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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Pink1 prkn mediated mitophagy 0.8153161060976163 2.3864198817916464 0.0170133139738817 0.9999999999699904 1.0 9 Q9NS69,Q8N4H5 2
Transport of bile salts and organic acids metal ions and amine compounds 0.7864340102060913 2.2526700451697543 0.0242799610064563 0.9999999999999992 1.0 9 Q15043,Q8TAD4,Q9H2J7,Q92504,Q8WWI5,P53985 6
Heme degradation 0.9767237461443226 2.1167744079725654 0.0342789983372622 1.0 1.0 3 P30519 1
Synaptic adhesion like molecules 0.801641255011531 2.1075876622731324 0.0350666717048939 1.0 1.0 6 O95197 1
Transport of inorganic cations anions and amino acids oligopeptides 0.7624243977537266 2.0990910666574747 0.0358088737857118 1.0 1.0 11 P30825,Q70HW3,Q9UBX3 3
Class a 1 rhodopsin like receptors 0.7492764405680821 2.098225491190558 0.0358852308103512 1.0 1.0 8 P07602,Q9BYT8,P22466,P42892 4
Peptide ligand binding receptors 0.7492764405680821 2.098225491190558 0.0358852308103512 1.0 1.0 8 P07602,Q9BYT8,P22466,P42892 4
Endosomal vacuolar pathway 0.8923969364343016 2.0960104241055513 0.0360812662478744 1.0 1.0 5 Q9UIQ6,P10321,P30511 3
Pregnenolone biosynthesis 0.8700484854762689 2.035545025535342 0.0417960628941611 1.0 1.0 4 O95772 1
Ras processing 0.8680790510163425 2.000965319664998 0.0453961273864915 1.0 1.0 5 O43924,O60725 2
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.7595875276011801 1.959546678744836 0.0500487988849362 1.0 1.0 7 P10321,P30511 2
Class i peroxisomal membrane protein import 0.7233834208908085 1.9128476860796 0.0557675543829627 1.0 1.0 11 Q9Y5Y5,P51648,Q9NR77,P40855,Q9Y3D6,O75381 6
Synthesis of pc 0.7566282496780917 1.9095005468064028 0.0561975512598527 1.0 1.0 6 P35790 1
Metabolism of steroid hormones 0.75347175637354 1.8954580690394545 0.0580317418201383 1.0 1.0 6 O95772 1
Mitophagy 0.7316152894604544 1.891860688056552 0.0585095448019996 1.0 1.0 14 Q9NS69,Q8N4H5 2
Stimuli sensing channels 0.718875370655706 1.891120814600596 0.0586082185803644 1.0 1.0 11 Q9C0H2,P51798,Q9NW15,Q96PU5,P27105 5
Sphingolipid de novo biosynthesis 0.7143954576469989 1.8694854686877551 0.0615553034668483 1.0 1.0 11 O95470,Q96G23,P51648,P27544,Q9NRA0 5
Gpcr ligand binding 0.7082254376003139 1.8396168148199736 0.0658245139592328 1.0 1.0 11 P07602,Q9BYT8,P22466,P42892 4
Ion transport by p type atpases 0.7035249609108654 1.8168075783668929 0.0692465820235828 1.0 1.0 11 Q9NQ11,P16615,Q9HD20,Q13555,P98194,P05023 6
Formation of atp by chemiosmotic coupling 0.6975450670834739 1.808080643707296 0.0705939502816508 1.0 1.0 10 O75964,P00846 2
Sialic acid metabolism 0.8063911543015446 1.7783453833802332 0.0753471469248086 1.0 1.0 4 P10619 1
Mucopolysaccharidoses 0.8042481565867508 1.7695898590075203 0.076795489429672 1.0 1.0 4 P16278 1
Metabolism of porphyrins 0.6828512846770026 1.7567134081029965 0.078966670964379 1.0 1.0 9 P30519 1
Methionine salvage pathway 0.7993041273424633 1.7493681571611324 0.0802274014318769 1.0 1.0 4 Q13126 1
Bbsome mediated cargo targeting to cilium 0.7123805246435594 1.7435635860203185 0.0812352175596131 1.0 1.0 7 P50991,P78371 2
Metal ion slc transporters 0.8020566004565547 1.7383670837940242 0.0821461528043947 1.0 1.0 5 Q8TAD4,Q92504 2
Zinc transporters 0.8020566004565547 1.7383670837940242 0.0821461528043947 1.0 1.0 5 Q8TAD4,Q92504 2
Heparan sulfate heparin hs gag metabolism 0.6929824368043574 1.6535905548654937 0.0982107330769661 1.0 1.0 7 P54802,P16278 2
O linked glycosylation 0.7730644064212127 1.6415548505818174 0.1006822909738165 1.0 1.0 4 Q8N4A0 1
O linked glycosylation of mucins 0.7730644064212127 1.6415548505818174 0.1006822909738165 1.0 1.0 4 Q8N4A0 1
Oncogene induced senescence 0.6967496497260586 1.6399560119410976 0.1010143133716836 1.0 1.0 6 Q9HCE1,Q00534,P27361 3
Zinc influx into cells by the slc39 gene family 0.8479690584428856 1.6204396411131503 0.1051378702817704 1.0 1.0 3 Q92504 1
Dap12 interactions 0.6916235578150656 1.6165910474539045 0.1059665856596279 1.0 1.0 6 P19174,P10321,P01889 3
Fceri mediated ca 2 mobilization 0.7644007142056555 1.6057905937512629 0.1083199280624933 1.0 1.0 4 P19174,Q08209 2
Pre notch processing in golgi 0.7572775570047894 1.5568737254260396 0.1195004687297269 1.0 1.0 5 Q15363 1
Hs gag degradation 0.8282654684822848 1.5432122087912092 0.1227792960373672 1.0 1.0 3 P16278 1
Activation of bad and translocation to mitochondria 0.666789676066012 1.531104445490536 0.1257435813215721 1.0 1.0 7 P31946,P31751,P27348,P63104 4
Dna replication initiation 0.665871427576381 1.5267914714740014 0.1268128730010551 1.0 1.0 7 Q9NR33,Q14181,Q07864,P49643 4
Cholesterol biosynthesis 0.6662699808423929 1.5151954753556738 0.1297229085852078 1.0 1.0 17 Q16850,P48449,Q15126,Q9BWD1,P37268,Q15125,Q15392,Q15800,Q14739 9
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.6627503539022078 1.4842548379918636 0.1377413265675007 1.0 1.0 6 Q14181,P49643,P30154 3
Vitamin d calciferol metabolism 0.7296300231037479 1.461569011503033 0.143859351375597 1.0 1.0 4 P04062 1
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.6177520644424105 1.4335347349675822 0.1517050797425496 1.0 1.0 9 P31946,P06493,P27348,P62258,O96017,P63104 6
Glycogen breakdown glycogenolysis 0.6457794933620911 1.4321388829603443 0.1521040785140655 1.0 1.0 7 P06737,Q96G03,P11216 3
Golgi cisternae pericentriolar stack reorganization 0.622227832490927 1.4157351717436997 0.1568530565389378 1.0 1.0 11 P06493,P62820,Q9H8Y8,P53350 4
Iron uptake and transport 0.6481379990634384 1.406681048466924 0.159521987848441 1.0 1.0 18 P09601,P21281,P30519 3
P75ntr regulates axonogenesis 0.7904162655954214 1.3944260930646706 0.1631889731833407 1.0 1.0 3 Q9NQC3 1
E2f mediated regulation of dna replication 0.6182620254794113 1.3760132042405044 0.1688175452931788 1.0 1.0 12 P06493,P09884,Q9Y619,P49643,Q14181,P30154 6
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.6171047794795349 1.3702339922917202 0.1706138704596984 1.0 1.0 12 O43681,P46379,P50402,P51648,P09601,P49069 6
Constitutive signaling by akt1 e17k in cancer 0.7070261396756335 1.3673763315997212 0.171507377119505 1.0 1.0 4 P31751 1
Cyclin a b1 b2 associated events during g2 m transition 0.6110097673425876 1.3596155020349845 0.1739516299293146 1.0 1.0 11 P06493,Q9Y570,P53350,P30154 4
Insulin processing 0.6104571956941095 1.3568479594695904 0.1748295251471701 1.0 1.0 11 Q8TAD4,Q9UPT5,Q8NEW0,P33176,Q8TAG9,O60645 6
Glycosphingolipid metabolism 0.6378064871205374 1.355794087495772 0.1751646930409018 1.0 1.0 18 P04062,Q16739,P16278,P10619,P17900,Q9NZJ7,Q16880,P07602,Q13510 9
Regulation of localization of foxo transcription factors 0.703592442533755 1.3365891525833735 0.1813567817526098 1.0 1.0 5 P31946,P31751,P63104 3
E2f enabled inhibition of pre replication complex formation 0.6295126814894149 1.3306515212687318 0.183303701437322 1.0 1.0 6 Q9Y619 1
Activation of nima kinases nek9 nek6 nek7 0.6980993193764508 1.3301225961746015 0.1834778816757558 1.0 1.0 4 P53350 1
Constitutive signaling by egfrviii 0.6975857080672293 1.32797862006456 0.1841851700125083 1.0 1.0 4 P62993,P19174 2
Signaling by egfr in cancer 0.6975857080672293 1.32797862006456 0.1841851700125083 1.0 1.0 4 P62993,P19174 2
Constitutive signaling by ligand responsive egfr cancer variants 0.6975857080672293 1.32797862006456 0.1841851700125083 1.0 1.0 4 P62993,P19174 2
Lipophagy 0.6955092096630945 1.3032543670755523 0.1924879346355477 1.0 1.0 5 Q9Y478,P54619 2
