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010289f verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Regulation of expression of slits and robos 0.5522390761129214 6.727677044464578 1.7239301710839524e-11 2.447980954997259e-08 2.4479809849392123e-08 128 P62899,P18621,P35998,Q15008,P63220,P05387,P28066,O00233,P62266,P63173,P62263,P61513,P08708,P62081,P05388,O75832,A7E2V4,Q15369,P55036,P62857,Q99460,P35268,Q9UNM6,P61254,Q15370,P30050,Q02878,P25787,P61353,P25789,P25788,P46782,P62273,P62829,Q14118,P49720,P62854,P62753,Q9Y5S9,Q9Y3U8,P62280,P60866,P05386,O43242,O14818,O00487,P39019,P28072,P25398,P60900,P62249,P83731,P61927,P46777,P28074,P61289,P62847,P15880,P08865,P62888,P23396,P62750,P62244,P62241,P50914,P28070,P32969,P20618,P46776,P43686,P46781,Q13200,P62495,P62333,Q9UL46,P25786,Q9HAU5,P15170,P17980,P84098,P62195,P42766,O00231,O00232,Q99436,P62841,P62701,P62277,P62913,P61247,P62191 91
Signaling by robo receptors 0.5298277896919154 6.19908850857744 5.679109015701824e-10 8.064331567112576e-07 4.032167408248296e-07 147 P62899,P18621,P35998,Q15008,P63220,P05387,P28066,O00233,P62266,O43639,P63173,P62263,P61513,P08708,P62081,P05388,O75832,A7E2V4,P61586,Q15369,P55036,P62857,P17612,Q99460,P35268,Q9UNM6,P50552,P61254,Q15370,P30050,Q02878,P25787,P61353,P25789,P25788,P46782,P62273,Q01518,P62829,Q14118,P07737,P49720,P62854,P62753,Q9Y5S9,Q9Y3U8,P62280,P60866,P05386,O43242,O14818,O00487,P39019,P28072,P25398,P60900,P62249,P83731,P61927,P46777,P28074,P61289,P62847,P15880,P08865,P62888,P23396,P62750,P62244,P62241,P50914,P28070,P32969,P35080,P20618,P46776,P43686,P46781,Q13200,P62495,P62333,Q8N8S7,Q9UL46,P25786,Q9HAU5,P15170,P17980,P84098,P62195,P42766,O00231,O00232,Q99436,P62841,P62701,P62277,P62913,P61247,P62191 99
Class i mhc mediated antigen processing presentation 0.404553912961672 4.420409925606779 9.851384322079326e-06 0.0138916427663879 0.004662988579118 125 O95376,P09429,P28070,Q8TBC4,P20618,O43242,P43686,O14818,Q13200,O95352,Q9BSL1,O00487,Q92990,P62333,Q13404,Q9UNM6,P61086,Q63HN8,Q15436,P28072,P60900,P35998,O94822,Q15370,Q9UL46,Q5GLZ8,Q13309,P25787,Q8TDB6,P25788,P25789,P25786,Q9C0C9,P28066,O00233,Q9Y508,P68036,P17980,Q9Y6B6,P28074,P62195,P55735,P55786,P49720,P61289,P63208,O75832,O00231,Q99436,Q96PU5,Q9UNE7,P61081,Q15369,P55036,O15111,P62191,P49427 57
Metabolism of amino acids and derivatives 0.4334720099474199 4.124416925102365 3.716751095539372e-05 0.0514102266622729 0.0098252857419936 199 P62899,P08243,P00390,Q15046,P18621,O43708,Q9BV57,P17174,Q9UBQ7,P52788,Q15008,P19623,P35998,P63220,Q96I15,P05387,Q53H96,P28066,O00233,Q9Y617,P62266,P63173,Q9BV20,P62263,P61513,P08708,P62081,O75832,P05388,P55036,P62857,Q96GX9,Q99460,Q13155,P35268,Q9Y619,Q9UNM6,O43175,P61254,P30050,P23526,Q02878,P25787,P61353,P25789,P25788,P46782,P62273,P62829,Q13126,P25325,P49720,P62854,P62753,Q9Y3U8,O43324,P78330,P62280,P12277,P60866,P05386,O43242,O14818,O00487,O43252,P15104,P39019,P28072,P25398,P60900,P62249,P83731,P61927,P46777,P28074,P61289,P61457,P62847,P15880,P08865,P62888,P23396,P49591,P62750,P62244,P62241,P57772,P54136,P50914,P28070,P32969,P20618,P34896,P46776,P43686,P46781,Q13200,P62333,Q16881,Q9UL46,P25786,P21953,P17980,P84098,P14868,Q12904,P62195,P42766,O00231,O00232,Q99436,Q7L266,P62841,P62701,P62277,P62913,P61247,P62191 118
Nervous system development 0.4187815816209215 3.5839053902416644 0.0003384947375484 0.3816767478544465 0.0686660753312538 230 P62899,Q92796,Q16539,P18621,P60660,P23528,Q96P70,Q15008,P35998,P63220,P05387,Q00169,P28066,O00233,P62266,O43639,P67870,P63173,P62263,P61513,P08708,O75832,P05388,A7E2V4,Q9BUF5,Q00535,P61586,Q15369,P55036,P61160,P62857,O15145,P17612,Q9UNM6,P50552,P30050,Q15370,P26038,P25787,P25788,P25789,P62273,Q01518,P62829,Q14118,P59998,P07737,P49720,P62854,P62753,Q9Y5S9,Q9Y3U8,O00401,P62280,P09497,P60866,P05386,O43242,O14818,O00487,P39019,P28072,P25398,P60900,P62249,P19784,P83731,P61927,P46777,P04350,P28074,P61289,P62847,P68371,P62993,P15880,P08865,Q7Z406,P62888,P23396,P62750,P62244,P62241,P50914,P28070,P32969,P35080,P20618,P46776,Q06124,P43686,P46781,Q13200,P62495,P62333,Q15334,Q92747,Q8N8S7,Q9UL46,P25786,Q9HAU5,P15170,P27361,P17980,P84098,P15311,P62195,P42766,O00231,O00232,Q99436,O00560,Q96S59,P62841,P62701,P62277,P62913,P61247,P62191 119
Eukaryotic translation initiation 0.5687776480647734 3.4689551365920046 0.0005224866958739 0.5238988751963735 0.0927413885176277 104 P62899,P60842,P18621,P49770,P63220,P05387,P62266,Q9UBQ5,P63173,P62263,P61513,P08708,P62081,P05388,P05198,P62857,P35268,O15372,P61254,P30050,Q02878,P61353,O60841,Q7L2H7,P46782,P46778,P62273,P62829,P62854,Q14232,Q9NR50,P62753,Q9Y3U8,Q13347,P62280,P60866,P05386,O75821,P39019,P62851,P62424,P62269,P25398,P62249,P40429,Q15056,P83731,P61927,P46777,P62847,P15880,P08865,P06730,P26373,P18124,P62888,P23396,O15371,P62750,P62244,P62241,P50914,P60228,P32969,P46776,P62917,P62906,P62861,P46781,Q14240,O00303,P20042,P84098,P41091,Q13144,O75822,P55010,P42766,P62841,P62701,P62277,P62913,P61247 83
Deubiquitination 0.4119537004730359 2.729888442057063 0.0063355760869587 0.999879653810089 0.847638079324235 113 P28070,P20618,O43242,O14818,Q13200,Q9Y5T5,O00487,P62333,P54578,Q9UNM6,Q9Y4E8,P60900,P20248,Q13485,P35998,Q70CQ2,Q9NXR7,P25787,Q13309,P25788,P25789,P25786,P49407,P28066,O00233,O60493,Q96FW1,P51784,P28074,P06493,P62195,P54727,P49720,P61289,O75832,Q99436,O95630,Q9UPT9,P61586,Q9NZL9,P55036,Q9Y5K5,P62191 43
Signaling by interleukins 0.3387055414004754 2.609551212739982 0.0090661074585272 0.9999975820383904 0.847638079324235 119 P09429,P28070,P51617,P20618,Q06124,O43242,Q16658,O14818,O14733,Q13200,O00487,P62333,P46109,Q13404,Q9UNM6,P51452,P14174,P40763,P28072,P23528,P60900,P35998,P78417,P26038,P52564,P25787,P25788,P25789,Q00169,P25786,P28066,P40222,O00170,O00233,Q99439,P27361,Q13126,P28074,P62195,P49720,P61289,P63208,P05388,O75832,Q99436,P55036,P62191,P17612 48
Nucleotide salvage 0.7456035460996283 2.465097803625797 0.0136975857091525 0.999999996878692 0.847638079324235 8 P00491,P04183,P07741,P00492,Q01433,P55263 6
Purine salvage 0.739233276267196 2.4534615182083868 0.0141488677220917 0.9999999983703204 0.847638079324235 7 P00491,P07741,P00492,Q01433,P55263 5
Selenoamino acid metabolism 0.5744707199722074 2.4168685625382405 0.015654668812413 0.9999999998140356 0.847638079324235 92 P62244,P62241,P57772,P54136,P62899,P62280,P50914,P60866,P32969,P05386,P46776,P62917,P62906,P00390,Q15046,P18621,Q13155,P35268,P62750,P62861,P46781,P49207,O43252,P39019,Q16881,P62851,P62424,P62269,P25398,P62249,P30050,P61254,P23526,P40429,P63220,P41252,Q02878,Q96I15,P05387,P61353,P46782,P46778,P83731,P62273,P62266,P61927,P46777,P84098,P62829,P14868,P63173,Q12904,P62263,P61513,P08708,P62081,P05388,P62854,P62847,P42766,P15880,P08865,P62841,P62701,P62277,P26373,P61247,P18124,P62753,P62888,P62913,Q9Y3U8,P62857,P23396,P49591,O43324 76
Small interfering rna sirna biogenesis 0.8713743139369274 2.288323409804684 0.022118694214535 0.999999999999984 0.847638079324235 4 Q15631 1
Arachidonic acid metabolism 0.8315735488863841 2.2795116229795136 0.0226366698439126 0.9999999999999925 0.847638079324235 5 Q8N8N7,Q14914 2
Activation of ampk downstream of nmdars 0.6991016739866104 2.2280147799088357 0.0258795294273874 1.0 0.847638079324235 8 Q13131,Q9BUF5 2
Mrna decay by 5 to 3 exoribonuclease 0.7046397535993758 2.1973191435762067 0.0279976613850085 1.0 0.847638079324235 11 Q9Y333,Q86TB9,Q8IZH2 3
Bbsome mediated cargo targeting to cilium 0.6887826820354184 2.195971468691505 0.0280939855975328 1.0 0.847638079324235 7 P50991,Q9H0F7,P48643,P78371,P17987,P50990 6
Recycling of eif2 gdp 0.6921677223350574 2.192142236069392 0.0283692378459154 1.0 0.847638079324235 8 P49770,Q14232,P41091,Q9NR50,Q13144,P05198 6
Folding of actin by cct tric 0.6889763779527549 2.175587091261165 0.0295861494458149 1.0 0.847638079324235 8 P50991,P48643,P78371,P40227,P17987,P50990,Q99832 7
Methylation 0.6926652084180505 2.1740802849701684 0.0296991062933562 1.0 0.847638079324235 9 Q9UI30,Q9HBK9,P78417,P23526,Q9NZL9,P51580 6
E2f enabled inhibition of pre replication complex formation 0.6763708811619165 2.13152224528567 0.0330461417978664 1.0 0.847638079324235 7 O43929,Q9Y619,P06493 3
