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Hur elavl1 binds and stabilizes mrna 0.9066259581103988 2.443735716728443 0.0145360704192665 0.999999999025194 1.0 5 P39687 1
Metabolism of cofactors 0.903401624577922 2.4308874394222393 0.0150618929617047 0.9999999995424182 1.0 5 P00374 1
Glycogen synthesis 0.8941534299541736 2.393929122930538 0.0166689695676249 0.9999999999547584 1.0 5 Q96G03,Q04446 2
Mastl facilitates mitotic progression 0.858501440922188 2.2499812110010997 0.0244501380478676 0.9999999999999994 1.0 5 P30153,P30154,Q96GX5,P06493 4
Signaling by egfr in cancer 0.8234957717831926 2.1063859850672646 0.0351708376911177 1.0 1.0 5 P62993,P07900 2
Constitutive signaling by ligand responsive egfr cancer variants 0.8234957717831926 2.1063859850672646 0.0351708376911177 1.0 1.0 5 P62993,P07900 2
Constitutive signaling by egfrviii 0.8234957717831926 2.1063859850672646 0.0351708376911177 1.0 1.0 5 P62993,P07900 2
Phosphorylation of emi1 0.8425064326695737 2.014986808886101 0.0439060312427219 1.0 1.0 4 P06493,Q12834 2
G1 s specific transcription 0.8151305874047178 2.0067534206362674 0.0447759247848258 1.0 1.0 10 P31350,P00374,P06493 3
Recycling of eif2 gdp 0.7900807381776257 1.9984802344400352 0.0456646207133419 1.0 1.0 7 Q13144,Q9UI10,P05198,Q9NR50,P20042,P49770 6
Met receptor recycling 0.7973391798925108 1.99766332713908 0.0457531726235131 1.0 1.0 5 P46108 1
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.7759488634553151 1.9716526181100669 0.0486492760683927 1.0 1.0 6 P30153,P30154 2
Uptake and function of diphtheria toxin 0.828548532587265 1.9585332930705324 0.0501674683581123 1.0 1.0 4 P07900,P08238 2
Prolonged erk activation events 0.7680759932742862 1.9062473302907763 0.0566181241524548 1.0 1.0 7 P27361,P46108,P36507,P31946,P28482 5
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.8083500912616725 1.8763162005771088 0.0606118737600902 1.0 1.0 4 P30154 1
Negative feedback regulation of mapk pathway 0.7986171132238415 1.836485245668647 0.0662859222473422 1.0 1.0 4 P27361,P28482,P36507 3
Fceri mediated ca 2 mobilization 0.783222648223829 1.7732152338594236 0.076193048693852 1.0 1.0 4 P62993 1
Negative regulation of fgfr2 signaling 0.7289778387609595 1.7724606329906494 0.0763181245606952 1.0 1.0 6 P30153,P62993,P27361 3
Negative regulation of fgfr4 signaling 0.7289778387609595 1.7724606329906494 0.0763181245606952 1.0 1.0 6 P30153,P62993,P27361 3
Negative regulation of fgfr1 signaling 0.7289778387609595 1.7724606329906494 0.0763181245606952 1.0 1.0 6 P30153,P62993,P27361 3
Negative regulation of fgfr3 signaling 0.7289778387609595 1.7724606329906494 0.0763181245606952 1.0 1.0 6 P30153,P62993,P27361 3
Spry regulation of fgf signaling 0.7289778387609595 1.7724606329906494 0.0763181245606952 1.0 1.0 6 P30153,P62993,P27361 3
Transcriptional activation of mitochondrial biogenesis 0.7881527775639017 1.7715365884126588 0.0764715139168608 1.0 1.0 14 P48735 1
Tp53 regulates transcription of cell death genes 0.7434140782945786 1.7698857246827555 0.0767461793616046 1.0 1.0 5 Q9Y255 1
Signalling to erks 0.7541547471382912 1.7525705787921886 0.0796757451201763 1.0 1.0 10 P62993,P27361,P46108,P36507,P31946,P28482,P11233 7
Small interfering rna sirna biogenesis 0.7712064986356071 1.7236105132036414 0.0847781793447277 1.0 1.0 4 Q99598,O75569 2
Activation of nima kinases nek9 nek6 nek7 0.7688642572473289 1.7139199295121978 0.0865434323237726 1.0 1.0 4 P06493 1
Raf independent mapk1 3 activation 0.7156872643120447 1.6835023139410648 0.0922778918093447 1.0 1.0 7 P28482,P36507,P06493,P27361 4
Signalling to ras 0.8624341163730999 1.681918829249271 0.0925845809315983 1.0 1.0 3 P11233 1
Suppression of apoptosis 0.7207492795389013 1.672821059872907 0.0943625276977728 1.0 1.0 5 P23246,P28482,P49840,P27361 4
Oncogene induced senescence 0.704428271633266 1.6351073723763514 0.1020265409613521 1.0 1.0 7 P11802,P28482,Q00534,P27361 4
Dna replication initiation 0.693179824490716 1.6183367782411608 0.1055900387497423 1.0 1.0 6 Q9NR33,P49642 2
Pp2a mediated dephosphorylation of key metabolic factors 0.8444796795011198 1.613548882346013 0.106625312221342 1.0 1.0 3 P30154 1
Signaling by fgfr1 0.69699330614091 1.6030597396159645 0.1089214655086352 1.0 1.0 7 P30153,P62993,P27361 3
Signaling by fgfr3 0.69699330614091 1.6030597396159645 0.1089214655086352 1.0 1.0 7 P30153,P62993,P27361 3
Signaling by fgfr4 0.69699330614091 1.6030597396159645 0.1089214655086352 1.0 1.0 7 P30153,P62993,P27361 3
Mapk3 erk1 activation 0.7404937834524378 1.5960308324242778 0.1104819097318086 1.0 1.0 4 P06493,P27361 2
Bmal1 clock npas2 activates circadian gene expression 0.7365906259689429 1.5797436466510055 0.1141655857438834 1.0 1.0 4 P43490 1
Aryl hydrocarbon receptor signalling 0.8350967604885144 1.5777178508489496 0.1146304434753928 1.0 1.0 3 P08238 1
Trafficking of myristoylated proteins to the cilium 0.8317635211432199 1.5649738543954634 0.117589039941258 1.0 1.0 3 A6NIH7 1
Phenylalanine and tyrosine metabolism 0.7277729748726441 1.5428952150522084 0.1228562019912407 1.0 1.0 4 O43708 1
Cyclin a b1 b2 associated events during g2 m transition 0.7027616232379947 1.5343273111127205 0.1249491500817359 1.0 1.0 10 P30153,P30154,P06493,P63151 4
Runx2 regulates bone development 0.6734177098130054 1.5325281495030654 0.1253921566472684 1.0 1.0 6 Q13951,Q96PK6,P27361 3
Budding and maturation of hiv virion 0.6924408540103946 1.520913673514916 0.1282815021504255 1.0 1.0 9 Q9NZZ3,Q9UN37,Q99816,Q96FZ7,Q9Y3E7,Q9NP79,Q9UQN3,Q9H9H4 8
Erks are inactivated 0.6772138573847251 1.517488011722007 0.1291435179875579 1.0 1.0 7 P51452,P30153,P30154,P27361 4
Response of eif2ak1 hri to heme deficiency 0.8191244239631353 1.5165850409457085 0.1293714845518692 1.0 1.0 3 P08243,P05198 2
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.7162565132748444 1.494665633216142 0.1350017276657651 1.0 1.0 4 P11802,Q00534 2
Diseases of mismatch repair mmr 0.8130760368663634 1.493395484759252 0.1353336941930472 1.0 1.0 3 P20585,P52701 2
Regulation of runx1 expression and activity 0.7140005973546856 1.485205732874881 0.1374893338455813 1.0 1.0 4 Q13951,Q00534 2
Antigen activates b cell receptor bcr leading to generation of second messengers 0.7130227309145315 1.4811040013011556 0.138578861794566 1.0 1.0 4 P62993 1
Enos activation 0.8084051771583339 1.4754743640178731 0.1400850555446531 1.0 1.0 3 P07900 1
Ncam signaling for neurite out growth 0.6574663781779264 1.462957175824934 0.1434790973252835 1.0 1.0 6 P28482,P62993,P27361 3
Heme degradation 0.7085571776759303 1.4623642886811212 0.1436414099929026 1.0 1.0 4 P30043,P53004 2
Activation of ampk downstream of nmdars 0.6571374427970492 1.461520022534118 0.143872784822149 1.0 1.0 6 Q9BVA1,P68371,Q13885,P54619 4
Cytosolic sulfonation of small molecules 0.6640257429879854 1.460210381909042 0.1442322629034802 1.0 1.0 7 O95340,Q06520,O43252 3
Met activates rap1 and rac1 0.656237555349531 1.457587841966458 0.1449541828332843 1.0 1.0 6 P46108 1
Lipophagy 0.8024193548387145 1.4524931095093048 0.1463645437161997 1.0 1.0 3 O60664,P54619 2
Signal attenuation 0.8012672811059947 1.4480682141611616 0.1475979740494328 1.0 1.0 3 P62993,P27361 2
Cyclin d associated events in g1 0.6894017473041193 1.4467406305876234 0.1479695802353577 1.0 1.0 11 P24941,P30153,Q00534,Q13309,P11802,P63151,P30154 7
Endosomal sorting complex required for transport escrt 0.6866176670636713 1.4348421030431593 0.1513320971295377 1.0 1.0 11 Q9NZZ3,Q9UN37,Q99816,O14964,Q96FZ7,Q9BRG1,Q9Y3E7,Q9NP79,Q9UQN3 9
Sema3a pak dependent axon repulsion 0.658103940309281 1.434442599593342 0.1514459983649434 1.0 1.0 7 Q13177,P07900,P08238 3
Mtorc1 mediated signalling 0.6721494767643754 1.433544185852802 0.1517023809637716 1.0 1.0 9 P42345,P31946,P23588,Q04637,P62942 5
Pyrimidine salvage 0.7957532855005575 1.4268829349802978 0.1536136404693684 1.0 1.0 3 Q08623 1
Late endosomal microautophagy 0.6759018759018478 1.4191956074949654 0.1558419962145283 1.0 1.0 10 O95613,Q99816,Q96FZ7,P11142,O60664,Q9Y3E7,P08670,Q9UQN3,Q9H9H4 9
Inlb mediated entry of listeria monocytogenes into host cell 0.6470697677482506 1.417490368664379 0.1563396082909731 1.0 1.0 6 P62993 1
Bbsome mediated cargo targeting to cilium 0.6470510234001732 1.3862803184880443 0.1656613242446649 1.0 1.0 7 P17987,P50991,P78371 3
Dna damage reversal 0.6504733784840675 1.368079231276996 0.171287276853242 1.0 1.0 5 Q9H1I8,Q6P6C2,Q8N9N2 3
E2f mediated regulation of dna replication 0.6733136502952929 1.3481112612616937 0.1776225999676781 1.0 1.0 12 P30153,P30154,P06493,P14635 4
Rora activates gene expression 0.6809582326470313 1.3462957324153624 0.178207161593048 1.0 1.0 4 P50416,Q9BZK7 2
Map2k and mapk activation 0.6727524224522415 1.3457177134677818 0.1783935715390057 1.0 1.0 12 P30086,P27361,P10398,P36507,P31946,P41240,P28482,Q02750,P18206 9
Pyroptosis 0.6367767631343224 1.341448123360422 0.1797750020420394 1.0 1.0 7 P09429,Q9UQN3,P42574,Q96FZ7 4
Gap junction assembly 0.6431655453208794 1.3361728753064055 0.1814927747120012 1.0 1.0 5 Q9BVA1,P68371,Q13885 3
Transport of connexons to the plasma membrane 0.6431655453208794 1.3361728753064055 0.1814927747120012 1.0 1.0 5 Q9BVA1,P68371,Q13885 3
Caspase activation via extrinsic apoptotic signalling pathway 0.6755978104292741 1.323718498014126 0.1855965526669654 1.0 1.0 4 Q13546,Q9UKG1,P42574 3
Condensation of prometaphase chromosomes 0.6495230907654959 1.305711347302982 0.1916507376528353 1.0 1.0 10 P19784,P14635,Q15021,P06493,O95347,Q15003 6
Sumo is transferred from e1 to e2 ube2i ubc9 0.7574884792626783 1.2796874576360322 0.200655077440041 1.0 1.0 3 P61956,Q9UBE0 2
Processing and activation of sumo 0.7574884792626783 1.2796874576360322 0.200655077440041 1.0 1.0 3 P61956,Q9UBE0 2
Sumo is conjugated to e1 uba2 sae1 0.7574884792626783 1.2796874576360322 0.200655077440041 1.0 1.0 3 P61956,Q9UBE0 2
Runx2 regulates osteoblast differentiation 0.6273181099123459 1.2669321683045474 0.2051795452285856 1.0 1.0 5 Q13951,P27361 2
Post chaperonin tubulin folding pathway 0.6361105871244049 1.2479497633328178 0.2120494550325804 1.0 1.0 10 Q9BVA1,P68371,Q99426,P36404,O75347,Q13885 6
Nucleotide salvage 0.621063129076264 1.242544394693654 0.214035771348763 1.0 1.0 8 Q08623,P00492,Q9BZX2,P07741 4
Fceri mediated mapk activation 0.620827484510778 1.2415197995668263 0.2144137885200465 1.0 1.0 8 Q13177,P28482,P62993,P27361 4
Polb dependent long patch base excision repair 0.6112529638031468 1.2299410836588198 0.2187191681023472 1.0 1.0 7 Q9NX46,Q9UGN5,P18858,P39748 4
Signaling by mras complex mutants 0.7422028826565871 1.2209053791309288 0.2221218475854876 1.0 1.0 3 P10398 1
Folding of actin by cct tric 0.6153243964273354 1.2175944317690046 0.2233781314686505 1.0 1.0 8 P17987,P50991,P78371,P49368 4
Gab1 signalosome 0.7397838935737742 1.2116098075786168 0.2256617785159724 1.0 1.0 3 P62993 1
Smooth muscle contraction 0.6318030658003959 1.2000464175612446 0.2301213136592832 1.0 1.0 11 P60660,P06753,Q13177,P04083,Q05682,P67936 6
Mismatch repair 0.6295466551065164 1.19038358342077 0.2338956624434605 1.0 1.0 11 P52701,P15927,P43246,P18858,Q9UQ84,P20585 6
Glycogen metabolism 0.6226072360861643 1.1898210340184678 0.2341167405045547 1.0 1.0 10 P46020,Q04446,Q96G03 3
Platelet aggregation plug formation 0.6078426755775541 1.1818481239998038 0.2372659688292757 1.0 1.0 5 P62993,P46108 2
Integrin signaling 0.6078426755775541 1.1818481239998038 0.2372659688292757 1.0 1.0 5 P62993,P46108 2
Heme signaling 0.5930250064554938 1.1803450151480652 0.2378630212648509 1.0 1.0 6 Q86X55,Q9BZK7,Q96EB6 3
Golgi cisternae pericentriolar stack reorganization 0.627118091077186 1.1799861770166191 0.2380057127184274 1.0 1.0 11 P27361,Q9H0U4,P14635,P28482,P06493 5
Mapk1 erk2 activation 0.7300033968265321 1.1740541509980618 0.2403733364080922 1.0 1.0 3 P36507 1
Signaling by moderate kinase activity braf mutants 0.6451350166912679 1.1704407325880863 0.2418236518381997 1.0 1.0 14 P30086,P27361,P10398,P36507,P31946,P41240,P28482,Q7Z569,Q02750,P18206 10
Synthesis of pc 0.595548589286047 1.1613565427190222 0.245496934026784 1.0 1.0 7 P35790 1
Met promotes cell motility 0.5989128767177682 1.1463024310969847 0.2516700373722091 1.0 1.0 8 P46108 1
E2f enabled inhibition of pre replication complex formation 0.5845372371463562 1.143112627814207 0.2529918319778683 1.0 1.0 6 P06493,P14635 2
Cd28 dependent vav1 pathway 0.5987269987561097 1.1420724417765589 0.2534239093478274 1.0 1.0 5 Q13177,P62993 2
Purine salvage 0.5978534896342607 1.138263702128655 0.2550103858897288 1.0 1.0 5 P00491,P00492,P07741 3
Nicotinamide salvaging 0.711659732486299 1.10378846559388 0.2696849094906399 1.0 1.0 3 P43490 1
Hsf1 activation 0.6212150883329162 1.0976879021728978 0.2723407942232347 1.0 1.0 13 P07900,P08238,P15927,Q02790,P62258 5
Nicotinate metabolism 0.6215878353053217 1.0964726144500014 0.2728720014751422 1.0 1.0 4 P43490 1
Interferon gamma signaling 0.6057737066283287 1.088780273717637 0.2762507925515507 1.0 1.0 11 Q12899,P19474 2
Attenuation phase 0.605709184671412 1.0885051974761064 0.2763721433420338 1.0 1.0 11 P07900,P08238,P0DMV9,P25685,P11142,Q02790 6
Circadian clock 0.6019861204416151 1.0726408392840294 0.2834322937186246 1.0 1.0 11 Q96EB6,Q86X55,P50416,Q9BZK7,P43490 5
Unwinding of dna 0.5831847961392185 1.049273714538809 0.2940521601916179 1.0 1.0 9 P25205,P49736,Q14566,Q9BRT9,P33991 5
Sealing of the nuclear envelope ne by escrt iii 0.6024683708237811 1.0465007196464762 0.2953299128428752 1.0 1.0 12 Q9BVA1,P68371,Q9UN37,P53990,Q96FZ7,Q9Y3E7,Q13885,Q9UQN3 8
Aggrephagy 0.6276236991408656 1.0416176061433189 0.2975890026645269 1.0 1.0 16 Q9BVA1,P68371,Q9Y6G9,O43237,P07900,Q13885,O95613,Q13409,P08670,P61088 10
Uptake and function of anthrax toxins 0.6912442396313447 1.0259805224941303 0.3049007651093491 1.0 1.0 3 P36507,Q02750 2
Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0.8902965735675221 1.0127065479231232 0.3112003493125606 1.0 1.0 2 Q13951 1
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.5990098331759568 1.0021583412513253 0.3162671242747195 1.0 1.0 4 Q9BZK7 1
Wnt mediated activation of dvl 0.5983716117796526 0.9995035411519724 0.3175508245160743 1.0 1.0 4 P19784,P68400 2
Cell extracellular matrix interactions 0.5648735743379527 0.9991645398913716 0.3177149905324932 1.0 1.0 8 Q13418 1
Rhobtb3 atpase cycle 0.6840437788018513 0.998671703653878 0.3179537524474565 1.0 1.0 3 O60664,O14964 2
Signaling by ntrk3 trkc 0.6836669832589806 0.997244901507522 0.3186456509124489 1.0 1.0 3 P62993 1
Nuclear signaling by erbb4 0.5957653051097263 0.988669738336246 0.3228247533948123 1.0 1.0 4 P16949 1
Formation of tubulin folding intermediates by cct tric 0.5952149201915118 0.9883111292643084 0.323000296537054 1.0 1.0 13 Q99832,P68371,P50991,Q9BVA1,P40227,P17987,P78371,P49368,Q9BUF5,Q13885 10
Nef mediated downregulation of mhc class i complex cell surface expression 0.5628242074927909 0.986214120973579 0.3240280513222378 1.0 1.0 5 P56377,Q9BXS5,P04439,O43747 4
Darpp 32 events 0.5608263934025118 0.9817806349311416 0.3262079303710661 1.0 1.0 8 P30153,P30154 2
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.5805033248641246 0.9814884146083384 0.3263519448042529 1.0 1.0 11 P27348,P31946,P14635,O96017,P61981,P62258,P06493,P63104 8
Signaling by erbb4 0.5501796815141861 0.964402570567759 0.3348441339672332 1.0 1.0 7 P61201,P16949 2
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.5557232762516241 0.9599068963763776 0.3371020750277826 1.0 1.0 8 P27361,P50750,Q9UPN9,P28482,P09874 5
Signaling by ntrk2 trkb 0.5566197686809602 0.9594846958162015 0.3373146258447537 1.0 1.0 5 P63000,P62993 2
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.6153502204578993 0.9381196757538904 0.3481829113750005 1.0 1.0 18 Q99832,P68371,O15212,P50991,Q9BVA1,P17987,P78371,P49368,Q9BUF5,Q9UHV9,Q9NQP4,Q13885,P61758 13
Raf activation 0.582893837689402 0.9369012516292922 0.3488093553260425 1.0 1.0 13 P30153,P10398,P36507,P31946,Q7Z569,P30154 6
Piwi interacting rna pirna biogenesis 0.5683141449459594 0.9301536393022696 0.3522915417205388 1.0 1.0 11 Q8N2A8 1
Translation of replicase and assembly of the replication transcription complex 0.5305462759821499 0.9081992200216312 0.3637729761202006 1.0 1.0 6 Q9Y3E7,Q9UQN3,Q96FZ7 3
Negative regulation of met activity 0.5434675624900581 0.9076143195718592 0.3640820260827577 1.0 1.0 8 P62993,P40818 2
G2 m dna replication checkpoint 0.8577598617909661 0.9006560236784623 0.3677712373123181 1.0 1.0 2 P06493 1
Signal transduction by l1 0.5600895538522357 0.8957185847971492 0.3704030819565795 1.0 1.0 11 P19784,P27361,P36507,P28482,Q02750 5
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.539694280300233 0.8915919094553203 0.3726117082485309 1.0 1.0 8 Q86X55,P06493,P14635 3
Interconversion of nucleotide di and triphosphates 0.5971510514970296 0.8901782746758653 0.3733701682249986 1.0 1.0 17 P31350,P32321,P04818,P00390,Q16881,Q9NRF8,Q9H773,P15531,P17812 9
Signaling by erbb2 in cancer 0.5395492418377933 0.8864081699025567 0.3753976183155454 1.0 1.0 5 P62993,P07900 2
Signaling by erbb2 ecd mutants 0.5395492418377933 0.8864081699025567 0.3753976183155454 1.0 1.0 5 P62993,P07900 2
Activation of the ap 1 family of transcription factors 0.6539143357153238 0.8854420144244028 0.3759182806786725 1.0 1.0 3 P27361 1
Signaling by csf3 g csf 0.5366441873101891 0.8786700193590702 0.3795802188062533 1.0 1.0 8 P40763,P62993,Q15369,Q93034,P42224 5
Regulation of runx3 expression and activity 0.7234726652703998 0.8760966972009461 0.3809774681336733 1.0 1.0 38 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,Q13951,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 22
Purine ribonucleoside monophosphate biosynthesis 0.5471861471861507 0.8687247466747978 0.3849977025009501 1.0 1.0 10 P31939,O15067,P30520,Q06203,P30566,P49915,P12268,P20839,P22102 9
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.67252849443002 0.867518778093079 0.3856578275336537 1.0 1.0 30 P61163,Q9Y6G9,P07900,P08238,O60884,P0DMV9,P11142,Q9UJW0,Q13885,O75935,P31948,P52907,Q13561,P25685,Q02790,Q9BVA1,O43237,P68371,P54652,Q13409,P47756,Q13451,Q14203,P31689 24
Carboxyterminal post translational modifications of tubulin 0.5259110142598749 0.8606097341423923 0.3894530229205513 1.0 1.0 7 Q9BVA1,P68371,Q9UPW5,Q13885 4
Smad2 smad3 smad4 heterotrimer regulates transcription 0.5644605704772852 0.859727524424581 0.3899392585820402 1.0 1.0 4 P28482,P27361 2
Degradation of axin 0.7186150954389903 0.8581880482633084 0.3907886344991298 1.0 1.0 38 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Ngf stimulated transcription 0.6460328270764737 0.8561662766921699 0.3919058131000714 1.0 1.0 3 Q00535 1
Inactivation of csf3 g csf signaling 0.5172383253970398 0.851236914479534 0.3946377607417324 1.0 1.0 6 P40763,P42224,Q15369 3
Nade modulates death signalling 0.8419234091563528 0.846994479867337 0.3969981983049009 1.0 1.0 2 P62258 1
Negative regulation of mapk pathway 0.5737064123500479 0.8465806634792803 0.3972288955948202 1.0 1.0 15 P30153,P27361,P10398,P36507,P31946,P28482,Q7Z569,P30154,Q02750 9
Cytochrome c mediated apoptotic response 0.5295109174900922 0.8438227207273897 0.3987684770986097 1.0 1.0 5 P42574,P27361 2
Constitutive signaling by overexpressed erbb2 0.558730337525827 0.8364185952760379 0.4029194550343098 1.0 1.0 4 P62993,P07900 2
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.6403333832382543 0.8351027644351972 0.4036598503336266 1.0 1.0 3 P63000 1
Hsf1 dependent transactivation 0.5643679192353188 0.8343644938829102 0.4040756189455097 1.0 1.0 14 P07900,P08238,P42345,P0DMV9,P25685,P11142,Q02790 7
Glycogen storage diseases 0.6399529013335304 0.8336999956702489 0.4044500605784416 1.0 1.0 3 Q04446 1
Platelet sensitization by ldl 0.5174481857445421 0.8248262243194064 0.4094702559734835 1.0 1.0 7 P30154 1
Synthesis of udp n acetyl glucosamine 0.552866609046385 0.8126821630986923 0.4164003104125602 1.0 1.0 4 Q06210,O95394,Q16222 3
Advanced glycosylation endproduct receptor signaling 0.5271868570679996 0.8120596498902641 0.4167574048378717 1.0 1.0 9 P52907,P09429,P17931,P27361 4
Nr1h2 and nr1h3 mediated signaling 0.5043174434303912 0.7964957656038315 0.4257439357216905 1.0 1.0 6 Q9BZK7,Q9HCE1 2
Nucleotide biosynthesis 0.5476603119584129 0.7921900866869334 0.4282498479966663 1.0 1.0 13 P31939,O15067,P30520,P27708,Q06203,P30566,P49915,Q05682,P20839,P12268,P11172,P22102 12
Degradation of dvl 0.7091792061224473 0.7806876304764838 0.4349862375113917 1.0 1.0 40 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Signaling by hippo 0.5069077229760939 0.780628790054898 0.4350208537912428 1.0 1.0 7 P62258,P42574 2
Activation of rac1 0.4999790395760642 0.7782609974786817 0.4364151635596425 1.0 1.0 6 P63000,O96013,Q13177 3
Regulation of ras by gaps 0.7081654330841483 0.7770622390209349 0.4371220510447307 1.0 1.0 40 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Rap1 signalling 0.6243470208123035 0.7765614767952329 0.4374175371164011 1.0 1.0 3 P31946 1
Nuclear events stimulated by alk signaling in cancer 0.530645351593585 0.7741941334356099 0.4388159970238705 1.0 1.0 11 P40763,Q9HC35,P27361,P62753,P63208,P28482,P33176 7
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.5179335901920592 0.7737866674400501 0.4390569581353505 1.0 1.0 9 P61086,Q16763 2
Cd163 mediating an anti inflammatory response 0.6232718894009277 0.7726555442112994 0.439726262969264 1.0 1.0 3 P78536,P35579 2
Stabilization of p53 0.705510340237465 0.7675863014108862 0.4427330033176107 1.0 1.0 40 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Transcriptional regulation of granulopoiesis 0.5097356127766186 0.7660462929769503 0.4436487576767169 1.0 1.0 8 P40763,P24941,P11802,Q03164,Q13951 5
Glycogen breakdown glycogenolysis 0.4967894130113255 0.7649060794885469 0.4443274735040203 1.0 1.0 6 P46020,Q96G03 2
Condensation of prophase chromosomes 0.5337213139445812 0.7612194989481724 0.4465259735844964 1.0 1.0 12 Q01105,P06493,O95347,P14635 4
Uptake and actions of bacterial toxins 0.508458549828646 0.7607727367164522 0.4467928211637515 1.0 1.0 8 Q16881,P36507,P07900,P08238 4
Asymmetric localization of pcp proteins 0.7029320963257502 0.7584115334172092 0.4482046554976437 1.0 1.0 40 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Arms mediated activation 0.8119781169018219 0.7475349670992558 0.4547407038207922 1.0 1.0 2 P46108 1
Listeria monocytogenes entry into host cells 0.5051000249144032 0.746939509863365 0.4551000752479408 1.0 1.0 8 P62993 1
Early phase of hiv life cycle 0.5112228817408845 0.7462596994276252 0.4555105511167703 1.0 1.0 9 Q13426,P17096,P18858,P39748 4
Infection with mycobacterium tuberculosis 0.5403474835621808 0.7378674901812249 0.4605949761104688 1.0 1.0 14 P27361,O14964,P14373,P52294,P28482,P49840,Q9UI12,Q9H267,P23246 9
Response of mtb to phagocytosis 0.5403474835621808 0.7378674901812249 0.4605949761104688 1.0 1.0 14 P27361,O14964,P14373,P52294,P28482,P49840,Q9UI12,Q9H267,P23246 9
Metabolism of polyamines 0.6964730685534979 0.7355475698866496 0.4620060801174754 1.0 1.0 40 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Apoptosis induced dna fragmentation 0.5134823910891587 0.7299832689376953 0.4654004116067274 1.0 1.0 10 P42574,P26583,P10412,P52294,P09429 5
Caspase mediated cleavage of cytoskeletal proteins 0.4879426016533814 0.7281104923966949 0.4665459514591674 1.0 1.0 6 P42574,P08670,P35611 3
Cellular response to hypoxia 0.7108784491019298 0.7247452496911347 0.4686083296645305 1.0 1.0 43 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,Q13617,O43242,P20618,Q9NWT6,P61289,P25788,P25786,P25787,O00487,P62191 23
Regulation of bach1 activity 0.6099320142067082 0.7245568062431872 0.4687239656315778 1.0 1.0 3 Q13309 1
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.500819951141203 0.7242200575535293 0.4689306465752183 1.0 1.0 5 Q96JJ3,P46108 2
Auf1 hnrnp d0 binds and destabilizes mrna 0.7032687028053662 0.7184845370577452 0.4724585787944502 1.0 1.0 42 O14818,Q14103,P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P11940,P62195,Q06323,P62333,P11142,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,Q04637,O00487,P62191 27
Signaling by activin 0.80103656780881 0.711966262526908 0.476485667844142 1.0 1.0 2 P27361 1
Signaling by nodal 0.80103656780881 0.711966262526908 0.476485667844142 1.0 1.0 2 P27361 1
Scf skp2 mediated degradation of p27 p21 0.7009008806914155 0.7102611521634861 0.477542205366334 1.0 1.0 42 Q13309,P28070,O00231,O00233,P11802,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 23
Galactose catabolism 0.8001727613014769 0.7091778972484316 0.4782140877622614 1.0 1.0 2 Q96G03 1
G1 s dna damage checkpoints 0.6940976449395301 0.7068041588815731 0.4796881897237999 1.0 1.0 41 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.5252062010153169 0.7024562210518075 0.4823946945461641 1.0 1.0 13 Q99832,P19784,P68400,P50991,P40227,P17987,P78371,P49368,P67870 9
Dscam interactions 0.6013824884792695 0.6941150864778819 0.4876100381922166 1.0 1.0 3 P63000,Q16539 2
Rho gtpases activate paks 0.5169162583147769 0.6940809456435149 0.4876314473074328 1.0 1.0 12 P63000,P60660,Q13177,P35579,Q7Z406,Q14247 6
Transcriptional regulation by runx3 0.7019829342364255 0.6940254800686948 0.4876662298729703 1.0 1.0 43 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,Q13951,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 22
Cdt1 association with the cdc6 orc origin complex 0.6954581353492859 0.6914570720472208 0.4892783489761341 1.0 1.0 42 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Dag and ip3 signaling 0.4974418259206796 0.6904189879415001 0.489930739294359 1.0 1.0 9 O43865,P25098 2
Negative regulation of notch4 signaling 0.6886782723634207 0.688035716188274 0.4914302900718672 1.0 1.0 41 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Downstream signaling events of b cell receptor bcr 0.6979326191095617 0.6801612336193118 0.4964023756632232 1.0 1.0 43 P28070,O00231,O00233,P28072,P62942,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 22
Runx1 regulates transcription of genes involved in differentiation of hscs 0.6968098822704195 0.6763322839682533 0.498829699885682 1.0 1.0 43 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,Q13951,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 22
Ca dependent events 0.4872446914579871 0.674351085724725 0.500088132762005 1.0 1.0 8 P10644,P28482,P25098 3
Regulation of tp53 expression and degradation 0.5056599592760791 0.6739573347205182 0.5003384390787347 1.0 1.0 11 P06493,P30154 2
Degradation of gli1 by the proteasome 0.6900964630298775 0.6730723654392348 0.5009012537745563 1.0 1.0 42 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Dectin 1 mediated noncanonical nf kb signaling 0.6900077089716995 0.6727692345390899 0.5010941133179698 1.0 1.0 42 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Tnfr2 non canonical nf kb pathway 0.6900077089716994 0.6727692345390889 0.5010941133179705 1.0 1.0 42 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Vxpx cargo targeting to cilium 0.497467466142729 0.665897825151691 0.5054764107314778 1.0 1.0 10 Q92538,P18085,Q9UPT5,Q8IYI6,Q96KP1 5
Interleukin 37 signaling 0.5933179723502373 0.6657047504719219 0.5055998365140923 1.0 1.0 3 P40763,Q9H3S7 2
Interleukin 20 family signaling 0.5933179723502373 0.6657047504719219 0.5055998365140923 1.0 1.0 3 P40763,P42224 2
Metabolism of nitric oxide nos3 activation and regulation 0.4726524621618461 0.665477305450957 0.5057452543871628 1.0 1.0 6 P07900 1
Vitamin b5 pantothenate metabolism 0.4709993223384979 0.6587867181831822 0.5100327374091194 1.0 1.0 6 Q9NVE7 1
Sema4d induced cell migration and growth cone collapse 0.4751104427328944 0.6504669243712101 0.5153906600551834 1.0 1.0 7 Q13464,P60660,P35579,Q7Z406,P35580 5
