diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d399302b59fed07f5544145eb6912328f99d9021 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:199dc52c8965e0b13118bec1a29c6ebe93cce913df107ba8f7e5ff6feea9a8d0 +size 92599 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..7cb8edb62dc7994c11afb4ef3e35ecb95f5d5d69 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 55, + "title": "Average number of proteins per term", + "value": 2.909090909090909 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8e2a8b52e2f107ab5f7f27a42d0768376b04bd67 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ffebfaa6240f4ccee605ed6199b5af4a8419eae6 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Histidine acid phosphatase active site [IPR033379] 0.8721550997471134 2.3231335977827 0.020171976578494 0.6739816126166339 0.0396235254220418 2 Q9NPH0 1 +Serine carboxypeptidase, serine active site [IPR018202] 0.9277684092186628 2.076348891847288 0.0378616944645537 0.8803086394197494 0.0631028241075896 3 Q9H3G5,Q9HB40 2 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..28bc6f0d1299404c56ea56719749cfc3db6e2a54 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ACVR1B", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP8", "CDC34", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME3", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCD", "PRKCZ", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN9", "PTPRF", "RIPK1", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UBE2T", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["ACP6", "CPVL", "SCPEP1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8b16c741871518e676e1803939b0b4f4e9cbcc8f --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3cfe098179c49d9e1d4b46809b2f760a4da407a78e883c9654c156dadb7b209a +size 130463 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..049489c851ac4594b2485c113a9043cd1e881054 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1725e5a8fb46a1d7b178ae35d457504e644525755436d4bfc87cfae6cf0d2490 +size 84987 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..07ce12279a92d0b07af11a680f38336075a94350 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 5.096774193548387 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..614ffdd4a42bd5d10e77656ef89e602c813eaea3 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..21fef9d21e2ff9fa54c597ef514abfb92dc441b3 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EF-Hand 1, calcium-binding site [IPR018247] 0.425800445207549 1.463559378921775 0.1433143783189856 0.9917307558391544 0.2221372863944277 41 Q9BRK5,Q9H223,Q9Y680,Q9NWM8,P80303,O43852,O95202,Q9UBC2,Q6NUK1,Q14257,Q02818,P41208 12 +Peptidase M16, zinc-binding site [IPR001431] 0.4492122132137389 0.2827713913026965 0.777352086084278 1.0 0.8236346925983589 5 P22695,Q10713 2 +2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016] 0.3722237840877133 0.0850375913516605 0.9322315053556424 1.0 0.9322315053556424 4 O00330,P36957,P11182 3 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..93de66ec59abe15a87c5b59fff2b971e61073f47 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ACVR1B", "ADSS", "AKT2", "APEX1", "AURKA", "AURKB", "BPNT1", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CEP97", "CETN2", "CHUK", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO9B", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN1", "PKN2", "PLCD3", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA2", "PRKACA", "PRKCD", "PRKCSH", "PRKCZ", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "USP32", "VRK1", "YES1"], "leading_proteins": ["CALU", "CETN2", "DBT", "DLST", "EHD4", "EPS15L1", "FKBP14", "FKBP7", "LETM1", "NUCB1", "NUCB2", "PDHX", "PMPCA", "RCN2", "SDF4", "SLC25A24", "UQCRC2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..cd33ace3491c1b09d40ec60283f1e5855a9e0234 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Intermediate filament protein, conserved site [IPR018039]", "1": "ABC transporter-like, conserved site [IPR017871]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7062d16f8150d6f3b52e23f5e298f42f6de11671 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ccc435d47e75997981fa738c70ba5984d20e15cb270c23ac397bd9038188997e +size 139324 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..38d09a705291614794c6fb38b6768410035f0f66 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27b2f308d769843b5b606277c9852e42ccd168b0841265754510d028df9f5500 +size 141395 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b71eb926c4b460f632225603894754e9b8a5ffba --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a224e686c2c140cb832ebbc5139fc71dc1ba2501ab06664f91fff2b9d27e6ec +size 141952 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..187e38302cd44da3f71a74d84951f4324b5faa16 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Thioredoxin, conserved site [IPR017937] 2 10 2.3181246913992624 0.0204425453492913 3.905339805825242 10.99514563106796 0.4926509002179139 0.4659055513701703 2.3960466288532025 1.0404329420711995 1.0069927416530815 0.3218319873274993 0.2164578169597442 1.0 0.1241196507421894 0.0039601236721776 0.0270223565022924 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..d54f11de774d0f7ef75d3b9e9b6521e1c8933343 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 291, + "title": "Average number of proteins per term", + "value": 2.7938144329896906 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5fc33d0683c607a4ae1cb08e42b6eaf4af382bb3 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e65afa9a4a67360362d9ce212d09e00876fd8890 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,31 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Haem oxygenase conserved site [IPR018207] 0.9820174206237696 2.795865051999782 0.0051761008437225 0.7791247217649195 0.0169241050058793 2 P30519 1 +Tetraspanin, conserved site [IPR018503] 0.9634728856420324 2.7177135418341054 0.0065734722105679 0.853275006251505 0.0203497916305879 2 O60637 1 +Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.9185164372014608 2.5254825415870568 0.0115539522067251 0.9660129041850168 0.0309524304310509 2 P13473 1 +Sugar transporter, conserved site [IPR005829] 0.8968811463894308 2.4315698871526195 0.0150335477455199 0.9878202413400452 0.037074257575816 2 Q5SR56 1 +Thioredoxin, conserved site [IPR017937] 0.7760078269129387 2.3181246913992624 0.0204425453492913 0.9975469579781784 0.0479740378761595 10 Q9H1E5,Q9H3N1 2 +Sterol reductase, conserved site [IPR018083] 0.9210230466554256 2.049802261347771 0.04038373085878 0.9999938283360692 0.0821794802790558 3 O76062,Q14739 2 +Ribosomal protein L13, conserved site [IPR023563] 0.8064062939027739 2.0292146985862543 0.0424364271006627 0.999996690393138 0.0857569464325893 2 Q9BYD1 1 +Syntaxin/epimorphin, conserved site [IPR006012] 0.8469377926129213 1.9391479601366417 0.0524833241888256 0.9999998462635452 0.0991730346684951 6 O60499,O15400,Q12846,Q9P2W9 4 +Intermediate filament protein, conserved site [IPR018039] 0.7354678288796248 1.912232335039977 0.0558464004114658 0.999999945372404 0.1041750161521574 8 P08670,P20700,Q03252,P07197,P02545,P07196 6 +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.8309540481520041 1.6725352548565264 0.0944188219457085 0.9999999999997076 0.1597607652142787 4 Q8N4Q0 1 +Ribosomal protein L30, conserved site [IPR018038] 0.6920483281820665 1.5017131247540818 0.1331712128295059 1.0 0.2039622259651906 2 P18124 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.7754356379988785 1.4635123801268313 0.1433272285523781 1.0 0.2095890628580001 3 P55899,P01889 2 +ABC transporter-like, conserved site [IPR017871] 0.5789724429845707 1.458201966320708 0.1447848819801573 1.0 0.210662003281129 12 P28288,O14678,Q03518,P08183,Q03519 5 +Calreticulin/calnexin, conserved site [IPR018124] 0.7315688738063812 1.2837183194259447 0.1992405321466654 1.0 0.2722018537778388 3 P27824 1 +Clathrin adaptor complex, small chain [IPR000804] 0.6596577792351123 0.9811649221339108 0.326511419216227 1.0 0.4131079260518351 4 Q92572,P61966 2 +S100/Calbindin-D9k, conserved site [IPR001751] 0.553807249227305 0.8609072427408992 0.389289132311744 1.0 0.4700545124594087 2 P31949 1 +Mini-chromosome maintenance, conserved site [IPR018525] 0.5627453744985192 0.7457145255163394 0.4558398827026106 1.0 0.533354220222033 6 P33993,P33991 2 +Short-chain dehydrogenase/reductase, conserved site [IPR020904] 0.4551362305963256 0.7342798438613114 0.4627781998111206 1.0 0.5386738245801445 11 Q06136,Q9Y394,Q53GQ0,Q6IAN0 4 +Enoyl-CoA hydratase/isomerase, conserved site [IPR018376] 0.5725580530770416 0.7196888187066007 0.4717166121273206 1.0 0.5468905742193239 5 P40939 1 +Guanylate kinase, conserved site [IPR020590] 0.5088108741995458 0.6668936553038606 0.5048400639324742 1.0 0.5806658442859682 7 Q12959 1 +Ribosomal S11, conserved site [IPR018102] 0.49648777746557 0.6132604408836035 0.5397041459859362 1.0 0.6128485479476227 2 P82912 1 +DnaJ domain, conserved site [IPR018253] 0.4240803132026371 0.6105242788261956 0.5415145654231506 1.0 0.6128485479476227 12 Q96KC8,Q9NVH1 2 +Cadherin conserved site [IPR020894] 0.5609341717729915 0.6077545778620981 0.5433502590051087 1.0 0.6128485479476227 3 Q14574 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.4886203989884795 0.5811499906140933 0.5611393689988249 1.0 0.6304693296473284 2 P50570 1 +Heat shock protein Hsp90, conserved site [IPR019805] 0.5314783586284498 0.5032582006567362 0.6147827502741721 1.0 0.676550987862442 3 P07900,P08238 2 +Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.4777965148960158 0.3322065616180217 0.7397332894075173 1.0 0.7856291504291516 3 Q9Y2T2,Q96CW1 2 +Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.401236302332115 0.2738769205448334 0.7841792084291745 1.0 0.8208494591830567 2 P82675 1 +Oxysterol-binding protein, conserved site [IPR018494] 0.4446789041070547 0.2694565952326117 0.7875783393011855 1.0 0.82145267647543 5 Q96SU4 1 +Tyrosine-protein kinase, receptor class V, conserved site [IPR001426] 0.3885923012082075 0.2390002494515617 0.8111053893114049 1.0 0.836991731523471 2 Q15375 1 +Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.3707138842046152 0.0978815143612219 0.9220263788940636 1.0 0.9348769207601828 3 Q16539,P27361 2 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..11e3c9c8831910d9576d3686b21a307ab0a569fe --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Folylpolyglutamate synthetase, conserved site [IPR018109]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARHGEF7", "ARIH2", "ARSA", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BCAT2", "BCR", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD1", "BRD2", "BRD3", "BRPF3", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DIS3L2", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTX3L", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA2", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FPGS", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GMPPB", "GMPR2", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "ISCA2", "ITGA6", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LIG4", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MFSD14B", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP1", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RIOK2", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCAP", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SGSH", "SHPRH", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC4A2", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STMN1", "STOM", "STRN", "STRN3", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM56", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP32", "USP33", "USP34", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", 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sha256:04defa8f25c608b8be76e97f10a4944b21b919a8ede2b54c50c74f8f62067019 +size 135336 diff --git a/interpro_domain/basic/plot_9.png b/interpro_domain/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..a054311c89b8b0ce410015866906b212c68018d1 --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba5364e36d2a7e1789e82d648c75e7a10f917e31e2899fb3d24bbd5e560858fa +size 145583 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..53d637fb35cf6d08676b54c3bcd22f7d50887a26 --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3e72c863f67df51b699978b9fac9c2b88813c88cfa92a68397b33d4115a774f8 +size 732378 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3773e9182aaa3d4070493e73cb88d45a8b1bc047 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Band 7 domain [IPR001107] 5 8 2.056946434709765 0.0396913786697714 3.825242718446602 7.354368932038835 0.2848798017769268 0.3662852929750465 1.8717479731706237 0.7075565364256523 1.25010454777189 0.3076860385713043 0.1451023890450275 1.0 1.0 0.0180927687151257 0.0074566300609561 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 3 8 2.0539743393309315 0.0399781753779207 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0546082347726425 1.0 1.0 0.0145721558996701 0.0193421266882966 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 4 7 2.03612007038049 0.0417382998244963 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0174535696320652 0.0539630923046902 0.1073692926764015 0.000131895504155 0.0001501374850564 +TRAM/LAG1/CLN8 homology domain [IPR006634] 4 5 1.9612057078848584 0.0498550313012557 1.691747572815534 3.3592233009708736 1.3447142040916915 0.1822595206051251 1.014281444620711 0.9789470163478144 1.2723870690026748 0.2262567589818981 0.0005549650281771 0.0451714964804377 0.0903020002145616 0.0014005858473499 5.177174829283688e-05 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8458732d0c69640f5b23fc7bea86850b8f3bb720 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 2840, + "title": "Average number of proteins per term", + "value": 2.2433098591549294 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..03b8d97c2271cf3afa1db605f9ec7e9a5d5d788c --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f6292e02e0f53d033da76bec93380bdbb206b4de --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,238 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +MENTAL domain [IPR019498] 0.9831413318347848 2.800580141157881 0.0051010839581917 0.9999995076886434 0.0151380130002764 2 O95772 1 +Reticulon [IPR003388] 0.9693734194998582 2.742652146010438 0.0060945208963829 0.999999971156984 0.017569570913705 2 O95197 1 +FAD linked oxidase, N-terminal [IPR006094] 0.9491430177015991 2.6568669552968105 0.0078870562420234 0.9999999998287744 0.0214552104668071 2 Q15392 1 +FAD-binding domain, PCMH-type [IPR016166] 0.9491430177015991 2.6568669552968105 0.0078870562420234 0.9999999998287744 0.0214552104668071 2 Q15392 1 +START domain [IPR002913] 0.9438044394492808 2.634096526665872 0.0084361501034941 0.9999999999644577 0.0226025153716259 2 Q14849 1 +Amino acid transporter, transmembrane domain [IPR013057] 0.9317223939308764 2.5823585464237375 0.0098127579397995 0.9999999999993124 0.0252887772677229 2 Q96QD8 1 +Palmitoyltransferase, DHHC domain [IPR001594] 0.9305984827198632 2.5775312570885993 0.0099508881325212 0.9999999999995376 0.025528927096983 2 Q8IUH4 1 +Phospholipase D/Transphosphatidylase [IPR001736] 0.9289126159033408 2.5702857099881857 0.0101614671319258 0.9999999999997472 0.0259053560634376 2 Q8N2A8 1 +Fatty acid desaturase domain [IPR005804] 0.9120539477381264 2.4975259161197956 0.0125063323187399 0.9999999999999996 0.0302856221964331 2 O95864 1 +Acyltransferase, C-terminal domain [IPR032098] 0.9092441697105906 2.4853455388154444 0.0129425739817823 1.0 0.0310446875914373 2 Q92604 1 +Tim44-like domain [IPR007379] 0.8819893228434943 2.3664023424168885 0.0179619123351664 1.0 0.0402301506560509 2 O43615 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8811463894352316 2.362700849670908 0.0181423076444002 1.0 0.0405701997717297 2 Q9NVI7 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.8797415004214599 2.3565286662117435 0.0184466438203685 1.0 0.0410889948626248 2 Q13505 1 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.8797415004214599 2.3565286662117435 0.0184466438203685 1.0 0.0410889948626248 2 Q13505 1 +SUN coiled coil domain 2 [IPR040994] 0.8729980331553782 2.3268495901201356 0.0199732719855902 1.0 0.043633917260828 2 Q9UH99 1 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.8685023883113154 2.307015325535075 0.0210539657568276 1.0 0.0454689715121148 2 Q9Y282 1 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.8685023883113154 2.307015325535075 0.0210539657568276 1.0 0.0454689715121148 2 Q9Y282 1 +MD-2-related lipid-recognition domain [IPR003172] 0.8654116324810297 2.293356980379924 0.0218274612246451 1.0 0.0466792092454761 2 P17900 1 +Peptidase M28 [IPR007484] 0.9583971223149104 2.19607482207248 0.0280865883807357 1.0 0.0569349828702994 3 Q969V3 1 +Arfaptin homology (AH) domain [IPR010504] 0.8426524304579905 2.1922282025412136 0.0283630330161182 1.0 0.0573725169271906 2 P53367 1 +Ribosomal Proteins L2, RNA binding domain [IPR022666] 0.8353470075864009 2.159563107726897 0.030806506982967 1.0 0.0612678430193462 2 P62917 1 +Ribosomal protein L2, C-terminal [IPR022669] 0.8353470075864009 2.159563107726897 0.030806506982967 1.0 0.0612678430193462 2 P62917 1 +Disks large homologue 1, N-terminal PEST domain [IPR019590] 0.8330991851643659 2.1494926631549696 0.0315953670616551 1.0 0.0621945436507933 2 Q12959 1 +PDZ-associated domain of NMDA receptors [IPR019583] 0.8330991851643659 2.1494926631549696 0.0315953670616551 1.0 0.0621945436507933 2 Q12959 1 +CRAL/TRIO, N-terminal domain [IPR011074] 0.8255127844900192 2.1154373050120676 0.0343926931174691 1.0 0.0662205074261779 2 O76054 1 +Tim10-like [IPR004217] 0.8204551840404533 2.092676309506753 0.0363780594426126 1.0 0.0687383159128542 2 Q9Y5J6 1 +Band 7 domain [IPR001107] 0.7669770146684098 2.0569464347097655 0.0396913786697714 1.0 0.0735313212147103 8 O75955,Q14254,Q99623,P27105,O75477 5 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7663249917016802 2.0539743393309315 0.0399781753779207 1.0 0.0739188574952003 8 Q9HD20,P16615,P35670 3 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.8160500251344298 2.03612007038049 0.0417382998244963 1.0 0.0764260293369244 7 O95864,O15173,O00264,O43169 4 +Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120] 0.8058443382972718 2.026669105944906 0.0426962639873145 1.0 0.0774312833486419 2 Q8WVX9 1 +Fatty acyl-CoA reductase, C-terminal [IPR033640] 0.8058443382972718 2.026669105944906 0.0426962639873145 1.0 0.0774312833486419 2 Q8WVX9 1 +Ion transporter-like, CBS domain [IPR044751] 0.8033155380724845 2.0152072518536963 0.0438829380094256 1.0 0.0789281468947238 2 Q6P4Q7 1 +CNNM, transmembrane domain [IPR002550] 0.8033155380724845 2.0152072518536963 0.0438829380094256 1.0 0.0789281468947238 2 Q6P4Q7 1 +G-protein gamma-like domain [IPR015898] 0.7960101152008968 1.982034356182484 0.0474753955677951 1.0 0.0832284712423074 2 Q9UBI6 1 +GMP phosphodiesterase, delta subunit [IPR008015] 0.9030354131534588 1.9787041843310111 0.0478493215850075 1.0 0.0835744608249824 3 Q13432,O43924 2 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8751406074240583 1.9612057078848584 0.0498550313012557 1.0 0.0867117791586674 5 P27544,Q96G23,Q15629,Q96CP7 4 +Fzo/mitofusin HR2 domain [IPR006884] 0.7889856701320561 1.9500534869733368 0.0511697442948189 1.0 0.0881808700226248 2 O95140 1 +Intermediate filament, rod domain [IPR039008] 0.7354678288796248 1.912232335039977 0.0558464004114658 1.0 0.0935568668320283 8 P08670,P20700,Q03252,P07197,P02545,P07196 6 +Sterol-sensing domain [IPR000731] 0.8844856661045544 1.9049308556714264 0.0567890597121496 1.0 0.0944820911438224 3 O15118,Q12770 2 +Syntaxin, N-terminal domain [IPR006011] 0.8768971332209113 1.8746231536117808 0.0608445855688668 1.0 0.0996585061512916 3 O15400,Q12846 2 +Domain of unknown function DUF5600 [IPR040990] 0.7715650463613306 1.8703989764902025 0.0614284340056447 1.0 0.1004356664225856 2 Q9H223 1 +EH domain-containing protein, N-terminal [IPR031692] 0.7715650463613306 1.8703989764902025 0.0614284340056447 1.0 0.1004356664225856 2 Q9H223 1 +EF-hand domain [IPR002048] 0.4647395799985442 1.8685331104835896 0.0616877994207274 1.0 0.1005125360613114 50 Q8NF37,O75071,Q9BRK5,Q9H223,Q9Y680,Q9NWM8,Q6KCM7,P80303,O43852,O95202,Q9UBC2,Q6NUK1,Q14257,Q02818,Q9UJS0,P41208 16 +LEM domain [IPR003887] 0.8206464150816255 1.8313539315259564 0.0670477327075695 1.0 0.107187302994681 6 P42167,Q86XL3 2 +Lamin tail domain [IPR001322] 0.8552557616638574 1.7878036754896085 0.0738076876867197 1.0 0.1161295473851989 3 P20700,P02545 2 +Major facilitator superfamily domain [IPR020846] 0.8243668233652666 1.7562973155281365 0.0790376554180425 1.0 0.1233334842787037 5 Q5SR56,Q8NHS3,Q14728 3 +Phospholipid/glycerol acyltransferase [IPR002123] 0.8018825716000294 1.75377873970401 0.0794684273670967 1.0 0.1237337355935058 6 Q8NF37,Q9HCL2,Q92604 3 +Peptidase M41 [IPR000642] 0.7420623770722058 1.7344745171879288 0.0828339233935697 1.0 0.1272988866005076 2 Q96TA2 1 +Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520] 0.7395335768474173 1.7227692953979026 0.0849302533977214 1.0 0.1293917756925005 2 Q9HCL2 1 +GPAT/DHAPAT, acyltransferase domain [IPR041728] 0.7395335768474173 1.7227692953979026 0.0849302533977214 1.0 0.1293917756925005 2 Q9HCL2 1 +Legume-like lectin [IPR005052] 0.7372857544253932 1.7123580041050723 0.086830713331798 1.0 0.1311000669124436 2 P49257 1 +Bms1/Tsr1-type G domain [IPR030387] 0.7350379320033729 1.7019405784472132 0.0887665079551638 1.0 0.1327524394906083 2 Q14692 1 +AARP2CN [IPR012948] 0.7350379320033729 1.7019405784472132 0.0887665079551638 1.0 0.1327524394906083 2 Q14692 1 +Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034] 0.7350379320033729 1.7019405784472132 0.0887665079551638 1.0 0.1327524394906083 2 Q14692 1 +ABC transporter type 1, transmembrane domain [IPR011527] 0.6899291314635734 1.699306647527114 0.0892614207195645 1.0 0.1333521487867245 8 P28288,O14678,Q03518,P08183,Q03519 5 +Cadherin prodomain [IPR014868] 0.7305422871593077 1.681087816549387 0.0927458585253164 1.0 0.1374012718893577 2 Q14574 1 +Cadherin, cytoplasmic domain [IPR000233] 0.7305422871593077 1.681087816549387 0.0927458585253164 1.0 0.1374012718893577 2 Q14574 1 +Glycosyl transferase, family 1 [IPR001296] 0.8247533244151019 1.664545870607958 0.0960033922654435 1.0 0.1406135296719234 3 Q9BT22 1 +FF domain [IPR002713] 0.7055352627142464 1.564705037014723 0.1176520868904016 1.0 0.1646781304922329 2 O75400 1 +GINS subunit, domain A [IPR021151] 0.7964494794542564 1.5493859157508854 0.1212889774370302 1.0 0.1678532518074297 3 Q9Y248 1 +NECAP, PHear domain [IPR012466] 0.7004776622646807 1.5410982740450192 0.1232928698730828 1.0 0.1697144840001457 2 Q9NVZ3 1 +NAD-dependent epimerase/dehydratase [IPR001509] 0.794369234026632 1.5408972550933262 0.1233417940057397 1.0 0.1697144840001457 3 Q9NRG7 1 +Ribosomal protein L7, eukaryotic/archaeal [IPR035808] 0.6920483281820665 1.5017131247540818 0.1331712128295059 1.0 0.1785839053129223 2 P18124 1 +Ribosomal protein L30, ferredoxin-like fold domain [IPR016082] 0.6920483281820665 1.5017131247540818 0.1331712128295059 1.0 0.1785839053129223 2 P18124 1 +Ribosomal protein L30, N-terminal [IPR012988] 0.6920483281820665 1.5017131247540818 0.1331712128295059 1.0 0.1785839053129223 2 P18124 1 +Intermediate filament head, DNA-binding domain [IPR006821] 0.7883047511948177 1.5011777719037571 0.1333095875689416 1.0 0.1786580241856023 4 P07197,P08670,P07196 3 +Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333] 0.6906434391683047 1.495144569099666 0.1348767162871578 1.0 0.180004640157673 2 Q9UHQ9 1 +Zinc finger, CHHC-type [IPR012996] 0.7827431141090527 1.4934037859344766 0.1353315225489915 1.0 0.180442030065322 3 P31943,P55795 2 +ERAP1-like C-terminal domain [IPR024571] 0.785303589742665 1.4890644240505957 0.1364704048406093 1.0 0.1817046177905909 4 P55786,Q9NZ08 2 +Glycosyltransferase 2-like [IPR001173] 0.7553513085005445 1.4726119074602446 0.1408557121888587 1.0 0.1858876499146648 5 Q10472 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.7754356379988785 1.4635123801268313 0.1433272285523781 1.0 0.1883615590415334 3 P01889,P10321 2 +MHC class I, alpha chain, C-terminal [IPR010579] 0.7754356379988785 1.4635123801268313 0.1433272285523781 1.0 0.1883615590415334 3 P01889,P10321 2 +ABC transporter-like, ATP-binding domain [IPR003439] 0.5789724429845707 1.458201966320708 0.1447848819801573 1.0 0.1899256650455644 12 P28288,O14678,Q03518,P08183,Q03519 5 +Brix domain [IPR007109] 0.7517964404442338 1.457874502736945 0.1448751377710335 1.0 0.1899563209924909 5 Q8TDN6,Q9H7B2 2 +Ribosomal protein L10e/L16 [IPR016180] 0.6810901938746755 1.4504512439952295 0.1469327259698345 1.0 0.1924480814387133 2 P27635 1 +Immunoglobulin C1-set [IPR003597] 0.7756536407084518 1.450076305071161 0.1470372418778374 1.0 0.1924480814387133 4 P55899,P10321,P01889 3 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.6791233492554019 1.4412447040273346 0.1495155629877791 1.0 0.1946924341518994 2 O60506 1 +Target SNARE coiled-coil homology domain [IPR000727] 0.585780472277293 1.431644369600348 0.1522456246922208 1.0 0.1977939497373774 11 Q9UEU0,O60499,O15400,Q5SQN1,Q12846,Q86Y82 6 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.723329344426179 1.4240340934301343 0.1544366030441146 1.0 0.199454275873254 6 P09960 1 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.723329344426179 1.4240340934301343 0.1544366030441146 1.0 0.199454275873254 6 P09960 1 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.669228048177588 1.387556291706668 0.1652721987139438 1.0 0.2121939621824595 7 Q9H223,Q9H4M9,O95140,Q8IWA4,O60313 5 +Dynamin, N-terminal [IPR045063] 0.669228048177588 1.387556291706668 0.1652721987139438 1.0 0.2121939621824595 7 Q9H223,Q9H4M9,O95140,Q8IWA4,O60313 5 +Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.6653554369204768 1.3767694617118271 0.1685835352563998 1.0 0.2159572576130696 2 P20020 1 +LRRC8, pannexin-like TM region [IPR021040] 0.6639505479067105 1.3701887464581286 0.1706279902818943 1.0 0.2184776791706852 2 Q8TDW0 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.7556242023731381 1.3689992577643555 0.1709995069233092 1.0 0.2187561259739631 4 Q10472 1 +CARG-binding factor, N-terminal [IPR012956] 0.662826636695698 1.3649241309359517 0.1722768969839672 1.0 0.220291034414438 2 Q14103 1 +Ricin B, lectin domain [IPR000772] 0.7274558561996476 1.3567433083848943 0.174862786404145 1.0 0.2233964522662041 5 Q10472 1 +Chromo shadow domain [IPR008251] 0.7394603709949444 1.31607902719896 0.1881475194450907 1.0 0.2383313805638081 3 P83916,Q13185 2 +Chromo domain subgroup [IPR017984] 0.7394603709949444 1.31607902719896 0.1881475194450907 1.0 0.2383313805638081 3 P83916,Q13185 2 +GOLD domain [IPR009038] 0.6532526818018759 1.315224576528455 0.1884344377747255 1.0 0.2385884098440573 7 P49755,O76054,Q9Y3A6,Q15363 4 +NOPS [IPR012975] 0.7366005628386862 1.3043511760994633 0.1921138738903494 1.0 0.2425982222537093 3 Q8WXF1 1 +Alcohol dehydrogenase, N-terminal [IPR013154] 0.6945969668085372 1.3019510518106834 0.1929331189064145 1.0 0.2435244700863187 6 Q8N4Q0 1 +Homeobox domain [IPR001356] 0.7316829790722328 1.2841861809377426 0.1990768192440295 1.0 0.2500566858262025 3 Q96G23 1 +Ribosomal protein L18e/L15P [IPR021131] 0.7276559865092785 1.267675893206731 0.2049137170594202 1.0 0.2560294573025751 3 Q07020,P46776 2 +MABP domain [IPR023341] 0.6409103680809183 1.2623066205214477 0.2068384753323364 1.0 0.2580937038417583 2 Q96EY5 1 +Tripartite DENN domain [IPR037516] 0.6409103680809172 1.2623066205214415 0.2068384753323386 1.0 0.2580937038417583 2 A4D1U4 1 +Immunoglobulin-like domain [IPR007110] 0.4960680811273154 1.2517338365453992 0.2106668661836261 1.0 0.2622945637709331 17 P35613,P01889,O75962,P10586,Q08722,Q9Y639,P10321,Q9BY67,P55899 9 +Alpha/beta hydrolase fold-1 [IPR000073] 0.7254406488042214 1.2466215862926158 0.2125362828707171 1.0 0.2642745373698934 4 P07099 1 +SWIB domain [IPR019835] 0.6330429896038164 1.2255211742134866 0.2203789171357248 1.0 0.2735472572838543 2 Q92925 1 +EF-hand, Ca insensitive [IPR014837] 0.7155705452501444 1.2181540098437065 0.2231654526983859 1.0 0.2767641422110987 3 Q13813,P12814 2 +MHC class I-like antigen recognition-like [IPR011161] 0.6937238891755872 1.2162200915019696 0.223901092071806 1.0 0.2774341629511035 5 P01889,P10321 2 +Polyketide synthase, enoylreductase domain [IPR020843] 0.6304770075147514 1.2118341385933762 0.2255758774460947 1.0 0.2791440052056249 7 Q8N4Q0 1 +EB1, C-terminal [IPR004953] 0.6220848552964258 1.1743706901451787 0.2402465798772999 1.0 0.2957521832906509 2 Q15555 1 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.6774787829499068 1.1485529060187825 0.2507403855455088 1.0 0.3073382369224191 5 P05023,P16615 2 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.6774787829499068 1.1485529060187825 0.2507403855455088 1.0 0.3073382369224191 5 P05023,P16615 2 +Hemimethylated DNA-binding domain [IPR011722] 0.6139364990165714 1.136423860052581 0.2557792146523114 1.0 0.3121112521944881 2 Q9Y2S7 1 +SCP2 sterol-binding domain [IPR003033] 0.6593591905564972 0.9893505532789024 0.3224916580937644 1.0 0.3864456999942156 3 P51659,Q6YN16 2 +SLC12A transporter, C-terminal [IPR018491] 0.6517706576728548 0.9588102216704714 0.3376543588620602 1.0 0.4017337156130083 3 Q9BXP2,P55011 2 +Amino acid permease/ SLC12A domain [IPR004841] 0.6517706576728548 0.9588102216704714 0.3376543588620602 1.0 0.4017337156130083 3 Q9BXP2,P55011 2 +STAG [IPR013721] 0.5737566732228064 0.9511421420197398 0.3415322244276519 1.0 0.4058374549684233 2 Q8WVM7 1 +Stromalin conservative domain [IPR020839] 0.5737566732228064 0.9511421420197398 0.3415322244276519 1.0 0.4058374549684233 2 Q8WVM7 1 +GUCT [IPR012562] 0.5731947176172998 0.948580600738732 0.3428339613260793 1.0 0.4072139063848035 2 Q9NR30 1 +Cobalamin (vitamin B12)-binding domain [IPR006158] 0.5729137398145456 0.947300217208261 0.343485820192636 1.0 0.407647191536601 2 P22033 1 +AP complex, mu/sigma subunit [IPR022775] 0.567943906538162 0.9283927600680816 0.3532038726797082 1.0 0.4179579160043213 7 Q92572,Q96CW1,P61966,P53680 4 +Ariadne domain [IPR045840] 0.5670132059567208 0.9204739706594092 0.3573251291508641 1.0 0.4224826672724621 2 Q9Y4X5 1 +Longin domain [IPR010908] 0.6396852164137208 0.9104333734151832 0.3625940040768776 1.0 0.4272891998250341 3 O75396,P51809 2 +v-SNARE, coiled-coil homology domain [IPR042855] 0.6396852164137208 0.9104333734151832 0.3625940040768776 1.0 0.4272891998250341 3 O75396,P51809 2 +Ribosomal protein S4/S9, N-terminal [IPR001912] 0.5633604945209234 0.9039295026146924 0.3660327840930992 1.0 0.4308052659860761 2 Q9NV31 1 +S100/CaBP-9k-type, calcium binding, subdomain [IPR013787] 0.553807249227305 0.8609072427408992 0.389289132311744 1.0 0.4555340485230131 2 P31949 1 +ERM family, FERM domain C-lobe [IPR041789] 0.6225489465574123 0.8424989684383467 0.3995087168687756 1.0 0.4655743766546257 3 P35241 1 +COP9 signalosome complex subunit 7, helix I [IPR041481] 0.5476257375667215 0.8332791626739926 0.404687305320998 1.0 0.4708365207339756 2 Q9UBW8 1 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.5829112291780851 0.8289297536175394 0.4071441578726267 1.0 0.473307166745092 6 Q14141,Q16181,Q9NVA2,Q15019 4 +SANT domain [IPR017884] 0.4876755980332437 0.8223085444950244 0.4109013149551965 1.0 0.4774794330903266 9 Q96KC8 1 +Lens epithelium-derived growth factor, integrase-binding domain [IPR021567] 0.5439730261309246 0.817038210373605 0.4139065921430345 1.0 0.4804104450806111 2 Q7Z4V5 1 +SLIDE domain [IPR015195] 0.5428491149199125 0.812054291493915 0.4167604793773511 1.0 0.483101943441501 2 O60264 1 +ISWI, HAND domain [IPR015194] 0.5428491149199125 0.812054291493915 0.4167604793773511 1.0 0.483101943441501 2 O60264 1 +Dehydrogenase, E1 component [IPR001017] 0.6130578685685385 0.7971664475848457 0.4253543695221806 1.0 0.4912592149015831 4 P12694 1 +Vps16, C-terminal [IPR006925] 0.538634447878607 0.7934225672917581 0.4275316668309714 1.0 0.4919732308751859 2 Q9H9C1 1 +Far upstream element-binding protein, C-terminal [IPR015096] 0.5369485810620845 0.78599629574493 0.4318696572835907 1.0 0.495559525933494 2 Q92945 1 +GYF domain [IPR003169] 0.5318909806125198 0.7638123644515745 0.4449790674511824 1.0 0.5091621883808857 2 O95400 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.6014623612714838 0.7602347683623081 0.4471142658245139 1.0 0.5113993213619088 3 P13674 1 +Plectin/S10, N-terminal [IPR005326] 0.5304860915987585 0.7576762902016558 0.4486447963090547 1.0 0.512530660304793 2 P46783 1 +Metastasis-associated protein MTA1, R1 domain [IPR035170] 0.5288002247822311 0.7503285046918021 0.4530568790096221 1.0 0.5168157658083685 2 Q13330 1 +Alpha-D-phosphohexomutase, C-terminal [IPR005843] 0.5282382691767302 0.7478830572861855 0.4545306978703585 1.0 0.5177967035506691 2 Q96G03 1 +MCM N-terminal domain [IPR027925] 0.5627453744985192 0.7457145255163394 0.4558398827026106 1.0 0.5184562542552721 6 P33993,P33991 2 +MCM OB domain [IPR033762] 0.5627453744985192 0.7457145255163394 0.4558398827026106 1.0 0.5184562542552721 6 P33993,P33991 2 +MCM domain [IPR001208] 0.5627453744985192 0.7457145255163394 0.4558398827026106 1.0 0.5184562542552721 6 P33993,P33991 2 +MCM, AAA-lid domain [IPR041562] 0.5627453744985192 0.7457145255163394 0.4558398827026106 1.0 0.5184562542552721 6 P33993,P33991 2 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.4712055869255352 0.7402691775009222 0.459136679459132 1.0 0.5207460741469389 9 Q12959 1 +Guanylate kinase-like domain [IPR008144] 0.4712055869255352 0.7402691775009222 0.459136679459132 1.0 0.5207460741469389 9 Q12959 1 +Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717] 0.5254284911491873 0.7356850159583418 0.4619224106089701 1.0 0.5234874884794394 2 Q96HY7 1 +Arf GTPase activating protein [IPR001164] 0.5884036891745297 0.7101935369785675 0.4775841281647366 1.0 0.5380626212560796 3 Q15057 1 +FAD dependent oxidoreductase [IPR006076] 0.5875412497088437 0.6992497988186888 0.4843959339790364 1.0 0.5448255257427579 4 P43304,Q96CU9 2 +NET domain [IPR027353] 0.5158752458555744 0.6945948006612048 0.4873092715395755 1.0 0.5472354018079851 2 Q15059 1 +Brdt, bromodomain, repeat I [IPR043508] 0.5158752458555744 0.6945948006612048 0.4873092715395755 1.0 0.5472354018079851 2 Q15059 1 +Brdt, bromodomain, repeat II [IPR043509] 0.5158752458555744 0.6945948006612048 0.4873092715395755 1.0 0.5472354018079851 2 Q15059 1 +Pentacotripeptide-repeat region of PRORP [IPR033443] 0.5113796010115191 0.675476826231302 0.4993728696092543 1.0 0.5594552069784151 2 O75127 1 +tRNA-binding domain [IPR002547] 0.5096937341949869 0.6683458249534896 0.5039128683134197 1.0 0.5636520464789728 2 P54577 1 +4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.5786982853274956 0.6659601283134199 0.5054365859200483 1.0 0.5649114144088694 4 P21912 1 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.4397661949621326 0.6541683614501825 0.5130033426528611 1.0 0.5717933646523256 11 Q9NWM8 1 +CRAL-TRIO lipid binding domain [IPR001251] 0.533274610576024 0.626891776664967 0.5307301780407441 1.0 0.5897001978230489 6 O76054,P43378 2 +Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297] 0.4978926664793373 0.6190521758384813 0.5358819872557263 1.0 0.5942619460391498 2 Q9Y237 1 +Cadherin-like [IPR002126] 0.5609341717729915 0.6077545778620981 0.5433502590051087 1.0 0.6011354637999644 3 Q14574 1 +Thioredoxin domain [IPR013766] 0.3635932911506435 0.5869019315826759 0.5572695724472623 1.0 0.6143810503688761 24 P07237,Q9H3N1,O95881,Q9H1E5,Q9Y320,O43819 6 +GTPase effector domain [IPR020850] 0.4886203989884795 0.5811499906140933 0.5611393689988249 1.0 0.6172098404169879 2 P50570 1 +Dynamin GTPase effector [IPR003130] 0.4886203989884795 0.5811499906140933 0.5611393689988249 1.0 0.6172098404169879 2 P50570 1 +Dynamin stalk domain [IPR000375] 0.4886203989884795 0.5811499906140933 0.5611393689988249 1.0 0.6172098404169879 2 P50570 1 +Spen paralogue/orthologue C-terminal, metazoa [IPR010912] 0.4790671536948485 0.5429430595781581 0.5871690074648954 1.0 0.6413692235385781 2 Q96T37 1 +Glucosamine/galactosamine-6-phosphate isomerase [IPR006148] 0.4759763978645593 0.5307783950693912 0.5955723532630788 1.0 0.6500482256983642 2 O95336 1 +NOP5, N-terminal [IPR012974] 0.4756954200617994 0.5296774676447585 0.5963355730135693 1.0 0.6502976415051558 2 Q9Y2X3 1 +CBS domain [IPR000644] 0.4737330474936472 0.5192110764965736 0.6036135557094258 1.0 0.6563911575107987 7 P51790,Q6P4Q7,Q8NE01 3 +SUN domain [IPR012919] 0.5353402217867288 0.5165904765043383 0.6054420651599184 1.0 0.6575355506899304 3 Q9UH99 1 +Class I myosin, motor domain [IPR036072] 0.5297920179876403 0.4974743641289481 0.6188545765523825 1.0 0.6710756003851723 3 O94832,O00159 2 +Class I myosin tail homology domain [IPR010926] 0.5297920179876403 0.4974743641289481 0.6188545765523825 1.0 0.6710756003851723 3 O94832,O00159 2 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.5316277762159005 0.4961936931815068 0.6197577602536575 1.0 0.6717984882138882 4 P07900,P08238,Q12931 3 +ELM2 domain [IPR000949] 0.5289488476672358 0.4945912329493523 0.6208886919621277 1.0 0.672767602126075 3 Q9UKL0,Q13330 2 +Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468] 0.5269303119714956 0.4877131482732318 0.6257530372840798 1.0 0.677005190814014 3 A0FGR8 1 +CTP synthase, N-terminal [IPR017456] 0.4627704411351417 0.4799707077262689 0.6312482218911624 1.0 0.6816520723083275 2 Q9NRF8 1 +CTP synthase GATase domain [IPR033828] 0.4627704411351417 0.4799707077262689 0.6312482218911624 1.0 0.6816520723083275 2 Q9NRF8 1 +Synaptotagmin, SMP domain [IPR039010] 0.4565889294745659 0.456881998375414 0.6477558636486156 1.0 0.695511021838211 2 A0FGR8 1 +Extended synaptotagmin, C2B domain [IPR037749] 0.4565889294745659 0.456881998375414 0.6477558636486156 1.0 0.695511021838211 2 A0FGR8 1 +Extended synaptotagmin, C-terminal C2 domain [IPR037752] 0.4565889294745659 0.456881998375414 0.6477558636486156 1.0 0.695511021838211 2 A0FGR8 1 +Extended synaptotagmin, C2A domain [IPR037733] 0.4565889294745659 0.456881998375414 0.6477558636486156 1.0 0.695511021838211 2 A0FGR8 1 +Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678] 0.4557459960663083 0.4537697287049843 0.6499945735521189 1.0 0.6973874533011022 2 O95747 1 +Disulphide isomerase [IPR005788] 0.4997187851518663 0.4466536106450563 0.6551251809419101 1.0 0.7023614623914778 5 P07237,P13667,Q8NBS9,Q15084 4 +Ribosomal protein S7 domain [IPR023798] 0.4487215509974691 0.4281844310678236 0.6685168503546579 1.0 0.7150990037692009 2 Q9Y2R9 1 +RAD23A/RAD23B, UBA1 domain [IPR041811] 0.445068839561666 0.4151345019985649 0.6780434434270048 1.0 0.7236540320679045 2 P54727 1 +XPC-binding domain [IPR015360] 0.445068839561666 0.4151345019985649 0.6780434434270048 1.0 0.7236540320679045 2 P54727 1 +Ribosomal L28e/Mak16 [IPR029004] 0.4405731947176127 0.3993209292425212 0.6896567476425282 1.0 0.7346681032651088 2 P46779 1 +Immunoglobulin I-set [IPR013098] 0.4848787732504157 0.3957992583300972 0.6922531240050633 1.0 0.7371574323863441 5 P10586 1 +CCAAT-binding factor [IPR005612] 0.4971894322653249 0.3906481439626321 0.6960573339983902 1.0 0.7398214178725405 3 Q8WTT2,Q9BVI4 2 +Mu homology domain [IPR028565] 0.4780652418447801 0.3731517575376457 0.7090354990767032 1.0 0.7530519137538657 5 Q9Y2T2,Q96CW1,P48444,Q9H0R1 4 +Major sperm protein (MSP) domain [IPR000535] 0.4893198426082146 0.3664336569863182 0.7140415089201262 1.0 0.757801900348714 3 Q8NHP6,Q9P0L0 2 +Man1/Src1, C-terminal [IPR018996] 0.4279291935937043 0.3563828743773092 0.7215538528416392 1.0 0.7634921542735675 2 Q9Y2U8 1 +Glycosyl transferase CAP10 domain [IPR006598] 0.4822934232715063 0.3453845294037999 0.7298053061725285 1.0 0.7715331316372244 3 Q7Z4H8,Q8NBL1 2 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.4244974574130722 0.3287058322344788 0.7423780456032247 1.0 0.7802937266888077 7 Q8N543,P13674,O60568,Q32P28 4 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.4244974574130722 0.3287058322344788 0.7423780456032247 1.0 0.7802937266888077 7 Q8N543,P13674,O60568,Q32P28 4 +Nop domain [IPR002687] 0.4758291174817373 0.3265150380596753 0.7440347134855136 1.0 0.7814565777732466 3 Q8WWY3,Q9Y2X3 2 +NOSIC [IPR012976] 0.4758291174817373 0.3265150380596753 0.7440347134855136 1.0 0.7814565777732466 3 Q8WWY3,Q9Y2X3 2 +Cyclic nucleotide-binding domain [IPR000595] 0.4622414730201253 0.3224214804244908 0.7471334133545584 1.0 0.7844210328750262 5 Q6P4Q7 1 +Matrin/U1-C, C2H2-type zinc finger [IPR000690] 0.4485225555690615 0.3169379403187322 0.751290692717328 1.0 0.788203017110163 6 Q12874,Q15428 2 +Peptidase M16, C-terminal [IPR007863] 0.4184282534408038 0.3070398198461159 0.7588130632577696 1.0 0.7947965779653859 7 P22695,Q10713 2 +Peptidase M16, N-terminal [IPR011765] 0.4184282534408038 0.3070398198461159 0.7588130632577696 1.0 0.7947965779653859 7 P22695,Q10713 2 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.4679595278246261 0.3042098269014327 0.760968038633896 1.0 0.7956554632401885 3 Q5BKZ1,O43823 2 +RNA-binding S4 domain [IPR002942] 0.4617762788083275 0.2872155674278192 0.7739472671808008 1.0 0.8069053740064148 3 P46781,Q9NV31 2 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.4606520517144544 0.2841771450691384 0.776274629349589 1.0 0.8087380584566518 3 P61289,Q9UL46 2 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.4606520517144544 0.2841771450691384 0.776274629349589 1.0 0.8087380584566518 3 P61289,Q9UL46 2 +Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120] 0.4032031469513947 0.279553807950795 0.7798198504170284 1.0 0.8112411630711943 2 Q9Y305 1 +Laminin-type EGF domain [IPR002049] 0.4015172801348732 0.2746838246212529 0.7835591593978659 1.0 0.8142363749322866 2 P11047 1 +Laminin, N-terminal [IPR008211] 0.4015172801348732 0.2746838246212529 0.7835591593978659 1.0 0.8142363749322866 2 P11047 1 +Ribosomal protein S5, N-terminal [IPR013810] 0.401236302332115 0.2738769205448334 0.7841792084291745 1.0 0.8142848087527809 2 P82675 1 +Ribosomal protein S5, C-terminal [IPR005324] 0.401236302332115 0.2738769205448334 0.7841792084291745 1.0 0.8142848087527809 2 P82675 1 +Rpn11/EIF3F, C-terminal [IPR024969] 0.4579701996063983 0.2672959451125681 0.7892413085581769 1.0 0.8192417091758853 4 P51665,O00303,O00487 3 +ENTH domain [IPR013809] 0.4435056933476189 0.2398675160659132 0.81043296418513 1.0 0.8370418988533392 3 Q14677 1 +Ephrin receptor ligand binding domain [IPR001090] 0.3885923012082075 0.2390002494515617 0.8111053893114049 1.0 0.8370418988533392 2 Q15375 1 +Ephrin receptor, transmembrane domain [IPR027936] 0.3885923012082075 0.2390002494515617 0.8111053893114049 1.0 0.8370418988533392 2 Q15375 1 +Small-subunit processome, Utp12 [IPR007148] 0.4359190556492482 0.2215193617612723 0.8246880625380253 1.0 0.8498236928911436 3 Q15061,Q9UNX4 2 +Hyaluronan-mediated motility receptor, C-terminal [IPR031794] 0.3767912334925469 0.2090493143373218 0.8344097417116159 1.0 0.8595298028512837 2 O75330 1 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.4291736930860121 0.2058761925448538 0.8368876226751194 1.0 0.8617697057278242 3 Q9BYT8,Q99797 2 +KOW [IPR005824] 0.4087201125175825 0.1970074722614818 0.8438216903590061 1.0 0.8685949984123151 6 P61353,O00267,P61254,Q96A35,P62701 5 +JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.3541458009636124 0.1729400898727568 0.8626985192342524 1.0 0.8857786676157906 8 P51665,Q92905,O15372,O00487 4 +Histone-binding protein RBBP4, N-terminal [IPR022052] 0.3523461646529967 0.1552861295907591 0.8765957499560673 1.0 0.8980995418020313 2 Q16576 1 +PWI domain [IPR002483] 0.3953880764904418 0.1425870391398797 0.8866163341500286 1.0 0.9072410111214568 5 O43395,Q8IYB3,P49756,Q9P2N5 4 +BSD domain [IPR005607] 0.3979763912310344 0.1420197137781542 0.8870644341752576 1.0 0.9072410111214568 3 Q9NW68,Q96A49 2 +Immunoglobulin subtype 2 [IPR003598] 0.3212001502222625 0.1278197929937868 0.8982915860031446 1.0 0.9175424181176391 12 P35613,Q9BY67,P10586,Q9Y639 4 +Immunoglobulin subtype [IPR003599] 0.3212001502222625 0.1278197929937868 0.8982915860031446 1.0 0.9175424181176391 12 P35613,Q9BY67,P10586,Q9Y639 4 +EH domain [IPR000261] 0.3811963952303769 0.1271724932755656 0.8988038757758001 1.0 0.9175424181176391 6 Q9UBC2,Q9H223 2 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.3893730671914523 0.1131052607205833 0.9099471043070296 1.0 0.9275842700042942 4 Q9Y5X3,Q9UNH7,O60749 3 +Peripheral subunit-binding domain [IPR004167] 0.3721191680719568 0.0998924316479705 0.9204297249678228 1.0 0.9372608171059938 3 O00330,P11182 2 +SWIB/MDM2 domain [IPR003121] 0.3701517706576826 0.0970850732086317 0.9226588347144782 1.0 0.938857431239383 3 Q96GM5,Q92925 2 +2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078] 0.3722237840877133 0.0850375913516605 0.9322315053556424 1.0 0.9472134716647926 4 O00330,P36957,P11182 3 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.3605958403597603 0.0842321471886674 0.9328718592416988 1.0 0.9472134716647926 3 O60884,Q96EY1 2 +Chaperone DnaJ, C-terminal [IPR002939] 0.3609001406469826 0.083323874188809 0.9335940174426164 1.0 0.9476079376472588 6 Q9UBS4,O60884,Q9UDY4,Q96EY1,P25685 5 +FAST kinase-like protein, subdomain 2 [IPR013579] 0.2947457150885111 0.0721765498077823 0.9424614070334464 1.0 0.955583861469114 2 Q969Z0 1 +FAST kinase leucine-rich [IPR010622] 0.2947457150885111 0.0721765498077823 0.9424614070334464 1.0 0.955583861469114 2 Q969Z0 1 +RAP domain [IPR013584] 0.2947457150885111 0.0721765498077823 0.9424614070334464 1.0 0.955583861469114 2 Q969Z0 1 +Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.3535868995850079 0.0633730661220049 0.9494694342495582 1.0 0.9609740531962742 5 P10586 1 +Sterile alpha motif domain [IPR001660] 0.3028169014084541 0.0553906621697273 0.95582723492707 1.0 0.9667198529889168 11 P29317,Q9Y3Z3,Q6SPF0,Q6UWE0,Q96JM7,Q9UQR0,Q15375,Q13136,Q9Y6Y8,Q6SZW1 10 +Zinc finger, RanBP2-type [IPR001876] 0.3104163670204265 0.0494203769780913 0.960584289521671 1.0 0.9708396378083792 8 P35637,Q01844 2 +UAS [IPR006577] 0.3206857785272707 0.0437584264492781 0.9650969662072392 1.0 0.9750534984093062 3 Q96CS3,O94888 2 +Sec63 domain [IPR004179] 0.3063518830803906 0.0338753079496228 0.9729765832861604 1.0 0.9819664166782854 3 Q9UGP8,O75643 2 +YTH domain [IPR007275] 0.3025474081390538 0.0316110046556947 0.9747822673305098 1.0 0.9834393034524505 3 Q9BYJ9 1 +SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.3148720832161949 0.0207113634722909 0.9834759042250036 1.0 0.990133203257141 4 P46087,Q96P11,Q9H649 3 +Amine oxidase [IPR002937] 0.2793704328274384 0.0206697840896811 0.98350907267197 1.0 0.990133203257141 3 P50336,Q8NB78 2 +Copine, C-terminal [IPR010734] 0.270376616076455 0.0175785692986974 0.9859750532582984 1.0 0.9919125580069312 3 Q86YQ8,O75131 2 +Copine, C2B domain [IPR037768] 0.270376616076455 0.0175785692986974 0.9859750532582984 1.0 0.9919125580069312 3 Q86YQ8,O75131 2 +SWIRM domain [IPR007526] 0.2794489738543743 0.0001657395356493 0.9998677589839962 1.0 1.0 4 Q92922,Q8TAQ2,Q8NB78 3 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7be5aa97b5f0684e3e2ae69355a830675858e586 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3, EF hand domain [IPR039504]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "16S/18S rRNA aminocarboxypropyltransferase Tsr3, C-terminal [IPR007177]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-3' exoribonuclease 1, SH3-like domain [IPR041385]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "A-kinase anchor protein 10, PKA-binding (AKB) domain [IPR037719]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AF-9, ANC1 homology domain [IPR040930]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ASCH domain [IPR007374]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Activin types I and II receptor domain [IPR000472]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-amylase/branching enzyme, C-terminal all beta [IPR006048]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Atypical Protein Kinase C zeta, catalytic domain [IPR034662]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related protein 13, N-terminal [IPR018731]", "Autophagy-related, C-terminal [IPR015412]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BCAS3 domain [IPR022175]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BET1, SNARE domain [IPR039899]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRAP2, RNA recognition motif [IPR034932]", "BRCA1, serine-rich domain [IPR025994]", "BRCA1-associated 2 [IPR011422]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BRPF3, ePHD domain [IPR042005]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Bcr-Abl oncoprotein oligomerisation [IPR015123]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin/lipoyl attachment [IPR000089]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CKK domain [IPR014797]", "CLASP N-terminal domain [IPR024395]", "CLIP1, zinc knuckle [IPR032108]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRAL/TRIO, N-terminal domain [IPR011074]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "CYTH domain [IPR023577]", "Cactin, C-terminal [IPR019134]", "Cactin, central domain [IPR018816]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calmodulin-regulated spectrin-associated protein, CH domain [IPR022613]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cation/H+ exchanger [IPR006153]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centrosomal CEP44 domain [IPR029157]", "Centrosomal protein of 290kDa, coiled-coil region [IPR032321]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class IX myosin, motor domain [IPR036023]", "Class V myosin, motor domain [IPR036103]", "Class VI myosin, motor domain [IPR036114]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clp1, N-terminal beta-sandwich domain [IPR032324]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin II complex subunit H2, N-terminal [IPR009378]", "Condensin II complex subunit H2, middle domain [IPR031719]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Condensin-2 complex subunit H2, C-terminal [IPR031737]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Copper homeostasis CutC domain [IPR023648]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Cortactin-binding protein-2, N-terminal [IPR019131]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cupin-like domain 8 [IPR041667]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-A, N-terminal APC/C binding region [IPR032447]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEP domain [IPR000591]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIS3-like exonuclease 2, C-terminal [IPR041093]", "DIX domain [IPR001158]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA Ligase 4, adenylation domain [IPR044125]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 40, C-terminal [IPR015311]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase IV domain [IPR021536]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding protein SMUBP-2, R3H domain [IPR034072]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase III subunit RPC5, C-terminal [IPR045576]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding domain, Est1-type [IPR018834]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DTX3L, RING-HC finger [IPR042843]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Death effector domain [IPR001875]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deltex, C-terminal [IPR039396]", "Deoxycytidylate deaminase domain [IPR035105]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "DhaK domain [IPR004006]", "DhaL domain [IPR004007]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dienelactone hydrolase [IPR002925]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Dishevelled C-terminal [IPR024580]", "Dishevelled protein domain [IPR003351]", "Disks Large homologue 3, SH3 domain [IPR035763]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF1977, DnaJ-like [IPR015399]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4187 [IPR025239]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4378 [IPR025486]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF4976 [IPR032506]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Drought induced 19 protein type, zinc-binding domain [IPR008598]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERCC4 domain [IPR006166]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "EYA domain [IPR006545]", "EYA domain, metazoan [IPR042577]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "EngB-type guanine nucleotide-binding (G) domain [IPR030393]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 2, ligand binding domain [IPR034263]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease Xrn1, D2/D3 domain [IPR041106]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "F-box/LRR-repeat protein 18, LRR domain [IPR045627]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain [IPR002938]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM3C (ILEI) domain [IPR039475]", "FAM91, C-terminal domain [IPR028097]", "FAM91, N-terminal domain [IPR028091]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FCP1-like phosphatase, C-terminal [IPR015388]", "FCP1-like phosphatase, phosphatase domain [IPR011947]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FLYWCH-type zinc finger-containing protein, N-terminal [IPR029279]", "FYVE zinc finger [IPR000306]", "Fanconi anaemia group A protein, N-terminal domain [IPR031729]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "FeS cluster biogenesis [IPR000361]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein [IPR003382]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Focadhesin/RST, DUF3730 [IPR022542]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G2 and S phase-expressed protein 1, N-terminal [IPR032768]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCF, C-terminal [IPR022783]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GS domain [IPR003605]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galanin [IPR008174]", "Galanin message associated peptide (GMAP) [IPR013068]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-butyrobetaine hydroxylase-like, N-terminal [IPR010376]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gasdermin, PUB domain [IPR041263]", "Gasdermin, pore forming domain [IPR040460]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "Gid-type RING finger domain [IPR044063]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal [IPR006109]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal [IPR011128]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 13, N-terminal [IPR004193]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HBS1-like protein, N-terminal [IPR015033]", "HCLS1-binding protein 3, PX domain [IPR037901]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock factor (HSF)-type, DNA-binding [IPR000232]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Heavy metal-associated domain, HMA [IPR006121]", "Heavy metal-associated domain, copper ion-binding [IPR006122]", "Helical and beta-bridge domain [IPR010643]", "Helicase Helix-turn-helix domain [IPR029491]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISG20, DEDDh 3'-5' exonuclease domain [IPR037433]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KCTD15, tetramerisation-type BTB domain [IPR045904]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KIND domain [IPR011019]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-1 [IPR015143]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MABP domain [IPR023341]", "MAD homology 1, Dwarfin-type [IPR003619]", "MAD homology, MH1 [IPR013019]", "MAGE homology domain [IPR002190]", "MALT1 immunoglobulin-like domain [IPR041077]", "MALT1, death domain [IPR037940]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTMR14, PH-GRAM domain [IPR039803]", "MTMR6, PH-GRAM domain [IPR035998]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med12 [IPR019035]", "Mediator complex, subunit Med12, LCEWAV-domain [IPR021990]", "Mediator complex, subunit Med12, catenin-binding [IPR021989]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Mis18 domain [IPR034752]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial ABC-transporter, N-terminal five TM domain [IPR032410]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MnmG, N-terminal domain [IPR040131]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Muskelin, N-terminal [IPR010565]", "Mvd1, C-terminal [IPR041431]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin 5a, cargo-binding domain [IPR037988]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase intermediate-associated protein 30 [IPR013857]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NCBP2, RNA recognition motif [IPR034148]", "NDUFA6, LYR domain [IPR045299]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NEMO, Zinc finger [IPR034735]", "NET domain [IPR027353]", "NF-kappa-B essential modulator NEMO, CC2-LZ domain [IPR032419]", "NF-kappa-B essential modulator NEMO, N-terminal [IPR021063]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFRKB winged helix-like domain [IPR025220]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neogenin, C-terminal [IPR010560]", "Neurabin-1/2, PDZ domain [IPR040645]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Neuropilin, C-terminal [IPR022579]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Notch domain [IPR000800]", "Notch, C-terminal [IPR024600]", "Notch, NOD domain [IPR010660]", "Notch, NODP domain [IPR011656]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear hormone receptor, ligand-binding domain [IPR000536]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OST-HTH/LOTUS domain [IPR025605]", "OTU domain [IPR003323]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain [IPR019601]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Palmitoyltransferase, DHHC domain [IPR001594]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Par3/HAL, N-terminal [IPR021922]", "Patatin-like phospholipase domain [IPR002641]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, TIG domain 2 [IPR041362]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plexin-A1, Sema domain [IPR042744]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA cleavage complex subunit Clp1, C-terminal [IPR010655]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 3,4-dihydroxylase TPA1/OFD1, N-terminal domain [IPR039558]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein RMD5 homologue A, degenerated RING finger [IPR037680]", "Protein SirB1, N-terminal [IPR032698]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase C, PB1 domain [IPR034877]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative RNA-binding protein 47, RNA recognition motif 2 [IPR034440]", "Putative RNA-binding protein 47, RNA recognition motif 3 [IPR034445]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine 5'-phosphate oxidase, putative [IPR011576]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal [IPR019576]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAD51 interacting motif [IPR031419]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBB1NT [IPR012603]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RGS domain [IPR016137]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIO kinase [IPR000687]", "RIO2 kinase winged helix domain, N-terminal [IPR015285]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 2-O ribose methyltransferase, substrate binding [IPR013123]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Raptor, N-terminal CASPase-like domain [IPR029347]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "RecQ mediated genome instability protein, DUF1767 [IPR033472]", "RecQ mediated genome instability protein, N-terminal [IPR013894]", "Recq-mediated genome instability protein 1, C-terminal OB-fold domain [IPR032199]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Retinoblastoma-associated protein, A-box [IPR002720]", "Retinoblastoma-associated protein, B-box [IPR002719]", "Retinoblastoma-associated protein, C-terminal [IPR015030]", "Retinoblastoma-associated protein, N-terminal [IPR024599]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Riboflavin kinase domain, bacterial/eukaryotic [IPR015865]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "Ring finger protein 123, SPRY domain [IPR035773]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SAS-6 coiled-coil domain [IPR041513]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD2/Set2, SET domain [IPR044437]", "SETD7, SET domain [IPR044436]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SH3BP4, SH3 domain [IPR035456]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAD domain, Dwarfin-type [IPR001132]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMG1, PIKK catalytic domain [IPR039414]", "SMYD3, SET domain [IPR044420]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sde2, N-terminal ubiquitin domain [IPR024974]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase Rio2 [IPR030484]", "Serine/threonine-protein kinase SMG1, N-terminal [IPR035175]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Set2 Rpb1 interacting domain [IPR013257]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Signal transduction histidine kinase-related protein, C-terminal [IPR004358]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm8 [IPR034103]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "SoHo domain [IPR003127]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Sphingolipid delta4-desaturase, N-terminal [IPR013866]", "Spindle assembly abnormal protein 6, N-terminal [IPR032396]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulfotransferase domain [IPR000863]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Sushi/SCR/CCP domain [IPR000436]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Syndetin, C-terminal [IPR019514]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "Syntrophin, split Pleckstrin homology (PH) domain [IPR041428]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TDRD7, third LOTUS domain [IPR037978]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TFIIH p62 subunit, N-terminal [IPR013876]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THAP-type zinc finger [IPR006612]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TLDc domain [IPR006571]", "TNF receptor-associated factor 2, MATH domain [IPR037305]", "TNF receptor-associated factor, BIRC3 binding domain [IPR032070]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "TauD/TfdA-like domain [IPR003819]", "Telomerase activating protein Est1, N-terminal [IPR019458]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thg1 C-terminal domain [IPR025845]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine synthase, N-terminal [IPR029144]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription factor Tfb2, C-terminal domain [IPR040662]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tuberin, N-terminal [IPR024584]", "Tuberin-type domain [IPR018515]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glucuronate decarboxylase N-terminal [IPR021761]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UMA domain [IPR023340]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting protein 11, C-terminal [IPR024763]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar protein sorting-associated protein 54, N-terminal [IPR019515]", "Vacuolar protein sorting-associated, VPS28, C-terminal [IPR017899]", "Vacuolar protein sorting-associated, VPS28, N-terminal [IPR017898]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate heat shock transcription factor, C-terminal domain [IPR010542]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vesicle transport v-SNARE, N-terminal [IPR007705]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Vinexin, SH3 domain 1 [IPR035609]", "Vinexin, SH3 domain 2 [IPR035608]", "Vinexin, SH3 domain 3 [IPR035607]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WASP family, EVH1 domain [IPR033927]", "WD repeat protein mio, zinc-ribbon like domain [IPR031488]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WIBG, Mago-binding [IPR015362]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XIAP/BIRC8, UBA domain [IPR042579]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, D1 domain [IPR040992]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YegS/DAGK, C-terminal domain [IPR045540]", "Yip1 domain [IPR006977]", "Yippee/Mis18/Cereblon [IPR004910]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "ZZEF1, zinc finger, ZZ-type [IPR041986]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, AN1-type [IPR000058]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C2HC5-type [IPR009349]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FLYWCH-type [IPR007588]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, TRAF-type [IPR001293]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc finger, nuclear hormone receptor-type [IPR001628]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA capping enzyme, C-terminal [IPR013846]", "mRNA capping enzyme, adenylation domain [IPR001339]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, C-terminal [IPR026904]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNAHis guanylyltransferase catalytic domain [IPR024956]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTN1", "ACTN4", "ACVR1B", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP5M1", "APEH", "APEX1", "APIP", "APLP2", "APMAP", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARID4A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8B", "ARMCX3", "ARMT1", "ARSA", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATP7B", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCKDHA", "BCKDK", "BCOR", "BCR", "BCS1L", "BET1", "BIRC6", "BLM", "BLVRA", "BMS1", "BOP1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRIP1", "BRIX1", "BROX", "BRPF3", "BSDC1", "BSG", "BTF3", "BUB1B", "BZW1", "BZW2", "C1orf35", "C2CD5", "CACTIN", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CARM1", "CARS", "CASK", "CASP2", "CASP8", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CEP290", "CEP350", "CEP44", "CEP55", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLP1", "CLPB", "CLPX", "CLTC", "CLUH", "CMBL", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNPY2", "COA3", "COASY", "COG4", "COIL", "COLEC12", "COMMD2", "COMMD4", "COMMD7", "COMMD8", "COMMD9", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "CORO1C", "CORO7", "COTL1", "COX2", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CTTNBP2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTC", "CWC22", "CWC27", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DAGLB", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCK", "DCP1A", "DCP1B", "DCTD", "DCTN1", "DCUN1D1", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND4C", "DENR", "DEPDC1B", "DFFA", "DFFB", "DGCR8", "DHCR24", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC2H1", "EARS2", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC3", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAM129B", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FANCA", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBXL18", "FBXO21", "FBXO22", "FBXO7", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNBP4", "FNDC3A", "FOCAD", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GAL", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAN", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH11", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPRASP2", "GPS1", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2H1", "GTF2H4", "GTF3C1", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HS1BP3", "HSD17B4", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS14", "INTS3", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISG20L2", "ISOC1", "ISOC2", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2B", "ITPRIP", "ITSN2", "IVD", "IWS1", "JMJD6", "KARS", "KAT7", "KCMF1", "KCTD10", "KCTD12", "KCTD15", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIN", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LRSAM1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAK16", "MALT1", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED25", "MEPCE", "METAP1", "METAP2", "METTL13", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD8", "MGME1", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MINDY3", "MIOS", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MLLT1", "MMAB", "MMS19", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRM3", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL2", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVB12A", "MVD", "MVK", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "MYO9B", "NAA10", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH2", "NCBP1", "NCBP2", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "NDC80", "NDUFA10", "NDUFA2", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NEO1", "NES", "NF1", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN3", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUBP1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT21", "NUDT5", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OIP5", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLAA", "PLCD3", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R9B", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPN1", "PTPN11", "PTPN13", "PTPN9", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "RELA", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOK2", "RIOX2", "RIPK1", "RMI1", "RMND1", "RMND5A", "RNASEH2A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRP12", "RRP7A", "RSF1", "RTCA", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD1", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF11", "SCAP", "SCCPDH", "SCLY", "SCML2", "SCO2", "SCP2", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC14L2", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD7", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGSH", "SGTA", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC25A25", "SLC27A2", "SLC27A4", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG5", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNIP1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STRN3", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT1A4", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF6L", "TAGLN2", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D24", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX2", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THAP11", "THG1L", "THNSL1", "THOC1", "THOC2", "THOC3", "THOP1", "THTPA", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM10B", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TKFC", "TKT", "TLCD1", "TLE3", "TLK2", "TLN1", "TMCO6", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM104", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMLHE", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM56", "TRIO", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSR1", "TSR3", "TSTA3", "TTC4", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP32", "USP33", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS11", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS28", "VPS29", "VPS37B", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WASF2", "WASHC4", "WASL", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "WRN", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YBX1", "YBX3", "YES1", "YIPF4", "YKT6", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZDHHC20", "ZFAND1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZYX", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCD3", "ABCD4", "ACAP2", "ACOT9", "ACTN1", "AKAP8", "ALG1", "ANKLE2", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "AP5M1", "ARCN1", "ARFIP1", "ARIH1", "ATAD3A", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP7B", "BCKDHA", "BMS1", "BRD3", "BRIX1", "BSDC1", "BSG", "CADM1", "CALU", "CBX1", "CBX3", "CD2BP2", "CD47", "CERS1", "CERS2", "CETN2", "CLCN3", "CLINT1", "CNNM3", "CNNM4", "COPS5", "COPS7A", "CPNE3", "CPNE8", "CTPS2", "CYB5B", "CYB5R1", "DBT", "DDX21", "DHCR24", "DHTKD1", "DLG1", "DLST", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNM2", "DSC3", "EFCAB14", "EHD1", "EHD4", "EIF3F", "EIF3H", "EPHA2", "EPHA7", "EPHX1", "EPS15L1", "ERAP1", "ERGIC3", "ERLIN1", "ESYT2", "EWSR1", "FADS2", "FAF2", "FAR1", "FCGRT", "FKBP14", "FKBP7", "FLOT1", "FLOT2", "FOXRED1", "FUS", "GALNT1", "GINS2", "GM2A", "GNG12", "GPAM", "GPD2", "HDGFL2", "HLA-B", "HLA-C", "HMMR", "HNRNPD", "HNRNPH1", "HNRNPH2", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "IMP3", "KDELC2", "KDM1B", "KHSRP", "KIAA1147", "L3MBTL3", "LAMC1", "LEMD3", "LETM1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPCAT1", "LPGAT1", "LRRC8C", "LRSAM1", "LTA4H", "MAPRE2", "MCM4", "MCM7", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD8", "MIPEP", "MOSPD2", "MRPL24", "MRPS5", "MRPS7", "MTA1", "MTX1", "MUT", "MVB12A", "MYO1C", "MYO1D", "NCLN", "NECAP2", "NEFL", "NEFM", "NLN", "NOC3L", "NOC4L", "NOP2", "NOP58", "NPC1", "NPEPPS", "NPTN", "NSUN3", "NSUN5", "NUCB1", "NUCB2", "OGFOD1", "OPA1", "OXSR1", "P3H1", "P4HA1", "P4HB", "PDE6D", "PDHX", "PDIA4", "PDIA6", "PGLS", "PGM2", "PGRMC1", "PGRMC2", "PHB2", "PIN4", "PLD6", "PLOD3", "PMPCA", "POGLUT1", "POLDIP2", "PPFIA1", "PPOX", "PRPF3", "PRPF31", "PRPF40A", "PSMD14", "PSMD7", "PSME2", "PSME3", "PSPC1", "PTCD1", "PTPN9", "PTPRF", "RAD23B", "RBBP7", "RBM15", "RBM25", "RBM27", "RCN2", "RCOR1", "RDX", "RPF2", "RPL10", "RPL18", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL7", "RPL8", "RPS10", "RPS4X", "RPS9", "RTN3", "S100A11", "SAMD1", "SAMHD1", "SARM1", "SCAP", "SCML2", "SCO2", "SDF4", "SDHB", "SDR39U1", "SEC14L2", "SEC22B", "SEC23IP", "SEC63", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SF3A2", "SF3A3", "SLC12A2", "SLC12A9", "SLC25A13", "SLC25A24", "SLC25A25", "SLC38A2", "SMARCA5", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SNAP47", "SNRNP200", "SNX2", "SNX5", "SNX6", "SPTAN1", "SRRM1", "STAG1", "STARD3", "STARD3NL", "STOM", "STX10", "STX12", "STX4", "STX7", "SUN2", "SUPT5H", "SYAP1", "SYNCRIP", "TAP1", "TAP2", "TBRG4", "TIMM10B", "TIMM44", "TLCD1", "TMED10", "TMED2", "TMED5", "TMPO", "TMX1", "TMX2", "TMX4", "TRAM1", "TRAP1", "TRIO", "TXNDC12", "TXNDC5", "UBXN7", "UNC119", "UQCRC2", "VAMP7", "VAPA", "VIM", "VIPAS39", "VTI1B", "WDR3", "WDR43", "YARS", "YME1L1", "YTHDF1", "ZADH2", "ZDHHC13", "ZNF326"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6bc77b3f5c84d1db75e9b908ed2b0fcaab0b6f4d --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..813d1e2457cf4cc44236ddf6f473deb13ed1d82d --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1d204e92298bc27eb5335b575a4caba8f8f9f8c5480031be42efd4cbcf6f4709 +size 188941 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..de6664e5e24b15e2de0299a264ca8a69ff506c8c --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Short-chain dehydrogenase/reductase SDR [IPR002347]", "2": "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "3": "Sec1-like protein [IPR001619]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ec13234b531bf5061db6092304c69acba78cb2a7 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e9dc64e2a6012f3044f5f7048db2fd9c154e995eabb5a1aab34e82df54a1e131 +size 142433 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..4478cfcdd24c602104b7e29e5be995cc594c35ca --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:33955eaaef61dc7e3c2fbbbf82d896cd1b27b6bd8844849f56c843dded600ac7 +size 147424 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..86680b54ae005d716fb05f4075f2dd0cb3de347b --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dde947526f2ca5196c5e3d5c24f40ddad1f65a38dac2cf7e2f4b1509b01d1163 +size 140928 diff --git a/interpro_family/basic/plot_3.png b/interpro_family/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..a3ca65259ed3e382df402e51598731473968a606 --- /dev/null +++ b/interpro_family/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c09d37ffc3d4dff7b494a15fd680847b7d79e82f3be3e499f6090d22952f722f +size 134198 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..51ce10d8f69237b4e1c0398bf503aee6467eb495 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bb49fba6462cc84d2b7c30480bb00e30c527f39e4e0c33b103db7b38c1915914 +size 936857 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2e8b7646ba9537e2d9af1c6874c9ac75fa27999b --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier protein [IPR002067] 10 13 2.7234826823025435 0.0064597602187441 5.686893203883495 11.07766990291262 0.8032246115450145 0.31892620527414 3.2338505495684404 1.5403272908315857 1.3918146051602212 0.3274613788058813 0.0046437067491223 1.0 1.0 0.0011116174795585 7.180176827125465e-09 +P-type ATPase [IPR001757] 3 8 2.0539743393309315 0.0399781753779207 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0546082347726425 1.0 1.0 0.0145721558996701 0.0193421266882966 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c01fad7307b3076e2f60b7f8f03daf286f6a9554 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 2737, + "title": "Average number of proteins per term", + "value": 1.289002557544757 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d0cf3ff36ea16f787f6ae0e5f6b0476433a82fd6 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1f1d961faa9380afe52920b22521193cfcb8da7d --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,151 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9983141331834784 2.8639958422124057 0.0041833350263429 0.9999896010333614 0.0090564664965803 2 O60830 1 +Cytochrome P450 [IPR001128] 0.9935375105366676 2.8440793646553972 0.0044539952120445 0.999995058364366 0.0095329560656302 2 Q16850 1 +CD36 family [IPR002159] 0.992413599325653 2.839386769404569 0.0045200333744936 0.9999958788376044 0.0096425029976533 2 Q14108 1 +Haem oxygenase-like [IPR016053] 0.9820174206237696 2.795865051999782 0.0051761008437225 0.9999993217703588 0.0108062456211049 2 P30519 1 +Haem oxygenase [IPR002051] 0.9820174206237696 2.795865051999782 0.0051761008437225 0.9999993217703588 0.0108062456211049 2 P30519 1 +Nucleobindin [IPR040250] 0.9786456869907274 2.7817051579474055 0.005407414120877 0.9999996411108976 0.0111362621887438 2 Q02818 1 +Mpv17/PMP22 [IPR007248] 0.9727451531329014 2.756872487667725 0.0058357103638977 0.9999998895967596 0.0118841810014792 2 Q567V2 1 +Mitochondrial carrier UCP-like [IPR002030] 0.9679685304860914 2.7367205048553083 0.0062054990993674 0.9999999601191096 0.0124155343822869 2 Q9H2D1 1 +Mitochondrial carrier protein [IPR002067] 0.8076368951455413 2.7234826823025435 0.0064597602187441 0.9999999802026212 0.012793316728439 13 P05141,O43808,Q9HC21,Q86VD7,Q6KCM7,P12236,Q8TBP6,Q6NUK1,Q9UJS0,P12235 10 +Tetraspanin/Peripherin [IPR018499] 0.9634728856420324 2.7177135418341054 0.0065734722105679 0.999999985527094 0.012915457444274 2 O60637 1 +Tetraspanin, animals [IPR000301] 0.9634728856420324 2.7177135418341054 0.0065734722105679 0.999999985527094 0.012915457444274 2 O60637 1 +Yif1 family [IPR005578] 0.9553245293621794 2.6831634447706905 0.0072929338340721 0.9999999980075523 0.0140866336653884 2 O95070 1 +Palmitoyl protein thioesterase [IPR002472] 0.9544815959539176 2.6795819348845473 0.0073714160422029 0.9999999983952444 0.0141844829284155 2 P50897 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.9542006181511656 2.6783877913231806 0.0073977514302634 0.9999999985076452 0.0141989100032475 2 Q96KA5 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.9542006181511656 2.6783877913231806 0.0073977514302634 0.9999999985076452 0.0141989100032475 2 Q96KA5 1 +Protein-tyrosine phosphatase-like, PTPLA [IPR007482] 0.9409946614217471 2.622089806639192 0.008739239880606 0.9999999999631598 0.0163271669305248 2 Q9P035 1 +Lysosome-associated membrane glycoprotein [IPR002000] 0.9185164372014608 2.5254825415870568 0.0115539522067251 0.9999999999999848 0.0204548300063433 2 P13473 1 +Sulfotransferase [IPR005331] 0.8988479910087066 2.4401449154528967 0.0146813711664868 1.0 0.0247584182887704 2 Q8NCH0 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8811463894352316 2.362700849670908 0.0181423076444002 1.0 0.029347219871586 2 Q9NVI7 1 +Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439] 0.874402922169143 2.3330398984937113 0.0196460513581364 1.0 0.0314451710919412 2 Q96G23 1 +SUN domain-containing protein 1-5 [IPR045119] 0.8729980331553782 2.3268495901201356 0.0199732719855902 1.0 0.031826498436511 2 Q9UH99 1 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.8685023883113154 2.307015325535075 0.0210539657568276 1.0 0.0332898349372831 2 Q9Y282 1 +Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129] 0.8645686990727705 2.28962883303116 0.0220428420922962 1.0 0.0345539855707988 2 Q99735 1 +Integral membrane protein EMC3/TMCO1-like [IPR002809] 0.8564203427929139 2.253520872165841 0.0242263262118571 1.0 0.0373142683409415 2 Q9UM00 1 +Derlin [IPR007599] 0.856139364990158 2.252273539933426 0.0243049912124 1.0 0.037414376236411 2 Q9BUN8 1 +Peptidase A22B, signal peptide peptidase [IPR007369] 0.8516437201461017 2.2322960992837793 0.025595399522261 1.0 0.0390493915788342 2 Q8TCT8 1 +Presenilin/signal peptide peptidase [IPR006639] 0.8516437201461017 2.2322960992837793 0.025595399522261 1.0 0.0390493915788342 2 Q8TCT8 1 +ABC transporter Tap-like [IPR013305] 0.8502388311323394 2.2260453989828535 0.026011140650751 1.0 0.0395953792887128 2 Q03519 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.964586846543002 2.2201048648594224 0.0264116500563218 1.0 0.0401603812245293 3 Q9NPR9,Q5VW38 2 +TAF15/EWS/TLS family [IPR034870] 0.8485529643158176 2.2185397020896604 0.0265180556824728 1.0 0.0402550850820456 2 P35637 1 +Arfaptin family [IPR030798] 0.8426524304579905 2.1922282025412136 0.0283630330161182 1.0 0.0423973901502542 2 P53367 1 +Small GTPase superfamily, SAR1-type [IPR006687] 0.8420904748524826 2.1897189860756474 0.0285446232737169 1.0 0.0425791118897533 2 Q9NR31 1 +Ribosomal protein L2 [IPR002171] 0.8353470075864009 2.159563107726897 0.030806506982967 1.0 0.0453319406518176 2 P62917 1 +Disks large 1-like [IPR016313] 0.8330991851643659 2.1494926631549696 0.0315953670616551 1.0 0.0463184358049009 2 Q12959 1 +Copper chaperone SCO1/SenC [IPR003782] 0.8308513627423432 2.13941303250895 0.0324022323875023 1.0 0.0471979297735998 2 O75880 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.8308513627423432 2.13941303250895 0.0324022323875023 1.0 0.0471979297735998 2 O75880 1 +Porin, eukaryotic type [IPR001925] 0.9435075885328844 2.1380409808045515 0.0325134173136278 1.0 0.0473003279881065 3 P45880,P21796 2 +Oligosaccharyl transferase, STT3 subunit [IPR003674] 0.8246698510817572 2.111646978730613 0.0347167399060257 1.0 0.0497225102683372 2 P46977 1 +Basigin-like [IPR043204] 0.8243888732790028 2.110383253857349 0.0348253577120964 1.0 0.0498519895700879 2 P35613 1 +Flotillin family [IPR027705] 0.817083450407409 2.0774770603068875 0.0377575503316998 1.0 0.0531870382181484 2 O75955 1 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.9277684092186628 2.076348891847288 0.0378616944645537 1.0 0.0531968468939854 3 Q9H3G5,Q9HB40 2 +Stomatin/HflK/HflC family [IPR001972] 0.8165214948019006 2.0749419005411287 0.0379919197470564 1.0 0.0532597190604895 2 P27105 1 +THRAP3/BCLAF1 family [IPR029199] 0.8162405169991571 2.073674112210743 0.038109587053456 1.0 0.053380726594324 2 Q9Y2W1 1 +Protein Yip1/4-like [IPR045231] 0.8123068277606061 2.0559105372485846 0.039791140253335 1.0 0.0552834268392782 2 Q9BSR8 1 +Torsin-1A-interacting protein 1/2 [IPR008662] 0.8120258499578473 2.0546406756400506 0.0399137238425988 1.0 0.0553974960229173 2 Q5JTV8 1 +P-type ATPase [IPR001757] 0.7663249917016802 2.0539743393309315 0.0399781753779207 1.0 0.0554393935151054 8 Q9HD20,P16615,P35670 3 +Ergosterol biosynthesis ERG4/ERG24 [IPR001171] 0.9210230466554256 2.049802261347771 0.04038373085878 1.0 0.0558233693739802 3 O76062,Q14739 2 +Ribosomal protein L13 [IPR005822] 0.8064062939027739 2.0292146985862543 0.0424364271006627 1.0 0.0581906317507585 2 Q9BYD1 1 +Fatty acyl-CoA reductase [IPR026055] 0.8058443382972718 2.026669105944906 0.0426962639873145 1.0 0.0584298372666399 2 Q8WVX9 1 +TB2/DP1/HVA22-related protein [IPR004345] 0.8050014048890073 2.0228497022261944 0.0430886455749002 1.0 0.0588784937286579 2 Q00765 1 +Ancient conserved domain protein family [IPR045095] 0.8033155380724845 2.0152072518536963 0.0438829380094256 1.0 0.0596956269044721 2 Q6P4Q7 1 +Chloride channel, voltage gated [IPR001807] 0.8021916268614736 2.0101095955163255 0.0444195907162221 1.0 0.0603356922036228 2 P51790 1 +Eukaryotic porin/Tom40 [IPR027246] 0.9156592634242284 2.006960016850448 0.0447539204836975 1.0 0.0606393467147921 4 P45880,Q9Y277,P21796 3 +G-protein, gamma subunit [IPR001770] 0.7960101152008968 1.982034356182484 0.0474753955677951 1.0 0.063821295515253 2 Q9UBI6 1 +Mitofusin family [IPR027094] 0.7889856701320561 1.9500534869733368 0.0511697442948189 1.0 0.0679202667967601 2 O95140 1 +Prenylated rab acceptor PRA1 [IPR004895] 0.7811182916549515 1.9141396985137284 0.0556023082486532 1.0 0.0727710812964093 2 O75915 1 +Graves disease carrier protein [IPR002167] 0.8858909499718957 1.9105353926775877 0.0560643138969518 1.0 0.0731230350104928 3 Q86VD7,Q6KCM7 2 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.7788704692329207 1.9038605241052011 0.0569283515180056 1.0 0.0740907741820169 2 Q93050 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.7788704692329207 1.9038605241052011 0.0569283515180056 1.0 0.0740907741820169 2 Q93050 1 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.883361439010681 1.900445413702009 0.0573746919947315 1.0 0.074494559767353 3 P12236,P12235 2 +Nonaspanin (TM9SF) [IPR004240] 0.8825182686902773 1.8970802786875656 0.0578173436227884 1.0 0.0748916561739574 3 Q9HD45,Q99805 2 +Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434] 0.7712840685585749 1.86911036121886 0.0616074617959592 1.0 0.0789787461056395 2 Q969T7 1 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.8717487017531903 1.8540200583773363 0.0637362903756506 1.0 0.0812511535901983 3 Q9NPH0 1 +Torsin [IPR010448] 0.7631357122787227 1.8316892010612735 0.0669977384662172 1.0 0.0845035991622288 2 O14656 1 +Torsin 1/2 [IPR017378] 0.7631357122787227 1.8316892010612735 0.0669977384662172 1.0 0.0845035991622288 2 O14656 1 +UBAP2/protein lingerer [IPR022166] 0.7600449564484313 1.8174695202429572 0.0691452512463977 1.0 0.0867326089190607 2 Q5T6F2 1 +YTH domain containing protein [IPR045168] 0.7575161562236572 1.805825083472827 0.0709456660819516 1.0 0.0884639125586795 2 Q9BYJ9 1 +Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309] 0.755549311604373 1.796762074856476 0.0723733995394653 1.0 0.0899164750519821 2 O95478 1 +Major facilitator superfamily [IPR011701] 0.8243668233652666 1.7562973155281365 0.0790376554180425 1.0 0.0967036490295853 5 Q5SR56,Q8NHS3,Q14728 3 +Peptidase, FtsH [IPR005936] 0.7420623770722058 1.7344745171879288 0.0828339233935697 1.0 0.100628694331203 2 Q96TA2 1 +Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284] 0.7395335768474173 1.7227692953979026 0.0849302533977214 1.0 0.1027194447854898 2 Q9HCL2 1 +Ribosome biogenesis protein Bms1/Tsr1 [IPR039761] 0.7350379320033729 1.7019405784472132 0.0887665079551638 1.0 0.1064187175967075 2 Q14692 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.8356319943026382 1.6912263966614496 0.0907935713275116 1.0 0.1084214680294063 4 Q01105,Q99733 2 +Prohibitin [IPR000163] 0.7302613093565491 1.6797837434945382 0.0929993992185633 1.0 0.1106692850700904 2 Q99623 1 +Ribosomal protein L15 [IPR030878] 0.7274515313290173 1.6667381209521088 0.0955664892563705 1.0 0.1130849464309062 2 P46776 1 +Synaptobrevin [IPR001388] 0.7235178420904761 1.6484596731014889 0.0992583794568988 1.0 0.1165966457397133 2 P51809 1 +Syntaxin [IPR045242] 0.775198352876495 1.642599549599159 0.1004658140270768 1.0 0.1177118720000468 6 Q86Y82,O60499,O15400,Q12846 4 +Ras GTPase-activating protein-binding protein [IPR039539] 0.6976678842371447 1.5279751883270378 0.1265186984067092 1.0 0.1430324979509142 2 Q9UN86 1 +Tricarboxylate/iron carrier [IPR004686] 0.7903316469926948 1.5244130963447484 0.1274055506221971 1.0 0.1437975224960633 3 Q96NB2,Q6P4A7 2 +Ribosomal protein L7/L30 [IPR039699] 0.6920483281820665 1.5017131247540818 0.1331712128295059 1.0 0.1490145582642509 2 P18124 1 +Ribosomal protein L7, eukaryotic [IPR005998] 0.6920483281820665 1.5017131247540818 0.1331712128295059 1.0 0.1490145582642509 2 P18124 1 +Sodium/potassium-transporting ATPase subunit beta [IPR000402] 0.6917673503793189 1.500399505571516 0.1335109475395448 1.0 0.1493194945665823 2 P05026 1 +NADH:cytochrome b5 reductase-like [IPR001834] 0.6906434391683047 1.495144569099666 0.1348767162871578 1.0 0.1504922839290464 2 Q9UHQ9 1 +Aminopeptidase N-type [IPR034016] 0.785303589742665 1.4890644240505957 0.1364704048406093 1.0 0.1519607396455442 4 P55786,Q9NZ08 2 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.723329344426179 1.4240340934301343 0.1544366030441146 1.0 0.1690095891770259 6 P09960 1 +E3 ubiquitin ligase Bre1 [IPR013956] 0.6681652149480166 1.3899304716453689 0.1645499914670576 1.0 0.179718007440278 2 Q5VTR2 1 +P-type ATPase, subfamily IIB [IPR006408] 0.6653554369204768 1.3767694617118271 0.1685835352563998 1.0 0.1840499146377208 2 P20020 1 +Sorting nexin-5/6/32 [IPR014637] 0.653835347007583 1.3228099439645995 0.1858985894938079 1.0 0.2018264337344514 2 Q9UNH7 1 +Calreticulin/calnexin [IPR001580] 0.7315688738063812 1.2837183194259447 0.1992405321466654 1.0 0.2157125539894871 3 P27824 1 +Short-chain dehydrogenase/reductase SDR [IPR002347] 0.4831367983620198 1.2787629354002852 0.2009805496952301 1.0 0.2174244128521126 19 Q96LJ7,Q3SXM5,Q53GQ0,Q6IAN0,Q06136 5 +Microtubule-associated protein RP/EB [IPR027328] 0.6220848552964258 1.1743706901451787 0.2402465798772999 1.0 0.258472833775224 2 Q15555 1 +Bcl2-like [IPR002475] 0.7046021784485408 1.1732670920745938 0.2406887144796918 1.0 0.2587450948668172 3 Q9BXK5 1 +Bcl-2 family [IPR026298] 0.7046021784485408 1.1732670920745938 0.2406887144796918 1.0 0.2587450948668172 3 Q9BXK5 1 +Type 1 protein exporter [IPR039421] 0.679602424661802 1.1573938654502824 0.2471114792401674 1.0 0.2654411768761139 5 P08183,Q03519 2 +Adaptor protein complex, sigma subunit [IPR016635] 0.6596577792351123 0.9811649221339108 0.326511419216227 1.0 0.3470531085028401 4 Q92572,P61966 2 +Twinfilin [IPR028458] 0.5765664512503423 0.9639650302805766 0.3350634584375258 1.0 0.3560049245898712 2 Q6IBS0 1 +SCAMP [IPR007273] 0.6548450266197443 0.9619371286026392 0.3360811865948792 1.0 0.3569476941056206 4 O15127,O15126 2 +SLC12A transporter family [IPR004842] 0.6517706576728548 0.9588102216704714 0.3376543588620602 1.0 0.3584794337492081 3 Q9BXP2,P55011 2 +Cohesin subunit Scc3/SA [IPR039662] 0.5737566732228064 0.9511421420197398 0.3415322244276519 1.0 0.3621750090114232 2 Q8WVM7 1 +Paraneoplastic antigen Ma [IPR026523] 0.5703849395897632 0.9357885908441806 0.349382046876131 1.0 0.370355794848943 2 Q9H0W5 1 +Ribosomal protein S4/S9 [IPR022801] 0.5633604945209234 0.9039295026146924 0.3660327840930992 1.0 0.3868076177848698 2 Q9NV31 1 +Transmembrane emp24 domain-containing protein [IPR015720] 0.6151550864349064 0.8910254524395281 0.3729155157442405 1.0 0.393473310174243 5 P49755,Q9Y3A6,Q15363 3 +Ezrin/radixin/moesin [IPR011174] 0.6225489465574123 0.8424989684383467 0.3995087168687756 1.0 0.4203980615416528 3 P35241 1 +Septin [IPR016491] 0.5829112291780851 0.8289297536175394 0.4071441578726267 1.0 0.4279391551833253 6 Q14141,Q16181,Q9NVA2,Q15019 4 +Tyrosine-tRNA ligase [IPR002307] 0.5417252037088959 0.8070767943193422 0.4196222407413419 1.0 0.4405470168427514 2 Q9Y2Z4 1 +Vacuolar protein sorting-associated protein 33 [IPR027121] 0.5383534700758593 0.7921837868044723 0.4282535208159055 1.0 0.4489199105603728 2 Q96AX1 1 +Small GTPase superfamily, ARF/SAR type [IPR006689] 0.4797815671558293 0.7828717470585759 0.4337024300193342 1.0 0.4537628252916352 9 Q8N8L6,Q9NR31 2 +Mesoderm induction early response protein/metastasis-associated protein [IPR040138] 0.5288002247822311 0.7503285046918021 0.4530568790096221 1.0 0.4732888083394411 2 Q13330 1 +Mini-chromosome maintenance protein [IPR031327] 0.5627453744985192 0.7457145255163394 0.4558398827026106 1.0 0.4760144063170719 6 P33993,P33991 2 +2-oxoglutarate dehydrogenase E1 component [IPR011603] 0.5254284911491873 0.7356850159583418 0.4619224106089701 1.0 0.4816311001282862 2 Q96HY7 1 +Tight junction protein ZO [IPR005417] 0.5186850238831051 0.7066163875747943 0.4798049022313526 1.0 0.4997054860758037 2 Q07157 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666] 0.5832669199318 0.6831128496552035 0.4945355364249311 1.0 0.5144598111725718 4 Q9Y3C6 1 +Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237] 0.5755004723111643 0.6615549539775296 0.508256484708635 1.0 0.5279309292780016 3 Q9UBW8 1 +Calcium uptake protein 1/2/3 [IPR039800] 0.5066029783647085 0.6553283549364318 0.5122563685040702 1.0 0.5318837938526707 2 Q8IYU8 1 +Ribosomal protein S11 [IPR001971] 0.49648777746557 0.6132604408836035 0.5397041459859362 1.0 0.5586876881858953 2 P82912 1 +Vesicle-associated membrane-protein-associated protein [IPR016763] 0.4891823545939796 0.5834248724565115 0.5596073181038479 1.0 0.5773257556163708 2 Q9P0L0 1 +Enoyl-CoA hydratase/isomerase [IPR001753] 0.5168714358233603 0.5626488491249826 0.5736740215005831 1.0 0.5913920138783789 6 P40939 1 +Nucleolar protein Nop56/Nop58 [IPR045056] 0.4756954200617994 0.5296774676447585 0.5963355730135693 1.0 0.6140596175087055 2 Q9Y2X3 1 +Target of Myb protein 1 [IPR014645] 0.4695139084012369 0.5056718348897544 0.6130870435820266 1.0 0.630123634353739 2 O60784 1 +Heat shock protein Hsp90 family [IPR001404] 0.5316277762159005 0.4961936931815068 0.6197577602536575 1.0 0.6367406117921398 4 P07900,P08238,Q12931 3 +Actin-related protein 2/3 complex subunit 1 [IPR017383] 0.4638943523461522 0.4842177629791953 0.6282313318722959 1.0 0.6452041858665942 2 Q92747 1 +CTP synthase [IPR004468] 0.4627704411351417 0.4799707077262689 0.6312482218911624 1.0 0.6478164166914553 2 Q9NRF8 1 +Peptidyl-tRNA hydrolase, PTH2 [IPR002833] 0.4518123068277594 0.4393639647659078 0.6603978328448226 1.0 0.6762098273461576 2 Q9Y3E5 1 +Ribosomal protein S5/S7 [IPR000235] 0.4487215509974691 0.4281844310678236 0.6685168503546579 1.0 0.6842672473525425 2 Q9Y2R9 1 +UV excision repair protein Rad23 [IPR004806] 0.445068839561666 0.4151345019985649 0.6780434434270048 1.0 0.6934995906800121 2 P54727 1 +Ribosomal protein L14P [IPR000218] 0.4318628828322557 0.3694912137353941 0.711761621002845 1.0 0.7260870505720413 2 Q6P1L8 1 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.4635724331927 0.3673026252616968 0.713393296065876 1.0 0.7274804215097997 6 P04899,P63096,P29992,Q14344,P09471 5 +YEATS [IPR005033] 0.4301770160157332 0.363845079510003 0.7159736978371372 1.0 0.7298398551136851 2 O95619 1 +Glutathione Transferase family [IPR040079] 0.3853024474709682 0.3600678804160041 0.7187963717694086 1.0 0.7321718159779945 10 Q9H7Z7,Q8TB36,Q13505 3 +Clathrin adaptor, mu subunit [IPR001392] 0.4777965148960158 0.3322065616180217 0.7397332894075173 1.0 0.7518195369878852 3 Q9Y2T2,Q96CW1 2 +Luc7-related [IPR004882] 0.4172520370890629 0.3219972030113059 0.7474548134429597 1.0 0.7593852354838088 2 Q9Y383 1 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.4679595278246261 0.3042098269014327 0.760968038633896 1.0 0.7722541793626152 3 Q5BKZ1,O43823 2 +Proteasome activator PA28 [IPR009077] 0.4606520517144544 0.2841771450691384 0.776274629349589 1.0 0.7872040239087904 3 P61289,Q9UL46 2 +G-protein alpha subunit, group I [IPR001408] 0.463311779589546 0.2819372769722866 0.7779916055857701 1.0 0.7886529720326861 4 P04899,P63096,P09471 3 +Ribosomal protein S5 [IPR000851] 0.401236302332115 0.2738769205448334 0.7841792084291745 1.0 0.7946310601520366 2 P82675 1 +Oxysterol-binding protein [IPR000648] 0.4446789041070547 0.2694565952326117 0.7875783393011855 1.0 0.7977801312610454 5 Q96SU4 1 +RNA-binding protein 26/27 [IPR045137] 0.395054790671538 0.2564728074355342 0.7975857749199624 1.0 0.8070211704088491 2 Q9P2N5 1 +Ephrin receptor type-A /type-B [IPR016257] 0.3885923012082075 0.2390002494515617 0.8111053893114049 1.0 0.8194889075471816 2 Q15375 1 +Peptidase M3A/M3B [IPR045090] 0.4291736930860121 0.2058761925448538 0.8368876226751194 1.0 0.8439798906638916 3 Q9BYT8,Q99797 2 +Sec1-like protein [IPR001619] 0.4075949367088765 0.19392942426573 0.846231143812489 1.0 0.8527741681203175 6 O00186,Q8WVM8,Q9H267,Q96AX1,Q8WU76 5 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.3604945209328472 0.1719518959406146 0.8634753470805023 1.0 0.8698314409125267 2 O60884 1 +Pre-mRNA-splicing factor Syf1-like [IPR045075] 0.3864530635188378 0.1220367578435442 0.9028699072730716 1.0 0.9068458481491366 3 Q9BZJ0,Q9HCS7 2 +Small GTPase Rho [IPR003578] 0.3844206974128358 0.1191848045156666 0.905128945074022 1.0 0.908781336268378 5 P60953,P63000,Q8IXI1,Q8IXI2 4 +Phosphatidylinositol transfer protein [IPR001666] 0.3253722955886549 0.1090235395710957 0.913183819742328 1.0 0.9165324952822704 2 Q00169 1 +Nuclear pore complex protein [IPR026054] 0.369589657110744 0.0962931526678054 0.9232877491964387 1.0 0.9263337864921748 3 P35658,A8CG34 2 +Chaperone DnaJ [IPR012724] 0.3605958403597603 0.0842321471886674 0.9328718592416988 1.0 0.935606551390447 3 O60884,Q96EY1 2 +Ribosomal protein L1/ribosomal biogenesis protein [IPR028364] 0.3265879707701038 0.0484908784354153 0.9613250338457324 1.0 0.9637899698299522 3 O76021,Q9BYD6 2 +Dynein family light intermediate chain [IPR022780] 0.3234963462619525 0.0459616560416814 0.9633408116389016 1.0 0.965457268932872 3 Q9Y6G9,O43237 2 +RNA (C5-cytosine) methyltransferase [IPR023267] 0.3148720832161949 0.0207113634722909 0.9834759042250036 1.0 0.9852758235226337 4 P46087,Q96P11,Q9H649 3 +Copine [IPR045052] 0.270376616076455 0.0175785692986974 0.9859750532582984 1.0 0.9874181195638356 3 Q86YQ8,O75131 2 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bf46c3998fd3ca9c289c44eb4e117301764c804f --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1,4-alpha-glucan-branching enzyme [IPR037439]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 [IPR028406]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "14kDa phosphohistidine phosphatase [IPR028441]", "16S/18S rRNA aminocarboxypropyltransferase Tsr3 [IPR022968]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-oxoisovalerate dehydrogenase subunit alpha [IPR034616]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S26 [IPR026140]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-keto-steroid reductase [IPR042829]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "4-aminobutyrate aminotransferase, eukaryotic [IPR004631]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease 1 [IPR016494]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "AP-5 complex subunit mu-1 [IPR039591]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "ATR-interacting protein [IPR033349]", "Abr/Bcr [IPR037769]", "Acetate-CoA ligase [IPR011904]", "Acetoacetyl-CoA synthase [IPR005914]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 2/3 complex subunit 5 [IPR006789]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activating signal cointegrator 1-like [IPR039128]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "Adenylyltransferase and sulfurtransferase MOCS3/Uba4 [IPR028885]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAK [IPR026308]", "Apoptosis regulator, Mcl-1 [IPR013281]", "ArfGAP ACAP1/2/3-like [IPR045258]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arsenite methyltransferase-like [IPR026669]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 13 [IPR040182]", "Autophagy-related protein 5 [IPR007239]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BET1-like protein [IPR039897]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "BTB-kelch protein [IPR017096]", "BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1/2/3 [IPR045068]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-2-syntrophin [IPR028550]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-adducin [IPR027773]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biorientation of chromosomes in cell division protein 1-like 1 [IPR043244]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 10 [IPR039740]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDC50/LEM3 family [IPR005045]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGI121/TPRKB [IPR013926]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 2 [IPR037354]", "COMM domain-containing protein 4 [IPR037356]", "COMM domain-containing protein 7 [IPR037358]", "COMM domain-containing protein 9 [IPR037360]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome complex subunit 7B [IPR027530]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "CPSF6/7 family [IPR034772]", "CTD phosphatase Fcp1 [IPR039189]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calmodulin-regulated spectrin-associated protein [IPR032940]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Carboxymethylenebutenolidase homolog [IPR042946]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-2 [IPR035702]", "Caspase-8 [IPR033170]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cation/H+ exchanger, CPA1 family [IPR018422]", "Cationic amino acid transport permease [IPR004755]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle checkpoint, Hus1 [IPR016580]", "Cell cycle control protein 50A [IPR030351]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-K [IPR020993]", "Centromere protein I [IPR012485]", "Centromere protein Q [IPR025212]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 290kDa [IPR026201]", "Centrosomal protein of 44kDa [IPR033603]", "Centrosomal protein of 55kDa [IPR038926]", "Centrosome-associated protein 350 [IPR028750]", "Ceramide glucosyltransferase [IPR025993]", "Cerebellar degeneration-related protein 2 [IPR026079]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Checkpoint protein Hus1/Mec3 [IPR007150]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Choline transporter-like [IPR007603]", "Chondroitin N-acetylgalactosaminyltransferase [IPR008428]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homolog 2 [IPR042796]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cilia- and flagella-associated protein 298 [IPR021298]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Claspin [IPR024146]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 90-like [IPR024461]", "Coilin [IPR024822]", "Complex I intermediate-associated protein 30, mitochondrial [IPR039131]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Condensin-2 complex subunit H2 [IPR031739]", "Conserved oligomeric Golgi complex subunit 5 [IPR019465]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex subunit 8 [IPR007255]", "Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae [IPR016632]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Copper homeostasis protein CutC [IPR005627]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Core-binding factor, beta subunit [IPR003417]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclin/Cyclin-like subunit Ssn8 [IPR043198]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein COX14 [IPR029208]", "Cytochrome c oxidase assembly protein CtaG/Cox11 [IPR007533]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic dynein 2 light intermediate chain 1 [IPR040045]", "Cytoplasmic tRNA 2-thiolation protein 2 [IPR019407]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35 [IPR028601]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 8-like [IPR045151]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DIS3-like exonuclease 2 [IPR028591]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 40 [IPR039729]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase 4 [IPR029710]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair protein XPF [IPR006167]", "DNA repair protein XRCC4 [IPR010585]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase III subunit Rpc5 [IPR006886]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deltex family [IPR039398]", "Deoxycytidylate deaminase [IPR016473]", "Deoxycytidylate deaminase-related [IPR015517]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxynucleoside kinase [IPR002624]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydroxyacetone kinase [IPR012734]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylarginine dimethylaminohydrolase [IPR033199]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphosphomevalonate decarboxylase [IPR029765]", "Diphosphomevalonate/phosphomevalonate decarboxylase [IPR005935]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Dishevelled family [IPR008339]", "Dishevelled-2 [IPR008341]", "Dishevelled-related protein [IPR015506]", "Disks large 1-like [IPR016313]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dwarfin [IPR013790]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase KCMF1 [IPR039858]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF123/RSPRY1-like [IPR045129]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosome-associated-trafficking regulator 1 [IPR026757]", "Endosulphine [IPR006760]", "Endothelial protein C receptor [IPR015669]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Erg28 [IPR005352]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Est1/Ebs1-like [IPR045153]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Eyes absent family [IPR028472]", "Eyes absent homologue 4 [IPR028478]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "F-box-like/WD repeat-containing protein Ebi-like [IPR045183]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM91 [IPR039199]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FLYWCH-type zinc finger-containing protein 1/2 [IPR040312]", "Fanconi anaemia group A protein [IPR003516]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fas apoptotic inhibitory molecule 1 [IPR010695]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "FeS cluster insertion protein [IPR016092]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Focadhesin [IPR021392]", "Focadhesin/RST1 [IPR045163]", "Folylpolyglutamate synthase, eukaryota [IPR023600]", "Folylpolyglutamate synthetase [IPR001645]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "Fyv10 family [IPR045098]", "Fyv7/TAP26 [IPR013730]", "G patch domain-containing protein 11 [IPR039249]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "G2 and S phase-expressed protein 1 [IPR026659]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GMP reductase [IPR005993]", "GOLM1/CASC4 family [IPR026139]", "GPCR-associated sorting protein [IPR043374]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GPN-loop GTPase 1 [IPR030230]", "GPN-loop GTPase [IPR004130]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GRIP1-associated protein 1 [IPR026204]", "GTP cyclohydrolase 1 type 2/Nif3 [IPR002678]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "GTP-binding protein, ribosome biogenesis, YsxC [IPR019987]", "Galactokinase [IPR000705]", "Galanin precursor [IPR008175]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma tubulin [IPR002454]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gasdermin-E [IPR042377]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Gigaxonin [IPR030579]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glu-tRNAGln amidotransferase C subunit [IPR003837]", "Glucocorticoid receptor [IPR001409]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent [IPR006168]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic [IPR017751]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi membrane protein 1 [IPR026143]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 2 [IPR028346]", "HAUS augmin-like complex subunit 2, metazoa [IPR026242]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HCLS1-binding protein 3 [IPR039701]", "HEXIM [IPR024872]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Heat shock transcription factor family [IPR027725]", "Helicase MOV-10 [IPR026122]", "Helicase SMUBP-2/Hcs1-like [IPR004483]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETD2, animal [IPR042294]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "Histone-lysine N-methyltransferase, SET [IPR017155]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "Hypoxia-inducible factor 1-alpha inhibitor [IPR027445]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "IQ calmodulin-binding motif-containing protein 1 [IPR028765]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Innexin [IPR000990]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 1,4,5-trisphosphate receptor-interacting protein [IPR024797]", "Inositol 1,4,5-trisphosphate receptor-interacting protein family [IPR026250]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 10 [IPR026164]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 2 [IPR029321]", "Integrator complex subunit 2, metazoa [IPR026236]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 8 [IPR038751]", "Integrator complex subunit 9 [IPR027074]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interferon-stimulated 20kDa exonuclease-like 2 [IPR034933]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isochorismatase domain-containing protein 2 [IPR040318]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "Janus [IPR007702]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "K/Cl co-transporter 4 [IPR030354]", "K/Cl co-transporter [IPR000076]", "KAT8 regulatory NSL complex subunit 3/Testis-expressed sequence 30 protein [IPR026555]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Kelch-like ECH-associated protein 1 [IPR030563]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF15/KIN-12E [IPR044986]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Leo1-like protein [IPR007149]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper protein 1 [IPR026734]", "Leucine zipper putative tumor suppressor [IPR045329]", "Leucine zipper putative tumour suppressor 2 [IPR028597]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte elastase inhibitor (serpin B1) [IPR015557]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipid droplet-associated hydrolase [IPR019363]", "Liprin-alpha-1 [IPR030438]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase inducer phosphatase [IPR000751]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICAL3 [IPR029941]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MIOS/Sea4 [IPR037593]", "MKRN-like [IPR045072]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macoilin [IPR019130]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter protein 1 [IPR006844]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Mannosyltransferase ALG2 [IPR027054]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med27 [IPR021627]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D1 [IPR030083]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Menin [IPR007747]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthioribulose-1-phosphate dehydratase [IPR017714]", "Methylthioribulose-1-phosphate dehydratase, eukaryotes [IPR027514]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase Ppm1/Ppm2/Tcmp [IPR007213]", "Mevalonate kinase [IPR006205]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein 9 [IPR026106]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial calcium uniporter regulator 1 [IPR012439]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein Mtm1-like [IPR045315]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial mRNA pseudouridine synthase Trub2 [IPR039048]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Mucosa-associated lymphoid tissue lymphoma translocation protein 1 [IPR033540]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Multivesicular body subunit 12 [IPR018798]", "Multivesicular body subunit 12A [IPR040335]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 14 [IPR039802]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 [IPR033202]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase MT-A70-like [IPR025848]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B/Dorsal [IPR000451]", "NIF3-like protein 1, animal [IPR017222]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Na+/H+ exchanger [IPR004709]", "Na+/H+ exchanger, isoform 6/7/9 [IPR002090]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Neogenin [IPR033024]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurabin-2 [IPR029921]", "Neurabin-like family [IPR043446]", "Neural Wiskott-Aldrich syndrome protein [IPR030214]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neurogenic locus Notch 2 [IPR022336]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Neuroplastin [IPR027112]", "Neutral amino acid SLC6 transporter [IPR002438]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Notch [IPR008297]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 2 [IPR027157]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear factor related to kappa-B-binding protein [IPR024867]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear hormone receptor [IPR001723]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear pore protein POM121 [IPR026090]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "ORC ubiquitin ligase 1 [IPR039209]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IB [IPR027256]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein GIPC1/2/3 [IPR017379]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Palmitoyltransferase ZDHHC13 [IPR030290]", "Pannexin [IPR039099]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic antigen Ma2 [IPR026525]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Partner of Y14 and mago [IPR039333]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1 [IPR028606]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Pre-rRNA-processing protein TSR2 [IPR019398]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Proline/serine-rich coiled-coil protein 1/G2 and S phase-expressed protein 1 [IPR026657]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein C10 [IPR026317]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM234 [IPR045232]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein Fyv10/E3 ubiquitin-protein transferase MAEA [IPR027714]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein KTI12/L-seryl-tRNA(Sec) kinase [IPR013641]", "Protein Kti12 [IPR045106]", "Protein LCHN/Anr2 [IPR018626]", "Protein LYRIC [IPR031402]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sec13 [IPR037596]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C [IPR012233]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1387 [IPR009816]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4507 [IPR027844]", "Protein of unknown function DUF4559 [IPR027897]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF4726 [IPR031714]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein strawberry notch [IPR026741]", "Protein suppressor of sable-like [IPR045124]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein wntless [IPR009551]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA-binding protein 47 [IPR034442]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxamine 5'-phosphate oxidase [IPR000659]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAD3/XPD family [IPR001945]", "RAD51-associated protein 1 [IPR026632]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cap guanine-N2 methyltransferase [IPR019012]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase, Rpb8 [IPR005570]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-1 [IPR033086]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab protein geranylgeranyltransferase component A [IPR001738]", "Rab-like protein 6 [IPR040385]", "Rab12 [IPR041830]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "Ral GTPase-activating protein subunit beta [IPR039930]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Regulatory associated protein of TOR [IPR004083]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulon-4-interacting protein 1 [IPR037397]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma protein family [IPR028309]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retinoblastoma-like protein 1 [IPR028310]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho GDP/GTP exchange factor Kalirin/TRIO [IPR028570]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Riboflavin kinase [IPR023468]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleases P/MRP protein subunit Rpp20/Pop7 [IPR014612]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis factor [IPR031389]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27 [IPR001684]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3 domain-binding protein 4 [IPR035455]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNARE associated Golgi protein [IPR032816]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SSNA1 family [IPR033362]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sds3-like [IPR013907]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 8 [IPR030646]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Ser/Thr protein kinase, TGFB receptor [IPR000333]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 2-like [IPR034893]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase Atg1-like [IPR045269]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase SMG1 [IPR031559]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase TOUSLED-like 2 [IPR027086]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shikimate kinase/Threonine synthase-like 1 [IPR000623]", "Shikimate kinase/gluconokinase [IPR031322]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sm-like protein Lsm6/SmF [IPR016487]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermatogenesis-defective protein 39 [IPR040057]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingolipid delta(4)-desaturase DES1 [IPR031196]", "Sphingolipid delta4-desaturase [IPR011388]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 1 [IPR009829]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol regulatory element-binding protein cleavage-activating protein [IPR030225]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syndetin [IPR040047]", "Syntaxin [IPR045242]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "Syntrophin [IPR015482]", "T-complex 11 [IPR008862]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TB2/DP1/HVA22-related protein [IPR004345]", "TBC1 domain family member 24 [IPR040149]", "TCF25/Rqc1 [IPR006994]", "TE2IP/Rap1 [IPR039595]", "TEL2-interacting protein 1 [IPR016441]", "TFIIH subunit Tfb1/GTF2H1 [IPR027079]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM115/Pdh1/Rbl19 [IPR013861]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TNF receptor-associated factor 2 [IPR027133]", "TNF receptor-associated factor TRAF [IPR043211]", "TNF receptor-associated factor TRAF, metazoa [IPR012227]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "TSC-22 / Dip / Bun [IPR000580]", "Target of Myb protein 1 [IPR014645]", "Target of Myb1-like 2 [IPR027429]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetracycline resistance protein TetA/multidrug resistance protein MdtG [IPR001958]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiamine triphosphatase, eukaryotes [IPR012177]", "Thiamine-triphosphatase [IPR039582]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 16 [IPR040090]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine synthase-like [IPR004450]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor RelA (p65) [IPR030495]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor TFIIH subunit p52/Tfb2 [IPR004598]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, enhancer of yellow 2 [IPR018783]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor TFIID subunit 2 [IPR037813]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription initiation factor TFIID, 23-30kDa subunit [IPR003923]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation machinery associated TMA7 [IPR015157]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Translocon-associated protein subunit gamma [IPR009779]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 41A/B [IPR045014]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Trimethyllysine dioxygenase [IPR012776]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tti2 family [IPR018870]", "Tuberin [IPR003913]", "Tuberin/Ral GTPase-activating protein subunit alpha [IPR027107]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-protein phosphatase non-receptor type 13 [IPR012153]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm1/8 [IPR044642]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronic acid decarboxylase [IPR044516]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquilin-1/2 [IPR028430]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-conjugating enzyme E2-binding protein [IPR019193]", "Ubiquitin-fold modifier 1 [IPR005375]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised protein family UPF0390 [IPR019034]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0640 [IPR028183]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-IXb [IPR028557]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "VPS35 endosomal protein sorting factor-like [IPR029705]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated Vps28 [IPR007143]", "Vacuolar protein sorting-associated protein 11 [IPR016528]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle transport protein, Use1 [IPR019150]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vinexin [IPR028510]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps52 [IPR007258]", "WASH complex subunit 3 [IPR019309]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR48/Bun107 [IPR021772]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger ZZ-type and EF-hand domain-containing protein 1 [IPR040099]", "Zinc finger protein 277 [IPR040048]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA capping enzyme, bifunctional [IPR017074]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "siRNA-mediated silencing protein NRDE-2 [IPR013633]", "tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 [IPR014816]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [IPR004416]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related [IPR002218]", "tRNA-specific 2-thiouridylase [IPR004506]", "tRNAHis guanylyltransferase Thg1 [IPR007537]"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAR2", "AARS", "AARS2", "AATF", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABHD12", "ABT1", "ACAA1", "ACAA2", "ACADM", "ACAP2", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACSS1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKT1S1", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANKLE2", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP5M1", "APEX1", "API5", "APIP", "APLP2", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFIP1", "ARFIP2", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG13", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATXN2L", "AURKA", "AURKB", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BAK1", "BANF1", "BASP1", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRI3BP", "BRIP1", "BRIX1", "BRMS1L", "BROX", "BSG", "BTF3", "BUB1B", "BUD31", "BYSL", "C12orf43", "C12orf57", "C12orf73", "C16orf58", "C16orf62", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "C7orf26", "C8orf33", "C8orf59", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASP2", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX2", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC59", "CCDC6", "CCDC8", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK5RAP3", "CDK6", "CDKAL1", "CDR2L", "CDS2", "CDV3", "CEBPZ", "CELF2", "CENPI", "CENPK", "CENPQ", "CEP170", "CEP290", "CEP350", "CEP44", "CEP55", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHML", "CHMP1A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIP2A", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMMD2", "COMMD4", "COMMD7", "COMMD9", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSGALNACT2", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWC27", "CWF19L1", "CXorf38", "CXorf56", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DFFB", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIS3L2", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EFHD1", "EFHD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "ENDOD1", "ENO1", "ENO2", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERG28", "ERGIC1", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EYA4", "EZR", "F11R", "FADS2", "FAH", "FAIM", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM213A", "FAM234B", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FN3KRP", "FOCAD", "FPGS", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAL", "GALK1", "GALM", "GAN", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMFB", "GMPR2", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPATCH11", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPX8", "GRIPAP1", "GRPEL1", "GRSF1", "GSDME", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "GXYLT1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDHD2", "HDHD5", "HEATR1", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP2", "IGHMBP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS10", "INTS13", "INTS14", "INTS2", "INTS3", "INTS5", "INTS8", "INTS9", "IPO4", "IPO5", "IQCB1", "IRGQ", "IRS4", "ISCA2", "ISG20L2", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2B", "ITPA", "ITPRIP", "ITSN2", "IVD", "JAGN1", "JPT2", "JUP", "KANSL3", "KARS", "KCMF1", "KCTD10", "KDELR1", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LEO1", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIG4", "LIMA1", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LNPK", "LONP1", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LSM12", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MALT1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP4", "MAP7D3", "MAP9", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED16", "MED17", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL16", "METTL3", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD5", "MFSD8", "MGEA5", "MGST2", "MGST3", "MICAL3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKRN2", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MOCS1", "MOCS3", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPST", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTR", "MTX1", "MTX2", "MVB12A", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF1", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NEO1", "NES", "NF1", "NFRKB", "NFS1", "NHP2", "NIF3L1", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRDE2", "NRM", "NRP1", "NSA2", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN3", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "ODR4", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAK2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PAPSS2", "PARG", "PARK7", "PARN", "PATL1", "PAWR", "PBDC1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHPT1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PLA2G15", "PLBD2", "PLCD3", "PLCG1", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPO", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLD2", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POM121C", "PON2", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP1R9B", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKCZ", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBL1", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM45", "RBM47", "RBM5", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "REXO4", "RFC1", "RFK", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX2", "RMND5A", "RNASEH2A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTFDC1", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SBNO1", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCAP", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCLY", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLC9A6", "SLFN11", "SLK", "SMAD4", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG1", "SMG5", "SMG8", "SMIM4", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SPAG9", "SPART", "SPATS2L", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPPL2A", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF2", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STARD3", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF10", "TAF2", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBC1D24", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TCP11L1", "TECR", "TEDC1", "TEFM", "TERF2", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGS1", "THG1L", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THTPA", "THUMPD1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TLE3", "TLK2", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM41A", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMX2", "TNPO1", "TNPO2", "TOE1", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPRKB", "TPT1", "TPX2", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIO", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSC22D3", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TSR3", "TSTA3", "TTC19", "TTC27", "TTC37", "TTC38", "TTI1", "TTI2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2", "UBAP2L", "UBE3A", "UBE3C", "UBE3D", "UBE4A", "UBE4B", "UBFD1", "UBL5", "UBQLN1", "UBR4", "UBR7", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USE1", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "UXS1", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", 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b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:befde29b7b2c649fea06f6f044ac74f8a8a71925f29824f7f1c2931ce1145ae3 +size 285156 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d08208e290e91e74792b694a5c77dc2cffdb6edb --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,8 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier domain superfamily [IPR023395] 19 23 3.4940938274724385 0.0004756738101701 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 5.660513393058556e-10 1.0 0.0053755248402168 7.339182273039057e-10 3.341464831402234e-13 +Alpha/Beta hydrolase fold [IPR029058] 10 25 2.605574894756621 0.009172021884783 7.793689320388349 25.487864077669904 0.3803730368869525 0.1931612116461074 2.8504230618688027 2.5849355029363217 1.9090082785106757 0.2379814650369476 0.0001473041142768 0.0380395748305272 3.739088907387951e-05 0.0001747163892271 0.0003146391614106 +Band 7/SPFH domain superfamily [IPR036013] 5 8 2.056946434709765 0.0396913786697714 3.825242718446602 7.354368932038835 0.2848798017769268 0.3662852929750465 1.8717479731706237 0.7075565364256523 1.25010454777189 0.3076860385713043 0.1598723880146802 1.0 1.0 0.0222658144313338 0.0102762365494686 +P-type ATPase, A domain superfamily [IPR008250] 3 8 2.0539743393309315 0.0399781753779207 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0546082347726425 1.0 1.0 0.0145721558996701 0.0193421266882966 +P-type ATPase, transmembrane domain superfamily [IPR023298] 3 8 2.0539743393309315 0.0399781753779207 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0591475015489903 1.0 1.0 0.0164697860130212 0.0225482630910853 +P-type ATPase, cytoplasmic domain N [IPR023299] 3 8 2.0539743393309315 0.0399781753779207 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0546082347726425 1.0 1.0 0.0145721558996701 0.0193421266882966 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 4 7 2.03612007038049 0.0417382998244963 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0174535696320652 0.0539630923046902 0.1073692926764015 0.000131895504155 0.0001501374850564 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9c211ca14b4705a02aff406007fbd3a9650b73b0 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 1030, + "title": "Average number of proteins per term", + "value": 5.072815533980583 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c4c06d529b594a0f2f098f63854f38099aae339d --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e2c635eee47a0dd2f0baf0f5822724bc3e1d6858 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,132 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier domain superfamily [IPR023395] 0.807859110244296 3.4940938274724385 0.0004756738101701 0.3874107226285918 0.0034981322126135 23 Q9NZJ7,P53007,Q9HC21,Q86VD7,Q6NUK1,P12235,P05141,Q6KCM7,Q70HW3,O43772,Q9BSK2,Q8TBP6,Q02978,Q9UJS0,O43808,Q9H2D1,P12236,Q9UBX3,Q9Y6C9 19 +Cytochrome P450 superfamily [IPR036396] 0.9935375105366676 2.8440793646553972 0.0044539952120445 0.9899266515924936 0.0175770692276089 2 Q16850 1 +Haem oxygenase-like, multi-helical [IPR016084] 0.9820174206237696 2.795865051999782 0.0051761008437225 0.9952291441073596 0.0199603110604544 2 P30519 1 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.9634728856420324 2.7177135418341054 0.0065734722105679 0.9988784322641098 0.0236736936254718 2 O60637 1 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.9491430177015991 2.6568669552968105 0.0078870562420234 0.9997129554968476 0.0271694579574721 2 Q15392 1 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.9491430177015991 2.6568669552968105 0.0078870562420234 0.9997129554968476 0.0271694579574721 2 Q15392 1 +Alpha/Beta hydrolase fold [IPR029058] 0.6419596575207174 2.6055748947566215 0.009172021884783 0.9999244544050626 0.0305734062826101 25 P10619,Q9UMR5,Q8NCC3,Q9H3G5,Q9H6V9,P07099,P50897,Q9NUJ1,P42785,Q9HB40 10 +Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352] 0.8645686990727705 2.28962883303116 0.0220428420922962 0.99999999989299 0.0583653659513242 2 Q99735 1 +Tim10-like domain superfamily [IPR035427] 0.8204551840404533 2.092676309506753 0.0363780594426126 1.0 0.0845810411419661 2 Q9Y5J6 1 +Band 7/SPFH domain superfamily [IPR036013] 0.7669770146684098 2.0569464347097655 0.0396913786697714 1.0 0.090091827351662 8 O75955,Q14254,Q99623,P27105,O75477 5 +LAP1C-like, C-terminal domain superfamily [IPR038599] 0.8120258499578473 2.0546406756400506 0.0399137238425988 1.0 0.090091827351662 2 Q5JTV8 1 +P-type ATPase, A domain superfamily [IPR008250] 0.7663249917016802 2.0539743393309315 0.0399781753779207 1.0 0.090091827351662 8 Q9HD20,P16615,P35670 3 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7663249917016802 2.0539743393309315 0.0399781753779207 1.0 0.090091827351662 8 Q9HD20,P16615,P35670 3 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7663249917016802 2.0539743393309315 0.0399781753779207 1.0 0.090091827351662 8 Q9HD20,P16615,P35670 3 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.8160500251344298 2.03612007038049 0.0417382998244963 1.0 0.0922541820155177 7 O95864,O15173,O00264,O43169 4 +Ribosomal protein L13 superfamily [IPR036899] 0.8064062939027739 2.0292146985862543 0.0424364271006627 1.0 0.0931709617416805 2 Q9BYD1 1 +Chloride channel, core [IPR014743] 0.8021916268614736 2.0101095955163255 0.0444195907162221 1.0 0.0963304794452733 2 P51790 1 +Porin domain superfamily [IPR023614] 0.9156592634242284 2.006960016850448 0.0447539204836975 1.0 0.0966384446503322 4 P45880,Q9Y277,P21796 3 +G-protein gamma-like domain superfamily [IPR036284] 0.7960101152008968 1.982034356182484 0.0474753955677951 1.0 0.1012415267801842 2 Q9UBI6 1 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.9030354131534588 1.9787041843310111 0.0478493215850075 1.0 0.1018281017201606 3 Q13432,O43924 2 +Ribosomal protein L37ae/L37e [IPR011331] 0.7805563360494482 1.911570650434471 0.0559312868250887 1.0 0.1120802051164229 2 P61513 1 +LEM/LEM-like domain superfamily [IPR011015] 0.8206464150816255 1.8313539315259564 0.0670477327075695 1.0 0.127650951365613 6 P42167,Q86XL3 2 +Lamin tail domain superfamily [IPR036415] 0.8552557616638574 1.7878036754896085 0.0738076876867197 1.0 0.1379708136430514 3 P20700,P02545 2 +Rhomboid-like superfamily [IPR035952] 0.8532471183581587 1.7613959697945898 0.0781714066975844 1.0 0.1450748628802018 4 Q6NTF9,Q9BUN8,Q9GZP9 3 +Peptidase M41-like [IPR037219] 0.7420623770722058 1.7344745171879288 0.0828339233935697 1.0 0.1523552519560301 2 Q96TA2 1 +SNARE [IPR010989] 0.7966613280756261 1.7321015832160844 0.0832554773654448 1.0 0.1527684956365018 6 Q86Y82,O60499,O15400,Q12846 4 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.6899291314635734 1.699306647527114 0.0892614207195645 1.0 0.1590644694483589 8 P28288,O14678,Q03518,P08183,Q03519 5 +NAP-like superfamily [IPR037231] 0.8356319943026382 1.6912263966614496 0.0907935713275116 1.0 0.1615153341404784 4 Q01105,Q99733 2 +EF-hand domain pair [IPR011992] 0.4380788936692343 1.6660165407620735 0.0957101199671397 1.0 0.1679410963648278 57 Q8NF37,O75071,Q9BRK5,Q9H223,Q9Y680,Q9NWM8,Q6KCM7,P80303,O43852,O95202,Q9UBC2,Q6NUK1,Q14257,Q02818,Q9UJS0,P41208 16 +START-like domain superfamily [IPR023393] 0.7957660592274396 1.639365621007938 0.1011371370468188 1.0 0.1759649512807827 5 Q14849 1 +CRAL/TRIO, N-terminal domain superfamily [IPR036273] 0.8130939820229777 1.6171888047494456 0.1058375321700779 1.0 0.1829071445221146 3 O76054 1 +FF domain superfamily [IPR036517] 0.7055352627142464 1.564705037014723 0.1176520868904016 1.0 0.1989846461364756 2 O75400 1 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.5203453474683841 1.559384958502412 0.1189052942080057 1.0 0.1997919299090472 20 Q8N4A0,Q10472,Q16739 3 +GINS, helical bundle-like domain superfamily [IPR036224] 0.7964494794542564 1.5493859157508854 0.1212889774370302 1.0 0.2024759266777004 3 Q9Y248 1 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.6982849038271427 1.5184815450611464 0.1288930484200938 1.0 0.2120764215218796 7 P09960 1 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.6982849038271427 1.5184815450611464 0.1288930484200938 1.0 0.2120764215218796 7 P09960 1 +Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919] 0.6920483281820665 1.5017131247540818 0.1331712128295059 1.0 0.2150160489728985 2 P18124 1 +Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702] 0.6917673503793189 1.500399505571516 0.1335109475395448 1.0 0.2152054396959799 2 P05026 1 +PD-(D/E)XK endonuclease-like domain superfamily [IPR011604] 0.6898005057600439 1.4912028948842966 0.1359082338781612 1.0 0.2183860856388549 2 Q9BQP7 1 +Zinc-binding ribosomal protein [IPR011332] 0.780775716694775 1.4853588660176271 0.1374487859188315 1.0 0.2197727733276702 3 P83881,P61513 2 +Ribosomal protein L10e/L16 superfamily [IPR036920] 0.6810901938746755 1.4504512439952295 0.1469327259698345 1.0 0.2275164515030763 2 P27635 1 +Ricin B-like lectins [IPR035992] 0.7556242023731381 1.3689992577643555 0.1709995069233092 1.0 0.2582543872888688 4 Q10472 1 +Calreticulin/calnexin, P domain superfamily [IPR009033] 0.7315688738063812 1.2837183194259447 0.1992405321466654 1.0 0.2915024831123088 3 P27824 1 +Ribosomal L18e/L15P superfamily [IPR036227] 0.7276559865092785 1.267675893206731 0.2049137170594202 1.0 0.2972691951707081 3 Q07020,P46776 2 +Histidine phosphatase superfamily [IPR029033] 0.6831906650590792 1.2533745682522048 0.2100694223481429 1.0 0.3027580339618802 6 Q9NPH0 1 +PUA domain superfamily [IPR036974] 0.638943523461642 1.2531064067803614 0.2101669847405285 1.0 0.3027580339618802 2 Q9Y221 1 +Immunoglobulin-like domain superfamily [IPR036179] 0.4960680811273154 1.2517338365453992 0.2106668661836261 1.0 0.3030542907390153 17 P35613,P01889,O75962,P10586,Q08722,Q9Y639,P10321,Q9BY67,P55899 9 +HAD-like superfamily [IPR036412] 0.4498282400782695 1.2268713938855569 0.2198709317899081 1.0 0.3145375829772296 24 P05023,Q9BXW7,P16615,Q9H857,Q96T60,Q9H0P0,P35670,P20020,Q9HD20,Q969T7 10 +HAD superfamily [IPR023214] 0.4498282400782695 1.2268713938855569 0.2198709317899081 1.0 0.3145375829772296 24 P05023,Q9BXW7,P16615,Q9H857,Q96T60,Q9H0P0,P35670,P20020,Q9HD20,Q969T7 10 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.6937238891755872 1.2162200915019696 0.223901092071806 1.0 0.3176558193305238 5 P01889,P10321 2 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.6937238891755872 1.2162200915019696 0.223901092071806 1.0 0.3176558193305238 5 P01889,P10321 2 +EB1, C-terminal domain superfamily [IPR036133] 0.6220848552964258 1.1743706901451787 0.2402465798772999 1.0 0.3381348842226024 2 Q15555 1 +RGS, subdomain 2 [IPR044926] 0.6164652992413538 1.1481910545503609 0.2508897013215887 1.0 0.3511092287516799 2 Q92888 1 +Hemimethylated DNA-binding domain superfamily [IPR036623] 0.6139364990165714 1.136423860052581 0.2557792146523114 1.0 0.3550574003933703 2 Q9Y2S7 1 +Homeobox-like domain superfamily [IPR009057] 0.4690754682633518 1.1303923013190411 0.2583109566789323 1.0 0.3566491761116626 18 Q8N5B7,Q96KC8,Q96G23 3 +Immunoglobulin E-set [IPR014756] 0.4553310380442191 1.1207786767778167 0.2623820827784282 1.0 0.3617852011536561 20 O43924 1 +MFS transporter superfamily [IPR036259] 0.5577953327217486 1.062978859929638 0.2877915383150184 1.0 0.3900332690321961 8 Q5SR56,Q8NHS3,Q7L0J3,Q14728 4 +SCP2 sterol-binding domain superfamily [IPR036527] 0.6593591905564972 0.9893505532789024 0.3224916580937644 1.0 0.4319459139617391 3 P51659,Q6YN16 2 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.6601312942073765 0.9830588472194162 0.3255784767958762 1.0 0.4349491972759436 4 P42892 1 +Translation protein SH3-like domain superfamily [IPR008991] 0.5009157477282705 0.9776262086129934 0.3282592300247473 1.0 0.4379624442040022 11 P46778,Q02878,P62917,Q5T653,P49406,Q96A35 6 +Longin-like domain superfamily [IPR011012] 0.4791431792559011 0.9614480041416652 0.3363269573788305 1.0 0.4458388238097754 13 Q9Y2T2,Q96CW1,O15498,P48444,P61966,P51809,P08240,P56377,Q9Y296,O75396,Q92572,P53680 12 +Cobalamin-binding domain superfamily [IPR036724] 0.5729137398145456 0.947300217208261 0.343485820192636 1.0 0.4535774292287374 2 P22033 1 +Bcl-2-like superfamily [IPR036834] 0.6486051064899601 0.9370708556363668 0.3487221117820005 1.0 0.4593142904545531 4 Q9BXK5 1 +Ribosomal protein L23/L15e core domain superfamily [IPR012678] 0.637967634641046 0.9035870655076244 0.3662144023764415 1.0 0.474760529526276 3 P61313 1 +GOLD domain superfamily [IPR036598] 0.6181246414639385 0.9031592540837045 0.366441379585815 1.0 0.474760529526276 5 Q15363,O76054 2 +HORMA domain superfamily [IPR036570] 0.55577409384658 0.8697338078628829 0.3844458920896052 1.0 0.4949740860653667 2 Q13257 1 +GroES-like superfamily [IPR011032] 0.4881735573038089 0.8649500500903611 0.3870662051066842 1.0 0.4964294191511132 10 Q8N4Q0 1 +Moesin tail domain superfamily [IPR008954] 0.6225489465574123 0.8424989684383467 0.3995087168687756 1.0 0.5092747257114343 3 P35241 1 +HIV integrase-binding domain superfamily [IPR036218] 0.5439730261309246 0.817038210373605 0.4139065921430345 1.0 0.5250292979154255 2 Q7Z4V5 1 +Integrin domain superfamily [IPR032695] 0.5436920483281747 0.8157916337858676 0.4146193190351832 1.0 0.5252864681503552 2 P23229 1 +ISWI, HAND domain superfamily [IPR036306] 0.5428491149199125 0.812054291493915 0.4167604793773511 1.0 0.5267034279247506 2 O60264 1 +Vps16, C-terminal domain superfamily [IPR038132] 0.538634447878607 0.7934225672917581 0.4275316668309714 1.0 0.5358382245043725 2 Q9H9C1 1 +Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155] 0.5383534700758593 0.7921837868044723 0.4282535208159055 1.0 0.5358382245043725 2 Q96AX1 1 +Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179] 0.5254284911491873 0.7356850159583418 0.4619224106089701 1.0 0.5657313709004034 2 Q96HY7 1 +ARFGAP/RecO-like zinc finger [IPR037278] 0.5884036891745297 0.7101935369785675 0.4775841281647366 1.0 0.5772837874827941 3 Q15057 1 +ArfGAP domain superfamily [IPR038508] 0.5884036891745297 0.7101935369785675 0.4775841281647366 1.0 0.5772837874827941 3 Q15057 1 +NET domain superfamily [IPR038336] 0.5158752458555744 0.6945948006612048 0.4873092715395755 1.0 0.5856809214536322 2 Q15059 1 +CRAL-TRIO lipid binding domain superfamily [IPR036865] 0.533274610576024 0.626891776664967 0.5307301780407441 1.0 0.6243196355450328 6 O76054,P43378 2 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.4992757819098196 0.6260171185990554 0.5313037131010794 1.0 0.6243196355450328 7 Q13423,Q8IXJ6 2 +Ribosomal protein S11 superfamily [IPR036967] 0.49648777746557 0.6132604408836035 0.5397041459859362 1.0 0.6324178274920527 2 P82912 1 +Catenin binding domain superfamily [IPR027397] 0.5609341717729915 0.6077545778620981 0.5433502590051087 1.0 0.6350296388898232 3 Q14574 1 +Cadherin-like superfamily [IPR015919] 0.5609341717729915 0.6077545778620981 0.5433502590051087 1.0 0.6350296388898232 3 Q14574 1 +RmlC-like jelly roll fold [IPR014710] 0.4346193065352654 0.593044946780501 0.5531510725724582 1.0 0.6430537299657245 10 O00625,P38435,Q6P4Q7 3 +NAD(P)-binding domain superfamily [IPR036291] 0.3255014377601757 0.5879445889804268 0.5565694862281205 1.0 0.6443517048580415 70 Q8N335,P51659,Q8NBZ7,Q06136,Q96LJ7,Q8WVX9,Q9NRG7,Q53GQ0,Q8TC12,Q96K12,Q9BY49,Q15738,Q8N4Q0,Q9Y394,Q8NBN7,Q6IAN0,Q16836,Q16795,Q13423,Q8N8N7,Q3SXM5,Q99536,Q8WWV3,P40939 24 +Galactose mutarotase-like domain superfamily [IPR011013] 0.5287652891569864 0.5514825966454312 0.5813028936206199 1.0 0.6630586715716927 5 P10253 1 +RmlC-like cupin domain superfamily [IPR011051] 0.5406148370203565 0.5274882888997291 0.5978545469196113 1.0 0.6752085343499995 4 O00625,P38435 2 +HSP90, C-terminal domain [IPR037196] 0.5316277762159005 0.4961936931815068 0.6197577602536575 1.0 0.6968891845647022 4 P07900,P08238,Q12931 3 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.3525535443979528 0.460933964467918 0.6448459830239803 1.0 0.7211632600593917 22 Q6NUM9,Q9UHG3,Q14534 3 +Peptidyl-tRNA hydrolase II domain superfamily [IPR023476] 0.4518123068277594 0.4393639647659078 0.6603978328448226 1.0 0.7361577573919559 2 Q9Y3E5 1 +Alba-like domain superfamily [IPR036882] 0.4501264400112356 0.433250628895409 0.6648327012841602 1.0 0.7403001971056054 2 Q8N5L8 1 +Ribosomal protein S7 domain superfamily [IPR036823] 0.4487215509974691 0.4281844310678236 0.6685168503546579 1.0 0.7427965003940643 2 Q9Y2R9 1 +XPC-binding domain superfamily [IPR036353] 0.445068839561666 0.4151345019985649 0.6780434434270048 1.0 0.7525697701829903 2 P54727 1 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.4780652418447801 0.3731517575376457 0.7090354990767032 1.0 0.7810765390898441 5 Q9Y2T2,Q96CW1,P48444,Q9H0R1 4 +Ribosomal protein L14 superfamily [IPR036853] 0.4318628828322557 0.3694912137353941 0.711761621002845 1.0 0.7815757217722954 2 Q6P1L8 1 +G protein alpha subunit, helical insertion [IPR011025] 0.4635724331927 0.3673026252616968 0.713393296065876 1.0 0.7815757217722954 6 P04899,P63096,P29992,Q14344,P09471 5 +PapD-like superfamily [IPR008962] 0.4893198426082146 0.3664336569863182 0.7140415089201262 1.0 0.7815757217722954 3 Q8NHP6,Q9P0L0 2 +YEATS superfamily [IPR038704] 0.4301770160157332 0.363845079510003 0.7159736978371372 1.0 0.7820845079687213 2 O95619 1 +MAN1, winged-helix domain [IPR041885] 0.4279291935937043 0.3563828743773092 0.7215538528416392 1.0 0.7864555221448554 2 Q9Y2U8 1 +Nop domain superfamily [IPR036070] 0.4758291174817373 0.3265150380596753 0.7440347134855136 1.0 0.8024667590472032 3 Q8WWY3,Q9Y2X3 2 +Nop, C-terminal domain [IPR042239] 0.4758291174817373 0.3265150380596753 0.7440347134855136 1.0 0.8024667590472032 3 Q8WWY3,Q9Y2X3 2 +Cyclic nucleotide-binding-like [IPR018490] 0.4622414730201253 0.3224214804244908 0.7471334133545584 1.0 0.8032854026672183 5 Q6P4Q7 1 +Arp2/3 complex subunit 2/4 [IPR034666] 0.4144422590615331 0.3132480328710446 0.7540922283780092 1.0 0.8081510846086313 2 P59998 1 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.4184282534408038 0.3070398198461159 0.7588130632577696 1.0 0.8116069108572198 7 P22695,Q10713 2 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.4606520517144544 0.2841771450691384 0.776274629349589 1.0 0.8251422788752082 3 P61289,Q9UL46 2 +Proteasome activator superfamily [IPR036252] 0.4606520517144544 0.2841771450691384 0.776274629349589 1.0 0.8251422788752082 3 P61289,Q9UL46 2 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.4606520517144544 0.2841771450691384 0.776274629349589 1.0 0.8251422788752082 3 P61289,Q9UL46 2 +Glycoside hydrolase superfamily [IPR017853] 0.3378296003779446 0.2783794189407702 0.7807211166576284 1.0 0.8284271236573929 17 P04062,P08195,P10253,P16278,Q9BWS9,P54802,P08236 7 +RNA-binding S4 domain superfamily [IPR036986] 0.461906100646604 0.2780505808032417 0.7809735311372121 1.0 0.8284271236573929 4 Q9Y2Z4,P46781,Q9NV31 3 +HotDog domain superfamily [IPR029069] 0.4345528078130487 0.2725164393226211 0.7852249526866737 1.0 0.8320799395753846 6 P51659,Q9Y305 2 +Oxysterol-binding protein superfamily [IPR037239] 0.4446789041070547 0.2694565952326117 0.7875783393011855 1.0 0.8337160220762806 5 Q96SU4 1 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.4291736930860121 0.2058761925448538 0.8368876226751194 1.0 0.8760104180440783 3 Q9BYT8,Q99797 2 +GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266] 0.4249578414839858 0.1964250604193492 0.8442774829305493 1.0 0.8801678212737507 3 Q5T440,Q8NCN5 2 +Sec1-like superfamily [IPR036045] 0.4075949367088765 0.19392942426573 0.846231143812489 1.0 0.880422301138246 6 O00186,Q8WVM8,Q9H267,Q96AX1,Q8WU76 5 +Sec1-like, domain 2 [IPR027482] 0.4075949367088765 0.19392942426573 0.846231143812489 1.0 0.880422301138246 6 O00186,Q8WVM8,Q9H267,Q96AX1,Q8WU76 5 +NTF2-like domain superfamily [IPR032710] 0.3836547262788068 0.1926689468219538 0.847218244598658 1.0 0.8805598304103106 7 O43615 1 +Sec1-like, domain 3a [IPR043127] 0.4074803149606422 0.1705007371387055 0.864616354698482 1.0 0.8950299953160165 5 O00186,Q9H267,Q96AX1,Q8WVM8 4 +Sec1-like, domain 1 [IPR043154] 0.4074803149606422 0.1705007371387055 0.864616354698482 1.0 0.8950299953160165 5 O00186,Q9H267,Q96AX1,Q8WVM8 4 +PWI domain superfamily [IPR036483] 0.4120292299044469 0.16903185970019 0.8657715815394562 1.0 0.8953260331181124 3 O43395,Q8IYB3 2 +Cullin repeat-like-containing domain superfamily [IPR016159] 0.3379329766263075 0.1664593784907883 0.8677954483967731 1.0 0.8965188684540385 10 Q8IYI6,Q9UID3,Q13616,Q9UPT5,Q13619,Q13620,Q13617,Q96MW5,Q13618 9 +BSD domain superfamily [IPR035925] 0.3979763912310344 0.1420197137781542 0.8870644341752576 1.0 0.9128162459093072 3 Q9NW68,Q96A49 2 +AH/BAR domain superfamily [IPR027267] 0.3149675783704746 0.1338941824624448 0.8934862505860719 1.0 0.9184539302431676 14 Q9UQB8,Q15057,P53367 3 +E3-binding domain superfamily [IPR036625] 0.3721191680719568 0.0998924316479705 0.9204297249678228 1.0 0.9448470668402564 3 O00330,P11182 2 +SWIB/MDM2 domain superfamily [IPR036885] 0.3701517706576826 0.0970850732086317 0.9226588347144782 1.0 0.9456105470208084 3 Q96GM5,Q92925 2 +Ankyrin repeat-containing domain superfamily [IPR036770] 0.2940343977136041 0.0872097526791201 0.9305047873777544 1.0 0.9508134236102052 21 Q8IUH4,Q86XL3,Q15057,Q9H078 4 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.3605958403597603 0.0842321471886674 0.9328718592416988 1.0 0.951139305604248 3 O60884,Q96EY1 2 +HSP40/DnaJ peptide-binding [IPR008971] 0.3609001406469826 0.083323874188809 0.9335940174426164 1.0 0.951139305604248 6 Q9UBS4,O60884,Q9UDY4,Q96EY1,P25685 5 +Glutamine synthetase/guanido kinase, catalytic domain [IPR014746] 0.3642342655778176 0.0734098394745966 0.9414799879547284 1.0 0.9582256794400892 4 O75879,P12532 2 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.3104163670204265 0.0494203769780913 0.960584289521671 1.0 0.9726569595885112 8 P35637,Q01844 2 +Ribosomal protein L1-like [IPR023674] 0.3265879707701038 0.0484908784354153 0.9613250338457324 1.0 0.9726569595885112 3 O76021,Q9BYD6 2 +Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095] 0.3265879707701038 0.0484908784354153 0.9613250338457324 1.0 0.9726569595885112 3 O76021,Q9BYD6 2 +Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035] 0.2484541877459319 0.0121716759607959 0.9902886474613648 1.0 0.9990179303478998 3 Q8IVS2,Q8IY17 2 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6eff94f6b416a30da4662ebe89282f451306d944 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "AN1-like Zinc finger [IPR035896]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Actin-related protein 2/3 complex subunit 5 superfamily [IPR036743]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "Autophagy protein Atg5, UblA domain [IPR042527]", "Autophagy protein Atg5, helix rich domain [IPR042526]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Bcr-Abl oncoprotein oligomerisation domain superfamily [IPR036481]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CGI121/TPRKB superfamily [IPR036504]", "CH domain superfamily [IPR036872]", "CKK domain superfamily [IPR038209]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CYTH-like domain superfamily [IPR033469]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "Clp1, C-terminal domain superfamily [IPR038238]", "Clp1, N-terminal beta-sandwich domain superfamily [IPR038239]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Copper homeostasis (CutC) domain superfamily [IPR036822]", "Core-binding factor, beta subunit superfamily [IPR036552]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily [IPR023471]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DIX domain superfamily [IPR038207]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deltex, C-terminal domain superfamily [IPR039399]", "Deoxyhypusine synthase superfamily [IPR036982]", "DhaL domain superfamily [IPR036117]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 2 [IPR042264]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "EYA domain superfamily [IPR038102]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FAIM1 domain superfamily [IPR038513]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavin prenyltransferase-like [IPR036551]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GBBH-like, N-terminal domain superfamily [IPR038492]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP cyclohydrolase 1 type 2/Nif3 superfamily [IPR036069]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glu-tRNAGln amidotransferase superfamily, subunit C [IPR036113]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "HesB-like domain superfamily [IPR035903]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "Hypoxia-inducible factor 1-alpha inhibitor, domain II [IPR027452]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "Janus superfamily [IPR038596]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LOTUS-like domain [IPR041966]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "Mur ligase, C-terminal domain superfamily [IPR036615]", "Mur-like, catalytic domain superfamily [IPR036565]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NFRKB winged helix-like domain superfamily [IPR038106]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Notch-like domain superfamily [IPR035993]", "Nuclear hormone receptor-like domain superfamily [IPR035500]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRC-barrel-like superfamily [IPR011033]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "RecQ mediated genome instability protein, N-terminal, subdomain 2 [IPR042470]", "RecQ-mediated genome instability protein 1, N-terminal, subdomain 1 superfamily [IPR044881]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin kinase domain superfamily [IPR023465]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAS-6, N-terminal domain superfamily [IPR038558]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKA1 microtubule binding domain [IPR042031]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD MH1 domain superfamily [IPR036578]", "SMAD-like domain superfamily [IPR017855]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Set2 Rpb1 interacting domain superfamily [IPR038190]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Snake toxin-like superfamily [IPR045860]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "Sushi/SCR/CCP superfamily [IPR035976]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Taurine dioxygenase TauD-like superfamily [IPR042098]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonine synthase, N-terminal domain superfamily [IPR037158]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription factor EnY2 superfamily [IPR038212]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tryptophan synthase beta subunit-like PLP-dependent enzyme [IPR036052]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS28, C-terminal domain superfamily [IPR037206]", "VPS28, N-terminal domain superfamily [IPR038358]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WIBG, N-terminal domain superfamily [IPR036348]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "Wiscott-Aldrich syndrome protein, C-terminal [IPR011026]", "XPC-binding domain superfamily [IPR036353]", "XRCC4, N-terminal domain superfamily [IPR009089]", "XRCC4-like, N-terminal domain superfamily [IPR038051]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme, C-terminal subdomain [IPR044920]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "tRNAHis guanylyltransferase Thg1 superfamily [IPR038469]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AACS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP10", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP5M1", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARID4A", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL8B", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATRX", "ATXN10", "AURKA", "AURKB", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCKDHA", "BCKDK", "BCL2L12", "BCL2L13", "BCOR", "BCR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRIP1", "BROX", "BRPF3", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BZW1", "BZW2", "C1QBP", "C2CD5", "CAB39", "CACYBP", "CAD", "CADM1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP8", "CBFB", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDKN2A", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CEP350", "CEP97", "CERS2", "CERS5", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHML", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COG8", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COQ8A", "CORO1C", "CORO7", "COTL1", "COX11", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCUN1D1", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENND4C", "DENR", "DEPDC1B", "DERL1", "DERL2", "DFFA", "DFFB", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAIM", "FAM120A", "FAM120B", "FAM129B", "FAM234B", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FBL", "FBXL18", "FBXO21", "FBXO22", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FEM1B", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FOCAD", "FOXK1", "FOXRED1", "FPGS", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAN", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLPH3", "GOPC", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPRASP2", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H1", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUSB", "GXYLT1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS14", "INTS4", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JUP", "KANSL3", "KARS", "KAT7", "KCMF1", "KCTD10", "KCTD12", "KCTD15", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIN", "KLC1", "KLC2", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRR1", "KTI12", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRR1", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MALT1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED16", "MED25", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL7B", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLLT1", "MMAB", "MMS19", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NDC80", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF1", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEK9", "NELFE", "NENF", "NEO1", "NF1", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2C2AP", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN3", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHPT1", "PHRF1", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCD3", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP7", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RELA", "REPS1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RNASEH2A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRM1", "RRM2", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMD1", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF11", "SCAP", "SCCPDH", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC14L2", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SEL1L", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGSH", "SGTA", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPRH", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG5", "SMS", "SMU1", "SMYD3", "SNAP47", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STARD3", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN3", "STUB1", "STX10", "STX12", "STX4", "STX5", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT1A4", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "TAB1", "TAF2", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D24", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TEX10", "TFAM", "TFB1M", "TFCP2", "TFRC", "TGS1", "THADA", "THEM6", "THG1L", "THNSL1", "THOC1", "THOC3", "THOC6", "THOP1", "THTPA", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TLN1", "TMA16", "TMCO6", "TMED2", "TMED5", "TMED7", "TMEM115", "TMEM14C", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPRKB", "TPT1", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM56", "TRIO", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSTA3", "TTC1", "TTC19", "TTC27", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTI2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFM1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP32", "USP33", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIPAS39", "VIRMA", "VKORC1L1", "VPS11", "VPS16", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASL", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR41", "WDR43", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WDR92", "WFS1", "WIPI2", "WIZ", "WNK1", "WRAP53", "WRAP73", "WRN", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC4", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZDHHC13", "ZFAND1", "ZFR", "ZFYVE16", "ZNF277", "ZNF281", "ZNF512", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCD3", "ABCD4", "ABHD10", "ACAP2", "ACOT9", "ACP6", "ANKLE2", "AP1S1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "AP5M1", "ARCN1", "ARFIP1", "ARHGEF1", "ARPC4", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP7B", "BAIAP2", "BCL2L13", "BRD3", "BSDC1", "BSG", "CADM1", "CALU", "CANX", "CD47", "CERS2", "CERS5", "CETN2", "CHID1", "CKMT1A*", "CLCN3", "CLPB", "CNNM4", "COG8", "CPVL", "CTSA", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CYB5B", "CYP51A1", "DBT", "DERL1", "DERL2", "DHCR24", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DSC3", "ECE1", "EFCAB14", "EHD4", "EPHX1", "EPS15L1", "ERLIN1", "EWSR1", "EXOC7", "EXOC8", "FADS2", "FAR1", "FAR2", "FCGRT", "FKBP14", "FKBP7", "FLOT1", "FLOT2", "FUS", "GAA", "GALNT1", "GALNT4", "GATB", "GBA", "GGCX", "GINS2", "GLB1", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAO1", "GNG12", "GPD1L", "GUSB", "HADH", "HADHA", "HDGFL2", "HDHD5", "HLA-B", "HLA-C", "HMOX2", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "IBA57", "IMP3", "ITGA6", "KDSR", "LDAH", "LEMD3", "LETM1", "LMNA", "LMNB1", "LPCAT1", "LTA4H", "MAD2L1", "MAPRE2", "MCAT", "MFSD10", "MFSD14B", "MFSD8", "MGME1", "MGST2", "MIPEP", "MOSPD2", "MRPL1", "MRPL13", "MRPL14", "MRPL19", "MRPL2", "MRPL24", "MRPS11", "MRPS7", "MTCH1", "MTCH2", "MUT", "NAGLU", "NAP1L4", "NDUFA9", "NIP7", "NLN", "NNT", "NOP58", "NPTN", "NSDHL", "NT5C3A", "NT5C3B", "NT5DC2", "NUCB1", "NUCB2", "OSBPL9", "PCYOX1", "PDE6D", "PDHX", "PDPR", "PECR", "PGRMC1", "PGRMC2", "PHB2", "PIR", "PLA2G15", "PMPCA", "PNKP", "PNPLA6", "POLDIP2", "PPT1", "PPT2", "PRCP", "PRPF3", "PRPF31", "PRPF40A", "PSME2", "PSME3", "PTGR2", "PTPN9", "PTPRF", "PTRH2", "RAD23B", "RCN2", "RDH11", "RDH13", "RDX", "RETSAT", "RHBDD2", "RPL10", "RPL15", "RPL18", "RPL21", "RPL27A", "RPL36A", "RPL37A", "RPL6", "RPL7", "RPL8", "RPP25L", "RPS9", "RSL1D1", "RTN4IP1", "SCFD1", "SCFD2", "SCPEP1", "SDF4", "SDR39U1", "SEC14L2", "SEC22B", "SET", "SIRT2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC3A2", "SMARCA5", "SMARCD1", "SMARCD2", "SQLE", "SRPRA", "SRRM1", "STARD3", "STOM", "STX10", "STX12", "STX4", "STX7", "STXBP3", "SV2A", "SYAP1", "TAP1", "TAP2", "TIMM10B", "TIMM44", "TMED2", "TMPO", "TOR1AIP1", "TRAP1", "TRAPPC4", "TRIO", "TSPAN3", "UGCG", "UNC119", "UQCRC2", "UXS1", "VAMP7", "VAPA", "VAT1", "VDAC1", "VDAC2", "VDAC3", "VIPAS39", "VPS33A", "VPS33B", "VPS51", "YARS2", "YEATS4", "YKT6", "YME1L1", "ZADH2", "ZDHHC13"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..172c84b5911a1c0e617374f561938271a1bd3cc8 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5743142839b5887f5b53b460be3c1214306c5402bc6408bf13d5507bcf525942 +size 79687 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0aeae9a294e44bbf356974ecb54f5643d0b87ade --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +P-type ATPase, phosphorylation site [IPR018303] 3 8 2.0539743393309315 0.0399781753779207 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0546082347726425 1.0 1.0 0.0145721558996701 0.0193421266882966 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..862e41a6467ab77ab016c24284b4cd46142ecbeb --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 3.25 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1b3adef6d470e5d551f501e0b90e6053f4d5ee49 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b8d23eade7c06813f8abd5093a673e6de932a18c --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.7663249917016802 2.0539743393309315 0.0399781753779207 0.1505762012507736 0.0533042338372276 8 Q9HD20,P16615,P35670 3 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a56232b6e5c56c3804a853fd04c2cccbe88deef2 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP7B", "EIF5A", "FASN", "LDLR", "NOTCH2", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP2A2", "ATP7B"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c594832e19b99c08eca415368adb31a34d1ded74 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cb5cfd8ea4879cee30faec7d55725e6eac2583551e4f28c1212648a2784b69d3 +size 191120 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..585c2f35871e09b78febdd7e19c704472ab15d46 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c1f27b3402152a29175ed6de58bd5aecff968b33201d94db151c401b24f363a2 +size 150346 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..61908c8699dc717f32a6dc53f68bb85f0be2095e --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0eaa687991c2dbefdb59c99f524270a789bbc14f5e867a322ab8c5ea9135fa45 +size 93998 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9a38f958b4ce11ec0418155f77eb6842e64dae28 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 19 23 3.4940938274724385 0.0004756738101701 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 5.660513393058556e-10 1.0 0.0053755248402168 7.339182273039057e-10 3.341464831402234e-13 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9905caee78e15993eab1cf767851bd80cec80cd2 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 81, + "title": "Average number of proteins per term", + "value": 5.827160493827161 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..75fc7b3fcc4659d3adbf8631b24264a0fe8e942f --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dead7513f89457dd70a0f385a62a4cff3a5e7c13 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.807859110244296 3.4940938274724385 0.0004756738101701 0.0378055764810431 0.0029638137402906 23 Q9NZJ7,P53007,Q9HC21,Q86VD7,Q6NUK1,P12235,P05141,Q6KCM7,Q70HW3,O43772,Q9BSK2,Q8TBP6,Q02978,Q9UJS0,O43808,Q9H2D1,P12236,Q9UBX3,Q9Y6C9 19 +Mbt repeat [IPR004092] 0.4922731104242751 0.5959889158019014 0.5511826314890516 1.0 0.620080460425183 2 Q9UQR0 1 +Pentatricopeptide repeat [IPR002885] 0.5116671352263052 0.4289702676195008 0.6679448622612458 1.0 0.7311288357183907 4 Q96EY7,O75127,Q92552 3 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a71f9526c8b7c14b2e1888fe374830dd74aceed4 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "MORN motif [IPR003409]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACAP2", "ACTN1", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC6", "ARMCX3", "ARPC1A", "ARPC1B", "ARVCF", "ASPH", "BCOR", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CD320", "CDC16", "CDC23", "CDC27", "CDC40", "CEP97", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "CNOT10", "COA7", "COLEC12", "COPA", "COPB2", "CORO1C", "CORO7", "CRNKL1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "CTTNBP2", "DCAF13", "DCAF7", "DCAF8", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FEM1B", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "GAN", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HTT", "HUWE1", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "ITGA6", "JUP", "KAT7", "KDELC1", "KDELC2", "KDM2A", "KEAP1", "KLC1", "KLC2", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "L3MBTL3", "LARP1", "LASP1", "LDLR", "LLGL1", "LRBA", "LRCH2", "LRPPRC", "LRR1", "LRRC1", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MED16", "MIOS", "MKI67", "MKLN1", "MPDU1", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NOL10", "NOP2", "NOP9", "NOTCH2", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "OSBPL1A", "P4HA1", "P4HA2", "PAAF1", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "PLXNA1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABGGTA", "RACK1", "RAE1", "RAI14", "RANBP2", "RANBP6", "RANGAP1", "RAP1GDS1", "RBBP5", "RBBP7", "RCC1", "RCC2", "RNH1", "RPAP3", "RPTOR", "RRP9", "RSU1", "SART3", "SCAP", "SCML2", "SCRIB", "SEC13", "SEC31A", "SEH1L", "SEL1L", "SETD7", "SGTA", "SHCBP1", "SHOC2", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STRN3", "STUB1", "SUGT1", "SYNE1", "SYNE2", "TAGLN2", "TBL1XR1", "TBL2", "TBL3", "TEX10", "TGFBRAP1", "THOC3", "THOC6", "TLE3", "TMCO6", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TRIO", "TTC1", "TTC19", "TTC27", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS11", "VPS18", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR41", "WDR43", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WDR92", "WFS1", "WIPI2", "WRAP53", "WRAP73", "XAB2", "XIAP", "XPO1", "YTHDC2", "ZC3H7B", "ZDHHC13"], "leading_proteins": ["MRPS27", "MTCH1", "MTCH2", "PTCD1", "PTCD3", "SCML2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..80ebe527ff3fd5c0d6ee2f51690514e52c5193eb --- /dev/null +++ b/msigdb_gobp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transmembrane transport", "1": "Ion transmembrane transport", "2": "Mitochondrion organization", "3": "Membrane organization", "4": "Ion transport", "5": "Anion transport", "6": "Membrane lipid metabolic process", "7": "Mitochondrial transport", "8": "Lipid metabolic process", "9": "Anion transmembrane transport"} \ No newline at end of file diff --git a/msigdb_gobp/advanced/plot_0.png b/msigdb_gobp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..9919392cbad823ae4e3574663a24fac6197a8cbb --- /dev/null +++ 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4.0619669904912925 1.6676089351046874 0.3062687621764124 2.116796077029668e-08 0.0006106679300335 1.2205770519728212e-06 1.0508155306829796e-08 2.244354142747463e-09 +Mitochondrial respiratory chain complex assembly 26 43 3.4682068198157547 0.0005239438834927 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 0.0001687778645134 0.0083999939712921 2.235155371602687e-05 5.61015778295741e-05 4.5926675189420374e-08 +Organophosphate ester transport 17 32 3.429840097399645 0.0006039370436221 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 8.085355684432827e-06 0.0512049491784678 0.0064708018379125 1.6131627677639663e-05 2.467960480807351e-08 +Steroid biosynthetic process 22 52 3.33316198368226 0.0008586493552968 11.728155339805824 44.80825242718446 0.9874364787035632 0.3935759881445143 5.016369659264937 4.35272817633461 1.2862817592315925 0.3680333006848349 8.150111852304989e-07 0.0734859631012788 0.0002951956690704 4.368865843402089e-07 6.728681286146038e-07 +Cellular respiration 31 103 3.249455919819167 0.0011562599675889 27.975728155339805 102.1019417475728 0.3887198796668061 0.4496840882999475 12.70690482749566 7.191843824002275 1.6294784865611704 0.3894421445164553 0.0004260953460236 0.0016936885573156 0.0003962033558661 4.267247003461898e-05 2.4292532601995204e-08 +Sphingolipid biosynthetic process 14 21 3.2382525048964186 0.0012026431658587 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 6.488388230624962e-05 0.0301263989446325 0.0022607128548013 1.0662927613746742e-06 3.300910550529006e-06 +Lytic vacuole organization 11 27 3.2363079041940748 0.0012108669504873 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 8.002197476866621e-06 0.0310751174278923 0.0024049294720084 1.0599407942085492e-05 2.2501436638464372e-05 +Cellular lipid metabolic process 79 229 3.234726278625156 0.0012175939731509 55.06310679611651 205.83495145631068 0.2402431693065998 0.4937242414097398 20.280338607556292 23.717838556123585 1.6370289909336062 0.4061780961812439 8.653561776151944e-08 0.1358079042017378 0.0012454678887019 1.499891652840972e-09 1.2879794975561416e-14 +Alcohol metabolic process 30 89 3.221690944795604 0.0012743651566817 19.300970873786408 81.99029126213593 1.0392616248309592 0.3936245775900834 6.9548962308345 7.403089286448431 1.208378917036781 0.3759976884392474 3.125437926610432e-06 0.0026287419261841 3.96212897674274e-06 2.286615845751059e-06 7.696205903650618e-07 +Mitochondrial membrane organization 21 48 3.217301617615062 0.0012940248250343 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 0.2302575849664885 0.0721769910274738 0.0617759235487824 0.0077379412599993 5.730636576295476e-07 +Carbohydrate derivative transport 14 19 3.2127614031855485 0.0013146545373292 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 1.229355546992287e-05 0.1918484459181316 0.3534667347825532 1.073457119943074e-05 1.757016595920162e-09 +Endomembrane system organization 56 188 3.2110590794063705 0.0013224674325245 47.08980582524272 169.73058252427185 0.8987911429216844 0.5600148744834964 15.914797198368843 20.49740065572335 1.4161383035869868 0.4170367608227654 0.0071040198953975 0.1018980887909014 0.3002235444234402 0.0003507388804179 9.601688752691703e-09 +Organic acid transport 32 53 3.181819890931599 0.0014635280086729 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.0312669234281056 1.0 0.1386755800442893 0.1075073392078498 0.000295286471728 +Establishment of protein localization to membrane 34 93 3.1669218735148523 0.0015406170211265 23.133495145631063 87.3616504854369 1.231448880072231 0.4195243824117992 8.397245527204214 9.510228790351464 1.3947369206386535 0.4065372973031916 0.0028080879597059 0.0141871701647657 0.0432382817184384 0.0003548191684032 0.0003175265153851 +Protein insertion into membrane 15 27 3.1554512034498368 0.0016025006960347 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 0.0576324875298074 0.0016372603162341 0.0121545348373523 0.0001848356829715 3.788623596856414e-06 +Oxidative phosphorylation 22 61 3.155036678631515 0.0016047792918798 18.140776699029125 60.61893203883495 0.8137621380364766 0.3661293054253088 7.750013302753429 5.582386553809936 1.7413544544034578 0.3762713520958283 0.0002105945270165 0.0002063963467492 0.0001249069906169 0.0005203901982914 4.1508419418248393e-08 +Endoplasmic reticulum organization 19 44 3.1507592846544275 0.0016284664213706 14.91747572815534 43.67718446601942 1.1418424810127707 0.3725584991544436 6.208589840117394 4.768440325801463 1.6823827875834556 0.3705219831566139 0.0003251184098037 0.005100197971692 0.0056446365440786 1.1375239350593556e-05 8.099370540254251e-08 +Alcohol biosynthetic process 14 40 3.143046888780569 0.0016719905454427 9.344660194174756 36.09466019417476 1.0726679306851277 0.3539682718575088 3.792896481514287 3.1078151772256564 1.1587776417647702 0.3419459456532639 2.566926569563043e-06 0.007660842490478 1.7937638412355432e-05 1.012639025765744e-06 3.713295377242547e-06 +Ceramide metabolic process 13 22 3.142920925839129 0.0016727102046376 8.191747572815533 19.060679611650485 1.0632949889077032 0.1865092544415649 3.2982239784478966 2.5917545738626013 1.8901201919357584 0.2494992632187684 5.176335998724231e-05 0.0282648516431577 0.0019903837628301 5.428289418428127e-05 1.2971465827819926e-05 +Secondary alcohol metabolic process 22 48 3.122387544360022 0.001793906244397 12.097087378640778 42.24514563106796 1.5200936296432006 0.2566232504859334 4.463475425703621 3.883072640851752 1.3223501002339118 0.3210874999447533 2.769500065025596e-08 0.0006668220639634 1.4593991767804417e-06 1.4340380476722924e-08 3.4712654380006566e-09 +Lipid localization 26 81 3.117561154512364 0.0018235410986662 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 6.206477781488383e-06 0.000495119732067 4.136714325753095e-05 7.220354414475536e-05 0.0001542939405434 +Inner mitochondrial membrane organization 14 20 3.030613384108351 0.0024405753280853 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 0.475551772355075 1.0 0.2957660567507726 0.0110616415512106 8.185264203324944e-08 +Protein targeting to mitochondrion 20 50 3.024205361788374 0.0024928715868151 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 0.00409108305122 0.0006962305099777 0.0094204958227649 0.0002301188570363 1.684086605424508e-05 +Protein transmembrane transport 8 25 2.9990423758691582 0.002708296356211 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 0.0021262505871442 9.836147142209114e-05 0.0015183657514178 0.0082073559004823 0.0008502005655503 +Aerobic respiration 26 87 2.989806074476921 0.0027915461412553 23.075242718446603 86.43446601941747 0.4685851027775424 0.4381258038241513 10.546552774557412 6.275478278783705 1.570513830163352 0.3792860784147517 0.0017197184279804 0.0007829726350015 0.0007329013002734 0.0001026181138345 1.4028181249975806e-07 +Glycoprotein biosynthetic process 26 56 2.982570355489136 0.00285838942972 16.72087378640777 51.87378640776699 1.042113998842759 0.381483262234126 6.756316800759528 8.908847583990125 1.5232206853916193 0.3819786061588057 0.4162611845478006 1.0 0.8370580570865493 0.0151505087717804 0.0099844410092999 +Protein localization to mitochondrion 24 61 2.98160545421937 0.0028674127340653 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 0.0026158027188632 0.0014960741415954 0.0187923503468816 4.8680044939330585e-05 3.41287560073493e-06 +Nucleotide transport 12 16 2.9676365113850647 0.0030009898871419 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 4.198132317436559e-06 1.0 0.2182850433665622 1.741035453580761e-06 3.6539675538520716e-11 +Monovalent inorganic cation homeostasis 11 33 2.9492518911943777 0.0031854423007653 9.014563106796116 27.87378640776699 1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 0.0372032513718843 0.2871482614220745 0.1504925922074863 0.0294136582376105 0.002441731581876 +Localization within membrane 62 201 2.940971902538513 0.0032718421043556 43.83252427184466 179.48543689320388 0.7329824809593914 0.5973922945503244 12.803162929787796 21.32668417309247 1.133148805830878 0.4087008058998355 0.019560097557335 0.0696635094807577 0.1682880062967132 0.0004724911263453 0.0002502945082934 +Atp metabolic process 30 112 2.9341185947499437 0.0033449637356803 25.97087378640777 107.69417475728156 0.2650120939459569 0.5409439866831242 10.270805368899644 8.059768543771504 1.2580915670575048 0.3757529915372982 7.207149757488109e-05 0.0003869492902001 0.0001602494927387 0.0004989788846788 2.816373082286212e-07 +Nadh dehydrogenase complex assembly 18 31 2.892957210871977 0.0038163328446987 9.266990291262136 26.96359223300971 1.1245271541492263 0.3013677937017552 4.122702675359976 4.029157649894909 1.4460543016521823 0.3224564676521605 0.0029353788574153 0.0282648516431577 0.0019903837628301 0.0003740765768456 2.180950645403597e-06 +Sterol biosynthetic process 14 30 2.8810785557194074 0.0039631685080405 7.281553398058253 24.52912621359223 1.190088798384403 0.3136799329736269 3.292879861326439 2.61838648411319 1.1232845583768152 0.3105481837594456 1.4236595390409623e-05 0.0197081838633031 0.0009655190728592 1.2781982538308898e-06 1.949190825949702e-07 +Proton transmembrane transport 20 41 2.875088594572748 0.0040391414467897 14.28640776699029 43.01699029126213 0.7821394801431882 0.3918912894345224 6.076814900000799 3.1076483585332 1.5710697941383835 0.3739424994204808 0.0793647209860792 0.0091798295241952 0.0587257861189147 0.0241780852017221 3.782059174825789e-05 +Respiratory electron transport chain 19 52 2.85371379547423 0.0043211441306012 15.4126213592233 50.33495145631068 0.497076868891423 0.4388579749555677 7.129498131980449 4.223655269147207 1.4894225458303931 0.3736358875877055 0.0013285554982852 0.0097225551321659 0.0020730092274054 0.0004431170123273 1.1355904492385225e-07 +Glycoprotein metabolic process 28 63 2.830340954420246 0.0046498423014802 18.59223300970874 59.577669902912625 0.8707431654759812 0.409720724299967 7.543964208858723 9.989377193127202 1.488085349392555 0.3835029669336279 0.550552899141477 1.0 0.8849091002675707 0.0430865246961953 0.0448089264787276 +Cellular monovalent inorganic cation homeostasis 11 29 2.8230568329721195 0.0047568138499767 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 0.0208795136359623 0.2462339839987873 0.1124462638013597 0.0146138032070347 0.0005927562281282 +Atp synthesis coupled electron transport 14 39 2.81627982028574 0.0048583331460254 11.567961165048544 37.61407766990291 0.6403585631460136 0.4181082416574377 5.189865284224125 3.9859091462453993 1.417482213086961 0.3703097362636519 0.0022330615788114 0.0054839454740183 0.0061870399193519 0.0024540045177978 3.611942513843052e-06 +Liposaccharide metabolic process 8 18 2.803834805837435 0.0050498771322768 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 0.0783748786893149 1.0 0.4231831300186898 0.0119153698475834 0.0016516323552223 +Inorganic anion transport 13 29 2.790523693993732 0.0052622848430994 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 0.0001775346937146 0.0401297445487486 0.000465252968756 3.374735925264517e-05 2.028925780732652e-05 +Regulation of ph 10 24 2.751080811439474 0.0059398988046106 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 0.0121991568151097 0.214048603403005 0.0859380278487259 0.0075761723461217 0.0007365436562396 +Regulation of cellular ph 10 24 2.751080811439474 0.0059398988046106 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 0.0099347327982874 0.2030241760524146 0.0775893010395362 0.0058863909817598 0.000467430048284 +Metal ion transport 23 115 2.732917174511362 0.0062776116338512 24.868932038834952 99.21116504854368 0.6600358663497399 0.5322554902435589 9.162889792248723 11.473971032908404 1.1670714049066973 0.3920241658733104 0.0027966713505254 0.0755590703510497 0.2301740972050841 0.0015937700256962 0.0051558430314365 +Amino acid transmembrane transport 13 17 2.6921927227262468 0.0070983913180762 6.213592233009709 14.228155339805824 0.7890307267204019 0.3318923540291705 3.493823914060917 1.9561661273054285 1.3497309258640615 0.3227865040448734 0.194495261060371 1.0 0.3595817292068155 0.3072275582187334 0.0241162406389391 +Intracellular protein transmembrane transport 6 22 2.6879584276856803 0.007189034628525 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.0073675752544559 0.0011373944560536 0.0086239941031961 0.0215529467605083 0.0052617874550274 +Organic hydroxy compound biosynthetic process 22 60 2.6876229184712086 0.0071962610845983 12.42233009708738 52.37135922330097 0.7934054609743442 0.424605725297311 4.713262264354627 5.1877801804871915 1.1130427360157376 0.3580104692277669 8.66205678084197e-05 0.022283874858167 0.0002270765112582 1.3317436915415276e-05 0.000171249908799 +Organic hydroxy compound metabolic process 36 121 2.6819083137217623 0.0073203519771367 24.233009708737864 110.8883495145631 0.5334558429683288 0.4627633417898757 8.017219191403747 10.01417249072314 1.2419084217888356 0.3713800795527268 3.5675974173097015e-05 0.0099627040770777 7.641160845574992e-05 5.212657437625168e-05 4.904535116120417e-05 +Ceramide biosynthetic process 9 14 2.6804205949480946 0.0073529707182453 4.033980582524272 10.24757281553398 1.048715387316577 0.2344614502118888 2.237979905601341 2.0281678881596505 1.4071730245015133 0.2685344998940062 0.0003088658659614 0.1495431827221669 0.0042562107320329 0.0013109740347349 0.0002002807179905 +Nucleotide transmembrane transport 8 11 2.67700619113299 0.0074283262325229 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 0.0001327727267659 1.0 0.1405588989726414 2.5486927073579494e-05 1.0762089436652486e-08 +Regulation of mitochondrion organization 13 46 2.674578210411016 0.007482332139109 12.08980582524272 45.08252427184466 0.8217268052205459 0.4563186211764868 4.409741308614158 5.146210353910189 1.120993905462196 0.3778427085178187 0.0030520446790819 0.4028860511966072 0.2809776465336315 0.0163896478998186 0.0008406814351393 +Regulation of lipid biosynthetic process 11 30 2.652016956174333 0.0080012523627954 5.211165048543689 26.83009708737864 -0.4437734844517033 0.3480223204908034 2.903224120378468 2.997615069864524 1.2473712283529377 0.2827476345582833 0.0195878096988954 0.0644911739814566 0.0101771345765348 0.0054641541127343 0.0011900381337182 +Glycosylation 21 50 2.6442210016211605 0.0081879176380672 13.33495145631068 45.42718446601942 0.831363055351092 0.4028474919440285 5.5712021107485015 7.578523489860055 1.3433056638769032 0.3649215649501745 0.1485938320217766 1.0 0.4528097805573071 0.0052211765203396 0.090103291345979 +Electron transport chain 22 71 2.6382414939770573 0.0083337211356167 19.550970873786408 67.77184466019418 0.3712062453977176 0.4872800905659868 8.486701420407794 5.37626783377928 1.3790913022045077 0.3735693075609537 0.0078431047378731 0.0227297277739018 0.0080532386653731 0.0002963890379893 2.812012082471621e-07 +Protein localization to endoplasmic reticulum 11 35 2.597568781319121 0.0093886315046975 9.50242718446602 34.50485436893204 0.9935384348474128 0.428255638055916 4.399083524593319 2.6617527855555916 1.1934894982037212 0.3717243536861919 0.0752344556072313 0.0282648516431577 0.1004140149250811 0.0459551502585406 1.2971465827819926e-05 +Atp transport 7 8 2.5772431016777246 0.0099591880559253 3.4805825242718447 6.233009708737864 0.5838786306840471 0.3211615036091749 1.83337760624298 0.8807971179633459 1.3636108978108328 0.3170401972517012 0.0098489116445482 1.0 1.0 0.0009978388997276 2.3225344425372948e-10 +Purine nucleotide transport 9 13 2.5671812257054247 0.0102529011839191 4.970873786407767 10.817961165048544 0.961055494000064 0.2880106547862709 2.8308505383502496 1.988649275322177 1.3314072021441097 0.3042395363852717 0.0046437067491223 1.0 1.0 0.0011116174795585 7.180176827125465e-09 +Energy derivation by oxidation of organic compounds 33 125 2.5650625401230607 0.0103157209707025 30.652912621359224 122.18932038834951 0.2541815110246533 0.5071130371174295 12.61138398748304 8.311769788309597 1.4201467433346076 0.3884313364311733 0.0032475670624753 0.0050059471083382 0.0020227895615157 0.0006760420909025 5.867801953803012e-07 +Endoplasmic reticulum membrane organization 6 9 2.5596561524109207 0.0104775773118992 3.5679611650485437 8.12621359223301 0.656874598832497 0.271683145803182 1.813579499342004 1.2879547393790816 1.532817064292788 0.2945772195616556 0.0012731085823663 1.0 0.1157837219692003 0.0001869772650567 7.565932780436378e-07 +Amino acid transport 16 26 2.540484685041639 0.0110698941700704 7.771844660194175 19.75 0.8410032854505353 0.3449280742441291 4.117377746800764 3.003739578643708 1.287399790463736 0.3206698223659758 0.3349491447838933 1.0 0.4805273996536341 0.4902724480503764 0.0171267176251654 +Protein insertion into er membrane 8 13 2.538007185427654 0.011148569543641 4.451456310679611 12.691747572815531 0.9645901040516046 0.3077872373135509 2.16101217194965 1.431147904526304 1.1733171268605926 0.305304417896891 0.0546082347726425 0.0045302650272878 0.0179304062363867 0.0145721558996701 5.148232495325733e-05 +Lipoprotein metabolic process 10 25 2.516939686388397 0.0118379091896787 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.0034443276456963 0.3258864463602873 0.0459278250864885 0.0039874357255632 0.0024004575856903 +Glycerolipid biosynthetic process 25 52 2.4996880364848675 0.0124302712976458 13.466019417475728 44.71844660194175 0.9430872689732808 0.3767257192898063 6.88753698417372 8.249645447783736 1.3199493331746477 0.3584243730449019 0.0373243998413282 0.2028967221549326 0.2427763389694352 0.0285638176541083 0.0062525456976727 +Glycerophospholipid biosynthetic process 22 46 2.4921169360400657 0.012698422291586 12.407766990291265 39.55339805825243 0.6228968293784067 0.4586227574071144 6.110530292090928 7.803693618041913 1.233194093755117 0.3515784330467275 0.1432452587899048 1.0 0.7825080944884357 0.1804903126038815 0.0218451768167398 +Response to endoplasmic reticulum stress 31 86 2.4910168845619247 0.0127378066338044 20.766990291262136 81.87135922330097 0.3895578367391949 0.6272162805638101 7.658618957730667 6.11384352257493 0.925049322897134 0.3624458148773257 0.8639335808251822 1.0 0.8520395930000729 0.0081430832193739 3.1271166482616e-05 +Hormone metabolic process 11 31 2.4686946148938747 0.0135606891075383 8.95631067961165 28.65776699029126 1.130508313948193 0.2963365150575847 3.9674689274001818 2.5345884681715156 1.346801337886388 0.3240077568826507 0.0014114385632497 0.3625618934304275 0.0633283793885551 0.0004785207866448 0.0007167261348617 +L amino acid transport 10 13 2.463722384060902 0.0137502566867222 5.114077669902913 11.91504854368932 0.7755289387861473 0.3283794523692901 2.998235059113201 1.3256494094845783 1.3058948249973923 0.3189923022900864 0.1161779578639089 1.0 0.275422289319612 0.1927267877862009 0.0220710469799609 +Regulation of lipid metabolic process 18 60 2.463488111565578 0.0137592458358564 12.599514563106796 52.890776699029125 0.2189053156740071 0.4007176079141414 5.562295027948738 7.005213895866115 1.3822804240908182 0.3523493088444139 0.0004658733721466 0.057547361640351 0.0340548154582183 0.0006209243046298 0.0003321987617008 +Regulation of steroid biosynthetic process 7 12 2.46248833639835 0.013797666052016 3.186893203883495 10.259708737864075 0.6168896095149775 0.3174156062343823 1.783561142158544 1.373475469974866 1.265753415239616 0.2847701277650337 0.139376276923864 1.0 0.3024208907496342 0.0606393891427922 0.0019543902326982 +Vitamin transport 6 9 2.4601739712476225 0.0138869681470112 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 4.7155433495924e-05 0.1050728360238821 0.0211645746663273 0.0002123083759959 9.607383470425282e-05 +Membrane lipid catabolic process 5 12 2.438801954378446 0.0147360417568578 5.854368932038835 11.361650485436892 0.500872843713425 0.1363587272813367 1.9603237645724247 0.9867004907377388 2.113024793917032 0.2289617793743788 0.0003348720906127 1.0 0.0008209706516698 0.0011116174795585 0.0002599861644489 +Protein targeting to membrane 13 42 2.4053644596696997 0.016156343961619 9.03640776699029 34.86407766990291 0.8678999397376299 0.4369909067843477 3.776027437978551 4.807050937156168 0.9685770296783628 0.3476738150633759 0.0048236448060394 0.0657516499382864 0.0542893861193368 0.0209747116267893 0.0117444524522708 +Phospholipid metabolic process 31 83 2.392084623595669 0.016752979205264 18.805825242718445 74.80339805825243 -0.0109191555178773 0.4658808189502442 8.677118948764809 11.032066592781655 1.2956045948013235 0.3559409313369701 0.0045377797738957 0.0290475413374261 0.0325013459527067 0.0075537416698484 0.002584190742276 +Diol metabolic process 3 8 2.391638544642613 0.0167733520674218 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0023996235659409 0.0713092569444504 0.0004144497686355 0.0004499506622467 0.0060423314672148 +Diol biosynthetic process 3 8 2.391638544642613 0.0167733520674218 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0012731085823663 0.0583291306653072 0.0002160518736796 0.0001869772650567 0.0026623648375823 +Phosphatidylglycerol metabolic process 7 10 2.3907384555662445 0.0168145262456265 3.7572815533980584 10.78640776699029 0.7074456860764219 0.3298030384317407 2.521619218643941 1.658461595229837 1.2128783939533223 0.2875854965146425 0.0087962585732332 0.1092078710908161 0.0228657680446322 0.0026445688691081 0.0009678132279787 +Protein transmembrane import into intracellular organelle 5 13 2.390411214968096 0.016829517699866 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0145822304975559 0.0083336110644575 0.0321664764057317 0.0334599986224988 0.0026462677024259 +Cytochrome complex assembly 8 12 2.3861348434952 0.0170265067891328 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 0.0204436144926609 0.145591480261755 0.0039178748513905 0.0082083083177425 0.0009836297221044 +Negative regulation of secretion 6 23 2.3848255299881616 0.0170872229169627 4.148058252427185 18.021844660194176 0.8973427539161298 0.3984823243406039 2.1406652437798495 2.8560969523306214 0.8942114095598058 0.3123655158346225 0.0256998154210269 0.2601211086473298 0.1248310733848052 0.0682124865403787 0.0356701263332718 +Calcium ion import 3 16 2.382219426191732 0.017208640032942 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 0.0255704895202036 0.0125009202076431 0.0472129003194087 0.0110616415512106 0.0307651975348569 +Glycerophospholipid metabolic process 30 62 2.37715067590259 0.0174469596598374 14.597087378640778 57.060679611650485 -0.0519222534779674 0.4286122989812534 8.002292830543196 9.368077769293231 1.3877870839733877 0.3500560744701435 0.0263577340671723 0.2454389769276036 0.3066921634194756 0.0250469716227983 0.0048356911536414 +Vacuole organization 17 62 2.374855708757901 0.0175558115212417 14.220873786407768 51.74514563106796 0.8524122478550634 0.3147425083910056 5.370022076358251 7.439112114793103 1.7567175511320523 0.3563110134355993 0.005384572741966 0.1598369683375962 0.0583510223483309 0.0038242286566039 0.0075800784520749 +Glycolipid biosynthetic process 5 10 2.3693740168401853 0.0178182243787918 3.3009708737864076 8.701456310679612 0.8778541677747596 0.2891249509557468 2.0940737065519093 2.1465026455410077 1.206628042966233 0.2848826766737565 0.127650627038734 1.0 1.0 0.010048900874146 0.0068057981890614 +Glycosphingolipid metabolic process 4 9 2.363429388538985 0.0181066768117768 4.764563106796117 9.184466019417476 0.4485135251287195 0.1553285492394019 1.7516723087054535 1.7320372023153958 1.93068386398988 0.2217231968869004 0.1105465258987554 1.0 0.2685126379615966 0.0427102581002517 0.0195746287107578 +Regulation of steroid metabolic process 8 18 2.3627081751213 0.0181419490714023 4.334951456310679 14.769417475728156 0.4748357054552781 0.3599056508632772 2.2294240946396933 1.955260926764874 1.2378399088740557 0.2930403635554361 0.06041412002344 0.214048603403005 0.0859380278487259 0.0344783823248686 0.0007365436562396 +Protein import into mitochondrial matrix 4 9 2.3608707873578183 0.0182320819186576 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0019745890336275 0.0021019285577768 0.0085055091795532 0.004864195908138 0.0005047578024907 +Cristae formation 6 9 2.347508780140967 0.0188994277139462 4.740291262135922 8.861650485436893 0.8982766043222677 0.3392698633906088 2.216011442046921 0.6593503673812457 1.2485531022675598 0.3418736408093433 1.0 1.0 1.0 0.2857421618237076 2.5790420180080805e-05 +Porphyrin containing compound metabolic process 5 18 2.340556542458313 0.0192550225549295 4.91747572815534 16.531553398058254 1.0269348271542438 0.279733852070357 2.276512713100022 2.089380108414912 1.2578863722796805 0.2914421038569487 0.0029585779551093 0.1495431827221669 0.0426903814680922 0.0001530781343508 0.0059055963574577 +Regulation of calcium ion import 1 6 2.339681187620158 0.0193002073199286 0.9174757281553398 4.213592233009709 0.9090342411122554 0.2914151900098607 1.055722012585453 0.969440689883507 1.1191898387469632 0.2647111586612949 0.0339972376759384 0.0027065615852008 0.0108829135912838 0.0603828760130106 0.1955185018186248 +Regulation of lysosomal lumen ph 3 6 2.319593713717281 0.0203628662420423 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.0001009347750178 0.0670021260054199 0.0085055091795532 0.000343834728447 0.0047081007231922 +Regulation of atp metabolic process 4 26 2.3125809022382264 0.0207456925367859 5.475728155339806 26.274271844660195 0.334640781503248 0.5621665759070464 3.158728576082886 2.9845912055027837 0.8610357625710494 0.3157017370833172 0.0197691529689287 0.0310751174278923 0.0188000817445546 0.0136728919383771 0.1604828788989237 +Tetrapyrrole metabolic process 5 22 2.302102527173661 0.0213293909469887 5.652912621359223 19.283980582524272 1.0342508202848784 0.290677507336007 2.6828141040028877 2.549402305664568 1.2308389507353266 0.2976223887279709 0.0068025853341391 0.1843129003022452 0.0643053609617777 0.0005570332976579 0.0046303272101973 +Sulfur compound transport 3 10 2.2937223580894357 0.0218064516513933 3.504854368932039 9.429611650485436 1.339223354728307 0.2167503093092372 2.046184165461596 2.1092484385198076 1.0728301411615704 0.2604171804663498 0.002374895513008 1.0 0.2685126379615966 0.0073773967902559 0.0717785358518721 +Regulation of toll like receptor signaling pathway 6 11 2.2913231734380224 0.0219447292961221 2.587378640776699 9.50485436893204 0.9772136844316576 0.3297728067967737 1.666236944633112 1.8466647258935645 0.9012634534298872 0.2761306672489575 0.1634663128754785 1.0 1.0 0.077109656392341 0.0494824412948022 +Reactive nitrogen species metabolic process 3 17 2.268023223327286 0.0233277912546894 3.9805825242718447 16.550970873786408 0.5187061899010498 0.4616229774504417 2.0608725766457097 1.6501909360329357 0.9419567550357958 0.306935586730602 0.1757749360267854 0.1843129003022452 0.3410628818122171 0.0860045321118681 0.1594896243783859 +Sensory perception of light stimulus 5 19 2.262756940345543 0.0236506766305821 5.009708737864078 15.96359223300971 0.918103407248628 0.3572194322029593 2.4583724414330383 3.147064390877318 0.9947617981182544 0.3055434177582076 0.1054558494423211 0.0370108517080311 0.0241494832296601 0.2062787432424993 0.0964581122486521 +Organic cation transport 5 8 2.2619136737800214 0.0237027373837717 2.191747572815534 5.524271844660194 1.626219676916526 0.1372808582950073 1.481153399412497 1.209546654977186 0.871004228766265 0.1892257790071234 2.354438987341288e-05 1.0 0.0009512881710705 0.0001077354659702 0.0003493380530507 +Toll like receptor signaling pathway 7 15 2.2575828252868497 0.0239716804048493 3.6529126213592233 14.475728155339803 0.4591583663944621 0.4629288770135975 2.064121680704246 2.5201890058346033 0.9793418922124256 0.3026110620517385 0.1239949490522067 1.0 1.0 0.0879467854530582 0.1252393293409926 +Glycerolipid metabolic process 33 71 2.243260169097765 0.0248800422805768 16.934466019417474 64.79854368932038 -0.000323163470851 0.4552448147740581 9.046432352430308 10.372466251166422 1.3758971299503038 0.353332456533291 0.0631207776814862 0.314067280031489 0.4096389444513685 0.068452450559718 0.0149540449076263 +Regulation of blood pressure 9 20 2.240232987138911 0.0250758011694736 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0783748786893149 1.0 0.0171810218627354 0.0484766154729776 0.0587745096161565 +L alpha amino acid transmembrane transport 8 11 2.236886840799591 0.0252937368314425 4.480582524271845 10.533980582524272 0.7590361902351016 0.3223730555033793 2.606398335255894 1.1951807271273862 1.273814103695318 0.3116596719827348 0.4375879146969009 1.0 1.0 0.5479465724917809 0.0717785358518721 +Protein localization to lysosome 3 16 2.227684446333845 0.0259015649252729 3.5364077669902914 14.37621359223301 0.6191344010889903 0.3619681772746835 2.0811532251007954 2.18038858944462 1.1869570048706093 0.3022181269423334 0.1334837777517871 0.1573929974646098 0.2957660567507726 0.0568103259660642 0.1000231598892582 +Hormone biosynthetic process 5 10 2.2139239510983417 0.0268340108179752 3.2766990291262137 8.762135922330097 0.5893833627772115 0.3611309387757575 1.7820956292372838 1.0801489024333786 1.1172063688590312 0.2892911953740955 0.0098192787047171 1.0 0.2182850433665622 0.0030679298819029 0.0012077790264312 +Protein n linked glycosylation 11 19 2.206798050104392 0.0273281713581468 6.177184466019417 18.78640776699029 0.2004880128160887 0.4683260162783809 3.1676710128395498 3.0254598797887766 1.208633498192774 0.333447209788965 0.2582272696695035 1.0 0.4176693971260321 0.0459551502585406 0.1376570310950861 +Cotranslational protein targeting to membrane 2 15 2.205832310735737 0.0273957430714413 3.0024271844660193 13.269417475728156 0.6346620653188224 0.4380127158001767 2.1905565042006923 1.12246981946818 0.9482238550798552 0.3119643857898596 0.0046437067491223 0.0037480987371249 0.0149285353010988 0.0111687214620054 0.0138168318064428 +Vitamin transmembrane transport 4 6 2.1995213425356632 0.0278408732702142 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 3.7795586910330368e-06 0.0670021260054199 0.0085055091795532 1.7866814760971125e-05 4.124560666254861e-05 +Regulation of ion transport 19 87 2.1993816203436207 0.0278507984143554 17.640776699029125 78.38349514563107 0.268861732893133 0.649064160670491 6.342726694491137 8.788149535025928 0.7853614201571752 0.3276987608120678 0.0784143431104336 0.1155170513690194 0.2252348268476702 0.1607122575327897 0.0423599518287393 +Dicarboxylic acid transport 11 19 2.196219600531358 0.0280762291076586 5.718446601941747 16.097087378640776 1.1205667041867788 0.2998586575349944 3.584398436287638 2.226340822602054 1.0973546365412417 0.2986830136605488 0.0355040413058726 1.0 1.0 0.077109656392341 0.0143931802338971 +Sensory perception 7 38 2.19559103249458 0.0281212286763699 8.587378640776699 35.48300970873787 0.2801501425459651 0.4439497622713729 3.631661729137722 5.322347342377745 1.1543967333771397 0.3256888258772134 0.1794586340239834 0.0451831125351794 0.0802569171683539 0.3922621554865629 0.5957710285543606 +Regulation of leukocyte degranulation 3 8 2.1809529725223493 0.0291868950182008 1.6699029126213591 6.470873786407767 0.5853711877145334 0.3457823611194687 1.4305158925119918 1.701406104268744 1.0992219708926214 0.2597166324139169 0.0546082347726425 0.0967463289884207 0.0179304062363867 0.0950158591305352 0.0193421266882966 +Cellular response to biotic stimulus 8 41 2.1771119710343263 0.0294722140918384 8.070388349514563 35.616504854368934 0.7964477296470692 0.4798420500319036 3.1871094803090645 3.824235365857021 0.8467616012566905 0.3489796792314515 0.1314021324162655 0.4084389208752779 0.6586784063481552 0.0520904988609164 0.0934469871717584 +Er nucleus signaling pathway 6 15 2.168348881119164 0.0301321519339698 4.563106796116505 13.361650485436892 0.3617919622488442 0.4304556920046536 2.3428051517114805 1.3174649068389608 1.1974910326877934 0.3346175168774911 1.0 1.0 1.0 0.0014933754194455 0.0014045871996462 +Lipoprotein biosynthetic process 7 18 2.16767460800592 0.0301834527416617 3.837378640776699 12.817961165048544 0.5159177916871569 0.4870101230655305 2.4216380804227313 3.0215034704254133 0.9442820469649724 0.3192432047465013 0.0270008570112525 1.0 0.465472661331458 0.0199702538754952 0.0133209057752572 +Purine containing compound transmembrane transport 6 10 2.1640904360526303 0.0304574093758283 3.6432038834951457 8.228155339805825 0.8480777288434221 0.3004167480224937 2.0847056152178514 1.431742605530374 1.2278207398320582 0.2967021731271802 0.023528073884608 1.0 1.0 0.0039601236721776 1.4506528933989392e-06 +Sphingoid metabolic process 3 6 2.15082271320343 0.0314901956276736 2.337378640776699 5.174757281553398 0.8258730035764346 0.2192038420096116 1.196784089801513 0.5941001920342514 1.4738240163378542 0.2563928956394505 1.6615978205831535e-05 0.0009141595337786 1.4841791595772974e-06 5.809602188645229e-05 0.0008775482534874 +Anatomical structure maturation 5 38 2.136333824210644 0.0326522137729816 6.815533980582524 30.893203883495147 0.3841260505655395 0.5416451005267833 3.09006416754166 4.620895179443306 0.9281404590939007 0.3269797675509184 0.0139755779496151 0.4111963711020351 0.2914606489381419 0.0539446143143092 0.4698549321358905 +Cellular response to chemical stress 17 90 2.1304717632819576 0.0331326845973267 15.75728155339806 79.70145631067962 0.402779466671678 0.6562176319163813 6.265123092751621 7.907578877532739 0.7656094121344978 0.3407433272819883 0.1160874085559204 0.298663113634634 0.1842996410277677 0.1114778048091702 0.0367130830693117 +Cellular ion homeostasis 33 96 2.130327594081247 0.0331445769417781 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 0.193101073974987 0.7215494755704439 0.4767337492216527 0.0607852300305852 0.0121519153563436 +Regulated exocytosis 9 38 2.127047433185363 0.0334161422669845 9.385922330097088 34.342233009708735 0.5889869251407832 0.528096964379338 3.868480531815476 4.573760415025692 0.9122431884356956 0.3457208176316948 0.352354265407259 0.4328077398558957 0.3193106634381686 0.1642439557971227 0.0686907338529108 +Antigen processing and presentation of peptide antigen via mhc class i 8 12 2.1195942552069584 0.0340402773717569 3.5533980582524274 10.33980582524272 0.9522781165124746 0.321717188118692 1.7458864571217907 1.7766194475253527 0.972074824811495 0.2764762653101907 1.0 1.0 1.0 1.0 0.2857589636949358 +Vesicle docking 8 19 2.1108681775196616 0.0347836440081512 5.046116504854369 16.300970873786408 0.2955335573812314 0.5566344803804099 2.726231700974349 2.3037957343391864 0.8857805503827542 0.3078464388536641 0.1819837603944453 1.0 1.0 0.2895837506203981 0.0633296250195141 +Gpi anchor metabolic process 3 7 2.107362984856916 0.0350861275628044 2.400485436893204 5.657766990291262 0.3080589762515228 0.4676033624934861 1.4738167072879584 1.5318187882629617 1.0335174561584772 0.3098879122060578 0.3065127812497425 1.0 1.0 0.0877027952007016 0.0164342866074706 +Tail anchored membrane protein insertion into er membrane 6 10 2.099837177646149 0.0357431665998198 3.237864077669903 9.78883495145631 0.7455035093084798 0.3610190702677224 1.8292985819470449 1.3170176672565082 1.0475888307659635 0.3008611564480194 0.2433127023310735 0.0713092569444504 0.1405588989726414 0.3192924621263296 0.000705408490983 +Antigen processing and presentation of endogenous peptide antigen 6 8 2.0980151569506926 0.0359038064697703 2.638349514563106 6.390776699029126 1.097011591019633 0.2766562869747734 1.460743657586565 1.3760123823390067 1.0015631459591094 0.2785574288267012 1.0 1.0 1.0 1.0 0.1434177214303139 +Organelle fusion 22 56 2.097218141669869 0.0359742692609037 14.74514563106796 45.383495145631066 0.6448767361523368 0.5292766623385164 6.293825046556003 6.576179389035289 1.1045479661060835 0.3741954647136961 0.0502690771208171 1.0 1.0 0.1416993000009355 0.0036991475921917 +Export from cell 38 159 2.0948955561274647 0.0361802779926954 32.60436893203884 135.66747572815535 0.3992493838217476 0.6865741169713714 10.348597782214936 15.653208065897076 0.76303420232271 0.3488015490888403 0.0659473902859541 0.3144749357032919 0.1073245514730389 0.1382340355019601 0.0082425285670563 +Export across plasma membrane 6 10 2.088716688038237 0.0367332337357169 3.342233009708738 8.672330097087379 0.659462409318522 0.3364871063656119 2.046038764373277 1.5847916183398325 1.1961171404298503 0.3001696886640556 0.0941229184977135 1.0 0.2473900535744361 0.1586010561439087 0.0132180269039013 +Sodium ion transmembrane transport 8 25 2.079771802156546 0.0375464686353042 6.230582524271845 19.861650485436893 0.3704792335969762 0.5741696766418313 3.3118992073574036 3.0326356242212613 0.8979196459015502 0.333569210239074 0.715811149518966 1.0 1.0 0.243885150604861 0.0216582416568388 +Regulation of systemic arterial blood pressure 3 8 2.0654955977860507 0.0388761316387176 1.9514563106796117 7.480582524271845 0.6591644372092078 0.3227631999327531 1.1543807719023411 1.5318976272183211 1.1594175747176596 0.2663405748898474 0.3968926535471839 1.0 0.2402159343378795 0.1502583189770621 0.1610434863229046 +Pattern recognition receptor signaling pathway 11 33 2.0574058060489797 0.0396472071257418 6.783980582524272 30.48543689320388 0.3893983283533752 0.5277852242642479 3.0860531364168065 4.421623999132768 0.9404779897396882 0.3335139395352661 0.1136811483521929 1.0 1.0 0.1106968565433836 0.0717381307100851 +Homologous chromosome pairing at meiosis 3 9 2.048053925374783 0.0405547158241392 2.4975728155339807 8.245145631067961 0.965829654578573 0.3348869860078453 1.4047402178514554 0.97323438747629 0.9242483632276672 0.2995534430572119 0.2943074061969476 1.0 1.0 0.3817570354203927 0.0138168318064428 +Generation of precursor metabolites and energy 43 188 2.0399675501164536 0.0413535578532131 44.949029126213595 180.5631067961165 -0.1202876390878839 0.6299517985345108 17.371716328089683 11.726387058877684 1.0916009946594227 0.3457966740088026 0.0046033174941765 0.0065256902697462 0.0023658850385718 0.0004757382298257 1.0032392720559145e-06 +Metal ion export 4 10 2.039892348032788 0.0413610490643758 3.779126213592233 8.553398058252426 0.5059205316086877 0.4155863674545267 2.112664358767855 1.499049247815051 1.150738830143596 0.3315496346975708 0.3065127812497425 1.0 1.0 0.396459747437317 0.002692648903577 +Endoplasmic reticulum unfolded protein response 8 22 2.0394599026372378 0.0414041491674745 5.922330097087379 20.817961165048544 0.3028076268112233 0.5117002472852509 2.747246884507101 1.9665572199818449 1.041467084382159 0.3322997623752832 0.2389806632995488 1.0 0.4008133358280547 0.0388428633787512 0.003978057245179 +Long chain fatty acyl coa biosynthetic process 3 8 2.039085855706435 0.0414414596007821 2.6067961165048543 6.645631067961165 0.2459085958317533 0.3937710552533847 1.6983008147735923 0.8926100812185768 1.1931980478816402 0.3084504867564762 0.0268439946301445 1.0 1.0 0.004864195908138 0.0047081007231922 +Negative regulation of autophagy 5 27 2.0308809340344665 0.0422670743065192 5.063106796116505 24.313106796116504 0.449887145270975 0.5377284095479077 2.9855473971181983 2.929018368027943 0.8516059018543028 0.3205218740462018 0.0283407102876468 1.0 0.4705382708629992 0.0745088937074816 0.1019032295441742 +Inorganic anion transmembrane transport 5 11 2.022052960047346 0.0431708809178557 3.4101941747572817 8.983009708737864 1.1245392058053427 0.2357455210082705 2.3748669786284156 1.7214248641786654 1.1968417731555627 0.2697184972505711 0.0888202059650672 1.0 0.2402159343378795 0.1502583189770621 0.1610434863229046 +Regulation of oxidoreductase activity 5 18 2.022011151507808 0.0431751998252147 4.745145631067961 16.524271844660195 0.8435277245089666 0.3527293456818395 2.542951562396442 1.641953963820047 1.0033906386071183 0.2899852749738094 0.2389806632995488 0.025564151584756 0.0916480459892936 0.0088741125605978 0.0439179902920056 +Regulation of secretion 19 103 2.020911480054574 0.0432889293014167 19.521844660194176 89.43203883495146 0.3107106293169513 0.7189453252223079 6.646190857017904 10.524485676543694 0.6342572440447461 0.3131519415494544 0.0565705788315487 0.141249366726494 0.1281498943797281 0.136419823773943 0.0541392892004884 +Peptide catabolic process 3 11 2.017026431088722 0.0436927551134944 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 0.0417999766536677 0.0841142186818086 0.16464692140167 0.0009060327870608 0.0114804089950453 +Ceramide transport 2 5 2.0153956705303786 0.0438632077167788 1.779126213592233 5.310679611650485 0.994079753441996 0.2057455404068654 1.027416031856974 0.785538294365343 1.3065287972688011 0.2361222749942 0.0012731085823663 1.0 0.1157837219692003 0.0031665778749487 0.0220005392397008 +Positive regulation of mitochondrial translation 3 9 2.014496353520951 0.043957447331498 1.8155339805825244 7.439320388349515 1.1233950947475233 0.2654033071264799 1.4295601388514203 1.5544197944414198 1.0052042080836443 0.2741718924063684 0.0268439946301445 0.0670021260054199 0.0085055091795532 0.048077110185513 0.0047081007231922 +Leukocyte degranulation 3 12 2.007103039641839 0.0447386926507227 2.4975728155339807 10.640776699029129 0.3472154736144288 0.4941421599928397 2.083801122584472 2.129790403708522 0.897541840282569 0.2866860077772345 0.1161779578639089 0.145591480261755 0.0404941431409166 0.1927267877862009 0.0784062010361378 +Prostate gland development 1 7 2.005515752935236 0.0449079383721415 1.6092233009708738 5.975728155339806 0.8122203292357496 0.3302673624761357 1.2128808594676108 0.7270055647304389 1.0647320376486975 0.2858771068016162 0.0995145929386559 1.0 1.0 0.167027726091139 0.4430292723950975 +Amyloid precursor protein metabolic process 5 20 1.99779852774179 0.0457385070348557 5.91747572815534 20.04368932038835 1.2306110398413417 0.2828388345239639 2.574706211328507 3.0661056512526157 1.0127867956133585 0.2841981221806073 0.0691272889323803 0.2249237324498754 0.0945439937832932 0.1417325722282816 0.0473842035132311 +Adp transport 4 5 1.9960124045218912 0.0459325726016865 2.3689320388349513 4.201456310679611 0.5019942413211786 0.3489879061320977 1.2147179245232118 0.4188493432764195 1.248361495348926 0.3086395860172816 0.0833954900498324 1.0 1.0 0.0053511077329156 2.5140092208675777e-07 +Multi multicellular organism process 5 28 1.985729890461472 0.0470633241838382 5.817961165048544 26.4004854368932 0.4199141861061661 0.4886319217993659 2.805744405393114 2.878999920293513 0.979235550100524 0.3132681877599969 0.0591976461210597 0.0583172812679527 0.0459278250864885 0.0154579474619112 0.0510834926630842 +Regulation of regulated secretory pathway 5 22 1.9853655542247188 0.0471038154359437 5.135922330097087 19.024271844660195 0.5532028818011353 0.482650154445206 2.517120190261048 2.8085156919839167 0.8466655843360735 0.3050640843792452 0.1201962091222878 0.2771282599295266 0.140743998387736 0.0844835592581437 0.119176962021344 +Stem cell proliferation 1 11 1.982197239921284 0.0474571694826158 2.371359223300971 11.266990291262136 0.2871855378077091 0.5682911182372676 1.937232310875086 1.1262868238661403 0.7998448963266326 0.2886312572020901 0.1634663128754785 1.0 0.0592322030833591 0.2630336655349493 0.6062374262015534 +Regulation of protein exit from endoplasmic reticulum 4 7 1.9821853419327395 0.0474585006241179 2.487864077669903 6.131067961165049 0.614536574202818 0.458469843561175 1.597129798474628 1.7824129563144424 0.9381550143256092 0.3206976005104832 1.0 1.0 1.0 1.0 0.068509275445109 +Antigen processing and presentation of peptide antigen 10 14 1.9817776506087 0.0475041319143818 4.050970873786408 11.99271844660194 0.9279525789651738 0.3302951212632576 1.9792182503824105 1.8740552023113428 1.0022067378347963 0.2823588878170496 1.0 1.0 1.0 1.0 0.4912718938671931 +Small molecule biosynthetic process 43 153 1.980927560623884 0.0475993978087345 30.1626213592233 140.1359223300971 -0.2118875258063249 0.5925209339102029 11.020733369529554 11.156476236401208 0.9278582087324496 0.3439646400407032 0.0022614766846099 0.0706490962797009 0.0046436822447268 5.810026685121856e-06 3.477047573907525e-07 +Mitochondrial atp synthesis coupled proton transport 7 10 1.977843945879886 0.0479463141395655 3.9927184466019416 10.769417475728156 0.5022502301293951 0.29867761594221 2.4440229028906213 0.8937412640542226 1.3849431163992842 0.2834040324316194 0.2692522225630656 0.0798652174269664 0.1566927560007753 0.3512730357569927 0.0094142249651338 +Negative regulation of protein secretion 4 10 1.975979035126082 0.048157151709417 2.366504854368932 8.674757281553399 0.7907680055493084 0.3977556251115637 1.568545308844716 1.6283423250335054 0.8427072898625886 0.2857999704117771 0.0145822304975559 0.1296041755344474 0.2473900535744361 0.0334599986224988 0.0132180269039013 +Atp biosynthetic process 11 19 1.9717612077145208 0.0486368726730483 6.262135922330097 20.148058252427184 0.2780500302004456 0.4469732075673486 3.3282000880634137 1.2978402958376112 1.0861992627517016 0.3097712264878526 0.1513244135942271 0.0145132325721006 0.0543070281832774 0.0686482214123472 0.00265760740995 +Positive regulation of blood circulation 3 5 1.9706721759938368 0.0487613850865296 1.6116504854368932 3.924757281553398 0.6685578971888424 0.3646934888838808 1.007091454748733 1.005648459742718 1.1685725886577618 0.3064822812176077 1.0 1.0 1.0 0.2683545351423047 0.0026623648375823 +Maintenance of protein location in cell 8 23 1.9677768487072071 0.0490937190902567 4.963592233009709 20.74757281553398 0.5138976626555444 0.4828559702191822 2.90064182866346 2.9061984196552437 0.947299732036647 0.3164077327541715 0.2071127419701942 0.2030241760524146 0.3716405295428093 0.1100030290431898 0.000467430048284 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 9 27 1.960639011754028 0.0499211481538508 7.771844660194175 26.825242718446603 1.1714448828781496 0.3436005361805324 3.811248488859092 3.450558374586287 1.1733172803389544 0.345676809182098 0.0471405804839715 0.0197081838633031 0.0097225551320972 0.1001149973848373 0.001612553418853 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cb7f6547cfa67a515992d63d2c8bf111c2c2eb74 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 6655, + "title": "Average number of proteins per term", + "value": 20.91074380165289 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ac51f9a9fbcc61b08cfd1a91d81cea29aad6d2ce --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8bc1ad6a0eec0c1b571f010e78a687a82a55a7e5 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1641 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transmembrane transport 0.612402865094933 5.343226958633482 9.13063228216505e-08 0.0006074590281373 0.0006076435783847 230 Q8WWC4,O60830,Q9NS69,Q99595,P53007,Q8N4V1,P28288,P21796,Q9NRA0,Q9H2J7,P45880,O75964,Q15629,Q8WTV0,P22466,Q9UDW1,Q70HW3,P08183,Q9UHG3,Q9C0H2,O43772,P04062,Q9BSK2,Q96QD8,Q8TB61,Q9HC07,Q9H2D1,O75844,Q9UBX3,Q9HD20,P27105,P38435,Q15041,Q9HC21,Q86VD7,P35670,Q5SR56,P13073,Q8IUH4,O14925,Q6KCM7,Q8IXU6,Q14728,P16615,Q9Y277,P46934,Q9Y6M7,Q9UM00,P00403,Q13423,P12236,Q9UMX0,Q07820,P23786,Q6P4A7,Q12959,P08574,O96008,Q96ER9,O95202,Q6P4Q7,P30825,O95563,P24539,P05023,O43808,Q8NHS3,Q7L0J3,Q99623,P0CG08,O43615,Q6NUK1,P12235,O75915,P05141,O14678,Q96AQ8,Q96NB2,Q92581,Q4KMQ2,P56385,O75381,O75947,Q8TBP6,Q9UJS0,P41440,P52789,P51790,P06576,P05067,Q03519 91 +Ion transmembrane transport 0.5969887946575535 4.978430050319615 6.410210182153291e-07 0.0042569098070449 0.0020609868456294 169 Q8WWC4,Q15041,P53007,Q9HC21,Q86VD7,Q8N4V1,Q9UMX0,P21796,Q9NRA0,P0CG08,P35670,P45880,O75964,P13073,Q8IUH4,P12235,Q6P4A7,O75915,P05141,P22466,Q12959,P08574,Q6KCM7,Q9UDW1,Q70HW3,Q96AQ8,Q96ER9,Q96NB2,O95202,Q6P4Q7,P08183,Q9UHG3,Q14728,P30825,Q92581,Q4KMQ2,P56385,Q9C0H2,P16615,O43772,Q9Y277,O95563,P46934,O75947,Q9Y6M7,Q9UM00,P24539,Q9UJS0,P00403,P05023,Q13423,P41440,O43808,Q8TB61,P06576,Q9HC07,Q9H2D1,O75844,P05067,P12236,Q99623,Q9UBX3,P51790,Q9HD20,P27105 65 +Mitochondrion organization 0.5722745515108286 4.782835992192249 1.7283914483349464e-06 0.011436554707043 0.0020609868456294 200 P14406,Q8WWC4,O60830,Q9NS69,Q99595,Q69YU5,P21796,Q9NVH1,Q9H061,P45880,Q53H12,Q96CU9,O43676,P49257,Q8N4H5,O95140,P53365,Q9UDX5,Q5TC12,Q13505,O75880,Q9Y2R0,Q96A26,P04062,Q86Y39,Q9BSK2,P03886,O43819,Q96TA2,Q8N2A8,Q99536,Q9NX14,Q9Y6C9,P30536,Q9Y5J9,Q9Y3D6,Q9GZT3,Q99797,O75153,O14925,Q9UG56,Q9Y6M9,P55786,Q5XKP0,Q15070,Q9P0J0,Q9Y5J6,P27544,Q6UXV4,P02545,Q16891,Q10713,Q9NVI7,Q9BUB7,Q9H4A6,Q96RL7,O96008,Q8TB36,O95202,O95168,P51970,Q9H3K2,O96000,Q99623,O60313,Q9Y375,O43615,Q9Y512,Q9NX63,P12235,P05141,Q5T9A4,O75431,Q8N183,Q96I36,Q6DKK2,P51572,Q8TB37,P52789,P04179 80 +Membrane organization 0.5356690756136605 4.38824207813908 1.142705445400516e-05 0.0732277993825168 0.0020609868456294 246 Q9P0I2,Q8WWC4,Q9NS69,Q8N4V1,Q9NVH1,P45880,Q96GD4,Q53H12,Q15629,P49354,Q8N766,O95140,P49755,Q9Y6B6,P50897,Q15392,P08183,Q14849,Q13505,Q9UEU0,Q9P2W9,O75844,Q9NQC3,P30536,Q8IXJ6,Q86XL3,Q9NZJ7,Q15041,Q16739,Q96CP7,O60499,O15118,O43760,Q5XKP0,Q96A33,O75955,P16615,Q15070,Q15363,P57088,Q9P0J0,Q9Y5J6,Q6UXV4,P02545,Q16891,Q12846,P46379,Q9H4A6,P50402,Q12959,O95202,O15121,Q12770,Q9BTV4,Q9H3K2,O15400,Q9UH99,Q12981,Q5SQN1,O15258,O60313,Q5JTV8,Q9NPA0,Q00765,Q9NR31,Q9Y512,Q9NX63,Q5J8M3,P12235,P05141,Q9NZ43,O43681,O75431,Q9UQB8,Q86Y82,Q8NHH9,Q4KMQ2,P20700,O94901,P61916,P41440,P52789,O14656,P51790 84 +Ion transport 0.5370279365190003 4.358142529367521 1.3117095333026184e-05 0.0835931394072401 0.0020609868456294 225 Q8WWC4,P53007,P28288,Q8N4V1,P21796,Q9NRA0,P45880,O75964,P22466,Q9UDW1,Q70HW3,P08183,Q9UHG3,Q9C0H2,O43772,Q96QD8,P07602,Q8TB61,Q9HC07,Q9H2D1,O75844,Q9UBX3,O15173,Q9HD20,P27105,P30536,Q9NZJ7,Q15041,Q9HC21,Q86VD7,P35670,P13073,Q8IUH4,Q6KCM7,Q14728,P16615,Q9Y277,P46934,Q9Y6M7,Q9UM00,P00403,Q13423,P12236,Q9UMX0,O76024,Q6P4A7,Q12959,P08574,O96008,Q08722,Q96ER9,O95202,Q6P4Q7,P30825,O95563,P24539,P05023,O43808,Q7L0J3,Q99623,P0CG08,Q96S66,Q6NUK1,P12235,O75915,P05141,O43681,Q96AQ8,Q96NB2,Q92581,Q4KMQ2,P56385,O75947,Q9UJS0,P41440,O14656,P51790,P06576,P05067 79 +Anion transport 0.658237163058021 4.1711518885623455 3.0306376296973525e-05 0.1826533603343663 0.0020609868456294 79 Q9NZJ7,Q15041,P53007,Q9HC21,Q86VD7,P28288,P0CG08,P21796,P45880,Q96S66,Q6NUK1,P12235,O75915,P05141,Q6KCM7,O43681,Q08722,Q96NB2,P08183,Q9UHG3,Q14728,P30825,Q92581,Q4KMQ2,Q9C0H2,Q9Y277,O95563,Q9Y6M7,Q9UJS0,Q96QD8,P41440,O43808,P07602,Q8TB61,Q9H2D1,Q7L0J3,P12236,Q9UBX3,P51790,P30536 40 +Membrane lipid metabolic process 0.7646283493070927 4.171112702680216 3.031158905009157e-05 0.1826817151695995 0.0020609868456294 43 Q9NZJ7,Q16739,Q9NRA0,Q96G23,P16278,Q9H490,Q06136,Q5H8A4,Q8NCC3,Q9NZ01,P50897,O15121,Q99805,Q9P035,P04062,Q6Y1H2,O43292,Q13510,P07602,P27544,P17900,Q92643,O95470 23 +Mitochondrial transport 0.6208619765572706 4.146415047753193 3.377214012334484e-05 0.2012900279705167 0.0020609868456294 88 Q9Y5J9,Q9Y3D6,Q8WWC4,O60830,Q9NS69,Q99797,Q99595,P36542,Q10713,O43615,P45880,Q9Y512,Q53H12,O75964,Q6NUK1,P23786,P12235,P05141,O14925,P49257,Q8N4H5,O75431,O95140,O96008,P55786,Q8TB36,Q14849,P56385,O43772,P51572,O75947,Q15070,P24539,Q9UJS0,Q9P0J0,Q9Y5J6,P52789,Q9UBX3,P06576,P30536 40 +Lipid metabolic process 0.4980883445390429 4.1030478229632745 4.07742926897825e-05 0.2376568145767932 0.0020609868456294 305 Q9BQE5,P09960,Q9NRA0,Q9H6V9,Q16850,Q06136,P37268,Q8WTV0,P22466,Q8NCC3,P07099,P50897,Q15392,O76062,Q14849,Q8N4Q0,Q8NF37,P04062,P51648,Q13510,Q86YN1,Q9HB40,Q8N2A8,P07602,O75844,Q9NPH0,Q15800,Q14739,O14773,P30536,Q96N66,P40939,O95470,P38435,Q8IXJ6,Q9NZJ7,Q16739,O15118,Q96G23,Q9UKU0,Q5H8A4,P48449,Q9UG56,Q53GQ0,O00116,Q99805,O95864,Q9P035,Q9H7Z7,Q92604,Q6Y1H2,O43292,Q9BT22,P16435,Q14534,P27544,Q13011,P17900,Q92643,Q10713,P16278,Q9H490,Q9UBM7,P23786,Q6NUM9,P21964,Q16134,Q9NZ01,O15121,Q12770,Q9BTU6,Q9HCL2,Q9NUQ2,Q2TAA5,P0DMN0,O76054,Q6IAN0,O00767,Q9BWD1,P05023,P49748,O43808,Q99735,Q99623,P04035,O15254,Q8NCG7,A1L0T0,O14678,O43681,Q8N5B7,Q9Y394,Q8NHP8,O14735,P61916,O14880,Q9NTJ5,Q96SU4,Q9UKR5,Q9BXW6,P06576,P05067,O15269 103 +Anion transmembrane transport 0.7377973849267327 4.085547875991013 4.397293189328799e-05 0.2537139416568156 0.0020609868456294 49 Q15758,Q15041,P53007,Q9HC21,Q86VD7,P21796,P45880,P33527,P12235,O75915,P05141,P08195,Q96NB2,P08183,Q9UHG3,Q14728,P30825,Q92581,Q4KMQ2,P51798,O75746,O95563,Q9Y277,Q9Y6M7,Q02978,Q9UJS0,P53985,P41440,Q9Y619,O43808,Q8TB61,Q9H2D1,Q9H9B4,P12236,Q9UBX3,P51790 36 +Sphingolipid metabolic process 0.7932014090401099 4.070715369568736 4.686898726413702e-05 0.2679602183616286 0.0020609868456294 33 Q9NZJ7,Q9P035,P07602,Q16739,Q8NCC3,Q9NRA0,P04062,P27544,Q6Y1H2,Q96G23,Q9NZ01,P50897,P16278,Q13510,Q06136,P17900,Q99805,O95470 18 +Cation transmembrane transport 0.5583826352419381 3.9981650414256857 6.383543611221398e-05 0.3461245488598126 0.0023866563332965 128 Q8WWC4,Q9UMX0,Q9HC21,Q8N4V1,P21796,Q9NRA0,P35670,O75964,P13073,Q8IUH4,P12235,P05141,P22466,Q12959,P08574,Q6KCM7,Q9UDW1,Q70HW3,Q96AQ8,Q96ER9,Q96NB2,O95202,Q6P4Q7,P30825,Q92581,Q4KMQ2,P56385,P16615,O43772,P46934,O75947,Q9Y6M7,Q9UM00,P24539,P00403,P05023,Q13423,P06576,Q9HC07,P05067,Q99623,P51790,Q9HD20,P27105 44 +Lipid biosynthetic process 0.5215595707114313 3.958012569735757 7.557598148544287e-05 0.3952723959145972 0.0026332887789823 163 Q10713,Q16739,P28288,Q9NRA0,Q53H12,Q16850,Q96G23,Q06136,P37268,O75477,Q8WTV0,Q9UKU0,Q5H8A4,P48449,Q9H490,Q9UBM7,P04035,Q8NCG7,Q9UG56,Q8NCC3,Q53GQ0,Q9NZ01,O00116,Q15392,O76062,O15121,Q99805,Q14849,Q12770,Q8NF37,O95864,Q9BTU6,Q9P035,Q9HCL2,Q9NUQ2,Q8N5B7,O76054,Q9H7Z7,P04062,Q6IAN0,Q92604,Q6Y1H2,O00767,O43292,O14735,Q13510,Q86YN1,P16435,P05023,P49748,Q9NTJ5,Q96SU4,Q14534,Q9NPH0,Q9UKR5,Q15800,P27544,Q9BXW6,Q14739,O15269,P30536,Q96N66,Q92643,O95470 64 +Steroid metabolic process 0.6442313803746388 3.9498549236202 7.819857606805591e-05 0.4057361536781915 0.0026663751932778 76 Q9BQE5,P28288,O15118,Q16850,P37268,Q9UBM7,Q8WTV0,P04035,P48449,P22466,Q53GQ0,Q15392,O76062,Q12770,Q14849,P0DMN0,O76054,P04062,Q13510,P16435,P61916,P05023,P49748,Q96SU4,Q14534,Q9UKR5,Q15800,Q9BXW6,Q14739,P05067,P30536,O95470,P38435 33 +Inorganic ion transmembrane transport 0.5496590567493568 3.8553912515602513 0.0001155446860876 0.5365210514119624 0.003447666133044 122 Q8WWC4,Q9UMX0,Q8N4V1,P21796,Q9NRA0,P35670,O75964,P13073,Q8IUH4,P12235,P05141,P22466,Q12959,P08574,Q6KCM7,Q9UDW1,Q96AQ8,Q96ER9,O95202,Q6P4Q7,Q9UHG3,Q92581,Q4KMQ2,P56385,P16615,P46934,O75947,Q9Y6M7,Q9UM00,P24539,P00403,P05023,Q13423,P06576,Q9HC07,Q99623,Q9UBX3,P51790,Q9HD20,P27105 40 +Mitochondrial transmembrane transport 0.6978598472146396 3.8220563882050977 0.0001323434162534 0.5855503240146251 0.0037319721829099 51 Q8WWC4,O60830,P36542,P53007,Q99595,O43615,P21796,Q9UJZ1,O75964,P23786,P12235,Q6P4A7,P05141,P56134,O14925,O96008,Q96AQ8,Q96ER9,Q96NB2,O95202,P56385,O75746,O43772,O95563,O75947,Q9BSK2,Q9UJS0,P24539,Q9Y619,Q9H2D1,P12236,P06576 32 +Organic anion transport 0.6924469731908492 3.812381083458741 0.0001376344527286 0.5998918215579747 0.0038464329527473 53 Q9NZJ7,Q15758,Q15041,P53007,Q9HC21,Q86VD7,P28288,O60831,Q9H2J7,P33527,Q6NUK1,P12235,O75915,P05141,Q6KCM7,P08195,Q08722,Q8TDW0,Q96NB2,P30825,Q14728,O75746,O95563,Q9Y6M7,Q02978,Q9UJS0,Q96QD8,P53985,P41440,O14908,Q9Y619,P07602,Q8TB61,O43808,Q9H2D1,Q9H9B4,Q7L0J3,P12236,Q9UBX3 39 +Protein targeting 0.535936025580841 3.7075060391209753 0.0002093104266827 0.751697294525828 0.0050469597448312 123 Q9Y5J9,Q9Y3D6,Q9UGP8,Q14108,O60830,Q9NS69,Q99797,Q99595,Q15041,Q10713,Q15005,Q9Y5M8,P13473,O43615,Q9Y512,Q9UNL2,Q53H12,P46379,Q15629,P56589,Q96RL7,Q5BJH7,O14925,P43307,P49257,Q8N4H5,O43681,O95140,O96008,P55786,Q8TB36,Q7Z3B4,P40855,O75381,P46934,P51572,O60725,Q9P0J0,Q9Y5J6,Q5W0Z9,P27105,P30536 42 +Organic acid transmembrane transport 0.7299584495029419 3.6596474375259898 0.000252562495506 0.8138152273999327 0.0056002014165936 33 Q15758,Q15041,P53007,P28288,O60831,Q9H2J7,P33527,P23786,O75915,O14678,P08195,Q96NB2,P08183,P30825,O75746,O43772,O95563,Q02978,Q9UJS0,Q96QD8,P53985,P41440,Q9Y619,Q9H2D1,Q9H9B4,Q9UBX3 26 +Cation transport 0.4908082616558029 3.650750759295243 0.000261474885477 0.824539775141673 0.0056002014165936 169 Q8WWC4,Q9UMX0,Q9HC21,Q86VD7,Q8N4V1,P21796,Q9NRA0,P35670,O76024,O75964,P13073,Q8IUH4,P12235,P05141,P22466,Q12959,P08574,Q6KCM7,Q9UDW1,Q70HW3,Q96AQ8,Q96ER9,Q96NB2,O95202,Q6P4Q7,P30825,Q92581,Q4KMQ2,P56385,P16615,O43772,P46934,O75947,Q9Y6M7,Q9UM00,P24539,Q96QD8,P00403,P05023,Q13423,O43808,P06576,Q9HC07,O75844,P05067,O14656,Q99623,O15173,P51790,Q9HD20,P27105,P30536 52 +Membrane lipid biosynthetic process 0.7682361989128276 3.624287467044719 0.0002897591810089 0.8546523444462929 0.0058791077732147 29 Q9P035,Q16739,Q9H490,P04062,Q9NRA0,P27544,Q6Y1H2,Q96G23,O43292,Q92643,O95470,Q13510,Q06136,Q99805,Q5H8A4 15 +Carboxylic acid transport 0.6854684958694399 3.545216438919773 0.0003922908204929 0.9265542044442588 0.0071722401384085 38 Q9NZJ7,Q15758,Q15041,P53007,P28288,O60831,Q9H2J7,P33527,O75915,P08195,Q8TDW0,Q96NB2,P30825,O75746,O95563,Q02978,Q9UJS0,Q96QD8,P53985,P41440,O14908,Q9Y619,P07602,Q9H2D1,Q9H9B4,Q7L0J3,Q9UBX3 27 +Sterol metabolic process 0.6719090993580878 3.5398738297560555 0.0004003183657848 0.9303764296473525 0.0072710473706859 45 Q9BQE5,O15118,Q16850,P37268,Q9UBM7,Q8WTV0,P04035,P48449,Q15392,O76062,Q12770,Q14849,O76054,P04062,P16435,P61916,P49748,Q14534,Q9UKR5,Q15800,Q9BXW6,Q14739,P05067 23 +Mitochondrial respiratory chain complex assembly 0.6662616010146735 3.4682068198157547 0.0005239438834927 0.9694307390732926 0.0085461925113829 43 Q69YU5,Q9H061,Q9Y512,O43674,Q96CU9,O43676,Q9Y6M9,Q8N183,Q96I36,O95168,P51970,O75880,Q9Y2R0,O96000,Q6DKK2,Q86Y39,Q9BSK2,P03886,Q15070,Q16795,O43819,Q9P0J0,Q8TB37,Q9Y276,Q9NX14,Q9Y375 26 +Organophosphate ester transport 0.7065820628972488 3.429840097399645 0.0006039370436221 0.98205448733976 0.0093469791286174 32 P61916,P05141,Q4KMQ2,Q14108,O43808,Q8TB61,Q9HC21,Q86VD7,Q9H2D1,Q6KCM7,Q8WTV0,Q08722,Q9BSK2,P12236,Q6NUK1,P08183,P12235 17 +Steroid biosynthetic process 0.6327797400394304 3.3331619836822597 0.0008586493552968 0.9967096658686404 0.0120809967431307 52 P28288,Q16850,P37268,Q9UBM7,P04035,P48449,Q53GQ0,Q15392,O76062,Q12770,Q14849,O76054,Q13510,P16435,P05023,Q96SU4,Q14534,Q9UKR5,Q15800,Q9BXW6,Q14739,P30536 22 +Cellular respiration 0.509212242977294 3.249455919819167 0.0011562599675889 0.9995468839003622 0.0156083368849988 103 P14406,O75964,P13073,P15954,O14949,O43676,Q9Y6M9,Q6KCM7,P08574,Q16134,Q9UDW1,P21912,O95168,P51970,P56385,Q9H3K2,O96000,P04062,O75947,Q9BSK2,P03886,Q15070,O75380,P24539,Q9UJS0,P00403,Q13423,P22695,P14735,P06576,Q9Y375 31 +Sphingolipid biosynthetic process 0.7870202481677809 3.2382525048964186 0.0012026431658587 0.99966734573897 0.0161362707032052 21 Q8N5B7,Q9P035,Q16739,P04062,Q9NRA0,P27544,Q6Y1H2,Q96G23,Q13510,Q06136,O15121,O15269,Q99805,O95470 14 +Lytic vacuole organization 0.7251028922321674 3.2363079041940748 0.0012108669504873 0.9996850832607292 0.0162139226468676 27 Q8N511,Q9P253,Q14108,P11117,Q9HC07,Q8NHS3,O75503,P04062,P50897,O14773,P54802 11 +Cellular lipid metabolic process 0.4570511469491735 3.234726278625156 0.0012175939731509 0.9996988870260332 0.0162712608259423 229 P28288,Q9NRA0,Q53H12,Q06136,P37268,Q8WTV0,Q8NCC3,P07099,P50897,Q8N4Q0,Q8NF37,P04062,P51648,Q13510,Q86YN1,Q9HB40,P07602,O75844,Q9NPH0,Q15800,Q96N66,P40939,O95470,Q8IXJ6,Q9NZJ7,Q16739,Q96G23,Q9UKU0,Q5H8A4,P48449,Q9UG56,Q53GQ0,O00116,Q99805,O95864,Q9P035,Q9H7Z7,Q92604,Q6Y1H2,O43292,Q9BT22,P16435,P27544,Q13011,P17900,Q92643,Q10713,P16278,Q9H490,P23786,Q6NUM9,Q16134,Q9NZ01,O15121,Q12770,Q9BTU6,Q9HCL2,Q9NUQ2,Q2TAA5,Q6IAN0,O00767,Q9BWD1,P49748,O43808,Q99735,Q99623,P04035,O15254,Q8NCG7,A1L0T0,O14678,Q8N5B7,Q9Y394,Q8NHP8,O14735,P61916,Q9NTJ5,O15269,Q9UBV2 79 +Alcohol metabolic process 0.5267485394248239 3.221690944795604 0.0012743651566817 0.9997937267052583 0.0168271827732484 89 Q9BQE5,Q10713,Q9NRA0,O15118,Q16850,P37268,Q9UBM7,Q8WTV0,P04035,P48449,Q6NUM9,Q15392,P00374,O76062,Q12770,Q14849,Q9Y394,P0DMN0,O76054,P04062,P51648,Q13510,P16435,P61916,P49748,Q14534,Q15800,Q9BXW6,Q14739,P05067 30 +Mitochondrial membrane organization 0.6243862210682065 3.217301617615062 0.0012940248250343 0.9998190540014258 0.0170192395466478 48 Q16891,Q8WWC4,Q9NS69,Q9NVH1,P45880,Q9Y512,Q53H12,Q9NX63,P12235,P05141,O75431,O95202,Q5XKP0,Q13505,Q9H3K2,Q15070,Q9P0J0,Q9Y5J6,P52789,Q6UXV4,O60313 21 +Carbohydrate derivative transport 0.8043931780801566 3.2127614031855485 0.0013146545373292 0.9998422946224323 0.0172224920195398 19 P61916,P05141,Q9NZJ7,O43808,P07602,Q8TB61,Q9HC21,Q86VD7,Q6KCM7,Q8WTV0,Q08722,P12236,Q6NUK1,P12235 14 +Endomembrane system organization 0.4546420031803475 3.2110590794063705 0.0013224674325245 0.9998502952341398 0.0172671548881185 188 Q9P0I2,Q86XL3,Q5JTV8,Q14108,Q15041,Q16739,Q96CP7,Q9NPA0,Q00765,Q8N4V1,O15260,Q12846,P46379,Q15629,Q5J8M3,Q9H4A6,Q8N766,P50402,O95197,Q9P253,P49257,O43681,P49755,O43760,Q9UL15,Q9UQB8,Q8NHH9,O15121,Q96A33,Q9BTV4,Q4KMQ2,Q9BTU6,Q9UEU0,Q9BVK6,O75955,P16615,P20700,O94901,Q7RTS9,Q9P2W9,Q8TBA6,Q9UH99,Q15363,Q2M389,P41440,P57088,Q12981,O75844,Q8N5M9,Q9NQC3,O14656,Q5SQN1,P51790,P02545,Q9Y3A6,Q8IXJ6 56 +Organic acid transport 0.6123279379814525 3.181819890931599 0.0014635280086729 0.9999415251072078 0.0189121920344054 53 Q9Y3D6,Q15758,Q15041,P53007,P28288,O60831,Q9H2J7,P33527,P23786,Q6P4A7,O75915,O14678,P08195,Q8TDW0,Q96NB2,P08183,P30825,O75746,O43772,O95563,Q02978,Q9UJS0,Q96QD8,P53985,P41440,O14908,Q9Y619,O43808,Q9H2D1,Q9H9B4,Q7L0J3,Q9UBX3 32 +Establishment of protein localization to membrane 0.516369439353234 3.1669218735148523 0.0015406170211265 0.9999650192350568 0.0197930623081022 93 Q9P0I2,Q9Y5J9,Q9Y3D6,Q8WWC4,Q9UGP8,Q9NS69,Q15041,Q9NPA0,Q8N4V1,O15118,Q9Y512,Q9UNL2,Q53H12,P61026,P46379,Q15629,P56589,Q5J8M3,Q9H4A6,Q8N766,Q5BJH7,P43307,O43681,Q9BZG1,Q96A33,P40855,Q9H9H4,Q15070,O60725,Q5W0Z9,Q9P0J0,Q9Y5J6,Q9HD20,P27105 34 +Protein insertion into membrane 0.7122507725337174 3.1554512034498368 0.0016025006960347 0.9999768426033856 0.020498668306066 27 Q9P0I2,Q8WWC4,Q9NS69,Q9NPA0,Q8N4V1,Q9P0J0,O43681,Q9Y5J6,Q9Y512,Q53H12,P46379,Q15629,Q5J8M3,Q15070,Q96A33 15 +Oxidative phosphorylation 0.5942681139867722 3.155036678631515 0.0016047792918798 0.9999771916698752 0.020498668306066 61 P14406,P13073,O75964,P15954,O14949,O43676,P08574,Q9Y6M9,Q9UDW1,O95168,P51970,P56385,Q9H3K2,O96000,O75947,Q9BSK2,P03886,O75380,P24539,P00403,P22695,Q9Y375 22 +Endoplasmic reticulum organization 0.622691205993601 3.1507592846544275 0.0016284664213706 0.999980523030326 0.0207216903139987 44 Q9P0I2,Q15041,Q00765,Q9NPA0,Q8N4V1,P46379,Q15629,Q5J8M3,Q8N766,O95197,O43681,Q8NHH9,Q96A33,Q9P2W9,Q15363,P57088,Q12981,Q8N5M9,Q9NQC3 19 +Alcohol biosynthetic process 0.6278420701231686 3.143046888780569 0.0016719905454427 0.9999854280143312 0.021163282151832 40 P04062,Q9NRA0,Q15800,Q16850,Q15392,P00374,Q13510,O76062,P37268,Q9UBM7,Q12770,Q14739,P16435,P48449 14 +Ceramide metabolic process 0.7587173795738746 3.142920925839129 0.0016727102046376 0.9999854977539 0.021163282151832 22 Q8N5B7,Q16739,Q8NCC3,Q9NRA0,P04062,P27544,Q96G23,P17900,Q13510,O15121,O15269,Q99805,O95470 13 +Secondary alcohol metabolic process 0.6124321477149176 3.122387544360022 0.001793906244397 0.9999935353850492 0.0225679509573953 48 Q9BQE5,O15118,Q16850,P37268,Q9UBM7,Q8WTV0,P04035,P48449,Q15392,O76062,Q12770,Q14849,O76054,P04062,P16435,P61916,P49748,Q14534,Q15800,Q9BXW6,Q14739,P05067 22 +Lipid localization 0.5387066883426921 3.117561154512364 0.0018235410986662 0.9999946943826667 0.0228543616038111 81 Q9BQE5,Q9NZJ7,Q14108,Q16739,O15260,Q9H6V9,O15118,P23786,Q8WTV0,Q99720,P22466,O14678,Q86Y82,P08183,Q14849,Q4KMQ2,O43772,P04062,P61916,O43808,P07602,Q96SU4,Q14534,Q9BXW6,P17900,P30536 26 +Inner mitochondrial membrane organization 0.760798691687059 3.030613384108351 0.0024405753280853 0.9999999133926424 0.0291598362808048 20 Q16891,Q8WWC4,Q9H3K2,Q9P0J0,Q9Y5J6,O75431,Q9NVH1,Q9Y512,O95202,Q6UXV4,Q9NX63,Q5XKP0,O60313,Q13505 14 +Protein targeting to mitochondrion 0.597548646209644 3.024205361788374 0.0024928715868151 0.99999993890118 0.0297312910578038 50 Q9Y5J9,Q9Y3D6,Q10713,O60830,Q9NS69,Q99595,O43615,Q9Y512,Q53H12,O14925,P49257,Q8N4H5,O95140,O96008,P55786,Q8TB36,P51572,Q9P0J0,Q9Y5J6,P30536 20 +Protein transmembrane transport 0.7036160576732361 2.9990423758691582 0.002708296356211 0.9999999854861604 0.0316761199483033 25 O60830,Q9NS69,O14925,Q99595,O43615,O96008,Q07820,Q15629 8 +Aerobic respiration 0.5072237309849439 2.989806074476921 0.0027915461412553 0.9999999916726308 0.0325354458319687 87 P14406,O75964,P13073,P15954,O14949,O43676,Q9Y6M9,P08574,Q9UDW1,P21912,O95168,P51970,P56385,Q9H3K2,O96000,O75947,Q9BSK2,P03886,Q15070,O75380,P24539,P00403,Q13423,P22695,P14735,Q9Y375 26 +Glycoprotein biosynthetic process 0.5833859799647443 2.982570355489136 0.00285838942972 0.9999999946694986 0.033025315372894 56 Q92542,Q9H0U3,O15118,Q9H4A6,Q8NCH0,P04843,Q10472,Q99805,Q2TAA5,Q86SF2,Q9H488,Q86YN1,Q9BT22,O75352,Q8N4A0,P61803,O43505,P46977,Q7LGA3,Q9HC07,Q6ZXV5,Q8TCJ2,Q16706,Q13724,Q8N6G5,Q9Y287 26 +Protein localization to mitochondrion 0.5742589683329163 2.98160545421937 0.0028674127340653 0.9999999949810398 0.033072152071412 61 Q9Y5J9,Q9Y3D6,Q8WWC4,Q10713,O60830,Q9NS69,Q99595,O43615,Q9Y512,Q53H12,O14925,P49257,Q8N4H5,O95140,O96008,P55786,Q8TB36,P51572,Q15070,Q9P0J0,Q9Y5J6,P52789,Q9Y6C9,P30536 24 +Nucleotide transport 0.8075350789339755 2.9676365113850647 0.0030009898871419 0.9999999979421724 0.0342565826739785 16 P05141,O43808,Q8TB61,Q9HC21,Q86VD7,Q9H2D1,Q6KCM7,Q08722,Q9BSK2,P12236,Q6NUK1,P12235 12 +Monovalent inorganic cation homeostasis 0.6275438355015021 2.9492518911943777 0.0031854423007653 0.9999999993993176 0.0360529226387641 33 P05023,Q8N511,Q92544,P0CG08,Q9HC07,Q93050,O75503,Q9Y6M7,P50897,P51790,Q92581 11 +Localization within membrane 0.4370846135383226 2.940971902538513 0.0032718421043556 0.9999999996626188 0.0368428243730736 201 Q9P0I2,Q9Y5J9,Q9UGP8,Q8WWC4,Q9NZJ7,Q9NS69,Q9Y3D6,Q15041,Q9NPA0,Q8N4V1,Q14254,Q9UNK0,O15118,Q9Y512,Q9UNL2,Q53H12,Q12846,P46379,Q15629,P56589,Q5J8M3,Q9H4A6,P49354,Q86YV9,Q8N766,Q5BJH7,O75915,Q92544,Q12959,P43307,O43681,Q96SB3,Q96A33,Q7Z3B4,Q99805,P40855,Q15057,P35613,Q9UEU0,O75955,O15400,Q9UPT5,O00264,Q9HD45,Q92796,Q15070,Q15363,O60725,Q5W0Z9,P41440,Q9BTX1,P07602,Q9H223,Q9P0J0,Q9Y5J6,P35241,P43378,Q13641,O15258,O60826,Q9HD20,P27105 62 +Atp metabolic process 0.474219177000765 2.9341185947499433 0.0033449637356803 0.9999999997929472 0.0376025906435016 112 P14406,Q9UKK9,Q9NRA0,O75964,P13073,P15954,O14949,O43676,Q9Y6M9,Q6KCM7,P08574,Q9UDW1,O95168,P51970,Q9BRR6,P56385,Q9H3K2,O96000,O75947,Q9BSK2,P03886,O75380,P24539,Q9UJS0,P00403,P22695,P52789,P06576,P30536,Q9Y375 30 +Nadh dehydrogenase complex assembly 0.637915224336396 2.892957210871977 0.0038163328446987 0.9999999999911116 0.0407667657808508 31 Q96CU9,P51970,O43676,Q9Y6M9,O96000,Q9P0J0,Q8TB37,Q9Y276,Q9H061,Q8N183,Q86Y39,P03886,Q9NX14,Q15070,Q16795,O95168,Q9Y375,O43674 18 +Sterol biosynthetic process 0.6449047189598357 2.8810785557194074 0.0039631685080405 0.9999999999966674 0.0416007672255678 30 O76054,Q14534,Q9UKR5,Q15800,Q16850,Q14739,Q15392,O76062,P37268,Q9UBM7,Q12770,P04035,P16435,P48449 14 +Proton transmembrane transport 0.5918028578759414 2.875088594572748 0.0040391414467897 0.999999999997994 0.0422649156106693 41 P36542,Q9NRA0,Q9UJZ1,P13073,O75964,P12235,P05141,P56134,P08574,Q9UDW1,Q92581,P56385,O75947,P24539,P00403,P05023,Q13423,Q99623,P51790,P06576 20 +Respiratory electron transport chain 0.5742176444979677 2.85371379547423 0.0043211441306012 0.9999999999996954 0.0445158114383147 52 P13073,P15954,O14949,O43676,P08574,Q9Y6M9,Q16134,Q9UDW1,P21912,O95168,P51970,Q9H3K2,O96000,P04062,P03886,O75380,Q9UJS0,P00403,Q9Y375 19 +Glycoprotein metabolic process 0.5533627700753249 2.830340954420246 0.0046498423014802 0.999999999999966 0.0473160558353991 63 Q92542,Q9H0U3,O15118,Q9H4A6,Q8NCH0,P04843,Q10472,Q99805,Q2TAA5,Q86SF2,Q9H488,Q86YN1,Q9BT22,O75352,Q8N4A0,P61803,O43505,P46977,Q7LGA3,Q9HC07,Q6ZXV5,Q8TCJ2,Q16706,P04844,Q13724,Q8N6G5,P14314,Q9Y287 28 +Cellular monovalent inorganic cation homeostasis 0.6448080518616369 2.8230568329721195 0.0047568138499767 0.9999999999999836 0.0478196316791467 29 P05023,Q8N511,Q92544,P0CG08,Q9HC07,Q93050,O75503,Q9Y6M7,P50897,P51790,Q92581 11 +Atp synthesis coupled electron transport 0.5866316447991401 2.81627982028574 0.0048583331460254 0.9999999999999916 0.0487665265260926 39 P00403,P51970,O43676,Q9H3K2,P08574,Q9Y6M9,O96000,Q9UDW1,O95168,P03886,P13073,P15954,Q9Y375,O14949 14 +Liposaccharide metabolic process 0.7458892720433031 2.803834805837435 0.0050498771322768 0.9999999999999976 0.0499360064120397 18 Q16739,P04062,Q92643,O43292,P17900,P16278,Q99805,Q5H8A4 8 +Inorganic anion transport 0.6400411162064327 2.790523693993732 0.0052622848430994 0.9999999999999994 0.0516300868500643 29 Q4KMQ2,Q9C0H2,P30536,P0CG08,Q9Y277,O43681,P21796,P45880,Q9Y6M7,Q9UBX3,Q96S66,P08183,Q9UHG3 13 +Amino acid betaine transport 0.97415004214667 2.7627911351595738 0.0057309426418283 1.0 0.055515899972879 2 O43772 1 +Regulation of ph 0.67137420184241 2.751080811439474 0.0059398988046106 1.0 0.0573730428805281 24 Q8N511,Q92544,P0CG08,Q9HC07,Q93050,O75503,Q9Y6M7,P50897,P51790,Q92581 10 +Regulation of cellular ph 0.67137420184241 2.751080811439474 0.0059398988046106 1.0 0.0573730428805281 24 Q8N511,Q92544,P0CG08,Q9HC07,Q93050,O75503,Q9Y6M7,P50897,P51790,Q92581 10 +Metal ion transport 0.4567604211194807 2.732917174511362 0.0062776116338512 1.0 0.0593430474762497 115 Q9UMX0,Q8N4V1,P21796,Q9NRA0,P35670,O76024,Q8IUH4,P22466,Q12959,Q6KCM7,Q96ER9,O95202,P16615,P46934,Q9Y6M7,Q9UM00,Q96QD8,Q9HC07,O75844,O15173,Q9HD20,P27105,P30536 23 +Phosphatidylcholine acyl chain remodeling 0.9657207080640616 2.7272219223192815 0.0063870066855051 1.0 0.0598669429465309 2 Q8NF37 1 +Xenobiotic export 0.9601011520089896 2.7034325879430523 0.0068627366964812 1.0 0.0637870289316802 2 P08183 1 +Amino acid transmembrane transport 0.7404233532847448 2.6921927227262468 0.0070983913180762 1.0 0.0655198255503428 17 O75915,Q15758,O75746,Q9Y619,Q15041,Q9H9B4,O60831,Q9H2J7,P08195,Q96NB2,Q9UJS0,Q96QD8,P30825 13 +Intracellular protein transmembrane transport 0.6819844216045635 2.6879584276856803 0.007189034628525 1.0 0.0662394433167387 22 O60830,O14925,Q99595,O43615,O96008,Q15629 6 +Organic hydroxy compound biosynthetic process 0.5429038523583904 2.6876229184712086 0.0071962610845983 1.0 0.0662394433167387 60 P28288,Q9NRA0,Q16850,P37268,Q9UBM7,P04035,P48449,Q15392,P00374,O76062,Q12770,O76054,P04062,Q13510,P16435,Q96SU4,Q14534,Q9UKR5,Q15800,Q9BXW6,Q14739,O15269 22 +Organic hydroxy compound metabolic process 0.4508236492709064 2.6819083137217623 0.0073203519771367 1.0 0.0666391229774867 121 Q9BQE5,Q10713,P28288,Q9NRA0,O15118,Q16850,P37268,Q9UBM7,Q8WTV0,P04035,P48449,Q6NUM9,P21964,P00374,Q15392,O76062,Q12770,Q14849,Q9Y394,P0DMN0,O76054,P04062,P51648,Q13510,P16435,P61916,P49748,Q96SU4,Q14534,Q9UKR5,Q15800,Q9BXW6,Q14739,P05067,O15269,P38435 36 +Ceramide biosynthetic process 0.7795670078784341 2.6804205949480946 0.0073529707182453 1.0 0.0666391229774867 14 Q8N5B7,Q16739,P04062,Q9NRA0,P27544,Q96G23,Q13510,O15121,O15269 9 +Nucleotide transmembrane transport 0.8355176514364296 2.67700619113299 0.0074283262325229 1.0 0.0669666133666142 11 P05141,O43808,Q8TB61,Q86VD7,Q9H2D1,Q9BSK2,P12236,P12235 8 +Regulation of mitochondrion organization 0.5602376286155625 2.674578210411016 0.007482332139109 1.0 0.0672904329537446 46 Q8N2A8,Q96A26,Q9UG56,Q9H3K2,P30536,P21796,Q99536,P27544,Q9Y6C9,O60313,Q9H4A6,P02545,P12235 13 +Regulation of lipid biosynthetic process 0.6120970587492098 2.652016956174333 0.0080012523627954 1.0 0.0700918908228722 30 Q8NF37,P05023,O76054,Q9NRA0,Q92604,Q12770,Q13510,P30536,Q9UBM7,Q8WTV0,P16435 11 +Glycosphingolipid biosynthetic process 0.9474571508850792 2.649682285845467 0.0080567496495864 1.0 0.0704568579737161 2 Q16739 1 +Glycosylation 0.5519734273369691 2.6442210016211605 0.0081879176380672 1.0 0.0715099630988682 50 Q9H0U3,O15118,O75503,P04843,Q10472,Q2TAA5,Q86SF2,P04062,Q9H488,Q86YN1,O75352,Q9BT22,Q8N4A0,P61803,O43505,P46977,Q9HC07,Q6ZXV5,Q8TCJ2,Q16706,Q13724 21 +Calcium ion import into sarcoplasmic reticulum 0.944928350660296 2.638894910962647 0.0083176760410497 1.0 0.0717952452051697 2 O75844 1 +Electron transport chain 0.5163211020903603 2.6382414939770573 0.0083337211356167 1.0 0.0718405623802191 71 P13073,P15954,O14949,O43676,P08574,Q9Y6M9,Q16134,Q9UDW1,P21912,O15121,O95168,P51970,Q9H3K2,O96000,P04062,P03886,O75380,Q9UJS0,P16435,P00403,Q9P0J0,Q9Y375 22 +Phosphatidylglycerol acyl chain remodeling 0.9418375948300056 2.6256934366838096 0.0086472659501231 1.0 0.0738653137726114 2 Q8NF37 1 +Phosphatidylinositol acyl chain remodeling 0.9418375948300068 2.6256934366838096 0.0086472659501231 1.0 0.0738653137726114 2 Q96N66 1 +Protein localization to endoplasmic reticulum 0.5621344270861156 2.597568781319121 0.0093886315046975 1.0 0.0789903194232143 35 P24390,Q15005,Q9Y5M8,O43681,Q9NQC3,Q96HY6,Q9UNL2,O43292,P46379,Q15629,O15258 11 +Protein palmitoylation 0.9305984827198632 2.5775312570885993 0.0099508881325212 1.0 0.0828479956402288 2 Q8IUH4 1 +Atp transport 0.8846045595271546 2.5772431016777246 0.0099591880559253 1.0 0.0828479956402288 8 O43808,Q86VD7,Q6KCM7,Q08722,P12236,Q6NUK1,P12235 7 +Dermatan sulfate proteoglycan metabolic process 0.9300365271143562 2.5751166897923934 0.0100206273475409 1.0 0.0832550249661485 2 Q8NCH0 1 +Regulation of t cell differentiation in thymus 0.9291935937060956 2.571493685587218 0.0101260861922418 1.0 0.0840263137273935 2 O96005 1 +Purine nucleotide transport 0.7759466028605688 2.5671812257054247 0.0102529011839191 1.0 0.0846563987332286 13 P05141,O43808,Q8TB61,Q86VD7,Q6KCM7,Q08722,P12236,Q6NUK1,P12235 9 +Energy derivation by oxidation of organic compounds 0.4402079396231292 2.5650625401230607 0.0103157209707025 1.0 0.0850695453036251 125 P14406,O75964,P13073,P15954,O14949,O43676,Q9Y6M9,Q6KCM7,P08574,Q16134,Q9UDW1,P21912,O95168,P51970,P56385,Q9H3K2,O96000,P04062,O75947,Q9BSK2,P03886,P10253,Q15070,O75380,P24539,Q9UJS0,P00403,Q13423,P49748,P22695,P14735,P06576,Q9Y375 33 +Endoplasmic reticulum membrane organization 0.8449197409701187 2.5596561524109207 0.0104775773118992 1.0 0.0861907008784789 9 Q15041,Q00765,Q12981,Q9NQC3,Q9P2W9,Q15363 6 +Amino acid transport 0.6253718433612174 2.540484685041639 0.0110698941700704 1.0 0.0905038644985487 26 O75915,O14908,Q15758,O75746,Q15041,Q9Y619,O60831,Q9H9B4,Q9H2J7,P08195,Q7L0J3,Q96NB2,Q96QD8,Q9UJS0,Q6P4A7,P30825 16 +Protein insertion into er membrane 0.7700989622272447 2.538007185427654 0.011148569543641 1.0 0.0909236891089845 13 Q9P0I2,Q9NPA0,Q8N4V1,O43681,P46379,Q15629,Q5J8M3,Q96A33 8 +Lipoprotein metabolic process 0.6284683983177203 2.5169396863883975 0.0118379091896787 1.0 0.0944619732102063 25 Q9BQE5,Q5W0Z9,Q16739,P04062,P50897,O43292,Q8IUH4,Q9H490,Q92643,Q5H8A4 10 +Glycerolipid biosynthetic process 0.5329606262637931 2.4996880364848675 0.0124302712976458 1.0 0.0968658729342308 52 Q10713,Q86UL3,Q9H490,Q8WTV0,Q5H8A4,Q8WVX9,Q9UG56,Q8NCC3,Q96BW9,Q8NF37,Q9BTU6,Q9HCL2,Q9NUQ2,Q6IAN0,Q8TBX8,Q92604,Q96S52,O43292,O14735,Q9BXW7,Q9NTJ5,Q9NPH0,Q96N66,Q92643,Q8WWI5 25 +Positive regulation of steroid biosynthetic process 0.91149199213262 2.495091067826045 0.0125924807391379 1.0 0.0972192103468252 2 P16435 1 +Positive regulation of steroid metabolic process 0.91149199213262 2.495091067826045 0.0125924807391379 1.0 0.0972192103468252 2 P16435 1 +Positive regulation of alcohol biosynthetic process 0.91149199213262 2.495091067826045 0.0125924807391379 1.0 0.0972192103468252 2 P16435 1 +Positive regulation of cholesterol biosynthetic process 0.91149199213262 2.495091067826045 0.0125924807391379 1.0 0.0972192103468252 2 P16435 1 +Positive regulation of cholesterol metabolic process 0.91149199213262 2.495091067826045 0.0125924807391379 1.0 0.0972192103468252 2 P16435 1 +Azole transmembrane transport 0.9109300365271108 2.4926556058689076 0.0126791760294078 1.0 0.0975490363881029 2 Q9HC21 1 +Glycerophospholipid biosynthetic process 0.5384880111725907 2.4921169360400657 0.012698422291586 1.0 0.0975842960167494 46 Q10713,Q86UL3,Q9H490,Q5H8A4,Q8WVX9,Q9UG56,Q96BW9,Q8NF37,Q9BTU6,Q9HCL2,Q9NUQ2,Q6IAN0,Q8TBX8,Q96S52,O43292,O14735,Q9BXW7,Q9NTJ5,Q9NPH0,Q96N66,Q92643,Q8WWI5 22 +Response to endoplasmic reticulum stress 0.4644686994365335 2.4910168845619247 0.0127378066338044 1.0 0.0977740520737813 86 Q9GZP9,Q9UMX0,Q8TCT9,O76024,P46379,O75477,P27824,Q96HY6,Q96A33,O14967,P07237,Q6NTF9,O75955,P16615,Q9H3N1,P51572,Q9UBU6,Q15363,Q9UM00,Q9BUN8,P41440,P57088,O95881,Q7Z2K6,Q6ZXV5,Q8TCJ2,Q9Y4P3,O14656,Q9NXW2,O60313,Q9UBV2 31 +Phospholipid homeostasis 0.909525147513343 2.486564266720752 0.0128983270526104 1.0 0.09843849373294 2 Q96CP7 1 +Diacylglycerol biosynthetic process 0.9095251475133412 2.486564266720746 0.0128983270526106 1.0 0.09843849373294 2 Q8NCC3 1 +Flavonoid metabolic process 0.9081202584995768 2.480469093966036 0.0131209637941154 1.0 0.0994010719023473 2 P16435 1 +Catechol containing compound catabolic process 0.9081202584995776 2.480469093966036 0.0131209637941154 1.0 0.0994010719023473 2 P21964 1 +Hormone metabolic process 0.5788597028695579 2.4686946148938747 0.0135606891075383 1.0 0.1022042876678006 31 Q6NUM9,P22466,P42892,O75844,Q53GQ0,O95470,Q9HB40,P30536,Q9UBM7,Q14849,P16435 11 +L amino acid transport 0.7553033584884119 2.463722384060902 0.0137502566867222 1.0 0.1030538338480924 13 O75915,Q15758,O75746,Q9Y619,Q15041,Q9H9B4,P08195,Q9UJS0,Q96QD8,P30825 10 +Regulation of lipid metabolic process 0.5182592494098768 2.463488111565578 0.0137592458358564 1.0 0.1030538338480924 60 Q8NF37,P05023,Q9NZJ7,P49748,P22466,P07602,O76054,Q96N66,O75844,Q9NRA0,Q92604,Q96G23,Q12770,Q13510,P30536,Q9UBM7,Q8WTV0,P16435 18 +Regulation of steroid biosynthetic process 0.7726896390402495 2.46248833639835 0.013797666052016 1.0 0.1031130043479791 12 P05023,O76054,Q13510,P30536,Q9UBM7,Q12770,P16435 7 +Vitamin transport 0.8228114213779585 2.4601739712476225 0.0138869681470112 1.0 0.1033755850317227 9 Q9HC21,Q9H2D1,O14678,P04062,Q8WTV0,P38435 6 +Regulation of hormone biosynthetic process 0.9013767912334903 2.4511589472478597 0.0142397058040715 1.0 0.1043670067468017 2 P16435 1 +Regulation of steroid hormone biosynthetic process 0.9013767912334903 2.4511589472478597 0.0142397058040715 1.0 0.1043670067468017 2 P16435 1 +Membrane lipid catabolic process 0.7678653337868111 2.438801954378446 0.0147360417568578 1.0 0.1070615260828481 12 P04062,P50897,P17900,Q13510,O95470 5 +Regulation of mammary gland epithelial cell proliferation 0.8963191907839232 2.429118504394664 0.0151355842826459 1.0 0.109605346464645 2 Q9NQC3 1 +Protein targeting to membrane 0.5327196346742085 2.4053644596696993 0.016156343961619 1.0 0.1156134075963167 42 Q5BJH7,Q9Y3D6,Q5W0Z9,Q15041,P43307,O43681,Q9UNL2,P46379,Q15629,P56589,P27105,O60725,P40855 13 +Phospholipid metabolic process 0.4636367924070835 2.3920846235956694 0.016752979205264 1.0 0.1184996369519024 83 Q10713,Q86UL3,Q9NRA0,Q9H490,P37268,Q8WTV0,Q5H8A4,Q8WVX9,Q9UG56,Q8NCC3,Q96BW9,Q8NF37,Q8N2K0,Q9BTU6,Q9HCL2,Q9NUQ2,Q6IAN0,Q92604,Q8NHP8,O43292,O14735,Q86YN1,Q9BXW7,Q9NTJ5,Q9NPH0,Q99623,Q92643,O15269,Q96N66,P40939,Q8WWI5 31 +Diol metabolic process 0.8418164668143598 2.391638544642613 0.0167733520674218 1.0 0.1184996369519024 8 Q13510,P04062,Q9NRA0 3 +Diol biosynthetic process 0.8418164668143598 2.391638544642613 0.0167733520674218 1.0 0.1184996369519024 8 Q13510,P04062,Q9NRA0 3 +Phosphatidylglycerol metabolic process 0.7914404603993834 2.3907384555662445 0.0168145262456265 1.0 0.1186445342082719 10 Q8NF37,Q9HCL2,Q8NCC3,Q92604,Q99623,Q96BW9,P40939 7 +Protein transmembrane import into intracellular organelle 0.740832263023394 2.390411214968096 0.016829517699866 1.0 0.1186445342082719 13 O60830,O14925,Q99595,O43615,O96008 5 +Cytochrome complex assembly 0.7571879047873168 2.3861348434952 0.0170265067891328 1.0 0.1199062462239991 12 O75880,Q9Y2R0,Q69YU5,Q6DKK2,Q9BSK2,Q96I36,P53701,Q15070 8 +Negative regulation of secretion 0.6241136342282692 2.3848255299881616 0.0170872229169627 1.0 0.1202066263344471 23 P09601,Q8N5M9,Q16850,P00813,P40939,P04035 6 +Calcium ion import 0.6972941440039641 2.3822194261917313 0.017208640032942 1.0 0.1206780815797994 16 O75844,P21796,Q9NRA0 3 +Glycerophospholipid metabolic process 0.5058979981773796 2.37715067590259 0.0174469596598374 1.0 0.121708088612388 62 Q10713,Q86UL3,Q9UJZ1,Q9H490,Q8WTV0,Q5H8A4,Q8WVX9,Q9UG56,Q8IY17,Q8NCC3,Q96BW9,Q8NF37,Q8N2K0,Q9HCL2,Q9BTU6,Q9NUQ2,Q6IAN0,Q8TBX8,Q92604,Q96S52,O43292,O14735,Q9BXW7,Q9NTJ5,Q9NPH0,Q99623,Q92643,Q96N66,P40939,Q8WWI5 30 +Vacuole organization 0.5056541666433475 2.374855708757901 0.0175558115212417 1.0 0.1221138679065924 62 Q8N511,Q9P253,Q14108,P16615,Q9UMX0,P11117,Q9HC07,Q8NHS3,O75503,P04062,O95140,P53365,P50897,P10253,O14773,Q86Y82,P54802 17 +Glycolipid biosynthetic process 0.7868859135631676 2.3693740168401853 0.0178182243787918 1.0 0.1236499303867152 10 Q16739,Q99805,O43292,Q92643,Q5H8A4 5 +Proton transporting v type atpase complex assembly 0.8822703006462418 2.367635870280375 0.0179021453907637 1.0 0.1238448831346493 2 Q8N511 1 +Vacuolar proton transporting v type atpase complex assembly 0.8822703006462418 2.367635870280375 0.0179021453907637 1.0 0.1238448831346493 2 Q8N511 1 +Glycosphingolipid metabolic process 0.8015666273216829 2.363429388538985 0.0181066768117768 1.0 0.1251136487773911 9 Q99805,P04062,Q16739,P17900 4 +Regulation of steroid metabolic process 0.6678984916855644 2.3627081751212997 0.0181419490714023 1.0 0.1251136487773911 18 P05023,P22466,O76054,Q13510,P30536,Q9UBM7,Q12770,P16435 8 +Protein import into mitochondrial matrix 0.8010081218065416 2.3608707873578183 0.0182320819186576 1.0 0.1252162076044032 9 O96008,O60830,O14925,Q99595 4 +Negative regulation of insulin secretion involved in cellular response to glucose stimulus 0.8788985670131997 2.3528235400312356 0.0186314733734067 1.0 0.1273023155031026 2 Q8N5M9 1 +Cristae formation 0.7980941685212256 2.347508780140967 0.0188994277139462 1.0 0.128917351076121 9 Q16891,Q9Y512,O95202,Q6UXV4,Q9NX63,Q5XKP0 6 +Porphyrin containing compound metabolic process 0.6640912896707842 2.340556542458313 0.0192550225549295 1.0 0.1305162426428963 18 P09601,P22830,O00264,P30519,P30536 5 +G protein coupled opioid receptor signaling pathway 0.8760887889856622 2.3404632934406857 0.0192598315533536 1.0 0.1305162426428963 2 Q99720 1 +Regulation of calcium ion import 0.947175885679109 2.339681187620158 0.0193002073199286 1.0 0.1305162426428963 6 P21796 1 +Potassium ion export across plasma membrane 0.8741219443663917 2.3318021381907426 0.0197111025056671 1.0 0.1317042039911792 2 Q12959 1 +Regulation of potassium ion export across plasma membrane 0.8741219443663917 2.3318021381907426 0.0197111025056671 1.0 0.1317042039911792 2 Q12959 1 +Chromosome attachment to the nuclear envelope 0.872998033155377 2.3268495901201356 0.0199732719855902 1.0 0.1333220913381177 2 P02545 1 +Regulation of lysosomal lumen ph 0.9420448015252324 2.319593713717281 0.0203628662420423 1.0 0.135109546202185 6 Q8N511,P50897,Q9HC07 3 +Regulation of atp metabolic process 0.5917772133570409 2.3125809022382264 0.0207456925367859 1.0 0.1372391489386783 26 Q9BSK2,P14406,P30536,Q9NRA0 4 +Tetrapyrrole metabolic process 0.6201460807192571 2.302102527173661 0.0213293909469887 1.0 0.1388981548151997 22 P09601,P22830,O00264,P30519,P30536 5 +Sulfur compound transport 0.7708515357798433 2.2937223580894353 0.0218064516513933 1.0 0.1409459608615565 10 Q70HW3,Q9UBX3,Q8TB61 3 +Regulation of synaptic transmission dopaminergic 0.8651306546782751 2.292114414163544 0.0218990418528695 1.0 0.1409459608615565 2 O75955 1 +Positive regulation of toll like receptor 3 signaling pathway 0.8651306546782751 2.292114414163544 0.0218990418528695 1.0 0.1409459608615565 2 O75955 1 +Positive regulation of heterotypic cell cell adhesion 0.8651306546782751 2.292114414163544 0.0218990418528695 1.0 0.1409459608615565 2 O75955 1 +Folate transmembrane transport 0.8651306546782732 2.292114414163537 0.0218990418528699 1.0 0.1409459608615565 2 Q9H2D1 1 +Folic acid transport 0.8651306546782732 2.292114414163537 0.0218990418528699 1.0 0.1409459608615565 2 Q9H2D1 1 +Regulation of toll like receptor signaling pathway 0.7544263400051752 2.2913231734380224 0.0219447292961221 1.0 0.1409673489051088 11 P41440,O75955,Q9NPR9,Q9UMX0,P09429,Q9NQC3 6 +Negative regulation of receptor binding 0.8614779432424783 2.275947456074692 0.0228491546648093 1.0 0.1440168059475107 2 P16615 1 +Reactive nitrogen species metabolic process 0.6643975080664479 2.268023223327286 0.0233277912546894 1.0 0.1465972151085534 17 P30536,P16435,O43169 3 +Negative regulation of cell volume 0.8595110986232068 2.267231731505737 0.0233760733654162 1.0 0.1467620455158916 2 Q4KMQ2 1 +Sensory perception of light stimulus 0.6377148232738192 2.262756940345543 0.0236506766305821 1.0 0.1476350461000268 19 O43924,Q13432,O76024,P50897,Q6P4Q7 5 +Ligand gated ion channel signaling pathway 0.8583871874121907 2.2622480439321317 0.023682082487896 1.0 0.1476350461000268 2 P0DMN0 1 +Microglia differentiation 0.8583871874121864 2.2622480439321135 0.0236820824878971 1.0 0.1476350461000268 2 P04062 1 +Organic cation transport 0.8124671652415539 2.2619136737800214 0.0237027373837717 1.0 0.1476350461000268 8 Q9HC21,Q86VD7,O43772,Q70HW3,Q96QD8 5 +Positive regulation of hydrogen peroxide metabolic process 0.8581062096094356 2.261001750483038 0.0237591486661341 1.0 0.1476350461000268 2 P00403 1 +Regulation of hydrogen peroxide biosynthetic process 0.8581062096094356 2.261001750483038 0.0237591486661341 1.0 0.1476350461000268 2 P00403 1 +Negative regulation of systemic arterial blood pressure 0.8581062096094325 2.2610017504830235 0.023759148666135 1.0 0.1476350461000268 2 P42785 1 +Toll like receptor signaling pathway 0.6866636001004137 2.2575828252868497 0.0239716804048493 1.0 0.1486022760698575 15 P41440,O75955,Q9NPR9,P51812,Q9UMX0,P09429,Q9NQC3 7 +Glycerolipid metabolic process 0.4765357819435473 2.243260169097765 0.0248800422805768 1.0 0.1527460160306631 71 Q10713,Q86UL3,Q9UBV2,Q9UJZ1,Q53H12,Q9H490,Q8WTV0,Q5H8A4,Q8NCG7,Q8WVX9,Q9UG56,Q8IY17,Q8NCC3,Q96BW9,Q8NF37,Q8N2K0,Q9HCL2,Q9BTU6,Q9NUQ2,Q6IAN0,Q8TBX8,Q92604,Q96S52,O43292,O14735,Q9BXW7,Q9NTJ5,Q9NPH0,Q99623,Q92643,Q96N66,P40939,Q8WWI5 33 +Regulation of blood pressure 0.6265289196083421 2.240232987138911 0.0250758011694736 1.0 0.1536643248460837 20 P05023,P09601,P42892,P09493,Q9NZ08,P20020,P04179,P42785,Q9HB40 9 +L alpha amino acid transmembrane transport 0.7432814520271206 2.236886840799591 0.0252937368314425 1.0 0.1547149068136489 11 O75915,Q15758,O75746,Q9Y619,Q15041,P08195,Q9UJS0,P30825 8 +Protein localization to lysosome 0.6694819327030072 2.227684446333845 0.0259015649252729 1.0 0.1565621385810095 16 Q14108,Q9NQC3,P46934 3 +Hormone biosynthetic process 0.7540931406201415 2.2139239510983417 0.0268340108179752 1.0 0.1611602259775621 10 Q53GQ0,P30536,Q9UBM7,Q14849,P16435 5 +Regulation of deacetylase activity 0.9629110185189946 2.213604440516153 0.0268560015941572 1.0 0.1611602259775621 3 Q9NRA0 1 +Quaternary ammonium group transport 0.9623383923552564 2.2113823154030063 0.027009373426555 1.0 0.1616433274763705 3 O43772,Q96QD8 2 +Protein n linked glycosylation 0.6284839129956669 2.206798050104392 0.0273281713581468 1.0 0.1629255976107101 19 Q2TAA5,P61803,P46977,Q9BT22,Q9HC07,P04843,Q9H0U3,Q8TCJ2,Q13724,Q86YN1,O75352 11 +Cotranslational protein targeting to membrane 0.6772011773381138 2.205832310735737 0.0273957430714413 1.0 0.1630757335782129 15 P43307,Q15629 2 +Vitamin transmembrane transport 0.9116115377219264 2.1995213425356632 0.0278408732702142 1.0 0.1648995226401561 6 Q9H2D1,P04062,Q8WTV0,P38435 4 +Regulation of ion transport 0.4360373550348098 2.1993816203436207 0.0278507984143554 1.0 0.1648995226401561 87 Q15041,Q9UMX0,P0CG08,P21796,Q9NRA0,O76024,O75915,P22466,Q12959,P08183,Q4KMQ2,P46934,P05023,O75844,O14656,Q7L0J3,Q99623,P27105,P30536 19 +Glucosylceramide metabolic process 0.958560472702696 2.1967097106733893 0.0280411849000337 1.0 0.1657318699020642 3 P04062 1 +Dicarboxylic acid transport 0.6267457061852513 2.196219600531358 0.0280762291076586 1.0 0.1657917521840888 19 O75915,P41440,O14908,Q15758,O75746,Q15041,Q9H2D1,O60831,Q9UBX3,Q02978,Q9UJS0 11 +Sensory perception 0.5106727874666247 2.19559103249458 0.0281212286763699 1.0 0.1659102631571291 38 O43924,Q14108,Q13432,Q9Y6M9,O76024,P50897,Q6P4Q7 7 +Regulation of leukocyte degranulation 0.7943731414649658 2.1809529725223493 0.0291868950182008 1.0 0.1706843465255944 8 P09601,Q12846,Q9NRA0 3 +Cellular response to biotic stimulus 0.5065123255536957 2.1771119710343263 0.0294722140918384 1.0 0.1722015669720673 41 O75844,Q9UM00,O76024,Q86UE4,P30536,Q96A33,Q8WTV0,Q8IXJ6 8 +Response to interleukin 12 0.8384377634166846 2.173394906723855 0.0297506078494553 1.0 0.1734688018376161 2 Q08722 1 +Neutral lipid catabolic process 0.837875807811179 2.170881334740018 0.0299401436144153 1.0 0.1734688018376161 2 Q8NCG7 1 +Er nucleus signaling pathway 0.6703831143633943 2.1683488811191634 0.0301321519339698 1.0 0.1734688018376161 15 P57088,P16615,Q9UM00,O76024,Q15363,Q96A33 6 +Lipoprotein biosynthetic process 0.6347192892941235 2.16767460800592 0.0301834527416617 1.0 0.1736135505581324 18 Q16739,P04062,Q8IUH4,O43292,Q5W0Z9,Q92643,Q5H8A4 7 +Purine containing compound transmembrane transport 0.7437064900783484 2.1640904360526303 0.0304574093758283 1.0 0.1747362581001184 10 P05141,O43808,Q8TB61,Q86VD7,P12236,P12235 6 +Decidualization 0.835627985389147 2.160821265671328 0.0307091487081558 1.0 0.1759515987736574 2 P35613 1 +Regulation of appetite 0.8342230963753766 2.154529035884601 0.0311987074378132 1.0 0.1780680943384625 2 P80303 1 +Regulation of response to food 0.8342230963753766 2.154529035884601 0.0311987074378132 1.0 0.1780680943384625 2 P80303 1 +Negative regulation of response to food 0.8342230963753766 2.154529035884601 0.0311987074378132 1.0 0.1780680943384625 2 P80303 1 +Sphingoid metabolic process 0.8993816739171856 2.15082271320343 0.0314901956276736 1.0 0.1791173093180923 6 Q06136,P04062,Q9NRA0 3 +Oxaloacetate transport 0.8319752739533485 2.144453993887494 0.0319965279324456 1.0 0.1807440064020149 2 Q9UBX3 1 +Succinate transmembrane transport 0.8319752739533485 2.144453993887494 0.0319965279324456 1.0 0.1807440064020149 2 Q9UBX3 1 +Mitochondrial protein catabolic process 0.8305703849395817 2.138152434548061 0.0325043734223586 1.0 0.1814558912359015 2 Q9UG56 1 +Anatomical structure maturation 0.5036026967144569 2.1363338242106433 0.0326522137729816 1.0 0.1819937040696758 38 Q8N2A8,Q9NZJ7,P22466,P04062,Q8IXJ6 5 +Lysosomal lumen acidification 0.9476380814170496 2.130738446760676 0.0331106958226037 1.0 0.183203620886656 4 Q8N511,P50897 2 +Cellular response to chemical stress 0.4276018658930133 2.1304717632819576 0.0331326845973267 1.0 0.183203620886656 90 O75915,P09601,P16615,Q9UMX0,Q8TED1,P04062,Q86Y07,Q7Z2K6,Q07820,Q8N0U8,Q12846,O95202,P00374,Q6NUK1,P30536,Q99720,Q8IXJ6 17 +Cellular ion homeostasis 0.4220364731958418 2.130327594081247 0.0331445769417781 1.0 0.183203620886656 96 Q9Y3D6,Q16891,Q8WWC4,P0CG08,Q93050,P35670,O76024,Q8N511,Q96TC7,Q92544,O75503,Q96AQ8,P50897,O95202,Q96A33,Q92581,O75880,P09601,P16615,P51572,Q9Y6M7,Q9UM00,O43819,P05023,P06576,Q9HC07,P09429,Q7L0J3,Q9Y639,P51790,O60826,Q9HD20,P05067 33 +Ornithine transport 0.8283225625175552 2.128062512335844 0.033331900942799 1.0 0.1836289741509334 2 P30825 1 +Regulated exocytosis 0.5024989341127742 2.127047433185363 0.0334161422669845 1.0 0.183940799658215 38 P09601,Q9P253,P11279,P16615,Q9BRK5,Q9NRA0,Q7L0J3,O43760,Q12846 9 +Antigen processing and presentation of peptide antigen via mhc class i 0.7041651742770747 2.1195942552069584 0.0340402773717569 1.0 0.1862977351225679 12 P01889,Q9NZ08,Q9Y6B6,P10321,Q03518,P14735,Q9UIQ6,Q03519 8 +Positive regulation of toll like receptor 9 signaling pathway 0.8260747400955227 2.117963481477059 0.0341781605717095 1.0 0.186439064430104 2 Q9NQC3 1 +Toll like receptor 9 signaling pathway 0.8260747400955227 2.117963481477059 0.0341781605717095 1.0 0.186439064430104 2 Q9NQC3 1 +Regulation of toll like receptor 9 signaling pathway 0.8260747400955227 2.117963481477059 0.0341781605717095 1.0 0.186439064430104 2 Q9NQC3 1 +Olfactory behavior 0.8249508288845113 2.112910562265973 0.0346084236640973 1.0 0.1879428153057735 2 O76024 1 +Chemosensory behavior 0.8249508288845113 2.112910562265973 0.0346084236640973 1.0 0.1879428153057735 2 O76024 1 +Vesicle docking 0.6127990180146364 2.1108681775196616 0.0347836440081512 1.0 0.1881100322544374 19 Q9P253,Q9UEU0,O60499,O15400,Q9UNK0,Q12846,P61026,Q86Y82 8 +Excitatory synapse assembly 0.8243888732790066 2.11038325385737 0.0348253577120947 1.0 0.1881100322544374 2 O15031 1 +Gpi anchor metabolic process 0.832719637013458 2.1073629848569153 0.0350861275628044 1.0 0.1889143842479481 7 Q92643,O43292,Q5H8A4 3 +Tail anchored membrane protein insertion into er membrane 0.7304017394725787 2.099837177646149 0.0357431665998198 1.0 0.1918312691304844 10 Q9P0I2,Q9NPA0,Q8N4V1,O43681,P46379,Q5J8M3 6 +Antigen processing and presentation of endogenous peptide antigen 0.776008439475982 2.0980151569506926 0.0359038064697703 1.0 0.1919781013597834 8 P01889,Q9NZ08,P10321,Q03518,P14735,Q03519 6 +Organelle fusion 0.4840124968095662 2.097218141669869 0.0359742692609037 1.0 0.192141863508278 56 Q9Y3D6,O60499,Q9UNK0,Q9UJZ1,Q12846,Q9NX63,Q969M3,Q9P253,O95140,Q8TB36,Q9BZG1,Q86Y82,Q9UEU0,O15400,Q8N2A8,Q9BSR8,Q12981,Q9H270,Q99536,Q5SQN1,Q9Y6C9,O60313 22 +Export from cell 0.3888831351994696 2.0948955561274647 0.0361802779926954 1.0 0.1929324920203429 159 Q9UL25,Q9UBV2,O15126,Q9NRA0,P35670,Q16850,Q12846,Q8TBQ9,Q9H4A6,Q96KC8,P04035,Q86YV9,Q9P253,P11279,P22466,P27824,Q12959,Q9NZ43,P53367,P49755,Q8N183,P50897,O43760,P08183,P09601,Q4KMQ2,Q9UEU0,P16615,Q9BRK5,Q5T9L3,O00255,O95563,P05023,Q8N5M9,Q7L0J3,Q5SQN1,P40939,Q96PC5 38 +Export across plasma membrane 0.7281088740990359 2.088716688038237 0.0367332337357169 1.0 0.1947885820806343 10 P05023,Q4KMQ2,Q12959,P35670,P33527,P08183 6 +Glycosylceramide metabolic process 0.9362920800015566 2.086989003616427 0.0368891285665595 1.0 0.1953040179876324 4 P04062 1 +Sodium ion transmembrane transport 0.5639462953669918 2.079771802156546 0.0375464686353042 1.0 0.1984120013351173 25 P05023,Q4KMQ2,Q12959,P46934,Q9Y6M7,Q6P4Q7,P27105,Q92581 8 +Regulation of systemic arterial blood pressure 0.7688537192960875 2.0654955977860507 0.0388761316387176 1.0 0.2038775855442598 8 P42892,P09493,P42785 3 +C21 steroid hormone biosynthetic process 0.9248334676412868 2.0648061413180767 0.0389413465546417 1.0 0.2040587884418432 3 Q14849 1 +Pattern recognition receptor signaling pathway 0.510480802956931 2.0574058060489793 0.0396472071257418 1.0 0.2069832204249557 33 P41440,O43657,O75955,Q9NPR9,Q9UMX0,P51812,Q14254,P09429,Q9H078,Q9NQC3,Q99623 11 +Vitamin d metabolic process 0.921921420129658 2.0533415127607455 0.0400394673986115 1.0 0.2084448475747834 3 P04062 1 +Positive regulation of nitric oxide synthase activity 0.9211069336065628 2.050132791711724 0.0403514742237363 1.0 0.2091793065668551 3 Q8WTV0 1 +Manganese ion transport 0.9208278545615212 2.0490331299172904 0.0404588754504477 1.0 0.209218320782672 3 Q9HC07 1 +Manganese ion transmembrane transport 0.9208278545615212 2.0490331299172904 0.0404588754504477 1.0 0.209218320782672 3 Q9HC07 1 +Homologous chromosome pairing at meiosis 0.7339720747998988 2.048053925374783 0.0405547158241392 1.0 0.209218320782672 9 Q92791,Q9BTX1,P46379 3 +Negative regulation of interferon gamma production 0.8103399831413313 2.0470186221008575 0.0406562561557022 1.0 0.2094174804305169 2 P09429 1 +Positive regulation of trophoblast cell migration 0.8103399831413216 2.0470186221008126 0.0406562561557066 1.0 0.2094174804305169 2 P36896 1 +Epithelial cell differentiation involved in prostate gland development 0.9243179321130092 2.0406176821404833 0.0412888432307849 1.0 0.2113671166929799 4 P07602 1 +Generation of precursor metabolites and energy 0.3769890810939987 2.0399675501164536 0.0413535578532131 1.0 0.2114115065464066 188 P14406,Q9NRA0,O75964,P13073,P22830,P15954,P12235,O14949,O43676,Q9Y6M9,Q6KCM7,P08574,Q16134,Q9UDW1,P21912,O15121,O95168,P51970,Q9BRR6,P56385,Q9H3K2,O96000,P04062,O75947,Q9BSK2,P03886,P10253,Q15070,O75380,P24539,Q9UJS0,P16435,P00403,Q13423,P49748,P22695,Q9P0J0,P52789,Q99623,P14735,P06576,P05067,Q9Y375 43 +Metal ion export 0.7180757875786752 2.039892348032788 0.0413610490643758 1.0 0.2114115065464066 10 P05023,O95202,Q12959,P35670 4 +Endoplasmic reticulum unfolded protein response 0.579634969002106 2.0394599026372378 0.0414041491674745 1.0 0.2114693881116987 22 Q6NTF9,P57088,Q9Y4P3,Q7Z2K6,O76024,Q96HY6,Q15363,Q9BUN8 8 +Long chain fatty acyl coa biosynthetic process 0.7630618931820344 2.039085855706435 0.0414414596007821 1.0 0.2114976331619672 8 Q6Y1H2,Q9UKU0,Q53GQ0 3 +Branched chain amino acid transport 0.8069682495082855 2.0317597490754364 0.0421779838660631 1.0 0.2134198630575761 2 Q9H2J7 1 +Leucine transport 0.8069682495082855 2.0317597490754364 0.0421779838660631 1.0 0.2134198630575761 2 Q9H2J7 1 +Aromatic amino acid transport 0.8069682495082815 2.0317597490754187 0.0421779838660649 1.0 0.2134198630575761 2 P30825 1 +Negative regulation of autophagy 0.5457762467204195 2.0308809340344665 0.0422670743065192 1.0 0.2134198630575761 27 P09601,P10619,O15118,P30536,Q8IXJ6 5 +Fatty acid elongation 0.9139966273187188 2.0220822611946367 0.0431678542672167 1.0 0.2164448496475336 3 Q6Y1H2,Q9P035 2 +Inorganic anion transmembrane transport 0.6999760729112022 2.022052960047346 0.0431708809178557 1.0 0.2164448496475336 11 Q4KMQ2,Q9UBX3,P51790,Q02978,Q9UHG3 5 +Regulation of oxidoreductase activity 0.6104254458503106 2.0220111515078076 0.0431751998252147 1.0 0.2164448496475336 18 Q9NRA0,P00374,Q15070,Q8WTV0,P16435 5 +Regulation of secretion 0.4059455987651609 2.020911480054574 0.0432889293014167 1.0 0.2166073868428031 103 Q9UL25,Q9NRA0,Q16850,Q12846,Q9H4A6,Q96KC8,P04035,Q9P253,P11279,P22466,P53367,P09601,P16615,Q5T9L3,O95563,Q8N5M9,Q7L0J3,P40939,P00813 19 +Peptide catabolic process 0.6989753429351776 2.017026431088722 0.0436927551134944 1.0 0.2181359979597191 11 P09960,P55786,O14773 3 +Ceramide transport 0.8887255026477473 2.0153956705303786 0.0438632077167788 1.0 0.2186589118765269 5 P08183,P07602 2 +Positive regulation of mitochondrial translation 0.7269214445784076 2.014496353520951 0.043957447331498 1.0 0.2189646796340716 9 O95900,Q9Y2R0,Q567V2 3 +Leukocyte degranulation 0.6822718521330342 2.007103039641839 0.0447386926507227 1.0 0.2218599102761249 12 P09601,Q12846,Q9NRA0 3 +Prostate gland development 0.8089274371575469 2.005515752935236 0.0449079383721415 1.0 0.2222024757372507 7 P07602 1 +Amyloid precursor protein metabolic process 0.5878209310644211 1.99779852774179 0.0457385070348557 1.0 0.2248131404799806 20 O95197,Q12959,Q9NQC3,Q15392,Q9Y287 5 +Adp transport 0.8838582677165345 1.9960124045218912 0.0459325726016865 1.0 0.2255950337005345 5 Q86VD7,O43808,P12236,P12235 4 +Multi multicellular organism process 0.5337412982820563 1.985729890461472 0.0470633241838382 1.0 0.2292872785091096 28 Q9BQE5,P35613,P36896,Q9NRA0,Q96QD8 5 +Regulation of regulated secretory pathway 0.5714401413519837 1.9853655542247188 0.0471038154359437 1.0 0.2293166728062954 22 P09601,Q9P253,P16615,Q9NRA0,Q12846 5 +Stem cell proliferation 0.6920563260015684 1.9821972399212835 0.0474571694826158 1.0 0.2305374610609524 11 P08183 1 +Regulation of protein exit from endoplasmic reticulum 0.8035128251311449 1.982185341932739 0.0474585006241179 1.0 0.2305374610609524 7 Q9GZP9,P51572,Q92544,Q9NR31 4 +Antigen processing and presentation of peptide antigen 0.6471132646068009 1.9817776506086997 0.0475041319143818 1.0 0.2305866212515777 14 P04439,P01889,Q99538,Q9NZ08,Q9Y6B6,P10321,Q03518,P14735,Q9UIQ6,Q03519 10 +Small molecule biosynthetic process 0.3847602817462814 1.980927560623884 0.0475993978087345 1.0 0.2305866212515777 153 Q8NI60,P53007,P09960,Q9NRA0,Q16850,P37268,Q9UBM7,P04035,P48449,Q8NCG7,A1L0T0,Q53GQ0,Q9NZ01,Q15392,P00374,O76062,O15121,Q12770,Q14849,O95864,Q9P035,O76054,Q9H7Z7,P04062,Q92604,Q9BV57,Q6Y1H2,O00767,Q13510,Q9UJS0,P16435,P49748,O14880,Q92520,Q96SU4,Q13126,Q99735,Q15800,Q9UBX3,Q9BXW6,Q14739,O15269,P00813 43 +Mitochondrial atp synthesis coupled proton transport 0.7054029929621948 1.977843945879886 0.0479463141395655 1.0 0.2311611138835158 10 P56385,P36542,Q9UJZ1,O75947,O75964,P06576,P24539 7 +Negative regulation of protein secretion 0.7050234253347385 1.975979035126082 0.048157151709417 1.0 0.2315649166374063 10 Q16850,P40939,Q8N5M9,P04035 4 +Atp biosynthetic process 0.5903578011603916 1.9717612077145212 0.0486368726730483 1.0 0.2323715864089201 19 P56385,P56134,P36542,Q9NRA0,Q9UJZ1,O75947,O75964,P06576,Q9UJS0,P24539,P00403 11 +Positive regulation of blood circulation 0.8775087434107268 1.9706721759938368 0.0487613850865296 1.0 0.2324548837756837 5 P05023,P00813,P16615 3 +Maintenance of protein location in cell 0.5610919862975102 1.9677768487072071 0.0490937190902567 1.0 0.2338716539339001 23 P24390,O94901,P30536,O43292,Q9UH99,O15258,Q9H4A6,Q96RL7 8 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.5360807349264947 1.960639011754028 0.0499211481538508 1.0 0.2369652218001978 27 P24390,Q9NZ43,Q12981,Q9Y282,Q12893,Q9P2W9,Q969X5,O15258,Q9H4A6 9 +Phosphatidylethanolamine metabolic process 0.9035467259743332 1.9597024191925545 0.050030582248095 1.0 0.2371139909152659 4 Q8NCC3 1 +Tetrapyrrole catabolic process 0.9026973760011172 1.9563811235788937 0.0504202741343027 1.0 0.2379884607618005 4 P30519 1 +Phospholipid transport 0.6216857423616992 1.9554491313169624 0.0505300819017917 1.0 0.2379884607618005 16 Q14108,Q8WTV0 2 +Myeloid leukocyte mediated immunity 0.6101652980295014 1.9518680015768408 0.0509538781761955 1.0 0.2395679337532967 17 P09601,Q8N5M9,Q9NRA0 3 +Amino acid import 0.7000032535396224 1.9512784436649024 0.0510239319133125 1.0 0.2395679337532967 10 O75915,Q15041,Q9H9B4,P08195,Q96NB2,P30825 6 +Sphingosine biosynthetic process 0.8725441458032255 1.9508169042760184 0.0510788302230056 1.0 0.2395679337532967 5 P04062,Q9NRA0 2 +Protein targeting to vacuole 0.6099335754744702 1.9504926768185176 0.0511174253838739 1.0 0.2395679337532967 17 P13473,Q14108,P46934 3 +Protein retention in er lumen 0.8954468802698161 1.9485786874193176 0.0513457593727006 1.0 0.2402534063427095 3 P24390,O43292 2 +Maintenance of protein localization in endoplasmic reticulum 0.8954468802698161 1.9485786874193176 0.0513457593727006 1.0 0.2402534063427095 3 P24390,O43292 2 +Amide transport 0.4784861819233098 1.9466550777108436 0.0515761006615866 1.0 0.2408694385283223 43 P41440,Q9NZJ7,P22466,P07602,Q9H2D1,O95563,Q8N5M9,Q8N183,Q12846,P08183,P40939,Q03519 12 +Vacuolar acidification 0.7126483545307258 1.946186547828908 0.0516323352243952 1.0 0.2409629669834154 9 Q8N511,O75503,P50897 3 +Cellular response to topologically incorrect protein 0.4811455600222791 1.945508730970162 0.0517137799286375 1.0 0.2411739351261969 38 Q6NTF9,Q9GZP9,P57088,P48723,O14656,Q9Y4P3,O76024,Q96HY6,Q7Z2K6,Q9NXW2,P46379,Q15363,Q9BUN8 13 +Neurofilament cytoskeleton organization 0.7878617589210438 1.944929045734193 0.0517835186484256 1.0 0.241330053645149 2 P07196 1 +Iron ion transport 0.7121760189456644 1.9439174270996051 0.0519054093604645 1.0 0.2417288308564669 9 Q8N4V1 1 +Response to corticosterone 0.7872998033155366 1.9423660568198864 0.0520928013983899 1.0 0.2422624691169006 2 P07196 1 +Regulation of pattern recognition receptor signaling pathway 0.5571413092472892 1.9409681721041472 0.0522621380469603 1.0 0.2425415123448542 23 P41440,O43657,O75955,Q9NPR9,Q9UMX0,Q14254,P09429,Q9NQC3 8 +Polyol biosynthetic process 0.6691496792179684 1.9390034747121725 0.052500915057895 1.0 0.2430045798737779 12 Q13510,P04062,Q9NRA0 3 +Erad pathway 0.4782926471605744 1.9389454830316808 0.0525079768382408 1.0 0.2430045798737779 42 Q9GZP9,Q6NTF9,P27824,Q9UMX0,Q96A33,P51572,Q9BUN8,O76024,Q8TCT9,O14656,Q8TCJ2,P46379,Q9UBU6,O75477,O14967,Q9UBV2 16 +Protein localization to vacuole 0.5567346655330999 1.9382043159480131 0.0525983004108365 1.0 0.2430845064125815 23 P13473,Q14108,Q9NQC3,P46934 4 +Regulation of mitochondrial gene expression 0.6541702033691793 1.9376226937659975 0.0526692716970118 1.0 0.2431710175860179 13 O95900,Q9Y2R0,Q567V2 3 +Regulation of protein deacetylation 0.6185770836017821 1.937452136516319 0.0526900987767149 1.0 0.2431710175860179 16 Q9NRA0 1 +Bone growth 0.8912673240750135 1.9319539645290036 0.0533651881626067 1.0 0.2445577612247642 3 O75844 1 +Growth plate cartilage development 0.8912673240750135 1.9319539645290036 0.0533651881626067 1.0 0.2445577612247642 3 O75844 1 +Regulation of mast cell activation 0.8964440344763671 1.9318981405243785 0.0533720793505021 1.0 0.2445577612247642 4 Q9NRA0 1 +Regulation of mast cell activation involved in immune response 0.8964440344763671 1.9318981405243785 0.0533720793505021 1.0 0.2445577612247642 4 Q9NRA0 1 +Cellular hormone metabolic process 0.5839615551867213 1.9317140879262165 0.0533948049676307 1.0 0.2445577612247642 19 P42892,Q53GQ0,O95470,P30536,Q14849,Q9HB40 6 +Regulation of reactive oxygen species metabolic process 0.487540541988254 1.9298717795754752 0.0536227268523588 1.0 0.2452640874243628 34 Q9NRA0,Q9BSK2,P00374,P30536,P42785,Q8IXJ6 6 +Prostate gland growth 0.8899509333040507 1.9267131362770569 0.0540153898588542 1.0 0.2465559202942814 3 P07602 1 +Establishment of protein localization to mitochondrial membrane 0.6271205877604994 1.92670577062811 0.0540163083078981 1.0 0.2465559202942814 15 Q8WWC4,Q9NS69,Q9P0J0,Q9Y5J6,Q9Y512,Q53H12,Q15070 7 +Steroid hormone biosynthetic process 0.7375035751059259 1.9216483761687355 0.0546500170953911 1.0 0.2477492260012455 8 P30536,Q14849,Q53GQ0 3 +Antigen processing and presentation 0.5302443201037903 1.918095679440218 0.0550988802190715 1.0 0.2487231277822432 27 P04439,P14735,P61020,P01889,Q9NVJ2,P04062,Q99538,Q9NZ08,Q9BYJ9,Q9Y6B6,P10321,P61026,Q03518,Q15286,Q9BZG1,Q9UIQ6,Q03519 17 +Ph reduction 0.6504509616486928 1.9176644325722076 0.0551535744053066 1.0 0.2487231277822432 13 Q8N511,P0CG08,Q93050,O75503,P50897 5 +Regulation of oxidative phosphorylation 0.7881108582267058 1.915518517934256 0.0554264098546781 1.0 0.2489493074097918 7 P14406 1 +Transmembrane receptor protein tyrosine phosphatase signaling pathway 0.7813992694577068 1.915424035534553 0.0554384483217598 1.0 0.2489493074097918 2 P10586 1 +Calcium ion transport 0.456428702351384 1.9123606528886208 0.0558299511581148 1.0 0.2503694912110877 63 P16615,Q9UMX0,Q9HC07,Q6KCM7,P21796,Q9NRA0,O75844,O76024,P30536,Q9UM00 10 +Secretion 0.3686007434838899 1.911107532313547 0.0559907633831224 1.0 0.2509146578710161 171 Q9UL25,Q9NRA0,P35670,Q16850,Q12846,Q8TBQ9,Q9H4A6,Q96KC8,P04035,Q9P253,P11279,P22466,P27824,P55327,Q9NZ43,P53367,P50897,O43760,Q13505,P09601,P16615,Q9BRK5,Q5T9L3,Q9H7Z7,O95563,P00403,Q8N5M9,Q7L0J3,Q5SQN1,P40939,P00813,Q96PC5 32 +Nucleobase transport 0.8833614390106812 1.9004454137020108 0.0573746919947313 1.0 0.2535382305610481 3 Q9Y277,P12235 2 +Mitochondrial adp transmembrane transport 0.883361439010681 1.900445413702009 0.0573746919947315 1.0 0.2535382305610481 3 P12236,P12235 2 +Potassium ion transport 0.5272452296428316 1.8961587742825503 0.0579390526876459 1.0 0.255016134680082 27 P05023,P22466,Q12959,P46934,Q96ER9,Q92581 6 +Positive regulation of oxidoreductase activity 0.7019976710315197 1.894888242026491 0.0581072092270438 1.0 0.2553522704007242 9 Q8WTV0,P00374 2 +Granulocyte differentiation 0.7316723940677909 1.894653031000656 0.058138384145139 1.0 0.2553522704007242 8 Q14739,Q8N5M9 2 +Proteoglycan metabolic process 0.7316723156486656 1.8946526674641349 0.0581384323390989 1.0 0.2553522704007242 8 Q8NCH0,Q8N6G5,Q99805 3 +Proteoglycan biosynthetic process 0.7829648421912203 1.893145521825484 0.0583385198523778 1.0 0.2553522704007242 7 Q8NCH0,Q8N6G5,Q99805 3 +Regulation of alcohol biosynthetic process 0.8354680053333077 1.892255055779321 0.0584570060542739 1.0 0.2553522704007242 6 O76054,Q9UBM7,Q12770,P16435 4 +Regulation of cholesterol biosynthetic process 0.8354680053333077 1.892255055779321 0.0584570060542739 1.0 0.2553522704007242 6 O76054,Q9UBM7,Q12770,P16435 4 +Positive regulation of heart rate 0.8811129848229351 1.891469720688579 0.0585616692525827 1.0 0.2554317485389448 3 P00813,P16615 2 +Carbohydrate derivative biosynthetic process 0.3658732491386732 1.8914010675628383 0.0585708261863906 1.0 0.2554317485389448 173 Q92542,Q13232,Q16739,Q9NRA0,Q8WVC6,O15118,O75964,Q9H490,Q9H4A6,Q9UKU0,Q5H8A4,Q8NCH0,Q9UMR5,Q53GQ0,Q10472,P50897,Q9NZ01,Q99805,Q2TAA5,O95563,Q6Y1H2,O43292,Q86YN1,Q9BT22,P24539,P00403,Q8N4A0,O43505,Q8TB61,Q9UIJ7,P46977,Q9HC07,Q13126,Q7LGA3,Q6ZXV5,Q8N6G5,Q92643,P00813,Q9Y287 39 +Regulation of myeloid leukocyte mediated immunity 0.6737756396356122 1.8895423249024828 0.0588191970258824 1.0 0.2559898884375231 11 P09601,Q9NRA0 2 +Macromolecule deacylation 0.4712590883571489 1.8888544568932717 0.0589113334537634 1.0 0.2559898884375231 44 P49354,P50897,Q9NRA0,Q8IXJ6 4 +Skin development 0.4711177116838788 1.8875896594073625 0.059081059364489 1.0 0.2559898884375231 44 P36896,P22466,O75844,P04062,Q15392,Q13510 6 +Detection of other organism 0.7752177577971257 1.8871400300205947 0.0591414938140233 1.0 0.2559898884375231 2 P01889 1 +Protection from natural killer cell mediated cytotoxicity 0.7752177577971257 1.8871400300205947 0.0591414938140233 1.0 0.2559898884375231 2 P01889 1 +Phospholipid biosynthetic process 0.4524932088482248 1.88627746857331 0.059257573878493 1.0 0.2562437648871808 64 Q10713,Q9NRA0,Q9H490,Q5H8A4,Q8WVX9,Q9UG56,Q96BW9,Q8NF37,Q9BTU6,Q9HCL2,Q9NUQ2,Q6IAN0,Q92604,O43292,O14735,Q86YN1,Q9BXW7,Q9NTJ5,Q9NPH0,O15269,Q96N66,Q92643,Q8WWI5 23 +Nuclear pore complex assembly 0.6995145276658048 1.8828888828533008 0.0597154281351928 1.0 0.2577212543707576 9 Q9BTX1 1 +Negative regulation of t cell apoptotic process 0.8788720559800389 1.8825177264509991 0.0597657553680155 1.0 0.2577712909748175 3 P00813 1 +Positive regulation of mitophagy 0.8836097835254351 1.881487115492488 0.059905686344029 1.0 0.2580403512100409 4 P27544,P12235,P21796 3 +Response to oxidative stress 0.3904859192686779 1.8792093632250797 0.0602159116518561 1.0 0.2590413006096332 109 O43169,Q9UMX0,Q07820,P30519,Q8N0U8,P23246,Q12846,Q6NUK1,Q99720,O75915,P09493,Q16134,Q15165,Q9UL15,Q15392,P00374,O95168,P09601,P16615,P04062,Q96T60,Q8TED1,Q7Z2K6,O14656,P04179,P05067,Q86Y07,Q8IXJ6 28 +Positive regulation of lipid biosynthetic process 0.6431074346182456 1.878132981068351 0.0603629755134198 1.0 0.2591741930378128 13 Q92604,Q8WTV0,Q9NRA0,P16435 4 +Regulation of translation initiation in response to endoplasmic reticulum stress 0.7732509131778479 1.8781281499859797 0.0603636362447197 1.0 0.2591741930378128 2 Q15363 1 +Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation 0.7732509131778479 1.8781281499859797 0.0603636362447197 1.0 0.2591741930378128 2 Q15363 1 +Nuclear envelope organization 0.4882891424227784 1.8776659867733656 0.0604268725174979 1.0 0.2592390294491438 33 Q5JTV8,Q86XL3,P50402,P20700,O94901,O75844,Q9UH99,P02545,Q9BTV4,Q8IXJ6 10 +Protein catabolic process in the vacuole 0.7279031462971072 1.8771641511412125 0.0604955992087934 1.0 0.2592390294491438 8 Q8N511,P13473,P04062,O14773,Q96RL7 5 +Lysosomal protein catabolic process 0.7279031462971072 1.8771641511412125 0.0604955992087934 1.0 0.2592390294491438 8 Q8N511,P13473,P04062,O14773,Q96RL7 5 +Ubiquitin dependent erad pathway 0.4734585870509451 1.8764658556114664 0.0605913389832684 1.0 0.2594822142430188 37 Q9GZP9,Q6NTF9,P27824,Q9UMX0,Q96A33,P51572,Q9BUN8,O76024,Q8TCJ2,P46379,Q9UBU6,O75477,O14967,Q9UBV2 14 +Ceramide catabolic process 0.7784703540486865 1.873565275004037 0.0609903679647585 1.0 0.260334335881897 7 Q13510,P04062 2 +Protein exit from endoplasmic reticulum 0.554363393672242 1.8716024293978943 0.0612616270632642 1.0 0.260842052531045 22 Q9GZP9,Q92544,Q9NR31,P49257,O15260,P51572,Q8TCT9,Q9Y6B6,Q9BUN8,Q9UBV2 10 +Retinal metabolic process 0.770441135150319 1.865243799101024 0.0621472388122086 1.0 0.2636009396400564 2 Q8NBN7 1 +Midbrain development 0.5722842605287933 1.858150027716777 0.0631477121724071 1.0 0.2655974089942101 19 Q8IXJ6,Q5T9L3,O14949 3 +Regulation of mitochondrial fusion 0.84926839246472 1.8572464070978432 0.063276105317185 1.0 0.2655974089942101 5 Q8N2A8,Q99536 2 +Regulation of reactive oxygen species biosynthetic process 0.6941581737046928 1.8569549017093168 0.0633175705671766 1.0 0.2655974089942101 9 Q9BSK2,Q9NRA0,P51790,P00403 4 +Nitrogen compound transport 0.3568126895414815 1.8565756409268073 0.063371552211811 1.0 0.2655974089942101 649 Q9GZP9,Q14108,O60830,Q9NS69,Q8WWC4,Q99595,Q13432,O15126,Q12893,Q9H2J7,Q8TCT9,Q53H12,Q16850,Q03518,Q15629,P56589,Q8TEM1,Q86YV9,P24390,P22466,P43307,Q8N4H5,Q9Y282,P49257,O95140,P49755,P53365,Q9Y6B6,P50897,P08183,Q7Z3B4,P40855,Q9UEU0,Q9BVK6,Q5T9L3,P22626,O43772,O00255,Q9BSK2,Q9P2W9,O60725,Q9BUN8,Q96QD8,Q9BTX1,P07602,Q8TB61,Q9H2D1,Q8N5M9,O95070,O15173,Q9HD20,P27105,P30536,P40939,Q9NZJ7,Q15041,Q9HC21,Q86VD7,O60499,Q96KC8,Q5BJH7,Q9P253,O14925,Q6KCM7,P55786,P41208,O75955,Q9Y277,O15127,P46934,Q15070,Q15363,Q9P0J0,Q9Y5J6,P12236,P02545,Q5W0Z9,P10619,Q10713,Q15005,Q9Y5M8,P13473,Q969Q5,Q07820,Q12846,P46379,Q9H4A6,Q6P4A7,Q96RL7,P50402,P27824,O96008,Q08722,Q8TB36,P30825,O95563,O15400,A6NIH7,O43808,Q7L0J3,Q9Y3E0,Q99623,Q96PC5,Q9UL25,Q9NR31,P0CG08,O43615,O15260,Q9Y512,Q9UNL2,Q8TBQ9,Q6NUK1,P12235,P04035,O75915,P05141,Q92544,Q9NZ43,O14678,O43681,P53367,Q8N183,Q96NB2,Q86Y82,O75381,Q9UPR3,P51572,O15504,Q9UJS0,Q9H0R1,P41440,Q86V81,O14656,O60826,Q03519,Q9Y3A6,Q9UBV2 137 +Mitochondrial electron transport ubiquinol to cytochrome c 0.8484114190919857 1.8537864573845573 0.063769716725579 1.0 0.2665863741367432 5 Q9UDW1,O14949 2 +Chemical homeostasis 0.367095247954774 1.852300862618488 0.0639826319236149 1.0 0.266794746523595 200 Q16891,Q16739,Q96CP7,P0CG08,Q93050,O15260,P35670,O15118,P30519,O76024,Q12846,Q8WTV0,O15254,Q8N511,Q92544,O75503,Q8N183,Q96AQ8,P50897,O95202,Q6P4Q7,Q96A33,P42785,Q92581,Q8NF37,P09601,Q9P035,Q9HCL2,Q5BJF2,P16615,O95563,P04062,P51572,Q9Y6M7,Q9UM00,P05023,P61916,P06576,Q9HC07,Q8N5M9,Q9NQC3,P52789,Q7L0J3,P04179,P51790,Q9Y6C9,O60826,Q9HD20,P05067,P30536 50 +Cell recognition 0.5315320117025905 1.851702894543927 0.0640684981493029 1.0 0.2669855073159743 25 P35613,Q12959,Q8WTV0,Q9NQC3,P45880,Q9Y639,P05067,O14967 8 +Positive regulation of chemokine c x c motif ligand 2 production 0.7673503793200305 1.8510572740801272 0.0641613139039245 1.0 0.2670366282221665 2 P09429 1 +Chemokine c x c motif ligand 2 production 0.7673503793200305 1.8510572740801272 0.0641613139039245 1.0 0.2670366282221665 2 P09429 1 +Synaptic membrane adhesion 0.7670694015172732 1.8497668834083707 0.0643471558727832 1.0 0.267476778471813 2 P10586 1 +Negative regulation of amyloid precursor protein biosynthetic process 0.7667884237145156 1.8484763756902152 0.0645334588791455 1.0 0.2679165120653234 2 Q9Y287 1 +Vascular transport 0.622954100455567 1.848067674736391 0.0645925533668225 1.0 0.2679946649976335 14 P53985,P41440,P33527,P08183,Q96QD8,P30825,Q8WWI5 7 +Positive regulation of lipid metabolic process 0.5639630591835577 1.845032045551063 0.0650328771695014 1.0 0.2694142631185711 20 Q9NRA0,Q92604,Q12770,Q8WTV0,P16435 5 +Organic hydroxy compound transport 0.4772656613151136 1.8442758671035708 0.0651429466695923 1.0 0.2694142631185711 34 P61916,P22466,Q96SU4,O14656,O15118,Q9BXW6,Q86Y82,P30536,Q8WTV0,Q14849,Q14728 11 +Peptidyl glutamic acid modification 0.8459773744799655 1.8439536073860492 0.0651899015369923 1.0 0.2694142631185711 5 Q8N0U8 1 +Regulation of water loss via skin 0.8740815076318065 1.8439235290029907 0.0651942855331304 1.0 0.2694142631185711 4 P04062 1 +Cell maturation 0.4968760157024023 1.8429880758508783 0.0653307514859471 1.0 0.2694142631185711 31 Q8N2A8,Q9NZJ7,P04062,Q8IXJ6 4 +Regulation of metal ion transport 0.454150986560688 1.8428020930472695 0.0653579111170543 1.0 0.2694142631185711 59 P22466,Q12959,Q9UMX0,P21796,Q9NRA0,P46934,O76024,P27105,P30536 9 +Sodium ion transport 0.5026660605574274 1.8406108003284647 0.0656786138855232 1.0 0.2698093675358993 30 P05023,Q4KMQ2,Q12959,P46934,Q9Y6M7,Q6P4Q7,P27105,Q96QD8,Q92581 9 +Chloride transport 0.6117145167345315 1.8390877943310775 0.0659022739769077 1.0 0.2705611556547322 15 Q4KMQ2,Q9C0H2,P08183,Q96S66,P30536,Q9UHG3 6 +Protein quality control for misfolded or incompletely synthesized proteins 0.6497574233376235 1.8374525198262603 0.0661431196311141 1.0 0.2713825284494851 12 Q16740,Q9BUN8,P46379,O14656 4 +Mitochondrial fusion 0.6012649921942652 1.8365875132005376 0.0662708120784587 1.0 0.271680219251083 16 Q8N2A8,Q9Y3D6,Q99536,O95140,Q8TB36,Q9Y6C9,Q9NX63,O60313 8 +Homophilic cell adhesion via plasma membrane adhesion molecules 0.6893743558785403 1.8337352662119464 0.0666933009751864 1.0 0.2717966429821591 9 P35613,Q14574,Q9Y639,O15031 4 +Glycolipid transport 0.8656548622821829 1.8295918552269572 0.0673109925537795 1.0 0.2735998557539785 3 Q9NZJ7,P07602 2 +Regulation of hormone levels 0.4380336097125041 1.8278204954100377 0.067576496208167 1.0 0.2738540635661477 70 Q6NUM9,P22466,P42892,O95563,O75844,Q53GQ0,Q8N5M9,Q12846,O95470,Q9HB40,P30536,Q9UBM7,P40939,Q14849,P16435 15 +Leukotriene biosynthetic process 0.8648116919617785 1.826208351565432 0.067818883833294 1.0 0.2742557986180267 3 P09960,Q99735 2 +Protein targeting to lysosome 0.6472682228610963 1.8243398770025816 0.0681007053146236 1.0 0.274672844768982 12 Q14108,P46934 2 +Proton transporting two sector atpase complex assembly 0.8408323959504911 1.823142197763324 0.0682818568868821 1.0 0.2752366793350701 5 Q8N511,Q9BUB7,Q92544,Q15070 4 +Phosphatidylcholine metabolic process 0.6183154381113424 1.8221782449520432 0.068427944413353 1.0 0.2752884865289645 14 Q8NF37,Q8NCC3,Q8WTV0 3 +Phosphatidylinositol metabolic process 0.5061038848013305 1.8219658197468436 0.0684601720819588 1.0 0.2752884865289645 29 Q9BTU6,Q10713,Q92604,O43292,O14735,Q9H490,Q96N66,Q92643,Q5H8A4 9 +Homologous chromosome segregation 0.6598704335366383 1.8184594315034033 0.0689939418645833 1.0 0.2760872488559202 11 Q92791,Q9BTX1,P46379 3 +Protein o linked glycosylation via threonine 0.8623390197952512 1.8162810663374984 0.0693272681153516 1.0 0.276602499584931 3 Q10472 1 +Regulation of glycoprotein metabolic process 0.6722885862522143 1.813752244927006 0.069715877682472 1.0 0.2779863187398749 10 Q99805,Q9Y287 2 +Positive regulation of anion transmembrane transport 0.8648309734855895 1.8073459199288096 0.0707083604158556 1.0 0.2796082079663255 4 P08183 1 +Mast cell activation 0.762534836032454 1.8038478709192929 0.0712551589322116 1.0 0.2810925208618072 7 Q9NRA0 1 +Mast cell activation involved in immune response 0.762534836032454 1.8038478709192929 0.0712551589322116 1.0 0.2810925208618072 7 Q9NRA0 1 +Phosphatidic acid metabolic process 0.8129553547998613 1.7996198098822052 0.0719206909103236 1.0 0.282484378043527 6 Q8NF37,Q9HCL2,Q9NPH0 3 +Regulation of amino acid transmembrane transport 0.8580252468879852 1.798944965636893 0.072027386737647 1.0 0.282484378043527 3 Q15041 1 +L glutamate import across plasma membrane 0.8580252468879852 1.798944965636893 0.072027386737647 1.0 0.282484378043527 3 Q15041 1 +Regulation of l glutamate import across plasma membrane 0.8580252468879852 1.798944965636893 0.072027386737647 1.0 0.282484378043527 3 Q15041 1 +Keratan sulfate metabolic process 0.8580172799141514 1.7989129281408025 0.0720324552276281 1.0 0.282484378043527 3 P16278 1 +Regulation of potassium ion transmembrane transporter activity 0.628296002558349 1.7979040018395704 0.0721922218619322 1.0 0.2828732589120882 13 P22466,P46934 2 +Negative regulation of smooth muscle cell proliferation 0.7105556513154316 1.7962833654882515 0.0724494620411517 1.0 0.283618335225803 8 P09601,P04179,P09493 3 +Cell death in response to oxidative stress 0.5134808381074738 1.7948246260935574 0.0726816459300079 1.0 0.2836928760493857 27 O75915,Q9UMX0,P04062,Q07820,P23246,Q9UL15,P04179,Q99720 8 +Positive regulation of myotube differentiation 0.7549873559988776 1.7941716536273813 0.0727857750703706 1.0 0.2838932672466849 2 Q16539 1 +Import across plasma membrane 0.5427715008220053 1.7935869703610388 0.0728791177512253 1.0 0.2838932672466849 22 O75915,P05023,P41440,Q15758,Q15041,Q12959,P55011,P08195,Q8TDW0,Q9BXP2,P30825,Q92581 12 +Purinergic nucleotide receptor signaling pathway 0.8566508093722449 1.7934168755851256 0.0729062911868121 1.0 0.2838932672466849 3 P00813 1 +G protein coupled receptor signaling pathway 0.4559921518328754 1.7931666620494906 0.0729462790370896 1.0 0.2838932672466849 51 Q9NZJ7,P22466,P07602,P42892,Q9NRA0,Q99720 6 +Regulation of anion transmembrane transport 0.7599319968528901 1.792417681132206 0.0730660846239454 1.0 0.284027332460489 7 P08183,Q15041 2 +Negative regulation of toll like receptor signaling pathway 0.8608624433300767 1.7916218530120074 0.0731935601656019 1.0 0.2842004758098127 4 Q9NPR9 1 +Amelogenesis 0.7541444225906043 1.7902852023650615 0.0734080739049565 1.0 0.2842004758098127 2 Q6P4Q7 1 +Enamel mineralization 0.7541444225906043 1.7902852023650615 0.0734080739049565 1.0 0.2842004758098127 2 Q6P4Q7 1 +Vacuolar localization 0.5614827877481363 1.7895887697721382 0.0735200451943418 1.0 0.2844627330048517 19 Q9NRA0 1 +Positive regulation of mitochondrion organization 0.5266702993924044 1.7833168562406991 0.0745347390116033 1.0 0.2871610143082516 24 Q8N2A8,Q96A26,P21796,P27544,P12235 5 +Negative regulation of amyloid beta clearance 0.8541315345699857 1.7832785525651644 0.0745409708984699 1.0 0.2871610143082516 3 Q16850,P04035 2 +Regulation of autophagy 0.3831959939724847 1.7825846392250029 0.0746539421342709 1.0 0.2871803380945508 108 P09601,Q9NZJ7,P10619,P07602,Q9UMX0,O75844,P21796,P04062,Q93050,P46934,O15118,P27544,Q86UE4,P30536,Q8IXJ6 15 +Water homeostasis 0.707551894661581 1.7822146585888867 0.0747142332690904 1.0 0.2872462290039265 8 P04062,Q16739 2 +Regulation of neurotransmitter uptake 0.8303678582648235 1.7807014983116602 0.0749612282592471 1.0 0.2876847219052312 5 P41440,O75955 2 +Positive regulation of ion transport 0.4590545922752324 1.779054877754796 0.0752307653555179 1.0 0.2883990457609287 44 P22466,Q15041,P30536,Q9NRA0,O76024,P08183 6 +Regulation of dna ligation 0.7516156223658288 1.7786199978570527 0.0753020832481978 1.0 0.2885062544713626 2 P09429 1 +Membrane protein intracellular domain proteolysis 0.8518830803822388 1.7742240197483483 0.0760261026152475 1.0 0.2909452058105075 3 Q92542,Q8TCT8 2 +Cellular response to unfolded protein 0.4878056620106727 1.7710651108445092 0.0765498749551036 1.0 0.2926131061609506 31 Q6NTF9,P57088,P48723,Q9Y4P3,Q7Z2K6,O76024,Q96HY6,Q15363,Q9BUN8 9 +Fatty acid metabolic process 0.3833328085682456 1.770264307200594 0.0766831210461136 1.0 0.2929412873594192 106 Q9UKU0,P23786,O15254,Q8NCG7,A1L0T0,Q8NCC3,Q53GQ0,Q16134,P07099,Q9NZ01,O15121,Q12770,Q8N4Q0,O95864,Q9P035,Q9HCL2,Q9H7Z7,Q92604,Q6Y1H2,O00767,Q9BWD1,P51648,Q13510,P16435,P49748,O43808,Q15800,Q13011,P40939,O95470 30 +Pigment metabolic process 0.4993001526092592 1.769868566560571 0.0767490382925235 1.0 0.2929412873594192 29 P09601,P30536,O00264,P30519,P22830,Q9P0S9 6 +Nucleoside triphosphate biosynthetic process 0.460868639616014 1.7647504991659366 0.0776057073304432 1.0 0.2957995316632874 35 Q13232,P56385,P56134,Q9UIJ7,P36542,Q9NRA0,Q9UJZ1,O75947,O75964,P06576,Q9UJS0,P24539,P00403 13 +Protein import into peroxisome matrix 0.7479629109300272 1.761755001763186 0.0781107004877736 1.0 0.297043835283505 2 O75381 1 +Regulation of membrane lipid distribution 0.7523134537083656 1.758893797097258 0.0785955489507388 1.0 0.297920002923482 7 Q4KMQ2,P08183,Q96CP7 3 +Regulation of ion transmembrane transport 0.439662066003486 1.7566688681220275 0.0789742669052198 1.0 0.2986214467353624 64 O75915,P22466,Q15041,Q12959,Q9UMX0,P0CG08,O75844,P21796,Q9NRA0,P46934,Q99623,P27105,P08183 13 +Long chain fatty acyl coa metabolic process 0.6477559711178782 1.7561153653338213 0.0790687120162096 1.0 0.2986392045788169 11 Q8WVX9,Q53GQ0,Q6Y1H2,Q9NZ01,Q9UKU0 5 +Modified amino acid transport 0.8019059263337328 1.7538756148948875 0.0794518228093243 1.0 0.2995761364283591 6 O43772,Q96QD8 2 +Snare complex assembly 0.7459960663107494 1.7526665202363747 0.0796592657252681 1.0 0.2996791483333293 2 Q12846 1 +Regulation of electron transfer activity 0.8458299671317221 1.7498201471718355 0.0801493530515018 1.0 0.300106508768185 3 Q9NRA0 1 +Magnesium ion transport 0.8503087020097573 1.7497150431310633 0.0801674966183427 1.0 0.300106508768185 4 Q8IUH4,Q8N4V1 2 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.8008244701479031 1.7493889273602932 0.0802238135384825 1.0 0.300106508768185 6 Q9P0I2,Q5J8M3,Q8N4V1,Q9NPA0 4 +Regulation of glucocorticoid metabolic process 0.8454947364062535 1.7484674491058378 0.0803831173264146 1.0 0.3005335088804998 3 P22466 1 +Blood vessel endothelial cell migration 0.5165650838030988 1.7445037213555687 0.0810712930739487 1.0 0.300704826968562 25 Q8WTV0,P42785 2 +Myeloid cell activation involved in immune response 0.6447412815150575 1.7405421895670523 0.0817638586294327 1.0 0.300704826968562 11 P09601,Q9NRA0 2 +Regulation of hormone metabolic process 0.7982315625752756 1.738624824886095 0.082100776949944 1.0 0.300704826968562 6 O75844,P22466,P16435 3 +Positive regulation of leukocyte degranulation 0.8187629695909697 1.7334660776832465 0.0830128617924617 1.0 0.3030256601144495 5 Q12846,Q9NRA0 2 +Phosphatidylinositol biosynthetic process 0.5046183021776327 1.7290160000384875 0.0838062315194141 1.0 0.3044380298917582 27 Q9BTU6,Q10713,O43292,O14735,Q9H490,Q96N66,Q92643,Q5H8A4 8 +Walking behavior 0.8405461029889867 1.7284850516441137 0.0839012987480525 1.0 0.3046170993825911 3 O75844 1 +Mitochondrial proton transporting atp synthase complex assembly 0.840359752670041 1.727732067535135 0.0840362715405917 1.0 0.3049178205488352 3 Q9BUB7,Q15070 2 +Glutamate receptor signaling pathway 0.817097801557663 1.7266741193898516 0.0842262061925633 1.0 0.3051948593661527 5 Q92542,P0DMN0,Q8NCG7 3 +Regulation of anion transport 0.6148211788188065 1.7243509820514884 0.0846445008736478 1.0 0.3058760489017934 13 Q7L0J3,P08183,Q15041 3 +Atp synthesis coupled proton transport 0.6415932552329436 1.7242556029188791 0.0846617103045985 1.0 0.3058760489017934 11 P56385,P36542,Q9UJZ1,O75947,O75964,P06576,P24539 7 +Regulation of cellular respiration 0.6005557862877587 1.72242976616614 0.0849916954278509 1.0 0.3065689610148226 14 P14406 1 +Signal peptide processing 0.8149606299212382 1.7179518152268365 0.0858054045408587 1.0 0.3090016056382114 5 Q8TCT9,O75503,Q15005,P67812 4 +Eosinophil mediated immunity 0.7375667322281414 1.7136597534654394 0.0865912325010023 1.0 0.3106427081698895 2 Q12846 1 +Eosinophil activation 0.7375667322281414 1.7136597534654394 0.0865912325010023 1.0 0.3106427081698895 2 Q12846 1 +Negative regulation of cell growth 0.4544386424062713 1.711484551271179 0.0869917006526894 1.0 0.3112827106076725 37 P36896,Q9P0J0,Q9NRA0,Q9NQC3,P50897 5 +Positive regulation of pattern recognition receptor signaling pathway 0.6640365807512488 1.7098656462579866 0.087290720363262 1.0 0.3113181907918053 9 P41440,O75955,Q9NQC3 3 +Detection of stimulus 0.5595167167936141 1.7090042063211657 0.0874501703256251 1.0 0.3117198090610796 18 Q13432,Q8WTV0 2 +Mitochondrial cytochrome c oxidase assembly 0.7907172995780665 1.7073770276144926 0.0877519973862259 1.0 0.312460964475834 6 O75880,Q9Y2R0,Q96I36,Q15070,O43819 5 +Respiratory chain complex iv assembly 0.7907172995780665 1.7073770276144926 0.0877519973862259 1.0 0.312460964475834 6 O75880,Q9Y2R0,Q96I36,Q15070,O43819 5 +Glial cell proliferation 0.8120189475509089 1.705936797909511 0.0880198475679874 1.0 0.3130796822901958 5 P30536,P04062 2 +Regulation of mitophagy 0.6910996835017666 1.7048327413649071 0.0882256232352403 1.0 0.3131421454029462 8 P12235,P27544,P21796 3 +Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization 0.7353189098061181 1.7032430879752285 0.0885225862251752 1.0 0.3136942552335152 2 O95140 1 +Amyloid precursor protein catabolic process 0.5763368912576251 1.68948835629914 0.0911258813646633 1.0 0.3179423092129255 16 O95197,Q15392 2 +Regulation of leukocyte proliferation 0.5041866284512622 1.6891091527528004 0.0911985141668061 1.0 0.3179423092129255 26 P30825,P22466,P00813,Q12959 4 +Negative regulation of ire1 mediated unfolded protein response 0.7319471761730717 1.6876068271816012 0.0914867278145419 1.0 0.318599776873771 2 Q96HY6 1 +Positive regulation of protein exit from endoplasmic reticulum 0.8068985852988151 1.684997846476887 0.0919889869909273 1.0 0.3200139615392691 5 P51572,Q92544,Q9NR31 3 +Regulation of retrograde protein transport er to cytosol 0.8292750316641382 1.6828779103342155 0.0923987286444592 1.0 0.3204436583063091 3 P51572 1 +Neurotransmitter transport 0.4707506623096884 1.6821251478830324 0.092544574853093 1.0 0.3204436583063091 32 P41440,Q9P253,O75955,P16615,O14656,Q7L0J3,P50897,Q12846,Q5SQN1,Q96QD8 10 +Neutral amino acid transport 0.7845288326301058 1.6815841974770485 0.0926494970090408 1.0 0.3204436583063091 6 Q9H9B4,Q9H2J7,P08195,Q96NB2,Q96QD8 5 +Amine transport 0.6582740452677616 1.681492671939396 0.0926672586464123 1.0 0.3204436583063091 9 O75915,Q7L0J3,Q15041 3 +Activation of protein kinase c activity 0.7302613093565491 1.6797837434945382 0.0929993992185633 1.0 0.3208455167441883 2 Q99623 1 +Activation of phospholipase c activity 0.7302613093565491 1.6797837434945382 0.0929993992185633 1.0 0.3208455167441883 2 Q99623 1 +Regulation of phospholipase c activity 0.7302613093565491 1.6797837434945382 0.0929993992185633 1.0 0.3208455167441883 2 Q99623 1 +Regulation of aerobic respiration 0.6327672786818215 1.678461505636757 0.0932570392316924 1.0 0.321401137279603 11 P14406 1 +Positive regulation of anion transport 0.6853522768732649 1.6776741941954956 0.0934107198807914 1.0 0.3217641515562457 8 P08183 1 +Positive regulation of synaptic vesicle endocytosis 0.7296993537510441 1.677175328489955 0.0935082019722257 1.0 0.321933307876442 2 O14656 1 +Calcium import into the mitochondrion 0.7337179986642439 1.6766579132810264 0.0936093949793701 1.0 0.3219485910013996 7 Q96AQ8,P21796 2 +Chloride transmembrane transport 0.6842975617681656 1.6726833995617094 0.0943896389207825 1.0 0.3237953850607257 8 Q4KMQ2,P51798,Q9BXP2,P51790,Q9UHG3 5 +Pyramidal neuron differentiation 0.8297941418852608 1.6678972319082148 0.0953361292793157 1.0 0.3250887806559447 4 O14949 1 +Neutrophil differentiation 0.8297702141956727 1.6678015396676875 0.0953551301551596 1.0 0.3250887806559447 4 Q14739,Q8N5M9 2 +Mucopolysaccharide metabolic process 0.6552642449829519 1.6666447048582764 0.0955850740213193 1.0 0.3252140427463599 9 Q8NCH0,Q8N6G5,P16278 3 +Reactive oxygen species metabolic process 0.4453210721179135 1.6658652020155185 0.095740265894491 1.0 0.3254093307088038 46 Q13423,Q9NRA0,Q8IXJ6,Q9BSK2,P00374,P30536,P42785,P00403 8 +Mitochondrial genome maintenance 0.654439977177577 1.6625750358792444 0.096397531681571 1.0 0.3255741301009573 9 Q9BSK2,O60313 2 +Olefinic compound metabolic process 0.5414428990798971 1.6611081434382762 0.0966917292453091 1.0 0.3255741301009573 19 Q6NUM9,O95864,Q8N2K0,Q8NCG7,Q9Y394,Q9H7Z7,P07099,Q14849 8 +Regulation of protein secretion 0.4453655172709888 1.6600418176526128 0.0969060402538053 1.0 0.3255741301009573 45 Q5T9L3,O95563,Q8N5M9,P53367,Q12846,Q16850,Q9H4A6,Q96KC8,P40939,P04035 10 +Establishment of protein localization to organelle 0.3545144320799779 1.656712192005944 0.0975776768864191 1.0 0.3269785698283582 195 Q9Y5J9,Q9Y3D6,Q9UGP8,Q14108,Q8WWC4,O60830,Q9NS69,Q99595,Q99797,Q10713,Q15005,Q9Y5M8,P13473,O43615,Q9Y512,Q9UNL2,Q53H12,P61026,P61009,Q15629,P56589,P46379,Q96RL7,P11279,O14925,P49257,Q8N4H5,O43681,O95140,O96008,P55786,Q8TB36,Q7Z3B4,P40855,O75381,P46934,P51572,Q15070,Q9P0J0,Q9Y5J6,P52789,Q99623,P02545,P30536 44 +Cardiolipin metabolic process 0.799565385812539 1.6549552317780232 0.0979335793384805 1.0 0.3271586272782899 5 Q96BW9,Q99623,P40939 3 +Lipid catabolic process 0.4047610632775059 1.6547796547621976 0.097969202402915 1.0 0.3271586272782899 80 Q9H6V9,P23786,Q8WTV0,O15254,Q8NCG7,A1L0T0,Q8NCC3,Q16134,P50897,P04062,Q9BWD1,Q13510,Q8N2A8,P49748,O43808,Q99735,Q13011,P17900,P40939,O95470,Q8IXJ6 21 +Apoptotic mitochondrial changes 0.4609952831544257 1.6518771874235243 0.0985595894197097 1.0 0.327471567495058 33 P05141,Q96A26,Q9H3K2,P52789,P45880,O60313,P02545,P12235 8 +Regulation of release of cytochrome c from mitochondria 0.6394980018201978 1.6485982216857085 0.0992299733016375 1.0 0.3280553762157961 10 P02545,Q96A26,Q9H3K2 3 +Positive regulation of cell migration by vascular endothelial growth factor signaling pathway 0.7229558864849689 1.6458471151167555 0.0997952393070871 1.0 0.3291066985077625 2 P04792 1 +Attachment of gpi anchor to protein 0.7971320725766488 1.644972616844918 0.0999754582040908 1.0 0.3295377287509779 5 Q92643,O43292 2 +Protein retention in golgi apparatus 0.8193603570477037 1.6426563418045446 0.1004540564904412 1.0 0.3309513593781616 3 Q9H4A6 1 +Icosanoid metabolic process 0.5385196270030274 1.6422309527734988 0.1005421502952337 1.0 0.3309692673586569 19 Q8NCG7,O14880,P09960,Q9H7Z7,Q99735,P07099,Q8N4Q0 7 +Xenobiotic transport 0.7962321674057404 1.641279065503945 0.1007394996573367 1.0 0.3309692673586569 5 P41440,P08183,P35670 3 +Diacylglycerol metabolic process 0.818999437886456 1.6411904540860058 0.1007578866519367 1.0 0.3309692673586569 3 Q9HCL2,Q8NCC3 2 +Glucocorticoid metabolic process 0.7959456245430065 1.6401027927927356 0.1009837958470183 1.0 0.3311395611743345 5 P22466 1 +Regulation of er to golgi vesicle mediated transport 0.7251991435273462 1.6387982582919436 0.1012552820460899 1.0 0.3317842944444748 7 Q9Y6B6,Q9P2W9,Q9NR31 3 +Response to food 0.7735481947544132 1.6356931370017256 0.1019038265593594 1.0 0.3330464126573127 6 Q6KCM7,P80303,Q9UMX5 3 +Negative regulation of steroid metabolic process 0.8214893002859092 1.634649731816725 0.1021224959097297 1.0 0.3333130016082646 4 P05023,Q12770 2 +Cellular response to oxygen levels 0.4448987548113499 1.6338592336525537 0.1022884113342983 1.0 0.3334740910465026 40 P09601,Q8N511,Q96A26,Q9UMX0,Q9Y4P3,P55786,P02545,Q8IXJ6 8 +Protein localization to extracellular region 0.4211077422194146 1.6331511856524323 0.1024372035690757 1.0 0.3334740910465026 69 P22466,P27824,Q5T9L3,O95563,Q86YV9,Q8N5M9,Q9UBV2,P53367,P49755,Q8N183,Q16850,Q8TBQ9,Q12846,Q9H4A6,Q96KC8,P40939,P04035,Q96PC5 18 +Transepithelial chloride transport 0.7201461084574277 1.632779401296187 0.1025154008464519 1.0 0.3334740910465026 2 P51798 1 +Sodium ion import across plasma membrane 0.7201461084574206 1.6327794012961545 0.1025154008464588 1.0 0.3334740910465026 2 Q92581 1 +Establishment of protein localization to endoplasmic reticulum 0.5052952249828323 1.63120971576088 0.1028460759327507 1.0 0.3341995289709258 24 Q9UGP8,Q15005,Q9Y5M8,O43681,Q9UNL2,P61026,P46379,Q15629 8 +Ether metabolic process 0.6478580312405844 1.630026407240297 0.1030959159389917 1.0 0.3345261095739321 9 P07099,O00116,Q6IAN0 3 +Pyrimidine containing compound transmembrane transport 0.8157608437019326 1.628031564882686 0.103518192944692 1.0 0.3349760932319074 3 Q9BSK2 1 +Cellular homeostasis 0.3591603015185134 1.6277239625849516 0.1035834297203994 1.0 0.3349760932319074 157 Q9Y3D6,Q16891,Q8WWC4,P0CG08,P13473,Q93050,Q9UJZ1,P35670,Q07820,O76024,Q12846,Q8N511,Q96TC7,Q92544,O75503,Q8N183,Q96AQ8,Q96ER9,P50897,O95202,Q96A33,Q92581,O75880,P09601,Q4KMQ2,P16615,O00255,O95563,P51572,Q9Y6M7,P10253,O43819,Q9UM00,P05023,P06576,Q9HC07,P09429,Q8N5M9,Q9NQC3,P52789,Q7L0J3,Q9Y639,P51790,O60826,P14735,Q9HD20,P05067 47 +Peptidyl proline hydroxylation 0.6746114613202755 1.6267521984035602 0.1037897376775647 1.0 0.3349760932319074 8 P07237,Q96HE7,Q13162,Q32P28,Q8N543,P13674 6 +Response to zinc ion 0.7922761433037577 1.6250312578944206 0.1041558986757158 1.0 0.3358321248482989 5 P09960 1 +Negative regulation of growth 0.4440997122095184 1.624120145847498 0.1043501691686716 1.0 0.3362955815096901 39 P36896,Q9P0J0,Q9NRA0,Q9NQC3,P50897 5 +L glutamate transmembrane transport 0.7217874584777424 1.6236046210830657 0.1044602185831227 1.0 0.3364872965492166 7 O75915,Q9UJS0,O75746,Q15041 4 +Lipoprotein localization 0.7918586060456405 1.6233153743259296 0.1045220046340422 1.0 0.336523435336019 5 Q13432,A6NIH7,O15260 3 +Detection of external biotic stimulus 0.8144792859861324 1.6228218548943962 0.1046274924052119 1.0 0.3367001750274108 3 Q8WTV0 1 +Regulation of endothelial cell chemotaxis 0.717898286035404 1.6223194569611348 0.1047349647330748 1.0 0.3367203817867697 2 P04792 1 +Positive regulation of endothelial cell chemotaxis 0.717898286035404 1.6223194569611348 0.1047349647330748 1.0 0.3367203817867697 2 P04792 1 +Reactive oxygen species biosynthetic process 0.6218860276177478 1.6217422852448409 0.1048585407416393 1.0 0.3367360415136359 11 Q9BSK2,Q9NRA0,P51790,P00403 4 +Negative regulation of transport 0.3868499619786427 1.6213201958403325 0.1049489859312928 1.0 0.3367360415136359 88 O75915,Q9GZP9,P09601,Q9UMX0,Q13432,P30533,P21796,Q8N5M9,P46934,Q08722,P53367,Q8N183,Q16850,P05067,P40939,P00813,P04035 17 +Negative regulation of mitochondrion organization 0.5738745895734183 1.620540690858375 0.1051161808010934 1.0 0.3367360415136359 15 Q9H3K2,Q99536,P02545,P30536,O60313 5 +Macromolecule depalmitoylation 0.7909340276969411 1.619515106976418 0.1053364787387489 1.0 0.3368641355148363 5 Q9NUJ1,Q9UMR5,P50897 3 +Regulation of toll like receptor 3 signaling pathway 0.8175428732077505 1.6188270345722329 0.1054844836225932 1.0 0.3371379364170885 4 P41440,O75955,Q9UMX0 3 +C21 steroid hormone metabolic process 0.8169707520967208 1.6165319640748077 0.10597934830722 1.0 0.3371379364170885 4 Q14849 1 +Amino acid import across plasma membrane 0.7688955806658024 1.6162020942090598 0.1060506261628306 1.0 0.3372034959931381 6 O75915,P30825,Q15041,P08195 4 +Maternal process involved in female pregnancy 0.6444432100213431 1.6131041414720104 0.1067218842605859 1.0 0.3383678607690326 9 Q9BQE5,P35613 2 +Membrane biogenesis 0.4889603285709552 1.6116983153700244 0.1070276044592857 1.0 0.3391755750840697 27 Q86XL3,O75955,Q16739,Q96CP7,Q8IXJ6 5 +Protein o linked glycosylation via serine 0.766706622645565 1.607022698306536 0.1080493889725202 1.0 0.3418988334628556 6 Q10472 1 +Acute inflammatory response 0.7876666787636162 1.606077977527058 0.108256777945066 1.0 0.3422559891802444 5 Q9BQE5 1 +Toll like receptor 4 signaling pathway 0.8097881829243445 1.6037398839989316 0.1087714005432494 1.0 0.3427538178173696 3 O75955 1 +Regulation of toll like receptor 4 signaling pathway 0.8097881829243445 1.6037398839989316 0.1087714005432494 1.0 0.3427538178173696 3 O75955 1 +Sulfate transport 0.809724564362004 1.6034809763056763 0.1088285058498397 1.0 0.3427538178173696 3 Q9UBX3,Q02978 2 +Regulation of necrotic cell death 0.5927708011747368 1.6028785622415838 0.10896146753534 1.0 0.3428551141596634 13 Q13510,P30536,P00403 3 +Ribonucleoside triphosphate biosynthetic process 0.4774052759791551 1.6003657701467873 0.1095174640800955 1.0 0.3441164888824532 29 Q13232,P56385,P56134,P36542,Q9NRA0,Q9UJZ1,O75947,O75964,P06576,Q9UJS0,P24539,P00403 12 +Antigen processing and presentation of exogenous peptide antigen via mhc class ii 0.7131216633885932 1.6000757554517393 0.1095817787017137 1.0 0.3441560817649385 2 Q99538 1 +Glial cell migration 0.5919322136205122 1.598232841235032 0.1099911673904234 1.0 0.3450375968658427 13 P30536,Q96N66,Q9NQC3 3 +Nucleoside triphosphate metabolic process 0.4357686466256363 1.5913938522795763 0.1115209670064318 1.0 0.3486172855813669 49 P56385,Q13232,Q9UIJ7,Q9H773,Q9NRA0,O60313,O75947,O75964,P24539,Q9UJS0,P00813,P00403 12 +Nuclear pore organization 0.5906492559126373 1.591121767088113 0.1115821747166052 1.0 0.3486172855813669 13 Q9BTX1 1 +Insulin processing 0.7108738409665576 1.589600781092514 0.11192482090311 1.0 0.3486172855813669 2 Q969M3 1 +Negative regulation of alcohol biosynthetic process 0.8063035701463108 1.5895537367507602 0.1119354322226766 1.0 0.3486172855813669 3 Q12770 1 +Negative regulation of cholesterol metabolic process 0.8063035701463108 1.5895537367507602 0.1119354322226766 1.0 0.3486172855813669 3 Q12770 1 +Neutral lipid metabolic process 0.5499865213214569 1.5879530120069825 0.1122969647217979 1.0 0.3492225701979277 17 Q8N2K0,Q9HCL2,Q8NCG7,Q9NUQ2,Q8NCC3,Q92604,Q96N66,Q8WTV0,Q9UBV2 9 +Regulation of generation of precursor metabolites and energy 0.4404126885013764 1.5871356235253162 0.1124819312146294 1.0 0.3493748569569042 35 P14406,Q9H3K2,Q9NRA0,Q9BSK2,Q99623,P14735 6 +Respiratory chain complex iii assembly 0.7613100073533678 1.5843672819526198 0.1131101628884114 1.0 0.3500535013887118 6 Q69YU5 1 +Early endosome to golgi transport 0.7129109424010065 1.583992779974532 0.1131953621320072 1.0 0.3500535013887118 7 P49257,O60499,O15260 3 +Glycosaminoglycan catabolic process 0.7602881473609613 1.5800735468112483 0.1140900245282297 1.0 0.3517562727074765 6 P04066,P08236,P54802,P16278 4 +Aminoglycan catabolic process 0.7602881473609613 1.5800735468112483 0.1140900245282297 1.0 0.3517562727074765 6 P04066,P08236,P54802,P16278 4 +Positive regulation of toll like receptor signaling pathway 0.7811981013220326 1.579442281230412 0.1142346457124965 1.0 0.35185108122662 5 P41440,O75955,Q9NQC3 3 +Response to manganese ion 0.7808884683588385 1.5781662196782646 0.1145274285071995 1.0 0.3520782070863121 5 P05067,P30536 2 +Maintenance of protein localization in organelle 0.5574720197180588 1.576775366331486 0.1148472216865248 1.0 0.3523781744231548 16 P24390,O94901,Q9UH99,O15258,O43292,P30536 6 +Response to estrogen 0.5662537753487981 1.5759813359081514 0.1150301045962483 1.0 0.352776657183425 15 P09601,P22466 2 +Multicellular organism aging 0.6004321443344731 1.574494189389082 0.115373243816365 1.0 0.3536660237668859 12 P04062 1 +Positive regulation of necrotic cell death 0.7586396056120146 1.5731440072473653 0.1156854769913953 1.0 0.3538723975536386 6 P30536 1 +Adult locomotory behavior 0.5651583595423931 1.5695622121761938 0.1165169954564004 1.0 0.3548872690711445 15 O75844,O15118,P50897,P51790,P05067 5 +Synaptic vesicle membrane organization 0.6625200171762691 1.5691765111779503 0.1166068157568869 1.0 0.3548872690711445 8 Q5SQN1,O43760,Q12846 3 +Regulation of transporter activity 0.4331827839116994 1.5668411577071069 0.1171518244059641 1.0 0.3556576563148252 49 P22466,Q12959,Q9UMX0,Q9NRA0,P46934,P27105,P08183 7 +Ribonucleoside metabolic process 0.6619887119530182 1.5666407647510576 0.117198683741309 1.0 0.3556576563148252 8 Q13126,O60725 2 +Purine ribonucleoside metabolic process 0.6619887119530182 1.5666407647510576 0.117198683741309 1.0 0.3556576563148252 8 Q13126,O60725 2 +Mitophagy 0.5464113512901208 1.5659271922586626 0.1173656630593025 1.0 0.3559609875015835 17 P05141,P21796,O95140,P27544,Q99623,P12235 6 +Low density lipoprotein particle clearance 0.623231069169823 1.565756579224943 0.1174056149610782 1.0 0.3559609875015835 10 Q8WTV0 1 +Melanocyte differentiation 0.7052542849114823 1.5633940755178592 0.1179599327979876 1.0 0.3571534816972738 2 Q86YV9 1 +Phenol containing compound catabolic process 0.7997155069874816 1.5627071071269374 0.1181215019733021 1.0 0.3571658460422195 3 P21964 1 +Response to topologically incorrect protein 0.4262777471594283 1.5577256824734724 0.119298289694423 1.0 0.3593687017839242 58 Q9GZP9,Q6NTF9,P57088,P48723,O95140,O14656,P50454,O76024,Q96HY6,Q9Y4P3,Q7Z2K6,Q9NXW2,P46379,Q15629,Q15363,Q8TCJ2,Q9BUN8 17 +Regulation of adherens junction organization 0.7038493958977164 1.5568383205865477 0.1195088765043559 1.0 0.3597157725628623 2 P35241 1 +Negative regulation of blood pressure 0.7743411948952288 1.5511611737025874 0.1208630641320389 1.0 0.3622772719691077 5 P42785 1 +Regulation of histamine secretion by mast cell 0.7021635290812023 1.5489693749333566 0.1213890822159999 1.0 0.3634027629993162 2 P51809 1 +Regulation of calcium ion transport 0.4420096027723962 1.5448181138979202 0.1223902645857364 1.0 0.3655422167811006 34 P30536,P21796,Q9NRA0,Q9UMX0 4 +Positive regulation of protein dephosphorylation 0.5686968503787178 1.5411179244795643 0.1232880881497429 1.0 0.3668815847520142 14 P04062 1 +Plasma membrane organization 0.4592093765991443 1.5409155015470368 0.1233373525457099 1.0 0.3668815847520142 31 Q4KMQ2,O75955,P16615,Q16739,Q96CP7,Q12846,Q9UQB8,O15121 8 +Muscle hypertrophy in response to stress 0.7969948840975858 1.5362171618711815 0.124485128264794 1.0 0.3691838362754923 4 P16615 1 +Iron ion homeostasis 0.5165283811842292 1.5340190033604153 0.1250249777690864 1.0 0.3702898206734624 20 Q8N511,P30519 2 +Mitochondrial calcium ion transmembrane transport 0.6167991201045315 1.532847203084876 0.1253135070937019 1.0 0.3708143128984376 10 Q96AQ8,Q8WWC4,P21796,O95202 4 +Fatty acid transmembrane transport 0.7010939765805411 1.5310858902406554 0.1257481665283446 1.0 0.3717199327186902 7 O43772,O14678,P23786 3 +Regulation of autophagy of mitochondrion 0.5498098940809085 1.5306736510749055 0.1258500689699848 1.0 0.3717199327186902 16 P12235,P27544,P21796,P30536 4 +Mitochondrial electron transport cytochrome c to oxygen 0.768385442403749 1.5265601825767767 0.1268704145154271 1.0 0.3726048581642399 5 P13073,P00403 2 +Hydrogen peroxide