6,Q9Y3E7,O00233,Q07157,P16402,Q13813,P16403,P10412,Q9H444,P07305,Q9UKV3,P02545,P55036,Q15149,P26583,Q9UDY2,Q16625,P17980 20 +Dna damage recognition in gg ner 0.2261618126794613 0.0821909852421591 0.9344948419266196 1.0 1.0 19 P54727,P09874,Q9UBW8,Q99627,Q9H981,Q13620,Q9H9Q2,P25490 8 +Nervous system development 0.2847975611779484 0.0799485745404286 0.9362781565451656 1.0 1.0 219 Q13464,Q9NWH9,O00233,P62913,Q7Z406,P83731,P46939,P26373,P07942,P61247,Q13177,P50914,P62917,P84098,P62841,P15311,P09496,P62861,Q02878,Q13813,P47914,P46778,Q9Y490,P59998,P62753,P61254,P62424,Q9HAU5,P62750,Q9BPU6,P11047,P62273,P62081,P62899,P62857,Q01082,P55036,P35580,P35579,P46779,P61353,P39019,P46777,P46782,P62263,Q9NR12,P11940,P83881,P05387,O96013,Q15287,P17980,Q9BZI7,P40429,P67870,O75116,P11142 57 +Hiv elongation arrest and recovery 0.2225129079700511 0.0784849575696222 0.937442295431084 1.0 1.0 21 Q9Y5B9,P13984,P24928,Q14241,P18615,O00267,P35269 7 +Beta oxidation of pristanoyl coa 0.3246896551724176 0.0771505602340734 0.9385037715747022 1.0 1.0 5 O14734,Q9UKG9,P51659,O15254 4 +Telomere c strand synthesis initiation 0.3241141702405922 0.0763056744277531 0.9391759114681076 1.0 1.0 5 Q9NYB0 1 +Esr mediated signaling 0.2027238124176242 0.0758910031256979 0.939505814683518 1.0 1.0 47 P16104,P84243,Q08752,Q9UQE7,O43815,O14646,P13984,P24928,P25490,O15514,Q13451,P62805,P08238,Q15648,P27361,P35269,P07900,Q14683 18 +Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.4339674662255259 0.0753531924172202 0.939933700313331 1.0 1.0 3 Q13547,P06493 2 +Receptor mediated mitophagy 0.2954829112076351 0.0742033410964738 0.9408485873721528 1.0 1.0 6 Q96HS1 1 +Negative regulation of nmda receptor mediated neuronal transmission 0.2770690568316794 0.0740195644541152 0.940994817779788 1.0 1.0 7 Q14168,P49593 2 +Activation of atr in response to replication stress 0.2217268696744616 0.0730443869904831 0.9417707961145216 1.0 1.0 20 O00311,Q13416,P33991 3 +Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.4304546736384442 0.0715167768362869 0.9429864727615056 1.0 1.0 3 P12814 1 +Regulation of insulin secretion 0.2325091365532377 0.0640106267231763 0.948961765260928 1.0 1.0 13 P29966 1 +Metabolism of ingested semet sec mesec into h2se 0.4226559283520216 0.0634999273108205 0.949368417126331 1.0 1.0 3 Q96I15 1 +Mrna editing 0.4173098125688975 0.0623241043428523 0.9503047332971664 1.0 1.0 2 P55265 1 +Developmental biology 0.2920549552895649 0.0618954622759136 0.950646081150472 1.0 1.0 270 Q9NWH9,O00233,O60271,Q7Z406,P83731,P07942,P62917,P84098,Q14966,P62841,P47914,P25490,P62424,P62750,Q9BPU6,P62081,P62899,Q01082,P55036,Q9NR12,P17980,P40429,Q13464,Q13573,P24928,P62805,Q16576,Q9Y2W1,P19022,P46778,Q9Y490,Q15910,P61254,P11047,P35579,P46779,P61353,P46782,P62263,P11940,P83881,Q15287,Q15291,P67870,O75116,P11142,P62913,Q15648,P11802,P46939,P26373,P61247,Q13177,P50914,Q13740,Q71SY5,P09496,P62861,Q9NVC6,Q13813,P46776,P16104,Q8N8S7,P62857,P35580,P08238,P39019,P36578,P62847,Q9NPJ6,Q9BVA1,P35221,P15311,Q02878,P62753,P59998,Q9HAU5,P62273,P46777,P05387,Q9BZI7,O96013 82 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3114482758620727 0.0591367440104568 0.952843192352088 1.0 1.0 5 Q99570,P62993,O14654,Q06124 4 +Suppression of apoptosis 0.2844555103682878 0.0576679007875061 0.954013162589032 1.0 1.0 6 P23246 1 +Signaling by erythropoietin 0.4099807003032758 0.0518915399785677 0.9586151153144422 1.0 1.0 3 P19174,P62993 2 +Signaling by ntrk3 trkc 0.4091535704438877 0.0511930888960469 0.9591716588875052 1.0 1.0 3 P19174,P62993 2 +Costimulation by the cd28 family 0.2113416320885219 0.0491201144296335 0.9608235737579652 1.0 1.0 15 Q13177,P63000,P31751,P60953,Q06124,P42345,Q16512,Q14738,P30154,P41240,Q13362,Q16537,P62993,P30153 14 +Pcna dependent long patch base excision repair 0.2101540224813417 0.046524239400779 0.9628924147530552 1.0 1.0 20 Q9NRF9 1 +Mapk1 erk2 activation 0.3991179713340587 0.0464918485669931 0.9629182309639316 1.0 1.0 2 P28482 1 +Pi 3k cascade fgfr1 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Signaling by flt3 itd and tkd mutants 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Pi 3k cascade fgfr2 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Frs mediated fgfr3 signaling 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Pi 3k cascade fgfr4 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Pi 3k cascade fgfr3 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Stat5 activation 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Stat5 activation downstream of flt3 itd mutants 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Frs mediated fgfr1 signaling 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Frs mediated fgfr2 signaling 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Frs mediated fgfr4 signaling 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Activated ntrk2 signals through frs2 and frs3 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Tie2 signaling 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Protein methylation 0.257586764212447 0.045772726796146 0.9634913968828732 1.0 1.0 7 P38117,P11142,P55072 3 +Pecam1 interactions 0.3992280121312327 0.0433519063511256 0.965421014800562 1.0 1.0 3 P19174,P06756 2 +Downstream signaling of activated fgfr3 0.3992280121312325 0.0433519063511256 0.965421014800562 1.0 1.0 3 P19174,P62993 2 +Downstream signaling of activated fgfr4 0.3992280121312325 0.0433519063511256 0.965421014800562 1.0 1.0 3 P19174,P62993 2 +Downstream signaling of activated fgfr1 0.3992280121312325 0.0433519063511256 0.965421014800562 1.0 1.0 3 P19174,P62993 2 +Downstream signaling of activated fgfr2 0.3992280121312325 0.0433519063511256 0.965421014800562 1.0 1.0 3 P19174,P62993 2 +Gab1 signalosome 0.3992280121312326 0.0433519063511253 0.9654210148005622 1.0 1.0 3 P62993,P41240 2 +Other interleukin signaling 0.3988288159439153 0.0430569342221035 0.9656561489516016 1.0 1.0 3 Q12846 1 +Rho gtpase cycle 0.25804363312006 0.0396352459374229 0.9683839273121198 1.0 1.0 172 Q13464,Q8IZP0,A1A4S6,Q16513,P31948,Q9H0H5,Q9NZM3,P38159,Q96N67,P46940,P61604,Q92974,Q96KM6,P50402,Q15758,Q7Z6E9,Q13177,Q12802,Q92888,Q86UP2,Q16543,P80723,Q5JTV8,Q13813,Q9BX68,Q9Y5S2,P11274,P84095,P49257,Q9UM54,Q9UNZ2,Q86VI3,Q9Y6W5,O14964,Q9NYL9,Q01082,P08238,Q07960,Q12979,O60610,Q9UDY2,O96013,Q96JJ3,O75116,Q9H2G2,P55072,Q9UQB8,O75323,Q13112,Q02952 50 +Atf6 atf6 alpha activates chaperones 0.3894707828004284 0.0395845143735157 0.9684243735023784 1.0 1.0 2 P14625 1 +Atf6 atf6 alpha activates chaperone genes 0.3894707828004284 0.0395845143735157 0.9684243735023784 1.0 1.0 2 P14625 1 +Synthesis of pips at the late endosome membrane 0.3869900771774952 0.0379627699236278 0.9697173659141572 1.0 1.0 2 O00443 1 +Tryptophan catabolism 0.390681003584224 0.037367268565718 0.9701921703355654 1.0 1.0 3 Q6YP21,Q01650 2 +Retrograde neurotrophin signalling 0.2297722730343618 0.0363753328476048 0.970983082695354 1.0 1.0 9 P09496,P50570 2 +Irs mediated signalling 0.3113623827909612 0.0353920202878728 0.9717671476151182 1.0 1.0 4 Q99570,P62993,Q06124 3 +Response of eif2ak1 hri to heme deficiency 0.3110865968008899 0.0351745364310552 0.9719405666472324 1.0 1.0 4 P08243,P20042,P05198 3 +Bbsome mediated cargo targeting to cilium 0.2284874793264574 0.0348547685588248 0.9721955481395655 1.0 1.0 9 P50991,Q9NQ48,P78371 3 +Perk regulates gene expression 0.2028223574986154 0.0341993763524283 0.9727181638501252 1.0 1.0 16 Q92945,Q13868,Q9Y2L1,P41091,P08243,Q5RKV6,Q06265,O95453,P20042,Q9NQT4,Q15024,P05198,Q9NQT5,Q9NPD3,Q96B26 15 +Rho gtpases activate formins 0.1930603017831908 0.0328388674149667 0.9738030832007616 1.0 1.0 71 Q13409,Q9Y6D9,Q12834,Q8WYP5,Q96EE3,Q9H3R5,P55735,O43237,Q9Y6G9,Q14008,Q9NQS7,Q8NBT2 12 +Telomere c strand lagging strand synthesis 0.1994606610349796 0.0306961480610839 0.9755118631184584 1.0 1.0 23 Q8WVB6,P54132,Q9NYB0,P35251,P39748 5 +Nrcam interactions 0.3737596471885218 0.0303050288597567 0.975823785966182 1.0 1.0 2 Q15334 1 +Ionotropic activity of kainate receptors 0.3737596471885218 0.0303050288597567 0.975823785966182 1.0 1.0 2 Q15334 1 +Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.1989690689429417 0.0297523186943773 0.976264586083904 1.0 1.0 23 Q9NRF9,P39748 2 +Mitotic spindle checkpoint 0.1935426066736452 0.0288338646671462 0.9769970920026236 1.0 1.0 67 Q13409,Q9NQS7,Q12834 3 +Activation of kainate receptors upon glutamate binding 0.3738626964433361 0.0274981835725409 0.9780623886000231 1.0 1.0 3 Q9UBI6,Q15334 2 +Synthesis of ip2 ip and ins in the cytosol 0.3738256451328699 0.0274790496815492 0.978077649469404 1.0 1.0 3 Q96PE3 1 +Trna processing 0.1924102421738865 0.0249575719644414 0.9800888057246712 1.0 1.0 68 Q8NFH5,P12270,Q9UKX7,Q9BVC5,P55735,Q92499,P49790,P33240,Q9H3H1,P35658,Q96EE3,Q96FX7 12 +Zinc influx into cells by the slc39 gene family 0.3583241455347217 0.0232791111028536 0.9814276341238092 1.0 1.0 2 Q9ULF5 1 +Attachment of gpi anchor to upar 0.2923331494760151 0.0224308715074731 0.9821042546408908 1.0 1.0 4 Q92643,O43292,Q969N2 3 +Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 0.2892995035852295 0.0207241554316228 0.9834656999083622 1.0 1.0 4 P55084,P42126,P40939 3 +Atf4 activates genes in response to endoplasmic reticulum stress 0.2026541332596054 0.0206621301778806 0.9835151783060836 1.0 1.0 13 Q13868,Q9Y2L1,P08243,Q5RKV6,Q06265,O95453,Q9NQT4,Q15024,Q92945,Q9NQT5,Q9NPD3,Q96B26 12 +Apoptosis 0.195199954984793 0.0193803953641835 0.9845376497051396 1.0 1.0 92 P16403,Q13464,P10412,Q07157,P26583,Q9UDY2,P16402,P07305,Q9UKV3,Q16625,O00233,P17980,P02545,Q13813,P55036,Q15149 16 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.3545629997242852 0.0189229155038019 0.9849025988841892 1.0 1.0 3 P11802,Q00534 2 +Interleukin 15 signaling 0.3437155457552258 0.0182415408011744 0.9854461633747298 1.0 1.0 2 P62993 1 +Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.2112676056338064 0.0180147765558929 0.985627065337234 1.0 1.0 9 P61086,P68036,P45974,Q93009,Q16763,Q93008,P22314,P60604 8 +Interconversion of nucleotide di and triphosphates 0.1899750761561826 0.0155998511806636 0.9875536244095358 1.0 1.0 19 P00390,P54819,P35754,Q7LG56,P27144,P00568,P17812,P22392,Q9NRF8,Q16881,P30085,Q9H773,Q9UIJ7,P23921,P04818,P31350,P23919,P33316 18 +Pentose phosphate pathway 0.2252484043070061 0.0155001707607476 0.98763314826244 1.0 1.0 7 P29401,Q96G03,O95336 3 +Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.3438103115522424 0.0152367961774111 0.9878432659602404 1.0 1.0 3 P62993,P42224 2 +Interleukin 2 family signaling 0.3438103115522424 0.0152367961774111 0.9878432659602404 1.0 1.0 3 P62993,P42224 2 +Signaling by kit in disease 0.3438103115522424 0.0152367961774111 0.9878432659602404 1.0 1.0 3 P62993,P42224 2 +Creatine metabolism 0.3380204025365264 0.0135340193250607 0.9892017445880958 1.0 1.0 3 P12532,P12277 2 +Vitamin b2 riboflavin metabolism 0.3213891951488329 0.0129536739134088 0.9896647526180258 1.0 1.0 2 Q969G6 1 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.1866952910579285 0.0127865663530509 0.9897980741181304 1.0 1.0 18 P50991,Q9BVA1,Q9UHV9,P78371,O15212 5 +Dissolution of fibrin clot 0.3333333333333279 0.0122878535555377 0.9901959580841632 1.0 1.0 3 P60903,P07355 2 +Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.3245106148331911 0.0102366984152781 0.9918324390275484 1.0 1.0 3 O14734,P51659 2 +Ret signaling 0.2511487703620524 0.0100918445676977 0.9919480097059076 1.0 1.0 5 Q9NR12 1 +Synthesis of pips at the early endosome membrane 0.2619376157369742 0.0090888546425185 0.9927482430468084 1.0 1.0 4 Q96PE3 1 +Striated muscle contraction 0.2288355047913827 0.0069224273686433 0.9944767461917032 1.0 1.0 6 Q9NYL9 1 +Signaling by ptk6 0.1892139779979602 0.0056697277777893 0.9954762359788384 1.0 1.0 12 P11802,Q07666,P23246,Q96JJ3 4 +Transcription coupled nucleotide excision repair tc ner 0.180540991919045 0.0046834791461722 0.9962631379597624 1.0 1.0 50 P23193,P05114,Q9ULR0,Q9UBW8,Q99627,P49916,P24928,P18887,Q13620,Q9H9Q2,Q9UNS2,P35251,Q9NRF9,P32780 14 +Infection with mycobacterium tuberculosis 0.1627523999276904 0.0013305396340652 0.9989383832816794 1.0 1.0 15 P23246,O14964 2 +Response of mtb to phagocytosis 0.1627523999276904 0.0013305396340652 0.9989383832816794 1.0 1.0 15 P23246,O14964 2 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2297cc7846e70a70609380be8a741c2cb1635e25 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Common pathway of fibrin clot formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of particulate exogenous antigens phagosomes", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective b4galt1 causes b4galt1 cdg cdg 2d", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective ext2 causes exostoses 2", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective lfng causes scdo3", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr3a mediated il10 synthesis", "Fertilization", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose catabolism", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interaction with cumulus cells and the zona pellucida", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna editing c to u conversion", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of tcf dependent signaling by dvl interacting proteins", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O glycosylation of tsr domain containing proteins", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of fzd by ubiquitination", "Regulation of gene expression by hypoxia inducible factor", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Release of hh np from the secreting cell", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 hd domain mutants in cancer", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis of wybutosine at g37 of trna phe", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Terminal pathway of complement", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldl clearance", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "ALYREF", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "APLP2", "APOBEC3C", "APOC1", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP5", "ARMCX3", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAT2", "BCKDK", "BCR", "BCS1L", "BECN1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRIP1", "BSG", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CABIN1", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CENPE", "CENPH", "CENPK", "CENPP", "CENPU", "CEP131", "CEP250", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTB", "CLTC", "CLU", "CMAS", "CMPK1", "CNDP2", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COLEC12", "COLGALT1", "COMMD2", "COMMD6", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ3", "COTL1", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CWC27", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DENND4C", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPY30", "DPYSL2", "DPYSL5", "DSC3", "DSE", "DSG2", "DSP", "DST", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD2", "EFTUD2", "EHD1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM3C", "FAM49B", "FAM91A1", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNBP1", "FNTA", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC1", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLTP", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILK", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INCENP", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS9", "IPO5", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRS4", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP2", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC1", "LRRC41", "LRRC8A", "LRRC8C", "LRSAM1", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LZTFL1", "M6PR", "MAD1L1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARC2", "MARCKS", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "METAP1", "METAP2", "METTL1", "MFAP1", "MFN2", "MGAT1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON1A", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MPV17", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTERF3", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO6", "NAA16", "NADK2", "NADSYN1", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAX6", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCK2", "PCM1", "PCMT1", "PCNA", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PDZD11", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPO", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUS1", "PUS7", "PWP2", "PXMP2", "PXMP4", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFT1", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMI1", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP36", "RRP7A", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCO1", "SCO2", "SCOC", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A10", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORBS3", "SORD", "SORT1", "SPAG9", "SPAST", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX18", "STX4", "STX5", "STX6", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SV2A", "SYMPK", "SYNE2", "SYS1", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAP1", "TAPBP", "TARS", "TARS2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TCEA1", "TCP1", "TCTN3", "TDRKH", "TECR", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM126B", "TMEM30A", "TMEM59", "TMEM87A", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNFAIP8", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM20", "TOMM22", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TRMT61A", "TRMU", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TSR1", "TSTA3", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBIAD1", "UBQLN1", "UBR4", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFD1", "UFL1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WBP11", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WLS", "WNK1", "WRN", "WTAP", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCRB1", "ZFYVE16", "ZMYM2", "ZNF512B", "ZNF638", "ZW10", "ZWILCH"], 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sha256:c37f328572279881730f2a58b0f0c5d9dd8a82215ff5347e62e2ee696b1e73bd +size 146037 diff --git a/msigdb_wp/consensus.joblib b/msigdb_wp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..457cffc78425aff0d62f1537ee5569399ad5817c --- /dev/null +++ b/msigdb_wp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fa2f0cac6796a61b8650ec60888eecd9c940c70b93b52870260465d732620f0f +size 109141 diff --git a/msigdb_wp/df_merge.tsv b/msigdb_wp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0e8d34414d74dd264c254aa64976130ffdf7274b --- /dev/null +++ b/msigdb_wp/df_merge.tsv @@ -0,0 +1,15 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Cytoplasmic ribosomal proteins 31 76 3.6749672677857874 0.0002378799099149 37.88106796116505 74.60194174757281 -1.2114565348655126 0.3153680511516359 14.36226619031951 1.4436994404226102 2.072543722473557 0.3695037094755983 1.0 0.0663917661810799 2.014944630575692e-05 0.0002460346086579 3.569742231312813e-09 +Primary focal segmental glomerulosclerosis fsgs 7 22 2.864834790418802 0.0041722685512248 4.497572815533981 18.5995145631068 -0.0498192290963992 0.5829800426962075 3.120165220301555 1.925127598162104 0.8734481917322797 0.2898073783973391 1.0 0.2486824788491954 0.4363210249842685 0.0028506301979692 0.0067400711985061 +Focal adhesion 11 41 2.720025132324209 0.0065276954786663 11.682038834951456 34.16990291262136 -0.7911963712605045 0.4729395257736911 4.751940607001778 4.933565144914753 1.0590469675397929 0.3584964263512231 1.0 0.0251810229681786 0.1330503697063572 0.0393100053011915 0.0500122262489322 +Smc1smc3 role in dna damage cornelia de lange syndrome 4 8 2.681737735106979 0.0073240853704739 4.927184466019417 8.106796116504855 -0.7805020719804482 0.410063737085196 2.070256031010042 1.0183998619500447 0.8525057638872805 0.3051477048107041 1.0 0.0526645480715484 0.0049445172385496 0.0020770710993276 9.75534858956266e-05 +Mrna processing 50 102 2.5804266015477064 0.0098678330668702 33.91990291262136 101.1019417475728 -0.5295625237311715 0.5689787072622147 12.879798737734788 4.3055953792039245 1.187736408487459 0.3637876503354037 1.0 0.4584356988059179 0.033448252195247 0.08427721717688 0.0073154070839396 +Atm signaling pathway 4 13 2.57512971473123 0.0100202499873802 5.725728155339806 14.978155339805824 -0.4845531915333449 0.565875901017388 3.04895624411497 2.0519960670928907 0.732253277081457 0.2994249617469091 1.0 0.1665759675679584 0.0507931717892238 0.0614466713794848 0.0324377486516598 +Met in type 1 papillary renal cell carcinoma 5 21 2.5305559585199724 0.0113881917713696 6.614077669902913 19.62135922330097 -0.2595188610963719 0.5831956753680716 3.5953173258530375 2.80556487521085 0.8254112986130796 0.2993877791725989 1.0 0.2336798458054532 0.0981876870196897 0.3833676775949033 0.0465202107555725 +Splicing factor nova regulated synaptic proteins 7 18 2.514274160784144 0.0119277669221915 4.776699029126213 15.150485436893204 -0.2758516323768686 0.5913314208771131 2.7489875941720214 2.1125318995193765 0.7784992183301543 0.2875817435057189 1.0 1.0 0.2489059409173845 0.0051734340414022 0.002368909886278 +Interactome of polycomb repressive complex 2 prc2 3 8 2.4264399966808705 0.0152477715114021 2.4635922330097086 5.33252427184466 -0.3846485455187718 0.4906283323474871 1.507629370622294 1.7841291794661418 0.9284892944142894 0.2986334793687703 1.0 1.0 1.0 0.000508984722673 0.0063533232968262 +Regulation of actin cytoskeleton 19 39 2.3088154344663003 0.0209538251776786 12.116504854368932 36.86407766990291 -0.1169230155086181 0.602158023526858 7.195671529109066 4.9952376226350585 0.9485534233323772 0.3286529451361759 1.0 0.4018208263035032 0.6430935383041047 0.4713767182287368 0.1344056922421214 +Atm signaling in development and disease 6 22 2.1272813536662483 0.0333967130937911 7.016990291262136 23.0 -0.4249256129898063 0.5657257044475777 3.6586382248180698 2.204364602548969 0.8177717925156771 0.3135177022030809 1.0 0.2027885470531376 0.0746250944081647 0.1025929503981289 0.0232948805615619 +Fas ligand pathway and stress induction of heat shock proteins 6 13 2.116734935059052 0.0342823501394937 5.053398058252427 14.822815533980584 -0.4554743114979069 0.5253434329066327 2.5660333762738876 2.3627702670603266 0.8576942488227776 0.3061103839111958 1.0 1.0 1.0 0.6209197844592236 0.0396063215160503 +Dna irdouble strand breaks and cellular response via atm 7 23 2.112175185814283 0.0346714260486247 8.633495145631068 24.00728155339806 -0.5838177568182585 0.5020952376762227 5.3620515217425035 3.2339889985987553 0.9680404168085578 0.3389282067924754 1.0 0.2486824788491954 0.1106573079891401 0.1696751373461712 0.0219335059982234 +Mecp2 and associated rett syndrome 6 21 1.994625064572252 0.0460837877956061 5.592233009708738 20.259708737864077 0.3268423909291167 0.6185500925876379 2.618777945204404 2.325048890314102 0.8108267988896323 0.3183114931796179 1.0 1.0 1.0 0.3568501183857085 0.0365963272398627 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8acc25ca3cf9ee6a892e1edc671a0dd29fe2eae6 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 610, + "title": "Average number of proteins per term", + "value": 11.52295081967213 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5c63079f0848292f3364a86866b6caaec56c3c37 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f477c1f8bd08f2812c62097cd53a3f3de746bc8c --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,188 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cytoplasmic ribosomal proteins 0.4518414442223017 3.6749672677857874 0.0002378799099149 0.1350849688637222 0.1153970111668166 76 P62913,P83731,P61247,P26373,P50914,P62917,P84098,P62841,Q02878,P62861,P47914,P46776,P46778,P62753,P61254,P62424,P62750,P62273,P62081,P62899,P46777,P62857,P39019,P46779,P61353,P46782,P62263,P36578,P83881,P05387,P40429 31 +Primary focal segmental glomerulosclerosis fsgs 0.5980778017433521 2.864834790418802 0.0041722685512248 0.9219501861725622 0.1153970111668166 22 P46013,Q9Y5K6,P11047,P19022,P35579,P46939,Q9Y490 7 +Focal adhesion 0.4711970848455022 2.7200251323242095 0.0065276954786663 0.98159158485528 0.1373066979995343 41 Q9Y490,Q13464,Q9NWH9,P11047,O14974,Q14315,O75369,O96013,P21333,P07942,P18206 11 +Smc1smc3 role in dna damage cornelia de lange syndrome 0.7960796228642142 2.681737735106979 0.0073240853704739 0.988713334362504 0.1489230691996362 8 O60934,Q92878,Q14676,Q14683 4 +Mrna processing 0.3869201805030872 2.5804266015477064 0.0098678330668702 0.9976404258354532 0.1852663690009787 102 P62316,P24928,O95319,P38159,Q01081,Q13247,P09012,O94906,P52756,Q15233,Q05048,P26599,Q13243,Q13435,O75400,P52272,Q8IX01,Q13523,Q9P2I0,O43172,P62314,P22626,P08579,P09661,P61011,P62304,Q00839,P09651,P23246,O95400,Q08170,P08621,Q96I25,Q14498,O43395,Q15287,Q96SB4,Q01130,Q9UHI6,O75494,P55769,Q92499,O60942,P33240,O00267,O75937,O94992,P84103,Q15459,Q14683 50 +Atm signaling pathway 0.6722434131245675 2.57512971473123 0.0100202499873802 0.997851923016152 0.1852663690009787 13 O60934,P16104,Q92878,Q14676 4 +Met in type 1 papillary renal cell carcinoma 0.5649813744205124 2.5305559585199724 0.0113881917713696 0.9990758679722804 0.1984799137295849 21 Q92733,O43815,Q9NWH9,Q14241,P62913 5 +Splicing factor nova regulated synaptic proteins 0.591538901914564 2.5142741607841437 0.0119277669221915 0.9993376250929497 0.2021093839593568 18 Q9BY67,O43491,Q9Y2J2,P27816,Q13573,P19022,P20020 7 +Interactome of polycomb repressive complex 2 prc2 0.7455848094614914 2.4264399966808705 0.0152477715114021 0.9999149933119774 0.2325285155488821 8 Q9Y2W1,Q9NYF8,Q16576 3 +Regulation of actin cytoskeleton 0.4376473922316268 2.3088154344663003 0.0209538251776786 0.999997545648742 0.2778659425735644 39 Q9Y281,Q13464,P46108,P46940,P26038,P18206,Q13177,P35241,Q92888,P15311,O14974,O00443,Q9Y6W5,Q8N8S7,P35580,O60610,Q9UQB8,O75116,O96013 19 +Atm signaling in development and disease 0.5038462896843219 2.1272813536662483 0.0333967130937911 0.9999999989966712 0.3845376343574742 22 P16104,O60934,P42345,Q14676,Q92878,Q14683 6 +Fas ligand pathway and stress induction of heat shock proteins 0.5979075288705207 