Activation of smo 0.7817448891448335 0.6504352663561275 0.5154111033856612 1.0 1.0 2 P25098 1
Hedgehog ligand biogenesis 0.6832519055937146 0.6498139784528026 0.5158123885119155 1.0 1.0 42 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Receptor mediated mitophagy 0.5114062544250149 0.6490768774060425 0.5162886866223559 1.0 1.0 4 P19784,P68400 2
Diseases of dna repair 0.5093981593940722 0.6408494336301523 0.5216205118954462 1.0 1.0 13 Q9UQ84,Q13472,P52701,P20585 4
Copi independent golgi to er retrograde traffic 0.5930717746591448 0.6399451830155417 0.5222082378770085 1.0 1.0 27 P52907,Q9BVA1,Q9Y6G9,O43237,P20340,Q9H2M9,P68371,P61163,Q13561,Q13409,P47756,P43034,Q9UJW0,Q14203,Q13885,O75935 16
Regulation of runx2 expression and activity 0.696602891393003 0.63714257276406 0.5240319800463284 1.0 1.0 45 Q13309,P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,Q13951,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 23
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.5778879804186658 0.6278878393811235 0.5300774178233421 1.0 1.0 25 P52907,Q13126,P22626,P14174,P17987,Q13177,P37837,Q53EL6,P26038,Q99439,P11233,O00170,O14979 13
Deadenylation of mrna 0.5147007144848055 0.6149834947673367 0.5385656205989668 1.0 1.0 15 Q92600,P11940,Q14240,P23588,P60842,Q5TAX3,Q9NZN8 7
Fceri mediated nf kb activation 0.682683407735685 0.6098934919805955 0.5419323638970415 1.0 1.0 44 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P61088,P25788,P25786,P25787,O00487,P62191 22
Hedgehog on state 0.6822649985656865 0.6085180992043305 0.5428439056244168 1.0 1.0 44 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,P62333,Q99436,Q15008,O43242,P20618,Q6PHR2,P25098,P61289,P25788,P25786,P25787,O00487,P62191 24
Defective cftr causes cystic fibrosis 0.6760494434759703 0.6067225622915984 0.5440350463279624 1.0 1.0 43 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Interleukin 6 signaling 0.4995202342717521 0.6038978141689069 0.545911582142504 1.0 1.0 4 P40763,P42224 2
Interleukin 6 family signaling 0.4995202342717521 0.6038978141689069 0.545911582142504 1.0 1.0 4 P40763,P42224 2
Interleukin 4 and interleukin 13 signaling 0.4935415974783901 0.6033301456049828 0.5462890824769564 1.0 1.0 12 P40763,P07900,P04083,P09601,P11142,P08670 6
Growth hormone receptor signaling 0.4630244004570575 0.6025585824294127 0.5468023803026623 1.0 1.0 7 P40763,P78536,P28482,P27361 4
Regulation of pten stability and activity 0.679902427091932 0.6007710205872144 0.5479925083304897 1.0 1.0 44 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P19784,P25786,P25787,O00487,P62191 22
Signaling by the b cell receptor bcr 0.6959117223586944 0.5978448703411122 0.5499434478509224 1.0 1.0 47 P28070,O00231,O00233,P28072,P62942,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,O43865,P62993,P25787,P25786,O00487,P62191 24
Sema4d in semaphorin signaling 0.4735845603884531 0.5963697351221755 0.5509282541409424 1.0 1.0 9 P63000,Q13464,P60660,P35579,Q7Z406,P35580 6
Ovarian tumor domain proteases 0.4727350779020134 0.5930915375553961 0.5531198935274357 1.0 1.0 9 P06493,Q96FW1 2
Cross presentation of soluble exogenous antigens endosomes 0.6487662635256494 0.5917588487273846 0.5540120831132689 1.0 1.0 39 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Flt3 signaling 0.4667727088832751 0.5879247144367945 0.5565828268648259 1.0 1.0 5 P62993 1
Fcgr3a mediated il10 synthesis 0.4587354281874247 0.5858055032916163 0.558006225069775 1.0 1.0 7 O43865 1
Cyclin a cdk2 associated events at s phase entry 0.6795931271499551 0.5814505906883549 0.5609368093601279 1.0 1.0 45 Q13309,P28070,O00231,O00233,P11802,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 23
Rhobtb2 gtpase cycle 0.5340872153382182 0.5766740180256412 0.5641596872417733 1.0 1.0 20 P07900,P08238,O43396,P78371,P38159,Q16543 6
Metalloprotease dubs 0.4610489074903898 0.5657916718769123 0.5715354085235806 1.0 1.0 5 Q15018 1
The role of gtse1 in g2 m progression after g2 checkpoint 0.7021706747664208 0.5644981834417482 0.5724151360813841 1.0 1.0 50 P28070,O00231,O00233,P28072,P51665,Q15691,P60900,P28074,P28066,P49721,P07900,P08238,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P06493,P25788,Q9BVA1,P25786,P25787,P14635,O00487,P62191 27
Signaling by notch4 0.6630694104114461 0.5644582675708678 0.5724422938956981 1.0 1.0 43 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Dna damage recognition in gg ner 0.5180644604147755 0.5615184776877317 0.5744441374997951 1.0 1.0 18 Q9UBW8,Q9UNS2,P54725,Q9UGN5,Q9H9Q2,Q92905,P61201,Q99627 8
Formation of incision complex in gg ner 0.4995096719127889 0.5586214654286253 0.5764200872545866 1.0 1.0 15 P18074,P15927,P54725,P61956,P61088 5
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.458910585920152 0.5575896885429668 0.5771245992977967 1.0 1.0 5 P09429 1
Ptk6 regulates cell cycle 0.7512237258854122 0.556672795054814 0.5777510075545758 1.0 1.0 2 P11802 1
Clec7a dectin 1 signaling 0.6770630041864519 0.5554934880254969 0.5785571630601365 1.0 1.0 46 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P61088,P25788,O43865,P25786,P25787,O00487,P62191 23
Activation of the pre replicative complex 0.533527820105304 0.5537422179710341 0.5797552778913824 1.0 1.0 21 P25205,P24941,P49642,P49736,Q13416,P15927,O00311,P33991,Q9NR33,Q9NRF9 10
G0 and early g1 0.4434718442264098 0.5501478238120007 0.5822179871627302 1.0 1.0 6 P24941,P06493 2
Metabolic disorders of biological oxidation enzymes 0.4430423584403795 0.5484989248882509 0.583349367279387 1.0 1.0 6 P48637 1
Regulation of hmox1 expression and activity 0.6763988072097403 0.5359791371653001 0.5919729692869713 1.0 1.0 47 Q13309,P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P19784,P25786,P25787,O00487,P62191 23
Erk mapk targets 0.4628856029794338 0.5331354924510326 0.5939397916461095 1.0 1.0 10 P51452,P30153,P30154,P27361 4
Mapk targets nuclear events mediated by map kinases 0.4628856029794338 0.5331354924510326 0.5939397916461095 1.0 1.0 10 P51452,P30153,P30154,P27361 4
Striated muscle contraction 0.4511961653353759 0.5283163559789255 0.597279781288089 1.0 1.0 5 P06753,P67936 2
Hdr through single strand annealing ssa 0.4911270326254535 0.5282667116556962 0.5973142325877625 1.0 1.0 15 P15927,Q9UQ84 2
Processive synthesis on the lagging strand 0.4723033885720991 0.5241801464498618 0.6001532482940648 1.0 1.0 12 P39748,P49642,P15927,P18858,P28340 5
Abc transporter disorders 0.655771607496633 0.5236350210532735 0.6005324183928649 1.0 1.0 44 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Trna modification in the nucleus and cytosol 0.4833532477801542 0.5214867326945754 0.6020277455025731 1.0 1.0 14 Q08J23,Q6YHU6,Q96PZ0,Q9UBP6,Q9NX74,Q96FX7 6
Mtor signalling 0.4770692245005664 0.5200634137377081 0.603019377397084 1.0 1.0 13 Q9Y376,P31946,P23588,Q04637,P62942,P54619 6
Mapk6 mapk4 signaling 0.6820102493080347 0.5192536511968808 0.6035838699422635 1.0 1.0 49 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q13177,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P06493,P25788,P25786,P25787,Q9NZI8,O00487,P62191 24
Uch proteinases 0.6698621878645166 0.5158096868467577 0.6059873362890731 1.0 1.0 47 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Intraflagellar transport 0.4757506925715946 0.5153111974579169 0.6063355755092781 1.0 1.0 13 Q9BVA1,P68371,Q92973,Q9BUF5,Q9BW83,Q9Y547,Q13885 7
Beta catenin phosphorylation cascade 0.4499851227083198 0.507424281769857 0.6118571518865243 1.0 1.0 9 P30154 1
Signaling by ctnnb1 phospho site mutants 0.4499851227083198 0.507424281769857 0.6118571518865243 1.0 1.0 9 P30154 1
Nef and signal transduction 0.7330837892312183 0.503374364519576 0.614701091701096 1.0 1.0 2 Q13177 1
Glutathione synthesis and recycling 0.4366657452840393 0.5019512920648191 0.6157017838000249 1.0 1.0 7 Q8WUX2,P48637,Q96KP4 3
Methionine salvage pathway 0.4434980052324153 0.499628254186692 0.6173368593967474 1.0 1.0 5 Q13126 1
Interleukin 12 signaling 0.5516182190174149 0.4970777605424758 0.6191342168596465 1.0 1.0 27 P52907,Q13126,P22626,P14174,P17987,Q13177,P37837,Q53EL6,P26038,Q99439,P11233,O00170,O14979 13
Pentose phosphate pathway 0.4322836631079804 0.4858195870099822 0.6270950856892965 1.0 1.0 7 Q96G03,O95336,P37837 3
Cargo trafficking to the periciliary membrane 0.5170703464346674 0.4774227853313099 0.6330610922654096 1.0 1.0 22 P50991,P17987,Q92538,P78371,P49368,P18085,Q9UPT5,Q8IYI6,A6NIH7,Q96KP1,P36405 11
Homologous dna pairing and strand exchange 0.4818793296908285 0.4752949051626955 0.6345767900016814 1.0 1.0 16 P15927,Q9UQ84 2
C type lectin receptors clrs 0.670938101026997 0.4699139700017313 0.6384164829958985 1.0 1.0 50 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q13177,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P61088,O43865,P25788,P25786,P25787,O00487,P62191 24
Disassembly of the destruction complex and recruitment of axin to the membrane 0.4449428008640913 0.4680725585359042 0.6397327024464321 1.0 1.0 10 P30154 1
Downregulation of smad2 3 smad4 transcriptional activity 0.4311778585932633 0.4549008970720268 0.6491805375062165 1.0 1.0 5 Q9UPN9,P09874 2
Activation of bad and translocation to mitochondria 0.4286347173111298 0.4515967143058559 0.6515595374715382 1.0 1.0 8 P27348,P31946,P61981,P62258,P63104 5
Interleukin 15 signaling 0.7146559170745886 0.4513572085320216 0.6517321191195908 1.0 1.0 2 P62993 1
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.6551873228128691 0.440113497885917 0.6598549062867611 1.0 1.0 49 P60866,P08708,O75822,P62841,P62847,P62277,Q15056,P08865,P05198,P62241,P11940,P62851,P62263,P62701,Q9UBQ5,Q14152,P62861,P62081,Q14240,P23396,P46782,P46781,P62269,O00303,P62266,Q9Y262,P60842,P23588,P46783,P20042,P39019,P62857 32
Signaling by braf and raf1 fusions 0.5103034101228591 0.436783979164096 0.6622680187472758 1.0 1.0 23 P30086,P51114,P27361,P10398,P36507,P31946,P41240,Q96PU8,P28482,O43252,Q02750 11
Depolymerisation of the nuclear lamina 0.4284137814904312 0.4305634944806326 0.6667857896559801 1.0 1.0 9 P06493,P50402 2
Assembly of the hiv virion 0.7060178520011549 0.4277774088107315 0.6688131859788442 1.0 1.0 2 Q99816 1
Downregulation of erbb2 signaling 0.4147335824027266 0.4231781962498587 0.6721652535864335 1.0 1.0 7 P07900,P40818 2
Meiotic recombination 0.4422524422530969 0.4189864368749829 0.6752260447438687 1.0 1.0 12 P15927,P11802 2
Wnt ligand biogenesis and trafficking 0.4051776610232615 0.4100491472330245 0.681769895300228 1.0 1.0 6 Q9UBQ0 1
Chaperone mediated autophagy 0.416418313850505 0.4091752419574124 0.6824110620321935 1.0 1.0 8 O60664,O95613,P07900 3
Rho gtpases activate nadph oxidases 0.4097491117495409 0.4060057278069323 0.6847383918464378 1.0 1.0 7 Q13526,P28482,P27361 3
Interleukin 1 signaling 0.6368773285088609 0.4039090478109401 0.686279602722565 1.0 1.0 48 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P09429,P61088,P25788,P25786,P25787,O00487,P62191 23
Rhobtb1 gtpase cycle 0.4821536975437318 0.4012408602453402 0.688242800238229 1.0 1.0 20 Q8N684,P38159,P78371,P61201 4
Transport and synthesis of paps 0.5117236676990797 0.4007653445133291 0.68859289604898 1.0 1.0 3 O95340 1
Methylation 0.4136668980716954 0.3998549434598861 0.689263359863364 1.0 1.0 8 Q9NZL9 1
Glucagon like peptide 1 glp1 regulates insulin secretion 0.4151005009161956 0.3989670456481354 0.6899174863307527 1.0 1.0 5 P10644 1
Orc1 removal from chromatin 0.6562329223471217 0.3985059202194319 0.6902572952080968 1.0 1.0 52 O14818,P49736,Q13309,Q13416,P28070,P33991,O00231,P63208,O00233,O75832,P28072,P51665,P60900,P25205,P28074,P28066,P49721,Q06323,P62195,P62333,Q99436,Q15008,O43242,P20618,P61289,P25788,P24941,P25786,P25787,P55036,O00487,P62191,P49720 33
Transcriptional regulation by runx2 0.6719849311880999 0.3981426650837535 0.6905250262662124 1.0 1.0 55 O14818,P27361,Q13309,P28070,O00231,O00233,P11802,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,P62333,Q99436,Q96PK6,Q15008,Q13951,O43242,P20618,P61289,P06493,P25788,P25786,P25787,P14635,O00487,P62191,P17931 31
Activated ntrk2 signals through cdk5 0.6947883674057 0.3979427317162189 0.6906724002995728 1.0 1.0 2 P63000 1
Ctla4 inhibitory signaling 0.4184111917876898 0.3966066555885939 0.6916575438113897 1.0 1.0 9 P30154 1
Hdr through mmej alt nhej 0.4124173118954927 0.3956516251921231 0.6923620468441156 1.0 1.0 8 P18887,Q9UGN5,P39748 3
Maturation of sars cov 2 nucleoprotein 0.3985586688602999 0.3874515684404266 0.6984219330614592 1.0 1.0 6 P49840 1
Epha mediated growth cone collapse 0.4206251810955549 0.3851184984274318 0.7001496232984548 1.0 1.0 10 Q13464,P60660,P35579,Q7Z406,P35580,Q15375 6
Suppression of phagosomal maturation 0.403416274810203 0.3846136478715609 0.7005236810299127 1.0 1.0 7 Q9UI12,P52294,O14964 3
Pi5p regulates tp53 acetylation 0.5046598472733732 0.380294429241456 0.7037268702704742 1.0 1.0 3 Q13526 1
Initiation of nuclear envelope ne reformation 0.4523307112524689 0.3782288899494618 0.7052605657091502 1.0 1.0 16 P30153,P06493,P50402,P63151 4
Caspase activation via dependence receptors in the absence of ligand 0.6861503023322866 0.3756526810110173 0.7071751205697312 1.0 1.0 2 P42574 1
Nuclear events kinase and transcription factor activation 0.4312591970918644 0.3649651760798738 0.7151374013188783 1.0 1.0 13 P51452,P30153,Q00535,P27361,P50570,Q8IV63,P28482,P30154 8
Formation of apoptosome 0.4304055664017153 0.3641413464134839 0.715752463195837 1.0 1.0 4 P27361 1
Tcr signaling 0.6314187314818687 0.3609565656335399 0.7181319167572626 1.0 1.0 50 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q13177,P62195,Q06323,P62333,Q99436,Q15008,O43242,P20618,P41240,P61289,P61088,P25788,P25786,P25787,O00487,P62191 25
Traf6 mediated nf kb activation 0.4026984517763515 0.357915434437323 0.720406599850332 1.0 1.0 5 P09429 1