biosynthetic process 0.7902879756597527 1.5242347419768498 0.1274500822353976 1.0 0.3739772033847317 3 P00403 1 +Polyol metabolic process 0.489797817535916 1.519549843951803 0.1286241517418744 1.0 0.3765920500845466 24 Q13510,P04062,Q9NRA0,P00374 4 +Aminoglycan metabolic process 0.5472444525355744 1.5151981033392206 0.1297222432638884 1.0 0.3766069058380742 16 Q8NCH0,O43505,Q7LGA3,P04066,P16278,Q8N6G5,P54802,P08236 8 +Negative regulation of amyloid precursor protein catabolic process 0.651193611761107 1.5150179027330777 0.1297678704272795 1.0 0.3766069058380742 8 O95197 1 +Response to testosterone 0.5891317330973004 1.513384875738371 0.1301819244649176 1.0 0.3768424129247615 12 P30536,P04062 2 +Locomotory behavior 0.4608266327342246 1.510652527164376 0.130877003509666 1.0 0.3779267102181441 30 O75844,O15118,P50897,P51790,P10253,P05067,P04179,P54802,Q96RL7 9 +Programmed cell death 0.3162020149959633 1.5052339667909236 0.1322639352887249 1.0 0.3802231055492286 457 Q9BXK5,Q86XL3,Q9NZJ7,Q13232,P36896,Q9NS69,Q15041,Q9UMX0,P21796,Q9NRA0,Q9UHX1,Q9NVI7,P45880,Q07820,Q01105,Q96KA5,O76024,Q12846,P46379,Q8IWB1,Q9H4A6,Q99720,O95197,P24390,P22466,P11279,P50897,Q9UDX5,Q15392,Q14728,Q66K74,P09601,Q9HCL2,Q96A26,P04062,Q13510,P16435,P00813,P51812,O95881,O75844,Q9P0J0,O14681,Q9NQC3,P12236,Q9Y6C9,P02545,Q86UE4,P30536,O95470,Q8IXJ6 51 +Detection of biotic stimulus 0.7629672217032331 1.5041516103862544 0.132542334004214 1.0 0.3808589088074456 5 P30536,Q8WTV0 2 +Very long chain fatty acid metabolic process 0.574714927469795 1.5024533904733604 0.1329800566435346 1.0 0.3817870047293886 13 Q9P035,O14678,Q6Y1H2,Q9NZ01,Q9UKU0 5 +Positive regulation of monooxygenase activity 0.7619837037771875 1.5000812657328333 0.1335933531360584 1.0 0.3825493470234875 5 Q8WTV0,P00374 2 +Amyloid beta formation 0.5985559970128761 1.4992195695297148 0.1338166798478119 1.0 0.3825493470234875 11 Q92542,O95197,Q9NQC3 3 +L serine transport 0.7838673412029263 1.4979999127578152 0.1341332731241347 1.0 0.3825493470234875 3 Q9H9B4,Q96QD8 2 +Maintenance of protein location 0.4426890901769459 1.4976322310300116 0.1342288279194237 1.0 0.3825493470234875 33 P24390,O94901,P30536,P52789,O43292,Q9UH99,O15258,Q9H4A6,Q96RL7 9 +Establishment of protein localization to vacuole 0.5162631511086426 1.4974343278230002 0.1342802816899875 1.0 0.3825493470234875 19 P13473,Q14108,P46934 3 +Phosphate ion transmembrane transport 0.7824932162258851 1.4923820427597725 0.1355990198606378 1.0 0.3835152899160836 3 Q9UBX3 1 +Phosphate ion transport 0.7824932162258851 1.4923820427597725 0.1355990198606378 1.0 0.3835152899160836 3 Q9UBX3 1 +Cartilage development involved in endochondral bone morphogenesis 0.7843844290907585 1.4853532902699698 0.1374502621520565 1.0 0.3874339240245389 4 O75844,P16435 2 +Serine transport 0.7840877143660255 1.4841551797520902 0.1377677571858493 1.0 0.3878360507918051 4 Q96NB2,Q9H9B4,Q96QD8 3 +Negative regulation of neuron apoptotic process 0.4571852322541216 1.4814523927622951 0.1384860621471129 1.0 0.3895286321170906 30 P09601,Q01105,P50897,P04062 4 +Long chain fatty acid transport 0.5704132455455857 1.478410090039778 0.139298046320355 1.0 0.3914816293335991 13 O43772,O14678,P23786 3 +Molting cycle 0.5404671638127465 1.474222663752234 0.1404216496513159 1.0 0.3939734863314505 16 O75844,P22466 2 +Negative regulation of immune effector process 0.593668668067205 1.4734059973566196 0.1406415941030656 1.0 0.3942585546570774 11 Q08722,P09601 2 +Regulation of t cell apoptotic process 0.7540745968604721 1.4673201502085211 0.1422889847202697 1.0 0.396538188154688 5 P00813 1 +Inorganic ion import across plasma membrane 0.603861358726979 1.4664048984655311 0.1425380126384252 1.0 0.3968997799618075 10 P05023,P55011,Q12959,P23634,P54709,Q9BXP2,P05026,Q92581 8 +Aminoglycan biosynthetic process 0.6147304747937835 1.4649064589889669 0.1429464403618774 1.0 0.3976201040110887 9 Q8NCH0,Q8N6G5,O43505 3 +Cell adhesion molecule production 0.7791838561161634 1.464345750478062 0.1430995026623445 1.0 0.3977659324504071 4 Q9H4A6,O75955 2 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.7754356379988785 1.4635123801268313 0.1433272285523781 1.0 0.3977659324504071 3 P01889,P10321 2 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.7754356379988785 1.4635123801268313 0.1433272285523781 1.0 0.3977659324504071 3 Q9UIQ6,Q03518 2 +Ribonucleoside triphosphate metabolic process 0.4259284930164425 1.4608262811361643 0.1440631214910925 1.0 0.3990257309517833 39 Q13232,P56385,O75746,P56134,Q9UIJ7,P36542,Q9NRA0,Q9UJZ1,O60313,O75947,O75964,P24539,P06576,Q9UJS0,P00403 15 +Anterior posterior axis specification 0.59127788293269 1.46076127578753 0.1440809664127926 1.0 0.3990257309517833 11 Q8N2A8,Q5T9L3 2 +Antiviral innate immune response 0.7514190937389891 1.4563095827097008 0.1453070576701505 1.0 0.4019195630901295 5 Q9NVI7,Q9H078 2 +Dendrite self avoidance 0.7734264740662806 1.4552891834334976 0.1455892198611468 1.0 0.402365555720902 3 P35613 1 +Determination of adult lifespan 0.6839762556134444 1.4541265891483222 0.1459112130628816 1.0 0.4029207978977085 7 P04062 1 +Negative regulation of glial cell proliferation 0.7726829427479341 1.4522455554498788 0.1464333399698918 1.0 0.4033929616036911 3 P30536 1 +Amyloid beta metabolic process 0.5652888931296096 1.4497131174244828 0.1471385362597943 1.0 0.4041299871270868 13 Q92542,O95197,Q9NQC3,P14735 4 +Collagen biosynthetic process 0.7750839057062775 1.4477727226444228 0.1476806238109005 1.0 0.4047077097389948 4 Q92791,P08670 2 +Positive regulation of dephosphorylation 0.5444647298374476 1.4476633311870877 0.1477112298610157 1.0 0.4047077097389948 15 P04062 1 +Protein depalmitoylation 0.7747184162935845 1.4462948625086902 0.1480945161190492 1.0 0.4051700491194919 4 Q9NUJ1,P50897 2 +Skin epidermis development 0.535644711457752 1.4449867904242637 0.1484615960670887 1.0 0.4055878168417388 16 O75844,P22466 2 +Phagosome lysosome fusion 0.7706208294229575 1.44380307209058 0.148794377609315 1.0 0.405800163355091 3 Q9BZG1 1 +Negative regulation of vascular associated smooth muscle cell proliferation 0.7279947003186285 1.4438027615932043 0.1487944649748322 1.0 0.405800163355091 6 P09601,P09493 2 +Response to oxygen levels 0.4045557877632427 1.4421270737502898 0.1492665286632628 1.0 0.4061196844865144 68 Q8N511,P09601,Q92544,Q96A26,Q9UMX0,P52789,Q9Y4P3,P55786,P30519,Q99623,P02545,Q12770,P00813,Q8IXJ6 14 +Regulation of dna templated transcription in response to stress 0.5350640735702821 1.4414623825410329 0.1494540973737084 1.0 0.4061318979265126 16 P09601,Q8IXJ6,P51812 3 +Regulation of potassium ion transport 0.52602892768684 1.439575318093254 0.1499875867867315 1.0 0.4070829486401706 17 P22466,Q12959,P46934 3 +Tetrapyrrole biosynthetic process 0.5627611494207218 1.4355359187603636 0.1511344405045074 1.0 0.4091943456295756 13 P30536,O00264,P22830 3 +Lipid translocation 0.7257657230230123 1.4343600900754043 0.1514695305413693 1.0 0.4097681812003305 6 Q4KMQ2,P08183 2 +Plasma lipoprotein particle clearance 0.5849094181682837 1.4270256922403457 0.1535724891887495 1.0 0.4125360709643972 11 Q8WTV0 1 +Positive regulation of potassium ion transport 0.5958498145490334 1.42510784761304 0.1541260285340224 1.0 0.4132589524149554 10 P22466,Q12959 2 +Vascular associated smooth muscle cell proliferation 0.5843898756737572 1.4242702128371785 0.1543682667094637 1.0 0.4135158525905961 11 P09601,P04179,P09493 3 +Negative regulation of lipid biosynthetic process 0.6063737479158985 1.4229445096352695 0.1547522419524478 1.0 0.414211309397387 9 Q8NF37,P49748,P05023,Q12770 4 +Endoplasmic reticulum tubular network organization 0.5835734366262669 1.4199391086022215 0.155625409026191 1.0 0.4159385932005226 11 O95197,Q15041,Q9NQC3 3 +Toll like receptor 3 signaling pathway 0.7426035058541604 1.419721471237526 0.1556887846836694 1.0 0.4159409321837897 5 P41440,O75955,Q9UMX0 3 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.7680382242843837 1.41927114456433 0.1558199812928731 1.0 0.4159574711207663 4 P42892,P09493 2 +Positive regulation of skeletal muscle tissue development 0.7676076610715618 1.417528609647016 0.1563284358529346 1.0 0.416646271766632 4 O75955 1 +Positive regulation of muscle tissue development 0.7676076610715618 1.417528609647016 0.1563284358529346 1.0 0.416646271766632 4 O75955 1 +Regulation of cell killing 0.6043622882619627 1.412827870101158 0.1577063414896167 1.0 0.4192050997372964 9 P01889,P11279,O15400,Q9BY67 4 +Membrane raft organization 0.5933538913418221 1.4122197773432938 0.1578852589025308 1.0 0.4192050997372964 10 O15118,O75955,Q12959,P50897 4 +Protein insertion into mitochondrial inner membrane 0.7396400749677048 1.407410675384431 0.1593056474746705 1.0 0.4217100572569342 5 Q9P0J0,Q9Y5J6,Q53H12 3 +Intermembrane lipid transfer 0.6727829112717099 1.4036221257043064 0.16043140293473 1.0 0.4230075223972378 7 Q14849 1 +Regulation of sodium ion transport 0.5017619265603931 1.4021344516697118 0.1608751009205271 1.0 0.4239828076729162 19 P27105,Q12959,P46934 3 +Regulation of receptor mediated endocytosis 0.4566149930860507 1.3998084318016644 0.1615706922022017 1.0 0.4248811371671783 28 P41440,O75955,Q9UL25,Q13432,P50897,P05067 6 +Regulation of lymphocyte apoptotic process 0.6271706055328025 1.3995056910455812 0.1616613929457542 1.0 0.4248811371671783 8 Q96GD4,Q9HCL2,P00813 3 +Pyrimidine nucleoside triphosphate metabolic process 0.5562274650812241 1.3988276589447364 0.1618646699509898 1.0 0.4248811371671783 13 Q9H773,Q9UIJ7 2 +Striated muscle adaptation 0.7361250744461536 1.3928017868388154 0.1636797379436654 1.0 0.427869415592285 5 P16615 1 +Sterol transport 0.4722492604904919 1.391817005039567 0.1639778191790433 1.0 0.4279499555437385 24 P61916,Q96SU4,O15118,Q86Y82,P30536,Q8WTV0,Q14849 7 +Pinocytosis 0.6249236181271065 1.388661703199077 0.1649356448066985 1.0 0.4297304547258222 8 P50897,Q9H223 2 +Metanephric glomerulus development 0.6678842371452629 1.388614406367329 0.164950034239947 1.0 0.4297304547258222 2 P11047 1 +Nephric duct morphogenesis 0.667884237145263 1.388614406367329 0.164950034239947 1.0 0.4297304547258222 2 Q15375 1 +Nephric duct development 0.667884237145263 1.388614406367329 0.164950034239947 1.0 0.4297304547258222 2 Q15375 1 +Negative regulation of leukocyte apoptotic process 0.7145204859970296 1.3866615479697535 0.1655449909458748 1.0 0.4301842697168282 6 Q96GD4,Q9HCL2,P00813 3 +Negative regulation of lymphocyte apoptotic process 0.7145204859970296 1.3866615479697535 0.1655449909458748 1.0 0.4301842697168282 6 Q96GD4,Q9HCL2,P00813 3 +Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis 0.6670413037370011 1.384666156969849 0.166154572011778 1.0 0.4311547424920794 2 Q13177 1 +Neutral lipid biosynthetic process 0.6239552232739295 1.3839863514857655 0.1663626339427328 1.0 0.4312985309267188 8 Q92604,Q8NCC3,Q8WTV0 3 +Negative regulation of leukocyte proliferation 0.62389230860275 1.3836825649662456 0.1664556744502745 1.0 0.4313716952751468 8 P22466 1 +Response to sterol depletion 0.7136612938017185 1.3830133236275273 0.1666607805977009 1.0 0.4315319070406089 6 Q15363,Q12770 2 +Cellular response to sterol depletion 0.7136612938017185 1.3830133236275273 0.1666607805977009 1.0 0.4315319070406089 6 Q15363,Q12770 2 +Response to activity 0.5076319567647603 1.3799751323167448 0.1675943016358736 1.0 0.4334784599248888 18 Q15388,Q6KCM7,Q9UDX5,P04179,O43819,P40939 6 +Regulation of cellular response to vascular endothelial growth factor stimulus 0.6653554369204804 1.376769461711844 0.1685835352563947 1.0 0.4348174060198586 2 O00159 1 +Ion homeostasis 0.3528237115122458 1.3754476613961348 0.1689927013979804 1.0 0.4352346856824921 121 Q9Y3D6,Q16891,Q8WWC4,P0CG08,Q93050,P35670,O76024,P30519,Q8N511,Q96TC7,Q92544,O75503,Q96AQ8,P50897,O95202,Q6P4Q7,Q96A33,Q92581,O75880,P09601,P16615,P51572,Q9Y6M7,O43819,Q9UM00,P05023,P06576,Q9HC07,P09429,Q7L0J3,Q9Y639,P04179,P51790,O60826,Q9HD20,P05067,P30536 37 +Regulation of dendritic cell differentiation 0.7535371901572251 1.3738030320534311 0.1695028395829352 1.0 0.4363796508411736 3 P01889 1 +C4 dicarboxylate transport 0.5857563629084268 1.3729275482892185 0.169774871437687 1.0 0.4369109703858495 10 Q15758,O75746,P55011,Q8TDW0,Q9UBX3,Q02978,Q9UJS0 7 +Hormone catabolic process 0.7531671914205417 1.3722861003783562 0.1699743909219817 1.0 0.4372553427080743 3 P42892 1 +Mitochondrial electron transport nadh to ubiquinone 0.4656945582384871 1.3718097320403164 0.1701226768398995 1.0 0.4374677026157386 25 O43676,O96000,Q9Y6M9,P03886,O95168,Q9Y375,P51970 7 +Taurine transport 0.6639505479067105 1.3701887464581286 0.1706279902818943 1.0 0.4380899981967619 2 Q8TDW0 1 +Intracellular protein transport 0.3278596549273873 1.367754160826001 0.1713890404595848 1.0 0.439437191908772 354 Q9GZP9,Q14108,O60830,Q9NS69,Q15041,Q99595,P10619,Q10713,O60499,Q15005,Q9Y5M8,P13473,Q969Q5,Q9NR31,O43615,O15260,Q9Y512,Q9UNL2,Q8TCT9,Q12846,P46379,Q15629,Q53H12,P56589,Q96RL7,Q5BJH7,P50402,Q9P253,Q9UL25,Q92544,O14925,Q8WWC4,P43307,Q8N4H5,Q9Y282,O43681,P49257,O95140,O96008,P53367,P49755,P55786,Q8TB36,P53365,Q9Y6B6,Q86Y82,Q7Z3B4,P40855,Q9UEU0,Q5T9L3,O75381,O15400,P46934,P51572,Q9P2W9,Q15070,Q15363,O15504,O60725,Q9BUN8,Q9P0J0,Q9Y5J6,Q99623,P02545,Q5W0Z9,P27105,P30536,Q9Y3A6,Q9UBV2 69 +Regulation of transmembrane transport 0.3848875555380766 1.365277548814667 0.1721658326465764 1.0 0.4408478708206874 77 O75915,Q4KMQ2,P22466,Q15041,Q12959,Q9UMX0,P0CG08,O75844,P21796,Q9NRA0,P52789,P46934,Q99623,P27105,P08183 15 +Neuron apoptotic process 0.4078456084259343 1.3646914654831854 0.1723500431770148 1.0 0.441149822055013 57 P09601,Q96A26,P04062,Q07820,Q01105,P50897,Q99720 7 +Positive regulation of activated t cell proliferation 0.7502184711459645 1.3601960058577427 0.1737679061893957 1.0 0.4435083120468171 3 Q9HCL2 1 +Response to misfolded protein 0.583115030483838 1.359246821817309 0.1740683889034318 1.0 0.4435083120468171 10 Q9BUN8,P46379,O14656 3 +Terpenoid metabolic process 0.5044021370022375 1.35920480218173 0.1740817000033334 1.0 0.4435083120468171 18 Q9HB40,P37268,P51648,P48449 4 +T cell apoptotic process 0.5602739277788837 1.356091922352442 0.1750699226436898 1.0 0.4447292001830375 12 P24390,P00813 2 +Epidermis development 0.4093738674558653 1.355237764348189 0.1753418163712474 1.0 0.4447412479066371 53 P36896,P16615,Q16739,P22466,O75844,P51648,Q13510 7 +Regulation of endothelial cell migration 0.441450964894723 1.3544729476426929 0.1755855384011915 1.0 0.4451511459275922 30 Q8WTV0,P42785 2 +Cellular copper ion homeostasis 0.7065270870717706 1.352702135786029 0.1761508078601883 1.0 0.4459044903344489 6 O75880,P05067,O60826,P35670 4 +Regulation of atp biosynthetic process 0.7064778555683788 1.352492856651486 0.1762177024161684 1.0 0.4459044903344489 6 Q9NRA0 1 +Protein import into peroxisome membrane 0.7481731309724597 1.3518091274367976 0.176436383507625 1.0 0.4460346583540578 3 P56589,P40855 2 +Bone morphogenesis 0.6608902217433308 1.3498301920247249 0.1770704578544144 1.0 0.4468069277767023 7 O75844 1 +Er overload response 0.7249418810369496 1.346280261611394 0.1782121490073258 1.0 0.4478816501074909 5 Q96A33,Q9UM00 2 +Endoplasmic reticulum calcium ion homeostasis 0.57977899813285 1.3419536874062958 0.1796110124890308 1.0 0.4492371295437979 10 P16615,Q9UM00,P51572,O76024,P05067,Q96A33 6 +Regulation of plasma lipoprotein particle levels 0.545521501593389 1.3384942961575552 0.1807353584563529 1.0 0.451160469064902 13 Q8WTV0 1 +Developmental maturation 0.4088097872182744 1.336274180047785 0.1814596726622919 1.0 0.4521372933985088 50 Q8N2A8,Q9NZJ7,P22466,P04062,Q8IXJ6 5 +Positive regulation of autophagy of mitochondrion 0.6578892211343855 1.336237743592274 0.1814715780190685 1.0 0.4521372933985088 7 P12235,P27544,P21796 3 +Positive regulation of cell division 0.5255638262902613 1.3353689818068546 0.181755611557103 1.0 0.452349885905954 15 O14908,Q15058,Q9H0H5,Q7Z7K6,Q96GD4,P67809,P37198,Q8IXJ6 8 +Fat soluble vitamin metabolic process 0.6575614682318762 1.3347528410195606 0.1819572528476327 1.0 0.4524782924301356 7 Q8N0U8,P04062 2 +Regulation of heterotypic cell cell adhesion 0.7470597126430574 1.3342868786493725 0.1821098561724596 1.0 0.4524782924301356 4 P41440,O75955 2 +Negative regulation of macroautophagy 0.5556919065424246 1.330974393733633 0.1831974365954218 1.0 0.4544225710872382 12 P09601 1 +Phagosome maturation 0.7461873279021318 1.3307501006990992 0.1832712518103902 1.0 0.4544225710872382 4 Q9BZG1 1 +Phagolysosome assembly 0.7461873279021318 1.3307501006990992 0.1832712518103902 1.0 0.4544225710872382 4 Q9BZG1 1 +Nerve development 0.6124531910468612 1.3283754256445928 0.1840541135832376 1.0 0.4548385168572025 8 Q9H061 1 +Alditol phosphate metabolic process 0.744988351394986 1.3258890463977913 0.1848764517215604 1.0 0.4563214561007307 4 Q9NPH0 1 +Glycerol 3 phosphate metabolic process 0.7417088251826901 1.3252999336239997 0.1850716910076033 1.0 0.4565055980932543 3 Q8N335,Q9HCL2 2 +Phosphatidylcholine catabolic process 0.7413195358397484 1.3237034573122228 0.1856015497945171 1.0 0.4571348311926393 3 Q8WTV0 1 +Regulation of nuclear cell cycle dna replication 0.7410993186420527 1.3228003458539266 0.1859017821977735 1.0 0.4575787361308779 3 O75844 1 +Regulation of amino acid transport 0.6549122762834948 1.3227477025030978 0.1859192941394281 1.0 0.4575787361308779 7 Q7L0J3,Q15041 2 +Phosphatidylglycerol biosynthetic process 0.7408656548622854 1.3218420899012104 0.1862207393869854 1.0 0.4580930285617733 3 Q96BW9,Q9HCL2 2 +Regulation of neurotransmitter levels 0.4102228413794538 1.3196931582584674 0.1869374852403758 1.0 0.45923062280454 35 P41440,Q9P253,Q8NCG7,P21964,O75955,P16615,Q7L0J3,P50897,Q12846,Q5SQN1 10 +Positive regulation of cell adhesion molecule production 0.7396053525534033 1.3166735942774976 0.1879480584100781 1.0 0.4605219454105764 3 O75955 1 +Protein localization to membrane raft 0.7418421789379035 1.3131323419779706 0.189138357417113 1.0 0.4618105519368162 4 P41440,O75955 2 +Ammonium transmembrane transport 0.651587524585554 1.3122834293739265 0.1894245210853351 1.0 0.4619348434675358 2 P55011 1 +Folic acid metabolic process 0.6078011611890507 1.3058456041177071 0.1916050679816385 1.0 0.4649854909191969 8 P41440,Q9H2D1,P00374 3 +Unsaturated fatty acid metabolic process 0.4720180325634168 1.3045746833789549 0.1920377135495512 1.0 0.4650965530443928 22 O95864,Q9H7Z7,P07099,O00767,O15121,Q8N4Q0 6 +Bicarbonate transport 0.736649803260262 1.3045531032637656 0.1920450660280646 1.0 0.4650965530443928 3 Q9Y6M7,P04920 2 +Regulation of leukocyte mediated cytotoxicity 0.6075046154082349 1.3044087705399587 0.1920942464003627 1.0 0.4650965530443928 8 P01889,P11279,O15400,Q9BY67 4 +Antigen processing and presentation of exogenous peptide antigen 0.7137232845894229 1.2995615597641872 0.1937512817711626 1.0 0.4685373474517032 5 P04439,Q9UIQ6,Q99538,Q03518 4 +Cellular response to molecule of bacterial origin 0.4241177936378067 1.293942221586868 0.1956853790712254 1.0 0.4725276479386811 32 Q86UE4,P30536,Q8WTV0,Q8IXJ6 4 +Er associated misfolded protein catabolic process 0.6481907884358694 1.292267636511067 0.1962644756374758 1.0 0.4734106869762239 7 Q9BUN8,P46379 2 +Negative regulation of calcium ion transport 0.5700318503603099 1.291343235148504 0.1965846847892365 1.0 0.4739896457591398 10 P21796 1 +Mannosylation 0.6046373904414911 1.2905125625512193 0.1968727529084759 1.0 0.4739896457591398 8 Q9BT22,Q2TAA5,Q6ZXV5 3 +Cdp diacylglycerol metabolic process 0.6475688247359194 1.2894458315958273 0.1972431366410911 1.0 0.4742243765702535 7 Q96BW9,Q9HCL2,Q9NUQ2,O14735 4 +Entry into host 0.4122004782497694 1.2851862191926962 0.1987272181086801 1.0 0.476415575112848 34 Q9P253,Q14108,P35613,O15118,Q8WTV0 5 +Retina morphogenesis in camera type eye 0.7348889513634945 1.2849357995043946 0.1988147196154743 1.0 0.4764537122941958 4 Q16706,Q8NBN7,P54802 3 +Endochondral bone morphogenesis 0.709550465611545 1.2821757435886556 0.1997810032043379 1.0 0.4779326453943474 5 O75844 1 +Sterol homeostasis 0.5355553954516374 1.282147448150922 0.1997909270453906 1.0 0.4779326453943474 13 Q8WTV0,Q5BJF2 2 +Positive regulation of cell killing 0.6455613705129637 1.28033671949454 0.2004267389118719 1.0 0.4786607108022056 7 P01889,P11279,O15400,Q9BY67 4 +Regulation of complement activation 0.7304665542439609 1.279198631369689 0.200827117704383 1.0 0.4788302522806065 3 Q99623,Q07021 2 +Complement activation 0.7304665542439609 1.279198631369689 0.200827117704383 1.0 0.4788302522806065 3 Q99623,Q07021 2 +Regulation of humoral immune response 0.7304665542439609 1.279198631369689 0.200827117704383 1.0 0.4788302522806065 3 Q99623,Q07021 2 +Outer mitochondrial membrane organization 0.7086702318842292 1.2785078985448486 0.2010704015674467 1.0 0.4788302522806065 5 Q9NS69 1 +Potassium ion import across plasma membrane 0.6021230137857718 1.2783210143991424 0.2011362612047733 1.0 0.4788302522806065 8 P05023,P55011,Q12959,Q9BXP2,P05026 5 +Insulin secretion involved in cellular response to glucose stimulus 0.5777080954282817 1.2782538989987706 0.2011599171098024 1.0 0.4788302522806065 9 Q12846,O95563,Q8N5M9 3 +Regulation of insulin secretion involved in cellular response to glucose stimulus 0.5777080954282817 1.2782538989987706 0.2011599171098024 1.0 0.4788302522806065 9 Q12846,O95563,Q8N5M9 3 +Regulation of glial cell proliferation 0.7328006779563501 1.2764671499791462 0.2017904320393482 1.0 0.4792702802362107 4 P30536 1 +Leukocyte proliferation 0.4050522894216619 1.2721371843167806 0.203324381474889 1.0 0.4818816804541976 41 Q9HCL2,P22466,Q12959,P04062,P00813,P30825 6 +Lipid storage 0.4986361240352019 1.2679175367279245 0.2048274008004591 1.0 0.4837212038066201 17 Q9H6V9,P04062,Q8WTV0,Q14534 4 +Positive regulation of mononuclear cell migration 0.543471925756164 1.2638315382002758 0.2062904986903606 1.0 0.4857973350263093 12 Q08722,Q4KMQ2,P09429,P05067 4 +Glycolipid catabolic process 0.6416773555869706 1.2627066952450592 0.20669460700908 1.0 0.4860033553295156 7 P04062 1 +Neuron maturation 0.6853593711795742 1.262613421106323 0.2067281422321634 1.0 0.4860033553295156 6 Q9NZJ7,O75503 2 +Peripheral nervous system development 0.5206067467400778 1.262532166587973 0.2067573592121823 1.0 0.4860033553295156 14 Q9NR77,P51648 2 +Positive regulation of chemokine production 0.6415570905241249 1.262160685665318 0.2068909721253158 1.0 0.4860033553295156 7 P09601,P09429,P05067,Q7Z434 4 +Negative regulation of intrinsic apoptotic signaling pathway 0.42019498498908 1.2607390471999127 0.2074028807535759 1.0 0.4860033553295156 32 O95881,Q9P0J0,Q07820,O76024,P45880,O60313,P04179 7 +Second messenger mediated signaling 0.4299015033891933 1.2604967039708208 0.2074902361625814 1.0 0.4860033553295156 30 P22466,P16615,P0DMN0,O75844,Q96SB3,P00813 6 +Regulation of cytoplasmic translational initiation 0.7256885890950007 1.2596110335408506 0.2078097132945056 1.0 0.4863135299255429 3 P42345,P40429 2 +Regulation of cation transmembrane transport 0.400569947344473 1.2593230297648927 0.2079136782253114 1.0 0.4863499221755529 51 P22466,Q12959,Q9UMX0,P21796,Q9NRA0,P46934,P27105 7 +Regulation of nitric oxide metabolic process 0.5425825607805215 1.258936967546384 0.2080530999065173 1.0 0.4865050526626397 12 Q08722,P30536 2 +O glycan processing 0.6406285543819025 1.2579448739856651 0.2084116933630844 1.0 0.4868304034156991 7 Q10472,Q8N4A0,Q9H488,O43505 4 +Negative regulation of glycoprotein metabolic process 0.7240022484541914 1.2526991107758465 0.2103152297233679 1.0 0.4895585357848945 3 Q9NY61,Q9Y287 2 +Positive regulation of regulated secretory pathway 0.6823040525225943 1.2495972356357308 0.2114467134579398 1.0 0.491065896869064 6 Q12846,Q9NRA0 2 +Arachidonic acid secretion 0.6381005900533795 1.2491641848129624 0.2116050286079787 1.0 0.4911864197370416 2 P14174 1 +Endoplasmic reticulum to golgi vesicle mediated transport 0.3865151680292974 1.2468747190702048 0.2124434377873105 1.0 0.4923960713809568 68 Q5BJH7,P24390,Q9BVK6,Q9NZ43,Q9NR31,P49257,Q9Y282,P51572,P49755,O95070,Q9Y6B6,Q9P2W9,Q969X5,Q15363,Q8NHH9,Q12770,Q9Y3A6,Q96PC5 18 +Neuromuscular junction development 0.5402914629962604 1.2463236040411712 0.2126456155797871 1.0 0.4923960713809568 12 P49354,O15258,P46934 3 +Negative regulation of calcium ion transmembrane transport 0.5713677866383897 1.2461262138798013 0.212718062392224 1.0 0.4923960713809568 9 P21796 1 +Positive regulation of macroautophagy 0.4520379657794072 1.2432036365603452 0.2137928029871352 1.0 0.4934907256114564 24 P09601,P05141,P21796,P27544,P12235 5 +Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules 0.7214727374929772 1.2423328402661833 0.2141137834606263 1.0 0.4937377785621859 3 P19022,Q9BY67 2 +Pore complex assembly 0.528055972761274 1.2396472441474078 0.2151058981031721 1.0 0.4953390144901767 13 Q9BTX1 1 +Antigen processing and presentation of endogenous antigen 0.5700368861693831 1.2393779429153724 0.2152055659862035 1.0 0.4953971088336855 9 P01889,Q9NZ08,P10321,Q03518,P14735,Q03519 6 +Negative regulation of ion transmembrane transport 0.4854474476364824 1.236763607385035 0.2161748565456223 1.0 0.4964056623108608 18 P46934,P21796,Q9UMX0 3 +Negative regulation of receptor mediated endocytosis 0.5491360408095528 1.2363076032127571 0.2163442459884925 1.0 0.4964056623108608 11 Q13432,P05067 2 +Tubulin deacetylation 0.6787619509280285 1.2345050274336835 0.2170147745143671 1.0 0.4969832499632186 6 P49354 1 +Membrane docking 0.4169515154160244 1.2332315445445723 0.2174893895704786 1.0 0.4978988261408789 32 Q9P253,Q9UEU0,P16615,O60499,Q9H270,O15400,Q9UNK0,Q12846,P61026,Q86Y82 10 +Negative regulation of transmembrane transport 0.461284592449283 1.2287513303979565 0.2191650543413297 1.0 0.5001126724415915 22 P46934,P21796,Q9UMX0 3 +Vesicle tethering 0.6966586818505215 1.228450468256434 0.2192779123787192 1.0 0.5001126724415915 5 O95772 1 +Regulation of sodium ion transmembrane transport 0.49228718491632 1.2278829873634969 0.2194908967904103 1.0 0.5001126724415915 17 P27105,P46934 2 +Regulation of t cell mediated cytotoxicity 0.7206591060456302 1.227235866361729 0.2197339525498443 1.0 0.5001126724415915 4 P01889,O15400 2 +Positive regulation of t cell mediated cytotoxicity 0.7206591060456302 1.227235866361729 0.2197339525498443 1.0 0.5001126724415915 4 P01889,O15400 2 +Regulation of cholesterol metabolic process 0.567399211549862 1.2259997722057965 0.2201987607534994 1.0 0.5005866617117924 9 P49748,O76054,Q9UBM7,Q12770,P16435 5 +Negative regulation of b cell apoptotic process 0.7202758293046574 1.2256821582999162 0.2203183068600811 1.0 0.5005866617117924 4 Q96GD4,P00813 2 +Regulation of b cell apoptotic process 0.7202758293046574 1.2256821582999162 0.2203183068600811 1.0 0.5005866617117924 4 Q96GD4,P00813 2 +Regulation of morphogenesis of a branching structure 0.7195416973860138 1.2227062700118407 0.2214406579505694 1.0 0.5017662848692679 4 Q9NQC3 1 +Regulation of amyloid precursor protein catabolic process 0.5136840031308161 1.2220607039615017 0.2216846719237204 1.0 0.5017921921467638 14 O95197 1 +Dna catabolic process exonucleolytic 0.6322000561955556 1.2215825623848384 0.2218655261766628 1.0 0.5017921921467638 2 Q9GZR2 1 +Negative regulation of fat cell differentiation 0.6326003824940385 1.2214814894919055 0.2219037699351866 1.0 0.5017921921467638 7 Q8N4Q0 1 +Negative regulation of map kinase activity 0.5665077949851752 1.2214774243648954 0.2219053081885649 1.0 0.5017921921467638 9 P04062 1 +Autophagy of mitochondrion 0.399395998418638 1.220636442578163 0.222223701882245 1.0 0.5018319430018123 36 P05141,P21796,P04062,O95140,P52789,P27544,Q99623,P30536,P12235 9 +Regulation of response to osmotic stress 0.6752615189434937 1.2195887561643288 0.2226208109166347 1.0 0.5019684647919396 6 P08183 1 +Maintenance of location 0.3828014431043834 1.218634809320316 0.2229828310572053 1.0 0.5019684647919396 69 P24390,O94901,P30536,P04062,P52789,Q14534,P35670,Q9H6V9,O95202,O43292,P10253,Q9UH99,O15258,Q9H4A6,P17900,Q8WTV0,Q96RL7 17 +Maternal placenta development 0.6942964945403288 1.2186062863786595 0.2229936619160626 1.0 0.5019684647919396 5 Q15363,P35613 2 +Protein polyufmylation 0.7154704223920446 1.2177439750702763 0.2233212803728768 1.0 0.5019684647919396 3 Q96HY6 1 +Reticulophagy 0.7154704223920446 1.2177439750702763 0.2233212803728768 1.0 0.5019684647919396 3 Q96HY6 1 +Neurotransmitter secretion 0.4543101750166156 1.21763016541429 0.2233645458540567 1.0 0.5019684647919396 23 Q9P253,P16615,Q7L0J3,P50897,Q12846 5 +Intracellular lipid transport 0.5128922443062504 1.2174277163597078 0.2234415229990722 1.0 0.5019684647919396 14 P61916,O43772,O14678,O15118,P23786 5 +Mitotic nuclear membrane organization 0.6746308258774438 1.2169010976649672 0.2236418479501278 1.0 0.5019684647919396 6 Q8IXJ6 1 +Amyloid precursor protein biosynthetic process 0.7173284419266648 1.213735437057448 0.2248487675853059 1.0 0.5034887443742297 4 Q92542,Q9Y287 2 +Negative regulation of cytokine production 0.4146264568199841 1.213484036795374 0.224944813916383 1.0 0.503494313044499 32 P09601,P04062 2 +Maintenance of location in cell 0.3981470850581802 1.211000199431982 0.2258953282660902 1.0 0.503494313044499 43 P24390,O94901,P30536,P35670,O95202,O43292,P10253,Q9UH99,O15258,Q9H4A6,Q96RL7 11 +Interleukin 6 production 0.5047669120869432 1.2109607546066867 0.2259104460932943 1.0 0.503494313044499 15 P01889,P04062,Q9NRA0,Q08722,P05067 5 +Lipid homeostasis 0.4281016025826268 1.2093275429694543 0.2265370332950393 1.0 0.504284197726068 29 P61916,Q9HCL2,Q5BJF2,Q96CP7,O15260,Q9NQC3,O15118,Q9Y6C9,Q8WTV0,O15254,Q86YV9 11 +Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii 0.7133220910623983 1.2089470306046033 0.226683196060708 1.0 0.504284197726068 3 Q9NVJ2,Q99538 2 +Icosanoid biosynthetic process 0.5541720886138136 1.2087742971886646 0.2267495687757013 1.0 0.504284197726068 10 P09960,Q9H7Z7,Q8NCG7,Q99735 4 +Lysosomal transport 0.3950641742719127 1.2087694817499386 0.2267514193038138 1.0 0.504284197726068 52 Q9NZJ7,Q14108,Q9P253,P07602,P13473,P46934,O15118 7 +Regulation of cd40 signaling pathway 0.6293902781680196 1.2084582189283812 0.2268710575494887 1.0 0.504284197726068 2 O15360 1 +Regulatory t cell differentiation 0.6293902781680196 1.2084582189283812 0.2268710575494887 1.0 0.504284197726068 2 O15360 1 +Neuron projection regeneration 0.5438938984863863 1.2082264162213552 0.2269601834229671 1.0 0.504313863332169 11 P30536,Q96G23,P10586,P00374 4 +Regulation of exit from mitosis 0.629519385772004 1.2074829661424202 0.2272462011526326 1.0 0.5046124353255822 7 P50748,Q99623,Q8IXJ6 3 +Cellular lipid catabolic process 0.3848986026162518 1.2062054882664912 0.227738268301048 1.0 0.5051993918478249 66 P23786,Q8WTV0,O15254,Q8NCG7,A1L0T0,Q8NCC3,Q16134,P50897,P04062,Q9BWD1,Q13510,P49748,O43808,Q99735,Q13011,P17900,P40939,O95470,Q8IXJ6 19 +Neuron recognition 0.6291130101586647 1.2056364550470458 0.2279576964354777 1.0 0.5053492570879761 7 P05067,P35613,Q9NQC3 3 +Signaling receptor ligand precursor processing 0.7124207148350455 1.2052567780299528 0.2281041896065749 1.0 0.5053945349144447 3 P42892 1 +Small molecule metabolic process 0.316765569540696 1.203491988684257 0.228785989695097 1.0 0.5060415019427136 522 Q9BQE5,P09960,P21796,Q9NRA0,Q8N0U8,P49589,Q16850,O75964,Q06136,P37268,Q8WTV0,Q9H773,Q8NCC3,P07099,P50897,Q15392,O76062,Q14849,Q8N4Q0,Q9BRR6,P04062,P51648,Q13510,O60725,Q9HB40,Q8TB61,Q9H2D1,O75844,Q15800,Q9UBX3,Q14739,P40939,O95470,P38435,Q9HC21,O15118,Q9UKU0,P48449,Q9UMR5,Q53GQ0,P21912,O00116,P00374,O95864,Q9P035,Q9H7Z7,O14874,Q92604,P43490,Q6Y1H2,P16435,P00403,Q92520,Q9UIJ7,Q13126,Q14534,Q13011,P00813,Q13232,Q10713,Q9UKK9,Q8WVC6,P16278,Q9UBM7,P23786,Q6NUM9,Q12959,Q16134,Q9NZ01,O15121,Q12770,Q9HCL2,P0DMN0,O76054,O95563,Q6IAN0,Q9NUJ1,O00767,Q9BWD1,P24539,P49748,O43808,Q99735,O60313,Q969T7,Q8NI60,Q8NBZ7,P04035,O15254,Q8NCG7,A1L0T0,O14678,P56385,Q9Y394,O75947,Q9BV57,P10253,Q9UJS0,P61916,P41440,O14880,Q96SU4,P52789,Q9BXW6,P06576,P05067 106 +Insulin metabolic process 0.7110736368746524 1.1997426137893277 0.2302393175068635 1.0 0.5074604021496929 3 Q969M3,P14735 2 +Negative regulation by host of viral genome replication 0.6274234335487435 1.199275452257739 0.2304208569197658 1.0 0.5074604021496929 2 Q9P0L0 1 +Cerebellar purkinje cell layer development 0.6274337707699087 1.198005956371302 0.2309146981496339 1.0 0.5078444534652392 7 P04062,O14949 2 +Regulation of mitochondrial membrane permeability 0.4873265562475266 1.196550328558012 0.2314818708160932 1.0 0.508755564822028 17 P45880,P05141,P12235 3 +Positive regulation of erad pathway 0.7121355680603607 1.192693527892993 0.232989421293011 1.0 0.5110562289732987 4 P46379,Q9UMX0 2 +Skeletal system morphogenesis 0.460925181759268 1.190790873651364 0.2337356925383542 1.0 0.5122035658562278 21 O75844,O95470,P16435 3 +L aspartate transmembrane transport 0.7107112735451148 1.186923915995299 0.2352576328091753 1.0 0.5141673387011697 4 O75746,Q15758,Q9UJS0 3 +Response to dexamethasone 0.5496528144333475 1.1852085888557262 0.2359349849001382 1.0 0.5145432463506264 10 P04062 1 +Necrotic cell death 0.4690902226804956 1.1851178684031625 0.23597084716185 1.0 0.5145432463506264 19 Q13510,P30536,P00403 3 +Dna methylation 0.476530001505258 1.1788829752324197 0.2384447777998231 1.0 0.5175635995622383 18 Q8N2A8 1 +Cerebral cortex radially oriented cell migration 0.5815015113288982 1.178188568379546 0.2387214389311094 1.0 0.5178263285810082 8 Q96N66,Q9NQC3 2 +Telencephalon glial cell migration 0.5815015113288982 1.178188568379546 0.2387214389311094 1.0 0.5178263285810082 8 Q96N66,Q9NQC3 2 +Regulation of action potential 0.5578537482414696 1.1775488087252814 0.2389765282861837 1.0 0.5180214670583133 9 P04062,P16615 2 +Ensheathment of neurons 0.4240606532027423 1.176801440698682 0.2392747674583746 1.0 0.5180214670583133 29 Q92542,O15228,Q9NR77,Q15058,P49770,Q12959,O75746,P42345,Q9Y4W6,O15121,Q8IXJ6 11 +Circulatory system process 0.3655821736229276 1.1761993280925536 0.2395152329412992 1.0 0.5182903348654163 79 Q8N335,P33527,Q12959,P09493,P08183,P42785,P30825,P09601,P16615,Q9NZ08,Q6PI78,P10253,O95319,Q96QD8,Q9HB40,P53985,P05023,P41440,P42892,O75844,P20020,P04179,Q9UIQ6,P00813,Q8WWI5 25 +Srp dependent cotranslational protein targeting to membrane 0.5377686693725405 1.1753865713862208 0.2398400934668654 1.0 0.5186622838517132 11 Q9UNL2,Q15629 2 +Blastocyst formation 0.5056791519865133 1.175185372082587 0.239920561183426 1.0 0.5186622838517132 14 Q9Y3A4,Q9NQC3 2 +Organelle membrane fusion 0.3946271925910409 1.1748249666106974 0.2400647494401138 1.0 0.5187113336116744 38 Q9BSR8,Q9UEU0,P51809,Q12981,Q92599,O60499,Q9H270,Q9NVJ2,Q9UNK0,O15400,Q8IWA4,Q5SQN1,Q12846,Q9BZG1,Q86Y82,O75396,Q969M3,O95721 18 +Protein localization to microtubule end 0.6220848552964258 1.1743706901451787 0.2402465798772999 1.0 0.5189357316077349 2 Q15555 1 +Positive regulation of calcium mediated signaling 0.7037690279590588 1.1698605547731868 0.2420570899560448 1.0 0.5202452148973388 3 P00813 1 +Import into cell 0.4041056758219131 1.1660550147591024 0.2435922030835926 1.0 0.5218762125715031 33 O75915,P05023,P41440,O75955,Q15041,Q12959,P30825,Q92581 8 +Regulation of nitric oxide synthase activity 0.6203449169157699 1.1657912806980195 0.2436988433854239 1.0 0.5218762125715031 7 Q8WTV0 1 +Positive regulation of monocyte chemotaxis 0.7052318946759777 1.1647362016481304 0.2441257903678635 1.0 0.5224620460750159 4 Q4KMQ2,P09429 2 +Exocytic process 0.4521469556858291 1.1639561878575964 0.2444417673044552 1.0 0.5224620460750159 22 Q9P253,Q9UEU0,Q9H270,Q7L0J3,Q5SQN1,Q12846,P61026,O95721 8 +Gland development 0.3644082344813201 1.162258428260219 0.2451305075251062 1.0 0.5226989835243775 79 P09601,Q9NZJ7,P00403,P07602,Q5T9L3,O75844,Q9NQC3,P35670,P30536,Q13505 10 +Cellular response to nutrient 0.5779468190508433 1.160911570570539 0.2456778629372045 1.0 0.5230100552238193 8 P09601 1 +Positive regulation of synaptic vesicle recycling 0.7015177065767324 1.160657987661477 0.2457810134100511 1.0 0.5230100552238193 3 Q96CW1,O14656 2 +Protein mannosylation 0.7040806619645549 1.160076415331368 0.246017695531399 1.0 0.5230100552238193 4 Q6ZXV5 1 +Protein o linked mannosylation 0.7040806619645549 1.160076415331368 0.246017695531399 1.0 0.5230100552238193 4 Q6ZXV5 1 +Transepithelial transport 0.6611273058985928 1.1593598677025938 0.246309528113866 1.0 0.5232013755498816 6 P33527,P51798,P08183,P78310 4 +Regulation of amyloid beta clearance 0.6796965098455858 1.157785596582762 0.2469515426580679 1.0 0.5240633024201028 5 Q16850,P04035 2 +Response to immobilization stress 0.6603645682883515 1.1561104247886238 0.2476359924827433 1.0 0.5250627956564013 6 Q96SB3,P22466 2 +Adenylate cyclase inhibiting g protein coupled receptor signaling pathway 0.5534082136578906 1.1549694475968355 0.2481029380784503 1.0 0.5255474879284201 9 P07602 1 +Regulation of intrinsic apoptotic signaling pathway 0.3900105397616114 1.154916188655624 0.2481247493720655 1.0 0.5255474879284201 51 P07237,Q9Y3D6,Q9UMX0,O95881,Q9P0J0,Q9NYF8,Q07820,O76024,P45880,P51572,P23246,Q9UL15,O60313,Q9Y4L1,P04179 15 +Negative regulation of leukocyte mediated immunity 0.6178802643834165 1.1545908923747836 0.2482579980550974 1.0 0.5256624171354354 7 P09601 1 +Mammary gland development 0.4555009385968684 1.1530709826187888 0.2488812507236744 1.0 0.5261450837249216 21 Q9NQC3,P35670,Q99623,Q13505,P00403 5 +Negative regulation of release of cytochrome c from mitochondria 0.6781204957560297 1.1512242230013896 0.249640002337022 1.0 0.5269780239205724 5 P02545,Q9H3K2 2 +Phosphatidylcholine biosynthetic process 0.5757107676602076 1.150042697100491 0.2501262859429234 1.0 0.5272696968483229 8 Q8NF37,Q6IAN0,Q8WWI5 3 +Double strand break repair via break induced replication 0.5521559595186669 1.148607982840208 0.2507176638755557 1.0 0.5275731585896857 9 Q9BRT9,Q9Y248 2 +Cobalamin transport 0.6982500348980549 1.1473078933600005 0.2512543928842989 1.0 0.5276421535642188 3 O14678 1 +Peripheral nervous system axon regeneration 0.700698130182806 1.1463894875256255 0.2516340304705906 1.0 0.5279396194141805 4 P30536 1 +Kinetochore assembly 0.7006004673027395 1.1459944112439515 0.2517974645167249 1.0 0.5281016796931409 4 P50748 1 +Regulation of dna primase activity 0.7001715014347594 1.1442591841076382 0.2525161649254315 1.0 0.5288807638091622 4 Q9Y248 1 +Chemokine production 0.5508113739675254 1.1417770534234448 0.2535467027794271 1.0 0.5299476466699395 9 P09601,P09429,P05067,Q7Z434 4 +Cell cell adhesion via plasma membrane adhesion molecules 0.4856434969013642 1.1386870052214255 0.254833724643102 1.0 0.531802583098101 16 P19022,P35613,P10586,Q9Y639,Q14574,Q9BY67,O15031,Q16539 8 +Heparan sulfate proteoglycan biosynthetic process 0.6749565255581078 1.1380551349950505 0.2550974605739724 1.0 0.5318101598850994 5 Q99805 1 +Trophoblast cell migration 0.6959393676786084 1.1378729907460616 0.255173520877535 1.0 0.5318101598850994 3 P36896 1 +Nervous system process 0.3361825102228278 1.137428169706577 0.2553593367538709 1.0 0.5318101598850994 113 Q92542,O43924,Q14108,Q13432,O76024,P04035,O75915,Q9Y6M9,P50897,Q6P4Q7,Q9UQB8,Q96SB3,P04062,O00264,P10253,O60313,O75844,P17900,O14773,P05067 20 +Peptidyl asparagine modification 0.5492185235010969 1.1336844027873247 0.2569269544547721 1.0 0.5343277755926589 9 P61803,P46977,P04843,Q9H0U3,Q8TCJ2 5 +Fatty acyl coa biosynthetic process 0.5090358745646922 1.1315727337950052 0.2578141087052112 1.0 0.5355033999479341 13 Q9UMR5,Q53GQ0,Q6Y1H2,P50897,Q9UKU0 5 +Clathrin dependent endocytosis 0.460741388892369 1.1292670241303808 0.2587852072451648 1.0 0.5365157489771253 19 Q13432,Q5VW38 2 +Potassium ion homeostasis 0.6523206751054943 1.121852048067942 0.2619253519130369 1.0 0.5420128162255163 6 P05023,P55011,P54709,Q9BXP2,P05026 5 +Sodium ion export across plasma membrane 0.6919617762788125 1.1216430197276837 0.2620142525871234 1.0 0.5420282408975151 3 P05023,P05026 2 +Negative regulation of endocytosis 0.49617837957216 1.119468208753555 0.2629404461895914 1.0 0.5431851404166143 14 Q13432,P05067 2 +Positive regulation of i kappab kinase nf kappab signaling 0.3885289876023307 1.1186890603949948 0.2632728138056897 1.0 0.5431851404166143 38 P09601,O43657,Q8TB61,Q5T9L3,Q8IUH4 5 +Regulation of nucleotide biosynthetic process 0.5691235593592986 1.1180234448694213 0.2635569803565611 1.0 0.5431934667924789 8 Q9NRA0 1 +Positive regulation of long term synaptic potentiation 0.6931660309968002 1.115938932274347 0.2644482754301795 1.0 0.5446265946348745 4 P05067,Q9Y639 2 +Isoprenoid metabolic process 0.4280945057528061 1.1158231455700185 0.2644978443065235 1.0 0.5446265946348745 26 Q6NUM9,Q9Y394,P51648,P37268,P04035,Q9HB40,P48449 7 +Negative regulation of peptide secretion 0.6089666204362073 1.1140916030257262 0.2652398906055206 1.0 0.5456480593445874 7 P40939,Q8N5M9 2 +Negative regulation of hormone secretion 0.6089666204362073 1.1140916030257262 0.2652398906055206 1.0 0.5456480593445874 7 P40939,Q8N5M9 2 +Regulation of monooxygenase activity 0.5358242210759344 1.113040425724445 0.2656910677656259 1.0 0.5462385097251283 10 Q8WTV0,P00374 2 +Cellular potassium ion homeostasis 0.6921563114984385 1.1118600777893255 0.2661983159574805 1.0 0.54704506570508 4 P05023,P05026,P55011 3 +Signal release 0.3796458293945376 1.1117450624767693 0.266247778785688 1.0 0.54704506570508 62 Q9P253,P22466,P16615,Q5T9L3,O95563,Q8N5M9,Q7L0J3,P50897,Q12846,Q5SQN1,P40939 11 +Transition metal ion transport 0.4875535211482504 1.1075225090422671 0.2680680859787805 1.0 0.5480751776419716 15 Q9HD20,Q9HC07,Q8N4V1,O15173 4 +Regulation of exocytosis 0.3868733438657223 1.105940696239813 0.2687521886854545 1.0 0.5488020299790425 44 P09601,Q9P253,P11279,P16615,Q9NRA0,Q12846 6 +Divalent inorganic cation homeostasis 0.3816575669282922 1.1037108898776185 0.2697185702051328 1.0 0.5496874107703802 58 Q9Y3D6,Q16891,Q8WWC4,P35670,O76024,Q96TC7,Q96AQ8,O95202,Q6P4Q7,Q96A33,P16615,P51572,Q9UM00,Q9HC07,P09429,Q7L0J3,Q9Y639,Q9HD20,P05067 19 +Vesicle mediated transport 0.2949444578665154 1.1021931135782443 0.2703777251913608 1.0 0.5504255075577783 413 Q8NBN3,Q14108,Q9UL25,Q9NR31,Q13432,O60499,P30533,O15260,Q9NRA0,O15126,O15118,Q12846,Q8TBQ9,Q9H4A6,P55899,Q8WTV0,Q96RL7,Q5BJH7,O95197,P24390,Q9P253,P11279,P27824,Q92544,Q9NZ43,Q9Y282,O75503,O95772,Q08722,P53367,P50897,O43760,Q9UBC2,Q86Y82,Q8NHH9,Q15057,Q12770,Q14849,Q9NX40,P09601,Q4KMQ2,O75955,P16615,Q9BRK5,O15127,O15400,Q5VW38,P46934,P51572,Q9P2W9,Q8TBA6,Q969X5,Q15363,Q9H0R1,P41440,Q9H223,Q12981,Q8N5M9,O14656,Q7L0J3,O95070,Q9Y3E0,Q9BXW6,Q5SQN1,P51790,O15258,O60826,P05067,Q9Y3A6,Q96PC5 70 +Negative regulation of ion transport 0.4481953432919805 1.1021788711557567 0.2703839157583276 1.0 0.5504255075577783 21 P46934,P21796,Q9UMX0 3 +Membrane protein proteolysis 0.5237710812385382 1.1002661892834773 0.2712161590425843 1.0 0.5511277979934042 11 Q92542,Q8TCT8,Q9NZ08,Q8TCT9,Q16740 5 +Regulation of proton transport 0.565259252632053 1.0992420406388237 0.2716625057655197 1.0 0.5518662930004682 8 Q9NRA0 1 +Long chain fatty acid metabolic process 0.4290732999391349 1.0969622326930533 0.2726579021405979 1.0 0.552370879374636 25 O95864,Q8NCG7,P28288,Q9H7Z7,P07099,P23786,Q9UKU0 7 +Positive regulation of response to endoplasmic reticulum stress 0.5644226170102602 1.0951762666596887 0.2734394211837934 1.0 0.5534487068060052 8 P57088,P46379,Q9UMX0 3 +Aspartate transmembrane transport 0.6645106861642139 1.0946176065296844 0.2736841988444274 1.0 0.5537483094343816 5 Q9H936,Q8TDW0,Q9UJS0,O75746 4 +Icosanoid transport 0.6850993025613472 1.0936793097924995 0.2740956517139756 1.0 0.5538953299515982 3 P33527 1 +Selective autophagy 0.40030733875487 1.0913924218006588 0.2751002455517894 1.0 0.5547300253132309 32 P05141,Q9UMX0,P21796,O95140,Q96HY6,P27544,Q99623,O15269,P12235 9 +Response to axon injury 0.4779604831819918 1.0912654513977775 0.275156095200447 1.0 0.5547300253132309 16 P10586,P04179,Q96G23,P00374,P30536 5 +Lipid modification 0.3815447667090299 1.0910157629438766 0.2752659466167571 1.0 0.5547834266306839 56 P49748,Q10713,O43808,Q9NTJ5,P28288,A1L0T0,O14678,Q9NRA0,Q16134,P04062,P40939,Q13011,Q9BWD1,Q96N66,P23786,P16435,O15254 17 +I kappab kinase nf kappab signaling 0.3814436660398723 1.0899813723025726 0.2757213496766542 1.0 0.5555330251583813 56 P09601,O43657,Q9P035,Q8TB61,Q5T9L3,Q9NRA0,Q8IUH4 7 +Plasma membrane raft assembly 0.6836924688085897 1.0879531153020272 0.2766158058740751 1.0 0.5560145207373086 3 O75955 1 +Plasma membrane raft organization 0.6836924688085897 1.0879531153020272 0.2766158058740751 1.0 0.5560145207373086 3 O75955 1 +Regulation of muscle organ development 0.5623824596646417 1.085262687191533 0.2778053268277851 1.0 0.556865798204491 8 O75955,Q8IXJ6 2 +Negative regulation of blood circulation 0.6828293529260541 1.0844411669993097 0.2781692392780088 1.0 0.5572773201773213 3 P16615 1 +Vitamin metabolic process 0.3945688048280045 1.083010176663325 0.2788039060055196 1.0 0.5578592887753256 33 Q9HC21,Q9H2D1,P04062,Q8N0U8,P38435 5 +Organic hydroxy compound catabolic process 0.4831846225685711 1.081229389909529 0.2795950876650028 1.0 0.5584349665097821 15 Q8WTV0,P21964,Q10713 3 +Establishment of protein localization 0.3206454761499955 1.0809943250525655 0.2796996380059224 1.0 0.5584761748963138 583 Q9P0I2,Q9GZP9,Q14108,O60830,Q9NS69,Q8WWC4,Q99595,Q13432,Q8N4V1,O15126,Q12893,Q8TCT9,Q53H12,Q16850,Q03518,Q15629,P56589,Q8TEM1,Q86YV9,Q8N766,P24390,P22466,P43307,Q8N4H5,Q9Y282,P49257,O95140,P49755,P53365,Q9Y6B6,P50897,Q7Z3B4,P40855,Q9UEU0,Q9BVK6,Q5T9L3,O00255,Q9P2W9,O60725,Q9BUN8,Q9BTX1,Q8N5M9,O95070,Q9HD20,P27105,P30536,P40939,Q15041,O60499,O15118,Q96KC8,Q5BJH7,Q9P253,O14925,P55786,P41208,Q96A33,O15127,P46934,Q15070,Q15363,Q9P0J0,Q9Y5J6,P02545,Q5W0Z9,P10619,Q10713,Q15005,Q9Y5M8,P13473,Q969Q5,Q07820,Q12846,P46379,Q9H4A6,Q96RL7,P50402,P11279,P27824,O96008,Q8TB36,O95563,O15400,A6NIH7,Q9Y3E0,Q99623,Q96PC5,Q9UL25,Q9NPA0,Q9NR31,P0CG08,O43615,O15260,Q9Y512,Q9UNL2,Q8TBQ9,Q5J8M3,P04035,O75915,Q92544,Q9NZ43,O43681,P53367,Q8N183,Q86Y82,O75381,P51572,O15504,Q9H0R1,P52789,O60826,Q03519,Q9Y3A6,Q9UBV2 114 +Regulation of phospholipid translocation 0.6012924978926595 1.0777397031469098 0.2811499348499908 1.0 0.56018010973912 2 Q9NV96 1 +Regulation of phospholipid transport 0.6012924978926595 1.0777397031469098 0.2811499348499908 1.0 0.56018010973912 2 Q9NV96 1 +Digestion 0.4889648660006859 1.077126748485688 0.281423644655979 1.0 0.56018010973912 14 Q8WTV0,Q16739 2 +N glycan processing 0.6810005621135512 1.077002987173159 0.2814789311746983 1.0 0.56018010973912 3 Q16706,P14314 2 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.6601091819053626 1.0763377011540278 0.2817762533117167 1.0 0.5604323272087645 5 P07237,Q13162,P13674 3 +Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6007305422871521 1.0751381532236288 0.2823128799894077 1.0 0.5604323272087645 2 P23396 1 +Retinol metabolic process 0.6413145070688927 1.0750249116380115 0.2823635752262941 1.0 0.5604323272087645 6 Q6NUM9,Q8TC12,Q9Y394,Q8NBN7 4 +Deoxyribose phosphate catabolic process 0.5376301799837333 1.0748064733010738 0.2824613816775474 1.0 0.560459300853929 9 Q9H773 1 +Endothelial cell migration 0.3835928353556698 1.073130226214975 0.2832126909291492 1.0 0.5611610685811059 38 Q8WTV0,P42785 2 +Intrinsic apoptotic signaling pathway in response to oxidative stress 0.4669831245399084 1.0676955697795971 0.2856578574954329 1.0 0.5634202045201178 17 O75915,Q9UMX0,Q07820,P23246,Q9UL15,P04179 6 +Regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.4968634529756897 1.0622858301700528 0.2881059451628522 1.0 0.5652470601898916 13 P09601,Q8IWB1 2 +Activin receptor signaling pathway 0.6566280810702232 1.0618921166953816 0.2882846643125429 1.0 0.5652470601898916 5 P36896 1 +Regulation of activin receptor signaling pathway 0.6566280810702232 1.0618921166953816 0.2882846643125429 1.0 0.5652470601898916 5 P36896 1 +Protection from non homologous end joining at telomere 0.6795577937909629 1.06104505137871 0.2886694277436186 1.0 0.5655269477873953 4 Q9NYB0,Q9UBB9 2 +Regulation of phosphatidylcholine metabolic process 0.6561899982507206 1.0600749960647589 0.2891104820293877 1.0 0.565724862659681 5 Q8WTV0 1 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.6764462609596604 1.0584982106100511 0.2898283661306973 1.0 0.5664633705138885 3 O75844 1 +Ether biosynthetic process 0.6556699155980066 1.0579179905919716 0.2900928324299301 1.0 0.566541396506206 5 O00116,Q6IAN0 2 +Regulation of peptidyl lysine acetylation 0.4264241088210627 1.0531186851201102 0.2922866001597848 1.0 0.5678106470798511 24 O75844,Q9NRA0 2 +Activated t cell proliferation 0.6361037595976634 1.0528827042390971 0.2923947539508114 1.0 0.5678106470798511 6 Q9HCL2,P09429 2 +Calcium ion transmembrane transport 0.380970874774458 1.0513933335569878 0.293077976331501 1.0 0.5684656958089913 45 Q4KMQ2,P16615,Q9UMX0,Q9HC07,Q6KCM7,P21796,Q96AQ8,O95202,Q9UM00 9 +Guanine nucleotide transport 0.6743070139033606 1.0498159494923032 0.2938027407777688 1.0 0.5684656958089913 3 P41440 1 +Guanine nucleotide transmembrane transport 0.6743070139033606 1.0498159494923032 0.2938027407777688 1.0 0.5684656958089913 3 P41440 1 +Cyclic gmp amp transmembrane import across plasma membrane 0.6743070139033606 1.0498159494923032 0.2938027407777688 1.0 0.5684656958089913 3 P41440 1 +T helper 1 cell differentiation 0.674239913165191 1.049543723173174 0.2939279427916963 1.0 0.5684656958089913 3 P09429 1 +T helper 1 type immune response 0.674239913165191 1.049543723173174 0.2939279427916963 1.0 0.5684656958089913 3 P09429 1 +Positive regulation of striated muscle cell differentiation 0.6535433070865998 1.0491008415409249 0.294131708849551 1.0 0.5686945155124236 5 Q96TA1,P42345,Q16539,Q15014 4 +Positive regulation of cytoplasmic transport 0.634899644097523 1.047769126134258 0.2947449902386323 1.0 0.5691044881713382 6 Q9UL25,P35241 2 +Positive regulation of early endosome to late endosome transport 0.634899644097523 1.047769126134258 0.2947449902386323 1.0 0.5691044881713382 6 Q9UL25,P35241 2 +Leukotriene metabolic process 0.653208226106982 1.0477119819541785 0.2947713254284902 1.0 0.5691044881713382 5 P09960,O14880,Q99735 3 +Negative regulation of nervous system development 0.4302699989458712 1.0430034640482853 0.2969466884072063 1.0 0.5718114037470943 23 P30536,Q9NQC3,Q8IXJ6 3 +Regulation of epithelial cell migration 0.3802083638309805 1.0398653111445826 0.2984024806800349 1.0 0.5730912101261711 42 P09601,Q8WTV0,P42785 3 +Negative regulation of cysteine type endopeptidase activity 0.4429262493460542 1.035957415455444 0.3002220097952062 1.0 0.5750176333679194 20 P51812,Q15041,Q15392 3 +Heparan sulfate proteoglycan metabolic process 0.6321012827864783 1.0358901684506736 0.3002533848164568 1.0 0.5750176333679194 6 P51688,Q7LGA3,Q99805 3 +T cell homeostasis 0.6316548879723605 1.0339959110207826 0.3011380748095755 1.0 0.5761890312968067 6 Q9HCL2 1 +Macropinocytosis 0.6703204047217582 1.033653998407382 0.3012979457419815 1.0 0.5761890312968067 3 Q9BZG1,P50570 2 +Postsynaptic membrane organization 0.5505024619825327 1.0275752592791956 0.3041496670529149 1.0 0.5786495237956399 8 P49354 1 +Oligosaccharide lipid intermediate biosynthetic process 0.6289893129050861 1.0226887546589651 0.3064550300083297 1.0 0.5810422292608075 6 Q86YN1,Q9BT22,Q2TAA5 3 +Integrated stress response signaling 0.6465954288164519 1.0203283825914309 0.3075727468181028 1.0 0.5818353126988274 5 Q15363 1 +Perk mediated unfolded protein response 0.6465954288164519 1.0203283825914309 0.3075727468181028 1.0 0.5818353126988274 5 Q15363 1 +Membrane fusion 0.3763563376088373 1.018919381616442 0.3082412414884972 1.0 0.5826030849491477 51 Q92599,O60499,Q9UNK0,Q12846,Q969M3,Q9NZ43,P51809,Q9NVJ2,Q9BZG1,Q86Y82,Q9UEU0,O15400,Q9P2W9,O75396,Q9P0L0,Q9BSR8,Q12981,Q9H270,Q8IWA4,Q5SQN1,O95721 21 +Cop9 signalosome assembly 0.6655534338789385 1.0143612499557522 0.3104104074119633 1.0 0.5857049224061854 3 Q99627 1 +Embryonic heart tube development 0.626631042775785 1.012691328871999 0.3112076209178984 1.0 0.5870427202972263 6 Q15363 1 +Fatty acyl coa metabolic process 0.4580783756680886 1.0111878556464553 0.3119265271785538 1.0 0.5880352038385153 17 Q9UMR5,Q53GQ0,Q6Y1H2,P50897,Q9UKU0 5 +Glycerophospholipid catabolic process 0.5860457294917842 1.010124797143712 0.3124355032251227 1.0 0.5886914705445049 7 Q8WTV0 1 +Organophosphate catabolic process 0.3759202868182578 1.0096171802423448 0.3126787352864644 1.0 0.5889830125478122 35 Q10713,Q9H773,Q8NCC3,Q8WTV0,P00813 5 +Negative regulation of telomerase activity 0.6434791746236723 1.0074421902985025 0.3137223252203909 1.0 0.5902166133593408 5 P27544 1 +Glycerolipid catabolic process 0.5463482443238314 1.0074266435343249 0.3137297930105056 1.0 0.5902166133593408 8 Q8WTV0 1 +Dendritic cell migration 0.6433136675296771 1.006758145097392 0.314051012661664 1.0 0.5902166133593408 5 Q4KMQ2,P09429 2 +Release of cytochrome c from mitochondria 0.4702951094244637 1.00362793873294 0.3155579827325165 1.0 0.591451610174564 15 Q96A26,Q9H3K2,P02545,P04179,O60313 5 +Adipose tissue development 0.4958682175473461 1.0010661456311143 0.3167948308412729 1.0 0.5925547763501654 12 P43490,Q6KCM7,O15173 3 +Receptor mediated endocytosis 0.3690675931904019 0.999427396746166 0.3175876936473212 1.0 0.592712656847743 62 P41440,Q14108,Q9UL25,P27824,O75955,Q13432,Q5VW38,P46934,P50897,P05067 10 +Vascular process in circulatory system 0.3747947177684678 0.9993653699350116 0.3176177291111577 1.0 0.592712656847743 35 P30825,P41440,P53985,P42892,P04179,P20020,P33527,P08183,Q96QD8,Q9HB40,Q8WWI5 11 +Centromere complex assembly 0.5139026670939848 0.9986453949350363 0.3179665014061537 1.0 0.5927962069502952 10 P50748,Q9BS16 2 +Cellular response to arsenic containing substance 0.5138671188443988 0.9984600894038432 0.318056308219123 1.0 0.5927962069502952 10 P09601 1 +Mitochondrial fission 0.4753744789470761 0.9973362918550248 0.3186013035051993 1.0 0.593420563903471 14 Q8TB36,Q9UDX5 2 +Protein deneddylation 0.5129244870315954 0.9935467432904028 0.3204435829511416 1.0 0.5961845246127614 10 Q99627,O14656,Q9BT78,Q92905,Q9UNS2 5 +Endocrine process 0.5818844810964927 0.9912977121606388 0.3215402298160321 1.0 0.5978905363022337 7 P22466 1 +Positive regulation of reproductive process 0.5123923353801008 0.9907733174356456 0.3217962810722568 1.0 0.5980324631488044 10 Q8IXJ6 1 +Intestinal absorption 0.5121663423362026 0.9895955826060188 0.3223718300103804 1.0 0.5987676608202851 10 Q8WTV0 1 +Regulation of cell cell adhesion mediated by cadherin 0.6616504035293539 0.9891373481844322 0.3225959466292742 1.0 0.5988496582476487 4 O75955 1 +Positive regulation of cell cell adhesion mediated by cadherin 0.6616504035293539 0.9891373481844322 0.3225959466292742 1.0 0.5988496582476487 4 O75955 1 +Forebrain cell migration 0.493420964136042 0.9875553480473488 0.3233704636437891 1.0 0.5988761063024756 12 Q9NQC3 1 +Positive regulation of tau protein kinase activity 0.5805001404888929 0.981957914888244 0.3261205819314896 1.0 0.6018670196212045 2 P07900 1 +Viral protein processing 0.5190287341388305 0.9804019945835888 0.3268877255854623 1.0 0.6026472345970469 9 P27824,Q10472,P61009,P48729,Q13724 5 +Deoxyribonucleoside triphosphate metabolic process 0.5187890305571516 0.9791872747397408 0.3274874550312496 1.0 0.6033749884631496 9 Q9H773 1 +Triglyceride metabolic process 0.4721478122410139 0.9784006930228316 0.3278761855817493 1.0 0.6033749884631496 14 Q9HCL2,Q8NCG7,Q92604,Q96N66,Q8WTV0 5 +Negative regulation of interleukin 2 production 0.5796572070806321 0.978098416161254 0.3280256511284261 1.0 0.6033749884631496 2 P15311 1 +Golgi vesicle budding 0.6359804908732892 0.9764884914577816 0.3288224482421524 1.0 0.6036726601521447 5 P49755,Q9H4A6,Q15363 3 +Negative regulation of gliogenesis 0.5781307434586874 0.9743321964535367 0.3298916233688165 1.0 0.6053015587315892 7 P30536,Q8IXJ6 2 +Dendritic cell chemotaxis 0.6577346082552182 0.9734766764916428 0.3303164465961667 1.0 0.6059139890015132 4 Q4KMQ2,P09429 2 +Response to nicotine 0.5773589548522582 0.970846277534076 0.3316248337421537 1.0 0.6071425773188536 7 P09601 1 +Endoplasmic reticulum to cytosol transport 0.4805440211838191 0.9694125392222632 0.3323393984978477 1.0 0.6081310183158456 13 Q9GZP9,Q96CS3,P51572,Q8TCT9,Q9BUN8,Q9UBV2 6 +Cerebral cortex cell migration 0.4991634723294261 0.9682369941680816 0.3329260231167446 1.0 0.608854818313255 11 Q9NQC3 1 +Skeletal muscle acetylcholine gated channel clustering 0.6334424198659983 0.9660307764090944 0.3340287810855824 1.0 0.609080544191861 5 P49354 1 +Positive regulation of ion transmembrane transport 0.4084838916730726 0.964968099372281 0.3345607901734655 1.0 0.609666500165502 26 P08183,P22466 2 +Sequestering of actin monomers 0.5765664512503423 0.9639650302805766 0.3350634584375258 1.0 0.6102655528837323 2 Q6IBS0 1 +Embryonic brain development 0.5758307152722539 0.9639461448579454 0.3350729271581003 1.0 0.6102655528837323 7 P27635,Q9Y3C6,O60508 3 +Protein folding in endoplasmic reticulum 0.5157237482550506 0.963659412328091 0.3352167094909555 1.0 0.6103163891178736 9 P07237,Q13217,P27824,Q9P0L0 4 +Positive regulation of leukocyte proliferation 0.4572663405409689 0.9634179627833304 0.3353378154398112 1.0 0.6103163891178736 16 P04439,Q9HCL2,P09429,P00813,P30825 5 +Regulation of vesicle mediated transport 0.3232116905500256 0.9619195776556928 0.3360900034343979 1.0 0.6106139702036357 133 Q9UL25,Q9NR31,Q13432,Q9NRA0,Q12846,Q8WTV0,Q9P253,P11279,P53367,Q08722,P50897,P09601,Q4KMQ2,O75955,P16615,Q9P2W9,P41440,Q9H223,O14656,P05067 20 +Maintenance of protein location in mitochondrion 0.6520126846068643 0.959782436431002 0.3371647236504 1.0 0.611129594496901 3 P30536 1 +Cell cell recognition 0.4687525529774859 0.9584837985600048 0.3378188572921616 1.0 0.6114160459994351 14 P45880,Q12959 2 +Fatty acid transport 0.4426629978662414 0.9581570473164276 0.33798357263496 1.0 0.6114160459994351 18 O43808,P28288,O14678,O43772,P23786 5 +Membrane raft assembly 0.6131236662777102 0.9555610924765372 0.3392940263000406 1.0 0.6132541404200896 6 P41440,O75955 2 +Oligosaccharide metabolic process 0.6129638639972451 0.9548867254845246 0.3396349834293275 1.0 0.6132849345439467 6 O75352,P10253,P17900 3 +Regulation of gliogenesis 0.4677914466628066 0.9528477108756298 0.3406672365955516 1.0 0.6134162355120615 14 P30536,Q8IXJ6 2 +Process utilizing autophagic mechanism 0.3110671551985947 0.952655078581054 0.3407648606770226 1.0 0.6134162355120615 184 Q9NZJ7,P10619,Q9UMX0,P13473,Q93050,P21796,Q969Q5,Q07820,O15118,P12235,Q96RL7,P05141,Q9P253,Q96HY6,Q66K74,P09601,P16615,P04062,P46934,P07602,Q8NHS3,O75844,O14681,P27544,Q99623,Q86UE4,P30536,Q8IXJ6 28 +Regulation of membrane permeability 0.4266747750443739 0.9518976398722534 0.341148896614194 1.0 0.6134162355120615 21 P45880,P05141,P12235 3 +Estrogen metabolic process 0.612214212207449 0.9517237185702156 0.3412371171503776 1.0 0.6134162355120615 6 O95470 1 +Regulation of phospholipid metabolic process 0.4959506174157774 0.9510302691618928 0.3415890103921195 1.0 0.6135694640106762 11 Q8WTV0 1 +Regulation of vasoconstriction 0.649685054744768 0.9504376793700792 0.3418899060370126 1.0 0.6136411943477745 3 P42892 1 +Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.5130284532127619 0.950015352254573 0.3421044519152263 1.0 0.6136411943477745 9 P09601 1 +Positive regulation of exocytosis 0.4482858560957 0.9490452444036308 0.3425976012318341 1.0 0.6136411943477745 17 Q12846,Q9NRA0 2 +Nucleus organization 0.3564296588455779 0.9488746770871797 0.34268435520174 1.0 0.6136411943477745 71 Q5JTV8,Q86XL3,P50402,P20700,O94901,Q9BTX1,O75844,Q9NQC3,Q9UH99,P02545,Q9BTV4,Q8IXJ6 12 +Behavior 0.3371664621024112 0.945910494700364 0.3441942402085556 1.0 0.615434563364467 85 Q92542,O15118,O76024,P04035,Q96RL7,O75915,P22466,P50897,Q96SB3,P04062,O00264,P10253,P54802,P30536,O75844,P51790,P17900,P05067,P04179 19 +Synaptonemal complex organization 0.6093967849087911 0.9398441690976612 0.3472974988379642 1.0 0.6193099825205391 6 P46379 1 +Monocarboxylic acid transport 0.5702610269196575 0.9388278588301484 0.3478191330148603 1.0 0.6197419893477633 7 P53985,P28288,O95563 3 +Response to molecule of bacterial origin 0.3694645188413728 0.938042818242523 0.3482224059626182 1.0 0.6199625766937464 43 P51812,Q86UE4,P30536,Q8WTV0,Q8IXJ6 5 +Regulation of macroautophagy 0.3632025938077498 0.9368945619924964 0.3488127967295533 1.0 0.6202565378977836 62 P09601,Q9UMX0,Q93050,P21796,P04062,P46934,O15118,P27544,P12235 9 +Homeostatic process 0.3134522232134784 0.9366342488472732 0.3489467284581971 1.0 0.6202565378977836 326 Q92542,Q16891,P36896,Q16739,Q96CP7,P0CG08,P13473,Q93050,O15260,P35670,Q07820,O15118,P30519,O76024,Q12846,Q8WTV0,P23786,O15254,Q8N511,P05141,Q92544,O75503,Q8N183,Q96AQ8,Q96ER9,P50897,O95202,Q6P4Q7,Q96A33,P42785,Q9NX40,Q92581,Q8NF37,P09601,Q4KMQ2,Q9P035,Q9HCL2,Q5BJF2,P16615,O95563,P04062,Q6IAN0,P51572,Q9Y6M7,O00767,P10253,Q9UM00,Q9P0S9,P05023,P61916,P49748,P14735,O95067,P06576,Q9HC07,Q8N5M9,Q9NQC3,P52789,Q7L0J3,P05067,P04179,P51790,Q9Y6C9,O14773,Q9HD20,O60826,P30536,P40939,P00813 69 +Regulation of spontaneous synaptic transmission 0.645181470976198 0.9323915904940768 0.3511341892092177 1.0 0.6226480226984662 3 P05067 1 +Spontaneous synaptic transmission 0.645181470976198 0.9323915904940768 0.3511341892092177 1.0 0.6226480226984662 3 P05067 1 +Very long chain fatty acid catabolic process 0.6245608553347535 0.9295221454699344 0.3526185539493256 1.0 0.624601327426363 5 O14678 1 +Pancreas development 0.4734370017750732 0.9290272032331648 0.3528749886356905 1.0 0.624601327426363 13 Q5T9L3 1 +Positive regulation of vascular associated smooth muscle cell apoptotic process 0.643925237585625 0.9273662487407182 0.3537364082666241 1.0 0.6255042554038999 3 P04179 1 +Cholesterol efflux 0.5674455399992115 0.9261495853774389 0.3543682481184507 1.0 0.6257950071679249 7 Q86Y82,O15118,Q8WTV0 3 +Golgi ribbon formation 0.6450202509070802 0.9228201505714304 0.3561009379315927 1.0 0.6272767977593301 4 Q9H4A6 1 +Response to osmotic stress 0.4134831018807898 0.920612323118848 0.3572528660752772 1.0 0.6280215113171538 23 P08183,P30536 2 +Positive regulation of transporter activity 0.4258756405097473 0.9192160293185456 0.3579825885636185 1.0 0.6280215113171538 20 P22466 1 +Vacuolar transport 0.3615124891035754 0.9188463069940244 0.358175967516859 1.0 0.6280215113171538 62 Q9NZJ7,Q14108,Q9P253,P07602,P13473,P46934,O15118,Q96RL7 8 +Regulation of renal system process 0.5664512503512128 0.9179254655990424 0.3586578884857259 1.0 0.6280215113171538 2 Q9Y5X3 1 +Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway 0.5664512503512128 0.9179254655990424 0.3586578884857259 1.0 0.6280215113171538 2 P23634 1 +Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway 0.5664512503512128 0.9179254655990424 0.3586578884857259 1.0 0.6280215113171538 2 P23634 1 +G protein coupled acetylcholine receptor signaling pathway 0.5664512503512128 0.9179254655990424 0.3586578884857259 1.0 0.6280215113171538 2 P29992 1 +Renal sodium excretion 0.5664512503512128 0.9179254655990424 0.3586578884857259 1.0 0.6280215113171538 2 Q9Y5X3 1 +Renal tubular secretion 0.5664512503512128 0.9179254655990424 0.3586578884857259 1.0 0.6280215113171538 2 Q9Y5X3 1 +Positive regulation of renal sodium excretion 0.5664512503512128 0.9179254655990424 0.3586578884857259 1.0 0.6280215113171538 2 Q9Y5X3 1 +Acidic amino acid transport 0.4560267742106045 0.9177958951169584 0.3587257317107646 1.0 0.6280215113171538 15 O75915,O14908,O75746,Q15041,O60831,Q9UJS0 6 +Anterograde neuronal dense core vesicle transport 0.5656083169429521 0.9141048664642132 0.3606617456576408 1.0 0.6304712154850538 2 Q12756 1 +Dense core granule transport 0.5656083169429521 0.9141048664642132 0.3606617456576408 1.0 0.6304712154850538 2 Q12756 1 +Mitochondrial calcium ion homeostasis 0.4796651849520937 0.9117253356436036 0.3619133234024221 1.0 0.6319950583162213 12 Q16891,Q8WWC4,P51572,Q96AQ8,O95202 5 +Negative regulation of establishment of protein localization 0.3911828633768553 0.910603222994407 0.3625044717209467 1.0 0.632222533145367 29 Q9GZP9,Q8N5M9,Q8N183,Q16850,P40939,P04035 6 +Regulation of protein acetylation 0.3980862023169691 0.9096852210207964 0.3629885404648176 1.0 0.6323792504694663 27 O75844,Q9NRA0 2 +Sensory perception of mechanical stimulus 0.4419045137449179 0.9085799595595192 0.3635718889821739 1.0 0.6330640819404415 17 Q9Y6M9,Q14108 2 +Positive regulation of er associated ubiquitin dependent protein catabolic process 0.6389149037232826 0.907361945846728 0.3642154261071746 1.0 0.6340187446359526 3 Q9UMX0 1 +Positive regulation of secretion 0.3637694899075747 0.8976521754095167 0.3693710135226826 1.0 0.6388659831653869 53 P11279,P22466,Q5T9L3,Q9NRA0,Q12846,Q9H4A6 6 +Positive regulation of smooth muscle cell apoptotic process 0.6166761239554032 0.8972380769487263 0.3695918910874138 1.0 0.6388659831653869 5 P04179,O95140 2 +Regulation of body fluid levels 0.3633774929964359 0.8967572908452884 0.3698484424023465 1.0 0.6389775140673977 54 Q4KMQ2,P00403,Q16739,Q9UIJ7,P53582,P04062,P52789,P35670,O76024,P00813,P12814,Q13505,P38435,Q86YV9 14 +Unsaturated fatty acid biosynthetic process 0.4940843744962289 0.8955677106176783 0.3704836874306798 1.0 0.639576897497062 10 O95864,Q9H7Z7,O00767,O15121 4 +Male meiotic nuclear division 0.638054620737576 0.8952099522664133 0.3706748656022332 1.0 0.6397409830349745 4 O15360,Q9Y2W6 2 +Calcium mediated signaling 0.4183519087921429 0.8937514340124686 0.3714548992674031 1.0 0.6405888454585561 21 P16615,P0DMN0,O75844,Q96SB3,P00813 5 +Lactation 0.4669321894979674 0.8921234158202751 0.3723267853042094 1.0 0.6409298386444681 13 P00403,Q86UL3,P52789,P35670,Q13505 5 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.5596661811792762 0.8911944718048018 0.3728248496503168 1.0 0.6412895772610128 7 P04062,P52789 2 +Response to mitochondrial depolarisation 0.5596661811792762 0.8911944718048018 0.3728248496503168 1.0 0.6412895772610128 7 P04062,P52789 2 +Response to ketone 0.364033226089637 0.8864196380128402 0.3753914408133925 1.0 0.6434493689362945 44 Q13126,P04062,Q9NRA0,P16278,P30536,P16435 6 +Negative regulation of natural killer cell mediated immunity 0.6332671916707232 0.8848913222402379 0.3762152487511292 1.0 0.6436278870022532 3 P01889 1 +Interleukin 12 production 0.5570627491382335 0.8795238224960508 0.3791173222582329 1.0 0.6459359394850333 7 P09429,P01889,Q08722,Q07021 4 +Cellular iron ion homeostasis 0.4495307231499907 0.8787943766363833 0.3795127758464507 1.0 0.6462212092414973 15 Q8N511 1 +Myeloid leukocyte differentiation 0.3619704919499323 0.8786776796860463 0.3795760641510162 1.0 0.6462212092414973 36 O00625,Q14739,P04062,Q8N5M9 4 +Regulation of multicellular organism growth 0.4490358838422214 0.8758262949207846 0.3811244729208445 1.0 0.6478629290646795 15 O75844,P05067,Q9HCL2,O95470 4 +Regulation of skeletal muscle tissue development 0.5937850943761898 0.8742805404752327 0.3819654940357297 1.0 0.6486298450645016 6 O75955 1 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.555508350699125 0.872562896442414 0.382901371685195 1.0 0.6493092429602012 7 O95881,O76024 2 +Axis specification 0.4540703003378186 0.8725156058003173 0.3829271583814364 1.0 0.6493092429602012 14 Q8N2A8,Q5T9L3 2 +Mammary gland epithelial cell proliferation 0.6106048263124624 0.8724719188286335 0.3829509810095852 1.0 0.6493092429602012 5 Q9NQC3 1 +Nucleobase containing compound transport 0.3178515969806726 0.871346471181958 0.3835650037452205 1.0 0.6495496774718864 119 Q9HC21,Q86VD7,Q8N1F7,A8CG34,Q6NUK1,P12235,Q8TEM1,P06748,O60282,P05141,Q6KCM7,Q9NPA8,Q08722,Q8TDW0,P41208,Q7Z3B4,Q8TD16,O75955,P22626,Q15388,Q8WYP5,Q92621,Q9UPR3,Q99567,L0R6Q1,Q9BSK2,P67809,O15504,O00159,P12270,Q96MU7,P51991,P41440,Q9BTX1,O43808,Q5JVF3,Q8TB61,Q96FV9,Q9H2D1,Q86V81,P12236,Q13769,Q9UN86,P82979,P37198 45 +Regulation of fat cell differentiation 0.4631138850686707 0.8704953790169812 0.3840297434321869 1.0 0.6499791308599195 13 Q8N4Q0 1 +Inflammatory response 0.3385748820812023 0.8691888048467555 0.3847438697419427 1.0 0.6508567496524221 80 Q9BQE5,P09601,Q8N2K0,Q8NCG7,P22466,Q4KMQ2,O00255,P04062,Q99735,Q6IAN0,Q08722,Q13151,P05067,Q9BWS9,P42785,P00813,Q8IV08 17 +Cell volume homeostasis 0.5174755319838678 0.8680282136749606 0.385378887553081 1.0 0.6512495228734605 8 Q4KMQ2,Q9BXP2,Q96ER9,P51790 4 +Cellular transition metal ion homeostasis 0.4103790799230931 0.866267907803583 0.3863432609870116 1.0 0.6518785423964242 22 P09601,Q8N511,O75880,P35670,O60826,P05067 6 +Protein o linked glycosylation 0.4213414393934803 0.8649139907250535 0.3870859979725702 1.0 0.6524224180957937 19 Q8N4A0,Q10472,Q6ZXV5 3 +Collagen metabolic process 0.4880026007807616 0.8640656273748147 0.3875518398919981 1.0 0.6524224180957937 10 Q92791,P08670 2 +Lipopolysaccharide mediated signaling pathway 0.4959673650458983 0.8639231861078595 0.3876300888280644 1.0 0.6524224180957937 9 Q8WTV0 1 +Regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4709289994680638 0.8637158464702818 0.3877440063595367 1.0 0.6524438323630407 12 Q9UMX0,Q07820,P23246,Q9UL15,P04179 5 +Smooth muscle cell proliferation 0.4205384910816726 0.8595329029303055 0.390046575167873 1.0 0.654668337387691 19 P09601,P09493,P04179,P12956 4 +Regulation of natural killer cell mediated immunity 0.5900248934834441 0.8585654395433535 0.3905803123124114 1.0 0.6550685429534018 6 P01889,P11279,Q9BY67 3 +Digestive system development 0.4602963727932844 0.8545554271761947 0.3927973122585149 1.0 0.6579577430355944 13 Q5T9L3 1 +Regulation of cell death 0.2995228734635083 0.8539617086198678 0.3931262061528584 1.0 0.6582331255940953 370 Q9BXK5,Q86XL3,Q9NZJ7,Q9NS69,Q15041,Q9UMX0,P21796,Q9NRA0,Q9NVI7,P45880,O15118,Q01105,Q07820,O76024,Q12846,P46379,Q6NUK1,Q8IWB1,Q9H4A6,P12235,Q99720,O75915,P22466,P50897,Q15392,P09601,Q9HCL2,Q96A26,Q9H3K2,P0DMN0,P04062,Q13510,P16435,P00403,O60313,P51812,Q12981,O95881,Q9P0J0,Q9NQC3,Q99623,Q9Y6C9,P02545,Q86UE4,P30536,P00813,Q8IXJ6 47 +Regulation of lipase activity 0.4597683078336936 0.8515699065101935 0.3944528481345006 1.0 0.6591827248376796 13 P50897,P16435 2 +Peroxisomal transport 0.5506808437111446 0.8509803777231988 0.3947802529952231 1.0 0.6591827248376796 7 P56589,P28288,O14678,O75381 4 +Bone remodeling 0.4854591604083934 0.8509155257597228 0.3948162796698709 1.0 0.6591827248376796 10 O14773 1 +Protein processing 0.3597909697636452 0.8501446083395233 0.3952446933210063 1.0 0.6595670596918999 49 Q10713,Q9UG56,P42892,O75844,O75503,Q15392,P67812 7 +Positive regulation of calcium ion transport 0.4259837312830088 0.849463595954718 0.3956233786630454 1.0 0.6596083763951529 18 P30536,Q9NRA0 2 +Vesicle cargo loading 0.4499587133144408 0.8485085805192452 0.3961547958900147 1.0 0.6596083763951529 14 Q9NR31,Q15363,Q12770,Q96PC5 4 +Regulation of transport 0.3048514759308411 0.8477409272224943 0.3965822679955748 1.0 0.6596987178522165 348 Q9GZP9,Q9UL25,Q15041,Q00765,Q9UMX0,Q9NR31,Q13432,P0CG08,P21796,Q9NRA0,O15260,O76024,Q16850,Q12846,Q9H4A6,Q96KC8,Q8WTV0,P04035,O75915,P50402,Q9P253,P11279,P22466,P05141,Q12959,Q92544,Q9Y282,P53367,Q08722,Q8N183,P55786,P50897,P08183,P09601,Q4KMQ2,O75955,P16615,Q5T9L3,O95563,P46934,P51572,Q9P2W9,P05023,P41440,Q9H223,O75844,Q8N5M9,P52789,O14656,Q7L0J3,P05067,Q99623,P27105,P30536,P40939,P00813 56 +Interferon gamma production 0.512723864518681 0.8452421535828201 0.3979756510984717 1.0 0.6609752827702344 8 P09429,Q08722,Q07021 3 +Positive regulation of epithelial cell migration 0.3827546934223912 0.8421807867046284 0.3996867666392614 1.0 0.6626375094161142 29 P09601,Q8WTV0 2 +Retina homeostasis 0.6245802611723174 0.8421387246201328 0.3997103075278558 1.0 0.6626375094161142 4 P51790,P04792 2 +Connective tissue development 0.3894489173970483 0.8420079955376181 0.3997834780022737 1.0 0.6626375094161142 27 O75844,Q6KCM7,Q6IAN0,P43490,O15173,P16435 6 +Neutrophil migration 0.4429893585661719 0.8395987780324874 0.4011333846186189 1.0 0.6632592694049908 15 Q8N5M9 1 +Regulation of endoplasmic reticulum unfolded protein response 0.511459639263825 0.8391894258784605 0.4013630201059317 1.0 0.6632905137335424 8 O76024,Q96HY6,P57088 3 +Fatty acid derivative biosynthetic process 0.4243321250432259 0.8387223043285912 0.4016251590475621 1.0 0.6634691931447839 18 Q9UMR5,Q53GQ0,Q6Y1H2,P50897,Q9UKU0 5 +Vesicle docking involved in exocytosis 0.4663544968901021 0.8386414730648429 0.401670530305084 1.0 0.6634691931447839 12 Q9P253,Q9UEU0,P61026 3 +Positive regulation of lipid localization 0.4481534539630972 0.8379801116605954 0.4020418734647841 1.0 0.6637726042907305 14 Q8WTV0 1 +Associative learning 0.4424604297927946 0.8364335913397548 0.4029110217011173 1.0 0.664436219635623 15 O00264,Q13641,P50897,P05067,P04035 5 +Negative regulation of cell killing 0.6229708424239657 0.8358328032868038 0.4032489695181285 1.0 0.664436219635623 4 P01889 1 +Mammary gland epithelium development 0.5469380490542685 0.8342874638741048 0.4041190143608602 1.0 0.6656663920939364 7 Q9NQC3 1 +Intracellular transport 0.3143164967919787 0.8334524673486572 0.4045895946742568 1.0 0.6659766887353893 614 Q9GZP9,Q14108,O60830,Q9NS69,Q8WWC4,Q99595,P28288,P45880,Q8TCT9,Q53H12,P23246,O75964,Q15629,Q03518,P56589,P24390,P43307,Q8N4H5,Q9Y282,P49257,O95140,P49755,P53365,Q9Y6B6,Q7Z3B4,Q14849,P40855,Q9UEU0,Q9BVK6,Q5T9L3,P22626,O43772,Q9P2W9,O60725,Q9BUN8,Q2M389,Q9BSR8,P07602,Q5JVF3,O75844,P35241,O95070,Q9UBX3,P27105,P30536,P07196,Q8NBN3,Q9Y5J9,Q9NZJ7,Q9Y3D6,Q9UGP8,Q15041,Q99797,P36542,O60499,Q14254,Q9UNK0,Q9UJZ1,O15118,P61026,P61009,Q9NPF5,Q5BJH7,Q9P253,O14925,O75503,P55786,P16615,Q5SNT2,P46934,Q15070,Q15363,Q9P0J0,Q9Y5J6,P02545,Q5W0Z9,P10619,Q10713,Q15005,Q9Y5M8,P13473,Q969Q5,Q12846,P46379,P23786,Q96RL7,P50402,P11279,O96008,Q8TB36,Q12770,Q66K74,O15400,Q9UH99,P24539,Q99623,O60313,Q96PC5,Q9UL25,Q00765,Q9NR31,O43615,O15260,Q9Y512,Q9UNL2,Q8TBQ9,Q6NUK1,P12235,P05141,Q92544,Q9NZ43,O14678,O43681,O75431,P53367,Q9UBC2,Q86Y82,Q8NHH9,Q15057,P56385,O94901,O75381,Q9UPR3,P51572,O75947,Q969X5,O15504,Q9UJS0,Q9H0R1,P61916,Q9H223,Q86V81,P52789,O60826,P06576,P05067,Q03519,Q9Y3A6,Q9UBV2 139 +Protein import 0.3228866365808515 0.831905679505653 0.4054621858057956 1.0 0.6670830275741828 92 O60830,Q9NS69,O14925,Q99595,O75381,P13473,O43615,O96008,Q99623,Q9Y512,P02545,P56589,Q7Z3B4 13 +Calcium ion export 0.6213387310454981 0.8294457384980196 0.4068522290692633 1.0 0.6683785693547143 4 O95202 1 +Chromatin remodeling at centromere 0.6198669512569681 0.8236929614656312 0.4101140397533105 1.0 0.6718874314104303 4 O43482 1 +Vesicle targeting 0.3998381597853634 0.8211933620678076 0.411536136925771 1.0 0.6735100442267721 23 Q9NR31,O95772,P49755,Q9Y6B6,Q15363,Q14849 6 +Positive regulation of neurotransmitter uptake 0.543692048328177 0.8157916337858777 0.4146193190351774 1.0 0.6746371935288609 2 P20337 1 +Germ cell migration 0.5436920483281711 0.8157916337858513 0.4146193190351925 1.0 0.6746371935288609 2 P78310 1 +Regulation of response to endoplasmic reticulum stress 0.3990458634945562 0.8154290238540866 0.4148267764792264 1.0 0.6746371935288609 23 P57088,Q9UMX0,O95881,O76024,Q96HY6,P46379,O60313 7 +Response to arsenic containing substance 0.4389299706118125 0.8153249093462456 0.4148863541098642 1.0 0.6746371935288609 15 P09601 1 +Positive regulation of leukocyte migration 0.4207224115551581 0.8152667895713674 0.4149196142920552 1.0 0.6746371935288609 18 Q4KMQ2,Q07021,P09429,Q08722,P05067 5 +Regulation of attachment of spindle microtubules to kinetochore 0.542375441892864 0.8139896670202296 0.4156508704859225 1.0 0.6749993598271361 7 Q96GD4,Q8IXJ6 2 +Actin mediated cell contraction 0.4386887252033076 0.8138837077725101 0.4157115749201163 1.0 0.6749993598271361 15 P05023,Q9UM22,P16615,Q12959 4 +Alcohol catabolic process 0.4526235369308883 0.8112446790722936 0.4172251723138682 1.0 0.6749993598271361 13 Q10713,Q8WTV0 2 +Embryonic skeletal joint development 0.5425681371171633 0.8108093114673496 0.4174751863333408 1.0 0.6749993598271361 2 O95747 1 +Limb joint morphogenesis 0.5425681371171633 0.8108093114673496 0.4174751863333408 1.0 0.6749993598271361 2 O95747 1 +Nephron tubule formation 0.5425681371171633 0.8108093114673496 0.4174751863333408 1.0 0.6749993598271361 2 O95747 1 +Embryonic skeletal joint morphogenesis 0.5425681371171633 0.8108093114673496 0.4174751863333408 1.0 0.6749993598271361 2 O95747 1 +Proximal distal pattern formation 0.5425681371171633 0.8108093114673496 0.4174751863333408 1.0 0.6749993598271361 2 O95747 1 +Lung associated mesenchyme development 0.5425681371171629 0.8108093114673488 0.4174751863333412 1.0 0.6749993598271361 2 Q13308 1 +Epidermis morphogenesis 0.542568137117158 0.8108093114673259 0.4174751863333543 1.0 0.6749993598271361 2 O60568 1 +Morphogenesis of an epithelial fold 0.5425681371171571 0.8108093114673217 0.4174751863333568 1.0 0.6749993598271361 2 Q86V48 1 +Synaptic vesicle clustering 0.5425681371171567 0.8108093114673209 0.4174751863333572 1.0 0.6749993598271361 2 P19022 1 +Detection of muscle stretch 0.5425681371171567 0.8108093114673209 0.4174751863333572 1.0 0.6749993598271361 2 P19022 1 +Response to human chorionic gonadotropin 0.5422871593144132 0.8095647342736438 0.4181903835033553 1.0 0.6756632683211531 2 P48506 1 +Regulation of myelination 0.4519120936746358 0.8072369714016174 0.419529969040231 1.0 0.6762093173722712 13 O75746,Q15058,Q12959,Q8IXJ6 4 +Roof of mouth development 0.5042310676827277 0.8046675304467086 0.4210115613339036 1.0 0.6769345109149864 8 O95470 1 +Adult behavior 0.4090279279547583 0.8040652167154596 0.4213593115556131 1.0 0.6773300044450737 20 Q92542,O75844,O15118,P50897,P51790,P05067 6 +Positive regulation of t cell proliferation 0.4762888900281437 0.803643230857201 0.4216030485227811 1.0 0.6773945649249415 10 Q9HCL2,P09429,P30825 3 +Cellular response to exogenous dsrna 0.5394788528877396 0.801134940180765 0.423053530569875 1.0 0.6785782708947984 7 P41440,O75955,Q7Z434 3 +Mitochondrial translation 0.3546913242906837 0.797475018966985 0.4251752055071844 1.0 0.6792622017631079 46 Q9UGM6,Q07021,Q9Y2Q9,Q8NC60,Q567V2,Q7L0Y3,Q9NWS8,O95182,Q96RP9,Q9Y2R0,Q5T653,P82930,Q9H649,O95900,Q9Y2R9,Q9HD33,Q6PI48,P82912,Q9NX20,Q14197 20 +Positive regulation of endothelial cell migration 0.4043098080390058 0.7958345785984123 0.4261281905172995 1.0 0.6803056450699281 21 Q8WTV0 1 +Phospholipid catabolic process 0.4662855022352161 0.7930276668506179 0.4277617036289081 1.0 0.6818572784791338 11 Q8WTV0 1 +Lymphocyte homeostasis 0.4741253445251637 0.7925261122223017 0.4280539723265302 1.0 0.6821597667224756 10 Q9HCL2,P00813 2 +Cd40 signaling pathway 0.5907429639880073 0.7921268107832005 0.4282867385581617 1.0 0.6822039839886468 5 P35232,Q99623 2 +Positive regulation of phagocytosis 0.5011647291410216 0.7900715129640276 0.4294860053954616 1.0 0.6828068241535589 8 Q4KMQ2,Q12907,Q9NX58,Q08722,P50570 5 +Negative regulation of leukocyte migration 0.4802464920028253 0.7851888845156505 0.4323428316190028 1.0 0.6853600721948496 9 P09601 1 +Positive regulation of natural killer cell mediated immunity 0.6078203766057418 0.7848632012526942 0.4325337795970501 1.0 0.6853600721948496 3 P11279 1 +Positive regulation of natural killer cell mediated cytotoxicity 0.6078203766057418 0.7848632012526942 0.4325337795970501 1.0 0.6853600721948496 3 P11279 1 +Neuron death 0.3212678676978761 0.7844346353869008 0.4327851219889165 1.0 0.6855394737535846 87 Q92542,P09601,Q96A26,P0DMN0,P04062,Q07820,O76024,Q01105,P50897,Q15392,Q99720 11 +Odontogenesis of dentin containing tooth 0.535680753626447 0.7843188813971947 0.4328530230973046 1.0 0.6855394737535846 7 P35613 1 +Positive regulation of autophagy 0.3514387969931553 0.7819793651053858 0.4342267006379012 1.0 0.6868862195763181 36 P09601,P05141,P21796,P27544,Q86UE4,P12235 6 +Regulation of programmed necrotic cell death 0.4787732428626376 0.7778488930595925 0.4366581001968881 1.0 0.6895913316347669 9 Q13510 1 +Positive regulation of cell death 0.3114509650686438 0.7776759606846203 0.4367600674865741 1.0 0.6895913316347669 127 P09601,P22466,Q9NS69,Q96A26,Q9NRA0,Q9Y6C9,P30536,Q8IXJ6 8 +Monocarboxylic acid metabolic process 0.3018396834584455 0.7754434290878248 0.438077681152718 1.0 0.6911823063232192 167 P21796,O15118,Q9UKU0,P23786,O15254,Q8NCG7,A1L0T0,Q8NCC3,Q53GQ0,Q16134,P07099,Q9NZ01,O15121,Q12770,Q8N4Q0,O95864,Q9BRR6,Q9P035,Q9HCL2,Q9H7Z7,O95563,Q92604,Q9NUJ1,Q6Y1H2,O00767,Q9BWD1,P51648,Q13510,Q9HB40,P16435,P49748,O43808,Q15800,Q13011,P40939,O95470 36 +Nuclear membrane organization 0.3890656591309205 0.7747428835693808 0.4384916055253343 1.0 0.6912244938665203 24 Q5JTV8,Q86XL3,P50402,Q9BTV4,Q8IXJ6 5 +Negative regulation of apoptotic signaling pathway 0.3419827137369596 0.7741679510669018 0.4388314780745377 1.0 0.6912244938665203 70 P09601,Q9H3K2,O95881,Q9P0J0,Q07820,O76024,P45880,O60313,Q8IWB1,P02545 10 +Vesicle fusion to plasma membrane 0.5862080151961403 0.7739504469813125 0.4389600955200068 1.0 0.69126347271312 5 Q12846 1 +Meiosis i cell cycle process 0.3863668309968951 0.7736222479380188 0.4391542115850211 1.0 0.6914055543170843 25 Q92791,Q9BTX1,O95067,P46379 4 +Cellular response to ph 0.5335768474290442 0.7711908577631926 0.4405938122925921 1.0 0.6921250974138687 2 P29992 1 +Response to acidic ph 0.5335768474290423 0.7711908577631852 0.4405938122925965 1.0 0.6921250974138687 2 Q99538 1 +Pallium development 0.3517703297844924 0.770743054143644 0.4408592468726355 1.0 0.6921250974138687 41 Q96QD8,Q9NQC3,O14949 3 +Response to xenobiotic stimulus 0.3315619507302322 0.767952450993579 0.4425154343955575 1.0 0.6940702842098598 79 P09601,P22466,O43169,P30536,O15118,P07099,P08183,P40939,P16435 9 +Negative regulation of cell development 0.3768425210714797 0.7676125637524043 0.4427173959944963 1.0 0.6942234378754414 28 P30536,Q9NQC3,Q8IXJ6 3 +Regulation of triglyceride metabolic process 0.5844403403342128 0.7668845798065184 0.4431501426425863 1.0 0.6946622563734691 5 Q96N66,Q8WTV0 2 +Digestive system process 0.4444889715348673 0.7655172924927921 0.4439635732899369 1.0 0.6955220292477708 13 Q8WTV0 1 +Glycerol ether metabolic process 0.5313815582179219 0.7653417133543641 0.4440680910863315 1.0 0.6955220395809688 7 O00116,Q6IAN0 2 +Response to atp 0.5313290250070121 0.7613565397959604 0.4464441383440425 1.0 0.6976017235688196 2 Q96RD7 1 +T cell differentiation in thymus 0.4432752543319381 0.7587141087179835 0.4480235952123639 1.0 0.6994128609285202 13 O96005,P04062 2 +Response to water 0.5304860915987646 0.7576762902016821 0.448644796309039 1.0 0.6998900889443634 2 P23634 1 +Response to hydrostatic pressure 0.5304860915987646 0.7576762902016821 0.448644796309039 1.0 0.6998900889443634 2 P23634 1 +Triglyceride biosynthetic process 0.5290804162605429 0.7552107444906182 0.4501225428327871 1.0 0.7012197340077952 7 Q92604,Q8WTV0 2 +Cerebellar cortex development 0.4288397053759021 0.7551994279009213 0.4501293318829904 1.0 0.7012197340077952 15 P04062,O14949 2 +T cell mediated cytotoxicity 0.5284264885543271 0.7523352844678469 0.4518494538775033 1.0 0.702747865285063 7 P01889,O15400,Q9BY67 3 +Sulfur compound biosynthetic process 0.349913910105892 0.7518486959798405 0.4521420538030811 1.0 0.7030386373970806 49 Q8NCH0,Q9UMR5,O43505,Q8TB61,Q13126,O95563,Q53GQ0,Q6Y1H2,Q9NZ01,P50897,Q8N6G5,Q9UKU0 12 +Metal ion homeostasis 0.3172195897735254 0.7514591397152711 0.4523763825771654 1.0 0.7030744572748798 91 Q9Y3D6,Q16891,Q8WWC4,P35670,O76024,P30519,Q8N511,Q96TC7,Q96AQ8,O95202,Q6P4Q7,Q96A33,O75880,P09601,P16615,P51572,Q9UM00,O43819,P05023,Q9HC07,P09429,Q7L0J3,Q9Y639,O60826,Q9HD20,P05067,P04179 27 +Leukocyte migration 0.3484645352446656 0.7471031497023255 0.4550012991035328 1.0 0.7045290164312232 55 P09601,P35613,P04062,Q8N5M9,Q9H4A6,P00813 6 +Regulation of leukocyte mediated immunity 0.3465519651318353 0.7416825353787829 0.4582797037057804 1.0 0.708080198111627 35 P09601,P11279,O15400,Q9NRA0,Q12846 5 +Ire1 mediated unfolded protein response 0.5256433280306425 0.7401150453911014 0.459230190223503 1.0 0.7089252878537259 7 Q96HY6,P57088 2 +Photoreceptor cell maintenance 0.5960776504842029 0.7395080170342782 0.45959857338487 1.0 0.7092001733271571 3 P51790 1 +Nucleobase containing small molecule biosynthetic process 0.5249972954261806 0.7372826971782599 0.4609504522308201 1.0 0.7105919063229343 7 Q13126 1 +Cell cell adhesion mediated by cadherin 0.5603924378833526 0.7360938021829405 0.4616736143376423 1.0 0.711377148279002 6 O75955 1 +Negative regulation of lymphocyte mediated immunity 0.5969606932916446 0.7350961087145919 0.4622809640407239 1.0 0.7120964016797626 4 P04439,P01889 2 +Peroxisome organization 0.438862542447196 0.7340279100044824 0.4629317280119309 1.0 0.7126557136061532 13 Q9Y3D6,P50542,O75381,Q7Z434,P28288,O14678,P56589,P40855 8 +Regulation of fatty acid biosynthetic process 0.4696507792053264 0.7325757885705895 0.4638172024855285 1.0 0.7132360391532567 9 Q92604,P49748,Q12770 3 +Membrane repolarization 0.4878575330441663 0.7271149774973428 0.4671555243737884 1.0 0.7156814030173945 8 O75844 1 +Muscle adaptation 0.406722603127132 0.7246502990142141 0.4686665929871951 1.0 0.7164816378448126 18 P09601,P16615 2 +Body fluid secretion 0.4126365908854783 0.7239809019376444 0.469077459968422 1.0 0.7164816378448126 17 P35670,Q13505,P00403 3 +Regulation of response to oxidative stress 0.3902062286757811 0.7229055380037877 0.4697379209211847 1.0 0.7170376591624443 22 Q9UMX0,Q07820,P23246,Q9UL15,P00374,P04179 6 +Nuclear membrane reassembly 0.4367895980645676 0.7224589113920835 0.4700123785165311 1.0 0.7170376591624443 13 Q8IXJ6 1 +Regulation of organic acid transport 0.4449675968199486 0.7222492661243682 0.470141238682638 1.0 0.7170376591624443 12 O75915,Q7L0J3,Q15041 3 +Bleb assembly 0.5935849496750057 0.7222061258364901 0.4701677576317675 1.0 0.7170376591624443 4 Q9NR77 1 +Positive regulation of small molecule metabolic process 0.4172830335655433 0.7178588678898485 0.4728443116662617 1.0 0.7200867034642957 16 Q92604,Q12770,P16435,P00403 4 +Embryonic axis specification 0.4856360194128702 0.7166734799952335 0.4735755932390098 1.0 0.720540826018658 8 Q8N2A8 1 +Natural killer cell mediated immunity 0.451665410734485 0.7160914278667364 0.4739348964898986 1.0 0.7209226825463486 11 P04439,P11279,P01889,Q9NVJ2,Q9BY67 5 +Superoxide anion generation 0.5713181988780196 0.7147963293355799 0.4747349036666775 1.0 0.7214799689202418 5 P04179 1 +Histone deacetylation 0.3480555984430646 0.71412001383789 0.4751529712400633 1.0 0.7215797101718231 34 Q9NRA0 1 +Kinetochore organization 0.4850631585752256 0.7139844195931174 0.475236813761525 1.0 0.7215797101718231 8 P50748 1 +Regulation of ire1 mediated unfolded protein response 0.5541965561674452 0.710861230577632 0.4771702327001752 1.0 0.7229902231773816 6 Q96HY6,P57088 2 +Organophosphate biosynthetic process 0.2953598609668603 0.7106909524376293 0.4772757674771701 1.0 0.7229902231773816 176 Q13232,Q10713,Q9NRA0,Q8WVC6,O75964,Q9H490,Q9UKU0,Q5H8A4,Q9UMR5,Q9UG56,Q53GQ0,P50897,Q9NZ01,Q8NF37,Q9BTU6,Q9HCL2,Q9NUQ2,O95563,Q6IAN0,Q92604,P43490,Q6Y1H2,O43292,Q86YN1,P00403,Q8TB61,Q9UIJ7,Q9NPH0,Q96N66,Q92643,P00813 31 +Purine nucleoside biosynthetic process 0.5541450760332287 0.7106522177334682 0.4772997762078601 1.0 0.7229902231773816 6 Q13126 1 +Regulation of cation channel activity 0.3952728393290524 0.7105579103876776 0.4773582330039692 1.0 0.7229902231773816 20 P27105,P22466,Q9UMX0 3 +Positive regulation of transmembrane transport 0.3558542978792066 0.709972198911272 0.4777213763771002 1.0 0.723185811938906 32 P08183,P22466 2 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.4157740291864513 0.7086864873313112 0.478519052103854 1.0 0.723185811938906 16 Q9NZJ7,Q96A26 2 +Intestinal epithelial cell differentiation 0.5189660016858636 0.7078215416032007 0.4790560872386049 1.0 0.7232573186417686 2 P04818 1 +Intestinal epithelial cell development 0.5189660016858636 0.7078215416032007 0.4790560872386049 1.0 0.7232573186417686 2 P04818 1 +Positive regulation of vascular permeability 0.5186850238831051 0.7066163875747943 0.4798049022313526 1.0 0.7232654729427602 2 Q07157 1 +Regulation of blood brain barrier permeability 0.5186850238831051 0.7066163875747943 0.4798049022313526 1.0 0.7232654729427602 2 Q07157 1 +Positive regulation of blood brain barrier permeability 0.5186850238831051 0.7066163875747943 0.4798049022313526 1.0 0.7232654729427602 2 Q07157 1 +Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.4641976489003237 0.7056744093713341 0.4803906387740593 1.0 0.7236834345931273 9 O95881,O76024 2 +Mitochondrial gene expression 0.3421076520194102 0.7054431483486991 0.4805344999950458 1.0 0.7236834345931273 61 Q07021,Q9Y2R0,P82912,Q9Y2R9,Q9Y2Q9,O00411,Q5T653,Q567V2,Q9UGM6,P82930,Q9BSK2,Q9Y2Z2,Q9NWS8,O95900,Q969Z0,O95182,Q9HD33 17 +Oocyte differentiation 0.4411607960558587 0.7017169813143356 0.4828556807492479 1.0 0.7255372669646071 12 Q8N2A8 1 +Positive regulation of b cell proliferation 0.5677781171273728 0.7008628719567683 0.4833885968968705 1.0 0.7256988604037014 5 P00813,P14174 2 +Regulation of hormone secretion 0.3547876717427604 0.700845553105793 0.4833994061862672 1.0 0.7256988604037014 32 P22466,O95563,Q8N5M9,Q12846,P40939 5 +Regulation of blood circulation 0.3683606600513839 0.7002756075325839 0.4837552019780868 1.0 0.7260692082012107 28 P05023,P16615,Q12959,P42892,P09493,O75844,P00813 7 +Xenobiotic metabolic process 0.419145429343173 0.6977951346884129 0.4853053222089269 1.0 0.726757217470579 15 P07099,P16435,O43169 3 +Feeding behavior 0.4551746525791375 0.6958875280063512 0.4864992685328484 1.0 0.7275644441236425 10 P05067,P22466 2 +Positive regulation of endocytosis 0.3825288565349675 0.6956701843951698 0.4866354017713243 1.0 0.7275644441236425 23 Q4KMQ2,P41440,O75955,Q9UL25,P50897 5 +Synaptic signaling 0.3091712879994052 0.694056479368481 0.487646789989139 1.0 0.7281331360506439 99 Q92542,P41440,Q9P253,Q9NR77,O75955,P16615,Q12959,P51812,Q8NCG7,Q13432,O14656,Q7L0J3,P50897,Q12846,Q5SQN1,Q9UQB8,P51790,Q96SB3 18 +Ketone biosynthetic process 0.5499528976742241 0.69366866304143 0.4878900225080786 1.0 0.7282536688795187 6 Q14849 1 +Deoxyribonucleoside triphosphate catabolic process 0.5494808075951804 0.6917607791537413 0.4890875708777757 1.0 0.7287451402800262 6 Q9H773 1 +Nucleoside triphosphate catabolic process 0.5494808075951804 0.6917607791537413 0.4890875708777757 1.0 0.7287451402800262 6 Q9H773 1 +Embryo implantation 0.4542868951414889 0.6913981450033471 0.4893153695094281 1.0 0.7287451402800262 10 P35613,P36896 2 +Lymphocyte apoptotic process 0.4068348648774866 0.6877277524785107 0.4916242399868706 1.0 0.7311194004720949 17 P24390,P00813 2 +Carbohydrate derivative metabolic process 0.3055411990062475 0.686810390568346 0.4922022211639212 1.0 0.7316519503788018 281 Q13232,Q16739,Q9UKK9,Q9NRA0,Q8WVC6,O15118,O75964,P16278,Q9H490,Q9H4A6,Q9UKU0,Q5H8A4,Q8NCH0,Q9UMR5,Q12959,Q9H773,Q53GQ0,Q10472,P50897,Q9NZ01,Q99805,Q9BRR6,Q9HCL2,Q2TAA5,P0DMN0,O95563,P04062,Q9NUJ1,Q6Y1H2,O43292,Q86YN1,Q9BT22,O60725,P24539,P54802,P00403,Q8N4A0,O43505,Q8TB61,Q9UIJ7,P46977,Q9HC07,Q13126,Q7LGA3,Q6ZXV5,Q9NPH0,P17900,O60313,Q8N6G5,Q92643,P00813,Q9Y287 52 +Regulation of protein tyrosine phosphatase activity 0.5133464456307872 0.6838229341712704 0.4940869827027663 1.0 0.7334706379404216 2 P04899 1 +Cardiac muscle cell membrane repolarization 0.5468044729330286 0.6809631956232299 0.4958947788797587 1.0 0.7348384095679106 6 O75844 1 +Regulation of dna binding 0.3627571141402514 0.6803284718456492 0.4962965004234307 1.0 0.7349473098170743 29 P09601,O75844 2 +Positive regulation of dna damage response signal transduction by p53 class mediator 0.579539066891518 0.676685402667835 0.4986055800707725 1.0 0.7365638480290767 3 O43324,P61254 2 +Exit from mitosis 0.4194199550689865 0.6718725834179206 0.5016648156555175 1.0 0.739368706655841 14 P50748,Q99623,Q8IXJ6 3 +Multicellular organismal signaling 0.3792154356606224 0.6717748629753942 0.5017270337499369 1.0 0.739368706655841 23 O75844,P04062,P16615 3 +Positive regulation of attachment of spindle microtubules to kinetochore 0.5600574109868435 0.6706680655339267 0.5024320109264397 1.0 0.7397533258220037 5 Q8IXJ6 1 +Semaphorin plexin signaling pathway involved in neuron projection guidance 0.5790100573969341 0.6671274346299835 0.504690737499907 1.0 0.7403261844101052 4 P42892 1 +Positive regulation of immune effector process 0.3401649685833382 0.66671651165854 0.504953229856492 1.0 0.7405031781856029 39 P09601,P11279,O15400,Q9NRA0,Q99623,Q12846 6 +Positive regulation of myoblast fusion 0.5589207076729535 0.6662460294446763 0.5052538562138333 1.0 0.7405031781856029 5 P41440,O75955,Q9H4M9 3 +Regulation of myoblast fusion 0.5589207076729535 0.6662460294446763 0.5052538562138333 1.0 0.7405031781856029 5 P41440,O75955,Q9H4M9 3 +Regulation of the force of heart contraction 0.5577956642400179 0.6618755170846535 0.5080510035637049 1.0 0.742441683951791 5 P05023,P16615 2 +Glycosyl compound biosynthetic process 0.4735659764426391 0.6603425886688105 0.5090340055931137 1.0 0.7430623617508603 8 Q13126 1 +Positive regulation of mitochondrial membrane potential 0.5766216639862634 0.6581973898307351 0.5104113018263867 1.0 0.7440935845902745 4 Q9UJZ1 1 +Insulin secretion 0.3565216180602819 0.65599424362534 0.5118278279866666 1.0 0.7446676737390753 30 P22466,O95563,Q8N5M9,Q12846,P40939 5 +Exocytosis 0.3171453960330148 0.6558865597358002 0.5118971165407857 1.0 0.7446676737390753 83 P09601,Q9P253,P11279,Q9UL25,P16615,Q9BRK5,Q8N5M9,Q9NRA0,Q7L0J3,O43760,Q12846,Q5SQN1 12 +Regulation of receptor binding 0.5753550123859071 0.6534731190153686 0.5134513136390984 1.0 0.7460739066087773 4 P16615 1 +Protein localization to golgi apparatus 0.4534286204470534 0.6529636829317285 0.5137796918076281 1.0 0.7461286828854267 9 Q8TD16,P40616,P49755,Q9H4A6,Q96RL7 5 +Cobalamin metabolic process 0.5550425342607344 0.6512066539375075 0.5149130956457881 1.0 0.7470561699417311 5 O14678 1 +Positive regulation of protein localization to cell periphery 0.3799834168550733 0.6508099730408288 0.5151691615634588 1.0 0.747264771186752 22 O00264,O15258,Q12846,Q12959 4 +Myeloid leukocyte migration 0.3643874273585182 0.64656240224801 0.5179151979782342 1.0 0.74891911397424 27 Q4KMQ2,P35613,O00255,P09429,Q8N5M9,Q08722 6 +Synaptic vesicle priming 0.5538337826354982 0.6465345774727715 0.5179332115055268 1.0 0.74891911397424 5 Q7L0J3 1 +Bradykinin catabolic process 0.5729082733567119 0.64437079738101 0.5193350164920854 1.0 0.7498751431448966 4 P42892 1 +Regulation of potassium ion import 0.5727748183568608 0.6438752170606498 0.5196563536337104 1.0 0.7501763630005082 4 P05026,Q12959 2 +Snorna localization 0.5699831365935981 0.641030155411155 0.5215030909310756 1.0 0.7513761772654872 3 P22087,Q8WWY3 2 +Pigment biosynthetic process 0.3707056834550078 0.6389981695418805 0.5228241226774057 1.0 0.7521845894263095 24 P22830,Q9P0S9,O00264,P30536 4 +Heterotypic cell cell adhesion 0.4437481050194473 0.6384151983210818 0.5232034400866805 1.0 0.7521845894263095 10 Q08722,P41440,O75955 3 +Cellular response to oxygen radical 0.5688806009996574 0.636949547930254 0.5241577071429449 1.0 0.7525007802711826 3 P00374 1 +Response to oxygen radical 0.5688806009996574 0.636949547930254 0.5241577071429449 1.0 0.7525007802711826 3 P00374 1 +Cytokine production involved in immune response 0.4087305568083333 0.6366381390124837 0.524360576526679 1.0 0.7525007802711826 15 Q9NRA0 1 +Negative regulation of receptor signaling pathway via stat 0.5021073335206463 0.6365276733138672 0.5244325497968061 1.0 0.7525007802711826 2 O14964 1 +Negative regulation of receptor signaling pathway via jak stat 0.5021073335206463 0.6365276733138672 0.5244325497968061 1.0 0.7525007802711826 2 O14964 1 +Immune response regulating signaling pathway 0.3349265961881265 0.6341676003126715 0.5259714496043466 1.0 0.7535629138749274 62 O43657,O75955,Q9NPR9,Q9UMX0,P51812,Q9H078,Q9NQC3,Q08722,P46379,P00813 10 +Intrinsic apoptotic signaling pathway 0.3180232579166523 0.6339952939434353 0.5260838933563745 1.0 0.7535629138749274 81 P07237,P09601,Q9Y3D6,O75915,Q9UMX0,O95881,Q9P0J0,Q9NYF8,P45880,Q07820,O76024,P51572,P23246,Q9UL15,P46379,Q9Y4L1,P04179,O60313 18 +Response to hydrogen peroxide 0.3569932596061654 0.6339613113365722 0.5261060711884336 1.0 0.7535629138749274 29 Q99720 1 +Copi coated vesicle budding 0.5698044841760903 0.632869458537647 0.5268188936877629 1.0 0.7538120269817377 4 Q15363,P49755 2 +Protein ufmylation 0.5688781797948638 0.6294470026011499 0.5290564546157044 1.0 0.7558760638616386 4 Q96HY6 1 +Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway 0.5666104553119795 0.6285700331844484 0.5296305840632867 1.0 0.7561265396879495 3 P23634,P49840 2 +Regulation of xenophagy 0.4995785332958589 0.6260245122081316 0.5312988636107854 1.0 0.7570578502715701 2 Q6UWE0 1 +Adenylate cyclase modulating g protein coupled receptor signaling pathway 0.3907842219493185 0.6225022461544851 0.533611667275613 1.0 0.7583142527694223 18 P07602 1 +Arachidonic acid metabolic process 0.5307171638964974 0.616775118215093 0.5373830659357588 1.0 0.7612293516450384 6 Q9H7Z7,Q8NCG7,P07099 3 +Regulation of cardiac conduction 0.5460436553726692 0.6166082956479572 0.5374931214695771 1.0 0.7612293516450384 5 P16615,Q6PI78 2 +Myeloid leukocyte activation 0.3713299339344174 0.6151505529116541 0.5384552993178546 1.0 0.7617074286777116 23 P09601,Q9NRA0 2 +Regulation of cysteine type endopeptidase activity 0.3356303896355735 0.613334551405117 0.5396551519168964 1.0 0.7627294193732319 54 Q9NZJ7,Q15041,Q96A26,P51812,Q9P0J0,Q15392,P16435 7 +Gliogenesis 0.3346102578610669 0.6131614869823034 0.5397695673519267 1.0 0.7627294193732319 58 P04062,Q9NQC3,P30536,Q96N66,Q8IXJ6 5 +Positive regulation of protein glycosylation 0.4959258218600606 0.6109485261778617 0.5412336578124617 1.0 0.7634400154179594 2 Q9UHD1 1 +Regulation of protein glycosylation 0.4959258218600606 0.6109485261778617 0.5412336578124617 1.0 0.7634400154179594 2 Q9UHD1 1 +Endothelial cell proliferation 0.3804265294933433 0.61057403243975 0.5414816182123869 1.0 0.7635160935725093 20 P09601,Q8WTV0 2 +Granulocyte migration 0.3830243648490824 0.610347289352209 0.5416317772736012 1.0 0.7635160935725093 19 Q8N5M9 1 +Membrane protein ectodomain proteolysis 0.4445003888917798 0.609745701404619 0.5420302754862947 1.0 0.7635926086708915 9 Q92542,Q8TCT9,Q8TCT8,Q9NZ08 4 +Synaptic vesicle exocytosis 0.3802545720324051 0.6094236346318702 0.5422436760122968 1.0 0.7637315690712879 20 P16615,Q9P253,Q7L0J3,Q12846 4 +Receptor clustering 0.4039442695535059 0.6087491486961717 0.5426907241784917 1.0 0.7641814768451919 15 P49354,Q12959 2 +Response to wounding 0.3073323007338695 0.6078311098396818 0.5432994937971214 1.0 0.7642473034091212 88 P09601,Q4KMQ2,Q9UIJ7,P53582,P09493,P12814,P42785,P10586,O14656,Q99623,P04179,Q96G23,P00374,P30536,Q8WTV0,P38435,Q86YV9 17 +Negative regulation of myelination 0.4950828884517987 0.6074858233443436 0.5435285480143306 1.0 0.7642473034091212 2 P53634 1 +Negative regulation of nervous system process 0.4950828884517987 0.6074858233443436 0.5435285480143306 1.0 0.7642473034091212 2 P53634 1 +Protein kinase c signaling 0.5271695008950217 0.6028004713492586 0.5466414331685332 1.0 0.7660346889316885 6 Q9NRA0 1 +Leukocyte homeostasis 0.414179028956701 0.5977097074075345 0.5500336470700051 1.0 0.7686841497796901 13 O95067,Q9HCL2,P00813 3 +Intermediate filament bundle assembly 0.5574044317033656 0.5949127959865458 0.5519017634266417 1.0 0.7703914347484736 3 P07197 1 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.5400990408143047 0.5939980366175068 0.5525134261652198 1.0 0.7703914347484736 5 Q5JVF3,P12270 2 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.4134604333310448 0.5937963805664077 0.5526483101757498 1.0 0.7703914347484736 13 O43657,Q9H078 2 +Regulation of translational initiation by eif2 alpha phosphorylation 0.5589676235360099 0.5931325319730275 0.5530924603370981 1.0 0.7703914347484736 4 Q15363,Q13217 2 +Regulation of cell activation 0.321357005458859 0.5920773317454583 0.5537988055807879 1.0 0.7705479931298648 75 P09601,P11279,O96005,P22466,Q12959,Q9HCL2,Q9NRA0,Q08722,Q12846,P00813,P30825 11 +Regulation of phospholipase activity 0.4338765665257347 0.5893774476475383 0.5556081016734267 1.0 0.7717745599325099 10 P50897 1 +Phosphatidylinositol 3 kinase signaling 0.3947704714470722 0.5823052080566995 0.5603611180893888 1.0 0.7761088950853033 16 Q8IXJ6,P46934 2 +Positive regulation of telomere capping 0.5364848660640392 0.5803533244436808 0.5616763743821713 1.0 0.7767921551843483 5 Q96T60,Q96GD4 2 +Leukocyte mediated cytotoxicity 0.3989948737694942 0.580075141763822 0.561863946309964 1.0 0.7767921551843483 15 P04439,P11279,P01889,O15400,Q9NVJ2,Q9BY67 6 +Peptide transport 0.3298425783159326 0.579554803905229 0.5622148789397676 1.0 0.7768455978354584 37 P22466,O95563,Q8N5M9,Q8N183,Q12846,P40939,Q03519 7 +Sarcoplasmic reticulum calcium ion transport 0.520278436247275 0.5758618209334219 0.5647085834165286 1.0 0.7788981682936275 6 O75844 1 +Positive regulation of cytokinesis 0.4101563719183937 0.5758511422523517 0.5647158019559357 1.0 0.7788981682936275 13 O14908,Q15058,Q9H0H5,Q7Z7K6,Q96GD4,P37198 6 +Positive regulation of nucleotide metabolic process 0.51954554806054 0.573013477277927 0.56663556872686 1.0 0.7805753901629587 6 P05067,P00403 2 +Positive regulation of atp metabolic process 0.51954554806054 0.573013477277927 0.56663556872686 1.0 0.7805753901629587 6 P05067,P00403 2 +Paraxial mesoderm development 0.5508712759977583 0.5713608459232812 0.5677550643807796 1.0 0.7816321790347721 3 Q8WUM0,Q8NBL1 2 +Regulation of intracellular lipid transport 0.4858106209609402 0.5698203009649206 0.5687995849579366 1.0 0.7822662430964358 2 P22307 1 +Positive regulation of intracellular lipid transport 0.4858106209609402 0.5698203009649206 0.5687995849579366 1.0 0.7822662430964358 2 P22307 1 +Heat acclimation 0.4855296431581869 0.568691479315019 0.5695655312535863 1.0 0.7822662430964358 2 Q16576 1 +Neuromuscular process 0.3515771712008097 0.5680731262271105 0.5699853147314631 1.0 0.7822662430964358 28 O75844,P04062,O14773 3 +Positive regulation of fatty acid oxidation 0.4852486653554375 0.5675634198105317 0.5703314517661413 1.0 0.7822662430964358 2 P50416 1 +Positive regulation of fatty acid beta oxidation 0.4852486653554375 0.5675634198105317 0.5703314517661413 1.0 0.7822662430964358 2 P50416 1 +Peripheral nervous system myelin maintenance 0.4852486653554245 0.5675634198104794 0.5703314517661768 1.0 0.7822662430964358 2 Q15149 1 +Positive regulation of protein secretion 0.3586960611047773 0.5663520314388618 0.5711544964309727 1.0 0.7830723472905076 25 Q9H4A6,Q12846,Q5T9L3 3 +Embryonic pattern specification 0.4353198496874084 0.5658385302509815 0.5715035512725541 1.0 0.7832809386121311 9 Q8N2A8 1 +Nucleoside phosphate catabolic process 0.3816868101281573 0.5648954289463058 0.5721448929905502 1.0 0.783784327470587 18 Q9H773,P00813 2 +Regulation of nik nf kappab signaling 0.3814601022679356 0.5634677840782537 0.5731163913372648 1.0 0.7843079548323045 18 Q99623,O43657,Q12959 3 +Telencephalon development 0.3304094185467894 0.562448652336298 0.5738103788384099 1.0 0.784643283416689 44 Q96QD8,Q9NQC3,O14949 3 +Negative regulation of cell activation 0.3601836106761765 0.5620587481201557 0.5740759931076314 1.0 0.784643283416689 24 P09601,P22466 2 +Regulation of translation in response to stress 0.421643641927929 0.561453400841767 0.5744884888979813 1.0 0.7848944556797507 11 P51812 1 +Response to corticosteroid 0.3503748627241458 0.5586771008475245 0.5763821101234834 1.0 0.7858682529956529 28 P04062,P16435 2 +Tumor necrosis factor superfamily cytokine production 0.3690985014430932 0.5534801864614948 0.5799346443065558 1.0 0.7888785174750558 21 P30536,Q9NRA0 2 +Negative regulation of endoplasmic reticulum unfolded protein response 0.5291835986320341 0.5530371588967392 0.5802379657319916 1.0 0.7888785174750558 5 O76024 1 +Positive regulation of triglyceride metabolic process 0.5455298216522999 0.5523239204527387 0.5807264447561316 1.0 0.7889384649306077 3 Q8WTV0 1 +Regulation of neurotransmitter transport 0.3791127735973526 0.5487106788823236 0.5832040164653838 1.0 0.7914401977114863 18 P41440,Q9P253,O75955,P16615,O14656,Q4J6C6 6 +Protein localization to organelle 0.2879179491258295 0.5467666552013968 0.5845390542585709 1.0 0.7926054209638935 362 Q9P0I2,Q5JTV8,Q14108,O60830,Q9NS69,Q10713,Q99595,Q15005,Q9Y5M8,Q8N4V1,P13473,Q9NPA0,O43615,Q96GD4,Q9Y512,Q9UNL2,Q53H12,P46379,Q15629,P56589,Q5J8M3,Q9H4A6,Q96RL7,Q8WWC4,Q8N766,P24390,P11279,O14925,Q12959,P49257,Q8N4H5,O43681,O95140,O96008,P49711,P49755,P55786,Q8TB36,Q96HY6,Q96SB3,Q96A33,Q7Z3B4,O94901,O75381,P50748,P46934,P51572,O43292,Q9UH99,Q15070,P02545,Q9P0J0,Q9Y5J6,P52789,Q9NQC3,O14656,Q99623,Q9Y6C9,O14773,O15258,P30536 61 +Regulation of neuron projection regeneration 0.5455356598208752 0.5448696259260883 0.5858431879000552 1.0 0.7935072284829346 4 Q96G23 1 +Pyrimidine ribonucleoside triphosphate metabolic process 0.4308708920440174 0.5447780128206478 0.5859062025024748 1.0 0.7935072284829346 9 Q9UIJ7 1 +Anterior posterior pattern specification 0.3645146488406537 0.5429315085396653 0.5871769608174588 1.0 0.7941881052006452 22 Q8N2A8,Q5T9L3 2 +Cysteine metabolic process 0.542439572793711 0.541404221082882 0.5882289984013422 1.0 0.7949939266984439 3 P48506,P25325 2 +Positive regulation of sequestering of triglyceride 0.4779432424838448 0.5385080701522271 0.5902263351555601 1.0 0.7964225994444956 2 O60664 1 +Regulation of leukocyte migration 0.3389110784614368 0.5378385639040615 0.5906885056562814 1.0 0.79663529989975 31 Q4KMQ2,P09601,Q07021,P09429,P05067,Q08722,Q5JRA6,P00813 8 +Regulation of lipid transport 0.371874888286514 0.5377595210568846 0.5907430811427898 1.0 0.79663529989975 19 P22466 1 +Regulation of nucleotide metabolic process 0.3824130437942171 0.5372940956859215 0.5910644832050513 1.0 0.7968313356658413 17 Q9NRA0 1 +Purine containing compound biosynthetic process 0.3100174814560124 0.5356311139436893 0.5922135208062036 1.0 0.7978099151751589 81 Q13232,Q9UMR5,Q8TB61,Q9UIJ7,Q13126,O95563,Q9NRA0,Q53GQ0,Q8WVC6,Q6Y1H2,P50897,Q9NZ01,O75964,Q9UKU0,P00813,P00403 16 +Bone mineralization 0.4224460746741992 0.5334436848659538 0.593726484300348 1.0 0.7988778311805128 10 O75844 1 +Regulation of short term neuronal synaptic plasticity 0.4762573756673212 0.5318801546305567 0.5948090029943462 1.0 0.799517240979116 2 Q96A49 1 +Action potential 0.3658715224164999 0.5316708491936082 0.5949539851484593 1.0 0.799517240979116 21 P04062,P16615,Q12959 3 +Thymus development 0.4450738579476946 0.5307274805849653 0.5956076399854422 1.0 0.799517240979116 8 O75844 1 +Regulation of t cell proliferation 0.3762417160425864 0.5307247543027509 0.5956095294857304 1.0 0.799517240979116 18 P30825,Q12959 2 +Tolerance induction 0.5388492925423278 0.5288070802665205 0.5969392856439804 1.0 0.7998049015423171 3 P01889 1 +Regulation of tolerance induction 0.5388492925423278 0.5288070802665205 0.5969392856439804 1.0 0.7998049015423171 3 P01889 1 +Positive regulation of reactive oxygen species biosynthetic process 0.5404806595458136 0.5270167247014772 0.5981819742989425 1.0 0.8011473211832285 4 P51790,P00403 2 +Regulation of t circle formation 0.4745715088507989 0.5252821210840987 0.5993870843287032 1.0 0.8021318347425717 2 Q15554 1 +Skeletal muscle cell differentiation 0.4438447051778511 0.5252647035026881 0.5993991907099638 1.0 0.8021318347425717 8 P50402 1 +Learning 0.3550156508786778 0.5245937725249692 0.5998656167885863 1.0 0.8021969425273463 24 O00264,Q13641,Q9Y639,P50897,P05067,Q96SB3,P04035 7 +Regulation of stress granule assembly 0.5363781319032781 0.5201938865340413 0.6029284458959474 1.0 0.8045896946937097 3 Q9UN86 1 +Cellular ketone metabolic process 0.3238483027772861 0.5200066034106751 0.6030589726234765 1.0 0.8046025386546184 38 P49748,O14874,Q92604,Q8N0U8,Q06136,Q12770,Q14849 7 +Vesicle mediated cholesterol transport 0.4723236864287644 0.5165320064950125 0.6054828905768241 1.0 0.8060625779899232 2 Q9NVJ2 1 +Autophagosome lysosome fusion 0.4723236864287644 0.5165320064950125 0.6054828905768241 1.0 0.8060625779899232 2 Q9NVJ2 1 +L methionine salvage from methylthioadenosine 0.5373569648694315 0.5160750830572233 0.6058019699244426 1.0 0.8060625779899232 4 Q13126 1 +Amino acid salvage 0.5373569648694315 0.5160750830572233 0.6058019699244426 1.0 0.8060625779899232 4 Q13126 1 +Positive regulation of protein localization to membrane 0.3293966749109457 0.51435878394946 0.6070011698479432 1.0 0.8067890523942605 33 Q9Y3D6,Q12959,O00264,P43378,Q12846,O15258,P27105,Q96SB3 8 +Positive regulation of chemotaxis 0.3681532684132329 0.5137617009118176 0.6074186077790582 1.0 0.8070215282031608 19 Q4KMQ2,O00255,P09429,Q13641,Q12846 5 +Negative regulation of intracellular estrogen receptor signaling pathway 0.4406302813315241 0.5110366478543245 0.6093253952255713 1.0 0.8087476077435535 8 Q9P253 1 +Regulation of receptor signaling pathway via stat 0.4715941006155835 0.5104737996016577 0.609719565603325 1.0 0.8089804139949034 7 Q9NX40 1 +Pyrimidine nucleotide metabolic process 0.3652604772097856 0.5099936207736939 0.6100559309846423 1.0 0.8089804139949034 20 Q9H773,Q9UIJ7 2 +Positive regulation of protein localization to cell surface 0.5173146949380496 0.5093969039003694 0.6104740460865405 1.0 0.8093037403796668 5 Q92544,Q12846 2 +Regulation of erad pathway 0.4707156628957313 0.5068958041056222 0.6122279298958799 1.0 0.8107722384377063 7 P46379,Q9UMX0 2 +Fatty acid derivative metabolic process 0.3552517943204855 0.5011093879032517 0.6162941401934618 1.0 0.813887239097163 23 Q9UMR5,Q53GQ0,Q6Y1H2,P50897,Q9UKU0 5 +Regulation of lipid localization 0.3497250494267097 0.5002899959650952 0.616870897209632 1.0 0.8143772705673678 25 Q8WTV0,P22466 2 +Oogenesis 0.3712562401391819 0.499672126484713 0.6173059621651595 1.0 0.8147899996448109 18 Q8N2A8 1 +Mating 0.4665298561907366 0.4899309402238196 0.6241827680678205 1.0 0.8194784615291665 7 Q96SB3,P00813 2 +Regulation of phagocytosis 0.3790010684138009 0.4895331260506465 0.6244643081724068 1.0 0.8196863847904078 16 Q08722,Q4KMQ2,Q8WTV0 3 +Myoblast fusion 0.4662184789470319 0.4886746345488642 0.6250720645473178 1.0 0.8203223406748965 7 P41440,O75955,Q9H4M9 3 +Mitochondrial protein processing 0.4973112131199484 0.4882954876800279 0.625340557176588 1.0 0.8203397905036725 6 Q99797,Q10713,Q96TA2 3 +Urogenital system development 0.3233121756133495 0.4881336732809583 0.6254551610842425 1.0 0.8203397905036725 49 Q9NZJ7,P07602,O75844,O76024,P46379,O95470 6 +Dna integration 0.4644563079516748 0.4863468371987003 0.6267212765399695 1.0 0.8213529136221932 2 O75531 1 +Dna methylation or demethylation 0.3560017553190522 0.484419232437123 0.6280883719626555 1.0 0.8215267522428208 22 Q8N2A8 1 +Sodium ion homeostasis 0.4644415713260369 0.4815208115002931 0.630146392140728 1.0 0.82255017255345 7 P05023,P54709,P05026,P55011 4 +Negative regulation of adenylate cyclase activity 0.4630514189378875 0.4810310795540896 0.6304944099187222 1.0 0.82255017255345 2 P04899 1 +Amyloid beta clearance 0.4110127196306387 0.4785687426602152 0.632245459434394 1.0 0.8235900461059315 10 Q16850,P04035,P14735 3 +Cellular sodium ion homeostasis 0.5082122265076832 0.4766295097957357 0.633625966027016 1.0 0.8239118413266494 5 P05023,P05026,P55011 3 +Regulation of bone mineralization 0.4628978140760219 0.4753272283683289 0.634553754565008 1.0 0.8244193934218738 7 O75844 1 +Lipid droplet formation 0.5249859262054243 0.473461034287974 0.6358842943918961 1.0 0.8253969142145637 4 Q9Y679,Q14534 2 +Regulation of hydrogen peroxide metabolic process 0.5244913266839533 0.4717822463018107 0.6370822243651781 1.0 0.8263071921945547 4 P00403 1 +Ribose phosphate biosynthetic process 0.2970490595065939 0.4709198841293657 0.6376979478940297 1.0 0.8267835268331906 87 Q13232,Q9UMR5,Q8TB61,Q9UIJ7,O95563,Q9NRA0,Q53GQ0,Q8WVC6,Q6Y1H2,P50897,Q9NZ01,O75964,Q9UKU0,P00813,P00403 15 +Protein hydroxylation 0.3654309252417944 0.4637049003025472 0.6428591858604105 1.0 0.8310465971058726 18 P07237,Q96AY3,Q96HE7,Q92791,Q32P28,Q13162,Q12797,O75718,Q8N543,P13674 10 +Superoxide metabolic process 0.4594800869480983 0.4616883180274503 0.6443048496319548 1.0 0.8321072723269278 7 P00374 1 +Regulation of heart contraction 0.3423271752356123 0.4609752577446435 0.6448163565377558 1.0 0.8322833306359125 26 P05023,P16615,Q12959,P09493,O75844,P10253,Q6PI78,P20020,O95319,P00813 10 +Terminal button organization 0.4574318628828176 0.4600030759648892 0.6455140126343888 1.0 0.8330222521004184 2 O95295 1 +Biomineralization 0.3737927409085224 0.4594152137976362 0.645936025119024 1.0 0.8332436997804041 16 O75844,Q6P4Q7 2 +Chromosome organization involved in meiotic cell cycle 0.3591817258457724 0.456478978534132 0.648045583927642 1.0 0.8346832661664823 19 Q92791,Q9BTX1,P46379 3 +Antigen processing and presentation of exogenous antigen 0.4275369690294563 0.4540126724659826 0.6498197057949824 1.0 0.8360148174970649 8 P04439,Q9UIQ6,Q99538,Q03518 4 +Positive regulation of lymphocyte chemotaxis 0.4557459960663083 0.4537697287049843 0.6499945735521189 1.0 0.8360148174970649 2 O95747 1 +Regulation of lymphocyte chemotaxis 0.4557459960663083 0.4537697287049843 0.6499945735521189 1.0 0.8360148174970649 2 O95747 1 +Regulation of t cell chemotaxis 0.4557459960663083 0.4537697287049843 0.6499945735521189 1.0 0.8360148174970649 2 O95747 1 +Response to retinoic acid 0.3932484794513622 0.4512524510476562 0.6518076105109736 1.0 0.8370076918322682 12 Q8TB36,Q9P0J0 2 +Magnesium ion homeostasis 0.5160413490267192 0.4512164805195865 0.6518335327775877 1.0 0.8370076918322682 3 Q6P4Q7 1 +Negative regulation of extrinsic apoptotic signaling pathway 0.3339570248330439 0.4511625389358151 0.6518724067267687 1.0 0.8370076918322682 29 P09601,Q8IWB1,P02545 3 +Regulation of cardiac muscle cell action potential 0.4869704481267686 0.4501450096365725 0.6526058842200191 1.0 0.8377449929440361 6 P16615 1 +Secretory granule localization 0.5154581225407591 0.4492915630851327 0.6532213431838167 1.0 0.8382545389294833 3 P33176,Q12756 2 +Regulation of leukocyte apoptotic process 0.3861897725529294 0.4484673242225943 0.6538159632259464 1.0 0.8385325178779482 13 Q9HCL2,P00813 2 +Golgi vesicle transport 0.2884742023148327 0.4434144821639752 0.6574659626850523 1.0 0.8409448359925087 142 Q9Y3A6,Q9NR31,O60499,O15126,Q12893,O15260,P61026,Q9H4A6,Q969M3,Q96RL7,Q5BJH7,P24390,P11279,Q9NZ43,P49257,Q9Y282,P49755,Q9Y6B6,Q9BZG1,Q8NHH9,Q12770,Q9UEU0,Q9BVK6,O15127,P51572,Q9P2W9,Q8TBA6,Q969X5,Q15363,Q9BSR8,Q12981,O95070,O15258,O60826,O14828,Q96PC5 36 +Bile acid metabolic process 0.3972248757221931 0.4406509728493508 0.6594656949180684 1.0 0.8426737979386504 11 Q96SU4,O15118,Q9BXW6 3 +Pyrimidine containing compound metabolic process 0.3299041736606872 0.4404966576382745 0.6595774325262855 1.0 0.8426737979386504 30 Q9HC21,Q9H773,Q9UIJ7 3 +Negative regulation of epithelial cell apoptotic process 0.4539481588609692 0.4398335893330989 0.6600576379478262 1.0 0.8431254473210716 7 P09601 1 +Protein maturation by protein folding 0.4839139001720881 0.4390382540036426 0.6606338181629516 1.0 0.8435376170135156 6 O76024,Q13162,O00170 3 +Regulation of cell aging 0.3774057276263062 0.4381125855161641 0.661304671530452 1.0 0.8437466620082742 14 O75844 1 +Leukocyte differentiation 0.3051864304390306 0.43689039076226 0.6621908411009174 1.0 0.844505663996923 78 O00625,P05141,P24390,O96005,P0CG08,P01889,P04062,Q8N5M9,Q6IAN0,Q14739,P12956,P00813 12 +Cellular carbohydrate catabolic process 0.3557160750840421 0.4345912391299474 0.6638591552740392 1.0 0.8458570489294701 19 Q9NUJ1,Q14108,P10253 3 +Positive regulation of cell cycle checkpoint 0.4825992575060412 0.4342860677204757 0.6640807197842182 1.0 0.8458570489294701 6 Q5JVF3,P12270 2 +Fibroblast migration 0.3692706805155352 0.4335105014713209 0.6646439385774532 1.0 0.8458989120736184 16 O95470 1 +Positive regulation of receptor mediated endocytosis 0.3955382626577644 0.4325236123515917 0.6653608945409655 1.0 0.84648762247565 11 P50897 1 +Membrane invagination 0.3818428323518902 0.4259843701705356 0.6701192350919263 1.0 0.8494559065784323 13 Q4KMQ2,P51809,Q14185,Q96GD4,P51790 5 +External encapsulating structure organization 0.3351587094603524 0.4236122356606164 0.6718486304493485 1.0 0.8506759200229099 27 P41440,O75955,Q92791,Q53GQ0,P50454,Q13162,P05067 7 +Ameboidal type cell migration 0.3029933311291537 0.4230357599484133 0.6722691707192383 1.0 0.8509700203496199 79 P09601,P36896,Q9NQC3,P42785,Q8WTV0,O95470 6 +Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.3810597519729447 0.421957555553644 0.6730559983735227 1.0 0.8515565910980596 13 Q9BYG3,P42766,Q9H7B2,Q6DKI1,Q9NVP1,Q9GZL7,O60287,Q14137,Q9BZE4,O00541,P18124,Q8IY81 12 +Macroautophagy 0.2872286668646031 0.4207502010336924 0.6739374992092586 1.0 0.8516340657840761 120 Q9UMX0,P13473,Q93050,P21796,O15118,P12235,P05141,O95140,P53365,Q96HY6,Q86Y82,P09601,Q9UEU0,P16615,Q6PHR2,P04062,P46934,Q8NHS3,O14681,P27544,Q99623,O15269 22 +Amine metabolic process 0.3579466238864949 0.4180584229807884 0.6759044024984817 1.0 0.8528710882640502 18 Q96QD8,P21964,O14874 3 +Glycoside catabolic process 0.4778190465460677 0.4171362084118587 0.67657878184195 1.0 0.8529327132332217 6 Q9NUJ1,P04062,P08236 3 +Protein maturation 0.3052804196628902 0.4150821540470024 0.6780817631219427 1.0 0.8545037177762789 76 Q92542,Q99797,Q10713,Q15005,Q9UJZ1,P35670,Q8TCT9,O76024,Q13162,P61009,Q86UY6,P67812,Q9UG56,O75503,Q15392,Q9BU23,Q96TA2,P42892,O75844,P50454 20 +Extrinsic apoptotic signaling pathway via death domain receptors 0.3525734445512007 0.4148716969471772 0.6782358301188292 1.0 0.8545324880073508 19 P09601,Q8IWB1 2 +Cellular response to xenobiotic stimulus 0.3263974146813459 0.4126713759605494 0.6798473992027971 1.0 0.8551095145897969 30 P07099,P27544,P16435,O43169 4 +Regulation of gtp binding 0.4761294453428261 0.4111242305769287 0.6809814434342165 1.0 0.8557972320540169 6 O75503 1 +Positive regulation of neutrophil migration 0.4890326209223952 0.4098287139202125 0.6819316011423289 1.0 0.8557972320540169 5 Q8NE86,P63000,Q07021,Q8NHP6 4 +Positive regulation of granulocyte chemotaxis 0.4890326209223952 0.4098287139202125 0.6819316011423289 1.0 0.8557972320540169 5 Q8NE86,P63000,Q07021,Q8NHP6 4 +Response to reactive oxygen species 0.3109863781946375 0.4089616625114992 0.6825677958630754 1.0 0.856358479003925 37 P09601,Q99720 2 +Positive regulation of syncytium formation by plasma membrane fusion 0.4754365024479724 0.4086662556074886 0.6827846007822711 1.0 0.856358479003925 6 P41440,O75955,Q9H4M9 3 +Regulation of syncytium formation by plasma membrane fusion 0.4754365024479724 0.4086662556074886 0.6827846007822711 1.0 0.856358479003925 6 P41440,O75955,Q9H4M9 3 +Activation of innate immune response 0.3509099428494516 0.4044854394595535 0.6858557829479324 1.0 0.8586099013390689 19 Q7Z434,P09429,Q8WXF1,P23246,Q13177,P12956,P43243 7 +Leukocyte apoptotic process 0.3440516030808279 0.4036467475093445 0.6864725043557423 1.0 0.8588529029614409 22 P24390,P00813 2 +Response to vitamin 0.3704252691098815 0.4009525270851705 0.6884550759555976 1.0 0.8599101342068896 14 P30536,Q8TB36 2 +Positive regulation of endothelial cell development 0.4408541725203711 0.4003011158302166 0.6889347462006148 1.0 0.8601289733962395 2 P35611 1 +Regulation of lysosomal protein catabolic process 0.5026489675977824 0.3997381760348902 0.6893493707724629 1.0 0.8602325262499045 4 P04062 1 +Regulation of protein catabolic process in the vacuole 0.5026489675977824 0.3997381760348902 0.6893493707724629 1.0 0.8602325262499045 4 P04062 1 +Negative regulation of lymphocyte activation 0.3591280144615066 0.3987519516964873 0.6900759838771384 1.0 0.8606551110761538 17 P22466 1 +Regulation of epithelial cell apoptotic process 0.3881530071227282 0.3973181076927046 0.6911328960210801 1.0 0.8618117712235878 11 P09601,Q4KMQ2,O76024 3 +Positive regulation of hormone secretion 0.3475594828904185 0.3955190854866843 0.6924598392597501 1.0 0.862658223563017 20 P22466,Q12846 2 +Lipoprotein catabolic process 0.4841828998864446 0.3934652031821459 0.6939759196022997 1.0 0.8628719539324219 5 Q9NUJ1,P50897 2 +Cellular response to retinoic acid 0.3976666704729372 0.393173156792256 0.69419159431542 1.0 0.8628719539324219 9 Q9P0J0 1 +Ubiquinone metabolic process 0.5003477983485954 0.3924014589205021 0.6947616082501111 1.0 0.8629794218391427 4 Q8NI60 1 +Regulation of reproductive process 0.3488822786366702 0.3918762417785979 0.6951496581655396 1.0 0.8629794218391427 19 P36896,Q8IXJ6 2 +Maintenance of blood brain barrier 0.441474395047843 0.3916317652388664 0.6953303137549938 1.0 0.8630032148525706 7 P11047,P55011,Q07157,Q9UDY2,P18206,P05556 6 +Cellular response to dsrna 0.3972413665614448 0.3913061333253828 0.6955709658540603 1.0 0.8631409244375855 9 P41440,O75955,P06748,Q7Z434 4 +Negative regulation of neuron projection development 0.3359166017795886 0.3886609656300638 0.6975269613714796 1.0 0.864519262651803 24 Q9NR77,Q96G23,Q9NQC3 3 +Response to catecholamine 0.3464378409863188 0.3883987682351678 0.6977209556277737 1.0 0.864519262651803 20 Q92542,P0DMN0,Q8IXJ6 3 +Neural retina development 0.4115631025327324 0.3867402668288918 0.6989485026801496 1.0 0.8657579114020482 8 P54802,Q8NBN7,P20020 3 +Regulation of long term synaptic potentiation 0.4111310827219211 0.3849598684002696 0.7002671488391674 1.0 0.8664011008807374 8 Q92542,P05067,Q9Y639 3 +Dendritic transport 0.4389088064937166 0.381915318932244 0.7025241771832589 1.0 0.8675632583326383 7 Q14254,P23246 2 +Regulation of monocyte chemotaxis 0.4801610968754353 0.380068815738413 0.7038943333630656 1.0 0.8681468702237364 5 Q4KMQ2,P09429 2 +T cell differentiation 0.3165756907265599 0.3794462323243753 0.704356524426506 1.0 0.8683758188326042 32 P24390,O96005,P04062 3 +Histone h3 k9 modification 0.3630646855136173 0.3787175296195701 0.7048976346122748 1.0 0.868405707885492 15 Q9NRA0 1 +Regulation of peptidyl threonine phosphorylation 0.3942870925547569 0.3783973722187527 0.7051354199975437 1.0 0.868405707885492 9 Q8IXJ6 1 +Negative regulation of response to endoplasmic reticulum stress 0.3724587934834282 0.3782303264868644 0.7052594986403338 1.0 0.868405707885492 13 O95881,O76024,O60313 3 +Endocytosis 0.2847895411986348 0.3781836204011162 0.7052941925050464 1.0 0.868405707885492 136 Q14108,Q9UL25,Q13432,P30533,O15260,O15118,Q8WTV0,P27824,P50897,Q9UBC2,Q9NX40,Q4KMQ2,O75955,Q5VW38,P46934,P41440,Q9H223,O14656,P51790,P05067 20 +3 phosphoadenosine 5 phosphosulfate metabolic process 0.4792342240919627 0.3770043266940078 0.7061703895284404 1.0 0.8686809505197357 5 Q8TB61 1 +Regeneration 0.3073034411131656 0.3761760298607576 0.7067860342990093 1.0 0.8686816029547859 37 P09601,P30536,Q96G23 3 +Neuromuscular process controlling balance 0.3715920194719775 0.3738770659232853 0.7084957798549985 1.0 0.8694681331077391 13 P05067,P10253,P17900,O14773 4 +Vesicle targeting rough er to cis golgi 0.3881020059309282 0.3725925445190385 0.7094517225398449 1.0 0.8698233628413169 10 P49755,Q15363,Q9NR31 3 +Calcium mediated signaling using intracellular calcium source 0.4910229432636221 0.3716177510701788 0.710177470718987 1.0 0.8700269111807583 3 P51572 1 +Cell junction maintenance 0.3924385015795278 0.3703743842678978 0.7111035572654902 1.0 0.8705655212659745 9 Q12959 1 +Regulation of apoptotic signaling pathway 0.2821324262778057 0.370067003377014 0.7113325670267834 1.0 0.8706857152038336 106 P07237,P09601,P05141,Q9UMX0,Q9H3K2,O95881,Q9P0J0,P51572,P45880,Q07820,O76024,P23246,Q9UL15,P02545,Q12846,Q8IWB1,P04179,O60313 18 +Utp metabolic process 0.4632266092344896 0.3661180519447997 0.7142769877950188 1.0 0.8728061908163219 6 Q9UIJ7 1 +Neurotransmitter uptake 0.4345619895702058 0.365616226530003 0.7146514652258706 1.0 0.8728217106034445 7 P41440,O75955 2 +Transition metal ion homeostasis 0.3227913760182292 0.3647519588679907 0.7152965691486632 1.0 0.8734492968228172 29 P09601,Q8N511,P30519 3 +Regulation of oxidative stress induced cell death 0.3440142012512575 0.3618434316383497 0.7174690343932149 1.0 0.8752990694568001 19 Q9UMX0,Q07820,P23246,Q9UL15,P04179 5 +Positive regulation of transport 0.2807961906148685 0.3613235690084794 0.7178575766477062 1.0 0.8756125682900449 198 Q9UL25,Q15041,Q9NR31,Q9NRA0,O76024,Q12846,Q9H4A6,P50402,P11279,P22466,Q92544,Q12959,Q9Y282,Q08722,P55786,P50897,P08183,Q4KMQ2,O75955,Q5T9L3,O95563,P46934,P51572,Q9P2W9,P41440,P27105,P30536 27 +Phospholipid dephosphorylation 0.4315484367560248 0.354440517378752 0.7230087743551499 1.0 0.8801213450399712 7 Q10713 1 +Maintenance of synapse structure 0.459577198491684 0.3536935199300847 0.7235685794453097 1.0 0.8803197250838275 6 Q12959 1 +Lens development in camera type eye 0.4028758093919298 0.3513684597329554 0.725311941267105 1.0 0.8814738804113557 8 P08670,Q12959 2 +Positive regulation of insulin secretion involved in cellular response to glucose stimulus 0.4584236187468048 0.3497953954480389 0.7264922549119823 1.0 0.8824173980079767 6 Q12846 1 +Regulation of endocytosis 0.3094698728788793 0.3496269485129754 0.7266186838593107 1.0 0.8824173980079767 55 Q4KMQ2,P41440,O75955,Q9UL25,Q9H223,Q13432,O14656,P50897,P05067 9 +Positive regulation of vesicle fusion 0.4855215068878197 0.3463979896502543 0.7290436357322418 1.0 0.8849371080343381 4 P04083,Q86YS7,P07355 3 +Organelle disassembly 0.3091727207504995 0.3463330461837366 0.7290924362663074 1.0 0.8849371080343381 53 P05141,P21796,P04062,O95140,P52789,Q96HY6,P27544,Q99623,P30536,P12235 10 +Regulation of animal organ morphogenesis 0.3768706409691439 0.3448442195993861 0.7302114873694279 1.0 0.8858866633075024 11 Q8TAA9 1 +Chromatin disassembly 0.3594679482035479 0.343925074233381 0.7309026343527099 1.0 0.8862275188445791 14 Q66K74,Q969G3,Q01105 3 +Collagen fibril organization 0.3816438176466891 0.3438559801092958 0.7309545981875123 1.0 0.8862275188445791 10 Q96AY3,Q92791,P50454,O75718,P13674 5 +Syncytium formation 0.400294405143336 0.3410383270120209 0.7330747286639929 1.0 0.8879492763699596 8 P41440,O75955,Q9H4M9 3 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.3487761882548127 0.3393452156214737 0.7343496840885371 1.0 0.8890480530487929 17 O95881,O76024,P46379 3 +Extrinsic apoptotic signaling pathway 0.3083898755147285 0.3390628750096092 0.7345623650347894 1.0 0.8891437867054427 52 P09601,P36896,Q9P0J0,Q07820,P02545,Q8IWB1 6 +Cellular response to gamma radiation 0.3698489927337027 0.3370253333667504 0.7360978028931187 1.0 0.8899030702792754 12 O75844 1 +Mononuclear cell migration 0.3234271102087172 0.3370144566124648 0.736106002164711 1.0 0.8899030702792754 27 Q4KMQ2,P04062,P09429,Q08722,P05067 5 +Regulation of heart rate 0.3798880122065251 0.336140482328295 0.7367649322091361 1.0 0.8903523922011622 10 P00813,P16615 2 +Tissue migration 0.3079780711187079 0.3347188887588558 0.737837151399138 1.0 0.8911309457427007 55 P09601,Q8WTV0,P42785 3 +Chaperone mediated autophagy 0.3840632328896255 0.3345762014961435 0.7379447996976745 1.0 0.8911309457427007 9 P10619 1 +Phosphatidylinositol dephosphorylation 0.45074786818869 0.3242272040342496 0.7457660277294891 1.0 0.8971570705964841 6 Q10713 1 +Hormone transport 0.3027222737717349 0.3239125798229441 0.7460042196989476 1.0 0.8972814173317362 39 P22466,O95563,Q8N5M9,Q12846,P40939 5 +Regulation of biomineralization 0.375828425110783 0.3184678188983168 0.7501301017008559 1.0 0.9007787489749542 10 O75844 1 +Chemokine c c motif ligand 5 production 0.4152851924697925 0.3158593759145052 0.7521092478304465 1.0 0.90250397481277 2 Q7Z434 1 +Positive regulation of chemokine c c motif ligand 5 production 0.4152851924697925 0.3158593759145052 0.7521092478304465 1.0 0.90250397481277 2 Q7Z434 1 +Intrinsic apoptotic signaling pathway in response to dna damage 0.3253137637426904 0.3154425126909964 0.7524256927030841 1.0 0.9027209275174012 24 Q07820,P09601 2 +Positive regulation of cold induced thermogenesis 0.35945678767197 0.3140588861110928 0.7534763149268153 1.0 0.9031554666839828 13 P40939,O00767,P23786 3 +Positive regulation of low density lipoprotein receptor activity 0.4713322091062473 0.3136779112186976 0.7537656789322074 1.0 0.9031554666839828 3 Q9Y2B0,P07355 2 +Positive regulation of atp biosynthetic process 0.4742023741451043 0.3128442428956991 0.7543990003099439 1.0 0.9032441632533386 4 P00403 1 +Positive regulation of nucleotide biosynthetic process 0.4742023741451043 0.3128442428956991 0.7543990003099439 1.0 0.9032441632533386 4 P00403 1 +Golgi organization 0.3048686013816346 0.312723810736489 0.75449050391064 1.0 0.9032441632533386 61 Q9BSR8,Q9BTU6,Q9UEU0,Q9BVK6,P49257,O15260,P49755,Q7RTS9,Q8TBA6,Q9P2W9,Q9UL15,P48729,Q15363,Q8NHH9,Q9H4A6,Q9Y3A6 16 +Positive regulation of leukocyte chemotaxis 0.3587936865839729 0.3108546007725864 0.7559111590399863 1.0 0.9041316972342036 13 Q4KMQ2,P28482,P63000,Q07021,Q8NE86,P09429,Q99538,Q9H4A3,Q8NHP6,P27361,O00429,O95747 12 +Response to steroid hormone 0.2935339958856264 0.3101998216387642 0.7564090061566611 1.0 0.9042582660349806 79 P05023,Q9P253,P04062,P46934,O15118,Q99623,Q96HY6,O15173,P16278,P30536,P16435 11 +Positive regulation of muscle cell differentiation 0.3782086398067993 0.3101190047958966 0.7564704605059651 1.0 0.9042582660349806 9 P04179,Q9BWF3,Q16539,Q15014 4 +Folic acid containing compound metabolic process 0.3500960322889194 0.3100006203087505 0.7565604846405367 1.0 0.9042582660349806 15 Q9H2D1 1 +Inositol lipid mediated signaling 0.3319075835225642 0.309466314322131 0.7569668326301326 1.0 0.9042671705868788 21 Q8IXJ6,P46934 2 +Receptor metabolic process 0.3003868661587361 0.3090206042666051 0.7573058534503982 1.0 0.9042671705868788 38 P49354,O75955,P46934 3 +Pteridine containing compound metabolic process 0.3391915442937306 0.3070570645042183 0.7587999375636194 1.0 0.9053089968601448 18 Q9H2D1 1 +Regulation of immune effector process 0.3044926735353769 0.3051858855763014 0.7602245816397062 1.0 0.9066836184251336 49 P09601,P11279,O15400,Q9NRA0,Q08722,Q99623,Q12846 7 +Fibroblast proliferation 0.342057000510326 0.3016778949246585 0.762897620928513 1.0 0.9084064532616306 17 P50402,O75844 2 +Positive regulation of smoothened signaling pathway 0.4160125523866752 0.2985463670408873 0.7652861928314574 1.0 0.9102327888693208 7 P16435,Q6PHR2 2 +Organophosphate metabolic process 0.2858326452537327 0.2983980899519064 0.7653993466995599 1.0 0.9102327888693208 275 Q13232,Q10713,Q9UKK9,Q9NRA0,Q8WVC6,O75964,Q9H490,P37268,Q9UKU0,Q8WTV0,Q5H8A4,P04035,Q9UMR5,Q12959,Q9UG56,Q9H773,Q8NCC3,Q53GQ0,P50897,Q9NZ01,Q8NF37,Q9BRR6,Q9BTU6,Q9HCL2,Q9NUQ2,P56385,P0DMN0,O95563,Q6IAN0,Q92604,O75947,P43490,Q6Y1H2,Q8NHP8,O43292,O14735,Q86YN1,P24539,Q9UJS0,P00403,Q8TB61,Q9UIJ7,Q9NTJ5,P52789,Q9NPH0,Q99623,Q969T7,Q92643,O60313,P06576,P05067,Q96N66,P40939,P00813 54 +Deoxyribose phosphate metabolic process 0.3410934088875778 0.2963390551862355 0.7669711628978884 1.0 0.9113003194225044 17 Q9H773 1 +Regulation of defense response to virus 0.3368167508042977 0.2934058883285113 0.7692119251764444 1.0 0.9123338731151732 18 O75844,O43657 2 +Peptidyl proline modification 0.2977748086964396 0.2924752317351044 0.7699232946014467 1.0 0.9130003446246744 37 P07237,Q9NWM8,Q9Y680,Q13162,Q9BV86,O00170,Q9Y3C6,Q8N543,Q13427,P13674,Q6UX04 11 +Muscle cell proliferation 0.3218775631717517 0.2921433784119718 0.7701770014222982 1.0 0.9130003446246744 24 P09601,P09493,P04179,P12956 4 +Purine containing compound salvage 0.3735784326345969 0.2911283526686428 0.7709531563296081 1.0 0.9130768303409146 9 Q13126 1 +Negative regulation of lyase activity 0.4631815626756687 0.2910360160014478 0.7710237743636583 1.0 0.9130768303409146 3 P04899,Q9NRX4 2 +Retrograde transport endosome to golgi 0.2981778821043186 0.2896373639955363 0.772093679295518 1.0 0.9136542973321142 38 Q8NBN3,Q9UEU0,P49257,O60499,O75503,O15260,P53367 7 +Negative regulation of neuron death 0.3030295114517086 0.2893563320576096 0.7723087082632758 1.0 0.9137270139541512 50 P09601,P04062,O76024,Q01105,P50897 5 +Fat cell differentiation 0.312569606129132 0.2874665121245374 0.7737551397620135 1.0 0.91478778737186 29 Q9BRK5,Q8N4Q0,Q8IXJ6 3 +Regulation of synaptic vesicle endocytosis 0.4615007657504062 0.2864694661575168 0.7745185764289 1.0 0.9152161909203074 3 O14656 1 +Regulation of mitochondrial dna replication 0.461495222034859 0.2864544633759611 0.7745300657044532 1.0 0.9152161909203074 3 P49916,Q9UJZ1 2 +Regulation of dna helicase activity 0.4614952220348564 0.2864544633759542 0.7745300657044585 1.0 0.9152161909203074 3 P33993,P49736 2 +Fatty acid alpha oxidation 0.4646857870967897 0.2857594254082032 0.7750623866087218 1.0 0.9156826172343412 4 O43808 1 +Epithelial structure maintenance 0.4048890137679137 0.2844725034383258 0.7760483030478389 1.0 0.915925868688964 2 P78310 1 +Positive regulation of protein kinase b signaling 0.3475185566876875 0.283816227409078 0.776551218011456 1.0 0.915925868688964 14 Q9NQC3 1 +Intermediate filament based process 0.3530687889572706 0.2834889860274864 0.7768020234043242 1.0 0.915925868688964 13 P08670,P07197,O14656,P48729,P07196 5 +Cardiac conduction 0.3418890450090749 0.2826216656611362 0.7774668703648797 1.0 0.9162461523425314 16 O75844,P16615 2 +Regulation of superoxide anion generation 0.463311779589543 0.2819372769722785 0.7779916055857763 1.0 0.9167022194003792 4 P04899,Q05655,Q9NY61 3 +Cell growth 0.2770840049138571 0.2804104028219397 0.7791626567780008 1.0 0.9171575780522429 116 P36896,Q5BJF2,P51812,Q9P0J0,Q9NRA0,Q9NQC3,O14681,Q9BSK2,P50897 9 +Medium chain fatty acyl coa metabolic process 0.4032031469513871 0.2795538079507736 0.7798198504170448 1.0 0.9175597519249016 2 P51659 1 +Homeostasis of number of cells 0.2994720441384581 0.2794299647659338 0.7799148779733949 1.0 0.9175597519249016 67 Q92542,P09601,Q9HCL2,P36896,P04062,O95067,P00813,Q9P0S9,Q9NX40 9 +Negative regulation of fibroblast proliferation 0.4104762479663489 0.2793708255328145 0.7799602579472831 1.0 0.9175597519249016 7 P50402 1 +Regulation of actin filament based movement 0.4365125047344415 0.2786043602964212 0.7805484661255266 1.0 0.917921537553772 6 P16615 1 +Actin filament based movement 0.3112654029116534 0.2777537453836578 0.7812014003144505 1.0 0.9182082866641944 29 P05023,P16615,Q12959,Q9UM22,Q9UH99 5 +Response to toxic substance 0.3015130011584304 0.2767346657871247 0.781983851529287 1.0 0.9186412236412012 49 Q8TED1,P35670,P07099,Q15165,P27544,P00374,P08183 7 +Cellular macromolecule localization 0.2932599014834492 0.2744110493199381 0.7837687526758159 1.0 0.920088384028498 613 Q9P0I2,Q9GZP9,Q14108,O60830,Q9NS69,Q8WWC4,Q99595,Q8N4V1,Q96GD4,Q8TCT9,Q53H12,Q15629,P56589,P49354,Q86YV9,Q8N766,P24390,P43307,Q8N4H5,Q9Y282,P49257,O95140,P49711,P49755,P53365,Q9Y6B6,Q7Z3B4,P40855,Q9UEU0,Q9BVK6,Q5T9L3,Q9UPT5,Q9HD45,Q92796,Q9P2W9,O60725,Q9BUN8,P35241,Q9NQC3,P43378,Q13641,Q9Y6C9,O14773,Q9HD20,P27105,P30536,Q14141,Q9Y5J9,Q9Y3D6,Q9UGP8,Q99797,Q15041,O60499,Q16181,Q14254,Q9UNK0,O15118,P61026,P61009,Q9NPF5,Q5BJH7,Q9P253,O14925,P55786,Q96A33,Q99805,P35613,O75955,P50748,O00264,P46934,O43292,Q15070,Q15363,Q9P0J0,Q9Y5J6,P02545,Q5W0Z9,Q92643,P10619,Q10713,Q15005,Q9Y5M8,P13473,Q969Q5,Q12846,P46379,Q9H490,Q9H4A6,Q96RL7,P50402,P11279,Q12959,O96008,Q8TB36,O15400,Q9UH99,Q99623,O15258,Q5JTV8,Q9UL25,Q9NPA0,Q9NR31,O43615,O15260,Q9Y512,Q9UNL2,Q5J8M3,O75915,Q92544,O43681,P53367,Q96HY6,Q86Y82,Q96SB3,O94901,O75381,P51572,O15504,P41440,Q9H223,P52789,O14656,Q9Y3A6,Q9UBV2 125 +Odontogenesis 0.3562144171041184 0.2740203193292485 0.7840690065251326 1.0 0.920108218520592 12 P35613 1 +Endoplasmic reticulum plasma membrane tethering 0.4567172568858979 0.2736694186055879 0.7843386812422717 1.0 0.920108218520592 3 O95292,A0FGR8 2 +Endoplasmic reticulum localization 0.4567172568858979 0.2736694186055879 0.7843386812422717 1.0 0.920108218520592 3 O95292,A0FGR8 2 +Prostanoid metabolic process 0.3509125989970261 0.2733256189837288 0.7846029237283549 1.0 0.9201169093550003 13 Q9H7Z7,Q8N4Q0 2 +Glycoside metabolic process 0.3691010980753701 0.2730745461365744 0.7847959126192463 1.0 0.9201579983229536 9 Q9NUJ1,P04062,P08236 3 +Positive regulation of potassium ion import across plasma membrane 0.4558740865654945 0.2714436325197092 0.7860498473572812 1.0 0.9205385048069352 3 P54709,P05026 2 +Regulation of immune response 0.2778822180576893 0.2713931061455038 0.7860887036540665 1.0 0.9205385048069352 134 P09601,O43657,Q9NPR9,O75955,P11279,P51812,Q8TCT8,Q9UMX0,O15400,Q9NRA0,Q9NQC3,Q9H078,Q08722,Q99623,Q12846,P46379,P12956,P00813 18 +Pyrimidine ribonucleotide metabolic process 0.3601499704630071 0.2704222189397707 0.7868354484056299 1.0 0.9209268218676516 11 Q9UIJ7 1 +Regulation of endoplasmic reticulum tubular network organization 0.4445002641928481 0.268937166756613 0.7879780353095467 1.0 0.9212919580086144 5 Q15041 1 +Cardiac cell development 0.3357096464481459 0.2668194300833558 0.7896081933931911 1.0 0.9220639633324595 17 O75844 1 +Protein hexamerization 0.4061983906608783 0.2648387479909056 0.7911336857573192 1.0 0.923521255694608 7 Q96TA2,O95202 2 +Lung alveolus development 0.4523704415275002 0.2622936960277778 0.7930950217835244 1.0 0.9244623116650104 3 P00813 1 +Lymphocyte chemotaxis 0.4560022490863128 0.2619902423769673 0.79332896497654 1.0 0.9244623116650104 4 Q15149,P55011,O95747 3 +T cell chemotaxis 0.4560022490863128 0.2619902423769673 0.79332896497654 1.0 0.9244623116650104 4 Q15149,P55011,O95747 3 +Aminophospholipid translocation 0.3967406574880535 0.2611530007450354 0.7939745206663398 1.0 0.9245523452728048 2 Q9NV96 1 +Immune response to tumor cell 0.4517960754381278 0.2608090263081184 0.7942397833094854 1.0 0.9245523452728048 3 P09429 1 +T cell mediated immune response to tumor cell 0.4517960754381278 0.2608090263081184 0.7942397833094854 1.0 0.9245523452728048 3 P09429 1 +Inner ear receptor cell development 0.3783628152616728 0.2569723596981286 0.7972001104982185 1.0 0.9258929730132014 8 Q9Y6M7 1 +Regulation of tube size 0.3473389675906443 0.2566615007623593 0.7974400940537347 1.0 0.9260100900240106 13 Q9HB40 1 +Cytosolic calcium ion transport 0.3152809316894746 0.2564572539545337 0.7975977833146617 1.0 0.9260316203696918 25 P16615,Q96AQ8,P21796,O95202 4 +Deoxyribonucleoside triphosphate biosynthetic process 0.449971894322661 0.2561225592382599 0.7978562030661205 1.0 0.9261700735051512 3 P04818,P55263 2 +Regulation of extrinsic apoptotic signaling pathway 0.2956426773865723 0.2556753844057235 0.7982015039416885 1.0 0.9263477988301038 40 Q07820,Q8IWB1,P09601,P02545 4 +Protein processing involved in protein targeting to mitochondrion 0.4484411773552534 0.2522240315380796 0.8008679039354583 1.0 0.9286941802910742 3 Q10713 1 +Vesicle targeting to from or within golgi 0.3511960916952377 0.2516037609894167 0.801347351281636 1.0 0.9287599537611222 12 P49755,Q9Y6B6,Q15363,Q9NR31 4 +Mononuclear cell differentiation 0.2995319442011979 0.2510785454408082 0.8017533829656691 1.0 0.9287599537611222 55 P05141,O00625,P24390,O96005,P0CG08,P01889,P04062,P12956,P00813 9 +Organic acid biosynthetic process 0.2810902893233074 0.2510767426814556 0.8017547767284419 1.0 0.9287599537611222 86 P09960,P28288,Q8NCG7,A1L0T0,Q53GQ0,Q9NZ01,P00374,O15121,Q12770,O95864,Q9P035,Q9H7Z7,Q92604,Q9BV57,Q6Y1H2,O00767,P49748,O14880,Q96SU4,Q13126,Q99735,Q9BXW6 22 +Negative regulation of organic acid transport 0.4509801286937948 0.2486703091699277 0.803615817363206 1.0 0.9299362310123692 4 O75915 1 +Calcium ion regulated exocytosis 0.3580831283496598 0.2441730648286102 0.8070967869521959 1.0 0.9328893616152076 10 P16615 1 +Pentose metabolic process 0.4356283235970891 0.2436538631990274 0.8074989083597459 1.0 0.9329696588774496 5 Q9UKK9 1 +Gtp metabolic process 0.344041644265457 0.2414922002247173 0.8091736609503208 1.0 0.9339317921651726 13 Q13232,Q9UIJ7 2 +Demethylation 0.3306362514044984 0.2395079578446331 0.8107117265420118 1.0 0.9348962987588092 17 Q16850 1 +Pericyte cell differentiation 0.3885923012082019 0.2390002494515459 0.8111053893114171 1.0 0.9350262196202116 2 O95747 1 +Cytokine production involved in inflammatory response 0.3982825300208609 0.2386304037278077 0.8113921873350747 1.0 0.9350676901038566 7 Q8IV08 1 +Neuronal stem cell population maintenance 0.4227848101265851 0.2369975068078694 0.8126587244469721 1.0 0.936006197852994 6 P19022,Q86VS8,Q9BXW9,Q15154,Q9NZI8 5 +Developmental pigmentation 0.3974263585265699 0.2358503761150752 0.8135487761099505 1.0 0.9363831035993982 7 P04179 1 +Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4417686543842051 0.2355969364796759 0.8137454508884081 1.0 0.9364114616394152 3 Q07820 1 +Response to ischemia 0.3578265765765696 0.2290476957537178 0.818831845493762 1.0 0.9408366594891204 9 Q9UNE7,O75116,P52789,O95831,Q9NQ88,Q9Y4L1,P04637,Q96RD7 8 +Forebrain radial glial cell differentiation 0.3840966563641493 0.2272893713916391 0.8201987372537769 1.0 0.9415943757847104 2 Q86U44 1 +Regulation of vascular associated smooth muscle contraction 0.3840966563641433 0.2272893713916234 0.8201987372537891 1.0 0.9415943757847104 2 P20020 1 +Meiotic spindle assembly 0.4281852746095492 0.2232407872522836 0.8233481091843764 1.0 0.943094951225822 5 O95067 1 +Kidney morphogenesis 0.3525091488536586 0.2219201700643392 0.8243760285619732 1.0 0.9436908637499648 10 O75844 1 +Protein targeting to peroxisome 0.4270225048737234 0.220119404259376 0.8257781629903502 1.0 0.944592737698662 5 P56589,O75381 2 +Pigment cell differentiation 0.4157944835845243 0.216775989753162 0.8283829244418417 1.0 0.9462895860244313 6 P04179 1 +Substantia nigra development 0.3311713235641609 0.2148985900729951 0.8298463841711055 1.0 0.9467474067716716 15 Q8IXJ6 1 +Regulation of er associated ubiquitin dependent protein catabolic process 0.4368828880454163 0.2130201159335046 0.8313112725153804 1.0 0.9474869872563548 4 Q9UMX0 1 +Autophagosome organization 0.2956016084259313 0.212012683196752 0.8320971394832251 1.0 0.94819904009486 32 P16615,Q9UMX0,P04062,O95140,P53365,Q86Y82 6 +Synaptic vesicle transport 0.3372472652523914 0.210890138879444 0.8329729991210622 1.0 0.9485686702858775 13 Q92572,Q96A57,O14656 3 +Respiratory system development 0.3083026166721774 0.2097602470785713 0.8338548010044757 1.0 0.9494103850615544 25 P09960,P00813 2 +Intermediate filament organization 0.412906400064388 0.2086196221605211 0.8347451913402228 1.0 0.9500990676191522 6 P07197,P08670 2 +Peptidyl threonine modification 0.2876222239692745 0.2055021875472085 0.8371797891561559 1.0 0.9518933020389916 37 Q10472,P36896,Q8IXJ6 3 +Positive regulation of dna dependent dna replication 0.4115705594417582 0.2048869474627922 0.8376604533092291 1.0 0.9521162217240998 6 O95785,Q9UJZ1 2 +Epithelial cell maturation 0.4335113859994335 0.2048849932051607 0.8376619801945311 1.0 0.9521162217240998 4 P04818,Q9UK73,Q86UL3 3 +Reproductive behavior 0.4203403987476062 0.2025436867559346 0.8394917089731768 1.0 0.9537072931404048 5 Q96SB3 1 +Mating behavior 0.4203403987476062 0.2025436867559346 0.8394917089731768 1.0 0.9537072931404048 5 Q96SB3 1 +Natural killer cell activation 0.3868158080775361 0.2023191711219272 0.8396672134844119 1.0 0.9537438651201162 7 P46379 1 +Regulation of endocytic recycling 0.4263631253513298 0.1995473721538881 0.8418345907575504 1.0 0.9553903822461628 3 Q9H4M9,Q07960 2 +Programmed necrotic cell death 0.3276025667179681 0.1977597816930016 0.8432330142138482 1.0 0.9563251038843148 15 Q13510 1 +Error free translesion synthesis 0.3708906996347304 0.1950406086008606 0.8453611569759392 1.0 0.9571778223017656 2 Q9Y2S7 1 +Mitochondrial translational elongation 0.429013213382062 0.1942721806663014 0.8459627672510455 1.0 0.95733016757456 4 Q9H9J2,Q96RP9,P49411 3 +Positive regulation of mrna splicing via spliceosome 0.3219985644677817 0.194238308005851 0.8459892885809146 1.0 0.95733016757456 17 P62995,Q15427,P98179,Q13595,Q9Y2W1 5 +Response to copper ion 0.3603088234737888 0.1933618530800378 0.8466755884497397 1.0 0.9574555719852196 8 P35670 1 +Synaptic vesicle localization 0.3283487614642723 0.1927921515016512 0.8471217503748742 1.0 0.9576554819286346 14 P19022,Q96A57,O14656,Q92572,O60282 5 +Cellular response to osmotic stress 0.3281543681393655 0.1919074290101389 0.8478147180976088 1.0 0.9577672634424692 14 P30536 1 +Primary alcohol metabolic process 0.3180861478280648 0.1896200809720458 0.8496068503559497 1.0 0.9587039691918632 18 Q6NUM9,Q9Y394,P0DMN0,Q8NBN7,P51648 5 +Positive regulation of rna splicing 0.3062651354293879 0.1894667151508371 0.8497270400588874 1.0 0.9587039691918632 24 P62995,Q15427,P98179,Q13595,Q9Y2W1,Q96QD8 6 +Vesicle fusion with golgi apparatus 0.3825935194762994 0.189465167008988 0.8497282533242612 1.0 0.9587039691918632 7 Q9BSR8,Q9UEU0,O75396,Q969M3 4 +Cerebral cortex development 0.2947895432358536 0.187744241465133 0.8510771472118857 1.0 0.9597173940403164 31 Q96QD8,Q9NQC3 2 +Regulation of protein localization to plasma membrane 0.2922756430492511 0.1864177790608274 0.8521171511258552 1.0 0.9600131353082968 32 Q9UEU0,Q12959,O15400,O00264,P43378,Q12846,O15258,Q96SB3 8 +Fermentation 0.4179314221472827 0.181237835321157 0.8561808980305139 1.0 0.9619928881298448 3 Q9NQ88,O75746 2 +Glycolytic fermentation 0.4179314221472827 0.181237835321157 0.8561808980305139 1.0 0.9619928881298448 3 Q9NQ88,O75746 2 +Response to mineralocorticoid 0.4024743661094462 0.180155306661065 0.8570306443948861 1.0 0.962308852440652 6 P07196 1 +Sulfur amino acid biosynthetic process 0.4017828389651532 0.1783247961802498 0.8584679063642191 1.0 0.9629367801877428 6 Q13126 1 +Methionine biosynthetic process 0.4017828389651532 0.1783247961802498 0.8584679063642191 1.0 0.9629367801877428 6 Q13126 1 +Axon development 0.2737104449229025 0.1775178275996159 0.8591016632109971 1.0 0.9631862723090644 89 Q66K74,Q9UQB8,P35613,P41440,O75955,Q9UL25,P42892,Q9NQC3,O00264,P10586,Q96G23,P00374,P30536,O15031,Q92581 15 +Regulation of insulin secretion 0.303321854244685 0.1771629257017584 0.859380415976803 1.0 0.9633108755812066 25 Q8N5M9,O95563,P40939,Q12846 4 +Positive regulation of translation in response to endoplasmic reticulum stress 0.415401911186066 0.1759447501928008 0.8603373481289271 1.0 0.9635980100782314 3 Q13217,Q04637 2 +Positive regulation of translation in response to stress 0.415401911186066 0.1759447501928008 0.8603373481289271 1.0 0.9635980100782314 3 Q13217,Q04637 2 +Histone h3 deacetylation 0.4007137347117518 0.175508842502666 0.8606798233087014 1.0 0.9635980100782314 6 Q8IXJ6 1 +Negative regulation of glucose import 0.4151208544125986 0.1753623574884859 0.8607949165912963 1.0 0.9635980100782314 3 P49840,Q06481 2 +Negative regulation of glucose transmembrane transport 0.4151208544125986 0.1753623574884859 0.8607949165912963 1.0 0.9635980100782314 3 P49840,Q06481 2 +Neutrophil activation involved in immune response 0.4151208544125979 0.1753623574884842 0.8607949165912976 1.0 0.9635980100782314 3 P11274,P51809 2 +Neutrophil degranulation 0.4151208544125979 0.1753623574884842 0.8607949165912976 1.0 0.9635980100782314 3 P11274,P51809 2 +Regulation of telomerase activity 0.3054462633054397 0.1703143531145317 0.8647629240156944 1.0 0.9670638983909338 23 Q96GD4,Q96T60,P27544,P22626 4 +Cellular extravasation 0.3415420618994331 0.1694189976865132 0.8654670815045704 1.0 0.9675261930812894 9 Q9H4A6 1 +Regulation of peptide transport 0.3006541394216502 0.1674414031415536 0.8670227499981857 1.0 0.9691025195226616 26 Q8N5M9,O95563,P40939,Q12846 4 +Protein kinase b signaling 0.2992682572645917 0.167187378545658 0.8672226151081079 1.0 0.9691631408135112 27 Q86UE4,Q9NQC3,Q8IXJ6 3 +Negative regulation of histone modification 0.3067506552368874 0.1668300900451272 0.8675037420347762 1.0 0.9693145405039348 22 Q9NRA0 1 +Semaphorin plexin signaling pathway 0.3736793358980185 0.1632818319027065 0.8702965379687089 1.0 0.9716194363666764 7 P42892 1 +Cellular response to lipid 0.2681892357337541 0.1614670617428441 0.871725551844829 1.0 0.9727252762453618 113 P05023,Q9P253,P08670,Q9P0J0,Q9NRA0,P46934,O15118,Q8TB36,Q99623,O15173,Q96HY6,Q86UE4,P30536,Q8WTV0 14 +Regulation of synaptic vesicle exocytosis 0.3290306625522741 0.1583069663709312 0.8742149189944559 1.0 0.9740933440452054 12 Q9P253 1 +Vascular associated smooth muscle cell apoptotic process 0.412624828399284 0.1579876498128607 0.8744665305151422 1.0 0.9740933440452054 4 P04179 1 +Cardiac muscle cell contraction 0.3323994807546438 0.1576067546558673 0.874766680656816 1.0 0.974158678007214 11 P16615,Q12959 2 +Cellular modified amino acid metabolic process 0.2898685300723152 0.1567591716853811 0.8754346512236548 1.0 0.9747394351503134 57 O75915,P41440,Q9H7Z7,O60725,Q8NCC3,Q9H2D1,Q99735,Q8TB36,P00374,Q9UHG3,P23786,P16435 12 +Positive regulation of biomineralization 0.4013453617269451 0.1560655259158646 0.8759813716827014 1.0 0.9751850164851752 5 Q4KMQ2,P20020 2 +Negative regulation of sister chromatid cohesion 0.4110205229125607 0.1546400047319505 0.8771051301187551 1.0 0.9759462700117564 4 Q7Z5K2,Q14674,P41227 3 +Regulation of system process 0.2871800604022734 0.1536127648531246 0.8779150715097193 1.0 0.9762519585499406 68 P05023,P22466,P16615,Q12959,P42892,P09493,O75844,P04062,P10253,Q9UQB8,P02545,P00813 12 +Positive regulation of chromosome segregation 0.3475324758255055 0.151806393034055 0.8793396396673356 1.0 0.97728879458686 8 Q8IXJ6 1 +Lipid droplet organization 0.3350136715630963 0.1469435611737334 0.8831765682476596 1.0 0.9796995577669956 9 Q9Y679,Q96CS3,Q14534 3 +Suckling behavior 0.4072009201761989 0.1468184343893395 0.883275333824489 1.0 0.9796995577669956 4 P05067 1 +Bile acid biosynthetic process 0.3343767114928481 0.144796785383295 0.8848713203704548 1.0 0.9809401289715662 9 Q96SU4,Q9BXW6 2 +Rrna transport 0.3461646529924183 0.1434824021921506 0.8859092084596389 1.0 0.9813125469871666 2 P06748 1 +Regulation of phosphatidylinositol 3 kinase signaling 0.3248741684503635 0.14195176322185 0.8871181071171808 1.0 0.9820313697464492 12 P46934 1 +Methionine metabolic process 0.3657149177186676 0.1410210330649054 0.8878533264043855 1.0 0.9821582259343724 7 Q13126 1 +Cellular monovalent inorganic anion homeostasis 0.3436358527676343 0.1388615637638716 0.8895595443117397 1.0 0.9829020035521546 2 P55011 1 +Cellular response to vitamin d 0.3934625854199389 0.1383453365847617 0.8899674965548892 1.0 0.9831895235014588 5 Q8TB36 1 +Response to nutrient 0.2833414361499458 0.1367761449991183 0.8912077399430589 1.0 0.9841098941274112 33 P09601,P30536,P16435 3 +Regulation of receptor internalization 0.3197553460625813 0.1365513267804218 0.8913854515971018 1.0 0.9841098941274112 13 P41440,O75955 2 +Regulation of modification of synaptic structure 0.3845288326301027 0.1350055319792884 0.8926075004907905 1.0 0.9846349934968028 6 Q7L576,Q8WZ74,P60953,Q9UQB8,Q4V328 5 +Multicellular organismal homeostasis 0.2854853042599242 0.1317660451459452 0.895169344373911 1.0 0.986231062810486 67 Q8NF37,Q16739,P04062,P42785,Q6IAN0,P40939,O76024,O00767,O14773,P23786 10 +Regulation of ribonuclease activity 0.3388592301208254 0.1304609834810444 0.8962017209432238 1.0 0.9868005381993968 2 P06748 1 +Regulation of production of molecular mediator of immune response 0.2869194460730065 0.1298479681175145 0.8966867110714969 1.0 0.987106639172028 31 P09601,Q12846,Q9NRA0 3 +Regulation of membrane potential 0.2857601011321403 0.1277851204484317 0.8983190256816629 1.0 0.9878643255459654 65 O75915,P05023,P16615,Q12959,O75844,P04062,P46934,Q9BSK2,Q9UQB8,P05067,P30536 11 +Regulation of mitotic cell cycle spindle assembly checkpoint 0.3607203151378856 0.1276234469904362 0.8984469748501498 1.0 0.9878643255459654 7 P14635,Q5JVF3,Q96SN8,Q13257,Q9Y6G9,P12270 6 +Cellular response to starvation 0.2771704960847209 0.1267492143112029 0.8991388925365658 1.0 0.9878643255459654 36 P13473,P21964,Q96QD8,P04062 4 +Positive regulation of wound healing spreading of epidermal cells 0.3366114076987978 0.12665526328463 0.8992132553182828 1.0 0.9878643255459654 2 P42345 1 +Regulation of integrin activation 0.3366114076987929 0.1266552632846218 0.8992132553182892 1.0 0.9878643255459654 2 Q15058 1 +Axial mesoderm development 0.3887015177065862 0.1257825484679256 0.8999040563515703 1.0 0.9882609727755334 3 P63173,Q8NBL1 2 +Cyclic nucleotide metabolic process 0.3887015177065827 0.1257825484679197 0.899904056351575 1.0 0.9882609727755334 3 P09543,Q01433 2 +Positive regulation of cell activation 0.2844839329812769 0.1246531731092022 0.9007981305946622 1.0 0.9890796170776236 47 P11279,Q9HCL2,Q9NRA0,Q08722,Q12846,P00813,P30825 7 +Negative regulation of peptidase activity 0.2787287562587015 0.1243299877460335 0.9010540047146294 1.0 0.9891973608340248 38 P51812,Q15041,Q15392 3 +Regulation of mitotic recombination 0.394995782963167 0.1232391196744416 0.9019177486423202 1.0 0.9893508774051512 4 P18074,P49959,Q15554 3 +Positive regulation of centriole replication 0.387015177065774 0.1229662494193757 0.9021338241533892 1.0 0.989403526654714 3 P37198,Q6UVJ0 2 +Protein adp ribosylation 0.3228607918362742 0.1224359855594188 0.9025537405288196 1.0 0.9894038578947774 11 Q8IXJ6 1 +Amine catabolic process 0.3790089719860641 0.122126820946976 0.9027985808221528 1.0 0.9894038578947774 6 P0DMN0,P21964 2 +Negative regulation of cell population proliferation 0.2651285459241212 0.1216090952881632 0.9032086099589436 1.0 0.9894038578947774 112 Q12893,Q96G23,P50402,P22466,Q12959,P09493,O95140,P49711,Q99627,Q15392,P09601,O00255,Q92796,Q9NR77,Q13641,Q99623,P04179,P98175,P02545,P05067,P30536,Q8IXJ6 22 +Torc2 signaling 0.3335206518685071 0.1215754949299963 0.9032352217138204 1.0 0.9894038578947774 2 Q96A49 1 +Regulation of modification of postsynaptic structure 0.3844206974128279 0.1191848045156503 0.9051289450740349 1.0 0.9904390836524488 5 Q7L576,P60953,Q8WZ74,Q9UQB8 4 +Regulation of protein dephosphorylation 0.2890178007044054 0.1185778477722733 0.9056098164250954 1.0 0.9905204003142728 29 P04062 1 +Regulation of muscle contraction 0.3007406216527278 0.1182677343057673 0.9058555222326904 1.0 0.9905204003142728 20 P05023,P00813,P16615,Q12959 4 +Positive regulation of oxidative stress induced cell death 0.3838954871568216 0.1181104838210581 0.9059801167111914 1.0 0.9905204003142728 5 Q07820 1 +Negative regulation of telomere maintenance via telomerase 0.3246058558558383 0.1129270205671756 0.9100884140358348 1.0 0.9936619178535274 9 Q96BK5,P09651,Q9H0A0,Q15554,Q01780,Q00839,P07910,Q9NVN8 8 +Cartilage development 0.308930761101573 0.1128622245434758 0.9101397853685758 1.0 0.9936619178535274 15 O75844,P16435 2 +Mechanosensory behavior 0.3279010958134372 0.1127896766361676 0.9101973029654552 1.0 0.9936619178535274 2 Q96SI9 1 +Cytoplasmic pattern recognition receptor signaling pathway 0.3031312898452573 0.1125699281225574 0.9103715273524716 1.0 0.9936891117813186 18 O43657,Q9H078 2 +Extracellular matrix disassembly 0.3338347815284987 0.1107256897970708 0.9118338737266672 1.0 0.9946112836770248 8 O75955 1 +Endosome to lysosome transport via multivesicular body sorting pathway 0.3871239808827637 0.1091807253713955 0.9130591478336956 1.0 0.9948278698155278 4 Q96EY5,Q9UQN3,P55072 3 +Nadh oxidation 0.3778945655980008 0.1084556100940502 0.913634290758244 1.0 0.9952915706328552 3 Q8N335 1 +Negative regulation of translational initiation 0.3527467741037582 0.1071565817068105 0.9146647598127462 1.0 0.9960353716875402 7 P40429,P12270 2 +Regulation of cytoplasmic mrna processing body assembly 0.3766160764474511 0.1065184242213406 0.9151710381541502 1.0 0.996098948591854 3 Q9HBH5,A5YKK6 2 +Negative regulation of fatty acid biosynthetic process 0.3780231014776474 0.1063892912488948 0.9152734892019816 1.0 0.996098948591854 5 P49748 1 +Positive regulation of t cell migration 0.3843126229969014 0.1043786825051949 0.9168688391610154 1.0 0.9975089299683764 4 P05067,Q9H4A3,O95747 3 +Positive regulation of lymphocyte migration 0.3843126229969014 0.1043786825051949 0.9168688391610154 1.0 0.9975089299683764 4 P05067,Q9H4A3,O95747 3 +Heart process 0.2789071745508598 0.103233922025655 0.917777317845348 1.0 0.9979764819041168 33 P05023,P16615,Q12959,P09493,O75844,P00813 6 +Peroxisome fission 0.3752579871226625 0.1010555383970704 0.9195063725155476 1.0 0.9992349622944104 5 Q9Y3D6,P40855 2 +Endothelial cell apoptotic process 0.3813692649112999 0.0994744204901479 0.92076159664277 1.0 1.0 4 Q4KMQ2 1 +Cardiac muscle cell action potential 0.3056854302668363 0.0955910391786345 0.9238453823083332 1.0 1.0 14 P16615,Q12959 2 +Multicellular organism growth 0.2750736702754164 0.0951502832922318 0.9241954589247006 1.0 1.0 34 Q15363,O75844,Q6KCM7,O95470 4 +Positive regulation of bone mineralization 0.378001203165357 0.094016894174005 0.9250957365689596 1.0 1.0 4 Q4KMQ2 1 +Muscle cell development 0.2717965224572736 0.0922405842944354 0.9265068938678354 1.0 1.0 35 P16615,Q16527,P09493,O75844,P02545,P12814 6 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.3163484465970121 0.0875982259046309 0.9301960122832852 1.0 1.0 9 O43681,P46379 2 +Regulation of aspartic type peptidase activity 0.3622821810005696 0.0864067703440857 0.9311430651054876 1.0 1.0 3 P49755,O75116 2 +Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process 0.3622821810005696 0.0864067703440857 0.9311430651054876 1.0 1.0 3 P49755,O75116 2 +Receptor internalization 0.2912283377305356 0.086073358166158 0.9314081021122892 1.0 1.0 23 P41440,O75955,P46934 3 +Sphingomyelin metabolic process 0.3622034726067697 0.0859379574367385 0.9315157374388512 1.0 1.0 6 O15269,Q9P0L0 2 +Negative regulation of platelet derived growth factor receptor signaling pathway 0.3048609159876371 0.0826233495562522 0.93415103449064 1.0 1.0 2 O14964 1 +Negative regulation of protein containing complex assembly 0.2780151975133194 0.0811506932547275 0.9353221112039588 1.0 1.0 44 P45880,P04062 2 +Pigment granule localization 0.3619235095613144 0.0770053520785994 0.9386192872697754 1.0 1.0 5 Q13561,Q96AX1,Q9H267,P62820 4 +Regulation of calcium mediated signaling 0.3209661744052791 0.0756028703460729 0.939735052796714 1.0 1.0 8 Q8IWX8,P00813 2 +Vesicle mediated transport in synapse 0.2752496296683883 0.0753475103134455 0.9399382211241236 1.0 1.0 41 Q9P253,P16615,P27824,O14656,Q7L0J3,Q5SQN1,Q12846 7 +Regulation of striated muscle contraction 0.3062927914147227 0.0737749895228393 0.941189428249686 1.0 1.0 12 P16615,Q12959 2 +Regulation of nervous system process 0.3000993444352734 0.0736265199470997 0.9413075685384223 1.0 1.0 14 P04062,Q9UQB8 2 +Monocyte chemotaxis 0.3185539253103148 0.0694060166234543 0.9446664398977516 1.0 1.0 8 Q4KMQ2 1 +Neurotransmitter metabolic process 0.3568324732920649 0.0685525098473951 0.94534582153612 1.0 1.0 5 P21964 1 +Dendrite extension 0.3362408553742343 0.0684886761486775 0.9453966340344948 1.0 1.0 7 Q7L576,Q9NZM3,O60271,Q9Y263,Q96F07,Q92581 6 +Regulation of dna dependent dna replication 0.2893030944262947 0.0675706506204229 0.9461274193960878 