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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/consensus.joblib +3 -0
  4. interpro_active_site/df_merge.tsv +1 -0
  5. interpro_active_site/metrics.json +7 -0
  6. interpro_active_site/paths.json +1 -0
  7. interpro_active_site/result.tsv +3 -0
  8. interpro_active_site/selections.json +1 -0
  9. interpro_binding_site/advanced/idx2term.json +1 -0
  10. interpro_binding_site/basic/idx2term.json +1 -0
  11. interpro_binding_site/consensus.joblib +3 -0
  12. interpro_binding_site/df_merge.tsv +1 -0
  13. interpro_binding_site/metrics.json +7 -0
  14. interpro_binding_site/paths.json +1 -0
  15. interpro_binding_site/result.tsv +3 -0
  16. interpro_binding_site/selections.json +1 -0
  17. interpro_conserved_site/advanced/idx2term.json +1 -0
  18. interpro_conserved_site/basic/idx2term.json +1 -0
  19. interpro_conserved_site/consensus.joblib +3 -0
  20. interpro_conserved_site/df_merge.tsv +2 -0
  21. interpro_conserved_site/metrics.json +7 -0
  22. interpro_conserved_site/paths.json +1 -0
  23. interpro_conserved_site/result.tsv +41 -0
  24. interpro_conserved_site/selections.json +1 -0
  25. interpro_domain/advanced/idx2term.json +1 -0
  26. interpro_domain/basic/idx2term.json +1 -0
  27. interpro_domain/basic/plot_0.png +3 -0
  28. interpro_domain/basic/plot_1.png +3 -0
  29. interpro_domain/basic/plot_10.png +3 -0
  30. interpro_domain/basic/plot_2.png +3 -0
  31. interpro_domain/basic/plot_3.png +3 -0
  32. interpro_domain/basic/plot_4.png +3 -0
  33. interpro_domain/basic/plot_5.png +3 -0
  34. interpro_domain/basic/plot_6.png +3 -0
  35. interpro_domain/basic/plot_7.png +3 -0
  36. interpro_domain/basic/plot_8.png +3 -0
  37. interpro_domain/basic/plot_9.png +3 -0
  38. interpro_domain/consensus.joblib +3 -0
  39. interpro_domain/df_merge.tsv +2 -0
  40. interpro_domain/metrics.json +7 -0
  41. interpro_domain/paths.json +1 -0
  42. interpro_domain/result.tsv +253 -0
  43. interpro_domain/selections.json +0 -0
  44. interpro_family/advanced/idx2term.json +1 -0
  45. interpro_family/advanced/plot_0.png +3 -0
  46. interpro_family/advanced/plot_1.png +3 -0
  47. interpro_family/basic/idx2term.json +1 -0
  48. interpro_family/basic/plot_0.png +3 -0
  49. interpro_family/basic/plot_1.png +3 -0
  50. interpro_family/basic/plot_2.png +3 -0
interpro_active_site/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
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+ {}
interpro_active_site/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_active_site/consensus.joblib ADDED
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+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:c0a1bdcad3b6fd42052762acca808c4de9d1d26f2fb18d0dc3a9d1fca7816801
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+ size 85409
interpro_active_site/df_merge.tsv ADDED
@@ -0,0 +1 @@
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3559,
4
+ "annotations_size": 55,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.909090909090909
7
+ }
interpro_active_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C068/C068_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Protein-tyrosine phosphatase, active site [IPR016130] 0.4209212945331697 0.5642477775292268 0.5725855164612743 1.0 0.7157318955765929 9 O60942,Q13614,P10586 3
3
+ Thiolase, acyl-enzyme intermediate active site [IPR020615] 0.4946539110861104 0.4714688009416332 0.6373059942853927 1.0 0.7619962975151435 5 P55084,P09110,P42765,P22307 4
interpro_active_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ACVR1B", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP8", "CDC34", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME3", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCD", "PRKCZ", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN9", "PTPRF", "RIPK1", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UBE2T", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["ACAA1", "ACAA2", "HADHB", "MTMR2", "PTPRF", "RNGTT", "SCP2"]}
interpro_binding_site/advanced/idx2term.json ADDED
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+ {}
interpro_binding_site/basic/idx2term.json ADDED
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+ {}
interpro_binding_site/consensus.joblib ADDED
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+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:38d935a128f7234ee1475199728d69c354178338b2b6677a7dfa278789c7b26f
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+ size 81864
interpro_binding_site/df_merge.tsv ADDED
@@ -0,0 +1 @@
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_binding_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3559,
4
+ "annotations_size": 31,
5
+ "title": "Average number of proteins per term",
6
+ "value": 5.096774193548387
7
+ }
interpro_binding_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C068/C068_val_log2fc"}
interpro_binding_site/result.tsv ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.6997469777902712 0.7378511269969917 0.4606049206580107 0.9999999951121666 0.5491827900153204 2 P34896 1
3
+ Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.6117514759628828 0.4358808738136867 0.6629231626041729 0.9999999999999976 0.7001581818492499 2 O15270 1
interpro_binding_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ACVR1B", "ADSS", "AKT2", "APEX1", "AURKA", "AURKB", "BPNT1", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CEP97", "CETN2", "CHUK", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO9B", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN1", "PKN2", "PLCD3", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCD", "PRKCSH", "PRKCZ", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "USP32", "VRK1", "YES1"], "leading_proteins": ["SHMT1", "SPTLC2"]}
interpro_conserved_site/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_conserved_site/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_conserved_site/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
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+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:e735542c3b897d9535a2912fe1d533d514d882403946824b29750d806cefecdc
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+ size 111457
interpro_conserved_site/df_merge.tsv ADDED
@@ -0,0 +1,2 @@
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Proteasome beta-type subunit, conserved site [IPR016050] 4 8 2.5886847406151494 0.0096343253033266 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 0.0009534063593398 9.54357461344528e-05 1.828578586842436e-06 5.489393781591606e-05
interpro_conserved_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3559,
4
+ "annotations_size": 291,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.7938144329896906
7
+ }