S phase 0.4398765851450781 2.0896600583612126 0.0366483473557863 1.0 0.847638079324235 105 P24941,P28070,Q9UBD5,P20618,P06400,O43242,P43686,Q15054,O14818,Q13200,O00487,Q9Y248,P62333,Q9Y619,Q9UNM6,P49643,Q9BRT9,P15927,Q99741,P28072,O43929,P20248,P60900,P35998,Q15008,P33991,Q9UL46,P25787,Q13309,P25789,P25788,Q5TKA1,P12004,P25786,P18858,P28066,O00233,P17980,Q9NR33,P51530,P28074,P62195,P49720,P61289,Q9BRX5,P63208,O75832,O00231,O00232,Q99436,P11802,P55036,P35250,P62191,P49642,P27694,P39748 57
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.6746672927587127 2.0800675944179936 0.0375193334001837 1.0 0.847638079324235 9 Q86X55,P06493,P30307,Q99873 4
Phenylalanine and tyrosine metabolism 0.8150693441268761 2.0504221392942448 0.040323254575286 1.0 0.847638079324235 4 P61457,Q7L266 2
Cellular response to starvation 0.5198021576557786 1.9624292383339756 0.0497125314870885 1.0 0.847638079324235 93 P62244,P62241,P62899,P21281,P62280,P50914,P60866,P32969,P05386,P08243,P46776,P62917,P62906,P62861,P46781,P18621,P35268,P21283,P39019,P62851,P62424,P62269,P25398,P62249,P61254,P30050,P40429,P63220,Q02878,P61353,P05387,Q92616,P46782,P46778,P83731,P62273,P62266,P61927,Q8NFG4,P46777,P20042,P84098,P62829,P41091,P63173,P62263,P55735,P61513,P08708,P62081,P05388,P05198,P62854,P62847,P42766,P15880,P08865,P62841,P62701,P62277,P26373,P62913,P18124,P62753,P62888,P61247,Q9Y3U8,P62857,P23396,P62750 70
Purine ribonucleoside monophosphate biosynthesis 0.65591219322325 1.960611378499805 0.0499243740248149 1.0 0.847638079324235 10 P22234,P22102,P30520,Q06203,P12268,P20839,P49915,P30566 8
Raf independent mapk1 3 activation 0.7220634959096531 1.945566034056624 0.0517068903820083 1.0 0.847638079324235 6 Q99956,P06493,Q06124 3
Adaptive immune system 0.3226548565201573 1.9415576127843344 0.0521906784675991 1.0 0.847638079324235 212 P35998,Q13309,Q8TDB6,P28066,O00233,Q9Y508,P47755,O95999,Q9Y6B6,Q07866,O75832,Q9BUF5,P61081,Q15369,P55036,P17612,P47756,P49427,Q8TBC4,O95352,Q9UNM6,Q13404,P50552,O94822,Q15370,P25787,P25788,P25789,P55735,P55786,P49720,Q96PU5,Q9UNE7,O43237,P63167,O43242,O14818,Q9BSL1,O00487,P61163,P61086,P28072,P60900,Q5GLZ8,Q13409,P68036,Q9UJW0,P04350,P28074,P61289,P63208,P68371,P62993,P05771,O15111,O95376,P09429,P28070,P31946,P20618,P41240,Q06124,P43686,Q13200,Q92990,P62333,Q99538,Q8N8S7,Q63HN8,Q15436,Q9UL46,P25786,Q9C0C9,P17980,P62195,O43865,O00231,Q99436,Q9BXS5,P62191,Q9NZ32 81
Carboxyterminal post translational modifications of tubulin 0.6388758885426574 1.934276968144231 0.0530790834566115 1.0 0.847638079324235 7 Q9BUF5,Q14166 2
Polb dependent long patch base excision repair 0.6380034068346612 1.929643057218372 0.0536510799321803 1.0 0.847638079324235 7 P27695,P39748,P18858 3
Glutathione synthesis and recycling 0.7174393206019798 1.9238345325485864 0.0543753274117424 1.0 0.847638079324235 6 O75223,Q8WUX2,P48507 3
Synthesis of prostaglandins pg and thromboxanes tx 0.9177140770138648 1.9015710220183488 0.057227259330584 1.0 0.847638079324235 3 Q8N8N7 1
Interconversion of nucleotide di and triphosphates 0.6674520984463649 1.8977398325980952 0.0577303626015457 1.0 0.847638079324235 17 P35754,P31350,P30085,Q16881,Q9H773,P33316,P00568,P00390,P32321,P15531,P22392,P17812,P23921,Q9NRF8 14
Activated tak1 mediates p38 mapk activation 0.7112828787799851 1.8948368712796313 0.0581140167306584 1.0 0.847638079324235 6 Q13404,P52564 2
Mapk3 erk1 activation 0.7730449267431583 1.8693108554861215 0.061579578713081 1.0 0.847638079324235 4 Q06124,P06493 2
Antigen processing ubiquitination proteasome degradation 0.4530587039747124 1.86819806834932 0.0617344679464006 1.0 0.847638079324235 101 O95376,P28070,Q8TBC4,P20618,O43242,P43686,O14818,Q13200,O95352,Q9BSL1,O00487,Q92990,P62333,Q13404,Q9UNM6,P61086,Q63HN8,P28072,P60900,P35998,O94822,Q15370,Q9UL46,Q5GLZ8,Q13309,P25787,Q8TDB6,P25788,P25789,P25786,Q9C0C9,P28066,O00233,Q9Y508,P68036,P17980,P28074,P62195,P55786,P49720,P61289,P63208,O75832,O00231,Q99436,Q96PU5,Q9UNE7,P61081,Q15369,P55036,P62191,P49427 52
Synthesis of dna 0.5293512712557765 1.8663153333629243 0.0619972607755325 1.0 0.847638079324235 90 P24941,P28070,Q9UBD5,P20618,O43242,P43686,Q15054,O14818,Q13200,O00487,Q9Y248,P62333,Q9Y619,Q9UNM6,P49643,Q9BRT9,P15927,Q99741,P28072,O43929,P20248,P60900,P35998,Q15008,P33991,Q9UL46,P25787,Q13309,P25789,P25788,P12004,P25786,P18858,P28066,O00233,P17980,Q9NR33,P51530,P28074,P62195,P49720,P61289,Q9BRX5,P63208,O75832,O00231,O00232,Q99436,P55036,P35250,P62191,P49642,P27694,P39748 54
Mitotic g2 g2 m phases 0.4674034193856485 1.8613796041118496 0.062690588765601 1.0 0.847638079324235 99 P63167,P24941,P28070,P07437,P20618,Q9Y570,O43242,P43686,O14818,Q13200,O00487,Q9BSJ2,P61163,Q9H6D7,P62333,Q9UNM6,P28072,Q99640,P60900,P20248,P35998,Q15008,Q9UL46,Q96CW5,P25787,P25788,P25789,O75665,Q13409,Q5TKA1,P25786,P28066,O00233,P17980,P04350,P28074,P06493,P62195,P49720,P61289,O43805,P63208,O75832,P30307,P68371,O00231,O00232,Q99436,Q15691,P62258,Q9BUF5,P63151,P55036,P62191,P17612 55
Dna replication 0.4881602946077417 1.853355488333024 0.0638314227935121 1.0 0.847638079324235 96 P24941,P28070,Q9UBD5,P20618,O43242,P43686,Q15054,O14818,Q13200,O00487,Q9Y248,P62333,Q9Y619,Q9UNM6,P49643,Q9BRT9,P15927,Q99741,P28072,O43929,P20248,P60900,P35998,Q15008,P33991,Q9UL46,P25787,Q13309,P25789,P25788,P12004,P25786,P18858,P28066,O00233,P17980,Q9NR33,P51530,P28074,P62195,P49720,P61289,Q9BRX5,P63208,O75832,O00231,O00232,Q99436,P55036,P35250,P62191,P49642,P27694,P39748 54
Metabolism of cofactors 0.7007012574603322 1.8448258279443837 0.0650628790245633 1.0 0.847638079324235 6 P00374 1
Mitotic g1 phase and g1 s transition 0.5568470262569474 1.8446937915508417 0.0650820945172516 1.0 0.847638079324235 85 P00374,P24941,P28070,P20618,P06400,O43242,P43686,O14818,Q13200,O00487,P62333,Q9Y619,Q9UNM6,P49643,P15927,Q99741,P28072,O43929,P20248,P42771,Q15008,P35998,P33991,P60900,P30153,Q9UL46,P25787,Q13309,P25788,P25789,Q5TKA1,P12004,P25786,P28066,O00233,P04183,P17980,Q9NR33,P28074,P06493,P62195,P49720,P61289,P63208,O75832,O00231,O00232,Q99436,P31350,Q00534,P11802,P63151,P55036,P62191,P49642,P27694,Q9UBD5 57
Separation of sister chromatids 0.2850029376007085 1.8252373060874032 0.0679652263850756 1.0 0.847638079324235 120 P63167,P28070,P20618,O43242,O14818,Q13200,O00487,P62333,Q9UNM6,Q96EA4,P60900,P35998,O43684,P25787,P25788,P25789,Q13409,P25786,Q8N0S6,P28066,O00233,Q9P258,P04350,P28074,P62195,P55735,P49720,P61289,O75832,Q99436,Q9H900,Q15691,Q9HBM1,Q9BUF5,P55036,P62191,Q9Y266,O43237 38
Hiv infection 0.2781918820032122 1.8198881469552777 0.0687760403396564 1.0 0.847638079324235 143 P28070,P52657,P20618,Q13200,P62333,P60900,Q15370,P25787,P25788,P25789,P25786,Q9NP79,P18858,P28066,Q9UN37,O00233,P28074,P62195,P49720,P61289,P62826,P49917,P63208,O75832,Q99436,Q96PU5,Q9BXS5,Q9NZZ3,Q15369,P62191,P39748,O75351 32
Synthesis of ip2 ip and ins in the cytosol 0.7592810257513416 1.8093873531588127 0.0703908465468265 1.0 0.847638079324235 4 Q96PE3 1
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.6489692982859913 1.7975644677470002 0.0722460533636986 1.0 0.847638079324235 17 Q9UHV9,P50991,P48643,P61758,P78371,Q9BUF5,P04350,P40227,Q99471,P17987,Q9NQP4,P50990,Q99832,P68371 14
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.756460674157309 1.797074045113687 0.0723238655419131 1.0 0.847638079324235 4 Q00534,P24941,P06400 3
Molybdenum cofactor biosynthesis 0.6875499451945515 1.7823806213637718 0.074687183465977 1.0 0.847638079324235 6 O96007,Q96EN8 2
Methionine salvage pathway 0.7196930087231662 1.7804894835882965 0.0749958888809847 1.0 0.847638079324235 5 Q9BV20,P17174,Q9BV57 3
Metabolism of nitric oxide nos3 activation and regulation 0.6126563126030093 1.771652607760089 0.0764522411722024 1.0 0.847638079324235 8 O00401,Q9Y314,O75608 3
Eukaryotic translation elongation 0.5749528344244123 1.734261242180074 0.0828717410135002 1.0 0.847638079324235 79 P62244,P62241,P62899,P62280,P50914,P60866,P32969,P05386,P46776,P62917,P62906,P62861,P46781,P18621,P35268,P29692,P39019,P62851,P62424,P62269,P25398,P62249,P61254,P30050,P40429,P63220,Q02878,P61353,P05387,P46782,P46778,P83731,P62273,P62266,P61927,P46777,P84098,P62829,P13639,P63173,P62263,P61513,P08708,P62081,P05388,P62854,P62847,P42766,P15880,P08865,Q05639,P24534,P62841,P62701,P26373,P62277,P18124,P62753,P62888,P62913,Q9Y3U8,P61247,P62857,P23396,P26641,P62750 66