2.1167349350590516 0.0342823501394937 0.9999999994264082 0.3845376343574742 13 Q13177,Q9UER7,P09874,P02545,Q13813,Q03252 6 +Dna irdouble strand breaks and cellular response via atm 0.4924712753704466 2.112175185814283 0.0346714260486247 0.9999999995514112 0.3845376343574742 23 P16104,Q9UQE7,P09874,O60934,Q14676,Q92878,Q14683 7 +Nipbl role in dna damage cornelia de lange syndrome 0.9005211188954427 2.074035146071455 0.0380760468807781 0.9999999999480182 0.3947562386694572 4 P16104,Q14676 2 +Mecp2 and associated rett syndrome 0.4962052037206851 1.9946250645722516 0.0460837877956061 0.9999999999996828 0.4324786239279964 21 O75475,Q15910,Q9UQE7,P42345,P51608,P62753 6 +Base excision repair 0.4890064893248954 1.8743177172039884 0.0608866469728273 1.0 0.5082327104661412 20 P09874,P18887,Q9NRF9,P39748,Q96T60 5 +Regulation of sister chromatid separation at the metaphaseanaphase transition 0.589981997208178 1.872543194002952 0.0611314919312213 1.0 0.5082327104661412 11 Q9Y6D9,Q14683,Q12834 3 +Homologous recombination 0.6845304458776957 1.8698647350194335 0.061502604025786 1.0 0.5082327104661412 7 Q92878 1 +Inflammatory response pathway 0.943495038588762 1.8661962654471729 0.0620139113937403 1.0 0.5082327104661412 2 P07942 1 +Ddx1 as a regulatory component of the drosha microprocessor 0.7826715704050915 1.833925807955387 0.0666650080231836 1.0 0.5144725359117774 5 O60934,Q92878 2 +Cytosine methylation 0.7815172413792725 1.8288356434661823 0.067424233597451 1.0 0.5144725359117774 5 O75874,P26358,P51608,P48735 4 +Tumor suppressor activity of smarcb1 0.4930286738240801 1.7944639135848943 0.0727391534601329 1.0 0.5322254608259446 18 P42771,Q15910,P84243,Q96GM5,Q8TAQ2,Q969G3,Q92922,Q92785,Q12824,P11802,O14497 11 +Ciliopathies 0.4271507278927132 1.7109013264328357 0.0870993297257793 1.0 0.570161161358862 25 Q13049,Q9Y366,Q15051,O15078 4 +Tgfbeta signaling pathway 0.3890351403025578 1.7032749085573278 0.0885166339331715 1.0 0.570161161358862 36 Q13464,P49790,Q9NWH9,Q13573 4 +Dna irdamage and cellular response via atr 0.3870485228517831 1.6821778783339725 0.0925343524172579 1.0 0.570161161358862 36 P16104,O60934,Q14676,Q92878,P39748,Q14683 6 +Preimplantation embryo 0.6443783128776963 1.6660642890325632 0.0957006103258018 1.0 0.5779937851360306 7 Q9P0M6,Q92945 2 +Androgen receptor signaling pathway 0.3900764504458558 1.5534278394879406 0.1203209562395857 1.0 0.6334976791357885 28 Q96ST3,Q9UER7,Q13464,P21333,Q96EB6,O75116,Q5VUA4 7 +Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.619874751241808 1.540340349955823 0.1234774131345517 1.0 0.6334976791357885 7 Q07157,P27361,P06756,P12814,P18206 5 +Endoplasmic reticulum stress response in coronavirus infection 0.5447618883730369 1.5351376132850925 0.1247500288090515 1.0 0.6334976791357885 10 Q15435,Q96QC0,O14974 3 +Retinoblastoma gene in cancer 0.3397729014230189 1.5150720929682615 0.1297541480386663 1.0 0.6334976791357885 51 Q96ST3,Q14527,P26583,Q16576,O75446,P25205,Q9UQE7,P26358,O00311,P00374,P16949,O95347,P33991,P11802,Q14683 15 +Hair follicle development cytodifferentiation part 3 of 3 0.763054282034362 1.5033886926414504 0.1327388407114318 1.0 0.6334976791357885 4 P78536 1 +Effect of progerin on genes involved in hutchinsongilford progeria syndrome 0.4862146115096704 1.5007950480604764 0.1334085798865112 1.0 0.6334976791357885 14 P45973,P84243,Q16576,Q14839,Q13185,O95983,O94776 7 +Mitochondrial gene expression 0.5685303841073868 1.4777121430297104 0.1394848427705484 1.0 0.639862517802268 8 P51610,Q8WVM0,Q00059 3 +H19 action rbe2f1 signaling and cdkbetacatenin activity 0.7011743035076387 1.470315895981788 0.141476217803399 1.0 0.639862517802268 5 Q16527,P11802,Q15648 3 +Histone modifications 0.5440236378813793 1.4308071138685028 0.1524855037028292 1.0 0.639862517802268 9 Q15910,Q96L73 2 +Nad metabolism sirtuins and aging 0.7314210687011916 1.369545496976216 0.170828823206719 1.0 0.6522399771596169 4 P09874,Q96EB6 2 +Onecarbon metabolism 0.4659531211580457 1.3619368038781088 0.1732178299997671 1.0 0.6522399771596169 14 P11586,P13995,P26358,P00374,Q6UB35,P04818,Q9NZL9 7 +G13 signaling pathway 0.4487858896322551 1.354470978028256 0.1755861663788458 1.0 0.6527599993187824 15 Q9Y281,Q13464,Q92888,O75116,O60610 5 +Genes controlling nephrogenesis 0.5443508192919866 1.3434304061308475 0.1791326467513698 1.0 0.6527599993187824 8 Q9Y5K6,P11047 2 +Malignant pleural mesothelioma 0.2927565527303783 1.3411193159123036 0.1798817168529973 1.0 0.6527599993187824 78 Q9NWH9,P11802,P07942,Q02241,Q4VCS5,Q13043,P19022,P62753,P25490,P23588,Q9Y6D9,P05114,Q15910,Q99496,P11047,Q9HCK8,P11166,P42345,P51610,P67870,O96013 21 +Transsulfuration and onecarbon metabolism 0.4273127280054006 1.3383725829227204 0.1807750117635971 1.0 0.6527599993187824 19 P11586,P13995,P26358,P00374,Q6UB35,P04818,Q9NZL9,P31153,P32929 9 +Extracellular vesiclemediated signaling in recipient cells 0.7216884997451678 1.3283007202977808 0.1840787818900864 1.0 0.6527599993187824 4 Q9NWH9 1 +1q211 copy number variation syndrome 0.5084092717991975 1.3175525744335908 0.1876534704735912 1.0 0.6532098030535336 10 Q16625,Q07157,Q9UDY2 3 +Egfr tyrosine kinase inhibitor resistance 0.4580792685177652 1.3079170072570585 0.1909014603199539 1.0 0.6562133575257213 14 Q9NWH9,P62753 2 +Joubert syndrome 0.4172893505429507 1.304697668156564 0.1919958158274353 1.0 0.6562133575257213 20 P09874,Q9UM54,P42345,P21333,Q92878,O15078 6 +Endoderm differentiation 0.3566457306628654 1.2780716902436706 0.2012241497579312 1.0 0.678158736753249 32 P11940,Q15910,P11047,Q9BV73,Q92541 5 +Pathogenic escherichia coli infection 0.3941471806973665 1.2170456883747358 0.2235868330759658 1.0 0.7106713170086298 22 P59998,Q13464,P19338,Q16625,P15311,Q92974,Q14247 7 +Ectoderm differentiation 0.3922326566753131 1.2010417868406842 0.2297349923624962 1.0 0.7245474134351214 22 P26583,A1A4S6,P17480,Q14980,P51608,Q9P2E9 6 +Hippomerlin signaling dysregulation 0.3915296402939656 1.1951680331893453 0.2320213853901638 1.0 0.7258104876307688 22 P19022,Q9NWH9,O14974 3 +Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma 0.4864764014627162 1.1860896306233295 0.2355869050914161 1.0 0.730897699645497 10 P16104,Q99496,Q15910 3 +Nephrogenesis 0.8119658119658106 1.1849328162193418 0.2360440111969883 1.0 0.730897699645497 3 O95747,O94788 2 +Pi3kakt signaling pathway 0.3245282535015416 1.1558003098174685 0.247762846295972 1.0 0.7501724364863988 44 P13807,P23588,Q9NWH9,Q16513,P42345,P62753,P11047,Q16543,P11802,P07942 10 +Intraflagellar transport proteins binding to dynein 0.4906794146676007 1.1233491852447748 0.2612892221235041 1.0 0.752114184998952 9 Q13409,Q8NCM8,O43237 3 +Alpha 6 beta 4 signaling pathway 0.4657026667292275 1.11196269216891 0.2661541915424421 1.0 0.752114184998952 11 P11047,P07942 2 +Envelope proteins and their potential roles in edmd physiopathology 0.4044465746372609 1.0611219829359857 0.2886344687524995 1.0 0.7894508253196046 16 P42167,P42166,P28482,Q14739,Q9Y2U8,P27361,P62993,Q15149,P50402,P33176 10 +Epithelial to mesenchymal transition in colorectal cancer 0.355257836549263 1.0583482645396094 0.2898966965108056 1.0 0.7894508253196046 25 Q15910,Q07157,Q16625,Q8TB37,P19022,Q8N3R9 6 +Arrhythmogenic right ventricular cardiomyopathy 0.4182803491473981 1.0360636520811528 0.3001724480803118 1.0 0.8030929531973255 14 P17301,P19022,P02545,P35221,Q14126,P50402,P12814,O43707 8 +Dna damage response 0.3817259255850386 1.0224689292357902 0.3065590110513385 1.0 0.8060387790573987 20 O60934,P16104,Q92878 3 +Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms 0.4857686002189029 1.0185894009920755 0.3083979382263442 1.0 0.8073937438543775 8 Q13177,Q13043,O96013 3 +Mirna regulation of dna damage response 0.374618823626326 1.0079104957230476 0.3134974324885906 1.0 0.8137592928427246 21 O60934,P16104,Q92878 3 +Glioblastoma signaling pathways 0.390857602342558 0.9888456998443828 0.3227386410308503 1.0 0.8271872732303308 17 P11802,P42771,P52701,Q9NWH9,P27361,P62993,O00443,Q05655 8 +Pentose phosphate pathway in senescent cells 0.588421963871854 0.9629834924768672 0.3355558074537366 1.0 0.8463671984584914 5 P11413,P29401,O95336 3 +Cellular proteostasis 0.5876139699675182 0.959398008126275 0.3373582781757309 1.0 0.8463671984584914 5 O15212 1 +Disruption of postsynaptic signaling by cnv 0.4740369345262035 0.9542949440164504 0.3399343665939842 1.0 0.8463671984584914 8 P27361,Q06787,Q07157,Q14168 4 +Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence 0.4167722153304279 0.938776394030434 0.3478455612249682 1.0 0.852365220206972 13 P17096,P11166,P09874 3 +Prion disease pathway 0.5023271996617704 0.9341495316414282 0.3502267648052068 1.0 0.8545533061247047 7 P27361,P14625,P30101,Q9UQE7 4 +Nucleotide metabolism 0.3886786445850148 0.9275939699692382 0.353618226814957 1.0 0.8559806284012849 15 P00374,P13995 2 +Tca cycle aka krebs or citric acid cycle 0.3843994791730707 0.9175281225857668 0.358865963223826 1.0 0.8586637226620278 16 O43837,P31040,P09622,Q96I99,P53597,P36957,P48735,Q99798 8 +Dna repair pathways full network 0.2899496048079719 0.9001066960759574 0.3680634729156864 1.0 0.8661816250518557 55 P16104,P09874,O60934,P20585,P18887,Q92878,Q9NRF9,P39748,Q96T60 9 +15q112 copy number variation syndrome 0.6194142399363961 0.8984596270374862 0.3689405598991424 1.0 0.8661816250518557 4 Q96CW5,Q9BSJ2 2 +Bladder cancer 0.5731098212263508 0.895327324102488 0.3706121379320235 1.0 0.8661816250518557 5 P11802,P42771,P28482 3 +Complement system 0.4064230542938997 0.8724815026312348 0.3829457548574053 1.0 0.8840326488463556 13 P11047,P07942 2 +Pathways affected in adenoid cystic carcinoma 0.3718987147019145 0.8515919241205748 0.3944406234622564 1.0 0.8840326488463556 17 P10412,Q6ZRS2,Q96L73 3 +Mfap5mediated ovarian cancer cell motility and invasiveness 0.5987990344134952 0.8141929003357817 0.4155344520398158 1.0 0.8872831030219805 4 P27361,P06756 2 +Integrinmediated cell adhesion 0.3139317557852616 0.8133885658811957 0.4159953128791978 1.0 0.8872831030219805 27 Q13177,Q9Y490,Q13464,P46108,O96013,P06756,P17301,Q15942,O75116,P62993,P18206 11 +Nad metabolism 0.7127176399922239 0.8081907930908089 0.4189807570412482 1.0 0.8872831030219805 3 P09874 1 +Insulin signaling in adipocytes diabetic condition 0.5967547108117911 0.8059154833737726 0.4202915829072975 1.0 0.8872831030219805 4 P42345,P62753 2 +Insulin signaling in adipocytes normal condition 0.5967547108117911 0.8059154833737726 0.4202915829072975 1.0 0.8872831030219805 4 P42345,P62753 2 +Transcription cofactors ski and skil protein partners 0.5908865824723202 0.7822449603934812 0.4340706262708549 1.0 0.8945374392743969 4 P51608 1 +Proximal tubule transport 0.4024339554769786 0.7757888676867479 0.4378736580264672 1.0 0.8963185617320304 12 P11166,P05026,P04920 3 +Microtubule cytoskeleton regulation 0.3516980505774226 0.7598934953913855 0.4473182500288897 1.0 0.9037573617122328 19 Q9Y281,P46821,Q13464,Q99661,P16949,O60610 6 +Oxysterols derived from cholesterol 0.4359907457026033 0.7500846475672285 0.4532037252699812 1.0 0.9048576095024892 8 P34913,Q9UBM7 2 +Hippo signaling regulation pathways 0.3602253844702737 0.7489087968050098 0.4539121778815764 1.0 0.9048576095024892 16 P42345,P19022,Q9NWH9 3 +Arachidonate epoxygenase epoxide hydrolase 0.668412348401316 0.717766081969502 0.4729015301037682 1.0 0.9204850890577828 2 P34913 1 +Nocgmppkg mediated neuroprotection 0.5697738554881367 0.6983172219334713 0.4849788312891507 1.0 0.9204850890577828 4 Q08752,Q15334,P07196 3 +Praderwilli and angelman syndrome 0.4255547990549442 0.6957276821855578 0.4865993860097761 1.0 0.9204850890577828 8 P42771,Q15154,P11802,O95714 4 +Ketogenesis and ketolysis 0.453111374575666 0.6900626266872806 0.4901548045734516 1.0 0.9204850890577828 7 O43772 1 +Airway smooth muscle cell contraction 0.5644675815569834 0.6775678510784938 0.4980457357624077 1.0 0.9204850890577828 4 Q13464 1 +Nongenomic actions of 125 dihydroxyvitamin d3 0.4067506710185817 0.6555396799282995 0.5121203475476728 1.0 0.9204850890577828 9 Q96JM3 1 +Vasopressinregulated water reabsorption 0.3394853549811908 0.647073711091291 0.5175842386013434 1.0 0.9204850890577828 18 Q13409,Q12846,Q14203,O43237,Q9Y6G9,P61020,Q8NCM8 7 +Chromosomal and microsatellite instability in colorectal cancer 0.3383433049910538 0.6191495009822833 0.5358178757980989 1.0 0.9332906678722142 17 P20585 1 +Orexin receptor pathway 0.3276686965555468 0.6146711563203132 0.5387719119903731 1.0 0.9332906678722142 20 P11166,P20290,Q00059,P17096,Q9H4L5,Q9P0J1 6 +Hedgehog signaling pathway wp47 0.6400220507166658 0.6102246351216205 0.5417130128620387 1.0 0.9332906678722142 2 Q96ST3 1 +Metabolic reprogramming in colon cancer 0.2834344793728474 0.6093491499644219 0.5422930353053776 1.0 0.9332906678722142 36 P00558,Q15758,Q99798,Q96C36,P29401,P11166,P32322,P18669,Q96I99,P06733,P11177,P36957,P14618,P48735,P04406,P00505 16 +Mirna regulation of prostate cancer signaling pathways 0.4030758258481113 0.5821200641743702 0.5604858112662425 1.0 0.9544900274158108 8 P42345 1 +Vitamin dsensitive calcium signaling in depression 0.428150971418549 0.5727531889874067 0.5668118182639417 1.0 0.9544900274158108 7 P23634,P11413,P20020 3 +Focal adhesion pi3kaktmtorsignaling pathway 0.2666702807482964 0.5522361112944957 0.5807865963441097 1.0 0.9706296541641284 46 P23588,P11166,Q9NWH9,P11047,P07942,P62753 6 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.3525635546214776 0.5448922072653124 0.5858276561719251 1.0 0.9737189925473416 13 Q96AY3,P50454,Q5JRA6,Q32P28,Q02809 5 +Ovarian infertility 0.6154906284454239 0.5218278292869656 0.6017902114045637 1.0 0.9871373205550336 2 P11802 1 +Ncrnas involved in wnt signaling in hepatocellular carcinoma 0.3480203848400708 0.5192158925060305 0.6036101976508648 1.0 0.9871373205550336 13 Q9HCK8 1 +Ebola virus infection in host 0.265914303004339 0.5094471431165699 0.6104388389371667 1.0 0.989918773784816 43 P01889,O75569,P11387,P17301,Q9H269,P21333,P09496,Q14315,P30511,P46940,O75369,P78536,P27361,P35251,Q9UN37,P12814,O43707 17 +Gastric cancer network 1 0.3659899994373283 0.5009808546638452 0.6163845970563018 1.0 0.992070195789826 10 P33991,P62805,P84243,Q9ULW0 4 +Tp53 network 0.603914002205062 0.4818401931910377 0.6299194744170202 1.0 1.0 2 P42771 1 +Ccl18 signaling pathway 0.3525071729589392 0.4601780421564657 0.6453884305317019 1.0 1.0 11 P19022,P27144,P11166 3 +White fat cell differentiation 0.5915104740904028 0.4403765054436651 0.6596644384046071 1.0 1.0 2 P35221 1 +Ras signaling 0.2700859828442293 0.4399411240853984 0.6599797499183195 1.0 1.0 28 Q9NWH9,P55196,Q13043,Q96KP1,O96013,P61020 6 +Rett syndrome causing genes 0.3122169986608218 0.4335297277560817 0.6646299740949331 1.0 1.0 15 P51608 1 +Vitamin b12 disorders 0.497242140099274 0.4313121052592196 0.6662414496142126 1.0 1.0 4 Q99707,P22033,Q96EY8 3 +Type 2 papillary renal cell carcinoma 0.3601724848377168 0.4239818449135089 0.6715790537222903 1.0 1.0 9 Q92733,P23246,P11166 3 +Small cell lung cancer 0.3101733583903617 0.4219674815461055 0.6730487531727918 1.0 1.0 15 P07942 1 +P38 mapk signaling pathway 0.3588606264238749 0.4179617240453509 0.6759751024459397 1.0 1.0 9 Q9UER7,P05114 2 +Male infertility 0.2871044736222243 0.417519458976104 0.6762984941990513 1.0 1.0 23 P11586,P18074,P09874,P17096,Q9UHI6,P54098,P13010,P04179,P35251,P40818,P62805 11 +Prolactin signaling pathway 0.2920611557950447 0.3998736297638466 0.689249595900767 1.0 1.0 21 P51956,P21333,P62753 3 +Folatealcohol and cancer pathway hypotheses 0.5724917309812458 0.3798432449494328 0.7040617791071391 1.0 1.0 2 Q99707 1 +Transsulfuration pathway 0.3577973985812456 0.3736021496169904 0.7087003344090812 1.0 1.0 8 P26358,Q99707,Q9NZL9,P32929 4 +Mapk signaling pathway 0.2532786966060221 0.3726530847849787 0.7094066580999723 1.0 1.0 39 Q9UER7,P0DMV9,P16949,P54652,Q13043,Q14315,O75369,P21333,P11142 9 +Glucuronidation 0.4036975717439379 0.3665388711418023 0.7139630127052752 1.0 1.0 6 O95394,P36871,Q96G03,Q16851,P19367 5 +Head and neck squamous cell carcinoma 0.2963427787044173 0.3530900581280058 0.7240209259549344 1.0 1.0 16 P42345,P11802,Q04721,P62753 4 +22q112 copy number variation syndrome 0.2531748267100143 0.3357135669557482 0.7370868740660035 1.0 1.0 34 Q9NQ50,P24928,O95721,Q96DF8,O96013,P43487,O94788,P62805 8 +Caloric restriction and aging 0.4268297277203902 0.3189914499221541 0.7497329963430135 1.0 1.0 5 P42345 1 +Novel intracellular components of rigilike receptor rlr pathway 0.3066245744903414 0.3070584229542328 0.7587989035884384 1.0 1.0 13 Q13526,Q13573 2 +Krebs cycle disorders 0.3599227159812483 0.2919278459360533 0.7703417923959925 1.0 1.0 7 P07954,Q96I99,P53597,O00330,Q96HY7,P36957 6 +Serotonin receptor 2 and elksrfgata4 signaling 0.5515662164315924 0.2907873384799653 0.7712139695432079 1.0 1.0 3 P27361 1 +Serotonin receptor 467 and nr3c signaling 0.5515662164315924 0.2907873384799653 0.7712139695432079 1.0 1.0 3 P27361 1 +Sarscov2 innate immunity evasion and cellspecific immune response 0.3171384923474869 0.2774755867708679 0.7814149490750686 1.0 1.0 10 Q7Z434 1 +Regulatory circuits of the stat3 signaling pathway 0.3332497133785766 0.2762004555721171 0.7823941073437637 1.0 1.0 8 P16949 1 +Pyrimidine metabolism 0.2354013160201721 0.2632733118785037 0.7923399283225803 1.0 1.0 45 Q05682,O14802 2 +Amyotrophic lateral sclerosis als 0.3128723718583913 0.2606640576618669 0.7943515858585484 1.0 1.0 10 Q9UER7 1 +Il9 signaling pathway 0.3441898978746952 0.2386304150148118 0.8113921785821456 1.0 1.0 7 P28482,P42224,Q02750,P62993,P50750,P27361 6 +Pdgfrbeta pathway 0.3441898978746853 0.23863041501478 0.8113921785821703 1.0 1.0 7 P19525,Q02750,P19174,P42224,P27361,P62993 6 +Thyroid hormones production and peripheral downstream signaling effects 0.2705475925867157 0.2326724686579937 0.8160157493503621 1.0 1.0 17 Q7LBC6,P62753 2 +Regucalcin in proximal tubule epithelial kidney cells 0.3615580255679075 0.2257557542992941 0.821391391612375 1.0 1.0 6 Q13283 1 +Breast cancer pathway 0.2418721482841079 0.2167228480151152 0.8284243410158336 1.0 1.0 26 P09874,O60934,P42345,Q04721,P67870,Q92878 6 +Somatroph axis gh and its relationship to dietary restriction and aging 0.5194609845685424 0.2151856595940312 0.829622571031315 1.0 1.0 3 P42345 1 +Cori cycle 0.2859269659042032 0.1917656872353398 0.8479257497068651 1.0 1.0 12 P11166,P18669 2 +Canonical and noncanonical notch signaling 0.5063178496241116 0.1877704603961363 0.8510565930397671 1.0 1.0 3 P55081 1 +Development of ureteric collection system 0.4123000551571963 0.1876884100474445 0.8511209162506415 1.0 1.0 4 P05556,P35222,O94813 3 +Pentose phosphate metabolism 0.3801648880572095 0.1862176215264753 0.8522741056693084 1.0 1.0 5 P29401,O95336 2 +Mir517 relationship with arcn1 and usp1 0.4942116868798094 0.1774790300460904 0.859132135356141 1.0 1.0 2 P48444 1 +Type ii interferon signaling ifng 0.3218287685655216 0.1721012762628052 0.8633579094222088 1.0 1.0 7 P01889,Q05655,P62805 3 +Robo4 and vegf signaling pathways crosstalk 0.4796030871003161 0.1491320305876136 0.8814494517399383 1.0 1.0 2 O94813 1 +Vegfavegfr2 signaling pathway 0.2791044274698162 0.1488644419668769 0.8816605997191993 1.0 1.0 183 Q13464,P04083,O60885,P31948,P36543,O75347,P46940,Q14157,Q9UG63,P48735,Q9Y4L1,P18206,O43852,Q14241,Q4VCS5,P15311,P31689,Q96PU8,Q9Y520,Q9Y5S2,Q01844,P62753,P61254,P49257,P19338,Q9UM54,Q15075,O14964,Q8NBS9,Q9NYL9,O75369,P46777,P55036,Q96CT7,P35579,P61353,Q5VU43,Q14498,P11940,P29401,Q00059,Q12849,P05387,P42345,Q16625,P55196,Q9UNL2,O75116,P40429,O00159 50 +Cytosolic dnasensing pathway 0.2556943000172746 0.1398965055416811 0.8887417623122968 1.0 1.0 14 Q7Z434,Q9NZI8,O14802 3 +Liver x receptor pathway 0.4721609702315216 0.1358865265498939 0.8919109869283262 1.0 1.0 2 O00767 1 +Energy metabolism 0.2497848638759233 0.1219624469390355 0.9029287591896192 1.0 1.0 14 Q8WVM0,Q15648,Q96EB6 3 +Lncrna in canonical wnt signaling and colorectal cancer 0.2393543447018816 0.1174798101217265 0.9064798424346 1.0 1.0 18 Q9HCK8 1 +Nucleotide excision repair in xeroderma pigmentosum 0.2136144188776612 0.1113940733216349 0.9113038596172804 1.0 1.0 37 P54727,P05114,P09874,P49916,Q13620,P18887,P35251,Q9NRF9,P32780,P62805 10 +Tgfbeta receptor signaling 0.3440000000000038 0.1088698856834914 0.9133056923796716 1.0 1.0 5 P62942,P35222,P42224,P27361 4 +Tgfbeta receptor signaling in skeletal dysplasias 0.3440000000000038 0.1088698856834914 0.9133056923796716 1.0 1.0 5 P62942,P35222,P42224,P27361 4 +Camkk2 pathway 0.2580432327186262 0.107232078429194 0.9146048672355152 1.0 1.0 12 P42345,Q14155,Q9Y3D6,Q96EB6,P27361,Q14683 6 +Osteoblast differentiation and related diseases 0.2634403104879771 0.1050167962972824 0.9163624808986204 1.0 1.0 10 P27361,O00443,Q04721,Q05655 4 +Egfegfr signaling pathway 0.2086081302803272 0.1005204574887495 0.9199311423648752 1.0 1.0 46 Q13464,Q92888,Q8IZP0,P16949,O14964,P40818 6 +Acute viral myocarditis 0.2403814145698951 0.0963228518817111 0.9232641622932278 1.0 1.0 14 P11940,P09874 2 +Burn wound healing 0.2670990827335996 0.087821312379284 0.9300186983814588 1.0 1.0 8 P50454 1 +Interferon type i signaling pathways 0.228397463181486 0.0844994575839736 0.9326593340857028 1.0 1.0 15 P23588,P62753 2 +Aerobic glycolysis 0.246653152680747 0.0742112431929666 0.94084229974732 1.0 1.0 11 P00558,P06733,P11166,P04406 4 +Glycolysis in senescence 0.2534646634570245 0.071879355370123 0.942697919572923 1.0 1.0 9 P00558,P11413,P06733,P14618,P04406 5 +Measles virus infection 0.211481294077421 0.0705023733361312 0.9437938116037128 1.0 1.0 25 P0DMV9,P54652,P67870,Q7Z434,P11802,P11142 6 +Cell cycle 0.2002767503991843 0.0697551510139149 0.944388544483685 1.0 1.0 52 Q13416,Q9Y6D9,Q9UQE7,Q12834,O00311,P33991,Q14683 7 +Hif1a and pparg regulation of glycolysis 0.3444518851725659 0.0686629030038995 0.9452579475966096 1.0 1.0 4 P11166 1 +Neural crest cell migration during development 0.2540402504149578 0.0644904846190556 0.9485796835148552 1.0 1.0 8 O96013 1 +P53 transcriptional gene network 0.2511083997868344 0.0598570246536538 0.9522695078458708 1.0 1.0 8 Q7LG56,P11166,P30038 3 +G protein signaling pathways 0.217402488033724 0.0589655583435243 0.9529795408190638 1.0 1.0 17 Q92888,Q02952 2 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.3339178621243032 0.0564553559814296 0.9549790595348472 1.0 1.0 4 Q15758 1 +Follicle stimulating hormone fsh signaling pathway 0.2456649273709222 0.0518213476138395 0.9586710454673268 1.0 1.0 8 P62753 1 +Pilocytic astrocytoma 0.3991179713340526 0.0464918485669886 0.9629182309639353 1.0 1.0 2 P62993 1 +Unfolded protein response 0.4030879514750429 0.046284379223305 0.9630835895400444 1.0 1.0 3 Q9Y3I0,P04637 2 +Valproic acid pathway 0.2572453767595901 0.0453501832269439 0.9638281881256224 1.0 1.0 7 P80404,P55084,P26440,P45954,Q13547,P40939 6 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.2402133768827587 0.0444914921165761 0.9645126335706355 1.0 1.0 8 O14964 1 +Metastatic brain tumor 0.3997794320374921 0.0437619010712622 0.965094196513189 1.0 1.0 3 P60953,P04637 2 +Heart development 0.3992280121312337 0.0433519063511262 0.9654210148005616 1.0 1.0 3 P35222,P28482 2 +Gastric cancer network 2 0.2077849831641021 0.0418305639918125 0.9666337697880648 1.0 1.0 16 Q8WYP5,Q03252 2 +Thymic stromal lymphopoietin tslp signaling pathway 0.2273062195133629 0.0413095471971524 0.9670491220059084 1.0 1.0 11 P62753 1 +Gdnfret signaling axis 0.3953680727874235 0.040563889962443 0.9676435720844794 1.0 1.0 3 P35222,O94813 2 +Melanoma 0.2061145088665767 0.0405452629625229 0.9676584220634225 1.0 1.0 15 P42771,P0DP25,P28482,P27361,P62993,P11802,P18206 7 +Agerage pathway 0.2004189555453003 0.0292432311545341 0.976670602487991 1.0 1.0 18 Q13464,P26038,O60610,P15311 4 +Urea cycle and metabolism of amino groups 0.2176194421430598 0.0234934133865342 0.9812566923925266 1.0 1.0 9 Q53H96,Q14353,P78540,P32322,P52788,P54886,P12277,P19623 8 +Gaba metabolism aka ghb 0.3642128480838103 0.0228729004748829 0.9817516570271588 1.0 1.0 3 P80404,O43488 2 +Erbb signaling pathway 0.1939043917203235 0.0214438797553476 0.9828915706195104 1.0 1.0 17 Q13177,P46108,P42345,O96013,P62993 5 +Il2 signaling pathway 0.2110497237568969 0.0204761093270879 0.9836635700759444 1.0 1.0 10 Q06124,P28482,P40763,P42224,Q02750,P46109,P62993,P27361,P62753 9 +Aryl hydrocarbon receptor pathway wp2586 0.2264635919280012 0.016315177792035 0.9869829490262194 1.0 1.0 7 Q16543,P28482,P07900 3 +Tca cycle nutrient use and invasiveness of ovarian cancer 0.3438103115522418 0.0152367961774109 0.9878432659602404 1.0 1.0 3 P27361,P28482 2 +Congenital generalized lipodystrophy cgl 0.311190738698998 0.0113004553973907 0.9909837330054438 1.0 1.0 2 P62993 1 +Type ii diabetes mellitus 0.2533038824114725 0.0110761026022432 0.9911627294329686 1.0 1.0 5 P42345 1 +Steroid biosynthesis 0.3165150261924406 0.0086779517656678 0.993076083169948 1.0 1.0 3 P56937,P51659 2 +Nonsmall cell lung cancer 0.1749498090437439 0.0059955649558953 0.9952162599484412 1.0 1.0 16 P42771,Q9HC35,Q13043,P62993,P11802 5 +Methionine metabolism leading to sulfur amino acids and related disorders 0.2359336545158813 0.0043446740749165 0.9965334625397452 1.0 1.0 5 Q9NZL9,P32929 2 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5363c3d8ed4b07887f9f65ac86e29d4354832274 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Arylamine metabolism", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Effects of nitric oxide", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes associated with the development of rheumatoid arthritis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna for targeting cancer growth and vascularization in glioblastoma", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthesis ii from tryptophan", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoblast signaling", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Tamoxifen