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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Electron transport chain oxphos system in mitochondria 0.6015343386494284 3.106980604108558 0.0018900879930421 0.682245795452864 0.3817977745945111 51 O14949,P21912,P14406,P56556,Q9Y6N1,P13073,O75964,Q9UDW1,O75380,P14927,P51970,P06576,Q9UII2,P36542,P03886,O95168,O75489,O75947,O43676,P56385 20
Cholesterol biosynthesis with skeletal dysplasias 0.8940400202420458 2.32244593990277 0.0202089361268003 0.9999957646885363 0.922941275629456 5 Q16850,Q15392,Q9UBM7 3
Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.829554616887738 2.261654841838044 0.0237187368221909 0.9999995186927932 0.922941275629456 7 P48506,P09601,Q14145 3
Oxidation by cytochrome p450 0.8157189839239152 2.2018453032943186 0.0276762377271622 0.999999958941312 0.922941275629456 6 O43169,Q6UW02 2
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.8031176170491874 2.1483134348870863 0.0316888643274619 0.9999999966499958 0.922941275629456 6 P48506,P09601,Q14145 3
Nonalcoholic fatty liver disease 0.4640278827025299 2.144541253164419 0.0319895436832344 0.9999999972247032 0.922941275629456 53 O14949,P31751,P13073,Q9P0J0,Q9UDW1,P21912,O75380,P14406,P56556,Q86Y39,P14927,O43676,O95168,O75489,P51970 15
Transcriptional activation by nrf2 in response to phytochemicals 0.8424138880039643 2.113220351892661 0.0345819121457868 0.9999999994535488 0.922941275629456 5 P48506,P09601,Q14145 3
Triacylglyceride synthesis 0.8326885976359913 2.048191732192983 0.0405412162528944 0.999999999987178 0.922941275629456 4 Q9HCL2 1
Sphingolipid metabolism in senescence 0.762397608305316 1.9963363536701029 0.0458973235319648 0.9999999999995688 0.922941275629456 13 Q06136,Q16739,P04062,P16278,Q96G23 5
Metabolism of spingolipids in er and golgi apparatus 0.8056805399324827 1.961410915730916 0.0498311076669337 0.9999999999999648 0.922941275629456 5 Q06136,O95470,Q16739,Q9NRA0 4
Familial partial lipodystrophy fpld 0.7447610331413779 1.894421326833686 0.0581691078501738 0.9999999999999998 0.922941275629456 8 O75844,P49354,O60725 3
Mitochondrial complex i assembly model oxphos system 0.6560274736347518 1.855594550403656 0.0635113710449994 1.0 0.922941275629456 31 Q96CU9,Q8N183,Q7L592,Q9P0J0,Q9Y375,O75380,Q8TB37,P56556,P03886,Q9P032,O43676,O95168,O75489,P51970 14
Riboflavin and coq disorders 0.7343548681831227 1.8505379629764809 0.0642360516969409 1.0 0.922941275629456 6 Q86YH6,Q8NI60 2
Mitochondrial complex iv assembly 0.7316491761372685 1.842103104569409 0.0654600697842124 1.0 0.922941275629456 11 Q9Y2R0,P13073,P14406,P00403,Q96I36,Q9Y6N1,P15954 7
Relationship between inflammation cox2 and egfr 0.7760100746238489 1.81014429399562 0.0702734135854661 1.0 0.922941275629456 4 Q9H7Z7 1
Thiamine metabolic pathways 0.7132246427701399 1.7571913399400707 0.0788852008737301 1.0 0.922941275629456 6 O14874,P12694 2
Glycosaminoglycan degradation 0.7008487560368569 1.6990011343210605 0.0893189698881085 1.0 0.922941275629456 7 P54802,P16278 2
Sphingolipid metabolism integrated pathway 0.6950194895838527 1.672583165842945 0.0944093831695158 1.0 0.922941275629456 11 Q06136,Q16739,Q9NRA0,Q13510,O15269,O95470,Q8N5B7,Q96G23 8
Sphingolipid metabolism overview 0.6920288904181342 1.6567597436721242 0.0975680588662206 1.0 0.922941275629456 10 Q06136,Q16739,Q9NRA0,Q13510,O15269,O95470,Q96G23 7
Mitochondrial complex iii assembly 0.6859278875685775 1.6285093079131672 0.1034169372092386 1.0 0.922941275629456 10 Q9UDW1,P14927,O14949 3