Abc transporters in lipid homeostasis 0.7666094539101774 1.3007784542906384 0.193334298923288 1.0 1.0 3 P40855 1
Metalloprotease dubs 0.6148412594256002 1.285542411042608 0.1986028062591214 1.0 1.0 7 O95630 1
Ros and rns production in phagocytes 0.5868788724260294 1.278178613436958 0.2011864551351405 1.0 1.0 9 Q93050,P21281,Q9Y487 3
Akt phosphorylates targets in the cytosol 0.758998164408515 1.2708669274036064 0.203775993925829 1.0 1.0 3 P31751 1
Synthesis of pa 0.5920236632241862 1.264388922681123 0.2060904668430621 1.0 1.0 11 Q9HCL2,Q9NPH0 2
Gamma carboxylation hypusine formation and arylsulfatase activation 0.5919911037687758 1.264225424933731 0.2061491276339464 1.0 1.0 11 O43681,P38435,Q9BU89,O60725 4
Ion channel transport 0.6672135490874727 1.257379493830276 0.2086162510282481 1.0 1.0 31 Q9NQ11,Q9C0H2,Q12797,P16615,Q9HD20,P51790,Q13555,P98194,P51798,Q9NW15,Q96PU5,P27105,P05023,Q93050,P21281,Q9Y487 16
Amino acid transport across the plasma membrane 0.6807962705464499 1.242523381840416 0.2140435190619336 1.0 1.0 5 P30825 1
Sphingolipid metabolism 0.6540030332525512 1.2297411431988194 0.2187940546064166 1.0 1.0 29 O95470,P16278,Q06136,P10619,P17900,P04062,Q16880,Q16739,Q13510,Q9NZJ7,P07602,Q96G23,P51648,P27544,Q9NRA0 15
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.6734700402330187 1.2273011795556363 0.21970941244528 1.0 1.0 4 Q96JJ3 1
Phosphorylation of emi1 0.7473976569098606 1.2253313043555465 0.2204504182328082 1.0 1.0 3 P53350 1
Glycogen metabolism 0.5800897935633029 1.2241069135526508 0.2209118983297786 1.0 1.0 10 P06737,P11216 2
Cristae formation 0.6121405980828514 1.191320930997909 0.2335276199975544 1.0 1.0 20 O75964,P25705,O75431,Q9BUR5,P00846,Q13505 6
Molybdenum cofactor biosynthesis 0.7379518406869874 1.188318301723143 0.2347080299240924 1.0 1.0 3 O95396 1
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.5931482171177328 1.1823994332649184 0.2370472479769654 1.0 1.0 7 P06493,P12004,Q86X55,Q99873,P14635 5
Cargo trafficking to the periciliary membrane 0.6132619755943168 1.1781471382233049 0.2387379524261752 1.0 1.0 21 Q9NQ48,P36405,Q9UPT5,P78371,P50991,Q10713,O43924,O60645 8
Cardiac conduction 0.5798357664493229 1.1642568144730796 0.2443199520376975 1.0 1.0 13 P16615,Q13555,Q9HD47,P05023,P17252 5
Slc mediated transmembrane transport 0.6429441827736158 1.1584352120124042 0.2466864765285576 1.0 1.0 30 P14672,Q70HW3,Q8TAD4,Q9H2J7,O00400,Q92504,Q8WWI5,P53985,P30825,Q8TB61,Q9UBX3 11
Diseases of carbohydrate metabolism 0.562605710885451 1.1556289511068998 0.247832960792901 1.0 1.0 9 P54802,P10253,P16278,P13807 4
Glycogen storage diseases 0.7268223915970984 1.144807053675935 0.2522890927624241 1.0 1.0 3 P10253 1
Insulin receptor recycling 0.5642132537544917 1.144131849743439 0.2525689608168056 1.0 1.0 10 Q93050,P21281,Q9Y487 3
Unwinding of dna 0.5636935343386597 1.1415142697217535 0.2536559772184057 1.0 1.0 10 Q9BRT9,P33991,P49736,Q14566 4
Transport of connexons to the plasma membrane 0.6507098275687554 1.1324272098210837 0.2574548707007451 1.0 1.0 4 Q9BVA1,P68371 2
Gap junction assembly 0.6507098275687554 1.1324272098210837 0.2574548707007451 1.0 1.0 4 Q9BVA1,P68371 2
Ion homeostasis 0.5648998639213503 1.1281144367152864 0.2592715929304425 1.0 1.0 11 P17252,Q13555,P05023,P16615 4
Carboxyterminal post translational modifications of tubulin 0.6498211617314611 1.114648104223653 0.2650012478019001 1.0 1.0 5 Q9BVA1,P68371 2
Cytochrome p450 arranged by substrate type 0.7190341056689008 1.1144369102904008 0.2650917960624079 1.0 1.0 3 Q16850 1
Negative regulation of nmda receptor mediated neuronal transmission 0.5829028192225303 1.1140954525336562 0.2652382393238066 1.0 1.0 6 P07196,Q14012,Q13555 3
Regulation of tp53 expression and degradation 0.5579480788182839 1.1125834862994577 0.2658873560186536 1.0 1.0 10 P31751,P30154 2
Folding of actin by cct tric 0.5493158337286775 1.1081000290670449 0.2678186184246112 1.0 1.0 8 P78371 1
Mitochondrial calcium ion transport 0.5814685923389973 1.0962319212335416 0.2729772934982262 1.0 1.0 17 P21796,Q9Y277,Q10713,P45880,Q8WWC4 5
Aryl hydrocarbon receptor signalling 0.7137992903022986 1.0940665870731514 0.2739257754082429 1.0 1.0 3 Q15185 1
Transferrin endocytosis and recycling 0.5578651352620525 1.0927913244511955 0.2744854315901768 1.0 1.0 11 Q93050,P21281,Q9Y487 3
Mastl facilitates mitotic progression 0.5778922477203164 1.0908182409195188 0.2753528684102466 1.0 1.0 6 Q96GX5,P30154 2
Signaling by ntrk3 trkc 0.6412262132261667 1.0792216304270223 0.2804889392892418 1.0 1.0 5 Q8WX92,P62993,P19174 3
Wnt ligand biogenesis and trafficking 0.6344936445234413 1.0515065606169087 0.2930259978230445 1.0 1.0 5 O60493,Q9Y3A6 2
Striated muscle contraction 0.6328257708237837 1.0446464076733613 0.2961864225271129 1.0 1.0 5 Q9NYL9 1
Metabolism of polyamines 0.6507181788489533 1.0393109630752082 0.2986601377912046 1.0 1.0 39 P55036,P60900,Q6QHF9,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,P19623,O00231,P62191,P25787,P28074,O00233,P61289 22
Formation of apoptosome 0.6996416083271955 1.0391768794247924 0.2987224812369042 1.0 1.0 3 Q9NR28 1
Cytosolic sulfonation of small molecules 0.6276717151629311 1.0234637452763014 0.3060886331477352 1.0 1.0 5 Q8TB61,P50225 2
G2 m dna replication checkpoint 0.6951965065502207 1.0220125857649214 0.3067749436500897 1.0 1.0 3 P06493,Q99640 2
Metabolism of folate and pterines 0.5568557905891354 1.00998249621167 0.312503676220055 1.0 1.0 7 Q9H2D1,P00374 2
Abortive elongation of hiv 1 transcript in the absence of tat 0.5607609021805476 0.993988952130664 0.3202282460810721 1.0 1.0 17 P35269,P18615,P13984,Q8IXH7,P19388 5
Formation of tubulin folding intermediates by cct tric 0.5417834109644134 0.9932347745293304 0.3205955553784929 1.0 1.0 12 P68371,Q99832,P78371,P50991,Q9BVA1 5
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.5605934243809068 0.993164227811864 0.3206299280278821 1.0 1.0 17 Q9UHV9,Q99471,P61758,P68371,O60925,Q9BUF5,Q99832,P78371,P50991,Q9NQP4,Q9BVA1 11
Cytosolic iron sulfur cluster assembly 0.5529045186601533 0.9912747790359088 0.3215514248109619 1.0 1.0 7 P18074,Q9Y5Y2 2
Synthesis of pe 0.8934807916181798 0.9795820740329794 0.3272924570912778 1.0 1.0 2 P35790 1
Intraflagellar transport 0.5302709039680993 0.9735895425020225 0.3302603807594424 1.0 1.0 10 A0AVF1,Q9BVA1,Q92973 3
Methylation 0.5477244134105826 0.9667817616167 0.333653143781123 1.0 1.0 7 P78417 1
Synthesis of substrates in n glycan biosythesis 0.5382104737109591 0.9567086369523652 0.3387143375028578 1.0 1.0 13 P16278,P10619,Q86YN1 3
Suppression of apoptosis 0.6079812240553373 0.95569822586691 0.3392247191047441 1.0 1.0 4 P28482,P27361 2
Degradation of axin 0.6248202431513138 0.9509085584057678 0.3416507968747391 1.0 1.0 37 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 20
Formation of the early elongation complex 0.5647740819488294 0.940931918424415 0.3467397494098909 1.0 1.0 21 P18074,P35269,P18615,P13984,Q8IXH7,P19388,Q92759 7
Rna polymerase iii transcription initiation from type 3 promoter 0.5416525745026637 0.9381271998058942 0.3481790451612148 1.0 1.0 7 Q9H1D9 1
Rna polymerase iii chain elongation 0.5416525745026637 0.9381271998058942 0.3481790451612148 1.0 1.0 7 Q9H1D9 1
Fgfr2 mutant receptor activation 0.5299119801220613 0.9341791415836136 0.3502114933206801 1.0 1.0 12 P13984,P35269,P19388 3
