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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/advanced/plot_0.png +3 -0
  3. interpro_active_site/basic/idx2term.json +1 -0
  4. interpro_active_site/basic/plot_0.png +3 -0
  5. interpro_active_site/consensus.joblib +3 -0
  6. interpro_active_site/df_merge.tsv +2 -0
  7. interpro_active_site/metrics.json +7 -0
  8. interpro_active_site/paths.json +1 -0
  9. interpro_active_site/result.tsv +10 -0
  10. interpro_active_site/selections.json +1 -0
  11. interpro_binding_site/advanced/idx2term.json +1 -0
  12. interpro_binding_site/advanced/plot_0.png +3 -0
  13. interpro_binding_site/advanced/plot_1.png +3 -0
  14. interpro_binding_site/basic/idx2term.json +1 -0
  15. interpro_binding_site/basic/plot_0.png +3 -0
  16. interpro_binding_site/basic/plot_1.png +3 -0
  17. interpro_binding_site/consensus.joblib +3 -0
  18. interpro_binding_site/df_merge.tsv +3 -0
  19. interpro_binding_site/metrics.json +7 -0
  20. interpro_binding_site/paths.json +1 -0
  21. interpro_binding_site/result.tsv +6 -0
  22. interpro_binding_site/selections.json +1 -0
  23. interpro_conserved_site/advanced/idx2term.json +1 -0
  24. interpro_conserved_site/basic/idx2term.json +1 -0
  25. interpro_conserved_site/basic/plot_0.png +3 -0
  26. interpro_conserved_site/basic/plot_1.png +3 -0
  27. interpro_conserved_site/basic/plot_2.png +3 -0
  28. interpro_conserved_site/basic/plot_3.png +3 -0
  29. interpro_conserved_site/basic/plot_4.png +3 -0
  30. interpro_conserved_site/basic/plot_5.png +3 -0
  31. interpro_conserved_site/basic/plot_6.png +3 -0
  32. interpro_conserved_site/consensus.joblib +3 -0
  33. interpro_conserved_site/df_merge.tsv +3 -0
  34. interpro_conserved_site/metrics.json +7 -0
  35. interpro_conserved_site/paths.json +1 -0
  36. interpro_conserved_site/result.tsv +49 -0
  37. interpro_conserved_site/selections.json +1 -0
  38. interpro_domain/advanced/idx2term.json +1 -0
  39. interpro_domain/advanced/plot_0.png +3 -0
  40. interpro_domain/advanced/plot_1.png +3 -0
  41. interpro_domain/advanced/plot_2.png +3 -0
  42. interpro_domain/basic/idx2term.json +1 -0
  43. interpro_domain/basic/plot_0.png +3 -0
  44. interpro_domain/basic/plot_1.png +3 -0
  45. interpro_domain/basic/plot_10.png +3 -0
  46. interpro_domain/basic/plot_11.png +3 -0
  47. interpro_domain/basic/plot_12.png +3 -0
  48. interpro_domain/basic/plot_13.png +3 -0
  49. interpro_domain/basic/plot_14.png +3 -0
  50. interpro_domain/basic/plot_15.png +3 -0
interpro_active_site/advanced/idx2term.json ADDED
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interpro_active_site/advanced/plot_0.png ADDED

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interpro_active_site/basic/idx2term.json ADDED
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interpro_active_site/basic/plot_0.png ADDED

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interpro_active_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
2
+ Serine/threonine-protein kinase, active site [IPR008271] 32 53 3.2161531612931675 0.0012992147311257 14.96359223300971 48.092233009708735 -0.2514056606840174 0.5845564538757478 7.386430402173519 10.05983255009733 0.9463339478376924 0.3271131887386243 1.0 0.6706326039375146 0.5100322368593952 0.1089949698292977
interpro_active_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
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+ "type_of_task": "ranksum",
3
+ "signature_size": 3468,
4
+ "annotations_size": 60,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.65
7
+ }
interpro_active_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C066/C066_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,10 @@
 
 
 
 
 
 
 
 
 