Nephrotic syndrome 0.671481934887749 1.568668739120237 0.1167251463333209 1.0 0.922941275629456 13 Q9BT22,Q14108,O75844,Q86YH6,P11047 5
Vitamin b12 disorders 0.7143188496819941 1.5455572104797484 0.1222115419955409 1.0 0.922941275629456 4 P22033,Q9NPF0 2
Aryl hydrocarbon receptor pathway wp2586 0.6621651944185913 1.517919074008828 0.1290348008727051 1.0 0.922941275629456 10 P24941,O00170 2
Vitamin a and carotenoid metabolism 0.7008187536807654 1.5158983880599757 0.1295450479792164 1.0 0.922941275629456 5 Q8WTV0 1
Sphingolipid pathway 0.656710573052724 1.4928330048639362 0.1354809054947634 1.0 0.922941275629456 11 Q06136,P04062,Q96G23,Q16739 4
Vitamin d metabolism 0.8405940272874095 1.4891695846368789 0.1364427178542409 1.0 0.922941275629456 3 P04062 1
Ketogenesis and ketolysis 0.6882199794508801 1.4613734667385794 0.1439129781724899 1.0 0.922941275629456 5 O43772 1
Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.6416086574983614 1.4300156131747643 0.1527125380002485 1.0 0.922941275629456 7 P22466 1
Estrogen receptor pathway 0.8228559952848424 1.4221060392454612 0.1549954698530737 1.0 0.922941275629456 3 Q9HCL2 1
Allograft rejection 0.6268567070016969 1.3513890123263663 0.1765708516588002 1.0 0.922941275629456 11 P08183,P10321,P01889,P04439,Q9BY49 5
7oxoc and 7betahc pathways 0.6230188917663284 1.3341355822101628 0.1821594263766015 1.0 0.922941275629456 10 P34913,O15118,Q9UBM7 3
Degradation pathway of sphingolipids including diseases 0.62004643878462 1.3310249113003991 0.183180814219372 1.0 0.922941275629456 7 O43681,P16278,P17900 3
Acquired partial lipodystrophy barraquersimons syndrome 0.657077642535168 1.3259995307282917 0.1848398528201067 1.0 0.922941275629456 5 P02545,P49354,O60725 3
Oxysterols derived from cholesterol 0.6134842497701296 1.295713111040967 0.1950743426241996 1.0 0.9382146954782936 8 P34913,Q9UBM7 2
Interactome of polycomb repressive complex 2 prc2 0.6456893515881739 1.2467566626080036 0.2124867353769732 1.0 0.9598472812625688 4 Q9Y2W1,Q9NYF8 2
Nrf2are regulation 0.6019623478896333 1.237857002728496 0.2157690877997056 1.0 0.9598472812625688 9 P48506,P09601,Q14145 3
Nuclear receptors metapathway 0.4027557582920523 1.1971826819520783 0.2312353584042408 1.0 0.9731154666178468 50 P08183,O00170,Q9HCL2,P04150,P48507,O14880,Q15067,P23786,P09601,Q14145,P48506,P27105 12
Oxidative phosphorylation 0.5413715616289032 1.1621606883123554 0.2451701996767767 1.0 1.0 31 O75964,O75947,O75380,P03886,P56556,Q86Y39,O95168,P56385,O75489,P51970,P06576 11
Lung fibrosis 0.5795859400941671 1.1520043949338128 0.2493192673428312 1.0 1.0 6 P09601 1
Copper homeostasis 0.5809203080483214 1.144377799907363 0.2524669908806973 1.0 1.0 8 Q9Y6N1,P35670 2
Oxidative stress response 0.5728800373966185 1.1213091392938936 0.2621562966478552 1.0 1.0 6 P48506,P09601 2
Influence of laminopathies on wnt signaling 0.576411505536435 1.1110286371521176 0.2665560229797949 1.0 1.0 11 O75844,P49354,P50402,O60725 4
Mitochondrial long chain fatty acid betaoxidation 0.5753100787899528 1.103517755619715 0.2698023852014273 1.0 1.0 13 Q16836,O43772,P23786,Q9BY49,P49748 5
Statin inhibition of cholesterol production 0.5548091240745825 1.03869840145263 0.2989450248535799 1.0 1.0 6 P37268,Q8WTV0 2
S1p receptor signal transduction 0.5518668374622676 1.0033210453155148 0.3157059851535713 1.0 1.0 9 Q9H0H5,P31751,Q9NRA0 3
Progeriaassociated lipodystrophy 0.5533805937896056 0.99875264948321 0.3179145289575826 1.0 1.0 12 O75844,Q14191,O60725 3