Signaling by fgfr2 iiia tm 0.5299119801220613 0.9341791415836136 0.3502114933206801 1.0 1.0 12 P13984,P35269,P19388 3
Regulation of ras by gaps 0.6247254714746913 0.9337806891745604 0.3504170326648101 1.0 1.0 38 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 20
Assembly of the hiv virion 0.8736903376018623 0.910627055488093 0.3624919100698154 1.0 1.0 2 Q9H9H4 1
Cross presentation of soluble exogenous antigens endosomes 0.6196651597922112 0.9100813033859472 0.362779633908455 1.0 1.0 38 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 20
Role of phospholipids in phagocytosis 0.5977578409689331 0.9012005504519698 0.3674816983514573 1.0 1.0 5 Q8IV08 1
Rna polymerase iii transcription termination 0.5049226268750753 0.8846441022208078 0.3763486125070145 1.0 1.0 8 Q9H1D9 1
Cdt1 association with the cdc6 orc origin complex 0.6247059027694242 0.8844004148903226 0.3764800990885684 1.0 1.0 41 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,Q9Y619,O00231,P62191,P25787,P28074,O00233,P61289 21
Degradation of dvl 0.6158238139117799 0.8757257354657443 0.3811791511692548 1.0 1.0 39 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 20
Signal attenuation 0.6554256526593045 0.8704187238184133 0.3840716179859331 1.0 1.0 3 P27361 1
Stabilization of p53 0.6145975439388309 0.8700247036528616 0.3842869040813346 1.0 1.0 39 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 20
Mitochondrial protein import 0.6068527153322545 0.8667271266758597 0.3860915386572969 1.0 1.0 37 P21796,P25705,O14925,Q99595,O75431,O60830,Q9NS69,Q9Y5J7,Q8N4H5,Q13505,Q10713 11
G1 s specific transcription 0.5087298719175728 0.8662888988538306 0.386331752489466 1.0 1.0 10 Q9Y619,P00374,P31350 3
Activation of the pre replicative complex 0.552202866811237 0.862443231384229 0.3884436594800688 1.0 1.0 22 P33991,Q14566,P09884,P33993,Q9NR33,Q9Y619,Q07864,P49736,P49643,Q14181 10
Defective cftr causes cystic fibrosis 0.6234022626801908 0.8622015649636593 0.3885766086714295 1.0 1.0 42 P55036,P60900,Q9BUN8,P28072,O43242,Q15008,O75477,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O94905,O00231,P62191,P25787,P28074,O00233,P61289 23
Recruitment of mitotic centrosome proteins and complexes 0.6079235206777736 0.8553298314889616 0.392368577136934 1.0 1.0 38 P06493,Q15154,P17252,O43805,Q9UGJ1,Q13561,Q96CS2,Q9BSJ2,Q68CZ6,Q14203,P43034,O94927,P68371,P62258,O95684,Q15691,O75935,P53350,P61163,P23258,Q9H6D7,Q96CW5 22
Rap1 signalling 0.5832211583836775 0.8548824560071433 0.3926162239605006 1.0 1.0 4 P17252,P31946 2
Fceri mediated mapk activation 0.5233626769888142 0.8522737391003278 0.3940621779151283 1.0 1.0 7 P19174,P27361 2
Transcriptional regulation of white adipocyte differentiation 0.5167145310179689 0.8506266045313763 0.3949768058472866 1.0 1.0 13 O75448,P14672 2
Diseases associated with glycosylation precursor biosynthesis 0.5223841585222497 0.8477041010009633 0.3966027818821334 1.0 1.0 7 P10619 1
Regulation of runx3 expression and activity 0.6054484417294722 0.8438365608112864 0.3987607421145123 1.0 1.0 38 P55036,P60900,P28072,O43242,Q15008,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 19
Dap12 signaling 0.5748995741400934 0.8213913968648735 0.4114233623616168 1.0 1.0 4 P62993,P19174 2
Vxpx cargo targeting to cilium 0.4985646698034808 0.8160958263745256 0.4144453308184703 1.0 1.0 10 Q9UPT5,O60645 2
Abc transporter disorders 0.6182430623887162 0.8066837338678676 0.4198487179204604 1.0 1.0 44 P55036,P60900,Q9BUN8,P28072,O43242,Q15008,O75477,Q14997,Q9UL46,P28070,P49720,Q9NUN5,Q99436,P49721,O75832,O00487,P20618,O94905,O00231,P62191,P25787,P28074,O00233,P61289 24
Regulation of pten stability and activity 0.6180361559861243 0.8057394415749454 0.4203931024336098 1.0 1.0 44 P55036,P60900,P28072,P46934,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P31751,P25787,P28074,O00233,P61289 22
Negative regulation of notch4 signaling 0.599450887005477 0.7999728438175118 0.4237265311710452 1.0 1.0 39 P55036,P60900,P28072,O43242,Q15008,Q9UL46,P28070,P49720,P62333,Q99436,P63104,O75832,P49721,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 21
Nef mediated downregulation of mhc class i complex cell surface expression 0.5683343155838751 0.7951360240112043 0.4265343815335867 1.0 1.0 4 Q10567 1
Copi independent golgi to er retrograde traffic 0.5543528168441079 0.7869804124303011 0.4312933326285582 1.0 1.0 27 Q13561,P68371,O43237,O75935,P61163,P47756,Q9NZ32,Q14203,Q9UJW0,Q10472,P43034,Q9H2M9,Q9BVA1,Q8TD16 14
Cellular response to hypoxia 0.5991602380191288 0.7826870529692872 0.4338109069725075 1.0 1.0 40 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,Q15369,P62191,P25787,P28074,O00233,P61289 21
Proton coupled monocarboxylate transport 0.8355646100116481 0.7810995603223053 0.4347439404987325 1.0 1.0 2 P53985 1
Activation of ppargc1a pgc 1alpha by phosphorylation 0.5642921868876134 0.7790506720916565 0.4359498659782392 1.0 1.0 4 Q9Y478 1
G1 s dna damage checkpoints 0.5999535157996391 0.7704912195319599 0.4410085615234396 1.0 1.0 41 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 20
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6281428715071034 0.7692188331538337 0.441763412005967 1.0 1.0 3 Q00534 1
Recycling of eif2 gdp 0.5037270186260497 0.761164260706987 0.4465589620376853 1.0 1.0 7 P49770,Q9NR50,Q14232 3
Assembly and cell surface presentation of nmda receptors 0.4873111789586695 0.7609722008131279 0.4466736716117729 1.0 1.0 10 P07196,P68371,Q13555,Q15334,Q9BVA1 5
Post chaperonin tubulin folding pathway 0.4834418918852543 0.7600619846654295 0.4472175347357585 1.0 1.0 9 P68371,O75347,Q9BVA1,Q99426,Q9BUF5 5
Acyl chain remodelling of pc 0.5592350852236273 0.7590176872442332 0.4478419763673684 1.0 1.0 4 Q9NP80 1
Smad2 smad3 smad4 heterotrimer regulates transcription 0.5592122616764407 0.758927514097717 0.4478959189725984 1.0 1.0 4 P50750,P27361 2
Anchoring of the basal body to the plasma membrane 0.5798829728944412 0.7580944900029085 0.4483944180467092 1.0 1.0 36 P06493,Q13561,P68371,O75935,P53350,Q15154,Q96CS2,Q68CZ6,P61163,Q14203,Q9H6D7,O95684,P43034,Q15691,P17252,O43805,O94927 17
The role of gtse1 in g2 m progression after g2 checkpoint 0.6208479168913568 0.7564627455084754 0.4493718005770408 1.0 1.0 48 P06493,P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,Q9BVA1,O00487,P20618,O00231,Q15691,P53350,P62191,P25787,P28074,O00233,P61289 25
Miscellaneous transport and binding events 0.5022731253481676 0.7544737375221482 0.4505648093058019 1.0 1.0 7 Q9UEY8 1
Glycosaminoglycan metabolism 0.511347884215629 0.7535990595774597 0.4510900092014958 1.0 1.0 17 Q8NCH0,P54802,P16278,Q8TB61 4
Metabolism of fat soluble vitamins 0.5015469506903614 0.7511352662333812 0.4525712535873381 1.0 1.0 7 Q8N0U8 1
Signaling by fgfr2 in disease 0.4989310833666905 0.7463295348532092 0.4554683742356422 1.0 1.0 14 P13984,P30876,P35269,P19388 4
Aurka activation by tpx2 0.5756263258144265 0.7385861022971971 0.460158365838387 1.0 1.0 36 P06493,Q13561,P68371,O75935,P53350,Q15154,Q96CS2,Q68CZ6,P61163,Q14203,Q9H6D7,O95684,P43034,Q15691,P17252,O43805,O94927 17
Degradation of gli1 by the proteasome 0.5963116761770567 0.7382989750186608 0.4603327892164497 1.0 1.0 42 P55036,P60900,P28072,O43242,Q15008,P17252,Q14997,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 22
Phase 0 rapid depolarisation 0.8207217694994334 0.7321220128552299 0.464094099111233 1.0 1.0 2 Q9HD47 1
Camk iv mediated phosphorylation of creb 0.8207217694994174 0.7321220128551797 0.4640940991112636 1.0 1.0 2 P52292 1