Response of eif2ak4 gcn2 to amino acid deficiency 0.5746592933130943 1.731899323215038 0.0832914892809317 1.0 0.847638079324235 79 P62244,P62241,P62899,P62280,P50914,P60866,P32969,P05386,P08243,P46776,P62917,P62906,P62861,P46781,P18621,P35268,P39019,P62851,P62424,P62269,P25398,P62249,P61254,P30050,P40429,P63220,Q02878,P61353,P05387,Q92616,P46782,P46778,P83731,P62273,P62266,P61927,P46777,P20042,P84098,P62829,P41091,P63173,P62263,P61513,P08708,P62081,P05388,P05198,P62854,P62847,P42766,P15880,P08865,P62841,P62701,P62277,P26373,P61247,P18124,P62753,P62888,P62913,Q9Y3U8,P62857,P23396,P62750 66
Formation of tubulin folding intermediates by cct tric 0.6237651051859369 1.729484429541735 0.0837224308387525 1.0 0.847638079324235 13 P50991,P48643,P78371,Q9BUF5,P04350,P40227,P17987,P50990,Q99832,P68371 10
Vxpx cargo targeting to cilium 0.610137705867134 1.7149728200275738 0.0863502102664341 1.0 0.847638079324235 10 Q9NV70,P18085 2
Scf skp2 mediated degradation of p27 p21 0.665809999276378 1.7115116933603105 0.0869866944315664 1.0 0.847638079324235 42 P24941,P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P20248,P35998,Q9UL46,Q13309,P25788,P25789,P25787,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P63208,P11802,P55036,P62191 34
Neddylation 0.5698832484271572 1.693465212003887 0.0903669511873102 1.0 0.847638079324235 79 Q9H9Q2,P28070,Q9BT78,Q8TBC4,P20618,O43242,Q96GG9,P43686,O14818,Q13200,O00487,P62333,Q13564,Q9UNM6,Q9BW61,P28072,Q9NX08,P60900,Q5TAQ9,Q15008,Q9UBW8,P35998,Q15370,Q92905,Q9UL46,Q7L5N1,Q13309,P25787,P25788,P25789,O75147,P25786,P28066,Q14145,O00233,P17980,P28074,P62195,P49720,P61289,Q9BTE7,P61962,P63208,O75832,O00231,O00232,Q99436,Q86VP6,Q9H0A8,Q13098,Q9NZJ0,P61081,Q15369,P55036,Q16531,Q9UNS2,P62191 57
Downregulation of tgf beta receptor signaling 0.601687763713092 1.6904489129347449 0.090942104069734 1.0 0.847638079324235 9 Q96PU5,P62136,Q9UNE7,P36873,Q9Y5K5,Q9Y3F4,Q9Y4E8,O14980 8
Platelet sensitization by ldl 0.6649149222062285 1.674205747148319 0.0940901703903298 1.0 0.847638079324235 6 P30153,Q06124,Q14738,Q16539 4
Response of eif2ak1 hri to heme deficiency 0.7283707865168609 1.6738434408186826 0.0941613722940024 1.0 0.847638079324235 4 P08243,P41091,P05198 3
Nod1 2 signaling pathway 0.6057509308775177 1.670598098666494 0.0948010883066712 1.0 0.847638079324235 11 Q13404,P52564,P42575 3
Synthesis of diphthamide eef2 0.7266853932584303 1.6664174876497595 0.0956302900720957 1.0 0.847638079324235 4 Q9H2P9,Q9BZG8,Q9BQC3 3
G1 s specific transcription 0.6121315953380353 1.666208921589707 0.0956718096315549 1.0 0.847638079324235 13 P31350,P00374,P04183,Q99741,P06493,P12004,Q9Y619,Q5TKA1 8
Post chaperonin tubulin folding pathway 0.5986533807956641 1.6526421065632204 0.0984037232352073 1.0 0.847638079324235 10 Q99426,O75347,Q9BUF5,P04350 4
Negative regulation of notch4 signaling 0.6535556751894149 1.637258379262908 0.1015764934761207 1.0 0.847638079324235 40 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,Q9Y6A5,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P63208,P55036,P62191 31
Cell cycle checkpoints 0.2832909488162194 1.631454146240752 0.1027945277143365 1.0 0.847638079324235 168 Q8N2W9,P63167,P24941,P28070,Q9UBD5,P31946,P20618,O43242,P43686,O14818,Q13200,O00487,P62333,Q9Y6G9,Q8NBT2,Q9Y619,Q9UNM6,Q96EA4,Q9BX63,P15927,Q99741,Q99640,P28072,P20248,O43929,Q15008,P35998,P33991,P42771,P60900,O43684,Q9NXR7,Q9UL46,P25787,P25788,P25789,Q13409,P25786,Q8N0S6,P28066,Q04917,O00233,Q9P258,P17980,P51530,P06493,P28074,P62195,P55735,P49720,P61289,O00231,O75832,P30307,O00232,Q9H900,Q99436,Q15691,P62258,Q9UQ84,Q9HBM1,P55036,P35250,O96017,Q9Y266,P62191,P27694,O43237 68
Nonsense mediated decay nmd 0.5087805996192086 1.6205491753605068 0.1051143598354604 1.0 0.847638079324235 89 P62244,P62241,P62899,P62280,P50914,P60866,P32969,P05386,P46776,P62917,P62906,P62861,P46781,P18621,P35268,P62495,P39019,P62851,P62424,P62269,P25398,P62249,P61254,P30050,P40429,P30153,P63220,Q02878,P61353,P05387,Q9HAU5,P46782,P46778,P15170,P83731,P62273,P62266,P61927,P46777,P84098,P62829,P63173,P62263,P61513,P08708,P62081,P05388,P62854,Q8ND04,P62847,P42766,P15880,P08865,P62841,P62701,P62277,P26373,P62913,P63151,P62753,Q9Y5S9,P18124,Q9Y3U8,P62888,P61247,P62857,P23396,P62750 68
Regulation of runx3 expression and activity 0.6505245583374254 1.619961016309069 0.1052406513434096 1.0 0.847638079324235 39 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P42771,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 30
Tp53 regulates transcription of cell death genes 0.58020599406468 1.6186621062662738 0.1055199843265906 1.0 0.847638079324235 7 Q92597,P42575 2
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.5781817237800569 1.6076426603312646 0.1079134633656946 1.0 0.847638079324235 7 P30153,P49643,P06400,P49642 4
Glutathione conjugation 0.6080288567673711 1.6073288353144914 0.1079822520320581 1.0 0.847638079324235 15 P28161,P14550,P78417,Q8WUX2,O75223,O43708,P10768,P21266,P48507 9
Nucleotide biosynthesis 0.6011714523542588 1.6063818802591656 0.1081900296302182 1.0 0.847638079324235 13 P22234,P22102,P30520,Q06203,P11172,P12268,P20839,P49915,P30566 9
Cross presentation of soluble exogenous antigens endosomes 0.6438450850194881 1.5843736734495042 0.113108709260794 1.0 0.847638079324235 37 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 29
Degradation of axin 0.6438450850194881 1.5843736734495042 0.113108709260794 1.0 0.847638079324235 37 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 29
Dectin 1 mediated noncanonical nf kb signaling 0.6430810406965938 1.5756761047888557 0.1151004670527793 1.0 0.847638079324235 42 P28070,Q8TBC4,P20618,O43242,P43686,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P63208,P61081,O15111,P55036,P62191 33
Akt phosphorylates targets in the cytosol 0.6746949657933656 1.5738640357911788 0.1155188859289046 1.0 0.847638079324235 5 P49815,Q96B36,P49840 3
Degradation of dvl 0.6390349253999166 1.5538792979651967 0.1202132106974356 1.0 0.847638079324235 38 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 29
Tgf beta receptor signaling activates smads 0.5871873893293572 1.5492536856468513 0.1213207485138929 1.0 0.847638079324235 12 Q96PU5,Q13485,P61081,Q9Y5K5,Q9Y3F4,Q9Y4E8 6
Cdt1 association with the cdc6 orc origin complex 0.6368821836878938 1.5397160893081854 0.1236295732255285 1.0 0.847638079324235 43 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9Y619,Q9UNM6,P28072,O43929,P60900,Q99741,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,O00232,P55036,P62191,Q9UBD5 34
Metabolism of polyamines 0.6368351560721538 1.5381980140588982 0.1240002064288845 1.0 0.847638079324235 40 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P52788,P28072,P60900,P35998,P19623,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 31
Budding and maturation of hiv virion 0.5789061906443499 1.524057734782596 0.127494289456467 1.0 0.847638079324235 11 Q9NZZ3,Q96PU5,Q9NP79,O75351 4
Interleukin 6 family signaling 0.6939460076975484 1.5215581931247726 0.1281198196503523 1.0 0.847638079324235 4 Q06124 1
Interleukin 6 signaling 0.6939460076975484 1.5215581931247726 0.1281198196503523 1.0 0.847638079324235 4 Q06124 1
G1 s dna damage checkpoints 0.6320099068855537 1.5103999191361197 0.1309414092591772 1.0 0.847638079324235 43 P24941,P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P42771,P60900,P20248,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191,O96017 33
Spry regulation of fgf signaling 0.5592611621201301 1.5043143811555026 0.1325004378899901 1.0 0.847638079324235 7 P62993,P27361,Q06124,P30153,P28482 5
Negative regulation of fgfr4 signaling 0.5592611621201301 1.5043143811555026 0.1325004378899901 1.0 0.847638079324235 7 P62993,P27361,Q06124,P30153,P28482 5
Negative regulation of fgfr2 signaling 0.5592611621201301 1.5043143811555026 0.1325004378899901 1.0 0.847638079324235 7 P62993,P27361,Q06124,P30153,P28482 5
Negative regulation of fgfr1 signaling 0.5592611621201301 1.5043143811555026 0.1325004378899901 1.0 0.847638079324235 7 P62993,P27361,Q06124,P30153,P28482 5
Negative regulation of fgfr3 signaling 0.5592611621201301 1.5043143811555026 0.1325004378899901 1.0 0.847638079324235 7 P62993,P27361,Q06124,P30153,P28482 5
Cdc6 association with the orc origin complex 0.6277688864842907 1.495059319615499 0.1348989614770592 1.0 0.847638079324235 6 O43929,Q9Y619,Q9UBD5 3
Cyclin a cdk2 associated events at s phase entry 0.6274328740920337 1.4937307648550986 0.1352460040465237 1.0 0.847638079324235 47 P24941,P28070,P20618,P06400,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P20248,P35998,Q9UL46,Q13309,P25787,P25789,P25788,Q5TKA1,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P63208,P11802,P55036,P62191 36