Degradation of beta catenin by the destruction complex 0.6398815629174495 0.3556681019062674 0.7220891359729933 1.0 1.0 52 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,P30154,O43242,P20618,P61289,P25788,P30153,P25786,P25787,O00487,P62191 23
Notch3 intracellular domain regulates transcription 0.678088108263748 0.3553885035250231 0.7222985603443539 1.0 1.0 2 Q13573 1
Interleukin 9 signaling 0.6780881082637478 0.3553885035250219 0.7222985603443548 1.0 1.0 2 P40763 1
Interleukin 21 signaling 0.6780881082637478 0.3553885035250219 0.7222985603443548 1.0 1.0 2 P40763 1
Rho gtpases activate iqgaps 0.4215019574320665 0.3520001327284366 0.7248381629349128 1.0 1.0 12 P63000,Q9BVA1,P68371,P46940,Q13885 5
Negative regulation of nmda receptor mediated neuronal transmission 0.4042641743212215 0.3506250255291047 0.7258696793893926 1.0 1.0 9 P49593,P07196 2
Processive synthesis on the c strand of the telomere 0.4154640719328053 0.3506141125320403 0.725877867605629 1.0 1.0 11 P15927,P28340,P18858,P39748 4
Hedgehog off state 0.6428040410530399 0.349805463508907 0.7264846984990323 1.0 1.0 53 P10644,O14818,P28070,O00231,P63208,O00233,O75832,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,P62333,Q99436,Q15008,Q13885,O43242,P20618,P61289,P62191,P25788,Q9BVA1,P68371,P25786,P25787,P55036,O00487,Q96J02,P48729,P49720 33
Regulation by c flip 0.6752087532392745 0.3482811897201202 0.7276290190241093 1.0 1.0 2 Q13546 1
Caspase activation via death receptors in the presence of ligand 0.6752087532392745 0.3482811897201202 0.7276290190241093 1.0 1.0 2 Q13546 1
Signaling by mapk mutants 0.6749208177368328 0.3475742764398155 0.7281599275692379 1.0 1.0 2 P28482 1
Tp53 regulates transcription of cell cycle genes 0.4349294018507072 0.3419970790213754 0.73235309047409 1.0 1.0 15 P24941,Q92600,P14635,Q86X55,P06493,Q9NZN8 6
Signaling by tgf beta receptor complex 0.4563127444988678 0.3398269777083171 0.7339868304052342 1.0 1.0 19 P27361,P50750,Q9UPN9,P28482,Q9Y3F4,P09874,Q9Y4E8,P62942 8
Pcp ce pathway 0.6262676406838446 0.3346187712967787 0.737912683002143 1.0 1.0 51 P07737,P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,P62333,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 23
Gastrin creb signalling pathway via pkc and mapk 0.3952720535093277 0.3342850845062137 0.7381644445491253 1.0 1.0 5 P62993,P27361 2
Rho gtpases activate ktn1 0.3983008521515937 0.3320116503954132 0.739880461794906 1.0 1.0 9 Q9NSK0 1
Interleukin 1 family signaling 0.6219806979605276 0.3240833597774561 0.7458749246212535 1.0 1.0 51 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P09429,P61088,P25788,P25786,P25787,O00487,P62191 23
Phase i functionalization of compounds 0.4268432589072543 0.3181338102872274 0.7503834379649257 1.0 1.0 15 P07099,P08238 2
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.6184271435440838 0.3154852319167432 0.7523932622143543 1.0 1.0 51 Q13309,P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,Q12834,O43242,P20618,P61289,P25788,P25786,P25787,Q16763,O00487,P62191 24
Oncogenic mapk signaling 0.4953263062304608 0.3119229452760546 0.7550990840754779 1.0 1.0 28 P30086,P51114,P27361,P10398,P36507,P31946,P41240,Q96PU8,P28482,Q7Z569,O43252,Q02750 12
Interleukin 12 family signaling 0.5041833827798206 0.3069589633150685 0.758874607770452 1.0 1.0 30 P52907,Q13126,P22626,P14174,P17987,Q13177,P37837,Q53EL6,P26038,Q99439,P11233,O00170,O14979 13
Signaling by wnt in cancer 0.3990886060099987 0.3013294441688871 0.7631632905010823 1.0 1.0 11 P30154 1
Estrogen dependent nuclear events downstream of esr membrane signaling 0.4086949783374624 0.2994544932187869 0.7645932889302709 1.0 1.0 4 P27361 1
Signaling by erbb2 0.4037950330422344 0.2991083313824975 0.764857389601687 1.0 1.0 12 P62993,P07900,P40818 3
Fc epsilon receptor fceri signaling 0.6205626721069223 0.296200520260359 0.767076951546144 1.0 1.0 53 O14818,P27361,P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q13177,P62195,Q06323,P62333,Q99436,Q15008,O43242,P20618,P61289,P61088,O43865,P25788,P62993,P25787,P25786,O00487,P62191 28
Metabolism of porphyrins 0.3912883850065158 0.2946135989520675 0.7682890725747735 1.0 1.0 10 P30043,P08397,P53004 3
Insulin processing 0.3892974064527057 0.288897672088249 0.7726596852146441 1.0 1.0 10 Q9UPT5,Q8IYI6 2
Interleukin 17 signaling 0.4211949511914884 0.2868633577878068 0.7742169480738945 1.0 1.0 16 P51452,P30153,P27361,P63208,P28482,P30154,P61088,Q02750 8
Integration of provirus 0.3717343736160782 0.2855166257793303 0.7752483687463643 1.0 1.0 7 P52294,P17096,Q13426 3
Recruitment of mitotic centrosome proteins and complexes 0.5163490207755592 0.2839223341136899 0.7764699003689741 1.0 1.0 34 Q68CZ6,P61163,Q9BSJ2,O43805,Q15691,P07900,O95613,O75935,Q9H6D7,Q13561,P62258,P06493,P43034,P30153,P68371,Q13409,P61981,Q14203,O95684 19
Termination of translesion dna synthesis 0.4304813322798097 0.2827437609800594 0.7773732679736107 1.0 1.0 18 P15927,Q15004,Q14258,Q9NR33,Q9NRF9 5
Association of tric cct with target proteins during biosynthesis 0.4302934294597408 0.2822409698545453 0.7777587453465153 1.0 1.0 18 P40763,Q99832,P50991,P40227,P51784,P17987,Q9H0D6,P78371,P49368,Q9Y2T2,Q9BUR4 11
Map3k8 tpl2 dependent mapk1 3 activation 0.400286229617208 0.2760802363746122 0.7824864400682816 1.0 1.0 4 Q02750 1
Smac xiap regulated apoptotic response 0.642672041462724 0.2729911673592054 0.7848600052239247 1.0 1.0 2 P42574 1
Rho gtpases activate rocks 0.3877833523426766 0.2694816057703389 0.7875590953056004 1.0 1.0 11 Q13464,P60660,O75116,Q16512,P35579,Q7Z406,P35580 7
Beta catenin independent wnt signaling 0.6091374945676485 0.2596042129154932 0.7951690862897558 1.0 1.0 54 P07737,P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,P62333,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 23
Regulation of localization of foxo transcription factors 0.3566395090248498 0.2580916727981149 0.7963361580750796 1.0 1.0 6 P61981,P31946,P63104 3
Interleukin 3 interleukin 5 and gm csf signaling 0.3816247845006497 0.2529237656505665 0.8003271240853 1.0 1.0 11 P62993,P46108 2
Notch1 intracellular domain regulates transcription 0.353957409750543 0.2507114460435905 0.8020372106024409 1.0 1.0 6 Q9BZK7,P63208 2
Signaling by met 0.4227491690839416 0.2490033029829532 0.8033582264612025 1.0 1.0 19 P63000,P62993,P40818,P46108,O14964 5
Signaling by alk in cancer 0.5006903106604847 0.2469988703425309 0.8049090983304974 1.0 1.0 34 P10644,P26641,P27361,Q13501,P63208,P26038,P62753,P28482,Q9HC35,Q92734,O43815,P18206,P40763,P62993,P06753,P35579,P67936,Q14203,P33176 19
Collagen biosynthesis and modifying enzymes 0.3787220944614785 0.245318962648295 0.8062094702023161 1.0 1.0 11 O15460,Q32P28 2
Apc c cdc20 mediated degradation of cyclin b 0.3752905426089882 0.2364960386722271 0.8130477807953405 1.0 1.0 11 P06493,Q16763 2
Irf3 mediated induction of type i ifn 0.3608069164265073 0.2350390950086824 0.814178389598432 1.0 1.0 5 P49959,P13010,P12956,P78527 4
Activation of ppargc1a pgc 1alpha by phosphorylation 0.623092427296298 0.2324019433162431 0.8162258396942366 1.0 1.0 2 P54619 1
Rhobtb gtpase cycle 0.4711196663612084 0.227313624071384 0.8201798799034035 1.0 1.0 30 Q8N684,P07900,P08238,P78371,O43396,P38159,Q16543,P61201 8
Activation of bh3 only proteins 0.3648687819694621 0.2236149254977466 0.8230569488747417 1.0 1.0 10 P27348,P31946,P61981,P62258,P63104 5
Synthesis of diphthamide eef2 0.3797176606165333 0.2231890939263446 0.8233883396626145 1.0 1.0 4 Q9BZG8,Q9BQC3,P13639 3
Semaphorin interactions 0.4261860225979641 0.2197681689429268 0.8260517110764349 1.0 1.0 22 P63000,Q9Y490,Q13464,Q00535,P07900,P08238,P60660,Q13177,P35579,Q7Z406,P35580 11
Met activates ptk2 signaling 0.4403801843318076 0.2183907589331745 0.8271246650821236 1.0 1.0 3 P05556,P07942 2
Fgfr1 mutant receptor activation 0.3676203743856003 0.2174421719674911 0.8278637688232073 1.0 1.0 11 P11274,P62993 2
Purinergic signaling in leishmaniasis infection 0.3765008234681278 0.2154904759807647 0.8293849367196182 1.0 1.0 4 P09601,P08238 2
Dna replication pre initiation 0.6361630390506401 0.2148438500956541 0.8298890636457121 1.0 1.0 64 O14818,P49736,Q13416,P28070,P33991,O00231,O00233,O75832,P28072,P51665,P60900,P25205,P28074,P28066,P49721,P49642,O00311,Q06323,P62195,P62333,Q99436,Q15008,Q9NRF9,P15927,O43242,P20618,P61289,P25788,P24941,P25786,P25787,P55036,O00487,Q9NR33,P62191,P52294,P49720 37
Apc c mediated degradation of cell cycle proteins 0.6054556952168287 0.2125926447954544 0.8316447089129022 1.0 1.0 58 Q13309,P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,Q12834,O43242,P20618,P61289,P06493,P25788,P25786,P25787,Q16763,P14635,O00487,P62191 26
Cdc6 association with the orc origin complex 0.3751080380293944 0.2122066711968682 0.8319458023996564 1.0 1.0 4 Q9Y619,Q13416,Q9UBD5 3
Recruitment of numa to mitotic centrosomes 0.5041161601033687 0.2103987807034856 0.8333564442143775 1.0 1.0 38 Q68CZ6,P61163,Q9BSJ2,O43805,Q15691,P07900,O95613,Q13885,O75935,Q9H6D7,Q13561,P07437,P62258,P06493,P43034,P30153,Q9BVA1,P68371,Q13409,P61981,Q14203,O95684 22
Anchoring of the basal body to the plasma membrane 0.4987547281635666 0.2098393753957914 0.8337930400432128 1.0 1.0 37 Q68CZ6,P61163,O43805,Q15691,Q15051,P07900,O95613,O75935,Q9H6D7,Q13561,P62258,P06493,P43034,P30153,P68371,Q13409,Q15019,P61981,Q14203,O95684 20
Signaling by hedgehog 0.6180103494663672 0.2085828289792762 0.8347739162288752 1.0 1.0 61 P10644,O14818,P28070,O00231,P63208,O00233,O75832,P28072,P51665,P60900,P28074,P28066,P49721,P78536,Q06323,P62195,P62333,Q99436,Q15008,Q13885,O43242,P20618,Q6PHR2,P25098,P61289,P62191,P25788,Q9BVA1,P68371,P25786,P25787,P55036,O00487,Q96J02,P48729,P49720 36
Toll like receptor tlr1 tlr2 cascade 0.4047216461338654 0.2066042225017645 0.836318962336438 1.0 1.0 19 P51452,P30153,P27361,P28482,P09429,P30154,P61088 7
Gap junction trafficking and regulation 0.3681467533272526 0.2062455032988244 0.8365991453328021 1.0 1.0 12 Q9BVA1,P68371,P50570,P09496,P04350,Q07157,Q9BUF5,Q13885 8
Protein folding 0.5001186766299347 0.2024622792402426 0.8395553445384936 1.0 1.0 38 P51784,Q9Y2T2,P50991,P49368,P36404,O75347,Q99471,Q13885,Q9BUR4,P61758,Q99832,O15212,Q99426,Q9H0D6,Q9UHV9,P40763,P19784,Q9BVA1,P68371,P17987,P78371,Q9BUF5,Q9NQP4 23
Regulated necrosis 0.3975287019797361 0.2021528489336523 0.8397972331541714 1.0 1.0 18 P07900,Q96FZ7,Q16543,P09429,Q9UQN3 5
Generation of second messenger molecules 0.3346785817238517 0.2011742382859588 0.8405623345556517 1.0 1.0 6 Q8N8S7,Q13177,Q16512,P19174,P16333 5
Regulation of mrna stability by proteins that bind au rich elements 0.6179017210451865 0.1997353321069306 0.8416875794897405 1.0 1.0 62 O14818,Q14103,P28070,O00231,P31946,O00233,Q92945,P28072,P51665,P60900,P28074,P28066,P49721,P11940,Q06323,P62195,P62333,P11142,Q99436,Q9Y2L1,Q15008,O43242,P20618,P39687,P61289,Q01105,P25788,Q92973,P25786,P25787,Q04637,O00487,P62191 33
Glutathione conjugation 0.3859757411763431 0.1995063181794657 0.8418667015059946 1.0 1.0 16 O43708,P48507,P28161,P48637,Q96KP4,Q8WUX2 6
Synthesis of leukotrienes lt and eoxins ex 0.6032248776274146 0.1950576419301468 0.8453478224242541 1.0 1.0 2 P09960 1
Ptk6 regulates proteins involved in rna processing 0.4254704310995889 0.1878807705996476 0.8509701171326389 1.0 1.0 3 Q07666 1
Signaling by fgfr1 in disease 0.3599017277500276 0.1875789500332121 0.8512067287575187 1.0 1.0 12 P11274,P62993 2
Regulation of plk1 activity at g2 m transition 0.4955758377753825 0.1842999379034386 0.8537781626381302 1.0 1.0 39 Q68CZ6,P61163,P63208,O43805,Q15691,P07900,O95613,O75935,Q9H6D7,Q13561,P62258,P06493,P43034,P30153,P68371,Q13409,P14635,P61981,Q14203,O95684 20
Aurka activation by tpx2 0.4752868743787233 0.1838806435358043 0.8541070900994068 1.0 1.0 35 P30153,P68371,P07900,Q9H6D7,Q68CZ6,P61163,O95613,Q13561,Q13409,O95684,O43805,P43034,P61981,Q14203,P62258,P06493,Q15691,O75935 18
Rho gtpases activate pkns 0.403412962403726 0.1820120745850312 0.8555732500327009 1.0 1.0 21 P63000,P27348,P60660,Q16513,P35579,P31946,Q7Z406,P61981,P62258,P35580,P63104 11
Downregulation of tgf beta receptor signaling 0.3314482661685973 0.1816265675215145 0.8558757977549258 1.0 1.0 7 Q9Y4E8,Q9Y3F4,P62140,Q9Y5K5 4
Activation of atr in response to replication stress 0.3967342579845469 0.178820236300006 0.8580788551216072 1.0 1.0 20 P25205,P24941,P49736,Q13416,P15927,O00311,P33991 7
Signaling by leptin 0.5931471350417566 0.1776326561926552 0.8590114764461863 1.0 1.0 2 P40763 1
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.3994784892946272 0.1741711483249592 0.8617309592538607 1.0 1.0 21 P15927,Q15004,Q14258,Q9NR33,Q9NRF9 5
Alk mutants bind tkis 0.3269555407256881 0.1717420022782157 0.863640363336716 1.0 1.0 7 O43815,P10644,Q9HC35 3
Antigen processing cross presentation 0.557255331796646 0.1714437888599387 0.8638748259120632 1.0 1.0 53 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P09429,P25788,P25786,P25787,O00487,P62191 22
Response of eif2ak4 gcn2 to amino acid deficiency 0.6599881817767068 0.167632948669887 0.8668720486850086 1.0 1.0 75 P60866,P08708,Q02878,Q92616,P62841,P39023,P61254,P61353,P62847,P62277,P46778,P62906,P18124,P32969,P26373,P36578,P08865,P62913,P05198,P18077,P62899,P47914,P62753,P62241,P62424,P62851,P62263,P83881,P62701,P61313,Q07020,P62829,P62917,P61927,P62081,P62861,P35268,P23396,P27635,P05387,P46779,P40429,P25398,P46782,P46781,P62269,P62910,P18621,P15880,P83731,P84098,P30050,P08243,Q02543,P62249,P61513,P62888,P62266,P62750,P42766,P46777,P46783,Q9Y3U8,P20042,P49207,P39019,P62857 67
Pcna dependent long patch base excision repair 0.3786220368553783 0.1631502051161828 0.8704001713463039 1.0 1.0 18 P39748,P15927,P18858,Q9NR33,Q9NRF9 5
Mitotic g1 phase and g1 s transition 0.6752923754816755 0.1627961432399042 0.870678945007985 1.0 1.0 79 P00374,P04818,P49736,Q13309,P28070,O00231,O00233,P11802,P28072,P51665,P60900,P25205,P49721,P28066,P28074,P49642,P62195,Q06323,P62333,Q99436,Q15008,P30154,P31350,Q00534,P15927,O43242,P20618,P61289,P06493,P25788,P30153,P25786,P25787,P14635,Q9NR33,O00487,P62191,P63151 38