metabolism", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AARS", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABHD11", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA3", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APBB1", "APEX1", "APLP2", "APMAP", "APOC1", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGAP10", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL6", "ARL8B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG5", "ATG7", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "BAG2", "BAG3", "BAG4", "BAIAP2", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BBS4", "BCAS3", "BCAT2", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BECN1", "BLM", "BLVRA", "BPTF", "BRCA1", "BRD4", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZB", "CARM1", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC7", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CEP170", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHUK", "CIP2A", "CISD1", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLPTM1L", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMPK1", "CNOT1", "CNOT9", "CNP", "COA3", "COASY", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCK", "DCP1A", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAC2", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHBP1", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "ELP4", "EMD", "EML4", "ENAH", "ENDOG", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ESD", "ESS2", "ETF1", "ETFA", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAH", "FAM120A", "FAM91A1", "FANCG", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GABPA", "GAL", "GALNS", "GALNT1", "GAMT", "GAPDH", "GART", "GBA", "GCC1", "GCC2", "GCDH", "GCLC", "GCLM", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GID4", "GID8", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLRX", "GLS", "GM2A", "GMPPB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTPBP4", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRS4", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIDINS220", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC2", "KNSTRN", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP2", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM2", "LSM7", "LSS", "LTA4H", "LZTFL1", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC2", "MARCKS", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MEPCE", "MFAP1", "MFN2", "MGST1", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOCS1", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO6", "NAA15", "NAA16", "NAA40", "NAA50", "NADSYN1", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCSTN", "ND1", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFATC2IP", "NIPBL", "NKRF", "NME1", "NME2", "NONO", "NOP2", "NOTCH2", "NPC1", "NPC2", "NRP1", "NSD1", "NSDHL", "NSF", "NT5C3A", "NTHL1", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "ORC5", "OSBPL3", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAK2", "PAK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PARVA", "PAX6", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDLIM7", "PDP1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PIBF1", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNKP", "PNP", "PNPO", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QKI", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB21", "RAB23", "RAB2A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBBP4", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOG", "RIF1", "RIPK1", "RMI1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF40", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", 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pval_50 pval_100 pval_250 pval_500 +nucleolus_gc 43 84 4.646718090556249 3.372575540838696e-06 36.907766990291265 79.67718446601941 -1.342069158093771 0.3573216441012204 12.290032185888387 4.137815641901007 1.460174227676572 0.3627524615681838 1.0 0.0013677912764436 0.0028349238604318 1.1721180165400917e-07 5.446756819932193e-12 +nuclear_punctae 38 89 4.436580857387591 9.139901295140971e-06 23.90776699029126 79.24514563106796 -0.4852599748283621 0.5985181205148213 8.910626244109409 7.228624379208315 0.8052791898597869 0.3222585891422979 1.0 0.0049315444833474 0.0025846314850103 0.0226530102624064 5.176493445165152e-05 +chromatin 46 100 3.205154246259725 0.0013499011943549 34.101941747572816 93.41019417475728 -0.8053692270324102 0.51578099344678 12.190211580015282 5.60635847071002 1.2018547509237514 0.3606661835231761 1.0 0.4637995473310806 0.0351687642431511 0.0352812339316122 0.0083389462244248 +nucleolus_fc_dfc 13 26 3.0823780170059702 0.0020535387578302 8.20873786407767 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mode 100644 index 0000000000000000000000000000000000000000..27a8ff6b5c9106301be7a75a39ecb9fb96e13823 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,12 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +nucleolus_gc 0.5091486610056858 4.646718090556249 3.372575540838696e-06 5.733223732021381e-05 5.733378419427483e-05 84 Q13823,P46013,Q9BSC4,O60869,Q9Y237,P62913,P46087,Q2NL82,Q8IY37,Q9NR30,P26373,P84098,Q66PJ3,O43709,Q9NZM5,Q12906,P62861,Q9NW13,Q9BVJ6,P35269,O15213,P06748,Q14137,Q14690,Q9NY93,P17096,P19338,Q9H6F5,Q99848,Q9H7E9,Q9NSI2,P54132,P46777,Q9Y4C8,P61353,P62263,P36578,P09874,O00566,Q96GA3,Q14692,P42696,Q5BKZ1 43 +nuclear_punctae 0.4992186853156403 4.436580857387591 9.139901295140971e-06 0.0001553669613963 7.768916100870677e-05 89 Q9NPJ6,Q96GM5,P46013,Q8IXT5,Q12834,O60885,P24928,O75150,P98179,P38159,Q9BRK0,O15160,Q9HD42,P09012,P78332,Q15233,Q8IX12,Q66PJ3,P17480,Q13523,Q9NVC6,P08579,Q01844,P23246,O95400,Q9NPA8,Q8WXF1,P54132,Q96PK6,O14802,O00311,O75190,P55769,P67870,P25440,P11142,Q5BKZ1,Q14683 38 +chromatin 0.4253144324360144 3.205154246259725 0.0013499011943549 0.0227021613966084 0.0057370800760085 100 P46013,Q8IXT5,P11387,P51608,Q9Y5B9,Q9Y3B4,P38159,Q92922,Q12824,P09012,P52756,Q9UIG0,Q15233,Q13435,Q71SY5,Q8WUB8,Q8WYA6,Q969G3,Q13523,P98175,Q9NTZ6,P08579,O14497,Q00839,P25490,P23246,Q96T37,P07305,P17096,Q96I25,Q14980,Q9BTD8,Q9NW64,Q9BQ61,Q14807,Q9NRL2,Q14498,P42167,P26583,Q8TAQ2,P49756,P05204,Q9H1E3,P55072,Q15459,Q14683 46 +nucleolus_fc_dfc 0.5725886660915548 3.0823780170059702 0.0020535387578302 0.0343424905450411 0.0069820317766227 26 Q96PK6,Q13428,Q01844,Q8IXT5,P17480,O60832,Q9NPE3,O00311,Q969X6,P55769,Q9NTZ6,P78332,Q15233 13 +membrane 0.4014295607334701 2.995669168881356 0.0027384335721765 0.0455473355118012 0.0077588951211667 90 Q13464,Q16513,Q9UHD8,Q9NZM3,Q96N67,P46939,Q9UNF0,Q15758,Q13740,Q9ULV4,P15311,P09496,O15127,P19022,Q14247,Q9Y5S2,O43795,P84095,Q9UM54,Q13308,Q99961,P04920,O00291,Q9Y6W5,Q15019,P35579,O00159,Q9UKS6,Q9H2G2,P20020,P22059,P67870,Q9UQB8,Q9NVZ3,Q02952 35 +cell_contact 0.5144158399195544 2.9024663829031745 0.0037023689396962 0.061110114431188 0.0089914674249765 34 Q9NVZ3,Q13464,Q13740,Q07157,Q9UDY2,O96013,Q99961,Q9UJU6,Q9NZM3,Q15942,P19022,O43795,Q96N67,Q9UKS6,P22059,Q9UQB8,Q14247,P18206 18 +cytoskeleton 0.4571801285456849 2.34599957457999 0.0189761291294625 0.2779741018326821 0.0358437994667626 34 Q13409,Q13561,Q8WWK9,Q99661,Q7Z460,P27816,Q9UHD8,Q05682,Q13043,P55072,P35580,Q9Y6G9,Q15019,P35579,Q14008,O00139,P12814 17 +centrosome 0.3946398677953489 1.7927376648876092 0.0730148809375148 0.7244268112344814 0.1241252975937752 37 O14745,Q13409,Q13561,Q9UPN4,Q8WWK9,Q99661,Q7Z460,O96013,Q13442,P23258,Q9BV73,O43237,Q9Y6G9,Q14008,P33176 15 +nuclear_membrane 0.3386979736282918 1.1116345395094591 0.2662953156209151 0.9948255766068316 0.3772516971296297 33 P42167,P49792,P12270,Q8NC56,Q9Y5B9,Q9NPA8,P20700,Q9Y2U8,P55735,P02545,P49790,Q5JTV8,P35658,Q8NFH5 14 +focal_adhesions 0.3369533505372182 0.2158748092648997 0.8290853334263157 0.9999999999999094 1.0 7 P18206 1 +big_aggregates 0.213755703892674 0.1038713974671657 0.9172714058119652 1.0 1.0 34 Q8NFH5,Q14247,P35658,Q9NZI8,Q02952 5 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..dfeb125cc11edee90121a0ca6a3833849d1b601f --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", 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b/panther_protein_class/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d7f18d2a00396526bd5691b52d95b8f85eeeb894999f7a2b0dfb38f6b2bfadd7 +size 153452 diff --git a/panther_protein_class/consensus.joblib b/panther_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..4b53cbf613d63b0ef059d459e4dc2380082bcee2 --- /dev/null +++ b/panther_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:99c48c2da3c7bf8fd1f4e2d3a42454a277955e55e1524f17b2076928b5dcfb5a +size 99520 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..87550862407a4d321892cbe2ad2812b7d71411c7 --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,12 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +RNA metabolism protein 42 93 4.401024067645516 1.0774117189082943e-05 31.237864077669904 92.75728155339806 -0.5623355259650072 0.5673116865303599 11.981852106575811 5.389158515320546 0.937994409284748 0.3401234413422416 1.0 0.5122277386999536 0.0029716947576053 0.0029864552398499 1.3631833116415599e-09 +RNA splicing factor 40 85 4.259490991796774 2.048929558085e-05 25.516990291262136 80.2135922330097 -0.4027847736134791 0.5859415472752173 9.732450108601151 5.238766039835511 1.0479507672919537 0.3497485651761058 1.0 1.0 0.0351687642431511 0.0122504382358531 1.02793849599523e-05 +ribosomal protein 56 131 3.3754911149225317 0.0007368407127268 52.657766990291265 120.1504854368932 -1.1188580775071333 0.366830351444047 16.3572632501004 6.355310810063214 1.8172532741960228 0.3740231821116406 1.0 0.0085414395311053 3.3033118724142056e-05 2.7631538038503697e-06 2.9921456447923776e-10 +DNA-binding transcription factor 8 19 2.970603690556684 0.0029721505181066 6.730582524271845 18.24514563106796 -0.5381941976731367 0.541659964372557 3.388692884651944 3.2576423555472855 0.7383308157936146 0.2996598060883814 1.0 0.4447949641299413 0.3260913714049449 0.1678388076683865 0.3606228290403846 +histone 7 10 2.5753446081670317 0.010014025894578 6.609223300970874 9.031553398058252 -1.6306599901637746 0.1679998135987644 2.1722460253840654 0.5227582880559347 1.3516587276133298 0.2649142488697017 1.0 1.0 1.0 0.1003847610205272 0.0004973671187583 +DNA metabolism protein 16 38 2.4926195886680715 0.0126804620905605 12.783980582524272 37.157766990291265 -0.5301091012041882 0.5387930255314917 5.9205447531777216 3.7106332205113977 0.928364799127104 0.3371866575431892 1.0 0.3682511930157578 0.6018020784024207 0.1941365093441881 0.1675071972901493 +zinc finger transcription factor 5 7 2.4358703666901107 0.0148560074804471 3.3470873786407767 7.177184466019417 -0.6346113062721356 0.4577788696212375 2.0735074786963352 2.9213249811658986 0.891486415175454 0.3116593814885879 1.0 0.012648542478749 0.0459506122728715 0.0101719456814394 0.0261400621732643 +actin or actin-binding cytoskeletal protein 12 19 2.370861751039236 0.0177466677425743 7.953883495145631 20.225728155339805 -0.3151113675020994 0.5775443486026427 4.241531765127069 2.185570109330632 0.8318989766705701 0.3072966942476308 1.0 1.0 0.4528388306838392 0.4432698910877191 0.0756252939231378 +transcription cofactor 4 13 2.3454988677376765 0.0190016363042 3.849514563106796 11.368932038834952 -0.1854477393871992 0.5658080079355859 2.4028047440725246 2.0843396256351627 0.8452495936511446 0.2952942603841224 1.0 1.0 0.4688773052385803 0.4679524167182146 0.2007884256395009 +histone modifying enzyme 6 13 2.243967076653309 0.0248345197405559 3.6893203883495143 12.859223300970871 0.0363233460240363 0.5130278596738178 2.7307281514565176 3.475236581824501 1.0011374616004485 0.3161877703975937 1.0 1.0 1.0 0.3833676775949033 0.0465202107555725 +extracellular matrix protein 3 6 2.237586384446669 0.0252480402683925 1.6189320388349515 4.0 -0.1964888416292719 0.5403703942010945 1.139720126283232 1.3108953436265411 0.9839266598074892 0.3194805059415276 1.0 0.1070183553885475 0.2030300441679912 0.0179536348510701 0.09905667817091 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..dc1da7f50c99855b80558451b5440757a8633631 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 162, + "title": "Average number of proteins per term", + "value": 15.067901234567902 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..407854802464fb93d19f9c3a8a275d7d89209223 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..46ebfa64019b957c12f7f2fea947ec65b74b9000 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,52 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +RNA metabolism protein 0.5008428888355064 4.4010240676455155 1.0774117189082943e-05 0.0017438940339685 0.0016596329420489 93 Q8WWM7,Q13283,Q9Y6M1,Q6PKG0,Q9NV06,Q92945,Q9NZI8,Q15233,Q96AE4,Q8IY67,Q5T8P6,P48634,Q14444,Q12906,Q9H6R4,O75683,Q9H814,Q00341,Q9Y520,Q86V81,Q9BVJ6,Q9BTE6,Q01844,P23246,Q96T37,Q14690,Q9NPE3,Q9HAU5,Q8WXF1,Q5T3I0,Q9BY77,P78316,Q86U38,Q96I24,P05455,Q13428,O00566,Q9P2N5,Q969S3,Q9Y3Y2,Q8NC51,Q8NEF9 42 +RNA splicing factor 0.4821076882696212 4.259490991796774 2.048929558085e-05 0.0033137971035439 0.0016596329420489 85 Q8IXT5,Q13573,Q14331,P18583,Q9Y3B4,Q15637,Q01081,Q9H7N4,P09012,Q13243,Q13435,P52272,Q8IX01,Q12972,P62314,Q96PU8,Q9NTZ6,P08579,P41223,P62304,O95400,Q08170,Q9ULR0,P08621,Q96I25,Q9NW64,Q9Y4C8,Q92917,Q9H9Y2,Q96PK6,O43395,Q12849,Q9BW85,Q15287,Q01130,O75494,Q9BWU0,Q05519,P84103,Q15459 40 +ribosomal protein 0.4631308956727165 3.3754911149225313 0.0007368407127268 0.1125580735414689 0.0298420488654369 131 P62913,P83731,Q5T653,Q92665,P26373,P61247,P50914,Q9BYD2,P62917,P84098,Q9NQ50,Q9BRJ2,P62841,Q15050,P52815,Q9Y3D9,Q02878,Q9Y3B7,Q9UHA3,P47914,P46776,P46778,P62753,Q9BYN8,Q13405,Q14137,P82912,P61254,P62424,Q96A35,P62750,Q9Y291,P62273,Q9Y2R9,P62081,P62899,Q9P015,P62857,P39019,P46777,P46779,P61353,Q8IXM3,P46782,P62263,P83881,P36578,P05387,Q96GC5,P55769,Q9BYD3,P82650,P40429,P82673,Q6P1L8,P62847 56 +DNA-binding transcription factor 0.6464741665341621 2.970603690556684 0.0029721505181066 0.3825797279143594 0.060186047991659 19 Q01664,P20290,P17480,Q9NPA8,Q8WXI9,Q86YP4,Q9NXV6,Q15906 8 +histone 0.7262333891110788 2.5753446081670313 0.010014025894578 0.804158490313174 0.0811136097460818 10 P16403,P16104,P10412,P07305,P16402,Q9P0M6,Q92522 7 +DNA metabolism protein 0.4574927014261118 2.4926195886680715 0.0126804620905605 0.8734819563087033 0.0864630400982999 38 Q8WVB6,Q04837,P09874,P25205,P54277,P51608,Q9NRF9,Q9BQ61,P20585,P18887,P33991,Q12824,Q9NYB0,Q15477,Q96QE3,P35251 16 +zinc finger transcription factor 0.7999396938128517 2.4358703666901107 0.0148560074804471 0.911497903465756 0.0962669284732974 7 Q9UBW7,Q9UPT8,Q5SVZ6,Q5VZL5,O94880 5 +actin or actin-binding cytoskeletal protein 0.5624747788348912 2.370861751039236 0.0177466677425743 0.9450194915417136 0.1020187602157034 19 P59998,Q9NR12,Q6WCQ1,P15311,Q15942,Q9UHB6,Q9UKS6,Q9NYL9,O00151,Q16527,Q96HC4,Q9UNF0 12 +transcription cofactor 0.6345806894753563 2.3454988677376765 0.0190016363042 0.9553047014664784 0.1026088360426802 13 Q9HCD5,P51858,Q7Z4V5,Q9Y3E1 4 +histone modifying enzyme 0.6182048826893838 2.2439670766533095 0.0248345197405559 0.9829906492990176 0.1202994859846939 13 Q96T23,Q15910,Q8WUB8,Q92785,Q7LBC6,Q9H7B4 6 +extracellular matrix protein 0.8079090045178331 2.2375863844466695 0.0252480402683925 0.9841201295493855 0.1202994859846939 6 P55081,P11047,P07942 3 +C2H2 zinc finger transcription factor 0.7407199443844605 1.9269634146542085 0.0539841895001551 0.9998753937166872 0.200252447881245 6 O95785,Q7Z3K3,P25490,Q9Y467 4 +nucleic acid metabolism protein 0.7830447601533628 1.8355710071236837 0.0664211283927782 0.9999853962521026 0.2105000511326865 5 Q9Y2W1,Q9NYF8 2 +chromatin/chromatin-binding, or -regulatory protein 0.3514012884543346 1.66841019654374 0.0952343255063508 0.999999909039938 0.2573432113421194 52 Q96ST3,Q9UIF9,Q15014,Q96GM5,Q9NPF5,Q9Y5B9,Q9H0U9,Q92922,Q8IX12,Q8IXM2,O75446,Q969G3,Q9NY61,Q9BV73,Q9UBU8,P05114,P16383,Q92925,Q13111,Q99733,Q86U86,Q8TAQ2,P05204,O75717,Q13112 25 +actin binding motor protein 0.6420566734494453 1.6541913245241793 0.0980886450092421 0.9999999454814296 0.2573432113421194 7 Q9UM54,O00159,O94832,O43795 4 +chaperonin 0.5631394943803343 1.644476010986481 0.1000779155219353 0.9999999618762708 0.2573432113421194 10 P61604 1 +protein-binding activity modulator 0.6571693595982049 1.529038525648705 0.1262548935205636 0.9999999996806032 0.3007837169166369 6 Q9UBC1,Q9UNZ2,P14314 3 +defense/immunity protein 0.8956689844052008 1.51034548705927 0.1309552906537621 0.999999999866702 0.3074602476218762 3 O75179 1 +mRNA capping factor 0.7538893482770163 1.4646601876730982 0.1430136520656941 0.9999999999861398 0.3309744519234636 4 Q8IZD4,Q6P2E9 2 +non-motor microtubule binding protein 0.4064458939968942 1.4478853061203512 0.1476491297440154 0.9999999999942432 0.3368895636412747 24 P46821,Q3KQU3,Q96CW5,Q66K74,Q8WWK9,Q15555,Q9BSJ2,Q9ULW0,Q14008,Q9UN37 10 +microtubule binding motor protein 0.4344907968769316 1.3944243571933037 0.1631894970633081 0.999999999999708 0.3651904502112692 19 P52732,Q13561,Q07866,Q99661,O95239,Q02241,Q9Y496,Q14807,Q86Y91,Q9H0B6,Q96Q89,Q9UJW0,Q8NCM8,O00139,P33176 15 +tight junction 0.8310363836824688 1.389893799337377 0.1645611287989052 0.999999999999776 0.3651904502112692 2 Q07157 1 +general transcription factor 0.3612782282970459 1.3428736003459 0.1793129060756324 0.9999999999999876 0.387315877123366 33 P35269,Q9NPJ6,P23193,O75175,Q71SY5,O14776,Q9BTC0,P29083,Q16625,P13984,Q92576,Q9NVC6,Q15648,P53999,Q9Y5Q8,P32780 16 +mutase 0.6085752767097258 1.2937268016913914 0.1957598042197568 0.9999999999999996 0.4065780549179564 6 Q96HS1 1 +GTPase-activating protein 0.4304451327097945 1.2818981171444055 0.19987838855431 0.9999999999999998 0.4098772018455472 17 Q4KMP7,A1A4S6,Q9H0H5,Q86VI3,Q07960,Q15042,Q8N6T3 7 +phosphatase modulator 0.5301910859212204 1.264674115278973 0.2059881725994088 1.0 0.4154127898870766 8 Q15435,O14974 2 +microtubule or microtubule-binding cytoskeletal protein 0.4500456744650604 1.252821510727249 0.2102706714243227 1.0 0.4154127898870766 14 Q13409,Q14980 2 +non-motor actin binding protein 0.3503418586198801 1.2305462180962548 0.2184926308096795 1.0 0.4213786451329533 33 Q9Y281,Q9ULV4,O75146,P55196,O00291,Q05682,Q9Y6W5,P35611,P35221,P47755,Q14247 11 +chaperone 0.2783442769520153 1.1794473266363787 0.2382200992889012 1.0 0.4435822538482987 80 P13667,Q9Y3C6,Q99543,Q8N183,Q9H2H8,Q00688,Q13427,Q6UX04,P30533,Q13526,P31689,P25685,P06748,Q8WUA2,Q14203,Q96EY1,Q8NBS9,P30101,Q5F1R6,Q8WXX5,Q13356,P30414,O75937 23 +Hsp90 family chaperone 0.6781577495863237 1.1440112456492362 0.2526189732694219 1.0 0.4547141518849595 4 P08238,Q12931,P07900 3 +RNA processing factor 0.3316906817670212 1.074274923174441 0.28269948085481 1.0 0.479015876017607 35 O95104,Q6P6C2,O75152 3 +cytoskeletal protein 0.5081517851634618 0.9637713381250264 0.3351605794527588 1.0 0.5375842957559102 7 Q15019,Q14141 2 +RNA methyltransferase 0.3936663591027398 0.8710068381733982 0.3837504193675531 1.0 0.5903585595550922 14 Q96FX7,Q8WVM0,Q8IY81 3 +homeodomain transcription factor 0.6835722160970166 0.7770735564435628 0.4371153742719622 1.0 0.6618008470285783 2 O94776 1 +kinase inhibitor 0.6936862420733365 0.7389023423822949 0.4599662998849507 1.0 0.6899494498274261 3 Q9NQG5,Q96P16 2 +translation release factor 0.5710793848845993 0.7034450680031483 0.4817784287294144 1.0 0.7031360851726589 4 Q14197 1 +damaged DNA-binding protein 0.6757487404383642 0.6749765573073685 0.4996906590097336 1.0 0.7227668460676505 3 O60934 1 +translational protein 0.6491179713340609 0.6441247016322363 0.5194945735754082 1.0 0.7447621320284613 2 Q12904 1 +intermediate filament binding protein 0.4069824394681128 0.4783825021499928 0.6323779853332989 1.0 0.8547034871282884 7 Q03001,Q15149,O00192,P58107 4 +translation elongation factor 0.3415412066331771 0.4338547287992393 0.6643939361533819 1.0 0.8788930827727769 12 Q8NE71,P29692,Q9NUQ8,Q9UG63 4 +amino acid kinase 0.5722160970231421 0.3789948062627716 0.7046917206616017 1.0 0.8918754589623397 2 P12532 1 +non-receptor serine/threonine protein kinase 0.2250411704975644 0.2249107140790405 0.8220487341902203 1.0 0.9816213978510936 64 Q13464,Q16513,P51956,O00311,P42345,Q2M2I8,Q13523,O96013,Q99640,Q13043,O75116,P11802,Q9Y5S2 13 +integrin 0.5058533707393016 0.1868404782821559 0.8517857086426974 1.0 0.9971679787227898 3 P17301 1 +cadherin 0.3944571958587227 0.1494362344691389 0.8812094217419864 1.0 0.9971679787227898 4 P19022,O60245 2 +ubiquitin-protein ligase 0.2139310639780419 0.1476166672429372 0.8826453006542823 1.0 0.9971679787227898 67 Q12834,O60858,Q8TBC4,Q7Z6Z7,O15344,Q7Z6E9,Q13564,O75592,Q13620,P61088,O95628,P19474,Q99496,Q9NT62,Q9GZZ9,Q5TAQ9,P14373,O43164,Q9UBT2,P22314 20 +translation factor 0.288711012972665 0.094975071850858 0.9243346271799842 1.0 1.0 7 Q53EL6,Q9Y450,P51114,P51116,Q05639,Q06787 6 +basic leucine zipper transcription factor 0.3418527366922723 0.0655032059700145 0.9477733538251488 1.0 1.0 4 Q9NQ48 1 +G-protein modulator 0.2688951805228237 0.0383119015771229 0.9694390016675114 1.0 1.0 6 P11274 1 +exoribonuclease 0.2024861878453007 0.0133011816977097 0.9893875054135142 1.0 1.0 10 Q9GZR2,Q9H0D6,Q9Y2L1,Q5RKV6,Q06265,Q9NQT4,Q15024,Q9NPD3,Q96B26 9 +scaffold/adaptor protein 0.1972707238221354 0.0074871852901479 0.994026146266832 1.0 1.0 97 O60664,Q9UKX7,Q8IZP0,Q8WYP5,Q15398,O60271,Q5SSJ5,O60828,Q14168,Q6SZW1,Q9UQB8,P43487,Q9P2E9,Q9Y5X2,Q8N3R9,Q5BKZ1,Q02952 17 +guanyl-nucleotide exchange factor 0.1804333949458251 0.0008898715396739 0.999289985331103 1.0 1.0 11 Q92888 1 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b2f5522e3a23bb3b90b2a90c88d2f944b582f023 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic helix-loop-helix transcription factor", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "cell junction protein", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin receptor superfamily", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase inhibitor", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAK1", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABR", "ACAA1", "ACAA2", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "ALYREF", "AMFR", "AMPD2", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANKHD1", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APEH", "APLP2", "APOBEC3C", "APOC1", "APOL2", "APP", "APRT", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF7", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6", "ARL6IP5", "ARPC3", "ARPC4", "ARRB2", "ARVCF", "AS3MT", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATL2", "ATL3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAP18", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCKDK", "BCLAF1", "BCR", "BECN1", "BLM", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CABIN1", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX8", "CCAR1", "CCAR2", "CCDC12", "CCDC94", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2BP2", "CD320", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC7", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CEP170", "CEP250", "CEPT1", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNP", "COA3", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ3", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWC27", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCAKD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERL1", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "ENY2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERH", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FIGNL1", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GID8", "GINS2", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGCR", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTATSF1", "HUWE1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "ISOC1", "ISOC2", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLC2", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTN1", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MBOAT7", "MCCC1", "MCCC2", "MCFD2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "MFAP1", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIPEP", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTIF2", "MTOR", "MTPAP", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA50", "NADSYN1", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCEH1", "NCK1", "NCKIPSD", "NCOA5", "ND1", "ND5", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK3", "NENF", "NFKBIL1", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAFAH1B3", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PARG", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDXP", "PDZD11", "PDZD8", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUDP", "PUF60", "PURA", "PUS1", "PWP1", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBM7", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIOK2", "RIPK1", "RNASEH2A", "RNF14", "RNF2", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SACM1L", "SAE1", "SALL2", "SAMHD1", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP29", "SNAP47", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPAST", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STK4", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAP1", "TAPBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TBPL1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TERF2IP", "TES", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM259", "TMEM38B", "TMEM87A", "TMOD1", "TMOD3", "TMPO", "TMX2", "TMX3", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRAP1", "TRAPPC4", "TRIM13", "TRIM21", "TRIM24", "TRIM26", "TRIM27", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBR4", "UBR5", "UBR7", 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sha256:0ea84761cc680e30510acf37853d67e5830df4fbce08f6c875981a44b5603c17 +size 140811 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..54defa198b9a4a1a3e2aacb04ef533bcad00ef3c --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dce1df6d0c32b77ad876b7a450b48c5826f38b4effbe850cc181351d5ea4720d +size 506091 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..504b9af53e852a8f4847e7216e93ee4ee8a06bac --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,20 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Ribosomal protein 46 113 4.104208998045737 4.0570058050803937e-05 44.13834951456311 104.5509708737864 -0.839027584662447 0.4092064110759666 15.168720536445749 4.970282954685487 1.664286665300548 0.3711973750179467 1.0 0.029947979425984 7.867929941041457e-06 6.939675784139898e-06 2.128333592725539e-09 +Nucleic acid binding 146 365 3.870060016739668 0.0001088085634648 