1.0 1.0 22 O95785,O75844,Q9Y248,Q9BRT9 4 +Response to thyroxine 0.3445756042720731 0.0655181000772819 0.947761495520056 1.0 1.0 3 P48506,P48507 2 +Regulation of calcium ion transmembrane transport 0.2899085768491812 0.0653440099145148 0.9479001023517756 1.0 1.0 21 P21796 1 +Glycoprotein catabolic process 0.3440589739478146 0.0649718065723138 0.9481964479067432 1.0 1.0 3 Q8TCJ2 1 +Epithelial cell apoptotic process 0.3002652384460196 0.0622589885744439 0.9503565874625616 1.0 1.0 13 P09601,Q4KMQ2,O76024 3 +Regulation of mitochondrial membrane potential 0.2882863763454983 0.0620765928637668 0.95050183722936 1.0 1.0 22 Q9BSK2 1 +Positive regulation of g protein coupled receptor signaling pathway 0.3406408094435149 0.0614448168183201 0.9510049611039512 1.0 1.0 3 P35232,P49840 2 +Membrane to membrane docking 0.3403597526700483 0.0611615238872687 0.9512305718290974 1.0 1.0 3 P26038,P15311 2 +Adaptive thermogenesis 0.2817165056404725 0.0608418781664249 0.951485138125686 1.0 1.0 28 Q6IAN0,O00767,P23786,P12235,P40939 5 +Muscle cell apoptotic process 0.2962342083624546 0.0602348755216245 0.9519685694821884 1.0 1.0 15 P09601,P04179,O95140 3 +Telomeric d loop disassembly 0.33867341202924 0.0594829887990394 0.9525674144556746 1.0 1.0 3 Q14191,Q15554 2 +Telomeric loop disassembly 0.33867341202924 0.0594829887990394 0.9525674144556746 1.0 1.0 3 Q14191,Q15554 2 +Regulation of transcription regulatory region dna binding 0.3015878037287559 0.0578688176255832 0.9538531214124836 1.0 1.0 12 O75844 1 +Regulation of stem cell differentiation 0.2888872670039613 0.0566725953775065 0.9548060046397432 1.0 1.0 20 Q9Y6C9 1 +Polarized epithelial cell differentiation 0.3054617117117112 0.0565471169651007 0.9549059616343808 1.0 1.0 9 P15311,P61586,P60953,Q14160,Q9P1Y5,P61026,Q13308,P26038 8 +I kappab phosphorylation 0.3506288001243344 0.0556789255551859 0.9555975884242648 1.0 1.0 4 Q96HY6 1 +Nuclear migration 0.2950601080056861 0.054546007958729 0.9565001540743387 1.0 1.0 14 Q9UH99,Q5SNT2 2 +Regulation of mitochondrial rna catabolic process 0.3464566929133908 0.0525626004197982 0.9580804162969409 1.0 1.0 5 Q9GZT3,P42704,Q8IYB8,Q12849 4 +Response to abiotic stimulus 0.2710443267293215 0.052503845686558 0.9581272311484732 1.0 1.0 242 Q9UMX0,Q13432,P30519,P22830,Q8N511,Q70UQ0,P55786,O95202,P08183,Q12770,P09601,Q96A26,Q9BRK5,P04062,P46934,Q96QD8,P00403,P49748,O75844,Q9H078,Q9Y4P3,P27544,Q99623,P02545,P30536,P00813,Q8IXJ6 27 +Positive regulation of cysteine type endopeptidase activity 0.2691508919172902 0.0505950098672329 0.9596482392835012 1.0 1.0 34 Q9BXK5,O75915,Q9NZJ7,Q96A26,Q9P0J0 5 +Anterograde dendritic transport 0.3455312229757222 0.0496908853997467 0.9603687198854018 1.0 1.0 4 Q14254 1 +Homocysteine metabolic process 0.3257448004496982 0.0477899827307075 0.9618836200586096 1.0 1.0 3 P22033,P25325 2 +Monovalent inorganic anion homeostasis 0.3438290694405408 0.0477690720300847 0.9619002853504734 1.0 1.0 4 Q9Y666,Q9BXP2,P55011 3 +Regulation of g protein coupled receptor signaling pathway 0.2932055257964458 0.0477036889929986 0.961952394060782 1.0 1.0 14 Q8TEY7,P35232,P16949,O75116,P23634,P04899,O14744,Q13464,P31946,Q96SB3,P00813,P50570,P49840 13 +Smooth muscle cell apoptotic process 0.3248701492319054 0.0448171178841019 0.9642530807034266 1.0 1.0 7 P04179,O95140 2 +Regulation of neural precursor cell proliferation 0.291938335385501 0.0434559873434748 0.9653380483708858 1.0 1.0 15 Q8IXJ6 1 +Pigmentation 0.2884939838639839 0.0431687126006 0.965567045556638 1.0 1.0 18 P04179,Q8TAA9,Q86YV9 3 +Extracellular matrix assembly 0.3381153305204029 0.0421395427204374 0.96638745762029 1.0 1.0 6 P11047,Q96AY3,O75122,O60568,P07942 5 +Basement membrane assembly 0.3380202474690684 0.0407682231259304 0.967480672559824 1.0 1.0 5 P11047,P07942,O60568,O75122 4 +Wound healing spreading of epidermal cells 0.3368006747258915 0.0402376918713382 0.9679036281824658 1.0 1.0 4 P42345,O75122,Q7Z460 3 +Regulation of wound healing spreading of epidermal cells 0.3368006747258915 0.0402376918713382 0.9679036281824658 1.0 1.0 4 P42345,O75122,Q7Z460 3 +Basement membrane organization 0.322172200337661 0.0395588292152578 0.9684448512540832 1.0 1.0 7 P11047,O75122,O60568,P07942,Q7Z460,P05556 6 +Regulation of dendrite extension 0.3359572673601358 0.0393770125175083 0.9685898070459018 1.0 1.0 4 Q9Y263,Q9NZM3,O60271 3 +Post embryonic development 0.2899705669183416 0.0380375354905145 0.9696577546778722 1.0 1.0 16 O95470 1 +Copii coated vesicle cargo loading 0.296723166973917 0.0342676138844542 0.9726637500708382 1.0 1.0 10 Q12770 1 +Regulation of dna dependent dna replication initiation 0.3294911442226612 0.0330780464935699 0.9736123495284372 1.0 1.0 4 Q9ULV3,P24941,O95251 3 +Regulation of sodium proton antiporter activity 0.3049465992130493 0.0330221936164563 0.97365688934446 1.0 1.0 3 Q9UHD1,O43707 2 +Positive regulation of phosphoprotein phosphatase activity 0.3283666010683189 0.0320358711076081 0.9744434445623116 1.0 1.0 4 Q15257,P08238,P42345 3 +Positive regulation of cell junction assembly 0.2933155462172223 0.0313073786543846 0.9750244059786548 1.0 1.0 12 P41440,O75955 2 +Retina development in camera type eye 0.283868156162069 0.0312196814559609 0.97509434403191 1.0 1.0 19 Q8NF37 1 +Positive regulation of muscle contraction 0.3173311683138338 0.0304680723351719 0.975693756139442 1.0 1.0 7 P00813 1 +Glomerular epithelial cell development 0.3004496908375562 0.0304231006690538 0.9757296217111512 1.0 1.0 3 P11047,P46940 2 +Adenosine to inosine editing 0.2993254637436838 0.0298038001317979 0.9762235280476128 1.0 1.0 3 Q86U44,Q96DE0 2 +Negative regulation of binding 0.2686814187391018 0.0289954583106696 0.9768682128159498 1.0 1.0 40 P09601,P16615,O75381,P30533,Q6IAN0,P10586,Q96GD4 7 +Positive regulation of phosphatase activity 0.3284589426321774 0.0286785174449762 0.977120989915301 1.0 1.0 5 Q15257,P08238,Q13464,P42345 4 +Sphingomyelin biosynthetic process 0.3226803766797846 0.0270018917238456 0.9784582252052864 1.0 1.0 4 O15269 1 +Regulation of cytoplasmic transport 0.287397750306515 0.0269176189337382 0.9785254407318728 1.0 1.0 14 Q9UL25,P35241,P53367 3 +Phototransduction visible light 0.2922990444069784 0.0261979809090289 0.9790994263322516 1.0 1.0 3 Q15555,P29992 2 +Establishment of lymphocyte polarity 0.2892074198988266 0.0247504936419286 0.980253979297154 1.0 1.0 3 Q14160,Q14254 2 +Epithelial cell proliferation 0.2732847108106017 0.0224571215636437 0.9820833154009097 1.0 1.0 48 P09601,Q12959,Q9NQC3,Q99623,Q8WTV0 5 +Long term synaptic potentiation 0.2882547785718527 0.0214835172781357 0.9828599517361476 1.0 1.0 13 Q92542,P05067,Q9Y639,Q12846 4 +Transcytosis 0.3121943873754861 0.0213041258030394 0.9830030526721928 1.0 1.0 7 P55899 1 +R loop disassembly 0.3129041326960948 0.0192356285215861 0.9846531354051616 1.0 1.0 4 P78362,Q9NY93,Q9NR30 3 +Calcineurin mediated signaling 0.2967355221424611 0.0190538093066737 0.98479817956615 1.0 1.0 8 P0DMN0,Q8IWX8 2 +Vascular endothelial growth factor receptor signaling pathway 0.2903643963281535 0.0180565238531953 0.9855937612303618 1.0 1.0 9 Q13177,P04792,Q16539,P46934 4 +T cell proliferation 0.2765234555454386 0.0177744519052869 0.9858187859664906 1.0 1.0 26 Q92542,Q9HCL2,Q12959,P09429,P30825 5 +Adherens junction assembly 0.3100927748102325 0.0172017253378504 0.986275685773049 1.0 1.0 4 P18206,P35222,Q13177 3 +Neural nucleus development 0.2838100773824381 0.0167926609534227 0.9866020247836618 1.0 1.0 17 Q8IXJ6 1 +Receptor localization to synapse 0.2847352545805376 0.0165514474219432 0.9867944585897616 1.0 1.0 15 Q9Y639,Q92796,O15400,Q12959 4 +Meiotic spindle organization 0.289777527457062 0.0159549510137957 0.987270330998421 1.0 1.0 10 O14965,Q08379,O14777,P30153,Q14674,P46100,P23258,Q12768,O95067 9 +Olfactory lobe development 0.2630691399662805 0.0154676432559767 0.9876590983453266 1.0 1.0 3 Q02218,Q15058 2 +Negative regulation of ion transmembrane transporter activity 0.2844195941106386 0.0154084379905291 0.9877063316835692 1.0 1.0 15 P46934 1 +Regulation of dna directed dna polymerase activity 0.2891182008055017 0.01512108050197 0.987935583075514 1.0 1.0 9 Q9Y248 1 +Mitochondrial dna repair 0.316085489313838 0.0149754933084433 0.9880517316976504 1.0 1.0 5 P51530,Q9BQP7,P49916,P04637 4 +Rab protein signal transduction 0.307681422410387 0.0136603910773057 0.989100923838627 1.0 1.0 7 P20338,P51151,Q9UL25,Q15286 4 +Lipophagy 0.3145555260347289 0.01342814546723 0.9892862120287248 1.0 1.0 5 O15269 1 +Negative regulation of cell death 0.2684819406956826 0.0132674297325222 0.9894144332093164 1.0 1.0 238 Q86XL3,Q15041,P21796,Q9NVI7,P45880,O15118,Q01105,Q07820,O76024,P46379,Q8IWB1,Q9H4A6,P12235,P05141,P50897,Q15392,P09601,Q9HCL2,Q9H3K2,P0DMN0,P04062,P16435,O60313,P51812,Q12981,O95881,Q9P0J0,Q99623,P02545,Q86UE4,P00813 31 +Mitochondrial dna metabolic process 0.3161744022503533 0.0104505514873847 0.9916618180910196 1.0 1.0 6 P36776,Q9BQP7,P51530,P04637,P49916 5 +Muscle cell cellular homeostasis 0.3135611514338485 0.0071807561985103 0.9942706347318196 1.0 1.0 6 P13473 1 +Endosome organization 0.2617050372176491 0.0067476451309351 0.9946161989829994 1.0 1.0 36 Q9P253,Q14108 2 +Negative regulation of reproductive process 0.3130826489258986 0.0065933484517274 0.9947393071820876 1.0 1.0 6 P00813 1 +Synaptic vesicle cytoskeletal transport 0.304555680539933 0.0040780127938379 0.9967462255715228 1.0 1.0 5 O95295,Q9Y2T2,Q92572,O14617 4 +Inner cell mass cell proliferation 0.3108298171589339 0.0038744906084255 0.9969086114970512 1.0 1.0 6 O75312,P61201,Q9BRT9,Q86XI2,Q9Y3A5 5 +Positive regulation of membrane potential 0.3007033111837791 0.0008182175765545 0.9993471569011338 1.0 1.0 5 Q9UJZ1 1 +Visual behavior 0.2870501382287291 1.867829090129857e-05 0.9999850968800684 1.0 1.0 8 P05067,P04035 2 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..49dac1d3fd4e5ab043aa10c2aed065a804c32d86 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular node development", "Atrioventricular valve development", "Atrioventricular valve formation", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B 1 b cell differentiation", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in prostate gland morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Camp metabolic process", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac myofibril assembly", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell cytokine production", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell differentiation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cocaine", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nicotine", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chiasma assembly", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Choline transport", "Chondroblast differentiation", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common bile duct development", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Convergent extension involved in gastrulation", "Convergent extension involved in organogenesis", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transmembrane transport", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal cell differentiation", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardial cell differentiation", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat pad development", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Follicle stimulating hormone secretion", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of anatomical boundary", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glomerulus morphogenesis", "Glomerulus vasculature morphogenesis", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Hard palate development", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve formation", "Heart valve morphogenesis", "Heat acclimation", "Heat generation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Induction of positive chemotaxis", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 4 production", "Interleukin 5 production", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron ion homeostasis", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens fiber cell morphogenesis", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymph vessel development", "Lymph vessel morphogenesis", "Lymphangiogenesis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of animal organ identity", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Marginal zone b cell differentiation", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Melanosome assembly", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesendoderm development", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Nail development", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of camp mediated signaling", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle cell differentiation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cardiocyte differentiation", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of catecholamine secretion", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular extravasation", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of dopamine secretion", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of granulocyte differentiation", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of hexokinase activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 beta production", "Negative regulation of interleukin 1 production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil activation", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor mediated signaling pathway", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Negative t cell selection", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural fold formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal signal transduction", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Nodal signaling pathway", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Notochord development", "Notochord morphogenesis", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast development", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otic vesicle development", "Otic vesicle formation", "Otic vesicle morphogenesis", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl l cysteine s palmitoylation", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericardium development", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Peristalsis", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phasic smooth muscle contraction", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of bicellular tight junction assembly", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cd8 positive alpha beta t cell differentiation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of corticosteroid hormone secretion", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of gonadotropin secretion", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of hair follicle maturation", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of heat generation", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 13 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 4 production", "Positive regulation of interleukin 5 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic cell cycle phase transition", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of mucus secretion", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein kinase c signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid hormone secretion", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper 17 cell differentiation", "Positive regulation of t helper 17 type immune response", "Positive regulation of t helper 2 cell cytokine production", "Positive regulation of t helper 2 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type 2 immune response", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of uterine smooth muscle contraction", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prostate gland morphogenesis", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c activating g protein coupled receptor signaling pathway", "Protein kinase c signaling", "Protein linear polyubiquitination", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to site of double strand break", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein palmitoylation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reduction of food intake in response to dietary excess", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen processing and presentation", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of blood vessel remodeling", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in ureteric bud morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell differentiation", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cd8 positive alpha beta t cell differentiation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endosome to plasma membrane protein transport", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of gonadotropin secretion", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of growth rate", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of heat generation", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of luteinizing hormone secretion", "Regulation of lyase activity", "Regulation of lymphangiogenesis", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil activation", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil degranulation", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast development", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of positive chemotaxis", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snare complex assembly", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 17 cell differentiation", "Regulation of t helper 17 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type b pancreatic cell proliferation", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cycloheximide", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to fluoride", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to luteinizing hormone", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Strand invasion", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell cytokine production", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymic t cell selection", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transforming growth factor beta2 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the c end degron rule pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Ureter development", "Ureter morphogenesis", "Ureteric bud elongation", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP5M1", "APEH", "APEX1", "API5", "APIP", "APLP2", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARID4A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRIP1", "BRIX1", "BRMS1L", "BRPF3", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C16orf62", "C17orf75", "C19orf70", "C1QBP", "C21orf59", "C2CD5", "C2orf49", "C5orf51", "C8orf59", "CAB39", "CACTIN", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC8", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC123", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPI", "CENPK", "CENPQ", "CENPV", "CEP250", "CEP290", "CEP350", "CEP44", "CEP55", "CEP97", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHML", "CHMP1A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLN5", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG4", "COG5", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD7", "COMMD9", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENND4C", "DENR", "DEPDC1B", "DERL1", "DERL2", "DFFA", "DFFB", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAIM", "FAM120B", "FAM129B", "FAM162A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXL18", "FBXO21", "FBXO22", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1B", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FOXK1", "FOXRED1", "FPGS", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAN", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUSB", "GXYLT1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISG20L2", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2B", "ITPA", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KANSL3", "KARS", "KAT7", "KCMF1", "KCTD10", "KCTD12", "KCTD15", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIN", "KLC1", "KLC2", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIG4", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRR1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYPLA1", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MALT1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP7D3", "MAP9", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL43", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVB12A", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NEO1", "NES", "NF1", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN3", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OIP5", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHPT1", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCD3", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA2", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POM121C", "PON2", "POP1", "POP7", "POR", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN9", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RMND1", "RMND5A", "RNASEH2A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD1", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDE2", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC14L2", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGSH", "SGTA", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPRH", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT1A4", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF10", "TAF2", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D24", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX2", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGS1", "THADA", "THAP11", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THTPA", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLK2", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMCO6", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM56", "TRIO", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TSR3", "TSTA3", "TTC1", "TTC19", "TTC37", "TTC4", "TTF2", "TTI1", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE3D", "UBE4A", "UBE4B", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USE1", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP32", "USP33", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS11", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS52", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR41", "WDR43", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WDR92", "WFS1", "WIPI2", "WIZ", "WLS", "WNK1", "WRAP53", "WRAP73", "WRN", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YES1", "YIF1A", "YIF1B", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZDHHC20", "ZFAND1", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["AATF", "ABCB1", "ABCC1", "ABCD3", "ABCD4", "ABHD10", "ABHD12", "ACADVL", "ACAP2", "ACAT2", "ACOX3", "ACP2", "ACP6", "ACSL6", "ACTN1", "ACTN4", "ACVR1B", "ADA", "ADD1", "ADI1", "ADK", "ADPGK", "AFG3L2", "AGK", "AGPAT5", "AGPS", "AHCTF1", "AIFM1", "AIP", "AK3", "ALDH3A2", "ALG1", "ALG11", "ALYREF", "AMPD2", "ANKLE2", "ANO6", "ANXA1", "ANXA2", "AP2M1", "AP3D1", "AP3M1", "AP3S1", "AP5M1", "APLP2", "APOL2", "APOOL", "APP", "ARFIP1", "ARFIP2", "ARHGAP1", "ARL1", "ARL6IP1", "ARL6IP5", "ARL8B", "ASAH1", "ASNA1", "ASPH", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP7B", "ATPAF1", "ATRX", "AUP1", "AURKA", "AURKB", "B4GAT1", "BAG5", "BAG6", "BAIAP2", "BANF1", "BCAP31", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BICD2", "BNIP1", "BOP1", "BSG", "C12orf73", "C19orf70", "C1QBP", "C2CD5", "CADM1", "CAMSAP3", "CANX", "CARS", "CCDC22", "CCDC47", "CCDC51", "CCNB1", "CCNB2", "CD47", "CDC40", "CDC42", "CDH2", "CDIPT", "CDK2", "CDK5RAP2", "CELF2", "CENPK", "CENPV", "CERS1", "CERS2", "CERS5", "CETN2", "CHCHD3", "CHERP", "CHID1", "CHMP2B", "CHORDC1", "CHST14", "CIZ1", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLN5", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLUH", "CNNM4", "CNOT1", "CNP", "CNPY2", "COA3", "COMT", "COPS2", "COPS3", "COPS4", "COPS5", "COPS8", "COQ8A", "COX14", "COX2", "COX4I1", "COX7A2", "COX7C", "CPT1A", "CPT2", "CRTAP", "CSGALNACT2", "CSNK1A1", "CSRP2", "CTCF", "CTNNB1", "CTSA", "CTSC", "CTTNBP2", "CWC27", "CXADR", "CYB5B", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DARS2", "DCAKD", "DCTN2", "DCTPP1", "DDRGK1", "DDX18", "DDX21", "DDX56", "DEGS1", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DLG1", "DLG3", "DMAP1", "DNA2", "DNAJB12", "DNAJC1", "DNAJC11", "DNAJC3", "DNM1L", "DNM2", "DOCK1", "DOLPP1", "DSC3", "DYM", "DYNC1LI1", "ECE1", "ECH1", "EEF1E1", "EHD1", "EHD4", "EI24", "EIF2B2", "EIF4G1", "EMC1", "EMC3", "EMC4", "EMC7", "EMD", "ENY2", "EPDR1", "EPHA7", "EPHX1", "EPS15L1", "ERAP1", "ERCC2", "ERG28", "ERGIC1", "ERGIC3", "ERLIN1", "ERMP1", "ERO1A", "ESPL1", "ESYT2", "ETFDH", "EXOC7", "EXOSC10", "EZR", "FADS2", "FAF2", "FAM129B", "FAM162A", "FAM3C", "FAM8A1", "FANCA", "FANCD2", "FAR1", "FBL", "FCGRT", "FDFT1", "FECH", "FEM1B", "FIS1", "FKBP10", "FKBP14", "FKBP7", "FLOT1", "FLOT2", "FNTA", "FOXRED1", "FTSJ3", "FUCA1", "G3BP2", "GAA", "GAL", "GALNT1", "GALNT4", "GALNT7", "GBA", "GCLC", "GCLM", "GDAP1", "GFM1", "GGCX", "GHITM", "GINS2", "GINS4", 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setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Organelle subcompartment 176 404 7.35843486945377 1.860790066352059e-13 115.97815533980582 370.4077669902912 1.8466078375892352 0.461199583276842 45.24176702976874 43.040100266333 2.697642340677977 0.4541841641473397 5.890216234085273e-21 3.692709908347348e-06 3.871996109134076e-12 1.5103210128000352e-27 1.224724268908762e-43 +Endoplasmic reticulum 227 518 7.235932305743015 4.623419091804118e-13 139.71116504854368 475.50728155339806 1.972579372344309 0.4597126503683645 50.29410175615224 47.94654634280014 2.8130551221954065 0.458598772128197 1.6938796638172456e-21 3.130449552194856e-06 3.528945385257575e-12 3.226433811466948e-26 2.16479456411976e-45 +Nuclear outer membrane endoplasmic reticulum membrane network 153 330 6.728632507560504 1.712649915879431e-11 98.3519417475728 305.0218446601942 1.8626549185660248 0.4346737740195964 40.114822105305365 33.029069404441934 2.648813561163414 0.4525721946789457 3.89477939288372e-21 1.1880593233541405e-07 1.0996078181471489e-13 2.968575152825115e-28 8.828568179539059e-44 +Organelle inner membrane 137 248 6.3081190528477045 2.8244692553734707e-10 79.6747572815534 237.5995145631068 1.5941979045672914 0.3906136455525962 32.81710191865129 21.467005610038825 2.570753705211445 0.4244355950981394 1.113241579080219e-16 5.611701719035701e-07 1.930102580538691e-12 5.757134627021979e-20 1.7747468288407197e-45 +Intrinsic component of organelle membrane 92 149 6.178099003577597 6.487802820115686e-10 52.51699029126213 129.34223300970874 2.0732064315361294 0.2796588394070637 24.692225942786415 15.820346456508432 2.8130846896968285 0.39829365000917 1.4270812966950802e-12 0.0120718653861833 0.0001168485709592 8.385088219491301e-17 1.682784877637527e-39 +Mitochondrial envelope 155 321 6.164496274602712 7.070786172853464e-10 98.51456310679612 309.05582524271847 1.3784407074331837 0.4315621435689855 37.853540978552445 29.592036616547553 2.6690149272426917 0.4358105924461398 1.39304769291715e-16 1.3411502482885699e-09 2.662110801386939e-12 1.3495829867941337e-19 5.44236452485955e-43 +Envelope 191 512 6.016497170043612 1.782316127105993e-09 133.55825242718447 476.99271844660194 1.1125762168925015 0.4931727688685032 47.82674034566458 40.415168802184624 2.6300132137901633 0.4489464989697134 2.0975936345538137e-18 1.552917668980859e-07 6.4891549092862794e-12 1.8753018839220348e-23 4.457652803711993e-46 +Mitochondrial protein containing complex 70 160 4.959025452412706 7.084768559437946e-07 45.62621359223301 153.59708737864077 0.8032126729603613 0.4024101172023991 21.080430630469312 12.423857071229754 2.191669513941161 0.4117346592056412 7.806470009470359e-08 1.516450345347378e-08 1.3317377405996878e-08 5.769896142550898e-11 3.105154279911908e-20 +Membrane protein complex 135 318 4.701554934408806 2.581877804219701e-06 80.6747572815534 286.40291262135923 0.8072324880333213 0.5482017098759524 27.14508025817277 25.65052264389531 1.8803092756171496 0.4277745875695662 1.0292570067074254e-05 1.0757258812900411e-06 3.134809129362652e-06 3.886072306948885e-07 6.480972376277515e-20 +Intrinsic component of endoplasmic reticulum membrane 41 60 4.507229426851848 6.567960431747011e-06 21.439320388349515 53.03155339805825 1.5445183869163015 0.2945609219212759 9.936629672422429 6.151523176643304 2.1054078800196185 0.3580268322643601 3.186221650656315e-08 0.0201277687112906 0.001182728525427 1.3375435314936276e-11 7.7371207555099e-19 +Golgi membrane 52 143 4.450375631116191 8.572022404118584e-06 41.28398058252427 131.19174757281553 1.6327747521284677 0.3511039607499193 15.277988344159814 17.44963987873233 1.926180921267262 0.4033858283713009 4.289871390281244e-05 0.0448888789045046 0.006540226970369 8.940399807819839e-07 1.013702351477402e-09 +Inner mitochondrial membrane protein complex 40 77 4.403591022019459 1.0647358078319512e-05 27.97087378640777 75.4635922330097 1.520604987560478 0.2664687480104057 12.043574857699111 6.447783897817093 2.3558486082891616 0.3692317407906862 4.1876162924051363e-07 2.1236559567084524e-06 4.12230200308475e-07 2.5413109829216503e-10 5.094658273400284e-19 +Outer membrane 41 95 4.176382250992303 2.9618194722358385e-05 28.936893203883496 87.79611650485437 1.4859238244628277 0.3236686433663402 11.632349354832256 8.24751710010496 1.9336855473946637 0.38878066573106 8.47053945300794e-08 1.7081503572790947e-05 4.934295516025085e-05 9.698976075290651e-09 3.4481184741217256e-14 +Lysosomal lumen 21 35 4.110328053965094 3.9509739762078055e-05 18.075242718446603 34.54368932038835 0.7848519845050315 0.1014568164283454 6.206531846566726 3.2976210873168883 3.038689298289951 0.2012423645269794 2.226612919685336e-07 0.2703718142220204 0.0004347448507531 4.987473339927188e-07 3.199355812211421e-13 +Intrinsic component of mitochondrial inner membrane 24 34 4.013919368954345 5.971875385979431e-05 13.946601941747574 31.446601941747577 1.7062420859184484 0.2149692261988765 6.992163651608136 3.3601842163433866 1.8185871159494191 0.3070405082296492 2.1646660609841717e-05 0.0221396463905691 0.0012201132329283 2.2087414145039963e-06 2.5049565161582026e-15 +Intrinsic component of plasma membrane 51 92 3.957403296518724 7.57689457300259e-05 29.711165048543688 79.49271844660194 0.9914207279546418 0.2992612012372248 13.467745416506318 12.62980929789956 2.1277799030157807 0.3627370007757806 0.2870926494827699 0.6411579503472646 0.646892792571798 0.1443752551553142 0.0268324849694537 +Golgi apparatus 103 353 3.952060071928169 7.74812831016991e-05 79.29126213592232 307.80825242718447 1.0941692666231844 0.5225509759640199 24.90716006851961 39.34912971804267 1.7376904428153446 0.4394682295132952 0.0005163617559019 0.3220087220123724 0.0262931253573344 1.0554000849436448e-05 7.7754930861397e-09 +Intrinsic component of mitochondrial membrane 34 51 3.801358024572396 0.0001439051883664 20.225728155339805 46.883495145631066 1.6360090381123027 0.2606204408334349 9.735582728924424 5.567853242112672 2.0682718238883013 0.3438986948818692 0.0004128084366694 0.0512049491784678 0.0064708018379125 9.974382266125103e-05 1.3466676503184764e-14 +Vacuole 62 239 3.741854613175428 0.0001826671886138 55.029126213592235 212.35679611650485 0.7895788564169173 0.4204713883128338 16.092847298969616 21.031446114270427 2.221429361906059 0.4148180554719883 1.1188625501310257e-07 0.1176524843696369 6.909425213030685e-05 1.586181323876761e-07 2.1933359285572686e-10 +Vacuolar membrane 37 137 3.60030081614407 0.0003178492396267 31.91504854368932 121.20631067961163 0.8693310080509177 0.3422944242486927 10.598363436017626 13.850227259030053 1.9844114292962869 0.3837860427998523 7.116699324260844e-05 0.0688524176600546 0.004383474167669 0.0001501131574069 2.038391268249115e-06 +Mitochondrion 181 652 3.585836383932519 0.0003359995825142 150.5606796116505 610.75 0.3893280889581553 0.5444893646695418 55.48150839960472 53.47985851692477 2.1394883185001157 0.4272675793576402 6.581330986656074e-11 1.2153387879653774e-05 2.483329454569159e-07 1.6101472101121254e-14 1.5787296569888043e-26 +Respirasome 20 45 3.451512072010818 0.0005574548183373 15.08495145631068 43.37378640776699 1.2524823540042158 0.2922262294299136 6.290312072426717 4.489587979561489 1.7783434517583476 0.3462844006183536 0.0001043370662097 0.0006106679300335 0.0001430296995978 6.908838981678768e-07 3.350201683533605e-10 +Endoplasmic reticulum protein containing complex 39 67 3.433874287611535 0.0005950200849671 20.067961165048544 61.213592233009706 0.544324442160867 0.4875881372361492 7.672624563199495 5.300944201362535 1.5348103009085623 0.3893079894443684 0.0389154034062281 0.0883749201119629 0.0815689737113107 0.0142757790525967 1.4002833316106934e-05 +Nuclear inner membrane 14 23 3.146540161641718 0.0016521456986184 7.347087378640777 20.57281553398058 1.3204335588742686 0.2519451141048848 3.6006224195129035 1.9968516080603145 1.2188770932171689 0.2896682474252494 7.607804876393382e-05 0.1767085987036181 0.000628041464815 5.270338266925529e-06 4.453847995224881e-09 +Vacuolar lumen 23 66 3.124533663942279 0.001780871428809 22.262135922330096 63.33980582524272 0.6562244405592584 0.1887666227175413 6.920437110961116 4.902057024259538 2.8947011026985514 0.298290072492813 4.456687930400114e-06 0.4139412402378241 0.0045262042194575 3.1359916965687687e-06 7.754047591370501e-10 +Azurophil granule membrane 10 23 2.988278096597795 0.0028055414700618 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 0.0011191379394124 1.0 0.0695193554582273 0.0007104965070469 8.145144712243562e-06 +Endoplasmic reticulum golgi intermediate compartment 22 50 2.94789191335497 0.0031994891033086 14.888349514563108 49.49271844660194 1.4759277407874345 0.3201471070907981 6.47003250199477 5.053350843348441 1.420924643396655 0.3585240832471577 0.0014983080031188 0.0102837000877503 0.0022694974716314 0.0005162166791491 0.000791031529329 +Late endosome 22 79 2.931147231828824 0.0033771268270319 15.655339805825244 65.18203883495146 0.1482522199608934 0.3683478922291265 6.675389202214119 9.543379127098556 1.7080817701484334 0.368772234437858 0.0002216895003449 0.6158759206318899 0.1276978861077169 0.0035522581613711 0.0045879682391284 +Endoplasmic reticulum golgi intermediate compartment membrane 15 28 2.912846372539323 0.0035815075359635 10.49271844660194 25.839805825242717 1.5441023898993702 0.2324243418613106 5.505729177420246 3.7718384126099376 1.49831312620529 0.2965572765953523 0.0025071770567847 0.0020362011066544 0.0149054294280594 0.0002989066385229 0.0002489131742275 +Transporter complex 32 64 2.875783986217888 0.0040302542020915 16.033980582524272 55.199029126213595 0.256193630237002 0.358562058071074 7.704418772430675 7.665912382074106 1.666161547187811 0.3440522205931707 0.0141616065048842 0.0305266349758198 0.0026816889524175 0.0086717958939406 2.098270418499907e-06 +Secretory granule membrane 22 74 2.804260261048128 0.0050432177475701 19.699029126213592 69.8495145631068 0.9295860214656708 0.3887665887416008 7.284889203542463 7.49087955205396 1.5950364553562375 0.3903287060113383 0.0933439842200765 0.5699110967205412 0.2427763389694352 0.0110656344361502 1.8113240986787404e-05 +Microbody membrane 20 30 2.7999484023590475 0.0051110775571214 9.83980582524272 26.8373786407767 1.0322166739723002 0.3740701224912098 5.101262737371427 4.075770333088885 1.3138416014090577 0.3534887732287703 0.0752344556072313 1.0 0.4176693971260321 0.0459551502585406 0.000337159038506 +Lipid droplet 8 33 2.764338075561857 0.0057038408737017 7.313106796116505 30.72087378640777 0.9597061621709796 0.3916106255858687 3.663189105886808 2.181620314734523 1.1934081113966928 0.3497541884861006 0.0055336707658233 0.0370108517080311 0.0241494832296601 0.0009197246197011 0.0011188813818622 +Outer mitochondrial membrane protein complex 10 16 2.761542498402524 0.0057529028908633 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 0.0046437067491223 0.0037480987371249 0.0008209706516698 0.0011116174795585 7.180176827125465e-09 +Cytochrome complex 7 15 2.7121034626453464 0.0066857721169419 6.021844660194175 16.08495145631068 1.0267019648816196 0.2321293206617183 2.9315837025395948 1.6175814223208935 1.624269406530766 0.2919563386676546 0.0014543884916538 0.0003084061297489 0.0024749889228003 0.0005384549749284 4.711594946064534e-05 +Oxidoreductase complex 28 65 2.6996616611945328 0.006941002441078 16.138349514563107 58.1747572815534 0.4112275970760134 0.4385210691837483 8.292749505639035 5.03902669070441 1.4297411393453454 0.366860872580609 0.0018882839571105 0.0012104799157991 0.000387375023138 0.0001480503499616 6.3720309462057184e-06 +Organelle membrane contact site 11 19 2.6743225701412583 0.0074880388194549 6.817961165048544 16.400485436893202 0.815819301321945 0.3904411977369264 3.451940177462974 2.047328298639296 1.2919706717077657 0.3464717655445403 0.0220828366682075 1.0 0.0426903814680922 0.0090982869347887 2.9259500477213677e-05 +Vesicle membrane 70 295 2.6452912404877424 0.0081620632947754 59.03398058252427 252.66747572815535 0.5350285241159404 0.6113983912197217 17.512237349079548 29.567983380691818 1.3292572988488431 0.402876017449685 0.0129583322759491 0.0607131831213947 0.027669224886319 0.002484488880771 6.0411223047753845e-05 +Golgi cisterna membrane 12 20 2.6254869634208715 0.0086525122216305 6.233009708737864 17.101941747572816 0.7930989258143627 0.3092897028410761 3.2184356191878685 3.952300069740005 1.3504727992091758 0.2953094162507478 0.2261904642092787 1.0 0.3893086391655207 0.0344783823248686 2.8386728093734072e-05 +Intrinsic component of golgi membrane 8 14 2.575361580872281 0.0100135344502685 4.655339805825243 10.08495145631068 1.3178763872097854 0.2129685736028588 2.6046347098798024 1.9780511021437377 1.2704958978874823 0.2699640456705705 0.0057602811574553 0.1767085987036181 0.3284235846140172 0.0171039247471448 0.0001368435057556 +Late endosome membrane 9 43 2.5664247684761383 0.0102752912181995 8.400485436893204 35.220873786407765 -0.1907871949509251 0.3412955054288843 4.360825137615114 6.285848739997517 1.5677242851178623 0.3272837423268039 0.0051421613670933 0.4328077398558957 0.1076457490919223 0.0260354813107655 0.0325790146540505 +Specific granule membrane 7 20 2.482701435624984 0.0130390323057756 4.703883495145631 15.434466019417476 0.8701513897757543 0.3699585460258285 2.477017558764293 2.6655071934549124 0.9998631482292508 0.308737972868479 0.2071127419701942 0.2030241760524146 0.3716405295428093 0.0284946927562346 0.0084488258349492 +Rough endoplasmic reticulum 18 37 2.446160935456855 0.0144386534220128 8.516990291262136 34.51699029126213 0.6279779058801568 0.506302031213321 4.715930723848554 2.6644372563657086 1.002611026388539 0.3540125587222381 0.2453902245935762 1.0 0.4064849903072076 0.0411381952195085 0.0002489131742275 +Golgi stack 13 34 2.443142981081063 0.0145599675716634 9.67233009708738 31.25242718446602 0.7055900861920908 0.4265468940333196 4.557817503574521 5.847941213698429 1.2226912303929196 0.3463938041520717 0.5070563979241187 1.0 0.6060556355931213 0.0834480704023126 0.0024953089352164 +Golgi cisterna 13 26 2.41957534502458 0.0155386412984293 8.524271844660195 22.490291262135923 0.9086972174309816 0.318868202549777 4.2525712614684625 5.269200019661922 1.391079392561209 0.3149122340418913 0.360097882732204 1.0 0.4999495019072014 0.0294136582376105 0.0001674298904421 +Mib complex 7 10 2.4066849682280225 0.0160980496949836 4.669902912621359 10.016990291262136 0.8674199579421746 0.3102009046029466 2.3929035436504367 0.6011337749949848 1.2568635951567688 0.31203902687269 0.2026771210299193 1.0 0.1157837219692003 0.0368360647660487 7.565932780436378e-07 +Nucleoid 7 34 2.3921233155816157 0.0167512131287206 8.684466019417476 33.019417475728154 0.0681660648136321 0.5622694324694557 6.1060571118135485 2.5787804091332687 1.042554118474344 0.3307024216797329 0.0376968160993815 0.0166556908748058 0.0617507358035518 0.0815041572972921 0.0160691987109945 +Endosome 57 254 2.337504515044877 0.0194129664459654 49.68446601941748 210.85679611650485 0.3589512364806963 0.6263779709054735 15.417095902733692 27.960293924368397 1.2603534839168704 0.3964197633252465 0.0492427091067558 0.8343946647664408 0.1962179285380186 0.0358110421143596 0.0032002728480713 +Copii coated er to golgi transport vesicle 15 35 2.321438919355409 0.0202631670783195 10.810679611650484 32.4247572815534 0.9209697551014924 0.3949407296339237 5.01338814607213 3.9617918728777735 1.2509556054930144 0.3456813773327062 0.1090706215933892 0.2669704529063582 0.4705382708629992 0.0745088937074816 0.0045295872544912 +Exocytic vesicle 21 48 2.3090707285487846 0.0209396567550816 12.106796116504857 38.40533980582524 0.7408080162244459 0.4227017753873355 4.952517495270036 4.6543925000719675 1.3317240485888555 0.365166844745196 0.4179227395490513 1.0 0.7261578093414768 0.4046012619834337 0.0304901272357913 +Respiratory chain complex iv 4 9 2.2530675580306165 0.0242548896242753 3.754854368932039 9.74271844660194 0.8119042784517004 0.2590637228606872 2.032646352020888 1.0643473720992946 1.3870085883810457 0.2875864020654643 0.0378207561175528 0.0798652174269664 0.1566927560007753 0.0082779259052177 0.0012775061284849 +Pore complex 5 9 2.2455643235224594 0.0247319278108422 3.2111650485436893 8.830097087378642 1.029129610796519 0.2182996080526768 1.893158762220583 0.772882004264421 1.343874754683687 0.2717215815078918 0.0339972376759384 0.0027065615852008 0.0108829135912838 0.0070197321203344 9.39166481969502e-05 +Lumenal side of membrane 6 10 2.2442078294083694 0.0248190325246562 3.686893203883495 9.509708737864075 0.6270696996832885 0.3351332813726532 1.8490414883089543 0.9791034697552432 1.2332692274886168 0.3003490996154719 0.3185082358444843 1.0 1.0 0.4108142183097444 0.0004610339510786 +Golgi apparatus subcompartment 33 102 2.181382852774711 0.0291551108397898 23.898058252427184 88.56796116504854 0.6438651907142603 0.5157075238910589 9.044082768463602 13.85685287398648 1.2182273227220288 0.3801323692583779 0.0470071181606131 1.0 0.4767337492216527 0.0133051703969829 0.0030999136818236 +Tim23 mitochondrial import inner membrane translocase complex 3 6 2.134550942760047 0.0327977082546484 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.0007534171574726 0.0011140257717061 0.0045656876518621 8.959563589527918e-05 0.001326906313577 +Nuclear outer membrane 4 12 2.11229759291255 0.0346609321948812 2.7766990291262137 10.152912621359222 0.5537614638702467 0.4019518727724447 1.6732158376950717 1.011303235970013 1.01277391509177 0.2782181966835847 0.0459284510874455 0.0883440144706526 0.172526836456327 0.0805697230417203 0.0021347177486889 +Nadh dehydrogenase complex 14 27 2.111416600434478 0.034736519447198 7.419902912621359 23.609223300970875 0.690247022635013 0.3818090321561181 3.6908298840900926 3.1049932192976284 1.21822710313397 0.3228613418826432 0.0073675752544559 0.1880892294635792 0.0086239941031961 0.0040714376200731 4.181476323194264e-05 +Mitochondrial large ribosomal subunit 10 34 2.105548522042403 0.0352435882671886 8.633495145631068 29.555825242718445 -0.1481080091052014 0.5841135377138064 5.916009578876211 3.943692278182195 0.9731710590444376 0.3301980233297082 0.2325799851159216 0.2176901368863651 0.0887791366891333 0.1308343427210004 0.0128679597964932 +Respiratory chain complex iii 5 8 2.094917876870886 0.0361782934112833 2.5145631067961167 7.186893203883495 0.8648567981956616 0.2640480169416735 1.5224155414895728 0.9433070612984726 1.3007640218760226 0.2795290338624424 0.0203954716413504 0.0015706319822673 0.0063961411835862 0.0368360647660487 0.0026623648375823 +Presynaptic active zone 9 17 2.079613526005485 0.0375609953472999 4.803398058252427 14.970873786407768 0.3940654670567658 0.5114928405011878 2.7795522630987173 1.9568466345271975 0.9528581059832693 0.3105803383532612 1.0 1.0 1.0 0.6926728433665599 0.0289999376209375 +Endosome membrane 34 151 2.0780491490112407 0.0377048325406346 28.436893203883496 125.75485436893204 0.1968108610887141 0.5657595498250074 10.058247741499075 16.477863960688197 1.2734596099850304 0.3756178998455078 0.1248313726033393 0.5303398094048841 0.1507602304410294 0.1223061661798626 0.005453614363697 +Organellar ribosome 22 49 2.0606784330919226 0.0393337284974653 14.32766990291262 44.70873786407767 -0.3272491785902703 0.5734070752038083 8.382941034976346 5.414168876254706 1.0854266224547742 0.352666266494737 0.4032177401807827 0.3100025865648144 0.173725364232597 0.2954714349421587 0.0377489247785575 +Cis golgi network 6 15 2.0562488608219405 0.0397585348000351 5.446601941747573 14.91747572815534 1.304763677188147 0.2415633778835601 2.9087352716231463 3.2280604409731746 1.23405443481851 0.2890539664507128 0.029336552338356 0.1651718851687308 0.0519022265935445 0.0132790770586149 0.1158015503640465 +Blood microparticle 2 18 2.0373802342768204 0.0416119530465985 4.735436893203883 17.08252427184466 0.278306270999014 0.48728609275096 2.8336409309630577 1.4740425350178823 1.0421411126986748 0.31816279579515 0.0355040413058726 1.0 0.3284235846140172 0.077109656392341 0.3283671158988498 +Intrinsic component of nuclear inner membrane 4 7 2.021669181472463 0.0432105397362769 2.4344660194174756 6.461165048543689 0.7221555748366164 0.3746407047127702 1.5973511010756076 0.8763043548183138 1.0289148549650529 0.2984963891905157 0.1147834093059456 1.0 1.0 0.0108896879473024 4.869188728296504e-06 +Proton transporting two sector atpase complex 12 21 2.012479463698928 0.0441694193542336 7.116504854368932 22.25728155339806 1.0735578367707936 0.2848832687688338 3.2910616544032156 1.9833825153714253 1.32099194967518 0.2987458873835026 0.1161779578639089 0.0106226373895246 0.0404941431409166 0.1927267877862009 0.0009836297221044 +Proton transporting atp synthase complex 7 10 1.9997223829316748 0.0455302498474936 4.157766990291262 11.08495145631068 0.5328143574617974 0.3012358599713604 2.3610641964760792 1.138499586439592 1.3748267965121657 0.2836171984539964 0.256394918871775 0.0755969254036216 0.1486636480545473 0.3354743112563417 0.0009601967587914 +Lumenal side of endoplasmic reticulum membrane 5 8 1.9941309099158115 0.0461377500838942 3.0776699029126213 7.361650485436893 0.5475818769285827 0.3637002691484017 1.5990854205757892 0.8689828861838115 1.1522443815379428 0.2937666584254462 0.2692522225630656 1.0 1.0 0.3512730357569927 0.0012775061284849 +Azurophil granule 18 71 1.9674293145070467 0.0491337375482023 20.46359223300971 67.00485436893204 0.4795255752980384 0.3097891700346699 6.177875864944045 5.290582926033595 2.1760997104513735 0.3628132485163926 0.0145402225911423 1.0 0.2949514652379627 0.0059936587630553 2.0944440141766127e-06 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a9bd89025617508c30e2250896b6ff64d261ee4e --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 918, + "title": "Average number of proteins per term", + "value": 31.336601307189543 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..29036a5b89a03f1ade63c95362541fbbfe947e99 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..551e8e93b0750ca0884c69b4a4c4cc7e9aa44204 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,297 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Organelle subcompartment 0.6395491149536187 7.35843486945377 1.860790066352059e-13 1.7082144607654492e-10 1.7082144609111902e-10 404 Q9BQE5,Q9P0I2,Q9GZP9,Q14108,Q8N4V1,O15126,Q12893,Q8TCT9,P30519,Q8N0U8,Q16850,Q03518,Q15629,Q06136,P37268,O75477,Q99720,P67812,Q8TEM1,Q8N766,Q8N511,O95197,P24390,P43307,P49257,Q9Y282,P04843,O95772,P49755,P53365,P07099,Q9Y6B6,Q15392,O76062,Q14849,Q8NF37,P09601,Q9BRR6,Q8N2K0,Q9UEU0,Q5BJF2,Q5T9L3,O00461,P04062,Q969V3,Q9P2W9,P51648,Q86YN1,O60725,Q9BUN8,Q9NPR9,Q8TB61,Q9HC07,O75844,Q8N5M9,Q9NQC3,Q7Z2K6,O95070,Q15800,Q14739,Q9HD20,Q96N66,O95470,P38435,Q8NBN3,Q86XL3,Q15041,O60499,Q96A57,P35670,Q96G23,Q96KC8,Q9UKU0,Q5H8A4,P48449,Q5BJH7,Q8TCT8,Q53GQ0,Q10472,Q07065,Q96A33,O95864,P35613,Q9P035,P16615,Q9H3N1,O15127,O00264,Q92604,Q6Y1H2,Q8TBA6,O43292,Q15363,Q9BT22,Q9UM00,P16435,P57088,P46977,O14681,Q14534,P27544,Q86UE4,Q8N6G5,Q92643,Q8IV08,Q10713,Q15005,Q9Y5M8,O76024,P10321,Q12846,Q9H490,Q9H4A6,Q9UBM7,Q96RL7,Q6NUM9,P50402,P27824,Q12959,Q6UX53,Q70UQ0,Q9NZ01,Q9BU23,O15121,Q12770,Q6NTF9,Q9BTU6,Q9NUQ2,Q2TAA5,Q6IAN0,O00767,Q9UBU6,Q5VV42,Q12981,Q99735,Q9Y320,Q9Y4P3,O43852,Q86Y07,Q96PC5,Q9UL25,Q9NPA0,Q00765,P0CG08,P01889,O15260,P51571,Q8NBZ7,Q9UNL2,Q96S66,Q5J8M3,P04035,O75915,Q9NZ43,A1L0T0,O14678,P53367,Q96HY6,Q8NHH9,O14967,Q92581,Q8N5B7,Q9Y394,P51572,Q969X5,O14735,Q9BWS9,O14880,Q9NTJ5,O14656,Q9UKR5,P05067,O15269,Q03519,Q9Y3A6,Q9UBV2 176 +Endoplasmic reticulum 0.6211065295704469 7.235932305743015 4.623419091804118e-13 4.2443079053764533e-10 2.12215395313809e-10 518 Q9BQE5,Q9GZP9,Q9P0I2,Q14108,Q02878,P30533,Q8N4V1,Q9NRA0,Q9H6V9,P30519,Q8N0U8,Q8TCT9,Q16850,Q03518,Q15629,P56589,Q06136,P37268,O75477,Q99720,P67812,Q8TEM1,Q86YV9,Q8N511,O95197,P24390,Q8N766,P43307,P49257,Q9Y282,P46776,P04843,O95772,P49755,P07099,Q9Y6B6,Q15392,Q02818,O76062,Q14849,Q8NF37,P09601,Q9BRR6,P07237,Q8N2K0,Q5BJF2,Q9UEU0,Q5T9L3,Q9BVK6,O00255,P04062,P80303,Q9UMX5,Q969V3,Q9H488,Q9P2W9,P51648,Q13510,Q86YN1,O75352,O60725,Q9BUN8,Q8N2G8,Q9BSR8,Q8TB61,O75844,Q8N5M9,Q9NQC3,Q7Z2K6,P50454,O95070,Q15800,Q13641,O15173,Q14739,Q8TCJ2,Q9NXW2,Q9HD20,P27105,P30536,Q96N66,Q13724,O95470,P38435,P14314,Q86XL3,Q9Y3D6,Q9UGP8,Q99797,Q15041,Q86UL3,P27635,Q9UNK0,Q96A57,Q9H0U3,O15118,Q01105,Q13162,Q96G23,P61026,P61009,Q8IUH4,Q96KC8,Q9UKU0,Q5H8A4,Q969M3,P48449,Q5BJH7,Q8NFQ8,Q96LJ7,Q8TCT8,Q9NWM8,O75503,Q53GQ0,Q10472,Q07065,Q96A33,O95864,P35613,Q9P035,P16615,Q9H3N1,O00264,Q92604,Q6Y1H2,O43292,Q15363,Q9BT22,Q9UM00,P16435,P57088,P46977,O95881,O14681,Q14534,Q6ZXV5,P27544,Q5W0Z9,Q86UE4,Q92643,Q8IV08,P10619,Q15005,Q9UMX0,Q9Y5M8,Q9Y680,O76024,P10321,Q9H490,Q9UBM7,Q96RL7,Q6NUM9,P50402,P27824,Q12959,Q6UX53,Q92791,Q70UQ0,Q9NZ01,Q9BU23,Q14257,O15121,Q12770,Q9BTV4,Q6NTF9,Q9NUQ2,Q2TAA5,Q9BRK5,P48723,Q6IAN0,O00767,Q9UBU6,P83881,P36578,P05023,Q5VV42,Q12981,Q8TED1,Q99735,Q9Y320,Q9Y4P3,Q7L0J3,Q9Y3E0,O43852,O15258,Q86Y07,Q96PC5,Q92542,Q9UL25,Q9NPA0,Q00765,Q9NR31,P01889,O15260,P51571,Q9UNL2,Q96S66,Q5J8M3,P04035,O75915,P55327,Q9NZ43,A1L0T0,O14678,O43681,Q96HY6,Q9UQB8,Q8NHH9,O14967,Q92581,Q8N5B7,Q9Y394,P51572,Q969X5,O14735,P61916,O14880,Q9NTJ5,Q9H223,P52789,O14656,Q9UKR5,P05067,O15269,Q03519,Q9Y3A6,Q9UBV2 227 +Nuclear outer membrane endoplasmic reticulum membrane network 0.6690791852320287 6.728632507560504 1.712649915879431e-11 1.572212702231517e-08 5.2407090485910594e-09 330 Q9BQE5,Q9P0I2,Q9GZP9,Q14108,Q8N4V1,Q8TCT9,P30519,Q8N0U8,Q16850,Q03518,Q15629,Q06136,P37268,O75477,Q99720,P67812,Q8TEM1,Q8N766,Q8N511,O95197,P24390,P43307,P49257,Q9Y282,P04843,O95772,P49755,P07099,Q9Y6B6,Q15392,O76062,Q14849,Q8NF37,P09601,Q9BRR6,Q8N2K0,Q9UEU0,Q5BJF2,Q5T9L3,Q969V3,Q9P2W9,P51648,Q86YN1,O60725,Q9BUN8,Q8TB61,O75844,Q8N5M9,Q9NQC3,Q7Z2K6,O95070,Q15800,Q14739,Q9HD20,Q96N66,O95470,P38435,Q86XL3,Q15041,Q96G23,Q8IWB1,Q96KC8,Q9UKU0,Q5H8A4,P48449,Q5BJH7,Q8TCT8,Q53GQ0,Q10472,Q07065,Q96A33,O95864,P35613,Q9P035,P16615,Q9H3N1,O00264,Q92604,Q6Y1H2,O43292,Q15363,Q9BT22,Q9UM00,P16435,P57088,P46977,O14681,Q14534,P27544,Q86UE4,Q92643,Q8IV08,Q15005,Q9Y5M8,O76024,P10321,Q9H490,Q9UBM7,Q96RL7,Q6NUM9,P50402,P27824,Q12959,Q6UX53,Q70UQ0,Q9NZ01,Q9BU23,O15121,Q12770,Q6NTF9,Q9NUQ2,Q2TAA5,Q6IAN0,O00767,Q9UBU6,Q5VV42,Q12981,Q99735,Q9Y320,Q9Y4P3,O43852,Q86Y07,Q96PC5,Q9UL25,Q9NPA0,P01889,O15260,P51571,Q9UNL2,Q96S66,Q5J8M3,P04035,O75915,Q9NZ43,A1L0T0,O14678,Q96HY6,Q8NHH9,O14967,Q92581,Q8N5B7,Q9Y394,P51572,Q969X5,O14735,O14880,Q9NTJ5,O14656,Q9UKR5,O15269,Q03519,Q9Y3A6,Q9UBV2 153 +Organelle inner membrane 0.6860411998938274 6.3081190528477045 2.8244692553734707e-10 2.592862449832177e-07 6.482156964032117e-08 248 P14406,Q96GC5,Q8WWC4,O60830,Q03252,Q99595,P53007,Q69YU5,Q9NRA0,Q9NVH1,Q9H061,Q53H12,O75964,Q99720,O14949,Q96CU9,O43676,P82933,P82663,Q567V2,Q9UDW1,Q70HW3,Q9UDX5,Q96BW9,O76062,Q13505,O75880,Q9Y2R0,O43772,Q5T653,Q9H1E5,Q8NBN7,Q86Y39,Q9BSK2,Q8IXM6,P03886,Q02978,O43819,Q96TA2,Q7Z7H8,Q9BYN8,Q9Y619,Q9H2D1,O75844,P12532,Q9UBX3,Q14739,Q9NX14,Q9Y6C9,P40939,Q9Y5J9,P36542,Q9HC21,Q86VD7,Q9UJZ1,Q05932,P13073,P22830,O43674,P56134,O14925,Q9UG56,Q9BYD2,Q9Y6M9,Q6KCM7,P49406,P14927,P21912,Q5XKP0,Q9Y6N1,Q14728,Q13084,P62995,Q5SNT2,Q15070,P00403,Q13423,Q9P0J0,Q9Y5J6,P12236,Q6UXV4,Q16891,Q10713,Q9NVI7,Q9BUB7,P23786,Q6P4A7,Q9BYD1,P50402,P08574,Q16134,O96008,Q96ER9,O95202,O95168,Q9BTV4,P51970,Q9H3K2,O96000,O95563,Q9UH99,P24539,P49748,Q99623,P53701,O60313,Q96IX5,Q9Y375,Q9NPL8,Q5JTV8,Q8NI60,O43615,Q9NWU5,Q9Y512,Q9NX63,Q6NUK1,P15954,P12235,P05141,Q9BRJ2,Q5T9A4,O75431,Q8N183,Q96AQ8,Q96NB2,P56385,P20700,O94901,Q6DKK2,P82930,O75947,Q8TBP6,O75380,Q9UJS0,Q9HD33,P22695,P06576 137 +Intrinsic component of organelle membrane 0.741164692457363 6.178099003577597 6.487802820115687e-10 5.955801226399089e-07 1.0818302859765805e-07 149 Q9P0I2,Q9GZP9,O60830,Q99595,Q8N4V1,O15126,Q9NVH1,Q8TCT9,Q53H12,Q03518,Q15629,P56589,Q8N766,Q8WVX9,Q9Y282,O76062,Q13505,Q9Y2R0,Q5T9L3,Q86YN1,Q9BUN8,Q8TB61,O75844,Q9NQC3,O95070,Q14739,O95470,Q86XL3,Q15041,Q9HC21,O60499,O15118,Q5H8A4,Q5BJH7,O14925,Q9UG56,Q8TCT8,Q5XKP0,Q96A33,Q9P035,Q5SNT2,Q6Y1H2,O43292,Q15070,Q9UM00,P57088,P42892,Q6UXV4,Q5W0Z9,Q8N6G5,Q92643,Q9Y287,Q16891,P13473,O76024,Q9BUB7,P10321,Q9H490,Q9UBM7,Q6P4A7,P27824,Q16134,O96008,Q8TB36,Q96ER9,Q9NZ01,Q9BTV4,Q6NTF9,Q9H3K2,O95563,O00767,Q9UH99,O43808,O43505,Q12981,Q9Y4P3,Q7L0J3,O15258,Q9NPA0,P01889,Q9Y512,Q9NX63,Q5J8M3,P12235,O75431,Q96AQ8,Q96NB2,Q86Y82,O94901,P51572,Q969X5,Q03519 92 +Mitochondrial envelope 0.6334318569735139 6.164496274602712 7.070786172853465e-10 6.490979611512572e-07 1.0818302859765805e-07 321 P14406,Q96GC5,Q8WWC4,O60830,Q9NS69,O43169,Q99595,P53007,Q69YU5,P21796,Q9NRA0,Q9NVH1,Q9H061,P45880,Q53H12,O75964,O14949,Q8WY22,Q96CU9,Q96TC7,O43676,P82933,Q8N4H5,P82663,Q567V2,Q9UDW1,O95140,Q70HW3,Q9UDX5,Q96BW9,Q13505,P09601,O75880,Q9Y2R0,Q96A26,O43772,Q5T653,Q8NBN7,Q86Y39,Q9BSK2,P03886,Q02978,O43819,Q96TA2,Q7Z7H8,Q8N2A8,Q9BYN8,Q9Y619,Q9H2D1,P12532,Q99536,Q9UBX3,Q9NX14,Q9Y6C9,P30536,P40939,Q8WWI5,Q9Y5J9,Q9Y3D6,Q9NZJ7,P36542,Q9HC21,Q86VD7,Q9UJZ1,Q05932,P13073,P22830,Q9UKU0,O43674,O14925,P56134,Q9UG56,Q9BYD2,Q9Y6M9,Q6KCM7,P49406,P21912,Q5XKP0,Q13084,Q9NQZ5,Q9Y277,O00264,Q15070,Q9P0S9,P00403,Q13423,Q9P0J0,Q9Y5J6,P12236,Q6UXV4,Q9BXK5,Q16891,Q10713,Q9NVI7,Q07820,Q9BUB7,Q9H4A6,P23786,Q6P4A7,Q96RL7,Q9BYD1,P08574,Q16134,O96008,Q8TB36,Q96ER9,O95202,O15121,O95168,P51970,Q9HCL2,Q9NUQ2,Q9H3K2,O96000,O95563,P24539,P49748,Q12981,Q9H078,Q9Y320,Q99623,P53701,O60313,Q86Y07,Q96IX5,Q9Y375,Q9NPL8,Q8NI60,O43615,Q9NWU5,Q9Y512,Q9NX63,Q6NUK1,P15954,P12235,P05141,Q9BRJ2,Q5T9A4,O75431,Q8N183,Q96AQ8,Q96I36,Q96NB2,P56385,Q6DKK2,P82930,O75947,Q8TBP6,O75380,Q9UJS0,Q9HD33,P22695,P52789,Q8WWV3,P06576 155 +Envelope 0.5483698498091073 6.016497170043612 1.782316127105993e-09 1.6361648685401857e-06 2.337380293716145e-07 512 P14406,Q96GC5,Q8WWC4,O60830,Q9NS69,O43169,Q99595,Q03252,P53007,Q69YU5,P21796,Q9NRA0,Q9NVH1,Q9H061,P45880,Q5XPI4,Q53H12,O75964,Q99720,Q8TEM1,O14949,Q8WY22,Q96CU9,Q96TC7,O43676,P82933,Q8N4H5,P82663,Q567V2,Q9UDW1,O95140,Q70HW3,Q9UDX5,Q96BW9,O76062,Q7Z3B4,Q13505,P09601,O75880,Q9Y2R0,Q5BJF2,Q96A26,O43772,Q9H1E5,Q5T653,P80303,Q8NBN7,Q86Y39,Q9BSK2,Q8IXM6,P03886,Q02978,O43819,Q96TA2,Q8N2G8,Q7Z7H8,Q8N2A8,Q9BTX1,Q9BYN8,Q9Y619,Q5JVF3,Q9H2D1,O75844,Q99536,P12532,Q9NQC3,Q9UBX3,O15173,Q14739,Q9Y6C9,Q9NXW2,Q9NX14,P30536,P40939,Q8WWI5,Q9Y5J9,Q9NZJ7,Q9HC21,Q86VD7,O15118,P13073,Q8IWB1,P22830,Q96KC8,Q9UKU0,O14925,Q9UG56,Q9Y6M9,Q6KCM7,P21912,P41208,Q5XKP0,Q14728,Q13084,Q9P035,Q5SNT2,Q9NQZ5,Q9Y277,O00264,Q15070,Q9P0S9,P00403,P42167,Q13423,P57088,Q9P0J0,Q9Y5J6,O14681,P12236,Q6UXV4,P02545,Q86UE4,Q9BXK5,Q16891,Q10713,Q9NVI7,Q07820,Q9BUB7,Q9H4A6,Q9UBM7,P23786,Q6P4A7,Q96RL7,Q9BYD1,Q6NUM9,P50402,P08574,Q16134,O96008,Q8TB36,Q96ER9,O95202,O15121,O95168,Q9BTV4,P51970,Q9HCL2,Q9NUQ2,Q9H3K2,O96000,O95563,Q9UH99,P24539,P49748,Q12981,Q99735,Q9H078,Q9Y320,Q99623,P53701,O60313,Q86Y07,Q96IX5,Q9Y375,Q9NPL8,Q5JTV8,Q8NI60,O43615,Q9NWU5,Q9Y512,Q96S66,Q9NX63,Q6NUK1,P15954,P12235,P05141,Q9BRJ2,Q5T9A4,O75431,Q8N183,Q96AQ8,Q96I36,Q96NB2,P56385,P20700,O94901,Q6DKK2,P82930,O75947,Q8TBP6,O15504,O75380,Q9UJS0,Q9HD33,O14880,P22695,P52789,O14656,Q8WWV3,P06576,P05067 191 +Mitochondrial protein containing complex 0.6089275228251066 4.959025452412706 7.084768559437946e-07 0.0006501705316291 8.129771921966518e-05 160 Q9Y5J9,P14406,Q96GC5,Q16891,O60830,Q9NS69,Q99595,P36542,O00411,P21796,Q9NVH1,Q9NWU5,Q9Y512,Q53H12,O75964,P13073,Q9NX63,P15954,P12235,O14949,O43674,Q9BYD1,P05141,Q96CU9,P56134,O14925,O43676,P82933,Q9BYD2,Q8N4H5,P12694,Q9Y6M9,Q567V2,Q9UDW1,P49406,P08574,O96008,O75431,P21912,Q5XKP0,O95168,Q13505,Q13084,P51970,P56385,Q9BRJ2,O96000,Q5T653,O14874,P82930,Q86Y39,O75947,P03886,O75380,P24539,Q9HD33,Q7Z7H8,P00403,Q9BYN8,P06576,P22695,Q9P0J0,Q9Y5J6,P12236,Q99623,Q9NX14,Q6UXV4,Q96IX5,P40939,Q9Y375 70 +Membrane protein complex 0.531842648735909 4.701554934408806 2.581877804219701e-06 0.0023673602563174 0.0002633515360305 318 Q9P0I2,P14406,Q9GZP9,O60830,Q9NS69,Q99595,Q8N4V1,P21796,Q9NVH1,P45880,Q8TCT9,Q53H12,O75964,Q03518,P67812,O14949,Q8N766,Q8N511,Q96CU9,O43676,Q8N4H5,P04843,Q9UDW1,P49755,Q9Y6B6,Q13505,Q8N2K0,Q9C0H2,Q9UEU0,Q86Y39,Q9UBI6,Q92796,Q9P2W9,P03886,Q9BUN8,P09429,Q8TCJ2,Q9NX14,Q9UGP8,P36896,Q15041,P36542,O60499,Q14254,Q9UNK0,Q9H0U3,P13073,P61009,O43674,Q9P253,O14925,P56134,Q9Y6M9,Q53GQ0,P36543,P14927,P08195,P21912,Q5XKP0,P51798,O75955,Q15388,Q96CS3,Q9Y277,Q96S52,Q9H9H4,O43292,P63218,Q16795,P00403,P61803,P46977,Q9P0J0,Q9Y5J6,Q9H270,Q9Y276,Q8IWA4,P12236,Q6UXV4,P04844,Q92643,Q16891,Q15005,Q9Y5M8,Q93050,P10321,Q12846,Q9H490,Q12959,P08574,O96008,Q96ER9,O95168,P51970,Q6NTF9,O96000,O15400,Q9UH99,Q9UBU6,P24539,P05023,Q12981,Q99623,Q5SQN1,Q96IX5,Q9Y375,Q92542,Q9NPA0,Q9NR31,P01889,P51571,Q9Y512,Q96S66,Q9NX63,Q5J8M3,P15954,P12235,P05141,Q9NZ43,O14678,O75431,Q9UBC2,Q86Y82,Q4KMQ2,P56385,O94901,O75947,O75380,Q9H0R1,P41440,P22695,P06576,O15269,Q03519,Q9UBV2 135 +Intrinsic component of endoplasmic reticulum membrane 0.7670387903577072 4.507229426851848 6.567960431747011e-06 0.0060112670764935 0.0006029387676344 60 Q9P0I2,Q9GZP9,Q86XL3,Q03519,Q15041,Q9NPA0,Q8N4V1,P01889,Q8TCT9,O76024,P10321,Q03518,Q15629,Q5J8M3,Q9H490,Q9UBM7,Q5H8A4,P27824,Q8TCT8,Q9Y282,Q9NZ01,O76062,Q96A33,Q6NTF9,Q9P035,P51572,Q6Y1H2,O00767,O43292,Q969X5,Q86YN1,Q9UM00,Q9BUN8,P57088,Q8TB61,Q12981,O75844,Q9NQC3,Q9Y4P3,Q92643,O95470 41 +Golgi membrane 0.5852750895324059 4.450375631116191 8.572022404118584e-06 0.0078382695858544 0.0007153742333619 143 Q8NBN3,Q14108,Q10713,Q9UL25,Q16739,P0CG08,Q8N4V1,O60499,P01889,O15260,P35670,P10321,Q96S66,Q8TBQ9,Q8IUH4,Q9H4A6,Q5BJH7,Q8NCH0,O95197,P24390,Q9Y282,P53367,Q10472,Q15392,Q86Y82,Q12770,Q8NF37,Q6NTF9,P35613,Q5T9L3,O00461,Q9H7Z7,P51572,Q9P2W9,Q8TBA6,Q969X5,Q15363,Q8IZA0,Q9UM00,Q8N4A0,O43505,Q8TB61,Q9NTJ5,Q9HC07,Q7LGA3,O95070,Q9Y3E0,O15258,Q5W0Z9,Q8N6G5,Q8IV08,Q9Y287 52 +Inner mitochondrial membrane protein complex 0.6931316268548322 4.403591022019459 1.0647358078319512e-05 0.0097267132758121 0.0008145228929915 77 P14406,Q16891,O60830,Q99595,Q9NVH1,Q9Y512,Q53H12,O75964,P13073,Q9NX63,P15954,O14949,O14925,O43676,Q9Y6M9,P08574,O75431,Q9UDW1,P21912,Q5XKP0,O95168,Q13505,P51970,P56385,O96000,Q86Y39,O75947,P03886,O75380,P24539,P00403,P22695,Q9P0J0,Q9Y5J6,P12236,Q99623,Q6UXV4,P06576,Q96IX5,Q9Y375 40 +Outer membrane 0.6116688063765907 4.176382250992303 2.9618194722358385e-05 0.0268235874956767 0.0015105279308403 95 Q16891,Q9NZJ7,Q9NS69,O43169,P21796,Q9NVH1,P45880,Q07820,Q9Y512,Q53H12,Q9NX63,Q8IWB1,Q9UBM7,Q9UKU0,Q99720,Q96RL7,Q8WY22,Q6NUM9,P50402,Q96TC7,Q8N4H5,O75431,O96008,Q8TB36,Q5XKP0,Q13505,P09601,Q9HCL2,Q9NUQ2,Q9NQZ5,Q9Y277,O00264,Q8N2A8,Q99536,P52789,Q99623,Q8WWV3,Q6UXV4,Q9Y6C9,O60313,P30536 41 +Lysosomal lumen 0.7729925489174096 4.110328053965094 3.9509739762078055e-05 0.035620758441557 0.0016762114378057 35 Q9NZJ7,Q14108,P10619,P13473,P16278,Q9UMR5,O43681,P50897,P11117,Q9UM22,P04062,Q8NHP8,P10253,Q13510,Q9BWS9,P54802,P07602,P17900,O14773,P38435,Q8IV08 21 +Intrinsic component of mitochondrial inner membrane 0.7714623434754846 4.013919368954345 5.9718753859794305e-05 0.0533477382326771 0.002030437631233 34 Q16891,O60830,Q99595,Q9HC21,Q9NVH1,Q9Y512,Q53H12,Q9NX63,Q6P4A7,O14925,Q9UG56,O75431,Q16134,Q96AQ8,Q96ER9,Q96NB2,Q5XKP0,Q13505,O75880,Q9Y2R0,Q9H3K2,O95563,Q15070,Q6UXV4 24 +Intrinsic component of plasma membrane 0.5946716065995755 3.957403296518724 7.57689457300259e-05 0.0671944628973906 0.0021971617589889 92 Q92542,O43657,Q99797,P36896,Q15758,P01889,Q9UNK0,Q9H2J7,P35670,Q9H0U3,O15118,P10321,P33527,Q8WTV0,P36551,A0FGR8,P12235,P04439,P05141,P11279,O96005,O60637,P27824,Q08722,O76062,O15121,Q99805,O15031,P30825,O95864,Q8N2K0,P35613,Q9BTU6,P16615,O00264,P51572,Q92796,Q02978,Q9UJS0,Q96QD8,P53985,P05023,P41440,P05067,P10586,Q13641,Q9Y639,P51790,P20020,P27105,Q9UIQ6 51 +Golgi apparatus 0.4662167302376597 3.952060071928169 7.74812831016991e-05 0.0686597242340747 0.0021971617589889 353 Q14108,P30533,Q8N4V1,O15126,Q12893,O95197,P24390,P22466,P49257,Q9Y282,P49755,P53365,Q9Y6B6,P50897,Q15392,Q02818,Q8NF37,Q9UEU0,Q9BVK6,Q5T9L3,O00461,P04062,P80303,Q5VW38,Q9P2W9,Q8N2A8,Q9NPR9,Q8TB61,Q9HC07,O95070,O14773,Q8NBN3,Q16739,O60499,Q96A57,P35670,O15118,Q8IUH4,Q5BJH7,Q8NCH0,O75503,Q10472,Q99805,Q9NX40,P35613,Q9H7Z7,O15127,P46934,Q8TBA6,Q15363,Q8IZA0,Q9UM00,Q8N4A0,Q92520,O14681,Q5W0Z9,Q8N6G5,Q8IV08,Q9Y287,Q10713,Q93050,Q9H8H2,P10321,Q12846,P16278,Q9H4A6,Q96RL7,Q12959,Q12770,Q9BTV4,Q6NTF9,Q9BTU6,Q9BRK5,Q7RTS9,Q96M27,P05023,O43505,Q7LGA3,Q9Y3E0,O43852,O15258,Q92542,Q9UL25,Q9NR31,P0CG08,P01889,O15260,Q8NBZ7,Q96S66,Q8TBQ9,Q92544,P53367,Q9UQB8,Q86Y82,P51572,Q969X5,O14735,Q9BWS9,Q9NTJ5,Q96SU4,P51790,P05067,Q9Y3A6 103 +Intrinsic component of mitochondrial membrane 0.6951052730564871 3.801358024572396 0.0001439051883664 0.1237593131682811 0.0033026240730109 51 Q9Y3D6,Q16891,O60830,Q99595,Q9HC21,Q9NVH1,Q9Y512,Q9BUB7,Q53H12,Q9NX63,P12235,Q6P4A7,O14925,Q9UG56,O75431,Q16134,O96008,O95140,Q96AQ8,Q8TB36,Q96ER9,Q96NB2,Q5XKP0,Q9Y6N1,Q13505,O75880,Q9Y2R0,Q9H3K2,Q15388,O95563,Q15070,O43819,Q9H9B4,Q6UXV4 34 +Vacuole 0.4908472107533398 3.741854613175428 0.0001826671886138 0.1543957315511628 0.0040899629060362 239 Q92542,Q9NZJ7,Q14108,P10619,Q9UMX0,P13473,Q93050,O15260,Q9NRA0,Q96A57,Q969Q5,O15118,Q12846,P16278,Q8WTV0,Q96RL7,Q8N511,Q9P253,Q9UMR5,P11279,Q8NCG7,Q9NZ43,Q8TCT8,O14678,Q8NCC3,O75503,O43681,O95772,Q15165,P50897,Q07065,Q9UHG3,P42785,Q14849,Q9NX40,Q8NF37,Q9BTU6,O75955,Q5BJF2,Q9UM22,P11117,Q9H7Z7,P04062,O15400,Q8IV08,Q8NHP8,P10253,Q13510,Q9BWS9,P54802,Q9H0R1,P61916,P07602,P42892,Q9HC07,Q8NHS3,Q99536,P17900,O14773,P27105,P00813,P38435 62 +Vacuolar membrane 0.5173787298155936 3.60030081614407 0.0003178492396267 0.253105984215478 0.0067857116738919 137 Q92542,Q9NZJ7,Q14108,P10619,P13473,Q93050,O15260,Q9NRA0,O15118,Q8WTV0,Q96RL7,Q8N511,Q9P253,P11279,Q8NCG7,Q8TCT8,O14678,O75503,O95772,Q07065,P42785,Q14849,Q8NF37,Q9BTU6,O75955,P11117,P04062,O15400,P10253,Q9H0R1,P41440,P07602,P42892,Q9HC07,Q8NHS3,P27105,Q8IV08 37 +Mitochondrion 0.4307837769562695 3.585836383932519 0.0003359995825142 0.2654516419583792 0.0070101731079118 652 P14406,Q96GC5,Q8WWC4,O60830,Q9NS69,O43169,Q99595,P53007,P28288,Q69YU5,P21796,Q9NRA0,Q9NVH1,Q9H061,P45880,Q53H12,O75964,O14949,Q8WY22,Q96CU9,Q96TC7,O43676,Q9H773,P82933,Q8N4H5,P82663,P12694,Q567V2,Q9UDW1,O95140,Q70HW3,Q15165,Q9UDX5,Q9UL15,Q96BW9,Q5TC12,Q14849,Q13505,P09601,O75880,Q9Y2R0,Q96A26,O43772,Q5T653,Q8NBN7,Q86Y39,Q9UMX5,Q9BSK2,P03886,Q16740,Q02978,O43819,Q96TA2,Q7Z7H8,Q8N2A8,Q9NR77,Q9BXW7,Q9BYN8,Q3SXM5,Q9H2D1,Q99536,Q9NPH0,Q9UBX3,Q9Y6C9,P27105,P30536,P40939,Q8IXJ6,Q9NZJ7,Q9HC21,Q86VD7,P35670,P13073,P22830,Q9UKU0,O14925,Q9UG56,Q9Y6M9,Q6KCM7,Q9HC38,P21912,O00116,P00374,Q5XKP0,Q13084,P35613,Q9NQZ5,Q9H7Z7,Q9Y277,O14874,O00264,O43292,Q15070,Q9P0S9,P16435,P00403,Q13423,Q9UIJ7,Q9P0J0,Q9Y5J6,P12236,Q13011,Q6UXV4,Q9BXK5,Q16891,Q10713,Q9NVI7,Q07820,Q9BUB7,Q9H4A6,P23786,Q6P4A7,Q96RL7,Q9BYD1,P08574,Q16134,O96008,Q8TB36,Q96ER9,O95202,O15121,O95168,P51970,Q9BTU6,Q9HCL2,Q9NUQ2,Q9H3K2,O96000,O95563,P48723,Q9NUJ1,Q9BWD1,O95900,P24539,P49748,Q12981,Q9H078,Q9Y320,Q99623,P53701,O60313,Q86Y07,Q96IX5,Q9Y375,Q9NPL8,Q92542,Q8NI60,O43615,Q9NWU5,Q9Y512,Q9NX63,Q6NUK1,P15954,P12235,P05141,Q9BRJ2,Q5T9A4,O75431,Q8N183,Q96AQ8,Q96I36,Q96NB2,Q9NWS8,Q92581,P56385,Q6DKK2,P82930,P51572,O75947,Q8TBP6,O75380,Q9UJS0,Q9HD33,Q96T60,P22695,Q8TB37,P52789,Q8WWV3,P14735,P06576,P04179 181 +Respirasome 0.6601434654083749 3.451512072010818 0.0005574548183373 0.4006360163314972 0.0111248592007324 45 P14406,P13073,P15954,O14949,O43676,P08574,Q9Y6M9,Q9UDW1,P21912,O95168,P51970,O96000,Q6DKK2,Q86Y39,P03886,O75380,P00403,Q13423,Q9P0J0,Q9Y375 20 +Endoplasmic reticulum protein containing complex 0.612621424704973 3.433874287611535 0.0005950200849671 0.4209642222120176 0.011621881659571 67 Q9P0I2,Q9GZP9,Q9UGP8,P14314,Q15041,Q9NPA0,Q15005,Q9Y5M8,Q8N4V1,P51571,Q9H0U3,Q8TCT9,Q03518,P61009,Q5J8M3,Q9H490,Q15006,P67812,Q8N766,O43681,Q53GQ0,P04843,Q9Y4L1,P07237,Q6NTF9,Q96CS3,Q96S52,O43292,Q9UBU6,Q9BUN8,P13674,P61803,P46977,Q8TCJ2,P04844,O15269,Q92643,Q03519,Q9UBV2 39 +Nuclear inner membrane 0.74760383155937 3.146540161641718 0.0016521456986184 0.7808335983294419 0.0252778291888629 23 Q5JTV8,P50402,P20700,O94901,Q5SNT2,Q9H1E5,O75844,Q99720,Q8IXM6,Q9UH99,Q14739,O76062,Q9BTV4,Q14728 14 +Vacuolar lumen 0.5798618657987211 3.124533663942279 0.001780871428809 0.8053004002156531 0.0268006552728961 66 Q9NZJ7,Q14108,P10619,P13473,P16278,Q9UMR5,O43681,P50897,P11117,Q9UM22,Q9H7Z7,P04062,Q8NHP8,P10253,Q13510,Q9BWS9,P54802,P07602,Q99536,P17900,O14773,P38435,Q8IV08 23 +Azurophil granule membrane 0.7209980034458415 2.988278096597795 0.0028055414700618 0.9241582737023044 0.0402853329973624 23 Q92542,Q8NF37,Q9NZJ7,P11279,P27105,P07602,P13473,O15260,Q07065,P42785 10 +Endoplasmic reticulum golgi intermediate compartment 0.5882374577451518 2.94789191335497 0.0031994891033086 0.9472314390657632 0.0451866307205751 50 P30533,O15260,Q03518,Q5BJH7,Q8N511,P24390,P49257,Q9Y282,P49755,Q10472,Q02818,P07237,Q9BVK6,P80303,P51572,Q969X5,Q15363,P09429,O95070,O15258,Q03519,Q9Y3A6 22 +Late endosome 0.5259650935219334 2.931147231828824 0.0033771268270319 0.9551956090220092 0.0469727640487171 79 Q9NZJ7,Q14108,P13473,Q96A57,P35670,O15118,Q9P253,P11279,Q8TCT8,O95772,Q14849,Q9BRK5,O15400,Q9BWS9,Q9BUN8,Q9H0R1,P07602,Q9HC07,Q96SU4,Q9BXW6,P51790,Q8IV08 22 +Endoplasmic reticulum golgi intermediate compartment membrane 0.6663623276768859 2.912846372539323 0.0035815075359635 0.9628846889154448 0.0490719987763362 28 Q5BJH7,Q8N511,P24390,P49257,Q9Y282,O15260,P51572,P49755,O95070,Q10472,Q969X5,Q03518,Q15363,Q03519,Q9Y3A6 15 +Transporter complex 0.5564297139473646 2.8757839862178876 0.0040302542020915 0.975455045459686 0.0528539051074295 64 Q9Y5J9,Q96S66,O14949,O43674,Q96CU9,O43676,P08574,O14678,Q9Y6M9,Q9UDW1,P14927,Q96ER9,O95168,P51970,Q4KMQ2,Q8N2K0,Q9C0H2,P51798,O75381,O96000,Q86Y39,Q92796,P03886,O75380,Q16795,P05023,P22695,Q9P0J0,Q9Y5J6,Q9Y276,Q9NX14,Q9Y375 32 +Secretory granule membrane 0.526367768535155 2.8042602610481273 0.0050432177475701 0.9903556933148012 0.0625595892991669 74 Q92542,Q9NZJ7,P01889,Q93050,P13473,O15260,Q969Q5,P30519,P10321,P11279,Q5T9A4,Q08722,Q07065,O15121,P42785,Q8NF37,Q4KMQ2,P35613,O00264,Q15363,P07602,P27105 22 +Microbody membrane 0.6331825054705931 2.7999484023590475 0.0051110775571214 0.9909410378657616 0.0625595892991669 30 Q9Y3D6,P51659,P28288,Q5T8D3,P56589,Q9UKU0,P04035,Q8WVX9,Q7Z434,O14678,Q8TB36,Q96K12,Q9BY49,O00116,P40855,O75381,Q6IAN0,P51648,Q9NR77,O43808 20 +Lipid droplet 0.602261097494764 2.764338075561857 0.0057038408737017 0.994758334377691 0.0685865565430206 33 Q8NF37,Q9H6V9,Q01105,O43760,Q07065,Q99720,Q96RL7,P48449 8 +Outer mitochondrial membrane protein complex 0.767812321310997 2.761542498402524 0.0057529028908633 0.9949904760194036 0.0685865565430206 16 Q16891,Q9NS69,Q8N4H5,O75431,O96008,Q9Y512,Q6UXV4,Q9NX63,Q5XKP0,Q13505 10 +Compact myelin 0.964596796853048 2.7224689571739087 0.0064796120714023 0.9974397204345652 0.0743535485193419 2 Q9NR77 1 +Cytochrome complex 0.7723520911783844 2.7121034626453464 0.0066857721169419 0.9978838307993346 0.0757720839920092 15 P14406,P08574,Q9UDW1,P13073,P15954,O14949,P00403 7 +Oxidoreductase complex 0.5351947932496357 2.6996616611945328 0.006941002441078 0.9983285379932249 0.0777053687915815 65 O43169,O14949,O43674,Q96CU9,O43676,P08574,Q9Y6M9,P12694,Q9UDW1,P14927,P21912,O95168,P51970,P07237,O43837,O96000,O14874,Q86Y39,P03886,O75380,Q16795,P13674,P22695,Q9P0J0,Q9Y276,Q9NX14,O75251,Q9Y375 28 +Organelle membrane contact site 0.7075433131616299 2.6743225701412583 0.0074880388194549 0.9989920989735206 0.0828195136898749 19 P27824,Q9NTJ5,Q9Y320,O95772,O96008,P51572,Q9BXW6,Q96S66,Q5XKP0,Q96N66,Q14849 11 +Vesicle membrane 0.410809325283079 2.6452912404877424 0.0081620632947754 0.9994597722595988 0.0861238402828027 295 Q92542,O43924,Q14108,Q9NZJ7,Q9UL25,Q9NR31,Q8N4V1,O60499,O15126,P13473,Q93050,Q969Q5,P01889,O15118,P30519,O76024,P10321,Q12846,Q03518,Q8IUH4,P55899,Q8WTV0,Q96RL7,Q86YV9,Q8N511,Q9P253,P24390,P11279,Q8TCT8,P49257,Q5T9A4,O95772,P49755,Q08722,O43760,Q86Y82,Q07065,O15121,Q15057,P42785,Q14849,Q99805,Q14728,Q8NF37,Q12770,P35613,Q92581,Q4KMQ2,Q5T9L3,O00461,O15260,O15127,O15400,O00264,Q9UH99,P10253,Q15363,Q9H0R1,P07602,Q9H223,P42892,Q9HC07,Q96SU4,O14656,Q7L0J3,P51790,P27105,Q03519,Q8IV08,Q9Y287 70 +Golgi cisterna membrane 0.6903609012929318 2.6254869634208715 0.0086525122216305 0.9996569276548488 0.0892472608927735 20 Q8NBN3,Q9UL25,Q10713,P0CG08,O00461,Q8N6G5,Q12893,P51572,Q8NBZ7,Q10472,Q15363,Q9H4A6 12 +Intrinsic component of golgi membrane 0.7589297641881093 2.575361580872281 0.0100135344502685 0.9999028018156224 0.093800251279046 14 Q5BJH7,O43505,Q8TB61,Q9Y282,O95070,O15258,Q5W0Z9,Q8N6G5 8 +Late endosome membrane 0.5510622570146683 2.5664247684761383 0.0102752912181995 0.999923751578971 0.0952799731142143 43 Q9P253,Q14108,Q8TCT8,Q9HC07,P13473,O95772,O15118,Q14849,Q8IV08 9 +Autolysosome 0.9185164372014608 2.5254825415870568 0.0115539522067251 0.9999767284245972 0.1019858473632087 2 P13473 1 +Secondary lysosome 0.9185164372014608 2.5254825415870568 0.0115539522067251 0.9999767284245972 0.1019858473632087 2 P13473 1 +Specific granule membrane 0.6663569905769463 2.4827014356249837 0.0130390323057756 0.9999941469884076 0.1118675855766545 20 Q4KMQ2,P27105,O00264,Q08722,P30519,Q07065,O15121 7 +Rough endoplasmic reticulum 0.5418003176539475 2.446160935456855 0.0144386534220128 0.9999984092499355 0.1204148669440274 37 Q5VV42,Q9UGP8,P62266,Q15041,Q02878,P27824,Q9Y5M8,P30533,Q5BJF2,P51571,P04843,P05067,Q8TCT9,P04844,Q9UQB8,Q07065,Q96A33,P36578 18 +Golgi stack 0.5512222557516083 2.443142981081063 0.0145599675716634 0.9999985792274668 0.1204148669440274 34 Q8NBN3,Q9UL25,Q10713,P0CG08,O00461,Q8N6G5,Q12893,P51572,Q8NBZ7,Q10472,Q8TBA6,Q15363,Q9H4A6 13 +Golgi cisterna 0.6074366900237147 2.41957534502458 0.0155386412984293 0.9999994293327642 0.1273613634996259 26 Q8NBN3,Q9UL25,Q10713,P0CG08,O00461,Q8N6G5,Q12893,P51572,Q8NBZ7,Q10472,Q8TBA6,Q15363,Q9H4A6 13 +Mib complex 0.7948476410044049 2.4066849682280225 0.0160980496949836 0.9999996613336256 0.1307788461946457 10 Q16891,O75431,Q9Y512,Q6UXV4,Q9NX63,Q5XKP0,Q13505 7 +Nucleoid 0.5447251567609739 2.3921233155816153 0.0167512131287206 0.9999998159148004 0.1337183795840482 34 P05141,P49748,P21796,Q9NVI7,P45880,P06576,P40939 7 +Endosome 0.3983586362092809 2.337504515044877 0.0194129664459654 0.9999999847144097 0.1524919706273969 254 Q92542,Q9GZP9,Q9NZJ7,Q14108,Q9UL25,P30533,Q8N4V1,P13473,Q93050,P01889,Q96A57,P35670,Q969Q5,O15118,P10321,Q12846,Q9H4A6,P55899,Q96RL7,Q9P253,P11279,Q92544,Q8TCT8,O95772,Q86Y82,Q15057,Q99805,Q14849,Q9NX40,Q92581,P35613,Q9BTU6,O75955,Q9BRK5,Q5T9L3,O00461,O15127,O15400,Q5VW38,Q9UH99,Q13510,Q9BWS9,Q9BUN8,Q9H0R1,P41440,P07602,Q9H223,P42892,Q9HC07,Q96SU4,Q9BXW6,P51790,O60826,O14773,P05067,Q8IV08,Q9Y287 57 +Copii coated er to golgi transport vesicle 0.527502649932282 2.321438919355409 0.0202631670783195 0.9999999931061502 0.15764057099913 35 Q5BJH7,Q9UEU0,Q9NR31,P49257,P01889,Q9Y282,P49755,O95070,Q9Y6B6,P10321,Q969X5,Q15363,P05067,Q12770,Q9Y3A6 15 +Exocytic vesicle 0.515118924538797 2.3090707285487846 0.0209396567550816 0.9999999963433436 0.1601883741763749 48 Q92542,O60499,O15126,Q96A57,O76024,P61026,Q12846,P11279,O43760,P50897,Q86Y82,Q9UEU0,Q9BVK6,O15400,O14908,P05067,O14656,Q7L0J3,P51790,Q92905,Q14141 21 +Respiratory chain complex iv 0.7776301771942715 2.2530675580306165 0.0242548896242753 0.99999999983752 0.1808243798224953 9 P14406,P15954,P13073,P00403 4 +Pore complex 0.7760140996580183 2.2455643235224594 0.0247319278108422 0.999999999896286 0.1808243798224953 9 Q9Y277,P21796,O96008,P45880,P12235 5 +Lumenal side of membrane 0.7604345605243955 2.2442078294083694 0.0248190325246562 0.9999999999044504 0.1808243798224953 10 P10619,P27824,Q8TCT8,P01889,P51572,P10321 6 +Integral component of cytoplasmic side of endoplasmic reticulum membrane 0.8516437201461017 2.2322960992837793 0.025595399522261 0.999999999954006 0.1838407996053641 2 Q8TCT8 1 +Tim22 mitochondrial import inner membrane insertion complex 0.8508007867378422 2.22854612101863 0.025844119365376 0.9999999999636148 0.1839139657163967 2 Q9Y5J6 1 +Gamma secretase complex 0.8429334082607434 2.1934825922591235 0.0282726274395817 0.9999999999963204 0.1936885969368358 2 Q92542 1 +Golgi apparatus subcompartment 0.4198551388794668 2.181382852774711 0.0291551108397898 0.999999999998402 0.1982547537105708 102 Q8NBN3,Q10713,Q9UL25,P0CG08,O60499,O15126,Q12893,Q96A57,P35670,Q9UNK0,Q8NBZ7,P61026,Q12846,Q9H4A6,P53367,P53365,Q9Y6B6,Q10472,Q9BTU6,Q5T9L3,O00461,O15127,P04062,P51572,Q8TBA6,Q15363,Q9BWS9,Q9BSR8,Q9NPR9,Q9HC07,P05067,Q8N6G5,O14828 33 +Tim23 mitochondrial import inner membrane translocase complex 0.8953094557964357 2.134550942760047 0.0327977082546484 0.9999999999999492 0.2197685852391772 6 O60830,O14925,Q99595 3 +Cell tip 0.8257937622927727 2.1167004640681606 0.0342852774376432 0.9999999999999876 0.2267353076574648 2 Q9BTU6 1 +Nuclear outer membrane 0.7027366553514635 2.11229759291255 0.0346609321948812 0.9999999999999912 0.2267353076574648 12 Q6NUM9,Q8IWB1,Q9UBM7,Q99720 4 +Nadh dehydrogenase complex 0.5569855343595351 2.111416600434478 0.034736519447198 0.999999999999992 0.2267353076574648 27 Q96CU9,P51970,O43676,Q9Y6M9,O96000,Q9P0J0,Q86Y39,P03886,Q9NX14,O75380,Q16795,O95168,Q9Y375,O43674 14 +Inhibitory synapse 0.824388873279008 2.1103832538573752 0.0348253577120942 0.9999999999999928 0.2267353076574648 2 P51790 1 +Mitochondrial large ribosomal subunit 0.5089268469372135 2.105548522042403 0.0352435882671886 0.999999999999995 0.227177269172234 34 Q13084,Q96GC5,Q9BRJ2,Q9BYD2,Q5T653,Q567V2,Q9NWU5,Q9HD33,Q7Z7H8,Q9BYD1 10 +Respiratory chain complex iii 0.7753258960031414 2.094917876870886 0.0361782934112833 0.999999999999998 0.227177269172234 8 P08574,P22695,Q9UDW1,P14927,O14949 5 +Mitochondrial intermembrane space protein transporter complex 0.8204551840404533 2.092676309506753 0.0363780594426126 0.9999999999999984 0.227177269172234 2 Q9Y5J6 1 +Presynaptic active zone 0.631843186426068 2.0796135260054855 0.0375609953472999 0.9999999999999994 0.2295459020165577 17 P41440,O75955,Q07021,P27824,Q7L0J3,Q9Y639,Q99623,Q12846,P05067 9 +Endosome membrane 0.3925157604729334 2.0780491490112407 0.0377048325406346 0.9999999999999996 0.2295459020165577 151 Q92542,Q14108,Q9UL25,Q8N4V1,P13473,O15126,Q93050,P01889,O15118,P10321,P55899,Q96RL7,Q9P253,P11279,Q8TCT8,O95772,Q86Y82,Q15057,Q99805,Q14849,Q92581,Q5T9L3,O00461,O15127,O15400,Q9UH99,Q9H0R1,Q9H223,P42892,Q9HC07,Q96SU4,P51790,Q8IV08,Q9Y287 34 +Acrosomal membrane 0.8170834504074092 2.0774770603068897 0.0377575503316995 0.9999999999999996 0.2295459020165577 2 P35613 1 +Platelet dense granule 0.9250790935203808 2.065772619720463 0.0388499545851015 1.0 0.2346332783494948 3 Q92520 1 +Organellar ribosome 0.486421726363912 2.0606784330919226 0.0393337284974653 1.0 0.2360023709847918 49 Q96GC5,Q9NWU5,Q96A35,Q9BYD1,Q9BRJ2,P82933,Q9BYD2,Q9Y2Q9,P49406,Q567V2,O95182,Q13084,Q9Y3B7,Q9P015,Q5T653,P82930,P82650,Q9Y2R9,Q9HD33,Q7Z7H8,Q9BYN8,P82912 22 +Cis golgi network 0.6501673735831947 2.0562488608219405 0.0397585348000351 1.0 0.2370021749768326 15 P24390,Q9NPR9,O00461,P30533,Q8TBA6,Q9Y3A6 6 +Blood microparticle 0.6129697859919014 2.0373802342768204 0.0416119530465985 1.0 0.24025014400489 18 P27105,P04062 2 +Intrinsic component of nuclear inner membrane 0.8126840244854875 2.021669181472463 0.0432105397362769 1.0 0.243357518269339 7 Q14739,Q9BTV4,Q9UH99,Q5SNT2 4 +Proton transporting two sector atpase complex 0.5830182211750614 2.012479463698928 0.0441694193542336 1.0 0.2472410180926007 21 Q8N511,P56385,P56134,P36542,Q93050,P36543,O75947,Q9Y487,O75964,P06576,Q96IX5,P24539 12 +Proton transporting atp synthase complex 0.7098616638612983 1.9997223829316748 0.0455302498474936 1.0 0.2487902938095189 10 P56385,P36542,O75947,O75964,P06576,Q96IX5,P24539 7 +Lumenal side of endoplasmic reticulum membrane 0.7532407841258213 1.9941309099158115 0.0461377500838942 1.0 0.2502886252443101 8 P27824,Q8TCT8,P01889,P51572,P10321 5 +Azurophil granule 0.4497182721995099 1.9674293145070467 0.0491337375482023 1.0 0.2562771083480101 71 Q92542,Q8NF37,Q9NZJ7,P10619,P11279,P07602,P27105,P13473,Q9H7Z7,O15260,O43681,O15400,Q99536,P10253,P16278,P17900,Q07065,P42785 18 +Intrinsic component of vacuolar membrane 0.8905291838634296 1.929015550129904 0.0537289317990485 1.0 0.269525461155883 3 O15118 1 +Transport vesicle 0.3956647569711615 1.9171916700985576 0.0552135859286044 1.0 0.2726704293393934 105 Q92542,Q9NR31,O60499,P01889,O15126,O15260,Q96A57,O76024,P10321,Q12846,P24390,P11279,P49257,P49755,Q9Y6B6,P50897,O43760,Q86Y82,Q12770,Q9UEU0,Q9BVK6,O00461,O15400,Q8TBA6,Q15363,O14656,Q7L0J3,Q9UKR5,P51790,Q92905,P05067 31 +Proton transporting two sector atpase complex proton transporting domain 0.7065668277668378 1.9169290198713007 0.0552469497354326 1.0 0.2726704293393934 9 P56385,Q93050,P24539,O75964 4 +Snare complex 0.5792877685270004 1.9023402734084829 0.0571266838103634 1.0 0.2760120828311245 19 Q9UEU0,Q9NZ43,Q12981,O60499,O15400,Q9P2W9,Q12846,Q5SQN1,Q86Y82 9 +Extrinsic component of endoplasmic reticulum membrane 0.7766226468108957 1.893573440439852 0.0582816516342283 1.0 0.2774076999040288 2 O14656 1 +Large ribosomal subunit 0.4234917721699821 1.8918862098460976 0.0585061435328091 1.0 0.2774076999040288 81 Q96GC5,Q02878,P39023,P27635,P61927,Q96A35,Q9NWU5,P84098,P18124,Q9BYD1,P46779,Q9BRJ2,P62424,Q9BYD2,P46776,Q567V2,P49406,P47914,P40429,P61513,Q13084,P46778,P62917,Q9Y3B7,Q5T653,P61313,P83881,P36578,Q9HD33,Q7Z7H8,Q9Y3U8,Q02543,P18077 33 +Endoplasmic reticulum plasma membrane contact site 0.7760606912053882 1.891000442459219 0.0586242851649037 1.0 0.2774076999040288 2 Q9NTJ5 1 +Oligosaccharyltransferase complex 0.7292744091779625 1.883530201548088 0.0596285508925453 1.0 0.2805537433690774 8 P61803,P46977,P04843,Q9H0U3,Q8TCJ2 5 +Mitochondrial crista 0.8779016295997668 1.8786391438592636 0.060293782498765 1.0 0.2805537433690774 3 Q9BUB7 1 +Micos complex 0.8538920987101815 1.8758962734433455 0.0606695244702311 1.0 0.2805537433690774 5 Q16891,Q5XKP0,Q6UXV4 3 +Platelet dense tubular network membrane 0.771565046361326 1.8703989764901816 0.0614284340056476 1.0 0.2805537433690774 2 P16615 1 +Platelet dense tubular network 0.771565046361326 1.8703989764901816 0.0614284340056476 1.0 0.2805537433690774 2 P16615 1 +Intrinsic component of synaptic vesicle membrane 0.6613457708824053 1.8260256884918085 0.0678463924775902 1.0 0.3053087661491562 11 P61020,O60499,O15126,Q7L0J3,O76024,P20020,Q86Y82 7 +Pigment granule 0.4478454475443604 1.8143206530306624 0.0696283737082368 1.0 0.3087867007930502 62 Q92542,P41440,P35613,P11279,O75955,P27824,P05023,P57088,Q93050,P04843,P49755,O43852,O14773,P27105,P55209 15 +Golgi associated vesicle membrane 0.5428271572713813 1.7939630596640874 0.072819065149025 1.0 0.3196173544325791 22 Q8N511,P24390,Q8TCT8,Q8IUH4,Q15363 5 +Dopaminergic synapse 0.8563263756586479 1.7921116626107343 0.0731150810793481 1.0 0.3196173544325791 3 O75955 1 +Caveola 0.59976933818872 1.7706008101792512 0.0766271071426578 1.0 0.3318098318724524 15 P09601,Q8WTV0 2 +Er ubiquitin ligase complex 0.8038376736003108 1.7618857711120526 0.0780885991489377 1.0 0.3340710284399801 6 Q6NTF9,Q9BUN8,Q9UBU6,Q9UBV2 4 +Emc complex 0.8008244701479031 1.7493889273602932 0.0802238135384825 1.0 0.3351674760245208 6 Q9P0I2,Q5J8M3,Q8N4V1,Q9NPA0 4 +Zymogen granule membrane 0.8431703204047234 1.7390848026831087 0.082019847413596 1.0 0.3391631528183835 3 Q15363,O15126 2 +Membrane microdomain 0.4303239876616402 1.730670886958266 0.0835104805844293 1.0 0.3407227607844717 69 P05023,P05141,P09601,Q9BTU6,P35613,O75955,Q12959,P41440,P13473,P21796,O15118,P50897,O14773,Q86Y82,P27105,Q8WTV0 16 +Signal peptidase complex 0.8350752540627562 1.7063639950999256 0.0879403298563277 1.0 0.3532586679227364 3 P67812 1 +External side of plasma membrane 0.5297772638978338 1.7053870588849036 0.0881222602988089 1.0 0.3532586679227364 22 P41440,P11279,O75955,O96005,P08183,P42892,P51790,P14735,P55899,P00813 10 +Integral component of synaptic vesicle membrane 0.7881856540084455 1.696831692481962 0.0897284851366584 1.0 0.3581336928497932 6 O60499,O15126,Q7L0J3,O76024,Q86Y82 5 +Mitochondrial permeability transition pore complex 0.8323403319323297 1.6780766545442003 0.0933321355544429 1.0 0.3658508505742049 4 P12235,P21796 2 +Gaba ergic synapse 0.6437526983324263 1.6701697386465872 0.0948857854143456 1.0 0.3681273222407135 10 P41440,O75955,Q07021,Q7L0J3,Q9Y639,Q99623 6 +Derlin 1 retrotranslocation complex 0.8284484449150047 1.6625145777973067 0.0964096428894469 1.0 0.370309841725993 4 Q9BUN8,Q9UBV2 2 +Endoplasmic reticulum lumen 0.4224794653763442 1.6477224552992316 0.0994096379097928 1.0 0.3786640979302483 69 P11047,Q9Y680,P30533,Q969H8,O76024,Q5JRA6,P27824,Q13217,Q9NWM8,O43681,Q9Y4L1,Q07065,Q14257,Q02818,Q9BTV4,P07237,P19022,Q8NBJ4,O00255,O14657,Q9NZ08,Q32P28,P13674,Q96AY3,O95881,Q8TED1,O14656,P50454,O43852,P05067,P14314 31 +Gpi anchor transamidase complex 0.7971320725766488 1.644972616844918 0.0999754582040908 1.0 0.3792457464105594 5 Q92643,O43292 2 +Golgi lumen 0.7966434142239579 1.6429670919378625 0.100389742149054 1.0 0.3792501370075375 5 O00461,P05067,Q9BRK5 3 +Hrd1p ubiquitin ligase erad l complex 0.7935438503397099 1.6302397635855237 0.1030508329287478 1.0 0.3797876010421243 5 Q6NTF9,Q9BUN8,Q9UBV2 3 +Coated vesicle 0.3794442082158084 1.6108983689131628 0.1072018755906598 1.0 0.3814392317528129 97 Q14108,Q9NR31,P01889,O15126,P10321,Q5BJH7,Q8N511,Q9P253,P24390,P49257,Q9Y282,P49755,Q9Y6B6,Q12770,Q9UEU0,Q5VW38,P51572,Q969X5,Q15363,P42892,O95070,P05067,Q9Y3A6 23 +Mitochondria associated endoplasmic reticulum membrane 0.630887465382541 1.6048190112423188 0.1085336408821513 1.0 0.3844046489307969 10 P27824,Q9Y320,O96008,Q96S66,Q96N66 5 +Synaptic vesicle membrane 0.5524785140487751 1.6032803336563328 0.1088727763856287 1.0 0.3844046489307969 17 P61020,Q92599,O60499,O15126,Q7L0J3,O76024,O43760,P20020,Q86Y82 9 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.7855152574533583 1.5972239135243234 0.1102158040167444 1.0 0.3873896734216303 5 P56385,P24539,O75964 3 +Myelin sheath 0.5781258968503385 1.5950820762541615 0.1106938830349035 1.0 0.3873896734216303 14 Q9NR77,Q12846,Q8IXJ6 3 +Cell pole 0.8071950534007891 1.5931839730742885 0.111118925536922 1.0 0.3873896734216303 3 Q9BTU6,P35241 2 +Postsynaptic specialization membrane 0.6036619080212438 1.5919044274959162 0.1114061805918413 1.0 0.3873896734216303 12 Q99720 1 +Postsynaptic density membrane 0.665902043603761 1.5853064942841637 0.1128967142357955 1.0 0.3899075459544944 8 Q99720 1 +Intrinsic component of peroxisomal membrane 0.7614465609887886 1.584940971578921 0.1129797464312587 1.0 0.3899075459544944 6 P56589,Q9Y3D6,O43808,Q8WVX9 4 +Endocytic vesicle membrane 0.433171174710088 1.5526943258840928 0.1204961785406586 1.0 0.4081752468646665 46 Q14108,Q5T9L3,P13473,Q93050,P10321,Q12846,Q8WTV0 7 +Neuron projection membrane 0.6189436995148503 1.5438293644436467 0.1226296755917122 1.0 0.4108541685882913 10 Q96SB3,Q12846,P20020 3 +Cell surface 0.3856410636808194 1.522212102903288 0.1279559435170794 1.0 0.4160094640008696 84 P36896,P30533,P01889,Q8TCT9,P10321,Q12846,P55899,Q8WTV0,P11279,O96005,Q08722,P08183,O15031,P07237,Q4KMQ2,O75955,P41440,P42892,P09429,Q13641,Q99623,P51790,O15258,P14735,P06576,P05067,P00813 27 +Brush border membrane 0.6524532808913168 1.5210514512518 0.1282469262660632 1.0 0.4160094640008696 8 P41440,Q14728 2 +Nuclear membrane 0.3611480439879773 1.49278889208362 0.1354924558469294 1.0 0.4318822030120877 121 Q5JTV8,Q03252,Q5XPI4,Q96S66,Q8IWB1,Q9UBM7,Q96KC8,Q99720,Q6NUM9,P50402,O76062,Q9BTV4,Q14728,Q9P035,P20700,Q5BJF2,Q5SNT2,O94901,Q9H1E5,Q8IXM6,Q9UH99,O15504,Q9BTX1,O75844,O14681,O14656,Q14739,P02545,Q86UE4 29 +Sarcolemma 0.4755540703186254 1.4763587717076871 0.1398476043818546 1.0 0.4410008090240065 26 Q92542,P05023,P35613,P11279,O75955,Q12959,Q96QD8 7 +Mhc protein complex 0.7754356379988785 1.4635123801268313 0.1433272285523781 1.0 0.4410008090240065 3 P01889,P10321 2 +Mhc class i protein complex 0.7754356379988785 1.4635123801268313 0.1433272285523781 1.0 0.4410008090240065 3 P01889,P10321 2 +Neuronal dense core vesicle 0.7746284661054823 1.460208976955497 0.1442326489129919 1.0 0.4410008090240065 3 Q96RL7 1 +Zymogen granule 0.7780240964795414 1.4596586933510909 0.1443838996621211 1.0 0.4410008090240065 4 Q15363,O15126 2 +Rough endoplasmic reticulum membrane 0.5198274328374182 1.458124400741132 0.1448062567763377 1.0 0.4410008090240065 18 Q9Y5M8,Q96A33,Q5BJF2,Q15041 4 +Proton transporting atp synthase complex coupling factor f o 0.7310504042949781 1.456740791671104 0.1451879451436166 1.0 0.4410008090240065 6 O75947,P56385,P24539,O75964 4 +Shelterin complex 0.6813711716774359 1.4517663439176771 0.1465665850487931 1.0 0.4425925166933951 2 Q9NYB0 1 +Plasma membrane raft 0.4974176020948709 1.4424769067829062 0.1491678817316422 1.0 0.4445724147243903 21 P09601,Q8WTV0 2 +Sperm annulus 0.7692523889825773 1.4381995587913798 0.1503774403846696 1.0 0.44531125894557 3 Q14141,Q16181 2 +Basal part of cell 0.4171789277511342 1.4321418224150049 0.1521032374439686 1.0 0.4462691567889751 53 Q14254,P35670,Q12846,P33527,Q12959,P08195,Q6P4Q7,P42785,P30825,P35613,O75955,Q9Y6M7,Q92796,P05023,P41440,P53985,P20020,P14735,Q9BY67 19 +Extrinsic component of mitochondrial inner membrane 0.7705573570180051 1.4294645670261914 0.1528707520494236 1.0 0.4462691567889751 4 P49748,Q8NI60 2 +Golgi associated vesicle 0.4282409903226356 1.42557114680381 0.1539921697543498 1.0 0.4473569994762441 34 Q8N511,P24390,Q8TCT8,Q8IUH4,Q15363 5 +Basolateral plasma membrane 0.4174574614502344 1.4045760554554605 0.1601473809663169 1.0 0.4551557143253219 46 P05023,P41440,P35613,P53985,O75955,Q12959,Q14254,P35670,P08195,Q9Y6M7,Q92796,Q12846,Q6P4Q7,P14735,P33527,Q9BY67,P30825 17 +Side of membrane 0.3880820089546597 1.402040002641025 0.1609033015602092 1.0 0.4555369907044715 77 P10619,Q9UL25,P01889,Q8TCT9,P10321,P55899,P11279,O96005,P27824,Q12959,Q8TCT8,Q96SB3,P08183,P07237,O75955,P51572,P41440,P42892,P51790,P17900,P14735,P00813 22 +Platelet alpha granule membrane 0.6701320595672918 1.3991426283877808 0.1617702167425465 1.0 0.4555369907044715 2 Q9UHQ9 1 +Smooth endoplasmic reticulum 0.5899998820729525 1.3948849203256513 0.1630505451651924 1.0 0.4563426843342886 10 P27824,P27635,O00264,Q9Y4L1,P05067 5 +Hulc complex 0.6681652149480166 1.3899304716453689 0.1645499914670576 1.0 0.4591394898685681 2 Q5VTR2 1 +Phagocytic vesicle membrane 0.4578488199298858 1.3748647197327035 0.1691733888048523 1.0 0.4661517606125844 27 P11279,P13473,P01889,Q93050,Q9Y487,P61026,Q03518,P10321,Q12846,Q9BZG1,Q03519 11 +Nuclear envelope 0.3380066289335504 1.3738654541988609 0.169483456154613 1.0 0.4661517606125844 197 Q5JTV8,Q03252,O15118,Q5XPI4,Q96S66,Q8IWB1,Q96KC8,Q9UBM7,Q99720,Q6NUM9,P50402,P41208,O76062,Q9BTV4,Q14728,Q9P035,Q9NUQ2,Q5BJF2,Q5SNT2,P20700,O94901,Q9H1E5,P80303,Q8IXM6,Q9UH99,O15504,P42167,Q9BTX1,P57088,O14880,Q12981,O75844,Q99735,O14681,Q9NQC3,O14656,P05067,O15173,Q14739,P02545,Q86UE4,Q86Y07 42 +Golgi medial cisterna 0.7509836987071419 1.3633336612437483 0.1727773779514412 1.0 0.4699364841674355 3 P04439,Q16706 2 +Dense core granule membrane 0.6569261028378723 1.3372856320979107 0.1811294191188148 1.0 0.4843255972405625 2 Q709C8 1 +Ciliary rootlet 0.7419834274012831 1.326426076953886 0.184698605951983 1.0 0.4886262831813269 3 P05067 1 +Tertiary granule 0.4082380604835803 1.306007249798 0.1915500921582944 1.0 0.4992816679316346 43 Q4KMQ2,P11279,P09960,Q5T9A4,P13473,Q93050,O15400,Q08722,Q13510,P27105,P42785 11 +Presynaptic active zone membrane 0.6951266126732221 1.3042055906607513 0.1921634942248364 1.0 0.4992816679316346 6 Q9Y639,Q12846,P27824,P20020 4 +Glial cell projection 0.7148135981897233 1.3041036783361593 0.1921982349235458 1.0 0.4992816679316346 5 Q8IXJ6 1 +Transcription export complex 2 0.7363687464867938 1.30340053641718 0.1924380534819265 1.0 0.4992816679316346 3 P41208,Q5JVF3 2 +Copi coated vesicle membrane 0.5608219593448625 1.2988042313193124 0.1940111221726437 1.0 0.5001787139469076 11 Q8N511,P24390 2 +Recycling endosome 0.4040628927364051 1.2936925309705192 0.1957716462805496 1.0 0.5001787139469076 51 Q9UEU0,Q9H223,P01889,O15126,Q9UNK0,Q96A57,O15400,O15127,P10321,P51790,O14773,Q86Y82,P05067,O14828,Q92581 15 +Vacuolar proton transporting v type atpase v0 domain 0.7333616893627463 1.291069557510661 0.1966795590629049 1.0 0.5001787139469076 3 Q93050 1 +Proton transporting v type atpase v0 domain 0.7333616893627463 1.291069557510661 0.1966795590629049 1.0 0.5001787139469076 3 Q93050 1 +Intrinsic component of presynaptic membrane 0.6920316464294632 1.291029719543923 0.1966933722601673 1.0 0.5001787139469076 6 Q92542,Q9Y639,P27824,P20020 4 +Cytoplasmic ubiquitin ligase complex 0.5669642924179026 1.2753920644072392 0.2021705060640175 1.0 0.5098695729856266 10 Q6NTF9,Q9BUN8,Q9UBU6,Q9UBV2 4 +Apical plasma membrane 0.4032199571937578 1.264875300049044 0.2059160328748239 1.0 0.514427518345822 45 Q99797,Q16181,Q14254,P33527,P36551,Q12959,P36543,P08195,P08183,P30825,O75955,Q9Y6M7,P05023,P41440,P53985,P35241,P51790,P20020,Q86UE4 19 +Dendrite cytoplasm 0.5408917810549387 1.2496291876619756 0.2114350357974586 1.0 0.5211683143206642 12 Q8N2K0,P27824,Q14254,P23246,Q9UQB8 5 +Caspase complex 0.634169362267171 1.2286092911265063 0.2192183302680908 1.0 0.5289429601177318 7 Q92643,O43292 2 +Microtubule organizing center attachment site 0.7184208604884816 1.2181630934462562 0.2231620014901281 1.0 0.5289429601177318 4 Q9UH99 1 +Endosome lumen 0.7183019398369311 1.217681082667855 0.2233451885876478 1.0 0.5289429601177318 4 P05067,Q9UIQ6,P30533 3 +Copi coated vesicle 0.5340037736381568 1.211677252266193 0.2256359500699316 1.0 0.5297539697294047 12 Q8N511,P24390 2 +Trans golgi network membrane 0.4170765282027739 1.1933791915264962 0.2327209006066497 1.0 0.5386809306584643 31 Q9HC07,O60499,O15126,O15127,P53367,P35670,P53365,P05067 8 +Phagocytic vesicle 0.3952899361123676 1.1862608048831207 0.2355193201684611 1.0 0.5386809306584643 44 P13473,P01889,Q93050,Q9UNK0,Q9Y487,P61026,Q03518,P10321,Q12846,P04439,P08670,P11279,P51809,Q9BZG1,Q86Y82,O14964,O75396,O00159,P42345,P51790,Q03519 21 +Mitochondrial alpha ketoglutarate dehydrogenase complex 0.7079063614785233 1.1755641684357567 0.2397690810538708 1.0 0.5434765837221073 4 O14874 1 +Early endosome 0.3379714151787619 1.1619723214969853 0.2452467080795035 1.0 0.5513964802350123 118 Q92542,Q9GZP9,Q9UL25,Q8N4V1,P01889,Q96A57,P10321,Q9P253,Q92544,Q86Y82,Q92581,O75955,Q5T9L3,O15400,Q5VW38,Q13510,Q9BUN8,P41440,Q9H223,Q9HC07,P51790,P05067,Q8IV08 23 +Trans golgi network 0.3708693347435343 1.1540915626420734 0.2484626321498326 1.0 0.5529070710777985 74 Q9UL25,O60499,O15126,Q9UNK0,Q96A57,P35670,P61026,Q12846,Q9H4A6,P53367,P53365,Q9BTU6,Q5T9L3,O15127,P04062,Q9BWS9,Q9BSR8,Q9NPR9,Q9HC07,P05067,O14828 21 +Presynapse 0.3374240048681389 1.1491548524167237 0.2504921335265473 1.0 0.5529070710777985 106 Q92542,O60499,O15126,Q96A57,O76024,P61026,Q12846,Q9P253,P11279,P27824,P50897,O43760,Q9UQB8,Q86Y82,Q9BTU6,Q9UEU0,Q9BVK6,O75955,O15400,P41440,P05067,O14656,Q13641,Q7L0J3,Q9Y639,Q99623,Q5SQN1,P51790,Q92905,Q14141,P07196 31 +Integral component of presynaptic active zone membrane 0.6775868539853199 1.1490027703722006 0.2505548383097649 1.0 0.5529070710777985 5 Q9Y639,P27824,P20020 3 +Intrinsic component of presynaptic active zone membrane 0.6775868539853199 1.1490027703722006 0.2505548383097649 1.0 0.5529070710777985 5 Q9Y639,P27824,P20020 3 +Hops complex 0.6535332940684582 1.1270150386582622 0.259736122692864 1.0 0.561116592646823 6 Q9P253 1 +Microbody 0.3832493057904428 1.1267880490211537 0.2598321045771317 1.0 0.561116592646823 59 Q9Y3D6,P28288,Q5T8D3,P56589,Q9UKU0,P04035,O15254,P08670,Q8WVX9,O14678,Q8TB36,Q96K12,O00116,P40855,Q8N4Q0,O75381,Q96CN7,Q6IAN0,P51648,Q9NR77,O43808,Q13011,P14735 23 +Sodium potassium exchanging atpase complex 0.6919617762788125 1.1216430197276837 0.2620142525871234 1.0 0.561116592646823 3 P05023,P05026 2 +Cation transporting atpase complex 0.6919617762788125 1.1216430197276837 0.2620142525871234 1.0 0.561116592646823 3 P05023,P05026 2 +Dendritic spine membrane 0.6872677564272132 1.1025099740133886 0.2702400247522742 1.0 0.5702996384427306 3 Q96SB3 1 +Dendrite membrane 0.6864249927696288 1.0887243751587197 0.2762754494430537 1.0 0.575103996799826 4 Q96SB3 1 +Dense core granule 0.6820036328812541 1.0708977423014348 0.2842154111375008 1.0 0.5797994387205017 4 O00255,Q96RL7 2 +Early endosome membrane 0.3790836356518501 1.0658185855734748 0.2865056576645086 1.0 0.5808999636596588 56 Q9UL25,Q5T9L3,Q9H223,Q92581,Q8N4V1,P01889,O15400,Q9HC07,P10321,P51790,Q86Y82,Q8IV08,Q86YV9 13 +Cell trailing edge 0.635660596861211 1.0510005581634032 0.2932583334846994 1.0 0.5865166669693989 6 P41440,O75955 2 +Transport vesicle membrane 0.3798339830151069 1.048939895377642 0.2942057822648665 1.0 0.5871324089546683 49 Q9NR31,P49257,O60499,P01889,O15126,P49755,O76024,Q7L0J3,Q9Y6B6,P10321,O43760,Q86Y82,Q12770,Q15363 14 +Endocytic vesicle 0.3395779714277588 1.0444728896417137 0.2962666557548865 1.0 0.5886856926038655 91 P08670,Q14108,P11279,Q5T9L3,Q9H223,O00461,P13473,Q93050,O15400,P01889,Q969Q5,P10321,Q12846,P51790,Q86Y82,Q8WTV0,Q03519 17 +Endoplasmic reticulum quality control compartment 0.6494986675586283 1.0323445320512088 0.3019107465167088 1.0 0.5973147959102126 5 Q9BUN8 1 +Dihydrolipoyl dehydrogenase complex 0.6302639419992673 1.028094737802636 0.3039052657093375 1.0 0.5973983595742438 6 O14874 1 +Synaptic membrane 0.3773924764059425 1.023231667351926 0.3061983235178549 1.0 0.5993391492311104 48 Q92542,Q9BTU6,Q8NCG7,P27824,Q12959,Q12846,Q9UQB8,Q96SB3,Q99720 9 +Cell body membrane 0.6655424395727983 1.0143167977085292 0.3104316112527956 1.0 0.603763176123022 3 P55011,P20020 2 +Specific granule 0.3742706452646155 0.9841580210629326 0.3250378225378474 1.0 0.6104805792274325 40 Q4KMQ2,P27105,O00264,Q08722,P30519,Q12846,P51790,Q07065,O15121 9 +Translocon complex 0.6599336479431952 0.9822682730036776 0.3259677005365384 1.0 0.6104805792274325 4 Q15041 1 +Sec61 translocon complex 0.6599336479431952 0.9822682730036776 0.3259677005365384 1.0 0.6104805792274325 4 Q15041 1 +Ribosomal subunit 0.3251245954396519 0.9811461836988372 0.3265206583885287 1.0 0.6104805792274325 127 Q96GC5,Q02878,P39023,P27635,P61927,Q96A35,Q9NWU5,P84098,P18124,Q9BYD1,P62266,P46779,Q9BRJ2,P62424,P82933,Q9BYD2,P46776,Q567V2,P49406,P47914,P40429,P61513,Q13084,P46778,P62917,Q9Y3B7,Q5T653,P82650,P82930,Q07020,P61313,P83881,Q9Y2R9,P36578,Q9HD33,Q7Z7H8,Q9BYN8,Q9Y3U8,P82912,Q02543,P18077,P62847,P62854 43 +Mitochondrial small ribosomal subunit 0.4572453380792813 0.8910778090667697 0.3728874289174992 1.0 0.6599314949925005 14 Q9BYN8,P82912,P82933,P82650,P82930,Q9Y2R9 6 +Proton transporting v type atpase complex 0.4843433799452363 0.8889877448697541 0.3740096661470251 1.0 0.6602709106210944 11 Q8N511 1 +Recycling endosome membrane 0.3917349182245878 0.8862534798307056 0.3754809510181416 1.0 0.660482355431778 28 P04439,Q9UEU0,Q9H223,P01889,O15126,O15127,P10321,P61026,Q86Y82,O14828,Q92581 11 +Gtpase complex 0.5174954641375222 0.8681239120549721 0.3853265019400926 1.0 0.66741458260567 8 Q9UBI6,P09471,P63218 3 +Intrinsic component of synaptic membrane 0.4702024554707118 0.8597301316153273 0.3899378210682056 1.0 0.6703425463307354 12 Q92542,P27824,Q9Y639,Q15375,P51790,P20020 6 +Cytosolic large ribosomal subunit 0.3598568738496757 0.8497930426271103 0.3954401584091289 1.0 0.6744456218411423 47 Q02878,P39023,P27635,P61927,P84098,P18124,P62910,P46779,P62424,P46776,P47914,P40429,P61513,P46778,P62917,Q07020,P61313,P83881,P36578,Q9Y3U8,Q02543,P18077 22 +Septin cytoskeleton 0.5829112291780851 0.8289297536175394 0.4071441578726267 1.0 0.689121992710654 6 Q14141,Q16181,Q9NVA2,Q15019 4 +Dna replication preinitiation complex 0.4717169294282297 0.8217996007590022 0.4111909610070987 1.0 0.689121992710654 11 Q9BRT9,Q9Y248 2 +Postsynaptic specialization intracellular component 0.6193725430964959 0.8217619385788344 0.4112123998259329 1.0 0.689121992710654 4 P50570,Q9UQB8 2 +Postsynaptic density intracellular component 0.6193725430964959 0.8217619385788344 0.4112123998259329 1.0 0.689121992710654 4 P50570,Q9UQB8 2 +Chromocenter 0.5440509311079543 0.821436620260051 0.4113976116385764 1.0 0.689121992710654 7 Q96GD4,O43482 2 +Protein complex involved in cell adhesion 0.5436920483281747 0.8157916337858676 0.4146193190351832 1.0 0.6907813700078007 2 P23229 1 +Integrin complex 0.5436920483281747 0.8157916337858676 0.4146193190351832 1.0 0.6907813700078007 2 P23229 1 +Ficolin 1 rich granule membrane 0.4129437084312647 0.8086948003383294 0.4186907197764939 1.0 0.6963008709326476 19 P11279,Q5T9A4,P13473,Q93050,P42785 5 +High density lipoprotein particle 0.5403203146951294 0.8008640981734279 0.4232103263481854 1.0 0.7023703906658705 2 Q9BUR5 1 +Presynaptic membrane 0.4108830089720272 0.7949232715192439 0.4266581363172697 1.0 0.7031816322069184 19 Q92542,Q9BTU6,P27824,Q96A49,Q9Y639,Q12846,P20020 7 +Nuclear pore nuclear basket 0.4812015223706868 0.789950927844191 0.4295564273927039 1.0 0.7041657149044682 9 P41208,Q5JVF3,P12270 3 +Gap junction 0.5886685813502581 0.7838039726328625 0.4331551424692947 1.0 0.7052569237730044 5 Q99797 1 +Proximal dendrite 0.5318909806125198 0.7638123644515745 0.4449790674511824 1.0 0.7197761027832573 2 P49840 1 +Tertiary granule lumen 0.4297547268543068 0.7606375740828321 0.4468735706199074 1.0 0.7197761027832573 15 P09960 1 +Mcm complex 0.5627453744985192 0.7457145255163394 0.4558398827026106 1.0 0.7252357232599594 6 P33993,P33991 2 +Organelle envelope lumen 0.3481975979877755 0.7153861664736126 0.4743704580445738 1.0 0.7355947305488492 34 Q9Y5J9,Q16891,O14925,Q9Y5J6,Q9H078,Q53H12,O60313,P05067,Q9H4A6,P51970 10 +Neurotransmitter receptor complex 0.58469381900567 0.6961221564096364 0.4863523320687988 1.0 0.7462185691510658 3 Q8N2K0 1 +Ampa glutamate receptor complex 0.58469381900567 0.6961221564096364 0.4863523320687988 1.0 0.7462185691510658 3 Q8N2K0 1 +Mitochondrial tricarboxylic acid cycle enzyme complex 0.4767014674270675 0.6749069041778765 0.4997349137773414 1.0 0.7559890117626167 8 P12694,O14874 2 +Mhc class i peptide loading complex 0.561130955014806 0.6748500733244115 0.4997710233331103 1.0 0.7559890117626167 5 Q03519,Q03518 2 +Tertiary granule membrane 0.4347237868636129 0.6671584894683245 0.5046709029888756 1.0 0.7607354498255958 12 Q08722,Q4KMQ2,P27105 3 +Plasma membrane signaling receptor complex 0.4410332589634631 0.6607271614385126 0.5087873017719955 1.0 0.7621105367409438 11 Q8N2K0,P36896 2 +Ion channel complex 0.389956804693264 0.655920651664976 0.5118751797635852 1.0 0.7621105367409438 19 Q4KMQ2,Q8N2K0,Q9C0H2,Q96ER9,Q92796,Q96S66 6 +Er to golgi transport vesicle membrane 0.3739226431761326 0.6337268031366868 0.5262591296662531 1.0 0.7669521616679916 23 Q9NR31,P49257,P01889,P49755,Q9Y6B6,P10321,Q15363,Q12770 8 +Endoplasmic reticulum tubular network 0.4355199988940871 0.6322555186398428 0.5272199244042106 1.0 0.7669521616679916 11 P50402,Q00765,Q9NQC3,P61026,Q8NHH9 5 +Autophagosome 0.3353160048598657 0.6009034514353409 0.5479042942526426 1.0 0.7766118828404646 34 Q9P253,Q9UMX0,P13473,Q96A57,Q969Q5 5 +Flotillin complex 0.4929137307820702 0.59902311096173 0.5491574731577096 1.0 0.7766118828404646 7 P41440,O75955 2 +Axolemma 0.5584598088814005 0.5987440207284286 0.5493435971410854 1.0 0.7766118828404646 3 O94832,Q01082 2 +Myofilament 0.5397993151579007 0.592863483667759 0.5532725178405924 1.0 0.7766118828404646 5 P09493 1 +Striated muscle thin filament 0.5397993151579007 0.592863483667759 0.5532725178405924 1.0 0.7766118828404646 5 P09493 1 +Postsynaptic membrane 0.3402884280800946 0.5773584742234098 0.5636973200275737 1.0 0.7842911653805853 32 P27824,Q8NCG7,Q99720,Q12959 4 +Pre snornp complex 0.4756954200617994 0.5296774676447585 0.5963355730135693 1.0 0.8071213139380834 2 Q9Y2X3 1 +Lamin filament 0.5360627998641705 0.5190982229181068 0.6036922475194713 1.0 0.8114048070613099 3 P02545 1 +Main axon 0.3993011385668946 0.5175001664852051 0.6048070527442388 1.0 0.8117147286830574 13 Q12959,Q8IXJ6 2 +Secretory vesicle 0.2960019299588713 0.5007597941485724 0.6165401847615788 1.0 0.8199537254269679 284 Q92542,Q9NZJ7,Q9GZT3,P10619,P09960,O60499,P13473,O15126,Q14254,Q96A57,Q93050,P45880,Q9H0U3,P30519,Q13162,Q969Q5,O76024,P10321,P16278,Q12846,Q96RL7,P11279,P22466,Q5T9A4,O43681,P49755,Q08722,P50897,O43760,Q9UQB8,Q86Y82,Q07065,O15121,P42785,P08236,Q8NF37,P01889,P35613,Q9UEU0,Q9BVK6,Q4KMQ2,O15260,O00255,Q9H7Z7,O15400,O00264,P10253,Q13510,Q15363,Q8N2G8,P61916,P27105,P07602,Q92520,P42892,P12956,P09429,Q99536,P05067,O14656,Q7L0J3,Q6UXV4,P17900,Q92905,P51790,Q14141,P12814 67 +Atpase dependent transmembrane transport complex 0.5119451880761743 0.4899900450028268 0.6241409432542584 1.0 0.8220392911153647 5 P05023 1 +Prespliceosome 0.4180743243243083 0.4850976362863763 0.6276070886899403 1.0 0.8254202111996636 9 P09234,P26368,Q15459,Q15428,P08621,O75400,Q9Y383,O75533 8 +External encapsulating structure 0.317840892664871 0.4705074508203519 0.6379925122428176 1.0 0.8336032511252349 37 Q9NZJ7,P07602,Q53GQ0 3 +Intrinsic component of postsynaptic membrane 0.4273316766421422 0.453131290882548 0.6504542046660351 1.0 0.8416972604696203 8 P51790,Q9Y639,Q15375,P27824 4 +Cytoplasmic side of endoplasmic reticulum membrane 0.4065471213397598 0.4326319514904141 0.665282173273023 1.0 0.8458850901172231 9 Q8TCT8,Q8TCT9 2 +Uniplex complex 0.5067453625632453 0.4209152874278576 0.6738169416287934 1.0 0.8531916585037687 3 Q8NE86,Q8IYU8 2 +Pcg protein complex 0.4417557681485762 0.3927016461511537 0.6945398546922263 1.0 0.8746057429457665 7 Q16576,Q15022,Q92769,Q9UQR0,Q14781,Q14157 6 +Esc e z complex 0.4929735806633014 0.3775938574800567 0.7057323284824351 1.0 0.8820602530170999 3 Q15022,Q16576 2 +Neuronal ribonucleoprotein granule 0.4901630129286191 0.3689962538870503 0.7121305170229073 1.0 0.8870228149620474 3 Q99729,O60828 2 +Chloride channel complex 0.463521594456218 0.3671284066129469 0.713523239098139 1.0 0.8875532974147582 6 Q9C0H2,Q96S66 2 +Ribosome 0.2829350443788465 0.3597629361292241 0.7190244225183022 1.0 0.8883774157090194 144 Q96GC5,Q02878,P39023,P27635,P61927,Q96A35,Q9NWU5,P84098,P18124,Q9BYD1,P62266,P46779,P27824,Q9BRJ2,P62424,P82933,Q9BYD2,P46776,Q567V2,P49406,P47914,P40429,P20290,P61513,Q13084,P46778,P62917,Q9Y3B7,Q5T653,P82650,P82930,Q07020,P61313,P83881,Q9Y2R9,P36578,Q9HD33,Q7Z7H8,Q9BYN8,Q9Y3U8,P82912,Q02543,P18077,P62847,P62854 45 +Ap type membrane coat adaptor complex 0.3621941698177784 0.3579540283241221 0.7203777171184966 1.0 0.8888531509607257 14 Q9P253,Q96CW1,P61966,Q92572,Q9H0R1 5 +Oxoglutarate dehydrogenase complex 0.4848229342327227 0.3528986450827043 0.7241644266349327 1.0 0.8912960532767068 3 Q02218,P09622 2 +Intrinsic component of mitochondrial outer membrane 0.3611792840551388 0.35271860876473 0.7242994071290014 1.0 0.8912960532767068 14 Q9Y3D6,Q15388,O95140,O96008,Q8TB36 5 +Polysomal ribosome 0.3260904023915523 0.3427370305733077 0.7317963018149976 1.0 0.8969145595008915 26 P62273,P62266,P62910,Q9Y3U8,Q02878,P62424,P62917,Q02543,Q07020,P84098,P62854,P83881,P20290 13 +Cation channel complex 0.3759663837257528 0.3407126168099074 0.7333199395587542 1.0 0.8975836060199152 11 Q8N2K0,Q96ER9 2 +Cytolytic granule 0.4645423251561047 0.3296280892167282 0.7416809956486212 1.0 0.903001530511186 5 P11279 1 +Secretory granule 0.2852063328448259 0.304329419506988 0.760876933909884 1.0 0.92270148656443 252 Q92542,Q9NZJ7,P10619,P09960,P13473,Q93050,P01889,O15260,Q969Q5,P45880,O76024,P30519,P10321,Q12846,P16278,Q96RL7,P11279,P22466,Q5T9A4,O43681,Q08722,Q9UQB8,Q07065,O15121,P42785,Q8NF37,Q4KMQ2,P35613,Q9H7Z7,O15400,O00264,P10253,Q13510,Q15363,P61916,P07602,Q92520,P42892,P12956,Q99536,P05067,O14656,Q6UXV4,P17900,P51790,P27105 46 +Coated vesicle membrane 0.3036657872631358 0.2958315246930652 0.7673587467361824 1.0 0.9282710952040188 59 Q8N511,Q14108,P24390,Q9NR31,P49257,P01889,P49755,Q9Y6B6,P10321,Q15363,Q12770 11 +Receptor complex 0.3210178095758085 0.2956569006490628 0.7674921146621463 1.0 0.9282710952040188 25 Q8N2K0,P36896,P05067,O76062,O15031 5 +Neurofilament 0.4618345251241347 0.2778533151490489 0.7811249623259378 1.0 0.9398069664681664 4 P07197,P07196 2 +Laminin complex 0.4015172801348732 0.2746838246212529 0.7835591593978659 1.0 0.9402709912774392 2 P11047 1 +Phospholipid translocating atpase complex 0.3967406574880535 0.2611530007450354 0.7939745206663398 1.0 0.9438327103542652 2 Q9NV96 1 +Endoplasmic reticulum tubular network membrane 0.4508793048687631 0.2584482776410678 0.7960609616161793 1.0 0.9438327103542652 3 Q9NQC3 1 +Paraspeckles 0.4200454174748528 0.2289930862961095 0.8188742897060459 1.0 0.9582558041569372 6 Q8WXF1,P23246 2 +Endoplasmic reticulum chaperone complex 0.3897025763380951 0.2112700520935387 0.8326765504518896 1.0 0.9651478198419629 7 P07237 1 +Intrinsic component of postsynaptic specialization membrane 0.4223322402176227 0.2077177293210161 0.8354493736081454 1.0 0.96629068764334 5 P19022,Q9Y639,Q15375 3 +Wash complex 0.4209481885838787 0.2041165893062516 0.838262390847015 1.0 0.9679558173554212 5 Q2M389,Q12768 2 +Collagen containing extracellular matrix 0.2931627054544126 0.1932140846178595 0.8467913086407846 1.0 0.9716930266653002 32 Q9NZJ7,P07602,Q12959,P49257,P50454 5 +Photoreceptor inner segment 0.3785830152853657 0.1775227672416221 0.8590977835616327 1.0 0.9748476703455856 7 P35613 1 +Tricarboxylic acid cycle enzyme complex 0.3328151572333012 0.1735277613855357 0.8622366084443622 1.0 0.9755682424618384 12 P12694,O14874 2 +Spindle pole centrosome 0.3989674166936399 0.1709459497761905 0.8642662656961899 1.0 0.9755682424618384 6 P50402 1 +Plasma membrane protein complex 0.2866702255489447 0.1699539527888401 0.8650463500696475 1.0 0.9755682424618384 72 Q92542,P05023,Q8N2K0,P41440,P36896,O75955,Q12959,P01889,O14678,Q14254,P09429,P49755,P08195,Q9UBI6,Q92796,P10321,Q9UBC2 17 +Nbaf complex 0.3512524627075748 0.1635929749228424 0.870051575397254 1.0 0.976414848673202 8 O14497,Q969G3,P51532,Q8TAQ2,Q92785,Q12824,Q96GM5 7 +Ubiquitin conjugating enzyme complex 0.4055649241146775 0.156246337815139 0.8758388529328638 1.0 0.980512276819962 3 O75150,Q5VTR2 2 +Box c d rnp complex 0.388185654008447 0.143802580521516 0.8856563650961506 1.0 0.9883407699115776 6 P22087,O00567,Q14978,Q9Y2X3,P55769 5 +Dendritic growth cone 0.397695334457568 0.141509073225749 0.8874677927733314 1.0 0.9883407699115776 3 P07900,P08238 2 +Dendrite terminus 0.397695334457568 0.141509073225749 0.8874677927733314 1.0 0.9883407699115776 3 P07900,P08238 2 +Immunological synapse 0.3185172400797466 0.1315513009162328 0.8953392068818675 1.0 0.9934851020972468 13 Q9Y639,Q9UJZ1,O15400,Q12959 4 +Plasma membrane region 0.268462221112065 0.126840175550407 0.8990668970325637 1.0 0.9955891573894976 201 Q92542,Q15758,Q99797,Q9UL25,P61966,Q16181,Q14254,P35670,Q12846,P33527,Q8WTV0,Q99720,P36551,P21281,O75935,Q8NCG7,P27824,Q12959,Q9H0H5,P09493,P36543,Q9H4M9,P08195,Q8NBU5,Q9BZG1,Q6P4Q7,Q9UBC2,Q9UQB8,P08183,Q96SB3,P40855,Q14728,P30825,P09601,P35613,Q9BTU6,O75955,O00255,P46934,Q9Y6M7,Q92796,P53985,P05023,P41440,P14735,Q86UE4,P35241,P05067,Q9Y639,P51790,Q9BY67,O75251,P20020,Q14141 54 +Extrinsic component of organelle membrane 0.3085337412526587 0.1177133930053907 0.9062947544802442 1.0 0.9976758439647754 16 Q8NI60,P49748,O14656 3 +U2af complex 0.3830803822372214 0.1165570427922466 0.9072110805005064 1.0 0.9976758439647754 3 P26368,Q15637 2 +Nuclear lamina 0.3813479929434274 0.1129600924860421 0.910062194229988 1.0 0.9976758439647754 5 P02545 1 +B wich complex 0.3531232414181312 0.1080970894654779 0.913918676896898 1.0 0.9976758439647754 7 Q9NY93,Q9NR30,Q9UIG0,O60264,P35659,O75533 6 +Nuclear inclusion body 0.3298620883760238 0.0995160260010328 0.9207285641525496 1.0 1.0 8 P49790,Q9UNE7,Q86U42,P52948,Q9UBU9,P49792,P12270 7 +Nucleotide activated protein kinase complex 0.3750351419735636 0.0893468349952872 0.9288062739316368 1.0 1.0 4 P54646,P10644,P54619 3 +Intrinsic component of postsynaptic density membrane 0.3735608066172621 0.0870727762064444 0.9306136646195364 1.0 1.0 4 Q9Y639,Q15375 2 +Apical part of cell 0.2818639195242763 0.0811499359783461 0.9353227134368592 1.0 1.0 61 Q99797,Q16181,Q14254,P33527,P36551,Q12959,P36543,P08195,P41208,P08183,P30825,O75955,Q9Y6M7,P05023,P41440,P53985,P35241,P05067,P51790,P20020,Q86UE4 21 +Proton transporting atp synthase complex catalytic core f 1 0.3570795754302051 0.0637646514795458 0.9491576249880084 1.0 1.0 4 P06576 1 +Pericentriolar material 0.3433633295838079 0.0481135449535843 0.9616257513960752 1.0 1.0 5 Q96SN8,Q15154,Q86VS8,P23258 4 +Cop9 signalosome 0.2984639331608489 0.0421339867326882 0.9663918867234376 1.0 1.0 11 Q9BT78,Q9UNS2,Q92905,Q99627 4 +Anchored component of plasma membrane 0.3139404159640304 0.0388326849066325 0.9690237856926712 1.0 1.0 3 Q9NQX3,P36551 2 +Neuron projection terminus 0.2845629606841242 0.0344761452439136 0.972497464375132 1.0 1.0 19 Q13641,P51790,P43378,Q9UQB8 4 +Cohesin complex 0.3301462317210449 0.0307151070446722 0.9754967431676592 1.0 1.0 5 Q14683,Q8WVM7,Q8N3U4,Q9UQE7 4 +Dendritic shaft 0.3169074508186571 0.0296934096870014 0.976311567913773 1.0 1.0 7 P05067,Q9UQB8 2 +Autophagosome membrane 0.2899809824930027 0.0270964327592096 0.9783828199632748 1.0 1.0 13 P13473 1 +Cluster of actin based cell projections 0.2623960159885764 0.0205231884179623 0.9836260142881712 1.0 1.0 35 P41440,Q9Y6M7,P12814,Q96QD8,Q14728 5 +Cyclin cdk positive transcription elongation factor complex 0.2762788083192892 0.0195420113824092 0.9844087231965832 1.0 1.0 3 Q9NYV4,O75909 2 +Lateral plasma membrane 0.278071106636164 0.0139105132788679 0.9889013741581876 1.0 1.0 23 Q8TAA9,Q12959 2 +Tubular endosome 0.3041889232499295 0.0132072071102932 0.9894624797001008 1.0 1.0 4 Q9Y5X3,Q96QK1,Q9UNH7 3 +Insulin responsive compartment 0.3153305203938124 0.0093832046158893 0.9925133957653792 1.0 1.0 6 Q9Y4I1,Q6IQ22,P61026,P20338,Q5VZ89 5 +Clathrin coat of endocytic vesicle 0.3039932508436466 0.0035905007893913 0.9971352010099483 1.0 1.0 5 P63010,Q96CW1,O95782,P53680 4 +Intermediate filament 0.2771210258619551 0.0011929852365239 0.9990481357242962 1.0 1.0 21 P08670,P20700,Q03252,P07197,P48729,P02545,P07196 7 +Endoplasmic reticulum exit site 0.2787067701120801 0.0005204887173064 0.99958471010714 1.0 1.0 18 P04439,Q9NR31,Q9Y6B6,Q5JRA6,Q969M3,Q9Y3A6,Q96PC5 7 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..574e9f1d0753e717cdb4db447fcd1beaea6ac0d2 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Activin receptor complex", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical cortex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atg1 ulk1 kinase complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Cbm complex", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Checkpoint clamp complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine head", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Deuterosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mks complex", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Procentriole replication complex", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Smad protein complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Super elongation complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADNP", "ADPGK", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP5M1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID4A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG3", "ATG5", "ATG7", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRI3BP", "BRIP1", "BRIX1", "BRMS1L", "BRPF3", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "C12orf43", "C12orf57", "C12orf73", "C16orf62", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C8orf59", "CAB39", "CACTIN", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CASP2", "CASP8", "CAST", "CBFB", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC8", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPI", "CENPK", "CENPQ", "CENPV", "CEP170", "CEP250", "CEP290", "CEP350", "CEP44", "CEP55", "CEP97", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGN", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHML", "CHMP1A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLN5", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG4", "COG5", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD9", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTC", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND4C", "DERL1", "DERL2", "DFFA", "DFFB", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM208A", "FAM234B", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXL18", "FBXO21", "FBXO22", "FBXO7", "FCGRT", "FDFT1", "FDXR", "FECH", "FEM1B", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FOCAD", "FOXK1", "FOXRED1", "FPGS", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GAL", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAN", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGA1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMPR2", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH11", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H1", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS8", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HEBP2", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK2", "HOOK3", "HP1BP3", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "ISCA2", "ISG20L2", "ISOC1", "IST1", "ISY1", "ITCH", "ITGA6", "ITGB1", "ITM2B", "ITPRIP", "ITSN2", "IVD", "JAGN1", "JMJD6", "JUP", "KANSL3", "KARS", "KAT7", "KCMF1", "KCTD10", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIN", "KLC1", "KLC2", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIG4", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTS2", "M6PR", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MALT1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP7D3", "MAP9", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METTL1", "METTL13", "METTL3", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKLN1", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MVB12A", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NEO1", "NES", "NF1", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NMD3", "NME1", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA1", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN3", "NSUN5", "NT5C3A", "NTHL1", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT21", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OIP5", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PANX1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHIP", "PHKA1", "PHKB", "PHPT1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCD3", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POM121C", "PON2", "POP1", "POP7", "POR", "PPA2", "PPAN", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPN1", "PTPN13", "PTPN9", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RMND1", "RMND5A", "RNASEH2A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD1", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDE2", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGSH", "SGTA", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT2", "SHOC2", "SHPRH", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLK", "SMAD4", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAP47", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF10", "TAF2", "TAF6L", "TAMM41", "TAP1", "TAP2", "TARDBP", "TARS2", "TBC1D10A", "TBC1D24", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCP11L1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX2", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "TGS1", "THADA", "THAP11", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE3", "TLK2", "TLN1", "TM7SF2", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM56", "TRIO", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT112", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TTC1", "TTC19", "TTC37", "TTF2", "TTI1", "TTI2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE3D", "UBE4A", "UBE4B", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGGT1", "UHRF1", "ULK3", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "USE1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP32", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS11", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS52", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR41", "WDR43", "WDR46", "WDR48", "WDR5", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WDR92", "WFS1", "WIPI2", "WIZ", "WLS", "WRAP53", "WRAP73", "WRN", "WTAP", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YES1", "YIF1A", "YIF1B", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC11", "ZCCHC8", "ZDHHC13", "ZDHHC20", "ZFAND1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZNF207", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCC1", "ABCD3", "ABCD4", "ABHD10", "ABHD12", "ACADVL", "ACAP2", "ACAT2", "ACBD5", "ACOX3", "ACP2", "ACP6", "ACSL6", "ACTN1", "ACVR1B", "ADA", "ADPGK", "AGK", "AGPAT5", "AGPS", "AK3", "ALDH3A2", "ALG1", "ALG11", "ANKLE2", "ANO6", "AP1S1", "AP2A1", "AP2B1", "AP2M1", "AP2S1", "AP3S1", "AP5M1", "APOL2", "APOO", "APOOL", "APP", "ARFIP1", "ARFIP2", "ARID1A", "ARL6IP1", "ARL6IP5", "ASAH1", "ASNA1", "ATAD1", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V1B2", "ATP6V1E1", "ATP7B", "ATPAF1", "AURKB", "B4GAT1", "BAG5", "BAIAP2", "BAZ1B", "BCAP31", "BCKDHA", "BCKDK", "BCL2L13", "BCS1L", "BNIP1", "BRI3BP", "BSG", "BTF3", "C12orf73", "C19orf70", "C1QBP", "CADM1", "CALU", "CANX", "CBX2", "CCDC22", "CCDC47", "CCDC51", "CCNK", "CD47", "CDH2", "CDIPT", "CDK12", "CDK5RAP2", "CDKAL1", "CERS1", "CERS2", "CERS5", "CETN2", "CHCHD3", "CHID1", "CHST14", "CKAP4", "CKMT1A*", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLN5", "CLPB", "CLPP", "CLPTM1", "CNNM4", "COA3", "COPS3", "COPS4", "COPS5", "COPS8", "COQ8A", "COX11", "COX14", "COX2", "COX4I1", "COX7A2", "COX7C", "CPOX", "CPT2", "CSGALNACT2", "CSNK1A1", "CTSA", "CYB5B", "CYB5R1", "CYC1", "CYP51A1", "DAD1", "DAGLB", "DCTN3", "DCTPP1", "DDRGK1", "DDX21", "DDX31", "DDX56", "DEGS1", "DEK", "DENND4C", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DLD", "DLG1", "DLG3", "DNAJB12", "DNAJC1", "DNAJC11", "DNAJC3", "DNM2", "DOLPP1", "DPF2", "DYM", "ECE1", "ECH1", "EHD1", "EHD4", "EI24", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EPDR1", "EPHA7", "EPHX1", "EPS15L1", "ERAP1", "ERG28", "ERGIC1", "ERGIC3", "ERLIN1", "ERMP1", "ESYT2", "ETFDH", "FADS2", "FAF2", "FAM162A", "FAM3C", "FAM8A1", "FAR1", "FAR2", "FBL", "FCGRT", "FDFT1", "FECH", "FIS1", "FKBP10", "FKBP14", "FKBP7", "FLOT1", "FLOT2", "FOXRED1", "FPGS", "GAA", "GAL", "GALNT1", "GALNT4", "GBA", "GDAP1", "GGCX", "GHDC", "GHITM", "GINS2", "GINS4", "GIPC1", "GLB1", "GLOD4", "GM2A", "GNAO1", "GNG12", "GNG5", "GOLGA5", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPR107", "GPR108", "GPR89B", "GPX8", "GSK3A", "GUSB", "HACD2", "HACD3", "HADHA", "HCCS", "HDAC2", "HDHD5", "HGS", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMGB1", "HMGCR", "HMOX1", "HMOX2", "HNRNPAB", "HOOK3", "HPS6", "HS2ST1", "HSD17B12", "HSD17B4", "HSDL1", "HSP90AA1", "HSP90AB1", "HSPA13", "HYOU1", "ICMT", "IDE", "IDH3B", "IKBIP", "ILVBL", "IMMT", "ISOC1", "ITGA6", "ITM2B", "ITPRIP", "JAGN1", "KDELR1", "KDSR", "KIAA0319L", "LAMC1", "LAMP1", "LAMP2", "LBR", "LDAH", "LETM1", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LPCAT1", "LPGAT1", "LRPAP1", "LSS", "LTA4H", "LUC7L2", "MAGT1", "MAIP1", "MAN2A1", "MAVS", "MBOAT7", "MCL1", "MCM4", "MCM7", "MCU", "MCUR1", "MEN1", "METTL7B", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGST2", "MGST3", "MIA2", "MIA3", "MICU2", "MIPEP", "MMGT1", "MOGS", "MPC2", "MPDU1", "MPV17L2", "MRPL10", "MRPL11", "MRPL13", "MRPL15", "MRPL19", "MRPL2", "MRPL22", "MRPL24", "MRPL28", "MRPL45", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS22", "MRPS25", "MRPS26", "MRPS28", "MRPS34", "MRPS7", "MRPS9", "MSMO1", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTOR", "MTX1", "MTX2", "MYDGF", "MYO1C", "MYO1D", "MYO5A", "NAGLU", "NAP1L1", "NCLN", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS6", "NDUFS7", "NEDD4", "NEFL", "NEFM", "NENF", "NNT", "NOLC1", "NOP56", "NOP58", "NPC1", "NPC2", "NPTN", "NRM", "NUBPL", "NUCB1", "NUCB2", "NUP153", "NUP210", "NUP54", "NUP98", "NUPL2", "NXF1", "OCIAD1", "OGDH", "OIP5", "OPA1", "OSBPL1A", "OSBPL9", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HB", "PABPN1", "PCID2", "PCM1", "PCYOX1", "PDE6D", "PECR", "PEX14", "PEX19", "PEX3", "PGRMC1", "PGRMC2", "PHB2", "PI4K2A", "PIGG", "PIGK", "PIGS", "PIGU", "PISD", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLXNB2", "PMPCA", "PNKP", "POFUT1", "POLRMT", "PON2", "POR", "PPP1R9B", "PPT1", "PPT2", 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28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 0.0002945129286281 0.0050059471083382 0.0079074584712167 4.998879454419144e-06 4.6546022001659224e-09 +Organic anion transmembrane transporter activity 27 33 3.724436566484471 0.0001957519236577 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 0.0006446154614051 1.0 0.5540069702818398 3.093482198747331e-05 1.4087556128817868e-08 +Active transmembrane transporter activity 45 80 3.7153526822895473 0.0002029204631137 26.354368932038835 73.12621359223301 1.313035419122872 0.3239574057550545 11.878456281473593 8.663537710607383 1.88741562841277 0.3851687956916088 0.0026147433359047 0.2385892709615066 0.0417372870857938 9.1389187433899e-05 1.2711107967617888e-06 +Molecular transducer activity 10 40 3.6567925459782753 0.0002553909069675 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 0.0050972511649459 0.0011137387665463 0.0107931558292095 0.0437013304698275 0.3586110898837424 +Anion transmembrane transporter activity 38 52 3.59643268534954 0.0003226110176384 18.594660194174757 45.61893203883495 1.6222323024349488 0.2373683627198559 9.346785472607134 6.017202751823004 1.8117646078257517 0.3183345645365742 6.231342830962232e-05 0.1144439415420409 0.0309218591397596 1.605308346352145e-06 5.8634728360682456e-12 +Steroid binding 16 24 3.5891035120274544 0.0003318170780037 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 8.351917384586974e-09 0.0014578554854312 6.003960487076143e-06 1.4110415813677268e-08 4.168705702827713e-08 +Tetrapyrrole binding 11 20 3.3994928896176813 0.0006751093515742 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 0.0003156499133045 0.0001058729477741 0.0001463124134745 3.634104334677723e-05 7.1755734872007e-06 +Active ion transmembrane transporter activity 24 45 3.302577834738473 0.0009580049662243 16.271844660194176 41.71116504854369 1.2957221273899948 0.3267733012969381 7.788084220174416 5.097264791179653 1.6571109350293016 0.3632481416270505 0.053381603202757 0.4221009213565086 0.3054095712126419 0.0019480531003061 0.0001577300193594 +Metal ion transmembrane transporter activity 12 31 3.2610007806093857 0.0011101973465228 9.563106796116504 24.67233009708738 0.8657396859235934 0.3700615753207195 4.93288923178502 4.839352380624028 1.4450904591933955 0.3424002804304004 0.0189437716961278 0.4328077398558957 0.3193106634381686 0.0024491658480459 0.0021130685204602 +Lipid binding 36 151 3.249721420458754 0.0011551810992445 30.883495145631063 138.65533980582524 0.9844637598707308 0.4289871747751645 8.92748670410201 14.760635317682617 1.446857667744565 0.4068298387995807 0.0002687629597744 0.0041839106793732 0.0009948973081233 0.0010075126633043 0.00315131031019 +Oxidoreductase activity 53 240 3.195971810322566 0.0013936072678388 52.54126213592233 227.42961165048544 0.490492706528076 0.5955656171597654 20.033606385640603 16.688970744458114 1.2909283370539455 0.4039853598071011 5.927926051653114e-07 0.0002723767788359 8.268608687453181e-06 3.211775979426706e-11 3.6065607652953603e-12 +Organic acid transmembrane transporter activity 18 23 3.1263329250159173 0.0017700104706819 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0297195507119602 1.0 0.1343256297607796 0.0777638278696584 0.0050046568906662 +Sterol binding 11 18 3.1200980089136987 0.0018079087535045 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 2.217389530367961e-06 0.0005891622795957 1.99365054739206e-05 1.804155901836249e-05 3.737211014590035e-05 +Cholesterol binding 6 14 3.041198608462868 0.0023563834230124 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 5.901391807675883e-07 0.0003415681336083 7.88024543150504e-06 4.968412313462917e-06 6.157568146168938e-05 +Proton transmembrane transporter activity 18 34 3.0103098864563584 0.0026098127123941 12.769417475728156 35.478155339805824 1.2352045534927034 0.2879171268332734 5.319202861157036 2.7149368379617917 1.7021108079122016 0.3308025072902738 0.1356467821116461 0.045540604112063 0.1537720949657743 0.0309574270408548 9.29832539918378e-06 +Secondary active transmembrane transporter activity 18 24 2.9674926474090526 0.0030023946340216 9.080097087378642 21.490291262135923 1.2627683473613005 0.2947710034053126 5.466215032972134 3.0675886156990426 1.4241587428281404 0.3340388164945335 0.4507547556737884 1.0 0.5665915586776608 0.156372016851183 0.0250776393992836 +Alcohol binding 6 18 2.944882785597013 0.0032307703219212 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 2.1646660609841717e-05 0.0015459220949396 0.0001009767857935 0.0001627118516791 0.0005462267667035 +Nucleobase containing compound transmembrane transporter activity 11 16 2.896435639380728 0.0037742805244351 6.529126213592233 14.04126213592233 1.4296604886183193 0.212054291115069 3.2696940585469636 1.915888183904924 1.3255809572534116 0.2748813593420038 1.5162703458020198e-05 1.0 0.2615377882636782 7.888180780148275e-06 1.243779110187988e-08 +Passive transmembrane transporter activity 15 35 2.891336809032007 0.0038360676084168 10.728155339805824 34.00242718446602 0.8598494327527568 0.3171523987434088 5.464704354730218 4.259483301090722 1.5882390061019254 0.3339692919660049 0.1344616100398384 0.0154488277070986 0.0224300139011777 0.0539446143143092 0.0010962019851663 +Nucleotide transmembrane transporter activity 11 14 2.8853981057194784 0.0039091898252172 5.606796116504855 12.029126213592232 1.4217258291760082 0.2036087501116975 3.0234925518113496 1.8899648667798992 1.291115513359647 0.2666064512499804 1.0630692999411762e-06 1.0 0.1803331870597798 3.406519186320412e-07 2.632066428681853e-11 +Organophosphate ester transmembrane transporter activity 11 14 2.8853981057194784 0.0039091898252172 5.665048543689321 12.143203883495143 1.4298365636921646 0.2056324024803549 3.029697948284232 1.927415248708952 1.2819429632405106 0.2680490563295835 1.4408880535572852e-06 1.0 0.1880666528119386 4.895749613507748e-07 5.540083980929433e-11 +Primary active transmembrane transporter activity 29 57 2.867128602444548 0.0041421465741908 17.696601941747574 52.529126213592235 1.0080198242353189 0.3544097082146772 7.649017203625277 6.455721193615876 1.66885648871365 0.3767837436492733 0.0010931499781394 0.1055426927989023 0.0264704374304273 0.0001275668452724 1.5589670130372806e-05 +Protein transporter activity 7 15 2.859099169095475 0.0042484594768965 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 5.812529742110397e-05 0.0001966513360574 0.0016008508165985 2.0375730868266356e-05 1.407612233553433e-05 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 9 35 2.850420887627037 0.0043661410535176 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.0222360026722403 0.008915334119445 0.0113843221380013 0.0016087143668907 0.013566502730179 +Electron transfer activity 15 55 2.835968917694369 0.0045686892117386 14.919902912621358 52.12621359223301 0.5312195787834075 0.4459804256520286 6.65997259318913 4.498499451328372 1.405540355221493 0.3721784721862224 0.0076006676011307 0.0108633849741065 0.0145498805195378 0.0001254001209365 4.827935392450616e-06 +Exopeptidase activity 9 35 2.78505557943682 0.0053518548664033 9.74514563106796 31.84223300970874 1.193034763402526 0.2308543476384821 3.0338864063053523 1.9513159274241312 1.6646797512653713 0.2911825093455628 8.06047962028845e-05 0.2462339839987873 0.0025553585526862 1.2179838074162096e-05 0.0001328154988147 +Glycolipid binding 7 10 2.764066771587926 0.0057085856344825 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 7.572639894278512e-06 1.0 0.0108829135912838 1.6702585542338638e-06 4.45201220836179e-07 +Lipid transporter activity 10 21 2.760775220278504 0.0057664349150059 6.546116504854369 19.805825242718445 0.7389006587243017 0.301332987440896 3.074370954053146 3.741159812966952 1.4134673193588587 0.2984913911167897 0.0439023349013815 1.0 0.1636927349188979 0.1101174716568845 0.0309914658306075 +Oxidoreduction driven active transmembrane transporter activity 10 31 2.698080638567374 0.0069740544949594 9.733009708737864 29.83252427184466 0.7626445826297276 0.3795490924215395 4.629116134249794 3.4519743101246267 1.4198222355288384 0.35536187545778 0.004233881602233 0.0330078204264017 0.0205010816622888 0.0006293272855757 3.182120313690259e-05 +Serine hydrolase activity 7 19 2.678339640500004 0.0073988151062118 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 0.0013597282838939 0.1993158438352355 0.0010457638608999 0.000894782262763 0.0018554206644335 +Macromolecule transmembrane transporter activity 5 12 2.6305279280753915 0.008525236460994 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.0003348720906127 9.905963195641525e-05 0.0008209706516698 0.0011116174795585 0.0002599861644489 +Monooxygenase activity 5 10 2.6156237500643384 0.008906464033981 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 8.588426588809346e-05 0.0002484775908529 0.000109699640749 3.2726981844980405e-05 0.0014907402420661 +Protein transmembrane transporter activity 5 11 2.5963833611617497 0.0094210886034944 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 0.0001712958304139 5.966461606118925e-05 0.000499833948772 0.0005775014694085 9.39166481969502e-05 +Phosphatidylcholine binding 2 8 2.5495814238650683 0.0107852322686192 2.2524271844660193 7.929611650485437 1.2697801287388335 0.1567893034984199 1.081337239384838 1.04388968498945 1.4953842980517238 0.2256102823610289 0.0023996235659409 4.92948696733527e-05 0.0004144497686355 0.0058828678879826 0.0387298255956614 +Purine nucleotide transmembrane transporter activity 8 11 2.477374052304006 0.0132353112033958 4.334951456310679 9.441747572815531 0.9917737457277228 0.2833655940290197 2.4104227054611673 1.6217588601139772 1.262135146193827 0.3001583617421954 0.0023996235659409 1.0 1.0 0.0004499506622467 1.0762089436652486e-08 +Antiporter activity 10 12 2.46755380334812 0.0136039775437821 4.621359223300971 10.405339805825244 1.056576117278179 0.2813324268221227 2.679901841610502 1.304685592846984 1.2558310293487471 0.3063102364368053 0.493566892006397 1.0 1.0 0.236499214653901 0.0022852196419379 +Carbohydrate derivative transmembrane transporter activity 8 12 2.4454268147168747 0.0144680808872645 4.672330097087379 10.12135922330097 1.0096229459917263 0.2944050311743799 2.686158589641687 1.471354338494036 1.2935479322863277 0.3146313980204608 0.0098192787047171 1.0 1.0 0.0030679298819029 1.907673106738708e-06 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 6 14 2.4379349763169 0.0147714307940534 3.8398058252427183 12.78883495145631 0.8288316105774708 0.2715528044153261 1.786836430207192 1.277729935586139 1.1940635938633195 0.228034100916913 0.0005877826420502 1.0 0.001249562324504 0.000171368540682 7.09656144192021e-05 +Lamin binding 5 9 2.3967790481121884 0.0165398940457375 3.174757281553398 8.133495145631068 0.8401140072225439 0.3634406451484216 1.8429987407927015 0.9675032512806204 0.9823145131994128 0.293984725882831 0.230001661410733 1.0 1.0 0.004864195908138 4.124560666254861e-05 +Quaternary ammonium group binding 2 13 2.3957851530813947 0.0165848083573438 2.8567961165048543 12.12864077669903 0.9707568143407772 0.2573327609820879 1.4849985868988949 1.260087490061347 1.304146106648176 0.2795917987269193 0.0061166095761946 0.000132954444525 0.0010940068356494 0.0145721558996701 0.0193421266882966 +O acyltransferase activity 6 11 2.3884092447979284 0.0169214870959268 4.711165048543689 12.395631067961164 0.9877600518928406 0.2684789023147002 2.6842893514436073 2.3496085895491885 1.2379749168209273 0.2720543739153138 0.0173741699240328 0.1376340872498759 0.0362367738259921 0.0066039089173338 0.0006688519907534 +Hexosyltransferase activity 10 37 2.368424383024055 0.0178640316832552 9.633495145631068 33.87864077669903 0.7349501031127185 0.3949358882560483 4.261380470236419 4.330948695045228 1.2646745007039175 0.3422146027467064 0.5890171175292234 1.0 0.6619281210011395 0.0056900283119864 0.0209598248095547 +Atp transmembrane transporter activity 6 7 2.3245850045672123 0.0200941613952863 3.058252427184466 5.456310679611651 0.5680189081478334 0.3318090311699867 1.598392655736251 0.6936144116307477 1.3025695117924114 0.3140848719976767 0.0077477002373928 1.0 1.0 0.0006770655215996 4.357674644621987e-09 +Ceramide binding 4 5 2.312635576681617 0.0207426837811013 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 1.6659473755238268e-06 0.0015706319822673 0.0002160518736796 7.961542139625436e-06 0.0002343739811342 +Oxidoreductase activity acting on the ch ch group of donors 10 29 2.310755576514833 0.0208463595281909 7.567961165048544 28.033980582524272 0.602739632464327 0.3658961640745555 3.3714596992024415 2.798024733162656 1.2394975779858992 0.2994161584769358 0.0099347327982874 1.0 0.0108990791164035 0.0009997126365417 1.560579945741357e-05 +Inorganic anion transmembrane transporter activity 10 23 2.267416477195874 0.0233647958654463 7.427184466019417 19.274271844660195 1.0921593405593897 0.2441056926448881 3.717191605498929 3.7816647851785734 1.4014196343960104 0.2816216967014333 0.0121991568151097 0.0238262610416272 0.0128121267632092 0.0013718552613534 0.0001532284875525 +Sphingolipid binding 4 7 2.2515965407723666 0.024347779869474 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 1.0339158095414144e-05 0.0030359610091143 0.0005957185628407 4.808542268366563e-05 0.0001351923976465 +Atpase coupled transmembrane transporter activity 15 26 2.225013732334509 0.0260803162907519 8.072815533980583 22.696601941747577 0.8561067713091313 0.3392846662603397 4.166386392056555 3.892074110340729 1.3163009809214623 0.3229730128136945 0.0783748786893149 1.0 0.4231831300186898 0.0484766154729776 0.0587745096161565 +Phosphatidylserine binding 1 10 2.2249390133621354 0.0260853325413368 2.029126213592233 10.060679611650484 0.6615116985008255 0.3340719518205703 1.5854698894895154 0.9597266622759548 1.1646704221215245 0.2873190862432436 0.0836111976117339 0.0072840908179961 0.0282917804799424 0.1420085194155307 0.3923613968521051 +Transition metal ion transmembrane transporter activity 3 5 2.2199355341005416 0.0264231439713154 2.2597087378640777 4.444174757281553 1.267846808399692 0.205487024774009 1.5353529408674886 1.9618423203326616 1.2931295194130703 0.2516620757205828 0.0006959080837836 0.1050728360238821 0.2033176172301104 0.0022630844960047 0.0260591762772921 +Phospholipid binding 14 94 2.202473601658858 0.0276318718456327 18.890776699029125 88.4635922330097 0.777309720287493 0.452120200534915 6.970479526806733 10.51702894240924 1.1988133109990275 0.3785217149858343 0.0364653228581277 0.0122333161436717 0.0236160299114264 0.1050237306808948 0.2844211089274872 +Sterol transporter activity 5 9 2.199687578941812 0.0278290686656981 2.621359223300971 8.364077669902912 0.5454888897585024 0.2973249899153176 1.425267849835305 1.6080715320593837 1.318674977748992 0.2709274408896192 0.0069459336161985 1.0 0.195727907115695 0.0164697860130212 0.0225482630910853 +Serine type exopeptidase activity 4 7 2.198829305924406 0.027890061852599 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 0.0003934603131919 1.0 0.0030253365932515 3.5518765373642734e-05 2.6949933129058047e-05 +Protein carrier chaperone 6 10 2.1932857549621194 0.0282867973264664 3.3980582524271843 10.118932038834952 0.8288787693114796 0.3398938251553178 1.8569721980092944 2.0920401213092656 1.1849901066971258 0.3127406939001886 0.2692522225630656 0.0798652174269664 0.1566927560007753 0.0668959947775429 0.0094142249651338 +Glucosyltransferase activity 1 10 2.1926472985150727 0.028332800532026 2.342233009708738 9.048543689320388 0.4761205412145978 0.5159240070556952 1.9500716601415085 1.525693480881991 0.8525181118658677 0.3136461905246437 0.0378207561175528 1.0 0.1566927560007753 0.0668959947775429 0.2133837897484068 +Lipase activity 6 17 2.1865459465109267 0.0287756870250128 4.160194174757281 17.95145631067961 -0.3883889220249866 0.2447386375427953 2.2541370727794456 2.684470408535888 1.602380040893784 0.2433104127648577 0.0186961014902875 0.0301263989446325 0.0179803241310036 0.0510731923964723 0.0222951690304878 +Amino acid transmembrane transporter activity 9 12 2.175034419562448 0.0296275371735583 4.325242718446602 10.521844660194176 0.9562493229862624 0.2921494362491497 2.574340086864074 1.34633933573134 1.106576767449958 0.2884960270895668 0.502342340158651 1.0 0.3155444220122531 0.6181414355057374 0.1240743533209934 +Metalloexopeptidase activity 4 22 2.1476766105623577 0.031739454696946 5.395631067961165 20.067961165048544 0.9825976981990544 0.3457114951896768 2.1791777953827336 1.4039620491256346 0.996651753778752 0.2995335114577974 0.0029585779551093 0.1495431827221669 0.0426903814680922 0.0013109740347349 0.0059055963574577 +L amino acid transmembrane transporter activity 7 9 2.1457485138211645 0.0318930483417416 3.628640776699029 8.201456310679612 0.919975936290114 0.2876791162304417 2.2759730869054327 1.0290432051153906 1.15482978403653 0.2925518180165951 0.3968926535471839 1.0 0.2402159343378795 0.5022110525395543 0.1610434863229046 +Exogenous protein binding 4 16 2.144896628430777 0.0319611128760211 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 0.042285212020163 0.0181544170345696 0.0668951919761703 0.0215529467605083 0.0633296250195141 +Sodium ion transmembrane transporter activity 6 9 2.137240020498524 0.0325784745003012 3.033980582524272 6.733009708737864 0.6330876716410718 0.3951789521880264 1.773267150762252 1.4834287460359985 1.0827590126064015 0.3202441368223486 0.502342340158651 1.0 0.3155444220122531 0.2453334774508567 0.0413463237345707 +Voltage gated anion channel activity 5 7 2.0787206566063308 0.0376430332346642 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 0.0121723982982892 0.0009141595337786 0.0037585377466438 0.0014005858473499 5.177174829283688e-05 +Vitamin transmembrane transporter activity 5 7 2.064810316328633 0.0389409513655742 2.7766990291262137 6.252427184466019 1.4438342367310928 0.182339474606115 1.52603324115363 1.3650879028699858 1.0282691527982806 0.2346378729908682 0.0002715360113886 1.0 0.16464692140167 0.0009060327870608 0.0001896257007941 +Anion channel activity 7 13 2.060116398817269 0.0393874145248078 4.20873786407767 11.21116504854369 1.03959259790327 0.2192420598609839 2.3076742714116403 2.0905640066649145 1.3937691950814175 0.2662450395835827 0.0120652542122147 0.0072840908179961 0.0022340937067336 0.0040488107890766 0.0002780195045216 +Snap receptor activity 9 17 2.053250342625517 0.0400483041908688 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 0.1161779578639089 1.0 0.275422289319612 0.1927267877862009 0.0001611901539863 +Serine type carboxypeptidase activity 3 5 2.043261693988567 0.0410265394219133 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 0.0028631449281781 1.0 0.0008612898910877 0.0001274911609059 2.53552831216742e-05 +Sulfur compound transmembrane transporter activity 3 6 2.021024083583393 0.0432772720745913 2.9635922330097086 6.752427184466019 1.4746434057995097 0.1672652154050841 1.7026919602194592 1.5538455059459366 1.0954441166028872 0.2266277553273111 0.0014543884916538 1.0 0.2402159343378795 0.004610467719412 0.0483158324013505 +Acylglycerol o acyltransferase activity 4 6 2.0142996744904726 0.0439780801323939 2.6601941747572817 6.820388349514563 0.8174935736497821 0.2734948556707107 1.708365471336677 1.514259678343348 1.2372108727630755 0.2654117957889352 0.0053496369295055 0.092554689717322 0.0163998244725808 0.0013478250121693 0.002692648903577 +Wide pore channel activity 3 5 2.0133559084872243 0.0440772005877569 2.157766990291262 4.266990291262136 1.156945559067054 0.1661436788367006 1.073449599559222 0.4792567768515825 1.4176309163665306 0.2377490100494037 0.0077477002373928 0.000572166618939 0.0023675323812222 0.0006770655215996 0.0003159986655096 +Membrane insertase activity 5 7 2.0033183292518086 0.0451431313400725 2.737864077669903 7.388349514563107 0.8099367695235317 0.306513025583228 1.5809003521008822 1.7333564146948666 1.2685525479217892 0.3048480656363501 0.2164578169597442 0.0626754461774391 0.1241196507421894 0.0423153882822146 0.0035872092776678 +Adp transmembrane transporter activity 4 5 1.9960124045218912 0.0459325726016865 2.3689320388349513 4.201456310679611 0.5019942413211786 0.3489879061320977 1.2147179245232118 0.4188493432764195 1.248361495348926 0.3086395860172816 0.0833954900498324 1.0 1.0 0.0053511077329156 2.5140092208675777e-07 +Antigen binding 5 9 1.99566544954408 0.0459703502334649 2.504854368932039 6.936893203883495 1.1926555941065955 0.2669458193807861 1.6287691845260013 1.3674077446215156 0.9067202373946956 0.2605304200525402 0.3302973601223983 1.0 0.195727907115695 0.4248286628842983 0.0225482630910853 +Abc type transporter activity 6 9 1.9807644703807652 0.0476176929746696 3.0194174757281553 7.652912621359223 0.9831250219385844 0.2361571806590424 1.9482657586917436 2.350049836723345 1.2743804993059251 0.258194993176919 0.0685959008552041 1.0 0.2108364442764713 0.1179126451543179 0.1162251283724108 +Peptide antigen binding 5 7 1.980725211327292 0.047622097866331 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 0.230001661410733 1.0 0.1323778037089543 0.3027182369322541 0.0047081007231922 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..95b3c43697e39a5d0fb4eaf22fb6c03cb51a5f17 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 1417, + "title": "Average number of proteins per term", + "value": 17.774876499647142 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b99384f99d03a0353f4d5ee16e8987039c1ba97c --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..271fc85aa8d6d85b8ac017f5c2a90a94ff96102f --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,385 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter activity 0.6731039718332869 5.963607211301155 2.467294354561771e-09 3.4961499945974167e-06 3.49615610183103e-06 186 O60830,Q9NS69,P53007,Q99595,Q8N4V1,P28288,P21796,Q9H2J7,P45880,O75964,Q8WTV0,O43676,Q9UDW1,Q70HW3,P08183,Q14849,Q9C0H2,O43772,P04062,Q9BSK2,P03886,Q96QD8,Q8TB61,Q9HC07,Q9H2D1,Q9UBX3,O15173,Q9HD20,P30536,P38435,Q9HC21,Q86VD7,P35670,Q5SR56,O15118,P13073,Q8IUH4,O14925,Q9Y6M9,Q6KCM7,Q8IXU6,Q14728,P16615,Q9Y277,Q9Y6M7,Q9UM00,P00403,Q13423,Q9P0J0,Q9Y5J6,P12236,P17900,Q93050,Q07820,Q6P4A7,P08574,O96008,Q96ER9,O95202,Q6P4Q7,O95168,P30825,P51970,O96000,O95563,P24539,P05023,O43808,Q8NHS3,Q7L0J3,P0CG08,Q96S66,Q6NUK1,P12235,P05141,O14678,O43681,Q96NB2,Q92581,Q4KMQ2,P56385,O75947,O75380,Q9UJS0,P61916,P41440,Q96SU4,Q9BXW6,P51790,P06576,Q03519 91 +Ion transmembrane transporter activity 0.6662355147511998 4.984066067490846 6.226180447929605e-07 0.0008818609759821 0.0004411248847365 110 P53007,Q9HC21,Q86VD7,Q8N4V1,Q93050,P21796,P0CG08,P35670,P45880,Q96S66,O75964,P13073,Q8IUH4,Q6NUK1,P12235,Q6P4A7,P05141,P08574,Q6KCM7,O43681,Q9UDW1,Q70HW3,Q96ER9,Q96NB2,O95202,Q6P4Q7,Q14728,P30825,Q92581,Q4KMQ2,P56385,Q9C0H2,P16615,O43772,Q9Y277,O95563,O75947,Q9Y6M7,Q9UM00,P24539,Q96QD8,Q9UJS0,P00403,P05023,Q13423,P41440,O43808,Q8TB61,P06576,Q9HC07,Q9H2D1,P12236,Q9UBX3,P51790,Q9HD20 55 +Cation transmembrane transporter activity 0.6653530564089591 4.133580336399939 3.571553733316968e-05 0.0493504775668948 0.0015815286375344 76 P36542,Q9HC21,Q86VD7,Q8N4V1,Q93050,P35670,Q9H2J7,Q9H0U3,P13073,O75964,Q8IUH4,P12235,P05141,P56134,P08574,P36543,Q9UDW1,Q70HW3,Q96ER9,Q96NB2,O95202,Q6P4Q7,P30825,Q92581,Q4KMQ2,P56385,P16615,O43772,O75947,Q9Y6M7,Q9UM00,P24539,Q96QD8,Q9HD20,P00403,P05023,Q13423,Q9Y619,O43808,Q9HC07,P51790,P06576,Q8WWI5 43 +Inorganic molecular entity transmembrane transporter activity 0.6369720904825057 4.087120925572606 4.367594959053811e-05 0.060013882210001 0.0016726708262106 82 Q99797,P36542,P0CG08,Q8N4V1,Q93050,P21796,Q9H2J7,P45880,P35670,Q9H0U3,Q96S66,O75964,P13073,P33527,Q8IUH4,P12235,P05141,P56134,P08574,O43681,P36543,Q9UDW1,P08195,Q96ER9,O95202,Q6P4Q7,Q92581,Q4KMQ2,P56385,Q9C0H2,P16615,Q9Y277,O75947,Q9Y6M7,Q02978,Q9UM00,P24539,Q96QD8,P00403,P05023,Q13423,P06576,Q9HC07,Q9UBX3,P51790,Q9HD20 46 +Organic anion transmembrane transporter activity 0.7397287705297221 3.7244365664844703 0.0001957519236577 0.2422544443446342 0.0039122597213264 33 P53007,Q9HC21,Q86VD7,Q6NUK1,P33527,P12235,P05141,Q6KCM7,P08195,Q96NB2,Q14728,P30825,O75746,O95563,Q9Y6M7,Q02978,Q9UJS0,Q96QD8,P53985,P41440,Q9Y619,O43808,Q8TB61,Q9H2D1,Q9H9B4,P12236,Q9UBX3 27 +Active transmembrane transporter activity 0.6040963140971158 3.7153526822895473 0.0002029204631137 0.2499140461473277 0.0039935874476695 80 P53007,P28288,Q9H2J7,P35670,Q03518,P13073,P33527,P12235,O43674,P05141,O43676,Q9Y6M9,P08574,O14678,P36543,Q9UDW1,P08195,O95202,P08183,O95168,P51970,Q92581,P51798,P16615,Q15388,O96000,Q9Y6M7,P03886,Q02978,O75380,Q16795,Q96QD8,P00403,P53985,P05023,P41440,P06576,Q9P0J0,P12236,Q9UBX3,P51790,P20020,O75251,Q9HD20,Q03519 45 +Molecular transducer activity 0.6976900461195497 3.6567925459782753 0.0002553909069675 0.3036724660672381 0.0046114243112471 40 Q14108,P36896,P22466,Q9NRA0,Q9BUN8,O15173,Q15629,P30536,Q8WTV0,Q99720 10 +Anion transmembrane transporter activity 0.6663013731448068 3.59643268534954 0.0003226110176384 0.3669548719409901 0.0051742021103548 52 P53007,Q9HC21,Q86VD7,P0CG08,P21796,P45880,Q96S66,P33527,Q6NUK1,P12235,P05141,Q6KCM7,O43681,P08195,Q96NB2,Q14728,P30825,Q92581,Q4KMQ2,P51798,Q9C0H2,O75746,O95563,Q9Y277,Q9Y6M7,Q02978,Q9UJS0,Q96QD8,P53985,P41440,Q9Y619,O43808,Q8TB61,Q9H2D1,Q9H9B4,P12236,Q9UBX3,P51790 38 +Steroid binding 0.8109088972466226 3.5891035120274544 0.0003318170780037 0.375161976019424 0.0052242755503484 24 P61916,P05023,Q14108,Q96SU4,P21796,P04062,O00264,O95772,P45880,O15118,Q9BXW6,O15173,P30536,Q12770,Q14849,P38435 16 +Tetrapyrrole binding 0.8280650615790952 3.3994928896176813 0.0006751093515742 0.6159386645835745 0.0089404668334642 20 P09601,O43169,P08574,Q9H7Z7,O00264,P30519,O15173,Q16850,Q9NRV9,Q6UW02,Q8WUJ1 11 +Active ion transmembrane transporter activity 0.6405776295731381 3.302577834738473 0.0009580049662243 0.7428623399475262 0.0112189507201643 45 P53007,P35670,Q9H2J7,P13073,P33527,P12235,P05141,P08574,P36543,Q9UDW1,P08195,O95202,Q92581,P16615,Q9Y6M7,Q02978,Q9HD20,Q96QD8,P00403,P05023,P41440,P12236,P51790,P06576 24 +Metal ion transmembrane transporter activity 0.6916059284330279 3.2610007806093857 0.0011101973465228 0.7927902140371892 0.0126866906453457 31 P16615,Q9HC07,Q8N4V1,P35670,Q9Y6M7,Q96ER9,O95202,Q6P4Q7,Q8IUH4,Q9UM00,Q9HD20,Q96QD8 12 +Lipid binding 0.4781382773211384 3.249721420458754 0.0011551810992445 0.8056000801991658 0.0130951329410357 151 Q9BQE5,Q9NZJ7,Q14108,Q13432,P21796,P45880,O15118,Q9H490,Q9H4A6,Q8WTV0,O15254,Q8NCC3,O95772,P53367,P50897,Q12770,Q14849,Q9UM22,Q9NQZ5,O76054,P04062,O00264,O43292,O14735,A6NIH7,O60313,P05023,P61916,P07602,Q96SU4,Q99623,O15173,O14773,P30536,Q92643,P38435 36 +Oxidoreductase activity 0.4537031435465933 3.195971810322566 0.0013936072678388 0.8613938450670323 0.0151903192194438 240 P14406,O43169,P30519,Q8N0U8,Q16850,P13073,Q6UW02,Q06136,Q9UBM7,Q6NUM9,Q96LJ7,O43676,Q9Y6M9,P08574,Q9NRG7,Q53GQ0,Q9UDW1,Q16134,Q9NZ01,P21912,O00116,Q15392,P00374,O76062,O15121,Q9UHG3,O95168,Q8N4Q0,P51970,O95864,P09601,O00625,Q9H3N1,Q9H7Z7,O96000,Q6IAN0,O00767,P03886,P51648,P16435,P00403,Q13423,P49748,Q3SXM5,O95881,Q9P0J0,Q99536,Q8TED1,Q14534,Q99735,Q15800,Q14739,P40939 53 +Organic acid transmembrane transporter activity 0.744178121081684 3.1263329250159173 0.0017700104706819 0.9187583429571994 0.0187172002757932 23 P53985,P41440,O75746,Q9Y619,P53007,Q9H2D1,O95563,Q9H9B4,Q9H2J7,P08195,Q9UBX3,Q96NB2,Q02978,P33527,P08183,Q9UJS0,Q96QD8,P30825 18 +Sterol binding 0.8044755247686471 3.1200980089136987 0.0018079087535045 0.9230135044521888 0.0189763459534515 18 P61916,Q14108,Q96SU4,P21796,O95772,P45880,O15118,Q9BXW6,P30536,Q12770,Q14849 11 +Cholesterol binding 0.8525266054791358 3.041198608462868 0.0023563834230124 0.9646669141540308 0.0227142538123039 14 Q14108,P21796,O95772,P45880,P30536,Q14849 6 +Proton transmembrane transporter activity 0.62611618012105 3.0103098864563584 0.0026098127123941 0.97534902205926 0.0249871933342059 34 P05141,P56385,P00403,Q13423,P56134,P36542,P06576,P08574,Q93050,Q9UDW1,O75947,P24539,O95202,O75964,P13073,P51790,P12235,Q92581 18 +Secondary active transmembrane transporter activity 0.7060629028647754 2.9674926474090526 0.0030023946340216 0.985888887796961 0.0272717512590298 24 P53985,P05141,P51798,Q15758,P41440,P53007,P04920,Q9H2J7,P08195,Q9Y6M7,P12236,Q9UBX3,O95202,P51790,Q02978,P12235,Q96QD8,Q92581 18 +Alcohol binding 0.771733855837346 2.944882785597013 0.0032307703219212 0.98980046092897 0.0289746933301414 18 Q14108,P21796,O95772,P45880,P30536,Q14849 6 +Nucleobase containing compound transmembrane transporter activity 0.7936963702679193 2.896435639380728 0.0037742805244351 0.9952909716623608 0.0324130636553009 16 P05141,O43808,Q8TB61,Q9HC21,Q86VD7,Q9H2D1,Q6KCM7,Q9BSK2,P12236,Q6NUK1,P12235 11 +Passive transmembrane transporter activity 0.6002222417273454 2.891336809032007 0.0038360676084168 0.9956871675609674 0.0324676651913273 35 Q4KMQ2,P56385,Q9C0H2,P0CG08,Q9Y277,P21796,O96008,P45880,O75947,Q96ER9,Q96S66,O75964,P51790,Q9UM00,P24539 15 +Nucleotide transmembrane transporter activity 0.82061534032311 2.8853981057194784 0.0039091898252172 0.9961132323798656 0.0324676651913273 14 P05141,O43808,Q8TB61,Q9HC21,Q86VD7,Q9H2D1,Q6KCM7,Q9BSK2,P12236,Q6NUK1,P12235 11 +Organophosphate ester transmembrane transporter activity 0.82061534032311 2.8853981057194784 0.0039091898252172 0.9961132323798656 0.0324676651913273 14 P05141,O43808,Q8TB61,Q9HC21,Q86VD7,Q9H2D1,Q6KCM7,Q9BSK2,P12236,Q6NUK1,P12235 11 +Primary active transmembrane transporter activity 0.5682506569982799 2.867128602444548 0.0041421465741908 0.9972097145336786 0.0337323085955659 57 P28288,P35670,Q03518,P13073,P33527,O43674,O43676,P08574,O14678,Q9Y6M9,P36543,Q9UDW1,P08183,O95168,P51970,P51798,P16615,Q15388,O96000,P03886,O75380,Q16795,Q9HD20,P00403,P05023,Q9P0J0,P20020,P06576,Q03519 29 +Protein transporter activity 0.80110560409831 2.859099169095475 0.0042484594768965 0.9976014512682376 0.0344003833072138 15 O60830,Q9NS69,O14925,Q99595,Q9Y5J6,Q07820,Q9HD20 7 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5948384162896895 2.850420887627037 0.0043661410535176 0.9979713152128914 0.034757426251879 35 O95864,P09601,Q14534,P30519,Q15800,Q16850,Q6UW02,O15121,P16435 9 +Electron transfer activity 0.5677928268487432 2.835968917694369 0.0045686892117386 0.9984794243141653 0.0361666626426465 55 P14406,P00403,O43676,Q9Y6M9,P08574,Q9P0J0,Q16134,Q9UDW1,P21912,P13073,P03886,O15121,O95168,P16435,P51970 15 +Peptide receptor activity 0.9901657769036244 2.8299942959704905 0.0046548834013664 0.9986550108355852 0.036441821987493 2 Q99720 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9820174206237696 2.795865051999782 0.0051761008437225 0.9993597057997622 0.0394329833094347 2 P30519 1 +Exopeptidase activity 0.5862909544000835 2.78505557943682 0.0053518548664033 0.999501518532976 0.0403381826898591 35 P09960,O75844,Q7Z2K6,Q969V3,Q9H3G5,P55786,O14773,P42785,Q9HB40 9 +Glycolipid binding 0.8729787671408904 2.764066771587926 0.0057085856344825 0.9997001543312632 0.0423511300736215 10 Q9NZJ7,P07602,Q9UM22,P50897,O43292,O14773,Q92643 7 +Lipid transporter activity 0.7039328195624867 2.760775220278504 0.0057664349150059 0.9997238836202692 0.0425574910133511 21 P61916,Q4KMQ2,P30536,Q96SU4,O14678,O15118,Q9BXW6,P17900,P08183,Q14849 10 +Lysophosphatidic acid binding 0.966844619275076 2.7319724379721984 0.0062956407438243 0.99987014898677 0.0457483227384571 2 P50897 1 +Vitamin d binding 0.9648777746558012 2.723657428138901 0.006456343692601 0.9998967440941738 0.0466767296551821 2 P04062 1 +Quaternary ammonium group transmembrane transporter activity 0.9620679966282653 2.7117658260378534 0.006692585468226 0.9999262824841928 0.0481390538501335 2 O43772 1 +Oxidoreduction driven active transmembrane transporter activity 0.6104215848639561 2.698080638567374 0.0069740544949594 0.9999506639694512 0.0496594734641083 31 P00403,O43676,Q9Y6M9,P08574,Q9P0J0,Q9UDW1,P03886,P13073,O95168,P51970 10 +Serine hydrolase activity 0.7082422696197517 2.678339640500004 0.0073988151062118 0.9999730923094652 0.0519015891361496 19 P10619,Q9H3G5,O14773,Q16740,Q9HB40,P42785,P67812 7 +Macromolecule transmembrane transporter activity 0.807319420939624 2.6305279280753915 0.008525236460994 0.9999946158340818 0.0578002873934378 12 O60830,Q9NS69,O14925,Q99595,Q07820 5 +3 hydroxyacyl coa dehydratase activity 0.9409946614217471 2.622089806639192 0.008739239880606 0.9999960347095556 0.0589690614800897 2 Q9P035 1 +Monooxygenase activity 0.8401070128071366 2.6156237500643384 0.008906464033981 0.999996877876948 0.0598126044367356 10 P09601,Q15800,P30519,Q16850,Q6UW02 5 +Protein transmembrane transporter activity 0.818248342368842 2.5963833611617497 0.0094210886034944 0.9999985043723298 0.0618040858849612 11 O60830,Q9NS69,O14925,Q99595,Q07820 5 +Phospholipase d activity 0.92891261590334 2.570285709988178 0.0101614671319261 0.9999994815668668 0.0634308322728604 2 P09601 1 +Phosphatidylcholine binding 0.8781665824476237 2.5495814238650683 0.0107852322686192 0.9999997877890736 0.0661587624443009 8 Q14108,P21796 2 +Ubiquinone binding 0.9157066591739232 2.513337466914617 0.0119594871799371 0.9999999605702364 0.071807598872758 2 P21912 1 +Azole transmembrane transporter activity 0.9109300365271108 2.4926556058689076 0.0126791760294078 0.999999985958716 0.0739357713319789 2 Q9HC21 1 +Purine nucleotide transmembrane transporter activity 0.7930684008201115 2.477374052304006 0.0132353112033958 0.9999999936806688 0.0765487182661709 11 P05141,O43808,Q8TB61,Q86VD7,Q6KCM7,P12236,Q6NUK1,P12235 8 +Antiporter activity 0.7737231492196094 2.46755380334812 0.0136039775437821 0.9999999962785724 0.0777611318915138 12 P05141,P41440,P08195,P12236,Q9UBX3,O95202,P51790,Q02978,P12235,Q92581 10 +Carbohydrate derivative transmembrane transporter activity 0.7692132485959882 2.4454268147168747 0.0144680808872645 0.9999999989250844 0.0813542484811663 12 P05141,O43808,Q8TB61,Q86VD7,Q6KCM7,P12236,Q6NUK1,P12235 8 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.732333672824025 2.4379349763169 0.0147714307940534 0.9999999993050964 0.0817621774811472 14 Q9H7Z7,Q14739,Q15392,O76062,Q9UBM7,Q8N4Q0 6 +Lamin binding 0.8088620930909718 2.3967790481121884 0.0165398940457375 0.9999999999455108 0.0896972268792224 9 P42167,Q5JTV8,Q5SNT2,Q9UH99,Q14739 5 +Quaternary ammonium group binding 0.7418886845843601 2.3957851530813947 0.0165848083573438 0.9999999999489252 0.0896972268792224 13 Q14108,P21796 2 +O acyltransferase activity 0.774482746742705 2.3884092447979284 0.0169214870959268 0.9999999999685598 0.0908248000565469 11 Q8NF37,Q9HCL2,Q8NCC3,Q92604,Q96N66,P23786 6 +Nucleobase transmembrane transporter activity 0.8831132340545089 2.3713355443417603 0.017723932291036 0.9999999999901156 0.0934071324545116 2 P12235 1 +Oxidative phosphorylation uncoupler activity 0.8831132340545089 2.3713355443417603 0.017723932291036 0.9999999999901156 0.0934071324545116 2 P12235 1 +Hexosyltransferase activity 0.5322152865500506 2.368424383024055 0.0178640316832552 0.9999999999919243 0.0934071324545116 37 Q8N4A0,Q2TAA5,Q16739,P46977,Q13126,Q8N6G5,P04062,Q6ZXV5,Q10472,Q9BT22 10 +Metal ion proton antiporter activity 0.8746838999718994 2.334277508046227 0.0195811956792022 0.9999999999993234 0.0993972677954859 2 O95202 1 +Ion gated channel activity 0.8741219443663877 2.3318021381907257 0.0197111025056679 0.9999999999994392 0.0993972677954859 2 Q9C0H2 1 +Intracellular calcium activated chloride channel activity 0.8741219443663877 2.3318021381907257 0.0197111025056679 0.9999999999994392 0.0993972677954859 2 Q9C0H2 1 +Atp transmembrane transporter activity 0.8843556555993192 2.3245850045672123 0.0200941613952863 0.9999999999996776 0.100612815184172 7 O43808,Q86VD7,Q6KCM7,P12236,Q6NUK1,P12235 6 +G protein coupled receptor activity 0.99044406970208 2.3198758429115953 0.0203475947314029 0.9999999999997766 0.101523034276049 3 Q99720,Q9NRA0 2 +Ceramide binding 0.964566929133853 2.312635576681617 0.0207426837811013 0.999999999999874 0.1025719866350525 5 Q9UM22,P45880,P21796,P07602 4 +Oxidoreductase activity acting on the ch ch group of donors 0.5718347568250054 2.310755576514833 0.0208463595281909 