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.8207217694994174 0.7321220128551797 0.4640940991112636 1.0 1.0 2 P52292 1
Phase i functionalization of compounds 0.4994614068808862 0.7314361573687808 0.4645127867995 1.0 1.0 15 Q16850,O43169,Q6QHF9 3
Plasma lipoprotein assembly 0.5481332347002786 0.7154263685521655 0.4743456237813044 1.0 1.0 4 Q9Y6B6 1
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.5026530729701726 0.7122029915812632 0.476339084723385 1.0 1.0 17 P16278,O95394,P10619,Q86YN1,Q9BT22 5
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.550369506548045 0.7116336868764704 0.4766916411129742 1.0 1.0 5 P30154 1
Asymmetric localization of pcp proteins 0.5792022049341077 0.7076202771552975 0.4791810972603778 1.0 1.0 39 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 20
Retrograde transport at the trans golgi network 0.5155335945842341 0.7052760450866082 0.4806384650178756 1.0 1.0 21 Q5VIR6,Q5VZE5,P20645,Q8N1B4 4
Hedgehog on state 0.5860982338470708 0.6923349182280913 0.4887270264514112 1.0 1.0 42 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P48729,P25787,P28074,O00233,P61289 21
Dectin 1 mediated noncanonical nf kb signaling 0.5858422740733401 0.6911892731303987 0.4894466040575818 1.0 1.0 42 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 21
Tnfr2 non canonical nf kb pathway 0.5858422740733401 0.6911892731303987 0.4894466040575818 1.0 1.0 42 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 21
Phosphorylation of the apc c 0.4836238081206726 0.6904285284430598 0.4899247413774754 1.0 1.0 13 P06493,Q96DE5,P53350,Q9UJX3 4
Hur elavl1 binds and stabilizes mrna 0.4850171331128128 0.6757874502715413 0.4991756037103823 1.0 1.0 7 Q01105 1
Peptide hormone metabolism 0.4969962576569938 0.6686650693732059 0.5037091545487957 1.0 1.0 18 O75787,Q8TAD4,O60645 3
Scf skp2 mediated degradation of p27 p21 0.5803962171879031 0.6668912662068596 0.5048415900872307 1.0 1.0 42 P55036,P60900,P28072,O43242,Q15008,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P11802,P28074,O00233,P61289 21
Hiv transcription initiation 0.4924632579263266 0.6641866247560271 0.5065708729399738 1.0 1.0 17 P18074,P35269,P13984,P19388,Q92759 5
Association of tric cct with target proteins during biosynthesis 0.5015826368390739 0.6568233536153734 0.5112945060770291 1.0 1.0 20 P04062,O95302,P50991,P78371,Q9Y2T2,P61962 6
Plasma lipoprotein clearance 0.4836407895633268 0.6564183932007724 0.5115549590915425 1.0 1.0 15 O15118,Q8WTV0 2
Ctla4 inhibitory signaling 0.4786745158910263 0.6472459917187867 0.5174727496591887 1.0 1.0 7 P31751 1
Integrin signaling 0.4777835778216914 0.643255219323483 0.5200585081450104 1.0 1.0 7 P46108,P62993,P12931,Q05397 4
Platelet aggregation plug formation 0.4777835778216914 0.643255219323483 0.5200585081450104 1.0 1.0 7 P46108,P62993,P12931,Q05397 4
Hedgehog ligand biogenesis 0.5713894911205785 0.642045679876174 0.5208435238747486 1.0 1.0 41 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 20
Antigen presentation folding assembly and peptide loading of class i mhc 0.4815406776874131 0.6298895579665669 0.528766845207453 1.0 1.0 16 Q9NZ08,P10321,P30511,Q9Y6B6 4
Orc1 removal from chromatin 0.6031140630866056 0.619046959857441 0.5358854233129335 1.0 1.0 52 P33991,P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,Q14566,O00487,P20618,P33993,Q9Y619,O00231,P49736,P62191,P25787,P28074,O00233,P61289 26
Recruitment of numa to mitotic centrosomes 0.5621140502831611 0.6161376829152729 0.537803653279294 1.0 1.0 40 P06493,Q15154,P17252,O43805,Q9UGJ1,Q13561,Q96CS2,Q9BSJ2,Q68CZ6,Q14203,P43034,O94927,Q9BVA1,P68371,P62258,O95684,Q15691,O75935,P53350,P61163,P23258,Q9H6D7,Q96CW5 23
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.5950923838159181 0.6131377824409823 0.5397852397182819 1.0 1.0 50 Q96GD4,P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q96DE5,Q9UJX3,Q99436,P49721,O75832,O00487,P20618,O00231,P53350,O00233,P62191,P25787,P28074,Q9UJX4,P61289 25
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.4480810031952058 0.6075782146967554 0.5434672532483442 1.0 1.0 8 P31751 1
Auf1 hnrnp d0 binds and destabilizes mrna 0.5662863009375259 0.6046927597407078 0.5453831597852998 1.0 1.0 42 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 20
Signaling by fgfr1 in disease 0.4618189549598194 0.6046212518300954 0.5454306826844104 1.0 1.0 12 P19174,O95684,O94905,O95429 4
Downstream signaling events of b cell receptor bcr 0.5695706846584865 0.6042777941448791 0.5456589672506447 1.0 1.0 43 P55036,P60900,P28072,O43242,Q15008,Q14997,Q08209,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 22
Signaling by insulin receptor 0.4827010158792008 0.6024388334785635 0.5468820670886778 1.0 1.0 18 P27361,P31751,P36543,Q93050,P21281,Q9Y487 6
Fceri mediated nf kb activation 0.5680138459320208 0.5975004681851677 0.5501732945054041 1.0 1.0 43 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 21
Cyclin a cdk2 associated events at s phase entry 0.5689741870122265 0.5870587681028868 0.5571642380872905 1.0 1.0 44 P55036,P60900,P28072,O43242,Q15008,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P31751,P25787,P11802,P28074,O00233,P61289 22
Shc related events triggered by igf1r 0.7741559953434262 0.5852593110128712 0.5583733696095614 1.0 1.0 2 P08069 1
Signaling by fgfr4 in disease 0.774155995343422 0.5852593110128603 0.5583733696095687 1.0 1.0 2 P19174 1
Egfr transactivation by gastrin 0.7741559953434218 0.5852593110128587 0.5583733696095698 1.0 1.0 2 P17252 1
Signaling by the b cell receptor bcr 0.5717383220013346 0.5844899873455724 0.5588906997437879 1.0 1.0 45 P55036,P60900,P62993,P28072,O43242,Q15008,Q14997,Q08209,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 23
Arms mediated activation 0.5732428918599338 0.5762271046805097 0.5644616868541976 1.0 1.0 3 P46108 1
Transport of vitamins nucleosides and related molecules 0.4439163759506068 0.5712983543710841 0.5677974170426838 1.0 1.0 9 Q9Y289,Q8TB61,P12236,O00400 4
Uptake and function of diphtheria toxin 0.5099009900989935 0.5703338664691343 0.5684512751680255 1.0 1.0 4 P07900,P08238,Q16881 3
Regulation of runx2 expression and activity 0.5680692226272716 0.5687051277816167 0.5695562673367354 1.0 1.0 45 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,P49841,P62333,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 22
Transcriptional regulation by runx3 0.5603183291523633 0.5642316638717414 0.5725964812884419 1.0 1.0 43 P55036,P60900,P28072,O43242,Q15008,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,P25440,O00231,P62191,P25787,P28074,O00233,P61289 20
Regulation of hmox1 expression and activity 0.5735486347214562 0.563557366057699 0.5730554086740924 1.0 1.0 47 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,P09601,P62333,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 22
Mrna capping 0.4735887988994419 0.5451833543280038 0.5856274186917114 1.0 1.0 19 P18074,P35269,P13984,P19388,Q92759 5
Activation of bh3 only proteins 0.4434958515202937 0.5366241769688526 0.5915272403836407 1.0 1.0 11 P31946,P31751,P27348,P63104 4
Unblocking of nmda receptors glutamate binding and activation 0.5034268181553833 0.5329052255178157 0.5940991877795982 1.0 1.0 5 P07196,Q13555 2
Ras activation upon ca2 influx through nmda receptor 0.5034268181553833 0.5329052255178157 0.5940991877795982 1.0 1.0 5 P07196,Q13555 2