interpro_conserved_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C068/C068_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
@@ -0,0 +1,41 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.8903922369660614 2.5886847406151494 0.0096343253033266 0.9402258138386604 0.0667521110301917 8 P28072,P49721,P28070,P28074 4
3
+ Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.7978151129034758 1.7652205753554937 0.0775267019086451 0.9999999999366777 0.2425835511335027 6 P42356,P78527 2
4
+ Sugar transporter, conserved site [IPR005829] 0.9420860275513046 1.7037301322719804 0.0884315160442639 0.9999999999980108 0.2652945481327917 2 Q5SR56 1
5
+ Thioredoxin, conserved site [IPR017937] 0.6487248490306231 1.6838984407481945 0.0922012977469712 0.9999999999994044 0.2710159358017034 10 O95881,O43396,Q9H1E5 3
6
+ Sterol reductase, conserved site [IPR018083] 0.9853768278965108 1.662489101870848 0.0964147466948017 0.999999999999846 0.2805669128818731 3 O76062,Q14739 2
7
+ Ribosomal protein L3, conserved site [IPR019926] 0.9091931402867574 1.5703865697799293 0.1163252050167975 0.9999999999999998 0.3163610715877391 2 P39023 1
8
+ Guanylate kinase, conserved site [IPR020590] 0.6825048241134318 1.4906599846875164 0.1360507869416989 1.0 0.3534890982145927 7 Q00013,Q92796,Q12959,Q9NZW5 4
9
+ Tetraspanin, conserved site [IPR018503] 0.8827663761596829 1.462988186814009 0.1434706114271535 1.0 0.3621117408592464 2 O60637 1
10
+ Haem oxygenase conserved site [IPR018207] 0.8819229687939205 1.459559138933323 0.1444112761341842 1.0 0.3621117408592464 2 P09601 1
11
+ S100/Calbindin-D9k, conserved site [IPR001751] 0.8560584762440218 1.3544370370269443 0.1755969881459664 1.0 0.4023521539407578 2 P60903 1
12
+ Ribosomal protein L13, conserved site [IPR023563] 0.8313185268484583 1.2541109209553 0.2098016914283382 1.0 0.4303167570199784 2 Q9BYD1 1
13
+ ABC transporter-like, conserved site [IPR017871] 0.5169588913456672 1.1210103584722717 0.262283453238429 1.0 0.493206983082166 12 Q03519,Q03518,P08183 3
14
+ 3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.7956142816980516 1.110265541778487 0.2668846170619028 1.0 0.493206983082166 2 Q16836 1
15
+ Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.8329583802024498 1.1085455974319005 0.2676262582331641 1.0 0.493206983082166 3 P55899,P01889 2
16
+ Ribosomal protein L30, conserved site [IPR018038] 0.7846499859432011 1.0664468999419294 0.2862216702946225 1.0 0.5028174432592226 2 P18124 1
17
+ Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.7191566607633659 0.9818117773114484 0.3261925849618636 1.0 0.5393297853630814 4 Q8N4Q0 1
18
+ Short-chain dehydrogenase/reductase, conserved site [IPR020904] 0.4778148872469793 0.8938801261807006 0.3713860321658644 1.0 0.5816538919293068 11 Q6IAN0,Q06136 2
19
+ Clathrin adaptor complex, small chain [IPR000804] 0.6587712525007564 0.7633909527523843 0.4452302739138436 1.0 0.6422518972869672 4 P61966 1
20
+ Profilin conserved site [IPR027310] 0.6994658420016812 0.7368080972743584 0.4612390583432773 1.0 0.657943950872028 2 P35080 1
21
+ Acyl-CoA dehydrogenase, conserved site [IPR006089] 0.5212675437658557 0.6597023783380355 0.5094448401364771 1.0 0.6960021055385673 6 P26440,Q92947,P49748,P45954 4
22
+ Dynein light chain, type 1/2, conserved site [IPR019763] 0.674725892606117 0.6466590461023405 0.5178526340710299 1.0 0.7023598523140778 2 Q96FJ2 1
23
+ Actin, conserved site [IPR004001] 0.6710711273545045 0.6336398272421102 0.5263159027526063 1.0 0.7023598523140778 2 O96019 1
24
+ Ribosomal protein S9, conserved site [IPR020574] 0.6539218442507633 0.5737104637666712 0.5661637463073941 1.0 0.7231413488214457 2 P82933 1
25
+ RNA polymerase, beta subunit, conserved site [IPR007121] 0.6412707337644028 0.5308371405063816 0.5955316404164006 1.0 0.7374455632390322 2 P30876 1
26
+ AMP-binding, conserved site [IPR020845] 0.404824433849499 0.4975729387226569 0.6187850813782445 1.0 0.7565817591641562 9 O95573,Q4G176,Q9UKU0 3
27
+ Syntaxin/epimorphin, conserved site [IPR006012] 0.4514782256361618 0.4123871202225811 0.6800557019992017 1.0 0.8074162919776844 6 Q9P2W9,O15400 2
28
+ Chromo domain, conserved site [IPR023779] 0.4387003693693742 0.3714649077325317 0.7102912887127539 1.0 0.8146195885170212 6 Q13185,P83916,Q14781,P45973 4
29
+ Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.5853247118358076 0.3578372730833599 0.7204650951401692 1.0 0.8146195885170212 2 P82675 1
30
+ Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745] 0.5844813044700499 0.3554666200128164 0.7222400475511734 1.0 0.8146195885170212 2 Q06481 1
31
+ Proteinase inhibitor I2, Kunitz, conserved site [IPR020901] 0.5844813044700499 0.3554666200128164 0.7222400475511734 1.0 0.8146195885170212 2 Q06481 1
32
+ Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744] 0.5844813044700499 0.3554666200128164 0.7222400475511734 1.0 0.8146195885170212 2 Q06481 1
33
+ Ribosomal RNA adenine methylase transferase, conserved site [IPR020596] 0.5451222940680228 0.2539579091839653 0.7995280758322156 1.0 0.8914278546635047 2 Q9UNQ2 1
34
+ DNA topoisomerase, type IIA, conserved site [IPR018522] 0.5007028394714539 0.1627697259290974 0.8706997455493406 1.0 0.9555280519929732 2 Q02880 1
35
+ DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.4709024458813525 0.1162038823819052 0.9074909599044358 1.0 0.9817095514207838 2 P09884 1
36
+ Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728] 0.4534720269890306 0.094275869478396 0.924890017893713 1.0 0.9894963059083473 2 Q07820 1
37
+ Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717] 0.4534720269890306 0.094275869478396 0.924890017893713 1.0 0.9894963059083473 2 Q07820 1
38
+ Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726] 0.4534720269890306 0.094275869478396 0.924890017893713 1.0 0.9894963059083473 2 Q07820 1
39
+ D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.360056258790439 0.0524400380636166 0.9581780722269828 1.0 1.0 4 Q13363,P56545,O43175 3
40
+ Cullin, conserved site [IPR016157] 0.2526388850625677 0.0218230296305782 0.9825891235714974 1.0 1.0 6 Q13619 1
41
+ Acyl-CoA-binding protein, ACBP, conserved site [IPR022408] 0.3276152980877428 0.0199883723134781 0.9840526482635032 1.0 1.0 3 Q9H3P7,Q5T8D3 2