113.94417475728156 345.7718446601942 -0.9848012837682238 0.468469235111674 35.78691372865069 18.45162616811088 1.4009825801667193 0.3527437669119357 1.0 0.1816679931454843 2.538076685611633e-05 3.0609266619834447e-10 1.6239575958204054e-17 +DNA binding protein 29 61 3.8498706039122186 0.000118180242056 20.478155339805824 58.519417475728154 -1.266578992690203 0.3737299551302104 8.302357162957183 4.802114385693747 1.3218667098570367 0.3698692290617101 1.0 0.5218629256102782 0.7722229142029041 0.0110451649289294 0.0009234153495659 +mRNA processing factor 32 80 3.33513360764393 0.0008525842472779 25.347087378640776 75.25485436893204 -0.2985441958276097 0.5602779604890878 10.316515944124484 3.6776154061944775 1.2913421409729118 0.3651678095317845 1.0 1.0 0.0195932975716513 0.0042069843872108 4.477184029965852e-05 +mRNA splicing factor 28 63 3.262766913492611 0.0011033022231232 20.18446601941747 60.25 -0.0534479997211008 0.543839505368344 8.174667919166573 3.2318387263906065 1.3503022593676848 0.3639653466937346 1.0 1.0 0.046481015474091 0.015192442240151 3.68116267568313e-05 +Chromatin/chromatin-binding protein 16 23 2.874611815857763 0.0040452450503132 8.12864077669903 21.854368932038835 -0.6070278188676178 0.496621256709513 4.184513183118974 2.682766891473473 0.8534743600474233 0.3128500615356763 1.0 1.0 1.0 0.0534645551123919 0.06212243803085 +Kinase modulator 9 17 2.693281221610772 0.0070752562951994 5.737864077669903 16.00242718446602 -0.3720481483052619 0.5632583440828297 3.1204342648007497 3.0936034746376486 0.7900822750391858 0.2979709409596938 1.0 0.312708212996757 0.5285075461630524 0.0385044935648457 0.1651336338173519 +Histone 8 11 2.6400385714807406 0.008289659193946 7.216019417475728 10.975728155339803 -1.5979454556388497 0.182832993896989 2.277887728681405 0.5524817827541809 1.3263740895704466 0.2762788415361712 1.0 1.0 1.0 0.1003847610205272 0.0004973671187583 +Actin family cytoskeletal protein 25 55 2.6379494412473425 0.0083409016368307 20.116504854368937 51.213592233009706 -0.9384190662504722 0.451609577748554 7.9751446051640595 4.741165489904156 1.1825561513640697 0.3714840113795736 1.0 1.0 0.7017079055797242 0.3507507559444638 0.0355762548676044 +RNA binding protein 114 278 2.370370461115683 0.0177702697734367 87.39805825242719 263.81067961165047 -0.7141181185949859 0.5274837744320973 28.928381537264386 11.410822767756809 1.087336744382709 0.3484948637163224 1.0 0.1093348745823862 1.0816738567068842e-07 2.1457765322957708e-09 9.367549065050619e-17 +STE group 4 7 2.2865854157771555 0.0222200333028963 3.2645631067961167 7.145631067961165 -0.1227897712510759 0.57219799430361 2.0421306580770753 1.9873765064658129 0.863134294577686 0.3063317334502429 1.0 1.0 1.0 1.0 0.2822516950414785 +Microtubule family cytoskeletal protein 27 52 2.286065447054687 0.0222504300429162 13.95388349514563 44.689320388349515 -0.1362213656804705 0.619784536589291 6.314208777929424 5.456410011879574 0.9169883864186168 0.3228121160578749 1.0 0.4251307382490726 0.3007633023667535 0.7650902497478976 0.8022604212789366 +Epigenetic regulator 11 29 2.233158398407024 0.0255385006507469 8.553398058252426 28.99514563106796 -0.1286088691273567 0.5473177327930165 5.110389484785854 3.4310087576828545 1.01171455712642 0.3313158396227147 1.0 0.3228460923172884 0.181453052630302 0.0443223277805319 0.0380095176885234 +Reader 5 13 2.2314142694336745 0.0256537005148096 5.70873786407767 13.12621359223301 -0.4677715909366409 0.5292669377395962 3.1326066814404174 1.793621988567687 0.8806250617432968 0.3150242727325907 1.0 0.1373006943976843 0.2562935091164666 0.1669228189673315 0.0560616912320164 +Kinase inhibitor 3 6 2.142316132203346 0.032168051549005 2.8567961165048543 5.689320388349515 -0.6530006073943508 0.4436840193533882 1.4569476762214402 1.3954094378687043 0.8365386470228158 0.2887982225450033 1.0 0.0711332726649859 0.1375212864755611 0.0053269286919759 0.0049531384619904 +Cellular structure 55 118 2.125706224470881 0.0335277283361963 35.286407766990294 106.15533980582524 -0.6469900848388579 0.5081494044693075 12.944823522470315 10.34291397744012 1.1134225716446935 0.352675070732342 1.0 0.7273993071547002 0.473952816124696 0.6214647918213958 0.2049156491005032 +Non-motor actin binding protein 13 30 2.1234725540483184 0.033714273016332 11.79611650485437 27.01456310679612 -0.8474974264878427 0.4498045512444004 5.113961896386084 2.8514655665263597 1.0629229201374764 0.3457936810592598 1.0 1.0 1.0 0.3745777826514135 0.1146874089692008 +STE20 family 4 6 2.1066289933038966 0.0351497515270673 2.320388349514563 5.179611650485437 0.0295512247407655 0.5953049690173855 1.5198594226831097 1.528617576061733 0.8336986630252057 0.3017728670085233 1.0 1.0 1.0 1.0 0.1093101132411038 +Ribonucleoprotein 7 18 2.0158117630543657 0.0438196630537857 7.019417475728155 15.565533980582524 -0.8660159276547141 0.4164784725653225 2.9934575343872907 1.23385749846375 0.8139787780336539 0.3127058360643692 1.0 1.0 0.2030300441679912 0.1082353444632946 0.09905667817091 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..dab7187b7afe713c4942c5c41be891ba446ef62a --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 2243, + "title": "Average number of proteins per term", + "value": 3.142666072224699 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..dd21e3e5b47f9823830b5957e4562d88c0cb531a --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4115b92a25a31e298157a2bfdbe3f2adebfcb12b --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,67 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Ribosomal protein 0.4985779749446343 4.104208998045737 4.0570058050803937e-05 0.0869827329805666 0.027087246533065 113 Q8IXT5,P62913,P83731,Q5T653,P26373,P50914,Q9BYD2,P62917,P84098,P62841,Q15050,P52815,Q02878,Q9Y3B7,Q9UHA3,Q9NTZ6,P47914,P46776,P46778,P62753,Q13405,Q14137,P82912,P61254,P62424,Q9NPE3,Q96A35,P62750,P78316,P62081,P62899,P62857,P46777,P39019,P46779,P61353,Q8IXM3,P46782,P62263,P83881,Q12849,Q96GC5,P55769,P40429,P82673,Q6P1L8 46 +Nucleic acid binding 0.4608212661509083 3.870060016739668 0.0001088085634648 0.2165679025383408 0.027087246533065 365 Q8IXT5,Q6PKG0,P38159,P83731,P20585,P49790,Q15233,P62917,P84098,P52272,P62841,Q12906,P52815,Q96PU8,Q86V81,P47914,P08579,O95104,P23246,Q08170,P62424,Q9NPE3,P62750,Q9BY77,P78316,P62081,Q13111,P62899,Q9H9Y2,Q8IVW6,Q8IXM3,O43395,Q01130,O75494,P05204,P40429,Q6P1L8,Q9Y5Q8,Q9BTC0,Q8WWM7,Q15014,O75152,P13984,P98179,Q96E39,Q86YP4,Q15637,Q5T653,P62805,O75446,P16402,O60934,Q8WXI9,Q15050,Q9H814,Q9UHA3,Q9NTZ6,P35658,P46778,P05114,P82912,P61254,P08621,P19338,P16383,P49750,P17096,Q92522,P46779,P61353,Q9C0J8,Q92917,O94776,P05455,P46782,P62263,P26583,P83881,O00566,Q15287,Q96GC5,Q969S3,Q9Y3Y2,P82673,Q05519,Q15459,Q13283,Q14331,P62913,P09012,P26373,P50914,Q13243,Q8IY67,O75683,Q9H6R4,P62314,Q9NXV6,O95628,Q9BTE6,P35269,P46776,Q01844,P16403,P16104,P10412,P07305,O95400,Q13405,Q14137,Q14690,Q96A35,Q8WXF1,Q15056,Q9Y2R9,P62857,P39019,Q86U38,O43432,P54727,Q96PK6,Q04837,Q12849,Q9P2N5,P55769,Q92576,Q8NC51,Q9UN86,O75717,P62847,P84103,Q01081,O15347,Q9NV06,Q9BYD2,Q5T8P6,Q02878,Q9Y3B7,P62753,P23588,P46777,Q9Y4C8,Q13416,Q9P0M6,P33240,Q13112 146 +DNA binding protein 0.5147584771399049 3.8498706039122186 0.000118180242056 0.2328661238527097 0.027087246533065 61 Q15014,Q86YP4,O15347,P20585,P62805,O75446,P16402,O60934,Q8WXI9,Q9NXV6,P16403,P16104,P10412,P07305,O95400,P05114,P17096,Q13111,Q92522,O94776,P54727,Q04837,P26583,Q13416,P05204,Q9P0M6,O75717,Q13112,Q9Y5Q8 29 +mRNA processing factor 0.4127304840451032 3.33513360764393 0.0008525842472779 0.8523871260209133 0.027087246533065 80 P98179,P38159,Q96E39,Q15637,P09012,Q15233,Q13243,Q8IY67,Q8IX01,Q12906,P62314,Q96PU8,P08579,P62304,Q01844,O95104,P23246,Q08170,P08621,Q96I25,P19338,Q8WXF1,Q9Y4C8,Q9C0J8,Q96PK6,O43395,Q15287,Q01130,O75494,P33240,P84103,Q15459 32 +mRNA splicing factor 0.4612951248562009 3.262766913492611 0.0011033022231232 0.915927273767508 0.027087246533065 63 P98179,Q96E39,P38159,Q15637,P09012,Q15233,Q13243,Q8IY67,Q8IX01,P62314,Q96PU8,P08579,P62304,Q01844,P23246,Q08170,P08621,P19338,Q8WXF1,Q9Y4C8,Q96PK6,O43395,Q15287,Q01130,O75494,P33240,P84103,Q15459 28 +Chromatin/chromatin-binding protein 0.5872512323417394 2.874611815857763 0.0040452450503132 0.9998874245084974 0.0294930614423235 23 Q15014,Q96GM5,P05114,O75446,O95400,Q92925,P26583,Q8WXI9,P05204,Q86YP4,O15347,Q9UBU8,Q13111,Q9UQR0,Q7KZ85,Q13112 16 +Kinase modulator 0.6264773522590428 2.693281221610772 0.0070752562951994 0.9999998788465052 0.0359045245930596 17 Q9UBW7,Q9NQG5,Q5VZL5,Q5SVZ6,O60271,Q9BV73,Q15942,Q86VS8,Q96ED9 9 +Histone 0.7223535477442411 2.6400385714807406 0.008289659193946 0.9999999922160498 0.0389375697650003 11 P16403,P16104,P10412,P07305,P16402,Q9P0M6,Q92522,P62805 8 +Actin family cytoskeletal protein 0.4257197474492963 2.6379494412473425 0.0083409016368307 0.9999999930678958 0.0389375697650003 55 P35611,P35221,O00151,Q96HC4,P26038,Q9UNF0,Q9ULV4,O75146,P15311,Q9UJU6,Q9H981,Q14247,O94832,O43795,P59998,Q9UM54,O00291,Q9Y6W5,Q9NYL9,Q16527,Q9NR12,P55196,Q9UKS6,P47755,O00159 25 +RNA binding protein 0.4365293806670134 2.370370461115683 0.0177702697734367 1.0 0.057934178927062 278 Q8IXT5,Q6PKG0,P38159,P83731,P49790,Q15233,P62917,P84098,P52272,P62841,Q12906,P52815,Q96PU8,Q86V81,P47914,P08579,O95104,P23246,Q08170,P62424,Q9NPE3,P62750,Q9BY77,P78316,P62081,P62899,Q9H9Y2,Q8IXM3,O43395,Q01130,O75494,P40429,Q6P1L8,Q8WWM7,P98179,Q96E39,Q15637,Q5T653,Q15050,Q9H814,Q9UHA3,Q9NTZ6,P35658,P46778,P82912,P61254,P08621,P19338,P46779,P61353,Q9C0J8,P05455,P46782,P62263,P83881,O00566,Q15287,Q96GC5,Q969S3,Q9Y3Y2,P82673,Q05519,Q15459,Q13283,Q14331,P62913,P09012,P26373,P50914,Q13243,Q8IY67,Q9H6R4,P62314,Q9BTE6,P46776,Q01844,Q13405,Q14137,Q96A35,Q8WXF1,Q15056,Q9Y2R9,P62857,P39019,Q86U38,O43432,Q96PK6,Q12849,Q9P2N5,P55769,Q9UN86,Q8NC51,P62847,P84103,Q01081,Q9NV06,P20042,Q9BYD2,Q8IX01,Q5T8P6,Q02878,Q9Y3B7,P61011,P62304,P62753,P23588,Q96I25,Q9NRX2,Q07666,P46777,P09132,Q9Y4C8,Q53EL6,P33240 114 +STE group 0.7688613156964714 2.2865854157771555 0.0222200333028963 1.0 0.0659282887533173 7 O95747,Q9H2G2,Q13043,O96013 4 +Microtubule family cytoskeletal protein 0.4004269940087533 2.286065447054687 0.0222504300429162 1.0 0.0659282887533173 52 P46821,Q3KQU3,Q99661,Q9BVA1,O75449,Q96Q89,Q9UN37,O00139,Q8WVJ2,P33176,Q13561,Q66K74,Q02241,Q9Y266,Q15555,Q9BSJ2,Q14008,Q8IVD9,Q13409,Q96CW5,Q14807,Q9ULW0,Q9Y6G9,Q9Y496,O43237,Q86Y91,P23258 27 +Epigenetic regulator 0.4587486773777099 2.2331583984070233 0.0255385006507469 1.0 0.0716931876841368 29 Q15910,O60885,P26358,P51608,Q15059,Q96EB6,Q13185,Q7LBC6,P25440,Q9H7B4,Q96L73 11 +Reader 0.6161914919878058 2.2314142694336745 0.0256537005148096 1.0 0.0718418614057255 13 O60885,P51608,Q15059,Q13185,P25440 5 +Kinase inhibitor 0.7870851375543844 2.142316132203346 0.032168051549005 1.0 0.0831255064797445 6 Q9UBW7,Q5SVZ6,Q5VZL5 3 +Cellular structure 0.3729013725436081 2.125706224470881 0.0335277283361963 1.0 0.0844974097281891 118 P46821,Q3KQU3,Q99661,Q9BVA1,P35611,P35221,Q96Q89,O00151,Q96HC4,Q9UN37,O00192,O00139,Q9UNF0,P26038,P33176,Q13561,P35241,Q66K74,Q02241,Q9ULV4,O75146,Q9UJU6,P15311,Q15555,Q9H981,Q9BSJ2,Q14008,P67936,O94832,O43795,Q14247,Q13409,P59998,Q8IVD9,Q96CW5,Q7Z460,Q9UM54,O00291,Q14807,Q9Y6W5,Q9NYL9,Q16527,Q9ULW0,Q9Y6G9,P58107,Q15149,Q9NR12,P55196,Q9Y496,Q9UKS6,O43237,Q86Y91,P47755,O00159,P23258 55 +Non-motor actin binding protein 0.4451173728404448 2.1234725540483184 0.033714273016332 1.0 0.0847770340533998 30 Q9NR12,Q9ULV4,O75146,P55196,O00291,Q9Y6W5,P35611,P35221,O00151,Q9NYL9,P47755,Q96HC4,Q14247 13 +STE20 family 0.7793358492701168 2.1066289933038966 0.0351497515270673 1.0 0.0867688095485403 6 O95747,Q9H2G2,Q13043,O96013 4 +Ribonucleoprotein 0.5227018216499584 2.0158117630543657 0.0438196630537857 1.0 0.0999847461371068 18 Q9H9Y2,P05455,P52272,O00566,Q6PKG0,Q14331,Q01081 7 +C2H2 zinc finger transcription factor 0.7407199443844605 1.9269634146542085 0.0539841895001551 1.0 0.1139960063095724 6 O95785,Q7Z3K3,P25490,Q9Y467 4 +Zinc finger transcription factor 0.5835217784834072 1.8336695443484723 0.0667030621038913 1.0 0.1324026268132993 11 Q7Z3K3,Q9Y467,Q9H582,O95785,O94880,P41223,P25490 7 +Microtubule binding motor protein 0.5299665062055162 1.798154746038206 0.072152488661189 1.0 0.1391556595589398 14 Q13561,Q99661,Q02241,Q9Y496,Q14807,Q86Y91,Q96Q89,O00139,P33176 9 +Cell-cell junction 0.8303916161059024 1.7857623955751891 0.074137737805864 1.0 0.1415242092753643 4 Q07157,Q9UDY2,Q5EBL8 3 +Growth factor 0.6978491029491867 1.724174148090659 0.084676409588686 1.0 0.1558073721964092 6 P51858,O75475,Q7Z4V5,Q9Y3E1 4 +Bromodomain 0.6438537390353103 1.6633823672457977 0.0962359204228966 1.0 0.170503293450677 7 Q15059,P25440 2 +Actin binding motor protein 0.6420566734494453 1.6541913245241793 0.0980886450092421 1.0 0.1723542187330317 7 Q9UM54,O00159,O94832,O43795 4 +Chaperonin 0.5631394943803343 1.644476010986481 0.1000779155219353 1.0 0.1747412618403003 10 P61604 1 +Nuclease 0.374690694323696 1.6443296707245825 0.1001081237025349 1.0 0.1747412618403003 40 Q7Z6E9,P48634,Q9UHB6,Q9Y520,Q9BVJ6,P39748 6 +Non-motor microtubule binding protein 0.4380756286320875 1.5248270099189052 0.1273022511054917 1.0 0.207967188076925 21 P46821,Q3KQU3,Q66K74,Q15555,Q9BSJ2,Q9ULW0,Q14008,Q9UN37 8 +G-protein modulator 0.3701240884551544 1.5019854603562195 0.1331008638597008 1.0 0.2145378864989648 36 Q8IZP0,A1A4S6,Q6WCQ1,P11274,Q9H223,Q9H0H5,Q9H4M9,Q86VI3,Q96D71,Q9NZM3,Q15437,Q96N67,P46940,Q12979,P43487 15 +KRAB box transcription factor 0.7249725608873516 1.3422193272475622 0.1795248916026999 1.0 0.2649173235952999 4 O95785,Q7Z3K3 2 +Tight junction 0.8301626688723451 1.2555165732455436 0.2092912955471373 1.0 0.2967385435601953 3 Q07157,Q9UDY2 2 +Signaling 0.4025483522082132 1.234329754142243 0.2170800529614525 1.0 0.3042166017203523 21 Q8WUJ1,O75475,Q9Y3E1,Q13123,Q7Z4V5,Q5JRA6,Q99627,P51858 8 +ROCK subfamily 0.7907938257993665 1.2191186945191883 0.2227991453709452 1.0 0.30905286522389 2 Q13464 1 +Transcription factor 0.3098667858928454 1.1523962773279566 0.2491582700384293 1.0 0.3328540796284676 55 Q9Y5B9,Q13573,Q9UHR5,Q7Z3K3,O75175,Q71SY5,Q9Y2W1,Q8IZD4,P41223,Q13503,P25490,O14776,Q9Y467,O95785,Q9NYF8,P32780,P17544,Q8WU90,Q9H582,O60828,O94880 21 +Hsp90 family chaperone 0.6781577495863237 1.1440112456492362 0.2526189732694219 1.0 0.3358769158525865 4 P08238,Q12931,P07900 3 +DMPK family 0.7910118555279829 1.1039936073100955 0.2695959107716308 1.0 0.3521861548402841 3 Q13464,Q9Y5S2 2 +Adenylate kinase family 0.7583262734098687 0.9788951799166784 0.3276317740519778 1.0 0.4022321123144972 3 Q9UIJ7 1 +Nucleotide kinase 0.6298234608273805 0.9414817280482268 0.3464580485904907 1.0 0.4175741015521067 4 Q9UIJ7 1 +Chromodomain 0.7203786297955099 0.8364496467220467 0.4029019927564139 1.0 0.4631555886306105 3 Q13185 1 +SLC12 family of cation-coupled chloride transporters 0.6857772877618735 0.7857941378764092 0.4319881014784623 1.0 0.4856888780031033 2 P55011 1 +SET domain 0.5823150364472017 0.747924615799691 0.4545056288967295 1.0 0.5017008492201596 4 Q96L73 1 +Protein methyltransferase 0.423632682947858 0.7460473716041948 0.455638799325188 1.0 0.5027042926150501 9 Q15910,Q96L73 2 +Methyl-lysine/arginine binding protein 0.5141921956505969 0.6435587412294975 0.519861612048673 1.0 0.5510631360232389 5 Q13185 1 +Antibacterial response protein 0.6466372657111273 0.6348239794713532 0.525543222021148 1.0 0.555510578224993 2 Q9NUQ3 1 +Other group 0.333467417807737 0.6295049497063843 0.5290185292844098 1.0 0.5581319666909367 19 P51956,Q2M2I8 2 +Writer 0.3878593587658691 0.615582084636855 0.5381703783544913 1.0 0.5645513034446878 10 Q15910,Q96L73 2 +ERK subfamily 0.6267916207276647 0.5619672223105097 0.5741383516303586 1.0 0.591816324773389 2 P27361 1 +Reductase 0.3213143473898117 0.5257448288408999 0.5990655121274435 1.0 0.6166608277658815 18 P00374 1 +Translation elongation factor 0.5176453528436938 0.5022454648685373 0.6154948653785881 1.0 0.6329917391307534 4 P29692,Q53EL6 2 +Intermediate filament 0.4069824394681128 0.4783825021499928 0.6323779853332989 1.0 0.6497589652325193 7 Q03001,Q15149,O00192,P58107 4 +Intermediate filament binding protein 0.4069824394681128 0.4783825021499928 0.6323779853332989 1.0 0.6497589652325193 7 Q03001,Q15149,O00192,P58107 4 +Protein kinase 0.2321904646318307 0.4779091566221365 0.6327148639062421 1.0 0.6498074357791671 80 Q13464,Q16513,P51956,O00311,Q13308,Q2M2I8,Q13523,P42345,O96013,Q99640,Q13043,Q9H2G2,O95747,P67870,O75116,P11802,Q9Y5S2 17 +Eraser 0.427823718297497 0.4595495100007593 0.6458396069694161 1.0 0.662983175483936 6 Q7LBC6 1 +Dehydratase 0.5975123877914679 0.4182035264121138 0.6757983177065481 1.0 0.6931027099294866 3 P61457 1 +Protease inhibitor 0.3153253972549762 0.3948883295572843 0.6929253032032663 1.0 0.7096947283492814 14 P11047,P07942 2 +DNA-directed RNA polymerase 0.2925068516437028 0.3273538328657432 0.7434002804988904 1.0 0.7603496712991388 15 O14802 1 +AGC group 0.3090116041301174 0.2814384726005982 0.7783741132103419 1.0 0.7939486748207353 12 Q13464,Q9Y5S2 2 +P-type ATPases 0.3557873051490973 0.2774274733471427 0.7814518885288937 1.0 0.7967257208955948 7 P05026 1 +CK2 family 0.5395877962203124 0.2611905253193988 0.7939455842947281 1.0 0.808361300759453 3 P67870 1 +Acetyltransferase 0.2575503262681131 0.258869587730477 0.795735863986673 1.0 0.8098164895290869 24 P24752,Q96T23,P55084,Q8WUB8,Q96N66,Q9NR45,Q92785,P36957 8 +Guanyl-nucleotide exchange factor 0.343275301674405 0.1748304605309556 0.8612128528966734 1.0 0.8728876769305189 6 Q96N67,P11274 2 +Enzyme modulator 0.2540288975204187 0.1655916269523118 0.8684783370435121 1.0 0.8798540695522121 138 Q9UBW7,Q9NQG5,Q8IZP0,A1A4S6,Q12834,Q9Y3E7,Q9H0H5,O00233,O60271,Q9NZM3,Q15437,Q96N67,P07942,Q6WCQ1,Q14141,Q15942,Q9BV73,Q16543,P50454,O14737,P43487,Q86VS8,P11274,P84095,Q9H4M9,Q86VI3,Q5T3I0,P11047,P55036,Q15019,Q5TAQ9,Q5SVZ6,Q5VZL5,Q96ED9 34 +Transcription cofactor 0.1973627972581118 0.0268137759219257 0.9786082655722496 1.0 0.9828619287115102 16 Q13363,Q9Y5B9,Q04726,Q8IZD4,Q7KZF4,O60828,Q99417,P56545,Q15650 9 +Other small molecule kinase 0.2556686674397427 0.0122092966165848 0.9902586327512406 1.0 0.9915848719915324 5 P00558,O00764 2 +Nucleotidyltransferase 0.1802360902844481 0.0066291928085668 0.994710708148198 1.0 0.9955984463973264 36 P49642,O14802,P24928,P54098,O60942,O15160,Q9H3H1,P31153,Q15906 9 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1e96870763294c9612217c86993d42c01cd6c8e1 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome non-ATPase regulatory subunit 9", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S24, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L41, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-aminobutyrate aminotransferase, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-methylcytosine rRNA methyltransferase NSUN4", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMP deaminase 2", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-1A", "AP-1 complex subunit sigma-2", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AP-4 complex subunit mu-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP synthase-coupling factor 6, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 6, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Abl interactor 1", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Actin-related protein 6", "Actin-related protein 8", "Activating signal cointegrator 1", "Active breakpoint cluster region-related protein", "Acyl-CoA dehydrogenase family member 10", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase family 16 member A1", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-parvin", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-beta A4 protein", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Ap2-associated protein kinase 1", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Arsenite methyltransferase", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atlastin-3", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase a", "Aurora kinase b", "Autophagy protein 5", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BTB/POZ domain-containing protein KCTD21", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Basic leucine zipper transcription factor", "Bcl-2 homologous antagonist/killer", "Bcl-2-associated transcription factor 1", "Beclin-1", "Beta-1,4-galactosyltransferase 1", "Beta-1,4-galactosyltransferase 3", "Beta-arrestin-2", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breakpoint cluster region protein", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 3", "CCR4-NOT transcription complex subunit 4", "CCR4-NOT transcription complex subunit 7", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDC7 family", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcineurin-binding protein cabin-1", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding mitochondrial carrier protein SCaMC-2", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calpain-5", "Calponin-3", "Calreticulin", "Calsyntenin-3", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Catechol O-methyltransferase", "Catechol O-methyltransferase domain-containing protein 1", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle 7-related protein kinase", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere-associated protein E", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Centrosome-associated protein CEP250", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Chloride transport protein 6", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Choline/ethanolaminephosphotransferase 1", "Chondroitin sulfate glucuronyltransferase", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-6/CLCN6 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coronin-7", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclic AMP-dependent transcription factor ATF-7", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 16", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 1", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytokine receptor", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DCK/DGK family", "DDB1- and CUL4-associated factor 13", "DDB1- and CUL4-associated factor 8", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA dC->dU-editing enzyme APOBEC-3C", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA polymerase subunit gamma-1", "DNA primase small subunit", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase III subunit RPC5", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(14)-sterol reductase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidine kinase", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-3", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D1", "EF-hand domain-containing protein D2", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "ERO1-like protein beta", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelial protein C receptor", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethanolamine kinase 1", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2 subunit 3", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exostosin-2", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Fanconi anemia group J protein", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Fidgetin-like protein 1", "Flap endonuclease 1", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "GA-binding protein alpha chain", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GDP-fucose protein O-fucosyltransferase 2", "GDP-mannose 4,6 dehydratase", "GEK subfamily", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GPN-loop GTPase 1", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "Gap junction-forming innexin (innexin) family", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General transcription factor IIH subunit 1", "General transcription factor IIH subunit 4", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Geranylgeranyl transferase type-2 subunit beta", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycolipid transfer protein", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein G(o) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Hepatoma-derived growth factor-related protein 3", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone deacetylase complex subunit SAP30", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EZH2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase NSD3", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Huntingtin-interacting protein 1-related protein", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin receptor superfamily", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Katanin p60 ATPase-containing subunit A1", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large neutral amino acids transporter small subunit 1", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Leukocyte elastase inhibitor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosomal-associated transmembrane protein 4A", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 5", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MARK subfamily", "MAST family", "MCU family", "MFS-type transporter SLC18B1", "MHC class II regulatory factor RFX1", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MST subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Mediator of RNA polymerase II transcription subunit 25", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membralin", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metal-response element-binding transcription factor 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7B", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial coenzyme A transporter SLC25A42", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial import inner membrane translocase subunit Tim10 B", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase 7", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Multiple coagulation factor deficiency protein 2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosamine-6-sulfatase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 16, NatA auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "N-terminal kinase-like protein", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADH-ubiquinone