0.9999999999998914 0.1025719866350525 29 Q6NUM9,P49748,Q9H7Z7,Q9NZ01,P21912,Q14739,Q15392,O76062,Q9UBM7,Q8N4Q0 10 +Oxidoreductase activity acting on single donors with incorporation of molecular oxygen 0.869345321719579 2.310737180160181 0.0208473762532781 0.9999999999998916 0.1025719866350525 2 O00625 1 +Folic acid transmembrane transporter activity 0.8651306546782732 2.292114414163537 0.0218990418528699 0.9999999999999764 0.105121557301595 2 Q9H2D1 1 +Leukotriene c4 synthase activity 0.8645686990727705 2.28962883303116 0.0220428420922962 0.9999999999999808 0.1051673644605513 2 Q99735 1 +Inorganic anion transmembrane transporter activity 0.6060640407711427 2.267416477195874 0.0233647958654463 0.9999999999999972 0.1099930755526163 23 Q4KMQ2,Q9C0H2,P0CG08,Q9Y277,O43681,P21796,P45880,Q9Y6M7,Q9UBX3,Q96S66 10 +Peptide hormone binding 0.8589491430176965 2.2647401850518913 0.0235286279399384 0.9999999999999978 0.110397568844016 2 P42892 1 +Sphingolipid binding 0.8668652509578436 2.2515965407723666 0.024347779869474 0.9999999999999992 0.11274772573544 7 Q9UM22,P45880,P21796,P07602 4 +Amino acid sodium symporter activity 0.8522056757516074 2.23479534767627 0.0254307874285839 1.0 0.1162433089880757 2 Q96QD8 1 +Organic acid sodium symporter activity 0.8522056757516074 2.23479534767627 0.0254307874285839 1.0 0.1162433089880757 2 Q96QD8 1 +Tap1 binding 0.8502388311323394 2.2260453989828535 0.026011140650751 1.0 0.1173425911462675 2 Q03519 1 +Atpase coupled transmembrane transporter activity 0.5791054323855874 2.225013732334509 0.0260803162907519 1.0 0.1173425911462675 26 P05023,P51798,P16615,Q15388,P06576,P28288,O14678,P36543,P35670,Q03518,P20020,P33527,P08183,Q9HD20,Q03519 15 +Phosphatidylserine binding 0.7563970916403231 2.2249390133621354 0.0260853325413368 1.0 0.1173425911462675 10 Q14108 1 +Transition metal ion transmembrane transporter activity 0.9406623090367402 2.2199355341005416 0.0264231439713154 1.0 0.117979472130054 5 Q9HD20,Q9HC07,Q8N4V1 3 +Ganglioside binding 0.9640247329960656 2.2179249247109416 0.0265599517357002 1.0 0.117979472130054 3 Q9UM22,P07602 2 +Glycosphingolipid binding 0.9640247329960656 2.2179249247109416 0.0265599517357002 1.0 0.117979472130054 3 Q9UM22,P07602 2 +Phospholipid binding 0.4299974217347824 2.202473601658858 0.0276318718456327 1.0 0.1219759803862123 94 Q9NZJ7,Q14108,P07602,Q9UM22,P21796,Q8NCC3,P45880,P50897,O43292,Q92643,O14773,Q9H490,Q9H4A6,Q8WTV0 14 +Sterol transporter activity 0.7661637090023234 2.1996875789418113 0.0278290686656981 1.0 0.1219759803862123 9 P61916,Q96SU4,O15118,P30536,Q14849 5 +Serine type exopeptidase activity 0.8543099896268055 2.198829305924406 0.027890061852599 1.0 0.1219759803862123 7 Q9H3G5,P42785,Q9HB40,O14773 4 +Protein carrier chaperone 0.7497843163438926 2.1932857549621194 0.0282867973264664 1.0 0.1224011535179295 10 Q8N766,Q9P0I2,Q9NPA0,Q8N4V1,Q15070,Q5J8M3 6 +Glucosyltransferase activity 0.7496511843770345 2.1926472985150727 0.028332800532026 1.0 0.1224011535179295 10 P04062 1 +Lipase activity 0.6502319661606778 2.1865459465109267 0.0287756870250128 1.0 0.1231877598623662 17 P09601,Q8N2A8,Q8NCG7,Q8NCC3,Q9H6V9,Q8IV08 6 +Amino acid transmembrane transporter activity 0.7150581356395033 2.175034419562448 0.0296275371735583 1.0 0.1253200602236782 12 O75746,Q9Y619,Q9H9B4,Q9H2J7,P08195,Q96NB2,Q9UJS0,Q96QD8,P30825 9 +Acylglycerol lipase activity 0.837875807811179 2.170881334740018 0.0299401436144153 1.0 0.1262654270881741 2 Q8NCG7 1 +Scavenger receptor activity 0.9557454906419384 2.1618858373331027 0.0306269769198532 1.0 0.128397710933231 4 Q14108 1 +High density lipoprotein particle binding 0.9468736710535904 2.1511888308904683 0.0314612982578064 1.0 0.1299899169828904 3 Q9BQE5 1 +Metalloexopeptidase activity 0.5961789172346189 2.1476766105623577 0.031739454696946 1.0 0.1299899169828904 22 P09960,O75844,Q969V3,Q7Z2K6 4 +L amino acid transmembrane transporter activity 0.7546489132570081 2.1457485138211645 0.0318930483417416 1.0 0.1299899169828904 9 O75746,Q9Y619,Q9H9B4,P08195,Q9UJS0,Q96QD8,P30825 7 +Exogenous protein binding 0.6547893502313568 2.144896628430777 0.0319611128760211 1.0 0.1299899169828904 16 O15118,P35613,Q14108,Q8WTV0 4 +Succinate transmembrane transporter activity 0.8319752739533485 2.144453993887494 0.0319965279324456 1.0 0.1299899169828904 2 Q9UBX3 1 +Sulfate transmembrane transporter activity 0.8319752739533485 2.144453993887494 0.0319965279324456 1.0 0.1299899169828904 2 Q9UBX3 1 +Sodium ion transmembrane transporter activity 0.7528390298593054 2.1372400204985236 0.0325784745003012 1.0 0.1300385869490898 9 P05023,Q9H2J7,Q9Y6M7,Q6P4Q7,Q96QD8,Q92581 6 +2 acylglycerol 3 phosphate o acyltransferase activity 0.9421023046655432 2.132547141493178 0.0329618934077109 1.0 0.1308319410608582 3 Q8NF37,Q96N66 2 +L ornithine transmembrane transporter activity 0.8283225625175552 2.128062512335844 0.033331900942799 1.0 0.1319310157428665 2 P30825 1 +Voltage gated anion channel activity 0.8260026435676965 2.0787206566063308 0.0376430332346642 1.0 0.1453410847234855 7 Q4KMQ2,P0CG08,Q9Y277,P21796,P45880 5 +Vitamin transmembrane transporter activity 0.8227478917349744 2.064810316328633 0.0389409513655742 1.0 0.1495374744851457 7 Q9HC21,Q9H2D1,O14678,P04062,P38435 5 +Anion channel activity 0.6771746706438104 2.060116398817269 0.0393874145248078 1.0 0.1508431523828453 13 Q4KMQ2,Q9C0H2,P0CG08,Q9Y277,P21796,P45880,Q96S66 7 +Snap receptor activity 0.6273440467719867 2.0532503426255175 0.0400483041908688 1.0 0.1525495888130674 17 Q9UEU0,Q9NZ43,Q12981,O60499,O15400,Q9P2W9,Q12846,Q5SQN1,Q86Y82 9 +Gpi anchor binding 0.921585160202361 2.0520169074676344 0.0401680192986981 1.0 0.1525795990662176 3 Q92643,O43292 2 +Manganese ion transmembrane transporter activity 0.9208278545615212 2.0490331299172904 0.0404588754504477 1.0 0.1528806040354254 3 Q9HC07 1 +Serine type carboxypeptidase activity 0.8957387794430153 2.043261693988567 0.0410265394219133 1.0 0.1544148959297994 5 Q9H3G5,P42785,Q9HB40 3 +Aromatic amino acid transmembrane transporter activity 0.8069682495082815 2.0317597490754187 0.0421779838660649 1.0 0.1564560291576292 2 P30825 1 +Calcium cation antiporter activity 0.8069682495082813 2.0317597490754165 0.0421779838660651 1.0 0.1564560291576292 2 O95202 1 +Sulfur compound transmembrane transporter activity 0.867089726747865 2.0210240835833932 0.0432772720745913 1.0 0.1601146071271433 6 Q70HW3,Q9UBX3,Q8TB61 3 +Acylglycerol o acyltransferase activity 0.8654284911881842 2.0142996744904726 0.0439780801323939 1.0 0.1610304523737659 6 Q8NF37,Q96N66,Q8NCC3,Q92604 4 +Wide pore channel activity 0.8882128816636542 2.0133559084872243 0.0440772005877569 1.0 0.1610304523737659 5 P45880,Q9Y277,P21796 3 +Atpase coupled inorganic anion transmembrane transporter activity 0.802191626861478 2.0101095955163464 0.0444195907162199 1.0 0.1618060669534283 2 P33527 1 +Porin activity 0.9156592634242284 2.006960016850448 0.0447539204836975 1.0 0.1626059110907677 4 P45880,Q9Y277,P21796 3 +Membrane insertase activity 0.8084168964782503 2.0033183292518086 0.0451431313400725 1.0 0.163099893482059 7 Q9P0I2,Q9NPA0,Q8N4V1,Q15070,Q5J8M3 5 +Lipase binding 0.7999438044394453 1.999907858900693 0.0455102143871797 1.0 0.1636750603721666 2 P30533 1 +Adp transmembrane transporter activity 0.8838582677165345 1.9960124045218912 0.0459325726016865 1.0 0.1640805699768762 5 Q86VD7,O43808,P12236,P12235 4 +Antigen binding 0.7229762883940315 1.99566544954408 0.0459703502334649 1.0 0.1640805699768762 9 P01889,P10321,Q15392,P55899,Q03519 5 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.9052838673412036 1.987615505352062 0.0468542301385488 1.0 0.1656608516830434 3 O95864,O15121 2 +Abc type transporter activity 0.7198601708781464 1.9807644703807656 0.0476176929746696 1.0 0.1665491490793876 9 P28288,O14678,Q03518,Q9HD20,P08183,Q03519 6 +Peptide antigen binding 0.803174382358115 1.980725211327292 0.047622097866331 1.0 0.1665491490793876 7 P01889,P10321,Q15392,P55899,Q03519 5 +Organic hydroxy compound transmembrane transporter activity 0.7934813149761066 1.970530615430052 0.0487775897870785 1.0 0.1689922853992428 2 Q14728 1 +Sulfotransferase activity 0.8991006183249026 1.9630930971444256 0.049635357496488 1.0 0.1715446379817648 3 P0DMN0,Q8NCH0 2 +Calcium ion binding 0.4126549263510385 1.9524965704058663 0.0508792777373408 1.0 0.1747484002263794 90 Q9Y680,Q6NUK1,P55327,P27824,Q9NWM8,Q6KCM7,O43681,O95202,Q9UBC2,Q02818,Q14257,P41208,Q96A33,O14967,Q8NF37,P16615,Q9BRK5,Q9UM22,P80303,Q9UJS0,O75071,Q9H223,O43852 23 +Fad binding 0.6856686348658234 1.949925378417927 0.0511850137929001 1.0 0.1751912187066173 11 O00116,Q14534,Q15392 3 +Organic cation transmembrane transporter activity 0.7938370875004532 1.940356277506174 0.0523364063161613 1.0 0.1778543619160411 7 Q9HC21,Q86VD7,O43772,Q70HW3 4 +Gated channel activity 0.635701398691781 1.9188558359428824 0.0550025811711556 1.0 0.1838175884894517 14 Q4KMQ2,Q9C0H2,P0CG08,Q9Y277,P21796,P45880,Q96ER9 7 +Nucleoside diphosphatase activity 0.8876776983590797 1.9176576313306808 0.0551544373556782 1.0 0.1838913829011673 3 Q86VD7 1 +Acyltransferase activity 0.4619784208483241 1.9083871456301285 0.0563411970117131 1.0 0.1860966810386888 58 Q8NF37,Q8N5B7,Q969G3,Q9HCL2,Q9NUQ2,Q5W0Z9,O75448,Q96N66,Q8NCC3,Q92604,P40939,P27544,Q96G23,Q9BWD1,Q8IUH4,O15269,P23786,Q96QD8 18 +Beta 2 microglobulin binding 0.7752177577971258 1.8871400300205932 0.0591414938140235 1.0 0.1935415628971625 2 P55899 1 +Oxidoreductase activity acting on diphenols and related substances as donors 0.8839341797484997 1.8827639466152373 0.0597323650323644 1.0 0.1945486882856128 4 Q9UDW1 1 +Ubiquinol cytochrome c reductase activity 0.8839341797484997 1.8827639466152373 0.0597323650323644 1.0 0.1945486882856128 4 Q9UDW1 1 +Sphingosine n acyltransferase activity 0.8746486790331662 1.8656292631786255 0.0620932525321333 1.0 0.1981669793649391 3 P27544,Q96G23 2 +Misfolded protein binding 0.6156820718208104 1.8617295392155655 0.0626412226797286 1.0 0.1994665450273605 15 Q6NTF9,P48723,O14656,P46379,Q9BUN8 5 +Lysophospholipid acyltransferase activity 0.8471452942573636 1.84867270805519 0.064505086852129 1.0 0.2013968788443542 5 Q8NF37,Q96N66,Q92604 3 +Symporter activity 0.6737652775424393 1.8211287664928464 0.0685872854230253 1.0 0.2108203545432255 10 P53985,Q15758,P55011,Q9H2J7,Q9Y6M7,Q9BXP2,Q96QD8 7 +Solute proton antiporter activity 0.8597526700393492 1.805889698040136 0.0709355705991607 1.0 0.2161628033097007 3 O95202,Q92581 2 +Glycosyltransferase activity 0.457237134291774 1.804857151605123 0.0710970383509494 1.0 0.2161899213375438 51 Q8N4A0,Q2TAA5,Q16739,P46977,Q13126,Q8N6G5,P04062,Q6ZXV5,P43490,Q10472,Q9BT22,Q8IXJ6 12 +Oxidoreductase activity acting on a heme group of donors 0.8338285503566281 1.7947532802344166 0.0726930174759012 1.0 0.2200983029131455 5 P16435,P13073 2 +Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity 0.7507726889575617 1.7747296638918448 0.0759425348562885 1.0 0.226797868222749 2 O43505 1 +Beta 1 3 galactosyltransferase activity 0.7507726889575617 1.7747296638918448 0.0759425348562885 1.0 0.226797868222749 2 O43505 1 +Catalytic activity acting on a glycoprotein 0.7507726889575617 1.7747296638918448 0.0759425348562885 1.0 0.226797868222749 2 O43505 1 +Aspartic endopeptidase activity intramembrane cleaving 0.8518830803822388 1.7742240197483483 0.0760261026152475 1.0 0.226797868222749 3 Q92542,Q8TCT8 2 +Metallopeptidase activity 0.4582914357226808 1.766500809384309 0.0773118659025347 1.0 0.2281349110129847 43 P14735,Q99797,Q10713,Q9UIQ6,P09960,P53582,P42892,P22695,O75844,Q9NZ08,Q969V3,Q7Z2K6,P55786,Q92905,P51665,Q96TA2 16 +Folic acid binding 0.8485730422487496 1.760884197667664 0.0782580050624905 1.0 0.2283976551990083 3 P00374 1 +Carboxypeptidase activity 0.6337331581444633 1.7527377168933975 0.0796470384130623 1.0 0.2303262314924679 12 Q9H3G5,P42785,Q9HB40 3 +Magnesium ion transmembrane transporter activity 0.8503087020097573 1.7497150431310633 0.0801674966183427 1.0 0.2309037559914129 4 Q8IUH4,Q8N4V1 2 +Quinone binding 0.8223599297894231 1.7481254648955826 0.0804423043885946 1.0 0.2309037559914129 5 Q8N0U8,P21912 2 +Prenyltransferase activity 0.8004082705822826 1.74766177573799 0.0805226114070885 1.0 0.2309037559914129 6 P37268 1 +Epoxide hydrolase activity 0.8187066359746715 1.7332363591171804 0.083053667026665 1.0 0.2342966003506326 5 P09960 1 +Ether hydrolase activity 0.8187066359746715 1.7332363591171804 0.083053667026665 1.0 0.2342966003506326 5 P09960 1 +Dicarboxylic acid transmembrane transporter activity 0.7459676909073365 1.7308949068411734 0.0834705102018507 1.0 0.2342966003506326 7 P41440,O75746,Q9UBX3,Q02978,Q9UJS0 5 +Cargo receptor activity 0.6676995264768626 1.7278629001727992 0.0840128071141106 1.0 0.2348050250112322 9 Q14108 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.8435327999057873 1.7227417379300427 0.0849352389237836 1.0 0.2369158140846484 4 Q15800,Q16850 2 +Phospholipase activity 0.5997157658053678 1.7176874991875428 0.0858536307181709 1.0 0.2385384210346044 14 P09601,Q8NCC3,Q8N2A8 3 +Nadh dehydrogenase activity 0.5172536009518014 1.7165861363449817 0.0860548173432129 1.0 0.2386295032785376 24 O43676,Q9Y6M9,Q9P0J0,P03886,O95168,P51970 6 +Amide transmembrane transporter activity 0.8143982002249673 1.7156554562973374 0.0862251220076326 1.0 0.2386347614937802 5 P41440,Q9H2D1,Q03519,Q03518 4 +Modified amino acid binding 0.5366652685450932 1.7077857630814768 0.0876761017099572 1.0 0.242030127447823 21 Q14108,Q9H7Z7,Q99735,P00374,Q8WTV0 5 +Apolipoprotein binding 0.8342892199524636 1.7031831852654882 0.0885337923769722 1.0 0.2426545141163822 3 Q8WTV0 1 +Mhc class i protein binding 0.6616232427780959 1.6979919331947677 0.0895092843606388 1.0 0.2448545481448364 9 P06576,Q9BUN8,Q03519,P51572 4 +Steroid hormone binding 0.7330710873840849 1.6928203950080254 0.0904896593594806 1.0 0.2461110313097582 2 P05023 1 +Mhc protein binding 0.645582066808804 1.679432078391799 0.093067865857207 1.0 0.2512519061290714 10 P06576,Q9BUN8,Q03519,P51572 4 +Sulfatide binding 0.8275594736677965 1.675924961497539 0.0937528916905559 1.0 0.2525624477671439 3 P50897 1 +Hydrolase activity acting on ether bonds 0.7331669267385394 1.674212273993002 0.0940888881044035 1.0 0.2526641711051862 7 P09960 1 +Cation channel activity 0.5371921889454436 1.6706532883046468 0.094790180390665 1.0 0.2539086684566584 20 Q4KMQ2,P56385,P36542,O75947,Q96ER9,O75964,P06576,Q9UM00,P24539 9 +Palmitoyltransferase activity 0.7285304008654853 1.6536165557241136 0.0982054466856106 1.0 0.2610827728958916 7 Q5W0Z9,P23786,Q8IUH4 3 +Solute cation symporter activity 0.6784686676325377 1.6450638468964918 0.0999566451590938 1.0 0.2638227574905497 8 Q9Y6M7,Q96QD8 2 +Acetylgalactosaminyltransferase activity 0.7962016409002368 1.6411537570936796 0.1007655021128086 1.0 0.2644161416552775 5 Q8N4A0,Q10472 2 +Oxidoreductase activity acting on nad p h 0.4639266783282998 1.626143822868183 0.1039190634327413 1.0 0.2672473918043457 32 Q13423,O43676,Q9Y6M9,Q9P0J0,P03886,O95168,P16435,P51970 8 +Xenobiotic transmembrane transporter activity 0.8139404159640276 1.6206308482092475 0.1050968322794347 1.0 0.2683283087206493 3 P41440,P08183 2 +Modified amino acid transmembrane transporter activity 0.8139404159640276 1.6206308482092475 0.1050968322794347 1.0 0.2683283087206493 3 P41440,Q9H2D1 2 +Peptide transmembrane transporter activity 0.8139404159640267 1.6206308482092435 0.1050968322794356 1.0 0.2683283087206493 3 Q03519,Q03518 2 +Palmitoyl protein hydrolase activity 0.7909340276969411 1.619515106976418 0.1053364787387489 1.0 0.268456457505049 5 Q9NUJ1,Q9UMR5,P50897 3 +Sterol transfer activity 0.817361717043761 1.6181003576802315 0.1056409714542123 1.0 0.2687491140944684 4 P30536,Q14849 2 +Proton transporting atp synthase activity rotational mechanism 0.6328151227870925 1.6146340675836588 0.1063899633296396 1.0 0.269686186114668 10 P56385,P36542,O75947,O75964,P06576,P24539 6 +Proton channel activity 0.6328151227870925 1.6146340675836588 0.1063899633296396 1.0 0.269686186114668 10 P56385,P36542,O75947,O75964,P06576,P24539 6 +P type transmembrane transporter activity 0.7193412336438516 1.6126997993361762 0.1068097441751065 1.0 0.270266799100225 7 P16615,P35670 2 +P type potassium transmembrane transporter activity 0.7142455745995935 1.6053115102791355 0.1084252673465648 1.0 0.2733782986300399 2 P05023 1 +Amide binding 0.3693700107763618 1.5985400863740924 0.1099228315118523 1.0 0.274463314884835 113 Q9NZJ7,P30533,Q9Y680,P01889,P21796,P45880,P10321,Q03518,P55899,Q8WTV0,P24390,P55786,Q9Y3C6,Q15392,P00374,Q9UM22,Q9H7Z7,O00264,P41440,P49748,P14735,P07602,P42892,Q99735,Q99623,O14773,P40939,Q03519,Q9Y287 29 +Udp glycosyltransferase activity 0.5316036261506258 1.5974373596628326 0.110168250269552 1.0 0.274463314884835 19 Q8N6G5,Q8N4A0,Q10472,Q16739 4 +Solute anion antiporter activity 0.7640289034457228 1.5957857714595618 0.110536631085542 1.0 0.2747901864003737 6 P05141,P12236,P12235,P41440 4 +Cation cation antiporter activity 0.8071950534007891 1.5931839730742885 0.111118925536922 1.0 0.2757539710784913 3 O95202,Q92581 2 +Neutral amino acid transmembrane transporter activity 0.7843082114735472 1.5922542421127206 0.1113275898661352 1.0 0.2757888021683804 5 P08195,Q96NB2,Q9H9B4,Q96QD8 4 +Solute cation antiporter activity 0.8074219848186603 1.578182928525766 0.1145235909749224 1.0 0.2802762148729968 4 O95202,P51790,Q92581 3 +Voltage gated chloride channel activity 0.8024170882518293 1.5737201725374166 0.1155521560948151 1.0 0.2813357477428747 3 Q4KMQ2,P51790 2 +Signaling receptor regulator activity 0.5034061010114339 1.568746821755386 0.116706943918124 1.0 0.2816720260766547 23 P22466,Q92520,P30533,O00255,Q9UMX5,P43490,P05067,P49354 8 +Cardiolipin binding 0.801011804384488 1.5679921777279595 0.1168829578920769 1.0 0.2816720260766547 3 Q9UJZ1,O60313 2 +Solute sodium symporter activity 0.803431036482775 1.5621311554032733 0.1182570947005907 1.0 0.2835190453350077 4 Q9Y6M7,Q96QD8 2 +Tap binding 0.7758717660292345 1.5574779748532457 0.1193570458558355 1.0 0.2847288450803348 5 P01889,P10321,Q03519,Q03518 4 +Metalloendopeptidase activity 0.5699010980069388 1.5480235687979274 0.1216166221267747 1.0 0.289145559653758 14 Q10713,Q92905,P42892,P22695,O75844,P14735,Q96TA2 7 +Iron ion binding 0.4890633169470635 1.5445369645854887 0.1224583035259163 1.0 0.2901729366157583 25 Q6UW02,Q15800,Q16850 3 +Amino acid cation symporter activity 0.7920631530072662 1.5314835960365136 0.125649917565001 1.0 0.2957573641023362 3 Q96QD8 1 +Nadp binding 0.5185109126797134 1.512141207372732 0.130497943791281 1.0 0.3031403054954839 19 Q13423,Q14739,P00374,O76062,Q9UBM7,P16435 6 +Oligosaccharyl transferase activity 0.788023615406231 1.5000433051274205 0.1336031853500778 1.0 0.3078304286846509 4 Q8TCJ2,P04843,P46977 3 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.788023615406231 1.5000433051274205 0.1336031853500778 1.0 0.3078304286846509 4 Q8TCJ2,P04843,P46977 3 +L serine transmembrane transporter activity 0.7838673412029263 1.4979999127578152 0.1341332731241347 1.0 0.3085500779495111 3 Q9H9B4,Q96QD8 2 +C4 dicarboxylate transmembrane transporter activity 0.739849782871187 1.4939504556554628 0.1351885692764529 1.0 0.3104735861665054 6 Q9UJS0,Q9UBX3,O75746,Q02978 4 +Cytokine activity 0.6914084294655276 1.4875844916487782 0.1368605058108212 1.0 0.3123120629291763 7 P43490,O00255,P09429,Q92520 4 +Mitochondrial ribosome binding 0.7813104923406079 1.487545836904467 0.136870706477783 1.0 0.3123120629291763 3 Q15070 1 +Serine transmembrane transporter activity 0.7840877143660255 1.4841551797520902 0.1377677571858493 1.0 0.313853556161332 4 Q96NB2,Q9H9B4,Q96QD8 3 +Potassium ion transmembrane transporter activity 0.6893907985573716 1.4785079774891912 0.1392718634227656 1.0 0.3155679872397532 7 P05023,P55011,Q9BXP2,Q96ER9,Q92581 5 +Long chain acyl coa dehydrogenase activity 0.7819092068839415 1.475356814261986 0.140116639358395 1.0 0.3161549012274613 4 Q9NZ01 1 +Signal recognition particle binding 0.7345703870335913 1.471634302075888 0.1411196574063653 1.0 0.3169042068856096 6 Q9BUN8 1 +Structural constituent of eye lens 0.7765598650927514 1.4681128321927377 0.1420735764969916 1.0 0.3171787354674125 3 P08670,Q99797 2 +Intramembrane lipid transporter activity 0.7799887899889062 1.4675983438820723 0.1422133581357252 1.0 0.3171787354674125 4 P08183 1 +Calcium ion transmembrane transporter activity 0.5473219509386833 1.4645631226958675 0.143040149439334 1.0 0.318191352834437 15 Q9HC07,Q9UM00,P16615 3 +G protein alpha subunit binding 0.7770057929654782 1.45554267096418 0.1455190860136799 1.0 0.3217017051700803 4 Q02818 1 +Voltage gated channel activity 0.5901431295253822 1.4547557610640782 0.1457368894117916 1.0 0.3217017051700803 11 Q4KMQ2,P0CG08,Q9Y277,P21796,P45880 5 +Peptidase activity 0.3568077993536974 1.4383358526103454 0.1503387838961256 1.0 0.3287500876247068 125 P10619,Q10713,Q15005,P09960,Q8TCT8,P42892,O75844,Q7Z2K6,Q969V3,Q9H3G5,P55786,O14773,O43292,Q92643,Q16740,Q9HB40,P42785,P67812 18 +Protein lipid complex binding 0.7246764568657241 1.4297440990897428 0.1527904784028664 1.0 0.3330283579743169 6 Q9BQE5 1 +Atpase binding 0.4593312740584528 1.4209844251093773 0.1553212873492742 1.0 0.3365294559234274 28 Q92542,Q5JTV8,P40855,Q93050,P35241,O76024,Q16740,Q9BUN8,Q8NFQ8 9 +Lipid transfer activity 0.6727829112717099 1.4036221257043064 0.16043140293473 1.0 0.3437645169531382 7 Q14849 1 +Mhc class ib protein binding 0.7578948706474252 1.3916666197218706 0.1640233749266051 1.0 0.3489526453538853 3 Q03519 1 +Class i dna apurinic or apyrimidinic site endonuclease activity 0.6670413037370009 1.3846661569698475 0.1661545720117785 1.0 0.3514045202099853 2 P78549 1 +Nitric oxide synthase binding 0.6653554369204806 1.3767694617118449 0.1685835352563944 1.0 0.3538429070790236 2 P50570 1 +Transcription elongation regulator activity 0.6647934813149732 1.374137186397932 0.1693990967873575 1.0 0.3540391152620732 2 O14776 1 +Polypeptide n acetylgalactosaminyltransferase activity 0.7556242023731381 1.3689992577643555 0.1709995069233092 1.0 0.3568575866131505 4 Q10472 1 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.7542876360034524 1.3635833734966196 0.172698727894637 1.0 0.3588191604597222 4 Q9UHG3 1 +Phosphatidylglycerol binding 0.7542873207759252 1.3635820961034777 0.1726991301577491 1.0 0.3588191604597222 4 O60443,Q9UJZ1,O60313 3 +Hyaluronic acid binding 0.6583309918516347 1.3438659743818058 0.1789917306162887 1.0 0.3713488759638083 2 Q07021 1 +Peroxisome targeting sequence binding 0.7436762225969679 1.3333681908947712 0.1824110057349321 1.0 0.3769987313788761 3 P50542,P40855 2 +S acyltransferase activity 0.6567560766935949 1.331103638224022 0.1831549120222213 1.0 0.3777736686106079 7 Q8IUH4 1 +Atpase coupled cation transmembrane transporter activity 0.5166481683856106 1.3292305946785938 0.183771904253172 1.0 0.3783847227742615 16 P05023,P16615,P36543,P35670,P20020,P06576,Q9HD20 7 +Volume sensitive anion channel activity 0.7456530686878159 1.3285840649350642 0.1839852321746409 1.0 0.3783847227742615 4 Q9C0H2 1 +Ammonium transmembrane transporter activity 0.651587524585554 1.3122834293739265 0.1894245210853351 1.0 0.3855419548981203 2 P55011 1 +Structural constituent of ribosome 0.3485837215456073 1.3116388442187283 0.1896420201580733 1.0 0.3855419548981203 114 Q02878,P39023,P27635,P61927,Q96A35,Q9NWU5,P84098,P18124,Q9BYD1,P62266,P62910,P46779,P50914,P62424,P82933,Q9BYD2,P82663,Q9Y2Q9,P46776,P49406,P47914,P40429,O95182,P61513,Q13084,P46778,P62917,Q9Y3B7,Q5T653,Q9P015,P82650,P82930,Q07020,P61313,P83881,Q9Y2R9,P36578,Q9HD33,Q7Z7H8,Q9Y3U8,P82912,Q02543,P18077,Q92665,P62241,Q9Y3D9,P62847,P62854 48 +Lysophospholipase activity 0.7397515986692981 1.3046550438113145 0.1920103360745075 1.0 0.3892398372211405 4 Q8N2K0,Q8NCC3 2 +Dipeptidyl peptidase activity 0.7381862572162617 1.29830733254395 0.1941817477294165 1.0 0.3911324945817071 4 P42785 1 +Ionotropic glutamate receptor binding 0.7092841111495627 1.2810658841901603 0.2001705255926571 1.0 0.3978143545088291 5 O75955,P27824 2 +Peptide binding 0.3703122524740332 1.2713887520666698 0.2035903821438534 1.0 0.4030245538827608 81 P30533,P01889,P10321,Q03518,P55899,Q8WTV0,P24390,P55786,Q9Y3C6,Q15392,P40855,Q9H7Z7,O00264,O14773,P42892,Q99735,P14735,Q03519,Q9Y287 19 +Protein disulfide isomerase activity 0.5762291504383363 1.2707629991432958 0.2038129756618087 1.0 0.4030245538827608 9 Q92643 1 +Atp dependent peptidase activity 0.7033907195894957 1.2565067053235288 0.2089323163650203 1.0 0.4083546100541155 5 Q16740 1 +Chloride channel inhibitor activity 0.7272543649727605 1.2539758868063977 0.2098507700688323 1.0 0.4095847674759441 4 Q9UEU0,O15400 2 +Flavin adenine dinucleotide binding 0.4278843884333077 1.2440234138230428 0.2134909457939937 1.0 0.4161164651858173 30 P49748,O15254,Q16134,Q14534,O00116,Q15392,P16435 7 +Thiolester hydrolase activity 0.5099551010259706 1.2420659119026074 0.2142122443419312 1.0 0.4169488327369732 15 P28288,Q9UMR5,P50897,Q9NUJ1 4 +Cytoskeleton nuclear membrane anchor activity 0.7184208604884816 1.2181630934462562 0.2231620014901281 1.0 0.4253748042415473 4 Q9UH99 1 +Acid phosphatase activity 0.7145450138836578 1.2024556286053028 0.2291870475142046 1.0 0.4320715731988016 4 Q9NPH0 1 +Peptidyl proline 4 dioxygenase activity 0.7114731025424987 1.201377694591314 0.2296047245015509 1.0 0.4320715731988016 3 P07237 1 +Procollagen proline 4 dioxygenase activity 0.7114731025424987 1.201377694591314 0.2296047245015509 1.0 0.4320715731988016 3 P07237 1 +L aspartate transmembrane transporter activity 0.7107112735451148 1.186923915995299 0.2352576328091753 1.0 0.4381906994680642 4 O75746,Q15758,Q9UJS0 3 +Acidic amino acid transmembrane transporter activity 0.7107112735451148 1.186923915995299 0.2352576328091753 1.0 0.4381906994680642 4 O75746,Q15758,Q9UJS0 3 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.437344015479824 1.1867025784312648 0.2353449576337267 1.0 0.4381906994680642 26 O43676,Q9Y6M9,Q9P0J0,P03886,O95168,P51970 6 +Chemoattractant activity 0.6859480897130392 1.1838216953101872 0.2364836522207907 1.0 0.4385354759588653 5 O00255,P09429 2 +Peptidyl proline dioxygenase activity 0.677062074727831 1.1468183358119282 0.2514567094800497 1.0 0.4562281143831376 5 P07237,Q8N543,P13674 3 +Aspartic type peptidase activity 0.700013599506042 1.1436204781090258 0.2527810652804394 1.0 0.4580444622792617 4 Q8TCT8,Q92542 2 +Steroid dehydrogenase activity 0.5739725094028418 1.1415932368163642 0.2536231365576968 1.0 0.4589833773975178 8 Q3SXM5 1 +Acyl coa binding 0.528970383835323 1.1281769795582957 0.2592451839508591 1.0 0.4636398256060217 11 P49748,P40939,Q5T8D3 3 +Fatty acid derivative binding 0.528970383835323 1.1281769795582957 0.2592451839508591 1.0 0.4636398256060217 11 P49748,P40939,Q5T8D3 3 +Nadplus binding 0.6112685863446206 1.124548822431932 0.260780270775979 1.0 0.4636457260847706 7 P40939,Q8IXJ6 2 +Glutamate receptor binding 0.6104691614319855 1.1209170652152 0.262323166161766 1.0 0.4652214348576 7 O75955,P27824 2 +Long chain fatty acid transporter activity 0.6913804703472082 1.1087265607324084 0.2675481601181642 1.0 0.4721242128112561 4 O14678 1 +Structural constituent of postsynapse 0.6666639171468847 1.1035656662266364 0.2697815916395791 1.0 0.4737057191490504 5 P12814,P07196,Q12959 3 +Hormone binding 0.5643184118335932 1.0946698779672466 0.273661289697015 1.0 0.4775591717988549 8 P05023,P42892,P30536 3 +Glucosidase activity 0.662316457888511 1.0855027843289409 0.2776990311752016 1.0 0.4804634031443965 5 P04062,P10253 2 +Phosphoric diester hydrolase activity 0.5153233512669727 1.0549143562627523 0.2914644957748384 1.0 0.4981968522472209 11 P09601,Q8N2A8 2 +Histone methyltransferase binding 0.6346295003014268 1.0466220653860672 0.2952739209395738 1.0 0.5024653945590616 6 P83916,O95785 2 +Mannosyltransferase activity 0.6345752821985946 1.0463918570063282 0.2953801507887779 1.0 0.5024653945590616 6 Q9BT22,Q6ZXV5 2 +3 hydroxyacyl coa dehydrogenase activity 0.6272540339990309 1.0153317924287275 0.3099476943694261 1.0 0.5206519585576826 6 P40939 1 +Ubiquitin specific protease binding 0.5226932253082263 0.9989794488746484 0.3178046468717526 1.0 0.531675542641409 9 Q6NTF9,Q9BUN8,P46379 3 +Phospholipid transporter activity 0.5826402778854198 0.9947157520930622 0.3198745310359081 1.0 0.5326230440398141 7 P08183 1 +Nadph binding 0.6177076987975191 0.9749219908646553 0.3295989568846982 1.0 0.5430717696576945 6 Q14739,P00374 2 +Procollagen proline dioxygenase activity 0.6559023549180782 0.9661578464777733 0.3339652024055708 1.0 0.545194345401721 4 P07237,P13674 2 +Nucleoside monophosphate kinase activity 0.5073502509474346 0.9645092695611568 0.3347906633249582 1.0 0.5459129688509388 10 Q9UIJ7 1 +Potassium chloride symporter activity 0.6517706576728548 0.9588102216704714 0.3376543588620602 1.0 0.5464746580369262 3 Q9BXP2,P55011 2 +Anion cation symporter activity 0.6517706576728548 0.9588102216704714 0.3376543588620602 1.0 0.5464746580369262 3 Q9BXP2,P55011 2 +Cation chloride symporter activity 0.6517706576728548 0.9588102216704714 0.3376543588620602 1.0 0.5464746580369262 3 Q9BXP2,P55011 2 +Metalloaminopeptidase activity 0.473980209143991 0.9321118370770816 0.3512787312752472 1.0 0.5613263653020498 13 P09960,P55786 2 +Molecular carrier activity 0.364483692608068 0.9053297347283126 0.3652907282086275 1.0 0.57385472491311 35 Q9P0I2,Q8N766,O75880,Q9NPA0,Q8N4V1,Q15070,O15504,Q5J8M3,P40855 9 +O methyltransferase activity 0.5017140747113613 0.8928605853904118 0.371931836714223 1.0 0.5823861918374431 9 O60725 1 +P type calcium transporter activity 0.630659213821965 0.8660227149740534 0.3864777052560781 1.0 0.5975814866962957 4 P16615 1 +Nadp retinol dehydrogenase activity 0.6031946276186751 0.8423668573981088 0.3995826384504082 1.0 0.6105882151478713 5 Q8TC12,Q9Y394,Q8NBN7 3 +Mannose binding 0.5817400990240673 0.8240634803603051 0.4099034892752207 1.0 0.6185657553812436 6 P35613,O75503 2 +Chloride channel regulator activity 0.5927226744271192 0.8000829056998214 0.4236627645979074 1.0 0.6309807110786663 5 Q9UEU0,O15400 2 +Nitric oxide synthase regulator activity 0.6063908980506743 0.7793118856449448 0.4357960148864537 1.0 0.6419157516570737 3 P07900 1 +Amyloid beta binding 0.4524239243714225 0.762645211479573 0.4456750135668865 1.0 0.6520768979562345 12 Q8WTV0,O00264 2 +Scaffold protein binding 0.3945023862026861 0.7277315821459212 0.4667779134435883 1.0 0.6708157234782602 21 P12956,Q9NZJ7,P08670,P07602 4 +Oxidoreductase activity acting on the ch nh group of donors 0.4684309640623215 0.726547005348519 0.4675035024156644 1.0 0.6711777739847988 9 P00374 1 +Oxidoreductase activity acting on ch oh group of donors 0.3435869953373112 0.7069517701329906 0.4795964502680223 1.0 0.6800956661021006 58 Q96LJ7,Q8N0U8,P51648,Q06136,P40939,Q8N4Q0 6 +Metal dependent deubiquitinase activity 0.5172104792198393 0.7032765950630508 0.4818833935824465 1.0 0.6806827225906459 7 P51665,Q92905,O15372,O00487 4 +Protease binding 0.3620609916695628 0.7014868354948723 0.4829992473627378 1.0 0.6806827225906459 30 Q6NTF9,Q9NZJ7,P41440,O75955,P07602,P46379,Q9BUN8 7 +Aminopeptidase activity 0.4104650296122306 0.676502132750385 0.4987218924048928 1.0 0.6941097154860035 16 P53582,P09960,P55786 3 +N acyltransferase activity 0.383543008546893 0.6758549510151038 0.499132741947808 1.0 0.6941097154860035 22 Q8N5B7,Q969G3,O75448,P27544,Q96G23,Q9UPT9,Q96QD8 7 +Chloride ion binding 0.5099747119977517 0.6695328452070491 0.5031556359531419 1.0 0.6976238122755402 2 Q96DE0 1 +Fatty acid transmembrane transporter activity 0.5068839561674627 0.6565087161051811 0.5114968613074222 1.0 0.7043644824806776 2 O14975 1 +Lrr domain binding 0.5063220005619431 0.6541486101778745 0.5130160663337613 1.0 0.7050860969883024 2 Q9NY61 1 +Leucine zipper domain binding 0.5063220005619431 0.6541486101778745 0.5130160663337613 1.0 0.7050860969883024 2 Q9NY61 1 +Thiol oxidase activity 0.5713795231034051 0.6462084577919361 0.5181443628203861 1.0 0.7093821856197944 3 P07237 1 +Transferase activity transferring alkyl or aryl other than methyl groups 0.3708433208916439 0.640009607415311 0.5221663533885799 1.0 0.7121364030333183 24 P37268,P49354 2 +Phosphotransferase activity phosphate group as acceptor 0.4210277047127241 0.635181395106889 0.52531011590418 1.0 0.7144775793425509 13 Q13232,Q9UIJ7 2 +Endopeptidase activity 0.3307971178605355 0.6300040415667688 0.5286919399751837 1.0 0.717582834238348 68 Q92542,Q6NTF9,P14735,Q10713,Q92905,Q8TCT8,P42892,P22695,O75844,Q8TCT9,Q92643,O43292,Q16740,O14773,P49721,P28072,Q96TA2,P67812 18 +Supercoiled dna binding 0.5444319460067416 0.6104581731080568 0.5415583426667245 1.0 0.7300401373161357 5 P09429,P23396,P26583,P11387 4 +Molybdopterin cofactor binding 0.4911491992132568 0.5914100367867269 0.554245717044179 1.0 0.7423120803890375 2 Q5VT66 1 +Solute proton symporter activity 0.4894633323967413 0.5845634183171986 0.5588413111887762 1.0 0.7463173423538004 2 Q9H936 1 +Transcription regulator inhibitor activity 0.5534007869589723 0.5804455513888325 0.5616141946418747 1.0 0.74786279538036 3 Q96ST3,Q9NX58 2 +Phospholipase a2 inhibitor activity 0.4858106209609402 0.5698203009649203 0.5687995849579368 1.0 0.7543081993149283 2 P04083 1 +Cyclin dependent protein serine threonine kinase inhibitor activity 0.4844057319471637 0.5641838344645239 0.5726290282533157 1.0 0.7576240271101292 2 O94992 1 +Chaperone binding 0.3293938462749695 0.5527264628280603 0.5804507299637252 1.0 0.761655286653245 44 P05023,Q14108,O43808,P01889,Q96KC8 5 +Hexosaminidase activity 0.5290406758084076 0.5525058846828433 0.5806018037488045 1.0 0.761655286653245 5 P54802 1 +Galactosyltransferase activity 0.543436693461322 0.537435069031132 0.5909671247937249 1.0 0.7647492382033865 4 Q96L58,O43505 2 +Dynein light chain binding 0.4765383534700783 0.5329827442421913 0.5940455253289603 1.0 0.7673313668105166 2 Q86VS8 1 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides 0.4016802179019673 0.530203519503585 0.5959708311156353 1.0 0.7688778304426681 13 Q13510 1 +Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor 0.5215460456518176 0.5248411029690069 0.5996936554418273 1.0 0.7718128154051492 5 P12694 1 +Carbohydrate binding 0.325933983553737 0.513949860529438 0.6072870461508928 1.0 0.7774768935007379 49 P35613,Q8N4A0,P27824,Q9NPA0,P49257,O75503,P52789,Q10472,P10253,O14735,Q8N543,Q9BWS9 12 +Small ribosomal subunit rrna binding 0.518194223276142 0.5125963880421223 0.6082336803288697 1.0 0.7778584160884552 5 Q14011,P62277,P82912 3 +Intramolecular transferase activity 0.4037620173216248 0.5046216175131807 0.6138246235051379 1.0 0.7821472160808789 12 P48449 1 +Acetyltransferase activity 0.337409639789333 0.5005776185947675 0.6166684172424162 1.0 0.7843977982338453 30 Q8NF37,Q969G3,O75448,Q9BWD1,P40939,Q96QD8 6 +Pdz domain binding 0.3720019061566065 0.4746175269338507 0.6350596113613813 1.0 0.8027470734157692 17 P63218,Q9UBI6,P51790,Q9BY67,Q9UQB8,P20020 6 +Cysteine type endopeptidase regulator activity involved in apoptotic process 0.4620042434148095 0.4717515095036562 0.6371041660276939 1.0 0.8038972424409994 7 P51812 1 +Gtp dependent protein binding 0.4080979992985266 0.4396121598490305 0.6602180321782625 1.0 0.823529006687146 9 P53365,Q9BZG1,Q86YV9 3 +Syntaxin binding 0.3461568298900471 0.4377252873976451 0.661585436208389 1.0 0.8245088505780891 23 Q9P253,Q9BVK6,O60499,O15400,Q9UNK0,P49755,Q5SQN1 7 +Atpase activator activity 0.3761973548843165 0.4316372802969464 0.6660050586520956 1.0 0.8292874939455355 14 Q5JTV8,O60884,P05026,Q96KC8,Q8NFQ8,Q92759 6 +Acetyl coa c acetyltransferase activity 0.4943276332353258 0.4279468556610587 0.6686898126497276 1.0 0.8301917359977993 5 P40939 1 +Hydrolase activity hydrolyzing o glycosyl compounds 0.3475200423428799 0.4269047855349257 0.6694486797881787 1.0 0.8301917359977993 22 P04062,Q13724,P04066,Q9NUJ1,P10253,P16278,P17900,P54802,P08236 9 +C acyltransferase activity 0.3995340857171336 0.4247417206774564 0.6710249664986723 1.0 0.8301917359977993 10 P40939,Q9BWD1 2 +Acetyl coa c acyltransferase activity 0.4500082397874394 0.4244424272451927 0.6712431843541029 1.0 0.8301917359977993 7 P40939 1 +C acetyltransferase activity 0.4782759382599115 0.4187664510506797 0.6753868257160167 1.0 0.8336438432400659 6 P40939 1 +Cell cell adhesion mediator activity 0.3572257301570761 0.4136982218940278 0.6790951294642751 1.0 0.835764815914421 18 P35613,Q08722,Q9NYL9,Q9Y639,Q9UQB8 5 +Rna polymerase ii c terminal domain phosphoserine binding 0.4433829727451353 0.4091719556746755 0.6824134735448024 1.0 0.835764815914421 2 Q8WVC0 1 +Transmembrane transporter binding 0.3103418938415678 0.4032090261573701 0.6867944601128937 1.0 0.8382323427906722 37 P16615,Q12959,P30536,P21796,Q9Y639,Q96SB3,P12814 7 +Pentosyltransferase activity 0.3548230265638551 0.3992152159251249 0.6897346325371989 1.0 0.8389304500473913 18 P43490,Q8IXJ6 2 +Cyclin dependent protein serine threonine kinase activator activity 0.4335487496487673 0.3751792717495144 0.7075271449102332 1.0 0.8532476292236599 2 O75909 1 +Snare binding 0.3068687185386196 0.3723207073965026 0.7096540828350679 1.0 0.8543583987912415 37 Q9P253,Q9UEU0,Q9BVK6,O60499,O15400,P49755,Q5SQN1,Q12846,Q86Y82 9 +Monocarboxylic acid transmembrane transporter activity 0.4754160799209741 0.3644727910172105 0.7155049882096536 1.0 0.8584848165055708 5 O95563 1 +Cell adhesion mediator activity 0.340175366055628 0.3489857882071873 0.7270999789978232 1.0 0.8657988825545507 20 P35613,Q08722,Q9NYL9,Q9Y639,Q9UQB8 5 +Neurexin family protein binding 0.4161281258780425 0.3184822335742215 0.7501191691754978 1.0 0.8784453410922978 2 O00560 1 +2 iron 2 sulfur cluster binding 0.3755471739141311 0.3172522299338537 0.7510522214336741 1.0 0.8788117240062067 10 P22830 1 +Collagen binding 0.3790473080643474 0.3135925500097785 0.7538305185555374 1.0 0.8806082809506979 9 Q53GQ0 1 +Cdp alcohol phosphatidyltransferase activity 0.4698020121511664 0.3093650679780325 0.7570438396211119 1.0 0.8836335426220061 3 O14735 1 +Hydro lyase activity 0.3391801241950084 0.3069911785225222 0.7588500867574757 1.0 0.8848010741918909 18 Q9P035,P40939 2 +Carboxylic ester hydrolase activity 0.3045913655490717 0.3055893034046835 0.7599173657667828 1.0 0.8848010741918909 33 Q8NCC3 1 +G protein coupled serotonin receptor binding 0.4631815626756686 0.2910360160014478 0.7710237743636583 1.0 0.8940944578206353 3 P63096,P09471 2 +Pre mrna intronic binding 0.4497795329107973 0.2844555603733153 0.7760612856135833 1.0 0.8967537046598333 5 P22626 1 +Long chain fatty acyl coa binding 0.4032031469513874 0.2795538079507741 0.7798198504170444 1.0 0.8984492659857612 2 P22307 1 +Structural constituent of muscle 0.4310385277839776 0.2617208339385809 0.7935366770938206 1.0 0.9102442522525918 6 P09493 1 +Aminophospholipid flippase activity 0.3967406574880535 0.2611530007450354 0.7939745206663398 1.0 0.9102442522525918 2 Q9NV96 1 +Endopeptidase activator activity 0.4367266591676068 0.2467285612635657 0.8051183010723764 1.0 0.9185608958289512 5 Q06323,Q9UL46,P61289,O00487 4 +Heparin binding 0.3367049519231425 0.2419984744655424 0.8087813453049257 1.0 0.9219977202711824 15 P05067,Q53GQ0,P47914,P10586 4 +Ephrin receptor activity 0.3885923012082075 0.2390002494515617 0.8111053893114049 1.0 0.923903807599888 2 Q15375 1 +Proline rich region binding 0.4330166731607593 0.2364067673206936 0.813117045442842 1.0 0.9250781714108398 5 P46934 1 +Structural constituent of nuclear pore 0.3197990130226838 0.2347248814399528 0.8144222745926895 1.0 0.925450170888405 21 Q9BTX1,Q8N1F7,Q92621,P37198,A8CG34,Q7Z3B4,P12270 7 +Rna polymerase ii c terminal domain binding 0.4436322743885263 0.2297632380950484 0.8182757522596056 1.0 0.9283400648133396 4 Q00839,Q8WVC0,Q9H7N4 3 +Adrenergic receptor binding 0.4236667409625235 0.2112152910297646 0.832719279387532 1.0 0.9390176764656012 5 P46934 1 +Very long chain fatty acid coa ligase activity 0.4357604723081196 0.2102947747647092 0.833437613243901 1.0 0.9390176764656012 4 O14975,Q4G176,Q6P1M0 3 +Phosphatidylinositol phosphate phosphatase activity 0.3623508115852621 0.2002784061622891 0.8412628497949954 1.0 0.9437106162725132 8 Q10713 1 +Opsonin binding 0.4261578827231497 0.1990896023404048 0.84219265455526 1.0 0.9437106162725132 3 Q07021 1 +Complement binding 0.4261578827231497 0.1990896023404048 0.84219265455526 1.0 0.9437106162725132 3 Q07021 1 +Tropomyosin binding 0.4259930880992972 0.1987224810664778 0.8424798373921871 1.0 0.9437106162725132 3 Q9NYL9 1 +Carbon sulfur lyase activity 0.3833941527903862 0.1918805948344791 0.847835738074745 1.0 0.9482109241135862 7 O14880,Q99735,P53701 3 +Hydrolase activity acting on glycosyl bonds 0.2951579545174482 0.1904991926511048 0.8489179757738521 1.0 0.9482869401569516 31 O75503,P04062,P17900,P16278,P54802 5 +N6 methyladenosine containing rna binding 0.4147039161585464 0.1882063779798363 0.8507148729284246 1.0 0.949183444834313 5 P22626,Q9BYJ9 2 +Cobalamin binding 0.423671633398934 0.1820317477222177 0.8555578110327902 1.0 0.9538358916077604 4 Q9NPF0,P22033,Q99707 3 +Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor 0.3090940640615957 0.1713196665469765 0.8639724173996952 1.0 0.9572320836496206 21 P51648 1 +Structural molecule activity conferring elasticity 0.3599325653273441 0.1707621027638451 0.8644108289354793 1.0 0.9572320836496206 2 P11047 1 +Syntaxin 1 binding 0.4111860595840449 0.1673295300571975 0.8671107700590626 1.0 0.9589252053046946 3 O00186,O75150 2 +Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor 0.3966766591867381 0.1650301789222355 0.8689202283777191 1.0 0.9589252053046946 6 P51659,Q53GQ0,Q15738 3 +Molecular function activator activity 0.3185743442501173 0.1556670906825531 0.8762954387165434 1.0 0.9648101294959922 15 Q5JTV8,Q96KC8,Q8NFQ8 3 +G protein beta subunit binding 0.4047970957560657 0.1547683588147544 0.8770039366039859 1.0 0.964840510999882 3 Q9UBI6 1 +Oligopeptide binding 0.3986344863557784 0.1498658228681087 0.8808704765349291 1.0 0.9669017179004682 5 Q9H7Z7 1 +Tpr domain binding 0.4056789429294342 0.1437603430445736 0.8856897191726596 1.0 0.9690926085352576 4 O76094,P07900,P08238 3 +Protein homodimerization activity 0.2667710743576189 0.1408531862251968 0.8879859253209412 1.0 0.9693960371184696 190 P09601,Q8N2A8,Q14108,Q9NZJ7,P07602,Q9UKK9,Q8TCT8,P42892,O00264,O95772,Q07820,Q8TBA6,P51648,Q15070,P27105,P22830,Q9UKU0,Q14849 18 +Single stranded dna endodeoxyribonuclease activity 0.3948847667228863 0.1364666396544503 0.8914523954927565 1.0 0.9715869228123702 3 Q92889,P49959 2 +Long chain fatty acid binding 0.341107052542855 0.1343609579574793 0.893117152679139 1.0 0.9715869228123702 2 Q00169 1 +Calcium channel inhibitor activity 0.3397021635290864 0.1319124069373252 0.8950535750718722 1.0 0.9715869228123702 2 Q9NRX4 1 +Epidermal growth factor receptor binding 0.3894825646794264 0.1297568170945586 0.8967588289542257 1.0 0.9715869228123702 5 P62993,Q92600,P18085,O60749 4 +Mdm2 mdm4 family protein binding 0.3822784810126597 0.1296966819232942 0.8968064078365998 1.0 0.9715869228123702 6 P62841,P61927,P61289,P04637,Q96JB5 5 +Dioxygenase activity 0.3002058394026691 0.128547252742066 0.8977159060976556 1.0 0.9715869228123702 22 O00625,Q8IUF8,Q9BV57,Q8N543,P16435 5 +Gamma catenin binding 0.3904976103457968 0.1150951735837481 0.9083696854046512 1.0 0.981066954434749 4 P19022,P35221,Q14574 3 +Phosphatidylcholine transfer activity 0.3253722955886549 0.1090235395710957 0.913183819742328 1.0 0.982456107574278 2 Q00169 1 +Phosphatidylinositol transfer activity 0.3253722955886549 0.1090235395710957 0.913183819742328 1.0 0.982456107574278 2 Q00169 1 +Phospholipid transfer activity 0.3253722955886549 0.1090235395710957 0.913183819742328 1.0 0.982456107574278 2 Q00169 1 +Map kinase activity 0.3707138842046152 0.0978815143612219 0.9220263788940636 1.0 0.989032080918159 3 Q16539,P27361 2 +Trna cytosine methyltransferase activity 0.3146951390840127 0.0943771817719406 0.9248095411969026 1.0 0.9912671103449402 2 Q9H649 1 +Peptidase activator activity 0.3111794689470767 0.0908912497979319 0.927579003063294 1.0 0.993163996916152 12 Q9BXK5 1 +Poly g binding 0.3465541490857947 0.05639763689823 0.9550250394430402 1.0 1.0 6 Q86TB9,Q96EP5,O14979,Q06787,Q00839 5 +L ascorbic acid binding 0.3129408078989551 0.0554678683639308 0.9557657278566124 1.0 1.0 8 Q8N543,P13674,O60568,Q32P28 4 +Isopeptidase activity 0.3035764573359686 0.053504583732367 0.9573298785923794 1.0 1.0 10 Q9H4L4,Q7L5N1,Q6P2Q9,O00487,Q9P0U3,O15372,Q92905,P51665,O00303 9 +Oxidoreductase activity acting on the aldehyde or oxo group of donors 0.2852862102908955 0.0527360594628857 0.9579422076913148 1.0 1.0 23 P51648 1 +Carbon oxygen lyase activity 0.2845053917702825 0.0484446407487091 0.9613618828751864 1.0 1.0 23 Q9P035,P40939,Q6Y1H2 3 +Phosphatidylinositol phosphate kinase activity 0.3181562675660538 0.0418521831196555 0.9666165353125488 1.0 1.0 3 Q8TBX8,P48426 2 +Growth factor receptor binding 0.2905860759835195 0.0405182770088047 0.9676799360601328 1.0 1.0 16 Q92542,P05067,Q9Y639,Q9NZ08 4 +Phosphotransferase activity for other substituted phosphate groups 0.3225838139038123 0.0403521749556013 0.9678123580240356 1.0 1.0 7 Q5H8A4 1 +5s rrna binding 0.3364084190545798 0.0393971262967657 0.9685737710154764 1.0 1.0 6 P39023 1 +Ribosome binding 0.2706265231079953 0.0311712812140728 0.9751329430516044 1.0 1.0 42 Q9UM00,Q969V3,P46379,Q15070,Q96A33 5 +H4 histone acetyltransferase activity 0.3236922445442481 0.027869234804829 0.9777664459773424 1.0 1.0 4 Q9UPT9 1 +Dynein heavy chain binding 0.323587292662356 0.0277787061620552 0.9778386494292935 1.0 1.0 4 Q13409,Q9Y6G9,O43237 3 +Calmodulin dependent protein kinase activity 0.2759977515458195 0.0194429563768474 0.98448774264274 1.0 1.0 3 Q13555,P46020 2 +Acetyl coa hydrolase activity 0.2639644493569114 0.015708340176714 0.9874670733199652 1.0 1.0 3 Q9Y305 1 +N acetyltransferase activity 0.2823132008081301 0.0107150020409446 0.991450828893069 1.0 1.0 17 Q969G3,Q9UPT9,Q96QD8,O75448 4 +Dopamine receptor binding 0.3052898142937641 0.0097630704662024 0.9922103205580366 1.0 1.0 7 Q15334,Q96QK1,Q9Y5X3,Q96SB3,Q14344,P50570 6 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..117f6cba279ab7323c9ac2c350c677a4de7eb569 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5alpha androstane 3beta 17beta diol dehydrogenase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin activated receptor activity", "Activin binding", "Activin receptor activity type i", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Aryl sulfotransferase activity", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Bioactive lipid receptor activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Choline transmembrane transporter activity", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromatin insulator sequence binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co receptor binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Copper ion transmembrane transporter activity", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Corticotropin releasing hormone receptor binding", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction hemi channel activity", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Ige binding", "Igg binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inhibin binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Narrow pore channel activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neuregulin binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neuropeptide hormone activity", "Neuropeptide receptor activity", "Neuropeptide receptor binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opioid receptor binding", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion antiporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Potassium proton antiporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein cysteine s stearoyltransferase activity", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoic acid responsive element binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine 1 phosphate receptor activity", "Sphingosine n acyltransferase activity", "Stat family protein binding", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein serine threonine kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor binding", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific endopeptidase activity", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Wnt protein binding", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding"], "available_proteins": ["AACS", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOL2", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID4A", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPIF1", "ATRIP", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRIP1", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "C2CD5", "CAB39", "CACTIN", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC51", "CCDC59", "CCDC6", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDR2L", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP250", "CEP290", "CEP350", "CEP44", "CEP55", "CEP97", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFL1", "CFL2", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHML", "CHMP1A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLN5", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "CORO1C", "CORO7", "COTL1", "COX11", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND4C", "DENR", "DEPDC1B", "DERL1", "DERL2", "DFFA", "DFFB", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAHD2A", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAU", "FBL", "FBXO21", "FBXO22", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1B", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FOXK1", "FOXRED1", "FPGS", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GAL", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GID8", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOPC", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPRASP2", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H1", "GTF2H4", "GTF2I", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "GXYLT1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2B", "ITPA", "ITPRIP", "ITSN2", "IVD", "JMJD6", "JUP", "KARS", "KAT7", "KCMF1", "KCTD10", "KCTD12", "KCTD15", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIN", "KLC1", "KLC2", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIG4", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGT1", "MAIP1", "MAK16", "MALT1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP7D3", "MAP9", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MVB12A", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NEO1", "NES", "NF1", "NFRKB", "NFS1", "NFU1", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NMD3", "NME1", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN3", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD1", "OGT", "OIP5", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHPT1", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCD3", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGLUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POM121C", "PON2", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "RELA", "REPS1", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMND5A", "RNASEH2A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTF1", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD1", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAMP1", "SCAMP3", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC14L2", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGSH", "SGTA", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPRH", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC44A1", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT1A4", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE1", "SYNE2", "TAB1", "TAF10", "TAF2", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D24", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX2", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "TGS1", "THAP11", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THTPA", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TLN1", "TM7SF2", "TMCO1", "TMCO6", "TMED10", "TMED9", "TMEM109", "TMEM115", "TMEM165", "TMEM192", "TMEM201", "TMEM30A", "TMEM43", "TMEM70", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", 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0.0167623690719704 4.87621359223301 9.031553398058252 0.4125318500531191 0.1346012745180574 1.6566187440434876 0.4477283705000042 2.101542046986786 0.2228325403979826 0.0009918498188417 1.0 0.1073692926764015 0.0024789777341693 8.619476851357025e-06 +Poor head control 25 82 2.3892488676435453 0.0168828617205611 16.62864077669903 70.83495145631068 0.6551149189569596 0.4893764407721695 6.123760433086226 7.081833846449059 1.1601225008146194 0.3772060433763 0.003757337485579 0.4930885762521122 0.158596080293306 0.0001801941967283 1.6616884806435306e-06 +Neck muscle weakness 6 16 2.3870599171115043 0.0169837230284839 4.206310679611651 15.46359223300971 0.939049769317174 0.3360301393876674 2.1919222801274123 2.3742417714011115 0.9901989764800458 0.2887083620559018 0.0576324875298074 0.210390481437923 0.3834745889497097 0.1202502819228893 0.0968560278048493 +Young adult onset 4 13 2.386793587903055 0.0169960308157071 3.936893203883495 11.097087378640778 0.9326277418903632 0.2839315553797075 1.7793033594374144 1.2484130750505644 1.1998221427979727 0.2831359733121 0.0021151743166573 1.0 1.0 0.0066039089173338 0.0172708661402063 +Mania 6 14 2.384487768411831 0.0171029165525482 4.29126213592233 13.815533980582524 0.5633198814967983 0.4160552944360035 2.179476502394243 2.2801276272213657 1.0919629859527038 0.3085705503430486 0.0995145929386559 1.0 0.2544971315679337 0.0058861279901433 0.0005447761239901 +Delusions 7 21 2.372922220540372 0.0176479797958639 5.912621359223301 18.439320388349515 1.0629964764413025 0.2985925736346436 2.390745896997379 2.2281751696560335 1.2165016471530676 0.297036724651636 0.0029585779551093 0.1495431827221669 0.0426903814680922 0.0090982869347887 0.0002002807179905 +Hypocholesterolemia 5 8 2.3604092740262983 0.0182547829180945 3.2645631067961167 8.048543689320388 1.205673434171466 0.2055905154190861 1.747510449264718 1.0646904903887575 1.232151298114248 0.2464368010987078 5.432060717638784e-05 0.0583291306653072 0.1157837219692003 0.0001869772650567 1.5359091342738864e-05 +Ventricular arrhythmia 13 39 2.3533735718318587 0.0186039331282954 10.0 36.96601941747573 1.0415384316890377 0.3677574027458479 3.8522468541414527 4.8022861343455805 1.0152201826292362 0.3231502492090489 0.5232076688247249 1.0 0.2460090370927736 0.0920920135562724 0.0003181540596454 +Left ventricular hypertrophy 11 23 2.348805183630902 0.0188337580212325 7.567961165048544 23.54126213592233 0.6997255266541987 0.4097452846499351 3.537969183053948 3.034709621147107 1.2051726960058406 0.3398649994618895 0.3159020670218361 1.0 0.465472661331458 0.0713248886478035 0.0133209057752572 +Lower limb hyperreflexia 3 19 2.339313567729595 0.0193192110291207 4.975728155339806 18.783980582524272 0.2600152844191251 0.6088543741902349 2.7376187661222575 2.0071318665498907 0.7740605170564053 0.3012872593295428 0.0522581385465431 1.0 1.0 0.0284946927562346 0.208171350027034 +Dental crowding 7 29 2.329084120567199 0.0198546097475988 6.296116504854369 26.155339805825243 0.28394777902636 0.6218358539208668 2.999948942287107 3.4388056222812264 0.7660024895753724 0.3090045696932544 0.1684029225144945 1.0 1.0 0.1303045590934426 0.042764992597279 +Increased csf lactate 21 54 2.317409346865487 0.0204814436690232 14.563106796116504 50.03398058252427 0.4527108683296134 0.4236743568986457 6.839235611227043 5.521257303659666 1.4241114192986506 0.3526497741057939 0.0043254182396826 0.3383353600617786 0.0514257165812299 0.0012097644445398 3.135508043074704e-08 +Emg neuropathic changes 12 28 2.312961290710688 0.0207247674946986 6.915048543689321 24.58252427184466 0.5887299592537784 0.4208819793990807 3.046574831105746 2.544837804909062 1.1306803597402475 0.3318248802653038 0.0010114386490831 1.0 0.347293965666231 0.0040714376200731 4.181476323194264e-05 +Ankle clonus 2 12 2.3027476302335 0.0212930466177583 3.575242718446602 13.298543689320388 0.6380030192173395 0.4332907678689981 2.0352878876827107 2.085711402355677 0.9658483329689804 0.311402478823635 0.015943639086226 0.1336282364993428 0.2544971315679337 0.0364143419045942 0.1851338743881632 +Abnormal csf protein level 6 12 2.300856445161201 0.0213997466981206 4.434466019417476 12.20631067961165 1.1239853500963992 0.2260559983233297 2.11400242863219 2.084072511592451 1.241935948510828 0.248039542652958 0.0044056772369422 1.0 0.3090134871767957 0.0021528176338916 0.0022852196419379 +Depression 22 108 2.294089670976035 0.0217853485438528 21.866504854368937 102.23058252427184 0.3844987984674038 0.6518312597777748 6.663852964137664 9.29780935941184 0.7952008671962957 0.3502437860603438 0.0143123360055388 0.7024274045839494 0.0972145052330223 0.0447232655087089 0.0067621966568607 +Hepatomegaly 66 189 2.2884384518448764 0.0221120005423116 39.728155339805824 169.55582524271844 0.4089837357771489 0.5280564448988146 14.21621812446184 16.25283515367601 1.2317505616434137 0.3902252758923212 0.0003614311359056 0.5360257064276677 0.0288027940044867 0.0003388021766314 8.847887732324511e-09 +Exercise intolerance 13 34 2.2881652707056843 0.0221278983472428 7.589805825242719 32.94660194174757 0.6935647402019111 0.4794430320014746 3.6422804337959303 3.649320073231373 0.9787082553108852 0.3464451860868903 0.0388185457186626 1.0 0.1537720949657743 0.0309574270408548 0.0087167367443641 +Abnormal pulmonary interstitial morphology 5 32 2.282290384503143 0.0224722018611964 6.371359223300971 30.5995145631068 0.4103689768813533 0.4555813960836699 3.330566746297264 2.186076806332745 1.1224431747517174 0.329794447909787 0.0129124825333969 0.0535385420420041 0.0009706301918065 0.0123970480938125 0.1934037059954279 +Central scotoma 6 10 2.2807641835715065 0.0225624048495551 3.657766990291262 9.152912621359222 1.2790732929494344 0.2261272578521709 2.0233738200365714 2.077016218281829 1.2675536526802949 0.279373459017325 0.0785007730839361 0.1174219198717282 0.0264305171392709 0.133861047002827 0.0084254115710058 +Frequent falls 13 41 2.275238233435233 0.0228916424587632 8.643203883495145 38.75485436893204 0.6268988624161936 0.4831027569691007 4.0086529499315136 3.828305504664436 1.0909180744790496 0.3651237988976172 0.0036507756144449 1.0 0.1940719369188673 0.0042551679746705 0.0079981619879342 +Increased cerebral lipofuscin 4 5 2.266948513988564 0.0233933710916829 3.0970873786407767 5.118932038834951 1.0434065701738664 0.1270836154757583 1.1278862704044743 0.4599818751628888 1.7720117842909846 0.2267161680252343 3.402467421328227e-07 1.0 0.0903020002145616 1.6528806021689327e-06 5.177174829283688e-05 +Abnormal mitochondria in muscle tissue 11 25 2.26133050018375 0.0237387989041479 6.864077669902913 20.83252427184466 0.7962580997895766 0.3538054675594747 3.0570578650205316 2.639985737842691 1.2479322885734705 0.312408674687376 0.0032841853517826 0.1534769953785304 0.0046117674733532 0.0014933754194455 5.680160274180715e-07 +Poor eye contact 14 44 2.261085534919316 0.0237539609334616 9.774271844660197 38.25970873786408 0.6634270903175611 0.4886810186458507 3.917228340019005 4.329065002822378 1.0573021214973186 0.3538640004920722 0.008935600301169 0.290457955358921 0.0324304929106031 0.0018106785258558 4.40926405377349e-05 +Bilateral cryptorchidism 2 10 2.256584221887027 0.0240340671917087 2.6529126213592233 9.849514563106796 0.7102983026891413 0.4046694096755988 1.7935743620951357 1.043553840834269 0.9852608840174656 0.3101013475492273 0.0078387944068705 0.0053811669607165 0.0211645746663273 0.0184993148019339 0.1058637057364033 +Splenomegaly 22 96 2.2545945150462106 0.0241587920543888 20.660194174757283 86.74029126213593 0.5649049994066069 0.3835571498509289 6.419862077062851 7.868335701486235 1.546158503499524 0.3590721878602594 0.0186851222399343 0.6602490190294181 0.1730992628998134 0.0090261218863513 0.0007312053705791 +Bruising susceptibility 6 36 2.2374930337574868 0.025254134117544 6.973300970873787 29.92233009708738 0.7164216438132665 0.4493299188905011 2.7915903141815184 3.5959505822612523 0.9221467384175908 0.3249127615519124 0.0069028868703883 0.3655284832963578 0.235543931081911 0.0086321321861891 0.1914106410143156 +Proximal tubulopathy 12 27 2.235905146798316 0.025357985110584 7.269417475728155 23.25 0.6812729764745832 0.3939568357360496 3.269858916003623 2.8782959157530654 1.2124757185225692 0.3205652179980567 0.0062670440593274 0.1805193822238056 0.0076022823096988 0.0033331589242091 5.203608150807313e-07 +Cerebral inclusion bodies 6 16 2.2275782955447303 0.0259086493488307 3.844660194174758 13.655339805825244 0.5051551663301821 0.4226246963159299 1.8115448621120656 1.6612796655742368 1.090041660052819 0.3107400387490911 0.1105465258987554 1.0 0.2685126379615966 0.1840986918250508 0.0195746287107578 +Hepatic failure 17 50 2.2269086646465066 0.0259533786423933 12.25242718446602 48.050970873786405 0.7424989852941342 0.3814651163177168 5.527018274076851 5.448329576476532 1.3577793424610205 0.3539023729255708 0.0003708641585137 1.0 0.0155467923996434 0.0028877368652532 0.0003529172368585 +Abnormal vascular physiology 14 55 2.2222874702094284 0.0262638843760498 12.74757281553398 50.021844660194176 0.816183607478715 0.4136638745601454 4.907827009322534 5.622165606934028 1.2216480011219424 0.371091913776798 0.0773710167906849 0.5513213948028619 0.2203360283517562 0.052437625084942 0.0185164852813002 +Hyperactive patellar reflex 2 8 2.2222235638957284 0.0262682007557517 2.6019417475728157 7.691747572815534 0.3382848613247674 0.4892243591973106 1.5908708357450425 0.9973897264247332 0.9635506080031846 0.3114172566013329 0.0203954716413504 1.0 1.0 0.0031665778749487 0.0220005392397008 +Scotoma 6 13 2.220750892821099 0.0263678383293639 4.189320388349515 12.196601941747574 1.1271039056750725 0.2779036999445621 2.1128553643245884 2.0698220238662226 1.1901076059375446 0.2884356618441315 0.1513244135942271 0.1690349275366953 0.0543070281832774 0.2453334774508567 0.0413463237345707 +Cns demyelination 3 14 2.220727984241308 0.0263693908476672 4.330097087378641 13.868932038834952 0.932085489476866 0.3543850979390085 1.8689509518649636 1.4505793369743718 0.9962875819434424 0.3044831103069028 0.0018757503369794 1.0 0.2544971315679337 0.0058861279901433 0.059428299109383 +Optic disc pallor 21 58 2.2186536301492668 0.0265102979486444 14.480582524271844 48.592233009708735 1.02733963234224 0.3801436604957769 5.692535706296588 6.181615230530596 1.3595924408188145 0.3692839687174071 0.0182650039748019 0.1070124290166615 0.0271836119186563 0.0680367601336092 4.570909091306546e-06 +Abnormal pupillary function 2 8 2.218214534134656 0.026540208218406 1.7985436893203883 6.25 0.9459174425459445 0.2892194993230557 1.1928988171245156 1.7202745886032773 1.109204161812943 0.2732247962160634 0.015943639086226 1.0 1.0 0.0364143419045942 0.1851338743881632 +Abnormality of hepatobiliary system physiology 25 82 2.206080880801274 0.0273783371377336 18.737864077669904 78.23543689320388 0.6753867917166245 0.4584905924436965 8.191827759406172 8.347745847320367 1.279744288983872 0.374212423907768 0.0013161045857663 0.5094567973032235 0.014606576470738 0.00027913666766 4.210021175160091e-05 +Bilateral tonic clonic seizure 19 92 2.204005815104205 0.0275239351306149 16.54126213592233 83.87864077669903 -0.1036545284961206 0.6620244011720979 6.822346659397593 8.994865315056538 0.7668565661638337 0.3104656168106364 0.0020504289546676 0.6570218147986038 0.1694210214699924 0.0011151747442132 0.0071147233375736 +Shuffling gait 2 11 2.195213974973204 0.0281482522706244 2.395631067961165 11.230582524271844 0.6109447518071078 0.4679989342941459 1.905862274541426 1.6198815282358896 0.8086665925844128 0.2924773789974313 0.0941229184977135 1.0 0.2473900535744361 0.1586010561439087 0.17296881871654 +Hallucinations 15 49 2.190515759099509 0.0284868531619182 11.20388349514563 45.44660194174757 0.6705549628539956 0.4221278622600144 3.902598644570227 4.462852401771342 1.2595119979903464 0.3693437289960082 0.0076006676011307 0.3714211816184957 0.0680937326262565 0.0315322937435866 0.0009591698163975 +Increased serum lactate 30 107 2.1807874406523227 0.029199141944205 28.99514563106796 103.9126213592233 0.2156320103365802 0.4835633979758786 13.01418105275692 9.239117761559864 1.4606133548257267 0.3784654233889921 0.0101968591084461 0.5534251352687798 0.0802569171683539 0.0008467818693548 5.17577105418061e-08 +Abnormal atrioventricular conduction 5 13 2.1767290384289546 0.0295007903499424 3.3058252427184467 13.5 0.803490943489636 0.4083737460619471 2.0033140136835907 1.766049840416445 0.7753827866029901 0.2782630065474476 0.5109665768791669 1.0 0.3220142659994904 0.2541801412848018 0.012842786798321 +Abnormal aortic valve morphology 11 46 2.175454277282045 0.0295960908971761 8.643203883495145 40.00970873786408 0.3771375227817258 0.6013013640738508 3.3791734249815333 4.169922691726094 0.7682658177529654 0.3210565311311592 0.0743621996666256 0.4536421562781493 0.3469082852103691 0.1963403301367952 0.0223719099634021 +Psychosis 10 33 2.163598182123358 0.0304952011810974 7.441747572815534 29.73543689320388 0.4742861565216377 0.5201326315543127 2.950893373754939 3.867389997355917 0.8779517344338251 0.3210463988305211 0.1396123361993037 1.0 0.5093893069309869 0.102468551885206 0.0029908235432051 +Fluctuations in consciousness 5 8 2.1585910906037302 0.0308819045684829 2.871359223300971 7.104368932038835 1.0899440920546752 0.2545542015295898 1.680977263462837 1.481694234866534 1.1451509420956862 0.2733842157028129 0.0417999766536677 1.0 0.0135177788357734 0.0096601558647598 0.0114804089950453 +Loss of speech 6 20 2.1582178449386755 0.0309108986164858 5.453883495145631 19.1626213592233 0.4726173662677797 0.3013153148889984 2.223071754411353 1.8941045281154043 1.521023928928509 0.3006842241053739 0.0057602811574553 1.0 0.3284235846140172 0.0171039247471448 0.0035404261882341 +Vascular skin abnormality 21 128 2.152736622459773 0.0313393835576405 24.946601941747577 116.29611650485435 0.7757412099244599 0.4861695283888829 8.070806982353375 12.284834935174542 1.190653202647226 0.3932244292288712 0.0075904815947112 0.4832605784155284 0.2336460704707805 0.0040809862642003 0.0306522814628862 +Prenatal maternal abnormality 5 15 2.1505175994236403 0.0315142953991061 3.2184466019417477 13.143203883495143 0.9929636287681164 0.3563834047543391 1.88526465772658 1.4026249411092802 0.7410557762145566 0.2726392168397587 0.0311375328454698 1.0 0.4805273996536341 0.0237302495927712 0.1132650445959035 +Postural tremor 3 16 2.140875831110989 0.032284052657338 5.194174757281553 17.851941747572816 1.214872214945056 0.2487017685351703 2.341305968762478 2.2981463861426747 1.2391489410765593 0.2821199379659175 0.0048303145699814 0.1690349275366953 0.0543070281832774 0.0144863601278662 0.0413463237345707 +Increased serum pyruvate 14 37 2.137895641936173 0.0325252140443945 9.303398058252426 32.64563106796116 0.7845790996019184 0.387018609503293 3.945341127018032 3.24570744750092 1.0586848930233297 0.3138975633269482 0.0012351070598104 0.1955906255262107 0.0009655190728592 0.0007985440380067 2.305086213004741e-08 +Abnormal macular morphology 5 27 2.1333089890003003 0.0328993873121346 5.881067961165049 26.936893203883496 0.2429090782086877 0.4668963917414836 3.102290232183583 2.9305717090684964 1.1278643921545293 0.335754410396833 0.116556753927922 1.0 0.0187923503468816 0.1139631559029858 0.4183160321037849 +Abnormal metabolic brain imaging by mrs 4 16 2.1245165460465936 0.033626973974568 4.606796116504855 16.54854368932039 0.7235353195513555 0.4019359214719802 2.5477483733613684 2.1144608015049493 1.0143737900681629 0.2966800307492503 0.0204436144926609 1.0 0.275422289319612 0.0011455603346848 0.0220710469799609 +Focal t2 hyperintense brainstem lesion 11 22 2.1217511135743625 0.0338586438590509 5.745145631067961 17.558252427184467 0.7787968952644161 0.3563659539921697 2.720936576360794 2.4403574571781053 1.1656572167307155 0.3009968442621839 0.0018757503369794 0.1336282364993428 0.0030035335028325 0.0058861279901433 1.067217057788887e-06 +Abnormal brainstem mri signal intensity 11 25 2.11944092393319 0.0340532213672652 6.252427184466019 20.32281553398058 0.9466857218441096 0.334812084954676 2.9078682900486936 2.582646312540884 1.1241621585657078 0.2967087697298931 0.003633380055843 0.1573929974646098 0.0049847932658442 0.0110616415512106 6.457957003828631e-06 +Focal segmental glomerulosclerosis 3 21 2.1171538534458505 0.0342467923939964 5.546116504854369 21.611650485436893 0.6827474585317643 0.4280798303492368 2.9461690553889595 2.0180400455423047 1.030587218054049 0.3284604148463202 0.0399573695699691 0.1843129003022452 0.0643053609617777 0.0199990348372571 0.058494764718068 +Pedal edema 1 9 2.1050414322746205 0.0352877016525086 2.092233009708738 7.211165048543689 0.6115824815809859 0.289867756561444 1.3297338459429695 1.219410808682535 1.3115580791228945 0.2762999280116011 0.0734939527005626 0.1133242047904145 0.024621467016068 0.1258256892179061 0.3574503952486402 +Hypothermia 4 10 2.1038986423442148 0.0353872894482085 2.4174757281553396 9.49271844660194 1.0856169578047503 0.2588610618328691 1.611694349619475 1.8201795996814751 1.0634596616937388 0.2538467530049644 0.0591475015489903 1.0 0.0195190580371743 0.0164697860130212 0.0041129787740785 +Disproportionate short stature 8 24 2.102617104367237 0.0354992535411187 8.58252427184466 24.70145631067961 1.4449047806081987 0.2464238748623315 3.3320283680556178 3.793287097673045 1.0910515137563812 0.2952991105687103 0.1987370305866761 1.0 0.5707078240420155 0.1608949281406532 0.0267610812774429 +Abnormal placenta morphology 3 9 2.100872965693054 0.0356521191406167 1.944174757281553 8.475728155339805 0.7648192021909558 0.3426805830523109 1.4036326133106245 0.983797478904342 1.0207702392187767 0.275511162241509 0.3185082358444843 1.0 1.0 0.4108142183097444 0.0193421266882966 +Abnormal lower motor neuron morphology 1 8 2.100421140608312 0.0356918109470651 2.1771844660194173 8.701456310679612 0.8468629004048428 0.2893246976958152 1.3759952567341256 1.207057649999096 1.1584035743641086 0.2695692447215745 0.0685959008552041 0.1092078710908161 0.0228657680446322 0.1179126451543179 0.3397194637657424 +Ragged red muscle fibers 4 18 2.0998317275295064 0.0357436461979732 5.233009708737864 17.730582524271846 1.450228655394427 0.2143723456093393 2.356374883616516 2.3878203593303375 1.2019998086948689 0.268108115907532 0.029336552338356 1.0 0.0519022265935445 0.0132790770586149 0.0376047003110277 +Personality changes 5 17 2.09456575332636 0.0362096122289932 4.235436893203883 16.20873786407767 0.716641708966708 0.4361664780008399 2.2513009299259603 2.2727002372019856 0.9467269936740988 0.3182188186141179 0.0274187927150404 1.0 0.0495371989584494 0.012137922245926 0.0088977066355322 +Dilated cardiomyopathy 13 46 2.0902470681380145 0.0365956114144085 10.635922330097088 39.97330097087379 0.5129450772756666 0.4904456922847132 4.591409335191949 5.064800073369426 1.060082827410621 0.3517020619562892 0.5937927552751592 1.0 0.6651472144860665 0.2913112691993593 0.0011946773350447 +Photophobia 11 41 2.089190917945342 0.0366905406524151 8.201456310679612 36.398058252427184 0.4678600054481162 0.5820727111270125 3.604298649244484 3.1999387306793547 0.8235485247156009 0.3378012969761652 0.0210831715291666 0.4407102053841196 0.3296956834902948 0.0769650581839678 0.0780727469028016 +Abnormality of extrapyramidal motor function 15 73 2.0774696331184943 0.0377582351568479 17.723300970873787 74.23058252427184 0.6611914449106878 0.5008095396366101 5.517064505158221 6.985611887807198 1.1554912414277594 0.3847143245763222 0.2801588578597231 0.2437255430960846 0.304109364787458 0.539054031168056 0.1173141136099386 +Delayed puberty 8 54 2.070050442399008 0.0384476210095394 10.66019417475728 52.48300970873787 0.1812625564567306 0.6563167649934863 5.354978444125938 4.103893802197075 0.7435802913779851 0.3144438568841715 0.053381603202757 0.1026204299336703 0.0998900379960956 0.0617583071786082 0.0573475824865733 +Abnormality of skull ossification 5 14 2.070040465155895 0.0384485552432636 4.366504854368932 12.970873786407768 1.1881205011944458 0.2637442069575459 1.99249670608582 1.4511884027191762 0.8848235988748787 0.2626440236811827 0.0204436144926609 1.0 1.0 0.0082083083177425 0.0050954027488052 +Hypoketotic hypoglycemia 3 8 2.0620843496629613 0.0391997060871129 2.3470873786407767 7.560679611650485 1.365087782487965 0.212332843161917 1.4324316558480732 0.6923349575659244 0.8002406012991511 0.2265642620801705 0.0147099496631327 1.0 0.0988756314725496 0.026793282710744 0.001326906313577 +Incoordination 22 76 2.061907606043843 0.0392165332622662 15.859223300970871 69.11650485436893 0.6868183945924522 0.4621230815272417 5.5138472973140855 6.676725217396416 1.1752874861922693 0.3755559385684158 0.0001703355499882 0.5470847745067343 0.2154098093634822 0.0007255596637295 0.0033165467511536 +Hypokinesia 3 13 2.057711983845673 0.0396177893142175 3.3228155339805827 12.177184466019416 0.7049731134993743 0.4050382900786843 1.785911378374969 2.0633566382130173 0.9326231482443949 0.2932516715732374 0.3862694656938347 1.0 0.2329741481650856 0.490074751374992 0.0432317268333426 +Abnormal social behavior 23 75 2.0576398851342628 0.0396247149488686 16.796116504854368 65.80339805825243 0.6678301735588785 0.4940185804874849 5.994105880514205 6.839540104535511 1.1033956384068455 0.3774724921329495 0.0234912514997625 0.5341386253553418 0.2007845961680959 0.0162022182989472 0.0001130880239894 +Fetal distress 13 28 2.053289592716598 0.040044499618371 6.694174757281553 23.524271844660195 0.315106981366531 0.4342915849252123 3.1374136043562535 2.920781449478041 1.1333892319914325 0.2945358880670072 0.0044056772369422 0.1651718851687308 0.0057841877037216 0.0132790770586149 1.3895801225240888e-06 +Pathologic fracture 3 18 2.048673991204472 0.0404940040959487 4.257281553398058 15.072815533980584 0.983166532607372 0.3143076297274698 2.133145812327421 2.2800397788540345 1.0713003315034937 0.2893419439464214 0.029336552338356 0.1651718851687308 0.0519022265935445 0.0132790770586149 0.1158015503640465 +Abnormal auditory evoked potentials 5 9 2.04515274487929 0.0408398016164091 2.837378640776699 8.45388349514563 0.8113355275163785 0.2966376606156203 1.5470802196866602 1.3128600166506037 1.1722229382642326 0.2813987538538041 0.0459284510874455 1.0 1.0 0.0805697230417203 0.0138168318064428 +Corneal opacity 20 57 2.0384779242842463 0.0415021602856984 15.480582524271844 53.95631067961165 0.9517965339960472 0.3644495779961974 5.277458167452316 6.791845051563607 1.5225460520633525 0.3686110256368129 0.0453788867516176 0.5858009342132465 0.102693735264191 0.1629616263999687 0.0043057066920892 +Stroke like episode 3 5 2.035895255205436 0.0417608743859503 1.9320388349514563 5.347087378640777 0.7802983779647638 0.3377286829697849 1.3402806250303152 1.5433591727314462 1.1185957061594276 0.2970042406174105 0.256394918871775 1.0 0.1486636480545473 0.0603828760130106 0.0076060652236079 +Orthostatic hypotension due to autonomic dysfunction 4 10 2.0246039431497795 0.0429080490429265 2.8689320388349513 9.026699029126211 0.6690910568198125 0.3153802844238013 1.4405048418053912 0.8105887688186777 1.185865447592776 0.2910194211316744 0.0015998581819158 1.0 0.1241196507421894 0.0039601236721776 0.0003502537372228 +Motor neuron atrophy 2 21 2.023300277083208 0.0430421983511843 5.410194174757281 22.424757281553397 0.8356342611289532 0.3959768073616548 2.754377444710008 1.6813276911909307 0.954775311801755 0.3176984078794489 0.0549135737484515 0.2067156970668985 0.0115168854492612 0.1150831466071068 0.433858789515263 +Abnormality of the biliary system 31 121 2.022997497881984 0.0430734054869701 24.728155339805824 113.4878640776699 0.4226772043353868 0.5416117734931738 8.513489210598458 10.938368752781027 1.0946055307638114 0.3805906621326833 0.0018166760940149 0.7038348627595198 0.2292558737129506 0.0013434023423119 5.153328694925791e-05 +Dermal atrophy 5 30 2.0215108953812706 0.0432269056314722 5.320388349514563 26.895631067961165 0.7910895542770026 0.4477466139002859 2.6272049167180267 2.645986214694848 0.8422228280317593 0.3177571120785681 0.0372032513718843 1.0 0.4999495019072014 0.0950757237496321 0.1378034958599644 +Rhizomelia 4 11 2.0145141720978224 0.0439555784605489 4.276699029126213 11.868932038834952 1.3783619481702345 0.228956695884812 2.09278482575067 1.6655579622091714 0.936017394236602 0.2616202806826952 0.1882248491254931 1.0 0.3534667347825532 0.0953125935026511 0.0683826395880997 +Respiratory distress 19 57 2.0105311502209986 0.0443750027403315 12.805825242718448 52.09466019417476 0.6386570898760532 0.4437575130669694 5.288397728288474 5.051988998968333 1.24726945526474 0.3693239953771813 0.028468775915089 1.0 0.1322401346903697 0.099352947654332 0.0050036983612911 +Low frustration tolerance 1 9 2.009118407499847 0.044524577953658 2.2402912621359223 8.861650485436893 0.6170800437496735 0.4474642212406593 1.8402268519458895 1.0394103977385205 0.9109780988264436 0.3087684537640934 0.0303360476395803 1.0 0.1405588989726414 0.0541048590842698 0.1778574078192432 +Nyctalopia 11 34 2.0078247668600957 0.0446619160200953 8.08252427184466 30.20145631067961 0.1747687144712608 0.6672287802995144 3.591114362689628 3.600930006024196 0.7439274513131711 0.3093915865456161 0.2719850195840252 0.3859195782313845 0.6315431740367674 0.4563197785336553 0.1319614615085023 +Abnormality of coordination 77 340 2.0071143472961026 0.0447374888956977 65.05339805825243 312.07766990291265 0.3537206479527984 0.7134221988982268 20.398983010696288 29.808593053234937 0.9921840157004412 0.3756105558441653 0.005908998099877 0.1638475281799924 0.1355714060075813 0.0050058968212737 5.392138231742927e-06 +Abnormality of femur morphology 15 74 2.005038624509398 0.0449589179982794 17.20873786407767 66.68203883495146 0.8363246416857221 0.4265359075043799 5.791282481104246 7.777760660479065 1.2398669594969238 0.3848538433547022 0.0521027875850794 1.0 0.8447275290323855 0.0178575058870057 0.0256304763642809 +Limb ataxia 5 22 2.001418397073862 0.0453473197279714 6.597087378640777 24.114077669902912 0.989869123864314 0.3154216467413447 2.5039369509835696 2.8496458430585005 1.1323309577692284 0.292147514752726 0.0186961014902875 0.2391950786393786 0.1063833340177388 0.0510731923964723 0.0222951690304878 +Resting tremor 4 18 1.9991428187147071 0.0455929033632866 5.026699029126213 19.063106796116504 0.4260292617298505 0.4633026869029207 2.2429535349404746 2.4427221124580822 0.9815581137258528 0.3036505506177132 0.0376968160993815 1.0 0.3347729381598622 0.0815041572972921 0.0538789205814144 +Eeg with focal spikes 1 6 1.9852289712004991 0.047119002419329 1.199029126213592 4.611650485436893 0.2009379318587673 0.3945439266933198 1.2224434504069814 1.009498671202671 1.1758184518685515 0.2899583413391119 0.0121723982982892 1.0 1.0 0.0222658144313338 0.0803258352566255 +Neuronal loss in central nervous system 6 13 1.9835100349177088 0.0473104872868943 4.087378640776699 12.526699029126211 0.982175765643533 0.2959736314179056 1.731247914675439 1.993135251988059 1.1236470294677874 0.2967990988512021 0.0016557742469122 1.0 0.2473900535744361 0.0052222662915419 0.0132180269039013 +Abnormal csf metabolite level 21 60 1.982486237320512 0.0474248462269093 15.62864077669903 56.38834951456311 0.3728365451013375 0.4594620050205593 7.183479908053284 5.909073177714687 1.318852118504194 0.3560984107552507 0.0104453913864044 0.3916268401133314 0.0798251786179041 0.0038802950355105 6.716882283541848e-07 +Temperature instability 4 10 1.9819673544471643 0.0474828945212542 2.563106796116505 8.077669902912621 0.5786926336202384 0.3539234625201496 1.6976277160735205 1.200237196527885 1.1389671471549596 0.2898062051573807 0.0039973815504214 1.0 1.0 0.0096601558647598 0.0016660348526245 +Parkinsonism with favorable response to dopaminergic medication 2 10 1.9761267965984035 0.0481404181644233 2.655339805825242 10.1626213592233 0.3985424111712905 0.4433567173097827 1.6183551613355214 1.1866003172685575 0.9671703366197402 0.2883508038886271 0.0046437067491223 1.0 0.172526836456327 0.0111687214620054 0.068509275445109 +Muscle fiber atrophy 8 22 1.9738537197745172 0.048398378448035 5.444174757281553 20.281553398058257 0.7686173455615849 0.4552894087545087 2.6272082803045267 1.888480540541262 0.8113647632820095 0.320700919049039 0.5519087416189806 0.1918484459181316 0.3534667347825532 0.6695968290547825 0.0218949055651906 +Horizontal nystagmus 8 26 1.9712191706056152 0.0486988120654747 6.274271844660194 23.053398058252423 1.1086320165192889 0.2915732095622053 2.6115907074401723 2.1860242554539786 1.3408731048130669 0.3129960018850027 0.0023110057580336 0.2213151554805003 0.0916480459892936 0.0088741125605978 0.0141919878361578 +Emg chronic denervation signs 8 15 1.9704657360989355 0.0487850181553251 4.550970873786408 13.815533980582524 0.6176194543661773 0.3415909714455588 2.199917039284479 1.6085184210885628 1.2249413291120588 0.2985007469873863 0.0078387944068705 1.0 0.2033176172301104 0.0184993148019339 0.0007662488934102 +Progressive psychomotor deterioration 5 9 1.9647448652191968 0.0494437743990912 3.349514563106796 8.320388349514563 0.5379615244672443 0.2176134167318772 1.5053866894387542 0.6226094824456632 1.5848775742530583 0.2457660654605461 0.0174535696320652 1.0 1.0 0.0024789777341693 8.619476851357025e-06 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f907652c6ac3fdb30823238084e0e94bb196c079 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 4669, + "title": "Average number of proteins per term", + "value": 25.713000642535874 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5102376c698f5abcdc9e5717783e037286017826 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..eaf6a4dcadf33411351f92cec568db2deb8a1c12 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1781 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mental deterioration 0.5667609175963404 3.8729281293839337 0.0001075355463802 0.3947480515341001 0.0039534131184977 103 Q9BQE5,Q9NZJ7,Q14108,Q10713,P35670,O15118,O76024,P16278,Q96RL7,P21964,Q8WVX9,O75503,O43681,O95140,O96008,P50897,P21912,Q5XKP0,P20700,P22626,Q9NQZ5,P04062,P03886,Q13510,P54802,P00403,P61916,P07602,Q8NHS3,P35637,P27544,P17900,O60313,P05067,O95470,Q9NPL8,Q9Y287 37 +Dementia 0.6095630852495715 3.3040199064142266 0.0009530906441486 0.9883459577298804 0.0171813908012736 62 Q9NZJ7,Q14108,P35670,O15118,O76024,Q96RL7,Q8WVX9,O43681,O96008,P21912,P20700,Q9NQZ5,P04062,P03886,Q13510,P00403,P61916,P07602,P35637,P27544,P17900,O60313,P05067,Q9Y287 24 +Abnormal circulating lipid concentration 0.5558446814744367 3.16791845171784 0.0015353458034601 0.9992337777460089 0.0256936543238546 77 Q9NZJ7,Q03252,Q9NVI7,P56589,P22830,P37268,Q9UBM7,P23786,Q8N511,P50402,P49257,O75431,Q9Y6B6,Q15392,Q9BTV4,P40855,O75381,O43772,Q9UJS0,P61916,P49748,P07602,O75844,Q9Y4P3,Q15800,Q14739,P02545,P40939,O95470 29 +Cognitive impairment 0.4465493709760728 3.1041542183047133 0.0019082383662927 0.999866054364946 0.030097051007105 182 Q9BQE5,Q9NZJ7,Q14108,Q10713,P13473,P01889,P35670,O15118,O76024,P16278,P56589,P12235,Q99720,Q96RL7,Q969G3,P21964,Q8WVX9,O75503,O43681,O95140,O96008,P50897,P21912,Q5XKP0,P40855,Q9Y2R0,P20700,O75381,P22626,Q9NQZ5,O00255,P04062,Q6DKK2,Q6PGP7,P03886,Q13510,O75352,O43819,Q9UJS0,P54802,P00403,P61916,Q9Y619,P07602,Q96T60,Q8NHS3,P35637,P27544,O95470,P17900,O60313,P05067,P07196,Q9NPL8,Q9Y287 55 +Abnormal circulating cholesterol concentration 0.6580146951192114 3.097893463014074 0.0019490148036855 0.9998893158188196 0.0301832544695636 32 P50402,Q9NZJ7,Q8N511,P07602,P02545,Q9NVI7,O75431,Q15800,Q14739,Q15392,P37268,Q9UBM7,Q9UJS0,Q9BTV4 14 +Muscle abnormality related to mitochondrial dysfunction 0.6126436944514515 3.008382357733731 0.0026264246548215 0.9999953512332808 0.0390534290234452 38 Q9Y2R0,O43676,Q9Y6M9,O96000,Q8TB37,Q86Y39,Q8N183,Q9UBX3,Q53H12,P03886,O60313,O75380,P12235,Q9Y375,Q9NPL8,P00403 16 +Myoclonus 0.4897735283757991 2.948606620640552 0.0031921000840886 0.9999996711793692 0.0451633796745755 98 Q9NZJ7,Q14108,Q10713,Q03252,Q8NI60,Q01105,P13073,Q969G3,O75503,O96008,P50897,Q9NWS8,P00374,Q9NQZ5,P04062,P03886,Q13510,P00403,P07602,Q96T60,Q9H078,O14656,P27544,Q9UBX3,O14773,P05067,Q9NPL8 27 +Ventricular hypertrophy 0.5936498624454151 2.8478587118434993 0.0044014460284509 0.999999998863952 0.059913561244424 36 O75880,Q07021,O43772,O00255,O75844,O75431,Q13724,P40939,P23786,P21912,P03886,Q6NUK1,P10253,P02545,P12235,P00403 16 +Supranuclear gaze palsy 0.7319418600824134 2.8133833341317236 0.0049023171610829 0.9999999998916016 0.0659623020896142 19 P61916,Q9NZJ7,P07602,P04062,O15118,Q99720,Q96RL7 7 +Phenotypic variability 0.4655591153049838 2.7820204233279666 0.0054021640417705 0.9999999999896194 0.0714524190114066 105 Q9NZJ7,Q8NI60,Q9H061,Q53H12,Q6P4A7,Q969G3,Q15427,Q70HW3,P21912,Q9NWS8,P00374,O15121,P03886,Q13510,O60313,P00403,Q9NR77,P07602,Q8TB37,O14656,Q9Y375,P17900,P02545,O95470 24 +Clumsiness 0.6711900142253909 2.7499164537729124 0.0059610461103465 0.9999999999992476 0.0779611324627674 24 Q9NZJ7,Q9NR77,P07602,P35670,O14773,Q13510 6 +Variable expressivity 0.5011687038617417 2.7352759344762365 0.0062328003721476 0.99999999999979 0.0806120358381095 81 Q9NZJ7,Q8NI60,Q9H061,Q53H12,Q6P4A7,Q15427,Q70HW3,Q9NWS8,P00374,O15121,P03886,Q13510,P00403,Q9NR77,P07602,Q8TB37,O95470,P17900,P02545,Q9Y375 20 +Progressive neurologic deterioration 0.6890942357775356 2.731191973782969 0.0063105700627801 0.9999999999998544 0.0811681862895879 22 Q9NZJ7,Q10713,P07602,O43681,P04062,P21912,P16278,Q5XKP0,P54802,Q9NPL8,Q9Y287 11 +Hyperesthesia 0.9637538634447872 2.7189026254124 0.0065498886993138 0.9999999999999528 0.0837847406495788 2 P07602 1 +Toe walking 0.6394494965872171 2.681999507896934 0.0073183567432379 0.9999999999999988 0.0913620524978027 27 P50402,Q9NZJ7,P07602,O43681,P35637,Q99720,P02545,P40939,Q9BTV4 9 +Intracellular accumulation of autofluorescent lipopigment storage material 0.9519527957291364 2.6688291169571077 0.0076116165002524 0.9999999999999996 0.0920690089110845 2 O14773 1 +Decreased activity of mitochondrial complex i 0.5684161066181932 2.665195424087931 0.0076943595081795 0.9999999999999998 0.0925901148033254 38 O43676,Q9Y6M9,O96000,Q8TB37,Q86Y39,Q70HW3,Q8N183,Q9UBX3,P03886,O75380,Q9Y375,Q9NPL8,P51970 13 +Elevated pulmonary artery pressure 0.6074098711648502 2.6187772699150833 0.008824554422733 1.0 0.103522222612413 30 P00403,Q14108,P01889,O96000,P04062,O75844,P03886,P02545,Q6NUK1,Q8IZA0,P51970 11 +Macular degeneration 0.7833968303734389 2.6041995091442747 0.0092089133360804 1.0 0.1069562596173122 13 P51648,P04062,P50897 3 +Epidermal hyperkeratosis 0.930879460522616 2.578738310080946 0.0099161875444777 1.0 0.1126488555843471 2 O75844 1 +Severe failure to thrive 0.930879460522616 2.578738310080946 0.0099161875444777 1.0 0.1126488555843471 2 O75844 1 +Prominent umbilicus 0.930879460522616 2.578738310080946 0.0099161875444777 1.0 0.1126488555843471 2 O75844 1 +Aplasia hypoplasia of the colon 0.930879460522616 2.578738310080946 0.0099161875444777 1.0 0.1126488555843471 2 O75844 1 +Mitochondrial myopathy 0.5914374735117267 2.560850253601332 0.010441635194837 1.0 0.1180435707619719 31 O43676,Q9Y6M9,O96000,Q8TB37,Q86Y39,Q8N183,Q53H12,P03886,O60313,O75380,P12235,Q9Y375,Q9NPL8,P00403 14 +Hypertrophic cardiomyopathy 0.4403389301088976 2.5537811574632183 0.0106560207984043 1.0 0.1195984642013217 122 P13473,P01889,Q9NVI7,Q9H061,Q9BUB7,P16278,P12235,P50402,O43676,P09493,Q9Y6M9,Q8N183,Q96I36,P21912,Q5XKP0,Q9BTV4,O96000,Q86Y39,P03886,P10253,O75380,P54802,P00403,O60313,Q13423,P49748,Q9P0J0,Q9Y4P3,P53701,P02545,Q96IX5,P40939,Q9Y375,Q9NPL8 34 +Facial capillary hemangioma 0.9207642596234888 2.5351875413771574 0.0112387139850409 1.0 0.1238457266202944 2 P16435 1 +Abnormal cellular phenotype 0.4101157558267069 2.5349404108214353 0.0112466455530102 1.0 0.1238457266202944 200 Q9NZJ7,Q14108,Q9BUB7,P13073,P23786,P21964,O43676,Q9Y6M9,O75503,Q16134,Q70HW3,P21912,P51970,P09601,Q9Y2R0,O43772,O96000,P04062,Q86Y39,Q6PGP7,P03886,Q13510,P02545,P00403,P49748,P07602,O75844,Q9P0J0,Q9Y375,Q9UBX3,Q92643,Q14739,O14773,P40939,P00813 35 +Micrographia 0.919921326215225 2.531549318766853 0.0113559846198594 1.0 0.1240597992125535 2 P04062 1 +Abnormality of the mitochondrion 0.454553829430167 2.5302249877424474 0.0113989406430039 1.0 0.1240597992125535 97 Q9BUB7,P13073,P23786,P12235,Q96CU9,O43676,P82663,Q9Y6M9,Q16134,Q70HW3,Q8N183,P21912,P51970,Q9Y2R0,O43772,O96000,Q86Y39,P03886,O75380,P00403,P49748,Q9P0J0,Q8TB37,P35637,Q9UBX3,P40939,Q9Y375,Q9NPL8 28 +Social and occupational deterioration 0.918235459398702 2.5242687252799647 0.0115939264425906 1.0 0.1253732035889538 2 Q9BQE5 1 +Negativism 0.918235459398702 2.5242687252799647 0.0115939264425906 1.0 0.1253732035889538 2 Q9BQE5 1 +Abnormal retinal artery morphology 0.6732702935040633 2.5240792791325335 0.0116001764725697 1.0 0.1253732035889538 20 Q9NZJ7,P10619,P21964,P07602,P03886,P17900,P16278,Q13510 8 +Schizophrenia 0.654930127482878 2.5213418230345193 0.0116908223444152 1.0 0.1260610843558305 22 Q9BQE5,Q9NZJ7,P16615,P07602,P04062,O76024 6 +Hypertrophic nerve changes 0.9143017701601532 2.507259171165174 0.0121671462429273 1.0 0.1298725731034811 2 Q9NR77 1 +Bulbar signs 0.7817497810831979 2.5067879722314226 0.0121833769585188 1.0 0.1298725731034811 12 P03886,Q99720,P04062,P07602 4 +Osteoarthritis 0.798176011942982 2.50165522950512 0.0123614238516545 1.0 0.1308741223659295 11 Q14108,P01889,O75844,P04062,P35670,P02545 6 +Hypersplenism 0.8279090332278234 2.483219631079129 0.0130200783113727 1.0 0.137225159448757 9 Q14108,P04062,P07602 3 +Cardiac conduction abnormality 0.5942717582035599 2.4715883671949133 0.0134514302127526 1.0 0.1405343520262953 29 P50402,O43772,P21912,P03886,P02545,Q9H490,P23786,Q9BTV4,P00403 9 +Atlantoaxial instability 0.9058724360775467 2.4707088471374674 0.0134845555167659 1.0 0.1405343520262953 2 Q9NWM8 1 +Abnormal pelvis bone morphology 0.905872436077548 2.4707088471374674 0.0134845555167659 1.0 0.1405343520262953 2 P16435 1 +Abnormality of the cerebrospinal fluid 0.416867160086831 2.461989239717104 0.0138168811937877 1.0 0.1425247839898131 155 Q9NZJ7,Q8NI60,Q10713,Q03252,Q9HC21,Q8TAA9,P13073,Q6NUK1,Q9H490,Q9UBM7,P23786,O60508,Q969G3,Q96CU9,P21964,Q15427,O43676,Q9Y6M9,O43681,O95140,Q8N183,Q96I36,O95202,Q9NWS8,Q15392,P40855,P08236,P51970,P20700,O96000,P04062,P82930,Q86Y39,P03886,O75380,P16435,P00403,Q9NR77,P07602,O43505,Q9P0J0,Q8TB37,P53701,O60826,Q9Y375,Q9NPL8 46 +Abnormality of pulmonary circulation 0.5521384662283211 2.450313543466 0.0142731865018099 1.0 0.1458228444728413 34 P00403,Q14108,P01889,O96000,P04062,O75844,P03886,P02545,Q6NUK1,Q8IZA0,P51970 11 +Sensorimotor neuropathy 0.5673140944750945 2.4408064078930756 0.0146545082553981 1.0 0.1484206053025032 32 P05023,P41440,Q9NZJ7,Q9NR77,Q9Y2R0,P07602,P03886,O60313,P40939,P00403 10 +Bull s eye maculopathy 0.898567013205954 2.4389203697708424 0.0147312139828974 1.0 0.148874541312009 2 Q9UM00 1 +Abnormal biliary tract morphology 0.6162731810743475 2.4360062786644487 0.0148504267575253 1.0 0.1497551674533171 25 P09601,Q9NZJ7,Q14108,P07602,P04062,Q14739,P02545,Q5XKP0 8 +Abnormal activity of mitochondrial respiratory chain 0.5192567217604472 2.43319788212143 0.0149661192328358 1.0 0.1505965747804108 57 Q96CU9,Q9Y2R0,O43676,Q9Y6M9,O96000,Q9P0J0,Q8TB37,Q86Y39,Q70HW3,Q8N183,Q9UBX3,P21912,P13073,P03886,O75380,Q9Y375,Q9NPL8,P51970 18 +Parkinsonism 0.5810803184523361 2.429600054435834 0.0151154922049281 1.0 0.1514468521562435 30 Q9NZJ7,P07602,P04062,O96008,P35637,Q99720,Q96RL7 7 +Biliary tract abnormality 0.5948631353520264 2.425526732254935 0.0152861899162086 1.0 0.1521774428971818 28 P09601,Q9NZJ7,Q14108,Q10713,P07602,P04062,Q14739,P02545,Q5XKP0 9 +Polyneuropathy 0.646646223253474 2.4145405257859247 0.0157550702085405 1.0 0.1549617616988813 21 Q9NZJ7,P07602,Q15041,Q9HC21,P03886 5 +Increased bone mineral density 0.6191617517391053 2.4143107340974828 0.0157650110959453 1.0 0.1549617616988813 24 Q14108,Q13126,P04062,Q14739,Q15392,P02545,P54802 7 +Arthritis 0.5312796568623308 2.410746012325488 0.0159199306396453 1.0 0.1561557902447567 44 Q14108,P21964,P01889,O75844,P04062,P35670,P10321,Q14739,P02545,Q13510,Q96RL7 11 +Nasogastric tube feeding in infancy 0.8116345909585164 2.409417890626377 0.0159779909591204 1.0 0.1563967291155835 9 Q9NZJ7,P07602 2 +Cherry red spot of the macula 0.8077883314578903 2.391878966356406 0.0167623690719704 1.0 0.1617014487541946 9 Q9NZJ7,P10619,P07602,P17900,Q13510 5 +Poor head control 0.4659501833015775 2.3892488676435453 0.0168828617205611 1.0 0.1625280028315468 82 Q9NZJ7,Q10713,P53007,P13073,Q96CU9,O43676,Q9NWM8,Q9Y6M9,Q8N183,P21912,P00374,Q5XKP0,P51970,O96000,Q86Y39,P03886,O75380,P07602,Q96T60,Q9P0J0,Q8TB37,P17900,P02545,Q9Y375,Q9NPL8 25 +Neck muscle weakness 0.6981736240059595 2.3870599171115043 0.0169837230284839 1.0 0.1629455192577751 16 Q9NZJ7,P07602,P35637,Q99720,P02545,Q9BTV4 6 +Young adult onset 0.7401214867334406 2.386793587903055 0.0169960308157071 1.0 0.1629455192577751 13 O15118,Q9NZJ7,P07602,P38435 4 +Mania 0.7221096530054292 2.384487768411831 0.0171029165525482 1.0 0.1632996265518359 14 P21964,P16615,P51812,P03886,P12235,P00403 6 +Delusions 0.6399199545773767 2.372922220540372 0.0176479797958639 1.0 0.1678175512563927 21 Q9BQE5,Q9NZJ7,P21964,P07602,O43681,P04062,Q96RL7 7 +Hypocholesterolemia 0.8347100956722522 2.3604092740262983 0.0182547829180945 1.0 0.1725335656772946 8 Q9NZJ7,P07602,Q9NVI7,Q15800,P37268 5 +Ventricular arrhythmia 0.529023247190123 2.3533735718318587 0.0186039331282954 1.0 0.1751245237419585 39 P50402,P49748,P42892,P09493,P13473,O43772,P23786,P21912,P03886,P02545,P12235,Q9BTV4,P00403 13 +Left ventricular hypertrophy 0.6185495997376759 2.348805183630902 0.0188337580212325 1.0 0.1765759361468569 23 O75880,O00255,Q13724,O75431,P40939,P21912,P03886,P10253,Q6NUK1,P12235,P00403 11 +Lower limb hyperreflexia 0.6504428735693749 2.339313567729595 0.0193192110291207 1.0 0.1796840563644713 19 Q14739,Q15041,P13073 3 +Dental crowding 0.5743705509719769 2.329084120567199 0.0198546097475988 1.0 0.1824826238416126 29 P51812,O75844,Q96A33,Q01105,P02545,Q9UBM7,Q92643 7 +Increased csf lactate 0.5101874644731216 2.317409346865487 0.0204814436690232 1.0 0.1878739891761682 54 Q8NI60,Q9HC21,P13073,Q96CU9,O43676,Q9Y6M9,Q8N183,Q96I36,Q9NWS8,P51970,O96000,P82930,Q86Y39,P03886,O75380,O43819,P00403,Q9P0J0,Q8TB37,Q9Y375,Q9NPL8 21 +Emg neuropathic changes 0.5789247418159377 2.3129612907106876 0.0207247674946986 1.0 0.1893619166981369 28 Q9NZJ7,Q9NR77,P07602,P22626,O43681,O95140,Q8TB36,O14773,Q969X5,O60313,Q13510,Q96RL7 12 +Ankle clonus 0.7404201594918094 2.3027476302335 0.0212930466177583 1.0 0.192431956467682 12 P49589,P07602 2 +Abnormal csf protein level 0.7400418068438089 2.3008564451612012 0.0213997466981206 1.0 0.192431956467682 12 Q9NZJ7,Q9NR77,P07602,O43681,P03886,P00403 6 +Depression 0.4227710827234283 2.294089670976035 0.0217853485438528 1.0 0.1944535605325524 108 Q9NZJ7,P01889,P35670,O76024,P49589,P12235,Q96RL7,P21964,O43681,Q15165,P50897,Q9NZ01,P20700,P04062,Q6DKK2,P03886,P00403,P07602,P51812,Q9Y4P3,O14656,Q96N66 22 +Bone marrow foam cells 0.8654116324810276 2.2933569803799125 0.0218274612246458 1.0 0.1944535605325524 2 O15118 1 +Hepatomegaly 0.3929060387619549 2.2884384518448764 0.0221120005423116 1.0 0.195804502567654 189 Q9UGP8,Q14108,Q9NZJ7,Q10713,P53007,Q9HC21,P28288,Q9NVI7,P35670,Q9H0U3,O15118,Q9BUB7,P16278,P56589,Q01844,P23786,Q96RL7,Q96CU9,Q07021,O43676,Q9Y6M9,Q16134,O95140,P33991,P14927,P04066,O75431,Q8N183,Q96HY6,Q96I36,Q9NWS8,P00374,Q9Y4L1,Q96A33,P40855,P08236,O75880,P09601,O75381,O43772,O96000,P04062,Q86Y39,Q6PGP7,P03886,P10253,Q13510,O75380,Q9BT22,Q9UJS0,P54802,P61916,P49748,Q9Y619,P07602,Q9HC07,Q8TB37,P40939,Q9Y375,Q14739,Q9NX14,P02545,Q13724,P14314,P00813,Q9NPL8 66 +Exercise intolerance 0.5316040549309287 2.2881652707056843 0.0221278983472428 1.0 0.195804502567654 34 Q8NI60,Q07021,Q9Y2R0,P13473,Q9H2D1,Q9Y276,P40939,Q53H12,P23786,P03886,Q9Y285,P12235,P00403 13 +Abnormal pulmonary interstitial morphology 0.5464591940464842 2.282290384503143 0.0224722018611964 1.0 0.1975945583614431 32 P09601,Q14108,Q13432,P04062,Q13510 5 +Central scotoma 0.7681194878128299 2.2807641835715065 0.0225624048495551 1.0 0.1980147899296488 10 Q8NHS3,Q9H061,Q8WWV3,P03886,O60313,Q9Y287 6 +Absent nipple 0.8614779432424813 2.275947456074707 0.0228491546648084 1.0 0.1987911743136764 2 Q6NUK1 1 +Frequent falls 0.518097584335871 2.275238233435233 0.0228916424587632 1.0 0.1987911743136764 41 Q9NZJ7,Q9NR77,P07602,P53007,O43681,P04062,O95140,Q7RTS9,P40939,P21912,Q13510,O43819,P12235 13 +Abnormal posturing 0.861196965439728 2.2747027993863083 0.0229237644537101 1.0 0.1987911743136764 2 O14678 1 +Increased cerebral lipofuscin 0.9527559055118092 2.266948513988564 0.0233933710916829 1.0 0.1988318203828956 5 Q9NZJ7,P50897,P07602,O14773 4 +Finger agnosia 0.8583871874121904 2.2622480439321317 0.023682082487896 1.0 0.1994734597092306 2 O96008 1 +Cerebral amyloid angiopathy 0.8583871874121897 2.2622480439321246 0.0236820824878964 1.0 0.1994734597092306 2 Q9Y287 1 +Vascular tortuosity 0.8583871874121864 2.2622480439321135 0.0236820824878971 1.0 0.1994734597092306 2 P03886 1 +Abnormal mitochondria in muscle tissue 0.5903457697292488 2.26133050018375 0.0237387989041479 1.0 0.1994734597092306 25 O43676,Q9Y6M9,O96000,Q8TB37,Q86Y39,Q8N183,P03886,O75380,Q9Y375,Q9NPL8,P00403 11 +Poor eye contact 0.5137124381868484 2.261085534919316 0.0237539609334616 1.0 0.1994734597092306 44 O43676,P53007,Q9Y6M9,O96000,Q9UHX1,Q9P0J0,Q8TB37,Q86Y39,Q8N183,P03886,O75380,Q5XKP0,Q9Y375,Q9NPL8 14 +Bilateral cryptorchidism 0.7630326440357238 2.256584221887027 0.0240340671917087 1.0 0.2011022575592977 10 O43924,P37268 2 +Splenomegaly 0.43235308703877 2.2545945150462106 0.0241587920543888 1.0 0.2017842577852265 96 Q9NZJ7,Q14108,Q10713,P01889,P35670,O15118,P16278,Q96RL7,P21964,Q96HY6,Q15392,Q96A33,P04062,Q6PGP7,P10253,Q13510,Q9BT22,P54802,P07602,Q14739,P02545,P00813 22 +Extra axial cerebrospinal fluid accumulation 0.8550154537791494 2.2472827293267184 0.0246219639144609 1.0 0.2045550703142669 2 P20700 1 +Episodic respiratory distress 0.8544534981736359 2.244786435674466 0.0247818459709314 1.0 0.2047901572358921 2 P03886 1 +Bruising susceptibility 0.5167587930640359 2.2374930337574868 0.025254134117544 1.0 0.2079568821778011 36 Q8NCH0,Q14108,Q9NWM8,P04062,P35670,P38435 6 +Proximal tubulopathy 0.5745136880243206 2.235905146798316 0.025357985110584 1.0 0.2084444233826003 27 O43676,Q9Y6M9,O96000,Q8TB37,Q16134,Q86Y39,Q8N183,P03886,O75380,Q9Y375,Q9NPL8,P00403 12 +Cerebral inclusion bodies 0.6694630027868638 2.2275782955447303 0.0259086493488307 1.0 0.2118467218205148 16 P61916,P04062,O96008,O15118,P05067,Q9Y287 6 +Hepatic failure 0.5041200390973644 2.2269086646465066 0.0259533786423933 1.0 0.2118467218205148 50 Q10713,O75381,P01889,P28288,P08574,O43772,P04062,P35670,Q6PGP7,O15118,P40939,P03886,P56589,P22830,Q13510,P23786,P40855 17 +Abnormal vascular physiology 0.4986152614417488 2.2222874702094284 0.0262638843760498 1.0 0.2130081070376439 55 P00403,Q14108,Q9NWM8,P01889,O96000,P04062,O75844,Q9Y4P3,P03886,Q14739,P02545,Q6NUK1,Q8IZA0,P51970 14 +Hyperactive patellar reflex 0.8035757986739926 2.2222235638957284 0.0262682007557517 1.0 0.2130081070376439 8 Q15041,P13073 2 +Scotoma 0.7078265680319662 2.220750892821099 0.0263678383293639 1.0 0.2130081070376439 13 Q8NHS3,Q9H061,Q8WWV3,P03886,O60313,Q9Y287 6 +Cns demyelination 0.6911882990914767 2.2207279842413077 0.0263693908476672 1.0 0.2130081070376439 14 Q9NZJ7,P07602,P51648 3 +Optic disc pallor 0.4946460546678289 2.2186536301492668 0.0265102979486444 1.0 0.2132809503816488 58 Q10713,Q9H061,Q96S66,Q96CU9,O43676,Q9UG56,Q9Y6M9,Q8N183,Q6P4Q7,O96000,Q86Y39,P03886,O75380,Q8NHS3,Q8TB37,O14656,Q8WWV3,O60313,Q9Y375,Q9NPL8,Q9Y287 21 +Abnormal pupillary function 0.8026799499193487 2.218214534134656 0.026540208218406 1.0 0.2132809503816488 8 Q9NR77,P07602 2 +Abnormality of hepatobiliary system physiology 0.4492554324703688 2.206080880801274 0.0273783371377336 1.0 0.2181390035769254 82 Q10713,P28288,P01889,P35670,O15118,P56589,P22830,P23786,Q8N511,P08574,Q9NWS8,Q5XKP0,Q96A33,P40855,O75381,O43772,P04062,Q6PGP7,P03886,Q13510,Q9BT22,O43819,Q9Y619,P22695,P40939 25 +Bilateral tonic clonic seizure 0.4320320519123447 2.204005815104205 0.0275239351306149 1.0 0.2189254738072248 92 Q9NZJ7,Q9HC21,Q01105,Q5H8A4,Q96RL7,O60508,P22466,Q9NQZ5,P04062,P03886,O43292,Q13510,P00403,P49748,P07602,P51812,Q9Y320,P27544,Q14739 19 +Joint hemorrhage 0.8449002528800145 2.2022592358990125 0.0276470019049406 1.0 0.2195303603642309 2 P38435 1 +Shuffling gait 0.7347975994628313 2.1952139749732034 0.0281482522706244 1.0 0.2220003206951783 11 O75844,P04062 2 +Hallucinations 0.5008824179427527 2.190515759099509 0.0284868531619182 1.0 0.2242919349291673 49 Q9BQE5,Q9NZJ7,P21964,P07602,O75503,O43681,Q6DKK2,O96008,P04062,O76024,P35637,P50897,O60313,P05067,Q9UJS0 15 +Increased serum lactate 0.4139106350683221 2.1807874406523227 0.029199141944205 1.0 0.2287429425125726 107 Q8NI60,Q86VD7,Q9NVI7,Q9BUB7,Q53H12,P13073,P12235,Q6P4A7,O14949,Q96CU9,Q9Y6M9,P08574,Q70HW3,Q8N183,Q96I36,P21912,Q9NWS8,Q5XKP0,P51970,O75880,P82930,Q86Y39,Q9BWD1,P03886,P00403,P22695,Q9P0J0,Q9H078,Q9UBX3,Q9Y375 30 +Abnormal atrioventricular conduction 0.6993699577704943 2.1767290384289546 0.0295007903499424 1.0 0.2303069139981927 13 P50402,O43772,P21912,P02545,Q9BTV4 5 +Abnormal aortic valve morphology 0.501789363343999 2.175454277282045 0.0295960908971761 1.0 0.2303069139981927 46 P21964,P51812,P01889,O75844,Q9UHX1,P04062,Q6PGP7,Q9Y4P3,Q9BUB7,P02545,P37268 11 +Bilateral tonic clonic seizure with focal onset 0.95718897000882 2.1674213988634583 0.0302027370607063 1.0 0.2327006259677191 4 P22466,P07602 2 +Psychosis 0.523798412304682 2.163598182123358 0.0304952011810974 1.0 0.2345668769597104 33 P61916,Q9Y287,P51812,Q6DKK2,O76024,O15118,P03886,Q9UJS0,Q96RL7,P00403 10 +Fluctuations in consciousness 0.7894047865429458 2.1585910906037302 0.0308819045684829 1.0 0.2363273739434235 8 O00255,P04062,P03886,Q9UJS0,P00403 5 +Loss of speech 0.6133132875484015 2.1582178449386755 0.0309108986164858 1.0 0.2363273739434235 20 Q9NZJ7,P07602,O43681,O15118,P50897,P17900 6 +Vascular skin abnormality 0.4077659472849538 2.152736622459773 0.0313393835576405 1.0 0.2379245233018271 128 Q14108,P10619,P35670,P16278,Q06136,P22830,Q9UBM7,Q8NCH0,Q9NWM8,P21912,P04062,P03886,P51648,Q8IZA0,P00403,P51812,Q13126,O75844,Q14739,P02545,P38435 21 +Prenatal maternal abnormality 0.6671500802347408 2.1505175994236403 0.0315142953991061 1.0 0.2387083456847644 15 O43772,Q8TAA9,Q14739,P40939,P16435 5 +Postural tremor 0.6540793545430837 2.1408758311109892 0.032284052657338 1.0 0.2414385770483063 16 Q9NR77,Q14108,P03886 3 +Increased serum pyruvate 0.5042837404903515 2.1378956419361734 0.0325252140443945 1.0 0.2415063141843506 37 O43676,Q9Y6M9,O96000,Q8TB37,P22695,Q86Y39,Q70HW3,Q8N183,Q9BWD1,P21912,P03886,O75380,Q9Y375,Q9NPL8 14 +Reduced brain n acetyl aspartate level by mrs 0.943333858192438 2.1373619504840713 0.0325685636723755 1.0 0.2415063141843506 3 P07602 1 +Abnormal brain n acetyl aspartate level by mrs 0.943333858192438 2.1373619504840713 0.0325685636723755 1.0 0.2415063141843506 3 P07602 1 +Abnormal brain choline level by mrs 0.943333858192438 2.1373619504840713 0.0325685636723755 1.0 0.2415063141843506 3 P07602 1 +Abnormal macular morphology 0.5600501082552305 2.1333089890003003 0.0328993873121346 1.0 0.2430494293676526 27 P04062,P50897,P51648,Q13510,Q9UM00 5 +Abnormality of the glenoid fossa 0.8283225625175555 2.128062512335844 0.033331900942799 1.0 0.2450813314991002 2 Q7RTS9 1 +Abnormal metabolic brain imaging by mrs 0.6511940040186625 2.1245165460465936 0.033626973974568 1.0 0.246088309541157 16 Q9NZJ7,P03886,P07602,P21912 4 +Focal t2 hyperintense brainstem lesion 0.5921969609182569 2.1217511135743625 0.0338586438590509 1.0 0.2470093877779823 22 Q96CU9,O43676,Q9Y6M9,O96000,Q8TB37,Q86Y39,Q8N183,P03886,O75380,Q9Y375,Q9NPL8 11 +Abnormal brainstem mri signal intensity 0.5696679268215746 2.11944092393319 0.0340532213672652 1.0 0.2480413269325455 25 Q96CU9,O43676,Q9Y6M9,O96000,Q8TB37,Q86Y39,Q8N183,P03886,O75380,Q9Y375,Q9NPL8 11 +Focal segmental glomerulosclerosis 0.5992999847405482 2.1171538534458505 0.0342467923939964 1.0 0.2490627316005751 21 O95470,Q14108,P03886 3 +Ovotestis 0.8235459398707448 2.106591231993149 0.0351530274204401 1.0 0.2536777202875347 2 P53701 1 +Pedal edema 0.7460057211178854 2.1050414322746205 0.0352877016525086 1.0 0.2542566034190782 9 Q14108 1 +Hypothermia 0.7312398646288055 2.1038986423442148 0.0353872894482085 1.0 0.2545812857221661 10 Q5XKP0,P49748,P03886,O43772 4 +Disproportionate short stature 0.5726541003263125 2.102617104367237 0.0354992535411187 1.0 0.2549938688976666 24 Q7LGA3,Q9UHX1,Q7RTS9,Q14739,O00116,Q15392,Q9UBM7,P16278 8 +Abnormal placenta morphology 0.7451228903028786 2.100872965693054 0.0356521191406167 1.0 0.2551790276732981 9 O75844,P16278,P02545 3 +Abnormal lower motor neuron morphology 0.7765388038825972 2.100421140608312 0.0356918109470651 1.0 0.2551790276732981 8 Q99720 1 +Ragged red muscle fibers 0.6233541308880788 2.0998317275295064 0.0357436461979732 1.0 0.2551790276732981 18 Q70HW3,Q9H2D1,P03886,P00403 4 +Personality changes 0.634400919775371 2.0945657533263597 0.0362096122289932 1.0 0.2575928720178463 17 P04062,P35670,P03886,Q96RL7,P00403 5 +Dilated cardiomyopathy 0.4921330722542367 2.0902470681380145 0.0365956114144085 1.0 0.258773616776626 46 P42167,P49748,P13473,P40939,P23786,P03886,P16278,P53701,P02545,P12235,Q9BTV4,Q96RL7,P00403 13 +Aortic valve calcification 0.931141090500282 2.089598250274032 0.0366539038527269 1.0 0.258773616776626 3 O75844,P04062 2 +Photophobia 0.4962386451196919 2.089190917945342 0.0366905406524151 1.0 0.258773616776626 41 Q9NZJ7,Q9Y287,P07602,Q13432,P01889,Q8WWV3,Q96S66,Q6P4Q7,P51648,P40939,P48449 11 +Branchial cyst 0.8182073616184226 2.0825457098163143 0.0372926522421264 1.0 0.2626235193340697 2 Q9UHX1 1 +Abnormality of extrapyramidal motor function 0.4566396734157232 2.0774696331184943 0.0377582351568479 1.0 0.265102556311764 73 Q9NZJ7,P07602,Q6DKK2,P04062,Q9H078,O96008,Q9Y4P3,P35637,P17900,P16278,Q96IX5,P12235,Q99720,Q96RL7,O14949 15 +Delayed puberty 0.4831671381593438 2.0700504423990074 0.0384476210095394 1.0 0.2683352831551537 54 Q14108,O75844,Q9NVI7,P04062,Q15800,P49589,P02545,P16435 8 +Abnormality of skull ossification 0.6632546339670602 2.070040465155895 0.0384485552432636 1.0 0.2683352831551537 14 Q9HC21,O75844,Q14739,P02545,P54802 5 +Hypoketotic hypoglycemia 0.7681046756672208 2.0620843496629613 0.0391997060871129 1.0 0.2720683414584267 8 P40939,O43772,P23786 3 +Incoordination 0.4493038340744885 2.061907606043843 0.0392165332622662 1.0 0.2720683414584267 76 Q9NZJ7,Q10713,P53007,P27635,P35670,Q01105,P49589,P12235,O75503,O43681,O95140,P21912,Q6DKK2,P04062,Q7RTS9,Q13510,O43819,Q9NR77,Q9Y619,P07602,O14773,P40939 22 +Hypokinesia 0.6767201126889463 2.057711983845673 0.0396177893142175 1.0 0.2728728526493624 13 P13473,P04062,Q2TAA5 3 +Abnormal social behavior 0.4508998432628702 2.0576398851342628 0.0396247149488686 1.0 0.2728728526493624 75 Q9NZJ7,P53007,Q9UHX1,O60508,Q96CU9,O43676,Q9Y6M9,O43681,O96008,Q8N183,Q5XKP0,Q2TAA5,O96000,Q86Y39,P03886,O75380,P07602,Q9P0J0,Q8TB37,Q9Y4P3,P05067,Q9Y375,Q9NPL8 23 +Fetal distress 0.5429344385041027 2.053289592716598 0.040044499618371 1.0 0.2753575386129228 28 Q96CU9,O43676,Q9Y6M9,O96000,Q9NVI7,Q8TB37,P49711,Q8N183,Q86Y39,P03886,O75380,Q9Y375,Q9NPL8 13 +Pathologic fracture 0.6148422624925709 2.0486739912044714 0.0404940040959487 1.0 0.2780389781235067 18 Q14108,P04062,P35670 3 +Abnormal auditory evoked potentials 0.7333614919362549 2.04515274487929 0.0408398016164091 1.0 0.2800015179838679 9 Q9NZJ7,P20700,P07602,O60313,Q13724 5 +Enlarged ovaries 0.9192336218394898 2.0427492628316353 0.0410772654606712 1.0 0.2812166458004018 3 P21912 1 +Short middle phalanx of finger 0.8089350941275538 2.0406631447557753 0.0412843210590743 1.0 0.2822203441066149 2 Q9UHX1 1 +Corneal opacity 0.4766735071761339 2.0384779242842463 0.0415021602856984 1.0 0.2823244882180422 57 P10619,Q9NVI7,P35670,P16278,Q6NUK1,P56589,Q06136,Q9UBM7,Q5H8A4,O95202,P40855,O75381,P04062,P51648,Q13510,O43505,O75844,Q9Y4P3,P53701,P02545 20 +Abnormal pupillary light reflex 0.9236654558078254 2.0380850583975016 0.0415414271590908 1.0 0.2823244882180422 4 Q9NR77,P07602 2 +Slow pupillary light response 0.9236654558078254 2.0380850583975016 0.0415414271590908 1.0 0.2823244882180422 4 Q9NR77,P07602 2 +Stroke like episode 0.8938829573132407 2.035895255205436 0.0417608743859503 1.0 0.2834033757383751 5 O76024,P03886,P00403 3 +Orthostatic hypotension due to autonomic dysfunction 0.7149452792951998 2.0246039431497795 0.0429080490429265 1.0 0.2887359404768868 10 Q9NZJ7,O43681,P04062,P07602 4 +Motor neuron atrophy 0.5846925031404555 2.0233002770832074 0.0430421983511843 1.0 0.2887359404768868 21 Q15165,Q99720 2 +Abnormality of the biliary system 0.3998676357161708 2.022997497881984 0.0430734054869701 1.0 0.2887359404768868 121 Q9NZJ7,Q14108,Q10713,P28288,P35670,O15118,P56589,P22830,Q9UBM7,Q5H8A4,P21964,O43681,Q16134,P49711,O95202,P00374,Q5XKP0,Q96A33,P09601,O75381,P04062,Q6PGP7,Q13510,Q9UJS0,P61916,P49748,P07602,Q9Y4P3,Q14739,P02545,P40939 31 +Dermal atrophy 0.5262062726926505 2.0215108953812706 0.0432269056314722 1.0 0.2887359404768868 30 Q8NCH0,Q9NWM8,O75844,Q15392,P02545 5 +Rhizomelia 0.6984753854366572 2.0145141720978224 0.0439555784605489 1.0 0.2927654719433712 11 Q9UBM7,Q14739,O00116,Q15392 4 +Respiratory distress 0.4737262812590846 2.0105311502209986 0.0443750027403315 1.0 0.2948218934465825 57 Q9NZJ7,P53007,Q9UHX1,P51571,P23786,Q16134,P51970,P04062,P03886,P10253,Q969X5,Q13510,O43819,P49748,Q9Y619,P07602,Q8TCJ2,P53701,Q9NX14 19 +Hip osteoarthritis 0.8021916268614713 2.010109595516317 0.044419590716223 1.0 0.2948218934465825 2 P01889 1 +Low frustration tolerance 0.7257939167209835 2.009118407499847 0.044524577953658 1.0 0.2948218934465825 9 P04062 1 +Nyctalopia 0.4969798202565021 2.0078247668600953 0.0446619160200953 1.0 0.2948218934465825 34 Q10713,O75381,Q13432,O95140,Q96S66,Q6P4Q7,P56589,P38435,P40939,P40855,Q9Y287 11 +Abnormality of coordination 0.3637974946204944 2.0071143472961026 0.0447374888956977 1.0 0.2948218934465825 340 O43924,Q14108,Q03252,P53007,P49589,P56589,Q99720,O14949,Q969G3,Q96CU9,O43676,P12694,P50897,P04062,Q86Y39,P03886,Q13510,Q9NR77,P07602,O14773,P40939,O95470,Q9NZJ7,Q86VD7,P35670,O15118,Q01105,Q5H8A4,Q9Y6M9,O75503,P21912,P00374,Q5XKP0,Q9NQZ5,O43292,P00403,Q9P0J0,Q92643,Q8IV08,Q9Y287,Q10713,Q9NVI7,O76024,Q9BUB7,P16278,Q6P4A7,Q96RL7,O96008,O95202,O15121,Q2TAA5,O96000,Q7RTS9,Q8NHS3,Q9Y4P3,O60313,Q96IX5,Q9Y375,Q9NPL8,Q8NI60,P55795,P01889,P12235,O43681,Q8N183,Q92581,P20700,O75381,Q6DKK2,O75380,P61916,P41440,Q96T60,Q8TB37,P35637,Q8WWV3,P05067 77 +Abnormality of femur morphology 0.4478806940869285 2.005038624509398 0.0449589179982794 1.0 0.2948218934465825 74 Q9NZJ7,P07602,P51812,P02545,Q7LGA3,O75844,Q9UHX1,O75431,P04062,Q7RTS9,Q14739,O00116,P16278,Q96A33,P16435 15 +Limb ataxia 0.573866885499728 2.001418397073862 0.0453473197279714 1.0 0.2948759936674093 22 Q9NR77,Q14108,P04062,O14773,Q8IV08 5 +Resting tremor 0.6066476977196897 1.9991428187147071 0.0455929033632866 1.0 0.2952472479933226 18 Q9NZJ7,P04062,P07602,Q96RL7 4 +Large placenta 0.906408094435077 1.9920686149506568 0.0463635299645015 1.0 0.2994070835466912 3 O75844,P02545 2 +Eeg with focal spikes 0.8582595440414087 1.9852289712004991 0.047119002419329 1.0 0.3018731156431005 6 Q5H8A4 1 +Abnormal response to endocrine stimulation test 0.9043823481916036 1.984043321139529 0.0472510107432972 1.0 0.3021787484849654 3 P16435 1 +Neuronal loss in central nervous system 0.6627517263412068 1.9835100349177088 0.0473104872868943 1.0 0.3021787484849654 13 Q9NZJ7,P07602,P04062,P35637,O15118,Q92581 6 +Abnormal csf metabolite level 0.4673540923217509 1.9824862373205117 0.0474248462269093 1.0 0.3024524345426138 60 Q8NI60,Q9HC21,P13073,Q96CU9,O43676,Q9Y6M9,Q8N183,Q96I36,Q9NWS8,P51970,O96000,P82930,Q86Y39,P03886,O75380,O43819,P00403,Q9P0J0,Q8TB37,Q9Y375,Q9NPL8 21 +Temperature instability 0.7062425067861864 1.9819673544471643 0.0474828945212542 1.0 0.3024524345426138 10 Q9HC21,Q9NZJ7,P07602,Q2TAA5 4 +Parkinsonism with favorable response to dopaminergic medication 0.7050534966278114 1.9761267965984035 0.0481404181644233 1.0 0.305806275387337 10 P04062,P07602 2 +Erlenmeyer flask deformity of the femurs 0.907600961207386 1.9755425829235544 0.0482066071538018 1.0 0.3058106641319306 4 P04062,P07602 2 +Muscle fiber atrophy 0.569702510792956 1.9738537197745176 0.048398378448035 1.0 0.3064852074964125 22 P50402,P53007,P35637,P02545,Q9BTV4,P23786,Q99720,Q96RL7 8 +Horizontal nystagmus 0.5430839401998161 1.9712191706056152 0.0486988120654747 1.0 0.3069145263959084 26 Q9NZJ7,P20700,P07602,P04062,Q9H061,Q8TAD8,O14773,O60313 8 +Ketotic hypoglycemia 0.7934813149761073 1.970530615430058 0.0487775897870779 1.0 0.3069145263959084 2 Q13423 1 +Emg chronic denervation signs 0.634869182509755 1.9704657360989355 0.0487850181553251 1.0 0.3069145263959084 15 Q9NZJ7,P07602,P22626,O43681,O95140,Q969X5,O60313,Q13510 8 +Gastric ulcer 0.9008356232658232 1.969979180192352 0.0488407567171043 1.0 0.3069145263959084 3 P04062 1 +Increased endomysial connective tissue 0.793200337173356 1.9692517681417847 0.0489241868251404 1.0 0.3070255756540063 2 Q5JTV8 1 +Abnormal heart rate variability 0.9052098690662278 1.9662031349261428 0.0492751505046464 1.0 0.3083990317777405 4 P07602 1 +Progressive psychomotor deterioration 0.7165156950263483 1.9647448652191968 0.0494437743990912 1.0 0.3090401374422447 9 Q9NZJ7,Q10713,P07602,P21912,P16278 5 +Progressive spasticity 0.6110614498180101 1.9571849173488065 0.0503257314365888 1.0 0.3132944534365775 17 Q9NZJ7,P07602,P51812,P17900,O60313,O15121 6 +Abnormal ldl cholesterol concentration 0.6424573630914541 1.956158091608421 0.0504465336490769 1.0 0.3136283163882026 14 Q8N511,P50402,Q15800,P02545,P37268,Q9UJS0,Q9BTV4 7 +Abnormality of lipoprotein cholesterol concentration 0.6318905108074032 1.9536683558587105 0.0507404509326012 1.0 0.3150361242078661 15 Q8N511,P50402,Q15800,P02545,P37268,Q9UJS0,Q9BTV4 7 +Lactic acidosis 0.4070518263945043 1.947041293948675 0.0515297842134374 1.0 0.3186656456854828 96 Q8NI60,Q10713,Q9HC21,Q86VD7,Q9BUB7,Q53H12,P12235,Q6P4A7,Q96CU9,O43676,Q9Y6M9,P08574,Q70HW3,Q8N183,Q9NWS8,Q5XKP0,P51970,O96000,P82930,Q86Y39,P03886,O75380,Q9UJS0,P00403,Q8TB37,P40939,Q9Y375,Q9NPL8 28 +Exercise induced muscle stiffness 0.7881427367238001 1.9462103483109603 0.051629477372427 1.0 0.3187848230624064 2 P53985 1 +Ichthyosis 0.4814097649363321 1.9446081027296795 0.0518221633549724 1.0 0.3187848230624064 37 P50402,O75381,P04062,Q15800,O95470,P51648,P02545,P56589,Q9BTV4,P40855,P48449 11 +Functional motor deficit 0.3802103777315516 1.9385663512281115 0.0525541641591891 1.0 0.3207669610634459 156 Q9NZJ7,Q8NI60,Q15041,P53007,Q9HC21,P13473,P35670,Q53H12,O75477,P23786,Q99720,Q96RL7,P12235,Q969G3,Q8WVX9,Q9NWM8,O43681,O95140,P21912,Q9Y2R0,P20700,O00255,P04062,Q7RTS9,P03886,O43292,Q13510,O43819,P00403,Q9NR77,P07602,Q9H2D1,Q8TB37,P35637,Q9NX14,P53701,O14773,P40939,P07196 39 +Cachexia 0.5849951413511147 1.9381973243871904 0.0525991530671419 1.0 0.3207669610634459 19 Q9NZJ7,P07602,P04062,P35637,P02545,Q99720,Q92581 7 +Abnormal myocardium morphology 0.3710930222160742 1.937983031148067 0.0526252928195758 1.0 0.3207669610634459 191 Q14108,P13473,P01889,Q9NVI7,Q9H061,O76024,Q9BUB7,Q53H12,P16278,P56589,P23786,P12235,Q96RL7,P50402,Q96CU9,O43676,P09493,Q9Y6M9,Q8N183,Q96I36,P21912,Q9NWS8,Q5XKP0,Q9BTV4,P40855,P08236,O75381,P22626,O43772,O96000,P04062,Q86Y39,P03886,P10253,O75380,Q9BT22,P54802,P00403,P42167,Q13423,P49748,O60313,Q9P0J0,Q8TB37,Q9H078,Q9Y4P3,P53701,P02545,Q96IX5,P40939,Q9Y375,Q9NPL8 52 +Short umbilical cord 0.8922092317621808 1.9357025149544944 0.0529041462700834 1.0 0.3212086592132894 3 O75844 1 +Small placenta 0.8922092317621808 1.9357025149544944 0.0529041462700834 1.0 0.3212086592132894 3 O75844 1 +Irritability 0.4330470789594572 1.929084281736428 0.0537203999934268 1.0 0.3244767756394693 78 Q5BJH7,Q9NZJ7,P07602,Q9HC21,O43772,P49589,P50897,Q13510,P37268 9 +Abnormal pr interval 0.7839280696824886 1.926977433032507 0.0539824423773134 1.0 0.3252180947866912 2 P10253 1 +First degree atrioventricular block 0.7839280696824852 1.9269774330324905 0.0539824423773154 1.0 0.3252180947866912 2 P02545 1 +Distal peripheral sensory neuropathy 0.8652241838527345 1.9214749706493677 0.0546718548844564 1.0 0.328947023782896 5 P40939,P03886 2 +Aspiration pneumonia 0.530528543993686 1.9201719796958825 0.0548361797014553 1.0 0.3290125428320064 27 O14908,Q969G3,P20700,P04062,Q8TAQ2,P16278,Q6NUK1,Q13510 8 +Abnormal epiphyseal ossification 0.5936101377577033 1.919774033675394 0.0548864481121114 1.0 0.3290125428320064 18 Q9UG56,O75381,P40855,Q7RTS9,Q96HY6,Q14739,O00116,P56589,Q9UBM7,P38435 10 +Nephropathy 0.553824512083782 1.918400605906131 0.0550602342938637 1.0 0.3291629115467988 23 Q14108,Q10713,P03886,P00403 4 +Recurrent aspiration pneumonia 0.7885170846891218 1.9172825546871135 0.0552020449966126 1.0 0.3295886804209519 7 Q13510,P04062 2 +Ectrodactyly 0.5750531507367885 1.916358330725053 0.0553195008871238 1.0 0.3298681349195165 20 Q9NR77,Q8TB36,O95202,Q5H8A4,Q9UBM7,Q99720,P48449 7 +Muscle stiffness 0.5922227776554952 1.9112875843958943 0.055967633700543 1.0 0.3318757817229342 18 Q9NZJ7,P23786,P07602,Q15392 4 +Concentric hypertrophic cardiomyopathy 0.8854796019748655 1.9088951204455744 0.0562756226325014 1.0 0.332465502138619 3 P03886 1 +Left ventricular systolic dysfunction 0.8392967264705858 1.9079315129792165 0.0564000686559105 1.0 0.332465502138619 6 P49748,O75844,P02545 3 +Abnormality of lysosomal metabolism 0.8614494550343478 1.906313311107754 0.056609568258771 1.0 0.332465502138619 5 Q13510,P07602 2 +Decreased activity of mitochondrial complex iv 0.6128855851601397 1.9044112732189535 0.0568566421570195 1.0 0.333491270063395 16 Q70HW3,Q9Y2R0 2 +Undetectable electroretinogram 0.8607928901379177 1.9036740209043448 0.0569526519016714 1.0 0.333491270063395 5 O43924,P50897 2 +Glomerular sclerosis 0.4843436252500646 1.9033222604114204 0.0569985079268771 1.0 0.333491270063395 34 O95470,Q14108,P03886,P21912 4 +Respiratory arrest 0.7035296819227491 1.902284008261359 0.057134035191418 1.0 0.3338658451924039 9 P49748,P13473,P23786,O43772 4 +Peripheral demyelination 0.578857052839669 1.899628607037014 0.0574818753347443 1.0 0.3345582528499339 19 Q9NZJ7,Q9NR77,P07602,O43681,Q8TB36,P03886 6 +Generalized amyotrophy 0.5275493922495382 1.89838591289554 0.0576452639530846 1.0 0.3345582528499339 27 Q03252,P54886,P22626,P13473,Q8IY17,Q9BQP7,Q9UGM6,P35637,P49589,P02545,O43819 11 +Abnormal head movements 0.6754342643055682 1.897986541262628 0.0576978549835915 1.0 0.3345582528499339 11 P20700,Q99720,Q96RL7 3 +Generalized onset seizure 0.391632128379647 1.8957530179684905 0.057992711035365 1.0 0.3355241236977937 111 P05023,Q9NZJ7,Q14108,P07602,P51812,Q8NHS3,P04062,O75503,Q9NVI7,Q01105,Q9NZ01,P03886,P21912,P00374,Q13510,O43292,Q96N66,P16278 18 +Recurrent pancreatitis 0.8813105268005444 1.892258552372325 0.0584565404038976 1.0 0.3375003647451701 3 P03886 1 +Dysphagia 0.3843416903443449 1.892090983010053 0.0584788595157084 1.0 0.3375003647451701 141 Q9NZJ7,Q14108,P01889,Q9UHX1,P35670,O15118,Q01105,O76024,P12235,Q99720,Q96RL7,Q12959,Q8N183,P21912,Q92581,P20700,P04062,P03886,Q13510,Q8IZA0,P61916,Q9NR77,P07602,P35637,Q14739,O60313,P05067 27 +Stillbirth 0.6739962476812287 1.8906658900690656 0.058668958514487 1.0 0.3375692354739328 11 O75844,P04062,Q14739,P16435 4 +Abnormality of the larynx 0.4688943907019808 1.890005386491323 0.0587572396833868 1.0 0.3375692354739328 47 Q9NZJ7,P21964,P07602,Q9UHX1,P35637,Q8TAD8,Q96HY6,Q15165,Q14739,P02545,Q13510,Q9UBM7,P16435 13 +Abnormal urine protein level 0.4564891708302716 1.8881137898954403 0.0590106759753257 1.0 0.3375692354739328 61 P09601,Q14108,P04062,P35670,P21912,P03886,O95470 7 +Photoreceptor layer loss on macular oct 0.7752177577971255 1.8871400300205912 0.0591414938140237 1.0 0.3375692354739328 2 Q96S66 1 +Abnormal optical coherence tomography 0.7752177577971255 1.8871400300205912 0.0591414938140237 1.0 0.3375692354739328 2 Q96S66 1 +Juvenile onset 0.4714812060624235 1.8845462413397127 0.0594911261363779 1.0 0.3391502660937103 43 P50402,P41440,Q9NR77,P22466,Q03252,P07196,Q8NHS3,Q8IY17,Q9H0U3,O15118,O14773,P16278,Q13510,P02545,P54802 15 +Abnormality of the temporomandibular joint 0.8830967183908234 1.8794674017739612 0.0601807005557069 1.0 0.3405862919934491 4 O75844,P02545 2 +Hyperactive deep tendon reflexes 0.7793501174768133 1.8774008751596527 0.0604631716442181 1.0 0.3413573741316255 7 Q9NR77 1 +Optic neuropathy 0.5298085781808803 1.875866375955722 0.0606736307511222 1.0 0.3415215905588669 26 O43676,Q9Y6M9,O96000,Q9P0J0,Q8TB37,Q86Y39,Q8N183,P03886,O75380,Q9Y375,Q9NPL8 11 +Generalized myoclonic seizure 0.4704889834001981 1.875715961955268 0.060694292908688 1.0 0.3415215905588669 43 Q9NZJ7,P07602,P04062,Q01105,P21912,P03886,P16278,Q13510,Q96N66 9 +Brittle hair 0.6180794919293421 1.8753850686978144 0.0607397677679431 1.0 0.3415215905588669 15 O75844,Q9NVI7,P49589,Q6PGP7 4 +Action tremor 0.4605420161608957 1.875057270561506 0.0607848450962558 1.0 0.3415215905588669 56 P41440,Q9NZJ7,Q14108,P20700,Q9NR77,P07602,O43681,O95140,P35637,Q9BUB7,P03886,O14773,Q99720,Q96RL7,Q9Y287 15 +Mitral valve calcification 0.8802361540624054 1.8682003999551628 0.0617341430725451 1.0 0.3437645744857834 4 O75844,P04062,P02545 3 +Cardiac valve calcification 0.8802361540624054 1.8682003999551628 0.0617341430725451 1.0 0.3437645744857834 4 O75844,P04062,P02545 3 +Mutism 0.6057243377542086 1.8626718086504368 0.0625084545366763 1.0 0.3437645744857834 16 P22626,P35637,P53701,Q13510,Q92581 5 +Decreased libido 0.7698791795448119 1.862665495700037 0.0625093432723087 1.0 0.3437645744857834 2 O00255 1 +Galactorrhea 0.7698791795448119 1.862665495700037 0.0625093432723087 1.0 0.3437645744857834 2 O00255 1 +Broad jaw 0.7698791795448101 1.8626654957000277 0.06250934327231 1.0 0.3437645744857834 2 Q8TAD8 1 +Dysmenorrhea 0.769879179544805 1.8626654957000055 0.0625093432723131 1.0 0.3437645744857834 2 P02545 1 +Mucosal telangiectasiae 0.6811949602393328 1.858159764017185 0.0631463299397636 1.0 0.3468590758691253 10 Q8IZA0,Q14739,P21912 3 +Visual loss 0.4583531887042371 1.8540757984464191 0.0637283165765951 1.0 0.3487328003653329 56 Q9NZJ7,P00403,Q10713,P07602,Q8NHS3,O75503,P50897,P03886,P53701,O60313,O14773,P40939,P48449 13 +Gait ataxia 0.4352844199273715 1.851409664943149 0.0641106397018407 1.0 0.3491750632083735 73 P41440,Q9NZJ7,Q14108,Q10713,P20700,Q9NR77,P07602,Q9NVI7,O43681,O15118,O43292,P03886,O14773,P12235,Q5H8A4,Q8IV08,Q92581 17 +Abnormal placental size 0.8757824872431628 1.8506377981985664 0.0642216781148561 1.0 0.3491750632083735 4 O75844,P02545 2 +Dysostosis multiplex 0.6795808666649571 1.85012656712938 0.0642953096382468 1.0 0.3491750632083735 10 P10619,P04066,P16278,P54802,P08236 5 +Paroxysmal involuntary eye movements 0.5436990563135267 1.8491679388393496 0.0644335666916009 1.0 0.3494080405146165 23 O43676,Q9Y6M9,O96000,Q8TB37,Q86Y39,Q8N183,P03886,O75380,Q9Y375,Q9NPL8 10 +Arteriosclerosis 0.6028666038798164 1.84596407580408 0.0648974217656972 1.0 0.3515151533921582 16 O75844,O15118,P02545,Q13510,P38435 5 +Muscle weakness 0.3621279105882753 1.8443089806021915 0.0651381234465398 1.0 0.3520461552913462 313 P53007,Q53H12,P56589,Q99720,Q969G3,Q96CU9,O43676,Q8WVX9,P82663,O95140,Q70HW3,Q15165,P40855,P22626,O43772,O00255,Q86Y39,Q92796,P03886,Q13510,O43819,Q9NR77,P07602,P51812,Q9HC07,Q14739,P40939,Q9NZJ7,Q9HC21,Q9UHX1,P35670,P13073,Q8NCH0,Q9NWM8,Q9Y6M9,P21912,P00374,Q5XKP0,P00403,Q13126,Q9P0J0,P17900,P02545,Q10713,P13473,P23786,Q96RL7,P50402,Q16134,Q8TB36,Q9BTV4,P51970,O96000,Q7RTS9,P05023,P49748,O43505,O60313,Q9Y375,Q9NPL8,Q5JTV8,Q8NI60,P01889,Q6NUK1,P12235,O43681,Q8N183,P20700,O75381,Q6DKK2,Q969X5,P10253,O75380,P41440,Q96T60,Q8TB37,P35637,O15269 78 +Abnormality of circulating leptin level 0.8741649879114899 1.8442531352009128 0.0651462579078439 1.0 0.3520461552913462 4 O75844 1 +Mitral stenosis 0.8738420760367316 1.842978129849734 0.0653322036949741 1.0 0.3522917941584521 4 O75844,P04062 2 +Type 1 muscle fiber atrophy 0.7200264560425638 1.840518821563497 0.065692103592809 1.0 0.3537675105822671 8 P50402,P02545 2 +Abnormality of salivation 0.4650034142862283 1.8393354804397988 0.0658658575054902 1.0 0.3542945722271128 45 Q9NR77,P55795,P51812,P01889,P35670,P35637,Q15165,Q14739,Q96RL7,Q92581 10 +Bone pain 0.5245328931789417 1.8377030559358287 0.0661061733258174 1.0 0.3551780474778386 26 Q9NZJ7,Q14108,P04062,P07602 4 +Abnormality of the gastric mucosa 0.6109715893131014 1.8348421972819948 0.0665290742644428 1.0 0.3566092593481463 15 O76024,P04062,Q14739,Q6PGP7 4 +High frequency sensorineural hearing impairment 0.8436026684266417 1.8343524947463632 0.066601686474959 1.0 0.3566092593481463 5 Q13510,Q9NWM8,O75844 3 +Abnormal muscle fiber morphology 0.4335037262176147 1.8323269272076717 0.0669027276379057 1.0 0.3577790050489021 73 Q5JTV8,Q8NI60,P50402,O43676,P02545,Q9H2D1,O96008,Q70HW3,P35637,P23786,P03886,O60313,P05067,Q9BTV4,P12235,Q99720,Q96RL7,P00403 18 +Abnormal visual fixation 0.7181678022005473 1.8318524274859087 0.0669734098121097 1.0 0.3577790050489021 8 P04062 1 +Sea blue histiocytosis 0.8656548622821825 1.8295918552269572 0.0673109925537795 1.0 0.3591714562669679 3 O15118,P16278 2 +Middle age onset 0.6617876961949477 1.8282909809031052 0.067505892695088 1.0 0.3594731928851264 11 Q9NZJ7,P07602 2 +Hypoplastic vertebral bodies 0.7679999487081399 1.8278087219976713 0.0675782637668607 1.0 0.3594731928851264 7 Q14739,Q8TAA9 2 +Prominent sternum 0.8651768699471949 1.8276738545408808 0.0675985143185138 1.0 0.3594731928851264 3 P16278 1 +Brisk reflexes 0.5404955239682453 1.827158158187101 0.067675992949856 1.0 0.359475780526596 23 Q8NI60,Q10713,P82663,P35637,P49589,Q99720,O60508 7 +Inappropriate antidiuretic hormone secretion 0.7620118010677124 1.8265200007718136 0.0677719713493805 1.0 0.3595765161707472 2 Q13724 1 +Motor deterioration 0.8412592546659923 1.824870231731721 0.0680206143572994 1.0 0.3601853568598692 5 O75503 1 +Abnormal larynx morphology 0.5058893627860757 1.820327430813873 0.0687091564389381 1.0 0.362489323630963 29 Q9NZJ7,P21964,Q15427,P07602,P27635,Q9UHX1,P36543,Q8TAD8,Q96HY6,Q14739,P02545,Q13510,P16435 13 +Laryngomalacia 0.6320436828575758 1.8182661292761464 0.0690234670003022 1.0 0.3633264570737444 13 Q9NZJ7,P07602,P16435,P02545 4 +Abnormality of the upper respiratory tract 0.3856988069309699 1.8155048949828203 0.0694463544057952 1.0 0.3642464865181747 107 Q03519,Q9NZJ7,P27635,Q13432,P01889,Q9UHX1,Q9H0U3,Q8TAQ2,Q8TAD8,Q03518,P16278,Q9UBM7,Q86YV9,Q969G3,P21964,Q15427,P36543,Q96HY6,Q15165,P08236,Q7RTS9,Q13510,P54802,P16435,P07602,P35637,Q14739,P02545,P00813 29 +Coxa valga 0.5528320172819186 1.8151641268194876 0.0694986907652177 1.0 0.3642464865181747 21 O75844,Q96A33,P51812,P02545 4 +Abnormality of corneal stroma 0.6313216966211557 1.8143466364123215 0.0696243758350079 1.0 0.3642464865181747 13 Q13510,P10619,P04062,P16278 4 +Foam cells 0.8658982288445243 1.811571334280127 0.0700524575656129 1.0 0.3658556201049741 4 Q13510,O15118,P16278 3 +Temporal pattern 0.7131701022699477 1.808513474258001 0.0705266216316509 1.0 0.3672963428095936 8 Q9NR77,P04062,O60313 3 +Neurofibrillary tangles 0.815049941054827 1.8082710709296723 0.0705643220176066 1.0 0.3672963428095936 6 P61916,O15118,Q9Y287,O96008 4 +Reduced consciousness confusion 0.3788013759711742 1.8071862115766368 0.0707332500815893 1.0 0.3675778554239501 140 Q9NZJ7,Q9HC21,P01889,P35670,Q9UBM7,P23786,Q5H8A4,P12235,Q969G3,Q96CU9,O43676,Q9Y6M9,P12694,O43681,Q16134,O14678,O96008,Q8N183,Q9NWS8,O00255,O43772,P04062,O96000,Q86Y39,P03886,P61313,O75380,O43819,Q9UJS0,P00403,Q13423,P49748,Q9Y619,P07602,P18077,Q8TB37,Q96IX5,P05067,P40939,Q9Y375,Q9NPL8 41 +Abnormal heart valve morphology 0.4001070367919895 1.800641085100935 0.0717594690758349 1.0 0.3715540166780969 90 P55795,P01889,Q9UHX1,Q9BUB7,P16278,Q6NUK1,P37268,Q5H8A4,Q8NCH0,P21964,O95202,P04062,Q6PGP7,P51812,O75844,Q6ZXV5,Q9Y4P3,P53701,P02545 19 +Abnormal circulating acetylcarnitine concentration 0.8131707361507281 1.800509699578083 0.0717801934126458 1.0 0.3715540166780969 6 O43772,P40939 2 +Abnormal speech prosody 0.7100167470327376 1.7937606687427816 0.0728513771768184 1.0 0.3739227094148671 8 P04062 1 +Abnormal visual electrophysiology 0.4539972495572688 1.7879591275428677 0.0737826022857681 1.0 0.3748541567706763 53 Q8N766,P51798,O43924,Q9NZJ7,P07602,Q8IY17,O75503,O43681,O95140,Q13724,P40939,Q53H12,Q96S66,P50897,O60313,O14773,P12235,Q6UX04 18 +Abnormal peripheral myelination 0.4620681071983423 1.7779962726377 0.075404467067782 1.0 0.3808021861054055 37 Q9NZJ7,Q9NR77,P20700,P07602,O43681,Q8TB36,P03886,P02545,O15269,Q96RL7 10 +Peroneal muscle atrophy 0.8573687224611348 1.7777634609760058 0.0754427119613407 1.0 0.3808021861054055 4 Q9NR77,P02545 2 +Abnormality of head blood vessel 0.5252541336709319 1.7733098620689465 0.076177375775994 1.0 0.38326742187297 24 Q9NZJ7,P10619,P21964,P07602,P03886,P17900,P16278,Q13510 8 +Dry skin 0.4614616811906973 1.7710153849624457 0.0765581433667721 1.0 0.3835387660513825 36 Q2TAA5,P51648,Q06136,P37268,P00813 5 +Progressive external ophthalmoplegia 0.6505351417816048 1.7704512992657413 0.0766519904398863 1.0 0.3835387660513825 11 Q07021,P03886,O60313,P12235,P00403 5 +Loss of subcutaneous adipose tissue in limbs 0.855496204666846 1.7703298836270709 0.0766722026506538 1.0 0.3835387660513825 4 O75844,O75431,P02545 3 +Periventricular white matter hyperintensities 0.6763352702868354 1.7701740583140673 0.0766981494489047 1.0 0.3835387660513825 9 Q9NZJ7,O75503,P07602,P17900 4 +Abnormality of alkaline phosphatase level 0.5390614123683762 1.7684840375108988 0.0769800184360567 1.0 0.3839954124764411 22 P14314,Q8N511,P51798,P22626,Q92643,Q14739,Q96A33,Q9UJS0 8 +Progeroid facial appearance 0.6748734331045853 1.763023614113309 0.0778965070125086 1.0 0.3868650295359441 9 O75844,O75431,P02545 3 +Optic nerve dysplasia 0.7479629109300256 1.7617550017631782 0.078110700487775 1.0 0.3868650295359441 2 O43505 1 +Abnormal circulating carbohydrate concentration 0.4577483256820593 1.761609477563542 0.0781353015318901 1.0 0.3868650295359441 43 O43676,Q9Y6M9,O96000,Q8TB37,P22695,Q86Y39,Q70HW3,Q8N183,Q9BWD1,P21912,P03886,O75380,Q9UJS0,Q9Y375,Q9NPL8 15 +Myoclonic seizure 0.4477747418600057 1.7609039529573305 0.078254660767314 1.0 0.3870455626298614 57 Q9NZJ7,P07602,Q8NHS3,Q96N66,O75503,P04062,Q01105,P21912,O43292,P16278,P03886,Q5XKP0,Q13510 13 +Abnormality of the distal phalanges of the toes 0.8245915688276626 1.7572121294076646 0.0788816585739486 1.0 0.3889107327156984 5 Q7LGA3,O75844,P02545 3 +Generalized hyperkeratosis 0.851731926971838 1.7553739537910644 0.0791953642355522 1.0 0.3896431588874494 4 O75844,P21912 2 +Mixed demyelinating and axonal polyneuropathy 0.8241374697636566 1.755363676827602 0.0791971209647011 1.0 0.3896431588874494 5 P03886,P35670 2 +Amyotrophic lateral sclerosis 0.6058848874873792 1.752464328428212 0.0796939984618594 1.0 0.3899051597565943 14 Q99720 1 +Hypolipoproteinemia 0.7508366947840536 1.7523840916637765 0.079707785035048 1.0 0.3899051597565943 7 Q15800,P37268,Q9UJS0,P02545 4 +Spastic diplegia 0.5077244380439232 1.7521301546676242 0.0797514301922355 1.0 0.3899051597565943 27 P07602,Q99720,P51648 3 +Hand polydactyly 0.4661715964519858 1.750994220067812 0.0799469056307755 1.0 0.390451989947794 34 O43924,Q10713,P21964,Q9UHX1,Q9UM00,Q14739,Q9UBM7,Q5H8A4 8 +Abnormal nervous system electrophysiology 0.361384350446248 1.7498451936863706 0.080145029893571 1.0 0.3905392658221156 204 Q9BQE5,Q9NZJ7,Q14108,P53007,Q8TAD8,P13073,P56589,Q99720,Q5H8A4,P48449,Q8N766,Q96RL7,P21964,O75503,O43681,O95140,Q8TB36,P50897,Q9NZ01,O95202,O15121,Q96A33,P40855,Q92581,Q8N2K0,P20700,Q2TAA5,O75381,Q9NQZ5,O15269,P03886,O43292,P02545,P00403,Q2M389,O60313,Q9NR77,Q9Y619,P07602,Q96T60,Q8NHS3,Q9UBX3,O14773,Q13724,Q96N66,P07196,Q8WWI5 47 +Head titubation 0.7500151957216373 1.7487612363266885 0.0803322999494824 1.0 0.3905392658221156 7 P20700,Q99720,Q96RL7 3 +Depletion of mitochondrial dna in muscle tissue 0.8500010641478434 1.748491533482769 0.0803789503872549 1.0 0.3905392658221156 4 Q9UBX3 1 +Abnormal left ventricle morphology 0.507166857721937 1.7479848734288777 0.0804666467596648 1.0 0.3905392658221156 27 O75880,O00255,Q13724,O75431,P40939,P21912,P03886,P10253,Q6NUK1,P12235,P00403 11 +Widened cerebral subarachnoid space 0.845051088373896 1.7466770864759331 0.0806933671858343 1.0 0.3908271072517223 3 P03886 1 +Toxemia of pregnancy 0.80000251687723 1.7459777348739849 0.0808148208225738 1.0 0.3910097392959558 6 O43772,Q14739 2 +Mottled pigmentation 0.8447021746787693 1.7452688793115607 0.0809380764056546 1.0 0.3912007026273308 3 O75844 1 +Cytochrome c oxidase negative muscle fibers 0.7475931372580408 1.738073192247686 0.082197917835173 1.0 0.3916143656861459 7 Q9Y2R0 1 +Segmental peripheral demyelination remyelination 0.8470106122911246 1.7365925662243238 0.0824591125939235 1.0 0.3924583044862683 4 P03886 1 +Broad palm 0.6693513281390756 1.7359689692240623 0.0825693214827838 1.0 0.3925826496976759 9 Q14739,P51812 2 +Conspicuously happy disposition 0.8421398536199669 1.7349234082722715 0.0827543723635289 1.0 0.3930622223451845 3 P55795 1 +Oromandibular dystonia 0.8185899424770775 1.732760490773108 0.0831382478971392 1.0 0.3944842270647793 5 Q99720,Q96RL7 2 +Abnormal neuron morphology 0.5049496601344354 1.7314843192014575 0.0833654192714519 1.0 0.3951605508410243 27 Q15165,Q99720 2 +Chronic hepatic failure 0.8409937448281357 1.7302936846439056 0.083577817315898 1.0 0.3953645684376172 3 P40939 1 +Decreased cervical spine flexion due to contractures of posterior cervical muscles 0.7455807408059036 1.729185409617458 0.0837759168009308 1.0 0.3956656921037089 7 P50402,P02545 2 +Overtubulated long bones 0.840659349543512 1.7289426281516296 0.0838193636870228 1.0 0.3956656921037089 3 O75844 1 +Airway obstruction 0.5828845550931322 1.7283335421068633 0.0839284427982181 1.0 0.3956656921037089 16 P09601,P21964,O75844,P02545,P16435 5 +Unexplained fevers 0.7956848856433132 1.7280433891716434 0.0839804456788981 1.0 0.3956656921037089 6 Q9HC07,P07602 2 +Heart block 0.5323628227659192 1.7229988370096847 0.0848887353496117 1.0 0.3987379329450072 22 P50402,O43772,P02545,Q9H490,P23786,Q9BTV4 6 +Abnormality of the tarsal bones 0.498324174294027 1.7208023447879637 0.0852866967999239 1.0 0.3997723532782478 28 O75844,Q9UHX1,Q9UPT5,O14656,Q7RTS9,Q969X5,Q14739,P02545,P40939,P16435 10 +Contractures of the joints of the upper limbs 0.4000866716737637 1.7203665967385269 0.0853658248486641 1.0 0.3997723532782478 85 P50402,Q9NR77,P42892,Q9BTV4,Q7LGA3,O75844,O14656,Q9BUB7,Q969X5,Q15392,Q8IZA0,P37268,P02545,P23786,Q99720,P16435 16 +Macrovesicular hepatic steatosis 0.74271628788077 1.7165228760512137 0.0860663846972458 1.0 0.4018439501514407 7 Q5XKP0,P23786,Q9Y375 3 +Low back pain 0.7378477100309004 1.7149614067369106 0.0863523029161537 1.0 0.4023741540075066 2 Q8WVX9 1 +Abnormal sharpey fiber morphology 0.6925534207928578 1.7116920094376502 0.086953441946695 1.0 0.4038559646065084 8 P01889,P02545,P35670 3 +Drowsiness 0.7410388171408653 1.7091011957819595 0.0874322061343724 1.0 0.4041791786548364 7 Q5H8A4 1 +Retinopathy 0.4673579625854089 1.7049698179071424 0.0882000536406455 1.0 0.4073254702751474 33 P01889,Q8NHS3,Q9Y375,Q9Y6B6,O95202,P51648,P40939,Q5H8A4 8 +Impaired social interactions 0.4436812705014165 1.704151639701578 0.0883527612784749 1.0 0.4076275122620547 55 Q2TAA5,O43676,P53007,Q9Y6M9,O96000,Q9UHX1,Q9P0J0,Q8TB37,Q86Y39,Q8N183,P03886,O75380,Q5XKP0,Q9Y375,Q9NPL8 15 +Back pain 0.501145594218635 1.7031111927220537 0.088547261717415 1.0 0.4081215843619059 27 P50402,Q9UGP8,Q969G3,P51798,Q8WVX9,P01889,Q8TAA9,P35670,P02545,Q9BTV4,P14314,P36551 12 +Insidious onset 0.8110019005981737 1.7017802814491292 0.0887965642621027 1.0 0.4084641956056724 5 Q9NR77,P04062 2 +Upper airway obstruction 0.8098631760702465 1.6971249834188358 0.0896730337905638 1.0 0.4104739164393552 5 O75844,P16435,P02545 3 +Myotonia 0.6612141137537952 1.6959777372455986 0.0898900962641706 1.0 0.410992314125626 9 P50402,P02545 2 +Mitochondrial inheritance 0.8364233938440355 1.6943862246927834 0.0901919154165726 1.0 0.410992314125626 4 P03886 1 +Metabolic alkalosis 0.7330710873840853 1.6928203950080265 0.0904896593594803 1.0 0.4112888795447542 2 P01889 1 +Abnormality of the tongue 0.3857944871172468 1.6918721801622636 0.090670347370102 1.0 0.4112888795447542 97 O43924,Q10713,Q03252,P01889,Q8TAD8,P16278,P56589,Q6NUK1,Q9UBM7,Q96RL7,Q969G3,O75431,P21912,Q9NWS8,Q96A33,P40855,P20700,O75381,P10253,Q13510,Q7LGA3,O75844,Q9Y4P3,O60826,P02545,P98175 26 +Axial dystonia 0.8314497439228733 1.6916876160270629 0.0907055508893956 1.0 0.4112888795447542 3 Q99720 1 +Color vision defect 0.5949371491889084 1.6906694442465822 0.0908999532904948 1.0 0.4116006209533866 14 Q13432,Q9H061,Q8WWV3,Q6P4Q7,O60313 5 +Abnormality of the umbilical cord 0.6592936040895365 1.6865179382332194 0.0916960829743467 1.0 0.4140512682855172 9 O75844,P16435,P02545 3 +Microretrognathia 0.5851037047014574 1.6858749282687766 0.0918198919296227 1.0 0.4142097347047423 15 Q8NCH0,Q15427,P53007,Q9UHX1,Q9BUB7 5 +Generalized clonic seizure 0.7350353757728096 1.682502430281342 0.0924714540588031 1.0 0.4167463503866333 7 Q9NZJ7,P07602 2 +Avascular necrosis 0.5262858775114609 1.6815569127219945 0.0926547916597186 1.0 0.4169822957221362 22 P51798,Q14108,Q9Y619,Q8IWS0,P01889,O75844,P04062,P02545 8 +Osteolytic defects of the distal phalanges of the hand 0.8328309450797707 1.6800373071934676 0.0929500572980233 1.0 0.4169822957221362 4 O75844,P02545 2 +Cutaneous photosensitivity 0.487208432404641 1.67660252221843 0.0936202332392974 1.0 0.4186904875424136 29 P37268,Q06136,P22830,Q14108 4 +Hypoparathyroidism 0.5833138281161784 1.6754872670453238 0.0938386672610986 1.0 0.4187212886520645 15 P00403,P40939,P03886,P35670 4 +Disproportionate short limb short stature 0.5378834267302628 1.6751940535815009 0.0938961638934914 1.0 0.4187212886520645 20 Q7RTS9,Q14739,O00116,Q15392,Q9UBM7 5 +Retinal dysplasia 0.656427481502774 1.672385498055199 0.094448329887709 1.0 0.4207817292420929 9 O43924,Q10713,O43505 3 +Abnormal shoulder physiology 0.8254840713651632 1.6675098131103374 0.0954130747818493 1.0 0.4231002517867584 3 O75844 1 +Renal tubular dysfunction 0.4452918209832456 1.6655942028256563 0.0957942665812077 1.0 0.4231002517867584 46 Q96CU9,O43676,P40855,Q9Y6M9,O96000,Q8TB37,Q16134,P35670,Q8N183,Q86Y39,Q9NWS8,P03886,O75380,O43819,Q9Y375,Q9NPL8,P00403 17 +Frontotemporal dementia 0.6426589087889193 1.664628086541544 0.0959869782943887 1.0 0.4231002517867584 10 P35637,P05067,O96008 3 +Subcutaneous hemorrhage 0.4457436790233464 1.6635246842208824 0.0962074539609219 1.0 0.4231002517867584 45 Q8NCH0,Q14108,Q9NWM8,Q13126,P04062,P35670,P38435 7 +Cerebral dysmyelination 0.7307321622174128 1.6634011164293685 0.0962321697966972 1.0 0.4231002517867584 7 P07602 1 +Corpus callosum atrophy 0.580868202420378 1.6612776305924066 0.0966577005250131 1.0 0.4231002517867584 15 Q8N766,P20700,O75503,P51572,O60313,P51970 6 +Episodic vomiting 0.6293679921762703 1.6607730190732743 0.0967590419199975 1.0 0.4231002517867584 11 P49748,Q2TAA5,P22695,P03886,P00403 5 +Abnormality of the alveolar ridges 0.6815495786238293 1.659670341934461 0.096980788896563 1.0 0.4231002517867584 8 O43924,Q15392 2 +Psychomotor deterioration 0.6813295655565339 1.6586278557925465 0.0971908050651557 1.0 0.4231002517867584 8 P50897,P07602 2 +Ascites 0.4901231749462841 1.6584262261605316 0.0972314667069946 1.0 0.4231002517867584 28 Q13510,Q14108,P04062,Q14739 4 +Sensory ataxia 0.7992159386520377 1.65352204992661 0.0982246623175298 1.0 0.4262183534949318 5 Q9NR77 1 +Hip pain 0.7986572999428878 1.6512306224723845 0.098691492470093 1.0 0.4270533626903283 5 O75844,P02545 2 +Oculomotor apraxia 0.503261347163705 1.6482428050123643 0.0993028562269502 1.0 0.4289038258312957 25 O43924,Q10713,Q96T60,P04062,O96008,O43292,O14773 7 +Centrocecal scotoma 0.8194782221945411 1.643135030359928 0.1003549984709126 1.0 0.432248605037538 3 P03886 1 +Slow saccadic eye movements 0.6128115943458354 1.6410871171455654 0.1007793325910124 1.0 0.4328782924263451 12 P04062,Q8IV08 2 +Atrophic scars 0.6770251948233732 1.6382143253233894 0.1013769923220828 1.0 0.4350451995880559 8 Q8NCH0 1 +Hypolipidemia 0.7209890418656846 1.6367005683135605 0.1016930501790307 1.0 0.4352030426243993 2 Q9Y6B6 1 +Hypotriglyceridemia 0.7209890418656846 1.6367005683135605 0.1016930501790307 1.0 0.4352030426243993 2 Q9Y6B6 1 +Saccadic smooth pursuit 0.8220006571305358 1.636698859165563 0.1016934074755235 1.0 0.4352030426243993 4 O14773 1 +Bilateral tonic clonic seizure with generalized onset 0.6242220706190577 1.6339428423562885 0.1022708528025169 1.0 0.4362864210094079 11 Q13510,P04062,Q9Y320 3 +Abnormal macrophage morphology 0.7940725202936818 1.6324113320071163 0.1025928635090323 1.0 0.4362864210094079 5 Q13510,O15118,P16278 3 +Absent brainstem auditory responses 0.8209005377450924 1.6322901084807837 0.102618386008058 1.0 0.4362864210094079 4 Q13724,O60313 2 +Elbow flexion contracture 0.4864159982383265 1.630106585049702 0.1030789722227354 1.0 0.4362864210094079 28 P50402,Q7LGA3,Q969X5,P02545,P37268,P23786,Q9BTV4,P16435 8 +Erythema 0.4961312073351325 1.6296720677943377 0.1031708238666448 1.0 0.4362864210094079 26 P03886,P51648,P53701,Q06136,P22830,P00403 6 +Paralysis 0.4369324848215564 1.624516758192922 0.1042655667559768 1.0 0.4381781558808785 53 P50402,Q9NR77,P20700,Q9HC21,P04062,O95140,P35637,Q8TB36,Q15165,P21912,P10253,P17900,P02545,Q9BTV4 14 +Gingival bleeding 0.5963238291666018 1.6225414554340372 0.1046874642984432 1.0 0.4382405685563619 13 Q14108 1 +Posterior polar cataract 0.8135380275199742 1.6189946027463258 0.1054484243946274 1.0 0.4382405685563619 3 Q9Y287 1 +Hypertriglyceridemia 0.5105020583814673 1.6186833779170815 0.1055154050860542 1.0 0.4382405685563619 23 P50402,O75431,O95470,P02545,P22830,Q9BTV4 6 +Elevated hepatic transaminase 0.3737306133220132 1.617126485773407 0.1058509807725271 1.0 0.4382405685563619 104 Q10713,P28288,P01889,P35670,P23786,P12235,Q96RL7,Q8N511,P08574,O75431,Q9Y6B6,Q5XKP0,P40855,Q2TAA5,O43772,P10253,Q13510,Q9UJS0,P49748,Q9HC07,P22695,Q9H078,Q14739,P40939 24 +Lagopthalmos 0.813027996337879 1.6169204466541347 0.1058954542168926 1.0 0.4382405685563619 3 O75844 1 +Abnormal pericardium morphology 0.5952297797191068 1.6164904300301326 0.105988320838829 1.0 0.4382405685563619 13 P49748,Q14108,P04062,P02545 4 +Ascending tubular aorta aneurysm 0.7687205923501982 1.6154684966678656 0.1062092772549325 1.0 0.4382405685563619 6 O75844,P02545 2 +Hyperextensible skin 0.563632235278432 1.6137077739567534 0.1065908269355375 1.0 0.4384780360898898 16 Q8NCH0,P04062,Q9UHX1 3 +Abnormality of central nervous system electrophysiology 0.3542853532259923 1.6120900960637397 0.1069423355909782 1.0 0.4395367648541173 164 Q9BQE5,Q9NZJ7,Q14108,P53007,Q8TAD8,P13073,P56589,Q5H8A4,P48449,Q8N766,P21964,O75503,P50897,Q9NZ01,O95202,Q96A33,P40855,Q92581,P20700,Q2TAA5,O75381,Q9NQZ5,P03886,O43292,P00403,Q2M389,P07602,Q96T60,Q8NHS3,Q9UBX3,O60313,Q13724,Q96N66,P07196,Q8WWI5 35 +Respiratory insufficiency 0.3517669628914195 1.6110353700409 0.1071720134739089 1.0 0.4400236130716631 195 Q9NZJ7,P53007,P13473,O76024,Q9BUB7,Q53H12,P56589,Q6NUK1,P23786,P12235,P50402,Q96CU9,Q15427,O43676,Q9Y6M9,O95140,Q70HW3,Q8N183,Q15165,Q96I36,Q5XKP0,Q9BTV4,P40855,O75381,O43772,O96000,Q86Y39,Q7RTS9,P03886,Q969X5,P10253,Q13510,O75380,Q9BT22,O43819,P61916,Q9NR77,P49748,Q9Y619,P07602,Q8TB37,Q9H078,O14656,P40939,P35637,Q14739,Q9NX14,P02545,P53701,P14314,Q9Y375,Q9NPL8 52 +Impaired glucose tolerance 0.7887381023046867 1.6104855273277467 0.1072919024742034 1.0 0.4400236130716631 5 P02545 1 +Abnormality of the achilles tendon 0.5630544579154941 1.6102489451495097 0.1073435200875185 1.0 0.4400236130716631 16 P50402,Q15041,O60313,P02545,Q9BTV4 5 +External ophthalmoplegia 0.5278370947237815 1.6090065164671334 0.10761491673418 1.0 0.4403628801331169 20 P03886,P21912,O60313,P12235,P00403 5 +Hyperlipidemia 0.4616288732202743 1.6072264414327484 0.1080047036999904 1.0 0.4415708945492606 32 P50402,O75844,O75431,O95470,P02545,P22830,Q9UJS0,P23786,Q9BTV4 9 +Progressive spastic quadriplegia 0.6429354472184139 1.6056247854760886 0.1083563762673933 1.0 0.4422341964969052 9 Q9NZJ7,P07602,P17900 3 +Abnormality of visual evoked potentials 0.5084178304598362 1.604039563779186 0.1087053320463626 1.0 0.4429049672422275 23 Q8N766,Q9NZJ7,P07602,O43681,O75503,O95140,O60313,Q13724,Q6UX04 9 +Chorea 0.3853734932164609 1.6031562043974383 0.1089001718556601 1.0 0.4429049672422275 88 Q9NZJ7,P07602,Q96T60,Q86VD7,Q9P0J0,O43681,Q9H078,P82930,Q01105,Q9NZ01,P03886,P17900,Q9BWD1,Q5XKP0,Q96N66,Q96IX5,Q99720,Q96RL7 18 +Hemianopia 0.6420292392419004 1.6011272670685626 0.1093487340290568 1.0 0.4435701469866781 9 Q969G3,P03886,P00403 3 +Abnormal larynx physiology 0.591937754087602 1.598263541133605 0.1099843377682192 1.0 0.4453745646485825 13 Q15165 1 +Ventricular escape rhythm 0.7644127470776076 1.5973970833334166 0.1101772222074481 1.0 0.4457690212188696 6 P50402,P02545 2 +Elevated serum acid phosphatase 0.8101760000059334 1.589251746543637 0.1120035680181219 1.0 0.4508143612729408 4 P07602 1 +Glomerulopathy 0.6276289506019453 1.588209447428402 0.112238985510523 1.0 0.4511384327666382 10 P01889,Q14108,P02545 3 +Vacuolated lymphocytes 0.8059318453279003 1.5880398376069025 0.1122773310933462 1.0 0.4511384327666382 3 P16278 1 +Ecchymosis 0.5765105229149552 1.585854420613018 0.112772337293191 1.0 0.452737784025717 14 P04062,P38435 2 +Abnormal thoracic spine morphology 0.47536298832016 1.5844148395114517 0.1130993471549808 1.0 0.4536605256585957 29 O75844,Q9UHX1,P04062,P51648,P02545 5 +Pseudoarthrosis 0.804875767298768 1.5837382226438987 0.1132533028142144 1.0 0.4538881294760233 3 O75844 1 +Equinovarus deformity 0.7112720181305874 1.5766665388895764 0.1148722735369216 1.0 0.4581977763646728 7 Q9NR77,P40939,Q96RL7 3 +Retrocollis 0.8031218897058414 1.5765924084741676 0.1148893406655571 1.0 0.4581977763646728 3 Q99720 1 +Cholestatic liver disease 0.759346450919168 1.5761155717442232 0.1149991710106017 1.0 0.4581977763646728 6 P40939 1 +Abnormal sella turcica morphology 0.6368026954345787 1.5751558560741672 0.1152204737922035 1.0 0.4586226701924965 9 Q7RTS9,O75431,P16278 3 +Thoracic hypoplasia 0.4451662340105825 1.5719821738097923 0.1159546854394442 1.0 0.4596287265013625 34 Q9UHX1,P04062,Q9UM00,P50454,Q96HY6,Q92796,Q14739,P02545,Q96A33,P16435,Q14696,Q92581 12 +Urinary glycosaminoglycan excretion 0.662742944596666 1.5702403280456554 0.1163592106927844 1.0 0.4596287265013625 8 P04066,P08236,P54802,P16278 4 +Abnormal retinal vascular morphology 0.4317873364471592 1.5687023218203515 0.1167173173507829 1.0 0.4598760799247304 52 Q9NZJ7,P10619,P21964,P07602,Q9Y4P3,P21912,P03886,P16278,Q13510,P17900,P38435 11 +Crumpled long bones 0.7060972183197441 1.5673267678409637 0.1170383316856427 1.0 0.4607389211188654 2 P07237 1 +Abnormality of the gallbladder 0.4374061830954815 1.5664968340701468 0.1172323491731017 1.0 0.4607389211188654 40 Q9NZJ7,P21964,P07602,P04062,Q96A33,Q9Y4P3,O95202,P22830,Q9UBM7,Q5H8A4 10 +Ectopic calcification 0.4240656552355252 1.5636765797483243 0.1178935405158172 1.0 0.4624306685421926 61 P00403,O75381,P02545,O75844,P04062,O75431,P05067,P35670,P03886,O00116,O60313,P56589,Q14739,P38435,Q9UBM7,P23786,P40855,P08236 18 +Hypocalciuria 0.7052542849114927 1.5633940755179074 0.1179599327979763 1.0 0.4624306685421926 2 P53680 1 +Hypermagnesemia 0.7052542849114927 1.5633940755179074 0.1179599327979763 1.0 0.4624306685421926 2 P53680 1 +Inappropriate behavior 0.5204715947018284 1.5602229833586942 0.1187071961328956 1.0 0.4630418850384764 20 Q9NZJ7,P07602,P35670,P17900,Q96RL7 5 +Palmar pits 0.7990827451954322 1.560126855083365 0.118729906448644 1.0 0.4630418850384764 3 P16615 1 +Talipes calcaneovalgus 0.7075634287673538 1.560074649322611 0.1187422414926442 1.0 0.4630418850384764 7 Q9NR77,Q9UBM7 2 +Limb muscle weakness 0.3818641817027516 1.5598642299266572 0.118791969036724 1.0 0.4630418850384764 88 P53007,P35670,P12235,Q99720,Q96RL7,P50402,Q969G3,Q8TB36,Q9BTV4,Q7RTS9,Q969X5,Q13510,P05023,Q9NR77,Q96T60,Q13126,Q14739,P02545,O15269,P40939 20 +Abnormal muscle fiber protein expression 0.660039703339073 1.5573346959307537 0.1193910419159611 1.0 0.4630418850384764 8 P50402,P02545 2 +Abnormal corneal epithelium morphology 0.5449892535172036 1.557154218416304 0.1194338749528995 1.0 0.4630418850384764 17 O75844,Q14739,P51648,P02545 4 +Narrow nasal ridge 0.7068534153652611 1.5568959401442668 0.119495193519624 1.0 0.4630418850384764 7 O75844,P02545 2 +Abnormal lumbar spine morphology 0.6214902057044136 1.556857686747153 0.1195042774622754 1.0 0.4630418850384764 10 P04062 1 +Sensory neuropathy 0.436790825388718 1.555403269108799 0.11985005602962 1.0 0.4637049974766783 36 Q15041,O95140,Q8IV08,P03886,O60313,O15269,P40939,Q96RL7,P00403 9 +Pericardial effusion 0.6588595627561402 1.551696697869974 0.1207348131922072 1.0 0.4654920254289146 8 Q14108,P04062,P02545 3 +Chronic fatigue 0.6314199062507042 1.5483521640382767 0.1215375316447109 1.0 0.4678142912194191 9 Q9NZJ7,P07602 2 +Abnormal retinal morphology 0.3520442929811441 1.547094583995706 0.1218404397480392 1.0 0.468547855309488 236 O43924,Q9NZJ7,P10619,Q10713,Q13432,P01889,Q9UHX1,O76024,P16278,Q5H8A4,Q8NCH0,P21964,Q9UG56,O75503,P50897,P21912,O95202,Q6P4Q7,Q5XKP0,P04062,P03886,P51648,Q13510,Q9UM00,P02545,P00403,O60313,P07602,O43505,P51812,Q7LGA3,Q8NHS3,Q9P0J0,Q9Y4P3,P53701,P17900,O14773,P40939,Q9Y375,P38435,Q9Y287 41 +Vocal cord paralysis 0.506678876848624 1.546728131983673 0.1219288164919742 1.0 0.468547855309488 22 P50402,Q9NR77,O95140,Q8TB36,P21912,P02545,Q9BTV4 7 +Thoracic kyphosis 0.5430475206785574 1.5451649198713855 0.1223063772439077 1.0 0.4696122330195765 17 Q9UHX1,P04062,P51648 3 +Decreased ldl cholesterol concentration 0.7989997413902977 1.5442928869265884 0.1225173949832605 1.0 0.4700359220845056 4 P37268 1 +Calcinosis 0.772244956603605 1.542506176791251 0.1229506381118423 1.0 0.4709241422019622 5 O75844,Q14739 2 +3 methylglutaconic aciduria 0.6293636420122065 1.5380983600074427 0.1240245669400876 1.0 0.4734838127908989 9 Q5XKP0,Q9BUB7,Q9NVI7,Q9H078 4 +Abnormal circulating free fatty acid concentration 0.7961765532752201 1.532919966103625 0.1252955757460325 1.0 0.4748876084932711 4 P49748,P40939,O75431 3 +Very long chain fatty acid accumulation 0.7488045007032377 1.531739014808481 0.1255868506379456 1.0 0.4751399582979949 6 O75381,P51659,Q5T8D3,P56589,P40855 5 +Status epilepticus 0.427166747594255 1.5298261829267554 0.1260597588208765 1.0 0.4751399582979949 53 P05023,Q9NZJ7,P07602,P42892,Q01105,P49589,O43292,Q15392,Q13510,P51970 10 +Postaxial foot polydactyly 0.627405294801477 1.5283254735226055 0.1264317482881454 1.0 0.4751399582979949 9 O43924,Q10713,Q14739 3 +Abnormality of the 5th toe 0.627405294801477 1.5283254735226055 0.1264317482881454 1.0 0.4751399582979949 9 O43924,Q10713,Q14739 3 +Abnormality of the musculature of the upper arm 0.6537865628223167 1.5274348442214072 0.1266529175047188 1.0 0.4751399582979949 8 P50402,Q9BTV4,P02545 3 +Proximal upper limb amyotrophy 0.6537865628223167 1.5274348442214072 0.1266529175047188 1.0 0.4751399582979949 8 P50402,Q9BTV4,P02545 3 +Abnormal number of permanent teeth 0.7905670873591151 1.5253746171396323 0.1271656861046843 1.0 0.4754890413051364 3 Q12959 1 +Clonic seizure 0.6153158979301461 1.525246418340451 0.1271976467316589 1.0 0.4754890413051364 10 P07602 1 +Slow decrease in visual acuity 0.6526349189594971 1.521921251867778 0.1280288134708616 1.0 0.4778309593089151 8 Q969G3,P03886 2 +Eyelid myoclonus 0.6144360660669987 1.52073566069695 0.1283261859215585 1.0 0.4784472339605307 10 Q13510,Q01105 2 +Weakness of muscles of respiration 0.4325622680537425 1.519268864304833 0.1286948335687994 1.0 0.4784472339605307 38 Q8TD16,P50402,O14908,P53007,Q9BTV4,P22626,O95140,Q7RTS9,Q969X5,P10253,P02545,Q13510,P43243,P12235,P36551 15 +Abnormal sensory nerve conduction velocity 0.7457455575869747 1.5188396772733308 0.1288028559580352 1.0 0.4784472339605307 6 Q9NR77,O15269 2 +Abnormal tongue morphology 0.4031664503809634 1.518764746873672 0.1288217224652705 1.0 0.4784472339605307 74 O43924,Q10713,Q03252,P20700,P02545,Q7LGA3,P01889,O75844,O75431,Q96A33,Q9Y4P3,P21912,P10253,P16278,Q6NUK1,O60826,Q9UBM7,Q96RL7 18 +Abnormal atrioventricular valve morphology 0.4324700264737205 1.517188515428882 0.1292190950620524 1.0 0.4784490688699467 36 P55795,P21964,P51812,O75844,P04062,O75431,Q9Y4P3,P53701,P02545 9 +Hypoglycemic seizures 0.697382333553975 1.514429540772193 0.1299169316373825 1.0 0.4795281186332103 7 Q16836,Q13423,P40939 3 +Abnormal brain lactate level by mrs 0.6013895338908442 1.5141633230307348 0.1299844214296097 1.0 0.4795281186332103 11 P03886,P21912 2 +Scanning speech 0.7877765090962354 1.5139758426137355 0.1300319665753224 1.0 0.4795281186332103 3 O14773 1 +Abnormalities of placenta or umbilical cord 0.5282465009652696 1.511801055816636 0.1305844807484917 1.0 0.4801990882151198 18 O75844,Q6PGP7,P02545,P16278,P16435 5 +Confusion 0.5183964076406253 1.5113924496965627 0.1306884918818824 1.0 0.4801990882151198 19 Q9Y619,P01889,O00255,Q9NZ08,O96008,P40939,Q16836,P05067,Q9UJS0 9 +Abnormality of hair pigmentation 0.4845363325391535 1.5112675756548333 0.1307202915231136 1.0 0.4801990882151198 25 Q13126,Q9UM00,P02545,P37268,Q9UBM7 5 +Abnormal pyramidal sign 0.3610075859039466 1.5105799874232635 0.1308954959584365 1.0 0.4803083710838604 130 Q9NZJ7,Q8NI60,P01889,P49589,O75477,Q99720,Q8WVX9,O43681,O95140,P21912,O15121,Q8N2K0,P20700,Q6DKK2,P51572,Q92796,P51648,O60313,P41440,Q9NR77,Q9Y619,P07602,P51812,Q9P0J0,Q8TB37,Q9H078,P35637,P17900,O14773,P40939,P07196 31 +Thickened ribs 0.764463764563073 1.5103435518692416 0.130955784191423 1.0 0.4803083710838604 5 P54802 1 +Flaring of rib cage 0.7866267890318642 1.5092781320222053 0.1312277206801413 1.0 0.4806787183695949 3 P16278 1 +Skin rash 0.4949773566248213 1.5091413620695433 0.1312626613667238 1.0 0.4806787183695949 23 Q06136,Q14739 2 +Abnormality of metacarpal epiphyses 0.7639514494864218 1.5082240668941334 0.1314971896610122 1.0 0.4811601712596128 5 P16435,P51812 2 +Osteolysis involving bones of the feet 0.742557839781578 1.5053869709265524 0.1322246168418042 1.0 0.4822447797052047 6 O75844,P02545 2 +Foot acroosteolysis 0.742557839781578 1.5053869709265524 0.1322246168418042 1.0 0.4822447797052047 6 O75844,P02545 2 +Ventricular tachycardia 0.5751782347151253 1.5050403424832566 0.132313705142024 1.0 0.4822447797052047 13 P49748,Q9BTV4,P23786,O43772 4 +T lymphocytopenia 0.6107431323915448 1.5017861438784912 0.1331523479106784 1.0 0.4831895245470023 10 Q13432 1 +Abnormality of circulating adrenocorticotropin level 0.5988793758041133 1.5009258683896871 0.1333747365393995 1.0 0.4831895245470023 11 Q13423,Q969G3,O00255,O00170,P16435 5 +Central apnea 0.6482327885907746 1.5008264044455295 0.1334004673535447 1.0 0.4831895245470023 8 Q9NZJ7,Q10713,P07602 3 +Elevated hemoglobin a1c 0.7844641006833394 1.5004393238965947 0.1335006396799385 1.0 0.4831895245470023 3 O75431 1 +Adipose tissue loss 0.61031403120195 1.499582599791377 0.133722557731946 1.0 0.4832435155189289 10 O75844,O75431,P02545 3 +Raynaud phenomenon 0.7407636463633627 1.4978106473806945 0.1341824536966109 1.0 0.4840621097661561 6 O75844,Q14739 2 +Underdeveloped supraorbital ridges 0.573396654257207 1.4950898085604671 0.1348910052983005 1.0 0.4856685438358959 13 O75381,P56589,Q6PGP7,Q6NUK1,P16435,P40855 6 +Recurrent acute respiratory tract infection 0.7831342215418767 1.495002814069957 0.1349137077222439 1.0 0.4856685438358959 3 Q03519 1 +Head tremor 0.5602443843527305 1.492540431826089 0.1355575261100585 1.0 0.4858771393393211 14 P35637,P20700,Q99720,Q96RL7 4 +Epiphyseal stippling 0.5727904121481017 1.4917020976831468 0.1357772589640611 1.0 0.4858771393393211 13 O75381,P40855,Q14739,O00116,P56589,Q9UBM7,P38435 7 +Abnormal mitochondrial number 0.6898005057600439 1.4912028948842966 0.1359082338781612 1.0 0.4858771393393211 2 Q9BQP7 1 +Congenital ptosis 0.6898005057600408 1.4912028948842817 0.1359082338781652 1.0 0.4858771393393211 2 O75962 1 +Reduced subcutaneous adipose tissue 0.619749134348795 1.4900512932716996 0.1362107495570381 1.0 0.4862140593897639 9 O75844,P02545 2 +Prominent antihelix 0.7816188870151797 1.488806949507716 0.1365382117951239 1.0 0.4862720436662781 3 P98175,O14656 2 +Cold induced muscle cramps 0.7816177459714075 1.4888022835546777 0.1365394408324032 1.0 0.4862720436662781 3 Q9NR77 1 +Decerebrate rigidity 0.7589873444108028 1.4876756752547486 0.136836445535899 1.0 0.4868887159120577 5 Q9NZJ7,P07602,P16278 3 +Profound global developmental delay 0.5511810209424176 1.4873546891122655 0.1369211574196898 1.0 0.4868887159120577 15 O75381,O60313,P56589,Q9H490,P37268,Q92581 6 +Abnormal circulating fatty acid concentration 0.5145445816928896 1.4861777868449244 0.1372321014292605 1.0 0.4876230453373041 19 P49748,O75381,O43772,O75431,P40939,P56589,P23786,P40855 8 +Symphalangism of middle phalanx of finger 0.6883956167462759 1.4846325704188792 0.1376411826647627 1.0 0.4887047010355721 2 O60828 1 +Vertebral compression fracture 0.5236151712360103 1.4823022089773354 0.1382599008102665 1.0 0.4905089952011109 18 Q14108 1 +Neck flexor weakness 0.7798523898893323 1.4815825487282563 0.138451405307082 1.0 0.4905089952011109 3 Q99720 1 +Titubation 0.5950574837701786 1.4807462124635034 0.138674214436655 1.0 0.4907190197434606 11 P35637,P20700,Q99720,Q96RL7 4 +Agitation 0.4518053531276173 1.4805219293090872 0.1387340128638612 1.0 0.4907190197434606 31 P42892,P04062,O96008,P35637,Q15165,P48449 6 +Psychotic mentation 0.736336912271941 1.4791044051331343 0.1391124130514183 1.0 0.4916849784534989 6 P03886 1 +Opisthotonus 0.4799903069468694 1.4777630114525373 0.1394712219870009 1.0 0.4918362050281776 25 