Hiv elongation arrest and recovery 0.4836349982876105 0.5278744606061979 0.5975864718820536 1.0 1.0 23 P35269,P18615,Q15369,P13984,Q8IXH7,P19388 6
Vitamin b5 pantothenate metabolism 0.4994514955676457 0.5183660238212752 0.6042029154774489 1.0 1.0 5 Q9Y289,P49327,Q9NRN7 3
Signaling by fgfr in disease 0.484712761179614 0.5174030942709414 0.6048748001203919 1.0 1.0 24 P19174,P35269,P13984,P30876,O95684,P19388,O95429 7
Long term potentiation 0.4496386455463677 0.5156770026223978 0.6060800192920199 1.0 1.0 6 P07196,Q15334,Q13555 3
Phase ii conjugation of compounds 0.5047548267216929 0.5148170798477385 0.6066808489457349 1.0 1.0 30 P21964,O15217,Q9NUJ1,P78417,Q8TB61 5
Interleukin 1 signaling 0.5618469497925697 0.5141076856123276 0.6071767043083729 1.0 1.0 47 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,P09429,O00487,P20618,O00231,P63208,P62191,P25787,P28074,O00233,P61289 23
Cyclin d associated events in g1 0.4344883021101021 0.5118514007216586 0.6087550134211361 1.0 1.0 10 P12931,Q00534,Q13309,P11802,P63208,P30153,P30154 7
Cargo concentration in the er 0.4549435506461006 0.5089001735635299 0.6108221983140596 1.0 1.0 16 Q15363,Q96PC5,Q9Y6B6 3
Hedgehog off state 0.5758906370745875 0.5039556666011205 0.6142925312165015 1.0 1.0 52 P55036,P60900,P28072,O43242,Q15008,P17252,Q14997,Q9UL46,P28070,P49720,P49841,P62333,Q99436,P49721,O75832,Q9BVA1,O00487,P20618,P68371,P10644,O00231,P62191,P48729,P25787,P28074,O00233,P61289 27
Glycerophospholipid biosynthesis 0.5217363417255229 0.5002281782414976 0.6169144193239078 1.0 1.0 36 Q9HCL2,Q9NUQ2,Q9NPH0,Q9UG56,P35790,Q8WWI5,Q8IV08,Q8NCC3 8
Protein protein interactions at synapses 0.4418337330373567 0.497393061236818 0.6189118977265609 1.0 1.0 13 O95197 1
Mapk6 mapk4 signaling 0.5674830371183945 0.4963606737234992 0.6196399658909044 1.0 1.0 50 P06493,P55036,P60900,P28072,O43242,Q15008,P17252,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,Q9HCE1,O00231,P62191,P25787,P28074,O00233,P61289 23
Signaling by notch4 0.5438619172996702 0.4945145204483315 0.6209428540974637 1.0 1.0 43 P55036,P60900,P28072,P28066,O43242,Q15008,Q9UL46,P28070,P49720,P62333,Q99436,P63104,O75832,P49721,O00487,P20618,O00231,P63208,P62191,P25787,P28074,O00233,P61289 23
Sulfur amino acid metabolism 0.4340194481193397 0.4939117380067839 0.6213685144209657 1.0 1.0 11 Q13126,Q9UBX3 2
Fgfr1 mutant receptor activation 0.4331432242078307 0.4900061064800678 0.6241295777448694 1.0 1.0 11 O94905,O95684,O95429 3
Abc family proteins mediated transport 0.5753383201641386 0.4882172491131092 0.6253959679596877 1.0 1.0 53 P55036,P60900,Q9BUN8,P28072,P56589,O43242,P40855,Q15008,O75477,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,Q9NUT2,O00487,P20618,O94905,O00231,O75027,P62191,P25787,P08183,P28074,O00233,P61289 28
Erks are inactivated 0.4413195236562429 0.4813737055774756 0.6302509212725496 1.0 1.0 6 P30154 1
Signaling by ptk6 0.4332299292231806 0.474835725956122 0.6349040665986534 1.0 1.0 12 P46108,Q96JJ3 2
Activation of ampk downstream of nmdars 0.418970508263322 0.4739489807863535 0.6355362896214174 1.0 1.0 8 Q9Y478,Q9BVA1,P54619,P68371 4
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.4189504373177878 0.473859641278564 0.6356000007853755 1.0 1.0 8 P68036,A0AVT1,Q16763,Q93009,P61086,P45974,Q93008 7
Selective autophagy 0.5099124721642552 0.4647173611751163 0.6421338739520579 1.0 1.0 35 Q9NS69,Q8N4H5 2
Dcc mediated attractive signaling 0.4793244030285278 0.4616573490081974 0.6443270614628593 1.0 1.0 4 P60953,P12931,Q05397 3
Notch4 activation and transmission of signal to the nucleus 0.7299185098952262 0.4578070587252195 0.6470910640839691 1.0 1.0 2 P63104 1
Nrif signals cell death from the nucleus 0.7299185098952261 0.4578070587252182 0.64709106408397 1.0 1.0 2 Q13501 1
Tcr signaling 0.5544605630139701 0.4565097851491755 0.6480234359867971 1.0 1.0 49 P55036,P60900,P28072,O43242,Q15008,P50552,Q14997,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,P19174,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 23
Glutathione conjugation 0.4425032432100058 0.4544484339792513 0.6495060986571646 1.0 1.0 16 O15217,P78417 2
Runx3 regulates p14 arf 0.7267171129220206 0.4491284692750318 0.6533389843920816 1.0 1.0 2 P25440 1
Fc epsilon receptor fceri signaling 0.5650263586158824 0.4464234024136871 0.6552914312578288 1.0 1.0 53 P55036,P60900,P62993,P28072,O43242,Q15008,Q14997,Q08209,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,P19174,O00487,P20618,P27361,O00231,P62191,P25787,P28074,O00233,P61289 25
Regulation of plk1 activity at g2 m transition 0.5181856707893794 0.4299672150513435 0.6672194900224433 1.0 1.0 40 P06493,Q13561,P68371,O75935,P53350,Q15691,Q15154,Q96CS2,Q68CZ6,P61163,Q14203,Q9H6D7,O95684,P43034,P63208,P17252,O43805,O94927 18
Plasma lipoprotein assembly remodeling and clearance 0.4486542862886441 0.4219098896566778 0.673090791185325 1.0 1.0 20 Q8WTV0,Q9BU23,O15118,P61916,Q9Y6B6 5
Clec7a dectin 1 signaling 0.545072509097101 0.4188480068022042 0.6753272173607199 1.0 1.0 49 P55036,P60900,P28072,O43242,Q15008,Q14997,Q08209,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 22
Ire1alpha activates chaperones 0.4646290202132275 0.4172908544338886 0.6764656771510977 1.0 1.0 25 P43307,O14773,Q9Y5M8,Q9NWM8,P49748,P51858,O95070 7
Pentose phosphate pathway 0.4058931340219084 0.4166999520633877 0.676897889433584 1.0 1.0 8 P11413,Q96G03 2
The phototransduction cascade 0.5219848464062784 0.4149562684363756 0.6781739171888219 1.0 1.0 3 P49356 1
Diseases of immune system 0.7089639115250358 0.4024869517119044 0.6873256893422024 1.0 1.0 2 P09429 1
Signaling by erbb4 0.404843617024388 0.3973692092517293 0.691095217784006 1.0 1.0 9 Q92542,P62993,P46934 3
Hiv transcription elongation 0.4718194043981599 0.3913754935437121 0.6955197039271424 1.0 1.0 29 P18074,P35269,P18615,Q15369,P13984,Q8IXH7,P19388,Q92759 8
Egr2 and sox10 mediated initiation of schwann cell myelination 0.3997405990293066 0.3904799554639022 0.6961816745113825 1.0 1.0 8 Q9NR77 1
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.4780189291705216 0.3892643656406169 0.6970805936941342 1.0 1.0 31 Q13561,P68371,O43237,O75935,P61163,P47756,Q9NZ32,Q14203,Q9UJW0,O60884,Q13451,Q9BVA1,Q15185 13
Vegfr2 mediated cell proliferation 0.4581210398415652 0.3746232158837305 0.7079407046312822 1.0 1.0 5 P17252 1
Synthesis of ip3 and ip4 in the cytosol 0.6976135040745182 0.3740492428654023 0.7083676803804333 1.0 1.0 2 P19174 1
P130cas linkage to mapk signaling for integrins 0.452541033050461 0.3735423115923758 0.7087448603456439 1.0 1.0 4 P46108,Q05397 2
Interleukin 1 family signaling 0.5333308803896984 0.372943727765282 0.7091903259494239 1.0 1.0 49 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,P09429,O00487,P20618,O00231,P63208,P62191,P25787,P28074,O00233,P61289 23
Maturation of sars cov 2 nucleoprotein 0.4511319360585764 0.3691181497693127 0.7120396611629707 1.0 1.0 4 P49841 1
Intra golgi traffic 0.4299913438103522 0.3593394774783846 0.7193411450126332 1.0 1.0 19 Q9UP83,O00461,O95249 3
Apc c mediated degradation of cell cycle proteins 0.561917636705799 0.359202601393959 0.7194435306896634 1.0 1.0 59 Q96GD4,P06493,P55036,P60900,Q13257,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q96DE5,Q9UJX3,Q99436,P49721,O75832,O00487,P20618,O00231,P53350,O00233,P62191,P25787,P28074,Q9UJX4,P61289 27