Tnfr2 non canonical nf kb pathway 0.6291090664661035 1.4929452062318491 0.1354515304677515 1.0 0.847638079324235 43 P28070,Q8TBC4,P20618,O43242,P43686,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P63208,P61081,O15111,P55036,P62191 33
Stabilization of p53 0.6265167766044386 1.4764110871116631 0.1398335681317495 1.0 0.847638079324235 41 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P42771,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191,O96017 31
Hedgehog ligand biogenesis 0.6261736383519846 1.476300407427899 0.1398632648279154 1.0 0.847638079324235 39 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 29
Nicotinamide salvaging 0.6500644626219422 1.4597596412727016 0.1443561440522436 1.0 0.847638079324235 5 P43490,Q9BQG2,Q8NCW5 3
Wnt ligand biogenesis and trafficking 0.6792404491751978 1.456184048402855 0.1453417479780512 1.0 0.847638079324235 4 Q9UBQ0,O60493 2
Synthesis of udp n acetyl glucosamine 0.6486747836791393 1.453306450444632 0.1461386871423251 1.0 0.847638079324235 5 O95394 1
Tp53 regulates transcription of cell cycle genes 0.5884025496958635 1.4489508376083116 0.1473513124332977 1.0 0.847638079324235 18 P24941,Q99873,Q9UIV1,Q86X55,P06493,O75175,P12004,P30307 8
Aggrephagy 0.5823599909614813 1.4486780657988367 0.1474275087082195 1.0 0.847638079324235 16 Q99497,Q9BUF5,Q13409,Q13404,O43237 5
Activation of bad and translocation to mitochondria 0.5531496062992127 1.4477463014766332 0.1476880156039994 1.0 0.847638079324235 8 Q04917,P63104,Q9Y3B8,P31751,P31946,P62258,P27348 7
Regulation of ras by gaps 0.6209821069427491 1.444200550000312 0.1486825702483647 1.0 0.847638079324235 40 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P21359,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 30
Regulation of runx2 expression and activity 0.6203376824581558 1.4415456660863395 0.1494305858019327 1.0 0.847638079324235 44 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,Q13309,P25788,P25789,P25787,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P63208,Q9UNE7,P55036,P62191 32
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.5628400352725689 1.4358940044474762 0.1510325048032403 1.0 0.847638079324235 11 Q04917,P31946,P62258,P06493,O96017,P27348,P30307 7
Regulation of pten stability and activity 0.6196186949592353 1.4358512165821198 0.1510446824022024 1.0 0.847638079324235 43 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q15008,P19784,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P67870,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,O00232,Q9UNE7,P55036,P62191 34
Developmental biology 0.3287473480520795 1.4350642300086156 0.1512687954102749 1.0 0.847638079324235 287 P62899,Q92796,P18621,P60660,P40763,P23528,P35998,P63220,P52564,Q00169,P28066,O00233,O43639,P08708,P05388,O75832,A7E2V4,Q9BUF5,Q00535,P61586,Q15369,P55036,P61160,P62857,O15145,P17612,Q9UNM6,P50552,Q13485,P30050,Q15370,P26038,P25787,P25788,P25789,P62273,Q01518,P62829,Q14118,P59998,P07737,P49720,P62854,Q96EK7,P62753,Q9Y5S9,Q9Y3U8,O00401,P62280,P09497,P60866,P05386,O43242,O14818,O00487,P39019,P28072,P25398,P60900,P62249,P19784,Q86X55,P83731,P61927,P46777,P04350,P28074,P61289,P62847,P68371,P62993,P15880,P11802,P08865,Q7Z406,O75928,P62888,P23396,P62750,P62487,P62244,P62241,P24941,P50914,P28070,P32969,P35080,P20618,P46776,Q06124,P43686,P46781,Q13200,P62495,P62333,Q15334,Q92747,Q8N8S7,Q9UL46,P25786,Q9HAU5,P15170,P27361,P17980,P84098,P15311,P07384,P62195,P42766,O00231,O00232,Q99436,O00560,Q96S59,P62841,P62701,P62277,P62913,P62191 119
Orc1 removal from chromatin 0.6098926391024443 1.4309063976655076 0.1524570432499432 1.0 0.847638079324235 54 P24941,P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9Y619,Q9UNM6,P28072,O43929,P60900,P20248,Q99741,P35998,Q15008,Q9UL46,Q13309,P25787,P25789,P25788,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,O00232,P63208,P55036,P62191,Q9UBD5 39
Metabolic disorders of biological oxidation enzymes 0.6142948710890807 1.429697699408656 0.1528038008492229 1.0 0.847638079324235 6 P23526,P48507 2
Dna replication initiation 0.6142878256530102 1.429663483653486 0.1528136255683128 1.0 0.847638079324235 6 Q9NR33,P49642 2
Processive synthesis on the lagging strand 0.5741666871057204 1.4210635958901978 0.1552982720005284 1.0 0.8567492069083705 15 P49643,P15927,Q15054,P51530,P49642,P12004,P39748,P18858 8
Maturation of sars cov 2 nucleoprotein 0.5436434661393612 1.4186483147852105 0.1560015725933639 1.0 0.8567492069083705 7 P49840,Q8IXQ6,Q99873,Q96SB4 4
E2f mediated regulation of dna replication 0.5696463105583383 1.4144324924308136 0.1572349554812606 1.0 0.858514576412117 14 P49643,O43929,P06400,P30153,P06493,P49642,Q9Y619,Q9UBD5 8
Dna damage reversal 0.6106061672006724 1.411778971389901 0.1580150520879701 1.0 0.858514576412117 6 P16455,Q8N9N2,Q9C0B1 3
Asymmetric localization of pcp proteins 0.6145823783006177 1.4102113526701787 0.1584772846211728 1.0 0.858514576412117 38 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 29
Mismatch repair 0.5649871930781161 1.4077416730892132 0.159207577156879 1.0 0.858514576412117 13 P20585,P15927,Q9UQ84,Q15054,P43246,P12004,P27694,P18858 8
Generation of second messenger molecules 0.6094952213416672 1.406380523076078 0.1596111606850696 1.0 0.858514576412117 6 P50552 1
Diseases of signal transduction by growth factor receptors and second messengers 0.2655038504810275 1.3962936155640857 0.1626260955886769 1.0 0.8714303990034763 158 P28070,P31946,P20618,P41240,Q06124,O43242,P43686,O14818,Q99956,Q96PU8,O95352,O00487,Q13200,P62333,O43252,Q9UNM6,P49840,P49815,Q63HN8,P40763,P28072,P60900,Q13485,P35998,P26038,Q9UL46,P10398,P25787,P25788,P25789,Q16543,Q9HC35,P25786,P49407,Q32MZ4,P28066,Q96B36,O00233,P30086,P21359,P27361,P17980,P56545,P28074,Q07866,P62195,P49720,P61289,P63208,O75832,O00231,P62993,Q99436,Q13363,P62753,O15111,P55036,P62191,P67936,P26641,P62487 61
Nicotinate metabolism 0.604978622585884 1.3844253167682572 0.1662282614035199 1.0 0.8719925748686403 6 P43490,Q9BQG2,Q8NCW5 3
Assembly and cell surface presentation of nmda receptors 0.5534099997784525 1.3840394783947971 0.1663463668155467 1.0 0.8719925748686403 11 Q92796,Q9BUF5 2
Bmal1 clock npas2 activates circadian gene expression 0.7839089838830491 1.374532160085764 0.1692765332085899 1.0 0.8747986883115474 3 P43490 1
Tcr signaling 0.6013264971705207 1.3674992235703682 0.1714688804669015 1.0 0.8747986883115474 53 P28070,P20618,P41240,P43686,O43242,O14818,Q13200,P62333,O00487,Q13404,Q9UNM6,P50552,Q8N8S7,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,O95999,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,P63208,O15111,P55036,P62191,P49427 37
Sema4d induced cell migration and growth cone collapse 0.5335244071532906 1.363014076755252 0.1728780742287639 1.0 0.8747986883115474 7 P60660,Q7Z406 2
Uptake and actions of bacterial toxins 0.5401841246406751 1.3540737166355403 0.1757128605829729 1.0 0.8747986883115474 9 Q16881,Q02750,P08238,P13639,O14733,P52564 6
Signaling by csf3 g csf 0.536090747237916 1.3539951429396313 0.1757379273015913 1.0 0.8747986883115474 8 Q15369,Q06124,P40763,Q15370 4
Protein methylation 0.5313892402446397 1.3512657952569351 0.1766103047879621 1.0 0.8747986883115474 7 O60678,P15880 2
Interleukin 20 family signaling 0.7772714581140022 1.348150678548497 0.1776099242957161 1.0 0.8747986883115474 3 Q06124 1
Degradation of gli1 by the proteasome 0.6048323974359104 1.3468144032445033 0.178040014733829 1.0 0.8747986883115474 42 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P63208,P55036,P62191,P17612 31
Cyclin a b1 b2 associated events during g2 m transition 0.552636987406572 1.3397041033834012 0.1803415629832447 1.0 0.8805528693925629 13 P24941,P20248,Q9Y570,P06493,P30307 5
Defective cftr causes cystic fibrosis 0.6022384153322231 1.3319102035912325 0.1828896976971783 1.0 0.8832459043291888 41 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,O75477,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 30
Abc transporter disorders 0.6022384153322231 1.3319102035912325 0.1828896976971783 1.0 0.8832459043291888 41 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,O75477,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 30