interpro_conserved_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Folylpolyglutamate synthetase, conserved site [IPR018109]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARHGEF7", "ARIH2", "ARSA", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BCAT2", "BCR", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRPF3", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DIS3L2", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTX3L", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA2", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FPGS", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GMPPB", "GMPR2", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "ISCA2", "ITGA6", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LIG4", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MFSD14B", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP1", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RIOK2", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCAP", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SGSH", "SHPRH", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC4A2", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STMN1", "STOM", "STRN", "STRN3", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM56", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP32", "USP33", "USP34", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ACADSB", "ACADVL", "ACBD3", "ACBD5", "ACSF3", "ACSL3", "ACSL6", "ACTL6A", "AP1S1", "APLP2", "CBX1", "CBX2", "CBX3", "CBX5", "CTBP1", "CTBP2", "CUL4A", "DHRS7B", "DIMT1", "DLG1", "DLG3", "DYNLL2", "FCGRT", "GCDH", "HADH", "HLA-B", "HMOX1", "IVD", "KDSR", "LBR", "MCL1", "MFSD14B", "MPP1", "MPP6", "MRPL13", "MRPS5", "MRPS9", "PFN2", "PHGDH", "PI4KA", "POLA1", "POLR2B", "PRKDC", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "RPL3", "RPL7", "S100A10", "STX18", "STX7", "TAP1", "TAP2", "TM7SF2", "TMX4", "TOP2B", "TSPAN3", "TXNDC12", "TXNL1", "ZADH2"]}
interpro_domain/advanced/idx2term.json ADDED
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+ {"0": "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "1": "Guanylate kinase-like domain [IPR008144]", "2": "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "3": "Thioredoxin domain [IPR013766]", "4": "Immunoglobulin-like domain [IPR007110]", "5": "PDZ domain [IPR001478]", "6": "Small GTP-binding protein domain [IPR005225]", "7": "Forkhead-associated (FHA) domain [IPR000253]", "8": "AAA+ ATPase domain [IPR003593]", "9": "Chaperone DnaJ, C-terminal [IPR002939]", "10": "DNA2/NAM7 helicase-like, C-terminal [IPR041679]"}
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+ version https://git-lfs.github.com/spec/v1
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+ size 404833
interpro_domain/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 3 8 2.136139286262829 0.0326680623955364 2.878640776699029 6.735436893203883 -0.1009242226376213 0.5398631989476717 1.7790119700005456 1.6967720791950751 0.9747821830158722 0.3245983921794569 1.0 0.0727733471903131 0.1419203898220533 0.3247468214281712 0.00630824692371
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3559,
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+ "annotations_size": 2840,
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+ "title": "Average number of proteins per term",
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+ "value": 2.242957746478873
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+ }
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+ {"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C068/C068_val_log2fc"}
interpro_domain/result.tsv ADDED
@@ -0,0 +1,253 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.7823159633115745 2.136139286262829 0.0326680623955364 1.0 0.1362668687647821 8 Q9Y4A5,P42356,P78527 3
3
+ Major facilitator superfamily domain [IPR020846] 0.8563963585310543 1.8607839572412048 0.0627746919120229 1.0 0.2053918491130703 5 Q14728,P53985,Q5SR56 3
4
+ Phospholipid/glycerol acyltransferase [IPR002123] 0.7953413985086556 1.7554342871406097 0.0791850515798917 1.0 0.2392399430711623 6 Q92604 1
5
+ Ricin B, lectin domain [IPR000772] 0.8188737495593124 1.7155563796815378 0.08624326800967 1.0 0.2512111601512442 5 Q10472,Q8N4A0 2
6
+ Tudor domain [IPR002999] 0.65457844184835 1.7114314825110264 0.0870014895890962 1.0 0.2528282241538403 10 Q14739 1
7
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.7790166619862826 1.6906522145903158 0.0909032458779885 1.0 0.2594625309482287 6 Q9UIQ6,P09960,Q9NZ08 3
8
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 0.7790166619862826 1.6906522145903158 0.0909032458779885 1.0 0.2594625309482287 6 Q9UIQ6,P09960,Q9NZ08 3
9
+ Polyketide synthase, enoylreductase domain [IPR020843] 0.7206352274150895 1.652999910860671 0.098330881709916 1.0 0.2691558337655307 7 Q8N4Q0,Q14914 2
10
+ RBM3/CIRBP, RNA recognition motif [IPR034278] 0.9218442507731228 1.6217328107816371 0.1048605702476226 1.0 0.28039254205176 2 Q14011 1
11
+ Brix domain [IPR007109] 0.7927023796781151 1.61330127918665 0.1066790687813652 1.0 0.2826199210252587 5 Q9H7B2,Q8TDN6,Q9NQ55 3
12
+ Glycosyltransferase 2-like [IPR001173] 0.792212179199794 1.6113792389919588 0.1070970894343275 1.0 0.2834629394161138 5 Q10472,Q8N4A0 2
13
+ ERAP1-like C-terminal domain [IPR024571] 0.8770853571302927 1.571865701856349 0.115981700289478 1.0 0.2972816144603951 4 Q9UIQ6,Q9NZ08 2
14
+ Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854] 0.905257239246553 1.5544006040951983 0.120088889238676 1.0 0.3028884950602485 2 Q96RL7 1
15
+ Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543] 0.905257239246553 1.5544006040951983 0.120088889238676 1.0 0.3028884950602485 2 Q96RL7 1
16
+ Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646] 0.905257239246553 1.5544006040951983 0.120088889238676 1.0 0.3028884950602485 2 Q96RL7 1
17
+ VPS13, repeated coiled region [IPR031642] 0.905257239246553 1.5544006040951983 0.120088889238676 1.0 0.3028884950602485 2 Q96RL7 1
18
+ Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645] 0.905257239246553 1.5544006040951983 0.120088889238676 1.0 0.3028884950602485 2 Q96RL7 1
19
+ Autophagy-related, C-terminal [IPR015412] 0.905257239246553 1.5544006040951983 0.120088889238676 1.0 0.3028884950602485 2 Q96RL7 1
20
+ TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8705094272918377 1.5473270526477076 0.1217844015605287 1.0 0.3055735096275888 4 Q96G23 1
21
+ ABC transporter type 1, transmembrane domain [IPR011527] 0.6474035684414602 1.538611174059675 0.1238992489690273 1.0 0.3085486095996235 8 Q03519,Q03518,P08183 3
22
+ Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.6296573306481267 1.5244201467598035 0.1274037905195713 1.0 0.3122742989868429 9 Q9NZW5,Q00013,Q9UDY2,Q12959,Q92796 5
23
+ Guanylate kinase-like domain [IPR008144] 0.6296573306481267 1.5244201467598035 0.1274037905195713 1.0 0.3122742989868429 9 Q9NZW5,Q00013,Q9UDY2,Q12959,Q92796 5
24
+ Complex 1 LYR protein domain [IPR008011] 0.8951363508574598 1.5132751938759157 0.1302097710061742 1.0 0.3166059500492593 2 Q9Y6M9 1
25
+ N-acetylgalactosaminyltransferase [IPR045885] 0.8558176394505062 1.4924168025303943 0.1355899128790163 1.0 0.3251803523422534 4 Q10472,Q8N4A0 2
26
+ Peptidase M3A/M3B catalytic domain [IPR001567] 0.9299775028121384 1.4611628288486762 0.1439707613014844 1.0 0.338754732474081 3 P52888,Q9BYT8 2
27
+ Sterol-sensing domain [IPR000731] 0.9282902137232826 1.4550158024301951 0.1456648867526866 1.0 0.3399246330136647 3 Q12770,O15118 2
28