Q9NZJ7,Q2TAA5,P07602,P11117,P04062,Q9H078,O60313,Q99720,P51970 9 +Proportionate short stature 0.4277910269627797 1.4756598739767106 0.1400352230111079 1.0 0.4930188415244398 36 P10619,Q7RTS9,P40939,P21912,Q14739,Q15392,P53701,P16278 8 +Basal ganglia calcification 0.6166053182571238 1.4743049579607603 0.1403995008696625 1.0 0.4930188415244398 9 P03886,P00403 2 +Progressive sensorineural hearing impairment 0.581760821009918 1.47336984060065 0.1406513379547127 1.0 0.4930188415244398 12 O76024,P03886,P00403 3 +Blindness 0.3741505691885826 1.4716487337720257 0.1411157582072497 1.0 0.4936880810664289 89 Q9NZJ7,P01889,P16278,Q969G3,O43676,Q9Y6M9,Q8N183,P50897,P21912,O96000,Q86Y39,P03886,O75380,P07602,O43505,Q8NHS3,Q8TB37,P53701,P17900,Q9Y375,Q9NPL8 21 +Shoulder girdle muscle weakness 0.5813314625958054 1.4710353344900204 0.1412815613265372 1.0 0.4936880810664289 12 Q9NZJ7,P07602,O14979,P43243,P12235 5 +Decreased adipose tissue 0.539750276872432 1.469880674560354 0.1415940744573194 1.0 0.4936880810664289 16 Q03252,O75844,O75431,P02545,Q6NUK1 5 +Tachycardia 0.4746635533540425 1.469677717428656 0.1416490604233558 1.0 0.4936880810664289 26 P49748,P42892,O43772,P21912,P02545,P23786,Q9BTV4 7 +Atlantoaxial abnormality 0.7541931945282654 1.4678117704314824 0.1421553593354887 1.0 0.4949465866796397 5 Q8NCH0,Q9NWM8 2 +Abnormal circulating long chain fatty acid concentration 0.7539039223988316 1.4666126384426446 0.142481460000277 1.0 0.4957123224599803 5 P56589,P23786,O75381 3 +Inability to walk 0.3730250466331851 1.4653365288199118 0.1428291249948488 1.0 0.4965518872680186 90 Q15041,Q9NVI7,P12235,Q99720,Q96RL7,O14949,Q96CU9,Q8WVX9,O75503,Q8TB36,P21912,Q92581,P82930,Q7RTS9,O43292,Q13510,Q9NR77,P35637,O15269,Q96N66 20 +Excessive salivation 0.4440697077740676 1.4615856369362583 0.1438547926725895 1.0 0.4990029918189601 32 Q9NR77,P55795,Q03252,P51812,P01889,P35670,Q96RL7,Q92581 8 +Amelogenesis imperfecta 0.7780953790638161 1.4599467978373974 0.1443046962138017 1.0 0.4991392145556253 4 Q9HC07 1 +Peripheral hypermyelination 0.7745493069418956 1.4598849964353748 0.1443216833690499 1.0 0.4991392145556253 3 Q9NR77 1 +Postural instability 0.5103684000696379 1.4587809967520489 0.1446253945682525 1.0 0.4995644177488855 19 P41440,Q9NR77,Q96T60,O75503,P04062 5 +Polar cataract 0.751864686977642 1.4581575213661353 0.1447971294088506 1.0 0.4995644177488855 5 P08670,Q9Y287 2 +Inverted nipples 0.6392902532778444 1.457883667493162 0.144872611186976 1.0 0.4995644177488855 8 P56589,Q2TAA5 2 +Tremor 0.338430590318733 1.4563707513159865 0.1452901565585453 1.0 0.4999070327324415 174 O43924,Q14108,Q9NZJ7,Q10713,Q8NI60,P35670,O76024,Q9BUB7,P12235,Q99720,Q6P4A7,Q96RL7,O75503,O43681,P21912,P20700,Q9NQZ5,P04062,Q6DKK2,P03886,O43292,Q13510,Q9UJS0,O60313,P41440,Q9NR77,P07602,Q96T60,Q9Y4P3,O14656,O14773,Q9Y287 32 +Protruding tongue 0.566386500039588 1.4558648161442227 0.1454299935924843 1.0 0.4999070327324415 13 Q6NUK1,P20700,Q10713,Q96RL7 4 +Abnormality of glycolipid metabolism 0.6388184169312916 1.4556146429684504 0.1454991778228187 1.0 0.4999070327324415 8 Q9NZJ7,P07602,P17900 3 +Heterogeneous 0.42191746900401 1.455585221667716 0.1455073158028246 1.0 0.4999070327324415 48 Q9BQE5,P61916,Q9NR77,P21964,P01889,O75844,P40939,Q8TB36,P03886,P02545,P12235 11 +Dyschromatopsia 0.7306789789980813 1.4551685918396406 0.145622593711491 1.0 0.4999262008739438 6 Q9H061 1 +Acute hepatic failure 0.5534995594626738 1.453646625230563 0.1460443031777925 1.0 0.500054410958375 14 P08574,P40939,P35670 3 +Postaxial hand polydactyly 0.5659640303046022 1.4534973395429818 0.1460857178297758 1.0 0.500054410958375 13 O43924,Q9UM00,Q10713,Q14739 4 +Babinski sign 0.3717001773411671 1.4486744386819714 0.1474285221125488 1.0 0.5031752702803295 90 Q9NZJ7,O75477,Q99720,Q8WVX9,O43681,O95140,P21912,O15121,Q8N2K0,P20700,Q6DKK2,Q92796,O60313,P41440,Q9NR77,P07602,P51812,Q8TB37,P35637,O14773,P40939,P07196 22 +Abnormal enchondral ossification 0.4478502747997918 1.4481330200105476 0.1475798524092102 1.0 0.5033238355723905 31 Q9UG56,O75381,Q7RTS9,Q96HY6,O95202,O00116,Q14739,P56589,P38435,Q9UBM7,P40855,P08236 12 +Abnormal electroretinogram 0.4243319965368063 1.445424478732383 0.1483386917645159 1.0 0.5055425925901643 35 O43924,P50897,O14773 3 +Abnormal iliac wing morphology 0.5642772424422053 1.4440408134087583 0.1487274951630062 1.0 0.5060577315758913 13 P16278,Q8TAA9,P51812 3 +Myopathy 0.3598176350322866 1.4437297607192554 0.1488150065225313 1.0 0.5060577315758913 105 Q03252,P53007,P13473,O76024,Q53H12,P23786,P12235,Q96RL7,Q8NCH0,P50402,O43676,Q9NWM8,P09493,Q9Y6B6,P21912,Q9NWS8,Q9BTV4,Q86Y39,P03886,Q969X5,P00403,P42167,O60313,Q13126,Q8TB37,Q9Y4P3,P02545,P40939,Q9Y375 29 +Hyperintensity of cerebral white matter on mri 0.5026919896865955 1.4416112531095449 0.1494120720782206 1.0 0.5067443777110922 20 Q9NZJ7,P20700,P07602,O43681,O75503,P21912,P17900 7 +Fasting hyperinsulinemia 0.7478428325311743 1.4414731342707618 0.1494510619207911 1.0 0.5067443777110922 5 O00255,P40939,P02545 3 +Fat malabsorption 0.6093388227662258 1.437845954848218 0.1504777670394816 1.0 0.5090727197182844 9 Q14739 1 +Hypotension 0.4566882002527977 1.4375073856408838 0.1505738757616086 1.0 0.5090727197182844 29 Q13423,Q9NZJ7,P07602,O43772,O43681,P04062 6 +Decreased calvarial ossification 0.77212658198337 1.4358126926942223 0.1510556470960455 1.0 0.5103242716225307 4 O75844 1 +Quadriceps muscle weakness 0.7720336580113757 1.4354368140912035 0.1511626617378367 1.0 0.5103242716225307 4 P12235 1 +Abnormality of bladder morphology 0.5975957608121367 1.4341171197881477 0.1515388432048159 1.0 0.5104513051245255 10 Q9NWM8,P16435 2 +Xerostomia 0.5624197170896772 1.4336198825680024 0.1516807664571877 1.0 0.5104513051245255 13 Q15165 1 +Muscle hypertrophy of the lower extremities 0.6084671060862036 1.4334664378740902 0.151724583631764 1.0 0.5104513051245255 9 Q9NR77,P02545 2 +Sudden episodic apnea 0.7713090495547618 1.432505611919577 0.151999173198428 1.0 0.5106731628492219 4 O43772 1 +Alkalosis 0.7242381443137893 1.427886384774997 0.1533245631064517 1.0 0.5129447399671538 6 P01889,Q9Y619,O00170 3 +Abnormal oral frenulum morphology 0.5241298545663423 1.427738738693526 0.1533670715344071 1.0 0.5129447399671538 17 O43924,O75844 2 +Rhabdomyolysis 0.5484070315271946 1.4242078713009707 0.1543863070093785 1.0 0.5154142105184981 14 P40939,Q86VD7,O43772,P23786 4 +Punctate cataract 0.7657938300286401 1.4240341075607712 0.1544365989538185 1.0 0.5154142105184981 3 P08670 1 +Upper limb postural tremor 0.7648049664206076 1.4199831416444408 0.1556125890555599 1.0 0.518597557673383 3 Q9NR77 1 +Bradycardia 0.5834251098121681 1.419152125346286 0.1558546699514651 1.0 0.518692713805239 11 O43772,Q9BTV4,P02545 3 +Limb joint contracture 0.3560443084730876 1.417769141671591 0.1562581761989909 1.0 0.5196363423597499 118 Q86XL3,Q5JTV8,P27635,Q9HC21,Q9BUB7,P37268,O75477,P23786,Q99720,P50402,Q8IWS0,P49711,P21912,Q15392,Q9BTV4,Q8N2K0,Q969X5,Q8IZA0,P16435,O60313,Q9NR77,Q9Y619,P42892,Q7LGA3,O75844,O14656,P35637,P02545,P07196 29 +Acne inversa 0.7675268181705824 1.4172014202396332 0.1564240466821298 1.0 0.5196375432032292 4 Q92542,Q9H488 2 +Broad based gait 0.4676346609448781 1.4168167113995176 0.1565365224830981 1.0 0.5196375432032292 26 P49589,P04062 2 +Delayed fine motor development 0.5710847134833825 1.4152093101243903 0.1570071356106712 1.0 0.5204923417307475 12 P49589,P16435 2 +Dysesthesia 0.6752987231531237 1.4149847318371749 0.1570729726919304 1.0 0.5204923417307475 7 Q9NR77 1 +Joint swelling 0.6301709767663213 1.4139758083779814 0.1573690056023315 1.0 0.5207820583612267 8 Q13510 1 +Diffuse cerebral atrophy 0.5035183992239523 1.4137150765176385 0.1574455768543929 1.0 0.5207820583612267 19 Q9NZJ7,Q10713,P07602 3 +Generalized muscle weakness 0.4381817646041833 1.4123392367138226 0.1578500985794044 1.0 0.5215867730129082 32 P53007,P35637,P40939,Q15165,P21912,P10253,P12235 7 +Areflexia of lower limbs 0.4871427645468811 1.4107917413546462 0.1583060303566923 1.0 0.522155962765231 22 Q9NR77,Q15041,O95140,O60313,O75477,P12235,Q96RL7 7 +Abnormal large intestine physiology 0.4871176506265755 1.4106160418091842 0.1583578589153067 1.0 0.522155962765231 22 Q9NZJ7,P21964,P07602,O43681,Q8TAA9,Q92581 6 +Hypoplastic pelvis 0.672098904186565 1.4083541413867726 0.1590262312327763 1.0 0.523251214676415 2 Q15738 1 +Tube feeding 0.3947005325038818 1.407758548819224 0.1592025783215274 1.0 0.5234625621008531 73 Q9NZJ7,P07602,Q9UHX1,Q01105,Q9NZ01,Q9H490,P37268,Q96N66,Q99720 9 +Abnormally lax or hyperextensible skin 0.4189821750906642 1.4064295093250414 0.1595966227602756 1.0 0.5243889033551914 43 Q8NCH0,P51812,Q9NWM8,O96000,Q9UHX1,P04062,Q9Y4P3,P38435 8 +Abnormal pharynx morphology 0.4179440307838296 1.4044447934585949 0.1601864401952171 1.0 0.5257867947157817 45 Q03519,Q969G3,Q13432,P01889,P08236,Q9H0U3,Q7RTS9,Q03518,P16278,Q13510,P00813,P54802,Q86YV9 13 +Recurrent paroxysmal headache 0.5806159970524152 1.4042403419619836 0.1602472925424196 1.0 0.5257867947157817 11 P03886,P21912 2 +Cerebral white matter atrophy 0.4859983707906081 1.4027830878753391 0.1606815316612788 1.0 0.5261161014676355 22 Q8N766,P20700,Q2TAA5,O75503,P51572,O60313,P51970 7 +Abnormal tissue metabolite concentration 0.5286540544309651 1.4024945273519271 0.1607676235921442 1.0 0.5261161014676355 16 Q9NZJ7,P07602,O75381,O43681,Q9Y276,Q5T8D3,P17900,P56589,P40855 9 +Retinal degeneration 0.4091922484425534 1.4023914380751177 0.1607983886901511 1.0 0.5261161014676355 60 Q10713,Q9UG56,Q7LGA3,O75503,P04062,P50897,P51648,O14773,Q13510,P02545,O60313 11 +Palmoplantar cutis laxa 0.6704130373700425 1.4004586020702667 0.1613760318975721 1.0 0.5268983866641708 2 Q9Y487 1 +Papule 0.4961545847458522 1.3977137457723805 0.1621990448091377 1.0 0.5291558101275362 20 P16615,O75844,P21912,P02545,P38435 5 +Abnormal endocrine physiology 0.7372306345468305 1.397397425274472 0.1622940929755048 1.0 0.5291558101275362 5 Q13724,Q13423,P16435 3 +Aplasia hypoplasia of the lungs 0.4188744074997784 1.3958113014737927 0.1627713262090866 1.0 0.529971633242835 37 O96000,O75844,Q16134,Q8TAA9,O95202,Q14739,P02545,Q9UBM7,Q5H8A4 9 +Abnormal hdl cholesterol concentration 0.7584900215931856 1.3941059962985307 0.1632855987231929 1.0 0.5312755821871692 3 P02545 1 +Increased ldl cholesterol concentration 0.5892500880160354 1.3910072492335517 0.1642232285081113 1.0 0.5332115812965034 10 Q8N511,P02545,Q9BTV4,P50402 4 +Hyperlipoproteinemia 0.5892500880160354 1.3910072492335517 0.1642232285081113 1.0 0.5332115812965034 10 Q8N511,P02545,Q9BTV4,P50402 4 +Elevated gamma glutamyltransferase level 0.7564756420272553 1.3858491973262692 0.1657929562335962 1.0 0.5374857049502465 3 Q5XKP0 1 +Abdominal distention 0.4713033896488861 1.3848958157672742 0.1660843266573228 1.0 0.5377584751477396 24 P14314,Q9NZJ7,P07602,O43681,P04062,Q7RTS9,Q96HY6,Q9Y6B6,Q01844 9 +Shallow orbits 0.5985768683312993 1.3836966139591096 0.1664513708113846 1.0 0.5380651315250617 9 P07237,O75844,O75431,P02545 4 +Ulnar claw 0.7587714388739131 1.3817498690629388 0.1670485164191655 1.0 0.5386391734537872 4 Q8TB36,Q9NR77 2 +Abnormal peripheral nervous system physiology 0.4070861855429963 1.380799918433609 0.1673404886008602 1.0 0.5388363732947701 60 Q9NZJ7,Q8N2K0,P20700,Q9NR77,Q9Y619,P07602,Q96T60,Q9NQZ5,O43681,O95140,Q8TB36,O15269,O60313,Q13724,O15121,P02545,Q99720,Q96RL7 18 +Abnormal cardiac ventricular function 0.4883519380839656 1.3803450735959268 0.1674804231478097 1.0 0.5389152968140067 21 P49748,O75844,P03886,P21912,P02545,P12235,P00403 7 +Vertical nystagmus 0.6659173925259877 1.3794017179218565 0.1677709298859984 1.0 0.5394782862518778 2 P50542 1 +Renal hypoplasia 0.4168322142556007 1.3778224501825929 0.1682581128088802 1.0 0.5400274717509337 36 O43924,P21964,Q9UHX1,Q6PGP7,Q9Y4P3,Q96I36,Q9UBM7 7 +Absence of subcutaneous fat 0.6666026803425205 1.3756837549666123 0.168919563523437 1.0 0.5416795618756371 7 O75844 1 +Clonus 0.4337683853950856 1.3752984826953083 0.1690389267330656 1.0 0.5416902875200298 32 P07602,P49589,Q99720 3 +Abnormal echocardiogram 0.757067934100129 1.3748487555778794 0.1691783390594459 1.0 0.5417652023789801 4 P49748 1 +Poor motor coordination 0.5152189920846574 1.372064245202843 0.1700434388659337 1.0 0.5429119842334121 17 O75503,Q10713,P35670 3 +Delayed ability to stand 0.7530589286228675 1.3718422365577378 0.1701125556173783 1.0 0.5429119842334121 3 P21912 1 +Bilateral sensorineural hearing impairment 0.457416332715824 1.3715402706653372 0.170206598819621 1.0 0.5429119842334121 27 Q9NZJ7,P07602,O43681,P03886,P00403 5 +Abnormal delivery 0.4756642791476589 1.371451899241506 0.1702341282753727 1.0 0.5429119842334121 23 Q9Y619,P02545,O75844,P33991,P50454,Q969X5,O60313,Q9UBM7 8 +Abnormality of the vasculature of the eye 0.3913629022241623 1.3704877671734734 0.1705346914083165 1.0 0.5430861582214643 73 Q9NZJ7,P10619,P21964,P07602,P01889,Q9Y4P3,P21912,P03886,P16278,Q13510,Q14739,P17900,P38435 13 +Neoplasm of the oral cavity 0.5507849783249346 1.3681838289265444 0.1712545420842013 1.0 0.5438084071983527 13 O43924 1 +Chondrocalcinosis 0.6648215426098747 1.367625574690558 0.1714293069594852 1.0 0.5438084071983527 7 P02545,P35670 2 +Neonatal death 0.5309070071084036 1.3671973439447085 0.1715634576575655 1.0 0.5438084071983527 15 O96000,Q9NVI7,P04062,Q16134,Q14739 5 +Barrel shaped chest 0.7292180238321564 1.3640757450076757 0.1725437276557671 1.0 0.5461740097795095 5 Q7RTS9,Q14739 2 +Occipital encephalocele 0.7089040834085611 1.3628048457570012 0.1729440235406698 1.0 0.5470702208071732 6 Q10713,Q6ZXV5 2 +Global brain atrophy 0.4908924635808437 1.3622761985345202 0.1731107361875963 1.0 0.5470706982469912 20 Q9NZJ7,P07602 2 +Glucose intolerance 0.3521493647991248 1.3614099858578592 0.1733841621370502 1.0 0.5470706982469912 113 Q03252,Q8TAA9,O76024,P49589,Q06136,P12235,O43676,Q9Y6M9,O75431,Q8N183,O96000,Q86Y39,P03886,O75380,O60313,P00403,O75844,Q8TB37,Q9Y4P3,P02545,Q9Y375,Q9NPL8 22 +Pace of progression 0.3333579186162239 1.361166297634724 0.1734611421319225 1.0 0.5470706982469912 173 Q5JTV8,Q14108,Q10713,Q03252,P28288,O75477,P12235,Q99720,Q96RL7,Q8N766,P50402,Q9Y6M9,Q8N183,Q8TB36,Q5XKP0,O15121,Q9BTV4,P20700,Q9NQZ5,P04062,P82930,O14773,Q13510,P54802,O60313,P05023,P41440,Q9NR77,Q96T60,Q13126,Q9P0J0,Q8NHS3,Q9H078,P27544,P02545,O95470,Q8IV08 37 +Dystrophic toenail 0.6633460838180891 1.360948298440199 0.1735300287221661 1.0 0.5470706982469912 7 O75844,P02545 2 +Abnormality of facial adipose tissue 0.7532094032712262 1.3592138935981812 0.1740788199340721 1.0 0.547373977515385 4 O75844,P02545 2 +Focal non motor seizure 0.572074469370645 1.3588164978366817 0.1742047441375593 1.0 0.547373977515385 11 P22466 1 +Mortality aging 0.3519232796782691 1.3587923204905654 0.1742124074936522 1.0 0.547373977515385 116 Q9NZJ7,Q9HC21,Q9NVI7,Q9BUB7,P16278,P56589,Q6NUK1,O60508,Q16134,O75431,Q9Y3C6,Q9NWS8,P40855,Q92581,O75381,O96000,P04062,Q9BT22,O43819,P16435,P49748,P07602,P51812,O75844,Q9Y4P3,O14656,Q8TCJ2,Q14739,O60826,P02545,P05067,Q96IX5,Q9NPL8 33 +Abnormal lung lobation 0.5485928693985299 1.355825068766811 0.1751548330849308 1.0 0.5484895477354407 13 Q9UBM7,Q9UHX1,Q14739 3 +Hypoproteinemia 0.7484541877459278 1.3529616258295205 0.1760678900453443 1.0 0.5504325947603215 3 P49748,Q9UJS0 2 +Aplasia of the phalanges of the hand 0.7483647412816671 1.3525948435894195 0.1761851006664239 1.0 0.5504325947603215 3 P02545 1 +Elevated circulating long chain fatty acid concentration 0.7481731309724596 1.351809127436797 0.1764363835076252 1.0 0.5506560659071539 3 P23786,P40855 2 +Macular purpura 0.520141910431128 1.350585986906068 0.1768280921543237 1.0 0.5511417638641771 16 P04062,P38435 2 +Eeg with spike wave complexes 0.5199940272254917 1.3496826246190825 0.1771178081246116 1.0 0.5514104943900041 16 Q96T60,Q9NQZ5,Q14108,O75503 4 +Orthostatic hypotension 0.519977345524125 1.349580719244365 0.1771505122263881 1.0 0.5514104943900041 16 Q9NZJ7,O43681,P04062,P07602 4 +Vocal cord paresis 0.7250456020827261 1.3467119951270543 0.1780730075244574 1.0 0.5535438562794219 5 O14908,Q8TB36,O95140 3 +Achilles tendon contracture 0.5468107200260429 1.3457710333993331 0.1783763698960538 1.0 0.553976914621069 13 P50402,O60313,Q9BTV4,P02545 4 +Arm dystonia 0.7247192313027826 1.3453534790844384 0.1785111108926464 1.0 0.553976914621069 5 Q99720 1 +Premature rupture of membranes 0.7041523775267152 1.3426058631654147 0.1793996308408498 1.0 0.5554488570264775 6 P02545,O75844,P50454 3 +Abnormal femoral neck head morphology 0.4098580029277232 1.3398177887520195 0.1803045908800757 1.0 0.5573076830444598 48 P51812,P02545,Q7LGA3,O75844,O75431,Q7RTS9,Q14739,P16278,Q96A33 9 +Brushfield spots 0.7483834692156237 1.339653298772473 0.1803580871878729 1.0 0.5573076830444598 4 P56589,P40855,O75381 3 +Echolalia 0.5896938795292564 1.3388781041010842 0.1806103588533374 1.0 0.5577180988665559 9 Q9UJS0,Q9UHX1,P53701 3 +Leg muscle stiffness 0.6569261028378746 1.337285632097921 0.1811294191188115 1.0 0.5589512609819769 2 Q6PI48 1 +Cardiorespiratory arrest 0.7223887248845972 1.3356515679806171 0.1816631864792899 1.0 0.5599319608298952 5 O43772 1 +Skeletal muscle hypertrophy 0.4096365725645549 1.3350445232267856 0.1818617748067597 1.0 0.5599319608298952 47 Q9NR77,Q10713,P53007,P02545,Q7LGA3,Q9Y4P3,P21912,P10253,P16278,Q96A33 10 +Anterior pituitary dysgenesis 0.6563641472323651 1.3346535683224037 0.1819897568394044 1.0 0.5599319608298952 2 Q15233 1 +Rimmed vacuoles 0.5175245124419812 1.3345898329569783 0.1820106274233597 1.0 0.5599319608298952 16 P50402,O14908,P22626,O14979,P02545,Q9BTV4 6 +Infantile axial hypotonia 0.567335610451501 1.3335652867337875 0.1823463658276551 1.0 0.5599319608298952 11 Q9NZJ7,P07602 2 +Abnormality of retinal pigmentation 0.3737480189682035 1.3335498855450376 0.1823514162174508 1.0 0.5599319608298952 82 P51812,Q9UG56,Q13432,Q8NHS3,Q9P0J0,Q8N183,O76024,P03886,P51648,P21912,Q6P4Q7,P53701,Q96S66,P02545,P40939,P00403 16 +Abnormality of bone mineral density 0.3438421448851487 1.3316219916120595 0.1829844346779918 1.0 0.5609337722107334 148 Q9NZJ7,Q14108,Q9HC21,P35670,P16278,Q9H490,P12235,Q5H8A4,Q9NWM8,O75431,O95202,Q15392,P04062,O43292,Q13510,P54802,P07602,Q9HC07,Q13126,O75844,Q9Y4P3,Q14739,P02545,Q9Y375 24 +Prolonged partial thromboplastin time 0.7013735644542525 1.3307876033042692 0.1832589081058357 1.0 0.5609337722107334 6 P28288,P38435 2 +Submucous cleft of soft and hard palate 0.4561612285749473 1.3300686515768012 0.1834956530507485 1.0 0.5609337722107334 26 O43505,O75844,P49589,Q15392,P02545 5 +Onion bulb formation 0.5878278217479318 1.3294502363854148 0.1836994733322998 1.0 0.5609337722107334 9 Q9NR77,Q8TB36,O95140,P02545 4 +Abnormality of acid base homeostasis 0.332573334640878 1.3290256947689532 0.1838394928613249 1.0 0.5609337722107334 182 Q8NI60,Q10713,Q9HC21,Q86VD7,P01889,Q9NVI7,Q9BUB7,P13073,P23786,Q6P4A7,P12235,O14949,O43676,Q9Y6M9,P08574,O14678,Q16134,Q70HW3,Q8N183,Q96I36,P21912,Q9NWS8,Q5XKP0,P51970,O96000,P82930,Q86Y39,Q9BWD1,P03886,O75380,Q9UJS0,P00403,P49748,P22695,Q9P0J0,Q9H078,Q9UBX3,P40939,Q9Y375,Q9NPL8 40 +Angiokeratoma 0.7424913631293948 1.3285091175430734 0.1840099735523339 1.0 0.5609337722107334 3 P16278 1 +Abnormal circulating citrulline concentration 0.7453260606650195 1.3272582585245538 0.184423266625572 1.0 0.5609337722107334 4 Q9UJS0,P03886 2 +Increased circulating antibody level 0.4902248514448156 1.325831559177845 0.1848954969870033 1.0 0.5609337722107334 19 Q14108,P04062 2 +Brain imaging abnormality 0.4110783318905077 1.3252945389095665 0.1850734795874633 1.0 0.5611091403856274 38 Q9NZJ7,P07602,P03886,P21912,Q9BT22 5 +Entropion 0.5757797484047161 1.3212027130318968 0.1864337819541615 1.0 0.5643421682101719 10 O75844,P02545 2 +Calcific stippling 0.7397414277684125 1.3172316370401538 0.1877609922865759 1.0 0.5670236765883846 3 P51659,P50542 2 +Limb girdle muscular dystrophy 0.5848444183637908 1.3143686607211944 0.1887221715354725 1.0 0.5687243417028632 9 P50402,Q9BTV4,P02545 3 +Ventricular preexcitation 0.6526970260157017 1.3127053193930287 0.1892822644705361 1.0 0.5692201570094387 7 P13473,P03886,P00403 3 +Partial agenesis of the corpus callosum 0.5290892177647751 1.312019516472921 0.1895135496290114 1.0 0.5692201570094387 14 Q9HC21,O60508,Q15392 3 +Heparan sulfate excretion in urine 0.7165410736113327 1.3112995292308238 0.1897565873844668 1.0 0.5692201570094387 5 P54802,P08236 2 +Gastrostomy tube feeding in infancy 0.4090926546610859 1.308268211028948 0.1907823533358075 1.0 0.5717347931481933 36 O15121,O14656,Q01105,Q9H490,P37268,Q99720 6 +Proximal muscle weakness in upper limbs 0.5037668582133759 1.3002092524887665 0.1935292603168379 1.0 0.5781113988607269 17 P50402,O14908,P07196,O95140,P02545,Q9BTV4,P36551 7 +Nephrotic syndrome 0.4346537095628478 1.2992378946565053 0.1938623004192288 1.0 0.5784631877418565 30 Q8NCH0,Q9BT22,Q14108,O95470 4 +Short lingual frenulum 0.713051132309305 1.296761314822965 0.1947133250941488 1.0 0.5786798051842317 5 O75844 1 +Neonatal hypoglycemia 0.5494583812953717 1.2967507963763971 0.1947169453729698 1.0 0.5786798051842317 12 O43772,P40939 2 +Pseudoepiphyses 0.7129662911582868 1.2964078520645197 0.1948350082993386 1.0 0.5786798051842317 5 P51812 1 +Pseudoepiphyses of hand bones 0.7129662911582868 1.2964078520645197 0.1948350082993386 1.0 0.5786798051842317 5 P51812 1 +Breech presentation 0.6054761598753648 1.2945784227804125 0.1954656998002768 1.0 0.5798153445790931 8 Q9UBM7,Q969X5,O60313 3 +Thickened skin 0.3472516750684182 1.2931090394120832 0.1959733491852273 1.0 0.5804351942312624 113 P16278,P56589,Q06136,P48449,P50402,Q9NWM8,P09493,O75431,P21912,Q9BTV4,P40855,P16615,O75381,P04062,Q9H488,Q14574,P51648,O75352,P42167,O75844,Q15800,Q14739,O95470,P02545,O15269,P00813 26 +Abnormal autonomic nervous system physiology 0.4074835329021297 1.2928943202613823 0.1960476121873422 1.0 0.5804351942312624 37 Q9NZJ7,P20700,P07602,P42892,O43681,P04062,O76024,Q96RL7 8 +Cerebellar atrophy 0.3423000732632773 1.292432730479107 0.1962073279477434 1.0 0.5805326390999648 145 Q8NI60,Q14108,Q10713,Q9NVI7,P49589,P13073,Q9H490,P12235,Q5H8A4,Q8N766,Q5BJH7,Q96CU9,O75503,O15121,Q5XKP0,P51970,Q92581,Q6DKK2,P51572,O43292,Q9BT22,O60313,P41440,P46977,Q96T60,Q8NHS3,Q9H078,Q9Y320,O14773,Q92643,Q8IV08 31 +Desquamation of skin soon after birth 0.7365504882840372 1.2916738641511982 0.1964701122225454 1.0 0.5805326390999648 4 P04062 1 +Cardiac arrest 0.4185546314791246 1.2911444485263857 0.1966535936875353 1.0 0.5805326390999648 33 P50402,P49748,P01889,O43772,P04062,Q9Y4P3,P02545,Q9BTV4 8 +Emg abnormality 0.3666017152372502 1.290877623066752 0.1967461158895465 1.0 0.5805326390999648 84 Q9NZJ7,Q8NI60,P53007,P13473,P12235,Q96RL7,P50402,P09493,O43681,O95140,Q8TB36,Q9Y6B6,Q9BTV4,P22626,Q969X5,O14773,Q13510,O43819,O60313,P42167,Q9NR77,P07602,P02545,O15269 24 +Asymmetric septal hypertrophy 0.7329192294397919 1.2892552581164012 0.1973093600542537 1.0 0.5805326390999648 3 P54802 1 +Increased skull ossification 0.7329192294397917 1.2892552581163998 0.1973093600542541 1.0 0.5805326390999648 3 P54802 1 +Progressive peripheral neuropathy 0.7358555688531954 1.2888557513583463 0.197448239642481 1.0 0.5805326390999648 4 Q9NZJ7,P07602 2 +Biliary tract neoplasm 0.7358555688531954 1.2888557513583463 0.197448239642481 1.0 0.5805326390999648 4 Q9NZJ7,P07602 2 +Neoplasm of the gallbladder 0.7358555688531954 1.2888557513583463 0.197448239642481 1.0 0.5805326390999648 4 Q9NZJ7,P07602 2 +Dry hair 0.7324339516582383 1.2872654156095582 0.1980017935377303 1.0 0.5815729534167388 3 P46778,Q9Y276 2 +Abnormal saccadic eye movements 0.4459144545875018 1.2828392014289658 0.1995484169224548 1.0 0.5851539338603108 27 Q10713,Q96T60,P04062,O95140,Q8WWI5,O14773,O43819,Q8IV08,Q96RL7 9 +Rapidly progressive 0.5575227864209343 1.2811762867371894 0.200131753286445 1.0 0.586207751627611 11 Q8NHS3,Q14108,Q8TB36 3 +Generalized onset motor seizure 0.398823883644991 1.2802334392487178 0.2004630487901126 1.0 0.5862115203864884 58 Q9NZJ7,P07602,Q8NHS3,P04062,Q01105,P21912,P03886,P16278,Q13510,Q96N66 10 +Spinal rigidity 0.5160109805260578 1.2783187238199836 0.2011370685228808 1.0 0.5862115203864884 15 P50402,Q5JTV8,Q9BTV4,P02545 4 +Patchy changes of bone mineral density 0.729967982978458 1.2771544789642233 0.2015477144020208 1.0 0.5862115203864884 3 Q14739 1 +Biliary cirrhosis 0.6448471274252716 1.2770952306658692 0.2015686284641087 1.0 0.5862115203864884 7 P09601 1 +Frontal balding 0.7299044406970245 1.2768939576262737 0.2016396876720283 1.0 0.5862115203864884 3 O60828,P04150 2 +Impacted tooth 0.7294281831289304 1.274941341380604 0.202330004898007 1.0 0.5874868114855689 3 O75844 1 +Thin clavicles 0.7294281831289304 1.274941341380604 0.202330004898007 1.0 0.5874868114855689 3 O75844 1 +Peptic ulcer 0.5338398493982898 1.2724322040955445 0.2032195979159956 1.0 0.5889710134511382 13 O76024,P04062,Q9Y4P3 3 +Redundant skin 0.4556789265955492 1.270080806988389 0.2040558475568878 1.0 0.5903684927760051 24 Q8NCH0,P51812,O96000,Q9Y4P3,P38435 5 +Pili torti 0.7278791117881968 1.2685905989443482 0.2045871190391199 1.0 0.5914657949186694 3 P02545 1 +Paraparesis 0.4471845185367461 1.2618313604011169 0.2070094750423179 1.0 0.5966217524522113 26 Q8WVX9,P04062,Q6DKK2,P35637,P21912,Q13510,Q5XKP0 7 +Nonimmune hydrops fetalis 0.4299555577597239 1.2609379181459317 0.2073312153646389 1.0 0.5971804099552741 30 P10619,P04062,Q14739,P61313,Q9BT22 5 +Limited elbow movement 0.403921071437701 1.2600180763894762 0.2076628413980681 1.0 0.5976901381915231 38 P50402,Q7LGA3,O14656,Q7RTS9,Q969X5,P02545,P37268,P23786,Q9BTV4,P16435 10 +2 3 toe syndactyly 0.403861165337604 1.259463523376892 0.2078629574824246 1.0 0.5976901381915231 39 O43924,P37268,P51812 3 +Hypoplastic heart 0.7256328256288342 1.2593824593278655 0.2078922219796601 1.0 0.5976901381915231 3 O60826 1 +Osteolysis involving bones of the upper limbs 0.5736303768536153 1.2575952783889115 0.2085381618189905 1.0 0.5984417194424504 9 O75844,P02545 2 +Aplasia hypoplasia involving the vertebral column 0.4885476775434379 1.2568486913322492 0.2088084307032791 1.0 0.5988492401434953 18 Q8TAA9,Q7RTS9,Q96HY6,Q14739,P16278,P08236 6 +Primary adrenal insufficiency 0.5043853150132285 1.254067324260889 0.2098175358931309 1.0 0.6010049540398946 16 Q13423,Q969G3,P50542,O75381,P51659,P56589,Q9Y2R9,P16435,P40855 9 +Corneal erosion 0.7268509722767176 1.2523401636783509 0.2104459396995375 1.0 0.601746328446963 4 P51648 1 +Abnormality of the intrahepatic bile duct 0.7267521806462551 1.25193957501036 0.2105918827762556 1.0 0.601746328446963 4 P02545 1 +Abnormal cns myelination 0.3389600266852655 1.2512703348313503 0.2108358647108508 1.0 0.6020750167186314 147 Q9NZJ7,Q8TAD8,P49589,Q9H490,Q5H8A4,Q99720,O60508,Q5BJH7,Q96CU9,Q8WVX9,O43676,Q9Y6M9,O43681,Q8N183,Q8TB36,Q96I36,Q9Y3C6,P21912,Q9NWS8,P20700,O96000,Q86Y39,P51572,P03886,P51648,P10253,O75380,P07602,Q7LGA3,Q9P0J0,Q8TB37,P35637,Q9Y375,Q9NPL8 34 +Diminished movement 0.4644102036378149 1.250865748133783 0.2109834622257367 1.0 0.6021282305207608 22 P13473,P12235,Q2TAA5,P04062 4 +Psoriasiform dermatitis 0.7261688391588264 1.2495742178906946 0.2114551261526907 1.0 0.6027374749736952 4 Q15800,P10321 2 +Respiratory failure 0.3840974916381732 1.2459162874508598 0.2127951298644455 1.0 0.6048503572537819 70 P61916,Q9NZJ7,P07602,Q9BT22,Q9H078,Q70HW3,Q8N183,Q9BUB7,Q15165,P40939,P53701,P10253,Q13510,Q5XKP0,P23786 15 +Dyspnea 0.3460881414627368 1.2457829048649298 0.2128441072966296 1.0 0.6048503572537819 104 Q9NZJ7,P53007,P01889,Q9UHX1,P51571,P23786,P12235,Q86TI2,Q16134,Q15165,P51970,P04062,P03886,Q969X5,P10253,Q13510,O43819,P49748,Q9Y619,P07602,O75844,P35637,Q8TCJ2,Q9NX14,P53701,P02545,Q13724 27 +Stroke 0.4129812747235497 1.243009794484722 0.2138642242253776 1.0 0.6073796003091778 33 P51970,O75844,O76024,P03886,P02545,P00403 6 +Progressive visual loss 0.4519630028110828 1.2426498259116845 0.2139969005366835 1.0 0.6073869474807145 24 Q969G3,O75503,O95140,P50897,P03886,O14773,O60313 7 +Abnormal elasticity of skin 0.3901986869998893 1.2420118075494453 0.2142322055946546 1.0 0.6074374786319157 64 Q8NCH0,P51812,Q9NWM8,O96000,Q13126,Q9UHX1,P04062,O75844,Q9Y4P3,P02545,P38435 11 +Weight loss 0.3625148308252516 1.2406643864762323 0.2147297557075878 1.0 0.6074374786319157 84 Q13423,Q9NZJ7,P07602,P42892,O75844,P04062,P35670,P21912,P02545,Q06136,Q99720 11 +Macroglossia 0.4015483474813608 1.240132176805325 0.2149265093175525 1.0 0.6074406004864726 36 P21281,Q10713,Q7LGA3,Q9Y4P3,Q96S52,P04066,Q8TAD8,P21912,P10253,P16278,Q96A33 11 +Axonal degeneration regeneration 0.6793398108636145 1.2369673099648113 0.2160992190938313 1.0 0.6079268258920889 6 Q8TB36,P02545 2 +Feeding difficulties in infancy 0.32669327735063 1.2366152828527803 0.2162299433892289 1.0 0.6079268258920889 180 P14314,O43924,Q9UGP8,Q9NZJ7,Q10713,P53007,P27635,Q9UHX1,Q9NVI7,O76024,Q01105,P49589,P56589,Q9H490,P37268,Q9UBM7,P23786,Q99720,Q5BJH7,P21964,Q12959,P12694,O43681,P49711,P21912,O15121,P40855,Q92581,O75880,O75381,P10253,O43819,Q9Y619,P07602,P51812,P22695,O14656,P35637,O60826,O60313,Q13724,P40939,Q9NPL8 43 +Abnormal sweat gland morphology 0.7228524095453079 1.2361275953519657 0.2164111388456631 1.0 0.6079268258920889 4 O75844 1 +Pulmonary carcinoid tumor 0.7198797509826922 1.2358056849169246 0.2165308013404463 1.0 0.6079268258920889 3 P02545 1 +Duplication involving bones of the feet 0.462133926604321 1.2347632162510032 0.2169186408934038 1.0 0.6082841647635451 22 O43924,Q10713,P21964,Q14739,Q9UBM7 5 +Neoplasm of fatty tissue 0.5583014614206078 1.2302943131139366 0.2185869131212419 1.0 0.6111709299296525 10 O00255,Q8TAA9,O95140,P21912 4 +Dystrophic fingernails 0.5680582517895677 1.2293428697255968 0.2189432804319064 1.0 0.6111709299296525 9 O75844 1 +Abnormal circulating non proteinogenic amino acid concentration 0.6339262930432683 1.2275050824573632 0.2196328127319864 1.0 0.6111709299296525 7 P05067,Q9UJS0,P03886 3 +Inappropriate crying 0.5915518386978663 1.22701676322436 0.2198162904668039 1.0 0.6111709299296525 8 P07602 1 +Capillary hemangioma 0.5913443144450161 1.226008951728084 0.2201953063822272 1.0 0.6111709299296525 8 Q9UBM7,Q9UHX1,P16435 3 +Abnormal talus morphology 0.4606411838698262 1.2241957703122115 0.2208783844047959 1.0 0.6111709299296525 22 O75844,Q9UHX1,Q9UPT5,O14656,Q969X5,P02545,P16435 7 +Patchy alopecia 0.7196094110698965 1.2229807496429104 0.221336967235104 1.0 0.6111709299296525 4 O75844 1 +Recurrent otitis media 0.4156989318165825 1.2225958642288497 0.2214823759779336 1.0 0.6111709299296525 32 Q13432,Q8N5M9,Q14739,Q9UBM7,P00813 5 +Advanced eruption of teeth 0.5462583999306285 1.2208956636424924 0.2221255265486528 1.0 0.6122115965890205 11 P02545,O75844,P51812 3 +Contractures of the joints of the lower limbs 0.3915710019428962 1.2206106743853546 0.2222334628212574 1.0 0.6122115965890205 60 Q5JTV8,Q86XL3,Q9HC21,P27635,P37268,O75477,P23786,Q99720,P50402,Q8IWS0,P21912,Q9BTV4,Q8N2K0,Q969X5,Q8IZA0,O60313,Q7LGA3,P35637,P02545 19 +Wide cranial sutures 0.5902222485475532 1.2205594397065953 0.2222528713254208 1.0 0.6122115965890205 8 O75844 1 +Abnormality of the bladder 0.3401915667662543 1.2156198068068922 0.2241297854228185 1.0 0.6155658636112588 133 Q86XL3,Q9NZJ7,P01889,Q9UHX1,Q8TAA9,O76024,P56589,P12235,Q99720,Q8NCH0,Q969G3,P21964,Q8WVX9,Q9NWM8,O43681,P21912,Q92581,P20700,P22626,P04062,Q92796,Q9UJS0,P16435,Q9NR77,P07602,P51812,Q9Y4P3,P35637,P07196 29 +Genetic anticipation 0.6307951671817875 1.2150195283233656 0.2243586433473401 1.0 0.6156307252502202 2 P54886 1 +B lymphocytopenia 0.5890501351473914 1.2148662401660573 0.2244171116675679 1.0 0.6156307252502202 8 Q13432 1 +Motor seizure 0.3416267896199551 1.2142201199644305 0.2246636793783667 1.0 0.6159452254947705 113 Q9NZJ7,Q01105,P13073,P16278,O60508,Q8WVX9,O75503,Q9Y3C6,P21912,Q9NZ01,Q5XKP0,Q92581,P04062,Q9UPT5,P03886,O43292,Q13510,Q2M389,P07602,Q96T60,Q8NHS3,Q9Y320,Q9UBX3,Q8WWV3,Q96N66 25 +Edema of the dorsum of feet 0.6299522337735267 1.2110825300780623 0.2258637761246038 1.0 0.6181465244582506 2 Q9Y263 1 +Edema of the dorsum of hands 0.6299522337735267 1.2110825300780623 0.2258637761246038 1.0 0.6181465244582506 2 Q9Y263 1 +Pseudoepiphyses of the metacarpals 0.7165470881965704 1.2105687636563027 0.2260607218152479 1.0 0.6183230873786717 4 P51812 1 +Insulin resistant diabetes mellitus 0.588090321374025 1.2102037786519608 0.2262007085205513 1.0 0.6183437400951135 8 O75844,P02545 2 +Vertebral hypoplasia 0.5335596478082822 1.2092285011114523 0.2265750708724041 1.0 0.6190046845542744 12 Q14739,Q8TAA9,P16278 3 +Hydrops fetalis 0.3967480442196863 1.2065924151246303 0.2275891492312491 1.0 0.6200845518248794 46 P10619,P04062,Q14739,P61313,P16278,Q13510,Q9BT22,P40939 8 +Decreased number of peripheral myelinated nerve fibers 0.4807146389813368 1.2060631715802097 0.2277931337275647 1.0 0.6200845518248794 18 Q9NR77,O95140,Q8TB36,P02545,O15269,Q96RL7 6 +Leukoencephalopathy 0.3447487639552014 1.206056135927688 0.2277958463317921 1.0 0.6200845518248794 102 Q9NZJ7,Q9UHX1,P51571,Q01105,Q9BUB7,O43676,Q9Y6M9,O75503,O43681,Q8N183,O95202,O15121,P20700,O96000,Q86Y39,P03886,O75380,P07602,P17900,O60313,Q9Y375,Q9NPL8 22 +Abnormality of neutrophil morphology 0.6719354513950815 1.2054147555627392 0.2280432279968165 1.0 0.6200845518248794 6 Q14739 1 +Decreased absent ankle reflexes 0.5218600629872746 1.2044799412663012 0.2284041303758996 1.0 0.6200845518248794 13 Q15041,O95140,O60313,P12235,Q96RL7 5 +Elevated circulating growth hormone concentration 0.7122138138559992 1.2044097809054448 0.2284312334844276 1.0 0.6200845518248794 3 O00255 1 +Pituitary prolactin cell adenoma 0.7122138138559992 1.2044097809054448 0.2284312334844276 1.0 0.6200845518248794 3 O00255 1 +Lethargy 0.3529283080370788 1.2033200132874615 0.2288525073281362 1.0 0.6208085973136096 89 Q9HC21,P23786,P12235,Q96CU9,O43676,Q9Y6M9,P12694,O14678,Q8N183,Q9NWS8,O00255,O43772,O96000,Q86Y39,P03886,P61313,O75380,Q9UJS0,P49748,Q9Y619,P18077,Q8TB37,P40939,Q96IX5,Q9Y375,Q9NPL8 26 +Progressive 0.3406754235650207 1.2027357437301522 0.2290785973083458 1.0 0.6208085973136096 110 Q03252,P28288,O75477,P12235,Q99720,Q96RL7,Q9Y6M9,Q8N183,O15121,Q5XKP0,P20700,P04062,P82930,Q13510,P54802,O60313,Q13126,Q9H078,P27544,P02545,O95470 21 +Abnormal nasal mucosa morphology 0.6904319482507534 1.202502588405687 0.2291688638691091 1.0 0.6208085973136096 5 Q13432,Q03519 2 +Abnormality of the musculature of the thigh 0.5626757585799075 1.202030835974314 0.2293515812086481 1.0 0.6208085973136096 9 P50402,O14979,Q9BTV4,P02545 4 +Abnormality of prothrombin 0.5102570146902856 1.2020019250197866 0.2293627822587227 1.0 0.6208085973136096 14 Q5XKP0,Q9UJS0,P40939,P38435 4 +Ventilator dependence with inability to wean 0.6277044113514978 1.200587049137651 0.2299114272314444 1.0 0.621728024804766 2 P38935 1 +Bifid scrotum 0.6706874252787712 1.2000962680457574 0.2301019547788896 1.0 0.621728024804766 6 P16435 1 +Abnormal gallbladder morphology 0.4127994477045369 1.1979503155152218 0.2309363599551077 1.0 0.6232611934279758 32 Q9NZJ7,P21964,P07602,P04062,Q9Y4P3,P22830,Q96A33 7 +Memory impairment 0.3969140288762665 1.196308414864896 0.231576226173285 1.0 0.624202986417618 41 Q9NZJ7,Q969G3,P07602,Q8WVX9,P01889,O43681,O96008,P03886,P05067,Q9UJS0,P00403 11 +Abnormal motor nerve conduction velocity 0.4421915611635008 1.195890028109183 0.2317394770656384 1.0 0.624202986417618 25 Q9NR77,Q96T60,O95140,Q8TB36,P02545,O15121,Q99720 7 +Mild postnatal growth retardation 0.6265805001404835 1.1953411299766568 0.2319537762764119 1.0 0.624202986417618 2 Q9Y3E5 1 +Abnormal thyroid stimulating hormone level 0.6265805001404834 1.1953411299766568 0.2319537762764119 1.0 0.624202986417618 2 O14654 1 +Renal agenesis 0.3881974311723678 1.193499653601993 0.2326737477404039 1.0 0.625419532642456 61 Q86XL3,O43924,Q9UHX1,Q8TAA9,P61313,Q15392,Q9UBM7,P16435 8 +Abnormal b cell morphology 0.5407705722577739 1.1914843638234691 0.2334634913895705 1.0 0.6266543659168944 11 Q13432 1 +Foot dorsiflexor weakness 0.406965473025199 1.19088839457338 0.2336974011099302 1.0 0.6266543659168944 33 P05023,Q9NR77,O95140,Q8TB36,O15269,Q14739,P02545,O43819,Q99720 9 +Stiff skin 0.7087327178770819 1.1901626533970906 0.2339824687796383 1.0 0.6266543659168944 3 O75844 1 +Ankylosis 0.6871493370569982 1.188825934833606 0.2345081701932376 1.0 0.6266543659168944 5 O75844,P16435 2 +Generalized lipodystrophy 0.7109903645452913 1.1880544080522368 0.2348119748813477 1.0 0.6266543659168944 4 O75844,P02545 2 +Abnormal mitral valve physiology 0.3958894155946223 1.1867348922502288 0.2353322073574593 1.0 0.6266543659168944 41 Q8WVX9,P51812,P09493,P01889,O75844,P04062,O75431,P49711,Q9Y4P3,P53701,P02545,O43819,P40939 13 +Hypergonadotropic hypogonadism 0.4929554595714992 1.1837615057101123 0.2365074841668457 1.0 0.6288459245871314 16 P48449,Q16740 2 +Endocarditis 0.6853103293402838 1.181165026550699 0.2375371717400041 1.0 0.6308900259699715 5 P04062 1 +Abnormality of the calcaneus 0.5817501088891399 1.1793967418766949 0.2382402318974996 1.0 0.6308900259699715 8 P40939,Q14739 2 +Cyanosis 0.4765954137041143 1.1793080817971655 0.2382755212862988 1.0 0.6308900259699715 18 O43772,O75844,P51812 3 +Difficulty walking 0.355740666753687 1.1791681947396204 0.238331208063161 1.0 0.6308900259699715 85 Q969G3,Q9NR77,Q9NZJ7,P07602,Q15041,P53007,Q9HC21,Q8TB37,O43681,P35670,Q7RTS9,P35637,O43292,O14773,Q13510,O75477,Q99720 17 +Widely patent fontanelles and sutures 0.6846592674960645 1.1784530688132238 0.2386160316658983 1.0 0.6308900259699715 5 O75844 1 +Abnormal femoral neck morphology 0.3946517394220874 1.1745928917396549 0.2401576284942557 1.0 0.6331428387575833 40 P51812,P02545,O75844,O75431,Q7RTS9,P16278,Q96A33 7 +Kinetic tremor 0.3942072441326681 1.1735405860114685 0.2405790911935486 1.0 0.6338960365590736 36 Q9NZJ7,Q14108,P20700,P07602,O43681,Q9BUB7,Q9Y287 7 +Developmental cataract 0.387396177156375 1.1698050920980407 0.2420794140045259 1.0 0.6364126035963579 59 P00403,Q9NVI7,O76024,Q15800,P03886,P21912,P61313,P02545,P48449 9 +Abducens palsy 0.6824250109647414 1.169147411574863 0.242344244660726 1.0 0.6367502973105964 5 P07602 1 +Open mouth 0.3935302285331306 1.167385994102873 0.2430545246871824 1.0 0.6382283475548848 36 Q86XL3,P04062,P51812 3 +Contractures of the large joints 0.7015177065767326 1.1606579876614784 0.2457810134100506 1.0 0.641807355487431 3 P50542,O75431 2 +Delayed ossification of carpal bones 0.6189940994661363 1.1599669522258131 0.2460622615231344 1.0 0.6418238542187235 2 P36776 1 +Pyelonephritis 0.6187131216633825 1.1586581075168074 0.2465955732072862 1.0 0.6421387235386611 2 Q14697 1 +Abnormal glomerular filtration rate 0.6187131216633825 1.1586581075168074 0.2465955732072862 1.0 0.6421387235386611 2 Q14697 1 +Brachydactyly 0.3521183455525377 1.1566328655770408 0.2474223887432098 1.0 0.6432235105049948 86 O43924,P51812,Q9UHX1,Q14739,P21912,P02545,Q06136,Q9UBM7,Q92643,P16435,P48449 11 +Abnormal metacarpal morphology 0.4126379925266199 1.1562883927826535 0.2475632144736508 1.0 0.6432235105049948 31 O43924,P51812,Q14739,P16278,P16435 5 +Diffuse white matter abnormalities 0.5234605561050604 1.1535010974222375 0.2487047673869074 1.0 0.6452220447578989 12 Q96T60,Q9H270,P09471,Q3ZCQ8,P16278,O43819,O75306 7 +Abnormal arterial physiology 0.4251390965657911 1.1521403762960452 0.2492633937934525 1.0 0.6458439431862542 28 Q9NWM8,P01889,O75844,Q9Y4P3,Q14739,P02545 6 +Apnea 0.3497787604553528 1.1505249448115686 0.2499277261811776 1.0 0.6469651234320786 87 O43924,Q9NZJ7,Q10713,P07602,P51812,O43772,Q9P0J0,P04062,Q86Y39,O76024,P03886,Q96A33 12 +Visual field defect 0.3900266302619108 1.1493659923341386 0.2504050968222504 1.0 0.6473651146528722 49 Q969G3,Q9Y287,O75381,P01889,O00255,Q8NHS3,O95140,Q9H061,Q8WWV3,P03886,O60313,P56589,P40855,P00403 14 +Aortic valve stenosis 0.5120594956742354 1.148773844263935 0.2506492472483304 1.0 0.6476377063654979 13 O75844,P04062,O60826,P16278,P02545 5 +Dystonia 0.3214981904027066 1.147994543752285 0.2509708162884219 1.0 0.6481099232580984 180 Q9NZJ7,Q8NI60,Q86VD7,P35670,O15118,Q01105,P49589,P16278,Q99720,Q96RL7,O14949,Q8N766,Q5BJH7,O60508,Q96CU9,P82663,O43681,Q8N183,Q9NZ01,O15121,Q92581,Q9NQZ5,P04062,Q6DKK2,P82930,P51572,P03886,P61916,P07602,Q96T60,Q9P0J0,O14656,P35637,P17900,Q96N66 35 +Vitiligo 0.6154505555725327 1.1435498992792097 0.2528103493991074 1.0 0.6507009489219583 7 P03886,P00403 2 +Osteopenia 0.3722610476677895 1.1409137745912912 0.2539058066626611 1.0 0.652800777151963 72 Q9NZJ7,Q14108,P07602,Q9NWM8,Q13126,O75844,P04062,O43292,P02545 9 +Sudden loss of visual acuity 0.6964807295246197 1.1400830603787486 0.2542516985160272 1.0 0.6533256681746508 3 O00255 1 +Abnormal abdomen morphology 0.3288093120220803 1.132624753272107 0.25737186911909 1.0 0.6588098996255655 239 Q9UGP8,Q14108,Q9NZJ7,P10619,Q10713,P53007,Q9HC21,P28288,P01889,Q9NVI7,P35670,Q9H0U3,O15118,Q9BUB7,P16278,P56589,Q01844,P23786,Q96RL7,Q96CU9,Q07021,P21964,O43676,Q9Y6M9,Q16134,O95140,P33991,P14927,P04066,O75431,Q8N183,Q96HY6,Q96I36,Q9NWS8,Q15392,P00374,Q9Y4L1,Q9Y285,Q96A33,P40855,P08236,O75880,P09601,P51798,O75381,O43772,O96000,P04062,Q86Y39,Q9NZ08,Q6PGP7,P03886,P10253,Q13510,O75380,Q9BT22,Q9UJS0,P54802,P61916,P49748,Q9Y619,P07602,Q9HC07,Q8TB37,P40939,Q9Y375,Q14739,Q9NX14,P02545,Q13724,P14314,P00813,Q9NPL8 73 +Inflammation of the large intestine 0.5082441599306279 1.127067851172546 0.2597137946009293 1.0 0.6610159901753933 13 P49748,P08183,Q6PGP7 3 +Abnormality of the posterior pituitary 0.5708669347178336 1.1264974526025695 0.2599550182338748 1.0 0.6610729739291729 8 O76024,Q9UHX1 2 +Glomerular deposits 0.611407698791789 1.124665962406291 0.2607306104007638 1.0 0.6616218554338945 2 P52565 1 +Reduced tendon reflexes 0.3207282167658639 1.1235529663509003 0.2612027187081931 1.0 0.6616218554338945 183 Q9NZJ7,Q10713,Q15041,P53007,Q9HC21,Q8TAA9,Q8TAD8,P56589,O75477,P12235,Q99720,Q5H8A4,Q96RL7,Q8N766,P50402,O43681,O95140,Q8TB36,Q9Y6B6,Q9NWS8,Q9BTV4,P40855,O75381,P04062,P03886,Q969X5,P10253,Q13510,Q9BT22,P54802,O60313,P05023,P41440,Q9NR77,P07602,O43505,Q96T60,P35637,P02545,O15269,P40939 41 +Incomplete penetrance 0.4131416437464657 1.123149848195798 0.2613738582341089 1.0 0.6616218554338945 30 Q969G3,O95140,O14656,P03886,P21912,O60313 6 +Pulmonary hypoplasia 0.4173624127869356 1.1227673901020263 0.2615362983972744 1.0 0.6616218554338945 29 O96000,O75844,Q16134,Q8TAA9,Q14739,P02545,Q9UBM7 7 +Loss of eyelashes 0.6920954089716772 1.1221880432432398 0.2617824953662002 1.0 0.6616218554338945 3 O75844 1 +Limb girdle muscle weakness 0.4289225651353998 1.1221775895658883 0.2617869391904659 1.0 0.6616218554338945 26 Q9NZJ7,P07602,P53007,Q13126,O60313,P02545,P12235 7 +Weak cry 0.5276944859556997 1.121328274274878 0.2621481545411837 1.0 0.6616218554338945 11 Q13510,O60313 2 +Postaxial polydactyly 0.4550733674771042 1.119018813967761 0.263132112786411 1.0 0.6616773652496623 20 O43924,Q9UM00,Q10713,Q14739 4 +Abnormal spermatogenesis 0.475064467137001 1.1189381180723894 0.2631665397456031 1.0 0.6616773652496623 17 P04062,P16435 2 +Acquired abnormal hair pattern 0.6099343771671475 1.1184876655750122 0.2633587715598429 1.0 0.6616773652496623 7 O75844 1 +Unusual infection by anatomical site 0.474693522765622 1.116587307950489 0.2641708208484077 1.0 0.6622153830660329 17 Q9BUB7,Q14739,Q8TAA9 3 +Abnormal enzyme coenzyme activity 0.3225346506257575 1.1137639591586366 0.2653804623991749 1.0 0.6635346246303716 195 Q9NZJ7,P10619,Q10713,P01889,P35670,O15118,P16278,P23786,P12235,Q96RL7,Q8N511,P08574,O14678,O75431,Q5XKP0,Q96A33,Q2TAA5,O43772,P04062,P03886,P61313,P10253,Q13510,Q9UJS0,P61916,P41440,P49748,P07602,O43505,Q9HC07,Q9H078,P40939,Q14739,Q92643,P00813 35 +Adult onset 0.3685279848313533 1.1126543758867449 0.2658568973157651 1.0 0.6641443839311436 73 Q9UGP8,Q9NZJ7,Q9H0U3,O76024,O15118,P12235,Q969G3,P21912,Q9BTV4,P20700,Q9NQZ5,P04062,P41440,P07602,Q96T60,O14979,P02545,P38435,P14314,Q8IV08 20 +Urticaria 0.4941857966550264 1.1077746109156392 0.2679591675494857 1.0 0.6658336100524473 14 P51648 1 +Oligosacchariduria 0.6675181789340414 1.1071165903125055 0.2682435235610256 1.0 0.6661856444183132 5 P10253,P16278 2 +Hypopigmented skin patches 0.4111022021814355 1.1063709348621944 0.2685660004285997 1.0 0.6666319276986347 30 Q9NZJ7,P21964,P07602,P21912,Q8IZA0 5 +Hyperkinetic movements 0.4938683520151238 1.1059114727349897 0.268764838540299 1.0 0.6667710048590095 14 Q9NZJ7,P07602,Q96RL7,Q92581 4 +Shallow acetabular fossae 0.6071930317504851 1.1050917823865123 0.2691198209983936 1.0 0.6672971026242697 2 Q9NUQ7 1 +Intestinal hypoplasia 0.690040999127165 1.1033178069055494 0.2698891763075339 1.0 0.6684947290078919 4 O75844 1 +J shaped sella turcica 0.6898861994051313 1.102692828275449 0.270160582277172 1.0 0.6688121731983648 4 O75431 1 +Coronal craniosynostosis 0.6658231010058091 1.1000711329240418 0.271301130180577 1.0 0.6709242461933866 5 Q6NUK1,P16435 2 +Poor wound healing 0.6468609717943945 1.0986145563603549 0.2719362257322668 1.0 0.6721388236865822 6 P04062 1 +Abnormality of the dorsal column of the spinal cord 0.6860595840359796 1.0975892378026584 0.2723838944096837 1.0 0.6728891021157742 3 P54886,Q8WVX9 2 +Fasciculations 0.3860263628366017 1.0956032952952732 0.2732524189923044 1.0 0.6746777071787782 38 Q9NZJ7,P07602,P22626,P35637,Q969X5,Q9NWS8,Q13510,O43819 8 +Hypoglycemic coma 0.5415710124843854 1.0948277704592893 0.2735920976779304 1.0 0.6749058769579298 9 Q13423,P40939 2 +Pelvic kidney 0.5639950216768936 1.0930983732256674 0.2743506101771396 1.0 0.6749058769579298 8 Q9UHX1 1 +Papilloma 0.5319948675620265 1.0930487570891558 0.2743723929593673 1.0 0.6749058769579298 10 P21912 1 +Thoracic scoliosis 0.5020428391536494 1.091772480589977 0.2749331178044503 1.0 0.6749058769579298 13 O75477,O75844,Q9UHX1,P02545 4 +Lymphopenia 0.4175321704428686 1.0917684610978546 0.274934884980506 1.0 0.6749058769579298 28 Q13432,O95470,P00813 3 +Pain 0.3194237291138745 1.0901742524691118 0.2756363928737295 1.0 0.6759171839955059 186 Q9NZJ7,Q14108,Q03252,P01889,Q8TAA9,P35670,O75477,Q01844,P23786,P12235,P50402,Q969G3,P21964,Q8WVX9,O95140,Q70HW3,Q96HY6,Q15165,P21912,Q9BTV4,P20700,P22626,O00255,P04062,Q13510,O60313,Q13423,Q9NR77,P49748,P07602,P42892,O75844,Q9Y4P3,P35637,Q15800,Q14739,P02545,O15269,P40939 39 +Hyporeflexia of lower limbs 0.5214270188610677 1.087681654307144 0.2767356693962541 1.0 0.6771776915631067 11 Q9NR77,P40939 2 +Abnormal renal cortex morphology 0.3811293633143778 1.086765269869834 0.2771405601121834 1.0 0.6771776915631067 56 Q14108,P01889,Q16134,Q6PGP7,P21912,P03886,P02545,P00813,O95470,P00403 10 +Hyperglycemia 0.6436656542466326 1.0850221857172402 0.2779118292590565 1.0 0.6775113499422181 6 O75844 1 +Intestinal malrotation 0.4084958199103096 1.08491035231582 0.2779613624526045 1.0 0.6775113499422181 30 Q8NCH0,P21964,Q14739,Q15392,Q9UBM7 5 +Prominent ear helix 0.6854422652094478 1.0847603994672808 0.2780277889246711 1.0 0.6775113499422181 4 O75844 1 +Absence of pubertal development 0.6847321637705843 1.0818966863699873 0.2792984374363785 1.0 0.6786757679990358 4 O75844 1 +Spinal muscular atrophy 0.489078661581307 1.077794847923011 0.2811253192714422 1.0 0.6817383640611661 14 Q99720 1 +Abnormality of macular pigmentation 0.6836608070522374 1.0775770454053304 0.2812225506921837 1.0 0.6817383640611661 4 Q9UM00 1 +Arthralgia 0.3837115898374317 1.075814916403122 0.2820100398223513 1.0 0.6832926185420645 37 Q03252,P01889,P35670,Q9Y4P3,Q96HY6,Q15800,P02545,Q13510 8 +Abnormality of peripheral nerves 0.3806617862223377 1.0725261376586253 0.2834837805036101 1.0 0.6861422500415194 54 Q9NZJ7,Q8N2K0,Q9NR77,Q9Y619,P07602,Q96T60,O43681,O95140,Q8TB36,P02545,O15121,O15269,Q99720,Q96RL7 14 +Restlessness 0.3829959230125382 1.071364047388807 0.284005771914918 1.0 0.686604785090789 36 P42892,P04062,O96008,P35637,Q15165,Q9UJS0,P48449 7 +Feeding difficulties 0.3077386652192192 1.0709812096637337 0.2841778785839322 1.0 0.686604785090789 375 O43924,P53007,Q8TAD8,P49589,P56589,P37268,Q99720,Q969G3,Q96CU9,O43676,P12694,P49711,Q15392,P40855,O75880,P04062,Q86Y39,P03886,Q13510,O75352,O43819,Q6UX04,Q2M389,Q9Y619,P07602,P51812,Q8TCJ2,Q9NX14,Q13724,Q96N66,P40939,P14314,Q9NZJ7,Q9UGP8,Q99797,Q9HC21,Q9UHX1,Q01105,Q5H8A4,Q5BJH7,Q9Y6M9,P21912,P00374,Q5XKP0,Q96A33,Q9UM00,P46977,P02545,Q10713,Q9NVI7,O76024,P16278,Q9H490,Q9UBM7,P23786,P21964,Q12959,Q9NZ01,O15121,Q2TAA5,O96000,P49748,Q7LGA3,Q9H078,P53701,O60313,Q9Y375,Q9NPL8,P55795,P51571,Q6NUK1,O14678,O43681,Q8N183,Q9NWS8,Q92581,P20700,O75381,P82930,Q969X5,P10253,O75380,P22695,Q8TB37,O14656,P35637,O60826 87 +Positive romberg sign 0.5988178729000251 1.0680146780126836 0.2855138908420476 1.0 0.6889221479801138 7 P41440,O95140,Q8IV08 3 +Abnormal circulating sulfur amino acid concentration 0.5358831108019608 1.0659317643179669 0.2864544887565179 1.0 0.6905486551680271 9 O14678,Q9UJS0,Q6PGP7 3 +Abnormal serum insulin like growth factor 1 level 0.6781801305820345 1.065539908881503 0.2866316756726572 1.0 0.6905486551680271 3 O00255 1 +Adrenocorticotropin deficient adrenal insufficiency 0.6781801305820345 1.065539908881503 0.2866316756726572 1.0 0.6905486551680271 3 O00255 1 +Calvarial skull defect 0.5357316563070148 1.0651624567941131 0.2868024197337564 1.0 0.6906036605141356 9 Q14739,Q5H8A4 2 +Abnormal lung development 0.3805873537491367 1.0642370214824457 0.2872213397957468 1.0 0.6908997606936331 52 P21964,O96000,O75844,Q9UHX1,Q8TAA9,Q16134,O95202,Q14739,P02545,Q9UBM7,Q5H8A4 11 +Abnormal bone structure 0.3190639976789662 1.06319511451017 0.2876934774846991 1.0 0.6916791175983832 192 Q86XL3,Q9NZJ7,Q14108,Q9HC21,P35670,P16278,Q6NUK1,Q9H490,Q9UBM7,P12235,Q5H8A4,Q9UG56,Q9NWM8,O75431,P21912,O00116,Q15392,O95202,P04062,Q7RTS9,O43292,Q13510,P54802,P07602,Q9HC07,Q13126,O75844,Q9Y4P3,Q14739,P02545,Q9Y375,P38435 32 +Abnormal midbrain morphology 0.5350829693227491 1.0618675676375822 0.2882958103909361 1.0 0.6927705294468763 9 O43924,P04062 2 +Ovarian cyst 0.4726416925154616 1.0584124512682334 0.2898674453099874 1.0 0.6955997681012649 16 P02545,P21912,P16435,Q9Y4P3 4 +Abnormality of the gingiva 0.3803036598442351 1.0583362811849215 0.2899021577899705 1.0 0.6955997681012649 51 Q8N766,Q14108,P20700,P49257,P04062,Q9UM00,Q9Y4P3,Q15392,Q14739,P16278,Q9UBM7,P08236 12 +Decreased plasma carnitine 0.5061691279862752 1.0579699866363377 0.2900691258284777 1.0 0.6955997681012649 12 P40939,O43772,P23786 3 +Hammertoe 0.4371780894674791 1.0574396708201943 0.2903109743545795 1.0 0.695822350750273 22 Q9NR77,O95140,O14656,Q8TB36,Q9UBM7,Q99720 6 +Leukodystrophy 0.3742980290124175 1.0550458544486463 0.2914043536690254 1.0 0.6973448708538672 62 Q9NZJ7,P20700,P07602,O43676,Q9Y6M9,O96000,O43681,Q9P0J0,Q86Y39,Q8N183,P21912,P03886,O75380,Q9Y375,Q9NPL8 15 +Limb dystonia 0.4495766228319551 1.054419360488625 0.2916909622186125 1.0 0.6973448708538672 19 Q5BJH7,Q99720 2 +Thoracic kyphoscoliosis 0.6364645067094856 1.05441494702726 0.2916929819613627 1.0 0.6973448708538672 6 O75844 1 +Progressive hearing impairment 0.4717653376871092 1.052998195473304 0.2923418191234366 1.0 0.6981190527317076 16 O76024,P03886,P00403 3 +Dysphonia 0.3859070041979497 1.0522673351878644 0.2926769137951159 1.0 0.6981190527317076 34 P20700,P53007,Q6DKK2,O95140,Q9Y4P3,P21912,Q13510,Q96RL7 8 +Narrow nose 0.6358609720223798 1.0518515461855051 0.2928676653917599 1.0 0.6981190527317076 6 P49589 1 +Vertical supranuclear gaze palsy 0.5146192422440385 1.0511348179462896 0.2931966748298633 1.0 0.6981190527317076 11 O15118,Q96RL7 2 +Malrotation of small bowel 0.6768632423904621 1.0501982510953316 0.2936269734662855 1.0 0.6981190527317076 4 Q8NCH0 1 +Pruritus 0.4195158125652342 1.049904983825605 0.2937617999741002 1.0 0.6981190527317076 26 P16615,P35670,Q14739,P22830,Q96A33 5 +Abnormal nerve conduction velocity 0.3798594788685208 1.0491917770867574 0.2940898624556398 1.0 0.6981190527317076 49 Q9NZJ7,Q8N2K0,Q9NR77,Q9Y619,P07602,Q96T60,O43681,O95140,Q8TB36,P02545,O15121,O15269,Q99720 13 +Episodic tachypnea 0.5548258604620344 1.0485591862063042 0.2943810485772311 1.0 0.6984070710401891 8 P49748,O43924,Q10713 3 +Tinnitus 0.477411934966336 1.0464764056999578 0.2953411327498378 1.0 0.6999734765527884 15 O95140,Q969G3,P21912,Q9NR77 4 +Atrophy degeneration affecting the cerebrum 0.3245300240621604 1.0431385616752475 0.296884123298222 1.0 0.70220464624083 263 O43924,Q9NZJ7,Q10713,Q9UHX1,O76024,Q01105,Q9BUB7,P49589,P13073,P16278,Q9H490,Q5H8A4,Q96RL7,Q5BJH7,O14678,O75503,O96008,P50897,Q9NZ01,Q9NWS8,P00374,Q96A33,P51970,Q92581,P20700,Q2TAA5,P04062,Q6DKK2,P03886,Q9BT22,Q9UM00,P00403,O60313,P07602,P51812,Q7LGA3,Q8NHS3,Q9H078,Q9Y320,Q9Y4P3,P17900,O14773,Q96N66 43 +Bradykinesia 0.4249461981741539 1.0421104542797828 0.2973604722271856 1.0 0.7022829304900794 24 Q96IX5,P12235,Q96RL7,P04062 4 +Failure to thrive 0.319340097642466 1.0394896891738388 0.2985770509294969 1.0 0.7022829304900794 321 O43924,Q9NZJ7,P55795,P51571,P35670,Q9BUB7,P49589,P13073,Q6NUK1,P37268,Q9UBM7,P12235,Q5H8A4,P21964,O43676,Q9Y6M9,Q8N183,P21912,O00116,Q15392,O95202,Q5XKP0,O15121,P51970,P20700,Q2TAA5,O75381,O96000,P04062,Q86Y39,Q6PGP7,Q7RTS9,P51572,P03886,P10253,Q13510,O75380,Q9UJS0,P00403,Q13423,P07602,P46977,P42892,Q9HC07,Q96T60,O75844,Q9P0J0,Q8N5M9,Q9Y4P3,Q15800,Q9Y375,Q14739,P53701,P02545,P40939,P00813,Q9NPL8 57 +Primitive reflex 0.5924278431045462 1.0390346402083108 0.2987886261852313 1.0 0.7022829304900794 7 P40939 1 +Delayed menarche 0.632723484510558 1.0385307716348506 0.2990230168803336 1.0 0.7022829304900794 6 O75844,P02545 2 +Encephalopathy 0.328759252146631 1.0379553350375643 0.2992908498079865 1.0 0.7025585609620356 108 Q9NZJ7,P53007,Q9NVI7,Q9BUB7,P23786,O43676,Q9Y6M9,P08574,Q8N183,O43772,O96000,P04062,Q86Y39,P03886,O75380,Q9UJS0,P00403,P07602,Q8TB37,Q9H078,P40939,Q9Y375,Q9NPL8 23 +Abnormality of the metacarpal bones 0.3796419994587489 1.0352955452939618 0.3005309095948343 1.0 0.7042514315423285 39 O43924,P51812,Q7RTS9,O95202,Q14739,P16278,Q9UBM7,P16435 8 +Protrusio acetabuli 0.6706014614952265 1.03479262533586 0.3007657677054665 1.0 0.7042514315423285 3 Q96AY3,O75718 2 +Urinary incontinence 0.3781938705005405 1.0347812644438 0.3007710745296457 1.0 0.7042514315423285 50 Q9NZJ7,Q969G3,P07602,P07196,Q8WVX9,P51812,O43681,Q8TAA9,P35637,Q92796,Q99720,Q92581 12 +Narrow forehead 0.3772854570121992 1.0344688574027234 0.3009170284701103 1.0 0.7042514315423285 53 Q7LGA3,Q9UHX1,Q9UM00,Q9UBM7,P49589,O43292,Q9H490,Q96A33 8 +Severe short stature 0.4171834110886507 1.0319598509616947 0.3020909261339024 1.0 0.7057734970151377 26 P10619,Q9Y619,Q7RTS9,Q96HY6,P21912,P53701,Q15392,Q9NX14,P16278 9 +Abnormal oral physiology 0.3734540120896007 1.0313331769692322 0.3023846052826773 1.0 0.7057734970151377 60 Q9NR77,P55795,P51812,P01889,P35670,P35637,Q15165,Q14739,Q96RL7,Q92581 10 +Limitation of movement at ankles 0.6720611033143248 1.0308892442031723 0.3025927610345882 1.0 0.7057734970151377 4 O75844 1 +Hyperkeratosis 0.3695897286858289 1.0304971721116785 0.3027766790578969 1.0 0.7057734970151377 65 P42167,P16615,Q9NWM8,O75844,P04062,P21912,P51648,Q06136 8 +Symptomatic seizures 0.5510200826300352 1.0300868355639894 0.3029692443954905 1.0 0.7058699611190347 8 Q16836,Q13423,P40939 3 +Corneal dystrophy 0.6480432477270606 1.0263194704401588 0.3047410225869473 1.0 0.7078785246061976 5 P12235 1 +Hyporeflexia 0.3278200415637243 1.0253720017422303 0.3051876938131357 1.0 0.7083631648571364 130 Q9NZJ7,Q10713,P53007,Q9HC21,Q8TAD8,P12235,Q5H8A4,Q99720,Q96RL7,Q8N766,O43681,O95140,Q8TB36,Q9NWS8,P04062,P03886,P54802,P05023,P41440,Q9NR77,P07602,O43505,Q96T60,P35637,P02545,O15269,P40939 27 +Chordee 0.589290825165918 1.0248196871557735 0.3054482753177339 1.0 0.7083631648571364 7 P49589,P16435 2 +Central hypoventilation 0.5892218077551312 1.0245070452776983 0.3055958448568787 1.0 0.7083631648571364 7 Q8N183,O43819,O75306 3 +Abnormal circulating fatty acid anion concentration 0.4901213337896954 1.0239035762385038 0.305880820902404 1.0 0.7083631648571364 13 P40939,O43772,P23786 3 +Lower limb hypertonia 0.5187309176882018 1.0238230186843986 0.3059188759034124 1.0 0.7083631648571364 10 Q14739 1 +Progressive gait ataxia 0.5091310984155644 1.0216816680839826 0.3069315902823284 1.0 0.7091932712243041 11 P07602,O14773 2 +Deformed sella turcica 0.6284474765246819 1.020391217318369 0.3075429575116861 1.0 0.7094983059339918 6 Q7RTS9,O75431 2 +Adducted thumb 0.4085544617235101 1.0203431024955836 0.3075657680896122 1.0 0.7094983059339918 28 Q86XL3,Q8NCH0,P42892,Q9Y4P3,Q92581 5 +Hypointensity of cerebral white matter on mri 0.6279687871481351 1.0183616996323936 0.308506096685754 1.0 0.7109649385122337 6 P07602 1 +Limb myoclonus 0.6268581913134709 1.013654017353767 0.3107478726537604 1.0 0.7140966637801816 6 Q13510 1 +Increased total bilirubin 0.6672708503178911 1.0116583670664157 0.3117014281295409 1.0 0.7143624998520103 4 P14314,P23786 2 +Cirrhosis 0.3770746841272702 1.01138647597186 0.3118314914537641 1.0 0.7143624998520103 39 Q14108,Q10713,P04062,P35670,Q14739,P22830 6 +Abnormal conjunctiva morphology 0.4144543273245981 1.01095290544408 0.312038970645252 1.0 0.7143624998520103 26 Q13510,Q14739,P10619,P21912 4 +Polycystic liver disease 0.6668921973629669 1.010139614019237 0.3124284053754134 1.0 0.7143624998520103 4 P14314 1 +Impaired visuospatial constructive cognition 0.5465773184800933 1.008537278452898 0.3131966008098197 1.0 0.715418262808732 8 P03886,P00403 2 +Hyperextensibility of the finger joints 0.6434775573478693 1.0074355058788798 0.3137255360248625 1.0 0.7159259666178315 5 P51812 1 +Abnormality of hand joint mobility 0.6434775573478693 1.0074355058788798 0.3137255360248625 1.0 0.7159259666178315 5 P51812 1 +Hemifacial spasm 0.6660437548751768 1.006737328927909 0.3140610184945152 1.0 0.716151630728191 4 Q10713 1 +Urinary urgency 0.5240699275227979 1.005962021372535 0.3144338395683017 1.0 0.716151630728191 9 P20700,P04062 2 +Meningioma 0.5152665848059563 1.0057559918442178 0.3145329616240055 1.0 0.716151630728191 10 Q969G3,P21912,P02545 3 +Vomiting 0.3338894882745058 1.005580201219995 0.314617551800175 1.0 0.716151630728191 96 Q9NZJ7,P51571,Q9UBM7,P23786,Q96CU9,O43676,Q9Y6M9,P12694,Q16134,Q8N183,Q9Y6B6,Q2TAA5,P11117,O00255,O96000,Q86Y39,P03886,O75380,Q9UJS0,P00403,Q13423,P49748,Q9Y619,P07602,P22695,Q8TB37,P40939,Q9Y375,Q9NPL8 29 +Demyelinating peripheral neuropathy 0.4569736527470661 1.0041763442655338 0.3152936221725366 1.0 0.7167020067787603 17 P41440,Q9NR77,O15121,P03886 4 +Prominent eyelashes 0.5452876709913055 1.0022852716882371 0.3162058338536115 1.0 0.7176853886433208 8 Q969G3,P20700 2 +Abnormal cardiac test 0.4635125560613983 1.00200519077026 0.31634108584878 1.0 0.7176853886433208 16 P49748,O00255,P40939,P10253,Q16836,P12235,Q9BTV4 7 +Sparse eyelashes 0.4377885902548875 1.000786187175551 0.3169301888616989 1.0 0.718325280810472 20 Q15427,O75844,Q14574,P02545,Q9UM00,Q6UX04,P48449 7 +Skeletal dysplasia 0.3752831757557778 0.998630877444908 0.3179735365892879 1.0 0.719640544030725 46 P07237,P10619,Q15427,O75381,Q9HC07,Q7RTS9,Q96HY6,Q14739,P51648,P16278,P56589,Q6UX04,P40855 13 +Atrial arrhythmia 0.522101459987844 0.995978561417056 0.3192605618102875 1.0 0.722203276691973 9 P50402,Q9BTV4,P02545 3 +Recurrent bronchitis 0.6405136245847376 0.9951911265664224 0.3196433166558261 1.0 0.722357051876591 5 Q03519,Q03518 2 +Joint stiffness 0.3679046988767209 0.9948840098474128 0.3197926807086986 1.0 0.722357051876591 63 P50402,Q15427,P01889,O75844,Q8TAA9,O75431,O95140,Q9Y4P3,O76024,P51648,P16278,P54802,P02545,Q9BTV4,P16435 15 +Deposits immunoreactive to beta amyloid protein 0.6603648714777756 0.9934064651405652 0.3205119122058777 1.0 0.722932424197702 3 O96008 1 +Purpura 0.4279700683131391 0.9917688812674496 0.3213102810390502 1.0 0.724383245857714 22 Q8NCH0,P04062,P38435 3 +Epistaxis 0.454361307974587 0.987596516038574 0.3233502932358063 1.0 0.7276512454232273 17 P01889,P04062,P12814,P38435,Q86YV9 5 +Skeletal myopathy 0.6386574412961266 0.9875292780674026 0.3233832371499672 1.0 0.7276512454232273 5 P40939 1 +Abnormal vertebral morphology 0.3257571169338675 0.9863980694460238 0.3239378120730158 1.0 0.7285479983472597 118 Q14108,P10619,Q10713,Q9UHX1,Q8TAA9,P16278,Q6NUK1,Q9UBM7,Q5H8A4,Q8NCH0,O95202,P04062,Q7RTS9,Q9UM00,P54802,P16435,P51812,Q9Y4P3,Q14739,P00813 20 +Generalized abnormality of skin 0.3207054710162202 0.9855528287935224 0.3243525953816784 1.0 0.7291296426755206 239 Q14108,P10619,Q03252,P53007,P28288,P01889,P35670,O15118,P16278,P56589,Q06136,P37268,P22830,Q9UBM7,Q6NUK1,Q86YV9,Q8NCH0,P21964,Q15427,P49257,Q9NWM8,Q16134,O75431,P49711,P21912,P00374,P40855,O75381,O00255,O43772,P04062,Q6PGP7,Q9H488,P03886,P51648,Q8IZA0,Q9UJS0,P00403,P61916,P49748,P51812,Q13126,O75844,Q9Y4P3,O14656,Q14739,P53701,P02545,O15269,P00813,P38435 51 +Oral pharyngeal dysphagia 0.4731150421642284 0.9840761685941408 0.3250780634375894 1.0 0.7297064798990889 14 Q13510,Q01105 2 +Functional abnormality of the inner ear 0.321331661279069 0.983419315086228 0.3254011078648289 1.0 0.7300806211537174 260 Q9NZJ7,P53007,P01889,Q9H061,O76024,P56589,Q9UBM7,P12235,Q96CU9,Q8WVX9,O43676,Q9UG56,Q9NWM8,Q9Y6M9,O43681,P09493,O95140,Q8N183,P21912,O95202,Q9UBC2,Q5XKP0,P40855,Q8N2K0,P20700,Q2TAA5,O75381,O00255,O96000,P04062,Q86Y39,P51572,Q92796,P03886,Q02978,Q16740,Q13510,O75380,P00403,P42167,O60313,Q9NR77,P41440,P07602,P51812,P42892,Q7LGA3,O75844,Q8TB37,P35241,Q9Y4P3,P35637,Q9Y375,Q9NX14,O95470,P02545,Q13724,O15269,P07196,Q9NPL8 60 +Hepatic necrosis 0.5409963587610324 0.981494360668704 0.3263490140059268 1.0 0.7318556899105055 8 P40939,Q16134 2 +Proximal muscle weakness 0.3622690279871915 0.9802469085934548 0.3269642546326277 1.0 0.7321803860334478 68 Q8NI60,P53007,P13473,P35670,P12235,Q99720,P50402,O95140,Q8TB36,P21912,Q9BTV4,P22626,P10253,Q13510,O60313,Q13126,P35637,P02545,P07196 19 +Distal lower limb muscle weakness 0.4343205301489943 0.9770387186287128 0.3285499842932586 1.0 0.7347032224187976 20 Q9NR77,P53007,Q96T60,Q8IY17,O95140,P02545,P07196 7 +Premature loss of teeth 0.4817687190114655 0.9763770559284376 0.3288776472168102 1.0 0.7347032224187976 13 O75844 1 +Ankyloglossia 0.5398196474417706 0.975797047868882 0.3291650479944683 1.0 0.7347547388161945 8 O75844 1 +Chronic pulmonary obstruction 0.5779618710879251 0.973569385686725 0.3302703931423756 1.0 0.7360395789702754 7 P09601 1 +Microcytic anemia 0.5088500281230778 0.9723187519391578 0.3308919977821234 1.0 0.7360395789702754 10 Q9UBX3 1 +Duplication of hand bones 0.3664392042091436 0.9714234592668288 0.3313374511623852 1.0 0.7360395789702754 62 O43924,Q10713,P21964,Q9UHX1,Q9UM00,Q14739,P61313,Q9UBM7,Q5H8A4 9 +Cardiovascular calcification 0.5172194342201615 0.9712347754124312 0.3314313803717423 1.0 0.7360395789702754 9 O75844,P04062,P02545 3 +Aplasia hypoplasia of the 5th finger 0.4583459138317404 0.9700859517192936 0.3320036508225916 1.0 0.7362704458812617 16 Q8TAQ2,Q969G3,Q9UHX1,P13073 4 +Abnormality of temperature regulation 0.3244403262485682 0.9695575320149518 0.33226708997053 1.0 0.7362704458812617 114 Q9NR77,Q9NZJ7,P49748,P07602,Q2TAA5,P20700,Q9HC21,Q9HC07,O43772,P01889,P51572,P03886,Q14739,Q13510,Q5XKP0,P23786,P00813,P00403 18 +Recurrent fever 0.464130095159789 0.9665225816306754 0.3337827529052695 1.0 0.7371888400896555 15 Q13510 1 +Proximal muscle weakness in lower limbs 0.4243853290096353 0.966188793780578 0.3339497193063905 1.0 0.7371888400896555 22 P50402,O95140,P35670,P02545,P12235,Q9BTV4 6 +Abnormal nephron morphology 0.363580423740904 0.9652866804914108 0.3344012412921189 1.0 0.7371888400896555 65 Q14108,P01889,Q9Y4P3,P03886,P21912,P02545,P00813,P23786,O95470,P00403 10 +Hyperconvex nail 0.5375428391917345 0.9647783520960256 0.3346558409784697 1.0 0.7373799535292472 8 P42892,P51812 2 +Abnormality of the spleen 0.3231472906676184 0.9630291409407068 0.3355328994119191 1.0 0.7386153264282179 134 Q9NZJ7,Q14108,P10619,Q10713,P35670,O15118,P16278,Q96RL7,P21964,O95202,Q15392,Q96A33,P04062,Q13510,Q9BT22,P54802,P07602,Q14739,P02545,P00813 20 +Difficulty in tongue movements 0.6526296206749365 0.9622612151792458 0.3359184062148361 1.0 0.7391154753143591 3 P10253 1 +Stenosis of the external auditory canal 0.5367679470817637 0.961029806697118 0.336537181079815 1.0 0.7393252789979129 8 P16435 1 +Posterior embryotoxon 0.4355828238524933 0.9604730906409954 0.3368171678379517 1.0 0.7393252789979129 19 P21964,O75381,Q7LGA3,Q9Y4P3,P53701,P56589,P40855 7 +Abnormality of the optic nerve 0.319727055332604 0.9599653435919192 0.3370726574017799 1.0 0.7393252789979129 279 Q9NZJ7,Q9NPL8,Q10713,Q9HC21,P01889,Q9UHX1,Q9NVI7,Q9H061,O76024,Q96S66,P16278,P56589,Q9H490,P37268,Q9UBM7,Q5H8A4,Q8N766,Q969G3,Q96CU9,P21964,O43676,Q9UG56,Q9Y6M9,O43681,O95140,Q8N183,P50897,O95202,Q6P4Q7,Q5XKP0,P40855,Q8N2K0,O75381,O96000,P04062,P82930,Q86Y39,P51572,P03886,O43292,O75380,O75352,O43819,Q96TA2,P00403,P41440,P07602,O43505,P51812,Q7LGA3,Q8NHS3,Q9P0J0,Q8TB37,Q6ZXV5,O14656,Q8TCJ2,Q9Y375,Q8WWV3,Q9NX14,O60826,O60313,Q13724,P98175,P07196,P38435,Q9Y287 66 +Disproportionate short trunk short stature 0.6314286998463784 0.9577410341654432 0.3381933595524866 1.0 0.740388252593561 5 Q9UHX1,P16278 2 +Generalized hyperpigmentation 0.4778182553558844 0.9539168842688348 0.3401257161410311 1.0 0.743119779439623 13 P51648 1 +Pulmonary fibrosis 0.4308857774835239 0.9535184457072472 0.3403274548351795 1.0 0.7432127626873029 20 P09601,P04062 2 +Dermatological manifestations of systemic disorders 0.3533283040805871 0.9521735541674122 0.3410089707066386 1.0 0.743310403468392 74 P53007,P28288,P35670,O15118,P56589,Q16134,P49711,P00374,P40855,O75381,O43772,Q6PGP7,Q9UJS0,P61916,P49748,P51812,O75844,Q14739,P02545,P98175 20 +Short femur 0.6299225123354304 0.9515451087293458 0.3413277311194864 1.0 0.7436580385426421 5 Q9UHX1 1 +Butterfly vertebrae 0.5737566732228064 0.9511421420197398 0.3415322244276519 1.0 0.7436712710884538 2 Q9Y2W2 1 +Hemivertebrae 0.4674019157915773 0.9505636967176552 0.3418259047978587 1.0 0.7436712710884538 14 P21281,Q9Y619,Q9UHX1,O60826,Q9UM00,P16435 6 +Abnormality of subcutaneous fat tissue 0.4550032507906565 0.949442482569016 0.342395612340167 1.0 0.7441680364765416 16 O00255,O75844,P36543,O75431,P02545,Q6NUK1 6 +Abnormal esophagus physiology 0.3182386176867087 0.9486869459319688 0.3427798552780896 1.0 0.7443902996713491 233 Q9UGP8,Q14108,Q9NZJ7,P55795,P53007,P01889,Q9UHX1,P51571,P35670,O15118,Q01105,O76024,Q6NUK1,Q9UBM7,P12235,Q99720,Q86TI2,Q96RL7,P21964,Q12959,P82663,O14678,P49711,Q8N183,P21912,O95202,Q96A33,Q92581,P20700,O00255,P04062,P82930,P03886,Q13510,Q8IZA0,O43819,P16435,P61916,Q9NR77,P49748,Q9Y619,P07602,Q6ZXV5,Q9Y4P3,P35637,Q14739,O60826,O60313,P05067,O15269,P14314,Q8WWI5 52 +Lower limb pain 0.6289334878119783 0.9474787619273292 0.3433948734288869 1.0 0.7450328364495694 5 O75477,O95140,Q8WVX9 3 +Extramedullary hematopoiesis 0.6502933646963798 0.9437911862103636 0.3452763654497468 1.0 0.7469584031977017 4 Q14739 1 +Biparietal narrowing 0.4854805294496546 0.9437548893731004 0.3452949175960058 1.0 0.7469584031977017 12 O43924,Q10713 2 +Aplasia hypoplasia of the sacrum 0.6479664256088145 0.9435455684236956 0.3454019187358401 1.0 0.7469584031977017 3 Q8TAA9 1 +Optic nerve hypoplasia 0.4293706554581511 0.943143909408832 0.3456072988556933 1.0 0.747055777017237 20 P37268,Q9UHX1 2 +Increased circulating lactate dehydrogenase concentration 0.4597316262366018 0.9400655120167666 0.3471839578084568 1.0 0.7494229768875103 15 Q9UJS0,P23786,P10253,Q96RL7 4 +Abnormal ilium morphology 0.4204328371063739 0.9379826630176836 0.3482533197722801 1.0 0.7513838955715231 22 Q7RTS9,P51812,Q8TAA9,P16278 4 +Abnormality of the ankles 0.3691832186256138 0.9360653027340666 0.3492395662721144 1.0 0.7521228661910548 44 Q9NZJ7,P07602,O75844,Q9Y4P3,Q7RTS9,P49589,P02545 7 +Focal onset seizure 0.3306841411088338 0.934646907185734 0.3499702967814999 1.0 0.7521228661910548 92 Q9NZJ7,P22466,P07602,O75503,Q01105,Q9UBX3,P03886,P21912,Q96N66,P00403 10 +Varicose veins 0.6257107933488156 0.9342410103643354 0.3501795855327236 1.0 0.7521228661910548 5 P04062 1 +Venous insufficiency 0.6257107933488156 0.9342410103643354 0.3501795855327236 1.0 0.7521228661910548 5 P04062 1 +Abnormal systemic blood pressure 0.324170551249959 0.9341623080945048 0.3502201752300444 1.0 0.7521228661910548 103 Q9NZJ7,Q10713,P01889,Q8TAA9,Q9BUB7,P21964,O43681,P21912,O43772,P04062,P03886,P16435,P00403,Q13423,P07602,P42892,O75844,Q9Y4P3,P02545 19 +Impaired proprioception 0.3686853713223603 0.9331256878583004 0.3507550774754895 1.0 0.7521228661910548 39 P41440,Q9NR77,P20700,Q9Y619,Q8WVX9,O95140,Q9Y6B6,Q8IV08,O14773,O43819,P54802,Q96RL7 12 +Female hypogonadism 0.6254146515876711 0.9330255271842088 0.3508067884090544 1.0 0.7521228661910548 5 O75844,P02545 2 +Congenital sensorineural hearing impairment 0.6249690907502498 0.9311970833536116 0.3517516263338709 1.0 0.7530162051136374 5 Q16740 1 +Transposition of the great arteries 0.5679634710929083 0.9284808300661592 0.3531582071775303 1.0 0.7539729306422756 7 O75844 1 +Increased circulating acth level 0.62429962943562 0.9284505375772792 0.3531739138272918 1.0 0.7539729306422756 5 O00170,P16435 2 +Abnormality of the pharynx 0.3660936138767238 0.928151613509016 0.3533289295877702 1.0 0.7539729306422756 55 Q03519,Q969G3,P21964,Q13432,P01889,P08236,Q9H0U3,Q7RTS9,Q03518,P16278,Q13510,P00813,P54802,Q86YV9 14 +Abnormality of the proximal phalanx of the thumb 0.6440251216554875 0.9277656787785292 0.3535291308727177 1.0 0.7540555102990951 3 O60828 1 +Insulin resistance 0.4300992972216709 0.9236596455897076 0.3556635488129114 1.0 0.757569849182246 19 Q03252,O75844,O75431,O76024,P02545 5 +Low set posteriorly rotated ears 0.3454836548518443 0.919538627363501 0.3578139110959468 1.0 0.7600696773917087 78 Q8NCH0,O43924,Q10713,Q15427,Q6NUK1,O75381,P04062,P49711,Q9UBM7,Q9Y4P3,O95202,Q15392,P56589,P37268,Q9UM00,Q5H8A4,P16435 17 +Pneumonia 0.3637620647161447 0.9177990878329648 0.358724059904735 1.0 0.7613102889523672 58 P49748,Q13432,P04062,P16278,Q6NUK1,Q13510,P00813 7 +Dysdiadochokinesis 0.4557633311535866 0.9162129960119864 0.3595551904572533 1.0 0.7621210162535181 15 O75503,Q6DKK2,P20700,P49589 4 +Hepatocellular adenoma 0.5658892947457117 0.9153781100620711 0.3599931659796094 1.0 0.7621210162535181 2 P10644 1 +Subependymal cysts 0.5658892947457056 0.9153781100620452 0.3599931659796231 1.0 0.7621210162535181 2 Q9BSJ2 1 +Maturity onset diabetes of the young 0.5658892947457056 0.9153781100620452 0.3599931659796231 1.0 0.7621210162535181 2 P61457 1 +Premature ventricular contraction 0.5648138803597971 0.9143117432538166 0.3605530617617285 1.0 0.7623166797077601 7 O43772 1 +Increased adipose tissue 0.6427634034170022 0.9138626035340108 0.3607890459927283 1.0 0.7623166797077601 4 P02545 1 +Limited wrist movement 0.6206315676601326 0.9134175800976964 0.3610229630236936 1.0 0.7623166797077601 5 O75844 1 +Metaphyseal striations 0.60239096910745 0.9103636518825012 0.3626307602109477 1.0 0.7642360241543718 6 Q13126,Q9UG56 2 +Joint contracture of the hand 0.3624797449207364 0.9098449109007803 0.3629043058369663 1.0 0.7642360241543718 59 Q9NR77,P42892,O75844,Q15392,Q8IZA0,P02545,P16435 7 +Abnormal epidermal morphology 0.4279537571836011 0.9092605235733826 0.3632126231738168 1.0 0.7642360241543718 19 P16615,P01889,O75844,Q14574,P02545,Q06136 6 +Lipoma 0.6194104493756031 0.9084191131040976 0.363656831363536 1.0 0.7642462434275736 5 Q8TAA9 1 +Pituitary growth hormone cell adenoma 0.6192350956130308 0.9077015854974804 0.3640359060575977 1.0 0.7642462434275736 5 Q14697,O00255,P10644,O00170 4 +Tetraplegia tetraparesis 0.365274118670036 0.9046550894451348 0.3656481405229039 1.0 0.7650566514072243 49 Q13423,Q9NZJ7,P20700,P07602,Q96T60,O43681,P51572,Q7RTS9,P35637,Q9UBX3,P21912,P17900,P51970 13 +Patchy hypopigmentation of hair 0.6182198800310846 0.9035487254005964 0.3662347403082746 1.0 0.7650566514072243 5 Q9UM00 1 +Stuttering 0.6401044628104722 0.9033236218897516 0.3663541631553455 1.0 0.7650566514072243 4 P03886 1 +Congestive heart failure 0.3552707299941348 0.9025993944389366 0.3667385480584253 1.0 0.7651037894927559 68 O75880,Q02978,P22626,P09493,P02545,Q9Y4P3,Q70HW3,Q9BUB7,Q9Y375,P21912,P03886,P16278,P10253,O43819,P40939,Q9BTV4,P00403 17 +Scleroderma 0.600433835774432 0.9021443353204344 0.36698020001519 1.0 0.7651851960962327 6 Q14739 1 +Involuntary movements 0.3066484507555106 0.9012919475349463 0.3674331140817635 1.0 0.7651851960962327 351 O43924,Q14108,Q9NZJ7,Q10713,Q8NI60,P55795,Q03252,Q86VD7,Q9UHX1,P35670,O76024,Q01105,Q9BUB7,P49589,P13073,O75477,P12235,Q99720,Q6P4A7,O14949,Q96RL7,Q969G3,Q96CU9,Q8WVX9,O75503,O43681,O95140,O96008,P50897,P21912,Q9NZ01,P00374,O95202,Q9NWS8,Q5XKP0,Q92581,Q8N2K0,P20700,P22626,Q9NQZ5,O00255,P04062,Q6DKK2,P82930,Q9BWD1,P03886,O43292,Q969X5,Q13510,Q02978,O43819,Q9UJS0,P00403,O60313,P61916,Q9NR77,P41440,Q2M389,P07602,Q96T60,Q9P0J0,Q9H078,Q9Y4P3,O14656,P35637,P27544,Q9UBX3,P17900,O14773,P05067,Q96N66,Q96IX5,Q9NPL8,Q9Y287 74 +Meningitis 0.5242052294588279 0.9003892672387562 0.3679131304411729 1.0 0.7658003757962922 8 P01889,Q8TAA9 2 +Chorioretinal atrophy 0.6392859323187442 0.9000825425511931 0.3680763256144257 1.0 0.7658003757962922 4 P40939 1 +Abnormality of the supraorbital ridges 0.4030398997253859 0.8998115053397799 0.3682205704996093 1.0 0.7658003757962922 25 Q6NUK1,O75381,P51812,Q6PGP7,P56589,P98175,P16435,P40855 8 +Abnormal form of the vertebral bodies 0.3278925889935056 0.8979144148575208 0.3692311790710814 1.0 0.7671885286003892 92 Q10713,Q9UHX1,Q8TAA9,P16278,Q6NUK1,Q9UBM7,Q5H8A4,Q15427,Q96HY6,O95202,P08236,P07237,Q7RTS9,Q9UM00,P54802,P16435,Q9Y619,P51812,Q9Y4P3,Q14739,O60826,P00813 22 +Abnormal size of the clitoris 0.4329642925763564 0.8949142909270844 0.3708329067173286 1.0 0.7691776283710383 18 Q9Y619,O75381,P53701,P56589,Q9UBM7,P16435,P40855 7 +Impairment of activities of daily living 0.3584102793025183 0.8929282961172642 0.3718955728046385 1.0 0.7703551150953225 63 Q9NZJ7,Q969G3,P21964,P20700,P07602,Q8WVX9,P51812,P07196,O00255,O43681,Q8TAA9,P35637,Q92796,O15269,Q99720,Q92581 16 +Abnormal liver morphology 0.3164497888092402 0.8919280580027978 0.3724314944564362 1.0 0.7711231253290912 260 Q9UGP8,Q14108,Q9NZJ7,Q03252,P10619,P53007,Q9HC21,Q10713,P28288,Q9NVI7,P35670,Q9H0U3,O15118,Q9BUB7,P16278,P56589,P22830,Q01844,P23786,Q96RL7,Q8N511,Q96CU9,Q07021,O43676,Q9Y6M9,Q8IY17,Q16134,O95140,P33991,P14927,P04066,O75431,Q9Y6B6,Q8N183,Q96HY6,Q96I36,P00374,Q9Y4L1,Q9NWS8,Q5XKP0,Q9Y285,Q96A33,P40855,P08236,O75880,P09601,O75381,P22626,O43772,O96000,P04062,Q86Y39,Q6PGP7,P03886,P10253,Q13510,O75380,Q9BT22,Q9UJS0,P54802,P61916,P49748,Q9Y619,P07602,Q9HC07,Q8TB37,Q9H078,P40939,Q9Y375,Q14739,Q9NX14,P02545,Q13724,P14314,P00813,Q9NPL8 76 +Vegetative state 0.615121793004102 0.8908895247827741 0.3729884405485657 1.0 0.7719339667204137 5 Q9NZJ7,P07602 2 +Delayed epiphyseal ossification 0.6368090799929703 0.8902847191634986 0.3733130241223263 1.0 0.7722634070124688 4 Q9UG56 1 +Choreoathetosis 0.3767340097616941 0.8891771535677665 0.3739078791922761 1.0 0.7724782097073166 32 Q86VD7,Q9P0J0,Q9H078,P82930,Q5XKP0,Q96RL7 6 +Deep palmar crease 0.4657476007274509 0.8854105372425373 0.3759352512662053 1.0 0.7724782097073166 13 P21281,O75431,Q9Y487,O00170,Q6NUK1,P98175 6 +Ovoid vertebral bodies 0.5001884885692758 0.8851717001977739 0.3760640331258793 1.0 0.7724782097073166 9 P54802 1 +Abnormality of the phalanges of the toes 0.4037094525066772 0.8837616695749977 0.3768248819412623 1.0 0.7729231933067744 24 Q96T60,Q7LGA3,O75844,O75431,P02545 5 +Cutis laxa 0.3878214599312006 0.8833108368832863 0.3770683502509353 1.0 0.7729231933067744 29 Q8NCH0,P51812,O96000,Q9Y4P3,P38435 5 +Metaphyseal dysplasia 0.4653638997138197 0.8832367273589385 0.3771083817418788 1.0 0.7729231933067744 13 Q7RTS9,Q9HC07 2 +Unilateral renal agenesis 0.4083110421169864 0.8829038723170461 0.3772882112373676 1.0 0.7729524608456646 23 Q86XL3,Q9UBM7,Q9UHX1,P16435 4 +Spastic paraparesis 0.4233133869323259 0.8781334244727854 0.3798713160144522 1.0 0.7765216380008866 19 Q8WVX9,P04062,Q6DKK2,P21912,Q5XKP0 5 +Abnormal atrioventricular valve physiology 0.3619956885364269 0.8770946285367686 0.3804352420018422 1.0 0.7765216380008866 52 Q8WVX9,P51812,P09493,P01889,O75844,P04062,P36543,O75431,P49711,Q9Y4P3,P53701,Q9NX14,P02545,Q6NUK1,O43819,P40939 16 +Abnormality of cardiovascular system electrophysiology 0.3181798029781943 0.8758542843622396 0.3811092547846233 1.0 0.7770301792966839 120 Q9NZJ7,P13473,P01889,Q9BUB7,P56589,Q9H490,P23786,P12235,P50402,P09493,Q8TB36,P21912,Q9BTV4,P40855,P51970,O75880,O75381,O00255,O43772,P04062,P03886,P10253,Q02978,P00403,P49748,P07602,P42892,Q9Y4P3,O14656,P53701,P02545,P40939 32 +Enlarged thorax 0.4187759243533332 0.8706392532844469 0.3839511565575029 1.0 0.7792996790277672 20 O75844,Q14739,P02545 3 +Hypoplasia of teeth 0.4066012417337548 0.8704429624025599 0.3840583768350594 1.0 0.7792996790277672 23 O75844,P51648,P02545 3 +Preaxial polydactyly 0.4356402490428736 0.8689040505634776 0.3848996138681855 1.0 0.7804816534843565 17 O43924,Q9UHX1,Q5H8A4 3 +Anteriorly placed anus 0.471796051934036 0.8684739024627367 0.3851349530843131 1.0 0.7804816534843565 12 Q6NUK1,P49748,P53701,P16435 4 +Atrophy degeneration affecting the central nervous system 0.3097139825343538 0.8665660492474561 0.3861798223724293 1.0 0.7812277255878997 328 O43924,Q9NZJ7,Q10713,Q9UHX1,O15118,Q01105,O76024,P49589,Q9BUB7,P13073,P16278,Q9H490,Q5H8A4,Q99720,Q96RL7,Q5BJH7,Q8N766,Q8WVX9,O14678,O75503,O96008,Q15165,P50897,Q9NZ01,Q9NWS8,P00374,O15121,Q96A33,P40855,P51970,Q92581,P08236,O75880,P20700,Q2TAA5,P22626,P04062,Q6DKK2,Q9UPT5,Q86Y39,P51572,P03886,Q13510,Q9BT22,Q9UM00,O75352,O43819,Q96TA2,P00403,O60313,Q6UX04,Q2M389,P07602,P51812,Q96T60,Q7LGA3,Q8NHS3,Q9H078,Q9Y320,Q9Y4P3,P35637,P17900,O14773,P05067,Q96N66 65 +Abnormal t cell morphology 0.4413652158098352 0.8653406393188758 0.3868518515355243 1.0 0.7815684365913642 16 Q13432 1 +Tibial torsion 0.5543692048328124 0.8634274093019345 0.3879025148157029 1.0 0.7822031212669855 2 Q9Y5S9 1 +Abnormal liver physiology 0.5910157096610545 0.8627031771208713 0.3883006851242416 1.0 0.7824547717848732 6 Q13510 1 +Abnormality of the shoulder girdle musculature 0.359718865054938 0.8618307519746343 0.3887806597974033 1.0 0.7827003011948351 35 P50402,Q9NZJ7,P07602,O60313,P02545,Q9BTV4 6 +Retrognathia 0.3304852852927568 0.8613242658102968 0.3890594745939633 1.0 0.7827003011948351 85 P53007,Q9UHX1,Q9BUB7,Q6NUK1,P37268,Q8N766,Q8NCH0,Q15427,Q15392,Q2TAA5,P04062,Q9UPT5,Q9Y619,Q7LGA3,O75844,Q9NX14,P53701,P02545,Q13724 19 +Severe muscular hypotonia 0.3596568996590695 0.8612650012584462 0.389092106997726 1.0 0.7827003011948351 35 O43505,P53007,O75381,Q9NWM8,Q01105,Q9NWS8,P02545,P56589,O75380,Q5H8A4 10 +Aplasia hypoplasia of the cerebral white matter 0.5159360740754224 0.8606398172921897 0.3894364489014872 1.0 0.7827003011948351 8 P03886,P00403 2 +Transient ischemic attack 0.5156138173197186 0.859093919338627 0.390288701811917 1.0 0.7827003011948351 8 O75844 1 +Hypomimic face 0.4786813498496853 0.8588124148760792 0.3904440170235037 1.0 0.7827003011948351 11 P04062 1 +Focal tonic seizure 0.5532452936217935 0.8583884598475914 0.3906779977331587 1.0 0.7827003011948351 2 Q9H936 1 +Skin plaque 0.5898085354723102 0.8576622210657432 0.3910790066888658 1.0 0.7827003011948351 6 Q06136 1 +Glycosuria 0.5149196003593901 0.8557645602895833 0.3921280217089293 1.0 0.7827003011948351 8 P02545,P35670 2 +Ulnar deviation of the wrist 0.6257613197151433 0.8551676352143446 0.3924583507079591 1.0 0.7827003011948351 3 P16435 1 +Abnormal ossification involving the femoral head and neck 0.6060821742343279 0.8540810099443631 0.3930601050892646 1.0 0.7827003011948351 5 Q14739 1 +Abnormality of renal excretion 0.5513552416676785 0.8539920285965379 0.3931094061813143 1.0 0.7827003011948351 7 O43772 1 +Bird like facies 0.5145222471762037 0.8538594548634583 0.3931828670619062 1.0 0.7827003011948351 8 O75844 1 +Posteriorly rotated ears 0.3165600953145827 0.8522872999990254 0.3940546530855626 1.0 0.7834235660111876 124 Q8NCH0,O43924,Q10713,O43505,P42892,Q9HC07,Q7LGA3,P04062,Q9UHX1,Q9UBM7,O95202,Q15392,Q9H490,P37268,Q9UM00,P23786,Q5H8A4,P16435 18 +Abnormality of the musculature of the lower limbs 0.3874377450639438 0.8519897021751038 0.394219807622763 1.0 0.7834235660111876 28 P50402,Q9NR77,P53007,O14979,P02545,Q9BTV4,Q96RL7 7 +Retinal vascular tortuosity 0.4598130052322772 0.8518225869940127 0.3943125680287622 1.0 0.7834235660111876 13 P21964,P03886 2 +Abnormality of the ribs 0.3445628007572682 0.8505556866586292 0.3950162142273032 1.0 0.7836933721171121 74 Q9UHX1,Q8TAA9,P16278,Q9UBM7,Q5H8A4,Q15427,O75431,Q96HY6,O95202,P07237,Q7RTS9,Q9UM00,P54802,P16435,Q9Y619,O75844,O14656,Q14739,O60826,P02545,P00813 21 +Aplasia hypoplasia of the femur 0.4440810038661928 0.8461334386683474 0.3974783085349544 1.0 0.7847278877869995 15 Q9UHX1,O75431,O00116 3 +Polydactyly 0.3592506409646169 0.8458719959504402 0.3976241563266438 1.0 0.7847278877869995 50 O43924,Q10713,P21964,Q9UHX1,Q9UM00,Q14739,Q9UBM7,Q5H8A4 8 +Low alkaline phosphatase 0.6254816016323386 0.8456735614119733 0.3977348760634798 1.0 0.7847278877869995 4 Q92643 1 +Abnormality of the wrist 0.3716172024231849 0.845208649518344 0.397994353882976 1.0 0.7847278877869995 32 O75844,P02545,Q13510,P16278,P16435 5 +Lipodystrophy 0.3585291467530221 0.8436478196018556 0.3988662341038571 1.0 0.7861150050784756 37 P42167,P50402,P09493,O75844,O75431,P02545,Q6NUK1,Q9BTV4 8 +Telangiectasia 0.359198975070073 0.8425207528106622 0.3994965284031844 1.0 0.7863239516834857 40 Q14739,P03886,P21912,Q8IZA0,P02545 5 +Abnormal involuntary eye movements 0.3103593871895302 0.8389172676987635 0.4015157371505098 1.0 0.7887274951393095 315 O43924,Q9NZJ7,Q10713,Q9NPL8,P53007,P01889,Q9NVI7,Q9H061,O76024,Q8TAD8,P49589,Q53H12,Q6NUK1,Q9H490,P56589,Q9UBM7,P12235,Q5H8A4,Q99720,Q86YV9,Q96CU9,O43676,Q9Y6M9,O75503,Q8N183,P21912,O95202,Q15392,Q6P4Q7,Q5XKP0,O15121,Q92581,P20700,O75381,O43772,O96000,P04062,Q6DKK2,P82930,Q86Y39,P03886,O43292,Q13510,O75380,Q9BT22,O60313,P41440,Q9NR77,P07602,Q7LGA3,Q9P0J0,Q8TB37,Q9H078,Q9Y4P3,P35637,Q8WWV3,P17900,O14773,Q9Y375,Q8IV08 60 +Increased connective tissue 0.5113925436101633 0.8388683114970125 0.4015432118111242 1.0 0.7887274951393095 8 O75431,P02545 2 +Lacticaciduria 0.6227940922781617 0.8351407328234155 0.4036384747695432 1.0 0.791178857556254 4 P03886 1 +Fractures of the long bones 0.6202177019923734 0.8333260679657108 0.4046608583265108 1.0 0.7915667008794012 3 Q13126 1 +Non motor seizure 0.3578188678997345 0.8330102104798726 0.4048389707938324 1.0 0.7915667008794012 51 P22466,P51812,Q01105,O43292,P00374,Q13510 6 +Sepsis 0.4013731711830506 0.8323648520145323 0.4052030350217239 1.0 0.7915667008794012 23 P42892,P01889,P49711,Q9BT22,P00813 5 +Plantar hyperkeratosis 0.3699743024683724 0.8310937670942822 0.4059206605517755 1.0 0.7919961662557158 32 P42167,P16615,P09493,P21912,P02545,Q06136 6 +Abnormal periventricular white matter morphology 0.3581673563628149 0.8298165802168349 0.4066424950709868 1.0 0.7923998541596036 44 Q9NZJ7,P07602,O75503,Q9UHX1,P51571,O95202,P17900,O60313,O15121 9 +Agammaglobulinemia 0.5467828041584704 0.8295254858835356 0.4068071215293574 1.0 0.7923998541596036 2 Q8IWT6 1 +Chronic diarrhea 0.4090226029257942 0.8286570220888737 0.4072985116627992 1.0 0.7925671458288174 21 Q13510,Q9BT22,Q96A33 3 +Abnormal sternum morphology 0.3149189055686829 0.8278981472077606 0.4077281843292544 1.0 0.7925671458288174 121 P55795,Q9UHX1,Q9NVI7,P16278,Q9H490,Q8NCH0,P50402,O75431,P21912,O95202,Q96A33,Q9BTV4,P04062,Q7RTS9,Q13510,P51812,Q7LGA3,Q9Y4P3,Q14739,P02545 20 +Polyhydramnios 0.3565795384710797 0.827345811414368 0.4080410849879234 1.0 0.792818903790518 54 P21964,O75844,Q9NVI7,P04062,Q9UM00,Q70HW3,Q14739,P02545,Q9UBM7 9 +Abnormality of the upper arm 0.4047982295709986 0.8265092366349986 0.4085152806307475 1.0 0.7934100853847588 22 P50402,O00116,P02545,Q9BTV4,P16435 5 +Death in infancy 0.3491091922803758 0.8246701704605481 0.4095588713195905 1.0 0.7950063252263224 67 Q9NZJ7,P49748,Q6NUK1,P07602,O75381,Q9HC21,P04062,O14656,Q9BUB7,Q9Y3C6,Q9NWS8,O60826,P16278,P56589,Q9BT22,P02545,P40855,O60508 18 +Thin ribs 0.4403341906174912 0.8237168753615606 0.4101004485405868 1.0 0.7954960507835479 15 O75844,Q9Y619,O75431,P02545 4 +Scrotal hypoplasia 0.407965107378721 0.8212877161540294 0.411482402965132 1.0 0.7961865316483429 21 P46977,Q8IWS0,Q8TCJ2,Q6NUK1,Q9UBM7,P16435 6 +Lack of peer relationships 0.5448159595391855 0.8207803070532718 0.4117714177376601 1.0 0.7961865316483429 2 Q96CW1 1 +Corneal ulceration 0.5978299813704688 0.8206648900734552 0.4118371748170979 1.0 0.7961865316483429 5 O75844 1 +Tics 0.5435898179462751 0.8193863283795408 0.4125660326334124 1.0 0.7969676484755492 7 Q9UHX1 1 +Urinary retention 0.5974080728697106 0.8189616382082339 0.4128083008709304 1.0 0.7971058547420902 5 Q8TAA9 1 +Limitation of joint mobility 0.3133660995099686 0.8162945183318776 0.4143317088309672 1.0 0.7973446817782938 110 Q9HC21,P01889,Q8TAA9,O76024,P16278,P37268,P23786,P50402,Q15427,O75431,O95140,Q9BTV4,Q7RTS9,Q969X5,P51648,Q9BT22,P54802,P16435,Q7LGA3,O75844,Q9Y4P3,O14656,P02545 23 +Turricephaly 0.4782380866295358 0.8136713493478072 0.4158332515855718 1.0 0.798981667346928 10 Q6NUK1,P21964,P16435 3 +Infectious encephalitis 0.4699507568205729 0.8124339355607096 0.4165426803939787 1.0 0.7991964858629111 11 Q9Y4L1,P01889,Q9BUB7,Q14739 4 +Abnormal systemic arterial morphology 0.3079434628107078 0.8123166116219864 0.4166099810961881 1.0 0.7991964858629111 157 Q9NZJ7,P10619,P01889,Q9UHX1,O15118,P49589,P16278,Q6NUK1,Q9UBM7,P21964,Q9NWM8,P21912,P04062,P03886,P61313,Q13510,P07602,Q7LGA3,O75844,Q6ZXV5,Q9Y4P3,P53701,P17900,P02545,P38435 25 +Cerebral visual impairment 0.3433951634765059 0.8122821719874965 0.4166297379717982 1.0 0.7991964858629111 72 Q5BJH7,Q8N766,P20700,P53007,Q96N66,Q01105,Q9NZ01,P03886,Q9H490,P37268,Q96A33,P12235,P00403 13 +Abnormal intraocular pressure 0.5788281420308085 0.8119802261507091 0.4168029779441438 1.0 0.7992004533967997 6 Q8NCH0,P29992,P04439 3 +Abnormality of somatosensory evoked potentials 0.6165366395854026 0.8107003669008979 0.4175377626032157 1.0 0.8002130714229327 4 Q9NQZ5 1 +Abnormal peripheral nervous system morphology 0.3017811435838406 0.8104634550985761 0.4176738605820704 1.0 0.8002130714229327 179 Q9NZJ7,P53007,Q9HC21,Q9UHX1,Q9NVI7,O76024,P56589,P12235,Q99720,Q96RL7,Q969G3,O43681,O95140,Q8TB36,P21912,O15121,P40855,Q8N2K0,P20700,O75381,P22626,O00255,Q6DKK2,Q92796,P03886,Q02978,Q13510,O43819,Q96TA2,P00403,O60313,P41440,Q9NR77,P07602,P51812,Q96T60,P35637,P02545,O15269,Q8IV08 40 +Abnormality of the pubic bone 0.4694995424567831 0.8100426943907477 0.4179156380875453 1.0 0.8003478729412423 11 Q8IZA0,O95202,Q5H8A4 3 +Ophthalmoparesis 0.334826807177239 0.8074139157639223 0.4194280522389351 1.0 0.8005191628181435 79 P11047,Q10713,P53007,P01889,Q9BQP7,O76024,Q9Y4W6,O00483,P12235,Q969G3,Q96CU9,Q07021,Q8N183,O00170,P21912,Q92581,O43837,O00255,P04062,P03886,Q16795,O43819,O60313,P00403,O14908,Q9P0J0,O75251,Q96IX5,O75306 29 +Upper limb muscle weakness 0.3813574474560376 0.8035425621348045 0.4216612064983822 1.0 0.8018723022612098 28 P50402,Q969G3,O14908,P07196,P36551,O95140,P50336,Q969X5,P02545,Q9BTV4 10 +Short nose 0.315883257467859 0.8018436348895234 0.4226434142032278 1.0 0.8028161517147562 101 Q8NCH0,Q969G3,P20700,Q8WVX9,P42892,O75844,P04062,Q9UHX1,Q9NVI7,Q9Y4P3,O60826,Q15392,Q6NUK1,Q9H490,Q9UM00,P16435,P38435 17 +Muscle spasm 0.3525690847638077 0.8008907868822785 0.4231948742176148 1.0 0.8029605953478642 58 P05023,P49748,Q9NR77,Q8WVX9,P13473,P04062,P35637,P40939,Q15165,P23786,P12235,Q5H8A4 12 +Tonic seizure 0.3871727839279414 0.8008375892900699 0.4232256746910003 1.0 0.8029605953478642 26 Q9NZJ7,P07602 2 +Ureteral duplication 0.4829420653053698 0.798637432735419 0.42450067580258 1.0 0.8029605953478642 9 O75844,Q8TAA9,P02545 3 +Proximal amyotrophy 0.4303990681986045 0.7979640204300841 0.4248913697051328 1.0 0.8031439449986646 16 P50402,O14979,P35637,P02545,Q9BTV4 5 +Pulmonary infiltrates 0.4827517042390729 0.7976869258351164 0.4250521927804027 1.0 0.8031439449986646 9 P04062 1 +Abnormal bleeding 0.3125120794686453 0.7956972058681785 0.4262080512965762 1.0 0.8038729887143133 116 Q14108,P01889,Q9UHX1,P35670,O76024,P23786,Q86YV9,Q8NCH0,Q969G3,P21964,P49257,Q9NWM8,P49711,P21912,Q4KMQ2,P11117,O00255,P04062,Q02978,Q9UJS0,Q13126,O75844,P12814,Q6ZXV5,Q14739,P02545,P05067,P14314,P38435 29 +Aplasia hypoplasia involving bones of the thorax 0.3542441352444219 0.7941586499233833 0.4271030774710636 1.0 0.8044532131993409 41 Q9Y619,Q15427,O75844,Q9UHX1,Q8TAA9,O75431,O14656,Q7RTS9,Q96HY6,Q14739,O60826,P02545,P16435 13 +Aplasia hypoplasia of the nipples 0.4104829068503235 0.7922507128176204 0.4282145040171898 1.0 0.8048784597186013 19 P10586,O95202,Q6NUK1,Q96A33,Q5H8A4 5 +Nephrogenic diabetes insipidus 0.5383534700758535 0.7921837868044465 0.4282535208159206 1.0 0.8048784597186013 2 Q9H9C1 1 +Follicular hyperkeratosis 0.5373795007908806 0.7918343786862968 0.428457253769225 1.0 0.8048784597186013 7 Q9NWM8,Q9H488 2 +Bladder diverticulum 0.5364475706786617 0.7877102276904026 0.4308662217081878 1.0 0.8059753161680804 7 Q9NWM8 1 +Vaginal atresia 0.6083386483454275 0.7868778506622329 0.4313533746785847 1.0 0.8062782351279404 3 P16435 1 +Osteolysis 0.364821477327066 0.7868434166539604 0.4313735342363665 1.0 0.8062782351279404 32 O75844,Q14108,P04062 3 +Abnormality of skin physiology 0.3125989309857573 0.7824256750742814 0.4339644496639594 1.0 0.8076417072254949 104 Q92542,Q8NCH0,P49748,P21964,P16615,P35670,Q9UBM7,Q15800,P10321,Q14739,P21912,Q06136,P22830,Q96A33,P00813,P48449 16 +Abnormal adipose tissue morphology 0.3487580893038618 0.7823553063531669 0.4340057921243878 1.0 0.8076417072254949 62 P42167,P50402,Q03252,Q2TAA5,P27635,P09493,O00255,O75844,Q8TAA9,P36543,O75431,O95140,P21912,P02545,Q6NUK1,Q9BTV4 16 +Hypercholesterolemia 0.4555268361776523 0.7795186121810607 0.4356742780763927 1.0 0.8081572131371161 12 Q8N511,O75431,P02545 3 +Supernumerary bones of the axial skeleton 0.5709481563162503 0.779407502650608 0.4357397056506173 1.0 0.8081572131371161 6 Q9UHX1 1 +Focal myoclonic seizure 0.5343978423917279 0.7786493850235106 0.4361862793890103 1.0 0.8081572131371161 7 O75503 1 +Abnormality of upper limb joint 0.3114532146139578 0.777709594038356 0.436740234949716 1.0 0.8081572131371161 127 P50402,Q9NR77,P42892,Q7LGA3,O75844,Q7RTS9,Q9BUB7,P23786,O95202,Q15392,Q13510,Q8IZA0,P37268,P02545,P16278,Q9BTV4,P16435 17 +Abnormal aortic valve cusp morphology 0.3812091814449673 0.7775350249834392 0.4368431785030653 1.0 0.8081572131371161 27 Q9UHX1,Q9Y4P3,Q6PGP7,Q6NUK1,P37268 5 +Decreased circulating cortisol level 0.4783996216070403 0.77598863170212 0.4377556982466339 1.0 0.8081572131371161 9 Q13423,P16435 2 +Abnormality of primary teeth 0.4208474912240754 0.775525946687398 0.4380289395955856 1.0 0.8081572131371161 17 O75844,Q9UM00 2 +Increased serum iron 0.6053670936363261 0.7753409320130985 0.4381382285442359 1.0 0.8081572131371161 3 Q6PGP7 1 +Infantile spasms 0.3592991904513267 0.7742049773145253 0.4388095853720175 1.0 0.8081572131371161 33 Q13510,P03886 2 +Mesomelia 0.5332917215205925 0.773765608676223 0.4390694136155004 1.0 0.8081572131371161 7 Q14739 1 +Lower limb spasticity 0.3231701535445915 0.7684298585877807 0.4422318469743984 1.0 0.812162939188655 85 Q9NZJ7,Q96CU9,P07602,Q15041,Q9P0J0,P04062,Q6DKK2,Q8N183,P35637,P21912,O60313,P56589,Q5XKP0,O75477,Q99720 15 +Impaired temperature sensation 0.5680019077721041 0.7672793115146388 0.4429154662286747 1.0 0.812162939188655 6 Q9NR77,O15269 2 +Intestinal pseudo obstruction 0.4613474421385267 0.766951742715598 0.4431102078451041 1.0 0.812162939188655 11 P03886 1 +Abnormal posterior segment imaging 0.5844149209860418 0.7667830521944561 0.4432105144600644 1.0 0.812162939188655 5 Q6UX04,Q96S66 2 +Dermal translucency 0.4765462928803944 0.7667681854732044 0.4432193551194459 1.0 0.812162939188655 9 O75844,P02545 2 +Fibrous tissue neoplasm 0.4034642100521457 0.7661672234466513 0.4435768081673319 1.0 0.8121804381699109 20 P21912,Q15392 2 +Waddling gait 0.3732328734656162 0.7649777742142473 0.4442847795313174 1.0 0.8131453124088517 29 P50402,P07196,P53007,P22626,Q7RTS9,Q5T8D3,P02545,Q13510,Q9BTV4 9 +Ectopic kidney 0.4127168673800003 0.7633699158410364 0.4452428162822017 1.0 0.8131453124088517 18 Q9UHX1,Q8TAA9 2 +Moderate global developmental delay 0.4681793522148196 0.7620539664482564 0.4460277957175291 1.0 0.8131453124088517 10 P21912 1 +Abnormal circulating proteinogenic amino acid derivative concentration 0.3956094264358387 0.7611926689650347 0.4465419963624535 1.0 0.8131453124088517 22 O75880,O96000,P12694,P22695,Q9P0J0,Q9BUB7,P03886,Q5XKP0,Q9UJS0 9 +Anarthria 0.5660318436728218 0.7591858578589658 0.447741384649768 1.0 0.8131840827071019 6 P35637,Q99720 2 +Acanthocytosis 0.5660154642900568 0.7591186237866636 0.4477815993550689 1.0 0.8131840827071019 6 Q9Y6B6,Q96RL7,O14656 3 +Abnormality of the lower urinary tract 0.3088537541015455 0.7589502853533048 0.4478822965992344 1.0 0.8131840827071019 246 Q86XL3,Q9NZJ7,P27635,P01889,Q9UHX1,Q8TAA9,P51571,O76024,Q9BUB7,P49589,P56589,P37268,Q9UBM7,P12235,Q99720,Q5H8A4,P48449,Q8NCH0,Q969G3,P21964,Q8WVX9,Q9NWM8,O43681,P21912,O95202,P40855,P51970,Q92581,P20700,O75381,P22626,P04062,Q6PGP7,Q92796,P61313,Q9UJS0,P16435,Q9NR77,Q9Y619,P07602,P51812,P18077,O75844,Q9Y4P3,P35637,Q9UBX3,Q9NX14,P53701,P02545,O60826,P07196,Q8WWI5 52 +Aplasia hypoplasia of the bladder 0.5304860915987619 0.757676290201671 0.4486447963090456 1.0 0.8131840827071019 2 P23229 1 +Oral mucosal blisters 0.5304860915987619 0.757676290201671 0.4486447963090456 1.0 0.8131840827071019 2 P23229 1 +Blistering by histological location 0.5304860915987619 0.757676290201671 0.4486447963090456 1.0 0.8131840827071019 2 P23229 1 +Hypoplastic dermoepidermal hemidesmosomes 0.5304860915987619 0.757676290201671 0.4486447963090456 1.0 0.8131840827071019 2 P23229 1 +Falls 0.4942164143029683 0.7571155796982987 0.4489806209346823 1.0 0.8131840827071019 8 P21912,Q96RL7,Q8WVX9 3 +Hypoplasia of the uterus 0.4745353373646561 0.7567776512123908 0.4491830842778854 1.0 0.8131972937159547 9 P53701,Q16740 2 +Abnormal platelet volume 0.4940459669398629 0.7563093496623368 0.4494637437343152 1.0 0.8133607159295307 8 Q14739,Q6PGP7 2 +Short nail 0.564813947428603 0.7541891957519725 0.4507356242422582 1.0 0.8137495774520511 6 O75844 1 +Skin dimple 0.3684498544665841 0.7541113529095789 0.4507823609216421 1.0 0.8137495774520511 30 Q8TAA9,P49711,Q9Y4P3,Q969X5,O95202,P53701,Q9NX14,Q9UM00,Q5H8A4 9 +Abnormal morphology of the musculature of the neck 0.4231703480880412 0.7537368169612081 0.4510072698754501 1.0 0.8137495774520511 16 Q99720,O14656 2 +Agenesis of cerebellar vermis 0.6012913873414262 0.7516998298954342 0.4522315927341926 1.0 0.815239114469477 4 O43924 1 +Abnormality of epiphysis morphology 0.3430039061521413 0.7487311316585027 0.4540192758016208 1.0 0.8171996911016837 66 Q9UG56,O75381,P51812,Q7LGA3,Q9HC07,Q7RTS9,Q96HY6,O95202,O00116,P16278,P56589,Q14739,P38435,Q9UBM7,P16435,P40855,P08236 17 +Otitis media 0.3429213999800935 0.7478237657748902 0.454566465111837 1.0 0.8178053609977042 66 P21964,Q12959,Q13432,Q96A33,Q8N5M9,O95202,Q14739,P00813,Q9UBM7,Q5H8A4 10 +Abnormality of the ureter 0.3298783512600934 0.7475923402056437 0.4547060863461212 1.0 0.8178053609977042 79 Q86XL3,P21964,Q7LGA3,O75844,Q9UHX1,Q8TAA9,O76024,P21912,P02545,Q9UBM7,P23786,P16435 12 +Abnormal renal physiology 0.2977490527836696 0.7439790831514386 0.4568891294851465 1.0 0.8214152274032147 178 Q14108,Q10713,Q03252,P01889,Q8TAA9,P35670,O76024,P23786,Q8NCH0,Q96CU9,O43676,P49257,Q9Y6M9,Q16134,Q8N183,P21912,Q9NWS8,P40855,P09601,O00255,O43772,P04062,O96000,Q86Y39,P03886,Q02978,O75380,Q9BT22,P00403,P05023,Q8TB37,Q9H078,Q9Y4P3,Q9Y375,P00813,O95470,Q9NPL8 37 +Limb girdle muscle atrophy 0.4318066360671432 0.7430803493296323 0.4574330359654881 1.0 0.8217602327521601 14 P50402,P02545 2 +Abnormal number of granulocyte precursors 0.596523776577154 0.741220460103528 0.4585597797892289 1.0 0.8229256363355381 3 Q07020 1 +Spastic tetraparesis 0.3820003867446075 0.740676281205777 0.4588897440826187 1.0 0.8229580568835432 25 Q9NZJ7,P20700,P07602,Q7RTS9,P21912,P17900 6 +Abnormal tricuspid valve morphology 0.4477081793566474 0.737070530897356 0.4610794589226257 1.0 0.8245325987186363 12 P21964,P53701,O60826,P51812 4 +Abnormal brainstem morphology 0.3097839675884137 0.7342469410932595 0.4627982491077462 1.0 0.8245325987186363 103 Q10713,O60508,Q969G3,Q96CU9,O43676,Q9Y6M9,Q8N183,Q9Y3C6,O15121,P20700,O96000,Q9UPT5,Q86Y39,P03886,O75380,O43819,O43505,Q8TB37,Q9Y320,Q6ZXV5,O60313,Q9Y375,Q9NPL8 23 +Aplasia hypoplasia of toe 0.3472763995205585 0.7330453037870821 0.4635307983991903 1.0 0.8245325987186363 39 Q9UHX1,O95202,P13073,P02545,Q13510,P00813,Q9UBM7,Q5H8A4 8 +Vitritis 0.5964235888833386 0.7330420884014585 0.4635327594479523 1.0 0.8245325987186363 4 P53701,Q9NX14 2 +Senile plaques 0.5240236021354298 0.729604592960844 0.4656319139396287 1.0 0.8245325987186363 2 Q9UQN3 1 +Alexia 0.5240236021354298 0.729604592960844 0.4656319139396287 1.0 0.8245325987186363 2 Q9UQN3 1 +Grammar specific speech disorder 0.5240236021354298 0.729604592960844 0.4656319139396287 1.0 0.8245325987186363 2 Q9UQN3 1 +Expressive aphasia 0.5240236021354298 0.729604592960844 0.4656319139396287 1.0 0.8245325987186363 2 Q9UQN3 1 +Eeg with continuous slow activity 0.5240236021354298 0.729604592960844 0.4656319139396287 1.0 0.8245325987186363 2 Q9UQN3 1 +Lack of insight 0.5240236021354298 0.729604592960844 0.4656319139396287 1.0 0.8245325987186363 2 Q9UQN3 1 +Collectionism 0.5240236021354298 0.729604592960844 0.4656319139396287 1.0 0.8245325987186363 2 Q9UQN3 1 +Reduced vital capacity 0.5240236021354254 0.729604592960824 0.465631913939641 1.0 0.8245325987186363 2 P06753 1 +Reduced visual acuity 0.3078758093846965 0.7294746251927055 0.4657113840601679 1.0 0.8245325987186363 133 Q9NZJ7,Q10713,P30533,P01889,Q9UHX1,Q9H061,Q96S66,P16278,Q86YV9,Q969G3,O43676,Q9Y6M9,O43681,Q8N183,P50897,P21912,O96000,Q86Y39,P03886,O75380,P07602,O43505,Q8NHS3,Q8TB37,Q8WWV3,P53701,P17900,O60313,Q9Y375,Q9NPL8 30 +Soft skin 0.468961838914201 0.7291700183249732 0.4658976685663085 1.0 0.8245325987186363 9 Q9NWM8 1 +Decreased muscle mass 0.4070474749134351 0.726745225857384 0.4673820428456805 1.0 0.8247191073493886 18 Q8NCH0,P51659,P36543,Q8TAA9,P04066,O95202,Q9Y285,Q92581 8 +Malnutrition 0.5220663429007182 0.7244534770351057 0.4687873790117711 1.0 0.8265741210747581 7 P20700,Q12959 2 +Cerebral cortical atrophy 0.3072794816571942 0.72380833340237 0.4691834125236287 1.0 0.8268642838839657 113 O43924,P51970,P51812,Q7LGA3,Q92581,O75503,P04062,O96008,Q9Y4P3,O76024,Q9BUB7,P03886,Q9NWS8,Q9UM00,Q96RL7,P00403 16 +Neurogenic bladder 0.4525413167276078 0.7206765734060361 0.4711085290840684 1.0 0.8291900873133617 11 P56589,O76024,Q9H270,Q8TAA9 4 +Anterior uveitis 0.5907522936252494 0.7191361264814897 0.4720570500443037 1.0 0.8291900873133617 3 P01889 1 +Abnormal urine cytology 0.3467093721520011 0.7190355370621384 0.4721190239553632 1.0 0.8291900873133617 45 P09601,Q14108,P04062 3 +Knee flexion contracture 0.3706705526761888 0.7185880960819072 0.4723947500799306 1.0 0.8291900873133617 28 Q86XL3,P27635,Q7LGA3,P21912,Q969X5,P37268,O75477,P23786 8 +Distal amyotrophy 0.3415602032154923 0.7179706745078881 0.4727753687685854 1.0 0.8291900873133617 64 P53007,Q9NVI7,Q99720,Q96RL7,Q8IY17,O95140,Q9H0B6,Q8TB36,P21912,P43243,Q8N2K0,Q13510,Q16795,O14908,Q9NR77,Q96T60,P35637,P02545,O15269,P07196 20 +Absent thumbnail 0.5721177867984583 0.717950787902629 0.4727876309671672 1.0 0.8291900873133617 5 Q96T60,P21281,P09471 3 +Abnormal epiglottis morphology 0.5924220419246664 0.7177766787287072 0.4728949951910617 1.0 0.8291900873133617 4 Q13510 1 +Tetraparesis 0.3442698403434503 0.7162403787953198 0.4738429341853707 1.0 0.8295360553848878 36 Q9NZJ7,P20700,P07602,Q7RTS9,P35637,Q9UBX3,P21912,P17900 8 +Limb pain 0.4654781866476231 0.7119797638075693 0.4764773071587673 1.0 0.8325870311093879 9 Q8WVX9,O95140,O15269,O75477,P36551 5 +Megaloblastic anemia 0.4840645716860994 0.7093004515575091 0.4781380482719317 1.0 0.834400866326572 8 O76024,P00374 2 +Nonketotic hypoglycemia 0.5537660901606521 0.7091138428227602 0.478253833310382 1.0 0.834400866326572 6 P49748,P23786 2 +Sudden death 0.3693817576354937 0.7083680414059909 0.4787167333537447 1.0 0.834400866326572 28 P50402,P49748,Q9Y4P3,P02545,P40939,Q9BTV4 6 +Nausea and vomiting 0.3045265181138072 0.7046044520006123 0.4810564271733231 1.0 0.8355849919911629 145 Q9NZJ7,P01889,P51571,Q9UBM7,Q01844,P23786,Q969G3,Q96CU9,O43676,Q9Y6M9,P12694,Q16134,Q8N183,Q9Y6B6,Q15165,P21912,Q2TAA5,P11117,O00255,O96000,Q86Y39,P03886,Q02978,Q8IZA0,O75380,Q9UJS0,P00403,Q13423,P49748,Q9Y619,P07602,P42892,P22695,Q8TB37,Q9Y4P3,P35637,P40939,Q9Y375,Q9NPL8 39 +Hyperacusis 0.5168936854923245 0.7018985438766617 0.4827424370792026 1.0 0.8375787583510952 7 P17900 1 +Intracranial hemorrhage 0.3740296143140235 0.7000265462778771 0.4839107262408131 1.0 0.8383918525339441 26 Q969G3,P49257,O75844,P04062,P21912,P02545,P05067,P23786 8 +Erythroderma 0.4627730180669832 0.6986684112887134 0.4847592795125639 1.0 0.8383918525339441 9 P00813,P48449 2 +Supernumerary tooth 0.4817861537651677 0.6986302702556526 0.4847831213969584 1.0 0.8383918525339441 8 P62266,Q9UBM7,Q9UHX1 3 +Dysarthria 0.2982744394069492 0.6940379777414627 0.4876583924421795 1.0 0.8417290330175735 164 Q9NZJ7,Q14108,Q10713,P35670,O15118,O76024,P49589,O75477,P12235,Q96RL7,Q96CU9,O75503,O43681,Q8N183,Q5XKP0,O15121,P20700,P04062,Q6DKK2,O43292,P51648,P61916,P41440,P07602,Q96T60,Q9P0J0,Q8TB37,Q9Y4P3,O14656,P35637,O14773,Q8IV08 32 +Abnormal joint morphology 0.3050067095058954 0.6930678602586081 0.4882669661173437 1.0 0.8422374957819474 297 Q86XL3,Q9NZJ7,Q14108,Q5JTV8,Q15041,P01889,Q9UHX1,Q8TAA9,P35670,Q9BUB7,P49589,P10321,P16278,P37268,Q9UBM7,P23786,Q96RL7,Q8NCH0,P50402,P21964,P21912,O95202,Q15392,Q96A33,Q9BTV4,P04062,Q7RTS9,Q13510,Q8IZA0,P16435,Q9NR77,P07602,P42892,Q7LGA3,O75844,Q6ZXV5,Q9Y4P3,Q14739,P02545,P38435 40 +Decreased pulmonary function 0.5856162532712144 0.6919719189610923 0.4889549639088932 1.0 0.8422374957819474 4 Q969G3 1 +Aplasia hypoplasia of the optic nerve 0.3778568238549823 0.6916897375775591 0.4891321931011296 1.0 0.8422374957819474 24 P37268,Q9UHX1 2 +Intrauterine growth retardation 0.3022688574446662 0.6909168960537286 0.4896177674960273 1.0 0.8424351440371263 217 O43924,P27635,Q9UHX1,Q9BUB7,P49589,P16278,Q6NUK1,P37268,Q9UBM7,Q5H8A4,Q6P4A7,Q5BJH7,Q969G3,Q96CU9,P21964,Q15427,O43676,P82663,Q9Y6M9,Q8N183,P21912,O95202,Q15392,P07237,O75880,O96000,P04062,Q86Y39,Q6PGP7,P51572,P03886,O75380,Q9BT22,Q9UJS0,Q6UX04,Q9Y619,O75844,Q8TB37,O14656,Q8TCJ2,Q9NX14,P02545,P98175,P40939,Q9Y375,Q9NPL8 46 +Mandibular aplasia 0.565042413662703 0.6901327859069679 0.4901106869886535 1.0 0.8425356397459586 5 Q9Y619,P53701 2 +Sparse body hair 0.4538525229813803 0.6892029249046296 0.4906955764463654 1.0 0.8429203997159971 10 P48449,Q14574,P02545 3 +Azoospermia 0.4171421350739678 0.6859862826424609 0.4927217585604104 1.0 0.8451571971780149 15 P04062 1 +Corticospinal tract hypoplasia 0.5136274234335362 0.685017540777439 0.4933328523042959 1.0 0.8458946336425845 2 Q13045 1 +Neonatal onset 0.3845805430820772 0.6831675273886941 0.4945009892786758 1.0 0.8461601326154028 22 Q9H490,Q8TB36,P40939 3 +Abnormal rib cage morphology 0.3131210639083139 0.6831633129026676 0.4945036520802623 1.0 0.8461601326154028 88 Q9UHX1,Q8TAA9,P16278,Q9UBM7,Q5H8A4,Q15427,O75431,P04066,Q96HY6,O95202,Q14696,P08236,P07237,Q7RTS9,Q9UM00,P54802,P16435,Q9Y619,O75844,P50454,O14656,Q14739,O60826,P02545,P00813 25 +Skeletal muscle atrophy 0.2939806954742914 0.6820388475080388 0.495214386975747 1.0 0.8463725456270004 177 Q03252,P53007,Q9HC21,P13473,Q9NVI7,P49589,P16278,O75477,P12235,Q99720,Q6P4A7,Q96RL7,P50402,Q9NWM8,O95140,Q8TB36,Q15165,P21912,Q9BTV4,P51970,Q92581,Q8N2K0,P22626,Q6DKK2,Q969X5,Q13510,O43819,O60313,Q9NR77,O43505,P51812,Q96T60,Q13126,P35637,P02545,O15269,Q9NPL8 37 +Metatarsus adductus 0.4112890306317058 0.6814881641367823 0.4955626534445869 1.0 0.8463725456270004 16 Q9UBM7,O95202,Q03252,Q15392 4 +Abnormal circulating copper concentration 0.5120866991031907 0.681043637923714 0.4958438787240005 1.0 0.8463725456270004 7 O43819,P61966,P35670 3 +Renal hypoplasia aplasia 0.3086255617282872 0.6795007061581957 0.4968206603473122 1.0 0.8463725456270004 98 Q86XL3,O43924,P21964,Q7LGA3,Q9UHX1,Q8TAA9,Q6PGP7,Q9Y4P3,Q96I36,P61313,Q15392,Q9UBM7,P16435 13 +Exaggerated startle response 0.4586948032793689 0.6786664975562557 0.4973491984274147 1.0 0.8463725456270004 9 P17900 1 +Facial hemangioma 0.5620081921379749 0.6782714099852742 0.4975996225628862 1.0 0.8463725456270004 5 Q9UBM7,P16435 2 +Constriction of peripheral visual field 0.3871150857035257 0.6766782895279696 0.4986100941591007 1.0 0.8472411673046338 21 O75381,Q9H061,O60313,P56589,Q6UX04,P40855 6 +Abnormal circulating phenylalanine concentration 0.5116605788142724 0.6766673857118791 0.4986170139005823 1.0 0.8472411673046338 2 P61457 1 +Hypoplastic fingernail 0.3992522753761674 0.6766080255287815 0.4986546857470837 1.0 0.8472411673046338 18 Q969G3,P21281,P51812,O75431,Q8TAQ2,Q14739,O60826 7 +Self mutilation 0.420088183008397 0.6756946839077806 0.4992345118789791 1.0 0.8479177649919802 14 Q9UBM7,Q9UM00,Q10713 3 +Abnormal middle phalanx morphology of the hand 0.5104598919029961 0.6740101395452047 0.5003048673545178 1.0 0.8494267002466341 7 Q9UHX1 1 +Transient global amnesia 0.5797506875005101 0.669902347691533 0.5029200430617424 1.0 0.8512821368754334 4 Q969G3 1 +Secondary growth hormone deficiency 0.5597981700387038 0.6696590120216741 0.5030751860837386 1.0 0.8512821368754334 5 Q969G3,O00255 2 +Abnormal circulating pyruvate family amino acid concentration 0.3888685541345473 0.6672801444527956 0.5045932067476437 1.0 0.8520599212675402 20 O75880,Q99797,O96000,P22695,Q9P0J0,Q9BUB7,P03886,Q5XKP0,Q9UJS0 9 +Aplasia hypoplasia of the uterus 0.4033122892751969 0.6657964241681764 0.5055412307990954 1.0 0.8520747867352861 17 O95202,Q16740 2 +Abnormality of the amniotic fluid 0.3059950814216111 0.6653571919767628 0.5058220582935924 1.0 0.8520747867352861 101 Q9UHX1,Q9NVI7,Q9BUB7,Q6NUK1,Q9UBM7,P23786,P21964,Q70HW3,Q96I36,P04062,Q6PGP7,Q969X5,Q9BT22,Q9UM00,P16435,Q7LGA3,O75844,O14656,Q14739,P02545,P40939 21 +Typical absence seizure 0.4262077754272788 0.6637178161581532 0.5068709342873423 1.0 0.8520747867352861 13 Q13510 1 +Sclerocornea 0.4414242775219965 0.6627530123343905 0.5074887516026816 1.0 0.8520747867352861 11 P53701,Q9UBM7,O95202,Q5H8A4 4 +Positional foot deformity 0.3027614159021716 0.6622952639606996 0.5077820114762308 1.0 0.8520747867352861 111 Q8NCH0,Q9NR77,P21964,Q9HC21,Q9NWM8,P02545,Q9UHX1,Q8TAA9,Q9UM00,Q6ZXV5,Q9NVI7,Q9UBM7,Q8TB36,O95202,Q15392,Q96A33,Q5H8A4,P16435 18 +Lower limb muscle weakness 0.3408355497502224 0.6620241223890453 0.5079557622616973 1.0 0.8520747867352861 45 O14908,Q969G3,Q9NR77,P07196,P53007,Q96T60,P02545,P37198,Q8IY17,O95140,Q12768,Q969X5,Q9Y4W6,Q13510,O43819,P40939,P04792 17 +Abnormal urinary electrolyte concentration 0.3849485398113775 0.6617553829635004 0.5081280045011964 1.0 0.8520747867352861 21 P05023,Q13423,P35670 3 +Anorexia 0.357085223885518 0.6606160229872381 0.5088585907624226 1.0 0.8520747867352861 30 Q14108,P04062 2 +Rib segmentation abnormalities 0.5573384566321604 0.6601011503908931 0.50918892051109 1.0 0.8520747867352861 5 Q5H8A4 1 +Abnormality of abdominal situs 0.5573384566321604 0.6601011503908931 0.50918892051109 1.0 0.8520747867352861 5 Q5H8A4 1 +Hypoplastic pubic rami 0.5573384566321604 0.6601011503908931 0.50918892051109 1.0 0.8520747867352861 5 Q5H8A4 1 +Increased susceptibility to fractures 0.339329025882359 0.6589153163916314 0.5099501498382066 1.0 0.8520747867352861 57 Q14108,P04062,P35670,Q14739,P16435 5 +Cataplexy 0.5765084779383802 0.6577749046933592 0.510682782248451 1.0 0.8520747867352861 4 O15118 1 +Thick nasal alae 0.4168003913544088 0.6569131369590389 0.5112367706958922 1.0 0.8520747867352861 14 Q969G3,P51812 2 +Allergic rhinitis 0.5068839561674504 0.6565087161051286 0.511496861307456 1.0 0.8520747867352861 2 O95394 1 +Beaking of vertebral bodies 0.4401047631814909 0.6559200421540115 0.511875571954926 1.0 0.8520747867352861 11 Q7RTS9,Q9UM00,P08236,P16278 4 +Widened subarachnoid space 0.3595925067684571 0.6548485977136977 0.5125652378553056 1.0 0.8520747867352861 29 Q01105,P51812,P03886,P00403 4 +Recurrent pneumonia 0.3839318308958743 0.6547611640124897 0.5126215384296648 1.0 0.8520747867352861 21 Q13432,P00813 2 +Abnormal lymphocyte morphology 0.338802228899469 0.6540275089714972 0.5130940827808446 1.0 0.8520771494657097 39 Q13432,O95470,P00813,P16278 4 +Protuberant abdomen 0.539595634876632 0.6520422066958362 0.5143739450537721 1.0 0.8534512968927015 6 P04062 1 +Abnormal myelination 0.301980443524146 0.6503680282955842 0.5154545241149369 1.0 0.8546367802175568 233 Q9NZJ7,P53007,P35670,Q8TAD8,P49589,Q9H490,Q5H8A4,Q99720,Q96RL7,Q5BJH7,O60508,Q96CU9,Q8WVX9,O43676,Q9Y6M9,O43681,O95140,Q8N183,Q8TB36,Q96I36,Q9Y3C6,P21912,Q9NWS8,P00374,O15121,P20700,Q2TAA5,O96000,Q86Y39,P51572,P03886,P51648,P10253,O75380,P00403,P41440,Q9NR77,P07602,Q96T60,Q7LGA3,Q9P0J0,Q8TB37,Q6ZXV5,P35637,P02545,O15269,Q9Y375,Q9NPL8 48 +Abnormality of dental color 0.5723531812695544 0.6498257491787308 0.5158047843834788 1.0 0.8549139291041755 3 P16278 1 +Abnormality of exocrine pancreas physiology 0.3858146753706659 0.6467177149951021 0.5178146557549661 1.0 0.8567245314386734 20 P09601 1 +Abnormal lower limb bone morphology 0.2947693994707576 0.6464084626739627 0.5180148612367541 1.0 0.8567521739689709 189 O43924,Q9NZJ7,Q10713,Q9UHX1,P13073,P16278,Q9UBM7,Q5H8A4,P21964,O95202,O00116,Q15392,Q96A33,P04062,Q7RTS9,Q13510,P16435,P07602,O43505,P51812,O75844,Q14739,P02545,P40939,P00813 25 +Horseshoe kidney 0.3391552159600879 0.6455557437793964 0.5185671064280992 1.0 0.8573618342467405 46 Q8NCH0,Q969G3,P18077,Q9UHX1,P51571,Q8TAQ2,P61313,P62847,P98175,Q6UX04,P16435 11 +Decreased circulating acth level 0.5374455284849993 0.6434645343795977 0.5199227203626551 1.0 0.858501089203446 6 Q969G3,O00255 2 +Abnormal oral mucosa morphology 0.3319409736521172 0.6427451034373297 0.5203895093331399 1.0 0.858501089203446 68 Q8N766,Q14108,P20700,P49257,P01889,P04062,O75431,Q9UM00,Q9Y4P3,Q15392,Q14739,P16278,Q9UBM7,P08236 14 +Gait disturbance 0.2969291869905009 0.6422985922390395 0.5206793281505446 1.0 0.858501089203446 340 O43924,Q14108,Q9NZJ7,Q15041,Q10713,P55795,Q9HC21,Q03252,P13473,P01889,Q9NVI7,P53007,P35670,O15118,P49589,P16278,O75477,P12235,Q99720,Q5H8A4,O14949,Q96RL7,P50402,Q8N766,Q969G3,Q96CU9,Q8WVX9,O75503,O43681,Q8TB36,P21912,Q5XKP0,Q9BTV4,Q92581,P20700,P04062,P82930,Q7RTS9,O15269,P03886,O43292,Q13510,P02545,P00403,P05023,O60313,Q9NR77,P41440,P07602,P51812,Q7LGA3,O75844,Q8TB37,Q9Y4P3,O14656,P35637,O14773,P05067,Q96N66,P40939,Q8IV08 61 +Abnormality of the calf musculature 0.3995229193388616 0.6422799130770872 0.520691454121031 1.0 0.858501089203446 17 Q9NR77,P02545 2 +Type i diabetes mellitus 0.437413230347937 0.6420126538507771 0.5208649669941656 1.0 0.858501089203446 11 P03886 1 +Increased intracranial pressure 0.3877162466198863 0.6411592799394505 0.5214192027526499 1.0 0.858501089203446 19 Q9NZJ7,P07602,P21912,P01889 4 +Abnormal greater sciatic notch morphology 0.5366401229160809 0.6402573843561957 0.5220052812856391 1.0 0.858501089203446 6 Q7RTS9,Q96HY6 2 +Hydrocephalus 0.3101249714403893 0.6401163630057943 0.5220969517585179 1.0 0.858501089203446 87 Q10713,Q8TAA9,Q6NUK1,Q9H490,Q9UBM7,P23786,O60508,Q969G3,P21964,Q15427,O95140,O95202,Q15392,P40855,P08236,P04062,P16435,O43505,P53701,O60826 20 +Laryngeal cleft 0.5029502669289082 0.640040429655184 0.5221463154152799 1.0 0.858501089203446 2 Q01082 1 +Female pseudohermaphroditism 0.5029502669289071 0.6400404296551793 0.522146315415283 1.0 0.858501089203446 2 P04150 1 +Central hypothyroidism 0.4369582831935722 0.6396660478685635 0.5223897330566625 1.0 0.858501089203446 11 P27635,Q969G3,O00255 3 +Aplasia hypoplasia of the capital femoral epiphysis 0.5519614807468178 0.6393125711157933 0.5226196120549187 1.0 0.858501089203446 5 Q7RTS9 1 +Hydrocele testis 0.5019014991594953 0.637225211021244 0.5239781581851373 1.0 0.858501089203446 7 Q9UBX3 1 +Broad columella 0.5514159370785436 0.6372116887351825 0.5239869649848226 1.0 0.858501089203446 5 Q6UX04,P36543 2 +Sparse eyebrow 0.3360818059405439 0.636710774510834 0.5243132540571498 1.0 0.858501089203446 37 O75844,P02545,Q9UM00,Q92643,P48449 5 +Abnormal glycosylation 0.3703150031392129 0.6361278603154502 0.5246930878853742 1.0 0.858501089203446 24 Q8N511,Q2TAA5,P46977,P51571,P36543,Q9H0U3,Q8TCJ2,Q9Y487,Q9BT22 9 +Difficulty standing 0.5016268979697217 0.6360512814348369 0.5247429980661167 1.0 0.858501089203446 7 Q7RTS9,O43292 2 +Degeneration of the lateral corticospinal tracts 0.5508872323896832 0.6351771486532065 0.5253128851264188 1.0 0.8587046194129825 5 P35637,Q12768 2 +Aplasia cutis congenita of scalp 0.5013736936869416 0.6349691877339347 0.5254485109579976 1.0 0.8587046194129825 7 Q5H8A4 1 +Areflexia 0.3062151116225763 0.633708880949746 0.5262708280294568 1.0 0.859632937289099 96 Q15041,P53007,P56589,O75477,P12235,Q96RL7,O95140,Q8TB36,Q9NWS8,Q969X5,P10253,Q13510,Q9BT22,O60313,P05023,P41440,Q9NR77,O43505,Q96T60,P02545,O15269,P40939 22 +Tetraplegia 0.4125596876452858 0.6327808552607507 0.5268767604780451 1.0 0.8601355226125849 14 Q13423,O43681,P51970,P51572 4 +Neurofibromas 0.5346582122456817 0.6323794320882937 0.5271389705510972 1.0 0.8602627939542372 6 P21912 1 +Broad philtrum 0.434640464765752 0.6277300279127047 0.5301808108687642 1.0 0.8633044470265502 11 Q969G3,Q9UM00 2 +Joint subluxation 0.5329066749138494 0.6254341600366441 0.5316861480070183 1.0 0.8635096609741589 6 Q9UHX1 1 +Ectopic anus 0.4017634469322285 0.6240817800650174 0.5325738788582091 1.0 0.8635096609741589 16 P49748,P53701,O60826,Q6NUK1,P16435 5 +Multiple lipomas 0.49824094976321 0.6216103998273853 0.5341980809275635 1.0 0.8639887662473719 7 Q8TAA9,O95140 2 +Coarse hair 0.3758195756338037 0.6216066893914529 0.534200521321383 1.0 0.8639887662473719 22 Q96A33,P54802,Q9UM00,P51812 4 +Atrophy degeneration involving the spinal cord 0.465158728341957 0.6215567581144334 0.5342333622095015 1.0 0.8639887662473719 8 Q13217,Q8IY17,P20700,P07196 4 +Retinal fold 0.4981736442820906 0.6202125556006153 0.5351178563705712 1.0 0.8648201008633426 2 P35222 1 +Type ii diabetes mellitus 0.3359480361315506 0.6189077655263031 0.53597712246951 1.0 0.8652152790713602 42 O76024,P49589,P03886,P02545,P00403 5 +Hyperphosphaturia 0.5465914586311948 0.6187019713355588 0.536112711097688 1.0 0.8652152790713602 5 P35670 1 +Heteronymous hemianopia 0.5311140676395418 0.6183428723142141 0.5363493467974703 1.0 0.8652152790713602 6 Q969G3,O00255 2 +Pituitary hypothyroidism 0.497441655884478 0.6182108561330979 0.5364363547920172 1.0 0.8652152790713602 7 Q969G3,O00255 2 +Abnormal sacrum morphology 0.3339945591436518 0.6175624918246538 0.5368637757631114 1.0 0.8652152790713602 37 P27635,P01889,Q8TAA9,P49711,Q9Y4P3,O95202,Q14739,P53701,Q9NX14,Q9UM00,Q5H8A4 11 +Abnormality of upper limb epiphysis morphology 0.3953917039078254 0.6167404995568357 0.5374059034910466 1.0 0.8652152790713602 17 O95202,P16435,P51812 3 +Abnormal pupil morphology 0.4170363849286314 0.613305686597995 0.5396742340216041 1.0 0.8676787185423104 13 Q9NR77 1 +Adrenocorticotropic hormone deficiency 0.5621536012345889 0.6122095129128935 0.5403991484403796 1.0 0.8681191096959289 3 O00255 1 +Abnormality of circulating enzyme level 0.3004422777597458 0.611996444294456 0.5405401100927076 1.0 0.8681191096959289 104 Q5JTV8,Q86VD7,P13473,P23786,P12235,Q96RL7,P50402,Q9NWM8,P09493,Q9BTV4,O43772,Q969X5,P42167,P49748,O43505,Q9HC07,Q6ZXV5,Q9Y4P3,P02545,P40939 20 +Alopecia totalis 0.5283658030787821 0.6075050254523199 0.5435158085657656 1.0 0.870296175770277 6 O75844 1 +Absent epiphyses 0.5283644307747954 0.6074996241603723 0.5435193919844501 1.0 0.870296175770277 6 Q7RTS9 1 +Abnormality of the parathyroid gland 0.3641978993710437 0.6072072172622746 0.5437134031817008 1.0 0.870296175770277 25 P00403,P40939,P03886,P35670 4 +Mixed hypo and hyperpigmentation of the skin 0.5434513007307702 0.6067233268361225 0.5440345388605257 1.0 0.870296175770277 5 P02545 1 +Dyskinesia 0.325171204556609 0.6033786798860779 0.5462568020603751 1.0 0.8720519099605355 72 Q5BJH7,Q9P0J0,P04062,Q01105,Q9UBX3,Q9NZ01,P03886,Q96N66,Q96RL7 9 +Pes valgus 0.4366682140453173 0.6031814129557942 0.5463880112644113 1.0 0.8720519099605355 10 Q9UHX1 1 +Megalocornea 0.4144624005859279 0.5992538912940971 0.5490035903244084 1.0 0.8735330285843118 13 O95202,Q5H8A4 2 +Molar tooth sign on mri 0.5413675904489667 0.5988057699294322 0.5493024142050844 1.0 0.8735330285843118 5 O43924 1 +Macrogyria 0.5248075029869568 0.5935356010602998 0.5528227647236601 1.0 0.8762562289854535 6 Q15392 1 +Broad phalanx of the toes 0.4586473940661761 0.5918083042918553 0.5539789617223319 1.0 0.8769837161065595 8 Q96T60,Q7LGA3 2 +Nocturnal seizures 0.4911491992132594 0.5914100367867381 0.5542457170441715 1.0 0.8769837161065595 2 Q01082 1 +Oculomotor nerve palsy 0.5241448705305927 0.5909422272628874 0.5545591311207594 1.0 0.8771126636865941 6 Q969G3,O00255 2 +Abnormality of the peripheral nervous system 0.2984342498685226 0.5893439712761767 0.5556305535787871 1.0 0.877813437178539 117 Q9NZJ7,Q10713,O76024,Q9UBM7,Q99720,Q96RL7,P21964,Q15427,O43681,O95140,Q8TB36,O15121,Q8N2K0,P20700,Q9NQZ5,P04062,O60313,P41440,Q9NR77,Q9Y619,P07602,P42892,Q96T60,P02545,Q13724,O15269 26 +Tongue fasciculations 0.4270759773614028 0.5890129497851219 0.5558525866446535 1.0 0.877813437178539 11 Q13510 1 +Abnormal endocardium morphology 0.4047421687052165 0.588599078631834 0.556130252125534 1.0 0.877813437178539 14 P04062,Q9Y4P3 2 +Abnormal circulating metabolite concentration 0.2879626387033413 0.5870273060850607 0.5571853677933107 1.0 0.8791816431993807 369 Q03252,P28288,P56589,P37268,Q8N511,Q96CU9,O43676,P49257,P12694,Q70HW3,Q9Y6B6,Q15392,P40855,O75880,P22626,O43772,O00255,Q86Y39,P03886,Q02978,O43819,Q9Y619,P07602,Q9HC07,O14979,O75844,Q15800,Q14739,Q9NX14,P40939,O95470,P14314,P07196,Q9NZJ7,Q9UGP8,Q86VD7,P35670,P22830,Q9NWM8,Q9Y6M9,P21912,Q5XKP0,O14874,Q9BT22,P42167,Q13423,Q9P0J0,Q6ZXV5,P02545,P13473,Q9NVI7,Q9BUB7,Q9UBM7,P23786,Q96RL7,P50402,P21964,P08574,Q16134,Q9BTV4,O96000,Q6PGP7,Q9BWD1,P05023,P49748,O43505,Q9Y4P3,Q9Y375,Q9NPL8,Q5JTV8,P12235,P09493,O14678,O75431,Q8N183,O75381,Q969X5,P10253,O75380,Q9UJS0,P61916,P41440,P22695,Q8TB37,P05067 85 +Adrenal hypoplasia 0.4568543797650708 0.5836647590144863 0.5594458815021768 1.0 0.8810314314720842 8 O75844,P02545 2 +Aplasia hypoplasia of the pubic bone 0.4890251031345771 0.5826437045499234 0.5601331777032132 1.0 0.8812179029038664 7 Q5H8A4 1 +Oral cleft 0.2890547670533034 0.5819285706018944 0.560614795056209 1.0 0.8813166592988013 180 O43924,Q10713,Q9HC21,Q9UHX1,Q8TAA9,P49589,Q9UBM7,Q5H8A4,Q8NCH0,P21964,Q12959,Q9NWM8,O95202,Q15392,Q6PGP7,P61313,Q9UM00,P16435,O43505,O75844,Q14739,P02545 22 +Abnormal conus terminalis morphology 0.4560945098533813 0.5802201186223437 0.5617661881040172 1.0 0.8825324132764658 8 Q5H8A4 1 +Functional abnormality of male internal genitalia 0.3368718719847879 0.5787808000559526 0.5627370878955111 1.0 0.8831662061795434 33 O76024,P04062,Q13423,P16435 4 +Abnormal skin morphology of the palm 0.3025367974136432 0.5782754054823414 0.5630781964320137 1.0 0.8832564557092724 95 P27635,Q9UHX1,Q6NUK1,P56589,Q06136,Q8NCH0,P62266,P09493,O75431,P49711,Q96I36,P21912,O95202,P40855,P16615,O75381,Q9H488,P42167,P51812,Q14739,P02545,P98175 22 +Kyphosis 0.2886160206239559 0.577394799816841 0.5636727862878226 1.0 0.883692503502299 171 Q14108,Q9UHX1,P16278,Q9UBM7,Q5H8A4,Q8NCH0,P50402,Q9NWM8,Q8TB36,P21912,O95202,Q9BTV4,P04062,Q7RTS9,P51648,Q9BT22,Q9NR77,P51812,Q9HC07,Q7LGA3,O75844,Q9Y4P3,Q14739,P02545,Q9Y375 25 +Progressive visual field defects 0.4872155099747027 0.5754757705358975 0.5649695726842117 1.0 0.8842919660954021 2 P35222 1 +Pulmonary interstitial high resolution computed tomography abnormality 0.5538778809786269 0.5747089700179522 0.5654881399238911 1.0 0.8843346990648874 4 Q13510 1 +Hypoplasia of the iris 0.5349532877896815 0.5745952114968965 0.5655650913274264 1.0 0.8843346990648874 5 O95202 1 +Developmental regression 0.2978054463771503 0.5742136593189956 0.5658232271853272 1.0 0.884442131813958 131 Q9NZJ7,Q8NI60,P55795,Q86VD7,P01889,O76024,P13073,P16278,O75503,O43681,P21912,Q92581,O75381,P82930,P03886,Q13510,P07602,Q9H078,Q9Y4P3,P17900,O14773,Q96IX5,O95470 23 +Focal dystonia 0.3568850312214211 0.5697513451213514 0.5688463598730149 1.0 0.8870425778923751 26 Q9NQZ5,Q99720,Q96RL7,O14656 4 +Delayed cranial suture closure 0.3357900953493506 0.5694279183576066 0.5690657749295056 1.0 0.8870425778923751 33 Q8NCH0,P51812,O75844,O75431,P02545,P16435 6 +Pectus excavatum 0.3059360131159844 0.5670772180188648 0.5706617203505129 1.0 0.8877837893205087 86 Q8NCH0,P50402,P51812,Q7LGA3,Q9UHX1,P04062,O75431,Q9Y4P3,P21912,P02545,Q9H490,Q96A33,Q9BTV4 13 +Generalized osteoporosis 0.5516936623688371 0.5668523720110487 0.5708144852087185 1.0 0.8877837893205087 4 P02545 1 +Long toe 0.4225366592359744 0.5659689034133396 0.571414919893821 1.0 0.8877837893205087 11 Q9UHX1 1 +Abnormal bronchus morphology 0.3585533562473085 0.5652954946153048 0.5718727926469707 1.0 0.8877837893205087 25 Q13432,Q96HY6,Q03518,Q03519,P16435 5 +Esophageal varix 0.5175245039325382 0.5651759571760213 0.5719540883007261 1.0 0.8877837893205087 6 P04062 1 +Narrow foot 0.4838437763416668 0.5619346255362249 0.5741605612955261 1.0 0.8880965533685689 2 O60828 1 +Premature birth 0.3307909724627376 0.5619173263619426 0.5741723481751566 1.0 0.8880965533685689 49 Q15427,O43676,O75381,O75844,P04062,Q9BUB7,Q9NX14,P02545,P56589,Q9UBM7,P40855 11 +Diplopia 0.3671581378626778 0.5612384657690979 0.5746349837096432 1.0 0.8880965533685689 22 P01889,P04062,O14773,P53007 4 +Redundant neck skin 0.4838616545493806 0.5610443958098602 0.5747672725216599 1.0 0.8880965533685689 7 O96000,Q9Y487,P36543 3 +Arthrogryposis multiplex congenita 0.3303629646224397 0.5599136547655165 0.575538334479075 1.0 0.8886205303183867 46 Q8NCH0,O75844,P04062,O14656,Q969X5,Q15392,P02545,Q92581 8 +Sporadic 0.3528670010898742 0.5577558064860546 0.577011144189564 1.0 0.8894239129155082 27 P51812,P04062,O95202,P21912 4 +Slender long bone 0.3989912383583749 0.5563805885530964 0.5779507059919529 1.0 0.89057816708793 14 P37268 1 +Exercise induced muscle cramps 0.5146484796087055 0.5540672551148044 0.5795328188769044 1.0 0.8913644405960379 6 P13473 1 +Abnormality of the diencephalon 0.3374617366588816 0.5534491390692369 0.5799558986633606 1.0 0.8913644405960379 32 O43924,Q969G3,Q9UPT5,Q9Y4P3 4 +Absent hair 0.4199935886420823 0.5531260871532289 0.5801770745150052 1.0 0.8913644405960379 11 O75844 1 +Abnormality of female external genitalia 0.3285998528287781 0.552276930710477 0.5807586336053618 1.0 0.8915575931601261 41 Q9Y619,Q6NUK1,O75381,P02545,P49711,P53701,Q15392,P56589,Q9UBM7,P16435,P40855 11 +Short clavicles 0.4198062249674859 0.5521818605623008 0.5808237609834634 1.0 0.8915575931601261 11 O75844,P02545 2 +Poor suck 0.3406030664250741 0.5518243551263985 0.5810686990760898 1.0 0.8915575931601261 31 P11047,P50542,P21281,Q12959,P53007,P22695,O75962,Q8TAQ2,O43819,Q9UBM7,P40939,O75306 12 +Abnormality of hair texture 0.3286430927208025 0.5509787861098207 0.5816482169892518 1.0 0.8921535890679424 58 P55795,P51812,O75844,Q9NVI7,Q9UM00,Q6PGP7,P49589,Q96A33,P54802 9 +Wormian bones 0.3792650463807441 0.5496665912105597 0.5825480755320025 1.0 0.8923612088775983 18 P07237,Q96AY3,P54886,O75844,Q9Y487,Q32P28,P02545,Q14696 8 +Premature graying of hair 0.4254125982443645 0.5478640718982265 0.583785240149419 1.0 0.8933770194223656 10 Q13126 1 +Tremor by anatomical site 0.3459209862855786 0.5454981842225409 0.5854109290195293 1.0 0.8933978278074703 29 Q9NR77,P20700,O95140,O14656,P35637,Q99720,Q96RL7 7 +Sparse or absent eyelashes 0.3535511073904942 0.5446593850646171 0.5859878033710526 1.0 0.8933978278074703 26 Q15427,O75844,Q14574,P02545,Q9UM00,P48449 6 +Hypoplasia of the frontal lobes 0.4181892159589458 0.5440444464863768 0.5864108877016128 1.0 0.8933978278074703 11 Q86XL3 1 +Dicarboxylic aciduria 0.3553467277298711 0.5416005257546922 0.5880937295707127 1.0 0.894639039817535 25 P49748,P53007,O43772,O14678,Q16134,P40939,P23786 7 +Delayed social development 0.5444710274872975 0.5410949049255904 0.5884421699035447 1.0 0.894639039817535 4 O60508 1 +Episodic ataxia 0.5250860155002273 0.5378599723556571 0.5906737244946365 1.0 0.8961840485765871 5 Q96T60,P09471 2 +Chorioretinal dysplasia 0.4774795878244665 0.5345986284118208 0.5929274322775901 1.0 0.8979494587428051 7 Q9NX14,P53701,O43505 3 +Delayed ability to walk 0.3171894475524429 0.5322784035456372 0.5945331876257325 1.0 0.899748646491796 74 Q10713,Q03252,P20700,P53007,P27635,Q86VD7,Q8WVX9,P82663,Q6UX04,Q6ZXV5,P35637,Q01105,P21912,Q5H8A4,Q96N66,Q99720,P48449 17 +Chronic constipation 0.3493727607771709 0.5310261625309143 0.595400649500414 1.0 0.9005266059337328 27 P55795,P20700,Q03252,Q8WVX9,Q7LGA3,P04062 6 +Tapered finger 0.3259127658802362 0.5306163068204471 0.5956846932354201 1.0 0.9006457529542855 40 P42892,Q06136,Q8NCH0,P51812 4 +Hyperconvex fingernails 0.5084620721334783 0.5303558595759077 0.5958652240042381 1.0 0.9006457529542855 6 P51812 1 +Abnormal circulating gonadotropin concentration 0.3940936926384598 0.5291556023742863 0.5966975125449334 1.0 0.9012647960594156 14 Q969G3,P51659,Q8IY17,P82650,P16435 5 +Expressive language delay 0.4151358003410167 0.528736442049771 0.5969882934783919 1.0 0.9012647960594156 11 Q9UHX1 1 +Aortic regurgitation 0.3490616836773832 0.5286519603125742 0.597046908162727 1.0 0.9012647960594156 27 O75844,Q9UHX1,Q6ZXV5,Q6PGP7,P02545 5 +Adrenal insufficiency 0.33775357194085 0.5282859169248088 0.5973009047436442 1.0 0.9013567951674448 31 Q13423,P50542,Q969G3,P51809,O75381,P51659,P82663,O00255,P33991,O00170,O95470,P56589,Q9Y2R9,P16435,P40855 15 +Absent facial hair 0.4211469158702087 0.5271509584613916 0.5980887617166353 1.0 0.9019376730915618 10 O75844 1 +Abnormality of circulating glucocorticoid level 0.3933972724223823 0.5253012538476117 0.5993737859090973 1.0 0.9024431494387536 14 Q13423,Q969G3,P16435 3 +Premature pubarche 0.5371836161055328 0.5229961812882925 0.6009769106740752 1.0 0.903234329083788 3 O00255 1 +Craniofacial dysostosis 0.5210098370493714 0.522876810580138 0.6010599829649452 1.0 0.903234329083788 5 Q6NUK1 1 +Angina pectoris 0.5391718561407818 0.522423702857304 0.6013753562255675 1.0 0.9034174833388592 4 O75844 1 +Failure to thrive in infancy 0.3221245242465136 0.5205215409857259 0.6027001181403948 1.0 0.9051163884199108 35 P40939,P37268,P49589 3 +Recurrent viral infections 0.3839155547142685 0.5182058277676942 0.6043146691275592 1.0 0.9067821981285888 16 Q13432 1 +Tissue ischemia 0.3636589585658739 0.5167720211016984 0.6053153134378242 1.0 0.9075841998847788 21 P02545,P01889,O75844,Q9Y4P3 4 +Abnormality of muscle size 0.2914398181586809 0.5135555345787718 0.6075627743456025 1.0 0.9091584786372996 210 Q10713,Q03252,P53007,Q9HC21,P13473,Q9NVI7,Q8TAD8,P49589,P16278,O75477,P12235,Q99720,Q6P4A7,Q96RL7,P50402,Q9NWM8,O95140,Q8TB36,Q15165,P21912,Q96A33,Q9BTV4,P51970,Q92581,Q8N2K0,Q6DKK2,Q969X5,P10253,Q13510,O60313,Q9NR77,O43505,P51812,Q96T60,Q7LGA3,Q13126,Q9Y4P3,P35637,P02545,O15269,Q9NPL8 41 +Irregular menstruation 0.4411621591189789 0.5133850237881517 0.6076820194845598 1.0 0.9091584786372996 8 O00255,O00170,P02545 3 +Peripheral axonal degeneration 0.305714106858865 0.5130404001746106 0.6079230606780144 1.0 0.9091584786372996 83 P41440,Q9NZJ7,P07602,Q9HC21,Q9NVI7,O60313,O95140,Q6DKK2,O76024,Q8TB36,P03886,P02545,P12235,O15269,Q96RL7,Q8IV08,P00403 17 +Eversion of lateral third of lower eyelids 0.4711997752177418 0.5121775071912845 0.6085267835870294 1.0 0.9094787300153138 2 P60953 1 +Monocytosis 0.4709187974149884 0.5110910466263093 0.6092873050229854 1.0 0.9097417419738788 2 Q9UJV9 1 +Abnormal monocyte morphology 0.4709187974149884 0.5110910466263093 0.6092873050229854 1.0 0.9097417419738788 2 Q9UJV9 1 +Atonic seizure 0.3598511013546543 0.5107886360920748 0.6094990673110661 1.0 0.9097669901775473 22 Q13510,Q01105 2 +Peripheral neuropathy 0.2856711606888301 0.5089018570238575 0.61082101824859 1.0 0.9098822978850282 183 Q9NZJ7,Q9NPL8,Q10713,Q15041,P53007,Q9HC21,P01889,Q9NVI7,P35670,O76024,P12235,Q96RL7,Q96CU9,O43681,O95140,Q8N183,Q8TB36,Q9NWS8,O15121,Q8N2K0,Q9Y2R0,P22626,P03886,P54802,P00403,P05023,P41440,Q9NR77,P07602,Q96T60,Q9P0J0,O60313,O15269,P40939,O95470,Q8IV08 36 +Cupped ear 0.3822890282154568 0.5086902215241695 0.6109693776020941 1.0 0.9098822978850282 16 Q15392 1 +Natal tooth 0.4711409099541055 0.5086271374726199 0.6110136034675795 1.0 0.9098822978850282 7 O75844 1 +Absent septum pellucidum 0.3213327036150956 0.507552918501923 0.611766915864139 1.0 0.909895062942596 36 O43505,Q9NZ01,P53701,O95202,Q15392,Q96N66 6 +Epiphyseal dysplasia 0.5023597077618711 0.5072254522217604 0.6119966383138331 1.0 0.909895062942596 6 Q9HC07 1 +Epidermal acanthosis 0.4169411647069868 0.5068776393446927 0.6122406759925034 1.0 0.909895062942596 10 Q06136 1 +Fever 0.2992528111027728 0.5064919378044085 0.6125113479947262 1.0 0.9098999312082012 89 Q9NR77,Q9NZJ7,P07602,Q9HC07,P03886,Q14739,Q13510,P00813,P00403 9 +Abnormal blood transition element cation concentration 0.3968916678754801 0.50468690066858 0.6137787629798059 1.0 0.9102439170683566 13 P61966,P28288,Q9Y276,Q6PGP7,P35670,O43819 6 +Abnormal paranasal sinus morphology 0.3458896307457676 0.504496337215131 0.6139126354354798 1.0 0.9102439170683566 27 Q03519,Q13432,Q9H0U3,Q03518,P00813 5 +Orchitis 0.53023397418674 0.4989879339721117 0.6177878843806435 1.0 0.9134895655417228 3 P01889 1 +Pleuritis 0.53023397418674 0.4989879339721117 0.6177878843806435 1.0 0.9134895655417228 3 P01889 1 +Neuroinflammation 0.53023397418674 0.4989879339721117 0.6177878843806435 1.0 0.9134895655417228 3 P01889 1 +Hepatoblastoma 0.4210571248122526 0.4988820111107518 0.6178625075992206 1.0 0.9134895655417228 9 Q969G3,Q6PGP7 2 +Abnormal protein glycosylation 0.3657862540310322 0.4985671603186709 0.6180843449343656 1.0 0.9135282704965346 19 Q8N511,Q9BT22,Q2TAA5 3 +Abnormality of the plantar skin of foot 0.3223352908005645 0.4974671633229704 0.6188596532604234 1.0 0.9138063634006692 40 P42167,P16615,P09493,P21912,P02545,Q06136 6 +Benign neoplasm of the central nervous system 0.3448868223242736 0.4968811956526581 0.6192728327806334 1.0 0.9138384501431028 27 O43924,P21912 2 +Decreased circulating gonadotropin concentration 0.53107697646245 0.4942953861876247 0.6210975830853731 1.0 0.9153739316368708 4 Q969G3 1 +Lactose intolerance 0.5283867341202995 0.492672426404095 0.6222440636721522 1.0 0.91677422949993 3 Q14566,P42345 2 +Episodic pain 0.3870205479305832 0.4902198759442475 0.623978317559188 1.0 0.9179117613364394 14 Q13423,P21912 2 +Heterotaxy 0.4975458736032004 0.4891710975663439 0.6247205697712446 1.0 0.9182886223112257 6 Q5H8A4 1 +Vertebral wedging 0.465018263557176 0.488479586387517 0.6252101815759088 1.0 0.9182886223112257 2 Q96AY3 1 +Thickened calvaria 0.406984552144809 0.4882669747587012 0.6253607505950249 1.0 0.9182886223112257 11 P16278,P51812 2 +Pericarditis 0.5111802717988498 0.4872434157735817 0.6260858415361839 1.0 0.9182886223112257 5 P01889,Q9NZ08 2 +Alopecia 0.3229164801767081 0.4869470446110286 0.6262958589309031 1.0 0.9182886223112257 47 P01889,O75844,P02545,Q06136,P00813,P48449 6 +Occipital meningocele 0.5101767475829506 0.4836469508044586 0.628636447930111 1.0 0.9198068240005288 5 Q10713 1 +Migraine 0.3452955980171993 0.4829760440532913 0.6291127459681263 1.0 0.9198133429597156 26 Q9NQZ5,P01889,P03886,O60313,P12235,P00403 6 +Abnormality of lower limb joint 0.2836717066147136 0.481963989939997 0.6298315273666173 1.0 0.9198133429597156 181 Q86XL3,Q9NZJ7,Q5JTV8,Q03252,Q15041,P53007,Q9UHX1,P49589,P16278,P37268,O75477,Q9UBM7,P23786,P21964,Q15427,O75431,O95140,Q96HY6,P21912,O95202,Q96A33,Q7RTS9,Q969X5,Q13510,P16435,Q9NR77,P07602,Q7LGA3,O75844,Q6ZXV5,Q9Y4P3,O14656,P02545 33 +Limited hip movement 0.3775389996813233 0.4810494685110663 0.6304813407085548 1.0 0.9198133429597156 16 Q7LGA3,O75844,P02545 3 +Anterior open bite malocclusion 0.4630514189378972 0.4810310795541268 0.6304944099186958 1.0 0.9198133429597156 2 P21281 1 +Focal motor seizure 0.3581081037299594 0.4796072013184463 0.6315067247744017 1.0 0.9198133429597156 21 Q01105,O75503 2 +Optic atrophy 0.2892994447784101 0.4776929059949588 0.6328687941872448 1.0 0.9208361758879888 209 Q9NZJ7,Q9HC21,P01889,Q9NVI7,Q9H061,O76024,P16278,P56589,Q9H490,Q9UBM7,Q5H8A4,Q8N766,Q96CU9,P21964,O43681,O95140,Q8N183,P50897,O95202,Q6P4Q7,Q5XKP0,P40855,Q8N2K0,O75381,P82930,Q86Y39,P51572,P03886,O43292,O75352,O43819,Q96TA2,P00403,P41440,P07602,O43505,P51812,Q8NHS3,Q9P0J0,Q6ZXV5,Q8TCJ2,O60826,O60313,Q13724,P98175 45 +Abnormal cry 0.3765817801204743 0.4755072730024751 0.6344254505387377 1.0 0.9221695824014672 16 Q13510,O60313 2 +Abnormality of fundus pigmentation 0.5253605695136843 0.4747339802911063 0.6349765947323656 1.0 0.9221695824014672 4 P38435 1 +Hypopigmentation of the fundus 0.5253605695136843 0.4747339802911063 0.6349765947323656 1.0 0.9221695824014672 4 P38435 1 +Abnormal circulating dicarboxylic acid concentration 0.3206190321877714 0.4744360563026617 0.6351889862932358 1.0 0.9221695824014672 42 P14314,P41440,P28288,O14678,P22695,Q16134,Q14739,P37268,Q9UJS0,P23786,P40855 11 +Gingival overgrowth 0.3368617616671105 0.4739207998255282 0.6355563861704236 1.0 0.9224161538793 29 Q8N766,P20700,Q9UM00,Q9Y4P3,Q14739,P16278,Q9UBM7 7 +Neurodegeneration 0.3417706524614378 0.4732876323458878 0.6360079844964877 1.0 0.9224980676030136 27 Q8NHS3,Q6DKK2,P35637,Q15165,P17900 5 +Delayed gross motor development 0.2908728843787703 0.4721152742337388 0.6368445106211178 1.0 0.9231103255644746 122 Q10713,Q03252,P53007,Q86VD7,Q01105,P49589,Q5H8A4,Q99720,P48449,Q5BJH7,Q8NCH0,O60508,Q8WVX9,P82663,P21912,P51970,P20700,P10253,Q7LGA3,Q9H078,Q6ZXV5,P35637,Q96N66 23 +Sound sensitivity 0.4316044255115324 0.4715592090231576 0.6372414481929929 1.0 0.9231103255644746 8 P17900 1 +Rib fusion 0.3972003378341798 0.471182426982502 0.6375104667325422 1.0 0.9231103255644746 12 Q9UM00,Q5H8A4 2 +Hypoplasia of the odontoid process 0.4618507998202786 0.4711381809867132 0.6375420610572933 1.0 0.9231103255644746 7 Q7RTS9,P16278 2 +Abnormality of the abdominal organs 0.2782556348317394 0.4708900839254058 0.6377192296064713 1.0 0.9231103255644746 386 Q14108,Q03252,P53007,P28288,P56589,Q01844,Q8N511,Q969G3,Q96CU9,O43676,P12694,O95140,P49711,Q9Y6B6,Q15392,P40855,P08236,P09601,O75880,P22626,O43772,P04062,Q86Y39,P03886,Q13510,P07602,Q9HC07,Q14739,P40939,Q9NZJ7,Q9HC21,Q9UHX1,P35670,O15118,P22830,Q5H8A4,Q8NCH0,Q9Y6M9,P21912,P00374,Q5XKP0,Q96A33,Q9BT22,P54802,P00403,P02545,P00813,P10619,Q10713,Q9NVI7,O76024,Q9BUB7,P16278,Q9UBM7,P23786,Q96RL7,P21964,Q16134,O95202,O96000,Q6PGP7,P49748,Q9H078,Q9Y4P3,Q9Y375,Q9NPL8,P01889,P12235,O43681,O75431,Q8N183,Q96HY6,Q96I36,Q9NWS8,O75381,P10253,O75380,Q9UJS0,P61916,Q8TB37 80 +Limb fasciculations 0.5237559741355029 0.4692899610490301 0.63886238996787 1.0 0.9235846996320484 4 Q16637,P04792,P55072 3 +Aplasia hypoplasia of the skin 0.3194501458949624 0.4691196205379533 0.63898413531183 1.0 0.9235846996320484 62 Q8NCH0,Q9NWM8,Q13126,O75844,Q6ZXV5,O95202,P53701,Q15392,P02545,Q5H8A4 10 +Abnormal ureter morphology 0.3170042947025402 0.4686660523065359 0.6393083558987769 1.0 0.9235846996320484 36 O75844,Q8TAA9,O76024,P02545,P23786 5 +Aplasia hypoplasia of the phalanges of the toes 0.52352206044237 0.4684980966623946 0.6394284317921619 1.0 0.9235846996320484 4 P02545 1 +Abnormal dentin morphology 0.5056906580335473 0.4676677388923443 0.6400222151124373 1.0 0.9235846996320484 5 Q5JRA6,Q96AY3,P50454 3 +Hyperreflexia 0.2934933878112786 0.4675095576461239 0.6401353556315459 1.0 0.9235846996320484 248 Q86XL3,Q9NZJ7,Q8NI60,Q10713,Q15041,P01889,P49589,P13073,P56589,O75477,Q99720,O14949,O60508,Q96CU9,Q8WVX9,P82663,O75503,O43681,O95140,Q8N183,Q9Y3C6,P21912,Q5XKP0,P40855,P20700,Q2TAA5,O75381,P04062,Q6DKK2,P82930,Q7RTS9,P03886,O43292,O60313,Q9NR77,P07602,Q9P0J0,Q8TB37,Q9H078,Q9Y320,Q9Y4P3,P35637,Q14739,P17900,O14773,Q96N66,Q96IX5 47 +Limited extraocular movements 0.4608779960522807 0.4672545482041844 0.6403177709807113 1.0 0.9235846996320484 7 P51659,O43819,O75306 3 +Central sleep apnea 0.4911591627305878 0.4654940148403826 0.6415777220317445 1.0 0.9236899118613058 6 Q96A33 1 +Absent eyebrow 0.4908668639895368 0.4644182116822639 0.6423481447133315 1.0 0.9238618349725592 6 O75844 1 +Eruption failure 0.4600700375257136 0.4640352984806977 0.6426224560532059 1.0 0.9238618349725592 7 O75844 1 +Persistence of primary teeth 0.4297161216231936 0.4633936396934469 0.6430822368089135 1.0 0.9238618349725592 8 O75844 1 +Cardiomegaly 0.3154311715091208 0.4607737262099361 0.6449609537262604 1.0 0.9253358946806676 35 P49748,Q07021,P13473,P04062,Q9Y4P3,P04066,Q14739,P10253,Q13724,P23786,P54802 11 +Fatigue 0.2962480617405356 0.4605857734867512 0.6450958203326356 1.0 0.9253358946806676 87 Q9NZJ7,P07602,P04062,Q70HW3,Q15165,Q14739,P21912 7 +Impaired vibratory sensation 0.3261926792852403 0.4588943173136817 0.6463100597629161 1.0 0.9262190512685868 32 Q9NR77,P20700,Q9Y619,Q8WVX9,O95140,Q9Y6B6,O14773,O43819,Q96RL7 9 +Palpitations 0.3692258300990527 0.4580927223040951 0.6468858272880926 1.0 0.9264861896595444 17 O00255,Q9BTV4,P12235,P21912 4 +Supraventricular arrhythmia 0.3734094481343261 0.457210405541108 0.6475198198852565 1.0 0.9264861896595444 16 P50402,Q9BTV4,P02545 3 +Recurrent respiratory infections 0.2896442070977773 0.456747527790356 0.6478525250591975 1.0 0.9264861896595444 139 Q9NZJ7,P53007,Q13432,P01889,Q03518,P16278,Q5H8A4,Q86YV9,Q969G3,P49711,O95202,P09601,P20700,P04062,Q7RTS9,P10253,Q13510,P54802,P07602,Q8N5M9,Q9Y4P3,O60826,P00813,Q03519,Q9NPL8 25 +Distal arthrogryposis 0.5023222984511069 0.4557780377289375 0.648549598642238 1.0 0.9264861896595444 5 Q8NCH0 1 +Skin ulcer 0.3186802821957542 0.4549016115324206 0.6491800234828957 1.0 0.9264861896595444 34 P01889,P04062,Q14739,P02545,Q8IZA0,O15269,Q03519 7 +Myalgia 0.3187486372496639 0.4539200086782305 0.6498864017085373 1.0 0.9264861896595444 43 P49748,P21964,P01889,P40939,P23786,Q14739,O60313,P02545,P12235 9 +Painless fractures due to injury 0.4557459960663084 0.4537697287049845 0.6499945735521186 1.0 0.9264861896595444 2 Q12756 1 +Abnormal qt interval 0.4107804876060202 0.4517449185424938 0.6514527546909397 1.0 0.9264861896595444 9 P49748,P40939,O00255 3 +Diminished motivation 0.3447753453649695 0.4511532809111464 0.6518790787798756 1.0 0.9264861896595444 24 P04062,P17900 2 +Abnormality of the middle ear 0.2884728245252502 0.4497766341050052 0.6528715075244393 1.0 0.9264861896595444 145 O43924,Q13432,P01889,Q9UBM7,Q5H8A4,P21964,Q12959,Q9NWM8,P21912,O95202,Q96A33,P16435,Q7LGA3,O75844,Q8N5M9,Q9Y4P3,Q14739,P02545,P00813 19 +Abnormality of the tonsils 0.4264291181277514 0.4492612500684461 0.6532432076160248 1.0 0.9264861896595444 8 P00813 1 +Wide mouth 0.3155002202253269 0.4471993059145294 0.6547311625007042 1.0 0.9274695988215376 66 Q969G3,P55795,P51812,Q7LGA3,P51571,Q9UM00,Q6PGP7,Q9Y4P3,Q9BUB7,Q8TAD8,Q01105,P16278,Q9H490,Q9UBM7 14 +Aplasia hypoplasia involving the pelvis 0.3625377316000368 0.4459800722052898 0.6556116407771448 1.0 0.927821138119596 18 O95202,O75431,Q5H8A4 3 +Neoplasm of the small intestine 0.4254546328989518 0.4450918554970745 0.6562533743535073 1.0 0.927821138119596 8 P21912 1 +Abnormality of earlobe 0.3331462165859089 0.4448286786229182 0.6564435675077127 1.0 0.927821138119596 29 P21964,Q7LGA3,P10586,P53701,Q9NX14,Q15392,P98175,P16435 8 +Abnormal scapula morphology 0.3184826641012287 0.4434743085715951 0.6574226981025679 1.0 0.9279040439664116 57 Q8TD16,P50402,Q9Y619,Q15427,P07196,P18077,P02545,Q7RTS9,Q9Y487,Q14739,Q15738,P61313,P62847,P62854,Q9UM00,Q9BTV4,P16435,O60313 18 +Micromelia 0.3466415239970535 0.4410783417620391 0.6591562823919346 1.0 0.928666470273972 23 Q9UHX1,Q14739,Q15392 3 +Steppage gait 0.3415019400031217 0.4404767583355543 0.6595918419017597 1.0 0.928774902074119 25 P05023,Q9NR77,O95140,Q8TB36,O15269,P02545,O43819 7 +Irregular femoral epiphysis 0.5123664980326099 0.4391403488629396 0.6605598443379894 1.0 0.929802204767583 3 P50542,Q9NUQ7 2 +Heterotropia 0.3174563386701073 0.4376252002650273 0.6616580002837968 1.0 0.9310672704415452 59 Q8N766,O43924,P55795,P20700,P53007,Q9UHX1,Q9NVI7,P82930,P04062,O43819,P40939 11 +Cranial nerve compression 0.3840445892177346 0.4373450526330962 0.6618611267452479 1.0 0.9310724919474428 13 P22626,O00255,P21912,Q02978 4 +Hyperhomocystinemia 0.5140765495227727 0.4369055923313408 0.6621798160794183 1.0 0.93124022929964 4 O14678 1 +Abnormal circulating follicle stimulating hormone concentration 0.4523929108114505 0.43374035685619 0.6644769970712356 1.0 0.9319399954932364 7 P16435 1 +Multifocal epileptiform discharges 0.326010171279487 0.4321872147315951 0.6656053509226214 1.0 0.9319399954932364 31 Q96N66,Q9UBX3,O75503 3 +Generalized joint laxity 0.3893078846991761 0.4315470789078293 0.6660706286058962 1.0 0.9319399954932364 12 Q9UHX1 1 +Aplasia hypoplasia of the scapulae 0.4950669398856272 0.4304969246501964 0.6668342033154806 1.0 0.9324919335978072 5 P16435 1 +High pitched voice 0.3759764145524407 0.4304552034771242 0.6668645462161229 1.0 0.9324919335978072 14 P07237,O75844,O75431,P02545 4 +Primary hyperparathyroidism 0.5105067731423133 0.4251671465025809 0.6707148319861753 1.0 0.936151975303019 4 O00255,P53680 2 +Diaphragmatic weakness 0.4794878728379728 0.4231000073661973 0.672222297009283 1.0 0.937328837875746 6 Q9NR77 1 +Enuresis 0.5071555469605645 0.4222348946414571 0.6728535738822581 1.0 0.9373410297795712 3 Q9UJS0 1 +Abnormal subarachnoid space morphology 0.3185703469557818 0.4221134651812083 0.672942200004524 1.0 0.9373410297795712 33 Q01105,P51812,P03886,P00403 4 +Abnormality of mouth size 0.2875431210689844 0.4181731860712511 0.6758204989292182 1.0 0.9393884815422804 131 P55795,Q9NVI7,P51571,Q01105,Q9BUB7,P16278,Q6NUK1,Q9H490,Q9UBM7,Q8NCH0,P21964,Q15392,P04062,Q6PGP7,Q9UM00,P16435,P51812,Q7LGA3,O75844,Q9Y4P3,P02545 21 +Agenesis of corpus callosum 0.289746301749438 0.4171138227686983 0.676595154812387 1.0 0.9398808777385786 97 Q86XL3,Q10713,O43505,Q9HC21,Q7LGA3,Q9UHX1,P03886,O95202,Q15392,P53701,P23786,Q5H8A4,P00403 13 +Food allergy 0.5071689626089337 0.4142955354555657 0.6786576830872544 1.0 0.9401898626184058 4 O95394,Q01082,Q9Y5S9 3 +Impaired tactile sensation 0.4179822930578725 0.4134446175741418 0.6792808908991359 1.0 0.9401898626184058 8 Q9NR77 1 +Lipoatrophy 0.3480492827670862 0.4131470042925844 0.6794989130923801 1.0 0.9401898626184058 21 P42167,P09493,O75431,P02545,Q6NUK1 5 +Disproportionate tall stature 0.3206144008090622 0.4126473068521869 0.6798650361149794 1.0 0.9401898626184058 32 Q8NCH0,Q9NWM8,O95202,Q5H8A4,P16435 5 +Caesarian section 0.5066413616020015 0.4125864526107656 0.679909628531991 1.0 0.9401898626184058 4 O60313 1 +Inflammatory abnormality of the eye 0.3130877930069879 0.4124335622128648 0.6800216676081294 1.0 0.9401898626184058 40 Q15800,P51648 2 +Multiple rows of eyelashes 0.5033726812816257 0.410127812366261 0.6817121915371187 1.0 0.9410403713150536 3 O60716,Q9Y2Z4 2 +Increased muscle lipid content 0.4014514603749459 0.4098811910984823 0.6818931035200007 1.0 0.9410403713150536 9 P23786 1 +Vertebral fusion 0.3848909344961904 0.4096704908419415 0.682047679702322 1.0 0.9410403713150536 12 Q9UHX1,Q8TAA9 2 +Aplasia hypoplasia affecting the fundus 0.3305741219572807 0.4060702014120584 0.6846910198552871 1.0 0.9421602440675791 28 P37268,Q9UHX1 2 +Abnormality of the liver 0.2873830481558145 0.405914120890478 0.684805702174839 1.0 0.9421602440675791 331 Q14108,Q03252,P53007,P28288,P56589,Q01844,Q8N511,Q969G3,Q96CU9,O43676,O95140,P49711,Q9Y6B6,P40855,P08236,P09601,O75880,P22626,O43772,P04062,Q86Y39,P03886,Q13510,Q9Y619,P07602,Q9HC07,Q14739,Q9NX14,Q13724,P14314,P40939,Q8WWI5,Q9NZJ7,Q9UGP8,Q9HC21,P35670,Q9H0U3,O15118,Q8TAQ2,P22830,Q5H8A4,Q07021,Q9Y6M9,Q8IY17,P33991,P14927,P04066,P21912,P00374,Q9Y4L1,Q5XKP0,Q96A33,Q9Y285,Q9BT22,P54802,P02545,P00813,P10619,Q10713,Q9NVI7,Q9BUB7,P16278,Q9UBM7,P23786,Q96RL7,P21964,Q16134,O95202,O96000,Q6PGP7,P49748,Q9H078,Q9Y4P3,Q9Y375,Q9NPL8,P12235,O43681,O75431,Q8N183,Q96HY6,Q96I36,Q9NWS8,O75381,P10253,O75380,Q9UJS0,P61916,Q8TB37 88 +Abnormal urine phosphate concentration 0.4745539301613339 0.4055421556786103 0.6850790380401437 1.0 0.9421602440675791 6 P35670 1 +Prominent superficial blood vessels 0.3839159873509924 0.4048730178014275 0.6855708528145992 1.0 0.942260357245868 12 O75844,P02545 2 +Lipid accumulation in hepatocytes 0.3077363504714714 0.4046194354727928 0.6857572700624244 1.0 0.942260357245868 72 Q8N511,O75880,P49748,Q03252,O43772,O75431,Q16134,P35670,Q9H078,P40939,Q9Y6B6,Q9NWS8,P02545,Q5XKP0,Q9UJS0,P23786,Q9Y375 17 +Abnormal pattern of respiration 0.2815989789928564 0.40293650090661 0.686994938428952 1.0 0.9434056963308168 191 O43924,Q9NZJ7,Q10713,P53007,P01889,Q9UHX1,P51571,O76024,P23786,P12235,Q86TI2,Q96CU9,O14678,Q16134,Q8N183,Q15165,Q96A33,P51970,O75880,O43772,P04062,Q86Y39,P03886,Q969X5,P10253,Q13510,O75380,O43819,O60313,P49748,Q9Y619,P07602,P51812,P22695,O75844,Q9P0J0,P35637,Q8TCJ2,Q9NX14,P53701,P02545,Q13724,P98175 43 +Abnormality of the antitragus 0.5008496822280519 0.4021322935090258 0.6875866674807929 1.0 0.9438989208026548 3 Q92643 1 +Ectropion of lower eyelids 0.4411351503231225 0.4012824005006757 0.6882122196277252 1.0 0.9438989208026548 2 O60716 1 +Talipes equinovarus 0.2913759176069908 0.4008157276518154 0.6885557985822297 1.0 0.9438989208026548 88 Q8NCH0,Q9NR77,P21964,Q9HC21,Q9NWM8,Q8TAA9,Q9UM00,Q6ZXV5,Q8TB36,O95202,Q15392,Q96A33,Q5H8A4,P16435 14 +Infantile muscular hypotonia 0.3058076247128258 0.4008003978583239 0.6885670859399962 1.0 0.9438989208026548 74 Q9NZJ7,Q969G3,P49748,Q2TAA5,P07602,P27635,Q96T60,Q13724,Q8TAQ2,P03886,P10253,P16278,Q13510,P17900,O43819 15 +Cutaneous cyst 0.4859116288134021 0.3992722526453063 0.6896926099971699 1.0 0.9441259455610408 5 Q8TAA9 1 +Ambiguous genitalia 0.3357372281854147 0.3990554341617137 0.6898523589089351 1.0 0.9441259455610408 25 Q9UBM7,Q8TAA9,P16435,Q15392 4 +Velopharyngeal insufficiency 0.4726576948589484 0.3988548710719952 0.6900001433744523 1.0 0.9441259455610408 6 Q12959 1 +Onset 0.2649754644323076 0.3984403569616487 0.6903056146339019 1.0 0.9441259455610408 429 O43924,Q03252,P28288,Q53H12,Q969G3,Q96CU9,P22466,Q8WVX9,P82663,O95140,Q70HW3,Q9Y6B6,P50897,Q8N2K0,P04062,Q14574,Q13510,O75352,O43819,Q96TA2,Q9NR77,P07602,P18077,O14979,P35241,Q8TCJ2,Q9NX14,O14773,Q13724,Q96N66,P40939,P14314,P38435,P07196,Q9NZJ7,Q9UGP8,Q99797,Q9HC21,Q9UHX1,O15118,P22830,Q5H8A4,Q5BJH7,Q9Y6M9,P21912,Q5XKP0,Q9NQZ5,O43292,P54802,P46977,Q9P0J0,Q6ZXV5,Q9Y3A4,P02545,Q92643,Q8IV08,Q10713,Q9NVI7,O76024,Q9BUB7,P16278,Q9H490,P23786,P50402,P08670,Q8TB36,Q9BTV4,P51970,Q2TAA5,P49748,O43505,Q7LGA3,Q8NHS3,Q9H078,Q9Y320,Q9Y375,Q9NPL8,P55795,P51571,Q6NUK1,P12235,O60508,O14678,O75431,Q9NWS8,P20700,Q969X5,P61916,P41440,Q96T60,Q8WWV3 91 +Microdontia 0.331769988263797 0.3983796019641524 0.6903503915496665 1.0 0.9441259455610408 27 P07237,Q7LGA3,Q9UM00,P49711,Q9Y4P3,Q6NUK1,Q96A33 7 +Broad chin 0.4400112391121136 0.3973638587372086 0.6910991627932384 1.0 0.9442735900966444 2 P55011 1 +Aplasia hypoplasia of the eyebrow 0.3135166176464526 0.3959575436289423 0.6921363491359063 1.0 0.9443889367203416 47 Q15427,O75844,Q9NVI7,O75431,Q14574,P02545,P00813,Q9UM00,Q92643,Q6UX04,Q14696,P48449 12 +Emg myopathic abnormalities 0.3154078921005204 0.3954634792989041 0.692500868970475 1.0 0.9443889367203416 33 P50402,P53007,P22626,P13473,Q9Y6B6,P02545,P12235,Q9BTV4 8 +Acetabular dysplasia 0.3977207892526166 0.3934108846510961 0.6940160316744608 1.0 0.9452627922660612 9 Q969X5,P16278 2 +Abnormal heart valve physiology 0.2893854604441881 0.3889897107030897 0.6972837578406699 1.0 0.9475022891030522 92 P01889,Q9UHX1,Q8TAD8,P16278,Q6NUK1,Q86TI2,Q8WVX9,P09493,O75431,P04062,Q6PGP7,P51812,O75844,Q6ZXV5,Q9Y4P3,P53701,O60826,P02545,P40939,P00813 20 +Ureterocele 0.469690872905354 0.3884614383254727 0.6976745855683533 1.0 0.9476521637856968 6 Q96T60,Q9H936,P09471 3 +Cholecystitis 0.391242023749728 0.3867591863835402 0.6989344948426202 1.0 0.9476521637856968 10 P07602 1 +Hypoplastic facial bones 0.3643603538743929 0.3857191205150188 0.6997047005198191 1.0 0.9483080542023324 15 Q7RTS9,P16435,Q9Y4P3 3 +Abnormality of the clitoris 0.341294248346815 0.3852767310759442 0.7000323993195683 1.0 0.9484756798032262 22 Q9Y619,O75381,P40855,P53701,P56589,Q9UBM7,P16435 7 +Abnormal cranial nerve physiology 0.2939881452335563 0.3822011953498643 0.7023121352614012 1.0 0.95035635502365 84 Q9NZJ7,P53007,P01889,Q9UHX1,P56589,P12235,Q969G3,P21912,P40855,O75381,O00255,Q92796,Q13510,O43819,Q96TA2,Q9NR77,P07602,P51812,P02545 19 +Abnormality of limb epiphysis morphology 0.3168914157489388 0.3820324356522092 0.7024373058870457 1.0 0.95035635502365 32 Q7RTS9,O95202,P16435,P51812 4 +Basal ganglia cysts 0.4662477210377612 0.3765078917877493 0.706539349597882 1.0 0.9530305245883656 6 Q96RP9,P37198,P23786 3 +Abnormal basophil morphology 0.4338297274515326 0.3761313262998326 0.7068192663902839 1.0 0.9530305245883656 2 Q01130 1 +Anhidrosis 0.4661095698416196 0.376030750915293 0.7068940349681287 1.0 0.9530305245883656 6 P04066,P20700 2 +Delayed ability to roll over 0.465892825825634 0.3752825583839312 0.70745033624143 1.0 0.9530305245883656 6 Q5BJH7,P51970 2 +Aplasia hypoplasia of the distal phalanges of the hand 0.3089009047195278 0.3743137419438297 0.7081709093998607 1.0 0.9531523865947336 40 P51798,Q969G3,P51812,Q8IWS0,O75844,Q92796,O60826,P02545,Q6NUK1,P38435,Q6UX04,P16435 12 +Prenatal movement abnormality 0.3087385484946537 0.3739029806275502 0.7084764988134022 1.0 0.9531523865947336 66 P53007,Q9HC21,O75844,P04062,Q9UM00,O14656,Q70HW3,O95202,Q969X5,P02545,P56589,Q9UBM7,Q5H8A4 13 +Abnormal reflex 0.2748655919044173 0.3702826512372441 0.7111718989270377 1.0 0.9536075807266912 383 Q86XL3,Q9NZJ7,Q8NI60,Q10713,Q15041,P53007,Q9HC21,P01889,Q8TAA9,Q8TAD8,P49589,P13073,P56589,O75477,P12235,Q99720,Q5H8A4,O14949,Q96RL7,P50402,O60508,Q8N766,Q96CU9,Q8WVX9,P82663,O75503,O43681,O95140,Q8N183,Q8TB36,Q9Y6B6,Q9Y3C6,P21912,Q9NWS8,Q5XKP0,O15121,Q9BTV4,P40855,P20700,Q2TAA5,O75381,P04062,Q6DKK2,P82930,Q7RTS9,O15269,P03886,O43292,Q969X5,Q13510,P10253,Q9BT22,P02545,P54802,O60313,P05023,P41440,Q9NR77,P07602,O43505,P51812,Q96T60,Q9P0J0,Q8TB37,Q9H078,Q9Y320,Q9Y4P3,P35637,Q14739,P17900,O14773,Q96IX5,Q96N66,P40939 74 +Recurrent 0.4903201377180798 0.3694746495411324 0.7117739652880868 1.0 0.9541408681969789 3 P12694 1 +Abnormality of complement system 0.4927399189275725 0.3685156368099178 0.7124887877856478 1.0 0.9543362153897096 4 P02545 1 +Vertebral segmentation defect 0.3151620616382853 0.367886997971378 0.7129574955339608 1.0 0.9546310715939385 32 Q9UHX1,Q8TAA9,O95202,Q9UM00,P16435 5 +Abnormality of pain sensation 0.3230642004656688 0.3668406166464618 0.7137379088393023 1.0 0.9550635721142968 29 Q8NCH0,Q9NR77,Q8WVX9,O00255,O95140,O15269 6 +Slowly progressive 0.3093801145665417 0.3666311530867754 0.7138941672047325 1.0 0.9550635721142968 63 P05023,Q5JTV8,P50402,Q8N2K0,P41440,Q9NR77,P02545,O14979,Q9P0J0,O95140,O14773,Q9BTV4,P12235,Q99720,Q8IV08 15 +Gastrointestinal inflammation 0.3378865660636739 0.3627303291343941 0.7168063411917864 1.0 0.9570019956375534 22 P08183,P49748,Q6PGP7 3 +Hyperreflexia in upper limbs 0.4334312629994052 0.3614108454037415 0.7177923416853491 1.0 0.9575349838082556 7 P21912 1 +Distal lower limb amyotrophy 0.3597554658178318 0.3609422285437439 0.718142634668455 1.0 0.9577286378940348 15 Q8TD16,O14908,Q9NR77,O95140,Q9H0B6,P02545,P07196 7 +Aplasia hypoplasia involving the skeletal musculature 0.3897734526652698 0.3588837507921388 0.7196820559701949 1.0 0.958825264766664 9 Q9NR77 1 +Abnormality of the fetal cardiovascular system 0.4605201269068006 0.3568903369518961 0.7211739039426701 1.0 0.958825264766664 6 P16435 1 +Short digit 0.2748270892620161 0.3568722557633761 0.7211874405626895 1.0 0.958825264766664 174 O43924,Q9UHX1,P13073,Q06136,Q9UBM7,Q5H8A4,P48449,O95202,P21912,Q7RTS9,P61313,Q13510,P16435,P51812,O75844,Q14739,P02545,Q92643,P00813,P38435 20 +Abnormal aortic valve physiology 0.3085545804146906 0.3554859692421611 0.7222255543516525 1.0 0.958825264766664 44 P01889,O75844,Q9UHX1,P04062,Q6PGP7,Q6ZXV5,Q9Y4P3,O60826,P16278,P02545 10 +Abnormal blood glucose concentration 0.2830076976300571 0.3545338850462524 0.7229388143885973 1.0 0.958825264766664 102 P23786,Q96CU9,O43676,Q9Y6M9,P12694,Q16134,Q8N183,Q5XKP0,O75880,O43772,O96000,Q86Y39,P03886,O75380,Q13423,P49748,P22695,O75844,Q8TB37,Q9H078,Q9Y375,P02545,P40939,O95470,Q9NPL8 25 +Hypoplastic fifth fingernail 0.4314706434609367 0.3541533968977634 0.7232239269241001 1.0 0.958825264766664 7 Q969G3 1 +Diabetes insipidus 0.3669936029859677 0.3509562067569046 0.7256212031172313 1.0 0.9609777396298635 13 O76024 1 +Short ribs 0.383076237315158 0.3501817737879435 0.7262022842704283 1.0 0.9609777396298635 10 Q96HY6,Q14739,Q15427 3 +Hypoplastic labia majora 0.3754992525490429 0.3385827876257747 0.7349240509943646 1.0 0.9685675433188377 11 Q6NUK1,P16435,P49711 3 +Abnormal labia majora morphology 0.3754992525490429 0.3385827876257747 0.7349240509943646 1.0 0.9685675433188377 11 Q6NUK1,P16435,P49711 3 +Aplasia involving bones of the extremities 0.4828943625159954 0.3384849887984084 0.7349977374228693 1.0 0.9685675433188377 4 P02545 1 +Preaxial hand polydactyly 0.3753682911168876 0.337986240277639 0.7353735569229043 1.0 0.9685675433188377 11 Q9UHX1,Q5H8A4 2 +Constipation 0.2803329138768159 0.3375106251774923 0.7357320038297779 1.0 0.9687345532659992 105 Q8NCH0,Q13423,P55795,P21964,P20700,P42892,Q7LGA3,P04062,Q8TAA9,Q9Y4P3,O76024,P03886,P21912,P37268,Q9UBM7,P12235,P16435,P00403 18 +Cholestasis 0.2976651090450524 0.3367342749889903 0.7363172230685486 1.0 0.969064112148196 77 P61916,P49748,O75381,Q9UJS0,P28288,Q16134,P49711,P35670,O15118,Q9UBM7,Q6PGP7,Q14739,P00374,P56589,Q13510,P40939 16 +Hypoplasia of the corpus callosum 0.2802292405796944 0.3363869586549139 0.7365790825707401 1.0 0.969064112148196 202 O43924,Q9NZJ7,Q9UHX1,P51571,Q01105,P49589,Q6NUK1,Q9H490,P37268,Q9UBM7,Q5H8A4,P48449,Q5BJH7,Q9NZ01,Q9NWS8,P04062,P03886,Q9UM00,P00403,P07602,Q7LGA3,Q9Y320,Q6ZXV5,Q9UBX3,Q96N66 25 +Hypoplastic fifth toenail 0.3990993526597278 0.3362851653339101 0.736655835547176 1.0 0.969064112148196 8 O14497,Q969G3,P51532,Q8TAQ2,Q92785,Q12824,Q96GM5 7 +Hallux valgus 0.351829390807203 0.3360773904387367 0.7368125076303482 1.0 0.969064112148196 16 P04062,Q15427,Q9Y4P3 3 +Esodeviation 0.3054994025649271 0.334467160568578 0.7380270674798861 1.0 0.9695194606854908 42 O43924,Q9UHX1,P04062 3 +Atrophy degeneration affecting the brainstem 0.3547364437757575 0.3342907959165429 0.7381601351416416 1.0 0.9695194606854908 15 O15121,Q13813,P20700,O60313 4 +Cogwheel rigidity 0.4811744139094758 0.3333449316203149 0.7388739263824957 1.0 0.9695194606854908 4 P12235 1 +Abnormal sternal ossification 0.4811643726644008 0.3333150182172504 0.7388965040409694 1.0 0.9695194606854908 4 O95202 1 +Abnormal leukocyte physiology 0.3041476426644854 0.3297801058966807 0.7415661204279227 1.0 0.9710822983348152 67 P09601,Q14108,P21964,P04062,P02545,P00813 6 +Gastroesophageal reflux 0.2816670842877057 0.3292320556532086 0.7419802953805634 1.0 0.9710822983348152 130 Q9UGP8,Q9NZJ7,P55795,P53007,Q9UHX1,P51571,Q01105,Q6NUK1,Q9UBM7,P12235,Q86TI2,P21964,O14678,P49711,O95202,Q96A33,Q92581,O00255,P82930,Q8IZA0,P16435,P49748,Q9Y619,P07602,Q6ZXV5,Q9Y4P3,Q14739,O60826,O15269,P14314 30 +Axonal regeneration 0.479074579249357 0.3271135401354316 0.7435820111391365 1.0 0.9710822983348152 4 Q8TB36 1 +Contractures involving the joints of the feet 0.3269534055069507 0.3266385395642495 0.7439412906519487 1.0 0.9710822983348152 24 P50402,Q8IZA0,Q9BTV4,P02545 4 +Upper limb asymmetry 0.4186569261028428 0.3264193966646418 0.7441070641005427 1.0 0.9710822983348152 2 Q15555 1 +Abnormal circulating methionine concentration 0.4510651510123238 0.3252710946387604 0.7449759055589609 1.0 0.9715900846521756 6 Q6PGP7 1 +Rigidity 0.3067698567039753 0.3242658409359956 0.7457367786364144 1.0 0.971903396962602 57 Q9NZJ7,P07602,P04062,P16278,Q15392,P12235,Q9Y287 7 +Abnormality of mouth shape 0.299020259449126 0.3231119438171266 0.7466104651572456 1.0 0.971903396962602 74 Q86XL3,Q10713,P51812,P04062,Q9H490,Q96A33,Q5H8A4 7 +Attenuation of retinal blood vessels 0.3957222022303909 0.3229549425274935 0.7467293656993801 1.0 0.971903396962602 8 Q96S66,P38435,O43837 3 +Abnormal hair laboratory examination 0.3812358608586369 0.3227045556944475 0.7469190016482743 1.0 0.971903396962602 9 P02545 1 +Cerebral hemorrhage 0.3524882836162476 0.3224793368763079 0.7470895891408822 1.0 0.971903396962602 15 P05067,Q969G3,P23786,P21912 4 +Motor polyneuropathy 0.3609169665132568 0.321139410520528 0.7481047454480767 1.0 0.9724112072653311 13 Q15041,P53007,P36551,P50336,O43819,P07196 6 +Auditory hallucinations 0.4166900814835673 0.3202371778918884 0.7487885420555205 1.0 0.9727584036887104 2 P19022 1 +Abnormality of iron homeostasis 0.4612988825887292 0.3194864543930474 0.7493576614488522 1.0 0.973179309081068 5 P28288,Q6PGP7 2 +Retinal coloboma 0.3803601203123828 0.319050223090535 0.7496884287522283 1.0 0.973179309081068 9 Q9UHX1 1 +Nonprogressive 0.4215517591175102 0.3181325975721661 0.7503843578247162 1.0 0.973179309081068 7 Q9NQZ5 1 +Peripheral axonal neuropathy 0.3030628227965675 0.3180625998763395 0.7504374525682098 1.0 0.973179309081068 67 Q9NZJ7,P07602,Q9HC21,Q9NVI7,O76024,Q8IV08,P03886,O60313,Q96RL7,P00403 10 +Eeg with focal epileptiform discharges 0.3036405748854375 0.3175099956497625 0.7508566561307439 1.0 0.973179309081068 42 Q96N66,Q9UBX3,O75503,Q5H8A4 4 +Myoglobinuria 0.3708008778273537 0.3173362881703735 0.750988445195778 1.0 0.973179309081068 11 P40939,P23786 2 +Pigmentary retinopathy 0.3058853219644522 0.3145498820672282 0.75310343706897 1.0 0.9741562985192728 52 Q9UG56,Q8NHS3,Q9P0J0,O76024,P03886,P21912,Q96S66,P53701,P40939,P00403 10 +Polymicrogyria 0.2907726474079091 0.314108096946129 0.753438940068119 1.0 0.9741562985192728 82 Q10713,Q15427,O43505,O75381,Q9Y320,Q6ZXV5,Q01105,Q9NZ01,Q15392,P56589,P37268,Q96N66,P23786,P40855 14 +Premature skin wrinkling 0.3326069129575565 0.3138694883216011 0.7536201649714314 1.0 0.9741562985192728 21 Q6NUK1,O75844,P02545 3 +Recurrent ear infections 0.4710511523327793 0.3128836321324438 0.754369073362539 1.0 0.9743151323733594 3 P39656,Q01082 2 +Lower limb amyotrophy 0.3357123960666953 0.3114803486982229 0.7554354798533953 1.0 0.9743519010098972 19 O14908,Q9NR77,Q9NVI7,O95140,Q9H0B6,P02545,P07196 7 +Abnormal ureter physiology 0.3052516456872692 0.3107393442404877 0.7559987845026788 1.0 0.9743519010098972 50 Q86XL3,P21964,Q9UHX1,Q8TAA9,P21912,Q9UBM7,P16435 