Intracellular trafficking proteins involved in cmt neuropathy 0.5492730783900289 0.9790946679581548 0.3275332059786948 1.0 1.0 12 Q8TB36,P50570,Q9NR77 3
Proximal tubule transport 0.5470340330993617 0.9755111241643576 0.329306786408954 1.0 1.0 10 P08183,P36543 2
Irinotecan pathway 0.8772127001966799 0.9704686622064908 0.3318129380636816 1.0 1.0 2 O15118 1
Overlap between signal transduction pathways contributing to lmna laminopathies 0.5399409877443484 0.9335279435129824 0.3505474496830145 1.0 1.0 16 P49354,P55209,O75844,P42166,O60725,P50402 6
Cholesterol metabolism with bloch and kandutschrussell pathways 0.5104438367350325 0.866346543857947 0.3863001492688305 1.0 1.0 26 Q15800,Q9UBM7,O76062,P37268,Q9BWD1,Q14739,Q16850,Q15392 8
Mitochondrial immune response to sarscov2 0.5207297461319389 0.8589055677859074 0.3903926173614085 1.0 1.0 9 Q9Y375,Q9Y6M9,Q99623 3
Vitamin d receptor pathway 0.5246874051249578 0.8572848402423243 0.3912874845881933 1.0 1.0 15 P08183,P11413,Q96KA5,P24941,P49427 5
Urea cycle and related diseases 0.8423714526552357 0.8469092868331973 0.3970456857124889 1.0 1.0 2 Q9UJS0 1
Nad metabolism 0.5519161538905989 0.8408242252678559 0.4004464136098002 1.0 1.0 4 P43490 1
Endochondral ossification with skeletal dysplasias 0.5118220514698919 0.834250027377971 0.4041401054901321 1.0 1.0 7 P50454,Q96QD8,Q9Y376,Q01581 4
Endochondral ossification 0.5118220514698919 0.834250027377971 0.4041401054901321 1.0 1.0 7 P50454,Q96QD8,Q9Y376,Q01581 4
Ferroptosis 0.4992071676453441 0.8196890045947395 0.4123934197722474 1.0 1.0 27 P45880,P04035,Q96QD8,P37268,P09601,P48506,Q9Y277 7
Vitamin b12 metabolism 0.5100354863542718 0.8175096211382902 0.4136372533223702 1.0 1.0 8 P22033,Q8WTV0,P04179 3
Hematopoietic stem cell differentiation 0.8325372295588549 0.8126605931773266 0.4164126806215082 1.0 1.0 2 P36896 1
Camkk2 pathway 0.511727340806667 0.79546756778955 0.4263415694538071 1.0 1.0 14 P42345,Q9Y3D6,Q14012,P09601,O76024,O00429 6
Cellular proteostasis 0.4963138982128005 0.7746936632765467 0.4385206962807433 1.0 1.0 6 Q99471,O15212 2
Striated muscle contraction pathway 0.4929715447286767 0.7598934129245158 0.4473182993270246 1.0 1.0 6 P08670 1
Cholesterol biosynthesis pathway 0.4958395214382744 0.72004586416953 0.4714967573399584 1.0 1.0 14 P37268,Q15800,Q16850,Q9UBM7 4
Endothelin pathways 0.4844839856317909 0.6943099572964871 0.4874878478508444 1.0 1.0 9 P42892,Q05682,P00403,O76075 4
Nocgmppkg mediated neuroprotection 0.4686821252810678 0.6431270199313837 0.5201416832464445 1.0 1.0 7 P30536,P07196 2
Onecarbon metabolism and related pathways 0.4728116283763808 0.6129754613409584 0.5398925651791489 1.0 1.0 14 P35790,P48506,P48507,Q9HBU6 4
Nad biosynthetic pathways 0.4878772682952086 0.6030763550457936 0.546457895363579 1.0 1.0 5 P43490 1
Arachidonate epoxygenase epoxide hydrolase 0.7673503793200209 0.5953345589971403 0.5516198595593105 1.0 1.0 2 P34913 1
Nad metabolism sirtuins and aging 0.4922023488681359 0.5952224125434395 0.5516948106703841 1.0 1.0 4 P43490 1
Mevalonate pathway 0.4478989123912516 0.5546081357717548 0.5791627229788474 1.0 1.0 7 P04035,Q9BWD1,Q01581 3
Inclusion body myositis 0.5854830564491608 0.5529337502411702 0.5803087757762504 1.0 1.0 3 P05067 1
Ciliopathies 0.4519497622661386 0.5142196015582056 0.6070984648090008 1.0 1.0 21 Q10713,O43924,Q13432 3
Joubert syndrome 0.4516266205424486 0.5126654847337142 0.6081853373856216 1.0 1.0 21 O43924,P41208,Q13432 3