+ HECT domain [IPR000569] 0.5916629484110882 1.4532033188528708 0.146167310970694 1.0 0.3408170469267414 11 Q96PU5,P46934 2
29
+ Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.6716048483407517 1.4439610689984117 0.1487499266566589 1.0 0.3454209253515221 7 P13674,Q32P28 2
30
+ Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.6716048483407517 1.4439610689984117 0.1487499266566589 1.0 0.3454209253515221 7 P13674,Q32P28 2
31
+ MENTAL domain [IPR019498] 0.8754568456564492 1.4332700922619843 0.151780665513175 1.0 0.3513198422522282 2 Q14849 1
32
+ MHC class I-like antigen recognition-like [IPR011161] 0.7450958653923986 1.425683779950413 0.1539596405636067 1.0 0.3540448414580107 5 P55899,P01889 2
33
+ PIK-related kinase [IPR014009] 0.8331665957223632 1.4075761995442255 0.1592565991060952 1.0 0.360389435427339 4 Q9Y4A5,P78527 2
34
+ FATC domain [IPR003152] 0.8331665957223632 1.4075761995442255 0.1592565991060952 1.0 0.360389435427339 4 Q9Y4A5,P78527 2
35
+ Homeobox domain [IPR001356] 0.9059638748711824 1.3736527644998582 0.1695495077308577 1.0 0.374141881861411 3 Q96G23 1
36
+ COP9 signalosome complex subunit 7, helix I [IPR041481] 0.8605566488613992 1.372709184338354 0.1698427728399183 1.0 0.3744980394917453 2 Q9H9Q2 1
37
+ Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.9047117754416976 1.369089621407481 0.1709712621247863 1.0 0.3764018483987543 3 Q32P28 1
38
+ 4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.8210785174318456 1.3622414068468385 0.1731217122046331 1.0 0.3784955062826467 4 Q16134 1
39
+ Fatty acid desaturase domain [IPR005804] 0.8571830193983624 1.359004447786502 0.1741451792947024 1.0 0.3792732432491985 2 O15121 1
40
+ S100/CaBP-9k-type, calcium binding, subdomain [IPR013787] 0.8560584762440218 1.3544370370269443 0.1755969881459664 1.0 0.3803421615463071 2 P60903 1
41
+ Sec63 domain [IPR004179] 0.9002639135629367 1.3528809487043942 0.1760936666097361 1.0 0.3803421615463071 3 Q9UGP8 1
42
+ LSM domain, eukaryotic/archaea-type [IPR001163] 0.6049169475239 1.344622210848968 0.1787472669507073 1.0 0.38334368460713 8 Q9Y333,P62316,P62310,P62304 4
43
+ Alcohol dehydrogenase-like, C-terminal [IPR013149] 0.6450794573499384 1.3299237922008866 0.1835433814753242 1.0 0.3884226552831005 7 Q14914 1
44
+ MABP domain [IPR023341] 0.8442507731234101 1.306511079585141 0.1913788137006677 1.0 0.4002325706258443 2 Q96EY5 1
45
+ KOW [IPR005824] 0.679418662929633 1.2894928647984183 0.1972267953216087 1.0 0.4047253745029007 6 Q96A35 1
46
+ LRRC8, pannexin-like TM region [IPR021040] 0.839752600506036 1.288272433202335 0.1976511456199166 1.0 0.4047253745029007 2 Q8IWT6 1
47
+ Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120] 0.8391903289288669 1.285993472487602 0.1984453397768328 1.0 0.4057485708899966 2 Q8WVX9 1
48
+ Fatty acyl-CoA reductase, C-terminal [IPR033640] 0.8391903289288669 1.285993472487602 0.1984453397768328 1.0 0.4057485708899966 2 Q8WVX9 1
49
+ Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.8335676131571442 1.263215618355713 0.2065117014118689 1.0 0.414578597683627 2 Q13505 1
50
+ Metaxin, glutathione S-transferase domain [IPR033468] 0.8335676131571442 1.263215618355713 0.2065117014118689 1.0 0.414578597683627 2 Q13505 1
51
+ PIK-related kinase, FAT [IPR003151] 0.8643491909671678 1.2221819033337598 0.2216388457548128 1.0 0.4356085272966564 3 P78527 1
52
+ Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.5591610632221907 1.194045551850779 0.2324601499548091 1.0 0.4509472854314603 9 P45954,Q15067,P49748,Q92947,Q709F0 5
53
+ GRAM domain [IPR004182] 0.8526147133256745 1.179610208554631 0.2381552808508069 1.0 0.4576190782248253 3 Q66K14 1
54
+ Phospholipase D/Transphosphatidylase [IPR001736] 0.8116390216474444 1.1746406314822253 0.2401385204271462 1.0 0.4578349509192657 2 Q8IV08 1
55
+ Major sperm protein (MSP) domain [IPR000535] 0.848142315542781 1.1634107920054746 0.244662873008177 1.0 0.4628259355792135 3 Q8NHP6 1
56
+ Immunoglobulin C1-set [IPR003597] 0.7677353193151668 1.162296404998966 0.2451150864037741 1.0 0.4628502961347862 4 P55899,P01889 2
57
+ P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.5609420697671662 1.1427050464389417 0.253161073860721 1.0 0.4714606227963592 8 Q9HD20,P16615,P05023,P35670 4
58
+ Disks large homologue 1, N-terminal PEST domain [IPR019590] 0.8034860837784579 1.1418439768211517 0.2535188789822336 1.0 0.4715085895936761 2 Q12959 1
59
+ PDZ-associated domain of NMDA receptors [IPR019583] 0.8034860837784579 1.1418439768211517 0.2535188789822336 1.0 0.4715085895936761 2 Q12959 1
60
+ ABC transporter-like, ATP-binding domain [IPR003439] 0.5169588913456672 1.1210103584722717 0.262283453238429 1.0 0.4802611264971879 12 Q03519,Q03518,P08183 3
61
+ 3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.7956142816980516 1.110265541778487 0.2668846170619028 1.0 0.4858668669588487 2 Q16836 1
62
+ 3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.7956142816980516 1.110265541778487 0.2668846170619028 1.0 0.4858668669588487 2 Q16836 1
63
+ CELF1/2, RNA recognition motif 3 [IPR034199] 0.7860556648861293 1.0720529030528627 0.2836962710504291 1.0 0.5010556030990166 2 O95319 1
64
+ CELF1/2, RNA recognition motif 2 [IPR034198] 0.7860556648861293 1.0720529030528627 0.2836962710504291 1.0 0.5010556030990166 2 O95319 1
65
+ CELF1/2, RNA recognition motif 1 [IPR034196] 0.7860556648861293 1.0720529030528627 0.2836962710504291 1.0 0.5010556030990166 2 O95319 1
66
+ Ribosomal protein L7, eukaryotic/archaeal [IPR035808] 0.7846499859432011 1.0664468999419294 0.2862216702946225 1.0 0.5021621633350708 2 P18124 1
67
+ Ribosomal protein L30, N-terminal [IPR012988] 0.7846499859432011 1.0664468999419294 0.2862216702946225 1.0 0.5021621633350708 2 P18124 1
68
+ Ribosomal protein L30, ferredoxin-like fold domain [IPR016082] 0.7846499859432011 1.0664468999419294 0.2862216702946225 1.0 0.5021621633350708 2 P18124 1
69
+ MoaB/Mog domain [IPR001453] 0.7832443070002784 1.0608445747164263 0.2887605411123872 1.0 0.5040442143572095 2 Q8NFF5 1
70
+ EB1, C-terminal [IPR004953] 0.7790272701714849 1.0440604231977637 0.2964574350196007 1.0 0.5078040503351424 2 Q15691 1
71
+ L27 domain [IPR004172] 0.6423066319520677 1.0184924849840828 0.308443970397616 1.0 0.5195616108714292 5 Q12959,Q9NZW5 2
72
+ Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.7708743323024971 1.0117146200532845 0.3116745231063125 1.0 0.5219007643870323 2 P51116 1
73
+ GMP phosphodiesterase, delta subunit [IPR008015] 0.7971674451686634 0.9803321194476288 0.3269222048715801 1.0 0.5388619047215829 3 Q13432 1
74
+ Ribosomal protein S4/S9, N-terminal [IPR001912] 0.7545684565645121 0.9474886751323974 0.3433898243104427 1.0 0.55316341522499 2 Q9NV31 1
75
+ AMP-binding enzyme, C-terminal domain [IPR025110] 0.5923285011516156 0.937105282577516 0.348704404409939 1.0 0.5579270470559023 6 Q4G176,Q9UKU0 2
76
+ Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075] 0.553175685077541 0.9348856949447688 0.349847209987582 1.0 0.5590978183906303 7 Q92947,P49748,Q709F0,P45954 4
77
+ Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786] 0.553175685077541 0.9348856949447688 0.349847209987582 1.0 0.5590978183906303 7 Q92947,P49748,Q709F0,P45954 4
78
+ JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.5083111011696133 0.9026333349735706 0.3667205284502433 1.0 0.5719309724320104 8 O15372,O00303,Q6P2Q9 3
79
+ SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.6969816015847234 0.9005757059864036 0.3678139563257478 1.0 0.5726927828756162 4 Q08J23 1
80
+ Ribosomal protein L18e/L15P [IPR021131] 0.774184476940366 0.8991656233443136 0.3685644480455456 1.0 0.5735468670955342 3 Q07020,Q9P015 2
81
+ Fxr1, tudor domain [IPR041560] 0.7710911136107893 0.8883299593628623 0.3743632887554797 1.0 0.5750090535779138 3 P51116,Q06787 2
82
+ Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.7710911136107893 0.8883299593628623 0.3743632887554797 1.0 0.5750090535779138 3 P51116,Q06787 2
83
+ Agenet-like domain [IPR008395] 0.7710911136107893 0.8883299593628623 0.3743632887554797 1.0 0.5750090535779138 3 P51116,Q06787 2
84
+ Fragile X-related 1 protein, C-terminal core [IPR022034] 0.7710911136107893 0.8883299593628623 0.3743632887554797 1.0 0.5750090535779138 3 P51116,Q06787 2
85
+ Thioredoxin domain [IPR013766] 0.4006339075249028 0.8467559201179321 0.3971311824145911 1.0 0.5966665596118313 24 Q9H1E5,Q13162,Q9Y320,Q9P2K2,O43396,O95881,Q9H3N1 7
86
+ Class I myosin, motor domain [IPR036072] 0.7587176602924486 0.8452298110987206 0.3979825409119777 1.0 0.5966665596118313 3 O00159,O94832 2
87
+ Class I myosin tail homology domain [IPR010926] 0.7587176602924486 0.8452298110987206 0.3979825409119777 1.0 0.5966665596118313 3 O00159,O94832 2
88
+ Amino acid permease/ SLC12A domain [IPR004841] 0.7556894343739611 0.8347447149994981 0.403861459476269 1.0 0.5985158870435516 3 Q9Y666 1
89
+ SLC12A transporter, C-terminal [IPR018491] 0.7556894343739611 0.8347447149994981 0.403861459476269 1.0 0.5985158870435516 3 Q9Y666 1
90
+ Peptidase S8/S53 domain [IPR000209] 0.7250491987629912 0.8331918270395793 0.4047365512406906 1.0 0.5985158870435516 2 O14773 1
91
+ Longin domain [IPR010908] 0.7542182227221623 0.8296601853076305 0.4067309382263055 1.0 0.5991264857690394 3 O75396,O15498 2
92
+ v-SNARE, coiled-coil homology domain [IPR042855] 0.7542182227221623 0.8296601853076305 0.4067309382263055 1.0 0.5991264857690394 3 O75396,O15498 2
93
+ Protein-tyrosine phosphatase, catalytic [IPR003595] 0.4913552716779579 0.826527354593036 0.4085050073542995 1.0 0.6011161766249796 8 Q12923,Q13614,P10586 3
94
+ MHC class I, alpha chain, C-terminal [IPR010579] 0.749861649282684 0.8146412304892904 0.4152777025203729 1.0 0.6064641787141768 3 P01889 1
95
+ MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.749861649282684 0.8146412304892904 0.4152777025203729 1.0 0.6064641787141768 3 P01889 1
96
+ AP complex, mu/sigma subunit [IPR022775] 0.5225476479417551 0.8058516973890798 0.4203283652516578 1.0 0.6109173783596256 7 P61966 1
97
+ TRASH domain [IPR011017] 0.7464957931256421 0.8030771939227681 0.4219301185041986 1.0 0.6124296228249291 3 Q9UBW7 1
98
+ Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939] 0.7168962608940121 0.8021712052434433 0.4224539304003416 1.0 0.6124296228249291 2 Q96C36 1
99
+ Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036] 0.7168962608940121 0.8021712052434433 0.4224539304003416 1.0 0.6124296228249291 2 Q96C36 1
100
+ Ribosomal protein/NADH dehydrogenase domain [IPR007741] 0.7435320584926748 0.7929242308225986 0.4278219689332636 1.0 0.6158207763661777 3 Q8N983,P82663 2
101
+ Fzo/mitofusin HR2 domain [IPR006884] 0.713522631430975 0.789414701804465 0.4298696659164163 1.0 0.6160719745151179 2 O95140 1
102
+ RBM1CTR [IPR012604] 0.7118358166994521 0.7830547028523702 0.4335949894876683 1.0 0.6194214135538119 2 P38159 1
103
+ Hemimethylated DNA-binding domain [IPR011722] 0.7098678661793618 0.7756504386657181 0.4379554104837311 1.0 0.6237679868474405 2 O94952 1
104
+ Zinc finger, CHHC-type [IPR012996] 0.7353768278964924 0.7651359701464419 0.4441905826588512 1.0 0.6314932977741998 3 P31943,P55795 2
105
+ MPN domain [IPR037518] 0.4611321385619495 0.7396919348770447 0.4594869429489914 1.0 0.6428838634631998 9 O15372,O00303,Q6P2Q9 3
106
+ Serine hydroxymethyltransferase-like domain [IPR039429] 0.6997469777902712 0.7378511269969917 0.4606049206580107 1.0 0.6439150866792264 2 P34896 1
107
+ Death domain [IPR000488] 0.7201912260967409 0.7140259084740873 0.4752111589170273 1.0 0.6551084969094246 3 Q96FV9,Q13546 2
108
+ TATA box binding protein associated factor (TAF) [IPR004823] 0.6879392746696558 0.6943898426149355 0.4874377619352734 1.0 0.662916818037548 2 P62805 1
109
+ SUN coiled coil domain 2 [IPR040994] 0.679224065223488 0.662794144207911 0.5074624045195522 1.0 0.6719169230376165 2 Q9UH99 1
110
+ Chromo domain subgroup [IPR017984] 0.6957255343082155 0.6336785917433092 0.5262905990290583 1.0 0.6781372465692409 3 Q13185,P45973 2
111
+ Chromo shadow domain [IPR008251] 0.6957255343082155 0.6336785917433092 0.5262905990290583 1.0 0.6781372465692409 3 Q13185,P45973 2
112
+ Tyrosine-specific protein phosphatases domain [IPR000387] 0.4257859227333569 0.6275261171559344 0.5303144218668752 1.0 0.6787259838224089 10 O60942,Q12923,Q13614,P10586 4
113
+ Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.6128719324826588 0.6055727672085978 0.5447984906012873 1.0 0.6876567614700693 4 Q86TI2 1
114
+ Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.6584200168681433 0.5892364748525881 0.5557026521870774 1.0 0.6949341841529281 2 O43390 1
115
+ Calcineurin-like phosphoesterase domain, ApaH type [IPR004843] 0.4332455861088182 0.5756150378025131 0.5648754143982759 1.0 0.6985146145657191 8 O00743,P49959 2
116
+ Exportin-1/Importin-beta-like [IPR013598] 0.5964024105214125 0.5514819868789538 0.5813033115106652 1.0 0.7094548365665188 4 Q9Y5L0,O43592 2
117
+ RNA polymerase Rpb2, domain 2 [IPR007642] 0.6412707337644028 0.5308371405063816 0.5955316404164006 1.0 0.7139340898195768 2 P30876 1
118
+ RNA polymerase Rpb2, domain 7 [IPR007641] 0.6412707337644028 0.5308371405063816 0.5955316404164006 1.0 0.7139340898195768 2 P30876 1
119
+ DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120] 0.6412707337644028 0.5308371405063816 0.5955316404164006 1.0 0.7139340898195768 2 P30876 1
120
+ RNA polymerase, beta subunit, protrusion [IPR007644] 0.6412707337644028 0.5308371405063816 0.5955316404164006 1.0 0.7139340898195768 2 P30876 1
121
+ RNA polymerase Rpb2, domain 3 [IPR007645] 0.6412707337644028 0.5308371405063816 0.5955316404164006 1.0 0.7139340898195768 2 P30876 1
122
+ Immunoglobulin-like domain [IPR007110] 0.363986034321639 0.5123147961992657 0.6084307114979111 1.0 0.7269428778519424 17 P01889,P55899,P04439,P10586,Q9Y639 5