7 +Hypermethioninemia 0.4583916332905199 0.3104980829933295 0.756182217050299 1.0 0.9743519010098972 5 Q6PGP7 1 +Abnormal odontoid tissue morphology 0.3044371594580652 0.3092153301507906 0.7571577331869608 1.0 0.9749502085631327 47 P21964,Q9HC07,Q9Y4P3,P51648,Q6P4Q7,Q9UBM7,P16278 7 +Acantholysis 0.4576224882153882 0.3081364812550404 0.7579784828210365 1.0 0.9756777837222612 5 P16615 1 +Abnormality of humoral immunity 0.3045298793546394 0.3067098649455168 0.7590642203324816 1.0 0.9756777837222612 60 P09601,Q14108,P04062,P02545,P00813 5 +Congenital onset 0.2801279213024269 0.3060015041940589 0.759603500499126 1.0 0.9756777837222612 130 O43924,Q9NZJ7,Q9HC21,Q9UHX1,P51571,Q9BUB7,Q6NUK1,P12235,Q5H8A4,O60508,Q5BJH7,P08670,O14678,Q5XKP0,P07602,O43505,P46977,Q7LGA3,Q9H078,Q9Y3A4,Q96N66 21 +Glaucoma 0.2825642329722811 0.3033378934464812 0.761632370914834 1.0 0.9772652690224072 93 Q86XL3,Q8NCH0,P21964,O43505,O75381,P18077,Q6PGP7,Q9Y4P3,O76024,Q53H12,P53701,P61313,O60826,P56589,Q06136,Q9UBM7,P12235,P40855 18 +Sprengel anomaly 0.3042934413671471 0.3031454897949285 0.7617789883043478 1.0 0.9772652690224072 33 P50402,Q9UM00,P61313,P02545 4 +Abnormality of toe 0.2775599134230023 0.30281266689746 0.7620326295858528 1.0 0.9772652690224072 198 O43924,Q10713,Q9UHX1,P13073,P37268,Q9UBM7,P23786,Q5H8A4,Q99720,P21964,Q8TB36,Q96A33,P04062,Q13510,Q9UM00,Q9NR77,P51812,O75844,Q14739,P02545,P00813 21 +Elevated circulating aspartate aminotransferase concentration 0.3623340187086277 0.3019343249667012 0.762702128613804 1.0 0.9772652690224072 12 P40939 1 +Severe postnatal growth retardation 0.3673450365797774 0.3019186236274102 0.7627140982707932 1.0 0.9772652690224072 11 O76024,O95202 2 +Short chin 0.3510485965223668 0.3013278046884822 0.7631645405573229 1.0 0.9772943609056886 14 O75844 1 +Sparse and thin eyebrow 0.3613093687196368 0.2972177786919864 0.766300249411449 1.0 0.9805031144154716 12 P48449 1 +Breast aplasia 0.467737593665893 0.2943294364349261 0.768506181291075 1.0 0.9821977068011002 4 P02545 1 +Abnormality of prenatal development or birth 0.2854282057882052 0.2938312795636053 0.7688868319464599 1.0 0.9821977068011002 267 P10619,P53007,Q9HC21,Q9UHX1,Q8TAA9,Q9NVI7,O15118,Q9BUB7,P16278,P56589,Q6NUK1,Q9UBM7,P23786,Q5H8A4,Q96CU9,P21964,Q15427,O43676,Q9Y6M9,P49711,Q70HW3,Q8N183,Q96I36,O95202,P40855,P08236,O75381,O43772,O96000,P04062,Q86Y39,Q6PGP7,P03886,P61313,Q969X5,Q13510,O75380,Q9BT22,Q9UM00,P16435,O60313,P61916,Q9Y619,P18077,Q7LGA3,O75844,Q8TB37,P50454,Q9Y4P3,O14656,Q14739,Q9NX14,P02545,O60826,P40939,Q9Y375,Q9NPL8 57 +Abnormal erythrocyte enzyme level 0.3272066637916149 0.2933144454278602 0.7692818131298633 1.0 0.9822427396986664 22 P18077,P61313,P62847,P62854,P00813,Q96RL7 6 +Limb tremor 0.4398787961681848 0.2891733609788542 0.7724487162782974 1.0 0.9839196393062716 6 Q9NR77 1 +Dialeptic seizure 0.3025724536745134 0.2890360361959672 0.7725538009772288 1.0 0.9839196393062716 61 P22466,P51812,Q01105,O43292,P00374,Q13510 6 +Abnormality of neuronal migration 0.2717578027296576 0.2888405850478817 0.772703372761286 1.0 0.9839196393062716 172 Q86XL3,O43924,Q10713,Q03252,Q9HC21,Q01105,P56589,Q6NUK1,P37268,Q9UBM7,P23786,O60508,Q969G3,Q15427,Q16134,Q9Y3C6,Q9NZ01,Q9NWS8,Q15392,P40855,P20700,Q2TAA5,O75381,Q9UPT5,O43505,P51812,Q96T60,Q9Y320,Q6ZXV5,O60826,Q96N66 31 +Pes cavus 0.2762866226303941 0.287942314744367 0.7733908954505035 1.0 0.9839196393062716 106 Q8NI60,Q10713,P53007,P13473,P49589,Q99720,Q96RL7,Q8WVX9,O95140,Q8TB36,P04062,O60313,P05023,Q9NR77,Q96T60,Q7LGA3,Q14739,P02545,O15269,P40939 20 +Dyspareunia 0.4652678252450852 0.2873853366407619 0.7738172875417926 1.0 0.9839196393062716 4 O00255,P01889 2 +Increased circulating gonadotropin level 0.3677934574923386 0.2842074896710783 0.7762513761055216 1.0 0.9862088911664436 10 P51659,P16435,P82650 3 +Abnormality of the knee 0.2796733173934134 0.2819334716324482 0.7779945235032519 1.0 0.9870805516947508 97 Q86XL3,Q15041,P16278,P37268,O75477,P23786,P21964,O75431,Q96HY6,P21912,P08236,Q7RTS9,Q969X5,Q13510,Q9NR77,Q9Y619,Q7LGA3,P50454,Q6ZXV5,Q9Y4P3,O14656 21 +Abnormal large intestine morphology 0.2857339975946123 0.2796996168856061 0.7797079722822722 1.0 0.9889857437071254 84 P49748,P51812,O75844,Q8TAA9,Q6PGP7,Q9Y4P3,P21912,P61313,P02545,P53701,P08183 11 +Spastic gait 0.3221553198040031 0.2761287764859192 0.7824491591250258 1.0 0.9908476061716152 23 P20700,Q15041,Q8WVX9,Q9NVI7,O75477 5 +Perseveration 0.4086279416514303 0.2730610528864137 0.7848062846746373 1.0 0.9930245374379084 7 P61916 1 +Meningocele 0.3605496971735636 0.2721498753350705 0.7855067812810643 1.0 0.99345099449705 11 Q10713,Q8TAA9 2 +Abnormal conjugate eye movement 0.2777478622064205 0.2712756727489842 0.7861790155153614 1.0 0.99345099449705 352 O43924,Q9NZJ7,Q10713,Q9NPL8,Q8NI60,P55795,P53007,Q9UHX1,Q9NVI7,P51571,Q9H061,O15118,Q8TAD8,Q53H12,Q6NUK1,Q9H490,P56589,Q9UBM7,P12235,Q5H8A4,Q99720,Q96RL7,Q86YV9,Q8NCH0,Q8N766,Q969G3,P21964,Q96CU9,O43676,Q9Y6M9,P49711,Q8N183,O95202,Q15392,P40855,Q92581,P20700,Q2TAA5,O75381,O96000,P04062,P82930,Q86Y39,P51572,Q92796,P03886,P61313,O75380,Q9BT22,Q9UM00,O75352,O43819,P16435,Q96TA2,P61916,Q9Y619,P07602,P51812,Q96T60,Q7LGA3,Q9P0J0,Q8TB37,Q9Y4P3,O14656,P35637,Q9Y375,Q14739,O60313,P40939,O95470,P38435 71 +Scaling skin 0.3821717386930167 0.2710681831303954 0.7863385919219927 1.0 0.99345099449705 8 O75844 1 +Headache 0.2950124081282269 0.2694094712811923 0.7876145984946528 1.0 0.993763045859828 73 Q969G3,Q9NQZ5,P01889,O00255,P04062,Q8TAA9,P05067,P21912,P03886,O60313,P12235,P23786,P00403 13 +Abnormality of fontanelles 0.3009315927024759 0.2692579185040672 0.7877312128351304 1.0 0.993763045859828 50 Q8NCH0,Q9Y619,Q6NUK1,O75381,P51812,O75844,Q16134,P02545,P56589,Q9BT22,P16435,P40855 12 +Displacement of the urethral meatus 0.2775188861779955 0.2662991836949352 0.7900088017276987 1.0 0.9952650617598772 136 P27635,Q9UHX1,P51571,Q9BUB7,P49589,P56589,P37268,Q9UBM7,Q5H8A4,P48449,Q969G3,P21964,O95202,P40855,P51970,O75381,Q6PGP7,P61313,P16435,Q9Y619,P18077,O75844,Q9UBX3,Q9NX14,P53701,P02545,O60826 27 +Pneumothorax 0.3807000197161633 0.2655952376983204 0.7905509536776385 1.0 0.9952650617598772 8 Q8NCH0,Q9H078 2 +Paranoia 0.4319299146017146 0.2644441765244061 0.7914376747129512 1.0 0.995338681769507 6 P36551,Q96RL7 2 +Spinal deformities 0.4310259627365014 0.2616825185666755 0.7935662191811144 1.0 0.9962325279157136 6 Q8TB36 1 +Decreased number of large peripheral myelinated nerve fibers 0.4417922134540564 0.2611124703117881 0.7940057752681928 1.0 0.9962325279157136 5 Q8TB36,O15269 2 +Axonal degeneration 0.3793666737236424 0.2606656047781789 0.7943503926710163 1.0 0.9962325279157136 8 Q8TB36 1 +Abnormal brain positron emission tomography 0.4415073115860636 0.2602946942688242 0.7946364649511692 1.0 0.9962325279157136 5 Q969G3,Q12824,Q9UQN3,P55072 4 +Abnormal prolactin level 0.4415073115860634 0.2602946942688236 0.7946364649511697 1.0 0.9962325279157136 5 Q9NW13,Q969G3,Q12824,P10644 4 +Increased sensitivity to ionizing radiation 0.44150731158606 0.2602946942688144 0.7946364649511768 1.0 0.9962325279157136 5 Q96MG7,Q969G3,Q12824,P49959 4 +Abnormal size of pituitary gland 0.4415073115860572 0.2602946942688063 0.794636464951183 1.0 0.9962325279157136 5 Q969G3,Q12824,P35222,Q93074 4 +Ulnar deviation of the hand or of fingers of the hand 0.352709900120618 0.2583193209785622 0.7961604761747929 1.0 0.9976578806387836 12 Q14739 1 +Gait imbalance 0.3234384971415887 0.2568772462570267 0.7972735361802517 1.0 0.9981448221406358 21 Q9NR77,Q5H8A4,Q9Y4P3 3 +Coloboma 0.3000840757643772 0.2567080004245133 0.7974041950277515 1.0 0.9981448221406358 54 O43924,Q10713,O43505,Q9UHX1,O95202,Q9UBM7,Q5H8A4 7 +Hypertensive crisis 0.4399120165098084 0.2557348303363951 0.7981555985182656 1.0 0.9983787960603993 5 P21964 1 +Eeg with generalized slow activity 0.4034320096951425 0.2555773470972548 0.7982772119793347 1.0 0.9983787960603993 7 O75503 1 +Abnormality of skin pigmentation 0.2759870183974778 0.2552796115438634 0.7985071460176092 1.0 0.9983787960603993 147 Q13423,Q9NZJ7,Q8IZA0,P07602,P16615,P21964,Q7LGA3,O75844,P04062,Q6PGP7,P03886,P51648,Q14739,P21912,Q06136,P02545,P00403 17 +Thoracic aortic aneurysm 0.294197048230664 0.2549804580992232 0.798738192661343 1.0 0.9983787960603993 38 Q7LGA3,O75844,Q9Y4P3,P49589,P02545 5 +Abnormality of the nasal tip 0.2741325780949431 0.2548044967734603 0.7988741019665135 1.0 0.9983787960603993 110 O43924,P51812,P42892,O75844,Q9UHX1,O43292,P23786,P02545,Q96A33,P16278,P16435 11 +Thin skin 0.3117517015886652 0.2532818926211957 0.8000503876070328 1.0 0.9988205259659748 27 Q13126,O75844,Q6ZXV5 3 +Immunodeficiency 0.2969487054074108 0.2524353072754908 0.8007046123276671 1.0 0.9988205259659748 67 P09601,P21964,Q13432,O95202,P21912,Q9BT22,Q96A33,P00813 8 +Flat face 0.3157819270314098 0.2513989351371691 0.8015056909140996 1.0 0.9989936120870078 24 P50542,O75381,Q9BUB7,Q9Y487,Q96L58,P56589,Q9UM00,P40855,P08236 9 +Abnormal circulating protein concentration 0.2732556093870358 0.2505160984655212 0.8021882567552661 1.0 0.999484547481006 160 Q5JTV8,Q86VD7,P13473,P23786,P12235,Q96RL7,Q8N511,P50402,Q9NWM8,P09493,Q5XKP0,Q9BTV4,O43772,Q6PGP7,Q969X5,P10253,Q9BT22,Q9UJS0,P42167,P49748,O43505,Q9HC07,Q6ZXV5,Q9Y4P3,P02545,P40939,O95470 27 +Lack of skin elasticity 0.3356492840418702 0.2499658880882943 0.8026137287239512 1.0 0.999484547481006 16 O75844 1 +Oligodactyly 0.4268684747786258 0.2491174356296987 0.8032699428529844 1.0 0.999484547481006 6 Q9UBC2 1 +Abnormal electrophysiology of sinoatrial node origin 0.3454070485432762 0.2477492227882378 0.8043284445423589 1.0 0.999484547481006 13 P21912 1 +Hypocalcemia 0.3351212862987688 0.2472368401703666 0.8047249357568786 1.0 0.999484547481006 16 P40939,P21964 2 +Congenital contracture 0.2990089117977409 0.2468594081534879 0.8050170318162704 1.0 0.999484547481006 53 Q8NCH0,P02545,O75844,P04062,O14656,Q969X5,Q15392,Q96A33,Q92581 9 +Dysplasia of the femoral head 0.4462852535772821 0.2467861799413161 0.8050737065591829 1.0 0.999484547481006 3 O75431 1 +Abnormal femoral head morphology 0.3229975951861079 0.2443206997910311 0.8069824530500378 1.0 1.0 20 Q7RTS9,Q7LGA3,P16278 3 +Impairment in personality functioning 0.2781600924170905 0.2430911277536264 0.8079348041341627 1.0 1.0 219 Q9NZJ7,P55795,P01889,Q8TAA9,P35670,O76024,P49589,P12235,Q96RL7,P21964,O75503,O43681,O96008,Q8N183,Q15165,P50897,P21912,Q9NZ01,Q92581,P20700,P16615,P04062,Q6DKK2,P03886,Q9UM00,P00403,P07602,P51812,Q7LGA3,Q9P0J0,Q9Y4P3,O14656,P35637,P17900,Q96N66 35 +Abnormal chorioretinal morphology 0.2967394584595524 0.2418407153610705 0.8089035888487239 1.0 1.0 33 Q10713,Q9Y619,O43505,O75381,P53701,Q9NX14,O60826,P56589,Q5XKP0,P40939,P40855 11 +Hepatosplenomegaly 0.2945376460343786 0.2405332439831355 0.8099168946197404 1.0 1.0 41 Q13510,P10619,P04062,Q14739 4 +Small for gestational age 0.278012174803288 0.2374835799013582 0.8122816562325936 1.0 1.0 91 Q9UHX1,Q9BUB7,P49589,Q6NUK1,Q969M3,Q8IY17,P49711,O95202,Q6PGP7,Q92796,Q9Y2Z2,P61313,P16435,P49748,Q9Y619,P51812,P18077,P22695,P62847,P40939 20 +Delayed cns myelination 0.2895464699221642 0.2364208667203564 0.8131061057784401 1.0 1.0 35 Q8WVX9,Q7LGA3,P49589,Q9H490,O60508 5 +Inferior lens subluxation 0.441259134345143 0.2343520552255676 0.8147116766413642 1.0 1.0 3 P29992,O75533 2 +Metamorphopsia 0.441259134345143 0.2343520552255676 0.8147116766413642 1.0 1.0 3 P29992,O75533 2 +Choroidal melanoma 0.441259134345143 0.2343520552255676 0.8147116766413642 1.0 1.0 3 P29992,O75533 2 +Lens subluxation 0.441259134345143 0.2343520552255676 0.8147116766413642 1.0 1.0 3 P29992,O75533 2 +Uveal melanoma 0.441259134345143 0.2343520552255676 0.8147116766413642 1.0 1.0 3 P29992,O75533 2 +Ocular pain 0.441259134345143 0.2343520552255676 0.8147116766413642 1.0 1.0 3 P29992,O75533 2 +Photopsia 0.441259134345143 0.2343520552255676 0.8147116766413642 1.0 1.0 3 P29992,O75533 2 +Mydriasis 0.441259134345143 0.2343520552255676 0.8147116766413642 1.0 1.0 3 P29992,O75533 2 +Keratoconjunctivitis 0.3580656537530546 0.2299590054299123 0.8181236249908004 1.0 1.0 9 Q14739 1 +Epileptic spasm 0.294241253494486 0.2285244118015425 0.8192385802846729 1.0 1.0 68 Q01105,Q9UBX3,P03886,Q13510,Q96N66 5 +Abnormal ciliary body morphology 0.4413831880798459 0.2241167839458746 0.8226664329374318 1.0 1.0 4 P11047,P29992,O75533 3 +Abnormal visual field test 0.4413831880798346 0.2241167839458464 0.8226664329374538 1.0 1.0 4 Q969G3,Q12824,P35222 3 +Reduced circulating prolactin concentration 0.4413831880798328 0.2241167839458418 0.8226664329374573 1.0 1.0 4 Q9NW13,Q969G3,Q12824 3 +Abnormality of the musculature of the limbs 0.2683844604895311 0.2233381498199883 0.8232723377493327 1.0 1.0 171 Q9NZJ7,P53007,Q9HC21,P35670,P12235,Q99720,Q96RL7,Q8N766,P50402,Q969G3,Q8WVX9,O95140,Q8TB36,P21912,Q9BTV4,Q2TAA5,Q7RTS9,Q969X5,P61313,Q13510,O43819,O60313,P05023,Q9NR77,P07602,P18077,Q96T60,O14979,Q13126,Q14739,P02545,O15269,P40939 33 +Progressive leukoencephalopathy 0.4362001124227139 0.222184951136573 0.8241699086045757 1.0 1.0 3 Q9Y263,Q5JTZ9 2 +Abnormality of the autonomic nervous system 0.294473576677457 0.2216608647815484 0.8245778976066516 1.0 1.0 66 P41440,Q9NZJ7,Q10713,P21964,P20700,P07602,P42892,O43681,P04062,O76024,O15269,Q9UBM7,Q96RL7 13 +Convex nasal ridge 0.309902418131846 0.2203637600057881 0.8255878670181953 1.0 1.0 25 O75844,O95202,P02545 3 +Distal muscle weakness 0.2927957851733896 0.2183413900606035 0.8271631277033213 1.0 1.0 69 P41440,Q9NR77,P53007,Q96T60,O95140,P35637,Q8TB36,P02545,O15269,P40939,Q99720,Q96RL7 12 +Axial muscle weakness 0.4160909650467944 0.2176199302876976 0.8277252545130034 1.0 1.0 6 Q8TD16,P02545 2 +Restrictive behavior 0.425759280089991 0.2167493587268391 0.828403679553432 1.0 1.0 5 Q9UQN3,Q01082,P51608,P55072 4 +Acute coronary syndrome 0.3191323718347065 0.2146902003970539 0.8300088633881597 1.0 1.0 19 P02545,O75844,Q9Y4P3 3 +Tricuspid valve prolapse 0.4327190289979863 0.2140187044032461 0.8305324711006739 1.0 1.0 3 P53701 1 +Deep plantar creases 0.4147052038641065 0.2136859076216877 0.8307920016129346 1.0 1.0 6 P21281,Q9Y487,O00170 3 +Abnormality of adrenal physiology 0.2885874947718919 0.2136568998025858 0.8308146241433516 1.0 1.0 37 Q13423,P50542,Q969G3,P51809,O75381,P51659,P82663,O00255,P33991,O00170,O95470,P56589,Q9Y2R9,P16435,P40855 15 +Hyperinsulinemic hypoglycemia 0.3900504015405154 0.2123573327469659 0.8318282701509117 1.0 1.0 7 Q16836,O00255,P40939 3 +Nail dysplasia 0.2898714651044571 0.2118748847225188 0.8322046448585145 1.0 1.0 34 P42892,P10321,P16615,P51812 4 +Jaundice 0.2954157610908014 0.2116212073503522 0.8324025629565075 1.0 1.0 58 P61916,P49748,O75381,P28288,Q16134,P35670,P49711,O15118,Q6PGP7,Q14739,P00374,P56589,Q9UJS0 13 +Short proximal phalanx of finger 0.376791233492558 0.2090493143373485 0.834409741711595 1.0 1.0 2 P42345 1 +Acromesomelia 0.3767912334925469 0.2090493143373218 0.8344097417116159 1.0 1.0 2 P63000 1 +Abnormal circulating androgen level 0.3363487181872724 0.206911637494239 0.8360788677815223 1.0 1.0 13 P16435 1 +Increased blood pressure 0.2797904515892732 0.2067243410041503 0.8362251466232957 1.0 1.0 84 Q10713,P21964,P42892,O75844,P04062,Q8TAA9,Q9Y4P3,Q9BUB7,P03886,P21912,P02545,P16435,P00403 13 +Short upper lip 0.4119624902319858 0.2059794665658338 0.8368069506901299 1.0 1.0 6 O95202 1 +Neuroendocrine neoplasm 0.3360408076310496 0.2055520837449087 0.8371408097777691 1.0 1.0 13 O00255,P21912,P02545 3 +Abnormal platelet morphology 0.4195887350362113 0.2006056483284386 0.8410069411293482 1.0 1.0 5 P12814 1 +Large hands 0.3297784854219862 0.1993242291112885 0.8420091273360408 1.0 1.0 14 P51812 1 +Polycythemia 0.3725765664512508 0.1989766327610896 0.842281023457998 1.0 1.0 2 P00387 1 +Bone spicule pigmentation of the retina 0.3495583633969847 0.1981572201714558 0.8429220570991165 1.0 1.0 9 Q9UG56 1 +Abnormal lactate dehydrogenase level 0.3161377420269435 0.1978276912247329 0.84317987985014 1.0 1.0 19 O43505,P23786,P10253,Q9UJS0,Q96RL7 5 +Elevated calcitonin 0.3455373817099981 0.1948837181620583 0.8454839808294294 1.0 1.0 10 O00255,P21912 2 +Macrodontia of permanent maxillary central incisor 0.4230271880585621 0.1921814356231779 0.8476000870806395 1.0 1.0 3 P49711 1 +Abnormality of the nasolabial region 0.3831852710924376 0.1912494233053788 0.8483301839628297 1.0 1.0 7 Q8NCH0,P36543,O14656 3 +Prominent nasolabial fold 0.3831852710924376 0.1912494233053788 0.8483301839628297 1.0 1.0 7 Q8NCH0,P36543,O14656 3 +Muscular dystrophy 0.3025834887832588 0.1896595710259499 0.84957590336239 1.0 1.0 27 Q5JTV8,P50402,O43505,P22626,Q96T60,P02545,Q9BTV4 7 +Anonychia 0.3177890620928432 0.1880351740230356 0.8508490780662428 1.0 1.0 18 Q6NUK1,Q14739,P16615 3 +Progressive pes cavus 0.4209203871808167 0.187611578017265 0.8511811494689832 1.0 1.0 3 Q12768 1 +Secondary microcephaly 0.2789939762691648 0.1842306543111283 0.8538325123826251 1.0 1.0 83 Q9HC21,Q9HC07,Q9UHX1,Q86Y39,P50897,P00374,Q5XKP0 7 +Abnormal upper limb bone morphology 0.2686233691201473 0.1841367498598411 0.8539061771491387 1.0 1.0 108 O43924,Q6NUK1,P51812,Q7LGA3,O75844,Q9UHX1,Q9Y4P3,Q7RTS9,Q14739,O00116,P02545,O95202,Q9UBM7,P16278,P16435 15 +Shortening of all distal phalanges of the fingers 0.3310949349150353 0.1839838810294655 0.8540261001386182 1.0 1.0 13 P51812 1 +Leukopenia 0.2924314507672492 0.1826529918764368 0.85507030218989 1.0 1.0 54 Q14108,P04062 2 +Ventricular fibrillation 0.4235468000574274 0.1817504335271396 0.8557785848302382 1.0 1.0 4 P49748,Q9NX14 2 +Acne 0.3194618960917127 0.1812585174473927 0.8561646649193226 1.0 1.0 17 Q92542,P21964,P01889,Q9NZ08,Q9H488,Q9Y4L1 6 +Increased urinary cortisol level 0.4179314221472812 0.1812378353211536 0.8561808980305166 1.0 1.0 3 P10644,P04150 2 +Abnormal urine hormone level 0.4179314221472812 0.1812378353211536 0.8561808980305166 1.0 1.0 3 P10644,P04150 2 +Flat occiput 0.3217437868539707 0.1800287700952479 0.8571299819203702 1.0 1.0 16 P56589,Q9BUB7,P40855,O75381 4 +Abnormal tongue physiology 0.3128867867670539 0.1797601517947667 0.8573408682045196 1.0 1.0 19 Q13510,Q9NWS8 2 +Abnormal meningeal morphology 0.3047053804025754 0.1795311352228124 0.8575206720904236 1.0 1.0 24 Q9UHX1,Q10713,Q8TAA9 3 +Abnormality of pancreas physiology 0.2905181650942669 0.1793807204004368 0.8576387687444518 1.0 1.0 47 P09601,Q9UHX1,Q14739,P03886,P00403 5 +Widely spaced incisors 0.411136107986509 0.1793665149124916 0.8576499222022353 1.0 1.0 5 Q8WXI9,Q8WVM7,Q9BSJ2,Q99496 4 +Scaphocephaly 0.4021317641032398 0.1792475312676573 0.8577433434851571 1.0 1.0 6 Q969X5,P40855 2 +Supraventricular tachycardia 0.4207860314825546 0.1755847812351874 0.860620159407371 1.0 1.0 4 P02545 1 +Abnormal circulating bilirubin concentration 0.3004430752283308 0.1751162628244817 0.8609882798350414 1.0 1.0 27 P14314,P41440,P28288,P23786,Q14739,Q9UJS0,P40855 7 +Tongue atrophy 0.4202980039358974 0.1745059972057267 0.8614678179929507 1.0 1.0 4 O00567,Q9NQT5,P07196 3 +Partial albinism 0.3616184321438594 0.1743494403631981 0.8615908464008093 1.0 1.0 2 Q9Y2Q5 1 +Exodeviation 0.3002642293360374 0.173906744528531 0.8619387520339663 1.0 1.0 27 P55795,Q9UHX1,P82930,O43819,P40939 5 +Hemiparesis 0.3149839544446099 0.1731737602303582 0.8625148483121676 1.0 1.0 18 P01889,O60313,P03886,P00403 4 +Bulbar palsy 0.3326001235375814 0.1726546801015115 0.8629228687373149 1.0 1.0 12 P35637,O14908,O43681,P53007 4 +Abnormality of the odontoid process 0.3538628947673623 0.1720192874732028 0.8634223658077897 1.0 1.0 8 Q7RTS9,P16278 2 +Rectal prolapse 0.3357060860382574 0.1702570467571251 0.864807989723783 1.0 1.0 11 P51812 1 +Delayed closure of the anterior fontanelle 0.3277209084151667 0.1695697479133278 0.8653485156174623 1.0 1.0 13 P51812,P36543,P40855,O75381 4 +Diffuse mesangial sclerosis 0.3141764274177966 0.1689307181353891 0.8658511368473143 1.0 1.0 18 O95470 1 +Myoclonic spasms 0.3979321449007112 0.1682625846318627 0.8663767072862105 1.0 1.0 6 Q10713 1 +Hypoplastic nipples 0.3315005511645112 0.1682056047624512 0.8664215318070185 1.0 1.0 12 Q6NUK1,Q96A33 2 +Abnormality of endocrine pancreas physiology 0.3752191795928109 0.1677104425841281 0.8668110805618929 1.0 1.0 7 O00255,Q14739 2 +Hemoglobinuria 0.4163621028957027 0.1659286114588866 0.8682131309092 1.0 1.0 4 Q969N2,P11413,Q9H0P0 3 +Skin tags 0.3093249985132206 0.1654120641622639 0.8686196586468189 1.0 1.0 20 Q9UHX1,O95202,O60826 3 +Aplasia hypoplasia of the proximal phalanges of the hand 0.4159112344450835 0.1649600578195699 0.8689754205279909 1.0 1.0 4 O75962 1 +Bilateral cleft lip and palate 0.3568418094970456 0.1643252930605266 0.8694750713496573 1.0 1.0 2 O60716 1 +Curly hair 0.3302142696372315 0.163034030587491 0.8704916405867189 1.0 1.0 12 Q96A33,Q6PGP7 2 +Congenital malformation of the left heart 0.4137058364483936 0.1602641069173064 0.8726730318976204 1.0 1.0 4 O60826 1 +Upper motor neuron dysfunction 0.2597050293382726 0.1593749763053048 0.8733734529216772 1.0 1.0 405 Q86XL3,Q9NZJ7,Q8NI60,Q10713,Q15041,P01889,Q9NVI7,O15118,Q01105,P49589,P16278,P56589,Q9H490,O75477,Q99720,O60508,Q5BJH7,Q969G3,Q96CU9,Q8WVX9,O75503,O43681,O95140,Q8N183,Q15165,P50897,P21912,Q9NZ01,Q15392,Q9Y3C6,Q5XKP0,O15121,P40855,P51970,Q8N2K0,P20700,Q2TAA5,O75381,P11117,P22626,P04062,Q6DKK2,P82930,P51572,Q7RTS9,Q92796,P03886,P51648,O43292,Q13510,O43819,P00403,O60313,Q13423,Q9NR77,P61916,P41440,P07602,O43505,P51812,Q96T60,Q2M389,Q9P0J0,Q8TB37,Q9H078,Q9Y320,Q6ZXV5,Q9Y4P3,P35637,Q9UBX3,P17900,O14773,Q96N66,P40939,Q9Y287 75 +Abnormal caudate nucleus morphology 0.3359511037177679 0.1592416631235312 0.8734784802080473 1.0 1.0 10 O43819,P37198,Q96RL7 3 +Abnormality of facial soft tissue 0.2699239637313589 0.1588971550812309 0.8737499021358026 1.0 1.0 125 Q03252,P53007,Q86VD7,Q9UHX1,P56589,Q9UBM7,P12235,Q969G3,P21912,P40855,O75381,O00255,P04062,Q92796,P10253,Q13510,O43819,P16435,O60313,P51812,O75844,Q9Y4P3,O60826,P02545 24 +Carcinoid tumor 0.412943311496482 0.1586565975618738 0.8739394350735623 1.0 1.0 4 P02545 1 +Small earlobe 0.3717637572034042 0.1578285114981628 0.8745919313007748 1.0 1.0 7 P21964,P10586 2 +Muscle fibrillation 0.3169542900479657 0.1569396827187647 0.8752923850625249 1.0 1.0 16 Q13510 1 +Proportionate tall stature 0.4051718630265243 0.155488660395248 0.8764360929151593 1.0 1.0 3 O00255 1 +Abnormal choroid morphology 0.2796907083589474 0.1551067462906919 0.8767371637832602 1.0 1.0 35 Q10713,Q9Y619,O43505,O75381,P53701,Q9NX14,O60826,P56589,Q5XKP0,P40939,P40855 11 +Easy fatigability 0.2997600236066485 0.1542592834523336 0.8774053000803945 1.0 1.0 25 P53007,Q9NWM8,Q53H12,P21912,P12235 5 +Abnormal peripheral action potential amplitude 0.3369515950628562 0.1535259071403912 0.8779835615385758 1.0 1.0 9 Q96RL7 1 +Long fingers 0.2751992989542811 0.1509812765063503 0.8799904857584631 1.0 1.0 84 Q8NCH0,P21964,P51812,P42892,Q9UHX1,Q06136,P23786,Q5H8A4,P16435 9 +Arrhinencephaly 0.3301294402944258 0.1490563641649342 0.8815091575067104 1.0 1.0 11 P21964,Q8TAA9 2 +Dysuria 0.3465416524594478 0.1487114639222629 0.8817813149286795 1.0 1.0 8 O76024 1 +Woolly hair 0.3886057548543269 0.1448266108978143 0.8848477712692939 1.0 1.0 6 Q96A33 1 +Gastrointestinal hemorrhage 0.2782730215778294 0.1436567284433699 0.8857715423735981 1.0 1.0 35 P14314,P21964,P49257,P01889,O00255,Q9UHX1,O76024,P21912,Q14739,Q9UJS0 10 +Decreased head circumference 0.2717467793326075 0.1434885846510397 0.8859043260900439 1.0 1.0 502 Q03252,P53007,P49589,P56589,Q06136,Q99720,Q8N766,Q969G3,Q96CU9,Q15427,O43676,Q8WVX9,P82663,P50897,Q15392,O43772,P04062,Q86Y39,P03886,P51648,Q16740,P07602,P51812,Q9HC07,Q15800,Q96N66,O95470,Q86XL3,Q9NZJ7,Q9HC21,Q9UHX1,Q01105,Q5H8A4,P48449,Q5BJH7,Q9UG56,Q9Y6M9,P21912,P00374,Q5XKP0,Q96A33,P61313,Q9BT22,Q9UM00,P16435,P46977,Q6ZXV5,Q9Y3A4,Q10713,Q9BUB7,Q9UBM7,P23786,P21964,Q9NZ01,O95202,O15121,P51970,Q2TAA5,O96000,Q7RTS9,P49748,O43505,Q7LGA3,Q9H078,Q9Y320,Q9Y4P3,P53701,Q9Y375,Q9NPL8,P55795,P51571,Q6NUK1,Q8N183,Q92581,P20700,O75381,P82930,P51572,O75380,Q96T60,P22695,Q8TB37,O14656,P35637 84 +Hypoventilation 0.3157165349691956 0.1427410899627837 0.8864946638782472 1.0 1.0 15 Q8N183,Q13724,O75380,O43819,O75306 5 +Abnormal metatarsal morphology 0.2922794321978681 0.1410426354860174 0.8878362607307695 1.0 1.0 29 Q7RTS9,O95202,Q15392,Q9UBM7,P16435 5 +Aplasia hypoplasia of the phalanges of the hand 0.2879380102907675 0.140855113295111 0.8879844029189092 1.0 1.0 61 P51798,Q969G3,P51812,Q8IWS0,O75962,Q9UHX1,O75844,Q7RTS9,Q96S52,Q92796,Q14739,O60826,P02545,Q6NUK1,Q5JRA6,P38435,Q6UX04,P16435 18 +Skin pit 0.3165802380983231 0.1407692308655901 0.8880522511880233 1.0 1.0 14 O95202,P16615 2 +Cerebral hypoplasia 0.3113079914978589 0.1405798668566165 0.8882018541878562 1.0 1.0 17 Q86XL3 1 +Puberty and gonadal disorders 0.2629615971879274 0.1403664952938247 0.8883704286156786 1.0 1.0 173 Q14108,Q9NVI7,O76024,P49589,Q9UBM7,P48449,O95202,P04062,P03886,Q16740,Q9BT22,P16435,P00403,Q13423,Q7LGA3,O75844,Q9Y4P3,Q15800,P02545,O95470 20 +Cutaneous finger syndactyly 0.396375978969387 0.1391275354083123 0.8893493697135333 1.0 1.0 3 Q9Y619 1 +Visual impairment 0.2763065809106124 0.138611697297867 0.889756999439568 1.0 1.0 318 Q9NZJ7,Q10713,P53007,Q13432,P13473,P01889,Q9UHX1,P30533,Q9H061,Q01105,Q96S66,P16278,P56589,Q9H490,P37268,P12235,Q6P4A7,P48449,Q5BJH7,Q86YV9,Q8N766,Q969G3,Q96CU9,O43676,Q9Y6M9,O75503,O43681,O95140,Q8N183,Q9Y6B6,P50897,P21912,Q9NZ01,Q6P4Q7,Q5XKP0,Q96A33,P40855,P20700,O75381,O96000,O00255,Q86Y39,P03886,O43292,O75380,O43819,Q96TA2,Q6UX04,P00403,O60313,P07602,O43505,Q7LGA3,Q8NHS3,Q8TB37,Q9Y4P3,Q8WWV3,P53701,P17900,O14773,Q96N66,P40939,Q9Y375,Q9NPL8,Q9Y287 65 +Motor delay 0.2766009379882176 0.1381814702193061 0.8900969992267131 1.0 1.0 253 Q10713,Q03252,P53007,Q86VD7,Q01105,P49589,Q53H12,Q99720,Q5H8A4,P48449,Q5BJH7,Q8NCH0,O60508,Q8WVX9,Q9NWM8,P82663,O95140,Q8TB36,Q9Y3C6,P21912,Q9NZ01,Q5XKP0,P51970,P20700,P04062,Q7RTS9,Q92796,P03886,P10253,Q13510,O43819,Q9UM00,Q6UX04,P16435,P00403,O60313,Q9NR77,P51812,Q96T60,Q7LGA3,Q9H078,Q6ZXV5,P35637,P02545,Q96N66,P40939 46 +Multifactorial inheritance 0.3196131556828794 0.1359752524509732 0.8918408449185542 1.0 1.0 13 P42892,P01889,P10321 3 +Developmental stagnation 0.3422065855851523 0.1353937222111247 0.892300587380451 1.0 1.0 8 Q9H270,P16278 2 +Abnormal cranial nerve morphology 0.2836080737122547 0.1308484947295969 0.8958951595045674 1.0 1.0 71 Q969G3,P53007,O75381,P22626,O00255,Q13510,Q9UHX1,P51812,Q92796,P21912,Q02978,P56589,O43819,P12235,P40855,Q96TA2 16 +Gastroparesis 0.3406381547490852 0.1306658866677341 0.8960396194163736 1.0 1.0 8 Q9BUB7 1 +Thin eyebrow 0.3113415290439409 0.1305927081060887 0.896097511412846 1.0 1.0 16 P48449 1 +Spotty hyperpigmentation 0.3385782523180685 0.1299801222867118 0.8965821533783491 1.0 1.0 2 O75531 1 +Impaired vibration sensation in the lower limbs 0.3180955973892999 0.12985684188438 0.8966796902712644 1.0 1.0 13 Q9NR77,Q8WVX9,Q9H0B6,Q12768,O43819 5 +Childhood onset 0.2784303189372711 0.1292465337966394 0.8971625763208912 1.0 1.0 37 P50402,Q9NR77,O75431,Q8TB36,P22830 5 +Abnormality of the maxilla 0.2783868112563142 0.1288920803032563 0.8974430433983707 1.0 1.0 37 Q9UM00,Q14739,Q12959,P51812 4 +Macrocephaly at birth 0.3374543411070534 0.1280713892274372 0.898092477650392 1.0 1.0 2 P50570 1 +Generalized hypotonia 0.2636431536650359 0.1278768740462496 0.8982464126093868 1.0 1.0 387 O43924,Q8TAD8,Q53H12,P56589,O14949,Q8N766,Q8N511,Q96CU9,O43676,P12694,P49711,Q70HW3,P50897,P40855,O75880,O43772,Q86Y39,O75352,O43819,Q96TA2,Q2M389,Q9NR77,Q9Y619,P07602,P51812,Q9HC07,P50454,Q8TCJ2,Q9UBX3,Q13724,P98175,Q96N66,P40939,O95470,Q9NZJ7,Q99797,Q86VD7,Q9UHX1,O15118,Q01105,P13073,Q5H8A4,Q5BJH7,Q8NCH0,Q9Y6M9,P21912,P00374,Q5XKP0,Q96A33,O43292,Q9BT22,P46977,Q9P0J0,P17900,Q92643,Q10713,Q9NVI7,Q9BUB7,Q9UBM7,P23786,Q6P4A7,Q9NZ01,O95202,Q9BWD1,Q8NI60,P51571,Q6NUK1,P12235,O14678,O43681,O75431,Q8N183,Q9NWS8,Q92581,O75381,P11117,P82930,P10253,P61916,O14656,O60826 81 +Chronic axonal neuropathy 0.3972448692718495 0.1274216070550305 0.8986067156710642 1.0 1.0 4 O15269,Q96MW5,P04792 3 +Genu varum 0.3210175436554913 0.1271255102101554 0.8988410610355437 1.0 1.0 12 Q7RTS9,Q96HY6 2 +Severe global developmental delay 0.2778200709505432 0.126728240218098 0.8991554935759898 1.0 1.0 79 P51812,Q9HC21,Q7LGA3,Q92581,O15121,Q7RTS9,P03886,Q9H490,Q9BT22,Q96A33,Q5H8A4,P51970 12 +Constitutional symptom 0.2760738701718759 0.1266022385248558 0.8992552251134542 1.0 1.0 254 Q9NZJ7,Q14108,Q03252,P01889,Q8TAA9,P35670,Q53H12,O75477,Q01844,Q99720,P23786,P12235,P50402,Q969G3,P21964,Q8WVX9,O43681,O95140,Q70HW3,Q96HY6,Q15165,P21912,Q9BTV4,Q92581,P20700,P22626,O00255,P04062,Q92796,Q02978,Q13510,Q9UJS0,O60313,Q13423,Q9NR77,P49748,P07602,P51812,P42892,O75844,Q9Y4P3,P40939,P35637,Q15800,Q14739,P02545,O15269,P14314,P07196,Q8WWI5 50 +Amyloidosis 0.3874827826052869 0.1255330419111989 0.9001015682639499 1.0 1.0 5 Q9Y287 1 +Abnormal blood gas level 0.3884204609331171 0.1253102655682973 0.9002779254970172 1.0 1.0 3 P06753,Q9Y3E5 2 +Abnormal vitamin b12 level 0.3596016962782051 0.124683329917399 0.9007742552035148 1.0 1.0 7 O14678 1 +Neoplasm of the peripheral nervous system 0.3055159527950272 0.124464620315412 0.9009474114142496 1.0 1.0 18 Q969G3,P21912,O00255,P02545 4 +Chromosomal breakage induced by ionizing radiation 0.3949957829631698 0.1232391196744469 0.901917748642316 1.0 1.0 4 Q969G3,Q12824,Q99496 3 +Spasticity 0.2744217827507464 0.122311051831575 0.9026526796206866 1.0 1.0 329 Q86XL3,Q9NZJ7,Q10713,Q15041,Q9NVI7,O15118,Q01105,P16278,P56589,Q9H490,O75477,Q99720,O60508,Q5BJH7,Q96CU9,Q8WVX9,O75503,O43681,O95140,Q8N183,Q15165,P50897,P21912,Q9NZ01,Q15392,Q9Y3C6,Q5XKP0,O15121,P40855,P51970,P20700,Q2TAA5,O75381,P11117,P04062,Q6DKK2,P82930,Q7RTS9,P03886,P51648,O43292,Q13510,P61916,P07602,O43505,P51812,Q96T60,Q9P0J0,Q8TB37,Q9H078,Q9Y320,Q6ZXV5,Q9Y4P3,P35637,Q9UBX3,P17900,O60313,Q96N66,Q9Y287 59 +Abnormality of hindbrain morphology 0.276678172009535 0.1222381385652343 0.9027104227119972 1.0 1.0 300 O43924,Q14108,Q10713,Q8NI60,P55795,P53007,Q9HC21,Q9NVI7,Q8TAA9,P49589,P13073,Q6NUK1,Q9H490,O75477,P23786,Q99720,Q5H8A4,Q9UBM7,Q8N766,Q5BJH7,Q969G3,Q96CU9,P12235,O60508,Q8WVX9,O75503,Q9Y3C6,P21912,O95202,P00374,Q5XKP0,O15121,P51970,Q92581,Q8N2K0,P20700,Q6DKK2,Q9UPT5,P51572,O43292,Q9BT22,Q9UM00,Q96TA2,P16435,O60313,P41440,O43505,P51812,P46977,Q96T60,Q8NHS3,Q8TB37,Q9H078,Q9Y320,Q9Y4P3,P35637,O60826,O14773,Q92643,Q8IV08 60 +Abnormality of the uterus 0.2862210812386063 0.1215873200421836 0.903225856117122 1.0 1.0 57 P21964,P51812,P21912,O95202,Q16740,Q9UBM7 6 +Zonular cataract 0.3195481259975744 0.1215669770855198 0.9032419679326718 1.0 1.0 12 O76024,P08670,Q8WWV3 3 +Abnormal male reproductive system physiology 0.2807471067873275 0.1212123962479888 0.9035228057293598 1.0 1.0 41 Q13423,Q969G3,P20700,P04062,Q9Y4P3,O76024,P16435 7 +Metaphyseal widening 0.3012856806493053 0.1212008209922138 0.903531973854626 1.0 1.0 20 Q7RTS9,Q14739,P16278 3 +Abnormal emotion affect behavior 0.2743146319637501 0.1183407936743934 0.9057976357975 1.0 1.0 240 Q9NZJ7,Q10713,Q9HC21,Q9UHX1,P35670,Q01105,P49589,P37268,Q9UBM7,Q5BJH7,O75503,Q15165,P50897,P21912,O43772,P04062,Q13510,Q9UM00,P54802,P07602,P51812,Q9P0J0,P17900 23 +Abnormality of ocular smooth pursuit 0.2965369254265192 0.1168238862113997 0.9069996148971384 1.0 1.0 23 O14773,P46977 2 +Decreased circulating copper concentration 0.3825182686902821 0.1156599394388183 0.9079220568034498 1.0 1.0 3 Q15904,P61966 2 +Lymphoproliferative disorder 0.382508337600883 0.1152935631570467 0.9082124401978042 1.0 1.0 5 Q9H0U3 1 +Shawl scrotum 0.3752989716997716 0.1137441958084615 0.9094405766576116 1.0 1.0 6 Q9UM00 1 +Retinal atrophy 0.2860467304967655 0.1099597754766451 0.9124412759263884 1.0 1.0 30 Q10713,P51648,P04062 3 +Hyperpituitarism 0.2991819918277011 0.1099273839619797 0.9124669648868966 1.0 1.0 20 Q969G3,P51659,O00255,P33991,P82650,O00170,P16435 7 +Abnormal eyelid physiology 0.3216966197477286 0.1097742007778165 0.91258845216319 1.0 1.0 10 Q9NQZ5,Q96RL7 2 +Facial diplegia 0.3187750776454495 0.1079952192716086 0.9139994844996766 1.0 1.0 11 O43819,P12235 2 +Telangiectasia of the skin 0.2922779423575992 0.1073487513903541 0.9145123099415132 1.0 1.0 25 Q8IZA0,Q14739 2 +Aplasia hypoplasia involving the metacarpal bones 0.2917002819243068 0.1037986440023013 0.917329142587222 1.0 1.0 25 Q14739,P16435,P51812 3 +Abnormality of chorioretinal pigmentation 0.37649236470248 0.1034218930533267 0.9176281371695671 1.0 1.0 5 Q5XKP0 1 +Abnormality of corneal size 0.2798657136724389 0.1022405114950457 0.9185657726936638 1.0 1.0 43 Q8NCH0,O43505,Q9NWM8,O95202,Q5H8A4 5 +Cranial asymmetry 0.369860641876058 0.1018577722172552 0.9188695684581172 1.0 1.0 6 O95202 1 +Abnormality of fibula morphology 0.316486068241169 0.1000738653536718 0.9202856835819552 1.0 1.0 11 Q96HY6,O75431,P16435 3 +Peripheral visual field loss 0.3721191680719579 0.0998924316479724 0.9204297249678212 1.0 1.0 3 P31040,Q6UX04 2 +Periorbital fullness 0.2962880969335255 0.0993784866816041 0.9208377633379836 1.0 1.0 21 P62266,P51812,Q7LGA3,Q92796,P40855 5 +Lissencephaly 0.2835156772522647 0.0985847263068979 0.9214679975798492 1.0 1.0 62 Q86XL3,P20700,O43505,Q9HC21,Q16134,Q9Y320,Q6ZXV5,Q9NWS8,Q15392,P23786 10 +Focal t2 hyperintense basal ganglia lesion 0.2959722331111638 0.0976636466991533 0.922199383242624 1.0 1.0 21 Q96CU9,Q9P0J0,Q8N183,P03886,O75251,Q16795,O75306,O00483 8 +Abnormality of the urethra 0.2660387225636823 0.0975592842751602 0.92228225665861 1.0 1.0 147 P01889,Q9UHX1,Q9BUB7,P49589,P37268,Q9UBM7,Q5H8A4,P48449,P21964,O95202,P51970,Q6PGP7,P61313,P16435,O75844,Q9Y4P3,Q9UBX3,P53701,P02545 19 +Abnormal facial expression 0.2753717990352382 0.0974287371122547 0.9223859243666268 1.0 1.0 34 P04062 1 +Aplasia hypoplasia of the ribs 0.2884050813447614 0.0958153881798507 0.9236671955911872 1.0 1.0 27 Q15427,Q9UHX1,Q8TAA9,O14656,Q96HY6,Q14739,O60826 7 +Abnormal csf pyruvate family amino acid concentration 0.3723284589426356 0.0955344392053192 0.9238903368162124 1.0 1.0 5 P36776,O00330,O00483,P08559 4 +Abnormality of lens shape 0.3152570946895259 0.0950983037948786 0.924236745347114 1.0 1.0 2 P11047 1 +Difficulty climbing stairs 0.3046168746192019 0.0944875855648886 0.9247218436086548 1.0 1.0 15 P40939,P12235 2 +Chronic sinusitis 0.3714907604911988 0.0939802547534085 0.9251248417298188 1.0 1.0 5 Q03519 1 +Abnormality of urine calcium concentration 0.3051779235117106 0.0935609879955217 0.9254579006948234 1.0 1.0 14 Q9Y4P3,P35670 2 +Overriding aorta 0.327653247725536 0.0934240828964168 0.9255666588000512 1.0 1.0 8 P53701,Q9Y4P3 2 +Keratitis 0.3113099747389372 0.0913565432351372 0.9272092907725896 1.0 1.0 12 Q14739 1 +Pollakisuria 0.3752502746843311 0.089681284046984 0.9285404891697328 1.0 1.0 4 Q8WVX9 1 +Nuclear cataract 0.3631966156083607 0.0879486156915646 0.9299175165420828 1.0 1.0 6 O76024 1 +Abnormal serum iron concentration 0.3729556917656815 0.0861484969196135 0.9313483719244476 1.0 1.0 4 Q6PGP7 1 +Elevated circulating alanine aminotransferase concentration 0.3113739251443005 0.0828306837332216 0.9339861708620154 1.0 1.0 11 P10253,Q96RL7 2 +Myeloproliferative disorder 0.3577852726250762 0.0806957878573092 0.9356838866964452 1.0 1.0 3 P11274,Q01130 2 +Respiratory paralysis 0.3570265599727313 0.0797598986738244 0.9364282188911436 1.0 1.0 3 P36551 1 +Elevated urinary dicarboxylic acid level 0.3570265599727313 0.0797598986738244 0.9364282188911436 1.0 1.0 3 P36551 1 +Porphyrinuria 0.3570265599727313 0.0797598986738244 0.9364282188911436 1.0 1.0 3 P36551 1 +Axillary pterygium 0.3569421023046749 0.079656209288481 0.9365106886536184 1.0 1.0 3 Q15149,P23229 2 +Bilateral cleft lip 0.3569421023046726 0.079656209288478 0.9365106886536207 1.0 1.0 3 O60716,Q9NXE4 2 +Enlarged cisterna magna 0.2980469573251132 0.0781280644895704 0.9377261831853316 1.0 1.0 17 Q9H490,P49748,Q10713,Q9NPL8 4 +Aplasia hypoplasia of the sternum 0.3675091313047033 0.0780658069100148 0.9377757062923632 1.0 1.0 4 Q9Y619 1 +Melena 0.355536818437332 0.0779453288308875 0.9378715418740976 1.0 1.0 3 O00255,P46100 2 +Horizontal pendular nystagmus 0.2992413599325699 0.0766205426560348 0.9389254163158298 1.0 1.0 2 P37198 1 +Schistocytosis 0.3663794994791211 0.0764425479905267 0.9390670202108542 1.0 1.0 4 P41440 1 +Bone fracture 0.3565613300775837 0.0748227810840568 0.9403557159380144 1.0 1.0 6 Q13724,Q13126 2 +Aplasia hypoplasia involving the femoral head and neck 0.3107025094952452 0.0747137506074199 0.9404424668511988 1.0 1.0 10 Q96L58,Q96HY6,O75431 3 +Abnormal clavicle morphology 0.2905582096945575 0.0743998821855514 0.9406922025473672 1.0 1.0 22 O75844,Q14739 2 +Dysmetria 0.2812587700527258 0.0741033131583233 0.9409281789926722 1.0 1.0 58 Q9NPL8,Q10713,P20700,O75503,Q6DKK2,Q9Y4P3,Q8N183,O14773,O43292,O60313,O15121,Q6P4A7,Q8IV08 13 +Aphasia 0.2742424072738028 0.073680215152191 0.9412648420124368 1.0 1.0 40 P21964,P22626,Q7LGA3,O96008,P03886,P53701,Q9NX14,P05067,P00403 9 +Aplasia hypoplasia of the clavicles 0.2994686799230615 0.0711999610772585 0.943238612395674 1.0 1.0 14 O75844,P02545 2 +Distal upper limb amyotrophy 0.3023820349495895 0.0698543541590341 0.9443095844348326 1.0 1.0 13 Q9NR77 1 +Visual acuity test abnormality 0.3615406241214512 0.0696941238912869 0.9444371188662036 1.0 1.0 4 Q969G3,Q12824,Q99496 3 +Abnormal csf carboxylic acid concentration 0.3359594822735078 0.0678735166323712 0.9458863207894066 1.0 1.0 7 P36776,O00330,P51649,P08559,O00483,P10515 6 +Coarse facial features 0.2759683908066535 0.0667732598437472 0.9467622114387152 1.0 1.0 74 P10619,P51688,P38159,Q8TAQ2,P16278,P21281,Q969G3,Q8WVX9,Q8IWS0,P04066,Q96A33,P08236,O00255,P82930,Q7RTS9,Q96S52,P54802,P51812,Q7LGA3,Q9Y4P3 20 +Osteoporosis 0.2778232765400564 0.0647769716341823 0.9483515769071676 1.0 1.0 70 Q9HC21,Q9HC07,P35670,Q9Y4P3,Q9Y375,O95202,O43292,P16278,Q13510,P02545,Q5H8A4 11 +Abnormal renal tubule morphology 0.2856466595475921 0.0638285839500372 0.9491067179583784 1.0 1.0 24 P23786,P03886 2 +Narrow mouth 0.2730271681919817 0.0636650346290585 0.9492369465652672 1.0 1.0 78 Q8NCH0,P21964,Q7LGA3,O75844,P04062,Q9NVI7,Q6PGP7,Q15392,Q6NUK1,P02545,P16435 11 +Abnormality of the elbow 0.2797488173724161 0.0631047207746126 0.9496831151592776 1.0 1.0 63 P50402,Q7LGA3,O14656,Q7RTS9,Q969X5,P02545,Q13510,P37268,P23786,Q9BTV4,P16435 11 +Abnormal localization of kidney 0.2779862140921352 0.0621898403192606 0.9504116530808407 1.0 1.0 69 Q8NCH0,Q969G3,P18077,Q9UHX1,Q8TAA9,P51571,Q9Y4P3,P61313,P98175,Q9UBM7,Q6UX04,P16435 12 +Functional abnormality of the gastrointestinal tract 0.2739113970690318 0.0617482405354254 0.950763322844471 1.0 1.0 293 Q9NZJ7,Q14108,P55795,P53007,P01889,Q9UHX1,P51571,P35670,O15118,Q01105,O76024,Q6NUK1,Q9UBM7,Q01844,Q99720,Q86TI2,Q96RL7,P12235,P21964,Q12959,P49257,P82663,O14678,Q8N183,P21912,O95202,P08183,Q96A33,Q92581,P20700,P04062,P82930,Q6PGP7,P03886,Q13510,Q8IZA0,Q9UJS0,P16435,P00403,P61916,Q9NR77,P49748,P07602,P42892,Q6ZXV5,Q9Y4P3,P35637,Q14739,O60826,O60313,P05067,O15269 52 +Abnormal tricuspid valve physiology 0.2891357371043579 0.0613089267627725 0.951113181649152 1.0 1.0 21 O75431,P53701,Q9NX14,Q6NUK1,P40939 5 +Retinal arteriolar tortuosity 0.3071481274421683 0.0611789954541529 0.9512166575921452 1.0 1.0 9 P21964 1 +Obsessive compulsive behavior 0.2762598995953177 0.0611126681248683 0.9512694803046589 1.0 1.0 45 P55795,Q6DKK2,O75503,Q9Y4P3,P49589,Q96RL7 6 +Hip subluxation 0.3322421378385212 0.0598861761128729 0.9522462899973992 1.0 1.0 7 Q9UBM7 1 +Abnormal umbilicus morphology 0.2761318697245022 0.0568819585018227 0.9546392260709472 1.0 1.0 72 Q8NCH0,P21964,Q96T60,Q9NWM8,O75844,O14656,Q9Y4P3,Q8TAD8,Q9BUB7,Q14739,P02545,Q6NUK1 12 +Mild hearing impairment 0.2954128466194777 0.0558584609085734 0.95545456252669 1.0 1.0 14 O95140,P51812 2 +Retinal dystrophy 0.2791546918121585 0.054940750533238 0.9561856666577672 1.0 1.0 61 Q10713,P27635,Q5T8D3,P56589,Q8IY17,Q6P4Q7,P40855,Q8N2K0,O43837,O75381,P03886,Q16795,Q6UX04,O43505,Q8NHS3,P53701,Q9NX14,P38435,Q9Y287 19 +Angiofibromas 0.3475332739720289 0.054145064749603 0.9568195884054188 1.0 1.0 5 P21912 1 +Adenoma sebaceum 0.3475332739720289 0.054145064749603 0.9568195884054188 1.0 1.0 5 P21912 1 +Bronchitis 0.3120337830313943 0.0532791778082536 0.9575094703357894 1.0 1.0 8 Q03519,Q03518 2 +Abnormal pulmonary thoracic imaging finding 0.285177341555469 0.0521364386562843 0.9584199785864628 1.0 1.0 23 Q13510,P21964,P04062 3 +Pseudobulbar signs 0.3014851289501671 0.0512839040644296 0.9590992939220602 1.0 1.0 11 P17900 1 +Abnormal morphology of the limbic system 0.2968472643128865 0.0502497421771563 0.9599233730667276 1.0 1.0 13 Q01105 1 +Periventricular cysts 0.3273652738658875 0.0498024944678161 0.9602797788539654 1.0 1.0 7 O95202 1 +Femoral bowing 0.3029601112774808 0.0497981493420723 0.960283241466284 1.0 1.0 9 P16435 1 +Suicidal ideation 0.3279932546374442 0.0496777387899151 0.960379196423601 1.0 1.0 3 Q01082,Q14203 2 +Skin vesicle 0.2948561313392154 0.0434008372188962 0.965382010327536 1.0 1.0 13 P50336,Q9H488,Q14574,P16615 4 +Severe varicella zoster infection 0.338768625245996 0.0422815643612618 0.9662742416510026 1.0 1.0 4 O95394,P17812,Q9H0U3 3 +Spontaneous abortion 0.337644082091651 0.0411075141316886 0.9672101842578988 1.0 1.0 4 Q14191,Q9NQX3,P50570 3 +Atrophy degeneration involving the corticospinal tracts 0.2991587879927406 0.0409724574232316 0.9673178532097833 1.0 1.0 10 Q9Y4P3 1 +Muscular hypotonia of the trunk 0.2659072327579115 0.0403279298745546 0.9678316870662108 1.0 1.0 84 Q5BJH7,Q9NZJ7,P07602,Q2TAA5,Q9HC21,Q9NVI7,Q6ZXV5,P17900,Q5XKP0,Q96N66 10 +Renal fanconi syndrome 0.3153456998313726 0.0398176004565448 0.9682385442231698 1.0 1.0 3 P16930,Q9Y276 2 +Abnormal pleura morphology 0.2806781450284037 0.0382087368328687 0.9695212549987442 1.0 1.0 25 Q8NCH0,P01889,P36543,Q9H078,Q14739,Q6NUK1,P08236 7 +Steroid resistant nephrotic syndrome 0.335208098987632 0.0370731903652754 0.9704266483177526 1.0 1.0 5 Q8N1F7,Q8WUM0,Q12769,Q92621 4 +Pleural effusion 0.2946576151590728 0.0354928960041069 0.971686710975438 1.0 1.0 12 Q14739 1 +Abnormal nipple morphology 0.2770223650100256 0.0353225243667417 0.9718225626885796 1.0 1.0 62 Q2TAA5,Q7LGA3,O14678,Q96A33,Q9UM00,P10586,O95202,O60826,Q6NUK1,Q9UBM7,P23786,Q5H8A4 12 +Impotence 0.2972287590801993 0.0348891261577734 0.9721681514048216 1.0 1.0 9 Q969G3,P20700,O00255 3 +Erectile dysfunction 0.2972287590801993 0.0348891261577734 0.9721681514048216 1.0 1.0 9 Q969G3,P20700,O00255 3 +Diaphragmatic eventration 0.3311779589541772 0.0346706597714848 0.9723423569661896 1.0 1.0 4 P38935,O60568,P08243 3 +Widow s peak 0.3308968231655937 0.0344027667367845 0.9725559772424032 1.0 1.0 4 P21281,Q69YQ0,P29372 3 +Arterial thrombosis 0.332271589615712 0.032946943990716 0.9737168972064194 1.0 1.0 6 P01889 1 +Ileus 0.3285014603506857 0.0321600306934642 0.9743444305648788 1.0 1.0 4 Q01844 1 +Hypophosphatemia 0.3025612158739125 0.0314866403154365 0.9748814463473324 1.0 1.0 8 P51798,Q01968,O00255,O14745,P16930,Q6P1J9,P53680 7 +Hyperorality 0.3263986505482117 0.0302493866395622 0.9758681616901166 1.0 1.0 4 Q9UQN3,Q14203,P55072 3 +Polygenic inheritance 0.3295838020247493 0.0300316776884865 0.9760417894164716 1.0 1.0 5 P11274,P04637,P35658,P50454 4 +Pulmonary insufficiency 0.3300068588663862 0.0295328802112836 0.9764395957552936 1.0 1.0 6 P00813 1 +Abnormal sex determination 0.2982012366498112 0.0291964226898481 0.9767079342989552 1.0 1.0 3 Q14781,P51809 2 +Aplasia hypoplasia of the vagina 0.2982012366498106 0.0291964226898476 0.9767079342989556 1.0 1.0 3 P30153,P51809 2 +Sleep disturbance 0.2585190489494712 0.0276277300958011 0.977959064685182 1.0 1.0 166 P51812,Q7LGA3,Q8NHS3,P04062,Q9UHX1,O75503,Q96A33,Q9NVI7,O76024,Q01105,Q9UBM7,P49589,P50897,Q9NZ01,Q96N66,P54802,Q96RL7 17 +Lower eyelid coloboma 0.3230250210851829 0.0272959424556324 0.978223693115619 1.0 1.0 4 Q13428,Q15427,O15160 3 +Aplasia hypoplasia of fingers 0.2574725200817052 0.0266833082847021 0.978712326451968 1.0 1.0 109 Q03252,P27635,Q9UHX1,Q8TAQ2,P13073,Q6NUK1,Q9UBM7,Q5H8A4,Q969G3,Q15427,Q8IWS0,O95202,P51798,Q96S52,Q92796,P61313,Q13510,Q6UX04,P16435,P51812,P18077,Q96T60,O75844,O60826,P02545,P62847,P62854,P38435 28 +Abnormal calcium phosphate regulating hormone level 0.2917692953745479 0.0265452431934165 0.9788224474492616 1.0 1.0 12 O00255,P21912 2 +Movement abnormality of the tongue 0.3259854846836316 0.0257669307130066 0.979443238554585 1.0 1.0 5 P10253 1 +Abnormality of the choanae 0.2688681196080068 0.0235663353912578 0.9811985251553472 1.0 1.0 41 O75844,Q9UBM7,P16435,P02545 4 +Abnormal rectum morphology 0.2628001678049007 0.023528658043118 0.9812285789963672 1.0 1.0 35 Q9Y4P3,P51812,Q8TAA9,P21912 4 +Hyperparathyroidism 0.3235598355733745 0.0229962057866499 0.981653299493822 1.0 1.0 5 O00255,P53680 2 +Aplasia hypoplasia of the thyroid gland 0.3231158605174357 0.022498068712012 0.9820506525557876 1.0 1.0 5 Q13428,O14654,Q15738,O15160 4 +Death in adulthood 0.2863601298872436 0.0224834774839303 0.9820622917272752 1.0 1.0 15 Q92581,Q9Y4P3,P51812 3 +Abnormal shape of the palpebral fissure 0.2859478412554752 0.0209706658962896 0.9832690557518732 1.0 1.0 15 Q9UHX1 1 +Aplasia hypoplasia of the thymus 0.285630982146992 0.0198115414620982 0.9841937109357504 1.0 1.0 15 P21964,P00813 2 +Obstructive sleep apnea 0.2894941937782047 0.0196562098568791 0.9843176234955088 1.0 1.0 12 Q96A33 1 +Small cerebral cortex 0.2762788083192882 0.0195420113824089 0.9844087231965836 1.0 1.0 3 Q96SN8,Q15058 2 +Abnormal urine metabolite level 0.2582592975850551 0.0191137150171384 0.9847503904276284 1.0 1.0 165 Q14108,Q9NVI7,P35670,Q9BUB7,P16278,P23786,O14678,Q16134,O75431,Q96I36,P21912,Q5XKP0,P09601,O96000,P04062,Q6PGP7,P03886,P10253,P54802,P00403,P49748,Q9H078,Q9Y4P3,P02545,P40939,O95470 26 +Dilatation of the cerebral artery 0.2889927728792698 0.0181568554834711 0.9855137212933488 1.0 1.0 12 P38435 1 +Abnormal cerebral cortex morphology 0.2703308421241784 0.0166928187263879 0.9866816761903988 1.0 1.0 254 Q86XL3,O43924,Q10713,Q03252,Q9HC21,O76024,Q01105,Q9BUB7,P56589,P37268,Q9UBM7,P23786,Q96RL7,O60508,Q969G3,Q15427,O75503,Q16134,O96008,Q9Y3C6,Q9NZ01,Q9NWS8,Q15392,P40855,P51970,Q92581,P20700,O75381,P04062,Q9UPT5,P51572,P03886,O43819,Q9UM00,Q6UX04,P00403,Q2M389,O43505,P51812,Q96T60,Q7LGA3,Q9Y320,Q6ZXV5,Q9Y4P3,P35637,P05067,Q96N66 47 +Supernumerary nipple 0.2884680431318125 0.0165951579989839 0.9867595873846418 1.0 1.0 12 Q9UM00 1 +Abnormal thrombocyte morphology 0.2610694904676982 0.0159067418267384 0.9873087914836702 1.0 1.0 141 Q9NZJ7,Q14108,P21964,P07602,Q9HC07,P01889,P04062,P35670,Q6PGP7,O76024,Q14739,P61313,P00374,Q13510,P00813,O60508 16 +Focal impaired awareness seizure 0.2761899321291606 0.015850047041273 0.9873540216755106 1.0 1.0 26 P22466 1 +Abnormal cerebral vascular morphology 0.2726321850074302 0.0155790813053777 0.987570194358724 1.0 1.0 71 Q969G3,P00403,O75844,P04062,Q9Y4P3,O76024,P21912,P03886,P10253,P05067,P02545,P23786,P38435,P51970 14 +Abnormal gastrointestinal motility 0.2719355699700862 0.0152877825171011 0.987802589484808 1.0 1.0 30 O76024,P03886,P00403 3 +Diarrhea 0.2654533940251243 0.014220518241052 0.9886540504523932 1.0 1.0 82 Q13423,P42892,P03886,Q13510,Q9BT22,Q96A33,P40939,P54802,P00403 9 +Fair hair 0.3044700590385198 0.0133891149946043 0.9893173510408432 1.0 1.0 4 Q13724,P10644,Q05086 3 +Abnormal platelet aggregation 0.3044700590385146 0.0133891149946012 0.9893173510408456 1.0 1.0 4 P27797,Q86YV9,Q8N5K1 3 +Gray matter heterotopia 0.2636642601014268 0.0130820488456343 0.9895623329203094 1.0 1.0 37 Q86XL3,O43505,Q2TAA5,Q6ZXV5,Q9UBM7 5 +High anterior hairline 0.2760439708108571 0.0101111251026902 0.9919326268495664 1.0 1.0 24 O95202,Q92643,Q5H8A4 3 +Abnormal levels of alpha fetoprotein 0.3156118143459996 0.0097377700416005 0.992230506416643 1.0 1.0 6 P23229,Q15149,P16930,Q9UJS0,P35222 5 +Decreased circulating androgen concentration 0.2864672279046225 0.0090001405009943 0.9928190237955364 1.0 1.0 9 P16435 1 +Arachnoid hemangiomatosis 0.2913507420354668 0.0082194477681901 0.9934419033709452 1.0 1.0 8 P21912 1 +Hemangioblastoma 0.2913507420354668 0.0082194477681901 0.9934419033709452 1.0 1.0 8 P21912 1 +Retinal detachment 0.2822158172503123 0.0077892361148318 0.9937851516083444 1.0 1.0 16 Q8NCH0 1 +Hypertension associated with pheochromocytoma 0.2858001768559726 0.0074864337168908 0.994026745918724 1.0 1.0 9 P21912 1 +Abnormal granulocytopoietic cell morphology 0.292100084340738 0.0061309147304945 0.9951082684381204 1.0 1.0 4 Q01130,Q07020,O75533 3 +Chronic neutropenia 0.3025262973697627 0.0053911467384274 0.9956985080891548 1.0 1.0 7 O60508 1 +Aspiration 0.285070422535216 0.00440649121612 0.9964841400693534 1.0 1.0 11 P06865,O60231,P29372,Q69YQ0,O15344,P42356,Q9NQX3,P17900,P43243,O94979 10 +Elfin facies 0.3109115594733143 0.0039718001760006 0.9968309702929884 1.0 1.0 6 Q9Y4P3 1 +Morphological abnormality of the corticospinal tract 0.2840179512630176 0.0036547745500303 0.997083918305184 1.0 1.0 12 Q9Y4P3 1 +Atrioventricular canal defect 0.2839639947830698 0.0035012260831042 0.9972064314719444 1.0 1.0 12 Q9UBM7,Q9UHX1 2 +Respiratory failure requiring assisted ventilation 0.310267229254578 0.0032074920842719 0.9974407959752468 1.0 1.0 6 Q92734,P38935,Q9H9Y6,O75648,P10253 5 +Vitreous hemorrhage 0.3020247469066458 0.0019155255622637 0.998471632662704 1.0 1.0 5 P29992,P35222,Q99496,O75533 4 +Multifocal cerebral white matter abnormalities 0.3018937613876512 0.0018057896948025 0.9985591890655112 1.0 1.0 5 P10253 1 +Abnormality of the foot musculature 0.2816980601630606 0.0011267991037722 0.9991009445822252 1.0 1.0 4 O14979,P50570,Q8NCE2 3 +Pediatric onset 0.2680235514563593 9.89924389457698e-05 0.999921015461458 1.0 1.0 240 Q9NZJ7,P55795,Q99797,Q03252,Q10713,P28288,Q9NVI7,O15118,Q53H12,P16278,P22830,P23786,Q5BJH7,P50402,Q96CU9,P22466,Q8WVX9,P82663,Q9Y6M9,O75431,O95140,Q70HW3,Q8TB36,Q9Y6B6,Q5XKP0,P51970,P20700,Q2TAA5,Q14574,O43292,Q13510,P02545,Q96TA2,P54802,P41440,Q9NR77,P49748,P07602,P18077,Q8NHS3,Q9P0J0,P35241,Q9Y320,Q6ZXV5,Q9Y375,Q92643,Q8WWV3,O14773,P40939,P07196,Q9NPL8 51 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a400a394f29bc51b154bec1cece1ae0d55980be0 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil count", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating aldosterone", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rapid eye movement sleep", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the eustachian tube", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the 2nd finger", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Acute rhabdomyolysis", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical adenoma", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 2nd finger", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the 2nd finger", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous fistula", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar impression", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac rhabdomyoma", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral arteriovenous malformation", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Choroideremia", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic myelogenous leukemia", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Compensatory head posture", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical incisor", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased csf homovanillic acid", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased nasal nitric oxide", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to polysaccharide vaccine", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Decreased vigilance", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Dumbbell shaped long bone", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duodenal ulcer", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal autonomic seizure", "Focal aware seizure", "Focal clonic seizure", "Focal cognitive seizure with deja vu jamais vu", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Folliculitis", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucagonoma", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematochezia", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hypergastrinemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypoautofluorescent retinal lesion", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile cilia", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired renal concentrating ability", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Inappropriate sexual behavior", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased fibular diameter", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Insulinoma", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal carcinoid", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large cafe au lait macules with irregular margins", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphadenitis", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neonatal short limb short stature", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non convulsive status epilepticus without coma", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncommunicating hydrocephalus", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Palate fistula", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic endocrine tumor", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell adenoma", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Paraproteinemia", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid hyperplasia", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Peg shaped maxillary lateral incisors", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral arteriovenous fistula", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Photosensitive tonic clonic seizure", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior rib cupping", "Posterior subcapsular cataract", "Posterior uveitis", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged pr interval", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychic epileptic aura", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal polyposis", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Reflex seizure", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal angiomyolipoma", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged fingernail", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Sex reversal", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Silver gray hair", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Status epilepticus without prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral cleft lip", "Unilateral cleft palate", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced primary teeth", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP10", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG2", "AMPD2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANXA11", "AP1B1", "AP1S1", "AP1S2", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL6IP1", "ARPC1B", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG5", "ATG7", "ATIC", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7B", "ATRIP", "ATRX", "ATXN10", "AURKA", "B3GALT6", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCAT2", "BCKDHA", "BCKDK", "BCOR", "BCR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRIP1", "BUB1B", "BUB3", "C12orf57", "C16orf62", "C19orf70", "C1QBP", "C21orf59", "CAD", "CALD1", "CALR", "CAMK2G", "CAPN1", "CARS", "CASK", "CASP8", "CAST", "CBFB", "CBL", "CBX2", "CC2D1A", "CCDC22", "CCDC47", "CCDC8", "CCNK", "CCT5", "CD2AP", "CD320", "CDC40", "CDC42", "CDC45", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKN2A", "CELF2", "CEP250", "CEP290", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLIP1", "CLN5", "CLP1", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "CNP", "COA3", "COA7", "COASY", "COG4", "COG5", "COG7", "COG8", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COX14", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2A1", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CTU2", "CUL3", "CUL4B", "CWC27", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DBT", "DCAF8", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DEGS1", "DFFB", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIP2B", "DIS3L2", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJB11", "DNAJC13", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DPP9", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EPB41", "EPHA2", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EYA4", "EZR", "FAH", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GAL", "GALK1", "GALM", "GALNT2", "GAN", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLC", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNA11", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNS", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPRASP2", "GRHPR", "GSDME", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUSB", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF2BP2", "IGF2R", "IGHMBP2", "IKBKG", "IMPDH1", "INF2", "INPPL1", "INTS1", "INTS8", "IQCB1", "IRF2BPL", "IRS4", "ISCA2", "ITCH", "ITGA6", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIAA0319L", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF5C", "KIFBP", "KLC2", "L2HGDH", "LAMB1", "LAMC1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIG4", "LIN28B", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LRRC8A", "LRSAM1", "LSS", "LUZP1", "LZTFL1", "MACF1", "MAGED2", "MAGT1", "MALT1", "MAN2B1", "MAP1B", "MAP2K1", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED12", 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"POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QRICH1", "QRSL1", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "RELA", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNF2", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", 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1.96912334541656 0.0489389286133437 3.0097087378640777 8.393203883495145 0.4535126033788805 0.4859001261794073 1.6428435307790814 1.6853890758730747 0.9621453761461582 0.3132641846990659 1.0 1.0 1.0 0.6532622229061094 0.1594896243783859 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8103bd5846a4e6133f605af0a014581ab30cb77e --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 180, + "title": "Average number of proteins per term", + "value": 17.705555555555556 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6e2f1066b9251b252f807fe9888ebd743810b187 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ed69c0d4820b13db77bd74682f90b0ed5f2322e6 --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,58 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Parkinsons disease 0.654953688695629 3.537982321970571 0.0004031970518489 0.0700180525566335 0.0241918231109395 54 P14406,P21796,P45880,P13073,P15954,P12235,O14949,P05141,O43676,P08574,Q9Y6M9,Q9UDW1,P21912,O95168,P51970,O96000,Q9Y277,O75947,P03886,O75380,P24539,P00403,P22695,P12236 24 +Lysosome 0.6366049379384882 3.407362552681465 0.0006559393553822 0.1113997649737529 0.0260944640078984 55 Q9NZJ7,Q14108,P10619,P13473,Q93050,O15118,P16278,P11279,Q9UMR5,O75503,O43681,Q8NCC3,P50897,P11117,P04062,P10253,Q13510,P54802,P07602,Q8NHS3,P17900,O14773 22 +Cardiac muscle contraction 0.7962625252207 3.2896764307478636 0.0010030265242222 0.1652603344685709 0.0300907957266672 21 P05023,P14406,P00403,P16615,P09493,P08574,Q92581,Q9UDW1,P13073,P15954,O14949 11 +Huntingtons disease 0.5379429603513488 3.050334494096899 0.0022858662758795 0.33762731564649 0.0587794185226174 79 P14406,P21796,P45880,P13073,P15954,P12235,O14949,P05141,O43676,Q9Y6M9,P08574,Q9UDW1,P21912,O95168,P51970,O96000,Q9Y277,O75947,O75380,P24539,P00403,P22695,P12236,P06576 24 +Oxidative phosphorylation 0.5766858066869025 2.986116453569145 0.0028254502389595 0.3990844586156195 0.0635726303765893 60 P14406,Q93050,P13073,O75964,P15954,O14949,O43676,P08574,Q9Y6M9,Q9UDW1,P21912,O95168,P51970,P56385,O96000,Q86Y39,O75947,P03886,O75380,P24539,P00403,P22695 22 +Steroid biosynthesis 0.8773021245625112 2.783387418742605 0.0053794528212429 0.6212637976314845 0.1017275962976258 10 Q14534,Q15800,Q16850,Q15392,O76062,P37268,P48449 7 +Sphingolipid metabolism 0.7844036617555318 2.7048463811526657 0.0068335983344776 0.7089527843224498 0.1118225182005427 14 Q16739,O43681,P04062,Q9NRA0,P16278,Q13510,Q06136,O15121,O95470 9 +Alzheimers disease 0.5339969834360195 2.5928867575646133 0.0095174102809958 0.8211733266116863 0.1271367825390959 59 Q92542,P14406,P13073,P15954,O14949,O43676,P08574,Q9Y6M9,Q9UDW1,P21912,O95168,P51970,P16615,O96000,O75947,O75380,P24539,P00403,P22695,P14735,P06576 21 +Calcium signaling pathway 0.6785918134867698 2.5557890741649723 0.0105947318782579 0.8529857878094975 0.1271367825390959 20 P16615,Q9Y277,P21796,Q9NRA0,P45880,P12236,P12235 7 +Hypertrophic cardiomyopathy hcm 0.7981744075123193 2.4222255460065525 0.0154257730331499 0.9390851240948292 0.173539946622937 10 P50402,P16615,P02545 3 +Biosynthesis of unsaturated fatty acids 0.7184167168097918 2.114178111939671 0.0345000576006673 0.9981994491246576 0.2957147794342913 11 O95864,Q53GQ0,O00767,Q6Y1H2,Q9NZ01,P40939 6 +Snare interactions in vesicular transport 0.6273440467719867 2.0532503426255175 0.0400483041908688 0.9993619004659484 0.3276679433798356 17 Q9UEU0,Q9NZ43,Q12981,O60499,O15400,Q9P2W9,Q12846,Q5SQN1,Q86Y82 9 +Glycerophospholipid metabolism 0.6100525177521248 2.019756253555841 0.0434086768851589 0.9996605633744392 0.339720079970809 18 Q8NF37,Q9UG56,Q8NCC3,Q92604,Q96N66 5 +Dilated cardiomyopathy 0.7174292370306395 1.96912334541656 0.0489389286133437 0.9998804600672044 0.3670419646000777 9 P50402,P16615,P02545 3 +N glycan biosynthesis 0.6285853483501722 1.934993872074538 0.0529910476658554 0.9999445712333912 0.3715392451054088 15 Q2TAA5,P61803,P46977,P04843,Q8TCJ2,Q16706,Q13724,Q86YN1,Q9BT22 9 +Protein export 0.617208262137804 1.9295164504779465 0.053666779848559 0.999951254396051 0.3715392451054088 16 Q15005,P67812,Q15070 3 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.8329088887119525 1.881764083733718 0.0598680543703091 0.9999850725425348 0.3799045455016605 6 Q92643,O43292,Q5H8A4 3 +Glycosaminoglycan biosynthesis heparan sulfate 0.7507726889575617 1.7747296638918448 0.0759425348562885 0.9999993303985556 0.3835546689455732 2 Q7LGA3 1 +Glycosaminoglycan biosynthesis chondroitin sulfate 0.8406096340485575 1.7287417526875928 0.0838553250864528 0.9999998575930812 0.3835546689455732 3 Q8NCH0 1 +Abc transporters 0.6899291314635734 1.699306647527114 0.0892614207195645 0.999999950923668 0.3835546689455732 8 P28288,O14678,Q03518,P08183,Q03519 5 +Alpha linolenic acid metabolism 0.8255267776135928 1.667683015908284 0.0953786687153979 0.999999985410904 0.3849427232347361 3 O95864 1 +Porphyrin and chlorophyll metabolism 0.595257156745145 1.616641887293506 0.1059556046812497 0.999999998243552 0.3973335175546866 13 P09601,P30519,P22830 3 +O glycan biosynthesis 0.7562956868093819 1.4765253867946533 0.1398029052390108 0.999999999998311 0.4465934332146519 5 Q8N4A0,Q10472 2 +Cell adhesion molecules cams 0.5771097707797622 1.3856088528456136 0.1658663735197727 0.9999999999999932 0.4846857892424279 11 P04439,Q92896,P01889,P10586,P10321,Q9BY67 6 +Primary bile acid biosynthesis 0.6591739252598982 1.3478142833828497 0.1777181227222235 0.9999999999999994 0.4846857892424279 2 P51659 1 +Steroid hormone biosynthesis 0.7372992711203792 1.3072164837902194 0.191139198772428 1.0 0.5030596706419642 3 Q53GQ0 1 +Amyotrophic lateral sclerosis als 0.5721256545628601 1.3022248273141557 0.1928395404127529 1.0 0.5030596706419642 10 P07197,Q9BUN8,P07196,O96008 4 +Antigen processing and presentation 0.4937289160125589 1.2903673835895533 0.1969231310905339 1.0 0.5053804398590568 18 Q03519,P01889,P10321,P27824 4 +Ether lipid metabolism 0.6935086547187264 1.2153231636600632 0.2242428606216722 1.0 0.5381828654920132 5 Q8NF37 1 +Arachidonic acid metabolism 0.6952652536458004 1.1244214968283286 0.2608342566717936 1.0 0.5805280332240356 4 P09960 1 +Ecm receptor interaction 0.5909367842025728 1.032277023666891 0.3019423613898411 1.0 0.6120257785122973 7 Q08722 1 +Nicotinate and nicotinamide metabolism 0.6488970484693942 1.0298536837733483 0.3030786956168563 1.0 0.6120257785122973 5 P43490 1 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.4815684775100923 0.9752382503009412 0.3294420926155001 1.0 0.6412809183688163 13 P50402,P16615,P02545 3 +Folate biosynthesis 0.6358880317675941 0.8866450354133496 0.3752700392297181 1.0 0.6754860706134926 4 P00374 1 +Hematopoietic cell lineage 0.5554931160438223 0.8684718498915197 0.3851360762815996 1.0 0.6826718054624757 2 P23229 1 +Autoimmune thyroid disease 0.6116142724592288 0.7915619981077125 0.4286161125934367 1.0 0.7015623226984502 4 P01889,P10321 2 +Graft versus host disease 0.6116142724592288 0.7915619981077125 0.4286161125934367 1.0 0.7015623226984502 4 P01889,P10321 2 +Allograft rejection 0.6116142724592288 0.7915619981077125 0.4286161125934367 1.0 0.7015623226984502 4 P01889,P10321 2 +Renin angiotensin system 0.6071226980093207 0.7741703226262003 0.4388300758114933 1.0 0.7015623226984502 4 P10619 1 +Glycosaminoglycan degradation 0.5324800176687263 0.7701844128191399 0.4411905087024284 1.0 0.7015623226984502 7 P08236,P54802,P16278 3 +Peroxisome 0.3488653270361559 0.7583672538042123 0.4482311557903657 1.0 0.7015623226984502 36 Q9NR77,O43808,Q8WVX9,O75381,P28288,O14678,Q13011,O00116,P56589,P04179,Q9UKU0,O15254 12 +Proximal tubule bicarbonate reclamation 0.4676682009131137 0.6330915235231752 0.526673877328037 1.0 0.7404753618403822 8 Q9UBX3 1 +Ppar signaling pathway 0.3892503806828549 0.6127487316997752 0.5400424949471323 1.0 0.7404753618403822 18 O95864,O00767,Q9UKU0,P23786 4 +Limonene and pinene degradation 0.4890096478916426 0.5825787944254173 0.5601768840936825 1.0 0.74690251212491 7 P51648 1 +Type i diabetes mellitus 0.5064280304802283 0.4702830463951304 0.6381528083371304 1.0 0.8146631595793155 5 P10321 1 +Riboflavin metabolism 0.4218632857006844 0.4298089303422129 0.6673346361662136 1.0 0.8227413322597154 8 Q9NPH0 1 +Tryptophan metabolism 0.3638899308260746 0.3667352609630253 0.7138165019494047 1.0 0.8315983265802072 14 P40939,P51648 2 +Fatty acid metabolism 0.3250841788639217 0.3646636981391848 0.7153624598947634 1.0 0.8315983265802072 28 P49748,P40939,Q9BWD1,P23786,P51648,Q9UKU0 6 +Other glycan degradation 0.4318584137734328 0.3555852768730931 0.7221511712883073 1.0 0.8315983265802072 7 P04062 1 +Primary immunodeficiency 0.4715258034586955 0.351860396874502 0.7249429609753748 1.0 0.8315983265802072 5 P00813,Q03519 2 +Arginine and proline metabolism 0.3343353372954643 0.3394297879712611 0.7342859815707543 1.0 0.8315983265802072 22 P51648 1 +Vibrio cholerae infection 0.3381485069690204 0.3363611751131499 0.7365985233184968 1.0 0.8315983265802072 20 P24390 1 +Long term depression 0.3715492957746563 0.3206990148525767 0.7484384939221864 1.0 0.8315983265802072 11 P04899,Q02750,P30154,P30153,P27361,P63096,P08754,P29992,Q14344,P09471 10 +Thyroid cancer 0.3713400900900877 0.2820638643830939 0.7778945407126634 1.0 0.8486122262319965 9 Q92734,Q02750,P06753,P27361,P04637,Q16204,P35222,P12270 8 +Glycerolipid metabolism 0.3178349920074245 0.1151505502456021 0.9083257930456898 1.0 0.9505735043501404 12 Q9HCL2,Q53H12,P51648 3 +Aldosterone regulated sodium reabsorption 0.3473350301374295 0.0939230594145617 0.9251702760420976 1.0 0.9570726993538942 7 P05023,P54709,P05026 3 +Ribosome 0.2747316660011528 0.047568458443288 0.96206017007664 1.0 0.9895476035074012 73 Q02878,P39023,P27635,P61927,P84098,P18124,Q9BYD1,P62910,P62266,P46779,P62424,P46776,P47914,P40429,P61513,P46778,P62917,Q07020,P61313,P83881,P36578,Q9Y3U8,Q02543,P18077,P62241,P62847,P62854 27 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5030c7b4a78fc4640033776db35424b7f3b74a10 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTN1", "ACTN4", "ACVR1B", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "APIP", "APP", "APRT", "AQR", "ARF6", "ARFGAP1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKA", "B3GALT6", "B4GAT1", "BAIAP2", "BCAS2", "BCAT2", "BCKDHA", "BCR", "BDH2", "BET1", "BIRC6", "BLM", "BLVRA", "BNIP1", "BPNT1", "BRCA1", "BUB1B", "BUB3", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CAMK2G", "CANX", "CAPN1", "CAPN2", "CARS", "CASK", "CASP8", "CBL", "CBR1", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CD47", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2A", "CDS2", "CETN2", "CFL1", "CFL2", "CGN", "CHD8", "CHEK2", "CHERP", "CHKA", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "COASY", "COMT", "COX11", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPOX", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DBT", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DEGS1", "DERL1", "DFFA", "DFFB", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLG1", "DLST", "DNA2", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOLPP1", "DPM1", "DPYSL2", "DSG2", "DSP", "DTX3L", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERO1A", "ESPL1", "ETNK1", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FADS2", "FAH", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FPGS", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GBE1", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGA1", "GGA2", "GGCT", "GGH", "GGPS1", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPI", "GRB2", "GRHPR", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H1", "GTF2H4", "GTF2I", "GTSE1", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACL1", "HADH", "HADHA", "HADHB", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGF2BP1", "IGF2R", "IKBKG", "ILK", "IMPDH1", "IMPDH2", "INPP4A", "INPPL1", "IQGAP1", "IQGAP2", "IRS4", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITPA", "IVD", "JUP", "KARS", "KDELR1", "KDSR", "KEAP1", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARS", "LARS2", "LCMT2", "LDHA", "LDHB", "LDLR", "LGMN", "LIG1", "LIG3", "LIG4", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LYPLA1", "M6PR", "MAD2L1", "MAGED1", "MALT1", "MAN2A1", "MAN2B1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MFSD8", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPG", "MPI", "MPST", "MRE11", "MRPL13", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVB12A", "MVD", "MVK", "MYH10", "MYH14", "MYH9", "MYL6", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCBP1", "NCBP2", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEO1", "NF1", "NIT2", "NLN", "NME1", "NME3", "NNT", "NOTCH2", "NPC1", "NPC2", "NR3C1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NT5C2", "NT5C3A", "NTHL1", "NUDT5", "OAT", "OCRL", "OGDH", "ORC3", "ORC5", "OXA1L", "OXCT1", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDSS2", "PECR", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHF5A", "PHGDH", "PHKA1", "PHKB", "PHPT1", "PI4KA", "PI4KB", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PISD", "PKM", "PKN1", "PLA2G15", "PLCD3", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLXNA1", "PLXNB2", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "PPA1", "PPA2", "PPAT", "PPCDC", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP5C", "PPT1", "PPT2", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCZ", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTDSS1", "PTDSS2", "PTGES2", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "RAB13", "RAB23", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RABEP1", "RAC1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RALA", "RAPGEF2", "RARS", "RARS2", "RB1", "RBL1", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RBPJ", "RCOR1", "RDH11", "RDX", "RELA", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHEB", "RHOA", "RIPK1", "RNASEH2A", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRM1", "RRM2", "RUFY1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SCARB2", "SCD", "SCLY", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEPHS1", "SETD1A", "SETD2", "SETD7", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SGPL1", "SGSH", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC38A2", "SLC9A6", "SLIT2", "SLK", "SMAD4", "SMAP1", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNAP23", "SNAP29", "SNAP47", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOD2", "SORD", "SORT1", "SPCS2", "SPCS3", "SPHK2", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STIP1", "STMN1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SULT1A4", "SV2A", "SYMPK", "TAB1", "TAF10", "TAF2", "TAF6L", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TARSL2", "TBL1XR1", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM7SF2", "TMLHE", "TOLLIP", "TOMM40", "TP53", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TRA2A", "TRA2B", "TRAF2", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSC2", "TSG101", "TSPO", "TSTA3", "TTC37", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBR5", "UCK2", "UGCG", "UGDH", "UGP2", "ULK3", "UMPS", "UNC45A", "UNG", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USE1", "USP39", "USP8", "UXS1", "VAMP7", "VANGL1", "VAPA", "VARS1", "VARS2", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS25", "VPS28", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VTA1", "VTI1B", "WARS", "WARS2", "WASF2", "WASL", "WBP11", "WDR61", "XAB2", "XIAP", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX3", "YES1", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZFYVE16", "ZYX"], "leading_proteins": ["ABCB1", "ABCD3", "ABCD4", "ACADVL", "ACAT2", "ACOX3", "ACP2", "ACP6", "ACSL6", "ADA", "AGK", "AGPS", "ALDH3A2", "ALG1", "ALG11", "ASAH1", "ASNA1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5L", "ATP6V0A1", "BNIP1", "CADM1", "CANX", "CCDC6", "CD47", "CHST14", "CLN5", "COX2", "COX4I1", "COX7A2", "COX7C", "CPT2", "CTNNB1", "CTSA", "CYC1", "CYP51A1", "DAD1", "DEGS1", "DERL1", "DHCR24", "DHFR", "DOLPP1", "ECH1", "EMD", "FADS2", "FAR1", "FDFT1", "FECH", "GAA", "GALNT1", "GALNT4", "GBA", "GLB1", "GLG1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GPAA1", "GPAM", "GUSB", "HACD2", "HADHA", 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2.444020102096504 0.0145246172178088 4.300970873786408 9.604368932038836 1.1426576411245968 0.2560233101944223 2.515331441636984 1.9424437465598188 1.2133199793435778 0.2911424942178205 0.0417999766536677 1.0 0.16464692140167 0.0736296228832766 0.0016660348526245 +Complex i biogenesis 12 33 2.4428749843088853 0.0145707836866866 9.1747572815534 28.546116504854368 0.5440760559261008 0.4236381582634617 4.289696810672699 3.852285850983641 1.2631239118061712 0.3404380044043241 0.0156974236114754 0.2285159407722543 0.0156436233981126 0.0103180858249202 1.7595058433919238e-06 +Gpcr ligand binding 6 11 2.3993921069312 0.0164223186779624 3.4611650485436893 9.330097087378642 1.051447004644797 0.2131328881138611 1.5951828582954857 1.3192992367203638 1.3003237502897853 0.2397874119507845 0.0446798083571155 0.1918484459181316 0.3534667347825532 0.0231788170721074 0.0683826395880997 +Peptide ligand binding receptors 5 8 2.3885223747711226 0.0169162782331726 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0028771223664049 0.0755969254036216 0.1486636480545473 0.0005775014694085 0.0009601967587914 +Class a 1 rhodopsin like receptors 5 8 2.3885223747711226 0.0169162782331726 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0053496369295055 0.092554689717322 0.1803331870597798 0.0013478250121693 0.002692648903577 +Rac2 gtpase cycle 8 41 2.3395428511083005 0.0193073565570802 8.905339805825243 34.74757281553398 0.8419178475366841 0.4471774138928159 4.131135699306596 3.707034631516275 0.9898490308362274 0.3561406142763811 0.0129124825333969 1.0 0.5366634268489574 0.0123970480938125 0.0153386059693721 +Metabolism of steroids 18 54 2.3140299177871184 0.0206660811015657 11.16019417475728 45.26699029126213 0.7621248609364072 0.3994790342082778 4.702670999060317 5.049423467032678 1.2014135082145578 0.3371477938402821 2.1487013134922697e-08 0.0814990509318809 4.992081455854636e-05 1.301778714921925e-07 7.35181745673389e-08 +Synthesis of very long chain fatty acyl coas 4 9 2.312681043295802 0.0207401820255128 3.0800970873786406 7.662621359223301 0.2970725454313344 0.3790733377388842 1.7392923430670622 0.9085681268331954 1.2502564772465108 0.3141166423632316 0.0339972376759384 1.0 1.0 0.0005775014694085 0.0009601967587914 +Mitochondrial calcium ion transport 8 16 2.2966986691190927 0.0216359654309505 6.502427184466019 16.12135922330097 1.0650233237312683 0.2089377868120644 3.410790121717641 1.246287729205551 1.626144580445205 0.28031724173526 0.0501999052096723 0.0041305095198808 0.0163998244725808 0.0128055375372549 0.0003493380530507 +Post translational modification synthesis of gpi anchored proteins 3 8 2.292399006499012 0.0218826293075142 2.604368932038835 6.62378640776699 0.2821407958704103 0.5080023864003737 1.632878315136952 1.733932405097246 0.9567648693361852 0.309997386411001 0.4276775695775323 1.0 1.0 0.1755296958427615 0.0654507895325019 +Synthesis of pa 4 9 2.2730575457866946 0.02302271235018 2.9635922330097086 8.558252427184467 0.9129149199765416 0.2964837496518883 1.9473992387004595 1.904008254033093 1.1909456358572703 0.2923824193190221 0.0087962585732332 1.0 0.2108364442764713 0.0206613256108628 0.0060001681478776 +Metabolism of steroid hormones 3 7 2.246430098407642 0.0246764722516461 2.0606796116504853 5.754854368932039 0.472180937604631 0.3480370596589613 1.2262134961449431 0.9324780265795692 1.1891708581028433 0.2889255498989442 3.811917339060444e-05 1.0 0.0054453582128303 0.000131895504155 0.0019152907278613 +Transport of inorganic cations anions and amino acids oligopeptides 6 14 2.199942323946688 0.0278109873556382 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 0.0399573695699691 1.0 0.0643053609617777 0.0199990348372571 0.0178753363161684 +Unfolded protein response upr 7 40 2.197521823348239 0.0279831996308688 8.133495145631068 40.16990291262136 0.509262858744538 0.59689311184691 3.957191366627644 3.0048935800569123 0.762517577418289 0.3412893453215953 0.0404734839609984 0.2937526081992013 0.5093893069309869 0.102468551885206 0.0269782821702077 +Maturation of sars cov 2 spike protein 8 11 2.183629889831068 0.0289894553660454 4.405339805825243 10.808252427184469 -0.1344362046861288 0.501967252396237 2.5954161667653146 1.0701736790216847 1.0059681934825635 0.3121069900160693 1.0 1.0 1.0 0.4385111030432226 0.3218399169332961 +Rhod gtpase cycle 11 33 2.173792187810613 0.0297207455058721 7.283980582524272 27.854368932038835 0.3944337583042284 0.6115040287236689 3.4591142700991453 2.94828489550352 0.8000693972198841 0.3284465606650851 0.0549135737484515 1.0 1.0 0.006416673412216 0.0005462267667035 +Ras processing 2 5 2.1720265198035955 0.0298536626520249 1.3519417475728157 4.871359223300971 1.1011688928930974 0.2799307194914149 1.0191949595335985 0.8620674500492106 1.0561018280407846 0.2880746444526379 0.0039973815504214 0.0033831948266032 0.0007026031053852 0.0096601558647598 0.0603054088989602 +Mitophagy 2 13 2.1506642588020632 0.0315027093614495 3.662621359223301 11.783980582524272 1.3564301304992197 0.1917930287367771 1.8155907654273165 1.3363606860118669 1.2723890100166135 0.2636913304405313 0.0078387944068705 0.0001736135950622 0.0014183751228366 0.0184993148019339 0.0260591762772921 +N glycan trimming in the er and calnexin calreticulin cycle 5 15 2.1196220830440056 0.034037928638591 4.878640776699029 14.699029126213592 0.108355189317792 0.5779465857553798 2.939491749392236 1.3189062212723417 0.9052506944453566 0.3169163043543442 0.4276775695775323 1.0 0.2615377882636782 0.5369208791392233 0.4593968983428151 +Mitochondrial biogenesis 16 36 2.104566787877252 0.0353290351973976 10.572815533980584 33.521844660194176 0.7125383902440768 0.3998427377933914 4.798567629623383 2.9315837025395943 1.2191838320541302 0.3355715376706868 0.4331696412238679 0.3258864463602873 0.1906580163719264 0.3280842514657329 0.0024004575856903 +Synaptic adhesion like molecules 6 8 2.099188696116376 0.0358002700731032 1.6674757281553398 5.951456310679611 1.045730316736721 0.2890276876766184 1.4188777313077996 1.1438195320406324 0.8614150619700692 0.2468687149363868 0.1743886318517304 0.0495772435513037 0.0988756314725496 0.026793282710744 9.117164830587188e-05 +Glycosaminoglycan metabolism 6 17 2.0982130865340305 0.0358863260996014 6.563106796116505 14.388349514563108 0.750167459040055 0.1742505874253542 2.387954817808654 2.3973407990867264 1.8682770414846892 0.2409021330213527 0.3412654075955884 1.0 1.0 0.231214222216266 0.0502045920712355 +Pink1 prkn mediated mitophagy 2 9 2.05278592790226 0.0400933439167427 3.2815533980582523 8.473300970873787 1.395617281862234 0.1554977461962819 1.6230588150315317 0.9738153254376878 1.3577427922485954 0.2414588001366878 0.0028771223664049 5.966461606118925e-05 0.000499833948772 0.0070197321203344 0.0076060652236079 +Phase i functionalization of compounds 3 15 2.0518099744418823 0.0401881335676703 3.5364077669902914 14.184466019417476 1.0829555250605305 0.2802752482018614 1.63283502003666 1.0657744603346575 1.0337417132355466 0.2758879448139676 0.029336552338356 0.0138278109504967 0.0057841877037216 0.0132790770586149 0.1158015503640465 +Egr2 and sox10 mediated initiation of schwann cell myelination 2 8 2.014024165011898 0.0440069964647964 1.5631067961165048 6.456310679611651 0.9405466898133904 0.3504222949879002 1.1919625891097876 1.444955732376159 0.8981851290078471 0.2877478182828594 0.0459284510874455 0.0883440144706526 0.172526836456327 0.0805697230417203 0.068509275445109 +Pregnenolone biosynthesis 2 5 2.0130918478137696 0.0441049677015921 1.3155339805825244 3.815533980582525 0.3086691087192368 0.3696196218545987 0.9616185063516308 0.8532925699959941 1.227868587427035 0.2868560807038617 0.0002656754373321 1.0 0.0023675323812222 0.0006770655215996 0.005153499257652 +Rhog gtpase cycle 7 41 2.0057009111243165 0.0448881679538126 9.8373786407767 35.66504854368932 0.6614029400837433 0.4973720188279035 4.308521802053122 2.993429981792782 0.9950331841901028 0.3588671909523165 0.0340914373681064 1.0 1.0 0.0264745204980689 0.0200631156523385 +Depolymerisation of the nuclear lamina 3 9 1.985602770458412 0.0470774485980958 3.5509708737864076 9.264563106796116 0.3528590781344482 0.4868013249239434 1.8459675362212444 0.9401541669683848 0.9887999500170416 0.3159648114925705 1.0 1.0 1.0 0.3192924621263296 0.0060423314672148 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..469d011d91f49496ae4472c160276207f5e0d722 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 1412, + "title": "Average number of proteins per term", + "value": 20.903682719546744 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2f9aac9184a5bcf9726934eb88a3c3f88eca1a19 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f7c18287c41ee267861c725be348bba326da5f98 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,274 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Metabolism of lipids 0.5103548621750935 3.980131297901402 6.887721555259851e-05 0.0926780929965536 0.0032418209453423 210 Q9NZJ7,P10619,Q10713,Q16739,P09960,Q9NRA0,Q96G23,Q16850,P16278,Q06136,P37268,Q9UBM7,Q9UKU0,P23786,P48449,Q9UMR5,Q9UG56,Q8NCC3,Q53GQ0,O95772,Q15165,P50897,Q9NZ01,O00116,Q15392,O76062,O15121,Q12770,Q14849,Q8NF37,O95864,Q9BTU6,Q9P035,Q9HCL2,Q9NUQ2,Q9NQZ5,O43772,Q9H7Z7,P04062,Q6IAN0,Q92604,Q6Y1H2,O00767,Q9BWD1,P51648,Q13510,Q8N2A8,P49748,P07602,Q14534,Q9NPH0,Q15800,P27544,Q14739,P17900,Q8IV08,P30536,Q96N66,P40939,O95470,P38435 61 +Mitochondrial protein import 0.7253668776562897 3.6290308790934542 0.0002844872133702 0.3308540590905593 0.0077485835715597 33 Q10713,Q9NS69,O60830,Q99595,O14925,P08574,O43615,P21796,Q8N4H5,O75431,O96008,Q9Y5J6,P12236,Q9Y512,Q9NX63,Q9UJS0,P12235,Q13505 18 +Protein localization 0.6140592028124238 3.6233194327622704 0.0002908462672044 0.3368371297705323 0.0077485835715597 74 Q10713,Q9NS69,O60830,Q99595,P28288,O43615,P21796,Q9Y512,P46379,Q9NX63,P12235,O15254,P50402,O14925,P08574,Q8N4H5,O43681,O75431,O96008,Q8TB36,O00116,Q13505,P09601,O75381,P51648,Q9UJS0,Q9NR77,O43808,Q9Y5J6,P12236,Q13011,P14735,P06576,P05067 34 +Sphingolipid metabolism 0.7549538686384271 3.541633975830452 0.0003976568571499 0.429705937676311 0.0098507277595751 29 Q8N5B7,Q9NZJ7,P10619,P07602,Q16739,O43681,Q9NRA0,P04062,P27544,Q96G23,P51648,P16278,Q13510,Q06136,O15121,P17900,O95470 17 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.6207200997318078 3.4813183614767893 0.0004989520627272 0.5057412591396705 0.0115495133208331 66 P36542,P13073,O75964,P15954,O43674,O14949,P56134,O43676,P08574,Q9Y6M9,Q16134,Q9UDW1,P14927,Q8N183,Q96I36,P21912,O95168,P51970,O75880,P56385,O96000,Q86Y39,O75947,P03886,O75380,O43819,P24539,P00403,P22695,Q9P0J0,Q8TB37,Q9NX14,P06576,Q9Y375,Q9NPL8 35 +Respiratory electron transport 0.6052003457767592 3.181062159721394 0.0014673614161393 0.8742470400411777 0.0276255242611834 57 P13073,P15954,O14949,O43674,O43676,P08574,Q9Y6M9,Q16134,Q9UDW1,P14927,Q8N183,Q96I36,P21912,O95168,Q9Y6N1,P51970,O75880,O96000,Q86Y39,P03886,O75380,Q16795,O43819,P00403,P22695,Q9P0J0,Q8TB37,Q9NX14,Q9Y375,Q9NPL8 30 +The citric acid tca cycle and respiratory electron transport 0.5004565619255212 3.083910002687321 0.0020429938719648 0.9442934801819636 0.0360588418401792 99 P36542,P21796,O75964,P13073,P15954,O43674,O14949,P56134,O43676,Q9Y6M9,P08574,Q16134,Q9UDW1,P14927,Q8N183,Q96I36,P21912,Q9Y6N1,O95168,P51970,O75880,P35613,P56385,O43837,O96000,O95563,Q86Y39,O75947,P03886,O75380,Q16795,O43819,P24539,P00403,Q13423,P22695,Q9P0J0,Q8TB37,Q9NX14,P06576,Q9Y375,Q9NPL8 42 +Transport of small molecules 0.4527942117608353 3.065378701864558 0.0021739453910356 0.953715693089681 0.037726320683263 164 Q9GZP9,Q8WWC4,Q99797,Q10713,P28288,Q8N4V1,P21796,Q93050,Q9UJZ1,Q9H2J7,P45880,P35670,P30519,Q9H0U3,O15118,P56589,P33527,P49721,O75477,Q8WTV0,P12235,P05141,P36543,Q70HW3,P08195,Q9Y6B6,O95202,Q9BU23,Q9UNS2,P08183,Q9UBV2,P40855,P30825,P07237,P09601,P51798,Q9C0H2,P35613,P16615,Q92581,Q4KMQ2,Q9Y277,Q9UBI6,Q9Y6M7,P63218,P51665,Q9BUN8,Q96QD8,Q96TA2,P05023,P61916,Q8TB61,P12236,Q99623,Q9UBX3,P51790,Q9HD20,P27105,P28072,Q8WWI5 60 +Glycerophospholipid biosynthesis 0.6343938990187226 2.9986650707991496 0.0027116521922532 0.97837820743492 0.0435096919938812 33 Q8NF37,Q8N2A8,Q9HCL2,Q9UG56,Q9NQZ5,Q8NCC3,Q92604,Q9NPH0,Q96N66,P40939,Q8IV08 11 +Cristae formation 0.729923053330511 2.801967171830201 0.0050792041834757 0.99924599520248 0.0724427909804822 19 Q16891,P56385,P36542,O75431,Q9NVH1,O75947,Q9Y512,Q6UXV4,O75964,Q9NX63,P06576,Q5XKP0,P24539,Q13505 14 +Ire1alpha activates chaperones 0.6727248800916648 2.7596142351291792 0.0057869650897366 0.9997239502703672 0.0817119470670813 24 Q9Y5M8,Q9NWM8,P43307,O76024,O95070,O14773,P02545 7 +Slc mediated transmembrane transport 0.6708888742847972 2.748012419024943 0.0059957738008755 0.9997947977998634 0.0830003196748657 24 P53985,P05141,P35613,Q8TB61,Q9H2J7,Q70HW3,P08195,Q9Y6M7,P12236,Q9UBX3,Q8WWI5,P12235,Q96QD8,P30825,Q92581 15 +Sphingolipid de novo biosynthesis 0.797595407105861 2.674283289354026 0.0074889160338016 0.999975433908194 0.09701238018099 13 Q8N5B7,Q9NRA0,P27544,Q96G23,P51648,Q06136,O15121,O95470 8 +Acyl chain remodelling of pg 0.9418375948300056 2.6256934366838096 0.0086472659501231 0.9999952768619575 0.1068334698248008 2 Q8NF37 1 +Phospholipid metabolism 0.5446659047497334 2.6235829204541106 0.0087010262251077 0.9999956250298444 0.1068334698248008 54 Q8NF37,Q8N2A8,Q9BTU6,Q9HCL2,Q10713,Q9UG56,Q9NQZ5,Q8NCC3,Q92604,Q9NPH0,Q96N66,P40939,Q8IV08 13 +Initiation of nuclear envelope ne reformation 0.695757452281135 2.606286175395252 0.0091529952685305 0.9999977021565796 0.1104617890526932 19 P42167,Q86XL3,P50402,Q14739,P02545,O95067,Q86Y07,Q8IXJ6 8 +Glycosphingolipid metabolism 0.7309928317104114 2.5656896622470646 0.0102970909785136 0.9999995503820326 0.1191761677185346 16 Q9NZJ7,P10619,P07602,Q16739,P04062,P17900,Q13510 7 +Cholesterol biosynthesis 0.6758041949074394 2.5391934851302964 0.0111108357006637 0.9999998592537476 0.1265201613656225 20 Q14534,Q15800,Q9BWD1,Q16850,Q14739,Q15392,O76062,P37268,Q9UBM7,P48449 10 +Class i peroxisomal membrane protein import 0.7860769084057507 2.444020102096504 0.0145246172178088 0.9999999989337932 0.1570530272183322 11 Q9Y3D6,Q9NR77,O43808,O75381,P28288,Q8TB36,P51648,P56589,P40855 9 +Complex i biogenesis 0.559595762968408 2.4428749843088853 0.0145707836866866 0.99999999900204 0.1570530272183322 33 O43676,Q9Y6M9,O96000,Q9P0J0,Q86Y39,Q8N183,P03886,O75380,O95168,Q9Y375,Q9NPL8,P51970 12 +Gpcr ligand binding 0.7767663635049742 2.3993921069311996 0.0164223186779624 0.999999999929881 0.1682097525721111 11 Q9NZJ7,P22466,P07602,P42892,Q9NRV9,P05067 6 +Peptide ligand binding receptors 0.8411061848989076 2.3885223747711226 0.0169162782331726 0.999999999965502 0.1682097525721111 8 Q9NZJ7,P22466,P07602,P42892,Q9NRV9 5 +Class a 1 rhodopsin like receptors 0.8411061848989076 2.3885223747711226 0.0169162782331726 0.999999999965502 0.1682097525721111 8 Q9NZJ7,P22466,P07602,P42892,Q9NRV9 5 +Rac2 gtpase cycle 0.5257592023548879 2.3395428511083005 0.0193073565570802 0.999999999998892 0.1805429633019691 41 P42167,Q86XL3,P50402,Q8TAA9,O15173,Q14739,Q86Y07,Q13505 8 +Metabolism of steroids 0.5098133848793457 2.3140299177871184 0.0206660811015657 0.9999999999998436 0.1901632274027543 54 Q9HCL2,P30536,P04062,Q53GQ0,Q14534,O95772,Q15800,O00767,Q16850,Q14739,Q15392,O76062,P37268,Q9UBM7,Q12770,Q14849,P38435,P48449 18 +Synthesis of very long chain fatty acyl coas 0.790520836614075 2.312681043295802 0.0207401820255128 0.9999999999998594 0.1901632274027543 9 Q9P035,Q9UKU0,Q53GQ0,Q6Y1H2 4 +Mitochondrial calcium ion transport 0.6818395394104358 2.2966986691190927 0.0216359654309505 0.9999999999999614 0.1943287583786802 16 Q8WWC4,Q10713,Q9Y277,P21796,P45880,Q99623,O95202,Q96TA2 8 +Post translational modification synthesis of gpi anchored proteins 0.8193242375749281 2.2923990064990116 0.0218826293075142 0.9999999999999728 0.1943287583786802 8 Q92643,O43292,Q5H8A4 3 +Synthesis of pa 0.7819426586805992 2.2730575457866946 0.02302271235018 0.9999999999999948 0.1994360112788603 9 Q8NF37,Q8N2A8,Q9HCL2,Q9NPH0 4 +Metabolism of steroid hormones 0.8656326810539112 2.246430098407642 0.0246764722516461 0.9999999999999996 0.2001526684188693 7 P30536,Q14849,O95772 3 +Transport of inorganic cations anions and amino acids oligopeptides 0.6873061629667658 2.1999423239466873 0.0278109873556382 1.0 0.2085471315757917 14 Q70HW3,Q9Y6M7,Q9UBX3,Q96QD8,P30825,Q92581 6 +Unfolded protein response upr 0.5096401931000464 2.197521823348239 0.0279831996308688 1.0 0.2085471315757917 40 Q9Y5M8,Q9NWM8,P43307,O76024,O95070,O14773,P02545 7 +Maturation of sars cov 2 spike protein 0.7324465800748221 2.183629889831068 0.0289894553660454 1.0 0.2115354195011425 11 P27824,P61803,P46977,P04843,Q9H0U3,Q16706,Q13724,P14314 8 +Rhod gtpase cycle 0.5250851680039489 2.173792187810613 0.0297207455058721 1.0 0.2115354195011425 33 P42167,Q5JTV8,P50402,P20700,P49257,Q8TAA9,Q9Y6M7,O15173,Q14739,Q86Y07,P12814 11 +Chylomicron assembly 0.83843776341669 2.173394906723882 0.0297506078494533 1.0 0.2115354195011425 2 Q9Y6B6 1 +Plasma lipoprotein remodeling 0.8384377634166849 2.173394906723855 0.0297506078494553 1.0 0.2115354195011425 2 Q9BU23 1 +Ras processing 0.9283997716505408 2.1720265198035955 0.0298536626520249 1.0 0.2115354195011425 5 O43924,P49354 2 +Arachidonate production from dag 0.837875807811179 2.170881334740018 0.0299401436144153 1.0 0.2115354195011425 2 Q8NCG7 1 +Mitophagy 0.6943832230560937 2.1506642588020632 0.0315027093614495 1.0 0.2180481647959151 13 P21796,Q9NS69 2 +N glycan trimming in the er and calnexin calreticulin cycle 0.6615640427990063 2.1196220830440056 0.034037928638591 1.0 0.2310651694119735 15 Q9GZP9,P27824,Q13724,Q9BUN8,Q9UBV2 5 +Mitochondrial biogenesis 0.5007141222158404 2.1045667878772516 0.0353290351973976 1.0 0.2386822856398345 36 Q16891,P56385,P36542,O00411,O75431,Q9NVH1,O75947,Q9Y512,P04179,Q6UXV4,O75964,Q9NX63,P06576,Q5XKP0,P24539,Q13505 16 +Synaptic adhesion like molecules 0.7762671116661704 2.099188696116376 0.0358002700731032 1.0 0.240149253330034 8 P41440,O95197,O75955,Q12959,P10586,Q92796 6 +Glycosaminoglycan metabolism 0.6350254950732905 2.0982130865340305 0.0358863260996014 1.0 0.240149253330034 17 Q8NCH0,O43505,Q8TB61,P16278,Q8N6G5,P54802 6 +Vitamin d calciferol metabolism 0.921921420129658 2.0533415127607455 0.0400394673986115 1.0 0.2579347481706843 3 P04062 1 +Pink1 prkn mediated mitophagy 0.734968393159939 2.05278592790226 0.0400933439167427 1.0 0.2579347481706843 9 P21796,Q9NS69 2 +Phase i functionalization of compounds 0.6493721683819005 2.0518099744418823 0.0401881335676703 1.0 0.2579347481706843 15 P07099,Q16850,O43169 3 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.7575809539406259 2.014024165011898 0.0440069964647964 1.0 0.2707661495419481 8 Q9NR77,Q16850 2 +Pregnenolone biosynthesis 0.8881465268530258 2.0130918478137696 0.0441049677015921 1.0 0.2707661495419481 5 Q14849,O95772 2 +Rhog gtpase cycle 0.486573886713924 2.0057009111243165 0.0448881679538126 1.0 0.2726409101860093 41 P42167,Q86XL3,P50402,Q8TAA9,O15173,O95202,Q14739 7 +Regulation of tlr by endogenous ligand 0.8007867378477088 2.0037345114418965 0.0450985072998646 1.0 0.2726409101860093 2 P09429 1 +Depolymerisation of the nuclear lamina 0.7208714146629149 1.985602770458412 0.0470774485980958 1.0 0.2770052005856475 9 P42167,P50402,P02545 3 +Prostacyclin signalling through prostacyclin receptor 0.7960101152008968 1.982034356182484 0.0474753955677951 1.0 0.2770052005856475 2 Q9UBI6 1 +Inwardly rectifying k channels 0.7960101152008968 1.982034356182484 0.0474753955677951 1.0 0.2770052005856475 2 Q9UBI6 1 +Glucagon type ligand receptors 0.7960101152008968 1.982034356182484 0.0474753955677951 1.0 0.2770052005856475 2 Q9UBI6 1 +Presynaptic function of kainate receptors 0.7960101152008968 1.982034356182484 0.0474753955677951 1.0 0.2770052005856475 2 Q9UBI6 1 +Potassium channels 0.7960101152008968 1.982034356182484 0.0474753955677951 1.0 0.2770052005856475 2 Q9UBI6 1 +Proton coupled monocarboxylate transport 0.793481314976107 1.970530615430054 0.0487775897870783 1.0 0.2811181909361414 2 P35613 1 +Heme degradation 0.9026973760011172 1.9563811235788937 0.0504202741343027 1.0 0.2840073002587636 4 P30519 1 +Reactions specific to the complex n glycan synthesis pathway 0.7884237145265522 1.947491522795329 0.0514758350902115 1.0 0.2851392282985025 2 P04066 1 +N glycan antennae elongation in the medial trans golgi 0.7884237145265522 1.947491522795329 0.0514758350902115 1.0 0.2851392282985025 2 P04066 1 +Metabolism of porphyrins 0.7070493841892531 1.919253831681228 0.0549522177956207 1.0 0.2928020057638359 9 P09601,P30519 2 +Srp dependent cotranslational protein targeting to membrane 0.4046772708735426 1.885489906638404 0.0593637258846191 1.0 0.3028085197532254 93 Q15005,Q02878,P39023,P27635,Q9Y5M8,P51571,P61927,Q9UNL2,P61009,P84098,Q15629,P18124,P67812,P62266,P46779,P43307,P46776,P04843,P47914,P40429,P61513,P46778,P62917,P61313,P83881,P36578,Q9Y3U8,Q02543,P18077,P04844,P62847,P62854 32 +Formation of atp by chemiosmotic coupling 0.6994053939526816 1.8823611730577567 0.0597869938905117 1.0 0.3028085197532254 9 P56385,P36542,O75947,O75964,P06576,P24539 6 +Rhoa gtpase cycle 0.4574842641559308 1.845734115306095 0.064930821126333 1.0 0.3205675504558822 56 Q8NBN3,Q9P0I2,P41440,P42167,Q07021,O75955,Q9H0H5,P49257,P28288,Q14254,Q8TAA9,P51572,P30519,Q5T8D3,Q96HY6,O15173,Q14739,P27105 18 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.6639807336405255 1.8395247596657085 0.0658380395865791 1.0 0.3216723595025945 11 P09601,P50402,O43681,P46379,P51648 5 +Noncanonical activation of notch3 0.7617308232649527 1.825227415392033 0.0679667183090062 1.0 0.3252499301213387 2 Q92542 1 +Selective autophagy 0.4678792183899294 1.824909315585605 0.068014715216329 1.0 0.3252499301213387 35 P08670,Q8N4H5,P21796,Q9NS69 4 +Synthesis of pg 0.860859691150557 1.8103384155434616 0.0702433231829444 1.0 0.3291107929648083 3 Q8N2A8 1 +Protein protein interactions at synapses 0.5946214283107092 1.7975959189378703 0.0722410655472944 1.0 0.3291107929648083 16 P41440,O95197,O75955,Q12959,P10586,Q92796 6 +Cytochrome p450 arranged by substrate type 0.8533738569851517 1.7802280188934958 0.0750386517113579 1.0 0.3291107929648083 3 Q16850 1 +Abc transporters in lipid homeostasis 0.8392355255761679 1.7231886396222211 0.0848544174426924 1.0 0.3307686021451415 3 P56589,P28288 2 +Synthesis secretion and deacylation of ghrelin 0.8350752540627562 1.7063639950999256 0.0879403298563277 1.0 0.3338511884368265 3 P67812 1 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8350752540627562 1.7063639950999256 0.0879403298563277 1.0 0.3338511884368265 3 P67812 1 +Mitochondrial translation 0.439307828604168 1.6870953722170432 0.0915850147719008 1.0 0.3425282496647876 58 Q96GC5,Q9NWU5,Q96A35,Q9BYD1,Q9BRJ2,P82933,Q9BYD2,P82663,P49406,Q13084,Q9Y3B7,Q5T653,P82930,P82650,Q15070,Q9Y2R9,Q9HD33,Q7Z7H8,Q9BYN8,P82912,Q92665 21 +Effects of pip2 hydrolysis 0.8239863115257764 1.6614342891204488 0.0966262559871096 1.0 0.354379931048828 3 Q8NCG7 1 +Attachment of gpi anchor to upar 0.7971320725766488 1.644972616844918 0.0999754582040908 1.0 0.3601156810820822 5 Q92643,O43292 2 +Incretin synthesis secretion and inactivation 0.8227540951238905 1.639717599938982 0.1010638977858913 1.0 0.3612714523384266 4 P67812 1 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.8227540951238905 1.639717599938982 0.1010638977858913 1.0 0.3612714523384266 4 P67812 1 +Formyl peptide receptors bind formyl peptides and many other ligands 0.8170688102077222 1.6333471476688857 0.1023960060484041 1.0 0.3635090866407384 3 Q9NRV9 1 +Amino acid transport across the plasma membrane 0.7843082114735468 1.5922542421127186 0.1113275898661356 1.0 0.3727574617493375 5 P08195,Q96QD8,P30825,Q9H2J7 4 +Translation of sars cov 2 structural proteins 0.5403208348795133 1.588364079896954 0.1122040350250994 1.0 0.3736606072062274 18 P78362,P27824,P61803,P46977,P04843,Q9H0U3,Q16706,Q10472,P48729,Q13724,P14314 11 +Stimuli sensing channels 0.6123479481154974 1.5717963929798415 0.1159977783430992 1.0 0.3817922214929046 11 Q4KMQ2,Q9C0H2,P27105 3 +Transport of vitamins nucleosides and related molecules 0.7075298352601971 1.5599242677895424 0.1187777788730575 1.0 0.3885511954820436 7 P12236,P12235,Q8TB61 3 +Heparan sulfate heparin hs gag metabolism 0.7516174402250423 1.5435921686312253 0.1226871634173871 1.0 0.3945493217134861 6 P51688,Q7LGA3,P16278,P54802,P08236 5 +Synthesis of pc 0.7028759665817252 1.539076348636228 0.1237856582996277 1.0 0.3945493217134861 7 Q8NF37 1 +Integrin cell surface interactions 0.7700177697479242 1.5333059923694727 0.1252004788466201 1.0 0.3963930939136588 5 P35613 1 +Transport of bile salts and organic acids metal ions and amine compounds 0.7939274669665342 1.5238553935868795 0.1275448384080499 1.0 0.3984365306021384 4 P35613,Q8WWI5,Q9H2J7 3 +Rac3 gtpase cycle 0.4300393654184096 1.4979772965426787 0.1341391492098789 1.0 0.4065779120190524 39 P42167,P50402,Q8WUY9,Q15758,Q9H0H5,P49257,O75962,Q8TAA9,O15173,Q14739,Q13177,Q9UQB8,Q86Y07 13 +Receptor type tyrosine protein phosphatases 0.688957572351772 1.4872608279530424 0.1369459360877547 1.0 0.4105930718399325 2 P10586 1 +Mucopolysaccharidoses 0.7572374412580667 1.480427295744288 0.1387592500445009 1.0 0.4135464924796513 5 P08236,P54802,P16278 3 +Hs gag degradation 0.7826820354230988 1.478478390950526 0.1392797768192639 1.0 0.4135464924796513 4 P16278,P54802,P08236 3 +O linked glycosylation of mucins 0.7562956868093819 1.4765253867946533 0.1398029052390108 1.0 0.4135464924796513 5 Q8N4A0,Q10472 2 +O linked glycosylation 0.7562956868093815 1.4765253867946515 0.1398029052390113 1.0 0.4135464924796513 5 Q8N4A0,Q10472 2 +Rnd2 gtpase cycle 0.506042432731056 1.4640514126252082 0.1431799013758838 1.0 0.4159876970015391 20 Q8TAA9,P51648 2 +Endosomal vacuolar pathway 0.775653640708452 1.4500763050711625 0.1470372418778369 1.0 0.4233795694346796 4 P01889,Q9UIQ6,P10321 3 +G alpha i signalling events 0.4700919508578158 1.435322175200464 0.1511953115338673 1.0 0.42848909600121 26 Q9NZJ7,P22466,P07602 3 +Wax and plasmalogen biosynthesis 0.7401574803149342 1.4095604853189827 0.1586695017038621 1.0 0.4388996595160156 5 Q96K12,O00116,Q6IAN0,Q8WVX9 4 +Fatty acyl coa biosynthesis 0.5209139376134572 1.4076711171296006 0.1592284781389827 1.0 0.4388996595160156 17 Q9UMR5,Q9P035,Q53GQ0,Q6Y1H2,Q9NZ01,P50897,Q9UKU0 7 +Signaling by gpcr 0.4157876830467539 1.3939664647713583 0.1633277316994905 1.0 0.4422628974639349 47 Q9NZJ7,Q8NCG7,P22466,Q8N2K0,P07602,P51812,P42892,Q9NRV9,P05067 9 +G alpha q signalling events 0.5425852630312783 1.3904806125198048 0.1643829825318428 1.0 0.4422628974639349 14 Q8N2K0,Q8NCG7,P51812,Q9UBI6,P63218,P05067 6 +Maturation of sars cov 1 spike protein 0.7579716079480538 1.3785097769807804 0.1680459513433503 1.0 0.447699779805303 4 Q13724,P27824 2 +Pre notch processing in golgi 0.7569212193272765 1.3742543494166268 0.1693627331998488 1.0 0.4503581530662647 4 Q15363,P16615 2 +Arachidonic acid metabolism 0.5902640303047872 1.341757824408479 0.1796745312707899 1.0 0.4627303592503246 9 P09960,Q15165 2 +Nef and signal transduction 0.6577690362461323 1.3412338088513864 0.1798445527056431 1.0 0.4627303592503246 2 Q13177 1 +Interleukin 4 and interleukin 13 signaling 0.556046145363293 1.3329174613168024 0.1825588916763885 1.0 0.4669803533461242 12 Q07820,P09601 2 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.4731127242017943 1.3122882544598409 0.1894228936748003 1.0 0.4776203995937378 22 P07237,P11047,P19022,Q07065,Q8NBJ4,Q13217,O00255,P05067,O76024,O43852,Q02818,Q5JRA6,P14314 13 +Cation coupled chloride cotransporters 0.651587524585554 1.3122834293739265 0.1894245210853351 1.0 0.4776203995937378 2 P55011 1 +Calnexin calreticulin cycle 0.608145828305881 1.307515500704849 0.1910376939941898 1.0 0.4799737080423416 8 Q9GZP9,P27824,Q9UBV2 3 +Fatty acid metabolism 0.3986568450405526 1.3025640744974705 0.1927236294894199 1.0 0.4807979064765747 61 O95864,P49748,Q9UMR5,Q9P035,P09960,O43772,Q9H7Z7,Q53GQ0,P40939,Q15165,Q9NZ01,P23786,P50897,Q6Y1H2,O00767,P51648,Q9UKU0 17 +Apoptotic cleavage of cellular proteins 0.4801333291007416 1.2895526963698096 0.1972060087409479 1.0 0.4842103168542533 20 P08670,P49354,P20700,P02545 4 +Iron uptake and transport 0.4882485876340365 1.254911928407202 0.2095107332744845 1.0 0.5002898517114788 18 P09601,P30519 2 +Metabolism of folate and pterines 0.5703604469754214 1.241018670997342 0.2145988515907435 1.0 0.5033448146945679 9 P41440,Q9H2D1,P00374 3 +Er quality control compartment erqc 0.7197162368991469 1.235135749589198 0.2167799864152177 1.0 0.5051045228024547 3 Q9UBV2 1 +Intra golgi traffic 0.5153560218904614 1.2318418124436907 0.218008180843892 1.0 0.5062749974237578 14 O00461 1 +Nuclear envelope ne reassembly 0.3956164536071858 1.2233280631534065 0.2212058117984174 1.0 0.511199028247734 54 P42167,Q86XL3,P50402,Q9BTX1,Q14739,P02545,O95067,Q86Y07,Q8IXJ6 9 +Ra biosynthesis pathway 0.7102304665542479 1.1962916660240073 0.2315827598563675 1.0 0.5240302194185753 3 Q8TC12,Q8NBN7 2 +Class b 2 secretin family receptors 0.7089244670902887 1.190947246010568 0.23367429534213 1.0 0.5254464551381042 3 Q9UBI6 1 +Adrenaline noradrenaline inhibits insulin secretion 0.7112360898431289 1.1890497750310145 0.2344200805975269 1.0 0.5254464551381042 4 Q9UBI6 1 +G protein activation 0.7054525014052877 1.176744338679359 0.2392975649590663 1.0 0.5271266173513286 3 Q9UBI6,P63218 2 +Adp signalling through p2y purinoceptor 1 0.7056508293505712 1.1664320786009534 0.2434397950799378 1.0 0.5310746316077026 4 Q9UBI6,Q16539,P63218 3 +Translation of sars cov 1 structural proteins 0.6203027450832974 1.1655996316277433 0.243776356848649 1.0 0.5310746316077026 7 Q13724,Q10472,P27824 3 +The phototransduction cascade 0.7022870574960438 1.152818010686431 0.2489850902493731 1.0 0.5339703872924672 4 P49354 1 +Antigen presentation folding assembly and peptide loading of class i mhc 0.472436680773365 1.1522669544572917 0.249211391802929 1.0 0.5339703872924672 18 P27824,P01889,Q9NZ08,P51572,Q9Y6B6,P10321,Q03518,Q03519 8 +Activation of kainate receptors upon glutamate binding 0.6727429515645204 1.1288447773699744 0.2589633196643386 1.0 0.5443470501050499 5 Q9UBI6,Q92796,Q12959 3 +Rhoh gtpase cycle 0.4407911822223319 1.1195712701844784 0.2628965041426359 1.0 0.5483728292198297 23 P27105,Q8TAA9 2 +Neuronal system 0.3811039250454922 1.1044890823610156 0.2693810369076173 1.0 0.5525402023207749 59 O75915,P41440,O95197,O75955,P21964,Q12959,P51812,P07196,P10586,Q9UBI6,Q9Y639,Q92796,Q96QD8 13 +Striated muscle contraction 0.6482019275028184 1.1043205171842474 0.2694541257812353 1.0 0.5525402023207749 6 P09493,P08670 2 +Rhoj gtpase cycle 0.4204879800188433 1.085083013591252 0.2778848899314046 1.0 0.5637549778493438 27 Q9Y6M7,Q8TAA9,P27105 3 +Response to elevated platelet cytosolic ca2 0.3942494473416518 1.080223762167782 0.2800425493583129 1.0 0.5663436357587148 33 Q9NZJ7,P07602,Q92520,P13473,Q9BWS9,O43852,Q12846,Q6UXV4,P05067,O94919,P12814 11 +Unwinding of dna 0.5293998912473176 1.0795016350687918 0.2803641652941513 1.0 0.5663436357587148 10 Q9BRT9,Q9Y248 2 +Gaba receptor activation 0.640878685310629 1.0731721771554883 0.2831938716327236 1.0 0.5673173668645228 6 Q9UBI6,Q9Y639 2 +Basigin interactions 0.5583564065163916 1.0657039733794564 0.2865574809356741 1.0 0.571629969611701 8 P53985,P35613,P54709,P08195,P05026 5 +Peptide hormone metabolism 0.4824535897240091 1.0388958030067483 0.2988531985362594 1.0 0.585271451224963 14 P61009,Q15005,Q9UPT5,P67812 4 +Sars cov 2 infection 0.4173746530888542 1.0334315458223864 0.3014019900965392 1.0 0.5886301659976672 26 P78362,P27824,P61803,P46977,P04843,Q9H0U3,Q16706,Q10472,P48729,Q13724,P14314 11 +Wnt ligand biogenesis and trafficking 0.6304748175357601 1.0289892667847018 0.3034847185487312 1.0 0.5910626518493911 6 Q5T9L3 1 +Plasma lipoprotein assembly remodeling and clearance 0.460574932427142 1.0270328045429615 0.3044050173987536 1.0 0.5920384084945455 17 P61916,O15118,Q9Y6B6,Q9BU23,Q8WTV0 5 +Rhoc gtpase cycle 0.3768062163737354 1.008885035626238 0.3130297726988478 1.0 0.598913332047118 39 P42167,P41440,Q07021,O75955,P49257,P28288,Q14254,Q8TAA9,Q5T8D3,Q14739,P27105 11 +Processing of smdt1 0.5061484034256223 1.0056809685627095 0.3145690608816811 1.0 0.599726105650045 11 P35232,Q8WWC4,Q8IYU8,Q10713,Q9UJZ1,Q99623,Q9Y4W6,Q96TA2 8 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.510975016846124 0.9833879309720456 0.3254165479822815 1.0 0.6126508876679753 10 Q92796,Q12959,P51812 3 +Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.6595445600224896 0.9807121329891296 0.3267347189580525 1.0 0.6126818368775738 4 O14734,P51659,O14975 3 +Beta oxidation of pristanoyl coa 0.6595445600224741 0.980712132989068 0.3267347189580829 1.0 0.6126818368775738 4 O14734,P51659,O15254 3 +Glutamate neurotransmitter release cycle 0.6587017953878898 0.9773424058443818 0.3283996658159145 1.0 0.6133602223969197 4 Q96QD8 1 +Ionotropic activity of kainate receptors 0.6506867185306527 0.9544576208286694 0.3398520512863421 1.0 0.6277447261587852 3 Q12959 1 +Nrcam interactions 0.6506867185306527 0.9544576208286694 0.3398520512863421 1.0 0.6277447261587852 3 Q12959 1 +Cargo concentration in the er 0.4603937774765413 0.9440472622487232 0.3451454971697241 1.0 0.6312418941160173 15 Q13190,Q12907,P49257,P49755,Q9Y6B6,Q15363,Q5JRA6,O75396,Q96PC5 9 +Aflatoxin activation and detoxification 0.6480639546049402 0.9439365045741412 0.3452020962656648 1.0 0.6312418941160173 3 Q99735 1 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.6253375998113094 0.932709303452348 0.3509700800507316 1.0 0.6346307211958891 5 P12236,P12235 2 +Synthesis of pips at the golgi membrane 0.5307694746889018 0.9320419807355208 0.3513148302994695 1.0 0.6346307211958891 8 Q9BTU6,Q10713 2 +Rnd1 gtpase cycle 0.4381598194209414 0.9287836041704158 0.3530012431356586 1.0 0.6357624429943239 18 P51648 1 +Plasma lipoprotein clearance 0.471363080919593 0.9172540961134976 0.3590095055774625 1.0 0.6387272383808009 13 Q8WTV0 1 +Sialic acid metabolism 0.6204777913231808 0.912787948329191 0.3613540779318449 1.0 0.6387272383808009 5 P10619 1 +Long term potentiation 0.6024802613488311 0.9107388275437732 0.3624330007966405 1.0 0.6387272383808009 6 Q92796,Q12959 2 +Ras activation upon ca2 influx through nmda receptor 0.6024802613488311 0.9107388275437732 0.3624330007966405 1.0 0.6387272383808009 6 Q92796,Q12959 2 +Unblocking of nmda receptors glutamate binding and activation 0.6024802613488311 0.9107388275437732 0.3624330007966405 1.0 0.6387272383808009 6 Q92796,Q12959 2 +Sulfur amino acid metabolism 0.4969033221177872 0.9101939697340724 0.3627202238130618 1.0 0.6387272383808009 10 Q13126,Q9UBX3 2 +Purinergic signaling in leishmaniasis infection 0.6198118789808196 0.9100619614880996 0.362789833697877 1.0 0.6387272383808009 5 P09601 1 +Biological oxidations 0.3654676232855147 0.9028672199488544 0.3665963699408177 1.0 0.6430236948527137 46 P21964,O43169,Q8TB61,P0DMN0,P07099,Q9NUJ1,Q16850,P16435 8 +Chondroitin sulfate dermatan sulfate metabolism 0.6144175247904183 0.8880147883611268 0.3745327965511329 1.0 0.6459027896381486 5 Q8NCH0 1 +Rho gtpase cycle 0.3042148480109638 0.8742155466632774 0.3820008810842132 1.0 0.6497010840320715 174 Q9P0I2,Q8NBN3,Q86XL3,Q15758,Q15058,Q5JTV8,P28288,P38159,Q14254,Q8TAA9,P30519,Q5T8D3,Q9Y512,P50402,P08670,Q07021,Q9H0H5,P49257,Q96HY6,O95202,Q9UQB8,Q07065,Q86YQ8,Q13505,P62995,O75955,P20700,Q96CS3,P51572,Q9NYL9,Q9Y6M7,P51648,P42167,P41440,Q14185,O15173,Q14739,P27105,Q86Y07,Q13813,P12814 41 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.5928170981203909 0.8702318451936771 0.3841737161697889 1.0 0.6501448555604027 6 P04439,P01889,P10321 3 +Ptk6 regulates cell cycle 0.5552121382410686 0.8672102296993199 0.3858268322723317 1.0 0.6508090292314549 2 P24941 1 +Signaling by nodal 0.6069234879600494 0.8574981848591042 0.3911696175350054 1.0 0.6559756531584652 5 P36896 1 +Signaling by activin 0.6069234879600494 0.8574981848591042 0.3911696175350054 1.0 0.6559756531584652 5 P36896 1 +Runx1 regulates expression of components of tight junctions 0.544534981736433 0.8195325484711241 0.4124826396040859 1.0 0.6746755810616815 2 Q07157 1 +Elastic fibre formation 0.5436920483281711 0.8157916337858513 0.4146193190351925 1.0 0.6746755810616815 2 P55081 1 +Molecules associated with elastic fibres 0.5436920483281711 0.8157916337858513 0.4146193190351925 1.0 0.6746755810616815 2 P55081 1 +Nuclear envelope breakdown 0.3566063767421696 0.8147482035206773 0.4152164551040642 1.0 0.6746755810616815 44 P42167,P50402,Q9BTX1,P20700,O95067,P02545,O15504,Q86Y07,Q8TEM1 9 +Inla mediated entry of listeria monocytogenes into host cells 0.5425681371171605 0.810809311467336 0.4174751863333485 1.0 0.6746755810616815 2 O60716 1 +Synthesis of bile acids and bile salts 0.5414188739209003 0.8097417428562841 0.4180886214086199 1.0 0.6746755810616815 7 P51659,Q96SU4,Q9BXW6,O14975,O14734 5 +Bile acid and bile salt metabolism 0.5414188739209003 0.8097417428562841 0.4180886214086199 1.0 0.6746755810616815 7 P51659,Q96SU4,Q9BXW6,O14975,O14734 5 +Shc1 events in erbb2 signaling 0.5411632481033946 0.804590483529791 0.4210560355351926 1.0 0.6771465596909049 2 Q05655 1 +Inflammasomes 0.5723992758440539 0.7853914232814847 0.4322241078366635 1.0 0.678947130377306 6 P09601 1 +The nlrp3 inflammasome 0.5723992758440539 0.7853914232814847 0.4322241078366635 1.0 0.678947130377306 6 P09601 1 +Neurotransmitter release cycle 0.4961769163724061 0.7663967357743465 0.4434402744832768 1.0 0.6863999507809094 8 Q96QD8 1 +Trafficking and processing of endosomal tlr 0.5313290250070137 0.7613565397959678 0.446444138344038 1.0 0.6867498350183164 2 Q99538 1 +Alpha oxidation of phytanate 0.5824939934800931 0.759117355038728 0.4477823582508082 1.0 0.6867498350183164 5 P51648 1 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3987043496702837 0.7568714245230614 0.4491268966135084 1.0 0.6867498350183164 21 Q86YN1,Q9BT22,P10619,P16278 4 +G alpha z signalling events 0.5636762700836957 0.7495263820871951 0.4535400035752277 1.0 0.6882643200884296 6 Q9UBI6 1 +Adp signalling through p2y purinoceptor 12 0.5757450715770083 0.7322937365101426 0.463989301498938 1.0 0.6984572427681242 5 Q9UBI6 1 +Gaba b receptor activation 0.5757450715770083 0.7322937365101426 0.463989301498938 1.0 0.6984572427681242 5 Q9UBI6 1 +Rhoq gtpase cycle 0.3762071069595042 0.7166866435674107 0.4735674690425751 1.0 0.7083281909212873 26 P27105,Q8TAA9 2 +Dap12 interactions 0.5674632186636828 0.6996260781533759 0.4841608521391356 1.0 0.716709978237871 5 P10321 1 +Slc transporter disorders 0.34181799754417 0.6985726723652442 0.4848191269285367 1.0 0.716709978237871 35 P53985,P35613,Q9BTX1,Q8N1F7,Q92621,P37198,A8CG34,P08195,P12270,O15504,Q7Z3B4,Q8TEM1,Q92581 13 +Cobalamin cbl vitamin b12 transport and metabolism 0.5498019091335832 0.6930583599142346 0.48827292789355 1.0 0.7176564136701888 6 P33527,P22033,O14678 3 +Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0.5133464456307837 0.6838229341712545 0.4940869827027763 1.0 0.7229542171775338 2 Q13951 1 +Pyruvate metabolism 0.4021057793845227 0.6583000471744264 0.5103453476870885 1.0 0.7368176185420952 17 P35613,P21796 2 +Potential therapeutics for sars 0.339169777108071 0.651655253909996 0.5146235945565687 1.0 0.7384639385303607 41 P49354,P21964,Q99720 3 +Signaling by erbb4 0.5026160841973847 0.6402819982717205 0.5219892819377692 1.0 0.7452465784591811 7 P46934 1 +Diseases associated with n glycosylation of proteins 0.5353579420599993 0.635158502645806 0.5253250447583437 1.0 0.7458151506829408 6 Q9BT22,O75352,Q2TAA5 3 +Negative regulation of nmda receptor mediated neuronal transmission 0.4986239399048781 0.6232406161345397 0.5331264148355273 1.0 0.749427209122863 7 Q92796,Q12959 2 +Cdc42 gtpase cycle 0.3325270224060967 0.6089674407831518 0.5425460204429469 1.0 0.756658345054197 36 P27105,Q14739,Q8TAA9 3 +Autophagy 0.3335775589402895 0.6060093390168118 0.5445085517296966 1.0 0.7569673301641665 59 P08670,Q9NS69,Q8N4H5,P13473,P21796 5 +Chaperone mediated autophagy 0.494515086927379 0.6057952073556122 0.5446507526414206 1.0 0.7569673301641665 7 P13473 1 +Activation of gene expression by srebf srebp 0.36990414561968 0.6049541344719624 0.5452094722216412 1.0 0.7569673301641665 23 Q9HCL2,Q14534,O00767,Q16850,O76062,P37268,Q9UBM7,P48449 8 +Regulation of cholesterol biosynthesis by srebp srebf 0.3465909837117055 0.6015111510041709 0.5474995869251762 1.0 0.7579111928807342 31 Q9HCL2,Q14534,Q16850,O76062,P37268,Q9UBM7,Q12770,P48449 8 +Peroxisomal lipid metabolism 0.4146792772360094 0.6004361014246262 0.5482156340824416 1.0 0.7581591335204775 13 O43808,Q5T8D3,Q9BY49,P51648,O15254 5 +Keratan sulfate keratin metabolism 0.5408568804480867 0.5968690661171442 0.5505948016235811 1.0 0.7607043638869829 5 P16278 1 +Neutrophil degranulation 0.2907840550465235 0.5956328932233745 0.5514204974863748 1.0 0.7611004325031879 184 Q92542,Q9NZJ7,P10619,P09960,P13473,Q93050,P01889,O15260,Q969Q5,P30519,P10321,P16278,P11279,Q5T9A4,O43681,Q08722,Q07065,O15121,P42785,Q8NF37,Q4KMQ2,Q9H7Z7,O00264,P10253,Q13510,P07602,P12956,Q99536,P17900,P27105 30 +G alpha s signalling events 0.5217184910113603 0.5814680650874594 0.5609250353087547 1.0 0.765982736804605 6 Q9UBI6 1 +Cd28 dependent pi3k akt signaling 0.4852486653554299 0.567563419810502 0.5703314517661615 1.0 0.7698929348889542 2 P42345 1 +Runx2 regulates genes involved in cell migration 0.4852486653554279 0.5675634198104931 0.5703314517661675 1.0 0.7698929348889542 2 Q13951 1 +Regulation of gene expression in beta cells 0.4852486653554231 0.5675634198104748 0.5703314517661799 1.0 0.7698929348889542 2 O00330 1 +Rhof gtpase cycle 0.3683331936218061 0.5482996626837473 0.5834861589781095 1.0 0.78019172014876 21 P42167,Q5JTV8,P20700,Q8TAA9,Q9Y6M7 5 +Other semaphorin interactions 0.4801910649058633 0.547390997442408 0.5841101388588439 1.0 0.7802871485985691 2 P05556 1 +Synthesis of substrates in n glycan biosythesis 0.3859924377590696 0.5303918415138981 0.5958402813957155 1.0 0.7907203734311563 16 Q86YN1,P10619 2 +Notch3 activation and transmission of signal to the nucleus 0.5351586293302104 0.5159608976562409 0.6058817197708342 1.0 0.8001397447793794 3 Q92542 1 +Fbxw7 mutants and notch1 in cancer 0.4717617308232557 0.5143530296505525 0.6070051922323365 1.0 0.8001397447793794 2 Q13616 1 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.4011069369057881 0.4910407291972878 0.6233976409850204 1.0 0.8165468173198969 12 O60725 1 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.5238898257448076 0.4774179230613335 0.6330645539278654 1.0 0.8223432844030781 3 Q16539,P54619 2 +Cargo trafficking to the periciliary membrane 0.356874951104918 0.4713951081185706 0.637358608694379 1.0 0.8241743577269252 21 O43924,Q10713 2 +Lipophagy 0.5240371099240957 0.4702422770799432 0.6381819324042604 1.0 0.8244399712303894 4 O60664,P11142,P54619 3 +Interconversion of nucleotide di and triphosphates 0.3693994404530977 0.4591236444841963 0.6461453781980206 1.0 0.8301704040178391 17 Q9H773,Q9UIJ7 2 +Ion channel transport 0.3218012768941124 0.4494889460574101 0.6530789803866641 1.0 0.8360358298331548 33 P05023,Q4KMQ2,Q9C0H2,P16615,Q93050,P35670,Q9HD20,P27105 8 +Defects in cobalamin b12 metabolism 0.5001947394326358 0.4483173361809915 0.6539241908212841 1.0 0.8363595628982364 5 P22033,O14678 2 +Diseases of glycosylation 0.3514450207275423 0.4354440251225587 0.6632401603448199 1.0 0.8429298887550727 21 Q8NCH0,P10619,Q2TAA5,P16278,Q9BT22 5 +Diseases of carbohydrate metabolism 0.4013635223566146 0.4332275258315746 0.6648494836023007 1.0 0.8432718334721234 10 P54802,P10253,P16278 3 +Rhobtb3 atpase cycle 0.4946569178852744 0.4290820407522215 0.6678635214281372 1.0 0.8442464568097849 5 O60664,O14964,P51151,Q13618 4 +Pyruvate metabolism and citric acid tca cycle 0.3110024789581851 0.4215506446285528 0.6733530377424806 1.0 0.8489057940110558 35 Q13423,P35613,P21796,P21912 4 +Sars cov 1 infection 0.3676131860092947 0.4033970779883211 0.6866561359977819 1.0 0.8557444519230962 15 Q13724,Q10472,P27824 3 +Plasma lipoprotein assembly 0.4999062613161166 0.3991591159140913 0.6897759658780878 1.0 0.8573623801231162 3 Q9Y6B6 1 +Visual phototransduction 0.3943400257090115 0.3786277291297328 0.7049643277854842 1.0 0.8663269197851208 9 Q6NUM9,P49354 2 +Cytosolic sulfonation of small molecules 0.4792342240919627 0.3770043266940078 0.7061703895284404 1.0 0.8670544260992676 5 Q8TB61 1 +Meiotic synapsis 0.3499203919537133 0.3699098337717028 0.7114496740731115 1.0 0.8709474390425234 18 P20700,Q9UH99,P02545 3 +Pre notch expression and processing 0.3760040720763901 0.3663845321079848 0.7140781601296022 1.0 0.8709474390425234 12 Q15363,P16615,Q9UBV2 3 +G beta gamma signalling through pi3kgamma 0.4914377920554835 0.3644858335708342 0.7154952505244545 1.0 0.8709474390425234 4 Q9UBI6 1 +Ecm proteoglycans 0.4893373598180168 0.3580222661152585 0.7203266505817747 1.0 0.8751788805398669 4 P05067 1 +Runx3 regulates p14 arf 0.4845418774592537 0.352060179328325 0.7247931312226994 1.0 0.8753198770744518 3 P25440,Q13951 2 +Organelle biogenesis and maintenance 0.2800219860018718 0.3331637110284962 0.7390107092080802 1.0 0.8846299945221081 105 Q16891,O43924,Q10713,P36542,O00411,O95684,Q9NVH1,Q9Y512,O75964,Q9NX63,O94927,O75935,P56134,O75431,P41208,Q5XKP0,Q13505,P56385,Q9UPT5,O75947,A6NIH7,P24539,Q96CS2,Q6UXV4,P06576,P04179 26 +Metabolism of fat soluble vitamins 0.4530952379353573 0.3319771246945178 0.7399065322454743 1.0 0.8846299945221081 6 Q8N0U8 1 +Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.4197808373138475 0.3299797910425521 0.7414152320852008 1.0 0.8849351713476784 2 P52292 1 +Camk iv mediated phosphorylation of creb 0.4197808373138475 0.3299797910425521 0.7414152320852008 1.0 0.8849351713476784 2 P52292 1 +Dopamine neurotransmitter release cycle 0.4161281258780546 0.3184822335742595 0.750119169175469 1.0 0.8930592469441502 2 Q13136 1 +Platelet activation signaling and aggregation 0.304764660707909 0.3040706208501721 0.7610740889039396 1.0 0.9022977443596664 57 Q8N2K0,Q8NCG7,Q9NZJ7,Q9UEU0,P07602,Q92520,P13473,Q9BWS9,O43852,Q12846,Q6UXV4,P05067,O94919,P12814 14 +Adenylate cyclase inhibitory pathway 0.4631815626756687 0.2910360160014478 0.7710237743636583 1.0 0.912207766175879 3 P04899,P63096 2 +Sars cov infections 0.2994085696456195 0.2787492909429067 0.7804372324039006 1.0 0.9178420331956476 67 P05023,P78362,P21964,P27824,P61803,P46977,P04843,Q9H0U3,Q16706,Q10472,P48729,Q13724,P49354,P14314,Q99720 15 +Methionine salvage pathway 0.4422088363380641 0.262310202422666 0.7930822969514497 1.0 0.9260347322034792 5 Q13126 1 +Ion homeostasis 0.3582094596357754 0.2620733250989224 0.7932649117065482 1.0 0.9260347322034792 11 P16615 1 +Cardiac conduction 0.3582094596357754 0.2620733250989224 0.7932649117065482 1.0 0.9260347322034792 11 P16615 1 +Non integrin membrane ecm interactions 0.4020821609454262 0.2510978303227839 0.8017384733331789 1.0 0.9302010882057918 7 P11047,P23229,Q9Y296,P05556,P12814,O14936 6 +Rnd3 gtpase cycle 0.3235112822482708 0.247367719564244 0.8046236540633427 1.0 0.9327821014264696 20 P38159,Q14254,Q8TAA9,Q9NYL9,Q07065 5 +Josephin domain dubs 0.4451939291737012 0.2440573141384638 0.8071864313931043 1.0 0.9338303733890588 3 P54727,P55072 2 +Advanced glycosylation endproduct receptor signaling 0.3592167912002704 0.2343607759282967 0.8147049070074859 1.0 0.9354411867427864 9 P05067,P09429 2 +Transmission across chemical synapses 0.2966371592208643 0.2330799026679867 0.8156993605105756 1.0 0.9354411867427864 48 O75915,P21964,Q12959,P51812,Q9UBI6,Q9Y639,Q92796,Q96QD8 8 +Sema4d mediated inhibition of cell attachment and migration 0.3840966563641411 0.2272893713916176 0.8201987372537936 1.0 0.9377494874513008 2 P63000 1 +Free fatty acids regulate insulin secretion 0.4356379988757805 0.2208548690706033 0.8252054389287946 1.0 0.9389620399164542 3 P29992,O95573 2 +Thrombin signalling through proteinase activated receptors pars 0.4140925519814304 0.2119552577048724 0.8321419403890937 1.0 0.9437625862083536 6 Q9UBI6,P63218 2 +Rho gtpases activate ktn1 0.3846370287000691 0.1956506584361785 0.8448836067568559 1.0 0.9513362462046896 7 P63000,Q86UP2,P33176,Q9H0B6,P60953,Q07866 6 +Syndecan interactions 0.4164791901012501 0.192673239841627 0.8472148822560222 1.0 0.9532011264904408 5 P05556,P12814,P23229,Q9Y296 4 +Aquaporin mediated transport 0.4023313010142117 0.1797760221000655 0.8573284084957902 1.0 0.9607521530127426 6 Q9UBI6,Q99797 2 +Pi5p regulates tp53 acetylation 0.4180489176272186 0.1695778004244796 0.8653421823581555 1.0 0.9668579331049002 4 Q13526,Q8TBX8,P48426 3 +E2f enabled inhibition of pre replication complex formation 0.4060742407199124 0.1671430589080945 0.867257486417365 1.0 0.9680376053923474 5 P14635,O43913,P06493,Q9Y619 4 +Interactions of vpr with host cellular proteins 0.2814857665476992 0.1618380972283446 0.871433351239826 1.0 0.969632696572604 36 P05141,Q9BTX1,P12236,O15504,P12235,Q8TEM1 6 +Cdc6 association with the orc origin complex 0.4058459808881472 0.1567895023462198 0.8754107464383538 1.0 0.9732913180873668 3 O43913,Q9Y619 2 +Myogenesis 0.3685987619583636 0.1489554559242042 0.8815887817700798 1.0 0.9772502695005184 7 P19022,O60271,P60953,P35221,P35222,Q16539 6 +Met activates ptk2 signaling 0.4016301292861224 0.1487638533527757 0.8817399740394196 1.0 0.9772502695005184 3 P05556,P11047 2 +Pp2a mediated dephosphorylation of key metabolic factors 0.3985385047779708 0.1430444839500444 0.8862550492976808 1.0 0.981484023222216 3 P30153,P30154 2 +Laminin interactions 0.4017430418892378 0.1360072312623684 0.8918155643672245 1.0 0.9864327470884204 4 P05556,P11047,P23229 3 +G beta gamma signalling through cdc42 0.3986342234610538 0.1300420778694145 0.8965331359985791 1.0 0.9889881156484326 4 Q9UBI6 1 +Ca2 pathway 0.3788618031269008 0.121790093358301 0.9030652598977276 1.0 0.9946618740800576 6 Q9UBI6,P63218 2 +Collagen biosynthesis and modifying enzymes 0.3200801648813505 0.1125662454542469 0.9103744471387876 1.0 0.9980191920496646 11 P07237,O60568,P50454,O75718,Q32P28,P13674 6 +Activation of the ap 1 family of transcription factors 0.3707138842046152 0.0978815143612219 0.9220263788940636 1.0 1.0 3 Q16539,P27361 2 +Sumoylation of ubiquitinylation proteins 0.2810932211514239 0.0758830014575826 0.939512180734028 1.0 1.0 30 Q9BTX1,Q8N1F7,Q92621,P37198,A8CG34,O15504,Q7Z3B4,Q8TEM1,P12270 9 +Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.3568834987768094 0.0754433633193473 0.9398619585551802 1.0 1.0 6 P40939 1 +Transport of the slbp dependant mature mrna 0.2722128533426664 0.073457304468462 0.9414422183424778 1.0 1.0 34 Q9BTX1,Q8N1F7,Q92621,P37198,Q86V81,A8CG34,O15504,Q7Z3B4,Q8TEM1,P12270 10 +Sumoylation of sumoylation proteins 0.282024692588742 0.0716008920030915 0.9429195301835224 1.0 1.0 29 Q9BTX1,Q8N1F7,Q92621,P37198,A8CG34,O15504,Q7Z3B4,Q8TEM1,P12270 9 +Regulation of glucokinase by glucokinase regulatory protein 0.282024692588742 0.0716008920030915 0.9429195301835224 1.0 1.0 29 Q9BTX1,Q8N1F7,Q92621,P37198,A8CG34,O15504,Q7Z3B4,Q8TEM1,P12270 9 +Cd163 mediating an anti inflammatory response 0.2891261590334433 0.0670527281222422 0.9465397266437288 1.0 1.0 2 Q16539 1 +Aspartate and asparagine metabolism 0.3535016111674925 0.0632391488849046 0.9495760708493612 1.0 1.0 5 Q9UJS0 1 +Constitutive signaling by overexpressed erbb2 0.338487489457409 0.0419865169012629 0.9665094465934938 1.0 1.0 4 Q16543,P62993,P07900 3 +Interferon alpha beta signaling 0.2990856458100958 0.0396347017107652 0.9683843612012286 1.0 1.0 9 P10321 1 +Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 0.2788083192805026 0.0204594662327881 0.9836768465626772 1.0 1.0 3 P46087,P06748 2 +Rhob gtpase cycle 0.2751919924151962 0.0200997421180256 0.9839638058646027 1.0 1.0 28 P27105,Q8TAA9 2 +Ptk6 regulates rho gtpases ras gtpase and map kinases 0.3113048368953872 0.0102447680301959 0.9918260007440024 1.0 1.0 5 Q14185,P46108,P63000,P61586 4 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3297b39e5c37d17919cd0bf9787582efd42bec04 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Common pathway of fibrin clot formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective lfng causes scdo3", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of cell cycle genes", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose catabolism", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 processing", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of function of smad2 3 in cancer", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of activity of tfap2 ap 2 family transcription factors", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of tcf dependent signaling by dvl interacting proteins", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of fzd by ubiquitination", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of signaling by nodal", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retinoid cycle disease events", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 and foxp3 control the development of regulatory t lymphocytes tregs", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in bcr signaling", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of keratinocytes", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx1 regulates transcription of genes involved in interleukin signaling", "Runx1 regulates transcription of genes involved in wnt signaling", "Runx2 regulates bone development", "Runx2 regulates chondrocyte maturation", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates bcl2l11 bim transcription", "Runx3 regulates cdkn1a transcription", "Runx3 regulates immune response and cell migration", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sodium proton exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of immune response proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis of wybutosine at g37 of trna phe", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trail signaling", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns"], "available_proteins": ["AAAS", "AACS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APEH", "APEX1", "APIP", "APLP2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID4A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATG13", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATRIP", "ATRX", "AURKA", "AURKB", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1B", "BCAP31", "BCAS2", "BCAT2", "BCKDHA", "BCKDK", "BCR", "BCS1L", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BRAP", "BRCA1", "BRD1", "BRD2", "BRIP1", "BRPF3", "BSG", "BUB1B", "BUB3", "BUD31", "BYSL", "C16orf62", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC22", "CCDC59", "CCDC8", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKAL1", "CDKN2A", "CDS2", "CENPI", "CENPK", "CENPQ", "CEP250", "CEP290", "CEP97", "CERS1", "CERS2", "CERS5", "CETN2", "CFL1", "CGN", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHML", "CHMP1A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLINT1", "CLIP1", "CLNS1A", "CLP1", "CLSPN", "CLTA", "CLTB", "CLTC", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "COASY", "COG4", "COG5", "COG7", "COG8", "COLEC12", "COLGALT1", "COMMD2", "COMMD4", "COMMD7", "COMMD8", "COMMD9", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COTL1", "COX11", "COX14", "COX2", "COX4I1", "COX5A", "COX5B", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CRTAP", "CS", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTC", "CWC15", "CWC22", "CWC27", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEGS1", "DEK", "DENND4C", "DEPDC1B", "DERL1", "DERL2", "DFFA", "DFFB", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DSC3", "DSG2", "DSP", "DST", "DTX3L", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFHD2", "EFTUD2", "EHD1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "F11R", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM3C", "FAM49B", "FAM91A1", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXL18", "FBXO21", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1B", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTA", "FOXK1", "FPGS", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAN", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H1", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP3", "GTSE1", "GUSB", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS8", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKG", "ILF2", "ILK", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INCENP", "INPP4A", "INPPL1", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO5", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRS4", "ISCA2", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2B", "ITPA", "ITSN2", "IVD", "IWS1", "JMJD6", "JUP", "KANSL3", "KARS", "KAT7", "KCMF1", "KCTD15", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIN", "KLC1", "KLC2", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIG4", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRPPRC", "LRR1", "LRRC1", "LRRC41", "LRRC8A", "LRRC8C", "LRSAM1", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LZTFL1", "M6PR", "MACO1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MALT1", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED23", "MED24", "MED25", "MED27", "MEN1", "METAP1", "METAP2", "METTL1", "METTL3", "MFAP1", "MFN1", "MFN2", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIOS", "MIPEP", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVB12A", "MVD", "MVK", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1C", "MYO5A", "MYO6", "MYO9B", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEO1", "NF1", "NFRKB", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NLN", "NME1", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2C2AP", "NR2F1", "NR3C1", "NRBP1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT16", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OIP5", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLCD3", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLXNA1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPO", "POFUT1", "POGLUT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POM121C", "PON2", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPN1", "PTPN11", "PTPN13", "PTPN9", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RALA", "RALGAPB", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RELA", "REPS1", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMI1", "RNF123", "RNF14", "RNF2", "RNF20", "RNF40", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP36", "RRP7A", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SCAMP1", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SEL1L", "SENP1", "SENP3", "SEPT2", "SEPT7", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGSH", "SGTA", "SH3BP4", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SHPRH", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC38A2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A6", "SLIT2", "SLK", "SMAD4", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOD2", "SORBS3", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX18", "STX4", "STX5", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SULT1A4", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SV2A", "SYMPK", "SYNE1", "SYNE2", "TAB1", "TACC3", "TAF10", "TAF2", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D24", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TCEA1", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2", "TERF2IP", "TEX10", "TEX2", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "TGOLN2", "TGS1", "THADA", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THTPA", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM30A", "TMEM87A", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOLLIP", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPX2", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM56", "TRIO", "TRIP12", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TRMT61A", "TRMU", "TRRAP", "TSC2", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TSR3", "TSTA3", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE3D", "UBE4A", "UBQLN1", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USE1", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP32", "USP33", "USP34", "USP39", "USP47", 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complex iii assembly 6 10 2.0262943529851976 0.0427346296017252 3.3106796116504853 9.259708737864075 1.0287385637679851 0.2644162586394033 1.7668969355473032 1.3138647920792297 1.192785152283574 0.2813694304742245 0.0268439946301445 0.0021019285577768 0.0085055091795532 0.048077110185513 0.0005047578024907 +Progeriaassociated lipodystrophy 5 12 2.021932366555161 0.0431833394637526 2.5606796116504853 9.87135922330097 0.8348691672738174 0.3132697473637388 1.651332949166155 0.8732569863233294 1.0627007810416775 0.2700069969953336 0.0034090901495398 0.0798652174269664 0.0121688129697343 0.0082779259052177 0.0012775061284849 +Cholesterol biosynthesis with skeletal dysplasias 3 5 2.016902035943695 0.0437057375764344 2.703883495145631 6.024271844660194 1.6250539245333766 0.1427602110791373 1.3052115351448448 0.7101163612316155 0.9675759117714408 0.205892393525391 0.0001681812549661 0.0318339803833352 0.0017865936405575 0.0004307061505913 0.0001642346742964 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0 7 1.991895507052405 0.04638252404684 2.104368932038835 5.009708737864078 0.2024999555656973 0.6202249937394815 1.416367684355729 1.0702975326376547 0.7411287061140068 0.2899497341806522 0.3065127812497425 0.092554689717322 0.1803331870597798 0.396459747437317 0.6448862670706441 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4f1059b1c25678695e3d5b6581345af373b1d436 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 606, + "title": "Average number of proteins per term", + "value": 11.658415841584159 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ac73b99e984c448725ef15db7b69e58ba780f4d6 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..921a7ed90f0e56918ae466110181e6be8da8b9fa --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,108 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Electron transport chain oxphos system in mitochondria 0.6391288926681958 3.370115652540069 0.0007513664154363 0.3658686647389909 0.0137978196289226 51 P14406,P36542,O75964,P13073,P15954,P12235,O43674,O14949,P05141,P56134,O43676,Q9Y6M9,Q9UDW1,P14927,P21912,O95168,P51970,O75880,P56385,O96000,O75947,P03886,O75380,P24539,P00403,P22695,P12236,P06576 28 +Nonalcoholic fatty liver disease 0.5616530817466143 2.7587474366957054 0.005802335986089 0.9705910542154218 0.0719070273914814 53 P14406,P00403,P51970,O43676,P08574,Q9Y6M9,O96000,Q9P0J0,Q9UDW1,Q86Y39,O95168,P21912,P13073,O75380,P15954,O14949 16 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.658306325576997 2.758076182176345 0.0058142645910603 0.9708041101770574 0.0719070273914814 26 O95864,Q14534,Q15800,O00767,Q9BWD1,Q16850,Q14739,Q15392,O76062,P37268,Q9UBM7,P48449 12 +Sphingolipid metabolism overview 0.8578905194583816 2.696271256686163 0.0070120539196889 0.9859379115462912 0.0817173976025289 10 Q16739,Q9NRA0,P27544,Q96G23,Q13510,Q06136,O95470 7 +Sphingolipid metabolism integrated pathway 0.837980013882378 2.6884364826802947 0.0071787491638188 0.987298206355084 0.0817717261302819 11 Q8N5B7,Q16739,Q9NRA0,P27544,Q96G23,Q13510,Q06136,O15121,O95470 9 +Sphingolipid metabolism in senescence 0.799299084747263 2.6826518543522497 0.0073040983031056 0.988233840709612 0.0817717261302819 13 Q16739,P04062,Q96G23,P16278,Q13510,Q06136 6 +Sphingolipid pathway 0.8355837045297083 2.6773130217780707 0.0074215262989529 0.9890478218437856 0.0817717261302819 11 Q16739,P04062,Q9NRA0,Q13510,Q06136,O95470 6 +Eicosanoid synthesis 0.9435234616465262 2.6328965463607013 0.0084660130188898 0.9942135961507482 0.0884552394732282 2 P09960 1 +Mitochondrial complex i assembly model oxphos system 0.5908464648066118 2.556542234532017 0.0105718236644485 0.9984045988155 0.1085851718755222 31 Q96CU9,O43676,Q9Y6M9,O96000,Q9P0J0,Q8TB37,Q8N183,Q9BUB7,P03886,Q9NX14,O75380,O95168,Q9Y375,Q9NPL8,P51970 15 +Ferroptosis 0.6126266368077349 2.500567314141567 0.0123994566439618 0.999479668592776 0.1192709639085849 27 P09601,Q9Y277,P45880,P37268,Q9UKU0,Q96QD8 6 +Hematopoietic stem cell differentiation 0.9078392806968212 2.479249599502224 0.0131659137353961 0.9996749500636573 0.1227468265176929 2 P36896 1 +S1p receptor signal transduction 0.8159954226831949 2.429258412823595 0.0151297443544755 0.9999027953672404 0.1348327217472381 9 Q9NRA0 1 +Familial partial lipodystrophy fpld 0.8242131357137275 2.3140682961969827 0.0206639761508136 0.9999968038415636 0.1739217992693479 8 P20700,P49354,O75844,P02545,O60725 5 +Mitochondrial complex iv assembly 0.7571733580707399 2.3046871587658884 0.021184100589765 0.9999976835911544 0.173933025432073 11 P14406,Q9Y2R0,P13073,P15954,P00403 5 +Metabolism of spingolipids in er and golgi apparatus 0.950787401574796 2.2593121250522037 0.0238639762130048 0.9999995601887544 0.1807696198135117 5 Q06136,O95470,Q9NRA0,Q16739 4 +Nuclear receptors in lipid metabolism and toxicity 0.8536105647653747 2.241040885830309 0.0250234267400117 0.9999997859705968 0.1827011639090017 2 P08183 1 +Oxidation by cytochrome p450 0.9080910764750924 2.1855291868169098 0.0288500683400074 0.9999999802535936 0.1964397911690396 6 Q6UW02,Q16850,O43169 3 +Nephrotic syndrome 0.6990159609308266 2.1748813466412376 0.0296390090919649 0.9999999879330488 0.1995693278858972 13 O75844,Q9BT22,Q14108 3 +Oxidative phosphorylation 0.5350561864213165 2.139847179700953 0.0323671189529275 0.9999999978090408 0.2109083234997214 31 P56385,Q9Y6M9,O96000,Q86Y39,O75947,P03886,O75964,O75380,O95168,P24539,P51970 11 +Urea cycle and related diseases 0.8283225625175579 2.1280625123358603 0.0333319009427977 0.999999998802994 0.212628104620361 2 Q9UJS0 1 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.6518170717313618 2.1280518039909677 0.0333327886781094 0.99999999880366 0.212628104620361 16 P42167,P50402,P49354,O75844,P02545,O60725 6 +Irinotecan pathway 0.813711716774365 2.0622577797611807 0.0391832003416947 0.9999999999697868 0.2326744111554139 2 O15118 1 +Matrix metalloproteinases 0.8128687833661052 2.0584498476375974 0.0395469708729498 0.999999999975982 0.2326744111554139 2 P35613 1 +Vitamin d metabolism 0.9210230466554252 2.049802261347771 0.04038373085878 0.9999999999858372 0.2337131933102853 3 P04062,P38435 2 +Influence of laminopathies on wnt signaling 0.70528356912297 2.048665241821601 0.0404948602270296 0.9999999999867972 0.2337131933102853 11 P50402,P49354,O75844,P02545,O60725 5 +Mitochondrial complex iii assembly 0.7152911544577292 2.0262943529851976 0.0427346296017252 0.9999999999967968 0.2420297713892102 10 P08574,P22695,Q6DKK2,Q9UDW1,P14927,O14949 6 +Progeriaassociated lipodystrophy 0.68514228369208 2.021932366555161 0.0431833394637526 0.9999999999975888 0.2423065158799453 12 P20700,P49354,O75844,P02545,O60725 5 +Cholesterol biosynthesis with skeletal dysplasias 0.8891041382361937 2.016902035943695 0.0437057375764344 0.9999999999982684 0.2429878621221953 5 Q14739,Q16850,Q15392 3 +Acquired partial lipodystrophy barraquersimons syndrome 0.855736782902118 1.8833283771191096 0.0596558800416053 1.0 0.2876637549991759 5 O60725,P49354,P20700,P02545 4 +Cholesterol biosynthesis pathway 0.628487438203469 1.878860055828616 0.0602636042049991 1.0 0.2876637549991759 14 Q14534,Q15800,Q16850,P37268,Q9UBM7,P48449 6 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.8241711010219495 1.8458673079957093 0.0649114745515619 1.0 0.3002677150693563 6 P07099 1 +Vitamin d receptor pathway 0.6016077737318861 1.7811722930435927 0.0748843085039128 1.0 0.3312400799516143 15 Q92604,Q5VV42,P08183,Q96KA5 4 +Metapathway biotransformation phase i and ii 0.5197936508756822 1.7346298654796175 0.0828063860608798 1.0 0.346073585882022 24 Q8NCH0,P21964,P0DMN0,Q7LGA3,P07099,Q16850,Q6UW02 7 +Triacylglyceride synthesis 0.8390725048134181 1.7049584814637362 0.0882021680592601 1.0 0.3565073581128847 4 Q9HCL2,O00116 2 +Proteoglycan biosynthesis 0.8343303391001267 1.6860278229945656 0.0917904405060818 1.0 0.3565073581128847 4 Q8TB61 1 +Mitochondrial immune response to sarscov2 0.6588368948676926 1.6842671591228466 0.0921300492047021 1.0 0.3565073581128847 9 P35232,Q7Z434,Q9Y6M9,Q9Y276,Q99623,Q9Y375 6 +Endothelin pathways 0.6551667150040229 1.6661632443503 0.0956809045945767 1.0 0.3646706175114058 9 P16615,P00403 2 +Intracellular trafficking proteins involved in cmt neuropathy 0.5954508027148231 1.5475931208360494 0.1217202887039465 1.0 0.42142803425231 12 Q9NR77,Q8TB36,O95140 3 +7oxoc and 7betahc pathways 0.618756914101794 1.542873223531642 0.1228615387566485 1.0 0.42142803425231 10 O15118,Q9UBM7 2 +Thiamine metabolic pathways 0.7088297956552545 1.3624891595717004 0.1730435629719207 1.0 0.4763903815371713 6 Q9HC21,O14874 2 +Amyotrophic lateral sclerosis als 0.5840295442189617 1.310247576419269 0.1901120956727566 1.0 0.4947850807530323 9 P07197,Q9BUN8,P07196,O96008 4 +Envelope proteins and their potential roles in edmd physiopathology 0.4878191912699884 1.3098719780742976 0.1902391482103242 1.0 0.4947850807530323 19 P42167,P50402,Q14739,Q9BTV4 4 +Joubert syndrome 0.4694204994818861 1.2497304057818268 0.2113980462030398 1.0 0.5186526963523973 21 P41208,Q13432,O43924 3 +Tryptophan metabolism 0.5284342450105871 1.2417927811016112 0.2143130268896724 1.0 0.5197134138435963 13 P51648,Q15392 2 +Interactome of polycomb repressive complex 2 prc2 0.723271143817165 1.237825269895065 0.2157808564025307 1.0 0.5197134138435963 4 Q9Y2W1,Q9NYF8 2 +Nad biosynthetic pathways 0.6981364190657069 1.2346089882655893 0.2169760622152308 1.0 0.5197134138435963 5 Q8IXJ6 1 +Nad metabolism 0.7135510446748565 1.1984282084530098 0.2307503562440169 1.0 0.539855565453515 4 Q8IXJ6 1 +Glial cell differentiation 0.6144984546220786 1.1390380098484632 0.254687300990617 1.0 0.5653498329681828 2 P09543 1 +Statin inhibition of cholesterol production 0.6395562967397478 1.067551371015255 0.2857229293013104 1.0 0.5950106362769556 6 P37268,Q8WTV0,Q14534 3 +Sterol regulatory elementbinding proteins srebp signaling 0.3806450648765745 1.0526121975278513 0.2925187645399842 1.0 0.6029468411946615 35 Q9HCL2,Q9NR31,Q14534,O00767,Q16850,Q12770,P37268,Q8WTV0,P48449 9 +Ccl18 signaling pathway 0.5551563256052855 1.050163654182279 0.2936428768689545 1.0 0.603212147059615 8 Q86UE4,P00403 2 +Mitochondrial long chain fatty acid betaoxidation 0.4874715418120454 1.0088220244273416 0.3130599964596237 1.0 0.6113001399127671 13 P40939,O43772,P23786 3 +Acetylcholine synthesis 0.5802191626861393 0.9806711849585938 0.3267549179822693 1.0 0.6207319131575398 2 P35790 1 +Arrhythmogenic right ventricular cardiomyopathy 0.4815684775100923 0.9752382503009412 0.3294420926155001 1.0 0.6238809628906035 13 P50402,P16615,P02545 3 +Copper homeostasis 0.53718852744618 0.9630642647704354 0.3355152736957572 1.0 0.6305852696405542 8 O75880,O43819,P05067,P35670 4 +Lung fibrosis 0.6082043546651653 0.9348202918164398 0.3498809202960153 1.0 0.6356375807283101 6 Q8IZ81,P09601 2 +Fatty acid betaoxidation 0.4315152880134331 0.9331644330481818 0.3507350754126257 1.0 0.6356375807283101 19 P40939,Q9UKU0,O43772,P23786 4 +Glycerophospholipid biosynthetic pathway 0.5295223017187496 0.9260221724348418 0.3544344576509428 1.0 0.6356375807283101 8 Q9BTU6,Q9HCL2,Q86UL3,O00116,O14735,O95674 6 +Ciliopathies 0.4180547318676164 0.8916761493645667 0.3725665410188608 1.0 0.6506493482923045 21 O43924 1 +Kennedy pathway from sphingolipids 0.5951075221302612 0.8798150635151236 0.3789595029672239 1.0 0.6567636913858903 6 O95470 1 +Ovarian infertility 0.5552121382410733 0.8672102296993415 0.3858268322723199 1.0 0.6567636913858903 2 Q8WXH0 1 +Ketogenesis and ketolysis 0.6080101786728627 0.8619147132835794 0.3887344518211857 1.0 0.6567636913858903 5 O43772 1 +Striated muscle contraction pathway 0.590679750478206 0.8612999197570005 0.3890728798804201 1.0 0.6567636913858903 6 P08670 1 +Spinal cord injury 0.411013790980715 0.8425388799814908 0.3994863863306928 1.0 0.6614446724491798 21 P08670,Q9NQC3 2 +Vitamin a and carotenoid metabolism 0.6025894137506422 0.8399144912541435 0.4009563319380633 1.0 0.6620695835271564 5 Q8WTV0 1 +Mammary gland development pathway embryonic development stage 1 of 4 0.5436920483281747 0.8157916337858676 0.4146193190351832 1.0 0.6736174459391986 2 P23229 1 +Glycosaminoglycan degradation 0.5324800176687263 0.7701844128191399 0.4411905087024284 1.0 0.6926525041414868 7 P08236,P54802,P16278 3 +Primary focal segmental glomerulosclerosis fsgs 0.408592412384253 0.7367135573530997 0.4612965605072456 1.0 0.7094967121877594 18 Q14108 1 +Omega3 omega6 fatty acid synthesis 0.5592023453514373 0.7312356121398923 0.464635251442556 1.0 0.7100385000763981 6 O95864 1 +Thermogenesis 0.3598465984867898 0.7123212537635607 0.4762658657911234 1.0 0.7126348510356069 31 O43772,Q9UKU0,P51812 3 +Allograft rejection 0.4475140720126224 0.6944079569060905 0.4874264051552479 1.0 0.7231138329024884 11 P08670,P10321,P08183 3 +Camkk2 pathway 0.422344270330638 0.6886164659820072 0.4910646562841045 1.0 0.7231138329024884 14 P09601 1 +Oxysterols derived from cholesterol 0.4793874423400799 0.687423019597838 0.4918161956225904 1.0 0.7231138329024884 8 O14734,Q9UBM7,O14975,Q9Y305 4 +Arachidonate epoxygenase epoxide hydrolase 0.5119415566170165 0.6778585287386409 0.4978613968427972 1.0 0.728753638856848 2 P20674 1 +Omega9 fatty acid synthesis 0.5396928783871786 0.6524306912679602 0.5141233706471913 1.0 0.7382909066639761 6 O95864 1 +Male infertility 0.3744357567811678 0.6374082262431819 0.523858971424978 1.0 0.7471922241413864 23 Q15165 1 +Glycerolipids and glycerophospholipids 0.4672534295105666 0.6311824651562187 0.5279212258116868 1.0 0.7474097567107187 8 O14735,Q9HCL2,Q86UL3,Q9UG56 4 +Proximal tubule transport 0.4387280590976945 0.6133999342298391 0.5396119295304844 1.0 0.7474097567107187 10 P05023,P08183,P36543 3 +Ppar signaling pathway 0.3892503806828549 0.6127487316997752 0.5400424949471323 1.0 0.7474097567107187 18 O95864,O00767,Q9UKU0,P23786 4 +Inclusion body myositis 0.5576491763090601 0.5958006209738749 0.5513084288451733 1.0 0.7507051738673515 3 Q92542 1 +Regulation of apoptosis by parathyroid hormonerelated protein 0.4891285999441443 0.5830784176917748 0.5598405118564675 1.0 0.7522468961973822 7 Q9BXK5 1 +Degradation pathway of sphingolipids including diseases 0.4873693121023128 0.575698303615229 0.5648191221747896 1.0 0.7525394355914965 7 P17900,P16278 2 +Pkcgamma calcium signaling pathway in ataxia 0.551995503091631 0.5753930789968709 0.5650254838186979 1.0 0.7525394355914965 3 P23634,P29992 2 +Congenital generalized lipodystrophy cgl 0.4852486653554275 0.5675634198104917 0.5703314517661684 1.0 0.7529866225932419 2 P62993 1 +Hair follicle development organogenesis part 2 of 3 0.5427206295671794 0.5423944497717508 0.5875468023451607 1.0 0.7625609264542846 3 P05556,Q9BZE4 2 +Adipogenesis 0.3826272496342412 0.5385943461515474 0.5901667896156098 1.0 0.7625609264542846 17 P43490,O75844,P02545 3 +Il18 signaling pathway 0.3255884815792562 0.5299025383218285 0.596179506170702 1.0 0.7654338574988251 61 P09601,Q9NZJ7,Q9UMR5,P35613,Q8TCT8,Q9HC07,Q9Y6M7,Q13011,P40939 9 +Alzheimers disease and mirna effects 0.3006666259125247 0.5249336799934589 0.5996292951887052 1.0 0.767182020171261 89 Q92542,O95197,P16615,Q9Y277,P21796,Q9NQC3,P45880,P12236,P49721,P12235,Q96IX5 11 +Alzheimers disease 0.2907705672887414 0.3930035792272877 0.6943168378159186 1.0 0.8283731403255586 88 Q92542,O95197,P16615,Q9Y277,P21796,Q9NQC3,P45880,P12236,P49721,P12235 10 +Gastric cancer network 2 0.3514122557273978 0.3543222726470923 0.7230973779148582 1.0 0.8475764236294082 17 Q86UE4,Q14739 2 +Riboflavin and coq disorders 0.4586700690447949 0.3506269943726037 0.7258682021343541 1.0 0.8483120967159427 6 Q16134 1 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.3678825182222543 0.3277601923741639 0.7430929879875996 1.0 0.8607655759042391 12 P07237,Q96AY3,P50454,Q32P28,Q5JRA6,P13674 6 +Purinergic signaling 0.4634420697412923 0.3261744830589 0.7442923461614213 1.0 0.8607655759042391 5 P04899,P09471,P63096,Q96RD7 4 +Serotonin htr1 group and fos pathway 0.3713400900900887 0.2820638643830982 0.7778945407126601 1.0 0.8811291433119103 9 P04899,Q02750,P61586,P09471,P27361,P63096,P08754,Q16539 8 +Inflammatory response pathway 0.4015172801348732 0.2746838246212529 0.7835591593978659 1.0 0.8842399452422844 2 P11047 1 +Folate metabolism 0.3362367218685212 0.2530085893674338 0.8002615757451941 1.0 0.8947952432402154 16 P41440,Q8WTV0,P00374 3 +Vitamin b12 disorders 0.423671633398934 0.1820317477222177 0.8555578110327902 1.0 0.9163226872869794 4 Q9NPF0,P22033,Q99707 3 +Sarscov2 b117 variant antagonises innate immune activation 0.344478786175895 0.1403884636173216 0.8883530722852906 1.0 0.9477851440226868 2 Q7Z434 1 +Cytoplasmic ribosomal proteins 0.280937697467414 0.1356811866468111 0.8920733210495051 1.0 0.9481816916478876 76 Q02878,P39023,P27635,P61927,P84098,P18124,P62266,P46779,P62424,P49406,P46776,P47914,P40429,P61513,P46778,P62917,Q07020,P61313,P83881,P36578,Q9Y3U8,Q02543,P18077,P51812,P62847,P62854 26 +Angiopoietinlike protein 8 regulatory pathway 0.2868457505416456 0.1155355261481773 0.9080206632106608 1.0 0.954094314333379 30 P41440,O75955,P51812,Q9UPT5,O00767 5 +Transcription factor regulation in adipogenesis 0.3189098061253185 0.0999190464442174 0.9204085951464048 1.0 0.9567197404094706 2 P04150 1 +Mapk cascade 0.3709223847019128 0.0929319704949545 0.9259576068605956 1.0 0.9598859105835316 5 Q16539,Q02750,P62993,P27361 4 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.3624137529738959 0.0865781128259136 0.93100686399512 1.0 0.9598859105835316 3 P08195 1 +Serotonin receptor 467 and nr3c signaling 0.3708181051447877 0.0829256161302258 0.9339106854604418 1.0 0.9598859105835316 4 Q02750,P27361,P04150 3 +Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence 0.2917668850217966 0.0427975425595746 0.9658629229497953 1.0 0.9853753052316092 15 Q8IXJ6 1 +Mecp2 and associated rett syndrome 0.282666206436835 0.0261360977736507 0.979148785029349 1.0 0.997250695340816 20 P52597,P49711,P35637,P67809,Q03518,P31943 6 +Ethanol effects on histone modifications 0.2854679822963372 0.00545878922776 0.995644537985456 1.0 1.0 11 P00374 1 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..42027659c97c200e6d9d100ef0c11865b54b3fb9 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Activation of nlrp3 inflammasome by sarscov2", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoe and mir146 in inflammation and atherosclerosis", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Bone morphogenic protein bmp signaling and regulation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna for targeting cancer growth and vascularization in glioblastoma", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCD3", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APEX1", "APIP", "APLP2", "APMAP", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID4A", "ARIH2", "ARL2", "ARL3", "ARL8B", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG13", "ATG3", "ATG5", "ATG7", "ATIC", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AURKA", "AURKB", "B3GALT6", "BAG2", "BAG3", "BAG4", "BAIAP2", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BCAS3", "BCAT2", "BCKDHA", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BLM", "BLVRA", "BPTF", "BRAP", "BRCA1", "BRD1", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "C1QBP", "C21orf59", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZB", "CARM1", "CASK", "CASP2", "CASP8", "CBFB", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA7L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CDKN2A", "CDS2", "CEBPZ", "CELF1", "CELF2", "CEP170", "CEP250", "CEP290", "CEP350", "CEP44", "CEP97", "CERS1", "CERS2", "CERS5", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHKA", "CHMP5", "CHMP6", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHUK", "CIP2A", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLIP1", "CLK3", "CLP1", "CLPTM1L", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT10", "CNOT9", "CNP", "COA3", "COASY", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "COX11", "COX14", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DARS", "DBNL", "DCAF1", "DCAF7", "DCK", "DCP1A", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDAH2", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEGS1", "DEK", "DERL1", "DFFA", "DFFB", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLG1", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC3", "DSG2", "DSP", "DSTN", "DTX3L", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERI1", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC2", "EXOSC7", "EXOSC9", "EZR", "F11R", "FADS2", "FAF1", "FAH", "FAM120A", "FAM91A1", "FANCA", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXRED1", "FPGS", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GAL", "GALNT1", "GAPDH", "GART", "GBA", "GBE1", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GID8", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPS1", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2H1", "GTF2H4", "GTF2I", "GTPBP4", "GTSE1", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUS1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKG", "ILF2", "ILK", "IMP3", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INPPL1", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITCH", "ITGA6", "ITGB1", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIF15", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KLC1", "KLC2", "KPNA1", "KPNA4", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LEO1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIN28B", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM2", "LSS", "LTA4H", "LUZP1", "LZTFL1", "MACF1", "MAD2L1", "MAEA", "MAGED1", "MAGT1", "MALT1", "MANF", "MAP1B", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED14", "MEPCE", "METTL3", "MFAP1", "MFN2", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MKLN1", "MMAB", "MOCS1", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVB12A", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO5A", "MYO6", "MYO9B", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCAPH2", "NCBP1", "NCBP2", "NCDN", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEO1", "NF1", "NFATC2IP", "NFRKB", "NIPBL", "NKRF", "NME1", "NME3", "NONO", "NOP2", "NOTCH2", "NPC1", "NPC2", "NR2F1", "NR3C1", "NRP1", "NSD1", "NSDHL", "NSF", "NT5C3A", "NTHL1", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "ORC5", "OTUD7B", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PANX1", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PEBP1", "PECR", "PELO", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PISD", "PKM", "PKN1", "PKN2", "PLCD3", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLXNA1", "PMPCA", "PMVK", "PNKP", "PNP", "PNPO", "PNPT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCZ", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN9", "PTPRF", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB13", "RAB14", "RAB21", "RAB23", "RAB2A", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RB1", "RBBP7", "RBL1", "RBM14", "RBM17", "RBM39", "RBM4", "RBM47", "RBM5", "RBMX", "RBPJ", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RELA", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RIF1", "RIPK1", "RMI1", "RMND5A", "RNASEH2A", "RNF14", "RNF2", "RNF20", "RNF40", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RRAS2", "RRBP1", "RRM1", "RRM2", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SASS6", "SCAF11", "SCAMP2", "SCAP", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC13", "SEC14L2", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SEPT11", "SEPT8", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SEZ6L2", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SGSH", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A25", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC38A2", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLIT2", "SMAD4", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNIP1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOD2", "SORT1", "SPEN", "SPHK2", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSNA1", "SSR3", "SSR4", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX4", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT1A4", "SUN1", "SUPT5H", "SUZ12", "SYNE1", "SYNE2", "TAB1", "TALDO1", "TAP1", "TARDBP", "TBC1D10A", "TBC1D4", "TBCA", "TBL1XR1", "TBL2", "TCF20", "TCP1", "TDP2", "TECR", "TEDC1", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TLN1", "TM7SF2", "TMED10", "TMEM165", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOLLIP", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIO", "TRIP13", "TRIP4", "TRMT2A", "TRRAP", "TSC2", "TSC22D3", "TSG101", "TSPO", "TSPYL1", "TTC19", "TTF2", "TTI1", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWISTNB", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2G2", "UBE2L3", "UBE2T", "UBE3A", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNG", "UPF1", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP32", "USP5", "USP7", "USP8", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS11", "VPS16", "VPS18", "VPS28", "VPS33A", "VPS37B", "VPS4A", "WAPL", "WARS", "WASF2", "WASL", "WDHD1", "WDR1", "WDR26", "WDR48", "WDR5", "WFS1", "WIPI2", "WNK1", "WRN", "XAB2", "XIAP", "XPNPEP3", "XPO1", "XPO5", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YES1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ABCB1", "ACAT2", "ACOT8", "ACOT9", "ACSL6", "ACVR1B", "AGPS", "ALDH3A2", "ALG1", "APP", "ASAH1", "ATP1A1", "ATP2A2", "ATP2B4", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP6V1E1", "ATP7B", "BCKDK", "BCL2L13", "BCLAF1", "BCS1L", "BSG", "CD320", "CDIPT", "CDKAL1", "CDS2", "CERS1", "CERS2", "CERS5", "CETN2", "CHKA", "CHST14", "CLPTM1L", "CNP", "COA3", "COMT", "COX2", "COX4I1", "COX5A", "COX7A2", "COX7C", "CPT2", "CTCF", "CYB5B", "CYC1", "CYP20A1", "CYP51A1", "DEGS1", "DERL1", "DHCR24", "DHCR7", "DHFR", "ECH1", "ELMOD2", "EMD", "EPHX1", "ETFDH", "EXOC7", "FADS2", "FDFT1", "FKBP10", "FLOT1", "FNTA", "FOXRED1", "FUS", "GBA", "GDAP1", "GGCX", "GLB1", "GM2A", "GNA11", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GPAM", "GPAT4", "GRB2", "GTPBP4", "GUSB", "HADHA", "HLA-C", "HMOX1", "HNRNPF", "HNRNPH1", "HS2ST1", "ICMT", "ITGA6", "ITGB1", "KDSR", "LAMC1", "LBR", "LMNA", "LMNB1", "LPGAT1", "LSS", "LTA4H", "MAP2K1", "MAPK14", "MAPK3", "MAVS", "MFN2", "MIA3", "MRPL19", "MSMO1", "MTCH1", "MTDH", "MTR", "MUT", "NAGLU", "NAMPT", "NCSTN", "ND1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF1", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS6", "NEFL", "NEFM", "NPC1", "NR3C1", "NUBPL", "P3H1", "P4HA1", "P4HB", "PANX1", "PDE6D", "PHB", "PHB2", "PI4K2A", "PISD", "PON2", "PPT2", "PSMB2", "PXMP2", "RHOA", "RPL10", "RPL13A", "RPL15", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL8", "RPS23", "RPS24", "RPS26", "RPS6KA3", "RTN3", "RTN4", "SAR1A", "SCAP", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SDHB", "SERPINH1", "SGPL1", "SIRT2", "SLC19A1", "SLC25A13", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC35B2", "SLC38A2", "SLC3A2", "SLC4A7", "SPHK2", "SPPL2A", "SQLE", "SULT1A4", "SYNE2", "TAP1", "THRAP3", "TIMMDC1", "TM7SF2", "TMEM165", "TMEM43", "TMEM70", "TMPO", "TOMM40", "TTC19", "UGCG", "UNC119", "UQCR10", "UQCRB", "UQCRC2", "UQCRQ", "USMG5", "VDAC1", "VDAC2", "VDAC3", "VIM", "YBX1", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..aeba0f1c7f655d3c93fe4564accd0f742083f1af --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "er", "1": "mitochondria", "2": "vesicles"} 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b/opencell_localization/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +er 46 93 4.4397776598723535 9.005186395905085e-06 29.17233009708738 87.61893203883496 1.3358083950399515 0.3757472714196316 13.465054065187209 8.223393744963309 2.0429537263872786 0.4010648005920765 2.5744978729057643e-09 0.0274566338315537 0.000371914625626 2.0081373339155805e-12 1.2149711754919331e-19 +mitochondria 8 11 2.316124346107373 0.0205514803574164 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 0.0203954716413504 0.0015706319822673 0.0063961411835862 0.0031665778749487 0.0002343739811342 +vesicles 64 183 2.2009063876080823 0.0277426516467143 42.101941747572816 169.6626213592233 0.6789633151163722 0.6006686966705359 14.133870910307197 18.74575061031192 1.1351302778834993 0.3922666308151308 0.0067587538090797 0.8024142775168469 0.2249958481130711 0.0014471219904768 2.2037417807001465e-05 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c09a8f6a6ff21fb2be2aead9c085898b01ace115 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 103.41176470588235 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bfc02b3e95e852b0f88ea95d0765f1e798f24883 --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bb148f7a091959805fb693029a8e9361f8734826 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +er 0.6428317736177075 4.4397776598723535 9.005186395905085e-06 0.000153077140527 0.0001530881687304 93 Q9P0I2,Q15041,Q9NPA0,Q00765,Q9Y5M8,Q9NR31,Q8N4V1,O60499,Q969Q5,Q16850,Q06136,Q5J8M3,P48449,Q8N766,O75915,O96005,P27824,P04843,P49755,Q15392,Q07065,O15121,Q96A33,Q8NHH9,Q8NF37,Q8N5B7,O00264,P51572,Q969V3,O00767,Q9P2W9,O14735,Q15363,Q9UM00,Q9NTJ5,P46977,Q12981,Q9NQC3,Q9Y3E0,Q9UKR5,O15173,Q14739,O15269,Q86Y07,Q96N66,O95470 46 +mitochondria 0.7595277800348911 2.316124346107373 0.0205514803574164 0.2974334949223584 0.0786041796656905 11 Q9NR31,Q15388,Q9Y277,P21796,O95140,Q969Q5,P45880,Q9NVH1 8 +vesicles 0.3863785776045682 2.2009063876080823 0.0277426516467143 0.38015802597621 0.0786041796656905 183 Q8NBN3,Q8N6T3,Q15758,Q10713,Q86UL3,O60499,P13473,O15126,Q9UNK0,Q93050,Q9H2J7,Q9H0A8,P61026,P56589,Q06136,Q969M3,P48449,P04439,Q9P253,P21281,O96005,P11279,P61019,P49257,Q9NVJ2,Q8IXU6,P49755,P53367,Q9NPI6,Q15738,Q15392,Q9H6H4,Q86Y82,O15121,P30825,Q8NF37,P51798,Q9BTU6,Q9UEU0,Q6PHR2,O15127,Q8N0T1,Q5VW38,O00264,Q969V3,O15400,Q9H9H4,O00767,O14735,Q15363,Q8IZA0,Q9UM00,P53985,P05023,P41440,O43808,Q9Y3E0,Q9UKR5,O15173,P20020,O15258,O60826,O15269,O95470 64 +golgi 0.3541193564049812 0.8542318401396569 0.392976544522662 0.9997937029421384 0.5558079516445007 64 Q8NBN3,Q8N6T3,Q9NR31,O15126,Q9Y487,P61026,Q969M3,P61019,P36543,Q9H8Y8,Q8IXU6,P49755,P53365,P53367,Q9Y6B6,Q14677,O15127,Q5VW38,O14735,Q8IZA0,Q9UM00,Q9P0L0,Q9NTJ5,Q9Y3E0,O15258 25 +nuclear_membrane 0.2985364711357436 0.2563040031201608 0.7977161064305436 0.9999999999984102 0.7977161064305436 33 P42167,Q5JTV8,Q14739,P02545 4 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..533841ad22300cd5914394cf4257a283694e32ad --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACAP2", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT1S1", "AKT2", "ALDH9A1", "ALG2", "ANAPC16", "ANAPC2", "ANAPC4", "ANXA11", "AP2B1", "AP2S1", "APLP2", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGEF7", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARPC2", "ARPC3", "ATG13", "ATG3", "ATG4B", "ATG7", "ATL2", "ATP1A1", "ATP2B1", "ATP6AP1", 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0.3470065139863294 0.0012495303223863 0.0009284037639392 0.0002635726510143 0.0004098971943574 1.0368990150422038e-05 +membrane trafficking regulatory protein 6 23 2.828672230220384 0.00467415430848 4.949029126213592 18.78640776699029 1.0645815505395402 0.2320552342124929 2.3097144002673033 2.893415643517755 1.4460865220385617 0.2677048300346334 0.0130214348748247 0.001829927485586 0.0134897524236001 0.0082073559004823 0.0128679597964932 +mitochondrial carrier protein 6 9 2.7802727941267538 0.0054313251724398 3.2936893203883497 7.065533980582524 1.4583792806536486 0.1840967072966826 2.0141872967986307 1.116111686789906 1.1161599809390137 0.2507152229846449 6.3744357536624e-10 1.0 0.0063961411835862 5.915471813879599e-09 2.7973786968355555e-08 +acyltransferase 7 16 2.54761448670454 0.0108462257280144 5.550970873786408 17.609223300970875 0.8395368249042097 0.3495065414698917 3.0409541216574527 2.8086572783837886 1.152491475155923 0.3107783941454108 0.0355040413058726 0.0159273139692264 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0.16461969248918 0.4737165174911525 0.3475241094728322 0.5828259131590167 0.373665486418114 0.6514285536848076 +oxidase 5 14 2.041304967632529 0.0412205236157929 5.111650485436893 13.890776699029129 1.1786899361665428 0.2351652471103072 2.6295852591466065 1.831549924215542 1.2715889014379809 0.2754701040210626 0.0188740973653811 0.1416218084112404 0.2685126379615966 0.0427102581002517 0.0717785358518721 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0be02a5a02973fe0e1eefea7d7b2aa0c2f9b0358 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 164, + "title": "Average number of proteins per term", + "value": 14.579268292682928 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0ec394f9d08f82c567363359dce7e37726b44e6d --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..324c17fe347542d410e283b6dfc1c0a0c938764c --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,49 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +oxidoreductase 0.6016120788941516 3.0115148287636337 0.0025994770582036 0.3474511630613602 0.0327934028881072 46 P00403,P51970,O43169,O43676,Q9Y6M9,O96000,Q16134,Q9Y320,Q86Y39,Q8N0U8,Q8N4Q0,O75380,O95168,P16435,O15254,O14949 16 +membrane trafficking regulatory protein 0.6946806155690483 2.828672230220384 0.00467415430848 0.5362262352780169 0.0404880603763696 23 Q9P253,P24390,Q14108,P13473,O43760,Q8WTV0 6 +mitochondrial carrier protein 0.8949287879816213 2.7802727941267538 0.0054313251724398 0.5906419446080086 0.0404880603763696 9 Q9NZJ7,Q9HC21,Q86VD7,Q70HW3,Q9BSK2,Q9Y6C9 6 +acyltransferase 0.7276393265637466 2.5476144867045396 0.0108462257280144 0.8327888467138347 0.0741158758080985 16 Q8NF37,Q9HCL2,Q9NUQ2,Q8NCC3,Q92604,P49354,P23786 7 +glycosyltransferase 0.6428573424114232 2.3911225271775765 0.0167969462192592 0.9378433099352632 0.1020258955540188 21 Q8N4A0,P61803,Q16739,P46977,Q8N6G5,Q86SF2,P04843,Q8NBN7,Q9H0U3,Q8TCJ2,Q10472,Q9BT22 12 +secondary carrier transporter 0.6844944273471835 2.3114522344988844 0.0208078886056506 0.9682066281279692 0.1100804429460227 16 O75746,Q8TB61,P04920,Q8WWI5,Q9Y6M7,Q9UBX3,O95202,Q02978,Q9UJS0,Q92581 10 +serine protease 0.663446485044965 2.193773230132546 0.0282517162369722 0.9909046316046218 0.1309729363239446 16 Q9H3G5,O14773,Q16740,P67812,P42785,Q9HB40 6 +oxygenase 0.8512937778429562 2.1861063890563655 0.0288078226766748 0.9917196479306212 0.1309729363239446 7 Q6UW02,P09601,P30519,Q16850 4 +voltage-gated ion channel 0.9435075885328844 2.1380409808045515 0.0325134173136278 0.9955764398380432 0.1333499418421 3 P45880,P21796 2 +transfer/carrier protein 0.698757543206308 2.0919409466103107 0.0364437986255827 0.9977309903779676 0.1404423423804577 12 P05141,Q9Y5M8,O15127,O15126,P12236,P17900,P12235,O14828 8 +calmodulin-related 0.6665066589885296 2.0877178124973907 0.036823297087559 0.9978729436935948 0.1404423423804577 14 Q9BRK5,P80303,P41208,Q14257,Q02818 5 +transmembrane signal receptor 0.8174095412456437 2.04195055180139 0.0411564365640382 0.9989846116219856 0.1469601276736967 7 O15173,Q99720,O00264 3 +oxidase 0.6579820919394844 2.041304967632529 0.0412205236157929 0.9989956812987864 0.1469601276736967 14 O75880,P14406,Q15800,P13073,P15954 5 +reductase 0.4959058460733569 1.9397491294123013 0.0524101856882641 0.9998535319339964 0.1719054090575064 33 O95881,Q9H7Z7,Q9UDW1,Q14739,Q15392,Q06136,P00374,O76062 8 +G-protein coupled receptor 0.8903570424514979 1.9080163242865469 0.0563891064307542 0.9999265413165244 0.1751443027754327 4 Q8NBN3,Q9NPR9,Q5VW38 3 +transporter 0.4583617166853296 1.906537857708944 0.0565804588146499 0.9999289444038342 0.1751443027754327 61 P41440,Q9NR77,O60830,Q92544,P53007,Q99595,O43772,O43615,O43681,Q567V2,Q9H2D1,Q9HD45,Q15070,Q99805,Q8TEM1 15 +lipase 0.8827993254637456 1.898202090519387 0.0576694655480083 0.9999412056937336 0.1751443027754327 3 Q9Y3E0,Q9H6V9 2 +amino acid transporter 0.824790733312766 1.7580227624602676 0.0787436363589746 0.9999985598685638 0.2203701636747337 5 Q96QD8,O14925,P30825 3 +SNARE protein 0.6204026634454406 1.754881903878806 0.0792795101024956 0.9999986909370416 0.2203701636747337 13 Q9UEU0,O60499,O15400,Q9P2W9,Q12846,Q5SQN1,Q86Y82 7 +protein modifying enzyme 0.4971577428368773 1.6372650528800532 0.1015750996428539 0.9999999765030256 0.2686825216359362 26 Q9UMR5,P51812,P50897,Q86YN1,O60725 5 +ATP-binding cassette (ABC) transporter 0.6346929738130567 1.6241877492563384 0.1043357446559254 0.9999999858153126 0.2716041606916154 10 P28288,O14678,Q03518,P08183,Q03519 5 +primary active transporter 0.4783993114542892 1.6081210443249654 0.1078086710567729 0.9999999924991292 0.2762597195829807 29 P05023,Q9GZP9,Q6NTF9,Q9NS69,P16615,O75381,Q8N4H5,Q9Y5J6,P35670,O96008,Q96NB2,Q9BUN8,Q6P4A7 13 +ATP synthase 0.5181424114735408 1.5447520105396355 0.1224062591311916 0.9999999994986548 0.2952150955516974 20 P56385,P56134,P36542,Q93050,O75947,Q9Y487,O75964,P06576,Q96IX5,P24539 10 +major histocompatibility complex protein 0.7756536407084518 1.450076305071161 0.1470372418778374 0.9999999999952952 0.3373009355808581 4 P55899,P10321,P01889 3 +metalloprotease 0.4620307807302792 1.4419947227163348 0.149303862369533 0.999999999996959 0.3373009355808581 28 Q99797,Q10713,P53582,P42892,P22695,O75844,Q9NZ08,Q7Z2K6,P55786,P14735,Q96TA2 11 +esterase 0.6353036223442214 1.4387025009706025 0.1502348304480112 0.9999999999974588 0.3373009355808581 8 Q8IY17,Q9H0P0,Q9NUJ1,Q9Y305,Q969T7 5 +cytoskeletal protein 0.661328203967577 1.3518133662537226 0.1764350271593087 0.999999999999985 0.3757836942094367 7 Q16181,Q15019,Q14141,Q9NVA2,P27105 5 +kinase 0.4635013566308015 1.2840189224005367 0.1991353346288937 1.0 0.4133948718878301 23 Q9BTU6,Q9BRR6,Q13232,Q8WVC6,Q9NRA0,P52789 6 +heterotrimeric G-protein 0.5745478395356499 1.2622446550551494 0.2068607648384368 1.0 0.41805689871852 9 Q9UBI6,Q8NHH9,P09471,P63218 4 +glucosidase 0.7160471999080289 1.220106124471194 0.2224246471651385 1.0 0.4291487310009731 3 P10253 1 +ribosomal protein 0.3390216459186267 1.18124755509065 0.2375043946869335 1.0 0.4456424798414782 124 Q96GC5,Q02878,P39023,P27635,P61927,Q96A35,Q9NWU5,P84098,P18124,Q9BYD1,P62266,P62910,P46779,P50914,Q9BRJ2,P62424,P82933,Q9BYD2,P82663,P46776,P49406,P47914,P40429,Q13084,P46778,O76021,P62917,Q9Y3B7,Q5T653,P82650,P82930,Q07020,P61313,P83881,Q9Y2R9,P36578,Q9HD33,Q7Z7H8,Q9BYN8,Q9Y3U8,P82912,P62241,P18077,Q92665,Q02543,Q9Y3D9,P62847,P62854 48 +C2H2 zinc finger transcription factor 0.7008370816727671 1.146951599182522 0.2514016252492159 1.0 0.4599477247078351 4 P49711 1 +transferase 0.401628203807648 1.1445144789046404 0.2524103367299095 1.0 0.4599477247078351 33 Q8NCH0,Q2TAA5,O43505,P0DMN0,Q7LGA3,Q99735,P43490,O14735,P37268 9 +phospholipase 0.5978380632038642 1.063569156722044 0.2875239209308899 1.0 0.4939246415508361 7 Q8N2A8,Q8IV08 2 +aspartic protease 0.65264786750319 0.9623345411654808 0.3358815834925104 1.0 0.5453918781462546 3 Q8TCT8 1 +integrin 0.5436920483281747 0.8157916337858676 0.4146193190351832 1.0 0.6142321907112869 2 P23229 1 +homeodomain transcription factor 0.5288002247822311 0.7503285046918021 0.4530568790096221 1.0 0.6460985057180698 2 Q13330 1 +tight junction 0.5186850238831051 0.7066163875747943 0.4798049022313526 1.0 0.6644761578348749 2 Q07157 1 +translational protein 0.5096937341949869 0.6683458249534896 0.5039128683134197 1.0 0.6721638275931632 2 P54577 1 +cadherin 0.5609341717729915 0.6077545778620981 0.5433502590051087 1.0 0.7128755398147026 3 Q14574 1 +dehydratase 0.5514333895446946 0.5733758734032929 0.566390222481731 1.0 0.7314015471417629 3 Q15738,P61457 2 +Hsp90 family chaperone 0.5316277762159005 0.4961936931815068 0.6197577602536575 1.0 0.7585094976238793 4 P07900,P08238,Q12931 3 +lyase 0.3578122943732957 0.3505786885934587 0.7259044470341305 1.0 0.8325057993957861 15 O95900,P22830,Q9UHG3 3 +ion channel 0.4449001485806234 0.30519471917752 0.7602178541581806 1.0 0.8598326074616662 6 P51790,Q9C0H2,Q96S66 3 +nucleic acid metabolism protein 0.4252670980302871 0.2443381920821334 0.8069689066547203 1.0 0.9002918414379193 6 P49750,Q8IWR0,Q9Y2W1,Q9NYF8 4 +membrane traffic protein 0.2812079073062818 0.1170044582998241 0.9068565205383856 1.0 0.9720553553483348 73 Q00765,Q9H223,P40855,Q13432,P43307,P49257,P51572,Q9UBC2,O60313,A6NIH7,Q9NX40,Q96RL7,Q96PC5 13 +kinase modulator 0.3751406074240823 0.1008317508289254 0.919684021762049 1.0 0.9794037634349094 5 Q99570,P10644,P67870,P54619 4 +chaperone 0.2686289884381951 0.0076661957186666 0.9938833207094828 1.0 1.0 77 P07237,Q9Y2R0,P27824,P30533,Q9NWM8,Q9Y680,O15260,Q9NVH1,O14656,Q8N183,Q96I36,Q9Y3C6,P46379,Q5TC12,Q96KC8,O14967 16 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9befe7d5bf16af2f935ca0fe0356a1828fc0de57 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "C4 zinc finger nuclear receptor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "amylase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic helix-loop-helix transcription factor", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "serine/threonine protein kinase receptor", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP10", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANKHD1", "ANLN", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APIP", "APLP2", "APOL2", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGDIA", "ARHGEF1", "ARHGEF7", "ARID3B", "ARID4A", "ARIH1", "ARIH2", "ARL1", "ARL6IP5", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATG3", "ATG4B", "ATG5", "ATG7", "ATL2", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCAT2", "BCKDHA", "BCKDK", "BCLAF1", "BCR", "BDH2", "BET1", "BLM", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD1", "BRIP1", "BRIX1", "BRPF3", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CACTIN", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD320", "CD47", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2AIP", "CDS2", "CEBPZ", "CEP170", "CEP250", "CEP350", "CEP97", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHML", "CHMP1A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLIP1", "CLK3", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COA3", "COASY", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSGALNACT2", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC22", "CWC27", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCAKD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDT", "DEGS1", "DEK", "DENR", "DEPDC1B", "DERL1", "DERL2", "DFFB", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DRAP1", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "ENY2", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAHD2A", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FOXRED1", "FPGS", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAN", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GID8", "GINS2", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP3", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGCR", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B7", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUS1", "HUWE1", "IARS", "IARS2", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "ISG20L2", "ISOC1", "ISOC2", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITPA", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCMF1", "KCTD10", "KCTD12", "KCTD15", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KLC1", "KLC2", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LENG8", "LEO1", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIG4", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRR1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTN1", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MACO1", "MAGED1", "MAGED2", "MAGT1", "MALT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED17", "MED23", "MED24", "MED25", "MED27", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL7B", "MFAP1", "MFSD5", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MKRN2", "MLLT1", "MMAB", "MMS19", "MOCS3", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKIPSD", "NCOA5", "ND1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NENF", "NF1", "NFRKB", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NPEPPS", "NPM1", "NPTN", "NR2F1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN3", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPN1", "PACSIN2", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PARG", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF3", "PHF6", "PHGDH", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIK3C2A", "PIK3R4", "PIN1", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCD3", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POM121C", "POP7", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN9", "PTPRF", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP6", "RBL1", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBM47", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "RELA", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIOK2", "RIPK1", "RNASEH2A", "RNF14", "RNF2", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SACM1L", "SAE1", "SAMD1", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGSH", "SHMT1", "SHMT2", "SHOC2", "SHPRH", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC38A2", "SLC44A1", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A6", "SMAD4", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMG1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SNIP1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SULT1A4", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "TAB1", "TAF10", "TAF2", "TAF6L", "TAGLN2", "TALDO1", "TAP1", "TAP2", "TARBP1", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D24", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCP11L1", "TDRD7", "TDRKH", "TECR", "TERF2IP", "TES", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGOLN2", "TGS1", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THTPA", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM87A", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMX2", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRAF2", "TRAP1", "TRAPPC4", "TRIM21", "TRIM24", "TRIM26", "TRIM27", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", 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"results/proteins/hek293t_core/pharos_dto/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9c92c2938c0abe763697649ba51e0034d3e027e2 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,68 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter 0.5178087346047752 4.081252371587835 4.479368468546241e-05 0.0947406453644065 0.0005875186642041 210 Q9BQE5,P53007,P28288,Q9H2J7,Q03518,Q8TEM1,P24390,P49257,Q70HW3,P49755,P08183,Q7Z3B4,Q9UEU0,Q9BVK6,O43772,Q9UPT5,Q9BSK2,Q9HD45,Q9P2W9,Q02978,Q96QD8,Q9Y619,Q8TB61,Q9HC07,Q9H2D1,Q9UBX3,Q9Y6C9,Q8WWI5,Q9NZJ7,P36542,Q9HC21,Q86VD7,O60499,Q9UNK0,P35670,Q9H0U3,P33527,Q9P253,P56134,Q6KCM7,Q8IXU6,P08195,O43760,Q9H6H4,Q99805,O75746,P16615,Q15388,Q9Y6M7,Q9NWU2,Q15070,Q15363,P53985,Q9H270,Q9H9B4,Q9Y5J6,P12236,P20020,P17900,Q15758,P13473,Q93050,Q12846,P11279,O96008,O95202,P30825,O95563,O15400,P24539,P05023,O43808,Q7L0J3,Q5SQN1,Q00765,Q6NUK1,P12235,P05141,Q92544,O14678,Q96NB2,Q86Y82,Q92581,P56385,P51572,O75947,Q8TBP6,Q9UJS0,P41440,P06576,Q03519,Q9Y3A6 92 +SLC superfamily of solute carriers 0.7228628002323815 3.992241615007287 6.545163342308591e-05 0.1353567536636462 0.0005940746684348 50 Q9NZJ7,P53007,Q9HC21,Q86VD7,Q9H2J7,Q9H0U3,Q6NUK1,P12235,P05141,Q6KCM7,Q8IXU6,Q70HW3,P08195,Q96NB2,O95202,P30825,Q92581,O75746,O43772,O95563,Q9BSK2,Q9Y6M7,Q8TBP6,Q02978,Q9UJS0,Q96QD8,P53985,P41440,Q9Y619,O43808,Q8TB61,Q9HC07,Q9H2D1,Q9H9B4,Q7L0J3,P12236,Q9UBX3,Q9Y6C9,Q8WWI5 39 +SLC25 family of mitochondrial transporters 0.807859110244296 3.4940938274724385 0.0004756738101701 0.652572290903471 0.0016803612181207 23 Q9NZJ7,P53007,Q9HC21,Q86VD7,Q6NUK1,P12235,P05141,Q6KCM7,Q70HW3,O43772,Q9BSK2,Q8TBP6,Q02978,Q9UJS0,O43808,Q9H2D1,P12236,Q9UBX3,Q9Y6C9 19 +Mitochondrial nucleotide transporter subfamily 0.8853521126760451 2.9052213191908094 0.0036699349791999 0.999716867522752 0.0073864089889333 11 O43808,Q9HC21,Q86VD7,Q9H2D1,Q6KCM7,Q70HW3,Q9BSK2,P12236,Q6NUK1,P12235 10 +Oxidoreductase 0.4622739201039121 2.8155695111362 0.0048690862368165 0.9999805085572168 0.009302759774898 119 P14406,O43169,O15260,Q8N0U8,Q16850,Q9UBM7,P15954,Q9Y6M9,Q16134,Q9UDW1,Q9NZ01,P21912,P00374,Q15392,O76062,O95168,Q8N4Q0,P51970,Q9H7Z7,P03886,P00403,Q13423,P49748,O95881,Q9P0J0,Q8TED1,Q14534,Q15800,Q14739 29 +Miscellaneous SLC25 mitochondrial transporters 0.9637538634447878 2.7189026254124 0.0065498886993138 0.9999995444338476 0.0117749617232001 2 Q9Y6C9 1 +SLC35 family of nucleotide sugar transporters 0.9511098623208754 2.6652420809014714 0.0076932919946695 0.9999999647426032 0.0134921032455845 2 Q8TB61 1 +Receptor 0.5978698774325354 2.6075971758777756 0.0091180185566854 0.9999999985521254 0.0154776449449619 31 Q6NTF9,Q9NR77,Q14108,Q12959,O75381,Q13432,Q567V2,Q9BUN8,Q9UQB8,A6NIH7,Q8WTV0 11 +Intracellular calcium-sensing protein 0.7440518358730674 2.4987694965544245 0.0124625343277322 0.9999999999992092 0.0198792184323195 14 Q9BRK5,P80303,P41208,Q14257,Q02818 5 +Calmodulin 0.7440518358730674 2.4987694965544245 0.0124625343277322 0.9999999999992092 0.0198792184323195 14 Q9BRK5,P80303,P41208,Q14257,Q02818 5 +Glycosyltransferase 0.6935780438709557 2.433419805479109 0.014956948247071 0.9999999999999972 0.0232570601854386 17 Q8N4A0,Q8N128,P61803,Q16739,P46977,Q9BT22,Q86SF2,P04843,Q8TCJ2,Q10472,Q8N6G5 11 +Calcium-binding protein 0.6630799986935348 2.4146369476081744 0.0157509006014293 0.9999999999999996 0.0243045146780389 19 Q9BRK5,P43307,P80303,Q02818,Q14257,P41208 6 +Reductase 0.6881731677103615 2.4030314129481027 0.0162597906271724 1.0 0.0249167274300531 17 O95881,Q9H7Z7,Q9UDW1,Q14739,Q15392,P00374,Q9UBM7,O76062 8 +Oxidase 0.6171933103874783 2.182378191851735 0.0290816324787097 1.0 0.0404883379496823 20 P14406,O75880,P49748,O43169,O15260,Q15800,P15954,O15254 8 +Serine protease 0.5602009469314543 2.1343851415186785 0.0328112668605795 1.0 0.0447279969105569 27 Q9H3G5,O14773,Q9HB40,P42785,P67812 5 +SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 0.8069682495082815 2.0317597490754187 0.0421779838660649 1.0 0.0553243684476956 2 P30825 1 +Chloride channel family 0.8021916268614736 2.0101095955163255 0.0444195907162221 1.0 0.0579567413807666 2 P51790 1 +SLC56 Sideroflexins 0.790109581343067 1.9551758725971784 0.0505623153347301 1.0 0.0645686578584886 2 Q96NB2 1 +Membrane trafficking regulatory protein 0.5272040947126344 1.820825727317411 0.0686333521843911 1.0 0.0832441640577058 25 Q9P253,P13473,P24390,O43760 4 +Ribosomal protein 0.3846320978670969 1.8015947605008285 0.0716091862223458 1.0 0.0862051753894815 108 Q96GC5,P55795,Q02878,P52597,P39023,P27635,P61927,Q96A35,Q9NWU5,P84098,P18124,P31943,Q9BYD1,P62266,P46779,P62424,Q9BYD2,P46776,P49406,P47914,P40429,Q8IXT5,P46778,O76021,O60506,P62917,Q9Y3B7,Q5T653,Q07020,P61313,P83881,Q9Y2R9,Q9HD33,Q9Y3U8,P82912,P31942,P18077,Q8TDN6,Q9Y3A4,P62847,P62854 41 +SNARE protein 0.6204026634454406 1.754881903878806 0.0792795101024956 1.0 0.0942027120041419 13 Q9UEU0,O60499,O15400,Q9P2W9,Q12846,Q5SQN1,Q86Y82 7 +Signaling 0.5422683029777738 1.703952105941303 0.0883900352662367 1.0 0.1031628308201917 20 O00264,Q07820,P43490,O15173,Q8IZ81,Q8WUJ1 6 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.8322091062394628 1.694762671715505 0.0901204513537421 1.0 0.1047868356399869 3 Q9UBX3,P53007 2 +P-type ATPases 0.6562789243189897 1.671652501612578 0.094592865476776 1.0 0.1092439433936571 9 P16615,P35670 2 +Oxygenase 0.8032924884189202 1.670232318896407 0.0948734080092637 1.0 0.1094541602266791 5 Q16850 1 +F-type ATPase 0.7188447440324529 1.6104854535041628 0.1072919185780012 1.0 0.121389272942023 7 P56385,P36542,O75947,P06576,P24539 5 +Mitochondrial amino acid transporter subfamily 0.7646462646649995 1.5983772650943555 0.1099590412008901 1.0 0.1238990819210841 6 Q9UJS0,O43772,Q8TBP6,Q9Y619 4 +Phospholipase 0.7839513368938422 1.5907846203505545 0.1116580553036032 1.0 0.1253051509518214 5 Q8NCC3 1 +Lipase 0.7596030395090441 1.5771941224320978 0.1147508649925677 1.0 0.128257757552055 6 Q8NCC3 1 +Lipid kinase 0.6863494106727227 1.4648169218226548 0.1429708737989705 1.0 0.1536176409967662 7 Q9NRA0 1 +Phosphatase inhibitor 0.7250018716331345 1.4311232136979404 0.152394905345544 1.0 0.162798788306634 6 Q01105,Q99733 2 +Phosphatase modulator 0.6306651638341697 1.416358069726952 0.1566706938679292 1.0 0.1671254353214299 8 Q01105,Q99733 2 +ATP-binding cassette transporter family 0.6742116403867104 1.4100757129063402 0.1585173278196276 1.0 0.1689330946835552 7 P28288,P08183,Q03519,Q03518 4 +Aspartic protease 0.7526290844634548 1.3568620466990875 0.1748250481633053 1.0 0.1859556041258327 4 Q8TCT8,Q5BJF2 2 +Acyltransferase 0.5912962127799682 1.3469701476934357 0.1779898473162646 1.0 0.1891408133604687 9 P49354 1 +CDK1 subfamily 0.6507445911772932 1.3083363283637797 0.190759258409259 1.0 0.2026133232243659 2 P24941 1 +Heterotrimeric G-protein 0.5745478395356499 1.2622446550551494 0.2068607648384368 1.0 0.2194007730171869 9 Q9UBI6,Q8NHH9,P09471,P63218 4 +ABCB subfamily 0.679602424661802 1.1573938654502824 0.2471114792401674 1.0 0.2610944873379229 5 P08183,Q03519 2 +KRAB box transcription factor 0.7008370816727671 1.146951599182522 0.2514016252492159 1.0 0.2653750172464407 4 P49711 1 +C2H2 zinc finger transcription factor 0.7008370816727671 1.146951599182522 0.2514016252492159 1.0 0.2653750172464407 4 P49711 1 +Na+/K+-ATPases 0.6919617762788125 1.1216430197276837 0.2620142525871234 1.0 0.2760529489087663 3 P05023,P05026 2 +Metalloprotease 0.3877805435014558 1.1105879525939706 0.266745750786197 1.0 0.2809047669416728 40 P14735,Q99797,Q10713,P53582,P42892,P22695,O75844,Q9NZ08,Q7Z2K6,Q8TAQ2,P55786,Q92905,P51665,Q96TA2 14 +Epimerase/racemase 0.5140407604694643 1.1014674170773706 0.2706932778488622 1.0 0.2847918860701571 12 Q9NRG7,P40939,Q13011 3 +SLC12 family of cation-coupled chloride transporters 0.6517706576728548 0.9588102216704714 0.3376543588620602 1.0 0.3532335147794245 3 Q9BXP2,P55011 2 +F-type and V-type ATPases 0.45817177393578 0.9306873980903434 0.3520152902698616 1.0 0.3679106185228752 15 P56385,P56134,P36542,Q93050,O75947,Q9Y487,P06576,P24539 8 +Ca2+-ATPases 0.630659213821965 0.8660227149740534 0.3864777052560781 1.0 0.4024149302150917 4 P16615 1 +Protease 0.3168809744702199 0.8566535934808184 0.3916363573840267 1.0 0.4075953096521345 122 P10619,Q5BJF2,Q8TCT8,P42892,O75844,Q7Z2K6,Q9H3G5,P55786,O14773,Q92643,P67812,Q13510,P42785,Q9HB40 14 +Ion channel 0.4843787729312604 0.8453344457196192 0.3979241341196808 1.0 0.4139454241638253 10 Q4KMQ2,P0CG08,Q9C0H2,Q96S66 4 +Esterase 0.4669251846223518 0.8417668255066495 0.3999184845998351 1.0 0.4158253967154112 12 Q9UMR5,P50897 2 +Chromodomain 0.595629441220443 0.7300072272340615 0.4653857669317927 1.0 0.4823167789750202 4 P83916,Q13185 2 +Extracellular structure 0.4688401748055839 0.7285687797943188 0.4662654817238847 1.0 0.4830032169652549 9 Q96CW1,Q92791,O75718,Q32P28,P55081 5 +Cell-cell junction 0.5186850238831051 0.7066163875747943 0.4798049022313526 1.0 0.4961035331587089 2 Q07157 1 +Tight junction 0.5186850238831051 0.7066163875747943 0.4798049022313526 1.0 0.4961035331587089 2 Q07157 1 +SLC27 family of fatty acid transporters 0.5068839561674627 0.6565087161051811 0.5114968613074222 1.0 0.5276443945334689 2 O14975 1 +Hsp90 family chaperone 0.5316277762159005 0.4961936931815068 0.6197577602536575 1.0 0.6357810449139552 4 P07900,P08238,Q12931 3 +CK1 group 0.524015805001095 0.4778429204661135 0.6327620100571376 1.0 0.6482236912618533 3 Q86Y07 1 +Lyase 0.3407425047827428 0.3816142347654345 0.7027475241174712 1.0 0.715958275373233 22 O96005,Q96KA5,P53701,O95900,P22830 5 +Extracellular matrix glycoprotein 0.4779308405959985 0.3237399487124732 0.7461349235297385 1.0 0.7577293419026869 4 Q9Y2T2,Q96CW1,Q32P28 3 +Non-protein kinase 0.3255986641956387 0.2986986748772011 0.7651699682166719 1.0 0.7763505339623037 23 Q9NRA0,Q9UIJ7 2 +Eph family 0.3885923012082075 0.2390002494515617 0.8111053893114049 1.0 0.8207086407331246 2 Q15375 1 +Growth factor 0.4151965982044204 0.1894415118824926 0.8497467916865074 1.0 0.8590251915957322 5 Q5JRA6,Q96PC5 2 +Nucleotide phosphatase 0.3530280033678745 0.1693105194472301 0.8655524021134005 1.0 0.8742079261345345 8 O43681,O95140,Q9H857 3 +DNA glycosylase 0.3425119415566225 0.136846476550345 0.8911521462096599 1.0 0.8988379795178685 2 P78549 1 +Glycosylase 0.3425119415566225 0.136846476550345 0.8911521462096599 1.0 0.8988379795178685 2 P78549 1 +MAPK family 0.3707138842046152 0.0978815143612219 0.9220263788940636 1.0 0.928713786900548 3 Q16539,P27361 2 +Protease inhibitor 0.2819650449477984 0.0083733475217956 0.9933191133596572 1.0 0.998681923541502 14 P27105,P05067,P50454 3 +Hydrolase 0.2558237966945552 0.0082952241376383 0.9933814446368854 1.0 0.998681923541502 108 Q8N2A8,O43924,Q9UMR5,Q9UKK9,Q9H857,Q5T9A4,P11117,Q8NCC3,Q9NVI7,O43681,Q9NPH0,P50897,P10253,P16278,Q86YN1,Q969T7,P00813 17 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7d9fb5ecf7406a024bdc36cfea4c553d9308660a --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1,4-alpha-glucan-branching enzyme", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-Ketosteroid receptors", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L27, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "4-aminobutyrate aminotransferase, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMP deaminase 2", "AMPK subfamily", "AN1-type zinc finger protein 1", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-1A", "AP-1 complex subunit sigma-2", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AT-rich interactive domain-containing protein 3B", "AT-rich interactive domain-containing protein 4A", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 6, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Acetoacetyl-CoA synthetase", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A synthetase 2-like, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 2/3 complex subunit 5", "Actin-related protein 3", "Activating signal cointegrator 1", "Activin receptor type-1b", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Adenylyltransferase and sulfurtransferase MOCS3", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amylase", "Amyloid-beta A4 protein", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Arsenite methyltransferase", "Arylsulfatase A", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atherin", "Atlastin-2", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase a", "Aurora kinase b", "Autophagy protein 5", "B-cell receptor-associated protein 31", "BET1 homolog", "BTB/POZ domain-containing protein KCTD12", "BTB/POZ domain-containing protein KCTD15", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2 homologous antagonist/killer", "Bcl-2-associated transcription factor 1", "Beta-adducin", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breakpoint cluster region protein", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CAP-Gly domain-containing linker protein 1", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CCR4-NOT transcription complex subunit 7", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CLK family", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "COUP-TF-like receptors", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding mitochondrial carrier protein SCaMC-2", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-2", "Caspase-8", "Catechol O-methyltransferase", "Catechol O-methyltransferase domain-containing protein 1", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell surface glycoprotein MUC18", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Centrosome-associated protein CEP250", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 6", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline transporter-like protein 1", "Choline/ethanolamine kinase family", "Chondroitin sulfate N-acetylgalactosaminyltransferase 2", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 2", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Copper-transporting ATPase 2", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1C", "Coronin-7", "Coup transcription factor 1", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cu+-ATPases", "Cullin-1", "Cullin-2", "Cullin-4A", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-A2", "Cyclin-K", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoplasmic dynein 2 light intermediate chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DCK/DGK family", "DDB1- and CUL4-associated factor 13", "DDB1- and CUL4-associated factor 8", "DEP domain-containing protein 1B", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA fragmentation factor subunit beta", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA repair endonuclease XPF", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase III subunit RPC5", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(14)-sterol reductase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidine kinase", "Deoxycytidylate deaminase", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large homolog 1", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Dr1-associated corepressor", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity protein kinase clk3", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase DTX3L", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase XIAP", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D1", "EF-hand domain-containing protein D2", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelial protein C receptor", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 2", "Ephrin type-a receptor 7", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethanolamine kinase 1", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Fanconi anemia group J protein", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Folate transporter 1", "Folylpolyglutamate synthase, mitochondrial", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GEK subfamily", "GHMP kinase family", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GPN-loop GTPase 1", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Gamma-tubulin complex component 4", "Ganglioside GM2 activator", "Gap junction-forming innexin (innexin) family", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIH subunit 1", "General transcription factor IIH subunit 4", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucocorticoid receptor", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase 1-like protein", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein G(o) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock factor protein 1", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase 3", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD2", "Histone-lysine N-methyltransferase SETD7", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol polyphosphate 5-phosphatase OCRL-1", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin heavy chain isoform 5C", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF15", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinetochore protein NDC80 homolog", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Lethal(3)malignant brain tumor-like protein 3", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Leukocyte elastase inhibitor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase inducer phosphatase 3", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 3", "MAPK family", "MARK subfamily", "MBT domain", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "Magnesium transporter protein 1", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mediator of RNA polymerase II transcription subunit 12", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 25", "Mediator of RNA polymerase II transcription subunit 27", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D1", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7B", "Mevalonate kinase", "Mevalonate kinase subfamily", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial coenzyme A transporter SLC25A42", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim10 B", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial mRNA pseudouridine synthase TRUB2", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mothers against decapentaplegic homolog 4", "Mpv17-like protein 2", "Mucosa-associated lymphoid tissue lymphoma translocation protein 1", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "Myotubularin-related protein 6", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 50", "N-sulphoglucosamine sulphohydrolase", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neural Wiskott-Aldrich syndrome protein", "Neurofibromin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Neutral cholesterol ester hydrolase 1", "Nf-kappa-b essential modulator", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear cap-binding protein subunit 2", "Nuclear envelope pore membrane protein POM 121C", "Nuclear factor related to kappa-B-binding protein", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase 3", "Nucleoside diphosphate kinase A", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PDZ domain-containing protein GIPC1", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PITSLRE subfamily", "PKA family", "PKC delta subfamily", "PKC family", "PKC iota subfamily", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pannexin-1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylase b kinase regulatory subunit beta", "Phosphorylated adapter RNA export protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polypeptide N-acetylgalactosaminyltransferase 4", "Polyribonucleotide 5'-hydroxyl-kinase Clp1", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presequence protease, mitochondrial", "Primase", "Probable ATP-dependent RNA helicase DHX34", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein DDI1 homolog 2", "Protein ENL", "Protein ERGIC-53", "Protein FAM177A1", "Protein Hook homolog 2", "Protein Hook homolog 3", "Protein LSM14 homolog B", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SEC13 homolog", "Protein SET", "Protein Wiz", "Protein XRP2", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase c delta type", "Protein kinase c zeta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyridoxine-5'-phosphate oxidase", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIO family", "RIO2 subfamily", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase II subunit A C-terminal domain phosphatase", "RNA polymerase-associated protein LEO1", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-1", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab proteins geranylgeranyltransferase component A 2", "Rab3 GTPase-activating protein non-catalytic subunit", "Rab5 GDP/GTP exchange factor", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoblastoma-associated protein", "Retinoblastoma-like protein 1", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rhomboid domain-containing protein 2", "Riboflavin kinase", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p20", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SCY1 family", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC19 family of vitamin transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC4 family of bicarbonate transporters", "SLC44 choline transporter-like family", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLC9 family of sodium/hydrogen exchangers", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "STKR Type 1 subfamily", "STKR family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Scy1-like protein 2", "Sec1 family domain-containing protein 1", "Sec1 family domain-containing protein 2", "Secretory carrier-associated membrane protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Secretory carrier-associated membrane protein 4", "Segment polarity protein dishevelled homolog DVL-2", "Selenide, water dikinase 1", "Selenocysteine lyase", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 1", "Sentrin-specific protease 3", "Separin", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-8", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 2", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase rio2", "Serine/threonine-protein kinase smg1", "Serine/threonine-protein kinase tousled-like 2", "Serine/threonine-protein kinase ulk3", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent HCO3- transporters", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/hydrogen exchanger 6", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 7", "Solute carrier family 12 member 9", "Solute carrier family 25 member 33", "Solute carrier family 25 member 40", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Sphingosine kinase 2", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Synaptosomal-associated protein 47", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "T-complex protein 11-like protein 1", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TBC1 domain family member 10A", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 24", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TLK family", "TNF receptor-associated factor 2", "TOPK family", "TP53-binding protein 1", "TRIO family", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Torsin-1A", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Trans-Golgi network integral membrane protein 2", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription factor p65", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 10", "Transcription initiation factor TFIID subunit 2", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor CTCF", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation initiation factor", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 115", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-2", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Triple functional domain protein", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tuberin", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-3 chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin gamma-1 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tudor domain-containing protein 7", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase yes", "Tyrosine-protein phosphatase non-receptor type 9", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm8", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucuronic acid decarboxylase 1", "ULK family", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog A", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 22", "Ubiquitin carboxyl-terminal hydrolase 33", "Ubiquitin carboxyl-terminal hydrolase 34", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Unconventional myosin-Va", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 11 homolog", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuolar protein sorting-associated protein 52 homolog", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle transport through interaction with t-SNAREs homolog 1B", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 82", "WD repeat-containing protein 92", "WNK family", "Werner syndrome ATP-dependent helicase", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "Zinc finger protein 277", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zyxin", "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-capping enzyme", "mRNA-decapping enzyme 1A", "mRNA-decapping enzyme 1B", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AACS", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "AMPD2", "ANAPC1", "ANGEL1", "ANO6", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOL2", "APP", "ARCN1", "ARFIP1", "ARFIP2", "ARHGDIA", "ARID3B", "ARID4A", "ARIH1", "ARIH2", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "AURKB", "BAG6", "BAIAP2", "BAK1", "BCAP31", "BCAS2", "BCAT2", "BCKDK", "BCLAF1", "BCR", "BET1", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD3", "BRIP1", "BRIX1", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP8", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2AIP", "CEBPZ", "CEP170", "CEP250", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHML", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLIP1", "CLK3", "CLNS1A", "CLP1", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DDAH2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DEPDC1B", "DERL1", "DERL2", "DFFB", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX34", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLG1", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DRAP1", "DSC3", "DSG2", "DSP", "DST", "DTX3L", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENO2", "EPHA2", "EPHA7", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC4", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTA", "FOXRED1", "FPGS", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GID8", "GINS2", "GIPC1", "GLB1", "GLB1L2", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GPAT4", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2H1", "GTF2H4", "GTF3C3", "GTF3C5", "GTPBP1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK2", "HOOK3", "HPRT1", "HSD17B10", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKG", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KCTD15", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEO1", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM8", "LTN1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MALT1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS2", "MAT2A", "MBOAT7", "MCAM", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED12", "MED14", "MED25", "MED27", "METAP1", "METTL1", "METTL7B", "MFAP1", "MFN1", "MFN2", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MLLT1", "MMS19", "MOCS3", "MORF4L1", "MORF4L2", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVK", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA10", "NAA15", "NAA25", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCEH1", "NCL", "NCOA5", "ND1", "NDC80", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA8", "NDUFA9", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEDD4", "NEDD4L", "NEK9", "NF1", "NFRKB", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NME1", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA1", "NPEPPS", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN3", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCRL", "OLA1", "OPA1", "ORC3", "ORC5", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "PACSIN2", "PAICS", "PAIP1", "PAK2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PAPSS2", "PARG", "PARK7", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN1", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCD3", "PLCG1", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POM121C", "POP7", "PPA1", "PPA2", "PPAT", "PPIL1", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA2", "PRKACA", "PRKAG1", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN9", "PTPRF", "PUDP", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGEF1", "RABGGTA", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RB1", "RBBP6", "RBL1", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "RELA", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIOK2", "RIPK1", "RNASEH2A", "RNF14", "RNGTT", "RNH1", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RTCA", "S100A10", "S100A11", "SAE1", "SAMD1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCPEP1", "SCYL2", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SGSH", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A6", "SLK", "SMAD4", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMG1", "SMN1*", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPHK2", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK26", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "TAB1", "TAF10", "TAF2", "TAF6L", "TAGLN2", "TAP1", "TAP2", "TARS", "TARS2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D24", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TCP11L1", "TDRD7", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM10B", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TLK2", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM165", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRIO", "TRIP4", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSG101", "TSPYL1", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBP1", "UCHL5", "UCK2", "UGCG", "UGGT1", "ULK3", "UNC119", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP33", "USP34", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "UXS1", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS11", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS52", "VRK1", "VRK2", "VTI1B", "WARS", "WASF2", "WASHC5", "WASL", "WDHD1", "WDR1", "WDR82", "WDR92", "WIZ", "WNK1", "WRN", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS4", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZC3H7B", "ZCCHC11", "ZCCHC8", "ZFAND1", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF207", "ZNF277", "ZNF281", "ZNF598", "ZNF622", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCC1", "ABCD3", "ABCD4", "ACADVL", "ACOX3", "ACP2", "ACP6", "ADA", "AK3", "ALG1", "ANO6", "AP2M1", "AP3M1", "APOL2", "APP", "ASAH1", "ASNA1", "ATAD3A", "ATAD3B", "ATL2", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6V0A1", "ATP6V0A2", "ATP7B", "BAIAP2", "BCAP31", "BRIX1", "CBX1", "CBX3", "CDK2", "CETN2", "CLCC1", "CLCN3", "CLPTM1", "CLPTM1L", "COPS5", "COX2", "COX7A2", "COX7C", "CPVL", "CRTAP", "CSGALNACT2", "CTCF", "CTSA", "CYB5B", "CYB5D2", "CYP51A1", "DAD1", "DERL1", "DHCR24", "DHCR7", "DHFR", "DLG1", "DOLPP1", "ECE1", "ECH1", "ELMOD2", "EPHA7", "ERAP1", "ERMP1", "ETFDH", "EXOC7", "FAM177A1", "FECH", "FNTA", "GAA", "GALNT1", "GALNT4", "GALNT7", "GID8", "GLB1", "GM2A", "GNAO1", "GNG12", "GNG5", "GPR89B", "GPX8", "HADHA", "HCCS", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HSP90AA1", "HSP90AB1", "IDE", "KDELR1", "LAMP1", "LAMP2", "LBR", "LETM1", "LMAN1", "MAGT1", "MAPK14", "MAPK3", "MCL1", "METAP1", "MFAP1", "MFN2", "MIA2", "MIA3", "MIPEP", "MPC2", "MPV17L2", "MRPL11", "MRPL13", "MRPL19", "MRPL2", "MRPL22", "MRPL24", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS7", "MSMO1", "MTCH1", "MTCH2", "NAMPT", "NAP1L4", "ND1", "NDUFA13", "NDUFA8", "NDUFB4", "NDUFB9", "NNT", "NPEPPS", "NT5C3B", "NT5DC2", "NTHL1", "NUCB1", "NUCB2", "NUDT5", "NUP210", "NUP54", "OXA1L", "P3H1", "P3H4", "PDE6D", "PEX14", "PGRMC1", "PGRMC2", "PIGK", "PLA2G15", "PLD6", "PMPCA", "PPT1", "PPT2", "PRCP", "PSMD7", "PTGES2", "PXMP2", "RBM12B", "RCN2", "REEP4", "REEP5", "RHBDD2", "RPL10", "RPL13A", "RPL15", "RPL18", "RPL19", "RPL21", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL6", "RPL7", "RPL7A", "RPL8", "RPN1", "RPS23", "RPS24", "RPS26", "RRP7A", "RSL1D1", "SCARB1", "SCARB2", "SCO1", "SCPEP1", "SDF4", "SDHB", "SDR39U1", "SEC11A", "SERPINH1", "SET", "SFXN1", "SFXN2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC44A1", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A6", "SMARCC2", "SNAP47", "SPHK2", "SPPL2A", "SQLE", "SSR1", "STOM", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX4", "STX7", "STX8", "SURF4", "SV2A", "SYNCRIP", "SYNGR2", "TAP1", "TAP2", "TECR", "TIMM10B", "TJP1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM165", "TMEM97", "TOMM20", "TOMM40", "TPP1", "TRAP1", "TRUB2", "TTYH3", "TXNDC12", "UGCG", "UNC119", "UNC119B", "UQCR10", "UQCRC2", "VKORC1L1", "VPS11", "VPS18", "VRK2", "VTI1B", "YME1L1", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d9752f64bcde7c3d52fb03a0871b9304fad457d3 --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio", "1": "Tdark"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4982d5a073dc01059fa07df6f76ba0ec73ee36d6 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4bbc4d8cda725d7d7278206f51aaf748b39bfb70fb56eb93f1b4e57968d62b95 +size 210721 diff --git a/pharos_protein_category/advanced/plot_1.png b/pharos_protein_category/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..3f99cd50e9d15113f078aa2d2bd9138108945ed5 --- /dev/null +++ b/pharos_protein_category/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71157bb607a71e384bfba2abcd4723f7cf363e38456ed455eed72517ddd04229 +size 209195 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1e34e34f6a79d9cccb1734a1422c265c7ec5c879 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tbio", "1": "Tdark", "2": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..35bc9e0674b0774222600fe887a5aaf96ee8427d --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5de54a9be3465c9884acf77b9b6c301d5c0102994ddffa2b9265a8b624e72668 +size 132293 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..5bdbfdfa7c54a323b67b077579f76d1858849690 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f98e02acf7cc8c94429bc5de4faafab806150496301c5df882dcadef027a8a5e +size 138170 diff --git a/pharos_protein_category/basic/plot_2.png b/pharos_protein_category/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..88cdc239b3a3dfe0d4cdc69849df79774af349e0 --- /dev/null +++ b/pharos_protein_category/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3562c0db4f310db0b8c607d31bea1a394b053ae191741654ed12de39ebba0ea6 +size 133166 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e4d9f24e0f4046e972470b8a9f7b8547ed5a2b0c --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f97170c0c530d81f4fece6afa145a99d9b0d93c2e7e52f2b4601467c1fb2138d +size 90112 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9b0a1b4ecc077109a94c267f451ace1c4672cf48 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tbio 478 2722 3.133523336958605 0.0017272118323532 467.6796116504854 2434.25 -0.5416405556668178 0.3215141878443288 119.73666199244032 234.70955636597876 4.704421961664106 0.4116627836259234 0.94979080855668 0.9804805555215306 0.978185334504559 0.8486357381135203 0.3590238644212091 +Tdark 99 387 2.797937249248001 0.0051430103302017 74.3131067961165 324.373786407767 0.5859664552431031 0.6577158703271868 20.515717939687796 49.369088361677456 1.229854636263473 0.4013924214985833 0.7393059708197018 0.6436586364406599 0.8530043922804083 0.927992679277062 0.9852638254518492 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ab258ba2ddf8a7993ebfd03842b406a9ede73085 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 890.0 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ac90b91bc2ffb04656133c6ba63564323c4ce093 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0c21ee5e690f25956bb1b64d2d35a49b70d3a005 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tbio 0.1880653254596861 3.133523336958605 0.0017272118323532 0.006890968367123 0.0069088473294129 2722 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478 +Tdark 0.3849168541450541 2.797937249248001 0.0051430103302017 0.0204138814315512 0.0102860206604034 387 Q9P0I2,P14406,Q96GC5,Q8WWC4,O60830,Q8N128,Q8N4V1,Q69YU5,O15126,O75964,Q15629,Q6UW02,Q8N8L6,P82933,Q8N4H5,P82663,Q8WVI0,Q9NX00,Q5TC12,Q86YQ8,Q9BVK6,Q9H1E5,Q5T653,Q96GQ5,Q5VW38,Q8NBN7,Q9HD45,Q86YN1,O94919,Q96EY4,O75071,Q9NR77,Q9BXW7,Q9NPR9,Q9BYN8,Q3SXM5,Q7Z2K6,O95070,Q9HD20,Q8NBN3,Q96CP7,Q9NRY5,Q5SR56,Q9H4I3,Q8IWB1,Q96SK2,Q96LJ7,Q9HC38,Q8IXU6,Q6UW68,Q99805,Q5SNT2,Q9P0S9,Q8NC54,Q9Y5J6,Q6ZXV5,Q9Y3A4,Q8NE00,Q5W0Z9,Q8WUJ1,Q15005,Q9Y5M8,Q8WVC6,Q9NRG7,Q70UQ0,Q96ER9,Q9BU23,Q6IAN0,Q96M27,Q5SWX8,O95900,Q8NC44,Q9Y320,Q9Y3E0,Q5SQN1,Q969T7,Q96IX5,Q9NPL8,Q9NPA0,P0CG08,O43615,Q8IYS2,Q9NWU5,Q9UNL2,Q8TBQ9,Q5J8M3,P15954,Q9BRJ2,Q9H857,Q96NB2,Q96SB3,Q5T3I0,Q96CN7,P82930,Q8TBP6,Q9Y5Q8,Q9H0R1,Q5R3I4,Q9UKR5 99 +Tclin 0.40263076497054 1.952349506032803 0.0508967235767809 0.1885647119731467 0.0678622981023746 101 O43924,Q16739,P49721,Q99720,P04035,P21964,O43676,Q9Y6M9,Q8N183,P00374,O95168,P51970,O96000,Q86Y39,P03886,P10253,P05023,Q9P0J0,Q7L0J3,P00813,Q9Y375,P38435 22 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a131c42710a1d9ea530880070340f6d298f0a0bd --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP5M1", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARID4A", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRI3BP", "BRIP1", "BRIX1", "BRMS1L", "BROX", "BRPF3", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C16orf58", "C16orf62", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "C7orf26", "C8orf33", "C8orf59", "CAB39", "CACTIN", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC59", "CCDC6", "CCDC8", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC123", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDR2L", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPI", "CENPK", "CENPQ", "CENPV", "CEP170", "CEP250", "CEP290", "CEP350", "CEP44", "CEP55", "CEP97", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHML", "CHMP1A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLN5", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG4", "COG5", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD2", "COMMD4", "COMMD7", "COMMD8", "COMMD9", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf38", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND4C", "DENR", "DEPDC1B", "DERL1", "DERL2", "DFFA", "DFFB", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAIM", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM234B", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAU", "FBL", "FBXL18", "FBXO21", "FBXO22", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1B", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTA", "FOCAD", "FOXK1", "FOXRED1", "FPGS", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAN", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH11", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "GXYLT1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2B", "ITPA", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KANSL3", "KARS", "KAT7", "KCMF1", "KCTD10", "KCTD12", "KCTD15", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIN", "KLC1", "KLC2", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIG4", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRR1", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYPLA1", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MALT1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP7D3", "MAP9", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVB12A", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NEO1", "NES", "NF1", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2C2AP", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN3", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGFOD1", "OGT", "OIP5", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHPT1", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCD3", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POM121C", "PON2", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB34", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG2", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RMND1", "RMND5A", "RNASEH2A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD1", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC14L2", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGSH", "SGTA", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPRH", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC44A1", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG5", "SMG8", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT1A4", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF10", "TAF2", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D24", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TCP11L1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX2", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "TGS1", "THADA", "THAP11", "THEM6", "THG1L", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THTPA", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLK2", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMCO6", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM104", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM41A", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM56", "TRIO", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR2", "TSR3", "TSTA3", "TTC1", "TTC19", "TTC27", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTI2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC16", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE3D", "UBE4A", "UBE4B", "UBFD1", "UBL5", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USE1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP32", "USP33", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXS1", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS11", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", 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3.5183496986754697e-06 1.2707066854905786e-06 +Antiport 7 9 2.16394566603649 0.0304685196243834 3.2063106796116503 7.097087378640777 0.8539962634551548 0.3166005193161004 2.0440914093762896 1.1428508308135348 1.2051823486844502 0.2998011899649158 1.0 1.0 1.0 0.3817570354203927 0.0002599861644489 +Amino-acid transport 7 8 2.138585091724724 0.0324692859600932 3.063106796116505 7.016990291262136 0.9299828460487652 0.271909550896337 1.9171930478617292 1.3907470472448622 1.1684874391815692 0.271335812648974 0.3968926535471839 1.0 0.2402159343378795 0.5022110525395543 0.0483158324013505 +Vision 4 6 2.105364749645378 0.0352595697838964 2.3470873786407767 5.992718446601942 1.08525596348634 0.2199144433248849 1.3876767838522928 1.281854462283163 1.178949427510656 0.2385050933787637 0.0087962585732332 0.0058319944063555 0.0016008508165985 0.0206613256108628 0.0060001681478776 +Sensory transduction 4 6 2.105364749645378 0.0352595697838964 2.3907766990291264 6.065533980582524 1.0901502088613606 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0000000000000000000000000000000000000000..36af830bc85572c187d807dd98c2b1533864012c --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 174, + "title": "Average number of proteins per term", + "value": 33.367816091954026 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..77c0daa057607372f6ba691a00ca66e482553d65 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2d27307c164886631a5554e2d90aeaf1e0accfc4 --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,50 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport 0.4739597227941541 4.5725402816799114 4.81846552635723e-06 0.000838063649856 0.0008384130015863 550 Q9BQE5,O60830,Q9NS69,O43169,Q99595,P53007,Q13432,Q8N4V1,P28288,P21796,O15126,Q12893,Q9H2J7,P45880,O75964,Q15629,Q03518,Q99720,Q8TEM1,O14949,O95197,P24390,Q96CU9,O43676,P49257,Q8N4H5,Q9Y282,Q9UDW1,Q70HW3,P49755,Q9Y6B6,P08183,Q7Z3B4,Q14849,Q13505,Q9C0H2,Q9UEU0,Q9BVK6,P22626,O00461,O43772,Q9H1E5,Q9UPT5,Q86Y39,Q9BSK2,Q9P2W9,P03886,Q02978,O75352,Q9BUN8,Q96QD8,Q2M389,Q9BTX1,Q9Y619,Q5JVF3,Q8TB61,Q9H2D1,Q8N5M9,O95070,Q9UBX3,Q9NX14,Q9Y6C9,Q9HD20,O14828,Q8WWI5,Q9Y5J9,Q9NZJ7,Q9UGP8,P36542,Q9HC21,Q86VD7,O60499,Q9UNK0,P35670,Q5SR56,O15118,Q9H0U3,Q5T8D3,P61026,P33527,Q969M3,O43674,Q5BJH7,Q9P253,O14925,P56134,Q9H0H5,Q9Y6M9,Q6KCM7,P36543,Q8IXU6,P14927,P21912,P41208,Q14728,O95864,P16615,Q9H3N1,Q9Y277,O15127,Q9Y6M7,Q15363,Q9UM00,P00403,Q9P0J0,Q9Y5J6,P12236,Q93050,Q969Q5,Q12846,P46379,Q9H4A6,P23786,Q6P4A7,Q96RL7,P08574,Q16134,O96008,Q96ER9,O95202,Q6P4Q7,O95168,P30825,P51970,O76054,O96000,O95563,A6NIH7,P24539,P05023,O43808,Q12981,Q8NHS3,Q7L0J3,Q9Y3E0,Q9UL25,Q9NR31,P0CG08,O43615,Q96S66,Q6NUK1,P12235,P05141,Q9NZ43,O14678,O43681,O75431,Q96AQ8,Q96NB2,Q86Y82,Q92581,Q4KMQ2,P56385,O75381,Q6DKK2,P51572,O75947,Q8TBP6,Q969X5,O15504,O75380,Q9UJS0,Q9H0R1,P61916,P41440,Q96SU4,P22695,Q9BXW6,P51790,O60826,P06576,Q03519,Q9Y3A6 173 +Lipid metabolism 0.5104184438589117 3.553244835585417 0.0003805101410623 0.0640763387220413 0.0066208764544845 141 Q16739,P09960,Q9H6V9,O15118,Q96G23,Q16850,Q06136,P37268,Q9UBM7,Q9UKU0,P23786,P04035,P48449,O15254,Q8NCG7,Q9UG56,A1L0T0,Q8NCC3,Q53GQ0,Q9NZ01,O00116,Q15392,O76062,O15121,Q12770,Q8NF37,O95864,Q8N5B7,Q9P035,Q9HCL2,Q9NUQ2,P0DMN0,Q9H7Z7,P04062,Q92604,Q6Y1H2,O00767,Q8NHP8,P51648,O14735,Q13510,P61916,Q8N2A8,P49748,P07602,Q99735,Q9NPH0,Q9UKR5,Q15800,P27544,Q13011,Q14739,P17900,Q96N66,P40939,O95470 56 +Electron transport 0.6423668905131192 3.358169211094646 0.0007846056710272 0.1276590837861237 0.0085734662898935 48 O95864,P00403,P51970,O43169,O43676,Q9H3N1,Q9Y6M9,P08574,Q9H1E5,Q16134,Q9UDW1,Q86Y39,Q9P0J0,P21912,P03886,O95168,O14949 17 +Ion transport 0.5832771592136592 3.0777858607402924 0.0020854471386457 0.3045851463742666 0.0181433901062182 62 P36542,P0CG08,Q93050,P21796,P35670,Q9H2J7,P45880,Q96S66,O75964,P56134,Q9H0H5,P36543,O96008,Q96AQ8,Q96ER9,O95202,Q6P4Q7,Q8NE01,Q92581,Q4KMQ2,P56385,Q9C0H2,P16615,Q9Y277,O75947,Q9Y6M7,Q9UM00,P24539,Q96QD8,P05023,P51790,P06576 32 +Respiratory chain 0.6229797930551106 3.0621492892695215 0.0021975382226804 0.3180455453689753 0.0182081738450664 35 O43674,O14949,Q96CU9,O43676,P08574,Q9Y6M9,Q9UDW1,P14927,O95168,P51970,O96000,Q6DKK2,Q86Y39,P03886,O75380,Q16795,P00403,P22695,Q9P0J0,Q9NX14 20 +Steroid biosynthesis 0.6597469406096214 2.721014232443319 0.0065081959402109 0.6789399770916958 0.0390491756412654 25 Q53GQ0,Q15800,Q16850,Q14739,Q15392,O76062,P37268,P48449 8 +Sphingolipid metabolism 0.8370693892454257 2.6842112534936753 0.0072701152254863 0.7190618685147123 0.0399276324855195 11 Q8N5B7,P07602,Q16739,P04062,Q9NZ01,P17900,Q13510,Q06136,O95470 9 +Steroid metabolism 0.6083241265936827 2.6830274677595525 0.0072958997736565 0.7203286829289125 0.0399276324855195 31 P61916,P0DMN0,P04062,O15118,Q9UKR5,Q15800,Q16850,Q14739,Q15392,O76062,P37268,Q9UBM7,Q12770,P04035 14 +Translocation 0.5514666613612129 2.6497976326313664 0.008053999677269 0.7551402914761981 0.0412175277601416 51 Q9BTX1,O60830,Q9NS69,O14925,Q99595,O75381,O15504,Q5JVF3,O43615,Q9Y5J6,Q15629,P41208,Q7Z3B4,Q8TEM1 14 +Sterol metabolism 0.6155249535783994 2.621187421317603 0.0087624075083898 0.783762519184459 0.0423516362905509 29 P61916,P04062,O15118,Q9UKR5,Q15800,Q16850,Q14739,Q15392,O76062,P37268,Q9UBM7,Q12770,P04035 13 +Cholesterol metabolism 0.6181883189838356 2.5385097963200915 0.0111325686124745 0.8574311019304112 0.0509754457518572 27 P04062,O15118,Q15800,Q16850,Q14739,Q15392,O76062,P37268,Q9UBM7 9 +Catecholamine metabolism 0.9081202584995776 2.480469093966036 0.0131209637941154 0.8995563005087541 0.054358278575621 2 P21964 1 +Lipid biosynthesis 0.5121597367520699 2.4671458722100064 0.0136194862173535 0.9080100829017655 0.0551114093446399 64 Q16739,Q96G23,Q16850,P37268,Q9UBM7,P48449,Q9UG56,Q53GQ0,Q9NZ01,O00116,Q15392,O76062,O15121,O95864,Q8NF37,Q9HCL2,Q9P035,Q9NUQ2,Q9H7Z7,Q92604,Q6Y1H2,Q15800,P27544,Q14739,Q96N66 25 +Leukotriene biosynthesis 0.8980050576004429 2.436470819978442 0.0148313660302554 0.925725410223398 0.0573479486503211 2 P09960 1 +Sterol biosynthesis 0.6553235696400382 2.3684856273135257 0.0178610743447675 0.9565400943667756 0.0661239773614799 19 Q15800,Q16850,Q15392,O76062,P37268 5 +Cholesterol biosynthesis 0.6799038706038493 2.3563216984890283 0.0184569258912532 0.9608952822154604 0.066906356355793 17 Q15800,Q16850,Q15392,O76062,P37268 5 +Peptide transport 0.8502388311323394 2.2260453989828535 0.026011140650751 0.9898048375356702 0.0794024293549242 2 Q03519 1 +Antiport 0.758525628244187 2.16394566603649 0.0304685196243834 0.995410417108223 0.0860206659250383 9 P05141,P41440,P12236,O95202,P51790,P12235,Q92581 7 +Amino-acid transport 0.7849704475091233 2.138585091724724 0.0324692859600932 0.9967961784007714 0.0882758712040035 8 Q9H9B4,Q9H2J7,P08195,Q96NB2,Q6P4A7,Q96QD8,P30825 7 +Vision 0.8880227589710398 2.105364749645378 0.0352595697838964 0.9980616893070384 0.0889154368463475 6 Q13432,O43924,P50897,Q6P4Q7 4 +Sensory transduction 0.8880227589710398 2.105364749645378 0.0352595697838964 0.9980616893070384 0.0889154368463475 6 Q13432,O43924,P50897,Q6P4Q7 4 +Phospholipid metabolism 0.6466300919068082 2.098577378386294 0.0358541722324314 0.9982588573081366 0.0891232281206153 16 Q8NF37,Q9HCL2,Q9NUQ2,Q9UG56,Q92604,Q9NPH0,O14735,Q96BW9,Q96N66 9 +Lipid transport 0.5596229009827944 2.013252341697654 0.044088089321064 0.9996085197161138 0.1050866786556868 24 Q9BQE5,Q4KMQ2,P61916,Q96SU4,O15118,Q99720,Q14849 7 +Apoptosis 0.3880665924078242 1.9088138399813357 0.0562861108410439 0.999958099389432 0.1255613241838672 134 Q9BXK5,Q9NZJ7,Q13232,Q15041,P21796,Q9UHX1,Q07820,Q96KA5,P46379,O95197,Q9UDX5,Q14728,Q66K74,P09601,Q96A26,Q9H3K2,Q12981,Q9P0J0,O14681,P12236,O60313,O95470 22 +Phospholipid biosynthesis 0.6200540786732597 1.8866174644918077 0.0592117960330194 0.9999755890754332 0.1286054501288123 15 Q8NF37,Q9HCL2,Q9NUQ2,Q9UG56,Q92604,O14735,Q96BW9,Q96N66 8 +GPI-anchor biosynthesis 0.8329088887119525 1.881764083733718 0.0598680543703091 0.9999783801348422 0.1286054501288123 6 Q92643,O43292,Q5H8A4 3 +ER-Golgi transport 0.463202358106063 1.8483482285671995 0.064551982998505 0.9999909338977608 0.1355299882551288 49 O95197,P24390,Q9NZ43,Q9NR31,Q12981,P49257,Q9Y282,P51572,P49755,O95070,Q9P2W9,Q969X5,Q15363 13 +Biomineralization 0.7516156223658219 1.778619997857023 0.0753020832482027 0.9999987866698696 0.1513049747517385 2 Q6P4Q7 1 +Neurotransmitter transport 0.8524451939291748 1.776488186376195 0.0756524873758692 0.9999988641050224 0.1513049747517385 3 Q7L0J3,Q12846 2 +Symport 0.6725659812656593 1.751727022271007 0.0798207580495864 0.9999994826277226 0.1526243066003081 9 P53985,Q9Y6M7,Q96QD8,Q9H2J7 4 +Calcium transport 0.654649925639871 1.7252294989462422 0.0844861215144474 0.9999997863523044 0.1587855869717829 10 O95202,P16615,Q9UM00 3 +Sodium transport 0.6417677787283398 1.599829328491107 0.1096364506214264 0.9999999983222674 0.1966674475064763 9 P05023,Q9Y6M7,Q96QD8,Q92581 4 +Hydrogen ion transport 0.5207190511018894 1.5265711418351569 0.1268676875432528 0.9999999999440332 0.2185641349755049 19 P56385,P56134,P36542,Q93050,P36543,O75947,Q9Y487,O75964,P06576,P24539 10 +ATP synthesis 0.6727378062146662 1.4034183532474809 0.1604921232351874 0.9999999999999396 0.2634493343671945 7 P06576,P56385,O75964,P36542 4 +Unfolded protein response 0.5852929279096928 1.3705279353549498 0.1705221612558258 0.9999999999999926 0.2747301486899416 10 Q15629 1 +Peroxisome biogenesis 0.7240022484541913 1.2526991107758465 0.2103152297233679 1.0 0.3125656652313682 3 P56589,P40855 2 +Potassium transport 0.6585703369748845 1.1484671475586703 0.2507757676350879 1.0 0.3576637997418467 6 P05023,P05026,Q96ER9,P55011 4 +Sodium/potassium transport 0.6919617762788125 1.1216430197276837 0.2620142525871234 1.0 0.3676651608883828 3 P05023,P05026 2 +Lipid degradation 0.4746839375243546 1.030051345844848 0.3029859030610395 1.0 0.4118714619736006 15 Q9H6V9,Q8NCC3 2 +Protein transport 0.3214958266500307 0.9989984209429456 0.3177954562185698 1.0 0.4213344850763443 284 Q9Y5J9,O60830,Q9NS69,Q9UL25,Q99595,Q9NR31,Q13432,O60499,O43615,O15126,Q12893,Q969Q5,P0CG08,Q03518,Q15629,Q9H4A6,Q8TEM1,Q96RL7,Q9Y3A6,Q5BJH7,Q9P253,P24390,O14925,Q9NZ43,P49257,Q8N4H5,O75431,O96008,P49755,Q9Y6B6,P41208,Q86Y82,Q7Z3B4,Q13505,Q9UEU0,Q9BVK6,O75381,O15127,Q9UPT5,P51572,Q9P2W9,Q15363,O15504,A6NIH7,Q9BUN8,Q9H0R1,Q2M389,Q9BTX1,Q5JVF3,Q9Y5J6,Q8N5M9,O95070,Q9Y3E0,O60826,Q9HD20,Q03519,O14828 57 +Adaptive immunity 0.4365678119182982 0.7706281969508115 0.4409273429789588 1.0 0.5402912512559074 14 Q07021,P01889,P09429,Q9NZ08,P10321,Q03518,Q03519 7 +Fatty acid metabolism 0.3498627889748152 0.7563594901078499 0.4494336891336972 1.0 0.5468633699948483 53 O95864,P49748,Q9P035,Q9H7Z7,Q8NCC3,P40939,Q6Y1H2,Q9NZ01,P23786,O00767,P51648,Q13011,O15121,Q9UKU0,O15254 15 +Autophagy 0.3380490307024568 0.650673884809391 0.5152570246311694 1.0 0.6211183641019442 38 Q9P253,Q6PHR2,Q9UMX0,P13473,P09429,O14681,O95140,Q969Q5,P53365,Q8IXJ6 10 +Heme biosynthesis 0.4994515171769639 0.6267660665640667 0.5308125899427281 1.0 0.6240634503380722 7 P22830 1 +Stress response 0.32284385298213 0.3846566596252135 0.7004918096009187 1.0 0.7863585475519991 30 O95197 1 +Notch signaling pathway 0.4051791618536847 0.3606571581719126 0.7183557549063375 1.0 0.7968046355759997 8 Q92542,P05067,Q9UBV2 3 +Proline biosynthesis 0.4851039910061893 0.3537379971016471 0.7235352437988962 1.0 0.7968046355759997 3 P54886,Q96C36 2 +Glutathione biosynthesis 0.3560989319842707 0.078626424898442 0.9373297685712862 1.0 0.9900867935620414 3 P48506,P48507 2 +Necrosis 0.3575246132208174 0.0766834035755712 0.9388754076881428 1.0 0.9900867935620414 6 Q96HS1,O60443,Q13546,P04637,O00429 5 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2f5fbcc63d0049c7d3308acac11064d2c51dae98 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Blood coagulation", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Carnitine biosynthesis", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Copper transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Hemostasis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine metabolism", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyridoxine biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sexual differentiation", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF3", "ABHD12", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP5M1", "APEX1", "API5", "APIP", "APOL2", "APOO", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARID4A", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6IP1", "ARL8B", "ARMT1", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATG13", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATRIP", "ATRX", "AUP1", "AURKA", "AURKB", "BABAM1", "BABAM2", "BAG3", "BAG6", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BET1", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOD1L1", "BOP1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRIP1", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C16orf62", "C1QBP", "C2CD5", "CACTIN", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CASP2", "CASP8", "CBL", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC59", "CCDC86", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP250", "CEP290", "CEP55", "CEP97", "CERS1", "CERS2", "CERS5", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLP1", "CLPTM1", "CLPTM1L", "CLSPN", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "COASY", "COG5", "COG7", "COG8", "COMMD2", "COMMD4", "COMMD7", "COMMD8", "COMMD9", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPS7B", "COQ8A", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DEGS1", "DENND4C", "DENR", "DERL1", "DERL2", "DFFA", "DFFB", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLG1", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJB4", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPY30", "DPYSL2", "DRAP1", "DSC3", "DSG2", "DST", "DTX3L", "DTYMK", "DUS2", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAIM", "FAM120B", "FAM162A", "FAM208A", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXL18", "FBXO21", "FBXO22", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1B", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXK1", "FOXRED1", "FPGS", "FRYL", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAN", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGPS1", "GHITM", "GID8", "GINS2", "GINS3", "GINS4", "GM2A", "GMPR2", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRIPAP1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS8", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK2", "HOOK3", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSF1", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKG", "ILF2", "ILF3", "ILVBL", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INPPL1", "INTS13", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IRF2BP1", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCMF1", "KCTD10", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIF11", "KIF1B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5C", "KIFBP", "KIN", "KLC1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRR1", "L3MBTL3", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT2", "LDAH", "LDLR", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIG4", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRPPRC", "LRR1", "LRRC41", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LZTS2", "M6PR", "MACF1", "MAD2L1", "MAEA", "MAGED1", "MAGT1", "MALT1", "MANF", "MAP1S", "MAP9", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED23", "MED24", "MED25", "MED27", "MEN1", "MESD", "METTL1", "METTL3", "MFAP1", "MFN2", "MFSD10", "MFSD14B", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGST2", "MIA3", "MICAL3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MKRN2", "MLEC", "MLLT1", "MMGT1", "MMS19", "MOCS1", "MOCS3", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MRE11", "MRI1", "MRM3", "MRPL58", "MRPS27", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MVB12A", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAE1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCEH1", "NCKAP1", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NEO1", "NES", "NFRKB", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NMD3", "NME1", "NME3", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NR2F1", "NR3C1", "NRDE2", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUBP1", "NUCKS1", "NUDC", "NUDCD1", "NUDT16", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OIP5", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "PA2G4", "PAAF1", "PABPC1", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PANK4", "PANX1", "PAPOLA", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PAWR", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDSS2", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCD3", "PLCG1", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POM121C", "POP1", "POP7", "PPAT", "PPCDC", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPOX", "PPP1CA", "PPP1CB", "PPP1R9B", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKCD", "PRKCZ", "PRKDC", "PRKRA", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", 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"RBPJ", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP4", "RELA", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN3", "RMI1", "RMND1", "RMND5A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPTOR", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RTCB", "RTF1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCAP", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCFD2", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDCCAG3", "SDE2", "SDF4", "SDHA", "SDHB", "SEC13", "SEC14L2", "SEC22B", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP1", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BP4", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHPRH", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAD4", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SON", "SORBS3", "SORT1", "SPATA5", "SPC24", "SPC25", "SPDL1", "SPECC1L", "SPEN", "SPTLC1", "SPTLC2", "SRCAP", "SREK1", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", 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"TRA2B", "TRAF2", "TRAM1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM56", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB2", "TSC2", "TSFM", "TSG101", "TSNAX", "TSR1", "TSR2", "TSR3", "TTC19", "TTC4", "TTF2", "TTLL12", "TTYH3", "TUBB2B", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE3D", "UBE4A", "UBE4B", "UBL5", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFM1", "UFSP2", "UGCG", "UGDH", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USE1", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP32", "USP33", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VPS11", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS52", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WASL", "WBP11", "WDR12", "WDR36", "WDR41", "WDR43", "WDR48", "WDR5", "WDR6", "WDR61", "WDR75", "WDR92", "WIPI2", "WLS", "WRAP53", "WRAP73", "WRN", "WTAP", "XAB2", "XIAP", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YIF1A", "YIF1B", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF1", "YWHAB", "YWHAE", "ZC3H11A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZMYM2", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCC1", "ABCD3", "ABCD4", "ACADVL", "ACBD5", "ACOX3", "ACP6", "ACSL6", "AGPAT5", "AGPS", "ALDH18A1", "ALDH3A2", "ANO6", "AP5M1", "APOL2", "APP", "ARFIP2", "ARL6IP1", "ASAH1", "ASNA1", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V1E1", "ATP7B", "BAG6", "BCAP31", "BCL2L13", "BNIP1", "C1QBP", "CCDC22", "CCDC51", "CDIPT", "CERS1", "CERS2", "CERS5", "CETN2", "CLCC1", "CLCN3", "CLPTM1L", "CNNM3", "CNNM4", "COMT", "COX2", "CPT2", "CYB5B", "CYC1", "CYP51A1", "DAGLB", "DEGS1", "DERL1", "DHCR24", "DHCR7", "DNM1L", "ECH1", "EI24", "ERAP1", "ERG28", "ERGIC1", "ERGIC3", "ETFDH", "EXOC7", "FADS2", "FAM162A", "FDFT1", "FECH", "FOXRED1", "GBA", "GCLC", "GCLM", "GHITM", "GM2A", "GOLIM4", "GOLPH3", "GOLT1B", "GPAA1", "GPAM", 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"SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC44A1", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A6", "STARD3", "STX10", "STX12", "STX18", "STX4", "STX8", "SULT1A4", "SV2A", "TAMM41", "TAP1", "TAP2", "TECR", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM8B", "TM7SF2", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED9", "TMEM115", "TMX1", "TMX4", "TOMM22", "TOMM40", "TOMM5", "TP53", "TRAM1", "TTC19", "TTYH3", "UBQLN1", "UGCG", "ULK3", "UNC119", "UNC119B", "UQCR10", "UQCRB", "UQCRC2", "UQCRQ", "USE1", "VDAC1", "VDAC2", "VDAC3", "VPS13A", "VPS18", "VTI1B", "WASHC4", "YIF1A", "YIF1B", "YIPF5"]} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/idx2term.json b/protein_atlas_disease_involvement/advanced/idx2term.json new file mode 100644 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--- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 115, + "title": "Average number of proteins per term", + "value": 24.469565217391306 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..edf49c417871eab537bdbbb967aeb61e89250848 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..70b69d8a74d79cc4f0dad29ba180c950607b8b5a --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,41 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Primary mitochondrial disease 0.524974445486517 3.388058108271799 0.0007038935008698 0.0777844110593868 0.007358886600003 101 Q9NPL8,Q8NI60,Q99797,Q9BQP7,Q9UGM6,Q9BUB7,Q53H12,P13073,O00483,O75489,P12235,Q6P4A7,O14949,P20674,Q96CU9,Q07021,O43676,Q9Y6M9,P08574,Q9P032,P14927,Q70HW3,Q8N183,Q96I36,Q9NWS8,Q5XKP0,O75880,Q9Y2R0,Q9UMS0,Q6DKK2,P82650,Q86Y39,P82930,Q9Y2Z2,P03886,O75380,Q16795,O43819,Q9Y2R9,P00403,O60313,P22695,Q9P0J0,Q8TB37,Q9Y276,Q9UBX3,Q9Y3D9,Q9NX14,O75251,Q96IX5,Q9Y375,O75306 52 +Gaucher disease 0.9719022197246414 2.753319465792118 0.0058994297560994 0.493607650367909 0.0452289614634292 2 P04062 1 +Niemann-Pick disease 0.8654116324810276 2.2933569803799125 0.0218274612246458 0.9209724313041022 0.120411143692211 2 O15118 1 +Neuronal ceroid lipofuscinosis 0.8990722518976604 1.9421944957417336 0.0521135591896575 0.997876874086652 0.2605677959482877 4 O75503,P50897,O14773 3 +Congenital disorder of glycosylation 0.5480007991460746 1.7414265050350934 0.0816088455761598 0.9999440004426424 0.331300450311084 20 Q8N511,Q2TAA5,P46977,Q9BT22,Q9HC07,P51571,Q8TCJ2,O75352 8 +Ichthyosis 0.6537624247594003 1.7207556553100904 0.0852951723646899 0.9999647376144536 0.331300450311084 10 P04062 1 +Ehlers-Danlos syndrome 0.8413844032967697 1.7141787700133777 0.0864958986627821 0.999969681502404 0.331300450311084 4 Q8NCH0 1 +Maple syrup urine disease 0.715650463613366 1.611854540665201 0.1069935964458113 0.999997770148662 0.3519550153849039 2 P12694 1 +Emery-Dreifuss muscular dystrophy 0.7644127470776076 1.5973970833334166 0.1101772222074481 0.9999985212163236 0.3519550153849039 6 P50402,P02545 2 +Cone-rod dystrophy 0.7901864431907437 1.52382007714396 0.1275536627725255 0.9999998469077432 0.3788072094992326 3 Q13432 1 +Mucopolysaccharidosis 0.7374049718769268 1.4836194802231704 0.1379098984358044 0.999999961224649 0.3898919537797126 6 P08236,P54802,P16278 3 +FDA approved drug targets 0.3531695322724171 1.4166411050583023 0.1565878841976167 0.9999999968769346 0.4215641351879339 136 Q16739,Q8N0U8,Q16850,P49721,P49354,P23786,Q99720,P12235,P04035,P05141,P21964,Q16134,Q96ER9,P00374,O95864,P16615,P03886,P10253,Q96QD8,P05023,Q13423,Q14534,Q7L0J3,P12236,P14735,P05067,P12814,P00813,P38435 29 +Gangliosidosis 0.7410077951755247 1.4130931781107547 0.1576283288094013 0.999999997290235 0.4215641351879339 5 P07602,P17900 2 +Parkinson disease 0.5912607654462637 1.346791167635733 0.1780475001434256 0.9999999998387972 0.4508952179696823 9 P04062 1 +Peroxisome biogenesis disorder 0.7483834692156237 1.339653298772473 0.1803580871878729 0.9999999998833786 0.4508952179696823 4 P56589,P40855,O75381 3 +Zellweger syndrome 0.7483834692156237 1.339653298772473 0.1803580871878729 0.9999999998833786 0.4508952179696823 4 P56589,P40855,O75381 3 +Rhizomelic chondrodysplasia punctata 0.7397414277684127 1.3172316370401551 0.1877609922865755 0.9999999999589188 0.4594151938926847 3 P50542,O00116 2 +Proto-oncogene 0.4042017075318526 1.2827556885717823 0.1995776828689177 0.9999999999923844 0.4760620285119127 47 Q8WY22,Q06136,P49589 3 +Parkinsonism 0.556085245551122 1.273491122290337 0.2028438208442062 0.9999999999952413 0.4760620285119127 11 P04062 1 +Cataract 0.4304759396937807 1.2284113536978885 0.2192925879183165 0.9999999999995672 0.5022758283947677 29 P08670,Q9UG56,Q8WVX9,Q9H078,O76024,Q15800,Q53H12,O00116,P48449 9 +Epilepsy 0.381687582518803 1.2192523953299976 0.2227484108533317 0.9999999999997402 0.5022758283947677 70 P05023,Q14108,P22466,Q03252,P16615,Q96T60,O75503,O14874,Q9H078,Q8TAD8,P27544,P03886,O14773,Q13510,Q9H490,Q92643,Q96RL7,Q92581 18 +Craniosynostosis 0.6998751628833155 1.143060521523051 0.2530134639169086 0.9999999999999972 0.5388249694526757 4 P16435 1 +Progressive external ophthalmoplegia 0.6747971120983578 1.041886970101073 0.2974640858289334 1.0 0.5897994805228853 4 P12235,Q9BQP7 2 +Amyloidosis 0.6411155696366837 0.9976768572344322 0.3184360788521698 1.0 0.5901001784554756 5 P03886,Q9Y287 2 +Diabetes mellitus 0.4942181157747319 0.991955778918834 0.321219097503036 1.0 0.5901001784554756 12 O76024,P03886 2 +Neurodegeneration 0.3213431774566356 0.9773345018061088 0.3284035775752212 1.0 0.5901001784554756 147 Q8NI60,Q14108,Q10713,Q03252,Q15041,Q96A57,O75477,Q99720,Q96RL7,Q8N766,O75503,Q8TB36,P50897,P04062,P03886,O14773,Q13510,P54802,O60313,P05023,Q96T60,Q8NHS3,Q9Y320,P35637,P27544,P02545,P05067,O15269,Q8IXJ6,Q8IV08,Q9Y287 31 +Autism 0.6051570448548902 0.9219927446559444 0.356532360142938 1.0 0.6029591384770274 6 O14874 1 +Cardiomyopathy 0.398337770297598 0.8867881366547374 0.3751929758761871 1.0 0.6155870515289567 26 P50402,P49748,P02545,P09493,Q53H12,Q9NX14,O60313,O43819,P12235,Q9BTV4 10 +Congenital muscular dystrophy 0.5331346983878318 0.773072653642054 0.4394793841025985 1.0 0.6613604773672892 7 O43505,P02545 2 +Allergen 0.5066029783647091 0.6553283549364353 0.512256368504068 1.0 0.7325651563060217 2 O43290 1 +Hypotrichosis 0.4712359618327248 0.649553503814547 0.515980675311198 1.0 0.7325651563060217 8 Q8IWS0,Q14574,P48449 3 +Limb-girdle muscular dystrophy 0.4436552900321274 0.6056802194468125 0.544727121617409 1.0 0.7457573688809765 9 Q5JTV8,P02545 2 +Premature ovarian failure 0.4900252880022346 0.5868427099187249 0.5573093493538299 1.0 0.750522237595423 2 Q5JTZ9 1 +Osteogenesis imperfecta 0.4264590150633915 0.4493893151136618 0.6531508377922655 1.0 0.8336269824226354 8 P07237,Q96AY3,P50454,Q32P28,Q14696 5 +Dystroglycanopathy 0.4979226464664068 0.4403927766511409 0.6596526556561724 1.0 0.8336269824226354 5 O43505 1 +Alzheimer disease 0.4747409886739631 0.4062036867871262 0.6845929453978616 1.0 0.8413131013218959 6 P03886 1 +Dystonia 0.4735515070668085 0.4020027352699656 0.6876820132544192 1.0 0.8413131013218959 6 P51572 1 +Hereditary spastic paraplegia 0.3516650205770422 0.3181743546933826 0.7503526847217161 1.0 0.8805159055407894 15 Q15041,P54886,Q8IY17,Q9H0B6,Q12768,O75477 6 +Lissencephaly 0.359111591314975 0.2659467628102185 0.7902802099602653 1.0 0.9088222414543052 11 O43505,Q6ZXV5 2 +Congenital myasthenic syndrome 0.4221409416660256 0.178597360056233 0.8582538675314562 1.0 0.9676391643737006 4 P53007 1 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..01005993e3835060bc4a9a30a59da5d170661129 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Brugada syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pseudohermaphroditism", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD4", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACVR1B", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKR1B1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP1S1", "AP1S2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARPC1B", "ARSA", "ASAH1", "ASCC1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG13", "ATG5", "ATIC", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6AP1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP7B", "ATRX", "ATXN10", "AURKA", "AURKB", "B3GALT6", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCKDHA", "BCKDK", "BCLAF1", "BCOR", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD3", "BRI3BP", "BRIP1", "BUB1B", "C12orf57", "C19orf70", "C1QBP", "C21orf59", "CAD", "CADM1", "CALR", "CAMK2G", "CANX", "CAPN1", "CARM1", "CARS", "CASK", "CASP2", "CASP8", "CAST", "CBFB", "CBL", "CBX2", "CC2D1A", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC8", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT5", "CD320", "CDC16", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKAL1", "CEP250", "CEP290", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD3", "CHD4", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLIP1", "CLN5", "CLP1", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "COA3", "COA7", "COASY", "COG5", "COG7", "COG8", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COX14", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTDP1", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DBN1", "DBT", "DCAF8", "DCK", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEGS1", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIS3", "DIS3L2", "DKC1", "DLD", "DLG3", "DLST", "DNA2", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DSC3", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "EPB41", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXOC6B", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EYA4", "EZR", "FADS2", "FAF1", "FAH", "FAM120A", "FAM3C", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FBXO7", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GAL", "GALK1", "GALM", "GALNT2", "GAN", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GGPS1", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI3", "GNAO1", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPHN", "GPI", "GPRASP2", "GRB2", "GSDME", "GSK3A", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2H1", "GTF2I", "GTPBP3", "GUSB", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGCR", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOOK3", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IGBP1", "IGF2R", "IGHMBP2", "IKBKG", "ILF3", "ILK", "IMPDH1", "IMPDH2", "INF2", "INPPL1", "INTS1", "INTS8", "IPO7", "IQCB1", "IRF2BPL", "IRS4", "ISCA2", "ITGA6", "ITGB1", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KLC2", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LGMN", "LIG4", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPPRC", "LRSAM1", "LSS", "LTA4H", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED1", "MAGED2", "MAGT1", "MALT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MARS", "MARS2", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MED1", "MED12", "MED17", "MED23", "MED25", "MEN1", "MESD", "MFN2", "MFSD8", "MGME1", "MICU1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MLLT1", "MMAB", "MOCS1", "MOGS", "MORC2", "MPDU1", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTMR14", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MVK", "MYH10", "MYH14", "MYH9", "MYO5A", "MYO6", "NAA10", "NAA15", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCKIPSD", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA6", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NEO1", "NF1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NNT", "NONO", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NR2F1", "NR3C1", "NRP1", "NSD1", "NSD2", "NSDHL", "NSMCE3", "NSUN2", "NSUN3", "NSUN5", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OSGEP", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B2", "PANX1", "PAPSS2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDAP1", "PDCD4", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDSS2", "PDXK", "PEPD", "PEX14", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PI4KA", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIN1", "PINX1", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRKRA", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PTDSS1", "PTPN11", "PTPN13", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "RAB10", "RAB18", "RAB23", "RAB3GAP2", "RAB7A", "RAB8A", "RABEP1", "RAC1", "RAD21", "RAD23A", "RAD23B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBL1", "RBM10", "RBM12", "RBM15", "RBM28", "RBMX", "RBPJ", "RDH11", "RDX", "RELA", "REPS1", "RFC1", "RFC2", "RFK", "RHEB", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "ROCK1", "ROCK2", "RP2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS26", "RPS28", "RPS29", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RRM1", "RRM2", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SART1", "SASS6", "SBDS", "SCARB2", "SCO1", "SCO2", "SCRIB", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC31A", "SEC61A1", "SEC63", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SGSH", "SH3GL1", "SHOC2", "SIGMAR1", "SIN3A", "SIRT2", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC38A2", "SLC3A2", "SLC44A1", "SLC9A3R1", "SLC9A6", "SMAD4", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SNAP29", "SND1", "SNIP1", "SNRNP200", "SNRPE", "SNX3", "SOD2", "SON", "SORD", "SPART", "SPATA5", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRP54", "SRP72", "SRSF2", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD3", "STAT1", "STAT3", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "SUCLA2", "SUCLG1", "SUZ12", "SV2A", "SYNE1", "SYNE2", "TAF2", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D24", "TBC1D4", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCF20", "TCOF1", "TDP2", "TDRD7", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THG1L", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM50", "TIMMDC1", "TJP2", "TK1", "TKFC", "TKT", "TLK2", "TMCO1", "TMEM165", "TMEM199", "TMEM230", "TMEM43", "TMEM70", "TMF1", "TMLHE", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOM1", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPRKB", "TPX2", "TRAF2", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMU", "TRRAP", "TSC2", "TSFM", "TSG101", "TSR2", "TTC19", "TTI2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP4", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBE2T", "UBE3A", "UBQLN4", "UBR5", "UBTF", "UFM1", "UFSP2", "UGCG", "UGDH", "UGP2", "UMPS", "UNC119", "UNG", "UPF3B", "UQCRB", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP8", "USP9X", "UTP4", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS11", "VPS13A", "VPS13C", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP2", "WDR1", "WDR26", "WDR36", "WDR5", "WFS1", "WIPI2", "WNK1", "WRAP53", "WRN", "XIAP", "XPNPEP3", "XPO1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "YARS", "YARS2", "YBX1", "YES1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZCCHC8", "ZMPSTE24", "ZMYM2"], "leading_proteins": ["AARS2", "ACADVL", "ACTN1", "ADA", "AGK", "AGPS", "ALDH18A1", "ALG1", "ALG11", "APP", "ARL6IP1", "ASAH1", "ATP1A1", "ATP2A2", "B4GAT1", "BCAP31", "BCKDHA", "BCKDK", "BCS1L", "BRI3BP", "C19orf70", "C1QBP", "CARS", "CCDC51", "CERS1", "CHST14", "CLN5", "CLPB", "COA3", "COMT", "COQ8A", "COX14", "COX2", "COX4I1", "COX5A", "CPT2", "CYC1", "CYP51A1", "DHFR", "DSC3", "EMC1", "EMD", "ERLIN1", "ETFDH", "FADS2", "FAR1", "FKBP10", "FNTA", "FOXRED1", "FUS", "GAA", "GAL", "GBA", "GDAP1", "GGCX", "GLB1", "GM2A", "GUSB", "HMGCR", "IDE", "ITM2B", "KDSR", "KLC2", "LMNA", "LMNB2", "LSS", "MESD", "MFSD8", "MGME1", "MIPEP", "MPDU1", "MRPS22", "MRPS23", "MRPS34", "MRPS7", "MSMO1", "MTO1", "NAGLU", "ND1", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NFU1", "NNT", "NPC1", "NUBPL", "OPA1", "P3H1", "P4HB", "PEX14", "PEX19", "PEX3", "PEX5", "PHF6", "PIGK", "PIGU", "PISD", "PLD3", "PMPCA", "PNKP", "PNPLA6", "POR", "PPT1", "PSAP", "PSMB2", "RMND1", "SART1", "SCARB2", "SCO1", "SCO2", "SERPINH1", "SFXN4", "SIGMAR1", "SIRT2", "SLC25A1", "SLC25A10", "SLC25A26", "SLC25A4", "SLC25A5", "SLC25A6", "SLC38A2", "SLC9A6", "SNIP1", "SPTLC1", "SQLE", "SSR4", "STT3A", "STT3B", "SV2A", "TIMMDC1", "TMEM165", "TMEM199", "TMEM230", "TMEM43", "TMEM70", "TMTC3", "TMX2", "TOR1AIP1", "TPM1", "TPP1", "TTC19", "UGCG", "UNC119", "UQCRB", "UQCRC2", 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a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..938804a1990040a71acc3ec41e928cc29f18e40c --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,8 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 18 45 3.4002752185051253 0.0006731805895663 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.0292740292610029 0.005639897207451 0.0867264608587171 0.0361015479736687 0.0565317597261831 +Oxidoreductase 35 177 2.616346696468848 0.0088876264406112 36.64563106796116 165.7621359223301 0.5091071251362119 0.5527126631147542 14.160338956360992 12.210799107974529 1.1772957028589783 0.3900527505954884 3.4813443761866575e-05 0.0220602301547892 0.0004418725815228 8.699473466917048e-07 1.040434962319101e-07 +Acyltransferase 9 34 2.5690393007017644 0.0101980891058264 8.567961165048544 34.39320388349515 0.3097294578230991 0.5297298584890537 3.96559753433415 4.2944706407944055 0.9755344857013418 0.3286789480056776 0.0971167211311973 0.3743474102701529 0.2460090370927736 0.0920920135562724 0.0230219191250441 +Glycosyltransferase 9 37 2.241414689410625 0.024999225880588 8.383495145631068 33.63106796116505 0.9005425082235603 0.4380439374186179 3.633517034002208 4.6602851932859135 0.9766631781348049 0.3531801259598526 0.6124827027919243 1.0 0.6777230475683339 0.007332976666975 0.0600596606487492 +Host cell receptor for virus entry 4 16 2.144896628430777 0.0319611128760211 4.509708737864078 15.157766990291265 0.7214109752050332 0.2527966464979699 2.499010078306418 1.9009100692398744 1.5211756979359785 0.2791170769282048 0.0355040413058726 0.0159273139692264 0.0592322030833591 0.0171039247471448 0.0494824412948022 +Translocase 11 28 2.1033983402655845 0.0354309634180509 8.031553398058252 23.23543689320388 0.8266305625937611 0.3429767730570308 3.903132239147793 3.2553774114037415 1.2917497354360188 0.3272657999875639 0.0197691529689287 1.0 0.1094034461657393 0.0005144645132141 0.0021062451144682 +Carboxypeptidase 3 6 1.9903492749650489 0.046552473505995 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 0.0268439946301445 1.0 0.0085055091795532 0.004864195908138 0.0047081007231922 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..33f42a1d16714ea9d41d215d482218bf15bb7c83 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 99, + "title": "Average number of proteins per term", + "value": 41.888888888888886 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fa11a4ed90f787ac7157d27f61c915c7c1d379b6 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6a4c12616efa78c2b3e548a08cc9085f7c61d07c --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,25 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.6533749348058357 3.4002752185051253 0.0006731805895663 0.0644936265951103 0.009520696909581 45 P35613,Q14108,P36896,Q9NS69,P11279,P24390,Q9Y5M8,O00264,P10586,O15118,Q99623,O15173,Q14739,P55899,Q8WTV0,Q99720,P30825,O15031 18 +Oxidoreductase 0.4125547306846291 2.616346696468848 0.0088876264406112 0.5867937187882419 0.0557413884793565 177 P30519,Q8N0U8,Q16850,P13073,Q6UW02,Q06136,Q9UBM7,Q6NUM9,Q96LJ7,Q9NRG7,Q53GQ0,Q16134,Q9NZ01,P21912,Q15392,P00374,O76062,O15121,Q9UHG3,Q8N4Q0,O95864,P09601,O00625,Q6IAN0,O00767,P51648,P16435,P49748,O95881,Q8TED1,Q99536,Q14534,Q15800,Q14739,P40939 35 +Acyltransferase 0.5674199177941197 2.5690393007017644 0.0101980891058264 0.6375229590944691 0.0557413884793565 34 Q8NF37,Q5W0Z9,Q9HCL2,Q9NUQ2,Q8NCC3,Q92604,Q8IUH4,Q96N66,P23786 9 +Glycosyltransferase 0.5167365968742816 2.241414689410625 0.024999225880588 0.91843739446757 0.112496516462646 37 Q8N4A0,Q2TAA5,Q16739,P46977,Q13126,P04062,P43490,Q10472,Q9BT22 9 +Host cell receptor for virus entry 0.6547893502313568 2.144896628430777 0.0319611128760211 0.95987753858737 0.1375717467272212 16 O15118,P35613,Q14108,Q8WTV0 4 +Translocase 0.5497974554886913 2.1033983402655845 0.0354309634180509 0.9718810988382012 0.1415999816567181 28 P05023,Q13423,P16615,P06576,P08574,P35670,P03886,Q9HD20,P08183,Q03519,P00403 11 +Porin 0.9156592634242284 2.006960016850448 0.0447539204836975 0.9892499339899988 0.1530578750175765 4 P45880,Q9Y277,P21796 3 +Carboxypeptidase 0.8595207268055673 1.9903492749650489 0.046552473505995 0.9910796304995892 0.1530578750175765 6 Q9H3G5,P42785,Q9HB40 3 +Protease 0.394487973659018 1.7409309212515094 0.0816956878423686 0.9997833913758806 0.2045296600818001 91 P10619,P09960,Q8TCT8,P42892,O75844,Q7Z2K6,Q9H3G5,P55786,O14773,Q92643,Q16740,P67812,P42785,Q9HB40 14 +Monooxygenase 0.8382230941166422 1.701569415215925 0.0888361149850243 0.999899987733494 0.2045296600818001 4 Q16850 1 +Metalloprotease 0.4851366056288591 1.582850622663191 0.1134555153399121 0.9999933571766922 0.2441760004054631 27 P09960,P55786,O75844,Q7Z2K6 4 +Ion channel 0.5518944047843503 1.374435130040621 0.1693066362640443 0.9999999894164014 0.3099041370036798 13 Q9C0H2,P0CG08,Q96ER9,Q96S66,Q9UM00 5 +Serine protease 0.5837949738106638 1.1893341022439632 0.2343082208705653 0.9999999999966784 0.4069563836172977 8 Q16740 1 +Calcium channel 0.7009555930297962 1.1583608679205928 0.2467168014493583 0.999999999999341 0.4139824295506183 3 Q9UM00,Q96RD7 2 +Ribosomal protein 0.321184437970644 0.9211134492324692 0.3569911992039125 1.0 0.5350674080443472 125 Q96GC5,Q02878,P39023,P27635,P61927,Q96A35,Q9NWU5,P84098,P18124,Q9BYD1,P62266,P62910,P46779,P50914,P62424,P82933,Q9BYD2,P82663,P46776,P49406,P47914,P40429,P61513,Q13084,P46778,P62917,Q9Y3B7,Q5T653,P82650,P82930,Q07020,P61313,P83881,Q9Y2R9,P36578,Q9HD33,Q7Z7H8,Q9BYN8,Q9Y3U8,P82912,Q02543,P18077,Q92665,P62241,Q9Y3D9,P62847,P62854 47 +Integrin 0.5436920483281747 0.8157916337858676 0.4146193190351832 1.0 0.559784498507438 2 P23229 1 +Guanine-nucleotide releasing factor 0.3937453212149149 0.7002178353491126 0.483791274929525 1.0 0.6140427720259356 20 Q02818 1 +Heparin-binding 0.4371565329358411 0.4957581386605175 0.6200650627421331 1.0 0.7469032357755837 8 P05067,P47914,P10586 3 +Chloride channel 0.4992877818207706 0.4451487001152223 0.6562122967040598 1.0 0.7733930639726418 5 Q9C0H2,Q96S66 2 +Lyase 0.3031910887546618 0.2949091052691795 0.7680633161320678 1.0 0.8649242948997502 48 Q9P035,Q9UG56,A1L0T0,Q99735,Q8NBZ7,Q6Y1H2,P53701,P12956,P22830,P40939,O95470,P38435 12 +Glycosidase 0.3261266398613364 0.2548464213241444 0.7988417196583115 1.0 0.8807230800766572 19 P04062,P04066,P10253,P16278,Q13724,P54802,P08236 7 +Endonuclease 0.3257222349611944 0.2524964657894797 0.8006573455242338 1.0 0.8807230800766572 19 O94919 1 +Ribonucleoprotein 0.2661609797312979 0.1214678658121676 0.9033204655755492 1.0 0.9827332537580148 192 P22087,Q96GC5,P55795,P52272,Q02878,P52597,P39023,P27635,P38159,Q14103,Q9UHX1,P61927,Q96A35,Q9NWU5,Q96G21,P84098,P31943,P18124,Q9BYD1,P62266,P62910,P46779,P50914,P62424,P82933,Q9BYD2,P82663,P46776,P49406,P47914,P40429,P61513,Q13084,P46778,O60506,P62917,P22626,Q9Y3B7,Q5T653,P82650,P82930,Q07020,Q13151,P61313,P62310,P83881,Q9Y2R9,P36578,Q9HD33,Q7Z7H8,Q9BYN8,O95478,Q9Y3U8,P82912,P62241,P18077,Q92665,Q02543,P31942,Q9Y3D9,P62847,P62854 62 +Muscle protein 0.3136650152722169 0.023877131187333 0.9809506157507756 1.0 1.0 7 P09493,P46020 2 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fe5a9b7254964537dc4aa2dacdd07dd5532c54fe --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "IgG-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Neuropeptide", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AACS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB6", "ABCC1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "AMPD2", "ANKHD1", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APIP", "APLP2", "APP", "APRT", "AQR", "ARFGAP1", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARID4A", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATG3", "ATG4B", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP7B", "ATRX", "AURKA", "AURKB", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAZ1B", "BCAT2", "BCKDHA", "BCKDK", "BCLAF1", "BCOR", "BCR", "BCS1L", "BDH2", "BIRC6", "BLM", "BLMH", "BLVRA", "BPNT1", "BPTF", "BRAP", "BRCA1", "BRD1", "BRD2", "BRD3", "BRIP1", "BRMS1L", "BRPF3", "BSG", "BTF3", "BUB1B", "BZW1", "BZW2", "C12orf43", "CACTIN", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP8", "CAST", "CBL", "CBR1", "CBX2", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC25C", "CDC34", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CEP290", "CEP55", "CEP97", "CERS1", "CERS2", "CERS5", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHKA", "CHML", "CHMP1A", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLP1", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSPN", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT7", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPS5", "COQ8A", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRYZ", "CS", "CSDE1", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND4C", "DENR", "DEPDC1B", "DFFB", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIMT1", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DRAP1", "DRG1", "DRG2", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERP44", "ESD", "ESPL1", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "F11R", "FADS2", "FAH", "FAHD1", "FAHD2A", "FAM120A", "FAM120B", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLYWCH1", "FMR1", "FN3KRP", "FNTA", "FOXK1", "FOXRED1", "FPGS", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDI1", "GDI2", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C5", "GUSB", "GXYLT1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INPPL1", "INTS11", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRS4", "ISG20L2", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITPA", "IVD", "JMJD6", "KANSL3", "KARS", "KAT7", "KCMF1", "KCTD15", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIN", "KLC1", "KLC2", "KRR1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD3", "LEO1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIG4", "LIMA1", "LIN28B", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED1", "MAGED2", "MALT1", "MAN2A1", "MAN2B1", "MANF", "MAP1S", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MATR3", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL7B", "MFN1", "MFN2", "MGEA5", "MGME1", "MGST2", "MGST3", "MICAL3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MKRN2", "MLLT1", "MMAB", "MMS19", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPI", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MVK", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCBP2", "NCEH1", "NCL", "NCOA5", "ND1", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NF1", "NFRKB", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME3", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA1", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NR2F1", "NR3C1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN3", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OTUD7B", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PAPSS2", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM7", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PHKB", "PHPT1", "PI4K2A", "PI4KA", "PI4KB", "PIGG", "PIGK", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCD3", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR2H", "POLR3A", "POLR3C", "POLRMT", "PON2", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R9B", "PPP3CA", "PPP4C", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKCD", "PRKCZ", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRSL1", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAD51AP1", "RALA", "RALGAPB", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RELA", "RETSAT", "REXO4", "RFC1", "RFC3", "RFK", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK2", "RIOX2", "RIPK1", "RMND5A", "RNASEH2A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRM1", "RRM2", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SCAF1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC14L2", "SEC61A1", "SEC63", "SENP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGPL1", "SGSH", "SGTA", "SHMT1", "SHMT2", "SHPRH", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMG1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SOD2", "SON", "SORD", "SORT1", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STK26", "STMN1", "STRBP", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SULT1A4", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE1", "SYNE2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D24", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TDP2", "TDRD7", "TDRKH", "TECR", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "TGS1", "THAP11", "THG1L", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THTPA", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TLK2", "TM7SF2", "TMCO1", "TMEM109", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM56", "TRIO", "TRIP12", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSFM", "TSN", "TSNAX", "TSR3", "TSTA3", "TTF2", "TTK", "TTYH3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE3D", "UBE4A", "UBE4B", "UBLCP1", "UBP1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "UROD", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP32", "USP33", "USP34", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP3", "UTRN", "UXS1", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VRK1", "VRK2", "WARS", "WARS2", "WASF2", "WASL", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR48", "WDR5", "WLS", "WNK1", "WRAP53", "WRN", "WTAP", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "ZADH2", "ZC3H14", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZDHHC13", "ZDHHC20", "ZFR", "ZMPSTE24", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF638", "ZRANB2"], "leading_proteins": ["ABCB1", "ACADVL", "ACVR1B", "AGPAT5", "ALDH3A2", "ALG1", "ALG11", "APP", "ATP13A1", "ATP1A1", "ATP2A2", "ATP5B", "ATP7B", "BSG", "CCDC51", "CLCC1", "CLPP", "COX2", "COX4I1", "CPT2", "CPVL", "CTSA", "CYC1", "CYP20A1", "CYP51A1", "DEGS1", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7B", "ECE1", "ENDOD1", "ERMP1", "ETFDH", "FADS2", "FBL", "FCGRT", "FECH", "FUCA1", "GAA", "GALNT1", "GALNT4", "GBA", "GGCX", "GLB1", "GPAM", "GPR89B", "GPX8", "GUSB", "HACD2", "HACD3", "HADHA", "HCCS", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA2B1", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPM", "HSD17B12", "ILVBL", "IMP4", "ITGA6", "KDELR1", "KDSR", "LAMP1", "LBR", "LPCAT1", "LPGAT1", "LSM3", "LTA4H", "MBOAT7", "MGST2", "MOGS", "MRPL10", "MRPL11", "MRPL13", "MRPL19", "MRPL2", "MRPL22", "MRPL24", "MRPL28", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS31", "MRPS34", "MRPS7", "MRPS9", "MSMO1", "MTAP", "NAGLU", "NAMPT", "ND1", "NNT", "NPC1", "NPEPPS", "NSA2", "NUCB1", "PANX1", "PCYOX1", "PGRMC1", "PGRMC2", "PHB2", "PHKA1", "PIGK", "PIR", "PISD", "PLA2G15", "PLXNB2", "POR", "PRCP", "PTPRF", "PUF60", "RBMX", "RETSAT", "RPL10", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL32", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL8", "RPS23", "RPS24", "RPS26", "RPS8", "SCARB1", "SCARB2", "SCD", "SCPEP1", "SDHB", "SDR39U1", "SEC11A", "SGPL1", "SIGMAR1", "SLC7A1", "SPPL2A", "SQLE", "SRPRB", "STT3A", "SYNCRIP", "TAP2", "TECR", "TM7SF2", "TMCO1", "TOMM22", "TPM1", "TPP1", "TTYH3", "TXNDC12", "UGCG", "UXS1", "VAT1", "VDAC1", "VDAC2", "VDAC3", "VKORC1L1", "XRCC6", "ZADH2", "ZDHHC13", "ZDHHC20", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a4d19adb921a463bd855ce2a6620c0ea70e1524f --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins", "1": "Transporters", "2": "Metabolic proteins", "3": "Predicted secreted proteins"} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/plot_0.png b/protein_atlas_protein_class/advanced/plot_0.png new file mode 100644 index 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overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 307 641 8.897317885584593 5.721245783447145e-19 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 1.341339873285857e-47 1.5954939161399499e-12 7.857434744185941e-25 4.295782033185834e-58 1.0848733982401827e-77 +Transporters 151 412 6.1933480671043375 5.889946264314632e-10 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 1.2678386986092452e-13 0.002875585238758 1.306935525443071e-05 4.960537560060007e-21 7.955355321093568e-31 +Metabolic proteins 152 977 2.157754670023679 0.0309469109365969 167.96116504854368 885.0898058252427 0.3517504365488901 0.4992811695371688 49.08590099318301 81.73901275864796 1.4937513760737942 0.4046478208580187 1.6208550804479658e-08 0.0301146878226825 9.680578164972484e-05 1.0431982562969768e-11 2.1958319778434636e-11 +Predicted secreted proteins 15 55 2.0622387015913217 0.0391850157664883 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 0.1836672081297603 0.7162122803216393 0.0133509226901403 0.1900905157248673 0.5327833822814634 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0d3fdd2f3df00452714cc9e559c0fe3d1e7319ff --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 21, + "title": "Average number of proteins per term", + "value": 537.4285714285714 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b0bb40e1d17626ae4d285623d32ee3b774ec9407 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..84e0be9ce5f3e46f25a66caeffafcfdb439ad6ab --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,12 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.7176118020411734 8.897317885584593 5.721245783447145e-19 3.3014616145239007e-17 1.1004872048413004e-17 641 Q9BQE5,Q14108,O60830,Q9NS69,O43169,Q99595,Q8N4V1,Q9H061,Q9H6V9,P30519,Q8N0U8,Q16850,O75964,Q15629,Q6UW02,Q06136,P37268,Q8WTV0,Q99720,P67812,Q8WY22,Q8N511,O95197,P24390,O60637,Q8N8L6,O43676,P43307,Q9Y282,Q8NCC3,Q567V2,Q9UDW1,O95772,Q70HW3,Q8WVI0,Q9NX00,Q9UDX5,Q15392,O76062,P08183,Q14849,Q13505,Q8NF37,P09601,Q9C0H2,Q9Y2R0,Q5BJF2,Q96A26,Q5T9L3,O00461,O43772,Q9H1E5,Q5VW38,Q86Y39,Q969V3,Q9BSK2,Q9HD45,Q8IXM6,Q9P2W9,P03886,P51648,Q86YN1,O94919,O60725,Q9BUN8,Q96QD8,O75071,Q8N2A8,Q9NR77,Q9BTX1,Q9NPR9,Q8TB61,P51812,Q3SXM5,Q9HC07,O75844,Q8N5M9,Q9NQC3,Q7Z2K6,O95070,Q15800,Q9UBX3,O15173,Q14739,Q9Y6C9,Q9HD20,P27105,Q96N66,O95470,P38435,Q8NBN3,Q86XL3,Q9NZJ7,O43657,P36896,Q15041,Q16739,Q96CP7,Q9HC21,Q86VD7,O60499,Q8TAA9,Q96A57,P35670,Q5SR56,O15118,Q96KA5,Q96G23,Q9H4I3,P13073,Q8IUH4,Q8IWB1,Q96KC8,Q9UKU0,Q5H8A4,Q96SK2,Q5BJH7,Q8NCH0,O96005,O14925,Q9UG56,Q8TCT8,Q53GQ0,Q8IXU6,Q6UW68,Q10472,O43760,Q07065,Q96A33,Q99805,Q9NX40,Q14728,O95864,P35613,Q9P035,P16615,Q5SNT2,Q9H3N1,O15127,O00264,Q92604,Q9Y6M7,Q6Y1H2,Q8TBA6,O43292,Q15070,Q15363,Q8IZA0,Q9BT22,Q9UM00,Q9P0S9,P16435,P00403,Q13423,Q8NC54,P57088,P46977,P42892,Q9P0J0,O14681,Q14534,Q6ZXV5,P12236,P27544,Q8NE00,Q5W0Z9,Q86UE4,Q92643,Q8IV08,Q9Y287,Q9BXK5,Q15005,Q9Y5M8,P13473,Q93050,Q8WVC6,Q07820,O76024,Q9BUB7,P10321,Q12846,Q9H490,Q9UBM7,Q6P4A7,Q6NUM9,P50402,P11279,P27824,P08574,Q16134,Q08722,Q70UQ0,Q8TB36,Q96ER9,Q9NZ01,O95202,Q6P4Q7,Q9BU23,O15121,O95168,Q12770,Q9BTV4,P30825,Q6NTF9,Q9HCL2,Q9NUQ2,Q2TAA5,Q9H3K2,O95563,O15400,Q6IAN0,Q7RTS9,Q96M27,O00767,Q9UH99,Q9UBU6,Q5SWX8,P24539,Q8NC44,P05023,Q5VV42,O43808,Q12981,Q8NHS3,Q99735,Q9Y320,Q7L0J3,Q9Y3E0,Q5SQN1,O15258,Q86Y07,Q96IX5,Q9NPL8,Q96PC5,Q92542,Q5JTV8,Q9NPA0,Q00765,P0CG08,P01889,O15260,P51571,Q8IYS2,Q9UNL2,Q96S66,Q8TBQ9,Q5J8M3,P55899,P15954,P12235,P04035,O75915,P05141,Q8NCG7,Q92544,Q9NZ43,P09493,A1L0T0,O14678,Q96AQ8,Q96I36,Q96NB2,Q9NWS8,Q86Y82,Q8NHH9,O14967,O15031,Q92581,Q8N5B7,Q4KMQ2,O94901,O75448,O75381,P11117,Q9UPR3,P51572,Q8TBP6,Q969X5,O14735,P41440,O14880,Q9NTJ5,P10586,Q9UKR5,P51790,P05067,O15269,Q03519,Q9Y3A6,Q9UBV2,Q9P0I2,Q9GZP9,P28288,O15126,Q12893,Q9NVH1,Q9H2J7,Q8TCT9,Q03518,P56589,Q8TEM1,Q8N766,Q96TC7,Q8WVX9,P49257,P04843,O95140 307 +Transporters 0.5554212719773324 6.1933480671043375 5.889946264314633e-10 1.236888710320865e-08 3.092221794015183e-09 412 Q9P0I2,Q9GZP9,Q14108,P53007,Q8N4V1,P28288,O15126,Q9H061,P45880,Q9H2J7,Q03518,Q15629,P56589,O75477,Q8WTV0,Q99720,Q8TEM1,Q8WY22,Q8N511,Q8N766,P24390,O60637,P49257,P04843,O95140,Q70HW3,P49755,P08183,Q7Z3B4,Q14849,P40855,Q9C0H2,Q5BJF2,Q5T9L3,O43772,Q5VW38,Q969V3,Q9BSK2,Q9BUN8,Q96QD8,Q9NR77,Q9BTX1,P07602,Q8TB61,Q9HC07,Q9H2D1,O75844,Q9UBX3,Q9Y6C9,Q9HD20,P27105,Q96N66,Q9NZJ7,Q16739,Q9HC21,Q86VD7,Q8TAA9,Q96A57,P35670,Q5SR56,O15118,P13073,Q8IUH4,O96005,Q8TCT8,Q6KCM7,Q8IXU6,Q6UW68,P21912,Q07065,Q96A33,Q99805,P35613,O75955,P16615,Q9H3N1,Q9NQZ5,O15127,P46934,Q9Y6M7,Q8TBA6,Q15070,Q15363,Q9UM00,P00403,P57088,P46977,O14681,Q6ZXV5,P12236,Q8NE00,Q5W0Z9,Q9Y287,Q16891,P13473,Q93050,O76024,Q9BUB7,Q12846,Q6P4A7,Q96RL7,P11279,Q12959,O96008,Q08722,O95202,Q6P4Q7,P30825,Q6NTF9,Q9BRK5,O95563,Q9UH99,Q9UBU6,P05023,O43808,Q8NHS3,Q9Y320,O15258,O60313,O95067,Q96PC5,Q9NPA0,O15260,Q9Y512,Q96S66,Q6NUK1,Q5J8M3,P15954,P12235,P04035,O75915,P05141,Q92544,O14678,O43681,Q96NB2,Q8NHH9,Q92581,Q4KMQ2,O94901,O75381,P51572,Q8TBP6,O15504,Q9UJS0,P61916,P41440,O60826,P05067,Q03519,Q9UBV2 151 +Metabolic proteins 0.3300653050107183 2.157754670023679 0.0309469109365969 0.4832279978860382 0.1083141882780893 977 O43924,P09960,Q9NRA0,P30519,P49589,Q16850,O75964,Q06136,P37268,P49354,Q8WTV0,P67812,O14949,O43676,Q9H773,Q8NCC3,Q9UDW1,Q70HW3,P07099,Q15165,P50897,Q15392,O76062,P08183,Q9UHG3,Q14849,Q8N4Q0,Q8NF37,P09601,Q9BRR6,O43772,P04062,Q86Y39,P03886,P51648,Q13510,Q86YN1,O60725,Q96QD8,Q8N2A8,Q9BTX1,P07602,Q8TB61,P51812,Q9H2D1,O75844,Q9NPH0,Q15800,Q9UBX3,Q14739,O14773,Q96N66,P40939,O95470,Q8IXJ6,P36896,Q16739,Q9HC21,Q86VD7,O15118,Q96G23,P13073,Q8IUH4,P22830,Q9UKU0,Q5H8A4,P48449,Q8NCH0,Q9UMR5,Q9UG56,Q9NWM8,Q9Y6M9,Q53GQ0,Q9HC38,P55786,Q10472,P21912,O00116,P00374,O95864,Q9P035,P16615,Q9NQZ5,Q9H7Z7,O14874,P46934,Q92604,Q9Y6M7,P43490,Q6Y1H2,O43292,Q9BT22,P54802,P16435,P00403,Q13423,Q8N4A0,Q9UIJ7,P46977,Q13126,Q9P0J0,Q14534,P12236,P27544,Q13011,P17900,Q5W0Z9,Q8N6G5,Q92643,P00813,Q8IV08,Q13232,P10619,Q10713,Q15005,Q9UKK9,Q9Y680,Q93050,P16278,Q9H490,Q9UBM7,P23786,P21964,Q6UX53,P08574,Q16134,Q9NZ01,O15121,O95168,P30825,P51970,Q9BTU6,Q9HCL2,Q9NUQ2,Q2TAA5,P0DMN0,O96000,O95563,O00767,Q9BWD1,P83881,P24539,P05023,P49748,O43808,O43505,Q7LGA3,Q8TED1,Q99735,P53701,Q86Y07,Q969T7 152 +Predicted secreted proteins 0.4813271020752024 2.0622387015913217 0.0391850157664883 0.5680483714308673 0.117555047299465 55 P61916,P22466,Q92520,Q9UM22,P80303,Q9Y4P3,P43490,Q15165,P14735,Q02818,P05067,O94919,Q8WUJ1,Q9HB40,Q9Y287 15 +CD markers 0.5402041728487281 1.6531131237397874 0.0983078428890691 0.8861785440869225 0.2293849667411613 19 P35613,P13473,P11279,P08183 4 +Potential drug targets 0.330916231542726 1.529974535670808 0.1260230321235711 0.9409119385310404 0.2355626612728472 527 Q14108,P53007,P28288,Q9NRA0,Q9H061,Q96GD4,P49589,Q53H12,Q03518,P56589,Q06136,P37268,O75477,Q8N766,Q8N511,Q8WVX9,P49257,P12694,O95140,Q70HW3,P07099,P50897,Q15392,P40855,P08236,P07237,P09601,O43772,P04062,P51648,Q16740,Q13510,P07602,P51812,Q9HC07,Q9H2D1,O75844,Q15800,Q14739,O14773,Q96N66,P40939,O95470,P36896,Q9HC21,Q86VD7,Q8TAA9,P35670,O15118,P13073,P22830,Q9UKU0,P48449,Q8NCH0,Q9NWM8,P21912,O00116,Q96A33,O14874,Q8TBA6,Q9BT22,Q9UM00,P54802,P16435,P00403,P46977,P42892,Q13126,O14681,Q6ZXV5,Q92643,Q8IV08,Q9Y287,P10619,Q10713,P13473,O76024,Q9BUB7,P16278,Q9UBM7,Q6P4A7,Q96RL7,P08574,Q9NZ01,Q6P4Q7,O15121,Q2TAA5,Q5VV42,P49748,Q8NHS3,Q9Y320,P53701,O60313,Q96PC5,Q8NI60,Q96S66,Q6NUK1,O14678,Q92581,Q4KMQ2,O75381,P11117,P51572,Q9UJS0,P61916,Q96T60,P22695,P10586,O60826,P04179,O15269,Q03519 112 +FDA approved drug targets 0.3531695322724171 1.4166411050583023 0.1565878841976167 0.9720207193422016 0.2355626612728472 136 Q16739,Q8N0U8,Q16850,P49721,P49354,P23786,Q99720,P12235,P04035,P05141,P21964,Q16134,Q96ER9,P00374,O95864,P16615,P03886,P10253,Q96QD8,P05023,Q13423,Q14534,Q7L0J3,P12236,P14735,P05067,P12814,P00813,P38435 29 +Ribosomal proteins 0.3232448419612651 0.9587406682038836 0.3376894054840051 0.9998252988570386 0.417145736186124 131 Q96GC5,Q02878,P39023,P27635,P61927,Q96A35,Q9NWU5,P84098,P18124,Q9BYD1,P62266,P62910,P46779,P50914,P62424,P82933,Q9BYD2,P82663,P46776,P49406,P47914,P40429,P61513,Q13084,P46778,O76021,P62917,Q9Y3B7,Q5T653,P82650,P82930,Q07020,P61313,P83881,Q9Y2R9,P36578,Q9HD33,Q7Z7H8,Q9BYN8,O95478,Q9Y3U8,P82912,P62241,P18077,Q92665,Q02543,Q9Y3D9,P62847,P62854 49 +Human disease related genes 0.2782270999782346 0.7671600541655246 0.4429863597734078 0.9999953955004198 0.5168174197356425 1021 Q9BQE5,O43924,Q14108,Q03252,P53007,P30533,P28288,Q9H061,P49589,Q53H12,Q03518,P56589,Q06136,O75477,Q99720,O14949,Q86YV9,Q8N511,Q8N766,Q969G3,P22466,Q96CU9,Q15427,O43676,Q8WVX9,P49257,P82663,P12694,O95140,P49711,Q70HW3,P07099,Q9Y6B6,P50897,Q15392,P08183,P40855,P08236,P07237,P09601,O75880,Q8N2K0,P22626,O43772,O00255,P04062,Q9UPT5,Q86Y39,Q9H488,Q92796,P03886,P51648,Q16740,Q13510,Q14574,O75352,O43819,Q96TA2,Q6UX04,Q2M389,Q9NR77,Q9Y619,P07602,P51812,P18077,Q9HC07,O14979,O75844,P35241,P50454,Q8TCJ2,Q15800,Q9UBX3,Q14739,Q9NX14,O14773,Q9BY67,Q13724,P98175,Q96N66,P40939,O95470,P38435,P14314,Q86XL3,Q15041,Q9HC21,Q9UHX1,Q8TAA9,P35670,O15118,Q01105,P22830,Q5H8A4,P48449,Q8NCH0,Q9NWM8,Q9Y6M9,O75503,P21912,O00116,P00374,Q5XKP0,P16615,Q9NQZ5,Q9H7Z7,O14874,O43292,P61313,Q9BT22,Q9UM00,P54802,P16435,P00403,Q13423,P46977,P42892,Q9P0J0,Q6ZXV5,P27544,P17900,P02545,Q92643,P00813,Q8IV08,Q9Y287,P10619,Q10713,P13473,Q9NVI7,O76024,Q9BUB7,P10321,P16278,Q9H490,Q9UBM7,P23786,Q6P4A7,Q96RL7,P50402,P08670,P21964,P08574,Q16134,Q8TB36,Q9NZ01,O95202,Q6P4Q7,O15121,Q9BTV4,Q2TAA5,O96000,Q6PGP7,Q7RTS9,P05023,Q5VV42,P49748,O43505,Q8NHS3,Q9H078,Q9Y320,Q9Y4P3,P53701,O60313,Q96IX5,Q9Y375,Q9NPL8,Q92542,Q5JTV8,Q8NI60,P55795,P01889,P51571,Q6NUK1,P12235,P09493,O14678,Q8N183,Q96HY6,Q96I36,Q9NWS8,Q92581,Q4KMQ2,P20700,O75381,P11117,Q6DKK2,P82930,P51572,Q969X5,P10253,O75380,Q9UJS0,P61916,Q96T60,P22695,Q8TB37,O14656,P35637,Q8WWV3,O60826,P05067,P04179,O15269,P12814,Q03519 206 +Candidate cardiovascular disease genes 0.4156008601914357 0.5004493726522836 0.6167586959479221 0.9999999982097302 0.6816806639424402 10 Q15165 1 +Disease related genes 0.260483228881385 0.3515256333027167 0.7251940453864323 0.999999999998342 0.7614537476557539 1140 O43924,Q14108,Q03252,P53007,Q13432,P30533,P28288,O95684,Q9NRA0,Q9H061,Q96GD4,Q8TAD8,P49589,Q53H12,P23246,Q03518,P56589,Q06136,P37268,O75477,Q01844,Q99720,O14949,Q86YV9,Q8N511,Q8N766,Q969G3,P22466,Q96CU9,Q15427,O43676,Q8WVX9,P49257,P12694,O95140,P49711,Q70HW3,P07099,Q9Y6B6,P50897,Q15392,P08183,P40855,P08236,P07237,P09601,O75880,Q8N2K0,Q9Y2R0,P22626,O43772,O00255,P04062,Q86Y39,Q9H488,Q92796,P03886,P51648,Q16740,Q13510,Q14574,Q02978,O75352,O43819,Q96TA2,Q6UX04,Q2M389,Q9Y619,P07602,P51812,P18077,Q9HC07,Q9H2D1,O75844,O14979,Q8N5M9,P35241,P50454,Q8TCJ2,Q15800,Q14739,Q9NX14,O14773,Q13724,P98175,Q96N66,P40939,O95470,P38435,P14314,P07196,Q86XL3,Q8WWI5,Q9UGP8,P36896,Q15041,Q9HC21,Q86VD7,Q9UHX1,Q8TAA9,P35670,O15118,Q01105,P13073,P22830,Q9UKU0,Q5H8A4,P48449,Q8NCH0,Q9NWM8,Q9Y6M9,O75503,P21912,O00116,P00374,Q5XKP0,Q96A33,P16615,O14874,Q8TBA6,O43292,P61313,Q9BT22,Q9UM00,P54802,P16435,P00403,Q13423,P46977,P42892,Q13126,Q9P0J0,O14681,Q6ZXV5,P27544,P17900,P02545,Q92643,P00813,Q8IV08,Q9Y287,P10619,Q10713,P13473,Q9NVI7,O76024,Q9BUB7,P10321,P16278,Q9H490,Q9UBM7,P23786,Q6P4A7,Q96RL7,P50402,P08670,P21964,Q9BS16,P08574,Q16134,Q8TB36,Q9NZ01,Q6P4Q7,O15121,Q9BTV4,Q2TAA5,Q6PGP7,Q7RTS9,P05023,Q5VV42,P49748,O43505,Q8NHS3,Q9H078,Q9Y320,Q9Y4P3,P53701,O60313,Q96IX5,Q9Y375,Q9NPL8,Q96PC5,Q92542,Q5JTV8,Q8NI60,P55795,P01889,P51571,Q96S66,Q6NUK1,P12235,P09493,O14678,Q8N183,Q96HY6,Q96I36,Q9NWS8,Q92581,Q4KMQ2,P20700,O75381,P11117,Q6DKK2,P82930,P51572,Q969X5,P10253,O75380,Q9UJS0,P61916,Q96T60,P22695,Q8TB37,P10586,O14656,P35637,Q8WWV3,O60826,P05067,P04179,O15269,P12814,Q03519 223 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4ae88492134ea84412c6037662b2957787e10117 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Nuclear receptors", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACVR1B", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP5M1", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARID4A", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHA", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BCS1L", "BDH2", "BET1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRI3BP", "BRIP1", "BRIX1", "BRMS1L", "BROX", "BRPF3", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C16orf58", "C16orf62", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C21orf59", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "C7orf26", "C8orf33", "C8orf59", "CAB39", "CACTIN", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC59", "CCDC6", "CCDC8", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC123", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDKAL1", "CDKN2AIP", "CDR2L", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPI", "CENPK", "CENPQ", "CENPV", "CEP170", "CEP250", "CEP290", "CEP350", "CEP44", "CEP55", "CEP97", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHML", "CHMP1A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLN5", "CLNS1A", "CLP1", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG5", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD2", "COMMD4", "COMMD7", "COMMD8", "COMMD9", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "CORO1C", "CORO7", "COTL1", "COX11", "COX14", "COX2", "COX4I1", "COX5A", "COX5B", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf38", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND4C", "DENR", "DEPDC1B", "DERL1", "DERL2", "DFFA", "DFFB", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DIS3L2", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPDR1", "EPHA2", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC1", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAHD2A", "FAIM", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM208A", "FAM213A", "FAM234B", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXL18", "FBXO21", "FBXO22", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1B", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTA", "FOCAD", "FOXK1", "FOXRED1", "FPGS", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAN", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GATC", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPPB", "GMPR2", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH11", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "GXYLT1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HAUS4", "HAUS5", "HAUS8", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA6", "ITGB1", "ITM2B", "ITPA", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KANSL3", "KARS", "KAT7", "KCMF1", "KCTD10", "KCTD12", "KCTD15", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIF11", "KIF14", "KIF15", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIFBP", "KIN", "KLC1", "KLC2", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LEO1", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIG4", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRR1", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYPLA1", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MALT1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP7D3", "MAP9", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUR1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED23", "MED24", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL3", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIOS", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLEC", "MLLT1", "MMAB", "MMGT1", "MMS19", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL24", "MRPL27", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR14", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVB12A", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NEO1", "NES", "NF1", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA1", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2C2AP", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN3", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGFOD1", "OGT", "OIP5", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHPT1", "PHRF1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCD3", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNA1", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNMA2", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POM121C", "PON2", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R9B", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG2", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RMND1", "RMND5A", "RNASEH2A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SASS6", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCFD2", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL2", "SDAD1", "SDCBP", "SDCCAG3", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC14L2", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEH1L", "SEL1L", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SEZ6L2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGSH", "SGTA", "SH3BGRL3", "SH3BP4", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPRH", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC12A9", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC44A1", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG5", "SMG8", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN3", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT1A4", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF10", "TAF2", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D24", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TCP11L1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX2", "TFAM", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "TGS1", "THADA", "THAP11", "THEM6", "THG1L", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THTPA", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLK2", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMCO6", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM104", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM160", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM30A", "TMEM33", "TMEM41A", "TMEM43", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD1", "TMOD3", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM56", "TRIO", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TRUB2", "TSC2", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TSR3", "TSTA3", "TTC1", "TTC19", "TTC27", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTI2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", 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"VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS11", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS52", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR41", "WDR43", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WDR91", "WDR92", "WFS1", "WIPI2", "WIZ", "WLS", "WNK1", "WRAP53", "WRAP73", "WRN", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YES1", "YIF1A", "YIF1B", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZDHHC20", "ZFAND1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYM4", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCD3", "ABCD4", "ABHD12", "ACADVL", "ACAT2", "ACP2", "ACP6", "ACSL6", "ACTN1", "ACVR1B", "ADA", "ADPGK", "AGK", "AGPAT5", "AGPS", "AK3", "ALDH3A2", "ALG1", "ALG11", "ANKLE2", "ANO6", "APOL2", "APP", "ARL10", "ARL6IP1", "ARL6IP5", "ASAH1", "ASNA1", "ATAD3A", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP5F1", "ATP5L", "ATP6V0A1", "ATP7B", "AURKB", "B4GAT1", "BCAP31", "BCKDHA", "BCKDK", "BCL2L13", "BNIP1", "BRI3BP", "BSG", "C19orf70", "C5orf15", "CADM1", "CANX", "CARS", "CCDC22", "CCDC47", "CCDC51", "CCNB2", "CD47", "CDIPT", "CDKAL1", "CENPK", "CERS1", "CERS2", "CERS5", "CHST14", "CKAP4", "CLCC1", "CLCN3", "CLGN", "CLN5", "CLPB", "CLPP", 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0000000000000000000000000000000000000000..47fae198f187be38b2a5877fab4cf49c8490405b --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4e77f9890c775182c66b9fc5fb6d84e857e0cfa12a8508191e48fa6bdbd9c24d +size 98854 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3c42b784821d9c65736f4ae86c658f9a5634f786 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Endoplasmic reticulum 108 207 5.356819742375102 8.469954564611034e-08 55.37621359223301 196.57766990291265 1.2201083743235763 0.4903523338807414 18.868778270733547 13.264167600850914 1.8573715045605257 0.4308007257692164 6.451106577357621e-09 0.0050586270687672 4.384404596205032e-06 1.6338486685184645e-12 1.4002503798927644e-25 +Mitochondria 126 420 4.503713894391707 6.677609249994276e-06 110.1747572815534 400.5485436893204 0.4320244196044261 0.5794127039570083 42.49664228528663 36.15232166758906 2.0400795827803786 0.4211568684384254 7.17736445645213e-05 0.016041050250863 0.000392483331069 1.424682880488341e-07 8.987054313062944e-18 +Golgi apparatus 57 222 3.1395683553372846 0.0016919693589947 46.45873786407767 176.03155339805826 1.3643789213018729 0.3972771337532677 14.511319530749702 26.453870355965975 1.6568954592349954 0.4161874156663988 5.902202551676372e-05 0.3603472431938982 0.00848104396027 5.271569165129996e-06 3.490920804807592e-05 +Nuclear membrane 21 70 3.12611283770278 0.0017713357168887 16.817961165048544 62.713592233009706 0.5402747034161678 0.5293388535672136 7.339768502370818 5.865441797870943 1.2287110387783358 0.3803813474041967 0.013551735476916 0.5719294869760876 0.0925475883056227 0.0040635656328399 0.0001699114435414 +Vesicles 79 343 2.23610819583392 0.0253446847221321 63.69174757281554 303.19174757281553 0.3021616120018026 0.6308308858815788 16.21576692438533 35.60761931464484 1.2670437076534344 0.3993041904676221 0.0038975226104918 0.4755611074655173 0.2278714868655304 0.0228242750994531 0.0226895731940058 +Lipid droplets 2 10 2.0481424727704667 0.0405460412738469 3.0072815533980584 9.62621359223301 0.341030817631545 0.5500740955075814 1.9327141206562328 1.0125869172856077 0.8582489651663355 0.3093604356540435 0.0078387944068705 1.0 0.0211645746663273 0.0184993148019339 0.1058637057364033 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2799193d46ab8083ee79477fdd82df69fac246ba --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3561, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 166.84848484848484 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ed236b734e4277d1270ed0334c6bc6289d93bb00 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C072/C072_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e36ef32dd6d32fa48602890171870ba7be638f95 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,12 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endoplasmic reticulum 0.618070642282822 5.356819742375102 8.469954564611034e-08 2.7950812184790755e-06 9.316950021182136e-07 207 Q9GZP9,O43169,P30533,Q8TCT9,Q8N0U8,Q16850,Q03518,P37268,O75477,O95197,P43307,P49257,P46776,P04843,Q9Y6B6,O76062,Q14849,P61513,P07237,Q8NF37,Q5BJF2,Q5T9L3,P62917,Q9P2W9,P51648,O75352,Q9BUN8,Q9NQC3,P50454,Q8TCJ2,Q15800,Q9NXW2,Q13724,P14314,O95470,Q86XL3,Q9UGP8,Q15041,P27635,Q96A57,Q96KA5,Q13162,Q96G23,P18124,Q96KC8,Q969M3,P62266,O96005,Q8IY17,Q6UW68,Q9H3G5,Q9H6H4,Q96A33,Q14696,P46778,Q9P035,Q9H3N1,Q96CS3,O00264,O43292,Q9BT22,Q9UM00,P13674,P61803,O14681,Q6NUQ4,P27544,P04844,P62847,Q86UE4,Q8N6G5,Q8WUJ1,Q8IV08,Q9Y680,Q9UBM7,P50402,P21964,P27824,Q92791,Q70UQ0,Q9NZ01,Q14257,O00767,P83881,P36578,Q12981,Q99735,O43852,Q86Y07,Q96PC5,Q00765,Q9NR31,P0CG08,O15260,P51571,Q96S66,O75915,P47914,Q96HY6,Q8NHH9,O14967,Q8N5B7,Q96CN7,P51572,Q9Y3U8,O60826,O15269,Q03519 108 +Mitochondria 0.4511581320255647 4.503713894391707 6.677609249994276e-06 0.0002203375631086 5.509027631246103e-05 420 Q96GC5,Q8WWC4,O60830,Q9NS69,Q99595,Q69YU5,Q9NVH1,P45880,Q53H12,O75964,O14949,Q8WY22,Q96CU9,Q96TC7,P82933,Q8N4H5,P82663,O95140,Q70HW3,Q8WVI0,Q9UDX5,Q5TC12,Q13505,Q9Y2R0,Q96A26,O43772,Q5T653,Q8NBN7,Q86Y39,Q9UBI6,Q16740,O75352,O43819,Q96TA2,Q7Z7H8,Q9BXW7,Q9BYN8,Q3SXM5,Q9H2D1,Q9UBX3,Q9NX14,Q9Y6C9,P40939,Q8WWI5,Q9Y3D6,Q9GZT3,Q99797,Q9HC21,Q86VD7,Q9H4I3,P13073,O14925,Q9Y6M9,Q6KCM7,P21912,P00374,Q5XKP0,Q9NX40,Q13084,Q9NQZ5,Q9H7Z7,Q9Y277,O14874,O43292,Q15070,Q13423,Q9UIJ7,Q9P0J0,P12236,Q13011,Q6UXV4,Q9BXK5,Q16891,Q10713,Q9NVI7,Q07820,Q9BUB7,P23786,Q6P4A7,P08574,O96008,Q8TB36,Q96ER9,O95202,O15121,O95168,P51970,Q9HCL2,Q9NUQ2,Q9H3K2,Q9NUJ1,P24539,P49748,Q7LGA3,Q99623,P53701,O60313,Q96IX5,Q9Y375,Q9NPL8,Q8NI60,O43615,Q9NWU5,Q9Y512,Q9NX63,Q6NUK1,P12235,P05141,Q5T9A4,O75431,Q8N183,Q96I36,Q96NB2,Q9NWS8,P56385,Q9Y394,Q6DKK2,P82930,O75947,Q9UJS0,Q9HD33,P22695,Q8TB37,P52789,P06576,P04179 126 +Golgi apparatus 0.4509079796521323 3.1395683553372846 0.0016919693589947 0.0543495465538421 0.0097423464428878 222 Q8NBN3,O60499,Q93050,O15260,P35670,Q8IYS2,Q9H8H2,P16278,Q8IUH4,Q9H4A6,P67812,Q5BJH7,Q8NCH0,P55327,P24390,P22466,O60637,Q9UG56,Q9NWM8,A1L0T0,Q8IXU6,P53367,P50897,O43760,Q02818,Q86Y82,Q8N4Q0,P09601,Q6NTF9,O75955,Q9BRK5,O00461,O15127,P80303,Q5VW38,Q7RTS9,Q9HD45,Q9BV57,Q8TBA6,Q9UBU6,Q8IZA0,Q9HB40,O75071,Q8N4A0,Q8NC54,Q9NPR9,Q92520,Q9NTJ5,Q9HC07,Q96SU4,O14681,P10586,O95070,Q8NE00,O15258,O95067,Q9Y287 57 +Nuclear membrane 0.5703963343066228 3.12611283770278 0.0017713357168887 0.0568273344964145 0.0097423464428878 70 Q5JTV8,O15260,Q96G23,P67812,Q96SK2,P50402,Q6UW68,O95168,Q14728,Q8N5B7,P20700,O94901,Q5SNT2,Q9H1E5,Q8IXM6,Q9UH99,O14735,O94919,Q9BTX1,O14656,Q14739 21 +Vesicles 0.3747722331903908 2.23610819583392 0.0253446847221321 0.5713677604820584 0.104546824478795 343 Q8N128,O15126,Q8IXH7,Q9H2J7,P30519,Q8WTV0,P24390,P22466,Q8NCC3,O95772,P50897,O76062,P42785,Q14849,Q8N4Q0,Q9HD45,Q86YN1,Q9NPR9,P07602,Q8TB61,Q3SXM5,Q8N5M9,O95070,Q9HD20,P27105,O60499,Q9NRY5,O15118,O75153,Q8IUH4,Q8IWB1,Q96SK2,Q5BJH7,Q9UMR5,Q8TCT8,Q6KCM7,P35613,O75955,O15127,Q15363,P16435,Q14534,P17900,Q5W0Z9,Q9Y287,P10619,Q9UKK9,P13473,Q93050,Q9H8H2,P16278,Q9H4A6,Q6P4A7,P21964,Q12959,Q6UX53,Q92791,O43482,Q08722,Q9NRV9,Q96M27,Q8NHS3,Q9Y3E0,Q8TBQ9,A1L0T0,P53367,Q9UBC2,Q86Y82,Q92581,Q96CN7,Q13595,Q969X5,P10253,Q96SU4,P52789,O14656,P51790,O60826,P05067 79 +Lipid droplets 0.7197673097813644 2.0481424727704667 0.0405460412738469 0.7448494021012202 0.1486688180041055 10 Q8NF37,Q969V3 2 +Peroxisomes 0.5904409385740772 1.7729806487011877 0.0762319135020535 0.9269571852916076 0.2286957405061604 16 O43808,Q8WVX9,O75381,P51659,P28288,P40855,Q5T8D3,Q9BY49,O00116,P56589,O15254 11 +Lysosomes 0.5239942842077155 1.2823098025749489 0.1997339906216526 0.9993591826777912 0.4119513556571585 14 Q8WTV0 1 +Centriolar satellite 0.3656001159422023 0.7306209544223929 0.4650107092564228 0.9999999989151044 0.6393897252275814 30 O43169 1 +Focal adhesion sites 0.2905201727423322 0.141444808748998 0.8875185578069122 1.0 1.0 30 Q9Y6M7,P08183 2 +Kinetochore 0.3214386063501028 0.1033933538845313 0.9176507867101058 1.0 1.0 2 Q9BZD4 1 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..320b8d1dfe0d0afe4eb2b2a682b893dbc20bd49a --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AACS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACVR1B", "ADA", "ADAR", "ADD1", "ADD2", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG2", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APEH", "APEX1", "API5", "APIP", "APLP2", "APMAP", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID3B", "ARID4A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC5", "ARSA", "ARVCF", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG13", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATP7B", "ATPAF1", "ATPIF1", "ATRIP", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCOR", "BCR", "BDH2", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOD1L1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAP", "BRAT1", "BRCA1", "BRD1", "BRD2", "BRD3", "BRI3BP", "BRIP1", "BRIX1", "BRMS1L", "BROX", "BRPF3", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C12orf57", "C12orf73", "C16orf58", "C16orf62", "C17orf75", "C19orf25", "C19orf53", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD5", "C2orf49", "C5orf15", "C5orf51", "C7orf26", "C8orf33", "C8orf59", "CAB39", "CACTIN", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CASP8", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC138", "CCDC22", "CCDC47", "CCDC51", "CCDC59", "CCDC6", "CCDC8", "CCDC86", "CCDC97", "CCNA2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC123", "CDC25C", "CDC27", "CDC34", "CDC37", "CDC40", "CDC42", "CDC45", "CDC5L", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDKN2AIP", "CDR2L", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPI", "CENPQ", "CENPV", "CEP170", "CEP250", "CEP290", "CEP350", "CEP55", "CERS1", "CERS2", "CERS5", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CGN", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD3", "CHD4", "CHD8", "CHEK2", "CHID1", "CHKA", "CHML", "CHMP1A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLNS1A", "CLP1", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSPN", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT2", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG5", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD4", "COMMD7", "COMMD8", "COMMD9", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "COTL1", "COX14", "COX4I1", "COX5B", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSGALNACT2", "CSK", "CSNK1A1", "CSNK2A1", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTTNBP2", "CTU2", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf38", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D5", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENND4C", "DENR", "DEPDC1B", "DERL1", "DERL2", "DFFA", "DFFB", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX34", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG1", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DRAP1", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DTX3L", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNC2LI1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA2", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6B", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAIM", "FAM114A2", "FAM120A", "FAM120B", "FAM129B", "FAM162A", "FAM177A1", "FAM208A", "FAM234B", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXL18", "FBXO21", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEM1B", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FN3KRP", "FNBP4", "FNDC3A", "FNTA", "FOCAD", "FOXK1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNT2", "GALNT4", "GALNT7", "GAN", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGPS1", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPR2", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOT1", "GPAA1", "GPAM", "GPATCH11", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS2", "HAUS3", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC3", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HEXIM1", "HGH1", "HGS", "HIBCH", "HIF1AN", "HINT2", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSF1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "ICE1", "IDH1", "IDH2", "IDH3A", "IDH3B", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKG", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IRF2BP1", "IRF2BPL", "IRGQ", "ISG20L2", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITPA", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KANSL3", "KARS", "KAT7", "KCMF1", "KCTD10", "KCTD12", "KCTD15", "KDELC1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA2013", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF5C", "KIN", "KLC1", "KLC2", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNB1", "KRI1", "KRR1", "KTI12", "KTN1", "KYAT3", "L2HGDH", "L3MBTL3", "LACTB", "LAMC1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LEO1", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIG4", "LIMA1", "LIN28B", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRR1", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM8", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LUZP1", "LYAR", "LYPLA1", "LZTFL1", "LZTS2", "MACF1", "MACO1", "MAD2L1", "MAEA", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP4", "MAP7D3", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAM", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED1", "MED12", "MED14", "MED16", "MED17", "MED23", "MED25", "MED27", "MEN1", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL16", "METTL7B", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD8", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIOS", "MIPEP", "MKI67", "MKLN1", "MKRN2", "MLLT1", "MMAB", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL21", "MRPL22", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFP1", "MTHFD1L", "MTHFD2", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVB12A", "MVD", "MVK", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "MYO6", "MYO9B", "NAA10", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCAPH2", "NCBP1", "NCBP2", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEFL", "NEFM", "NELFA", "NELFCD", "NELFE", "NEMF", "NEO1", "NES", "NF1", "NFATC2IP", "NFRKB", "NFS1", "NFU1", "NHLRC2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME3", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA1", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NR2C2AP", "NR2F1", "NR3C1", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "ODR4", "OGDH", "OGFOD1", "OGT", "OIP5", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PAAF1", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PAPSS2", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PATL1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDSS2", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN1", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PHKB", "PHPT1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCD3", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PLXNA1", "PM20D2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGLUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POM121C", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAT", "PPCDC", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL1", "PPIL2", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4C", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKCZ", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN13", "PTPN9", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT2", "RAB12", "RAB13", "RAB14", "RAB1A", "RAB23", "RAB24", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAD51AP1", "RAE1", "RAI14", "RALA", "RALGAPB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP5", "RBBP6", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP4", "REEP5", "RELA", "REPS1", "RER1", "RETREG2", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RMND1", "RMND5A", "RNASEH2A", "RNF123", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPTOR", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAMP1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD2", "SCLY", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC14L2", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT8", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SHPRH", "SIN3A", "SIRT1", "SIRT2", "SKA1", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC3A2", "SLC44A1", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC6A15", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLK", "SMAD4", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMG5", "SMG8", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAP47", "SNAPIN", "SND1", "SNIP1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNTB2", "SNW1", "SNX1", "SNX17", "SNX2", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK26", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STRN3", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE1", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF10", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10A", "TBC1D13", "TBC1D15", "TBC1D24", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL1XR1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP11L1", "TDP2", "TDRD7", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2", "TERF2IP", "TES", "TEX10", "TEX2", "TFAM", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "TGS1", "THADA", "THAP11", "THEM6", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THTPA", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TJP1", "TJP2", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TMA16", "TMA7", "TMCO1", "TMCO6", "TMED10", "TMED2", "TMEM104", "TMEM109", "TMEM115", "TMEM126A", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM41A", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMLHE", "TMOD3", "TMPPE", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIM56", "TRIO", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSC2", "TSC22D3", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSR2", "TSR3", "TSTA3", "TTC1", "TTC19", "TTC27", "TTC37", "TTC38", "TTC4", "TTF2", "TTI1", "TTI2", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP4", "TUFM", "TWF1", "TWF2", "TWISTNB", "TXLNA", "TXLNG", "TXNDC16", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAC1", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE3D", "UBE4A", "UBFD1", "UBLCP1", "UBP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP22", "USP24", "USP32", "USP33", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VPS11", "VPS13C", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VTI1B", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WASL", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR26", "WDR3", "WDR36", "WDR41", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR70", "WDR77", "WDR82", "WDR92", "WIPI2", "WIZ", "WLS", "WNK1", "WRAP53", "WRN", "WTAP", "XAB2", "XIAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS4", "YES1", "YIF1A", "YIF1B", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZDHHC20", "ZFAND1", "ZFR", "ZFYVE16", "ZMYM2", "ZMYM4", "ZNF207", "ZNF277", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCD3", "ABHD10", "ACADVL", "ACBD5", "ACOX3", "ADI1", "AGK", "AGPAT5", "AGPS", "AK3", "ALDH3A2", "ALG1", "ANKLE2", "APOOL", "APP", "ARFIP1", "ARL6IP1", "ARL6IP5", "ATAD3A", "ATAD3B", "ATL2", "ATP13A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5L", "ATP6V0A1", "ATP7B", "ATPAF1", "BCAP31", "BCKDK", "BCL2L13", "BNIP1", "BRI3BP", "BSG", "C12orf73", "C19orf70", "C5orf15", "CALU", "CANX", "CCDC22", "CCDC47", "CCDC51", "CCNB2", "CD47", "CDIPT", "CERS1", "CERS2", "CERS5", "CHCHD3", "CHST14", "CLCC1", "CLCN3", "CLGN", "CLPP", "CLPTM1", "CLPTM1L", "CLUH", "COA3", "COMT", "COQ8A", "COX14", "COX4I1", "CPT2", "CPVL", "CSGALNACT2", "CTSA", "CYB5B", "CYB5D2", "CYC1", "CYP51A1", "DAD1", "DDRGK1", "DDX31", "DEGS1", "DERL1", "DERL2", "DHCR7", "DHFR", "DHRS7", "DLG1", "DNAJB12", "DNAJC1", "DNAJC11", "DOLPP1", "DYM", "ECH1", "EFCAB14", "EI24", "EMD", "ENDOD1", "EPS15L1", "ERGIC1", "ERLIN1", "FAF2", "FAM114A2", "FAM162A", "FAM177A1", "FAM3C", "FAM8A1", "FAR1", "FDFT1", "FIS1", "FKBP14", "FKBP7", "FLOT1", "FOXRED1", "GAA", "GAL", "GALNT4", "GDAP1", "GHITM", "GLB1", "GM2A", "GNG12", "GOLGA5", "GOLIM4", "GOLPH3", "GOLT1B", "GPAA1", "GPAM", "GPR107", "GPR108", "GPR89B", "HACD3", "HADHA", "HCCS", "HDHD5", "HEBP1", "HK2", "HM13", "HMOX1", "HMOX2", "HS2ST1", "HSD17B4", "HSDL1", "IKBIP", "ILVBL", "IMMT", "ISOC1", "ITM2B", "ITPRIP", "JAGN1", "KDELR1", "KIAA0319L", "KIAA2013", "LAMP2", "LBR", "LETM1", "LMAN1", "LMNB1", "LPCAT1", "LRPAP1", "MAIP1", "MCL1", "MESD", "METTL7B", "MFN2", "MFSD10", "MFSD8", "MGST2", "MIA2", "MIPEP", "MOGS", "MPDU1", "MRPL10", "MRPL2", "MRPL22", "MRPL28", "MRPL47", "MRPL48", "MRPS25", "MRPS26", "MRPS34", "MRPS9", "MSMO1", "MTCH2", "MTDH", "MTFP1", "MTX1", "MTX2", "NCLN", "NDC1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF1", "NDUFAF2", "NDUFB11", "NDUFB4", "NDUFB9", "NELFCD", "NNT", "NPC1", "NRM", "NUBPL", "NUCB1", "NUCB2", "NUDT5", "NUF2", "OCIAD1", "OIP5", "OPA1", "OSBPL9", "OXA1L", "P3H4", "P4HA1", "P4HB", "PECR", "PEX14", "PEX19", "PEX3", "PGRMC1", "PHB2", "PISD", "PLA2G15", "PLD3", "PMPCA", "PNPLA6", "POR", "PPT1", "PPT2", "PRCP", "PRDX4", "PRKCSH", "PRRC1", "PSAP", "PTGES2", "PTPRF", "RCN2", "RDH13", "REEP4", "REEP5", "RER1", "RHBDD2", "RMDN3", "RMND1", "RPL10", "RPL21", "RPL27A", "RPL29", "RPL36", "RPL36A", "RPL37A", "RPL4", "RPL7", "RPL8", "RPN1", "RPN2", "RPS23", "RPS24", "RTN3", "RTN4", "SACM1L", "SAMM50", "SAR1A", "SAR1B", "SCAMP1", "SCAMP2", "SCARB1", "SCD", "SCO2", "SCPEP1", "SDF4", "SDHB", "SEC11A", "SEC63", "SERPINH1", "SFXN2", "SFXN4", "SGPL1", "SLC25A10", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC35B2", "SLC35F2", "SLC44A1", "SLC4A7", "SLC6A15", "SLC9A6", "SLIRP", "SMIM4", "SOD2", "SPPL2A", "SPTLC1", "SQLE", "SSR1", "SSR4", "STARD3", "STARD3NL", "STARD7", "STOM", "STT3B", "STX10", "STX12", "STX18", "SUN1", "SUN2", "SURF4", "SYNGR2", "TAP1", "TAP2", "TECR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMMDC1", "TM7SF2", "TM9SF3", "TMCO1", "TMED2", "TMEM104", "TMEM165", "TMEM167A", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM70", "TMEM87A", "TMEM97", "TMX1", "TMX4", "TOMM22", "TOMM40", "TOMM5", "TOR1A", "TOR1AIP1", "TPD52", "TRA2A", "TRABD", "TSPAN3", "TTC19", "UQCRC2", "UQCRQ", "USMG5", "VDAC2", "VDAC3", "VKORC1L1", "VRK2", "WLS", "YIF1A", "YIF1B", "YIPF5", "YME1L1", "ZADH2", "ZDHHC13", "ZDHHC20"]} \ No newline at end of file