Matrix metalloproteinases 0.7372857544253886 0.5025384276549142 0.6152888284530635 1.0 1.0 2 Q9UGU0 1
Omega3 omega6 fatty acid synthesis 0.4296148392628524 0.4907539407437109 0.6236004902967072 1.0 1.0 6 O15254 1
Congenital generalized lipodystrophy cgl 0.7305422871593028 0.4825300594216811 0.6294294500618571 1.0 1.0 2 P31751 1
Metapathway biotransformation phase i and ii 0.436789456581179 0.4545802580079454 0.6494112402889116 1.0 1.0 24 Q6UW02,O14880,Q16850,P34913,Q86UY6,P0DMN0 6
Amyotrophic lateral sclerosis als 0.4222082469245233 0.4293824382854647 0.6676449320039446 1.0 1.0 9 P07197,O96008,P07196 3
Inflammatory response pathway 0.6920483281820645 0.3748478315316564 0.707773639123235 1.0 1.0 2 P11047 1
Glycerophospholipid biosynthetic pathway 0.405152424732448 0.3731065144884122 0.7090691703490588 1.0 1.0 8 Q9HCL2 1
15q112 copy number variation syndrome 0.4263382439046699 0.3719215561667724 0.7099512550860245 1.0 1.0 5 Q9UGJ1,Q9BSJ2 2
Eicosanoid metabolism via lipooxygenases lox 0.3975136095213836 0.366890510929278 0.713700689820093 1.0 1.0 6 O15254 1
Ovarian infertility 0.6774374824388839 0.3371929078356066 0.7359714832923618 1.0 1.0 2 Q8WXH0 1
Glucocorticoid receptor pathway 0.3837449150177964 0.2850680030100745 0.7755920433068113 1.0 1.0 9 P27105 1
Proteoglycan biosynthesis 0.4044612220116783 0.2840122391603996 0.7764010012070746 1.0 1.0 4 Q8TB61 1
Male infertility 0.3997464047645225 0.2804618055005362 0.7791232248151667 1.0 1.0 23 P08183,P41440,Q15165 3
Burn wound healing 0.3739503740289229 0.2724814325725586 0.7852518660169747 1.0 1.0 7 P50454,P08670,P09429 3
Nonhomologous end joining 0.3672648570645014 0.2617314142377712 0.7935285194769983 1.0 1.0 6 Q14191 1
Type i collagen synthesis in the context of osteogenesis imperfecta 0.3815451195821299 0.2508027963195444 0.8019665795147053 1.0 1.0 12 P50454,P13674,Q96AY3,O15460 4
Folate metabolism 0.3850476076261679 0.2369569058129728 0.8126902223861348 1.0 1.0 16 P41440,Q8WTV0,P13995,P00374 4
Eicosanoid metabolism via cyclooxygenases cox 0.3564563544931485 0.2274391461457648 0.8200822835362376 1.0 1.0 6 O15254 1
Neuroinflammation 0.3564266771599745 0.2273475893117079 0.8201534708547569 1.0 1.0 6 P00403 1
Heme biosynthesis 0.3742003266581871 0.2090347636543227 0.8344211005629627 1.0 1.0 5 P22830,P50336 2
Hostpathogen interaction of human coronaviruses interferon induction 0.3531232414181262 0.2061544243003013 0.8366702872474563 1.0 1.0 7 O15111,Q13546,Q9Y6K9,Q7Z434,Q16539,P42224 6
Fatty acid betaoxidation 0.3761832089935955 0.1921656716441712 0.8476124347933167 1.0 1.0 19 Q16836,P49748,O43772,P23786 4
Mevalonate arm of cholesterol biosynthesis pathway 0.3631670657193997 0.1896720547861709 0.8495661203181815 1.0 1.0 12 Q9BWD1 1
Adipogenesis 0.3635531526166633 0.157571547542447 0.8747944252123792 1.0 1.0 17 P43490,P14174,O75844 3
Genes related to primary cilium development based on crispr 0.3592300420431032 0.1554557087171955 0.8764620687073343 1.0 1.0 15 Q10713,O95684 2
Sting pathway in kawasakilike disease and covid19 0.4280494659921392 0.1438034504679846 0.8856556781192466 1.0 1.0 3 O15111,Q04206 2
Canonical nfkb pathway 0.4280494659921392 0.1438034504679846 0.8856556781192466 1.0 1.0 3 O15111,Q04206 2
Altered glycosylation of muc1 in tumor microenvironment 0.4280494659921392 0.1438034504679846 0.8856556781192466 1.0 1.0 3 O15111,Q04206 2
Tryptophan metabolism 0.3487594356377302 0.138105255578077 0.890157232230582 1.0 1.0 13 Q15392 1