123
+ Bromo adjacent homology (BAH) domain [IPR001025] 0.5839662447257487 0.5117271582776516 0.6088419761274664 1.0 0.7270325128123369 4 Q13330,P26358,Q86U86 3
124
+ RNA-binding S4 domain [IPR002942] 0.6543869516310318 0.5048850158721173 0.6136395990051224 1.0 0.7307884167076834 3 P46781,Q9NV31 2
125
+ Legume-like lectin [IPR005052] 0.6333989316839939 0.5047878105831919 0.6137078781154313 1.0 0.7307884167076834 2 Q12907 1
126
+ DFDF domain [IPR025762] 0.6274950801236923 0.4855863029384329 0.6272605096888919 1.0 0.7438078695267026 2 Q9BX40 1
127
+ Lsm14-like, N-terminal [IPR025609] 0.6274950801236923 0.4855863029384329 0.6272605096888919 1.0 0.7438078695267026 2 Q9BX40 1
128
+ FDF domain [IPR019050] 0.6274950801236923 0.4855863029384329 0.6272605096888919 1.0 0.7438078695267026 2 Q9BX40 1
129
+ 3'-5' exonuclease domain [IPR002562] 0.6457018045195904 0.4791541970612308 0.6318289359761742 1.0 0.7473650595738266 3 Q9NVH0 1
130
+ PDZ domain [IPR001478] 0.3373227992620867 0.4786139611621588 0.632213284421818 1.0 0.7473650595738266 27 Q12923,O00151,Q9NZW5,Q6ZWJ1,Q00013,Q9HD26,Q9UDY2,O14908,Q8TEW0,Q12959,Q92796 11
131
+ Alcohol dehydrogenase, N-terminal [IPR013154] 0.4661114355821938 0.4611657214789049 0.6446797127496269 1.0 0.7600209149891823 6 Q8N4Q0 1
132
+ Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.4890104094022419 0.4529272371616525 0.6506011372965403 1.0 0.7647068494180692 5 Q12923,P10586 2
133
+ von Willebrand factor, type A [IPR002035] 0.4319107017523407 0.4500113449971109 0.6527022602420265 1.0 0.7659811649121303 7 Q86YQ8 1
134
+ Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.6343331692941918 0.4462682328044474 0.6554035002993945 1.0 0.76842550193192 3 Q00839 1
135
+ L27 domain, C-terminal [IPR014775] 0.5540591750298709 0.4205652830235424 0.6740725491601602 1.0 0.7852198685868971 4 Q9NZW5 1
136
+ Myosin head, motor domain [IPR001609] 0.3825034985695236 0.4096217899997465 0.6820834100352746 1.0 0.7929254541548014 9 O00159,Q9Y4I1,O94832 3
137
+ C2 domain [IPR000008] 0.3381905313404856 0.404534679374294 0.685819581503373 1.0 0.7959655134734692 19 Q86YQ8,Q96PU5 2
138
+ Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.612706083555439 0.3864079842496782 0.6991945378801883 1.0 0.8068722013733176 3 Q9NR33 1
139
+ IBR domain [IPR002867] 0.6107113823390624 0.3810769486312779 0.7031461515381183 1.0 0.8088031876744658 3 Q9UBS8 1
140
+ TRIAD supradomain [IPR044066] 0.6107113823390624 0.3810769486312779 0.7031461515381183 1.0 0.8088031876744658 3 Q9UBS8 1
141
+ Ribosomal protein S5, C-terminal [IPR005324] 0.5853247118358076 0.3578372730833599 0.7204650951401692 1.0 0.8240244889174889 2 P82675 1
142
+ Ribosomal protein S5, N-terminal [IPR013810] 0.5853247118358076 0.3578372730833599 0.7204650951401692 1.0 0.8240244889174889 2 P82675 1
143
+ Amyloidogenic glycoprotein, copper-binding [IPR011178] 0.5844813044700499 0.3554666200128164 0.7222400475511734 1.0 0.8240244889174889 2 Q06481 1
144
+ Amyloidogenic glycoprotein, E2 domain [IPR024329] 0.5844813044700499 0.3554666200128164 0.7222400475511734 1.0 0.8240244889174889 2 Q06481 1
145
+ Beta-amyloid precursor protein C-terminal [IPR019543] 0.5844813044700499 0.3554666200128164 0.7222400475511734 1.0 0.8240244889174889 2 Q06481 1
146
+ Amyloidogenic glycoprotein, heparin-binding [IPR015849] 0.5844813044700499 0.3554666200128164 0.7222400475511734 1.0 0.8240244889174889 2 Q06481 1
147
+ Amyloidogenic glycoprotein, extracellular [IPR008154] 0.5844813044700499 0.3554666200128164 0.7222400475511734 1.0 0.8240244889174889 2 Q06481 1
148
+ Pancreatic trypsin inhibitor Kunitz domain [IPR002223] 0.5844813044700499 0.3554666200128164 0.7222400475511734 1.0 0.8240244889174889 2 Q06481 1
149
+ CRAL-TRIO lipid binding domain [IPR001251] 0.4333049995894952 0.35469265474377 0.7228198542972812 1.0 0.8240244889174889 6 P21359,Q8NHP6,P43378 3
150
+ CCAAT-binding factor [IPR005612] 0.6006171280947599 0.3546196891616862 0.7228745237990084 1.0 0.8240244889174889 3 Q8WTT2 1
151
+ Metastasis-associated protein MTA1, R1 domain [IPR035170] 0.583637897104292 0.3531037411146616 0.7240106683112986 1.0 0.8241243679375102 2 Q13330 1
152
+ HRDC domain [IPR002121] 0.5971122643233711 0.3456417627792536 0.7296119560355685 1.0 0.8281766407438107 3 Q14191 1
153
+ Small GTP-binding protein domain [IPR005225] 0.2828706091524789 0.3404869925149226 0.7334898167440236 1.0 0.8315812692826455 48 P18085,Q9BW83,P63000,Q6IQ22,P51149,P13639,P36404,Q15286,P20338,P60953,P61106,P61020,Q9BZG1,P20337 14
154
+ Replication factor C, C-terminal [IPR013748] 0.5902026752263414 0.3282668569186314 0.7427099012860952 1.0 0.837687100735707 3 P40937 1
155
+ Pumilio homology domain [IPR033133] 0.5670508855777239 0.3082566856084082 0.7578870221258731 1.0 0.8505697476387524 2 Q14671 1
156
+ Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038] 0.437983155620298 0.298960155500128 0.7649704472521517 1.0 0.8564672812148615 5 P62424 1
157
+ Core histone macro-H2A, macro domain [IPR035796] 0.5633961203261071 0.2988026008615294 0.7650906663528534 1.0 0.8564672812148615 2 O75367 1
158
+ RNA polymerase Rpb1, domain 1 [IPR007080] 0.5704594204454583 0.2810929565207964 0.7786391033521252 1.0 0.8665106009091048 3 O14802 1
159
+ RNA polymerase Rpb1, domain 3 [IPR007066] 0.5704594204454583 0.2810929565207964 0.7786391033521252 1.0 0.8665106009091048 3 O14802 1
160
+ RNA polymerase, alpha subunit [IPR000722] 0.5704594204454583 0.2810929565207964 0.7786391033521252 1.0 0.8665106009091048 3 O14802 1
161
+ RNA polymerase Rpb1, domain 5 [IPR007081] 0.5704594204454583 0.2810929565207964 0.7786391033521252 1.0 0.8665106009091048 3 O14802 1
162
+ RNA polymerase Rpb1, domain 4 [IPR007083] 0.5704594204454583 0.2810929565207964 0.7786391033521252 1.0 0.8665106009091048 3 O14802 1
163
+ RNA polymerase, N-terminal [IPR006592] 0.5704594204454583 0.2810929565207964 0.7786391033521252 1.0 0.8665106009091048 3 O14802 1
164
+ Serine-threonine protein phosphatase, N-terminal [IPR031675] 0.5490581951082257 0.2632685988726224 0.79234356066867 1.0 0.8779772580175664 2 P62140 1
165
+ Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598] 0.5451222940680228 0.2539579091839653 0.7995280758322156 1.0 0.8838691067977783 2 Q9UNQ2 1
166
+ Kinesin-associated [IPR032405] 0.5545217662001567 0.2458248532345285 0.8058178171921992 1.0 0.8891863109222586 3 Q12756 1
167
+ Gamma tubulin complex component protein, N-terminal [IPR041470] 0.5496957019245512 0.2356620133013639 0.8136949487102787 1.0 0.8939627289505577 3 Q9UGJ1 1
168
+ Gamma tubulin complex component, C-terminal [IPR040457] 0.5496957019245512 0.2356620133013639 0.8136949487102787 1.0 0.8939627289505577 3 Q9UGJ1 1
169
+ Peptidase M16, C-terminal [IPR007863] 0.3582254380432565 0.2181923971456632 0.827279208582463 1.0 0.9031255349374392 7 Q5JRX3,Q10713,P31930 3