 
 
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Serine/threonine-protein kinase, active site [IPR008271] 0.5037802747014247 3.2161531612931675 0.0012992147311257 0.0750388723716073 0.0272695066445356 53 P19525,Q13464,Q99570,Q99986,P28482,P33981,Q2M2I8,Q16513,Q6PHR2,Q13546,Q9H2G2,P78362,P51956,P50750,Q8TD19,P49760,Q96GD4,P27361,P68400,Q00534,P19784,Q13555,P06493,O75116,P11802,O00311,Q13177,P36507,P25098,Q16512,P10398,Q96GX5 32
3
+ Protein-tyrosine phosphatase, active site [IPR016130] 0.6262738518216552 1.8231468147899432 0.0682811577917084 0.9856420412749388 0.1744636273075425 9 P51452,Q9Y217,P10586,Q13614 4
4
+ Ubiquitin-conjugating enzyme, active site [IPR023313] 0.720623454291471 1.7768014990418628 0.0756009051666017 0.9910551987963052 0.1744636273075425 6 P61088,Q16763 2
5
+ Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345] 0.8548759376803226 1.4125697090969422 0.157782280699684 0.999966467768602 0.2309008985849034 2 P18669 1
6
+ ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440] 0.7259088286208917 0.890850852875775 0.3730091895312821 0.999999999999315 0.4271972751470594 2 P53396 1
7
+ Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.7284271284271328 0.8596379584780242 0.3899886440705553 0.999999999999868 0.4333207156339503 3 Q9UBT2,Q8TBC4 2
8
+ L-lactate dehydrogenase, active site [IPR018177] 0.657818811309872 0.6337101776888676 0.5262699816034493 1.0 0.5638606945751242 2 P07195 1
9
+ Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999] 0.562918307543737 0.3298984663707783 0.7414766823514729 1.0 0.7540440837472606 3 Q16881 1
10
+ Glycosyl hydrolases family 31, active site [IPR030458] 0.3600692440854076 0.0310496119318511 0.9752299741257472 1.0 0.9752299741257472 2 P10253 1
interpro_active_site/selections.json ADDED
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+ {"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "DNA/RNA non-specific endonuclease, active site [IPR018524]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAMK4", "CAPN1", "CAPN2", "CASP3", "CDC7", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CKB", "CKMT1A*", "CLK2", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "ENDOG", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GRK2", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IGF1R", "IKBKB", "LDHA", "LDHB", "LONP1", "LONP2", "LYN", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MASTL", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK1", "NEK3", "NEK9", "NME1", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRA", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2A", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "WNK1", "YES1"], "leading_proteins": ["AAK1", "ACLY", "ARAF", "AURKB", "CAMK2G", "CDC7", "CDK1", "CDK4", "CDK6", "CDK9", "CLK2", "CSNK2A1", "CSNK2A2", "DUSP3", "EIF2AK2", "GAA", "GRK2", "LDHB", "MAP2K2", "MAPK1", "MAPK3", "MASTL", "MTMR2", "MTMR6", "NEK3", "NEK9", "PAK2", "PGAM1", "PIK3R4", "PKN1", "PKN2", "PTPRF", "RIPK1", "ROCK1", "ROCK2", "SLK", "SRPK2", "TTK", "TXNRD1", "UBA2", "UBA3", "UBE2N", "UBE2S", "ULK3", "VRK1"]}
interpro_binding_site/advanced/idx2term.json ADDED
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+ {"0": "Protein kinase, ATP binding site [IPR017441]", "1": "IQ motif, EF-hand binding site [IPR000048]"}
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interpro_binding_site/basic/idx2term.json ADDED
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interpro_binding_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
2
+ Protein kinase, ATP binding site [IPR017441] 29 51 2.677940022879034 0.0074076481560649 13.985436893203884 45.86407766990291 -0.192126652758297 0.6147860592683837 6.814446501353132 9.80766348241306 0.8651595242963739 0.3198537516496491 1.0 0.4915345323449248 0.4869206588752693 0.2424994113732815