oxidoreductase chain 5", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurolysin, mitochondrial", "Neuronal-specific septin-3", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PAX3- and PAX7-binding protein 1", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PDZ domain-containing protein 11", "PDZ domain-containing protein GIPC1", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 14", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PITSLRE subfamily", "PKA family", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pannexin-1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal carnitine O-octanoyltransferase", "Peroxisomal leader peptide-processing protease", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylated adapter RNA export protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polypeptide N-acetylgalactosaminyltransferase 4", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presenilins-associated rhomboid-like protein, mitochondrial", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein FRG1", "Protein Hook homolog 1", "Protein Hook homolog 2", "Protein Hook homolog 3", "Protein LSM14 homolog B", "Protein Mpv17", "Protein NDRG3", "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SEC13 homolog", "Protein SET", "Protein SYS1 homolog", "Protein Wiz", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c delta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxal phosphate phosphatase", "Pyridoxine kinase family", "Pyridoxine-5'-phosphate oxidase", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIO family", "RIO2 subfamily", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein 7", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-2", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rab5 GDP/GTP exchange factor", "Rac GTPase-activating protein 1", "Rac-alpha serine/threonine-protein kinase", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras GTPase-activating-like protein IQGAP3", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 2", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho GTPase-activating protein 10", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Riboflavin kinase", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribonucleoside-diphosphate reductase subunit M2 B", "Ribose-phosphate pyrophosphokinase 1", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SCY1 family", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC18 family of vesicular amine transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sal-like protein 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Segment polarity protein dishevelled homolog DVL-2", "Selenide, water dikinase 1", "Selenocysteine lyase", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 2", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase greatwall", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek3", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase rio2", "Serine/threonine-protein kinase smg1", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "Serpin B6", "Serpin H1", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent HCO3- transporters", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 7", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 25 member 40", "Solute carrier family 25 member 44", "Solute carrier family 35 member F2", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spastin", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Sphingosine kinase 2", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 29", "Synaptosomal-associated protein 47", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 2", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "T-complex protein 11-like protein 1", "TAIRE subfamily", "TAK1 subfamily", "TATA box-binding protein-like protein 1", "TATA-binding protein-associated factor 2N", "TATA-binding transcription factor", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "TTK family", "Tapasin", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Tmem38 family", "Torsin-1A", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Trans-Golgi network integral membrane protein 2", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 10", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transcriptional repressor protein YY1", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 115", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-2", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin gamma-1 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm5", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "U6 snRNA-associated Sm-like protein LSm8", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucuronic acid decarboxylase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "UbiA prenyltransferase domain-containing protein 1", "Ubiquinone biosynthesis O-methyltransferase, mitochondrial", "Ubiquitin carboxyl-terminal hydrolase 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 22", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 38", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VIP36-like protein", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuolar protein sorting-associated protein 72 homolog", "Vacuole membrane protein 1", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 34", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Werner syndrome ATP-dependent helicase", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCHC domain-containing protein 8", "Zinc finger HIT domain-containing protein 2", "Zinc finger MYM-type protein 1", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein 644", "Zinc finger protein ubi-d4", "Zinc finger protein-like 1", "Zinc finger transcription factor", "Zinc transporter 7", "Zinc transporter ZIP10", "Zinc transporter ZIP11", "Zinc transporter ZIP14", "Zyxin", "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial", "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-capping enzyme", "mRNA-decapping enzyme 1A", "mRNA-decapping enzyme 1B", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA dimethylallyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AAK1", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ABI1", "ABR", "ACAA1", "ACAA2", "ACAD10", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "ALYREF", "AMPD2", "ANAPC1", "ANGEL1", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APEH", "APLP2", "APOBEC3C", "APOL2", "APP", "ARCN1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP10", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC3", "ARPC4", "ARRB2", "ARVCF", "AS3MT", "ASAH1", "ASNA1", "ASNS", "ATAD2", "ATAD3A", "ATAD3B", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GALT1", "B4GALT3", "BAG6", "BAIAP2", "BAK1", "BCAP31", "BCAS2", "BCAT2", "BCKDK", "BCLAF1", "BCR", "BECN1", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CABIN1", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC20", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC7", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CEBPZ", "CENPE", "CEP170", "CEP250", "CEPT1", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ3", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENO2", "EPHA7", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERH", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FIGNL1", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTA", "FOXRED1", "FRG1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GID8", "GINS2", "GIPC1", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GOSR2", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK1", "HOOK2", "HOOK3", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LTN1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS2", "MASTL", "MAT2A", "MBOAT7", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED14", "MED21", "MED25", "METAP1", "METTL1", "METTL7B", "MFAP1", "MFN2", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MMS19", "MOB4", "MORF4L1", "MORF4L2", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL38", "MRPL39", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS24", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCEH1", "NCL", "NCOA5", "ND1", "ND5", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA9", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEK3", "NEK9", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARVA", "PATL1", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDXP", "PDZD11", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PIP4K2C", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT2", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1CC", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA2", "PRKACA", "PRKAG1", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPRF", "PUDP", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBM7", "RBMX", "RBMXL1", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIOK2", "RIPK1", "RNASEH2A", "RNF14", "RNGTT", "RNH1", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRM2B", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "S100A10", "S100A11", "SAE1", "SALL2", "SAP18", "SAP30", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCPEP1", "SCYL1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SKP1", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMG1", "SMN1*", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPAST", "SPCS2", "SPCS3", "SPHK2", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF10", "TAF15", "TAGLN2", "TAP1", "TAPBP", "TARS", "TARS2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBPL1", "TCEA1", "TCERG1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM10B", "TIMM22", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM165", "TMEM259", "TMEM38B", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRIP4", "TRIT1", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBIAD1", "UCHL5", "UCK2", "UGCG", "UGGT1", "UNC119", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP28", "USP38", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP6", "UXS1", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VMP1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS72", "VRK1", "VRK2", "WARS", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR34", "WDR4", "WDR74", "WDR82", "WIZ", "WNK1", "WRN", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H15", "ZCCHC11", "ZCCHC8", "ZFPL1", "ZFR", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM4", "ZNF281", "ZNF598", "ZNF622", "ZNF644", "ZNHIT2", "ZW10", "ZYX"], "leading_proteins": ["AAK1", "AARSD1", "ABI1", "ABR", "ACAT1", "ACTR8", "ADD1", "AFDN", "AK3", "ALYREF", "ARHGAP10", "ARID3B", "ARPC4", "ARVCF", "ATF7", "ATP1B1", "ATXN2L", "BCLAF1", "BCR", "BOP1", "BRD2", "BRD3", "BRD4", "BUD31", "CAPZA2", "CBX3", "CD2BP2", "CDC20", "CDC37", "CDC42BPB", "CDC7", "CDK4", "CDKN2AIP", "CEP250", "CHAF1A", "CHAF1B", "CHMP3", "CHTOP", "CKAP5", "CLASP1", "CNOT3", "CNOT4", "COPS8", "CORO1C", "CSNK2B", "CSRP2", "CSTF2", "CTBP1", "CTBP2", "CTNNA1", "CTTN", "CYB5D2", "DBNL", "DCAF13", "DCAF8", "DCP1B", "DCTN2", "DHFR", "DIDO1", "DLST", "DNMT1", "DOCK7", "DPF2", "DST", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "EEF1D", "EHD1", "EHD4", "EIF2S2", "EIF4B", "EIF4G3", "EIF4H", "EPPK1", "EWSR1", "EZH2", "EZR", "FEN1", "FRG1", "G3BP1", "G3BP2", "GATAD2A", "GATAD2B", "GCFC2", "GPATCH4", "GPKOW", "GRSF1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C5", "H1F0", "H1FX", "H2AFX", "H2AFY2", "H4C1*", "HADHB", "HDGF", "HDGFL2", "HDGFL3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HMGA1", "HMGB2", "HMGB3", "HMGN1", "HMGN2", "HNRNPM", "HOOK2", "HOOK3", "HSP90AA1", "HSP90AB1", "HSPE1", "IK", "ILF3", "IQGAP1", "IQGAP3", "ITSN2", "KATNA1", "KDM3B", "KHDRBS1", "KIF18B", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "LAMB1", "LAMC1", "LARP1", "LIMA1", "MAP1B", "MAP1S", "MAP7D1", "MAPK3", "MAPRE2", "MAT2A", "MBOAT7", "MECP2", "MED21", "MED25", "MIA3", "MORF4L1", "MORF4L2", "MPHOSPH10", "MPRIP", "MRPL11", "MRPL12", "MRPL14", "MRPL17", "MRPL2", "MRPL24", "MRPL41", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS35", "MRPS7", "MSH3", "MSN", "MTA2", "MTOR", "MYCBP", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NANS", "NBN", "NCL", "NEK3", "NOL6", "NONO", "NOP10", "NOP14", "NOP9", "NSD1", "NUDC", "NUDCD2", "NUDCD3", "NUP153", "NUP214", "ORC2", "OXSR1", "PACSIN2", "PACSIN3", "PAK4", "PCBD1", "PDCD11", "PDCD4", "PDCD5", "PDLIM1", "PDLIM5", "PDLIM7", "PDXK", "PDZD11", "PGK1", "PHAX", "PHF10", "PHF14", "PHF3", "PKMYT1", "PKN2", "PLEC", "POGZ", "POLDIP3", "POLG", "POLR1C", "POLR2A", "POLR3A", "PQBP1", "PRIM1", "PRPF3", "PRPF4B", "PRRC2A", "PRRC2C", "PSIP1", "PSMD4", "PSMD9", "PSPC1", "PTK7", "QKI", "RACGAP1", "RAD23B", "RANBP1", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM26", "RBM27", "RBM3", "RBMX", "RBMXL1", "RDX", "REPS1", "RHOG", "RNGTT", "RNPS1", "ROCK1", "ROCK2", "RPF1", "RPL11", "RPL13", "RPL13A", "RPL14", "RPL19", "RPL21", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL31", "RPL36A", "RPL5", "RPL6", "RPL7A", "RPL8", "RPRD1B", "RPS14", "RPS15", "RPS19", "RPS24", "RPS28", "RPS5", "RPS6", "RPS7", "RRS1", "RSF1", "RSL24D1", "SALL2", "SAP30", "SAP30BP", "SCAF4", "SCML2", "SEC23B", "SEPT2", "SEPT6", "SERBP1", "SERPINH1", "SF1", "SF3A1", "SFPQ", "SIRT1", "SLC12A2", "SLK", "SMARCD1", "SMARCD2", "SMYD3", "SND1", "SNRNP70", "SNRPA", "SNRPB2", "SNRPD1", "SNRPE", "SNU13", "SNW1", "SPAG9", "SRP19", "SRP54", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SSB", "SSBP1", "STK4", "SUGP2", "SUPT16H", "SUPT6H", "SURF6", "TCERG1", "THRAP3", "TJP1", "TJP2", "TLE3", "TMOD3", "TPM4", "TPX2", "TRAP1", "TRIP4", "TRIT1", "TUBB2B", "TUBG1", "TUBGCP2", "TUBGCP3", "TXLNG", "U2AF1", "UTP14A", "VPS4A", "VPS72", "WASF2", "WDHD1", "WDR33", "WIZ", "YLPM1", "YY1", "ZC3H11A", "ZC3H15", "ZMYM1", "ZMYM2", "ZMYM4", "ZNF622", "ZNF644", "ZYX"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6e0847ffc649d08286e63465c7dfff7898d31ecd --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..788f5c158fb3d6622a577caafd1a3750a8a8d2ab --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2e433e1f8b54366e527c0a4acac610dd105eec8d4763d072fa974b2ac2cfcfb8 +size 223345 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6e0847ffc649d08286e63465c7dfff7898d31ecd --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..64d495b6fd531f7df4816b2719aceb44a2f2a18d --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a935badac02c3a9fc32687c2a5c34172ce1ceb2200e5fdc1719c61e9f5d0e007 +size 131071 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..f0dd1bcad604a5bc20fcff8da5a8f7f5f59d1cd4 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4e368444a981524746f906d847c6176e5b3812d4984a20a87c681b936f0790be +size 90073 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..67bd21f423ad138382bf4b15fd807d2a49107a7b --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tbio 551 2770 6.878625112085641 6.043296214611122e-12 467.6796116504854 2434.25 -0.5416405556668178 0.3215141878443288 119.73666199244032 234.70955636597876 4.704421961664106 0.4116627836259234 1.0 0.0955170285042129 0.0634201030441174 0.0022200906411393 9.55636732291754e-08 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a6317acf0921152c7a5a794208396507bbd258b8 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 907.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8c66d2342245ecedc918123c7094fe5ecacfd250 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..042cf5bef07ca5af27ea7771bd2315a783c25262 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tbio 0.2257693206341057 6.878625112085641 6.043296214611122e-12 2.417318885822536e-11 2.4173188858444486e-11 2770 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551 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..711f330e5590032a3f890de5f7a47d77e8f96b2a --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "ALYREF", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOC1", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIP1", "BRIX1", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf76", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf198", "C1orf35", "C2CD2", "C2CD2L", "C2CD5", "C2orf49", "C3orf58", "C5orf24", "C5orf51", "C8orf33", "C9orf64", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCDC97", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPH", "CENPK", "CENPP", "CENPU", "CENPV", "CEP131", "CEP170", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD2", "COMMD6", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX14", "COX15", "COX18", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERICH1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM160B2", "FAM162A", "FAM173A", "FAM177A1", "FAM207A", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNBP1", "FNBP4", "FNDC3A", "FNTA", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC1", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH11", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KNOP1", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC45", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYRM2", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTF2", "MTFP1", "MTFR1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKBIL1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAWR", "PAX6", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD11", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PXMP4", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "R3HCC1", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN2", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCOC", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLAIN2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG8", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TCP11L1", "TCTN3", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THADA", "THAP11", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM131", "TMEM14C", "TMEM161A", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMA21", "VMP1", "VPS13A", "VPS13D", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR89", "WDR91", "WFS1", "WIZ", 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Q96ST3,Q9UBW7,Q9UIF9,Q9NWH9,Q15059,Q14151,Q14839,Q71F23,Q96ME7,Q96EK4,Q12824,Q96KM6,Q92541,Q9NP66,Q15233,Q9P2D1,P23193,P82094,P20290,Q9H1I8,P17480,O75528,Q8IUF8,Q14966,Q9BQ70,Q12906,Q9UBU8,Q9H981,P29692,O14497,Q9Y2K7,O95104,P25490,Q8N1G0,P23246,P26367,P78347,O14776,Q9UKZ1,Q13045,Q13263,Q9NPA8,Q9HCK8,Q9NYF8,Q96I24,Q96L73,Q8IVW6,P82979,P14373,Q8NEF9,Q9H307,Q5QJE6,Q15906,Q15014,O60885,O60869,Q13573,P51608,P13984,Q9HCD5,Q99543,Q86YP4,Q15637,Q8TDD1,Q92922,Q9HD42,Q5VUA4,Q9UIG0,Q9UER7,Q8IX12,O75175,Q16576,O75446,O43709,P29083,Q9Y2W1,Q04721,Q8WXI9,Q9NYB0,P53999,Q15910,P17096,P26358,P49750,Q99459,Q969X6,Q96EB6,Q9NRL2,Q9H501,Q7LBC6,Q14498,P17544,P26583,Q00059,P18615,Q15291,Q9Y3Y2,O94992,P11142,Q9NRZ9,Q9NPF5,Q9UHR5,Q92785,Q15648,P51858,O95983,Q9HAF1,Q96AE4,Q71SY5,Q14241,Q12830,Q9GZT3,Q9NVC6,P35251,P35269,P41223,Q01844,Q9Y467,Q96IZ0,Q8WXF1,Q9P1Z2,Q13185,Q9H2P0,Q6ZRS2,Q15424,Q96PK6,Q9H582,Q5BKZ1,Q9NQG5,Q8WVM0,Q9NPJ6,Q16513,Q9BXP5,Q9Y5B9,Q9UKM9,O15347,Q8NEY8,Q9UNS1,Q92945,Q96T23,Q9H9T3,Q8WUB8,Q6P1J9,Q12972,P06733,Q6P1N0,Q00839,Q13503,Q01664,Q9UPT9,Q9NX63,Q99496,Q9NX58,O00291,Q07666,P32780,O75475,P09874,Q86U86,Q8N7H5,Q8TAQ2,Q9NUQ3,Q92499,O00267,P25440,O60828,Q13112,Q15650 168 +mRNA splicing 0.4688481580629582 3.0080215563845423 0.0026295448536017 0.3708650129854047 0.0420727176576285 186 Q9Y3C6,P38159,Q15233,P52272,Q66PJ3,Q13523,P98175,Q96PU8,P08579,O43290,Q99590,P23246,Q08170,Q9ULR0,Q13769,Q7L014,O43395,Q9UQ35,Q15007,Q01130,O75494,Q9Y2W2,Q96DF8,Q9H307,Q13573,Q96E39,Q15637,Q9H2H8,P26599,Q9P013,O75400,Q9Y2W1,P16383,Q99459,Q92917,Q14498,P55081,P11940,Q02040,Q9BW85,Q15287,Q9H7Z3,Q05519,P11142,Q15459,Q14331,Q9H7N4,P09012,Q13243,Q13435,Q8WYA6,P62314,Q9NW13,P41223,O95400,Q96SB4,P49756,P55769,Q9BUQ8,P84103,Q01081,Q5BKZ1,Q9UKM9,P18583,Q9Y3B4,Q13123,Q92945,Q8IX01,Q12972,P62304,Q00839,O95232,Q9UKV3,Q96I25,Q96NC0,Q9NW64,Q9UHI6,P51991,O60828 79 +Spermatogenesis 0.5273651216027556 2.8938385811645952 0.0038056374735955 0.4888386224288481 0.0515224765656009 30 Q9BY67,Q9UPN4,Q9H0H5,Q6P6C2,Q14141,Q9P0K7,Q15019,Q9H8Y8 8 +Ribosome biogenesis 0.4035020328766785 2.728909573689497 0.0063544125894696 0.6743542203634425 0.0627224196036591 70 O60832,Q14331,P46087,Q9NV06,Q2NL82,O43709,Q9NZM5,Q15050,Q9NVU7,Q9UHA3,Q9BVJ6,Q8IY81,Q9NPE3,Q99848,P78316,Q7L2E3,Q9H9Y2,O00566,Q14692 19 +mRNA processing 0.4558785473353984 2.6730834187294907 0.0075157558561838 0.7349320041555907 0.0661386515344174 216 Q9Y3C6,O95319,P38159,Q15233,Q05048,P52272,Q66PJ3,Q13523,P98175,Q96PU8,P08579,O43290,Q99590,P23246,Q08170,Q9ULR0,Q13769,Q7L014,O43395,Q9UQ35,Q15007,Q01130,O75494,Q9Y2W2,Q96DF8,Q9H307,Q13573,Q96E39,Q15637,Q9H2H8,P26599,Q9P013,O75400,Q9Y2W1,P08621,P16383,Q99459,Q9C0J8,Q92917,Q14498,P55081,P11940,Q02040,Q9BW85,Q15287,Q9H7Z3,Q05519,P11142,Q6UN15,Q15459,Q14331,Q9H7N4,P09012,Q13243,Q13435,Q8WYA6,P62314,Q9NW13,P41223,O95400,Q12849,Q96SB4,P49756,P55769,Q9BUQ8,Q53F19,O60942,P84103,Q01081,Q5BKZ1,Q9UKM9,P18583,Q9Y3B4,Q13123,Q92945,Q8IX01,Q12972,P62304,Q00839,O95232,Q9UKV3,Q96I25,Q96NC0,Q9NW64,Q9UJV9,Q9UHI6,Q92499,P51991,P33240,O60828 90 +mRNA transport 0.3817921553705328 2.35665312847671 0.0184404630006767 0.9622140898167104 0.1082965017646051 68 O75152,Q9UKX7,Q9Y6M1,Q8WYP5,Q8TD16,P49790,Q92945,Q9NZI8,P12270,P55735,Q96PU8,P35658,Q9NPA8,Q9BY77,Q13769,Q8NFH5,Q53F19,P82979,Q9BZI7,O00159 20 +Cell shape 0.7773916688039446 2.3277974327622895 0.0199228624705161 0.971039538113181 0.1095757435878386 7 P35579,Q7Z406,P35580 3 +rRNA processing 0.3530871866919104 2.104634020760476 0.0353231778333649 0.9982167815255728 0.1571937961120411 73 Q8WVM0,O60832,Q14331,P46087,Q9NV06,Q9HC36,Q9NR30,Q9P2D1,O43709,Q99547,Q14137,Q14690,Q8IY81,Q9NPE3,Q969X6,Q76FK4,O43818,P78316,Q9H9Y2,O00566,Q9Y2W2 21 +Cilium biogenesis/degradation 0.4291706050142708 2.064105886463609 0.0390076779781263 0.999090703461733 0.1634607458131007 34 Q9UPN4,Q15051,Q16513,Q9H4M9,Q9Y366,Q9BV73,P21333,Q8NCM8,O15078 9 +Innate immunity 0.368858958545233 2.0268468094813925 0.0426780816366789 0.9995363306109212 0.1707123265467158 62 Q13283,P04083,O60858,O15347,O75179,Q6SZW1,Q92974,Q9NR30,Q15233,P23246,Q8WXF1,Q7Z434,Q96PK6,P26583,P78540,O14802,P43243,Q92499,O60828 19 +Glyoxylate bypass 0.976019845644986 2.002131257436351 0.0452706165579459 0.9997123059685888 0.177058411426633 2 P48735 1 +Meiosis 0.5242023170797612 1.929335574177581 0.0536892161367541 0.9999394733134204 0.1886067366650831 16 P16104,O60934,Q5VUA4,Q92878,Q14683 5 +Biological rhythms 0.3867577474634383 1.9102971418851389 0.0560949655736369 0.999961329371355 0.1886067366650831 45 Q96ST3,P23246,Q15910,P42345,P11387,Q9Y2W1,Q8WXF1,O75592,Q96EB6,Q13185,Q7Z6Z7,Q9UNS1,Q9Y2K7,Q15233 14 +One-carbon metabolism 0.604749309546622 1.8893311632065184 0.0588474683276643 0.9999768706937088 0.1917991560309058 10 P13995,P00374,Q6UB35,Q9NZL9,Q9H9B4 5 +Myogenesis 0.6642675349512023 1.5632447200486317 0.1179950451874087 0.9999999997471282 0.3104226121008567 6 Q14331,O75369 2 +Differentiation 0.322116689958719 1.5323172070126545 0.1254441769748107 0.9999999999431662 0.3188639266668143 102 Q9BY67,Q9UPN4,Q12834,O60869,Q9H0H5,Q9P0K7,Q9NZM3,Q7Z6Z7,Q96N67,Q6SZW1,Q92974,Q6P6C2,Q04721,Q14141,Q14444,P16949,Q96PU8,P25490,O00291,O75369,Q13769,Q15019,Q9H8Y8,Q9NR12,P54652 25 +Immunity 0.30052308214646 1.5267592826454883 0.1268208799243011 0.9999999999569288 0.3188639266668143 81 Q9BY67,Q13283,P04083,O60858,O15347,O75179,P30511,Q6SZW1,Q92974,Q9NR30,Q15233,Q13740,P23246,Q8WXF1,Q7Z434,P04406,Q96PK6,P26583,P78540,O14802,Q8WXW3,P43243,Q92499,O60828,O94992 25 +Tricarboxylic acid cycle 0.4191569655270443 1.319611600730698 0.1869647276811448 1.0 0.4387438942917531 20 P40925,O43837,P31040,Q96I99,P53597,P11177,O75874,P36957,P48735,Q99798 10 +DNA recombination 0.3732543966875593 1.2953347756170988 0.1952047676666528 1.0 0.4520531461754066 26 P16104,P26583,P49916,Q15233,Q9H981,P25490 6 +Hearing 0.7979603087100364 1.2494542258462624 0.2114989856462668 1.0 0.4834262529057526 2 Q9UM54 1 +Cell adhesion 0.3194013860377725 1.0445404899169364 0.2962353962467816 1.0 0.6111358284070342 41 Q9BY67,Q16513,Q13308,P11047,P19022,P05026,P35579,P07942,P35580,P18206 10 +Mitosis 0.3090514157513639 1.0273589240942411 0.3042514857062373 1.0 0.6111358284070342 123 Q12834,Q96CS2,Q9UNS1,Q9Y448,P12270,Q9Y5K6,P09496,Q9H981,Q7Z7K6,Q14008,Q9NQS7,Q14203,Q9Y6D9,Q9UQE7,O43491,Q14980,Q15019,Q9Y6A5,P51956,Q9HC35,Q9H7Z3,Q08379,O95347,Q8NBT2,Q14683 25 +DNA replication 0.2981272498335754 1.0137783232275197 0.3106885409579545 1.0 0.6111358284070342 57 Q7Z6E9,Q8WVB6,Q04837,Q16576,Q13416,P25205,P49916,Q9Y5B9,Q9BRX5,P54098,Q13111,P33991,P54132,P35251,Q13112,P39748 16 +Proline biosynthesis 0.6410540428484781 0.9881864284211536 0.3230613535726458 1.0 0.6111358284070342 4 Q96C36,P54886 2 +Cell cycle 0.3605325352153684 0.9856207602368564 0.3243192467416445 1.0 0.6111358284070342 239 Q8WVB6,Q9UPN4,Q9NRZ9,P46013,Q9Y3E7,Q12834,Q8WYP5,Q9BRX2,Q9H0H5,Q8WWK9,Q8NBT2,Q9UHD8,Q16513,P18583,Q7Z4H7,Q96CS2,Q14676,Q9UNS1,Q92974,Q9HD42,Q15398,Q9UN37,P40818,Q13564,Q7Z3K3,Q8IX12,O75400,P12270,P25205,O60934,Q9Y448,Q13526,Q02241,Q9Y5K6,Q14141,Q9BV73,P09496,Q9H981,Q8TAE8,Q7Z7K6,Q92878,Q14008,Q9NQS7,Q8WW12,P16104,Q14203,Q9Y6D9,Q9UQE7,O43491,Q9UPT9,Q14980,Q99459,Q99640,Q13111,P33991,Q9ULW0,Q9Y6G9,Q15019,Q96CT7,Q9Y6A5,Q8IXM3,Q92733,P51956,Q15007,O00311,P49916,P51610,Q9HC35,Q9H7Z3,P53990,O96013,Q08379,O95347,Q13112,Q96EE3,Q14683 76 +DNA repair 0.3020092432252525 0.9813866840915024 0.3264020901719386 1.0 0.6111358284070342 118 Q15014,Q7Z6Z7,P20585,P18887,Q14676,Q9UNS1,P39748,Q15233,O60934,Q9H981,P61088,Q92878,P25490,P16104,P23246,Q9UQE7,Q99459,Q13111,P54132,Q96T60,P09874,P49916,Q9H1E3,Q13112,Q14683 25 +Sodium transport 0.5244045969866432 0.8883685073709848 0.3743425598133174 1.0 0.6556763797769838 6 P05026 1 +Neurogenesis 0.2865641408589178 0.8622082987915725 0.3885729037807928 1.0 0.6704787359354856 56 Q8WUJ1,Q12834 2 +Wnt signaling pathway 0.3103919134023883 0.8174106526780267 0.4136937899851056 1.0 0.6989702590427682 32 Q13308,Q92541,Q8NBM4,Q9HCK8 4 +Tetrahydrobiopterin biosynthesis 0.6717199558985831 0.7306050416834021 0.4650204316413739 1.0 0.7147034290464226 