Platelet homeostasis 0.3425263184832752 0.1617683554898817 0.8714882734307898 1.0 1.0 11 P30153,P30154 2
Synthesis of gdp mannose 0.5822055859487478 0.1598842188047598 0.872972280161062 1.0 1.0 2 Q96IJ6 1
Eukaryotic translation elongation 0.6591454037080571 0.1597171044510207 0.8731039264703797 1.0 1.0 76 P60866,P08708,Q02878,P26641,P62841,P39023,P61254,P61353,P62847,P62277,P46778,P62906,P18124,P32969,P26373,P36578,P08865,P62913,P18077,P62899,P47914,P62753,P62241,P62424,P62851,P62263,P83881,P62701,P61313,Q07020,P62829,P62917,P61927,P62081,P62861,P35268,P23396,P27635,P05387,P46779,P83731,P40429,P25398,P46782,P46781,P62269,P24534,P62910,P29692,P15880,P18621,P84098,P30050,Q05639,Q02543,P62249,P61513,P62888,P62266,P62750,P42766,P46777,P46783,Q9Y3U8,P49207,P39019,P62857 67
Pyruvate metabolism and citric acid tca cycle 0.4569632842114861 0.1517611847231 0.8793752975569029 1.0 1.0 35 P48735 1
2 ltr circle formation 0.3104845041689489 0.1481542173532992 0.8822210622515578 1.0 1.0 6 Q13426 1
Switching of origins to a post replicative state 0.5745470890377773 0.1466479243451674 0.8834099244191156 1.0 1.0 60 P49736,Q13309,P28070,O00231,O00233,P28072,P51665,P60900,P25205,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,Q16763,O00487,P62191 25
Mitochondrial biogenesis 0.4551683467430839 0.141124710390534 0.8877714229386087 1.0 1.0 36 P48735 1
Sensory processing of sound by outer hair cells of the cochlea 0.344992549542333 0.1380998266622827 0.8901615227677362 1.0 1.0 14 P15311,Q6IBS0,P26038,Q14651,Q12792,P35241 6
Dna strand elongation 0.4085942135469628 0.1371787499175918 0.8908895072163598 1.0 1.0 27 P25205,P39748,P49736,P49642,P15927,Q14566,Q9BRT9,P33991,P18858,P28340,P12004 11
Abc family proteins mediated transport 0.5372129713442036 0.1344554193576267 0.8930424611151859 1.0 1.0 54 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P05198,P49721,Q06323,P62195,P62333,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P20042,P62191 24
Prolactin receptor signaling 0.3917050691244367 0.1294731814723002 0.8969832444025791 1.0 1.0 3 Q06124,P63208 2
Myd88 independent tlr4 cascade 0.3742878753573455 0.1294017163014309 0.8970397896881064 1.0 1.0 21 P51452,P30153,P27361,P28482,P09429,P30154,P61088 7
Signaling by notch 0.5581155207334334 0.1249458258896182 0.90056643879406 1.0 1.0 60 P28070,O00231,O00233,P28072,P67809,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,O43242,P20618,Q9BZK7,P61289,P25788,P20340,P25786,P25787,O00487,P62191 24
Signaling by notch1 0.3122668362099593 0.1241472997054349 0.901198648060344 1.0 1.0 9 P78536,Q9BZK7,P63208,Q96J02 4
Assembly of the orc complex at the origin of replication 0.3115983843046779 0.123017824914863 0.9020929829363644 1.0 1.0 9 O60684,Q13416,Q9UBD5,P52294,P62805,Q9Y619,Q14974,O43913 8
Signaling by cytosolic fgfr1 fusion mutants 0.3097137549566133 0.1198747586824456 0.9045823599192616 1.0 1.0 9 P62993 1
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.372916231933373 0.1197872427888259 0.9046516879515624 1.0 1.0 22 P39748,Q9NX46,P15927,P18858,Q9UGN5,Q9NR33,P28340,Q9NRF9 8
Signaling by ptk6 0.33105644370254 0.1151510604083098 0.908325388684504 1.0 1.0 14 P63000,P24941,Q96JJ3,P46108,P11802,Q07666,P23246 7
Ca2 pathway 0.3813364055299629 0.1145328489232731 0.9088154080452644 1.0 1.0 3 Q9HCE1,P35222 2
Neddylation 0.6169636020716713 0.1133323802671678 0.9097670468671604 1.0 1.0 75 Q9UBW8,Q13309,P28070,O00231,O00233,Q14999,P28072,P51665,Q99627,P60900,P28074,P28066,P49721,P62195,Q06323,Q99436,Q9UNS2,Q15008,Q13617,Q13564,O43242,P20618,Q9BTE7,P61289,P61201,P25788,P25786,P25787,O00487,Q9H9Q2,P62191 31
Retrograde transport at the trans golgi network 0.343581080293396 0.1121778560559902 0.9106823866410204 1.0 1.0 17 O60664,P20645 2
Hiv elongation arrest and recovery 0.3664136427377253 0.1104112580356584 0.9120832250969336 1.0 1.0 22 Q8WX92,Q08945,P62875,P13984,P35269,Q9H3P2,Q14241,Q9Y5B9,P23193 9
Signaling by tgfb family members 0.3615964228609922 0.1103920572792707 0.9120984520038956 1.0 1.0 21 P27361,P50750,Q9UPN9,P28482,Q9Y3F4,P09874,Q9Y4E8,P62942 8
Collagen formation 0.3273330043011457 0.1095451741857556 0.9127700935136496 1.0 1.0 14 O15460,Q32P28 2
Gap filling dna repair synthesis and ligation in gg ner 0.3463137093688228 0.1091655581037215 0.913071177657978 1.0 1.0 18 P15927,P18858,P18887,Q9NR33,Q9NRF9 5
Rho gtpases activate wasps and waves 0.3596407567602551 0.1076706975884737 0.914256914289902 1.0 1.0 21 P63000,P59998,P62993,Q9UQB8,P27361,Q9NZQ3,P61160,Q96F07,P28482,P16333 10
Deadenylation dependent mrna decay 0.4497435829457296 0.1073308871686459 0.9145264816505264 1.0 1.0 40 Q96F86,Q92600,Q969T7,P11940,Q14240,Q5TAX3,P60842,P23588,Q96C86,Q9Y2L1,Q9Y450,Q9Y4Z0,Q9NZN8 13
Sulfur amino acid metabolism 0.3111848398387331 0.1069998221436268 0.91478912085455 1.0 1.0 11 Q13126,Q9BV20 2
Phase ii conjugation of compounds 0.418114345778471 0.1033099113998656 0.9177170095525335 1.0 1.0 34 O43708,Q9NZL9,Q9NX62,P31153,P48507,O95340,Q8WUX2,Q06520,P28161,P48637,Q96KP4,O43252 12
Interleukin 35 signalling 0.3722269798349213 0.1025498327394374 0.9183202604985748 1.0 1.0 3 P40763 1
Interleukin 27 signaling 0.3722269798349213 0.1025498327394374 0.9183202604985748 1.0 1.0 3 P40763 1
Endosomal vacuolar pathway 0.3163353500432205 0.1018295328731567 0.9188919836462092 1.0 1.0 4 P01889,P04439,P10321 3
Sars cov 1 infection 0.3303541604503385 0.1002855710366889 0.9201176123851744 1.0 1.0 16 Q9Y3E7,Q9UQN3,P49840,Q96FZ7 4
Toll like receptor 9 tlr9 cascade 0.3575029410896039 0.0985382602170062 0.9215048925141652 1.0 1.0 22 P51452,P30153,P27361,P28482,P09429,P30154,P61088 7
Cytoprotection by hmox1 0.5599369965789625 0.0967544447768881 0.922921401929144 1.0 1.0 66 P53004,Q13309,P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,P62333,Q99436,Q15008,P30043,O43242,P20618,Q9BZK7,P61289,P25788,P19784,P25786,P25787,O00487,P62191 27
Assembly and cell surface presentation of nmda receptors 0.3074912468927831 0.0950601752655636 0.9242670303131588 1.0 1.0 12 Q9BVA1,P68371,Q92796,P07196,Q13885 5
Lagging strand synthesis 0.3353313931270852 0.0944048332635505 0.924787576565662 1.0 1.0 18 P39748,P15927,P18858,P49642 4
Processing of dna double strand break ends 0.3869385940863592 0.0942254294458149 0.9249300848600148 1.0 1.0 29 Q13472,P15927,Q9UQ84,P61956,P61088,Q9NY27 6
Tcf dependent signaling in response to wnt 0.5653951389099113 0.0934319781082698 0.9255603867658873 1.0 1.0 68 P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,P30154,O43242,P20618,P61289,P25788,P30153,P19784,P25786,P25787,P40818,O00487,P62191 25
Regulation of lipid metabolism by pparalpha 0.3485228114986546 0.0932336489890016 0.9257179427749194 1.0 1.0 21 P11310 1
Nonsense mediated decay nmd 0.6381132440715261 0.0913574119054129 0.927208600560296 1.0 1.0 85 P60866,Q02878,P08708,P62841,P39023,P61254,P61353,P62847,P62277,P46778,P62906,P18124,P32969,P26373,P36578,P08865,P62913,P62899,P18077,P47914,P62753,P62241,P11940,P62424,P62263,P83881,P62851,P62701,P61313,Q07020,P62829,Q9Y5S9,P62917,P62861,P61927,P62081,P35268,P23396,P27635,P05387,P46779,P40429,P25398,P83731,P46781,P62269,P62910,P15170,P15880,P46782,P18621,P84098,P30050,Q02543,P62888,P30153,P62495,P62266,P62750,P42766,P62249,P61513,P46777,P63151,Q04637,P46783,Q9Y3U8,P49207,P39019,P62857 70
Global genome nucleotide excision repair gg ner 0.4446512957626539 0.091158426686926 0.9273667080608314 1.0 1.0 42 Q9UBW8,P15927,P18074,Q92905,P54725,P18858,Q9UGN5,P18887,Q9NR33,Q9H9Q2,Q9UNS2,Q9NRF9,P61088,P61201,Q99627,P61956 16
Thrombin signalling through proteinase activated receptors pars 0.2858479283210738 0.0874730667520655 0.9302954929727888 1.0 1.0 5 P27361 1
Signaling by fgfr 0.366398805005545 0.0868358781354436 0.9308019686963364 1.0 1.0 26 Q01085,P62875,P30153,P31943,P62993,P27361,P52597,P13984,P35269,P26599,P28482,P31483 12
Signaling by fgfr2 0.366398805005545 0.0868358781354436 0.9308019686963364 1.0 1.0 26 Q01085,P62875,P30153,P31943,P62993,P27361,P52597,P13984,P35269,P26599,P28482,P31483 12
Rho gtpases activate cit 0.2958005879660962 0.086052317533427 0.9314248280505122 1.0 1.0 11 P63000,P60660,P35579,O43663,Q7Z406 5
Protein ubiquitination 0.3554135527823586 0.0849745772850331 0.9322816019791756 1.0 1.0 24 O75150,Q16763,Q14527,O75381,P61086,P68036,P61088 7
Nod1 2 signaling pathway 0.270960542709917 0.0841011380003823 0.9329760198579784 1.0 1.0 6 P61088 1
Sensory processing of sound 0.3296364708254582 0.0821191896863776 0.9345519334980384 1.0 1.0 19 P52907,P15311,Q6IBS0,P35579,P47756,P26038,Q14651,Q12792,P35241 9
Formation of tc ner pre incision complex 0.3771378383437525 0.0788086559057815 0.9371848190469594 1.0 1.0 30 Q9UBW8,P18074,Q9UNS2,P23193,P61201,Q99627 6
Other semaphorin interactions 0.5107975813417903 0.0734262413265606 0.9414669363930416 1.0 1.0 2 P05556 1
Ddx58 ifih1 mediated induction of interferon alpha beta 0.3018839890540022 0.0721607208415135 0.9424740038743566 1.0 1.0 15 P07900,P08238,Q14258,P09429,Q13526 5
Perk regulates gene expression 0.2959541800684871 0.0707623198967054 0.9435869209824336 1.0 1.0 14 P08243,P05198,Q9Y2L1,Q92945 4
Signaling by notch1 pest domain mutants in cancer 0.2684992933797998 0.0705177565794425 0.9437815680247524 1.0 1.0 8 P78536,Q9BZK7,P63208 3
Metabolism of water soluble vitamins and cofactors 0.4253318861680684 0.0695189105092129 0.9445765806579912 1.0 1.0 43 P00374,O95396,Q9NVE7,Q9NRN7,O00764,P43490 6
E3 ubiquitin ligases ubiquitinate target proteins 0.3011981834906432 0.063034429190055 0.949739088294395 1.0 1.0 17 O75150,Q14527,O75381,P68036,P61088 5
Eukaryotic translation initiation 0.6523545599876361 0.0620735187683523 0.950504285281528 1.0 1.0 99 Q02878,P62277,Q9NR50,P62906,P32969,P26373,P36578,P08865,P05198,P62753,P83881,P62701,Q9UBQ5,P62829,O60841,P35268,P23396,P40429,P46781,P15880,P84098,Q13144,Q02543,P62888,P23588,P46783,Q9Y3U8,P20042,P08708,P62841,P39023,P61353,P62847,Q9UI10,P47914,P11940,P61313,P62917,P62861,P62269,P62910,Q14232,P55010,O00303,P62266,P62750,P60842,Q04637,P49207,P49770,P61254,P46778,Q15056,P62899,P18077,P62263,Q07020,P61927,P62081,Q14240,O75821,P42766,P62857,P60866,O75822,P18124,P62913,P62241,P62424,P62851,Q14152,P27635,P05387,P46779,P25398,P83731,P46782,P18621,P30050,P62249,P61513,P60228,Q9Y262,P46777,P39019 85
Dna damage bypass 0.3349906974956833 0.0615370061392841 0.9509315436000416 1.0 1.0 25 P15927,Q9NZJ0,Q15004,Q14258,Q9NR33,P28340,Q9NRF9 7
Metabolism of rna 0.2986058409757836 0.0605044592611121 0.951753864381966 1.0 1.0 477 Q02878,Q08J23,Q969T7,P28070,P62277,P62906,P28072,P67809,P26373,P60900,P08865,P49721,P28066,P83881,P62195,P62701,P38159,P62333,P61978,Q99436,Q92733,Q9H2H8,P35637,P62829,P52756,P20618,P39687,P23396,P40429,P46781,Q01105,Q2NL82,P84098,Q9Y4Z0,Q9Y6M1,Q02543,O75937,Q96F86,Q92973,Q9ULX3,P23588,P46783,Q9Y3U8,P62826,Q9UBP6,P08708,Q7L014,O14818,P62841,P39023,P61353,P62847,P31946,O00233,Q99547,Q9BUJ2,Q9H814,P51665,Q9NX74,Q8N684,Q05519,P47914,Q15637,P11940,O60828,P11142,P61313,P82979,Q96FX7,Q07955,Q8IYB3,P62917,Q92600,P62861,P62269,P62910,P25788,P30153,P62266,P62750,P18074,P62191,Q14103,P61254,O00231,P46778,Q92945,Q9NZN8,P28074,P62899,P62263,Q96GA3,Q5TAX3,Q15008,P55795,P61927,P62081,Q14240,P61289,P25786,P25787,P42766,P63151,P62857,P60866,Q96C86,P31943,P22626,P62241,P62424,P62851,Q06323,Q96PZ0,Q9Y2L1,Q9Y5S9,Q6YHU6,O43242,P13984,P05387,P46779,P83731,P46782,P84103,Q9NZI8,O00487,P39019 126
Negative regulation of the pi3k akt network 0.2929908924005072 0.0598383167052747 0.9522844079210137 1.0 1.0 16 P30153,P62993,P27361,O43815,P30154 5
Pten regulation 0.5234579507291839 0.0596267239122198 0.952452933627452 1.0 1.0 69 O14818,P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,P62333,Q99436,Q15008,O43242,P20618,P61289,P25788,P19784,P25786,P25787,O00487,P62191 24
Other interleukin signaling 0.3292351996403199 0.0595974688702289 0.952476234336256 1.0 1.0 3 P42574 1
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.3286290322580683 0.0591407364413325 0.9528400124187316 1.0 1.0 3 Q16566,P52292 2
Camk iv mediated phosphorylation of creb 0.3286290322580683 0.0591407364413325 0.9528400124187316 1.0 1.0 3 Q16566,P52292 2
Cellular response to starvation 0.6027790548497584 0.0577075142191854 0.9539816081916944 1.0 1.0 89 P60866,Q02878,P08708,Q92616,P62841,P39023,P61254,P61353,P62847,P62277,P46778,P62906,P18124,P32969,P26373,P36578,P08865,P62913,P05198,P62899,P18077,P47914,P21281,P62753,P62241,P62424,P62851,P62263,P83881,P62701,P61313,Q07020,P62829,P62917,P62861,P61927,P62081,P35268,P23396,P27635,P05387,P46779,P40429,P25398,P83731,P46781,P62269,P62910,P46782,P15880,Q9UI12,P18621,P84098,P30050,P08243,P62888,Q02543,P62249,P61513,P62266,P62750,P42766,P42345,O75348,P36543,P46777,Q9NXC5,P46783,Q9Y3U8,P20042,P49207,P39019,P62857 73
Repression of wnt target genes 0.3254608294930959 0.0568152096913183 0.9546923979274556 1.0 1.0 3 P56545,Q13363 2
Post translational protein modification 0.2464971799537841 0.0546219889040697 0.9564396202959128 1.0 1.0 409 P28070,Q13309,Q14999,P28072,P61086,P60900,P49721,P28066,Q9BV10,P84085,P62195,P62333,P61978,Q9UJW0,Q99436,Q9HA64,Q15436,Q15907,Q8N6T3,P52907,Q92734,O43731,P20618,O15498,Q92905,P06493,Q13426,Q13263,O43237,Q9ULX3,Q16763,Q96K76,O00743,O95487,Q9UBW8,O14818,P61923,O00233,P51665,Q99627,Q9UBE0,Q9Y6G9,P35606,P11142,P18085,Q8N6H7,P24390,P54578,Q9Y296,P68036,Q12834,Q13561,P61956,P61201,P25788,Q9BVA1,O75150,O14964,P47756,P48444,Q06210,Q14527,P62191,P49720,Q9BW61,Q9BU89,Q9BT78,P61163,O00231,P28074,O43852,P53611,Q9UNS2,Q15008,O75935,Q13564,Q15018,Q9BTE7,Q12907,P61289,P61088,P20340,P25786,P25787,P40818,Q13409,Q9H9Q2,O43505,P51784,P54725,P63241,Q06323,Q13617,O14579,O43242,P53621,Q96FW1,Q9Y6Y8,Q9NZL9,Q14258,O00487,O60493,Q14203 103