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+ IQ motif, EF-hand binding site [IPR000048] 6 15 1.9720001667829845 0.0486095874791381 4.902912621359223 10.79368932038835 -0.2273048691062784 0.5134620963427197 2.787853554074696 2.339749173467172 1.002129759133213 0.3214407723554939 1.0 0.3263246311566628 0.257029649424805 0.0029768417379147
interpro_binding_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3468,
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+ "annotations_size": 32,
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+ "title": "Average number of proteins per term",
6
+ "value": 4.90625
7
+ }
interpro_binding_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C066/C066_val_log2fc"}
interpro_binding_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Protein kinase, ATP binding site [IPR017441] 0.4554355269756645 2.677940022879034 0.0074076481560649 0.2117398255925844 0.0776403376572823 51 P19525,Q13464,Q99986,P28482,P33981,Q16513,Q6PHR2,Q9H2G2,P78362,P51956,P50750,O96013,Q16539,P49760,Q96GD4,P27361,P68400,Q00534,P19784,Q13555,P06493,O75116,P11802,O00311,Q13177,P36507,P25098,Q16512,P10398 29
3
+ IQ motif, EF-hand binding site [IPR000048] 0.5691902091034058 1.9720001667829845 0.0486095874791381 0.7970071886337002 0.155550679933242 15 Q15386,Q7Z406,Q12965,Q8IW35,Q8IZT6,Q15051 6
4
+ Beta tubulin, autoregulation binding site [IPR013838] 0.5591876324991012 1.0409082140235828 0.2979181491377618 0.9999878547100608 0.5017568827583357 6 P07437,Q9BVA1,Q13885 3
5
+ PPM-type phosphatase, divalent cation binding [IPR000222] 0.6891323385239474 0.7200198834216041 0.4715127533733267 0.9999999986287889 0.6286836711644357 3 P49593 1
6
+ Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578] 0.4281592613964301 0.0754870807444384 0.9398271762803334 1.0 0.9398271762803334 2 Q9Y697 1
interpro_binding_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARAF", "ARG2", "ASPM", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAMK4", "CAPN1", "CAPN2", "CAPNS1", "CDC7", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CEP97", "CETN2", "CLK2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "GCAT", "GOT1", "GOT2", "GPD2", "GRK2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAPK1", "MAPK14", "MAPK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "NEK1", "NEK3", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["ARAF", "ASPM", "AURKB", "CAMK2G", "CDC7", "CDK1", "CDK4", "CDK6", "CDK9", "CEP97", "CLK2", "CSNK2A1", "CSNK2A2", "EIF2AK2", "GRK2", "IQCB1", "MAP2K2", "MAPK1", "MAPK14", "MAPK3", "MYH14", "MYO1E", "NEK3", "NFS1", "PAK2", "PAK4", "PKN1", "PKN2", "PPM1F", "ROCK1", "ROCK2", "SLK", "SRPK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "UBE3C", "ULK3", "VRK1"]}
interpro_conserved_site/advanced/idx2term.json ADDED
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interpro_conserved_site/basic/idx2term.json ADDED
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1
+ {"0": "Ubiquitin specific protease, conserved site [IPR018200]", "1": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "2": "Chaperonin TCP-1, conserved site [IPR002194]", "3": "DnaJ domain, conserved site [IPR018253]", "4": "Zinc finger, RING-type, conserved site [IPR017907]", "5": "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "6": "Kinesin motor domain, conserved site [IPR019821]"}
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interpro_conserved_site/df_merge.tsv ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
2