Kisspeptinkisspeptin receptor system in the ovary 0.3167705980493968 0.1188646366771782 0.9053825989271584 1.0 1.0 6 P31751 1
Spinal cord injury 0.3558307052264802 0.1160894197440999 0.9075816739395132 1.0 1.0 21 P62942,Q9NQC3,P24941,P06493,P14174 5
Krebs cycle disorders 0.3128868880135186 0.0997165914012042 0.920569328161838 1.0 1.0 7 P07954,O00330,Q96I99,P36957,Q9P2R7,Q96HY7 6
Cohesin complex cornelia de lange syndrome 0.3447669047493125 0.0945117779836394 0.9247026268477556 1.0 1.0 18 Q7Z5K2,Q14674,Q9UQE7,Q96GD4,P06493,P53350 6
Mitochondrial gene expression 0.3017249829863152 0.0854427664700184 0.9319093947246088 1.0 1.0 6 O00411,Q00059 2
Proteasome degradation 0.3160885203066197 0.0852923550858488 0.932028969144421 1.0 1.0 42 Q9UL46,P10321,O43242,O00231,P01889,P04439,P28070,P46934,P28072,P49721,P25787 11
Hedgehog signaling pathway wp4249 0.3145226137861591 0.0753591381872037 0.9399289697257878 1.0 1.0 4 P48729 1
Photodynamic therapyinduced nfkb survival signaling 0.5248665355436797 0.0731934288833967 0.9416521953555452 1.0 1.0 2 O15111 1
Disruption of postsynaptic signaling by cnv 0.3020833333333226 0.0580810396700392 0.9536840770457752 1.0 1.0 9 Q06787,P27361,Q14168,Q13555,P28482,Q12959,Q7L576,Q07157 8
Ethanol effects on histone modifications 0.3080856221417352 0.0531924155063461 0.9575785986109876 1.0 1.0 11 P00374 1
Vasopressinregulated water reabsorption 0.3265794520097658 0.0456291033496367 0.9636058722058016 1.0 1.0 18 Q13561 1
Molybdenum cofactor moco biosynthesis 0.4782242202865914 0.0390224397366501 0.9688724979144792 1.0 1.0 2 Q9NQX3 1
Cannabinoid receptor signaling 0.2736197472440228 0.0349003697999246 0.9721591857364976 1.0 1.0 6 Q8NCG7 1
Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.2868806306306294 0.0301660460763746 0.975934627506602 1.0 1.0 9 P20339,Q8WUM4,P61020,P51148,P31943,P27361,O14964,P28482 8
Pyrimidine metabolism and related diseases 0.2810724955752317 0.0291128664727949 0.9767745741867332 1.0 1.0 8 Q05682,Q9H0P0,O76075 3
Dna damage response 0.3293835253330825 0.0240768043518267 0.9807913454043262 1.0 1.0 26 O95067,P24941,P41440,P06493 4
Mirna regulation of dna damage response 0.329196704674857 0.0225791876026682 0.9819859454827138 1.0 1.0 27 O95067,P24941,P41440,P06493 4
Nanoparticle triggered regulated necrosis 0.3105677346824129 0.0225281015760687 0.9820266958691016 1.0 1.0 3 P09874,Q13546 2
Nephrogenesis 0.4206237707221089 0.0177477989962059 0.985840048557159 1.0 1.0 2 O95747 1
Mammary gland development pathway embryonic development stage 1 of 4 0.3838156785613943 0.011840944456331 0.9905525140022836 1.0 1.0 2 P23229 1
Reninangiotensinaldosterone system raas 0.3821298117448748 0.0116628056892343 0.9906946383595504 1.0 1.0 2 Q14012 1
Sars coronavirus and innate immunity 0.3537510536667601 0.009504006775756 0.992417013885014 1.0 1.0 2 Q7Z434 1
Leptininsulin signaling overlap 0.3419499859511095 0.0089673437294369 0.9928451907772464 1.0 1.0 2 O14654 1
Somatroph axis gh and its relationship to dietary restriction and aging 0.339702163529086 0.0088829765914162 0.9929125033330308 1.0 1.0 2 P42345 1
P53 transcriptional gene network 0.2602629974569831 0.0079636852211313 0.993645965677478 1.0 1.0 7 P04066 1
Nrp1triggered signaling pathways in pancreatic cancer 0.2873921275884956 0.0070610740240729 0.994366124869889 1.0 1.0 12 P24941 1
Translation factors 0.3135853060069489 0.0034369588870627 0.9972577089668702 1.0 1.0 37 O75153,Q9NR50 2