Signaling by pdgf 0.5387523847078546 1.3244391515471206 0.185357239077534 1.0 0.8832459043291888 10 P46109,Q06124,O43639 3
Downstream signal transduction 0.5387523847078546 1.3244391515471206 0.185357239077534 1.0 0.8832459043291888 10 P46109,Q06124,O43639 3
Regulation of bach1 activity 0.6483146067415865 1.3183529142220387 0.187385535230264 1.0 0.884011495106229 4 P63208,Q9BX63,Q13309 3
Interleukin 1 signaling 0.5960472099217708 1.31401691751242 0.1888405111637923 1.0 0.8852297828774426 50 P09429,P28070,P51617,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q13404,Q9UNM6,P28072,P60900,P35998,Q9UL46,P52564,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,P63208,O15111,P55036,P62191 35
Inositol phosphate metabolism 0.5280783999559693 1.309901099133016 0.1902292952804991 1.0 0.8885710503233842 8 Q96PE3 1
Endosomal sorting complex required for transport escrt 0.532523951532238 1.290155580881752 0.1969966451387481 1.0 0.903553679215212 10 Q9NZZ3,Q9NP79,O75351 3
Rho gtpases activate rocks 0.5321991196037789 1.2883675630078488 0.1976180445114037 1.0 0.903553679215212 10 P60660,Q7Z406,P23528 3
Synthesis of gdp mannose 0.7621091006060189 1.287898661779638 0.197781241394098 1.0 0.903553679215212 3 Q96IJ6 1
Displacement of dna glycosylase by apex1 0.7616091392824779 1.2859126564975714 0.1984735460906712 1.0 0.903553679215212 3 P27695 1
Clec7a dectin 1 signaling 0.5838333198230752 1.2824149053705305 0.1996971382151822 1.0 0.9059742372701556 56 P28070,Q8TBC4,P20618,O43242,P43686,O14818,Q13200,P62333,O00487,Q13404,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,Q14790,P17980,O95999,P28074,P62195,P49720,O43865,P61289,O00231,O75832,Q99436,P63208,P61081,O15111,P55036,P62191,P49427 38
Gap junction assembly 0.610155070597664 1.2740891982062623 0.202631806132721 1.0 0.9100670333618796 5 Q9BUF5,P04350 2
Transport of connexons to the plasma membrane 0.610155070597664 1.2740891982062623 0.202631806132721 1.0 0.9100670333618796 5 Q9BUF5,P04350 2
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.5863335723531258 1.272404208741761 0.2032295394681562 1.0 0.9100670333618796 53 Q13347,P62241,P62244,P62280,P60842,P60866,P46781,O75821,P39019,P62851,P25398,O15372,P62249,P63220,Q15056,Q7L2H7,P46782,P62273,Q14240,O00303,P62266,P20042,Q9UBQ5,P41091,P62263,O75822,P08708,P62081,P62847,P05198,P62854,P15880,P62841,P06730,P62277,P62701,P08865,P61247,P62753,P62857,P23396 41
Condensation of prometaphase chromosomes 0.5287060778486332 1.2691410877649232 0.2043907481742515 1.0 0.9100670333618796 10 Q15003,Q9BPX3,P14635,P19784,P67870,P06493,O95067 7
Detoxification of reactive oxygen species 0.5235103367675974 1.2623084424831177 0.2068378199835872 1.0 0.9100670333618796 9 P30041,Q16881,P30044 3
Negative regulation of mapk pathway 0.5385152446783248 1.2618870164643616 0.2069894445572453 1.0 0.9100670333618796 13 P30086,P27361,P31946,P30153,Q99956,P10398,Q14738,P30154,P53041,P28482 10
Unwinding of dna 0.5232545358637866 1.2609005968279137 0.2073446631529201 1.0 0.9100670333618796 9 P25205,Q9BRT9,P33991,Q9Y248,Q9BRX5 5
Auf1 hnrnp d0 binds and destabilizes mrna 0.5899646202847514 1.2581742054072618 0.2083287614489859 1.0 0.9100670333618796 42 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 29
Translation 0.292459867200073 1.2565106631957983 0.208930882307023 1.0 0.9100670333618796 224 Q9H2U2,P62899,P60842,Q15046,P18621,O43776,P49458,P41250,P49770,P23381,P63220,P05387,Q15181,P62266,Q9UBQ5,P63173,P62263,P61513,P08708,P62081,P05388,P05198,O76094,Q05639,P24534,P62857,Q9UHB9,Q96A35,Q13155,P35268,P09132,P29692,O15372,P61254,P30050,P13798,Q02878,P67812,P61353,O60841,Q7L2H7,P46782,Q9UI30,P62273,P62829,P62854,Q14232,Q9NR50,P62753,Q9Y3U8,O43324,Q9NSD9,P62280,P60866,P05386,P39019,P51571,P25398,P62249,Q15056,P83731,P61927,P46777,P62847,P15880,P08865,P06730,P26639,P62888,P23396,P26641,P49591,P62750,P62244,P62241,P54136,P50914,P54577,P32969,P46776,P46781,P62495,P15170,Q9BYD3,Q14240,O00303,P20042,P84098,P41091,P14868,P13639,Q13144,Q12904,O75822,P55010,P42766,P62841,P62701,P62277,P62913,P61247,P37108 102
Irak1 recruits ikk complex 0.7525975849480692 1.2501297181083892 0.2112521653876711 1.0 0.916238297305065 3 Q13404,P51617 2
Cytosolic trna aminoacylation 0.5646836712228858 1.2448818888427942 0.2131751691800003 1.0 0.916238297305065 23 Q9NSD9,P54136,P54577,P26640,Q15046,Q13155,O43776,P56192,P41250,P23381,P41252,P49589,Q9P2J5,Q15181,P14868,Q12904,P26639,P49591,O43324 19
Fceri mediated nf kb activation 0.5855585979867179 1.24027429651683 0.2148739560983679 1.0 0.9172434494599614 48 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q13404,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,O95999,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,P63208,O15111,P55036,P62191,P49427 34
Sulfur amino acid metabolism 0.5267240043297161 1.237145912179292 0.2160329174171598 1.0 0.9172434494599614 11 P23526,Q9BV20,Q9BV57,P25325,P17174 5
Gab1 signalosome 0.6299281711525653 1.236366528933869 0.2163223517906396 1.0 0.9172434494599614 4 P62993,Q06124 2
Synthesis of pips at the early endosome membrane 0.6007219450632957 1.2301825512516258 0.2186287524060413 1.0 0.921945705940595 5 Q13614 1
Carnitine metabolism 0.6006237877778074 1.229725830151181 0.2187997907760426 1.0 0.921945705940595 5 O43772,O00763 2
Cyclin d associated events in g1 0.5319354385786822 1.2256523794404584 0.2203295176561415 1.0 0.9235127688563004 13 P24941,Q00534,P11802,P42771,P06400,P63151,P30153,P30154,Q13309,P63208 10
Cytosolic iron sulfur cluster assembly 0.5153746274406528 1.2175429910784934 0.2233976898003074 1.0 0.9261671470910908 9 P53384,Q9BX63,Q6FI81,Q9Y5Y2,Q96T76,P28340,O76071 7
Formation of xylulose 5 phosphate 0.7441729851165466 1.2167088198274332 0.2237150221494677 1.0 0.9261671470910908 3 P14550,Q00796 2
Prolactin receptor signaling 0.7437279020779743 1.214944205305898 0.2243873722576632 1.0 0.926250199435703 3 P63208 1
Srp dependent cotranslational protein targeting to membrane 0.4414505028146997 1.203184943455027 0.2289047600669171 1.0 0.936728412953955 93 P62244,P62241,P62899,P62280,P50914,P60866,P32969,P05386,P46776,P62917,P62906,P62861,P46781,P18621,P60059,P35268,P09132,P39019,P51571,P49458,P62851,P62424,P62269,P25398,P62249,P61254,P30050,P40429,P63220,Q02878,P67812,P61353,P05387,P46782,P46778,P83731,P62273,P62266,P61927,P46777,P84098,P62829,P63173,P62263,P61513,P08708,P62081,P05388,P62854,P62847,P42766,O76094,P15880,P08865,P62841,P62701,P62277,P26373,P61247,P18124,P62753,P62888,P62913,Q9Y3U8,P37108,P62857,P23396,Q9UHB9,P62750 69
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.5664110755182051 1.1967628517222688 0.2313990013939739 1.0 0.9380439319665868 6 Q13404,P51617 2
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.5115124854690989 1.1963042270244435 0.2315778598276325 1.0 0.9380439319665868 9 O75175,P30307 2
The role of gtse1 in g2 m progression after g2 checkpoint 0.5760144909773509 1.194838294228575 0.2321502153871129 1.0 0.9380439319665868 51 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P04350,P28074,P06493,P62195,P49720,P61289,O00231,O75832,Q99436,P68371,Q15691,Q9BUF5,P55036,P62191 34
Signaling by notch4 0.5792922772199613 1.1944099740643208 0.2323176371580411 1.0 0.9380439319665868 44 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,Q9Y6A5,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P63208,P55036,P62191 31
Pentose phosphate pathway 0.5140622592844989 1.188589575155225 0.2346012121268592 1.0 0.9383683742424572 10 P11908,Q9Y315,P37837,P49247,O95336,P60891 6
Fructose metabolism 0.7361326144462452 1.1848508290002662 0.2360764315920511 1.0 0.9383683742424572 3 Q00796 1
Downstream signaling events of b cell receptor bcr 0.574364681712416 1.1718618438782051 0.2412525283505506 1.0 0.9383683742424572 48 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,O95999,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,P63208,P05771,O15111,P55036,P62191 33
Infection with mycobacterium tuberculosis 0.5238967355764591 1.1623353764277726 0.2450992620787371 1.0 0.9383683742424572 14 P27361,Q63HN8,P06733,P00558 4
Response of mtb to phagocytosis 0.5238967355764591 1.1623353764277726 0.2450992620787371 1.0 0.9383683742424572 14 P27361,Q63HN8,P06733,P00558 4