+ Proteasome beta-type subunit, conserved site [IPR016050] 3 8 2.556120843401314 0.0105846353113794 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.0010343090391069 0.0001045037164678 6.596771644487082e-05 0.0009470318558772
3
+ Tr-type G domain, conserved site [IPR031157] 1 6 2.2213616024284217 0.0263264795444002 3.3179611650485437 5.747572815533981 -0.75690295516407 0.4176051020773906 1.3981151384057822 0.561178486082269 0.7969183059635996 0.2887489424711709 0.0432957136582515 0.0849171013653387 0.200296332152138 0.0687357084610875
interpro_conserved_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3468,
4
+ "annotations_size": 286,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.765734265734266
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+ }
interpro_conserved_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C066/C066_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
@@ -0,0 +1,49 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.7970599704839694 2.556120843401314 0.0105846353113794 0.9523246405930336 0.0571170886614059 8 P28072,P20618,P28070 3
3
+ Tr-type G domain, conserved site [IPR031157] 0.8217023754411803 2.2213616024284217 0.0263264795444002 0.9995144647534036 0.1000546967324907 6 Q8N442 1
4
+ Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.9000595745836215 2.135359113484653 0.0327316877356804 0.9999264757327178 0.1127862974988507 4 P48735 1
5
+ Mini-chromosome maintenance, conserved site [IPR018525] 0.7579266250881012 1.9430182600912536 0.0520139520882385 0.9999997680702584 0.1582552159280449 6 P49736,P25205,P33991,P33992 4
6
+ Ubiquitin specific protease, conserved site [IPR018200] 0.5511031080288304 1.8612704293545224 0.0627059968620731 0.9999999909533084 0.1673919084310557 15 P51784,P54578,Q9Y4E8,O94966,Q86UV5,Q8NB14,Q9UPU5,Q93008 8
7
+ Profilin conserved site [IPR027310] 0.921811886901328 1.686899714037858 0.0916226370902724 0.9999999999988408 0.2139399090210463 2 P35080 1
8
+ DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.9030582804385456 1.6102035465558655 0.1073534274235266 0.999999999999992 0.2367895964632579 2 P09884 1
9
+ DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.5064915109713399 1.5188206046293573 0.1288076579998451 1.0 0.2650287063881706 14 Q8IX18,Q14562,P18074,Q9H2U1,O60231 5
10
+ Cullin, conserved site [IPR016157] 0.7021399404347446 1.4809509453869485 0.1386196458320649 1.0 0.2786629466509214 5 Q13618,Q13616,Q13617 3
11
+ Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.8369878822850547 1.3391807936094933 0.1805118234140361 1.0 0.3226648843525896 2 P11216 1
12
+ HMG box A DNA-binding domain, conserved site [IPR017967] 0.8369408369408181 1.2638099330073205 0.2062982551106271 1.0 0.3578560010258947 3 P26583,O15347 2
13
+ Chaperonin TCP-1, conserved site [IPR002194] 0.5356599440336333 1.2576273596093992 0.2085265539136609 1.0 0.3578560010258947 8 Q99832,P40227,P17987,P78371,P49368,P50991 6
14
+ DnaJ domain, conserved site [IPR018253] 0.4645780254293233 1.1606334632816913 0.2457909908557285 1.0 0.4016927050556478 12 Q8WXX5,Q9UDY4,P31689,O75190,O60884 5
15
+ DNA ligase, ATP-dependent, conserved site [IPR016059] 0.7905366416618591 1.1494382055172794 0.2503753337429382 1.0 0.4068599173322745 2 P18858 1
16
+ GTP1/OBG, conserved site [IPR006074] 0.7821696480092344 1.1154980065231448 0.2646370722283095 1.0 0.4183369694610291 2 P55039 1
17
+ Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.7959595959595884 1.1092261183037182 0.267332647978983 1.0 0.4183369694610291 3 Q16539,P28482 2
18
+ Fructose-bisphosphate aldolase class-I active site [IPR029768] 0.7792844777841907 1.1038183500091483 0.2696719431764038 1.0 0.4183369694610291 2 P09972 1
19