Switching of origins to a post replicative state 0.5700743406229025 0.3540217802992629 0.7233225606031584 1.0 1.0 62 P33991,P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q96DE5,Q9UJX3,Q99436,P49721,O75832,Q14566,O00487,P20618,P33993,Q9Y619,O00231,P49736,O00233,P62191,P25787,P28074,Q9UJX4,P61289 28
Elastic fibre formation 0.4954876273653604 0.3412767254101736 0.7328952677145468 1.0 1.0 3 P55081,P06756 2
Molecules associated with elastic fibres 0.4954876273653604 0.3412767254101736 0.7328952677145468 1.0 1.0 3 P55081,P06756 2
Activation of kainate receptors upon glutamate binding 0.4420500873616791 0.3411549182431956 0.7329869595852201 1.0 1.0 4 Q12959,Q9UBI6,Q15334 3
C type lectin receptors clrs 0.5348814560740445 0.3299696542800152 0.7414228915005778 1.0 1.0 53 P55036,P60900,P28072,O43242,Q15008,P17252,Q14997,Q08209,Q9UL46,P28070,P49720,P62333,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 23
Activation of atr in response to replication stress 0.4258444393038284 0.3294935723522843 0.7417826514950261 1.0 1.0 20 P33991,Q9Y619,Q14566 3
Copi mediated anterograde transport 0.5420895300763575 0.3094898514949395 0.7569489308295596 1.0 1.0 57 P24390,P49755,Q13561,O75935,P84085,P35606,Q14203,P62820,Q9UJW0,O15498,O95249,Q9UP83,Q9Y3B3,Q9BVK6,Q15363 15
Diseases of glycosylation 0.4137471031537785 0.3088289412167002 0.7574516526413095 1.0 1.0 18 Q8NCH0,P16278,P10619,Q9BT22 4
Generation of second messenger molecules 0.4362478211118792 0.305149267762805 0.7602524691757417 1.0 1.0 5 P19174 1
Role of lat2 ntal lab on calcium mobilization 0.6673457508731073 0.303898897358746 0.7612049178683027 1.0 1.0 2 P62993 1
Interleukin receptor shc signaling 0.6673457508731073 0.303898897358746 0.7612049178683027 1.0 1.0 2 P62993 1
Ca2 pathway 0.3953359656895222 0.3030320063593255 0.7618654701172798 1.0 1.0 7 P17252,Q08209 2
Fatty acyl coa biosynthesis 0.4070757265332768 0.2962436330084805 0.7670440291348108 1.0 1.0 17 P50897,Q9UKU0 2
Synthesis of very long chain fatty acyl coas 0.3761171369681425 0.2947130163558706 0.7682131189767547 1.0 1.0 8 Q9UKU0 1
Cilium assembly 0.5599408888466204 0.294086020942738 0.7686921724944489 1.0 1.0 64 P06493,Q9UPT5,P17252,O43805,A0AVF1,O43924,Q13561,Q9NQ48,Q96CS2,Q92973,Q68CZ6,Q14203,P43034,P78371,Q8TAG9,O94927,O60645,O95684,Q15691,O75935,P53350,P36405,P61163,Q9H6D7,P50991,Q10713 26
Diseases associated with n glycosylation of proteins 0.4305495192480124 0.287933787312862 0.7733974230723613 1.0 1.0 5 Q9BT22 1
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.6577415599534331 0.283462673815354 0.7768221907056243 1.0 1.0 2 P12814 1
Interleukin 15 signaling 0.6542491268917376 0.2762573617259206 0.7823504024129617 1.0 1.0 2 P62993 1
Interferon alpha beta signaling 0.3812378698955083 0.2753083882830158 0.7830793204761652 1.0 1.0 11 P10321,P30511 2
Metabolism of steroids 0.4997701151618184 0.2727719574540792 0.7850285170974987 1.0 1.0 47 Q53GQ0,Q16850,P04062,P48449,O95772,Q9HCL2,P38435,Q9BWD1,Q15126,P14324,Q14739,P37268,Q15125,Q15392,Q15800,P30536,Q9Y6B6 17
Lysosome vesicle biogenesis 0.3921256177961366 0.2655191308980222 0.7906095742652299 1.0 1.0 15 P20645,Q10567,P50570,O43633 4
Runx1 regulates transcription of genes involved in differentiation of hscs 0.4844800390625955 0.264486985457978 0.7914046919716218 1.0 1.0 43 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 20
Grb2 sos provides linkage to mapk signaling for integrins 0.4141998997052473 0.2618172577916041 0.7934623332596773 1.0 1.0 4 P62993,Q05397 2
Regulation of mecp2 expression and activity 0.3745199674062971 0.250414345186227 0.8022669370930005 1.0 1.0 11 Q96GD4,Q13555,Q14739,P17252 4
Negative regulation of mapk pathway 0.377443246255032 0.2487791716162158 0.803531603313093 1.0 1.0 12 P30086,P30154,P27361 3
Signaling by activin 0.6399883585564773 0.2481098561885537 0.8040494098708462 1.0 1.0 2 P27361 1
Signaling by nodal 0.6399883585564773 0.2481098561885537 0.8040494098708462 1.0 1.0 2 P27361 1
Response of eif2ak1 hri to heme deficiency 0.4564774381368212 0.2474459187177636 0.8045631408100962 1.0 1.0 3 P08243,P20042 2
Processing and activation of sumo 0.6350407450523958 0.2388286571293544 0.8112384479645198 1.0 1.0 2 Q9UBT2 1
Sumo is transferred from e1 to e2 ube2i ubc9 0.6350407450523958 0.2388286571293544 0.8112384479645198 1.0 1.0 2 Q9UBT2 1
Sumo is conjugated to e1 uba2 sae1 0.6350407450523958 0.2388286571293544 0.8112384479645198 1.0 1.0 2 Q9UBT2 1
Fgfr2 alternative splicing 0.3978453361999075 0.2377566780289058 0.8120698211300665 1.0 1.0 19 P13984,P35269,P19388 3
Cd28 dependent vav1 pathway 0.409845616079227 0.2287751173467191 0.8190437074119619 1.0 1.0 5 Q13177,P60953,P62993,P63000 4
Dag and ip3 signaling 0.3644440232192369 0.2263249705967454 0.8209486784772313 1.0 1.0 10 P17252,Q13555,P19174,P52292 4
Transcriptional regulation by runx2 0.5175978989192539 0.2244425389132582 0.8224129735951109 1.0 1.0 57 P06493,P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,P49841,Q99436,P49721,O75832,O00487,P20618,P27361,O00231,P62191,P31751,P25787,P11802,P28074,O00233,P61289 25
Ripk1 mediated regulated necrosis 0.363477246207709 0.2229162493612854 0.8236006894109302 1.0 1.0 10 O00560,Q9UNE7,Q13546,P49327,Q14254,Q16543,P07900,Q8WUM4,O75955 9
Biological oxidations 0.4810733602221339 0.219663276787567 0.8261334069814184 1.0 1.0 46 Q16850,Q6QHF9,P21964,O43169,O15217,Q9NUJ1,P78417,Q8TB61 8
Collagen biosynthesis and modifying enzymes 0.3648699511580745 0.2160460684451058 0.8289518379925354 1.0 1.0 11 O15460 1
Copi dependent golgi to er retrograde traffic 0.4951277831264175 0.213195590346102 0.8311744076024039 1.0 1.0 51 P24390,O15260,P49755,Q9P2W9,P84085,P35606,Q9H0B6,Q9NS87,Q9H0H5,P62820,Q9NQT8,Q9Y3B3,P52732,Q9BVK6,Q15363 15
Pcp ce pathway 0.4974983865837153 0.2105228342470625 0.8332596318181344 1.0 1.0 52 P55036,P60900,P28072,O43242,Q15008,P17252,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 21
Irak1 recruits ikk complex 0.6178696158323619 0.2085805444388234 0.8347756998049447 1.0 1.0 2 O15111 1
Antigen processing cross presentation 0.5048041618088758 0.2033055704608333 0.8388962018517176 1.0 1.0 55 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q9UIQ6,Q99436,P49721,O75832,P09429,O00487,P20618,O00231,P10321,P01889,P62191,P30511,P25787,P28074,O00233,P61289 25
Ldl clearance 0.3660008830599811 0.1970555815137567 0.8437840426369383 1.0 1.0 13 O15118 1
Telomere c strand synthesis initiation 0.3971568938368559 0.1953325537904557 0.8451326136457982 1.0 1.0 5 Q14181,P49643 2
Uch proteinases 0.4793335776654705 0.1930792938652919 0.8468968686310945 1.0 1.0 48 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,O00231,P62191,P25787,P28074,O00233,P61289 20
Visual phototransduction 0.3474299825494569 0.190847895071475 0.8486447634223664 1.0 1.0 8 P09455,P49356 2
Degradation of beta catenin by the destruction complex 0.4803517701955184 0.1861567868321676 0.8523218106622379 1.0 1.0 49 P55036,P60900,P28072,O43242,Q15008,Q14997,Q9UL46,P28070,P49720,P49841,P62333,Q99436,P49721,O75832,P30154,O00487,P20618,O00231,P62191,P48729,P25787,P28074,O00233,P61289 24
Signaling by vegf 0.4270226242144697 0.180804306988603 0.856521182341663 1.0 1.0 33 P19174,Q96JJ3,P31751,Q9UQB8,P17252,Q7L576 6
Suppression of phagosomal maturation 0.3525641025640949 0.1667669624640558 0.8675534147378372 1.0 1.0 6 P52294,P20339,Q9UI12,Q9H267,Q14974 5
Initiation of nuclear envelope ne reformation 0.3729633316013179 0.1656913356663654 0.8683998649415441 1.0 1.0 18 Q8IXJ6,Q14739,Q86XL3 3