Transcriptional regulation by runx2 0.5651096046430426 1.1620899701420986 0.2451989211072913 1.0 0.9383683742424572 56 P28070,P20618,P06400,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,Q13485,P35998,Q9UL46,Q13309,P25788,P25789,P25787,P25786,P28066,O00233,P27361,P17980,P17931,P28074,P06493,P62195,P49720,P61289,O00231,O75832,Q99436,P63208,P11802,Q9UNE7,P55036,P62191 38
Mapk family signaling cascades 0.4197814239688496 1.1586920125650015 0.2465817477915599 1.0 0.9383683742424572 96 P28070,Q92796,P31946,P20618,P41240,Q06124,O43242,P43686,O14818,Q99956,Q13200,O00487,P62333,Q9UNM6,Q15334,P28072,P60900,P35998,Q9UL46,P10398,P25787,P25788,P25789,P25786,P49407,P28066,O00233,O75608,P30086,P21359,P27361,P17980,P28074,P06493,P62195,P53041,P49720,P61289,O00231,O75832,Q99436,P62993,Q96S59,P55036,P62191,P17612 46
Rrna processing in the mitochondrion 0.5835627206333768 1.1504284473821889 0.2499674490357029 1.0 0.9383683742424572 5 Q8WVM0,Q9BQ52 2
Ub specific processing proteases 0.4612877525547165 1.1451160120088006 0.2521611034689794 1.0 0.9383683742424572 88 P28070,P20618,O43242,P43686,O14818,Q13200,Q9Y5T5,O00487,P62333,P54578,Q9UNM6,Q9Y4E8,P28072,P60900,P20248,Q13485,P35998,Q70CQ2,Q9UL46,P25787,Q13309,P25789,P25788,P25786,P49407,P28066,O00233,O60493,Q96FW1,P17980,P51784,P28074,P62195,P49720,P61289,O75528,O00231,O75832,Q99436,Q9UPT9,Q9NZL9,P55036,P62191 43
Inactivation of csf3 g csf signaling 0.5552847922513348 1.1427100547944316 0.2531589937398775 1.0 0.9383683742424572 6 Q15369,Q15370 2
Uptake and function of diphtheria toxin 0.6087078651685472 1.1419359734135692 0.2534806343266482 1.0 0.9383683742424572 4 P13639,P08238,Q16881 3
Pi5p regulates tp53 acetylation 0.5802892200566485 1.1352407604126675 0.2562744555136036 1.0 0.9383683742424572 5 P52564,Q13526,P48426 3
Regulation of localization of foxo transcription factors 0.5528386734120345 1.1308415320866196 0.2581217957633135 1.0 0.9383683742424572 6 P63104,Q9Y3B8,P31751,P31946,P27348 5
Suppression of apoptosis 0.5514077811063869 1.1239019208138452 0.2610546363786226 1.0 0.9383683742424572 6 P27361,Q63HN8 2
Dna replication pre initiation 0.5415129286090974 1.1183145015747435 0.2634326955407156 1.0 0.9383683742424572 65 P24941,P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9Y619,Q9UNM6,P49643,P15927,P28072,O43929,P60900,Q99741,Q15008,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,Q9NR33,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,O00232,P55036,P62191,P49642,P27694,Q9UBD5 41
Estrogen dependent nuclear events downstream of esr membrane signaling 0.60337078651686 1.118247923932764 0.2634611214499758 1.0 0.9383683742424572 4 P28482,P27361,O14980 3
G2 m checkpoints 0.4091063485640756 1.1104947843228874 0.2667858743908811 1.0 0.9383683742424572 97 Q8N2W9,P24941,P28070,P31946,P20618,O43242,P43686,O14818,Q13200,O00487,P62333,Q9Y619,Q9UNM6,Q9BX63,P15927,Q99741,Q99640,P28072,O43929,P60900,Q15008,P35998,Q9NXR7,Q9UL46,P25787,P25788,P25789,P25786,P28066,Q04917,O00233,P17980,P51530,P06493,P28074,P62195,P49720,P61289,O00231,O75832,P30307,O00232,Q99436,P62258,Q9UQ84,P55036,P35250,O96017,P62191,P27694,Q9UBD5 51
Abc family proteins mediated transport 0.5622924663212507 1.1099508717971194 0.2670201972072923 1.0 0.9383683742424572 51 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,O75477,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P20042,P17980,P41091,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,P05198,Q9NRK6,P55036,P62191 34
Intracellular signaling by second messengers 0.3910275127073568 1.1099181328745058 0.2670343059691351 1.0 0.9383683742424572 100 P28070,P51617,P20618,Q99460,Q06124,O43242,P43686,O14818,Q13200,O00487,P30154,P62333,Q9UNM6,P49840,P49815,P28072,P60900,P35998,Q15008,P19784,Q9UL46,P30153,P29590,P25787,P10644,P25788,P25789,P25786,P28066,Q96B36,O00233,P27361,P17980,P67870,P28074,P62195,P49720,P61289,O43865,O00231,Q92995,O75832,P62993,O00232,Q99436,Q9UNE7,O15111,P55036,Q14738,P62191,P48426,P17612,Q8TBX8 53
Fc epsilon receptor fceri signaling 0.546372765220423 1.1069420858378407 0.2683189684207048 1.0 0.9383683742424572 62 P28070,P20618,P43686,O43242,O14818,O14733,Q13200,O00487,P62333,Q13404,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P27361,P17980,O95999,P28074,P62195,P49720,O43865,P61289,O00231,O75832,Q99436,P62993,P63208,O15111,P55036,P62191,P49427 38
Cellular response to hypoxia 0.5633720934842783 1.0999245380697058 0.2713650023489831 1.0 0.9383683742424572 43 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q15370,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,Q15369,P55036,P62191 31
Metabolism of ingested semet sec mesec into h2se 0.9508702975856276 1.095452131167109 0.273318606010922 1.0 0.9383683742424572 2 Q96I15 1
Hedgehog on state 0.5625120915938947 1.0948539218977325 0.2735806386875896 1.0 0.9383683742424572 43 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P49407,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 30
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.4841465704927287 1.0914172358554135 0.2750893316582548 1.0 0.9412695203728236 7 Q13404,P51617 2
Regulation of hmox1 expression and activity 0.5593840987347586 1.081002766612131 0.2796958829739739 1.0 0.9486621026217948 48 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,Q9BX63,P28072,P60900,P19784,Q15008,P35998,Q9UL46,Q13309,P25787,P25789,P25788,P25786,P28066,O00233,Q14145,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,O00232,P63208,P55036,P62191 36
Interleukin 1 family signaling 0.5515887385578737 1.0761056816024364 0.281879994967058 1.0 0.9486621026217948 56 P09429,P28070,P51617,P20618,Q06124,P43686,O43242,O14818,Q13200,P62333,O00487,Q13404,Q9UNM6,P40763,P28072,P60900,P35998,Q9UL46,P52564,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,P63208,O15111,P55036,P62191 37
Signaling by the b cell receptor bcr 0.5531782008994683 1.064575414382022 0.2870681104187502 1.0 0.9562299550125606 53 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,O95999,P28074,P62195,P49720,O43865,P61289,O00231,O75832,Q99436,P62993,P63208,P05771,O15111,P55036,P62191 35
Apoptotic factor mediated response 0.4871307978292895 1.062618763818815 0.2879548742386242 1.0 0.9562299550125606 9 Q96GX9,Q16611,P42771,P27361,P28482,P55210 6
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.5643950719188215 1.0616871797572034 0.2883777213240428 1.0 0.9562299550125606 5 P20248,P06493 2
Apc c mediated degradation of cell cycle proteins 0.5429918548181225 1.060178780280065 0.2890632728652726 1.0 0.9562299550125606 60 P24941,P28070,P20618,P06400,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P20248,P35998,Q9UL46,O43684,Q13309,P25787,P25789,P25788,P25786,P28066,O00233,P17980,P28074,P06493,P62195,P49720,P61289,O00231,O75832,Q99436,P63208,P55036,P62191 36
Plasma lipoprotein assembly 0.5897108290730024 1.0577886118648745 0.290151825844255 1.0 0.9562299550125606 4 Q9Y6B6 1
Runx1 regulates transcription of genes involved in differentiation of hscs 0.5551841991983983 1.0529558385578148 0.2923612324554974 1.0 0.9565736177115352 42 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 29
Interleukin 2 family signaling 0.5871275627715612 1.0463876200498623 0.2953821061757269 1.0 0.9636462344270728 4 P40763 1
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.5458144913902345 1.0386465899168973 0.2989691294174008 1.0 0.9636462344270728 33 P63167,P08238,Q02790,O60884,Q13561,Q9Y6G9,P61163,P25685,P31948,Q13409,P52907,Q9UJW0,P11142,P47755,P04350,Q13451,P68371,P31689,Q9BUF5,P07900,Q15185,Q96FJ2,Q9BVA1,Q9NZ32,P47756,O43237 26
Pcna dependent long patch base excision repair 0.5169879695982529 1.038625344486205 0.2989790139202033 1.0 0.9636462344270728 19 P15927,P27695,Q15054,P12004,P39748,P18858 6
Circadian clock 0.4941962251116503 1.038495707141274 0.2990393328247154 1.0 0.9636462344270728 12 Q96EB6,P43490,Q86X55 3
G2 m dna replication checkpoint 0.5839887640449642 1.0325509466361082 0.3018140941034284 1.0 0.9636462344270728 4 Q99640,P06493,O95067 3
Mastl facilitates mitotic progression 0.5839887640449624 1.0325509466361007 0.3018140941034319 1.0 0.9636462344270728 4 P30153,P06493,P30154 3
Polo like kinase mediated events 0.4731703480029606 1.0313855202331836 0.3023600683153684 1.0 0.9636462344270728 7 Q99640,Q5TKA1,O95067,P30307 4
Mtor signalling 0.5026761400140692 1.027783797766338 0.3040515393564522 1.0 0.9636462344270728 15 P49815,Q96B36,Q13131,P06730,P62753 5
Erks are inactivated 0.4715579620625076 1.0225896598200532 0.306501900604601 1.0 0.9636462344270728 7 P51452,P27361,P30153,Q14738,P30154 5