Antigen presentation folding assembly and peptide loading of class i mhc 0.2827719133117975 0.0519998808285459 0.9585287883720348 1.0 1.0 16 Q9NZ08,Q15436 2
Diseases of mitotic cell cycle 0.2772553556091721 0.0511564318591811 0.9592008686980658 1.0 1.0 15 Q00534,Q16763 2
Infectious disease 0.3746621007209365 0.0509896553584966 0.9593337636545268 1.0 1.0 367 Q02878,Q9H267,P28070,Q16881,Q9BXS5,P62277,Q9H3P2,P00558,P62906,P28072,P09874,P26373,P62942,P32969,P36578,P60900,P08865,P49721,P28066,Q13464,P62753,Q92804,Q13177,P83881,P62195,P62701,P62333,P61978,Q8WUM4,Q99436,Q9UQN3,P62829,P20618,P36507,P23396,Q13618,P35268,Q13546,P40429,P46781,P13010,P49840,P15880,P16333,P84098,P09601,Q13426,Q13263,Q02543,P62888,O43237,Q96JJ3,P46783,Q9Y3U8,P62826,P23193,P08708,P10644,P17096,O14818,P62841,P39023,P27361,P61353,P62847,O00233,Q9NP79,P51665,Q9Y6G9,P47914,P28482,P61313,Q02750,P62917,P62861,P46108,Q99816,P62269,P62910,Q9UI12,P25788,Q08945,Q9BVA1,P62993,P62266,P62750,P18074,O14964,P62191,P48729,P52294,P49720,P49207,Q9NZZ3,P61254,O00231,P46778,Q9Y3E7,P28074,P62899,P18077,P07900,P08238,P78536,P61160,P62263,Q15008,Q14241,Q13885,Q07020,Q8WX92,P61927,P62081,P19525,Q9BZK7,Q00403,P61289,O43865,P83916,P68371,P25786,P25787,P42766,P55036,Q13409,P35579,P35269,Q9BRG1,P62857,P60866,P39748,Q9UQB8,Q14457,P63208,Q96FZ7,O75832,P18124,P23246,P63000,P62913,P59998,P48556,P29083,P62241,P62424,P62851,Q06323,Q9Y5B9,O43242,P13984,P18858,P05387,P46779,P83731,P46782,Q02790,P14373,P27635,P25398,P18621,P07437,P30050,P62875,P62249,P61513,Q9NZI8,P50750,Q9UN37,P46777,Q9BUF5,O00487,P43487,P39019,Q9H9H4 174
Signaling by ntrks 0.3614673493006528 0.0501001735216591 0.9600425614631852 1.0 1.0 35 P51452,P30153,P62993,P27361,P46108,P36507,P31946,Q9UQ16,P28482,P11233,P30154 11
Cilium assembly 0.4999234391110944 0.0500474702063809 0.9600845599384956 1.0 1.0 68 Q68CZ6,P61163,O43805,Q9BW83,A6NIH7,Q15691,Q15051,P50991,P07900,Q92538,O95613,P49368,P18085,Q13885,O75935,Q9H6D7,Q13561,Q9UPT5,P07437,P62258,P06493,Q9Y547,P43034,P30153,Q9BVA1,Q92973,P68371,P17987,Q13409,P78371,Q15019,Q9BUF5,Q8IYI6,Q14203,P61981,P36405,O95684 37
Costimulation by the cd28 family 0.2824850546598481 0.0488970846636822 0.9610013121863448 1.0 1.0 17 P30153,P30154,Q13177,P62993 4
Resolution of abasic sites ap sites 0.3245675872712605 0.0485174673635648 0.9613038438914644 1.0 1.0 27 P39748,P15927,Q9NX46,P13051,P18858,Q9UGN5,P18887,Q9NR33,P28340,Q9NRF9 10
Muscle contraction 0.3111205960225726 0.0481287081717 0.9616136668982422 1.0 1.0 24 P60660,P06753,Q13177,P04083,Q05682,P67936,P30626,O43865,P18206 9
Cellular responses to stimuli 0.4045129961885159 0.0478767637864261 0.9618144579619106 1.0 1.0 331 Q02878,P53004,Q96EB6,P28070,Q13309,Q16881,P62277,Q14999,P62906,P28072,P26373,P60900,P08865,P49721,P05198,P28066,P83881,P62195,P62701,P62333,Q9UJW0,Q99436,Q8N6T3,P62829,P52907,O43731,P20618,P23396,P30519,P40429,P46781,P49840,P84098,Q02543,O43237,Q16763,Q9NXC5,P46783,Q9Y3U8,P20042,P08708,P17096,O14818,P62841,P39023,P27361,P61353,P62847,O00233,P51665,Q9Y6G9,P47914,O60884,P0DMV9,P11142,P28482,P61313,P62917,Q00534,P62861,P15927,Q13561,P62269,P62910,Q9UBS4,Q9UI12,P25788,Q9BVA1,P62266,P62750,O75348,Q13451,P47756,Q06210,P62191,P49720,P49207,O95429,P31689,Q92616,P61254,P61163,Q9HCE1,O00231,P11802,P46778,Q92945,O95817,P28074,P62899,P18077,P21281,P07900,P08238,P00390,P62263,Q15008,Q99543,Q13885,O75935,Q07020,P31948,P30043,P61927,P62081,Q86X55,Q9BZK7,Q9NWT6,P62258,P61289,P08243,P24941,P19784,P68371,P25786,P25787,P42766,P55036,P42345,Q13409,P62857,P60866,P51858,P62241,P62424,P62851,Q06323,Q99615,Q9Y2L1,Q13617,O43242,P05387,P46779,P83731,P46782,Q02790,O00487,Q14203,P39019 139
Recycling pathway of l1 0.3020577892496862 0.0478039392247724 0.9618724971002062 1.0 1.0 22 Q9BVA1,P15311,Q13885,P26038,Q9UQ16,P28482,P35241 7
Rna polymerase ii transcription 0.2375875729081952 0.047790301337731 0.9618833661371156 1.0 1.0 330 Q96EB6,P28070,Q13309,Q16881,Q9UQ84,Q9H3P2,Q9UHY1,P28072,P60900,P49721,P28066,Q92804,P62195,P62333,Q99436,P30154,P54619,Q9Y255,P20618,P42858,P06493,Q13263,Q16763,Q96SY0,Q9UPN9,P23193,O14818,P27361,P43246,P31946,O00233,Q9C005,Q9H814,P51665,Q8N684,Q05519,O00311,P28482,P82979,Q07955,Q8IYB3,Q92600,Q00534,P15927,P25788,Q08945,P30153,O43809,P18074,Q13451,P61981,P62191,P49720,Q9HAF1,Q9HCE1,O00231,Q9NQ88,Q9NQG5,P11802,Q86U86,Q9NZN8,P28074,P06744,P00390,P53611,Q96PK6,Q15008,Q14241,Q13951,Q13185,P31350,Q8WX92,Q86X55,Q9BZK7,P62258,Q00403,P61289,P24941,P19784,P25786,P25787,P62304,P55036,P42345,P35269,Q96J02,P17931,P63208,O75832,P12004,P63104,P48556,P29083,Q06323,Q9Y5S9,Q13472,O43242,P13984,P84103,Q96P16,P14635,O00487,Q13526 103
Cell cycle 0.3391087936320504 0.0466663217796706 0.9627791724147818 1.0 1.0 317 P00374,P28070,Q13309,Q68CZ6,Q9UQ84,Q9BSJ2,P28072,O95347,P60900,P25205,P49721,P28066,P49642,P62195,P62333,Q99436,Q96IY1,P30154,Q9NRF9,Q9UQN3,P20618,Q01105,P06493,O43237,Q92973,Q16763,Q9UPP1,P62826,O00743,O95684,O14818,P27361,P50402,P33991,P53990,O00233,P31946,P51665,Q9Y6G9,O95613,O00311,P28482,Q12834,Q00534,P15927,Q13561,Q9BRT9,P25788,P30153,Q9BVA1,Q9NR33,P62191,P61163,O00231,P11802,Q15003,P28074,P07900,P08238,Q96GX5,Q15008,O75935,P31350,Q9Y266,P62258,P61289,P61088,P19784,P25786,P25787,Q13409,P63151,P04818,P39748,P49736,Q96FZ7,Q15691,Q06323,Q9BZD4,Q13472,O43242,P18858,Q9UN37,P14635,O00487,Q14203 86
Cellular response to chemical stress 0.5211960996032029 0.045673229731031 0.9635707011152532 1.0 1.0 76 P53004,Q13309,Q16881,P28070,O00231,O00233,P28072,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,P62333,Q99436,Q15008,P30043,O43242,P20618,Q9BZK7,P61289,P25788,P19784,P25786,P25787,O00487,P62191 28
G2 m dna damage checkpoint 0.356948845675313 0.0455120585689891 0.963699163510848 1.0 1.0 36 Q13472,P15927,Q9UQ84,P62258,P06493,P61088 6
Telomere c strand lagging strand synthesis 0.293060391075712 0.0450560971292076 0.9640625952744686 1.0 1.0 21 P15927,P49642,P18858,P39748 4
Mitotic g2 g2 m phases 0.5805415528669805 0.0435139500440551 0.9652918445320556 1.0 1.0 93 P28070,Q68CZ6,P61163,O00231,O00233,Q9BSJ2,P28072,P51665,Q15691,P60900,P49721,P28066,P28074,P07900,P08238,O95613,P62195,Q06323,Q99436,Q15008,P30154,O75935,O43242,P20618,Q13561,P62258,P61289,P06493,P25788,P30153,Q9BVA1,P25786,P25787,Q13409,P14635,O00487,Q14203,P62191,P63151 39
Transcriptional regulation by runx1 0.5137500832657648 0.0431710638947941 0.9655651712426392 1.0 1.0 76 P28070,O00231,O00233,P28072,Q86U86,P51665,P60900,P28074,P28066,P49721,Q06323,P62195,Q99436,Q15008,Q13951,Q00534,O43242,P20618,P61289,P25788,P19784,P25786,P25787,O00487,P62191,P17931 26
Developmental biology 0.3968318000526301 0.0431218426214303 0.9656044075981908 1.0 1.0 276 Q02878,P28070,P62277,P62906,P28072,P26373,P08865,P60900,P49721,P28066,P35080,Q13177,P83881,P62195,P62701,P62333,Q99436,P62829,O96013,P20618,P36507,P23396,P40429,P46781,P84098,Q02543,Q9UQ16,P46783,Q9Y3U8,P07737,P08708,O14818,P62841,P27361,P39023,P61353,P62847,O00233,Q9NR12,P51665,P47914,P11940,P11142,P28482,P61313,Q02750,P62917,Q92600,P62861,P62269,P62910,P25788,Q9BVA1,P62993,P62266,P62750,Q04637,P62191,P49720,P49207,Q9NR77,P61254,O00231,P11802,P26038,P46778,Q15375,P28074,P62899,P18077,P07900,P08238,P61160,P62263,Q15008,Q13951,Q13885,P35241,Q07020,P61927,P62081,Q86X55,Q9BZK7,P61289,P24941,P19784,P68371,P25786,P25787,P62495,P42766,P55036,P35579,P62857,P60866,O75832,P18124,P18433,P63000,P62913,P59998,P15311,P48556,P60660,P62241,P62424,P62851,Q92796,Q06323,Q7Z406,Q9Y5S9,Q13617,O43242,P27635,P05387,P46779,P25398,P83731,P46782,P18621,P30050,P40763,P62875,P62249,P61513,P46777,O00487,P39019 128
Opioid signalling 0.2803371263199272 0.0426987445806309 0.9659416803381412 1.0 1.0 19 P30153,P10644,P25098,P30154,O43865 5
Vesicle mediated transport 0.2614166945730795 0.0426031848556769 0.9660178566494216 1.0 1.0 270 P20645,P84085,Q9UJW0,Q15436,Q15907,Q8N6T3,O95721,P54619,Q9UQN3,P52907,Q92734,O43731,O15260,O15498,P25098,Q9NSK0,P11233,Q92905,Q8TC07,O43237,O60664,Q9UQ16,Q8IYI6,O00743,O95487,Q9UBW8,P61923,P31946,Q9NP79,Q99627,Q9Y6G9,Q9Y6I3,P35606,P11142,P18085,Q8N6H7,P24390,Q9Y296,Q9NVZ3,Q13561,Q99816,Q9UPT5,Q14671,P61201,Q2M2I8,P43034,Q9BVA1,P62993,O60749,O14964,P47756,P48444,P61981,Q9NZZ3,Q9BT78,Q8N1B4,Q9H2M9,Q9H0U4,Q0JRZ9,P61163,Q9UKS6,Q92572,Q14677,P07900,Q9UNS2,O75935,P60520,P62258,Q12907,P20340,Q13409,Q14C86,Q9H9Q2,P55327,Q96FZ7,O14579,P53621,Q8TBA6,Q9Y6Y8,Q9UN37,Q14203,P33176 82
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.2342676846081669 0.0424924339803952 0.9661061431134784 1.0 1.0 8 Q9NZN8 1
Cell cycle mitotic 0.3930465647781247 0.0422574193872952 0.9662934893502404 1.0 1.0 266 P00374,Q13309,P28070,Q68CZ6,Q9BSJ2,P28072,O95347,P60900,P25205,P49721,P28066,P49642,P62195,P62333,Q99436,Q96IY1,P30154,Q9NRF9,Q9UQN3,P20618,Q01105,P06493,O43237,Q92973,Q16763,Q9UPP1,P62826,O95684,O14818,P27361,P50402,P33991,P53990,O00233,P51665,Q9Y6G9,O95613,O00311,P28482,Q12834,Q00534,P15927,Q13561,Q9BRT9,P25788,P30153,Q9BVA1,Q9NR33,P62191,P61163,O00231,P11802,Q15003,P28074,P07900,P08238,Q96GX5,Q15008,O75935,P31350,Q9Y266,P62258,P61289,P19784,P25786,P25787,Q13409,P63151,P04818,P39748,P49736,Q96FZ7,Q15691,Q06323,Q9BZD4,O43242,P18858,Q9UN37,P14635,O00487,Q14203 81
Membrane trafficking 0.2696454159452604 0.0419980986036223 0.9665002138758574 1.0 1.0 263 P20645,P84085,Q9UJW0,Q15436,Q15907,Q8N6T3,O95721,P54619,Q9UQN3,P52907,Q92734,O43731,O15260,O15498,P25098,Q9NSK0,P11233,Q92905,Q8TC07,O43237,O60664,Q9UQ16,Q8IYI6,O00743,O95487,Q9UBW8,P61923,P31946,Q9NP79,Q99627,Q9Y6G9,Q9Y6I3,P35606,P11142,P18085,Q8N6H7,P24390,Q9Y296,Q9NVZ3,Q13561,Q99816,Q9UPT5,Q14671,P61201,Q2M2I8,P43034,Q9BVA1,P62993,O60749,O14964,P47756,P48444,P61981,Q9NZZ3,Q9BT78,Q8N1B4,Q9H2M9,Q9H0U4,Q0JRZ9,P61163,Q9UKS6,Q92572,Q14677,Q9UNS2,O75935,P60520,P62258,Q12907,P20340,Q13409,Q14C86,Q9H9Q2,P55327,Q96FZ7,O14579,P53621,Q8TBA6,Q9Y6Y8,Q9UN37,Q14203,P33176 81
G2 m checkpoints 0.5513816744620621 0.0417452746311245 0.9667017614616572 1.0 1.0 87 O14818,P49736,P28070,Q13416,P33991,P31946,O00231,O00233,Q9UQ84,O75832,P28072,P51665,P63104,P60900,P25205,P49721,P28066,O96028,P28074,O00311,P62195,Q06323,P62333,Q99436,Q15008,Q13472,P15927,O43242,P20618,P62258,P61289,P06493,P61088,P25788,P24941,P25786,P25787,P55036,P14635,O00487,P61981,P62191,P49720 43
Parasite infection 0.319807719576976 0.0417253341436366 0.966717657818308 1.0 1.0 29 P63000,P59998,P62993,Q96JJ3,Q9UQB8,P27361,Q9NZQ3,P46108,P61160,P35579,Q96F07,P28482,P16333 13
Synthesis of dna 0.5392336799860633 0.0415463594542025 0.9668603352372068 1.0 1.0 84 P39748,P49736,Q13309,P28070,O00231,O00233,P28072,P51665,P60900,P25205,P49721,P28066,P28074,P49642,P62195,Q06323,P62333,Q99436,Q15008,P15927,O43242,P20618,Q9BRT9,P18858,P61289,P25788,P25786,P25787,Q16763,Q9NR33,O00487,P62191 32
Selenoamino acid metabolism 0.5657220551002137 0.0415407448848558 0.9668648111513214 1.0 1.0 91 P60866,Q02878,P08708,P62841,P39023,Q16881,P61254,P61353,P62847,P62277,P46778,P62906,P18124,P32969,P26373,P36578,O43252,P47897,P08865,P62913,P62899,P18077,P47914,P00390,P62753,P62241,P62424,P62851,Q96I15,P83881,P62263,P62701,P61313,Q07020,P62829,P62917,P62861,P61927,P62081,P35268,P23396,Q12904,P27635,P05387,P40429,P46779,P25398,P46781,P62269,P62910,P83731,P15880,P46782,P18621,P84098,P30050,P62888,Q02543,P49591,P62249,P62266,P62750,P42766,P61513,P46777,O95340,P46783,Q9Y3U8,P49207,P39019,P62857 71
Ub specific processing proteases 0.5099186234782799 0.0408561256541125 0.9674105948759352 1.0 1.0 77 Q13309,P28070,P51784,O00231,O00233,P28072,P51665,P60900,P49721,P28066,P28074,P62195,Q06323,Q99436,Q15008,Q12834,O43242,P20618,P61289,P25788,Q96FW1,P25786,P25787,P40818,Q9NZL9,O00487,O60493,P62191 28
Metabolism of vitamins and cofactors 0.4104672202760031 0.0405161776202766 0.9676816097554553 1.0 1.0 52 P00374,O75874,P07900,O95396,Q9NVE7,Q9NRN7,O00764,P43490 8
Fgfr2 alternative splicing 0.2753446359146108 0.0401873315433049 0.967943777435953 1.0 1.0 19 Q01085,P62875,P31943,P52597,P13984,P35269,P26599,P31483 8
Selective autophagy 0.328336443678266 0.0400801992185929 0.968029187849963 1.0 1.0 32 P19784,Q9Y6G9,O43237,P07900,Q9NS69,Q9BVA1,P68371,Q13501,O95613,Q13409,P11142,O60664,P61088,Q13885,P54619 15
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.2410656702458547 0.0394239769524963 0.968552363922937 1.0 1.0 11 P08238 1
Nervous system development 0.4812693372361052 0.0389728938331491 0.9689119997769342 1.0 1.0 228 Q02878,P28070,P62277,P62906,P28072,P26373,P08865,P60900,P49721,P28066,P35080,Q13177,P83881,P62195,P62701,P62333,Q99436,P62829,O96013,P20618,P36507,P23396,P40429,P46781,P84098,Q02543,Q9UQ16,P46783,Q9Y3U8,P07737,P08708,O14818,P62841,P27361,P39023,P61353,P62847,O00233,Q9NR12,P51665,P47914,P11940,P11142,P28482,P61313,Q02750,P62917,P62861,P62269,P62910,P25788,Q9BVA1,P62993,P62266,P62750,Q04637,P62191,P49720,P49207,Q9NR77,P61254,O00231,P26038,P46778,Q15375,P28074,P62899,P18077,P07900,P08238,P61160,P62263,Q15008,Q13885,P35241,Q07020,P61927,P62081,P61289,P19784,P68371,P25786,P25787,P62495,P42766,P55036,P35579,P62857,P60866,O75832,P18124,P18433,P63000,P62913,P59998,P15311,P48556,P60660,P62241,P62424,P62851,Q92796,Q06323,Q7Z406,Q9Y5S9,Q13617,O43242,P27635,P05387,P46779,P25398,P83731,P46782,P18621,P30050,P62249,P61513,P46777,O00487,P39019 120
Glycerophospholipid biosynthesis 0.3287008585725739 0.0386077443703917 0.9692031277830911 1.0 1.0 33 P35790,Q8N2A8 2
Translation 0.336508966881778 0.0383678962157094 0.9693943572344564 1.0 1.0 221 Q02878,Q9UHB9,P62277,Q9NR50,P62906,P32969,P26373,P36578,P47897,P08865,Q14197,P05198,P62753,P83881,P62701,Q9UBQ5,Q8N5N7,Q9BRJ2,P62829,O60841,P35268,P23396,P40429,P46781,P24534,P15170,P29692,P15880,P84098,P41250,Q13144,Q02543,P62888,P23588,P46783,Q9Y3U8,P20042,P08708,P26641,P62841,P39023,P61353,P62847,Q9UI10,P47914,P11940,P61313,P82932,P62917,P62861,Q9BYD1,P62269,P62910,Q14232,P55010,O00303,O43776,P62266,P62750,P60842,Q04637,P49207,P49770,P61254,P46778,Q15056,P62899,P18077,P49458,P62263,Q07020,P61927,P62081,Q14240,O75821,P13798,P49591,P62495,P42766,P62857,P60866,O75822,P54577,P18124,P62913,P62241,P62424,P62851,Q92665,Q9Y285,Q14152,P23381,Q12904,P27635,P05387,P26640,P46779,P25398,P83731,P46782,P18621,P30050,Q05639,P62249,P61513,P60228,Q9Y262,P46777,P39019,Q9NSD9 110