2 P09417 1 +DNA damage 0.2974202722231209 0.7224501127556188 0.4700177862775563 1.0 0.7147034290464226 134 Q15014,O60885,Q7Z6Z7,P20585,P18887,Q14676,Q9UNS1,P39748,Q15233,Q7Z6E9,O60934,Q9H981,P61088,Q96QE3,Q92878,P25490,P16104,P23246,Q9UQE7,Q99459,Q13111,P54132,Q96T60,P09874,P49916,Q9H7Z3,Q9H1E3,P55072,Q13112,Q14683 30 +Translocation 0.2748152370046191 0.7141808647135431 0.4751153477183605 1.0 0.7147034290464226 54 P12270,Q8TD16,Q9NPA8,P49790,O00159,Q9P2E9,P35658 7 +Cell division 0.3031356957390922 0.5126319083643742 0.6082088286078782 1.0 0.8234211833460504 166 Q8NBT2,Q9NRZ9,Q9Y3E7,Q12834,Q8WYP5,Q9BRX2,Q9H0H5,Q16513,Q9UHD8,Q7Z4H7,Q96CS2,Q9UNS1,Q9HD42,Q92974,Q9UN37,Q7Z3K3,Q9Y448,P12270,O75400,Q02241,Q9Y5K6,Q14141,P09496,Q9H981,Q7Z7K6,Q14008,Q9NQS7,Q14203,Q9Y6D9,Q9UQE7,O43491,Q14980,Q9ULW0,Q9Y6G9,Q15019,Q96CT7,Q9Y6A5,P51956,O00311,P49916,Q9HC35,Q9H7Z3,P53990,Q08379,O95347,Q96EE3,Q14683 47 +Chromosome partition 0.2975581675162044 0.4135861449017723 0.6791772218103254 1.0 0.8789352282251269 20 Q9NQS7 1 +Methionine biosynthesis 0.5878136200716809 0.3896059008525528 0.6968279880471653 1.0 0.882314574793533 3 Q99707,Q9BV20 2 +Nonsense-mediated mRNA decay 0.2910955338360011 0.3255822003984031 0.7447404810490148 1.0 0.923058624398779 16 Q9BZI7,Q9HAU5,P11940,Q8IZD4 4 +Growth regulation 0.2987488985541784 0.2720591030484293 0.7855765748762706 1.0 0.9668634767707946 13 Q15014 1 +Antiviral defense 0.2383911251349919 0.2224001314179543 0.8240024095254677 1.0 0.99677921595956 29 Q53F19,O14802,Q9NUQ8,Q9NV70,Q12906,Q92499,Q7Z434,Q9NR30 8 +Endocytosis 0.2281756823965166 0.2114486647964803 0.8325371860571325 1.0 0.99677921595956 45 Q9NVZ3,Q14677,Q9UM54,Q2M2I8,O75146,Q9NZM3,O00291,Q9UKS6,Q14247,Q9UNF0 10 +Amino-acid biosynthesis 0.268206474116529 0.1561790227809648 0.8758919112190442 1.0 1.0 13 Q96C36,P17174,P32322,P54886,Q99707,Q9BV20,P32929 7 +Complement pathway 0.4707828004409992 0.1335220128696804 0.893780556384919 1.0 1.0 2 Q07021 1 +DNA condensation 0.3043311948165202 0.1281041193691866 0.8980665761258322 1.0 1.0 7 O95347 1 +DNA excision 0.447477253928862 0.0914518222363311 0.9271335860361676 1.0 1.0 3 P28340,Q9UQ84 2 +Inflammatory response 0.2521031026584854 0.0855686588220504 0.931809313687782 1.0 1.0 11 P04083,P26583 2 +Glycogen biosynthesis 0.3157875688332203 0.0647148593078906 0.9484010316067526 1.0 1.0 5 P13807 1 +Glutathione biosynthesis 0.4116349600220518 0.0533097265534492 0.957485130554327 1.0 1.0 3 P48507,P48506 2 +Phagocytosis 0.2698550019872024 0.0118207262562134 0.9905686446630716 1.0 1.0 4 Q96JJ3 1 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..76928b44eb1eb109ad34792650eb4f818f72005c --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Bile acid catabolism", "Biological rhythms", "Biomineralization", "Blood coagulation", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Cysteine biosynthesis", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Hemostasis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Menaquinone biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyridoxine biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF3", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ACTR8", "ADA", "ADAM17", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMFR", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEX1", "API5", "APOBEC3C", "APOC1", "APOL2", "APOO", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL8B", "ARMC10", "ARMT1", "ARRB2", "ARV1", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AUP1", "AURKA", "AURKB", "BABAM2", "BAG3", "BAG6", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD2L", "C2CD5", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC86", "CCDC93", "CCDC94", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC42", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPU", "CENPV", "CEP131", "CEP250", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLSTN3", "CLTA", "CLTC", "CLU", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COMMD2", "COMMD6", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPS7B", "COPZ1", "COQ3", "COQ8A", "CORO7", "COX1", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CROT", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENND4C", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPY30", "DPYSL2", "DSC3", "DSG2", "DST", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM162A", "FAM208A", "FAM50A", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FNBP1", "FOXRED1", "FRG1", "FRYL", "FTSJ3", "FUBP1", "FUBP3", "FUNDC1", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCC2", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGPS1", "GHITM", "GID8", "GINS2", "GINS3", "GINS4", "GLRX", "GLTP", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HIP1", "HIP1R", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLTF", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK1", "HOOK2", "HOOK3", "HPF1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILVBL", "IMP3", "IMP4", "IMPACT", "IMPDH1", "IMPDH2", "INA", "INCENP", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KATNA1", "KCTD21", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDLR", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMBRD1", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC41", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGT1", "MANF", "MAP1S", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MESD", "METTL1", "MFAP1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MLEC", "MMGT1", "MMS19", "MOB4", "MOCOS", "MOCS1", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP5", "MRE11", "MRI1", "MRM3", "MRPL41", "MRPL58", "MRPS27", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTERF3", "MTFP1", "MTG1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCEH1", "NCK1", "NCKAP1", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK3", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NMD3", "NME1", "NME2", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRDE2", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUBP2", "NUCKS1", "NUDC", "NUDT16", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PARVA", "PAWR", "PAX6", "PAXBP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH7", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDZD8", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PMF1", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "PPAT", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R8", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKCD", "PRKDC", "PRKRA", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPMT1", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PURA", "PUS1", "PUS7", "PWP1", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RANBP6", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM15", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN3", "RMI1", "RMND1", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP14", "RPP30", "RPP40", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RTCB", "RTF1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SCYL1", "SDAD1", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG8", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SON", "SORBS3", "SORT1", "SPAST", "SPATA5", "SPC24", "SPDL1", "SPEN", "SPNS1", "SPTLC1", "SPTLC2", "SRCAP", "SRFBP1", "SRM", "SRPK1", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STK26", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "SYS1", "TACC3", "TADA3", "TAF10", "TALDO1", "TAMM41", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBCB", "TBL1XR1", "TBPL1", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCTN3", "TDRKH", "TECR", "TEFM", "TERF2IP", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TK1", "TLE3", "TLN1", "TM7SF2", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM14C", "TMEM206", "TMEM214", "TMEM30A", "TMEM38B", "TMEM59", "TMF1", "TMX1", "TMX4", "TNFAIP8", "TNPO1", "TNPO2", "TNPO3", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TP53", "TP53BP1", "TPI1", "TPR", "TPRKB", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSNAX", "TSR1", "TTC19", "TTC26", "TTC4", "TTF2", "TTLL12", "TTYH3", "TUBB2B", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC15", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBL5", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VMP1", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WDR12", "WDR33", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR5", "WDR6", "WDR61", "WDR75", "WLS", "WRAP73", "WRN", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIPF3", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YTHDC1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YY1", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFPL1", "ZMAT2", "ZMYM2", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AAK1", "ABCF3", "ACIN1", "ACO2", "ACTR8", "ADNP", "AHCTF1", "AKAP17A", "ALCAM", "ALDH18A1", "ALKBH5", "ANKRD17", "ANXA1", "ARG2", "ARHGEF2", "ARID1A", "ARID3B", "ARL6IP4", "ASCC2", "ATAD5", "ATF7", "ATP1B1", "BAZ1A", "BAZ1B", "BAZ2A", "BCLAF1", "BICD2", "BLM", "BMS1", "BOP1", "BPTF", "BRD2", "BRD3", "BRD4", "BTF3", "BUD23", "BUD31", "C1QBP", "CADM1", "CALCOCO1", "CAPRIN1", "CBX3", "CC2D1A", "CCAR1", "CCDC124", "CCDC94", "CD2AP", "CD2BP2", "CDC20", "CDC5L", "CDC7", "CDC73", "CDH2", "CELF2", "CENPU", "CENPV", "CEP131", "CEP250", "CEP290", "CHAF1A", "CHAF1B", "CHCHD3", "CHD4", "CHD7", "CHD8", "CHMP1A", "CHMP3", "CHTF18", "CHTOP", "CKAP2", "CKAP5", "CLINT1", "CLTA", "CNOT11", "CNOT3", "CSTF1", "CSTF2", "CTH", "CTNNBL1", "CTTN", "CWC15", "CYB5D2", "DAXX", "DCAF13", "DCP1B", "DCTN1", "DDX1", "DDX20", "DDX21", "DDX23", "DDX41", "DDX46", "DDX54", "DHFR", "DHX30", "DKC1", "DLGAP5", "DLST", "DMAP1", "DNAJC2", "DNMT1", "DNTTIP2", "DOCK7", "DPF2", "DYNC1LI1", "DYNC2H1", "EBNA1BP2", "EDF1", "EEF1D", "EHD1", "ELMO2", "ELOA", "ELP3", "EML4", "ENO1", "ENY2", "EPB41L2", "ESF1", "ESS2", "EWSR1", "EXO1", "EXOC1", "EZH2", "FEN1", "FIP1L1", "FLII", "FLNA", "FLNB", "FRG1", "FTSJ3", "FUBP1", "FUBP3", "G3BP1", "GADD45GIP1", "GAPDH", "GATAD2A", "GATAD2B", "GCFC2", "GCLC", "GCLM", "GINS3", "GOLGA2", "GORASP2", "GOT1", "GPKOW", "GRSF1", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C2", "GTF3C5", "GYS1", "H2AFX", "HAUS1", "HAUS6", "HCFC1", "HDGF", "HELLS", "HEXIM1", "HIP1", "HIP1R", "HLA-F", "HLTF", "HMG20A", "HMGA1", "HMGB2", "HMGB3", "HNRNPA3", "HNRNPM", "HNRNPU", "HSPA2", "HSPA8", "HUWE1", "IDH1", "IDH2", "IDH3B", "IFT52", "IGF2BP1", "IGF2BP2", "IK", "ILF3", "INCENP", "IQCB1", "IST1", "ISY1", "ITSN2", "KDM2A", "KDM3B", "KHDRBS1", "KHSRP", "KIF23", "KNSTRN", "LAMB1", "LAMC1", "LIG3", "LUC7L3", "LYAR", "MAD1L1", "MAT2B", "MATR3", "MAVS", "MBD3", "MCM3", "MCM4", "MDC1", "MDH1", "MEAF6", "MECP2", "MED1", "MED17", "MED21", "MED25", "MED4", "MFAP1", "MKI67", "MORF4L1", "MORF4L2", "MPHOSPH10", "MPHOSPH6", "MRI1", "MRM3", "MRPL41", "MSH3", "MTHFD1L", "MTHFD2", "MTOR", "MTR", "MYCBP2", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO6", "NAE1", "NBN", "NCBP3", "NCOA5", "NECAP2", "NEK3", "NELFE", "NOL8", "NONO", "NOP10", "NOP14", "NOP2", "NOP53", "NOTCH2", "NRDE2", "NSD1", "NUCKS1", "NUMA1", "NUP153", "NUP214", "NUP35", "NUP50", "ORC2", "PABPC1", "PACSIN2", "PACSIN3", "PAF1", "PAK4", "PARP1", "PAWR", "PAX6", "PBRM1", "PCNP", "PDCD11", "PDHB", "PDLIM7", "PELO", "PHF10", "PIBF1", "PIN1", "PKMYT1", "PKN2", "PNKP", "PNN", "POGZ", "POLD1", "POLDIP3", "POLG", "POLR1C", "POLR3A", "POLRMT", "PPHLN1", "PPIL1", "PPIL3", "PPP1R8", "PQBP1", "PRCC", "PRIM1", "PRPF3", "PRPF40A", "PRPF4B", "PSIP1", "PSPC1", "PTBP1", "PTK7", "PYCR1", "PYCR2", "QDPR", "QKI", "RACGAP1", "RAD50", "RAI14", "RALY", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM17", "RBM22", "RBM25", "RBM28", "RBM39", "RBMX", "RBMXL1", "RFC1", "RIOX2", "RNF2", "RNGTT", "RNPS1", "RPAP1", "RPF1", "RPRD1B", "RRBP1", "RRP9", "RRS1", "RSF1", "RSL24D1", "RTF1", "SAFB", "SAFB2", "SALL2", "SAP30", "SAP30BP", "SARM1", "SARNP", "SART1", "SCAF1", "SCAF11", "SCAF4", "SDAD1", "SDHA", "SEC13", "SEH1L", "SEPT2", "SEPT6", "SEPT9", "SF1", "SF3A1", "SF3B2", "SF3B6", "SFPQ", "SFXN1", "SIN3A", "SIRT1", "SLIRP", "SLTM", "SMARCB1", "SMARCC1", "SMARCC2", "SMC1A", "SMC2", "SMC3", "SNRNP70", "SNRPA", "SNRPB2", "SNRPD1", "SNRPE", "SNU13", "SNW1", "SON", "SPC24", "SRCAP", "SRFBP1", "SRPK1", "SRRM2", "SRRT", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SSBP1", "STMN1", "SUB1", "SUCLG1", "SUCLG2", "SUGP2", "SUPT16H", "SUPT5H", "TACC3", "TADA3", "TCEA1", "TCERG1", "TCF25", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "THAP11", "THOC5", "THRAP3", "TIMELESS", "TMF1", "TOP1", "TPR", "TPX2", "TRIM13", "TRIM27", "TRIM28", "TRIP4", "TSR1", "TXLNG", "U2AF1", "UBAC2", "UBE2N", "UBTF", "UPF2", "UPF3B", "USP22", "USP8", "UTP14A", "UTP4", "VCL", "VCP", "VPS4A", "VPS72", "WBP11", "WDR33", "WTAP", "XRCC1", "YLPM1", "YY1", "ZC3H11A", "ZMAT2", "ZMYM2", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687"]} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/idx2term.json b/protein_atlas_disease_involvement/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..833c0bafc28c8fcae0efbea6241f977c9cbdbb48 --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Diamond-Blackfan anemia"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/plot_0.png 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setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Diamond-Blackfan anemia 6 16 2.616246179354079 0.0088902434524138 7.868932038834951 16.179611650485437 -0.5155383396532162 0.3989758925571296 3.47561628609903 1.0666032850274074 1.2519995222007774 0.3390131790640212 1.0 1.0 0.1709159600444602 0.0779048373986419 1.8924379158190217e-05 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cd4efc8c0a6278cb0251bd9a2bf23f741f996cff --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 119, + "title": "Average number of proteins per term", + "value": 23.57983193277311 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..976e0baea937dfe813fa2aa3fabf5b511d937ce6 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8502b1e3ead1e59d0c66a83cdb7255b4c3fd2052 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,30 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Diamond-Blackfan anemia 0.6236536248506135 2.616246179354079 0.0088902434524138 0.6544678883064171 0.132242371354656 16 P61254,P62273,P62913,P62081,P62857,P39019 6 +Senior-Loken syndrome 0.9729878721058464 1.9895085899026703 0.0466450946327521 0.9966014156240814 0.3469228913310939 2 O15078 1 +Leber congenital amaurosis 0.8684346070281035 1.9429919947381464 0.0520171255558798 0.9982651636224108 0.3641198788911592 4 O15078 1 +Bardet-Biedl syndrome 0.7247423300773992 1.8517715945407347 0.0640586282229749 0.9996210440298378 0.3705901473312288 6 Q13049 1 +Nephronophthisis 0.9143377145888864 1.5828428612031304 0.1134572848048605 0.9999994026069076 0.4415573131261491 3 O15078 1 +Limb-girdle muscular dystrophy 0.5305055406170425 1.510852678154169 0.1308259898227839 0.9999999432845909 0.4601137136006922 11 Q13049,P02545,O75190,Q15149 4 +Ciliopathy 0.4490916891913369 1.508365291766483 0.1314610610287692 0.999999948009264 0.4601137136006922 19 Q13049,Q9Y366,Q15051,O15078 4 +Microphthalmia 0.6054589969907404 1.466009597668181 0.1426456721735443 0.9999999888806091 0.4608183811118383 7 O60493,Q9NP58 2 +Obesity 0.5211321566742597 1.393826942840256 0.1633698699730674 0.9999999993953744 0.4723054361165414 10 Q13049 1 +Proto-oncogene 0.335332199818651 1.3045167534122206 0.1920574511149426 0.9999999999904878 0.4761424308891286 45 P46108,P11387,Q12802,P12270,Q9BZE9,P35658,Q01844,P06748,Q96T37,P11274,Q99961,O94979,Q96L73,Q92733,Q16204,P55196,P14373,Q15154,Q5M775 19 +Tumor suppressor 0.3569072469374243 1.2396537880967744 0.2151034766137654 0.999999999999696 0.4941506848111833 29 Q8IVW6,Q9BY67,Q9H307,Q53EL6,Q86U86,P31040,Q9Y2J2,Q8N7H5,P54277,Q6P1J9,P38159,Q05655 12 +Williams-Beuren syndrome 0.5128411046837393 1.1682559827416064 0.2427035248074003 0.9999999999999956 0.5251221718560116 8 Q8NFV4,Q15056,Q9UIG0 3 +Dyskeratosis congenita 0.5818429597595965 0.9338364038067776 0.350388287997766 1.0 0.6131795039960906 5 Q9NPE3,Q9NP58 2 +Amyotrophic lateral sclerosis 0.4074995383175269 0.879343148225176 0.37921524735043 1.0 0.6375981094690372 13 P43243,Q14203,Q9UQN3 3 +Cancer-related genes 0.3004909670024606 0.7720325081081728 0.4400951739834569 1.0 0.7105938919253652 397 Q96ST3,Q9UBW7,P46013,Q12834,P00374,Q15059,P38159,Q14676,P48735,P07942,Q15233,Q9P2D1,P82094,P25205,P62841,Q12906,P25685,P98175,Q96PU8,P61088,O43290,P06748,P23246,Q96T37,Q14980,Q9HCK8,P54132,O75874,P55036,Q15149,Q9NYF8,Q96L73,Q92733,Q9UDY2,Q13442,Q01130,P55196,P14373,P04083,Q8IZP0,O60885,P11387,P51608,Q99543,P18887,P61604,P40818,P62805,Q9UER7,Q8IX12,P12270,O75175,O60934,P68402,Q04721,Q16543,Q16881,Q86VS8,Q9BZE9,P35658,Q15910,P11274,P17096,P11047,Q9ULW0,P35579,P61353,O60610,P11940,P78540,P67870,P22314,Q9H7B4,Q6UN15,Q02952,Q15648,P78332,Q96AE4,Q86UP2,P16949,Q01844,O43815,Q15056,Q15019,Q9H2P0,Q5VU43,P11166,P54652,Q14683,P09104,Q7Z6Z7,P39748,P33176,Q13526,O75146,P15311,Q14247,Q14203,Q9UQE7,O00291,P02545,P46777,O75475,P09874,P42345,Q9HC35 106 +Non-syndromic deafness 0.3484138931406424 0.7661351920169047 0.4435958651277505 1.0 0.7105938919253652 20 P35579,Q7Z406 2 +Premature ovarian failure 0.6769570011025289 0.7510510011756646 0.4526219626922911 1.0 0.7105938919253652 2 Q06787 1 +Autism 0.4945453830923155 0.7490539807273683 0.4538246704733424 1.0 0.7105938919253652 6 Q9HCK8 1 +Autism spectrum disorder 0.3728659405161585 0.7353233951894924 0.4621425633294442 1.0 0.7142203251455047 14 P51608,Q9HCK8 2 +Hereditary nonpolyposis colorectal cancer 0.614659141985817 0.4707458505101448 0.6378222376207916 1.0 0.8625096167826614 3 P54277 1 +Lissencephaly 0.3295812813180011 0.4194318461170844 0.6749005540102466 1.0 0.8825622629364764 13 P07942 1 +Epidermolysis bullosa 0.5785016209201868 0.3629662081299792 0.716630127369803 1.0 0.8972474346747185 3 Q15149 1 +Cardiomyopathy 0.266983908341047 0.3424856219078984 0.7319854625585862 1.0 0.8972474346747185 25 Q9UM54,P19022,Q14315,P18206 4 +Emery-Dreifuss muscular dystrophy 0.4314977732415908 0.3341094415868406 0.7382969757118039 1.0 0.8972474346747185 5 P02545 1 +Osteogenesis imperfecta 0.3318040066039948 0.3016905489605377 0.7628879736276917 1.0 0.9170067561787404 9 Q96AY3 1 +Mental retardation 0.2893048244076497 0.2493234735258509 0.8031105752755319 1.0 0.936962337821454 182 Q96ST3,P51608,P18583,P38159,Q7Z6Z7,Q92785,Q13049,Q92974,O15078,Q6UX04,Q15233,P17480,Q12830,Q8WXI9,Q96JM3,P19022,Q9Y2V7,Q9BSJ2,Q13813,Q9NW13,Q6PJT7,Q6P1N0,P25490,Q13409,P10412,Q9UQE7,Q9H1B7,O60826,Q7LBC6,Q9H2P0,Q9GZZ9,Q96T60,P11166,P42345,P51610,Q8N201,Q9BZI7,O60828,Q14683 39 +Cone-rod dystrophy 0.489850075600423 0.1564416954528938 0.875684873531118 1.0 0.965490921339714 3 Q9BV73 1 +Retinitis pigmentosa 0.2504806015939828 0.1557325215975357 0.8762438613839423 1.0 0.965490921339714 18 O43395 1 +Glutaricaciduria 0.3488692774407189 0.0742593934578355 0.9408039871081896 1.0 0.973527604051083 4 P13804,Q92947,P38117 3 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bc5935cd658f1e604f73b2a9648896cb40142d78 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary multiple exostoses", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Peters anomaly", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD4", "ABHD11", "ABHD12", "ABI1", "ACAA1", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA7", "AP1B1", "AP1S1", "AP1S2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP4M1", "APEX1", "APOC1", "APOL2", "APP", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARV1", "ASAH1", "ASCC1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG5", "ATIC", "ATL3", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATPAF2", "ATRX", "ATXN10", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BBS4", "BCAP31", "BCAS3", "BCAT2", "BCKDK", "BCLAF1", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD3", "BRD4", "BRI3BP", "BRIP1", "BUB1B", "BUD23", "C12orf57", "C19orf70", "C1QBP", "C3orf58", "CAD", "CADM1", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN5", "CARM1", "CARS", "CASK", "CAST", "CC2D1A", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCT5", "CD320", "CDC20", "CDC27", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKAL1", "CENPE", "CEP250", "CEP290", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CLU", "CNNM4", "CNOT1", "CNOT3", "COA3", "COA7", "COASY", "COG5", "COG6", "COG7", "COG8", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COX1", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTH", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCAF8", "DCK", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLG3", "DLST", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DSC3", "DSE", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF2S3", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "FADS2", "FAF1", "FAH", "FAM120A", "FAM3C", "FAM50A", "FANCG", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GAL", "GALK1", "GALM", "GALNS", "GALNT2", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GCDH", "GCLC", "GCLM", "GDAP2", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GGPS1", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI3", "GNAO1", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GPRASP2", "GPT2", "GRB2", "GSK3A", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2H1", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H3-3A*", "H4C1*", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIP1", "HIP1R", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGCR", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOOK3", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT52", "IGBP1", "IGF2R", "IGHMBP2", "IKBKB", "ILF3", "ILK", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INTS1", "IPO7", "IQCB1", "IRF2BPL", "IRS4", "ITGA2", "ITGAV", "ITGB1", "ITPA", "IVD", "JAGN1", "JAM3", "JUP", "KARS", "KCTD21", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIDINS220", "KIF11", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KLC2", "KNSTRN", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LGMN", "LIPA", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRPPRC", "LRSAM1", "LSS", "LTA4H", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAGED2", "MAGT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MARS", "MARS2", "MASTL", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MECR", "MED1", "MED17", "MED23", "MED25", "MESD", "MFN2", "MFSD8", "MICU1", "MID1", "MIF", "MIPEP", "MKI67", "MMAB", "MOCOS", "MOCS1", "MOGS", "MPDU1", "MPI", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYH10", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NADSYN1", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCKIPSD", "NCSTN", "ND1", "ND5", "NDE1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA6", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEFL", "NEK9", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NME2", "NNT", "NONO", "NOP10", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSBPL2", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B2", "PANX1", "PARK7", "PARN", "PARP1", "PARP2", "PAX6", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDAP1", "PDCD4", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDP1", "PDSS1", "PDSS2", "PDXK", "PEPD", "PEX14", "PEX19", "PEX5", "PEX6", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIN1", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POMGNT2", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PTDSS1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "RAB10", "RAB11B", "RAB18", "RAB23", "RAB3GAP2", "RAB7A", "RAB8A", "RABEP1", "RABL3", "RAC1", "RAD21", "RAD23B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBM7", "RBMX", "RDH11", "RDX", "REEP2", "REPS1", "RFC1", "RFC2", "RFK", "RFT1", "RHEB", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF213", "ROCK1", "ROCK2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS28", "RPS29", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRM1", "RRM2", "RRM2B", "RTN2", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SART1", "SBDS", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SCYL1", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC33A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC9A3R1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SNAP29", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPAST", "SPATA5", "SPECC1", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRP54", "SRP72", "SRSF2", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD3", "STAT1", "STAT3", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SV2A", "SYNE2", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCOF1", "TCTN3", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIMM17A", "TIMM22", "TIMM50", "TIMMDC1", "TJP2", "TK1", "TKFC", "TKT", "TMCO1", "TMEM126B", "TMEM165", "TMEM199", "TMEM230", "TMEM38B", "TMEM43", "TMEM70", "TMF1", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPRKB", "TPX2", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSG101", "TTC19", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNDC15", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBA5", "UBE2N", "UBIAD1", "UBQLN4", "UBR5", "UBTF", "UFC1", "UFSP2", "UGCG", "UGDH", "UGP2", "UMPS", "UNC119", "UNG", "UPF3B", "UQCC2", "UQCRB", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP8", "USP9X", "UTP4", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS13D", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP2", "WDR1", "WDR34", "WDR36", "WDR4", "WDR45B", "WDR5", "WDR73", "WFS1", "WNK1", "WRN", "XPNPEP3", "XPO1", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "YY1", "ZC3H14", "ZCCHC8", "ZMPSTE24", "ZMYM2", "ZNF644"], "leading_proteins": ["ABCB6", "ABHD11", "ABI1", "ADNP", "AFDN", "AKAP12", "AKAP13", "ANXA1", "ARG2", "ARHGEF2", "ARID3B", "ASPSCR1", "BAZ1B", "BCLAF1", "BCR", "BLM", "BPTF", "BRD3", "BRD4", "CADM1", "CC2D1A", "CCAR1", "CCDC22", "CCDC6", "CDC20", "CDC37", "CDC73", "CDH2", "CEP250", "CEP290", "CHAMP1", "CHD7", "CHD8", "CHMP2B", "CNOT3", "COG6", "CRK", "CSNK2B", "CTTN", "CWC27", "DAXX", "DCTN1", "DHFR", "DIAPH1", "DNAJB1", "DNAJB6", "DNAJC2", "DPF2", "DYNC1I2", "EIF4H", "EML4", "ENO2", "EPB41L3", "ETFA", "ETFB", "EWSR1", "EZH2", "EZR", "FEN1", "FIP1L1", "FKBP10", "FLNC", "FMR1", "FUBP1", "GATAD2B", "GCDH", "H4C1*", "HCFC1", "HIP1", "HIP1R", "HIST1H1E", "HMGA1", "HOOK3", "HSPA2", "HSPE1", "HUWE1", "IDH1", "IDH2", "IFT52", "ILF3", "INTS1", "IQCB1", "IRF2BPL", "KDM3B", "KIF5B", "KTN1", "LAMB1", "LAMC1", "LMNA", "MATR3", "MCM3", "MDC1", "MECP2", "MED1", "MKI67", "MTOR", "MYH14", "MYH9", "MYO6", "NBN", "NONO", "NOP10", "NOTCH2", "NPM1", "NSD1", "NUMA1", "NUP214", "PABPC1", "PAF1", "PAFAH1B2", 