+ Ribosomal protein L13, conserved site [IPR023563] 0.7772648586266605 1.095650424957736 0.2732317855717516 1.0 0.4183369694610291 2 Q9BYD1 1
20
+ Dynamin, GTPase region, conserved site [IPR019762] 0.7904761904761881 1.088664423797591 0.2763018956960672 1.0 0.420331607282315 3 Q9UQ16,O00429 2
21
+ Tubulin, conserved site [IPR017975] 0.5591876324991012 1.0409082140235828 0.2979181491377618 1.0 0.4437739096531243 6 P07437,Q9BVA1,Q13885 3
22
+ Zinc finger, RING-type, conserved site [IPR017907] 0.3859851701646561 1.0227482898572615 0.306426872902076 1.0 0.45273232244022 20 Q14527,O15344,Q9UBS8,Q8TDB6,P19474 5
23
+ Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892] 0.447711016405616 1.0055686431623012 0.3146231140435835 1.0 0.4614472339305893 11 Q13356,Q9Y3C6,P30414,O43447,Q9H2H8 5
24
+ Ribosomal protein S2, conserved site [IPR018130] 0.7437968840161594 0.9614447145011134 0.336328610718692 1.0 0.4761880329977521 2 Q9Y399 1
25
+ Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.7285054818234321 0.9010385315236252 0.3675678331594381 1.0 0.4994921972624926 2 P82675 1
26
+ Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.7282169648009262 0.899905502062585 0.3681705418465824 1.0 0.4994921972624926 2 Q9UBT2 1
27
+ ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847] 0.7259088286208917 0.890850852875775 0.3730091895312821 1.0 0.5001305102504616 2 P53396 1
28
+ F-actin capping protein, alpha subunit, conserved site [IPR017865] 0.7253317945758828 0.8885898859667465 0.3742235286489468 1.0 0.5001305102504616 2 P47755 1
29
+ D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.5850253987517633 0.8408486187784191 0.4004327460812671 1.0 0.5302026174964926 4 Q13363 1
30
+ ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629] 0.3463445104818171 0.7817722558862397 0.4343484287584731 1.0 0.5545698688612648 21 Q7L014 1
31
+ Kinesin motor domain, conserved site [IPR019821] 0.3868726537669081 0.7176593382541372 0.4729673606301754 1.0 0.5943024152062528 12 Q12756,Q9BW19,O95239,P33176,O00139 5
32
+ XPG conserved site [IPR019974] 0.6794575879976961 0.7129809775773996 0.4758575282595521 1.0 0.5943024152062528 2 P39748 1
33
+ Helix-hairpin-helix motif, class 2 [IPR008918] 0.6794575879976961 0.7129809775773996 0.4758575282595521 1.0 0.5943024152062528 2 P39748 1
34
+ IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.6780150028851745 0.7076144828102162 0.4791846965263393 1.0 0.5958557530718829 2 P12268 1
35
+ S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082] 0.6566647432198551 0.6295609492802763 0.5289818798915733 1.0 0.6493082302531759 2 O43865 1
36
+ Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.6529140219272984 0.6161350952430046 0.5378053609928191 1.0 0.652951565934778 2 P24534 1
37
+ Alpha-D-phosphohexomutase, conserved site [IPR016066] 0.6571428571428537 0.6111772515491012 0.5410822417011971 1.0 0.652951565934778 3 Q96G03,P36871 2
38
+ Alcohol dehydrogenase, zinc-type, conserved site [IPR002328] 0.6396422388920999 0.5693911138144269 0.5690907459592409 1.0 0.6781664722680955 2 Q00796 1
39
+ Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.4744948852353309 0.527788600547234 0.5976460700201947 1.0 0.7005195738761298 5 P42345,P42356,P78527 3
40
+ Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412] 0.3343093523090231 0.4477747491401442 0.654315768741629 1.0 0.7576287848587283 12 Q9P2J5,P26640,P07814,P23381 4
41
+ 14-3-3 protein, conserved site [IPR023409] 0.404026053199452 0.3931954859937458 0.6941751034437165 1.0 0.78783364914644 6 P62258,P31946,P61981 3
42
+ Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131] 0.5626081938834466 0.3276840276180781 0.743150581307878 1.0 0.8270080398990394 2 P12955 1
43