170
+ Peptidase M16, N-terminal [IPR011765] 0.3582254380432565 0.2181923971456632 0.827279208582463 1.0 0.9031255349374392 7 Q5JRX3,Q10713,P31930 3
171
+ ENTH domain [IPR013809] 0.5374015748031522 0.2108879688009311 0.832974692515231 1.0 0.9070091210112832 3 Q14677,Q13492 2
172
+ Proteasome component (PCI) domain [IPR000717] 0.2911485141412844 0.2000676897230028 0.8414276423369014 1.0 0.9120818718461068 20 Q9H9Q2,Q9UBW8,Q5JVF3,Q9UNS2 4
173
+ Forkhead-associated (FHA) domain [IPR000253] 0.3099981451012181 0.1934933031712077 0.8465726502529038 1.0 0.9166093506360072 12 O96017,Q12756,P85037,Q15058,P46013 5
174
+ AAA+ ATPase domain [IPR003593] 0.2639031400839108 0.1849067972904866 0.8533021394618152 1.0 0.9210863078949278 58 Q8N3C0,Q9NU22,Q03518,Q9HCN4,Q03519,P28288,Q9Y276,P08183 8
175
+ Pleckstrin homology domain [IPR001849] 0.2762401684127812 0.1711144161086097 0.8641338006369639 1.0 0.9299507365702832 32 Q9NZM3,Q9BXW6,Q12756,Q15057 4
176
+ DTHCT [IPR012542] 0.5007028394714539 0.1627697259290974 0.8706997455493406 1.0 0.9328144348658788 2 Q02880 1
177
+ DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506] 0.5007028394714539 0.1627697259290974 0.8706997455493406 1.0 0.9328144348658788 2 Q02880 1
178
+ DNA topoisomerase 2, TOPRIM domain [IPR034157] 0.5007028394714539 0.1627697259290974 0.8706997455493406 1.0 0.9328144348658788 2 Q02880 1
179
+ DNA topoisomerase, type IIA, domain A [IPR002205] 0.5007028394714539 0.1627697259290974 0.8706997455493406 1.0 0.9328144348658788 2 Q02880 1
180
+ C-terminal associated domain of TOPRIM [IPR031660] 0.5007028394714539 0.1627697259290974 0.8706997455493406 1.0 0.9328144348658788 2 Q02880 1
181
+ TOPRIM domain [IPR006171] 0.5007028394714539 0.1627697259290974 0.8706997455493406 1.0 0.9328144348658788 2 Q02880 1
182
+ CNNM, transmembrane domain [IPR002550] 0.4852403710992249 0.1371503225883609 0.8909119765756468 1.0 0.9451587648393116 2 Q6P4Q7 1
183
+ Ion transporter-like, CBS domain [IPR044751] 0.4852403710992249 0.1371503225883609 0.8909119765756468 1.0 0.9451587648393116 2 Q6P4Q7 1
184
+ Helicase/SANT-associated domain [IPR014012] 0.491282339707543 0.1326804468938033 0.8944461072477659 1.0 0.948302714267659 3 Q6ZRS2,Q96L91 2
185
+ Transketolase-like, pyrimidine-binding domain [IPR005475] 0.4286498005267117 0.1324177945162644 0.8946538406233564 1.0 0.948302714267659 4 P11177 1
186
+ ELMO domain [IPR006816] 0.4807421984818582 0.1302904454970496 0.8963366390239258 1.0 0.9494949850160198 2 Q8IZ81 1
187
+ FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.2848686555846325 0.1238195308899345 0.9014581674005072 1.0 0.9538529044029213 11 Q96AY3,Q9Y680,Q9NWM8 3
188
+ Rho GTPase-activating protein domain [IPR000198] 0.3126902125350238 0.1157471107528299 0.9078529681644598 1.0 0.9581205609762417 7 Q68EM7 1
189
+ Immunoglobulin I-set [IPR013098] 0.3528146649235953 0.1127871781463677 0.9101992838322062 1.0 0.9602399576833082 5 O75962,Q92859,P10586 3
190
+ DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133] 0.4710348706411806 0.1057564567466772 0.9157755854556184 1.0 0.9637347316788166 3 Q07864,P09884 2
191
+ DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134] 0.4710348706411806 0.1057564567466772 0.9157755854556184 1.0 0.9637347316788166 3 Q07864,P09884 2
192
+ Plectin/S10, N-terminal [IPR005326] 0.4543154343547848 0.0952500692532157 0.9241162012212798 1.0 0.9680925648958963 2 P46783 1
193
+ Dynein heavy chain, tail [IPR013594] 0.4520663480461013 0.0926714081096121 0.9261646122613204 1.0 0.9680925648958963 2 Q8NCM8 1
194
+ Dynein heavy chain, linker [IPR013602] 0.4520663480461013 0.0926714081096121 0.9261646122613204 1.0 0.9680925648958963 2 Q8NCM8 1
195
+ Dynein heavy chain AAA lid domain [IPR041658] 0.4520663480461013 0.0926714081096121 0.9261646122613204 1.0 0.9680925648958963 2 Q8NCM8 1
196
+ Dynein heavy chain, ATP-binding dynein motor region [IPR035706] 0.4520663480461013 0.0926714081096121 0.9261646122613204 1.0 0.9680925648958963 2 Q8NCM8 1
197
+ Dynein heavy chain region D6 P-loop domain [IPR004273] 0.4520663480461013 0.0926714081096121 0.9261646122613204 1.0 0.9680925648958963 2 Q8NCM8 1
198
+ Dynein heavy chain, coiled coil stalk [IPR024743] 0.4520663480461013 0.0926714081096121 0.9261646122613204 1.0 0.9680925648958963 2 Q8NCM8 1
199
+ Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699] 0.4520663480461013 0.0926714081096121 0.9261646122613204 1.0 0.9680925648958963 2 Q8NCM8 1
200
+ Dynein heavy chain, AAA module D4 [IPR024317] 0.4520663480461013 0.0926714081096121 0.9261646122613204 1.0 0.9680925648958963 2 Q8NCM8 1
201
+ Dynein heavy chain, C-terminal domain [IPR041228] 0.4520663480461013 0.0926714081096121 0.9261646122613204 1.0 0.9680925648958963 2 Q8NCM8 1
202
+ PTB/PI domain [IPR006020] 0.4391341017711361 0.0790138360074328 0.937021617929232 1.0 0.9759555037240236 2 Q9Y3P9 1
203
+ RNA recognition motif domain, eukaryote [IPR003954] 0.262836752503392 0.0779280937322974 0.9378852517919556 1.0 0.9759555037240236 14 Q14011,P31483 2
204
+ Ubiquitin-activating enzyme E1, C-terminal [IPR018965] 0.4377284228282196 0.0776465061635735 0.9381092474549886 1.0 0.9759555037240236 2 P22314 1
205
+ Ubiquitin-activating enzyme E1, FCCH domain [IPR032418] 0.4377284228282196 0.0776465061635735 0.9381092474549886 1.0 0.9759555037240236 2 P22314 1
206
+ Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420] 0.4377284228282196 0.0776465061635735 0.9381092474549886 1.0 0.9759555037240236 2 P22314 1
207
+ Ubiquitin-activating enzyme, SCCH domain [IPR019572] 0.4377284228282196 0.0776465061635735 0.9381092474549886 1.0 0.9759555037240236 2 P22314 1
208
+ Suppressor of forked [IPR008847] 0.4354793365195374 0.0755053125060824 0.9398126708363246 1.0 0.9769648554813916 2 Q14690 1
209
+ RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209] 0.4337925217880172 0.0739366551704503 0.9410607890474564 1.0 0.9770455032387576 2 Q9UJK0 1
210
+ DALR anticodon binding [IPR008909] 0.4335113859994303 0.0736782922165252 0.9412663721342398 1.0 0.9770455032387576 2 Q5T160 1
211
+ Arginyl-tRNA synthetase, catalytic core domain [IPR035684] 0.4335113859994303 0.0736782922165252 0.9412663721342398 1.0 0.9770455032387576 2 Q5T160 1
212
+ Acyl transferase [IPR014043] 0.4315434354793298 0.0718942146221573 0.9426860941996976 1.0 0.9781616761151412 2 Q8IVS2 1
213
+ Chaperone DnaJ, C-terminal [IPR002939] 0.3056571911061109 0.0706454936672001 0.9436799021281564 1.0 0.9786494053602453 6 Q9UBS4,P31689,Q9UDY4,Q96EY1,O60884 5
214
+ Syntaxin, N-terminal domain [IPR006011] 0.4307782219990888 0.0649822729095536 0.9481881145881336 1.0 0.982309696718136 3 O15400 1
215
+ Potassium channel tetramerisation-type BTB domain [IPR003131] 0.428008998875146 0.0627596254747957 0.9499579166605407 1.0 0.98355103292597 3 Q96CX2,Q9H3F6 2
216