Srp dependent cotranslational protein targeting to membrane 0.5479366911336534 0.0382204758339043 0.9695118954676788 1.0 1.0 90 P60866,Q02878,P08708,Q9UHB9,P62841,P39023,P61254,P61353,P62847,P62277,P46778,P62906,P18124,P32969,P26373,P36578,P08865,P62913,P62899,P18077,P47914,P62753,P49458,P62241,P62851,P62263,P83881,P62424,P62701,P61313,Q07020,P62829,P62917,P62861,P61927,P62081,P35268,P23396,P27635,P05387,P46779,P40429,P25398,P83731,P46781,P62269,P62910,P46782,P15880,P18621,P84098,P30050,Q02543,P62888,P62249,P61513,P62266,P62750,P42766,P46777,P46783,Q9Y3U8,P49207,P39019,P62857 65
M phase 0.3620692512582567 0.03698509755982 0.9704968880357516 1.0 1.0 205 O14818,P28070,Q68CZ6,P61163,P50402,O00231,P53990,O00233,Q9BSJ2,Q96FZ7,P28072,P51665,Q15691,O95347,Q15003,P60900,P49721,P28066,P28074,P07900,O95613,P62195,Q06323,P62333,Q96GX5,Q99436,Q96IY1,Q15008,P30154,Q9BZD4,Q9UQN3,O75935,Q12834,O43242,P20618,Q13561,Q9Y266,P62258,Q01105,P06493,P62191,P61289,P25788,P30153,Q9BVA1,O43237,Q92973,P19784,Q16763,P25786,P25787,Q9UN37,Q13409,P14635,Q9UPP1,O00487,Q14203,P62826,P63151,O95684 60
Prevention of phagosomal lysosomal fusion 0.2439471948509575 0.0368549310635054 0.9706006751138794 1.0 1.0 4 O14964 1
Adaptive immune system 0.3865490260325371 0.0362937249672548 0.9710481533958232 1.0 1.0 197 O14818,Q13309,P28070,P19474,P61163,O00231,O00233,Q14999,P28072,P61086,Q8TDB6,P62942,P51665,P60900,P49721,P28066,P28074,O95376,Q13177,P42025,P62195,Q06323,P62333,Q9UJW0,Q15436,Q99436,Q15008,P30154,O75935,P52907,Q12834,Q13617,O43242,P20618,Q13561,Q9NSK0,Q9NZ08,P41240,P61289,P09429,P61088,P25788,O43865,P30153,Q9BVA1,O43237,P62993,P25786,Q16763,P25787,Q13409,Q9UQ16,O00487,Q14203,P62191,P33176,O95487 57
Metabolism of amino acids and derivatives 0.4430008111775903 0.0362073068092112 0.971117059820038 1.0 1.0 196 Q02878,P28070,Q16881,P62277,P62906,P28072,P26373,O43252,P08865,P60900,P49721,P28066,P83881,P62195,P62701,P62333,Q99436,P62829,P12277,O43708,P20618,P23396,P40429,P46781,Q16762,P84098,P78330,Q02543,O95340,P46783,P78540,Q9Y3U8,P08708,O14818,P62841,P39023,P62847,O00233,P61457,P51665,P47914,P62917,P62861,P62269,P62910,P25788,P62266,P62750,P62191,P61254,O00231,P46778,Q13126,P28074,P62899,P34896,P62263,Q15008,P61927,P62081,P61289,P08243,P25786,P25787,P42766,P62857,P60866,P62241,P62424,P62851,Q06323,Q9BV20,Q9BQT8,O43242,P05387,P46779,P83731,P46782,O00487,P39019 80
Hiv transcription elongation 0.2954656537992136 0.0352305126898076 0.9718959317193748 1.0 1.0 27 Q8WX92,Q08945,P62875,P18074,P13984,P35269,Q9H3P2,Q14241,Q9Y5B9,P23193 10
Regulation of expression of slits and robos 0.6411355373380063 0.0352144429573599 0.971908745559753 1.0 1.0 124 P60866,Q02878,P08708,O14818,P62841,P39023,P28070,P61254,O00231,P62847,P62277,O00233,P46778,P62906,P28072,P26373,P51665,P08865,P60900,P49721,P28066,P28074,P47914,P62899,P62241,P11940,P62424,P62263,P83881,P62195,P62701,P62333,P62851,Q06323,Q99436,Q15008,P62829,Q9Y5S9,P62917,Q13617,P62861,P61927,P62081,O43242,P20618,P23396,P05387,P46779,P40429,P83731,P46782,P46781,P62269,P62910,P61289,P84098,P25788,Q02543,P25786,P62266,P62750,P25787,P42766,O00487,P46783,Q9Y3U8,P62191,P39019,P62857 69
Cell junction organization 0.2665798712587793 0.0347806102197454 0.9722546820792984 1.0 1.0 20 Q13418,Q9BY67 2
Cytokine signaling in immune system 0.4294197878810234 0.0347382101231459 0.9722884920307064 1.0 1.0 179 P51452,O14818,P27361,P28070,P19474,O00231,O00233,P26038,P28072,P51665,P60900,Q13126,P49721,P28066,P28074,Q12899,P42574,P07900,P22626,Q13177,P04083,P62195,Q06323,P62333,P11142,P28482,Q99436,Q15008,P30154,Q02750,O15357,P52907,P61221,P14174,P46108,O43242,Q14240,P20618,P41240,P11233,P61289,P09429,O00170,P61088,P25788,P30153,P62993,P25786,P25787,P17987,P37837,P60842,Q9Y4X5,Q04637,Q53EL6,Q14258,O00487,Q99439,P62191,P52294,O14979,Q13526 62
Base excision repair 0.305344609053775 0.0345936551044129 0.972403760966538 1.0 1.0 30 P39748,P15927,P13051,P18858,Q9UGN5,P18887,Q9NR33,Q9NRF9 8
Antigen processing ubiquitination proteasome degradation 0.5355838022754732 0.0342094263620169 0.972710149791998 1.0 1.0 93 Q13309,P28070,P19474,O00231,O00233,Q14999,P28072,P61086,Q8TDB6,P51665,P60900,P49721,P28066,P28074,O95376,P62195,Q06323,Q99436,Q15008,Q12834,Q13617,O43242,P20618,P61289,P61088,P25788,P25786,P25787,Q16763,O00487,P62191 31
Degradation of cysteine and homocysteine 0.2369159649957291 0.0338118883049904 0.9730271558705164 1.0 1.0 4 Q16762 1
Mapk family signaling cascades 0.5359737281830393 0.0338081948559546 0.9730301011326046 1.0 1.0 94 O14818,P27361,P28070,Q9HCE1,O00231,P31946,O00233,O75832,P28072,P18433,P51665,Q9Y4G8,P60900,P63000,P49721,P28066,P28074,P48556,P30086,Q13177,P62195,Q06323,P62333,P36404,P28482,Q99436,P07196,Q15008,P30154,Q02750,O43242,P10398,P20618,P36507,P41240,P61289,P06493,Q7Z569,P25788,P18206,P30153,P62993,P25786,P25787,P55036,Q9NZI8,O00487,P62191,P49720 49
Regulation of tp53 activity through phosphorylation 0.3178283151909055 0.0336637634612153 0.973145275153096 1.0 1.0 34 P19784,Q13472,P15927,Q92804,Q9UQ84,Q13526 6
Rrna processing 0.2768279212824508 0.033614816773122 0.9731843068693944 1.0 1.0 166 P60866,Q02878,P08708,P62841,P39023,P61254,P62847,P62277,P46778,Q99547,P62906,P26373,P08865,P62899,P47914,P62241,P62424,P62851,P62263,P83881,Q96GA3,P62701,Q9Y2L1,P62829,P62917,P62861,P61927,P62081,P23396,P05387,P46779,P40429,P83731,P46782,P46781,P62269,P62910,Q2NL82,P84098,Q02543,Q9ULX3,P62266,P62750,P42766,P46783,Q9Y3U8,P39019,P62857 48
Dual incision in gg ner 0.274886691943489 0.0335776304522768 0.9732139605208144 1.0 1.0 23 P15927,P18074,Q9UGN5,Q9NR33,Q9NRF9 5
Dna replication 0.5208666517206814 0.0331169350202587 0.973581337963769 1.0 1.0 91 O14818,P39748,P49736,Q13309,P28070,Q13416,P33991,O00231,P63208,O00233,O75832,P28072,P12004,P51665,P60900,P25205,P49721,P28066,P28074,P49642,O00311,P62195,Q06323,P62333,Q99436,P28340,Q15008,Q9NRF9,P15927,O43242,P20618,Q9BRT9,P18858,P61289,P25788,P24941,P25786,P25787,Q16763,P55036,Q9NR33,O00487,P62191,P52294,P49720 45
Oxidative stress induced senescence 0.2459420135002983 0.0329861987587375 0.973685593448083 1.0 1.0 16 P11802,P28482,Q00534,P27361 4
Biological oxidations 0.3753335357935239 0.0328595996870659 0.9737865501635204 1.0 1.0 50 P08238,O43708,Q9NZL9,P07099,Q9NX62,P31153,Q8WUX2,O95340,Q06520,P28161,Q96KP4,O00170,O43252 13
Vegfr2 mediated vascular permeability 0.2222872376117703 0.0328374961557754 0.9738041767175454 1.0 1.0 10 P42345,Q13177,P07900 3
Diseases of signal transduction by growth factor receptors and second messengers 0.4399252334322495 0.0328374590105276 0.9738042063391904 1.0 1.0 157 P10644,O14818,P26641,P27361,P28070,Q13501,O00231,P31946,P63208,O00233,P26038,O75832,P28072,P62942,O43252,P51665,P60900,P63000,P49721,P28066,P28074,P56545,P07900,P30086,P51114,P78536,P62195,Q06323,P62333,Q96PU8,P28482,Q99436,Q15008,P30154,Q02750,Q92734,O43815,O43242,P10398,P20618,P36507,P13984,P41240,Q9BZK7,P49840,P61289,Q7Z569,P62191,P25788,P18206,P30153,P62993,P25786,P25787,P06753,P55036,P11274,P42345,P35579,P35269,Q16543,O00487,P67936,Q14203,P48729,P33176,P49720,O95429,O95684 69
Mrna splicing 0.1540936355860103 0.0328371152813155 0.973804480447598 1.0 1.0 157 Q8N684,O75937,Q7L014,P38159,Q92733,P67809,Q9Y4Z0,P35637 8
Signaling by robo receptors 0.628032531574655 0.0325244661720675 0.9740538051645964 1.0 1.0 139 P07737,Q02878,P08708,P60866,O14818,P62841,P39023,P28070,P61254,O00231,P62847,P62277,O00233,P46778,P62906,P28072,P26373,P51665,P08865,P60900,P49721,P28066,P28074,P47914,P62899,P35080,Q13177,P11940,P62263,P83881,P62195,P62701,P62333,P62241,P62424,P62851,Q06323,Q99436,Q15008,P62829,Q9Y5S9,P62917,Q13617,P62861,P61927,P62081,O43242,O96013,P20618,P23396,P05387,P46779,P40429,P83731,P46782,P46781,P62269,P62910,P61289,P84098,P25788,Q02543,P25786,P62266,P62750,P25787,P42766,O00487,P46783,Q9Y3U8,P62191,P39019,P62857 73
Hiv transcription initiation 0.2556547891493513 0.0323560027682837 0.9741881488052472 1.0 1.0 19 Q92804,P18074,Q00403 3
Cytosolic trna aminoacylation 0.2706532007074132 0.0322423011052697 0.974278822297427 1.0 1.0 23 O43324,P49591,O43776,Q9P2J5,P23381,P14868,Q15181,P54577,Q12904,P26640,P54136,P07814,P41250,P47897,Q9Y285,Q9NSD9 16
Copi mediated anterograde transport 0.3889768315404278 0.0319091509599056 0.9745445009464232 1.0 1.0 55 Q9H0U4,P61923,P61163,P83436,Q9Y6G9,P35606,P84085,P18085,Q8N6H7,Q9UJW0,P24390,Q8N6T3,Q13885,O75935,P52907,O43731,O14579,Q13561,O15498,P53621,Q9BVA1,O43237,P68371,Q13409,P47756,P48444,Q14203 27
Cell cycle checkpoints 0.3960319969794033 0.0318867908344418 0.9745623326712832 1.0 1.0 146 O14818,P49736,P28070,P33991,P31946,O00231,O00233,Q9UQ84,P28072,P51665,Q15691,P60900,P25205,P49721,P28066,Q9Y6G9,P28074,O00311,P62195,Q06323,P62333,Q99436,Q96IY1,Q15008,P30154,Q9BZD4,Q12834,Q13472,Q6P1K2,P15927,P20618,O43242,Q9Y266,P62258,P61289,P06493,P61088,P25788,P43034,P30153,O43237,P25786,P25787,Q16763,Q13409,P14635,O00487,P61981,P62191 49
Hiv infection 0.3834382186093003 0.0317139220420869 0.9747001922878088 1.0 1.0 144 Q9NZZ3,P17096,P39748,P28070,O00231,Q96FZ7,O00233,Q9H3P2,Q9NP79,P28072,P51665,P60900,P49721,P28066,P28074,Q92804,Q13177,P62195,Q06323,P62333,Q99436,Q15008,Q14241,Q9UQN3,O43242,P20618,P13984,P18858,Q00403,P61289,P62191,Q13426,P25788,P25786,P25787,P18074,Q9UN37,O00487,P62826,P43487,P23193 41
Mitotic metaphase and anaphase 0.3831524359833984 0.031713920256305 0.9747001937119402 1.0 1.0 144 P28070,P50402,O00231,P53990,O00233,Q96FZ7,P28072,P51665,Q15691,P60900,P49721,P28066,P28074,P62195,Q06323,P62333,Q99436,Q15008,Q9BZD4,P30154,Q9UQN3,Q12834,O43242,P20618,Q9Y266,P61289,P06493,P25788,P30153,Q9BVA1,O43237,P25786,P25787,Q16763,Q9UN37,Q13409,P14635,O00487,P62191,P63151 40
Rho gtpase effectors 0.1888488498133518 0.0304177244198334 0.975733909353045 1.0 1.0 129 P07737,P27361,Q9UQB8,Q16513,P31946,O43663,Q15691,P63104,P63000,P59998,Q9Y6G9,P60660,P35080,Q13177,P61160,Q7Z406,P28482,Q96IY1,Q9BZD4,P30154,Q13885,Q14247,Q12834,Q6P1K2,Q9Y266,Q9NSK0,P62258,P43034,P30153,Q9BVA1,O43237,P62993,P68371,P46940,Q13409,P35579,Q9BUF5,Q99661,P61981,P33176,Q13526 41
Influenza infection 0.4181451479423157 0.0302508797254028 0.975866970924918 1.0 1.0 127 P60866,Q02878,P08708,P62841,P39023,P61254,P61353,P62847,P62277,P46778,P62906,P09874,P18124,P32969,P26373,P36578,P08865,P62913,P62899,P18077,P47914,P07900,P62753,P62241,P62424,P62851,P62263,P83881,P62701,P61313,Q07020,P62829,P62917,P62861,P61927,P62081,P35268,P23396,P13984,P27635,P05387,P40429,P19525,P46779,P46781,P62269,P62910,P25398,P15880,P83731,P46782,P84098,P18621,P30050,Q02543,P62888,P62875,P62249,P62266,P62750,P42766,P61513,P35269,P46777,P46783,Q9Y3U8,P62826,P52294,P49207,P39019,P62857 71
Transcriptional regulation by tp53 0.2471037411317975 0.0302449179756937 0.9758717255373872 1.0 1.0 127 Q16881,P43246,Q9HAF1,Q9HCE1,P31946,Q9NQ88,Q9UQ84,Q9H3P2,Q9NZN8,P06744,P00390,Q92804,P53611,Q14241,P30154,P54619,Q8WX92,Q9Y255,Q92600,Q13472,P15927,P13984,Q86X55,P62258,P06493,Q08945,P30153,P24941,P19784,P18074,P42345,P14635,P61981,P23193,Q13526 35
Signaling by receptor tyrosine kinases 0.1928941610307129 0.030244917768033 0.9758717257030008 1.0 1.0 127 P51452,Q01085,P27361,P16949,Q9UQB8,P31946,P31483,P63000,Q13464,Q00535,Q9Y6I3,P21281,P07900,P31943,Q13177,P78536,P52597,Q8IV63,P28482,P30154,Q02750,Q8WX92,Q9UBC2,P46108,P36507,P13984,P41240,P11233,Q9UI12,P16333,P61201,O43865,P42224,P40763,P30153,P62875,P62993,Q96JJ3,P52272,P50570,P40818,P42345,O75348,P36543,O14964,P35269,P26599,Q16543,Q9UQ16,Q96J02 50
Recognition of dna damage by pcna containing replication complex 0.2482994381509916 0.0301714688351038 0.9759303027396846 1.0 1.0 19 P15927,Q9NZJ0,Q9NR33,P28340,Q9NRF9 5
Signaling by interleukins 0.52803315496375 0.030061846373068 0.9760177291521754 1.0 1.0 113 P51452,O14818,P27361,P28070,O00231,O00233,P26038,P28072,P51665,P60900,Q13126,P49721,P28066,P28074,P42574,P07900,P22626,Q13177,P04083,P62195,Q06323,P62333,P11142,P28482,Q99436,Q15008,P30154,Q02750,O15357,P52907,P14174,P46108,O43242,P20618,P11233,P61289,P09429,O00170,P61088,P25788,P30153,P62993,P25786,P25787,P17987,P37837,Q53EL6,O00487,Q99439,P62191,O14979 51
Dna repair 0.3037428163820317 0.0299857335240818 0.9760784310538833 1.0 1.0 124 Q9UBW8,P52701,P39748,P43246,O95551,P54725,Q9UQ84,Q6P6C2,Q99627,Q15004,P18887,P20585,Q8N9N2,Q9UNS2,Q9NRF9,Q9UNS1,Q9NY27,Q13472,P15927,P13051,P18858,Q92905,P61956,P61088,P61201,Q13426,P18074,Q9UGN5,Q14258,Q9NR33,Q9H9Q2,P23193 32
S phase 0.5002511593904402 0.0298697985193171 0.9761708923874408 1.0 1.0 97 P39748,P49736,Q13309,P28070,O00231,O00233,P11802,P28072,P51665,P60900,P25205,P49721,P28066,P28074,P49642,P62195,Q06323,P62333,Q99436,Q15008,P15927,O43242,P20618,Q9BRT9,P18858,P61289,P25788,P25786,P25787,Q16763,Q9NR33,O00487,P62191 33
Protein methylation 0.2023962607361611 0.0298459348574572 0.9761899243494888 1.0 1.0 7 P11142,O60678 2
Signaling by wnt 0.485208882752114 0.0297984666236609 0.9762277816821484 1.0 1.0 91 P07737,O14818,P28070,Q9HCE1,O00231,P63208,O00233,O75832,Q9UBQ0,P28072,P51665,P63104,P60900,P63000,P49721,P28066,P28074,P56545,P62195,Q06323,P62333,Q99436,Q15008,P30154,O43242,P20618,Q9HCK8,P61289,P62191,P25788,P30153,P19784,P25786,P25787,P40818,P55036,O00487,O60493,P48729,P49720 40
Asparagine n linked glycosylation 0.2472898383160587 0.0296401023692676 0.97635408228665 1.0 1.0 120 P61923,P61163,Q9Y6G9,Q9BV10,P35606,P84085,P18085,Q8N6H7,Q9UJW0,Q15436,P24390,Q8N6T3,Q9Y296,O75935,P52907,Q92734,O43731,O14579,Q13561,O15498,P53621,Q12907,Q9BVA1,O43237,Q9Y6Y8,Q13409,P47756,P48444,Q06210,Q14203,P62191,O00743,O95487 33