+ Thioredoxin, conserved site [IPR017937] 0.3050516674647013 0.3186157134149275 0.7500179364192396 1.0 0.8282051344243341 12 Q96JJ7 1
44
+ Ras GTPase-activating protein, conserved site [IPR023152] 0.3596997690531165 0.1361922192747367 0.8916693259764976 1.0 0.951557564288352 4 P46940,P21359,Q86VI3 3
45
+ Cyclic nucleotide-binding, conserved site [IPR018488] 0.4039238315060677 0.054558097768517 0.9564905221443916 1.0 0.985631524027109 2 P10644 1
46
+ Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.3659451659451739 0.0395353442854056 0.9684635748696911 1.0 0.985631524027109 3 Q9BXS5,Q9Y2T2 2
47
+ DNA topoisomerase, type IIA, conserved site [IPR018522] 0.374783612233129 0.0371700797020674 0.9703493950582972 1.0 0.985631524027109 2 Q02880 1
48
+ Clathrin adaptor complex, small chain [IPR000804] 0.250866050808308 0.0314671318171371 0.9748970041677198 1.0 0.985631524027109 4 P53680,P56377,P61923 3
49
+ Glycosyl hydrolases family 31, conserved site [IPR030459] 0.3600692440854076 0.0310496119318511 0.9752299741257472 1.0 0.985631524027109 2 P10253 1
interpro_conserved_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Deoxyribonuclease, TatD-related, conserved site [IPR018228]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABR", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ARSA", "ATAD1", "ATAD2", "ATG16L1", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BAZ2A", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTL", "DTX3L", "DTYMK", "DUS2", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IGF1R", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "ING5", "INTS12", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "ITGA6", "ITGAV", "IVD", "KDM2A", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MKRN2", "MLLT10", "MOCS1", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRC2", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIK3C3", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RBBP4", "RCL1", "RDH13", "RDX", "RIDA", "RING1", "RIOK2", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCAP", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLC2A1", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STMN1", "STOM", "STRN", "STRN3", "STRN4", "STX10", "STX12", "STX18", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAF5", "TAP1", "TATDN1", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TM7SF2", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP36", "USP38", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ACLY", "AHCYL1", "ALDOC", "AP1M1", "AP1S2", "AP2S1", "AP3M1", "CAPZA2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "COPZ1", "CTBP1", "CUL1", "CUL2", "CUL3", "DDX46", "DHX16", "DHX36", "DHX40", "DHX8", "DNAJA1", "DNAJA2", "DNAJB4", "DNAJB6", "DNAJC9", "DNM1L", "DNM3", "DRG2", "DTX3L", "EEF1B2", "EPRS", "ERCC2", "FEN1", "GAA", "GUF1", "HLTF", "HMGB2", "HMGB3", "IDH2", "IMPDH2", "IQGAP1", "IQGAP3", "KIF1A", "KIF2A", "KIF4A", "KIF5B", "KIFC1", "LARS", "LIG1", "MAPK1", "MAPK14", "MCM2", "MCM3", "MCM4", "MCM5", "MID1", "MRPL13", "MRPS2", "MRPS5", "MTOR", "NF1", "NKTR", "PEPD", "PFN2", "PGM1", "PGM2", "PI4KA", "POLA1", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PRKAR1A", "PRKDC", "PSMB1", "PSMB4", "PSMB6", "PYGB", "RNF14", "SORD", "TCP1", "TMX3", "TOP2B", "TRIM21", "TUBB", "TUBB2A", "TUBB2B", "UBA2", "USP11", "USP14", "USP15", "USP19", "USP24", "USP38", "USP48", "USP9X", "VARS1", "WARS", "YWHAB", "YWHAE", "YWHAG"]}
interpro_domain/advanced/idx2term.json ADDED
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1
+ {"0": "Protein kinase domain [IPR000719]", "1": "Zinc finger, LIM-type [IPR001781]", "2": "Proteasome component (PCI) domain [IPR000717]"}
interpro_domain/advanced/plot_0.png ADDED