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file mode 100644 index 0000000000000000000000000000000000000000..5fa79e1a0f7ae641e6864dc08b885d207969e08a --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cc430f7d31b9d9ff9cf4f564b7e4a4f10f067a1aebec748a3d2cef52d1cc8e0e +size 140157 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0a9312eb6dfb93ae89d7c20dd369776994ac7294 --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ed888ac1533b3fd00ec4b1af9326d8fe6cd90b07035ebd5f17b725719c617bc7 +size 97904 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9bca9843dbf39233b6be2ad7a2164fcc8d13b678 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,12 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Actin-binding 34 81 4.185273060808759 2.848235025765256e-05 28.50242718446602 77.73300970873787 -0.9952995302861768 0.4433549972508805 10.031382501204638 7.0257209608212605 1.2964600030364228 0.3696589151561347 1.0 0.2570508466676631 0.3127254475748516 0.1187991738456973 3.9290200885933313e-05 +Calmodulin-binding 21 36 4.117191051314508 3.8351813587356176e-05 10.03640776699029 32.779126213592235 -0.2520849335110281 0.5917094116392749 4.609101876241264 4.7589722327647035 0.8426461576025018 0.3077880283609658 1.0 0.0746572323120207 0.0615174189559832 0.0253281533053532 3.433965928168913e-05 +Repressor 49 127 3.817318068036792 0.0001349102010332 34.45873786407767 115.3131067961165 -0.4658226433075431 0.5740633669441703 13.060194707034563 13.426047826919524 0.999052536384118 0.3409235469179976 1.0 0.1858221436184402 0.0354694666136846 0.0019737519505277 0.015521546663972 +Chromatin regulator 51 97 3.5011356930948088 0.0004632798934076 29.04126213592233 86.34708737864078 -0.7512436046851015 0.4820817863323891 13.599712531200238 14.938170832712968 1.2159678606280355 0.3604236130819139 1.0 0.147057110372491 0.0170335461122621 0.0161040227955586 0.0033789643828803 +Motor protein 20 32 3.308772387839011 0.0009370598353699 10.594660194174756 30.691747572815533 -0.2922630582291772 0.6140754896525568 5.4588727659493275 4.167561958045086 0.8840896638855725 0.3270826794792666 1.0 0.3459346535427879 0.2063668513530253 0.1601360082818727 0.0237928445952987 +Ribosomal protein 53 131 3.0370864354345737 0.0023887694706412 51.866504854368934 120.18932038834951 -1.05133147391923 0.3725452531593897 16.957804412788928 5.935992120172446 1.81153041964891 0.3752694605003574 1.0 0.0085414395311053 3.3033118724142056e-05 2.7631538038503697e-06 1.3642759379229014e-09 +Activator 45 116 2.785157813174183 0.0053501676826346 31.366504854368937 103.85436893203884 -0.5923579597230839 0.5461753930560082 11.612645618867129 12.164453839902244 0.9616851784475308 0.3418011461560053 1.0 0.4153027839706226 0.1858321900475131 0.1917361585449988 0.4623318724514672 +Rotamase 8 24 2.748629223206635 0.0059845039997084 5.225728155339806 21.04368932038835 0.2903016415772153 0.5738010430803833 3.1033990453756255 2.0966996675039535 0.9519067598216118 0.3277712839255824 1.0 0.1330370821365251 0.2489059409173845 0.0006244387843811 0.0003831746340893 +Myosin 7 9 2.7216540487147607 0.0064956102551283 4.315533980582524 9.16019417475728 -0.3228633184750495 0.5220095953205784 2.2213551921343013 1.297334070488979 0.9360094113896 0.3122744843605947 1.0 0.1201219647894398 0.2263045436956677 0.0249818024442509 0.0012998754323988 +DNA-binding 121 242 2.670454969385592 0.0075748531095753 63.34466019417476 223.8131067961165 -0.6004991521595723 0.5562800460977 23.617659297859618 23.56743110299508 1.0964639167234962 0.3575633814496514 1.0 0.0494928068482674 0.3354206632713105 0.4637220452857328 0.5226828356781311 +RNA-binding 142 376 2.344753749077768 0.0190396498867351 107.40776699029126 358.20388349514565 -0.7092617871165062 0.5182701751531077 37.26204422296048 22.39489332536299 1.174880194181004 0.3534939129400228 1.0 0.3291231109048376 0.0126657715312586 0.0001155405085614 2.3014658944941483e-14 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..423b12ecc3b98a5452f19ab1310984e5b8c84a3c --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 97, + "title": "Average number of proteins per term", + "value": 42.5360824742268 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a13ba29d06c6be76a6bcbf2b5c4cc02810be0221 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8421f989d2cfed0af09bf43ee8c2b31019e6ea59 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,34 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Actin-binding 0.4723168540814761 4.1852730608087585 2.8482350257652556e-05 0.0027590142261331 0.0012400419726578 81 Q9Y281,Q9Y2J2,Q14331,Q05682,Q7Z406,P35611,P46939,P50402,P18206,Q6WCQ1,Q9ULV4,P49006,O75146,Q13813,O94832,O43795,P59998,O43491,Q9UM54,O00291,Q9UHB6,Q9Y6W5,O75369,Q9NYL9,P29966,Q01082,P35580,P35579,Q15149,O60610,Q14315,P47755,O00159,P21333 34 +Calmodulin-binding 0.6387675653590326 4.117191051314508 3.8351813587356176e-05 0.0037132858959694 0.0012400419726578 36 O60869,Q05682,Q7Z406,P35611,Q07157,P49006,Q13813,O94832,O43795,Q01844,O43815,Q9UM54,Q86VI3,P29966,Q01082,P35580,P35579,Q15051,P20020,O00159,Q02952 21 +Repressor 0.4899516756736747 3.817318068036791 0.0001349102010332 0.0130019076401219 0.0032715723750572 127 Q96ST3,Q9NWH9,Q6PKG0,Q9NPF5,P51608,O95319,Q14151,P38159,Q9HCD5,Q86YP4,Q15637,Q9HD42,Q5VUA4,P51858,Q15233,Q9UER7,P26599,Q8IX12,O75175,P82094,Q16576,O75446,Q14966,Q12972,Q9BQ70,Q8WXI9,Q6P1N0,P25490,Q9Y2K7,Q01844,P23246,Q15910,Q08170,O14776,Q9NX63,P26358,Q99496,P49750,Q8WXF1,Q13185,Q9HCK8,Q9NYF8,Q96L73,Q15424,Q96PK6,P18615,P14373,O94992,P11142 49 +Chromatin regulator 0.4420791444068309 3.5011356930948088 0.0004632798934076 0.0439533426356757 0.0074896916100905 97 Q9UIF9,Q14527,Q15014,O15047,Q96GM5,O60885,Q9NPF5,Q15059,O75150,Q14839,Q99543,Q92922,Q92785,Q12824,Q9NP66,Q9UER7,Q9P2D1,Q96T23,Q9HAF1,Q16576,Q8IXM2,O43709,Q969G3,Q12830,Q9UBU8,O14497,Q00839,Q9Y2K7,Q15910,Q9UPT9,Q13263,Q92925,Q5VTR2,P26358,Q9NPA8,Q13185,Q9HCK8,Q7LBC6,Q6ZRS2,Q96L73,Q86U86,Q8TAQ2,Q15291,P51610,Q68CP9,Q9P0M6,P25440,O75367,Q9H7B4,Q9Y4B6,Q15906 51 +Motor protein 0.566498863100216 3.308772387839011 0.0009370598353699 0.0869251484631064 0.0129639445094852 32 Q7Z406,Q96Q89,P33176,Q92614,Q02241,P50570,O94832,O43795,Q13409,Q9UM54,Q14807,P35580,Q9Y6G9,P35579,Q9Y496,Q9UQ16,O43237,Q86Y91,O00159,Q8NCM8 20 +Ribosomal protein 0.4409278579588657 3.0370864354345737 0.0023887694706412 0.207044227926411 0.0231710638652202 131 P62913,P83731,Q5T653,Q92665,P26373,P61247,P50914,Q9BYD2,P62917,P84098,Q9NQ50,P62841,P52815,Q9Y3D9,Q02878,Q9Y3B7,P47914,Q8TAE8,P46776,P46778,P62753,Q9BYN8,Q13405,P82912,P61254,P62424,Q96A35,P62750,Q9Y291,P62273,Q9Y2R9,P62081,P62899,Q9P015,P62857,P39019,P46777,Q14197,P46779,P61353,Q8IXM3,P46782,P62263,P83881,P36578,P05387,Q96GC5,Q9BYD3,P82650,P40429,P82673,Q6P1L8,P62847 53 +Activator 0.4126834961047232 2.785157813174183 0.0053501676826346 0.4056931527402334 0.0418112735585499 116 Q14527,Q9NPJ6,O60869,Q9NPF5,Q9HCD5,P38159,Q99543,Q15648,Q8NE71,Q5VUA4,Q92541,O15078,Q15233,P26599,Q8IX12,Q9HAF1,Q71SY5,P17480,Q9Y2W1,Q14966,Q04721,Q9NVC6,Q9NYB0,P53999,P35251,P25490,P23246,Q01664,O14776,Q9UPT9,P26358,Q9NPA8,Q99459,Q8WXF1,Q9P1Z2,O00291,Q9HCK8,Q6ZRS2,Q96L73,Q14498,P17544,Q00059,Q92499,Q9H307,Q5BKZ1 45 +Rotamase 0.5589418437171442 2.748629223206635 0.0059845039997084 0.4413548726574071 0.0418112735585499 24 Q9Y3C6,Q8WUA2,Q13526,Q96AY3,Q9Y237,P30414,Q00688,Q13427 8 +Myosin 0.7790906911990888 2.7216540487147607 0.0064956102551283 0.4685411241291553 0.0418112735585499 9 Q92614,Q9UM54,Q7Z406,P35580,O00159,P35579,O94832 7 +DNA-binding 0.4576000392524404 2.6704549693855917 0.0075748531095753 0.5217194229724775 0.0432212206840478 242 Q9UIF9,P84243,P46013,Q8WYP5,P18754,P54277,Q14151,Q14739,Q14839,P54098,Q96ME7,Q96EK4,P49790,P20585,Q12824,Q96KM6,Q92541,Q9NP66,Q15233,Q9P2D1,P23193,P36776,P82094,P25205,P17480,Q92804,Q14966,Q9BQ70,Q12906,P29692,O14497,P26367,Q9Y2K7,P25490,Q8N1G0,P23246,Q9HCK8,P54132,Q9NYF8,Q96I24,Q8IVW6,P82979,Q5SSJ5,P05204,P14373,Q9NRF9,Q9H307,Q9Y5Q8,Q15906,Q8WVB6,O60869,P11387,P13984,O94842,P51608,Q9Y237,P62805,Q7Z3K3,O75446,P16402,P53999,P05114,P17096,P19338,P26358,Q99459,Q14807,Q92522,O94776,P17544,P26583,Q00059,Q13283,Q15648,P51858,O95983,Q8IXM2,Q96AE4,Q969G3,O75683,P35251,P35269,P16403,P16104,P10412,P07305,Q9Y467,Q9H2P0,Q6ZRS2,Q15424,Q04837,Q9H582,O75717,Q5BKZ1,Q14527,Q8WVM0,P18583,O15347,Q7Z6Z7,Q92945,Q96QC0,Q66K74,Q12972,Q9Y2U8,P06733,P19474,Q6P1N0,Q00839,O95232,Q01664,Q96NC0,Q9NX58,P33991,O75475,P09874,Q86U86,Q9BWH6,Q9UHI6,Q92499,Q9P0M6,O75367 121 +RNA-binding 0.3831920402259259 2.344753749077768 0.0190396498867351 0.8450502009663028 0.0850195091686732 376 Q9NWH9,Q8IXT5,Q6PKG0,P00374,Q14151,O95319,P38159,Q9NZI8,Q15233,P62917,P52272,Q12906,P98175,Q96PU8,P08579,O95104,P06748,P23246,Q96T37,Q08170,P62750,Q9BY77,Q13769,Q7L2E3,Q9H9Y2,Q7L014,Q9UQ35,P82979,Q01130,O75494,P42696,Q7Z417,O60832,P98179,Q96E39,Q15637,Q8TDD1,Q9NR30,P26599,Q14444,Q9H814,Q9NTZ6,Q6PJT7,Q01085,Q8WUA2,P08621,P19338,Q99459,Q76FK4,Q9BTD8,O43818,Q9BQ61,Q13310,Q12904,Q92917,P05455,Q14498,P11940,Q02040,O95793,Q15287,P18615,Q9GZR7,Q9Y3Y2,Q05519,Q6UN15,Q13283,Q9BQ39,Q14331,P62913,P46087,O75179,Q9H7N4,P09012,P78332,Q13243,Q96DE0,Q8IY67,Q8IWZ3,Q9GZT3,O75683,Q9H6R4,Q00341,Q9NXV6,Q9NW13,O95628,Q86XP3,Q01844,Q9NY93,Q8WXF1,Q15056,Q08257,Q86U38,O43432,Q15424,Q96PK6,Q12849,P43243,P49756,Q9P2N5,P55769,Q9UN86,Q8NC51,P52758,Q53F19,P84103,Q01081,Q8WVM0,Q9Y6M1,Q9UKM9,P18583,Q9Y3B4,Q92945,P07814,Q96QC0,Q9H9T3,Q5T8P6,Q12972,Q9UNW9,Q99547,P19474,P61011,P62304,Q00839,P23588,Q9UKV3,Q96I25,Q9HAU5,Q13151,Q9NW64,Q9UJV9,Q07666,P46777,O75821,P09132,Q9Y4C8,P49792,Q53EL6,Q9BZI7,Q92499,P51991,P33240 142 +Growth factor 0.7406271394529766 1.926528063179091 0.0540384712347659 0.9954319902324056 0.1842512327387565 6 Q9Y3E1 1 +rRNA-binding 0.4944879606642136 1.8597509181147696 0.0629207744268103 0.9981706278358684 0.195772637576242 19 Q9H9Y2,P62917,P62750,P62913 4 +Ribonucleoprotein 0.403370798677171 1.848121365247245 0.0645847876540179 0.99846032323347 0.195772637576242 201 O60832,Q9UKM9,P62913,P38159,Q96E39,P83731,Q9NV06,Q5T653,P09012,Q92665,P26373,P61247,P50914,Q9BYD2,P62917,P84098,Q9NQ50,P52272,P62841,P52815,Q9Y3D9,P62314,Q02878,Q9Y3B7,P47914,P08579,Q8TAE8,P61011,P62304,P46776,P46778,Q00839,Q9BYN8,P19474,Q13405,P62753,P82912,P61254,P62424,Q9NPE3,P08621,Q96A35,Q9NRX2,P62750,Q9Y291,Q13151,O43818,Q9Y2R9,P62273,P62081,P62899,Q9P015,P62857,P39019,P46777,Q14197,P46779,P61353,Q8IXM3,P46782,P62263,P83881,P36578,O00566,P05387,Q96GC5,P55769,Q9BYD3,P82650,P40429,P82673,P51991,Q6P1L8,P62847,Q13084 75 +Heparin-binding 0.5990439681274816 1.646212210038991 0.0997200762977743 0.9999624487974522 0.2480217282277977 8 P47914,P51858,P30533 3 +Actin capping 0.6181816045167672 1.531622412744634 0.1256156384676359 0.999997786237556 0.29011230788954 7 Q13813,P47755 2 +Helicase 0.2738759904201189 1.0557795257648015 0.2910689543540889 0.9999999999999968 0.5330315760431666 83 Q9P2D1,Q7L014,Q13283,P25205,Q86XP3,P13984,Q9BQ39,Q9UHI6,Q9GZR7,Q8TDD1,Q9BUQ8,Q9HCK8,P33991,P54132,Q92499,Q9NR30,Q7L2E3,Q6ZRS2 18 +Dioxygenase 0.3740340910578598 0.9264144040621236 0.3542306613359962 1.0 0.6228519964460592 19 Q6P6C2,Q7LBC6,Q9Y2K7 3 +Protein phosphatase inhibitor 0.7417328483330055 0.916156804293032 0.3595846577420547 1.0 0.6228519964460592 3 Q96QC0 1 +Isomerase 0.278147611828377 0.8295105242904687 0.4068155840327765 1.0 0.6923002044066547 65 P13667,Q9Y3C6,Q8WUA2,Q13572,P11387,O60832,Q13526,Q9Y237,Q96AY3,P30101,P30414,Q9H2H8,Q13630,Q13427,Q00688 15 +GTPase activation 0.3106759446657348 0.8014061036902466 0.4228965827462443 1.0 0.7072580780411327 30 Q4KMP7,Q92888,Q8IYB5,A1A4S6,P11274,Q07960,Q9H0H5,P43487,Q15042,Q8N6T3 10 +Guanine-nucleotide releasing factor 0.3049435820546601 0.4603501731810962 0.6452648932384792 1.0 0.8745904910548112 20 Q12802,Q92888,P11274,Q86VX9,O75592,Q5VZ89,Q96N67,Q12979,Q92974 9 +Endonuclease 0.3048180619603482 0.4595399890300229 0.6458464423679116 1.0 0.8745904910548112 20 Q13283,Q14249,Q12972,Q9ULX3,P39748 5 +Chaperone 0.2561797780277076 0.3916076852951396 0.6953481085309077 1.0 0.8957506853261924 113 O00233,Q99543,O75347,Q8N183,Q15785,P61604,Q9Y4L1,Q9UER7,Q16576,P20290,P31689,P25685,P50454,Q16543,O15212,P06748,P0DMV9,Q96EY1,Q13111,Q5F1R6,Q8WXX5,O75190,P54652,O75937,Q9NXW2,Q9NUG6 26 +Serine/threonine-protein kinase 0.2369001338809088 0.3896200690224286 0.696817509737244 1.0 0.8957506853261924 71 Q13464,P11274,Q16513,P51956,O00311,P42345,Q2M2I8,Q13523,O96013,O95747,Q13043,Q99640,Q9H2G2,O75116,P11802,Q9Y5S2 16 +Tyrosine-protein kinase 0.3774834437086343 0.2753422367501522 0.7830533177769714 1.0 0.949460726254172 6 P19525,P41240,Q15375,Q02750,Q9UIG0 5 +Integrin 0.5058533707393016 0.1868404782821559 0.8517857086426974 1.0 1.0 3 P17301 1 +Serine esterase 0.344646799116995 0.1784187497831398 0.8583941253472085 1.0 1.0 6 O14734,Q86TX2,Q9Y305,Q9Y570,P10768 5 +Developmental protein 0.2146369056586277 0.1520870326642924 0.879118291665052 1.0 1.0 92 Q9BY67,Q9UPN4,Q9NR12,O75175,Q9UEE9,Q15007,O60869,Q9H0H5,Q04721,P16949,Q96PU8,Q96N67,O75369,Q9UNS1,Q92974,Q9Y4C8,Q8NCM8,P48681 18 +Methyltransferase 0.2115372767754111 0.1321444827999312 0.8948700122059821 1.0 1.0 51 Q7L2J0,Q8WVM0,Q15910,Q8IY81,P46087,Q9H7B4,Q96L73,Q96FX7 8 +Elongation factor 0.2348715114672546 0.0528411730327174 0.95785845597105 1.0 1.0 11 P49411,P24534,P43897,P26641,Q96RP9,Q9Y450,Q7Z2Z2,Q05639,P29692,P63241 10 +Nuclease 0.1961805158278124 0.0457785178808693 0.9634867811042852 1.0 1.0 37 Q9GZR2,Q13283,Q14249,Q12972,Q9BQ61,Q92499,Q9ULX3,P39748 8 +Thiol protease inhibitor 0.3959543641665504 0.0409782078712576 0.9673132688662072 1.0 1.0 3 Q9NR09 1 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..dcf2b8be9280409dd3fb81d2dff104ed7870c520 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Neuropeptide", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB6", "ABCC1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABR", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "AMFR", "AMPD2", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "ANXA3", "APBB1", "APEH", "APEX1", "APLP2", "APOBEC3C", "APP", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "AS3MT", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATF7", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATPAF2", "ATRX", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAP18", "BAZ1B", "BAZ2A", "BCAT2", "BCKDK", "BCLAF1", "BCR", "BCS1L", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C12orf43", "CABIN1", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX3", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC7", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPU", "CEP131", "CEP290", "CEPT1", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLU", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPS5", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CROT", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DRG1", "DRG2", "DSE", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERMP1", "ERO1A", "ERO1B", "ERP44", "ESD", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "F11R", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM173A", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FNTA", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLT8D1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL3", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS11", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITPK1", "IVD", "JMJD6", "KARS", "KAT7", "KATNA1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KRR1", "KYAT3", "L2HGDH", "LACTB", "LAMP1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMBRD1", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED2", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1S", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MATR3", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFN2", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON1A", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTERF3", "MTF2", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCBP3", "NCEH1", "NCL", "NCOA5", "ND1", "ND5", "NDE1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEK3", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC3", "OTUB1", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAX6", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM7", "PDP1", "PDRG1", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIGG", "PIGK", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R14B", "PPP1R8", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS1", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSMD9", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RFK", "RFX1", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK2", "RIOX2", "RIPK1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP14", "RPP30", "RPP40", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMG1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAST", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAT3", "STAU1", "STK26", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SULT2A1", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAF15", "TALDO1", "TAMM41", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBPL1", "TCEA1", "TCERG1", "TCF25", "TCP1", "TDRKH", "TECR", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TM7SF2", "TMCO1", "TMEM109", "TMEM126B", "TMEM206", "TMEM38B", "TMF1", "TMOD1", "TMOD3", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TSTA3", "TTF2", "TTK", "TTYH3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBLCP1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "UROD", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTRN", "UXS1", "UXT", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VPS72", "VRK1", "VRK2", "WARS", "WARS2", "WASF2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WLS", "WNK1", "WRN", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF2", "YTHDF3", "YY1", "ZADH2", "ZC3H14", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZDHHC13", "ZFR", "ZMAT2", "ZMPSTE24", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687"], "leading_proteins": ["AAK1", "ABCF1", "ABR", "ACIN1", "ACOT1", "ACOT8", "ACOT9", "ADD1", "ADNP", "AHCTF1", "AIMP1", "AKAP12", "AKAP13", "AKAP17A", "ALKBH5", "ANKHD1", "ANKRD17", "ARFGAP1", "ARHGAP1", "ARHGAP10", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARPC4", "ATF7", "ATP2B1", "BAP18", "BAZ1B", "BAZ2A", "BCLAF1", "BCR", "BIRC6", "BLM", "BPTF", "BRD2", "BRD3", "BRD4", "BTF3", "BUD23", "CADM1", "CALCOCO1", "CALD1", "CAPRIN1", "CAPZA2", "CBX3", "CC2D1A", "CCAR1", "CDC37", "CDC42BPB", "CDC5L", "CDC7", "CDK4", "CDKN2AIP", "CELF2", "CEP131", "CEP290", "CFDP1", "CFL2", "CHAF1A", "CHCHD3", "CHD4", "CHD7", "CHD8", "CHMP1A", "CHTF18", "CHTOP", "CNOT3", "CNOT4", "CORO1C", "CRYZ", "CSK", "CSTF2", "DAXX", "DCAF1", "DCAF13", "DDX1", "DDX20", "DDX21", "DDX23", "DDX24", "DDX41", "DDX42", "DDX46", "DDX50", "DDX54", "DDX56", "DENND4C", "DHFR", "DHX30", "DIAPH1", "DKC1", "DMAP1", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJB6", "DNAJC2", "DNAJC21", "DNAJC8", "DNAJC9", "DNM2", "DNM3", "DNMT1", "DOCK7", "DPF2", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EFL1", "EIF2AK2", "EIF3G", "EIF4B", "EIF4G3", "EIF4H", "EIF5A", "ELP3", "EMD", "ENDOG", "ENO1", "ENY2", "EPB41L2", "EPB41L3", "EPHA7", "EPRS", "ESD", "EWSR1", "EZH2", "FEN1", "FIP1L1", "FKBP10", "FKBP3", "FLNA", "FLNB", "FLNC", "FRG1", "FTSJ3", "FUBP1", "FUBP3", "G3BP1", "G3BP2", "GADD45GIP1", "GATAD2A", "GATAD2B", "GFM1", "GPKOW", "GRSF1", "GTF2F1", "GTF2F2", "GTF3C5", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HBS1L", "HCFC1", "HDGF", "HDGFL3", "HDLBP", "HEXIM1", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HLTF", "HMG20A", "HMGA1", "HMGB2", "HMGB3", "HMGN1", "HMGN2", "HNRNPA0", "HNRNPA3", "HNRNPM", "HNRNPU", "HP1BP3", "HSPA1B", "HSPA2", "HSPA8", "HSPE1", "HUWE1", "HYOU1", "IGF2BP1", "IGF2BP2", "ILF3", "IQCB1", "IQGAP3", "ITGA2", "ITPK1", "KDM2A", "KDM3B", "KHDRBS1", "KHSRP", "KIF18B", "KIF20B", "KIF22", "KIF23", "KIF3A", "KIF5B", "LARP1", "LBR", "LEMD3", "LIMA1", "LONP1", "LRPAP1", "LUC7L3", "LYAR", "MAP1S", "MAP2K1", "MARCKS", "MARCKSL1", "MATR3", "MBD3", "MCM3", "MCM4", "MEAF6", "MECP2", "MED1", "MED17", "MED25", "MED4", "MEPCE", "MKI67", "MON1A", "MORF4L1", "MORF4L2", "MPHOSPH10", "MPHOSPH6", "MPRIP", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL17", "MRPL2", "MRPL24", "MRPL28", "MRPL4", "MRPL40", "MRPL41", "MRPL48", "MRPL49", "MRPL58", "MRPL9", "MRPS11", "MRPS22", "MRPS23", "MRPS26", "MRPS31", "MRPS33", "MRPS35", "MRPS7", "MSH3", "MTA2", "MTOR", "MYCBP2", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NCBP3", "NCL", "NCOA5", "NDUFAF2", "NEK3", "NELFE", "NES", "NKTR", "NOB1", "NOL6", "NOL8", "NONO", "NOP10", "NOP2", "NOP9", "NOTCH2", "NOVA2", "NPM1", "NSD1", "NUDT16", "NUFIP2", "NUP153", "OXSR1", "PABPC1", "PABPC4", "PAK4", "PARP1", "PAX6", "PBRM1", "PDCD4", "PDIA3", "PDIA4", "PDLIM7", "PDRG1", "PFDN6", "PHAX", "PIN1", "PIN4", "PKMYT1", "PKN2", "PLEC", "PMS1", "PNN", "POGZ", "POLDIP3", "POLE3", "POLG", "PPIG", "PPIL1", "PPIL3", "PPIL4", "PPME1", "PPP1R10", "PPP1R8", "PRPF4B", "PSIP1", "PSMD9", "PSPC1", "PTBP1", "QKI", "RAB3GAP1", "RACGAP1", "RALY", "RANBP1", "RANBP2", "RAVER1", "RBBP5", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM42", "RBM6", "RBMX", "RBMXL1", "RCC1", "REXO4", "RFC1", "RIDA", "RNF2", "RNF20", "RNF40", "RNPS1", "ROCK1", "ROCK2", "RPAP1", "RPF1", "RPL11", "RPL13", "RPL13A", "RPL14", "RPL19", "RPL21", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL31", "RPL36A", "RPL4", "RPL5", "RPL6", "RPL7A", "RPL8", "RPLP2", "RPS14", "RPS15", "RPS19", "RPS24", "RPS28", "RPS29", "RPS3A", "RPS5", "RPS6", "RPS7", "RRP9", "RSF1", "RTF1", "SAFB", "SAFB2", "SALL2", "SAP30", "SARNP", "SCAF1", "SCAF4", "SERBP1", "SERPINH1", "SETD1A", "SF1", "SF3B6", "SFPQ", "SIN3A", "SLIRP", "SLK", "SLTM", "SMAP1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMYD3", "SNRNP70", "SNRPA", "SNRPB2", "SNRPD1", "SNRPE", "SNU13", "SON", "SPTAN1", "SPTBN1", "SRCAP", "SRP19", "SRP54", "SRRM2", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SSB", "SSBP1", "STAU1", "STK4", "STMN1", "STRN", "SUB1", "SURF6", "TAF15", "TBC1D10B", "TBCA", "TCEA1", "TCERG1", "TCF25", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "THAP11", "THOC5", "THRAP3", "TIAL1", "TIMELESS", "TJP1", "TMF1", "TMOD3", "TOMM34", "TOP1", "TOX4", "TRIM21", "TRIM27", "TRIM28", "TRIR", "TRMT61A", "TSFM", "TSTA3", "TUFM", "U2AF1", "UBTF", "UPF2", "UPF3B", "USP22", "UTRN", "VCL", "VPS72", "WASF2", "WDHD1", "WTAP", "YLPM1", "YY1", "ZC3H14", "ZMAT2", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file 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0000000000000000000000000000000000000000..d174ab3b902ab1ea0bb49927b3ad990d8b0c51f6 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7000ee4d7194358779b6c1c437527cb523f6dfeb259d3e748ccbd47bc01ae049 +size 117782 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..598c79a05e4ff5e922071e32b827e721b719c3c3 --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted intracellular proteins 1271 3333 inf 0.0 1052.9126213592233 2930.233009708738 -5.248196350890207 0.108353777008802 367.4824441165934 294.4528727150831 7.24167812525605 0.3049463326237019 0.8975088269741103 0.0298297310310066 0.001493448613749 5.574162267644739e-06 1.391110257761943e-07 +Plasma proteins 300 1365 4.510722380049127 6.460723065870866e-06 344.36893203883494 1267.8446601941748 -2.063867871440958 0.2726358151952098 106.00045706910636 75.63812765385998 2.3956561829748337 0.3901747881772643 1.0 0.0047132395956151 3.419843100652229e-05 2.0462158937596746e-06 9.627813879248448e-18 +Transcription factors 42 61 4.077719537238618 4.547957998690677e-05 18.12621359223301 54.89320388349515 -0.5323757742992309 0.5413960687288952 7.990199836681589 8.85937890540299 0.9539652174072304 0.3331905427774767 1.0 0.5376676772470171 0.7857819228930857 0.993852087293582 0.999980110807328 +Ribosomal proteins 55 138 2.982333829647837 0.0028605989068417 54.21601941747573 126.59708737864078 -1.1013645810576873 0.3672949560938939 17.688909247563995 6.332440078033074 1.7905145664594482 0.3696976543931279 1.0 0.0096570635022048 4.374996504758194e-05 9.444215669275313e-07 1.6211677674036351e-10 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d2462490d479c98321eabf54f71d35608a3337a7 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 20, + "title": "Average number of proteins per term", + "value": 573.6 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ffc45c89dde0a759567da7c21b6f2f59c81c5c0f --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f405a270918819436b4878e79e23a153a9e09472 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Plasma proteins 0.2515322233198768 4.510722380049127 6.460723065870866e-06 0.0001292065308457 1.8459208759633905e-05 1365 