Costimulation by the cd28 family 0.362620425250219 0.1644099895583676 0.8694084000520679 1.0 1.0 15 P31751 1
Shc1 events in erbb2 signaling 0.4120622970521553 0.1643559841626316 0.8694509118538623 1.0 1.0 3 P17252 1
Parasite infection 0.3917300107888646 0.1625091388074232 0.8709049322085551 1.0 1.0 24 P27361,P62993,Q96JJ3,P46108,Q9UQB8,Q7L576 6
Diseases of mitotic cell cycle 0.3582266603592253 0.1610258369747848 0.8720730512156734 1.0 1.0 14 Q9UJX3,Q96DE5,Q00534,P11802 4
Signaling by erbb2 ecd mutants 0.3818243915260001 0.1579833097338666 0.8744699504499567 1.0 1.0 5 P62993,P19174 2
Signaling by erbb2 in cancer 0.3818243915260001 0.1579833097338666 0.8744699504499567 1.0 1.0 5 P62993,P19174 2
Signaling by hedgehog 0.5024451998361038 0.1566678012449436 0.8755066645439473 1.0 1.0 59 P55036,P60900,P28072,O43242,Q15008,P17252,Q14997,Q9UL46,P28070,P49720,P49841,P62333,Q99436,P49721,O75832,Q9BVA1,O00487,P20618,P68371,P10644,O00231,P62191,P48729,P25787,P28074,O00233,P61289 27
Displacement of dna glycosylase by apex1 0.4061135371179011 0.1552220517244181 0.87664626421928 1.0 1.0 3 P78549,P27695 2
Sema4d induced cell migration and growth cone collapse 0.3500437190323652 0.1537029293851537 0.8778439749168769 1.0 1.0 7 P60660,Q7Z406,P61586,Q13464,P35579,O75116 6
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.339162330548149 0.1533710519838446 0.8781056719484666 1.0 1.0 9 Q96PU5,P27361 2
Formation of incision complex in gg ner 0.3621486969475372 0.152638795047206 0.8786831294394133 1.0 1.0 16 Q92759,Q9UGN5 2
Cytoprotection by hmox1 0.5276507349681072 0.148131572440846 0.882238933098088 1.0 1.0 68 P55036,P60900,P30519,P28072,O43242,Q14997,O43819,Q9UL46,P28070,P13073,P09601,Q99436,P49721,O75832,O00487,P20618,O00231,P14854,O75880,P00403,P28074,O00233,P61289 23
Basigin interactions 0.3472753476243189 0.1457489554409278 0.884119573124956 1.0 1.0 7 P53985 1
Platelet homeostasis 0.3376284898643285 0.1385475815471263 0.8898076675407247 1.0 1.0 10 P16615 1
Formyl peptide receptors bind formyl peptides and many other ligands 0.3935211882409742 0.1374272949097134 0.8906930575065541 1.0 1.0 3 Q9NRV9 1
Formation of rna pol ii elongation complex 0.4256681208988269 0.1370989733523759 0.890952563953193 1.0 1.0 37 P18074,Q92541,P35269,P18615,Q15369,P13984,Q8IXH7,P19388,Q92759 9
Synthesis of pips at the plasma membrane 0.343631594287391 0.1355040726586666 0.8922133444411142 1.0 1.0 7 P61106,O00443,P20339,Q01968,O00459,Q9BTU6 6
Phospholipid metabolism 0.4659383194529082 0.1329700707127474 0.894217050386753 1.0 1.0 50 Q9HCL2,Q9NUQ2,Q9NPH0,Q9UG56,P35790,Q96N66,Q8WWI5,Q8IV08,Q8NCC3 9
Synthesis of pips at the golgi membrane 0.3287842558282822 0.1319691236346761 0.8950087138790896 1.0 1.0 8 Q10713,Q9BTU6,O00443 3
Inositol phosphate metabolism 0.3388694638694577 0.1292285230723835 0.8971768272891223 1.0 1.0 6 P19174,Q01968,Q96PE3,Q9NPH2,Q9BW91 5
Inla mediated entry of listeria monocytogenes into host cells 0.3825327510916997 0.1235771860941057 0.9016500568632342 1.0 1.0 3 P12931,O60716 2
Interferon gamma signaling 0.3482085392116769 0.1211003840383141 0.9036115249973048 1.0 1.0 15 P10321,P30511 2
Tp53 regulates transcription of dna repair genes 0.4123519576917038 0.1175306087151438 0.9064395898757523 1.0 1.0 35 P18074,Q9BXW9,P35269,P18615,Q15369,P13984,P30876,Q8IXH7,P19388,Q92759 10
Signaling by erbb2 0.3458154696672173 0.1143242333256874 0.9089807730222046 1.0 1.0 15 P17252,P62993,P19174,P31751 4
Response to elevated platelet cytosolic ca2 0.4173533345659533 0.1134476124388427 0.9096756940630712 1.0 1.0 37 Q9UEU0,Q9NZJ7,O94919,P07602,Q15833,Q8NBX0,Q92520,O43852,P17252,Q9NUQ9 10
Mrna decay by 3 to 5 exoribonuclease 0.3403239139398689 0.1082154056413888 0.9138248247857376 1.0 1.0 14 Q6PGP7,Q969T7 2
Dna damage recognition in gg ner 0.3594587162491488 0.1065432927899859 0.9151513081814155 1.0 1.0 20 Q9UBW8,Q9UGN5,Q92905,Q9BT78,Q9UNS2,Q7L5N1,Q99627 7
Apc c cdc20 mediated degradation of cyclin b 0.3325197831415177 0.1048997828972975 0.9164553312417704 1.0 1.0 12 P06493,Q96DE5,Q9UJX3 3
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.3389553638599387 0.1044559412745726 0.916807530716638 1.0 1.0 14 P78371 1
Ikk complex recruitment mediated by rip1 0.3647743813682643 0.1043733669545247 0.9168730573170896 1.0 1.0 3 O15111,P61088 2
Ticam1 rip1 mediated ikk complex recruitment 0.3647743813682643 0.1043733669545247 0.9168730573170896 1.0 1.0 3 O15111,P61088 2
Dna replication pre initiation 0.5028979777651953 0.1043521314338318 0.9168899087912392 1.0 1.0 65 P33991,P55036,P60900,P28072,O43242,Q14997,Q14181,Q9UL46,P28070,P49720,Q99436,P49721,O75832,Q14566,O00487,P20618,P33993,Q9NR33,Q9Y619,O00231,Q07864,P49736,P62191,P28074,O00233,P61289 26
Synthesis of ip2 ip and ins in the cytosol 0.3386721025043634 0.1032853504924374 0.9177365020470922 1.0 1.0 4 Q01968,Q96PE3,Q9NPH2 3
Regulation of kit signaling 0.33817252670439 0.1025311748331132 0.9183350692950067 1.0 1.0 4 P17252 1
Beta catenin independent wnt signaling 0.4800882024555487 0.1018971556996288 0.9188383076355692 1.0 1.0 58 P55036,P60900,P28072,O43242,Q15008,P17252,Q14997,Q08209,Q9UL46,P28070,P49720,Q99436,P49721,O75832,O00487,P20618,Q9HCE1,O00231,P62191,P25787,P28074,O00233,P61289 23
Glutathione synthesis and recycling 0.3261060277126317 0.0974492958677814 0.9223695985389102 1.0 1.0 6 P48507 1
Apc cdc20 mediated degradation of nek2a 0.3322317278365396 0.0952169243464199 0.924142527378118 1.0 1.0 13 Q9UJX3,Q96DE5,Q13257 3
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3322317278365396 0.0952169243464199 0.924142527378118 1.0 1.0 13 Q9UJX3,Q96DE5,Q13257 3
Processive synthesis on the lagging strand 0.3314430163267083 0.0931261815831402 0.9258033179184336 1.0 1.0 13 P35244,Q14181,P49643,P09884 4
Prevention of phagosomal lysosomal fusion 0.3522561863173168 0.0930696228072568 0.9258482501511957 1.0 1.0 3 P20339,Q9H267 2
Transcription of the hiv genome 0.3987132655407882 0.0894324433387407 0.9287382407098264 1.0 1.0 34 P18074,P35269,P18615,Q15369,P13984,Q8IXH7,P19388,Q92759 8
Golgi associated vesicle biogenesis 0.3845171010466756 0.0862943678150668 0.931232415608727 1.0 1.0 30 Q9Y5X1,P50570,O00443,O00203,Q99523,O14976,O60749,Q14677,Q10567,Q9Y5X3,P55327,Q9BXS5 12
Ptk6 regulates proteins involved in rna processing 0.5061117578579729 0.0838587575020245 0.9331687307559208 1.0 1.0 2 P23246 1
Fcgamma receptor fcgr dependent phagocytosis 0.3960692693704709 0.0826140158745685 0.9341584563177494 1.0 1.0 34 P19174,P27361,P62993,Q96JJ3,P46108,Q9UQB8,Q7L576,Q8IV08 8
Pyrimidine salvage 0.3228520838806095 0.0812542996186875 0.9352397173801504 1.0 1.0 4 Q9BZX2 1
Mitotic g1 phase and g1 s transition 0.5372434450322144 0.0810213586066894 0.9354249666320014 1.0 1.0 79 P06493,P33991,P55036,P60900,P31350,P28072,O43242,Q15008,Q14181,Q9UL46,P28070,P00374,P49720,P62333,P49721,Q99436,O75832,P30154,Q14566,P20618,P33993,Q9NR33,O00487,Q9Y619,O00231,P49643,Q00534,P49736,Q07864,P62191,P31751,P25787,P11802,P28074,O00233,P61289 36
G alpha i signalling events 0.3788225500184558 0.0800576273147067 0.9361914230336714 1.0 1.0 29 Q9NZJ7,P07602,P52292,P17252,P22466,Q08209,P30154 7
Notch3 activation and transmission of signal to the nucleus 0.4985448195576235 0.0794085385104081 0.936707677340884 1.0 1.0 2 Q92542 1
Noncanonical activation of notch3 0.4985448195576235 0.0794085385104081 0.936707677340884 1.0 1.0 2 Q92542 1