Git LFS Details

  • SHA256: 09d907a53d9514025d98b9417f8cf0d61d425a6b78ac2adef13c93228f3e14bd
  • Pointer size: 131 Bytes
  • Size of remote file: 199 kB
interpro_domain/advanced/plot_1.png ADDED

Git LFS Details

  • SHA256: 2a2cca4858972e27f37d510ca00b87c4a5d95d74f45d3f5b860111b2bb2d1358
  • Pointer size: 131 Bytes
  • Size of remote file: 184 kB
interpro_domain/advanced/plot_2.png ADDED

Git LFS Details

  • SHA256: c8e6ad61fed2dc623aa86cba230490019f4c2ff272e3f77ce6be7d6aafa66ba4
  • Pointer size: 131 Bytes
  • Size of remote file: 195 kB
interpro_domain/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Protein kinase domain [IPR000719]", "1": "Zinc finger, LIM-type [IPR001781]", "2": "Proteasome component (PCI) domain [IPR000717]", "3": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "4": "Ubiquitin specific protease domain [IPR028889]", "5": "Forkhead-associated (FHA) domain [IPR000253]", "6": "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "7": "MPN domain [IPR037518]", "8": "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "9": "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "10": "Importin-beta, N-terminal domain [IPR001494]", "11": "Zinc finger, RING-type [IPR001841]", "12": "DnaJ domain [IPR001623]", "13": "Small GTP-binding protein domain [IPR005225]", "14": "Pleckstrin homology domain [IPR001849]", "15": "Ubiquitin-like domain [IPR000626]", "16": "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "17": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "18": "Helicase, C-terminal [IPR001650]", "19": "Phox homology [IPR001683]", "20": "K Homology domain, type 1 [IPR004088]", "21": "Double-stranded RNA-binding domain [IPR014720]", "22": "Kinesin motor domain [IPR001752]", "23": "K Homology domain [IPR004087]", "24": "CS domain [IPR007052]", "25": "DEAD/DEAH box helicase domain [IPR011545]", "26": "RNA recognition motif domain [IPR000504]", "27": "RNA helicase, DEAD-box type, Q motif [IPR014014]", "28": "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "29": "Rab-GTPase-TBC domain [IPR000195]", "30": "AP complex, mu/sigma subunit [IPR022775]"}
interpro_domain/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: b545ddf2b7eb3bcbf151a65633f27f590aa8444ad06d8dac2939966d90d8ded7
  • Pointer size: 131 Bytes
  • Size of remote file: 147 kB
interpro_domain/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: cf5998039e28324d547314aa6099517213ed79df9a0e7fe5ea17f5d74be0040a
  • Pointer size: 131 Bytes
  • Size of remote file: 132 kB
interpro_domain/basic/plot_10.png ADDED

Git LFS Details

  • SHA256: 9a6c0ea39bbaf8529935a94a3925236af9b9dcf76990af993fe039b4355a2110
  • Pointer size: 131 Bytes
  • Size of remote file: 136 kB
interpro_domain/basic/plot_11.png ADDED

Git LFS Details

  • SHA256: a01451d8baf71b3674a33a3d69529bd6c8a075f4b698eec37b775d38999656aa
  • Pointer size: 131 Bytes
  • Size of remote file: 145 kB
interpro_domain/basic/plot_12.png ADDED

Git LFS Details

  • SHA256: aca7e300ef95b85542404d915d3532612c9f5dc2ad4ea7053b7a28d92c220add
  • Pointer size: 131 Bytes
  • Size of remote file: 138 kB
interpro_domain/basic/plot_13.png ADDED

Git LFS Details

  • SHA256: d44b49eb935a398507375c96b24851b3a9cf2fced7d1374a68a2417ca31e9423
  • Pointer size: 131 Bytes
  • Size of remote file: 148 kB
interpro_domain/basic/plot_14.png ADDED

Git LFS Details

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  • Pointer size: 131 Bytes
  • Size of remote file: 148 kB
interpro_domain/basic/plot_15.png ADDED

Git LFS Details

  • SHA256: 262439cb37d7a7c1223ff31f7f326b6751337d7e1c876a4ff73bd824c878a362
  • Pointer size: 131 Bytes
  • Size of remote file: 141 kB