Class i mhc mediated antigen processing presentation 0.4584284156531744 0.029469235691933 0.9764903546418032 1.0 1.0 117 Q13309,P28070,P19474,O00231,O00233,Q14999,P28072,P61086,Q8TDB6,P51665,P60900,P49721,P28066,P28074,O95376,P62195,Q06323,P62333,Q99436,Q15008,Q12834,Q13617,O43242,P20618,Q9NZ08,P61289,P09429,P61088,P25788,P25786,P25787,Q16763,O00487,P62191 34
Deubiquitination 0.4881056689127573 0.0294562533246882 0.9765007085773312 1.0 1.0 95 Q13309,P28070,P51784,P54725,O00231,O00233,P28072,P51665,P60900,P49721,P28066,P28074,P62195,Q06323,Q99436,Q15008,Q12834,O43242,P20618,Q15018,P61289,P06493,P25788,Q96FW1,P25786,P25787,P40818,Q9NZL9,Q14258,O00487,O60493,P62191 32
Disorders of transmembrane transporters 0.4421445507363747 0.029146009984293 0.9767481407077216 1.0 1.0 78 P28070,O00231,O00233,P28072,P51665,P60900,P49721,P28066,P28074,P62195,Q06323,Q99436,Q15008,O43242,P20618,P61289,P25788,P25786,P25787,O00487,P62191 21
Retrograde neurotrophin signalling 0.2074437391806104 0.029112016182171 0.9767752523330572 1.0 1.0 9 P63010,P50570,P09496,Q96CW1,Q9UQ16,Q00610,O94973,O95782 8
Apoptosis 0.469660693917042 0.0289424366996465 0.976910500193264 1.0 1.0 91 O14818,P27361,P28070,O00231,P31946,O00233,O75832,P10412,P28072,P08670,P51665,P63104,P60900,P49721,P28066,P28074,P48556,P42574,P26583,Q13177,P62195,Q06323,P62333,P28482,Q99436,Q15008,O43242,P20618,P62258,P61289,P09429,P25788,P25786,P25787,P55036,O00487,P61981,P49720,P62191,P52294,O00429 41
Separation of sister chromatids 0.4003309557756269 0.0288838535392653 0.9769572232588268 1.0 1.0 111 P28070,O00231,O00233,P28072,P51665,Q15691,P60900,P49721,P28066,P28074,P62195,Q06323,P62333,Q99436,Q15008,Q9BZD4,P30154,Q12834,O43242,P20618,Q9Y266,P61289,P25788,P30153,Q9BVA1,O43237,P25786,P25787,Q16763,Q13409,O00487,P62191 32
Intracellular signaling by second messengers 0.4695345249947492 0.0287038145580828 0.9771008140452468 1.0 1.0 95 P10644,O14818,P28070,O00231,O00233,P28072,P51665,P60900,P49721,P28066,P28074,P62195,Q06323,P62333,Q99436,Q15008,P30154,O43815,O43242,P20618,P25098,P49840,P61289,P25788,O43865,P30153,P19784,P62993,P25786,P25787,O00487,P62191 32
Formation of senescence associated heterochromatin foci sahf 0.2060011540680867 0.0286929823973791 0.9771094533006628 1.0 1.0 9 P17096,P06400,P16403,P10412,Q96L91,P07305,P04637,P16402 8
Kinesins 0.2460996906878762 0.0286835583643121 0.9771169694975326 1.0 1.0 20 Q9BVA1,P68371,Q9NSK0,Q9BUF5,Q99661,P33176,Q13885 7
Programmed cell death 0.4562942404753978 0.0285445277545629 0.977227854470866 1.0 1.0 103 O14818,P27361,P28070,O00231,P31946,Q96FZ7,O00233,Q9Y3E7,O75832,P10412,P28072,P08670,P51665,P63104,P60900,P49721,P28066,P28074,P48556,P42574,P07900,P26583,Q13177,P62195,Q06323,P62333,P28482,Q99436,Q15008,Q9UQN3,O43242,P20618,P62258,P61289,P09429,P25788,P25786,P25787,P55036,Q16543,O00487,P61981,P49720,P62191,P52294,O00429 46
Organelle biogenesis and maintenance 0.4188206425202806 0.0283565323596711 0.977377792399122 1.0 1.0 104 P48735,Q68CZ6,P61163,Q9BW83,A6NIH7,Q15691,O75964,Q15051,P50991,P07900,O95613,P49368,P18085,P54619,Q13885,O75935,Q13561,Q86X55,Q9UPT5,Q9BZK7,P62258,Q04837,P06493,Q9Y547,P43034,P30153,Q9BVA1,Q92973,P17987,Q13409,P78371,Q15019,Q8IYI6,P61981,Q14203,P36405,O95684 37
Mitotic prometaphase 0.2612581792866598 0.0278258196628628 0.9778010728199216 1.0 1.0 99 Q68CZ6,P61163,Q9BSJ2,Q15691,O95347,Q15003,P07900,O95613,Q9BZD4,P30154,O75935,Q12834,Q13561,Q9Y266,P62258,P06493,P30153,Q9BVA1,O43237,P19784,Q13409,P14635,Q14203 23
Host interactions of hiv factors 0.3881719316724743 0.0278059689792656 0.9778169052477356 1.0 1.0 98 P17096,P28070,O00231,O00233,P28072,P51665,P60900,P49721,P28066,P28074,Q13177,P62195,Q06323,P62333,Q99436,Q15008,O43242,P20618,P61289,P62191,P25788,P25786,P25787,O00487,P62826,P43487 26
Cargo recognition for clathrin mediated endocytosis 0.3069496914850562 0.0276168291965555 0.9779677590269068 1.0 1.0 39 Q9UBW8,Q9Y6I3,P62993,Q0JRZ9,Q92905,O14964,P25098,P20645,Q9H9Q2,Q9UNS2,P61201,Q9NVZ3,Q2M2I8,Q99627 14
Toll like receptor cascades 0.2725432930939491 0.0275668201501813 0.9780076452871348 1.0 1.0 29 P51452,P30153,P27361,Q9UQ16,P28482,P09429,P30154,P61088 8
Transcription of the hiv genome 0.2895031191159324 0.0275321893919158 0.9780352661507176 1.0 1.0 34 Q8WX92,Q08945,P62875,P29083,Q92804,P18074,P13984,P35269,Q9H3P2,Q00403,Q14241,Q9Y5B9,P23193 13
Intra golgi and retrograde golgi to er traffic 0.3403020689785859 0.0274940816857289 0.9780656601952228 1.0 1.0 95 Q8N1B4,Q9H2M9,P61923,P61163,P20645,Q9Y6G9,P35606,P84085,P18085,Q8N6H7,Q9UJW0,P24390,Q8N6T3,O95721,O75935,P52907,O43731,O14579,O15260,Q13561,O15498,Q9NSK0,P53621,Q8TBA6,P43034,Q9BVA1,O43237,P20340,Q13409,P47756,O60664,P48444,Q14203,P33176 34
Hdr through homologous recombination hrr 0.2605933913904644 0.0272937671434161 0.9782254281172348 1.0 1.0 26 Q9UQ84,P15927 2
Transcription coupled nucleotide excision repair tc ner 0.3317298280307034 0.0271016188886309 0.9783786835497608 1.0 1.0 48 Q9UBW8,P15927,P18074,Q92905,P18858,P18887,Q9NR33,Q9H9Q2,Q9UNS2,P23193,Q9NRF9,P61201,Q99627 13
Hiv life cycle 0.2135043987476374 0.0267026091929042 0.9786969320406484 1.0 1.0 86 Q9NZZ3,P17096,P39748,Q96FZ7,Q9H3P2,Q9NP79,Q92804,Q14241,Q9UQN3,Q99816,P13984,P18858,Q00403,Q13426,Q08945,P18074,Q9UN37,P62826,P52294,P43487,P23193 21
Nucleotide excision repair 0.3553590989858509 0.0266841211973989 0.9787116780723488 1.0 1.0 58 Q9UBW8,P15927,P18074,Q92905,P54725,P18858,Q9UGN5,P18887,Q9NR33,Q9H9Q2,Q9UNS2,P23193,Q9NRF9,P61088,P61201,Q99627,P61956 17
Golgi to er retrograde transport 0.3788173629604554 0.0264823554698142 0.9788726069592756 1.0 1.0 74 Q9H2M9,P61923,P61163,Q9Y6G9,P35606,P84085,P18085,Q8N6H7,Q9UJW0,P24390,Q8N6T3,O75935,P52907,O43731,O14579,O15260,Q13561,Q9NSK0,P53621,P43034,Q9BVA1,O43237,P20340,Q13409,P47756,P48444,Q14203,P33176 28
Er to golgi anterograde transport 0.3709932977371595 0.0263755272191422 0.9789578138078864 1.0 1.0 77 P61923,P61163,Q9Y6G9,P35606,P84085,P18085,Q8N6H7,Q9UJW0,Q15436,P24390,Q8N6T3,Q9Y296,O75935,P52907,Q92734,O43731,O14579,Q13561,O15498,P53621,Q12907,Q9BVA1,O43237,Q9Y6Y8,Q13409,P47756,P48444,Q14203,O00743,O95487 30
Transport to the golgi and subsequent modification 0.3402143901660693 0.0262872868225087 0.9790281950545744 1.0 1.0 80 P61923,P61163,Q9Y6G9,P35606,P84085,P18085,Q8N6H7,Q9UJW0,Q15436,P24390,Q8N6T3,Q9Y296,O75935,P52907,Q92734,O43731,O14579,Q13561,O15498,P53621,Q12907,Q9BVA1,O43237,Q9Y6Y8,Q13409,P47756,P48444,Q14203,O00743,O95487 30
The role of nef in hiv 1 replication and disease pathogenesis 0.2076834199884356 0.0257771329433166 0.9794351010554376 1.0 1.0 13 P63000,P63010,P56377,P04439,Q13177,Q9BXS5,Q10567,Q96CW1,O43747,O94973,Q9UI12,O95782 12
Activation of nmda receptors and postsynaptic events 0.249712051617076 0.0256114271614721 0.9795672715038516 1.0 1.0 26 P63000,P10644,Q9BVA1,P68371,P27361,Q14012,P49593,Q92796,Q9BUF5,P28482,P07196,Q13885,P54619 13
Tp53 regulates transcription of dna repair genes 0.2612773669801708 0.0251372202414509 0.9799455120945232 1.0 1.0 31 Q8WX92,Q08945,P62875,P18074,P43246,P13984,P35269,Q9H3P2,Q14241,Q9Y5B9,P23193 11
Metabolism of nucleotides 0.3024206190173946 0.0250290019319986 0.980031830654319 1.0 1.0 47 P04818,Q08623,Q9UKK9,Q16881,P30566,P11172,Q9BZX2,Q9H773,P00492,P49902,P00390,P30520,P31350,P07741,Q06203,P15531,P32321,Q9NRF8,Q05682,O43598,P17812 21
Resolution of sister chromatid cohesion 0.1904801407364195 0.0249750226638666 0.9800748864197636 1.0 1.0 66 P30153,Q9BVA1,Q12834,O43237,Q13409,Q9Y266,Q9BZD4,P06493,P30154,Q15691 10
Clathrin mediated endocytosis 0.2580787391187094 0.0249113482167232 0.9801256754760675 1.0 1.0 65 Q9UBW8,Q9BT78,Q0JRZ9,Q9UKS6,P20645,Q99627,Q9Y6I3,P11142,Q8N6T3,Q9UNS2,Q9NVZ3,P25098,Q92905,P61201,Q2M2I8,P62993,O14964,Q14C86,Q9UQ16,Q9H9Q2 20
Sars cov infections 0.1426725478522532 0.0248883389099378 0.980144028556349 1.0 1.0 65 P07900,P08238,Q96FZ7,Q02790,P62942,Q9UQN3 6
Interferon signaling 0.2089831358585903 0.0246314753787245 0.9803489131893784 1.0 1.0 62 Q12899,P61221,P27361,Q14240,P19474,P60842,Q14258,Q04637,Q9Y4X5,P61088,Q13526 11
Mhc class ii antigen presentation 0.300435959914419 0.024622765350948 0.9803558606789368 1.0 1.0 56 P52907,Q9BVA1,O43237,P42025,P61163,Q13561,Q13409,Q9NSK0,Q9UQ16,Q9UJW0,Q15436,Q14203,P33176,O95487,O75935 15
Regulation of tp53 activity 0.3005004708318972 0.0246081803759362 0.9803674942802598 1.0 1.0 55 P15927,Q92804,Q9UQ84,P06493,P30154 5
Dna double strand break repair 0.2508120667534949 0.0245725246653076 0.9803959348211828 1.0 1.0 61 Q9UNS1,Q13472,P39748,P15927,O95551,Q9UGN5,Q9UQ84,P18887,Q9NR33,P61956,Q9NRF9,P61088,Q9NY27,Q13426 14
Ire1alpha activates chaperones 0.2446596049294097 0.0243604275361009 0.9805651132022676 1.0 1.0 28 O43731,P51858,Q14999,Q14203,Q9UBS4,Q8N6T3,P49840 7
Copii mediated vesicle transport 0.2519641777631235 0.0242767132521258 0.9806318877890235 1.0 1.0 31 Q9Y6Y8,Q92734,O15498,Q15436,O00743,Q12907,Q9Y296 7
Homology directed repair 0.2807263640420356 0.024201722419 0.9806917042421112 1.0 1.0 45 Q13472,P39748,P15927,Q9UGN5,Q9UQ84,P18887,Q9NR33,P61956,Q9NRF9,P61088,Q9UNS1,Q9NY27 12
Hcmv infection 0.2037881892087692 0.0242012873351115 0.9806920512871792 1.0 1.0 57 P83916,Q9Y6G9,O43237,Q9BVA1,P68371,Q9UN37,Q13409,Q99816,Q96FZ7,P61978,Q9Y3E7,Q9BZK7,Q13885,Q9UQN3,Q13263 15
L1cam interactions 0.2786275629238554 0.0241737323455101 0.980714030557686 1.0 1.0 44 P63000,P19784,P15311,Q9BVA1,Q13885,P27361,P68371,P36507,P11142,P26038,Q9UQ16,P28482,P35241,Q02750 14
Autophagy 0.2713755989123519 0.0240502555374425 0.9808125221613052 1.0 1.0 52 Q13501,Q14457,Q96FZ7,Q9Y3E7,Q9Y6G9,P07900,P08238,O95613,P11142,Q13885,P54619,Q9UQN3,P60520,Q9NS69,Q99816,P61088,P19784,Q9BVA1,O43237,P68371,P42345,Q13409,O60664 23
Copi dependent golgi to er retrograde traffic 0.2701294359598333 0.0240361058928623 0.9808238086815602 1.0 1.0 52 Q9BVA1,O43731,Q9H0U4,P61923,P35606,O14579,P84085,O15260,Q9NSK0,P18085,P48444,Q8N6H7,P24390,P53621,Q8N6T3,P33176,Q13885 17
Nuclear envelope ne reassembly 0.2639505619101298 0.0238704682002512 0.9809559305304798 1.0 1.0 50 P30153,Q9BVA1,Q92973,Q9UN37,P50402,P63151,P53990,Q96FZ7,P14635,P06493,Q9UQN3 11
Gene silencing by rna 0.2546778489846158 0.0237227699995948 0.9810737432821636 1.0 1.0 49 Q99598,O75569,Q8N2A8 3
Extracellular matrix organization 0.2424320131458024 0.0234815069934621 0.9812661896997265 1.0 1.0 32 O15460,P42574,Q9Y296,P55081,Q32P28 5
Formation of rna pol ii elongation complex 0.244994833421255 0.023420930319747 0.9813145096035952 1.0 1.0 34 Q8WX92,Q08945,P62875,Q96ST2,P18074,P13984,P35269,Q9H3P2,Q14241,Q9Y5B9,P23193 11
Intrinsic pathway for apoptosis 0.208087244220895 0.0232974164075448 0.981413032563881 1.0 1.0 19 P40763,P27348,P42574,P27361,P31946,P28482,P61981,P62258,Q9NR28,P63104 10
Leishmania infection 0.1975176659580647 0.0232664435583939 0.9814377386251754 1.0 1.0 46 P10644,Q9UQB8,P27361,Q9NZQ3,P63000,P59998,P08238,P78536,P61160,P28482,P46108,P16333,P09601,O43865,P62993,Q96JJ3,P35579,Q96F07,Q9Y2Z0 19
Unfolded protein response upr 0.2340463406162721 0.0232556213533305 0.9814463711597664 1.0 1.0 44 P08243,P05198,O43731,P51858,Q14999,Q14203,Q9UBS4,Q8N6T3,Q9Y2L1,P49840,P20042,Q92945 12
Apoptotic execution phase 0.2356628189971044 0.0232329739606184 0.9814644362838244 1.0 1.0 31 Q9P289,P42574,P35611,P26583,Q13177,P10412,P07305,P52294,O00429,P09429,P08670 11
Translocation of slc2a4 glut4 to the plasma membrane 0.2440799664974147 0.0232266706348335 0.9814694642533588 1.0 1.0 38 P63000,Q9BVA1,P68371,Q13885,P35579,P31946,Q9UPT5,Q9BUF5,Q8IYI6,Q96KP1,P62258,P11233,P61981,P54619,Q9BZE9,P63104 16
Microrna mirna biogenesis 0.1862498586424411 0.0230778662352946 0.9815881611695498 1.0 1.0 12 O75569,Q9HAV4,P62826 3
Fcgamma receptor fcgr dependent phagocytosis 0.2322633574627981 0.0229448054253327 0.9816943002302064 1.0 1.0 37 P63000,P62993,P07900,Q9UQB8,P08238,P27361,P46108,P61160,Q96JJ3,P35579,P28482,O43865 12
Rab regulation of trafficking 0.1935639343471747 0.0226944442190133 0.9818940075667336 1.0 1.0 39 P60520,P20340,Q9H2M9,Q9H0U4,Q14C86,Q15276,Q15907,P62258,Q8TC07,Q9Y296,Q9NVG8,Q15042 12
Dual incision in tc ner 0.2178973456846007 0.022675639188398 0.9819090079501482 1.0 1.0 36 P15927,P18074,P23193 3
Rab gefs exchange gtp for gdp on rabs 0.2133755014491551 0.0225337520267516 0.982022188605925 1.0 1.0 27 Q9Y296,P20340,P62258 3
Cell cell communication 0.1813225176233652 0.0221253018685513 0.9823480034417154 1.0 1.0 32 P62993,Q9BY67,Q9Y5K6,Q13418,Q15404 5
Tbc rabgaps 0.1890525921811957 0.0220001585010988 0.9824478291036982 1.0 1.0 19 P20340,P60520,Q15907 3
Signaling by vegf 0.1700444944129005 0.0219298298756613 0.9825039296933008 1.0 1.0 30 P63000,Q13464,P07900,Q9UQB8,P46108,Q96JJ3,Q13177,P42345,P16333,O43865 10
Signaling by fgfr in disease 0.1873358859812873 0.0218031883492943 0.982604950857648 1.0 1.0 24 O95429,P11274,P62993 3
Sars cov 2 infection 0.1728868609151476 0.0217359709191148 0.982658569900466 1.0 1.0 27 Q96FZ7,Q9Y3E7,P49840,P48729,Q9UQN3 5
Regulation of mecp2 expression and activity 0.1624645746467699 0.0212725920004854 0.98302820730578 1.0 1.0 12 Q9BZK7,P42858 2
Signaling by fgfr2 in disease 0.1648470512477771 0.0212604896628938 0.9830378613907408 1.0 1.0 14 P62993 1
Dissolution of fibrin clot 0.3771955082061612 0.0169816930608467 0.9864512204883488 1.0 1.0 2 P35237 1
Tp53 regulates transcription of death receptors and ligands 0.3763317016988189 0.0168798576884729 0.9865324617148944 1.0 1.0 2 P49327 1
Interleukin 23 signaling 0.3558882810250505 0.0149508396185692 0.9880714002941804 1.0 1.0 2 P40763 1
P75ntr recruits signalling complexes 0.2939821479988435 0.0126477038179447 0.989908861431946 1.0 1.0 2 Q13501 1
Nf kb is activated and signals survival 0.2939821479988435 0.0126477038179447 0.989908861431946 1.0 1.0 2 Q13501 1
P75ntr signals via nf kb 0.2939821479988435 0.0126477038179447 0.989908861431946 1.0 1.0 2 Q13501 1
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