+ Armadillo repeat-containing domain [IPR006911] 0.4188923249929723 0.0614182548866199 0.9510261145067668 1.0 0.9840087783271172 2 Q96D09 1
217
+ Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.2979160880114291 0.0611643821899253 0.9512282954952984 1.0 0.9840087783271172 6 Q15019 1
218
+ Class II aldolase/adducin N-terminal [IPR001303] 0.3696682476364135 0.0604641651753872 0.9517859556565462 1.0 0.9840087783271172 4 P35611 1
219
+ CRA domain [IPR013144] 0.3680833493114903 0.059075291963536 0.9528921384197668 1.0 0.9844356759229312 4 Q7L5Y9,Q9NWU2 2
220
+ CTLH/CRA C-terminal to LisH motif domain [IPR024964] 0.3680833493114903 0.059075291963536 0.9528921384197668 1.0 0.9844356759229312 4 Q7L5Y9,Q9NWU2 2
221
+ Glycosyl transferase, family 1 [IPR001296] 0.4201325757342358 0.0568165026595836 0.9546913679517836 1.0 0.9858354623500108 3 Q2TAA5 1
222
+ D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139] 0.360056258790439 0.0524400380636166 0.9581780722269828 1.0 0.9871696795020396 4 Q13363,P56545,O43175 3
223
+ D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140] 0.360056258790439 0.0524400380636166 0.9581780722269828 1.0 0.9871696795020396 4 Q13363,P56545,O43175 3
224
+ NAD-dependent epimerase/dehydratase [IPR001509] 0.4135456822837799 0.052262795059863 0.958319298023635 1.0 0.9871696795020396 3 Q9NRG7 1
225
+ Cyclin-like [IPR013763] 0.269212319785861 0.0511565164087919 0.9592008013254508 1.0 0.9873614627634216 7 Q00403 1
226
+ R3H domain [IPR001374] 0.3575985144916622 0.0505387751341121 0.9596930507804572 1.0 0.9875102406581514 4 O15226 1
227
+ Serine-tRNA ligase catalytic core domain [IPR033729] 0.4017430418892285 0.0497784548677573 0.9602989359189192 1.0 0.9877757979028364 2 Q9NP81 1
228
+ CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.4073696158121834 0.0483232765931544 0.9614586041821448 1.0 0.9879290575517224 3 Q7L576 1
229
+ Chromo domain [IPR023780] 0.24766507598342 0.0482819753426649 0.9614915193918876 1.0 0.9879290575517224 8 Q13185,P83916,Q14781,P45973 4
230
+ Zinc finger, ZZ-type [IPR000433] 0.3527426160337615 0.0469565804067224 0.9625478331455892 1.0 0.9882992936129694 4 Q9P0J7,P46939,O43149 3
231
+ Ubiquitin conjugation factor E4, core [IPR019474] 0.381782400899634 0.0394935101204179 0.9684969276555276 1.0 0.9940481657179971 2 Q14139 1
232
+ LEM domain [IPR003887] 0.2762066797369633 0.0390525014712441 0.9688485303898802 1.0 0.994049792741062 6 P50402 1
233
+ GTP binding domain [IPR006073] 0.2446673548646336 0.038060750304144 0.9696392453396756 1.0 0.9943820784369344 13 Q8N3Z3 1
234
+ YTH domain [IPR007275] 0.3863892013498413 0.0371465947923793 0.9703681203732706 1.0 0.9943820784369344 3 Q9H6S0,Q96MU7 2
235
+ Band 4.1, C-terminal [IPR008379] 0.3838582677165427 0.0360114875584892 0.9712731991493156 1.0 0.9943820784369344 3 Q9Y2J2,O43491 2
236
+ FERM adjacent (FA) [IPR014847] 0.3838582677165427 0.0360114875584892 0.9712731991493156 1.0 0.9943820784369344 3 Q9Y2J2,O43491 2
237
+ SAB domain [IPR007477] 0.3838582677165427 0.0360114875584892 0.9712731991493156 1.0 0.9943820784369344 3 Q9Y2J2,O43491 2
238
+ Zinc finger, UBR-type [IPR003126] 0.381608548931388 0.0350382658882316 0.9720492278284764 1.0 0.9945771091925628 3 Q8N806,Q5T4S7 2
239
+ Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.3807649043869558 0.0346818370819332 0.972333444122952 1.0 0.9945771091925628 3 P31689,Q96EY1 2
240
+ Cullin homology domain [IPR016158] 0.2454013998932638 0.0286057140889195 0.9771790547668208 1.0 0.9945771091925628 7 Q13619 1
241
+ Cullin, N-terminal [IPR001373] 0.2454013998932638 0.0286057140889195 0.9771790547668208 1.0 0.9945771091925628 7 Q13619 1
242
+ EF hand associated, type-1 [IPR013566] 0.3427045262861975 0.0272717394692667 0.9782429971184008 1.0 0.9945771091925628 2 Q8IXI1 1
243
+ MIRO domain [IPR020860] 0.3427045262861975 0.0272717394692667 0.9782429971184008 1.0 0.9945771091925628 2 Q8IXI1 1
244
+ EF hand associated, type-2 [IPR013567] 0.3427045262861975 0.0272717394692667 0.9782429971184008 1.0 0.9945771091925628 2 Q8IXI1 1
245
+ Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871] 0.3405511811023667 0.0223672561792172 0.9821549995977004 1.0 0.9945771091925628 3 Q10570,Q16531 2
246
+ Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846] 0.3405511811023667 0.0223672561792172 0.9821549995977004 1.0 0.9945771091925628 3 Q10570,Q16531 2
247
+ EF-hand, Ca insensitive [IPR014837] 0.3383014623172151 0.0219078778304216 0.9825214406843136 1.0 0.9945771091925628 3 O43707,P12814 2
248
+ Cullin protein, neddylation domain [IPR019559] 0.2526388850625677 0.0218230296305782 0.9825891235714974 1.0 0.9945771091925628 6 Q13619 1
249
+ Clp ATPase, C-terminal [IPR019489] 0.3010964295754905 0.0217213911355179 0.982670200138849 1.0 0.9945771091925628 2 Q9H078 1
250
+ Acyl-CoA-binding protein, ACBP [IPR000582] 0.3276152980877428 0.0199883723134781 0.9840526482635032 1.0 0.9956214895149088 3 Q9H3P7,Q5T8D3 2
251
+ Fibronectin type III [IPR003961] 0.2314937048825233 0.0190278683984949 0.9848188736645792 1.0 0.9957183995620112 7 P10586 1
252
+ DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.2476780185758541 0.0189892985603214 0.9848496423836934 1.0 0.9957183995620112 6 Q9HCE1,O60306,P38935,P42694,Q92900 5
253
+ DNA2/NAM7 helicase, helicase domain [IPR041677] 0.2476083286437919 0.0170646758168813 0.986385019421374 1.0 0.9965023057979984 5 O60306,P42694,P38935,Q92900 4
interpro_domain/selections.json ADDED
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interpro_family/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Mitochondrial carrier protein [IPR002067]"}
interpro_family/advanced/plot_0.png ADDED

Git LFS Details

  • SHA256: e46be7b81206238106ea70068c64725ac3b59cba3c35750453fd37e5f10d0429
  • Pointer size: 131 Bytes
  • Size of remote file: 193 kB
interpro_family/advanced/plot_1.png ADDED

Git LFS Details

  • SHA256: 8ad618e0572c5d86895fbc8ccefb1f073dd6b0c55a2089dfcd2057f82fc6a972
  • Pointer size: 131 Bytes
  • Size of remote file: 188 kB
interpro_family/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Mitochondrial carrier protein [IPR002067]", "2": "Short-chain dehydrogenase/reductase SDR [IPR002347]", "3": "Small GTPase [IPR001806]", "4": "Syntaxin [IPR045242]", "5": "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "6": "Importin beta family [IPR040122]"}
interpro_family/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: 86b9230bd43a941a8891f430c4217812a75b5c3c67425542449a0c93c02249a3
  • Pointer size: 131 Bytes
  • Size of remote file: 147 kB
interpro_family/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: 605fb5c528e96378b0dee802bf5745554cb4395b36211daeff70d3a2cb41b30c
  • Pointer size: 131 Bytes
  • Size of remote file: 135 kB
interpro_family/basic/plot_2.png ADDED

Git LFS Details

  • SHA256: ec44147fa6badd03d9f07d9c1edb15c84f2eab77adead31920e4311defa68812
  • Pointer size: 131 Bytes
  • Size of remote file: 152 kB