Complex i biogenesis 0.3814279478736201 0.0784180569697373 0.937495510375217 1.0 1.0 30 O43676,Q86Y39,Q9Y6M9 3
Activation of the ap 1 family of transcription factors 0.3318777292576282 0.0782706059732968 0.9376127987474592 1.0 1.0 3 P28482,P27361 2
Mtor signalling 0.3330779463261666 0.0721010850851281 0.9425214627019264 1.0 1.0 16 P31751,Q9Y478,Q15382,P54619 4
Rac2 gtpase cycle 0.4079669184883305 0.0718885298958553 0.9426906182489488 1.0 1.0 39 O15173,Q13505,P50402,Q7L576,Q9H0H5,Q86XL3,Q9Y512,Q14739 8
Nrcam interactions 0.4810826542491254 0.0706507573174093 0.9436757128107488 1.0 1.0 2 Q15334 1
Ionotropic activity of kainate receptors 0.4810826542491254 0.0706507573174093 0.9436757128107488 1.0 1.0 2 Q15334 1
Syndecan interactions 0.3175353560296139 0.0698453925579396 0.9443167173360144 1.0 1.0 7 P17252,P06756 2
Nef and signal transduction 0.4790454016298004 0.0697571320073167 0.9443869677205065 1.0 1.0 2 Q13177 1
Activated ntrk2 signals through fyn 0.4790454016298004 0.0697571320073167 0.9443869677205065 1.0 1.0 2 P12931 1
Killing mechanisms 0.4790454016298004 0.0697571320073167 0.9443869677205065 1.0 1.0 2 O14641 1
Condensation of prometaphase chromosomes 0.3121353558926427 0.0692269261953328 0.9448089905117694 1.0 1.0 10 P06493,Q15003,Q9NTJ3,Q9BPX3,Q15021,O95347,P67870,P14635,P68400 9
Runx1 regulates expression of components of tight junctions 0.3136393515067908 0.0683744519617716 0.9454875586058328 1.0 1.0 3 Q16625 1
Wnt mediated activation of dvl 0.311589982527665 0.0678415159440827 0.9459117949273096 1.0 1.0 4 O14641,P67870,P68400 3
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.310917030567676 0.0671376722438193 0.9464721034239978 1.0 1.0 3 Q8NB78,Q9HCE1 2
Triglyceride metabolism 0.315312631548461 0.0648945081645862 0.9482579932287388 1.0 1.0 7 Q9HCL2 1
Protein folding 0.4071686419773576 0.0620731641932945 0.9505045676469768 1.0 1.0 40 Q9UHV9,P04062,Q99471,O95302,P50991,P78371,Q9Y2T2,P61962 8
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.4577997671711276 0.0618560752065447 0.9506774473829588 1.0 1.0 2 P49327 1
Regulation of bach1 activity 0.2972343522561751 0.0617605424954548 0.9507535259989665 1.0 1.0 3 Q13309,P63208 2
Synthesis of pips at the late endosome membrane 0.2963609898107597 0.0614618139474035 0.950991424940952 1.0 1.0 3 Q8NEB9,O00443 2
Amino acids regulate mtorc1 0.3174919063251588 0.0584192245921397 0.9534147019123048 1.0 1.0 13 P21281 1
Rhobtb3 atpase cycle 0.3019801980198033 0.0578210655830999 0.9538911583401732 1.0 1.0 4 P51151,O60664,Q13618 3
Metabolic disorders of biological oxidation enzymes 0.3276796420088353 0.0548098105537236 0.9562899844615228 1.0 1.0 5 P48507 1
Map3k8 tpl2 dependent mapk1 3 activation 0.2973209085614492 0.0534150939891936 0.9574011791171292 1.0 1.0 4 Q02750,O15111,P63208 3
Pi3k akt activation 0.4208381839348063 0.0531609545677363 0.9576036653417576 1.0 1.0 2 O00459 1
Translocation of slc2a4 glut4 to the plasma membrane 0.3929722185229157 0.0514518703149499 0.9589654529411368 1.0 1.0 37 P31946,P27348,P14672,P68371,Q9UPT5,P54619,P31751,Q9UIQ6,P63104,Q96A65,Q8TAG9,Q9Y478,Q9BVA1,O60645 14
Notch2 activation and transmission of signal to the nucleus 0.4039580908032578 0.0507713530539361 0.9595077183775552 1.0 1.0 2 Q92542 1
N glycan trimming and elongation in the cis golgi 0.3856228172293345 0.0489685524413299 0.9609443573776976 1.0 1.0 2 O60476 1
Caspase activation via death receptors in the presence of ligand 0.3646682188591367 0.0476495686182806 0.9619955268226236 1.0 1.0 2 P49327 1
Regulation by c flip 0.3646682188591367 0.0476495686182806 0.9619955268226236 1.0 1.0 2 P49327 1
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.3027453523226424 0.0473924978939072 0.9622004081169706 1.0 1.0 10 Q9UJX3,Q96DE5 2
Signaling by fgfr3 0.3069620913399026 0.0472086572518615 0.9623469277275548 1.0 1.0 7 P19174,P27361 2
Signaling by fgfr1 0.3069620913399026 0.0472086572518615 0.9623469277275548 1.0 1.0 7 P19174,P27361 2
Signaling by fgfr4 0.3069620913399026 0.0472086572518615 0.9623469277275548 1.0 1.0 7 P19174,P27361 2
Cargo recognition for clathrin mediated endocytosis 0.4005101689714205 0.0464881647815102 0.962921167024894 1.0 1.0 40 Q14108,Q9BT78,Q9UNS2,Q9UHD9,P20645,O14657,Q99627 7
Fbxw7 mutants and notch1 in cancer 0.2971478463329434 0.0461875775272766 0.9631607436059868 1.0 1.0 2 P63208 1
Muscle contraction 0.3567377294806125 0.0431115184142145 0.96561263747031 1.0 1.0 27 P16615,Q13555,Q9HD47,P08670,P05023,P17252,Q9NYL9 7
Traf6 mediated nf kb activation 0.3193935976030737 0.0430410413855527 0.9656688178559684 1.0 1.0 5 O15111,P09429 2
Pi metabolism 0.3157014331005067 0.0396328531197067 0.968385835005486 1.0 1.0 15 Q10713,Q8N9F7,P48739 3
Regulation of lipid metabolism by pparalpha 0.3338091103808722 0.0360679694059458 0.971228162413023 1.0 1.0 21 O75448,P37268,Q71SY5,P23786 4
Ca dependent events 0.2940421508158997 0.0357689045111761 0.9714666277985606 1.0 1.0 9 P17252,Q13555,P52292 3
Nr1h2 and nr1h3 mediated signaling 0.3110981648703712 0.0322973049836299 0.9742349583966728 1.0 1.0 5 O00767,P49327,Q8NB78,Q9HCE1 4
Mitochondrial biogenesis 0.3772691323840944 0.0310014250143934 0.9752684032231702 1.0 1.0 35 O75964,P25705,Q13505,O75431,Q9BUR5,P00846,Q9Y478,Q9Y512,P54619 9
Mismatch repair 0.3006421482778831 0.0289044066071204 0.9769408311273924 1.0 1.0 12 P28340,P43246,Q15054,P15927,P20585,P52701,P35244,Q9UQ84,P27694,P12004,Q9Y2S7 11
Ret signaling 0.2873377530313744 0.0288208110914197 0.9770075029224428 1.0 1.0 8 P17252,P19174 2
Signaling by moderate kinase activity braf mutants 0.3100992698091868 0.0279403346011942 0.9777097386302104 1.0 1.0 15 P30086,Q13555,P27361 3
Nucleotide salvage 0.2862169617908967 0.0265839827588142 0.978791548652375 1.0 1.0 8 Q9BZX2,Q08623,P55263 3
Signaling by fgfr2 0.3452842449863883 0.0257018108962848 0.9794951794489604 1.0 1.0 26 P19174,P35269,P27361,P13984,P30876,P19388,P52597 7
Signaling by fgfr 0.3452842449863883 0.0257018108962848 0.9794951794489604 1.0 1.0 26 P19174,P35269,P27361,P13984,P30876,P19388,P52597 7
Interaction between l1 and ankyrins 0.2463599301106567 0.0217564638822803 0.9826422227472762 1.0 1.0 4 Q12955,Q13813,Q01082 3
Signaling by braf and raf1 fusions 0.3413221795887088 0.0177643789032202 0.985826821790556 1.0 1.0 26 P30086,P27361,Q13555,O00203,Q96PU8,Q9NRY5 6
Synthesis of pips at the early endosome membrane 0.2965336440431069 0.0158617183295195 0.9873447105053436 1.0 1.0 5 Q8NEB9,Q96PE3,Q9BTU6,O00443 4
Trans golgi network vesicle budding 0.379163074132815 0.0147895355020794 0.988200088129509 1.0 1.0 38 Q9Y5X1,P50570,O00443,O00203,Q99523,O14976,O60749,P05067,Q14677,P20645,O43633,Q10567,Q9Y5X3,P55327,Q9BXS5 15
Egfr downregulation 0.2784256559766873 0.0118359707651739 0.990556482155592 1.0 1.0 8 P62993,Q9Y6I3,Q99961,P60953,Q14155,Q92783,Q9UBC2 7
Golgi to er retrograde transport 0.4913551756231984 0.0092605031668817 0.9926112931034864 1.0 1.0 74 P24390,Q9NS87,Q10472,O15260,Q13561,P84085,Q9H0B6,Q9H0H5,P62820,Q14203,P43034,P35606,Q9BVK6,Q15363,Q9P2W9,Q9UJW0,O75935,Q9Y3B3,P52732 19
E3 ubiquitin ligases ubiquitinate target proteins 0.3129021445725892 0.0078460616949537 0.9937398127407906 1.0 1.0 19 Q9BUN8,O75381,Q92541 3
Copii mediated vesicle transport 0.3508698267031373 0.0045535509271755 0.996366804573994 1.0 1.0 31 P62820,Q8IUR0,O15498,P53634,Q15363,Q9Y6B6 6
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.2833719612915512 0.0028955803370493 0.9976896643829618 1.0 1.0 11 Q9UJX3,Q96DE5 2