Q96ST3,Q9Y3C6,Q9UPN4,P46013,Q9UKX7,Q12834,Q6PKG0,Q9UKY7,P31948,O00233,O60271,Q14151,O75380,P38159,Q05682,Q7Z406,P51784,P20585,P83731,Q8NE71,Q96KM6,Q9P2E9,Q92974,P48735,P07942,Q15233,Q15758,Q9P2D1,P62917,P84098,Q9NQ50,P20290,O43752,Q09666,Q13564,Q12802,P82094,Q14966,P48634,P52272,P25205,P17480,O43852,Q13523,Q12906,Q15942,Q9BSJ2,Q9UIJ7,P61088,O14737,P08579,P43487,Q92878,P48681,O00764,O15212,Q9Y2K7,O95104,O43290,O94832,P25490,P23246,Q96T37,O14776,P62424,P27816,Q14980,Q9H4M9,Q9UNZ2,P62750,Q15075,Q9H1B7,Q9BPU6,P78316,Q9HCK8,P62899,Q8NBS9,P26572,O75874,O60664,P54132,Q01082,Q15149,Q9NYF8,Q96L73,Q92733,Q7L014,Q13428,Q9P260,O43395,O14802,Q9UDY2,P82979,Q13442,Q9UQ35,Q01130,P17980,P55196,P20020,Q14315,P40429,P53990,P55072,Q9UQB8,Q9P0J1,Q9BTC0,Q9Y281,Q9BY67,Q13464,Q15014,Q8WWM7,P04083,Q14249,O43837,O60832,O94842,Q9Y237,P53597,Q99543,Q86YP4,Q15637,Q15437,P30511,Q8TDD1,Q92922,P61604,Q00688,Q9NR30,Q96HC4,Q9Y4L1,Q9UIG0,Q8N6T3,P26599,Q7Z3K3,P12270,O75400,P18669,P29083,Q9Y2W1,Q04721,Q14141,Q8WXI9,Q9BV73,P19022,Q16881,Q5JRA6,Q5JTV8,Q7Z3B4,P53999,P35658,Q8IWJ2,Q9NZZ3,Q9Y490,P13807,P33908,O95169,O95757,Q15910,P84095,P08621,P19338,Q13308,P49750,Q99459,P26358,P11047,P28838,Q7LBC6,Q92522,Q07960,P35579,Q14498,P11940,P26583,P14314,O95793,O14678,Q9H7Z3,Q14978,Q05519,P47755,Q8N3R9,Q15459,Q02952,P13667,P07197,Q13283,Q9Y2J2,Q9NPF5,Q9BQ39,P62913,P46087,O75179,Q92785,Q15648,Q92665,P51858,P78332,P46939,P26373,P18206,O60493,P50914,Q13435,Q96AE4,Q92614,Q86UP2,Q14241,Q12830,O75683,P09496,P62314,Q00341,Q9BX68,Q86XP3,O14745,Q01844,P16403,P16104,P07305,O43491,Q9UM54,Q15056,Q13185,Q08257,P08397,O60841,O75369,P29966,P35580,P39019,Q15019,Q9Y383,Q86U38,Q15424,Q14677,P11166,O00311,P43243,P49756,P54652,Q9UKS6,Q9H2G2,Q8NC51,P21333,Q14683,Q9Y6M1,Q16513,P36543,P18583,P10586,P09104,O15347,Q92945,Q15398,Q13427,Q03252,P39748,P33176,Q9NP79,Q92888,Q5T8P6,P15311,P50454,P80723,Q9UMX0,Q14008,Q14247,O15213,P59998,O95232,Q14203,Q9UQE7,Q9UKV3,Q9HAU5,Q86VI3,Q13151,P09417,O95785,P02545,O14964,P30101,P46777,P58107,Q9Y4C8,O75475,P29401,P09874,P18859,P05387,P42345,P49916,P51610,Q9UHI6,Q9H1E3,Q92499,P51991,P33240,Q13112,Q96RQ1 300 +Transcription factors 0.5343930804963178 4.077719537238618 4.547957998690677e-05 0.0009091987124395 0.0001136989499672 61 Q9UPT8,Q9NPF5,O94842,Q99543,Q86YP4,Q96ME7,Q92922,Q96EK4,Q9UBC1,Q96KM6,Q9NP66,Q15233,Q7Z3K3,P17480,Q969G3,Q9BQ70,Q8WXI9,O95628,O14497,Q9Y2K7,P25490,P26367,Q8N1G0,P23246,Q01664,Q9Y467,P17096,P26358,Q8WXF1,Q99459,Q9NX58,O95785,Q9H2P0,O94776,Q8IVW6,P17544,Q86U86,Q00059,Q8TAQ2,Q9H582,Q68CP9,Q13330 42 +Ribosomal proteins 0.4424010596692751 2.982333829647837 0.0028605989068417 0.0556835672202439 0.0063568864596483 138 P62913,P83731,Q5T653,Q92665,P26373,P61247,P50914,Q9BYD2,P62917,P84098,Q9NQ50,P62841,P52815,Q9Y3D9,Q02878,Q9Y3B7,Q9UHA3,P47914,Q8TAE8,P46776,P46778,P62753,Q9BYN8,Q13405,P82912,P61254,P62424,Q96A35,P62750,Q9Y291,P62273,Q9Y2R9,P62081,P62899,Q9P015,P62857,P39019,P46777,Q14197,P46779,P61353,Q8IXM3,P46782,P62263,P83881,P36578,P05387,Q96GC5,P55769,Q9BYD3,P82650,P40429,P82673,Q6P1L8,P62847 55 +Cancer-related genes 0.3004909670024606 0.7720325081081728 0.4400951739834569 0.9999908317970804 0.5867935653112758 397 Q96ST3,Q9UBW7,P46013,Q12834,P00374,Q15059,P38159,Q14676,P48735,P07942,Q15233,Q9P2D1,P82094,P25205,P62841,Q12906,P25685,P98175,Q96PU8,P61088,O43290,P06748,P23246,Q96T37,Q14980,Q9HCK8,P54132,O75874,P55036,Q15149,Q9NYF8,Q96L73,Q92733,Q9UDY2,Q13442,Q01130,P55196,P14373,P04083,Q8IZP0,O60885,P11387,P51608,Q99543,P18887,P61604,P40818,P62805,Q9UER7,Q8IX12,P12270,O75175,O60934,P68402,Q04721,Q16543,Q16881,Q86VS8,Q9BZE9,P35658,Q15910,P11274,P17096,P11047,Q9ULW0,P35579,P61353,O60610,P11940,P78540,P67870,P22314,Q9H7B4,Q6UN15,Q02952,Q15648,P78332,Q96AE4,Q86UP2,P16949,Q01844,O43815,Q15056,Q15019,Q9H2P0,Q5VU43,P11166,P54652,Q14683,P09104,Q7Z6Z7,P39748,P33176,Q13526,O75146,P15311,Q14247,Q14203,Q9UQE7,O00291,P02545,P46777,O75475,P09874,P42345,Q9HC35 106 +Citric acid cycle related proteins 0.3098539091272514 0.6642516403240774 0.5065292670447672 0.9999992667906278 0.5967645309409627 25 P48735 1 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bef136e1bec7dc68656092c5ac4aa1a23d39ef01 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOC1", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIP1", "BRIX1", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf76", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf198", "C1orf35", "C2CD2", "C2CD2L", "C2CD5", "C2orf49", "C3orf58", "C5orf24", "C5orf51", "C8orf33", "C9orf64", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCDC97", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPH", "CENPK", "CENPP", "CENPU", "CENPV", "CEP131", "CEP170", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD2", "COMMD6", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERICH1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM160B2", "FAM162A", "FAM173A", "FAM177A1", "FAM207A", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNBP1", "FNBP4", "FNDC3A", "FNTA", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC1", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH11", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KNOP1", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC45", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYRM2", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTF2", "MTFP1", "MTFR1", "MTG1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKBIL1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAWR", "PAX6", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD11", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PXMP4", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "R3HCC1", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN2", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCOC", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLAIN2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG8", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TCP11L1", "TCTN3", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THADA", "THAP11", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM131", "TMEM14C", "TMEM161A", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMA21", "VMP1", "VPS13A", "VPS13D", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR89", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WRAP73", "WRN", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIPF3", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFPL1", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZNF687", "ZNHIT2", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABCD4", "ABCF1", "ABI1", "ACIN1", "ADNP", "AFDN", "AHNAK", "AK3", "AKAP12", "AKAP13", "ANKRD17", "ANXA1", "ARFGAP1", "ARG2", "ARHGAP1", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARPC4", "ASPSCR1", "ATF7", "ATP2B1", "ATP5J", "ATP6V1E1", "ATXN2L", "BAIAP2", "BASP1", "BAZ1B", "BCLAF1", "BCR", "BLM", "BPTF", "BRD3", "BRD4", "BTF3", "CADM1", "CALD1", "CALU", "CAPZA2", "CBX3", "CCAR1", "CDC20", "CDC37", "CDC5L", "CDC7", "CDH2", "CDV3", "CEP131", "CEP250", "CFL2", "CHAF1B", "CHD7", "CHD8", "CHMP5", "CKAP5", "CLINT1", "CLTA", "CNOT3", "CNOT4", "CRYZ", "CSNK2B", "CSTF2", "CTTN", "DAXX", "DCTN1", "DDX1", "DDX20", "DDX21", "DDX42", "DDX46", "DDX50", "DDX54", "DHFR", "DIAPH1", "DIDO1", "DKC1", "DLGAP5", "DMAP1", "DNAJB1", "DNAJC2", "DNMT1", "DPF2", "DPYSL5", "EEA1", "EHD1", "EIF4H", "EIF5B", "ELOA", "EML4", "ENDOG", "ENO2", "EPB41L2", "EPB41L3", "EPPK1", "ERGIC2", "EWSR1", "EZH2", "EZR", "FEN1", "FIP1L1", "FKBP3", "FLNA", "FLNB", "FLNC", "FUBP1", "G3BP1", "GADD45GIP1", "GATAD2A", "GATAD2B", "GCC2", "GTF2E1", "GYS1", "H1F0", "H1FX", "H2AFX", "H4C1*", "HCFC1", "HDGF", "HDLBP", "HGS", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HLA-F", "HMBS", "HMG20A", "HMGA1", "HMGB2", "HMGB3", "HNRNPA0", "HNRNPA3", "HNRNPM", "HOOK3", "HSPA2", "HSPA4L", "HSPE1", "HUWE1", "HYOU1", "IDH1", "IDH2", "IDH3B", "IGF2BP2", "ILF3", "IQGAP3", "IRF2BPL", "IST1", "KDM2A", "KDM3B", "KHSRP", "KIAA1468", "KIF5B", "KTN1", "LAMB1", "LAMC1", "LAP3", "LARP1", "LIG3", "LMNA", "LMNB2", "LUC7L2", "LUC7L3", "LYAR", "MAN1A1", "MAP4", "MARCKS", "MATR3", "MCM3", "MDC1", "MECP2", "MED1", "MGAT1", "MIA3", "MKI67", "MORF4L2", "MPP5", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL2", "MRPL24", "MRPL4", "MRPL40", "MRPL41", "MRPL48", "MRPL49", "MRPL58", "MRPL9", "MRPS11", "MRPS22", "MRPS23", "MRPS26", "MRPS31", "MRPS33", "MRPS35", "MRPS7", "MSH3", "MTA1", "MTA2", "MTOR", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1D", "MYO6", "NAE1", "NBN", "NCL", "NDUFB8", "NDUFS6", 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0000000000000000000000000000000000000000..a35390bc04c777c0524651c43157ed7721d2699a --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cf3e8d07228e375fa048a46955dce27c02834934a720e8a2df0d46dc107d699e +size 90619 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..81613e36fa31975414135d434a86179cf55a16e0 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,8 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Nucleoplasm 363 1373 5.824232783252351 5.737555830405275e-09 317.2645631067961 1230.2936893203882 -1.674965813079066 0.2416580447075201 89.8022120435567 131.39482729463506 2.523508597527768 0.3580410225372186 1.0 0.7973147027579321 0.7483031006625003 0.3220284915591496 0.4702106867160162 +Nucleoli rim 21 58 4.054649673656929 5.020949343870207e-05 26.29126213592233 54.949029126213595 -1.3176841375773052 0.3549913093662085 8.899253888177155 3.655667767234105 1.3959886459077675 0.3583848194117569 1.0 0.4392448907866976 0.3188748568193547 0.0005865597950624 4.867773031821959e-05 +Mitotic chromosome 19 40 3.882821568082044 0.0001032513358909 18.98543689320388 35.75728155339806 -1.3453226058379633 0.3101380062519321 6.50353015067777 1.776141883039992 1.344647045652705 0.3392315165259217 1.0 0.2486824788491954 0.1106573079891401 1.271360736672949e-07 3.146725552876313e-06 +Nuclear speckles 52 135 3.828563189042218 0.0001288935398708 38.25485436893204 123.91747572815534 -0.7100521127875458 0.5319283642145574 14.444423142868942 13.476984531958683 1.0076072203290958 0.335396104447401 1.0 0.8125963139005776 0.0462157640444196 7.487741188236771e-05 4.4078833817648327e-10 +Centriolar satellite 13 35 2.304234789711971 0.0212094672781117 6.354368932038835 28.046116504854368 0.5330334825095895 0.5754639941794782 3.863025543447266 4.860211896177677 0.8074973811315178 0.3370904262689401 1.0 0.4364495014109603 0.683314509064718 0.0655141513844624 0.0108058362651867 +Focal adhesion sites 10 31 2.1787233414936384 0.0293522266955341 6.264563106796117 27.364077669902912 0.2615680943966604 0.640618977052225 3.6431084765940094 3.1857496524893976 0.758529337646141 0.3146129005339539 1.0 0.3394178268581344 0.1992060977406469 0.0169427644497248 0.0516175810284066 +Actin filaments 15 50 2.119110265832689 0.0340811493472259 11.95873786407767 47.19174757281554 -0.3952214715557959 0.579028391445234 5.992774480975272 4.29547400713696 0.8391895673084235 0.321367677055939 1.0 0.1621145077252613 0.1749719564938417 0.1526447368571805 0.0271717554679962 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cdfed35a3efe8afc9d6c8e7905f09c31b3695384 --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3630, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 167.3030303030303 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f1137a6c43b7c5645df17943657f050689c4a6b6 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C057/C057_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..09486d7bbe71d4e500012d145c53271e49f1d722 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,22 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nucleoplasm 0.2736857331106331 5.824232783252351 5.7375558304052755e-09 1.8933932505485434e-07 1.8933934243637409e-07 1373 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363 +Nucleoli rim 0.5404291419807168 4.054649673656929 5.020949343870207e-05 0.0016555828893994 0.0008284566417386 58 P46013,Q9Y3B9,O75683,Q1ED39,Q9UHA3,Q6PJT7,Q14008,Q01844,P06748,P16403,Q8IY81,P19338,Q9H6F5,Q86VI3,Q9H3R5,P46777,Q92522,O00566,Q8NEF9,Q5QJE6,Q96RQ1 21 +Mitotic chromosome 0.592204726944059 3.882821568082044 0.0001032513358909 0.0034016711627668 0.0010633717039348 40 Q6PK04,P46013,Q9Y237,Q8TBB5,Q9Y3B9,O75683,Q8IY81,P19338,Q9H6F5,Q86VI3,Q76FK4,Q99848,Q9H3R5,O00566,Q9UMY1,Q9BRT6,Q14692,P42696,Q5QJE6 19 +Nuclear speckles 0.496492735549127 3.828563189042218 0.0001288935398708 0.0042447265362553 0.0010633717039348 135 Q8N3X1,O75152,P18583,Q13123,Q14157,Q13427,P78332,Q9UNF0,Q15233,Q7Z6E9,Q9P013,Q13435,Q5T8P6,Q9Y2W1,Q14241,Q13523,Q12972,P98175,Q9Y2V7,P08579,Q6PJT7,O43290,Q86XP3,P16104,P10412,O95232,O95400,Q08170,Q9ULR0,Q9UPT9,P49750,Q9BY77,P04920,P02545,Q9NYF8,Q92733,Q7L014,Q14498,Q96PK6,P05387,Q9UQ35,Q15007,P82979,O75298,Q5SSJ5,P49756,Q05519,P25440,Q53F19,O60828,Q15459,Q15906 52 +Centriolar satellite 0.4498505642316207 2.304234789711971 0.0212094672781117 0.5070962972538418 0.1166520700296148 35 O14745,Q14498,Q9UPN4,Q9Y448,Q86VS8,Q9Y5K6,O60271,Q9Y6A5,Q5SVZ6,Q15398,Q96QE3,P33176,Q9Y490 13 +Focal adhesion sites 0.4484942079593151 2.1787233414936384 0.0293522266955341 0.6258593765366955 0.1249642142731618 31 Q9Y490,O60888,Q15149,Q9ULX3,Q15942,Q9UHB6,Q14676,Q13136,Q96HC4,P18206 10 +Actin filaments 0.388331125671263 2.119110265832689 0.0340811493472259 0.6815500555210336 0.1249642142731618 50 P07305,Q9NR12,Q6WCQ1,P49006,Q9P0K7,Q9HCD5,O14974,Q05682,Q15942,Q9UHB6,O75369,P21333,P35580,Q15019,P35579 15 +Cytoplasmic bodies 0.4895855482942485 1.768567202239106 0.0769661281391513 0.9288488271285932 0.2308983844174541 18 P08579,Q6P2E9,P78332,Q9BY77 4 +Mitotic spindle 0.3975193842937565 1.6260411068221678 0.1039409109795781 0.9732631998634996 0.2858375051938399 28 Q9Y448,Q8WWK9,Q14203,Q15051,P05387,O00311,Q02241,Q9Y6A5 8 +Nuclear bodies 0.3391291926320576 1.420143143107082 0.1555660122845359 0.9962271610808024 0.385703591419137 130 Q9NWH9,Q16513,Q15059,Q14151,P20585,Q14676,Q9UER7,Q96QC0,Q9HAF1,P41214,Q96JM3,P61956,Q9NQS7,Q99590,Q8WW12,P07305,Q99496,Q15056,Q13185,O75874,P35579,Q6ZRS2,P18615,Q9UHI6,O00159,Q7Z417 26 +Cytokinetic bridge 0.3661448142376381 1.3929601991296727 0.1636318266626641 0.9972513626956708 0.385703591419137 33 Q9UPN4,Q15051,O00311,Q02878,Q15019,Q96QE3 6 +Midbody 0.4355513036355863 1.3199729758461267 0.1868440408124785 0.99891423204716 0.4110568897874527 17 Q15424,Q99661,P28838,O95785,Q9NQS7,Q96Q89,Q7Z7K6,Q9NZZ3,Q9UN37 9 +Midbody ring 0.6547710516954264 1.260870190974308 0.2073556195971992 0.99953270976708 0.4276709654192235 5 O95319,Q96JM3 2 +Microtubules 0.3051656239033847 1.1422770744906323 0.2533388674719634 0.999934975506925 0.4644545903652663 61 P13807,Q13409,Q13564,Q9UPN4,Q8WWK9,Q14203,Q14498,Q15051,P51956,P27816,P13984,Q9HC35,P31689,O75347,Q02878,Q13813,Q9NZZ3 17 +Cell Junctions 0.2934751056080826 0.9440843218209354 0.3451265604057743 0.9999991425803564 0.5994303417573974 55 Q9BY67,Q8IZP0,Q9Y2J2,Q9BW91,P35221,O00151,Q9NV06,P46940,Q07157,Q4VCS5,P19022,Q6IAN0,P35269,Q7L2J0,O43491,O60245,Q9UDY2,Q16625,P55196,O96013 20 +Lipid droplets 0.4039998622680588 0.7041938613589989 0.4813120533858575 0.9999999996092462 0.7179537656713294 10 P08397,O60664 2 +Nucleoli 0.3368005305219542 0.6400375412130388 0.5221481932155123 0.999999999973898 0.7179537656713294 306 Q9GZR2,Q9Y3C6,Q9UKY7,Q9P2D1,P62917,P84098,Q9NQ50,Q9NZM5,Q12906,Q9NVU7,P47914,Q13409,Q8IY81,P62424,Q9H6F5,Q99848,P78316,Q9H9Y2,P05204,P14373,P40429,P42696,Q5VZL5,Q9NRF9,Q5QJE6,Q6PK04,Q9BSC4,O94842,Q9Y237,Q8TBB5,Q8TDD1,Q9H2H8,O43709,P68402,Q15050,Q9UHA3,Q6PJT7,P53999,P61254,P17096,P19338,Q76FK4,Q99640,Q9NSI2,Q9H501,Q92522,Q5JTH9,P61353,Q5F1R6,P26583,O00566,Q15291,Q9UMY1,Q9GZR7,Q969S3,Q9H4L5,Q14692,Q9BQ39,Q9NUQ8,P46087,Q9Y2S6,O75347,Q32P28,Q92665,P11802,P26373,P61247,Q13243,O75683,Q9NW13,Q9BVJ6,Q86U38,Q9BUQ8,O95347,Q8NBT2,O15347,Q9Y3C1,Q9NV06,Q53T59,P39748,Q15435,Q1ED39,Q99547,Q14008,O15213,P46777,Q9Y4C8,Q96T60,P09874,Q9H1E3,Q9BZI7,Q9BRT6 92 +Nucleoli fibrillar center 0.2578931238848601 0.5824210668285269 0.5602830948127839 0.9999999999983225 0.7395736851528748 66 Q9P016,Q9BRX2,O60832,P11387,Q15233,P17480,P61088,Q6P1N0,P46778,P25490,Q8WXF1,Q969X6,P62750,Q96EB6,Q9C0J8,Q7L014,Q13428,Q14978,Q8N1G4,Q5M775 20 +Plasma membrane 0.2940852156541498 0.1790924708851972 0.8578650937950232 1.0 0.9587334018158352 345 Q8WUJ1,Q8TD16,Q9UKY7,P31948,O00233,Q9NZM3,Q05682,Q9UNF0,Q15758,Q09666,Q567U6,P48634,Q15942,P27816,Q9H4M9,Q9UNZ2,Q9H7E9,Q9UHB6,Q96CT7,Q14197,Q96L73,Q8WXX5,Q9UDY2,Q13442,Q2M2I8,Q16625,P55196,Q9Y366,P20020,Q14315,P30414,Q9UQB8,O00159,Q9Y281,P04083,Q8IZP0,P53597,Q9NZL9,Q96HC4,O60888,P68402,Q9Y5K6,Q04721,P19022,Q9BZE9,Q9Y490,O43795,P11274,P11047,P04920,Q96D71,Q9H910,Q96CN9,Q5JTH9,P35579,O60610,Q8NFH5,P83881,Q9NP58,Q9BWU0,Q8N3R9,O75845,Q02952,Q8IYB5,Q9Y2J2,P35611,P46940,A0FGR8,P46939,Q9Y448,Q6IAN0,O14745,Q12846,O43491,Q96CN5,Q96IZ0,Q9NT62,Q9UJZ1,Q9Y6W5,O60841,O75369,Q8N8S7,P29966,Q15019,O60245,P04406,P11166,Q9H223,Q96SB4,Q9BU76,Q9UKS6,Q9H2G2,O75691,P21333,Q9BSR8,Q16513,P55011,Q9Y305,P09104,Q8TBC4,P35221,O00151,P26038,P49593,Q92888,O75146,P15311,Q9NV70,Q9UJU6,P80723,Q6P1N0,Q14008,Q14247,Q9UKV3,O96013 115 +Endosomes 0.2769622755132975 0.1616571882400668 0.8715758198325776 1.0 0.9587334018158352 12 P09496,O14964 2 +Centrosome 0.1961607055929217 0.0803855145450427 0.9359306473385908 1.0 0.9963132697475322 78 Q8WWK9,Q99661,Q16513,Q8TBC4,Q96CS2,Q9NV06,Q9HD42,O15078,Q13564,O75147,Q8WYA6,Q9BV73,Q9H981,Q9BSJ2,P41223,Q14008,O95757,Q9P270,Q96CN5,Q9Y6G9,P55081,O43237 22 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d9adadb181121511e4451d39a654523754a0aa60 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL6IP6", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC2", "ARPC3", "ARRB2", "ARV1", "ARVCF", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GALT1", "B4GALT3", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIP1", "BRIX1", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf76", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf198", "C1orf35", "C2CD2", "C2CD2L", "C2CD5", "C2orf49", "C5orf24", "C5orf51", "C8orf33", "C9orf64", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC127", "CCDC137", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCDC97", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC123", "CDC20", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPH", "CENPP", "CENPU", "CENPV", "CEP131", "CEP170", "CEP250", "CEP290", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN6", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG5", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ3", "COQ8A", "CORO1B", "COTL1", "COX1", "COX14", "COX15", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERICH1", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM160B2", "FAM162A", "FAM173A", "FAM177A1", "FAM207A", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNBP1", "FNBP4", "FNDC3A", "FNTA", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNS", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGPS1", "GHITM", "GID4", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR2", "GOT1", "GPAA1", "GPAM", "GPATCH11", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC2", "HEXA", "HEXIM1", "HGH1", "HGS", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "IAH1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFIT5", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRGQ", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KNOP1", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLPH", "LMAN1", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC45", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYRM2", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED2", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD3", "MFSD8", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRE11", "MRFAP1", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTERF3", "MTF2", "MTFP1", "MTFR1", "MTG1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK3", "NELFA", "NELFCD", "NELFE", "NEMF", "NES", "NFATC2IP", "NFKBIL1", "NFS1", "NFU1", "NHLRC2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAWR", "PAX6", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH7", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE4DIP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREP", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PXMP4", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "R3HCC1", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RFX1", "RHBDD2", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN2", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2C", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCLY", "SCML2", "SCO2", "SCOC", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLAIN2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG8", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPDL1", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP11L1", "TCTN3", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THADA", "THAP11", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM131", "TMEM161A", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMOD3", "TMX1", "TMX2", "TMX4", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TWISTNB", "TXLNA", "TXLNG", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS36", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR74", "WDR77", "WDR82", "WDR89", "WIZ", "WLS", "WNK1", "WRN", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIPF3", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFPL1", "ZFR", "ZFYVE16", "ZMAT2", "ZMYM1", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["AAK1", "ABCB6", "ABCF3", "ABI1", "ACIN1", "ACOT9", "ACTR8", "ADD1", "ADNP", "AFDN", "AGL", "AHNAK", "AKAP12", "ALKBH5", "AMOT", "ANKRD17", "ANXA1", "ARHGAP10", "ARHGEF1", "ARID3B", "ARL6IP4", "ASPSCR1", "ATAD5", "ATF7", "ATG3", "ATP2B1", "ATP6V1E1", "BAIAP2", "BAP18", "BASP1", "BAZ1B", "BCLAF1", "BCR", "BICD2", "BLM", "BMS1", "BPTF", "BRD2", "BRD3", "BRD4", "BUD23", "BUD31", "C1orf35", "C2orf49", "C8orf33", "CADM1", "CALD1", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCDC124", "CCDC137", "CCDC86", "CCDC93", "CCDC94", "CD2AP", "CD2BP2", "CDC20", "CDC5L", "CDC7", "CDH2", "CDK4", "CDKN2AIP", "CDV3", "CELF2", "CENPH", "CENPV", "CEP131", "CEP250", "CEP290", "CFDP1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD7", "CHD8", "CHMP1A", "CHMP5", "CHTF18", "CIZ1", "CKAP2", "CKAP5", "CLINT1", "CLTA", "CNOT11", "COG6", "COPS7A", "COPS8", "CSTF1", "CSTF2", "CTNNA1", "CTNNBL1", "CTTN", "CUTA", "CWC15", "CWC27", "CYB5D2", "DAXX", "DBNL", "DCAF13", "DCAF8", "DCTN1", "DDX1", "DDX20", "DDX21", "DDX23", "DDX24", "DDX42", "DDX46", "DDX50", "DDX54", "DHRS7B", "DIAPH1", "DIDO1", "DKC1", "DLGAP5", "DMAP1", "DNAJA1", "DNAJB1", "DNAJB6", "DNAJC21", "DNAJC8", "DNAJC9", "DNMT1", "DNPH1", "DNTTIP2", "DPF2", "DPYSL5", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "EBNA1BP2", "EDC4", "EDF1", "EHD1", "EHD4", "EIF2D", "EIF4H", "EIF5B", "ELOA", "EML4", "ENAH", "ENO2", "ENY2", "EPB41L2", "EPB41L3", "ERGIC2", "ERP29", "ESF1", "ESS2", "ESYT2", "EWSR1", "EXOC1", "EZH2", "EZR", "FAM207A", "FEN1", "FIP1L1", "FLNA", "FLNB", "FLNC", "FNBP4", "FTSJ3", "FUBP1", "FUBP3", "GADD45GIP1", "GAPDH", "GATAD2A", "GATAD2B", "GCC1", "GCC2", "GCFC2", "GFM1", "GINS3", "GLDC", "GPKOW", "GTF2E1", "GTF2F1", "GTF2F2", "GTF3C2", "GTF3C5", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY2", "H4C1*", "HAUS1", "HCFC1", "HDGF", "HDGFL2", "HDGFL3", "HELLS", "HEXIM1", "HGS", "HIP1R", "HIST1H1C", "HIST1H1E", "HMBS", "HMG20A", "HMGA1", "HMGB2", "HMGB3", "HMGN1", "HMGN2", "HNRNPA0", "HNRNPA3", "HNRNPM", "HOOK3", "HP1BP3", "HS1BP3", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HUWE1", "IDH1", "IFT52", "IK", "ILF3", "INCENP", "INPP4A", "INTS1", "IQCB1", "IQGAP1", "IQGAP3", "IRF2BPL", "ISY1", "ITSN2", "JPT2", "KDELC2", "KDM2A", "KDM3B", "KHSRP", "KIAA1468", "KIF20B", "KIF23", "KIF2C", "KIF3A", "KIF5B", "KLHDC4", "KNOP1", "KNSTRN", "LAMC1", "LANCL2", "LAP3", "LARP1", "LIG3", "LIMA1", "LLPH", "LMNA", "LRRC45", "LRRC47", "LTV1", "LUC7L2", "LUC7L3", "MAD1L1", "MAP4", "MARCKS", "MARCKSL1", "MAT2B", "MATR3", "MBD3", "MCM3", "MCM4", "MCUB", "MDC1", "MEAF6", "MECP2", "MED1", "MED25", "MEPCE", "MFAP1", "MKI67", "MORF4L2", "MPHOSPH10", "MPHOSPH6", "MPP5", "MPRIP", "MRFAP1", "MRPL2", "MRPL40", "MRPL58", "MRPS31", "MSH3", "MSN", "MTA2", "MYCBP2", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO6", "NAE1", "NANS", "NBN", "NCBP3", "NCL", "NCOA5", "NEK3", "NELFE", "NFATC2IP", "NFKBIL1", "NKTR", "NOB1", "NOL10", "NOL6", "NOL7", "NOL8", "NOLC1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP9", "NOTCH2", "NPM1", "NRDE2", "NSD1", "NSFL1C", "NUCKS1", "NUDT16", "NUDT9", "NUFIP2", "NUMA1", "NUP35", "NUP50", "NUP54", "OBSL1", "OCLN", "ORC2", "OSBP", "OSBPL3", "P3H1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAK2", "PAK4", "PARP1", "PAWR", "PCDH7", "PCNP", "PDAP1", "PDCD5", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDXK", "PELO", "PFDN6", "PGAM1", "PHAX", "PHF10", "PHF14", "PHF3", "PIN1", "PIN4", "PKMYT1", "PKN2", "PLEC", "PLIN3", "PLOD1", "PNKP", "POGZ", "POLDIP3", "POLE3", "POLR1C", "POLR3A", "PPFIA1", "PPIG", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PQBP1", "PRCC", "PRPF3", "PRPF4B", "PRRC2A", "PSIP1", "PSMC3", "PSMD4", "PSMD9", "PSPC1", "PTBP1", "QKI", "RAB3GAP1", "RACGAP1", "RAD50", "RAI14", "RAVER1", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM19", "RBM25", "RBM26", "RBM28", "RBM3", "RBM34", "RBM39", "RBM42", "RBM6", "RBMX", "RBMXL1", "REPS1", "REXO4", "RNASEH2C", "RNF2", "RNF40", "RNPS1", "RPF1", "RPL13", "RPL13A", "RPL19", "RPL21", "RPL23A", "RPL26", "RPL27", "RPL29", "RPL36A", "RPL5", "RPL6", "RPL7A", "RPL8", "RPLP2", "RPRD1B", "RPS19", "RPS3A", "RRP12", "RRP15", "RRP9", "RRS1", "RSF1", "RSL24D1", "RTF1", "RTN2", "SAFB", "SAFB2", "SALL2", "SAP30", "SAP30BP", "SARNP", "SART1", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCOC", "SDAD1", "SEC13", "SEC24B", "SEPT2", "SF1", "SF3A1", "SF3B2", "SFPQ", "SIN3A", "SIRT1", "SLAIN2", "SLC12A2", "SLC1A5", "SLC2A1", "SLC4A1AP", "SLC4A2", "SLC9A3R1", "SLK", "SLTM", "SMAP1", "SMARCC1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMYD3", "SNAP29", "SNRNP70", "SNRPA", "SNRPB2", "SNW1", "SON", "SPAG9", "SPC24", "SPECC1", "SPTAN1", "SRCAP", "SRFBP1", "SRPK1", "SRRM2", "SRSF10", "SRSF11", "SRSF2", "SRSF4", "SRSF5", "SSB", "STIP1", "STK4", "STOML2", "STRN", "STX4", "STX6", "SUB1", "SUCLG1", "SUMO2", "SURF6", "TACC3", "TADA3", "TBCA", "TCERG1", "TCOF1", "TERF2IP", "TFAP4", "THOC5", "THRAP3", "THYN1", "TIAL1", "TIMELESS", "TJP1", "TJP2", "TKT", "TLN1", "TMA7", "TMEM192", "TNFAIP8", "TOP1", "TOX4", "TPX2", "TRIM27", "TRIR", "TSR1", "TSTA3", "TUBGCP2", "TXNRD1", "UBA1", "UBA2", "UBA3", "UBAP2L", "UBE2N", "UBQLN1", "UBTF", "UBXN1", "UCK2", "UPF3B", "USP11", "USP22", "UTP14A", "UTP20", "UTP4", "UTRN", "VCL", "VCP", "VPS4A", "VPS72", "VTA1", "WASF2", "WBP11", "WDR33", "WDR46", "WIZ", "WTAP", "XRCC1", "YIPF4", "YLPM1", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H4", "ZMYM1", "ZMYM2", "ZMYM4", "ZNF318", "ZNF326", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZYX"]} \ No newline at end of file