Hedgehog off state 0.5463031747804986 1.0221236761558676 0.3067223686239915 1.0 0.9636462344270728 53 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,O75665,P25789,P25786,P28066,O00233,P17980,P04350,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,P63208,P68371,Q9BUF5,P55036,P62191,P17612 35
Influenza infection 0.2298190483813185 1.0187217223100289 0.3083350969413205 1.0 0.9636462344270728 131 P62244,P62241,P62899,P62280,P50914,P60866,P32969,P05386,P46776,P62917,P62906,P62861,P46781,P18621,P35268,O00505,O00410,P39019,P62851,P62424,O15514,P25398,P62269,P62249,P61254,P30050,P40429,P63220,Q02878,P61353,P05387,P37198,P46782,P46778,P83731,P62273,P62266,P61927,P46777,P19525,P84098,P62829,P63173,P62263,P55735,P61513,P08708,P62081,P05388,P62826,P62854,P62847,P42766,P15880,P08865,O00629,P62841,P62701,P62277,P26373,P62913,P18124,P62753,P62888,P61247,Q9Y3U8,P09874,P07900,P62857,P23396,O15504,O14980,P62750,P62487 74
Traf6 mediated irf7 activation in tlr7 8 or 9 signaling 0.9267265581134206 1.0114046918650017 0.3118227764806294 1.0 0.9636462344270728 2 Q13404 1
C type lectin receptors clrs 0.5317714899952727 1.01084510721647 0.3120905701184833 1.0 0.9636462344270728 62 P28070,Q8TBC4,P20618,O43242,P43686,O14818,Q13200,O00487,P62333,Q13404,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,Q14790,P17980,O95999,P28074,P62195,P49720,O43865,P61289,O00231,O75832,Q99436,P63208,P61081,O15111,P55036,P62191,P17612,P49427 39
Uptake and function of anthrax toxins 0.5525579372683643 1.0071785625059422 0.3138489729920564 1.0 0.9636462344270728 5 P52564 1
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.4767712156309792 1.006159935628941 0.3143386411630984 1.0 0.9636462344270728 9 P68036,Q93009,P45974,Q16763,P61086,P49427 6
Heme biosynthesis 0.5507778991541659 0.9990067304385508 0.3177914308982754 1.0 0.9636462344270728 5 P08397 1
Pcp ce pathway 0.5434081773985634 0.994593520458974 0.3199340001810662 1.0 0.9636462344270728 51 P28070,P09497,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P07737,P49720,P61289,O00231,O75832,Q99436,P05771,P61586,P55036,P62191 33
Transcriptional regulation by tp53 0.2347205367654711 0.9892152350436848 0.3225578459911498 1.0 0.9636462344270728 142 P24941,Q13131,Q96S44,Q92696,Q9UIV1,Q16881,P15927,P42771,Q13526,Q15370,Q86X55,P30044,P52564,Q9NQ88,Q99873,P06493,P30307,Q92597,P42575,Q9UQ84,Q15369,O96017,O75175 23
Switching of origins to a post replicative state 0.5243982284653809 0.9886524734284012 0.32283320333404 1.0 0.9636462344270728 64 P24941,P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9Y619,Q9UNM6,P28072,O43929,P60900,P20248,Q99741,Q15008,P35998,Q9UL46,Q13309,P25787,P25789,P25788,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,O00232,P63208,P55036,P62191,Q9UBD5 39
Gdp fucose biosynthesis 0.91802358225716 0.98135401152948 0.3264181963094521 1.0 0.9636462344270728 2 Q13630 1
Cargo trafficking to the periciliary membrane 0.5090308269602448 0.9799768999952968 0.3270975213852365 1.0 0.963648299516672 20 P50991,Q9H0F7,P48643,Q9NV70,Q8IYI6,P78371,P36405,P17987,P49368,P50990,P18085,Q8TAG9 12
Activation of the pre replicative complex 0.5152843930529399 0.9718340017780488 0.3311331373852992 1.0 0.968080778173878 23 P25205,P49643,P24941,P15927,O43929,Q99741,P49642,Q9NR33,P33991,P35244,Q9Y619,P27694,Q9UBD5 13
Sema3a pak dependent axon repulsion 0.5195113171242087 0.9700731310488634 0.3320100408607171 1.0 0.968080778173878 6 P08238,P23528,Q13177 3
Degradation of beta catenin by the destruction complex 0.5395041542690554 0.9673641338781702 0.3333620331207485 1.0 0.9693122096583444 50 P28070,P20618,Q99460,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,Q15008,P35998,Q9UL46,P30153,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P56545,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,O00232,P63208,Q04726,Q13363,P55036,Q14738,P62191 38
Transcriptional regulation by runx3 0.5404374070997647 0.9650189463007124 0.3345353221899736 1.0 0.9693122096583444 46 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P42771,P60900,Q13485,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 31
Trna modification in the nucleus and cytosol 0.5005188146915791 0.9648774940804384 0.334606175246614 1.0 0.9693122096583444 18 Q96FX7,Q9H974,Q9UI30,Q6YHU6,Q08J23,Q7Z4G4,Q9UJA5,Q9UET6,Q96S44,Q9NPF4,Q9UBP6 11
Phase ii conjugation of compounds 0.5278519238516932 0.954082246582318 0.3400420118730425 1.0 0.9735717615932136 31 Q9UI30,Q96IU4,P28161,P14550,Q9HBK9,O95861,P78417,Q8WUX2,P23526,O75223,Q9NZL9,P51580,O43708,P10768,P21266,P48507,Q96KP4 17
Copi independent golgi to er retrograde traffic 0.5245063603482325 0.9537993691337896 0.3401852088114396 1.0 0.9735717615932136 29 P47756,P63167,P61163,Q9UJW0,P47755,P04350,Q13561,Q15042,P68402,P68371,Q9BUF5,Q96FJ2,Q9Y6G9,O43237,Q9NZ32,P52907,Q13409,Q9H2M9 18
Other interleukin signaling 0.5640970902560613 0.945352772693114 0.344478804638725 1.0 0.975194621116412 4 P40222,P42574 2
Tbc rabgaps 0.502296544726167 0.9434737066975798 0.3454386580433488 1.0 0.975194621116412 20 P49815,Q9NZ52,Q9UJ41,Q9NVG8,Q15276,P62330,Q92930,Q9UJY5,Q9UJY4 9
Darpp 32 events 0.4673941305973224 0.9340946869897822 0.3502550523406245 1.0 0.9782372514445516 10 P62136,Q00535,Q08209,P30153,Q14738,P10644,P17612 7
Pp2a mediated dephosphorylation of key metabolic factors 0.67087896658242 0.9291415727097864 0.3528157221501735 1.0 0.9782372514445516 3 P30153,Q14738 2
Signaling by nodal 0.670317326593661 0.9269744645994626 0.3539397925557521 1.0 0.9782372514445516 3 P27361,Q13485 2
Signaling by activin 0.670317326593661 0.9269744645994626 0.3539397925557521 1.0 0.9782372514445516 3 P27361,Q13485 2
Signal attenuation 0.6703173265936496 0.92697446459942 0.3539397925557743 1.0 0.9782372514445516 3 P62993,P27361 2
Activation of the ap 1 family of transcription factors 0.6703173265936422 0.9269744645993908 0.3539397925557894 1.0 0.9782372514445516 3 P27361,Q16539 2
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.5317240710071238 0.9243388110312304 0.3553099418188552 1.0 0.9796895483160668 51 P28070,P20618,P06400,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,Q13309,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,Q99436,O75832,P55036,P62191 31
Signaling by hedgehog 0.5239309504247758 0.919215857767712 0.3579826782760458 1.0 0.983980581569805 58 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,O75665,P25789,P25786,P49407,P28066,O00233,P17980,P04350,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,P63208,P68371,Q9BUF5,P55036,P62191,P17612 36
Ikk complex recruitment mediated by rip1 0.5579707427118097 0.9187008120271214 0.3582520849799924 1.0 0.983980581569805 4 Q13404 1
Serine biosynthesis 0.6661050266779054 0.9107465561715182 0.3624289276580874 1.0 0.9866663316980302 3 P78330,Q9Y617 2
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.6656367675955188 0.908945418716935 0.3633789375785836 1.0 0.9866663316980302 3 Q92597 1
Sumo is transferred from e1 to e2 ube2i ubc9 0.6655105101469267 0.9084598742114656 0.3636353044086284 1.0 0.9866663316980302 3 Q9UBT2 1
Sumo is conjugated to e1 uba2 sae1 0.6655105101469267 0.9084598742114656 0.3636353044086284 1.0 0.9866663316980302 3 Q9UBT2 1
Cell extracellular matrix interactions 0.4544990737439267 0.907616110242852 0.3640810796767666 1.0 0.9866663316980302 8 Q13418,Q15404,P50552 3
Advanced glycosylation endproduct receptor signaling 0.4516799875878443 0.8924808972893241 0.3721352273103182 1.0 1.0 8 P09429,P27361,P47755,P17931,P28482 5
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4770560162354061 0.889499463107137 0.3737347116255867 1.0 1.0 15 Q9Y2Z0,Q13404,P52564,P42575 4
Uch proteinases 0.526315679775015 0.8890187823960588 0.3739929856158022 1.0 1.0 50 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,Q9Y4E8,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,Q9Y5K5,P55036,P62191 31
Lagging strand synthesis 0.4929242891238278 0.8784945777996709 0.3796753789515166 1.0 1.0 21 P49643,P15927,Q15054,P51530,P35250,P49642,P12004,P27694,P39748,P18858 10
Insulin processing 0.4585657992768355 0.8663596530382478 0.3862929625294669 1.0 1.0 11 Q9NV70,Q8TAG9 2
Asparagine n linked glycosylation 0.218144086906662 0.860493013631494 0.3895173330141124 1.0 1.0 126 Q96IJ6,Q8N6T3,O95394,O60547,Q9UP83,Q9Y5P6,Q9H553,P47755,Q9BUF5,P04350,Q9Y6B6,O15027,P33908,Q13409,Q13630,O43237,P18085,P53602 18
Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0.6503791069924169 0.8505955325547089 0.3949940719533651 1.0 1.0 3 P05771,P17931 2
Gamma carboxylation hypusine formation and arylsulfatase activation 0.4591214211876743 0.8496428336645825 0.3955236900730043 1.0 1.0 12 Q9BZG8,Q9BU89,Q9H2P9,Q9HA64,P63241,Q9BQC3,P49366 7
Aryl hydrocarbon receptor signalling 0.648211253602914 0.842362306967422 0.399585184750822 1.0 1.0 3 Q15185 1
Clec7a dectin 1 induces nfat activation 0.5395579262471791 0.8393350759090022 0.4012813053352433 1.0 1.0 4 O43865 1
Ephb mediated forward signaling 0.4764501619520901 0.8359809070140529 0.4031656442868421 1.0 1.0 18 P23528,P61586,P61160,O15145,O00401,Q92747 6
Regulation of tnfr1 signaling 0.4368434751472256 0.8353804168836628 0.4035035523189749 1.0 1.0 7 Q13107,O15111,Q14790,P63244 4
Cd28 dependent vav1 pathway 0.510385133333633 0.8160956645446426 0.4144454233683921 1.0 1.0 5 P62993,Q13177 2
Constitutive signaling by akt1 e17k in cancer 0.4328726845704645 0.8143200098201502 0.4154616495135153 1.0 1.0 7 P49815,Q96B36,P49840 3
Trna processing in the mitochondrion 0.5324808959848215 0.8091749453417051 0.4184145242681711 1.0 1.0 4 Q9BQ52 1
Deadenylation of mrna 0.4676808675431125 0.805832816365177 0.4203392534030228 1.0 1.0 17 P60842,Q9UIV1,P06730,Q9H9A5,Q9H074,O75175,Q5TAX3 7
Dna repair 0.2184770953966882 0.8037455157905042 0.4215439616543759 1.0 1.0 132 Q9H9Q2,Q8N2W9,P24941,P29372,P16455,Q15054,Q16658,O00213,Q6P6C2,P15927,P27695,P20248,Q14258,Q9UBW8,Q9NXR7,Q92905,Q9NY27,Q7L5N1,Q86W56,P12004,P18858,Q8N9N2,Q9NR33,P13010,P18887,P51530,P54727,Q04323,P53041,P49917,Q9C0B1,O95551,P20585,Q15004,P60510,Q13098,Q9UQ84,Q96B01,Q9NZJ0,P35250,O96017,Q9UNS2,P43246,P27694,P39748,P62487 46
Phenylalanine metabolism 0.8635597978663688 0.7973041339837728 0.4252744200193894 1.0 1.0 2 P61457 1
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.47915477007208 0.7784664134498666 0.4362940993977489 1.0 1.0 23 P15927,P27695,Q9NR33,Q15054,P35250,Q86W56,P12004,P27694,P39748,P18858 10
Negative feedback regulation of mapk pathway 0.6310025273799358 0.7775853480637267 0.4368135014966861 1.0 1.0 3 P28482,P27361 2
Defects in biotin btn metabolism 0.4255926632147018 0.7759578650003094 0.4377738646587579 1.0 1.0 7 P50747,P05165,Q13085 3
Translesion synthesis by polk 0.4375272863253414 0.7754284640406609 0.438086521052031 1.0 1.0 10 P15927,P40937,P35250,P35244,P35249,P12004,P27694 7
Map2k and mapk activation 0.4517178272432781 0.7735649037811414 0.4391881333244543 1.0 1.0 14 Q02750,P30086,P27361,P31946,P41240,P10398,P28482,P49407 8
Gap filling dna repair synthesis and ligation in gg ner 0.4662360985537714 0.7669745621976454 0.4430966399403979 1.0 1.0 19 P15927,Q9NR33,Q15054,P18887,P35250,P12004,P27694,P18858 8
Dna damage recognition in gg ner 0.4626629789866202 0.7637102307749215 0.4450399426287297 1.0 1.0 18 Q9H9Q2,Q13098,Q9UBW8,Q92905,Q7L5N1,P54727 6
Nade modulates death signalling 0.6270710474585917 0.7629440885703573 0.4454967410758934 1.0 1.0 3 P62258,P42575 2
Ticam1 rip1 mediated ikk complex recruitment 0.6268673129539446 0.762187082756887 0.4459483544443063 1.0 1.0 3 Q13404 1
Signaling by ntrk2 trkb 0.422661567165458 0.7606114978610159 0.4468891501466268 1.0 1.0 7 Q06124,Q00535 2
Antigen processing cross presentation 0.5030548783601111 0.7599102494040142 0.4473082346579282 1.0 1.0 52 P09429,P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,O15111,P55036,P62191 31
Metabolism of nucleotides 0.5045282953902841 0.7595471582794954 0.4475253152394018 1.0 1.0 46 Q9NRF8,P11172,P33316,P00390,Q9Y3Z3,Q96DE0,Q9H773,Q16881,P30520,Q9UKK9,P31939,P12268,P15531,P04818,P23921,P35754,P30085,P04183,P07741,P00492,Q01433,P22392,P20839,P17812,P49915,P30566,P00491,P31350,P22234,P22102,Q06203,P00568,Q9BY32,P32321,O43598,Q9P2T1,P55263 37
Mapk6 mapk4 signaling 0.5006705867358057 0.7462964729724447 0.4554883415784152 1.0 1.0 52 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P06493,P62195,P49720,P61289,O00231,O75832,Q99436,P55036,P62191,P17612 31
Termination of translesion dna synthesis 0.4649330725680281 0.7455016943817777 0.4559684872247418 1.0 1.0 20 Q15004,P15927,Q14258,Q9NR33,Q15054,P35250,P12004,P27694 8
Signaling by leptin 0.8458731049971944 0.7394384663166229 0.4596407917173875 1.0 1.0 2 Q06124 1
G2 phase 0.8444693992139267 0.7348946862097161 0.4624036348285885 1.0 1.0 2 P24941 1
Metabolism of porphyrins 0.4248093262449202 0.7296177635914268 0.4656238610434018 1.0 1.0 9 P30043,P08397,P53004 3
Rho gtpases activate wasps and waves 0.4615000291829117 0.7278111180035673 0.4667292177286251 1.0 1.0 20 P27361,P59998,Q9UQB8,Q9Y6W5,P61160,O15145,O00401,Q92747 8
Enos activation 0.4900923322772951 0.7267787383879266 0.4673615097794621 1.0 1.0 5 O94760,O75608 2
Activation of bh3 only proteins 0.4300428691834078 0.7170285788860687 0.473356462778616 1.0 1.0 11 P63167,P63104,Q04917,Q9Y3B8,P31751,P31946,P62258,Q96FJ2,P27348 9
Activation of gene expression by srebf srebp 0.4525088922229932 0.7114178314363332 0.4768253524290622 1.0 1.0 18 Q13907,Q13085,Q86X55,Q03426,P48449,P14324,P53602,O00763 8
Translesion synthesis by polh 0.4352764653242229 0.70668509721293 0.4797621927691098 1.0 1.0 13 P15927,P40937,Q8TAT6,P35250,P35244,P35249,P12004,P27694 8
Signal regulatory protein family interactions 0.6090985678180303 0.6968699587694159 0.4858841796264437 1.0 1.0 3 P62993,Q06124 2
Cytosolic sulfonation of small molecules 0.5051724355626166 0.695073405669704 0.487009300160425 1.0 1.0 4 O95861,Q96IU4 2
Synthesis of substrates in n glycan biosythesis 0.4547839168598678 0.6935069861087023 0.4879914431574614 1.0 1.0 20 O95394,Q96IJ6,Q9Y5P6,O60547,Q13630,P53602 6
Dna strand elongation 0.4773920736749431 0.6927447204390303 0.4884697689397881 1.0 1.0 30 P49643,Q9BRT9,P15927,P27694,Q15054,P33991,P51530,Q9Y248,P35250,P49642,P12004,Q9BRX5,P39748,P18858 14
Synthesis of leukotrienes lt and eoxins ex 0.8304323413812543 0.6898861554759111 0.490265782805142 1.0 1.0 2 Q14914 1
Biosynthesis of specialized proresolving mediators spms 0.8304323413812543 0.6898861554759111 0.490265782805142 1.0 1.0 2 Q14914 1
Activation of atr in response to replication stress 0.4632141083400357 0.6837798165378502 0.4941142134984841 1.0 1.0 24 P25205,P24941,P15927,O43929,Q99741,P33991,P35250,P35244,Q9Y619,P27694,Q9UBD5,P30307 12
Oncogene induced senescence 0.4192405646928135 0.6811909504098884 0.4957506734461385 1.0 1.0 10 P42771,P27361,Q00534 3
Insulin receptor signalling cascade 0.4067632649185306 0.678516509574681 0.4974442595994508 1.0 1.0 7 P62993,P27361,Q06124,P28482 4
Programmed cell death 0.3013924266886945 0.6768997664927849 0.498469552276692 1.0 1.0 108 P63167,P09429,Q96GX9,P28070,P31946,Q99460,P26583,P20618,O43242,P43686,O14818,Q13200,O00487,P62333,P28482,Q9UNM6,P40763,P28072,P42771,P60900,P35998,Q15008,Q9UL46,P25787,P25788,P25789,Q16543,P25786,P28066,O00429,Q04917,O00233,Q14790,P27361,P17980,P28074,P55212,P62195,P49720,P61289,O00231,O75832,O00232,O00560,Q99436,Q16625,Q16611,P62258,Q9UNE7,Q9UKG1,P55036,O00273,Q96FJ2,P62191,Q9UJU6,Q13464 56
Butyrate response factor 1 brf1 binds and destabilizes mrna 0.4292900072753812 0.6762852356428283 0.498859564883467 1.0 1.0 13 Q96B26,Q8IZH2 2
Regulation of runx1 expression and activity 0.4056656136267776 0.6729274996818043 0.5009934161244898 1.0 1.0 7 Q00534,Q06124,P29590,P12931,Q13951 5
Nephrin family interactions 0.4169458348719049 0.6695672272027147 0.5031337117089028 1.0 1.0 10 O43639 1
Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.6003853517739431 0.6653977835429502 0.5057961022269994 1.0 1.0 3 P24941 1
Resolution of abasic sites ap sites 0.4677905925308869 0.6628466129093608 0.5074287966568316 1.0 1.0 28 P29372,P15927,P27695,Q9NR33,Q15054,P18887,P35250,Q86W56,P12004,P27694,P39748,P18858 12
Intrinsic pathway for apoptosis 0.4565645255799806 0.6625018613012499 0.5076496423537233 1.0 1.0 23 P63167,Q04917,Q14790,Q96GX9,P40763,P31751,Q9Y3B8,P42771,P31946,P27361,Q16611,P62258,P42574,Q96FJ2,P28482,P27348,P55210 17
Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.4265407541816504 0.6451127235711702 0.5188541390549699 1.0 1.0 14 Q96B26,Q8IZH2 2
Rho gtpases activate paks 0.419170350032819 0.6433805427432471 0.5199772055891945 1.0 1.0 12 P60953,P35240,Q7Z406,Q14247,P60660,Q13177 6
Processive synthesis on the c strand of the telomere 0.4192953610874541 0.6263076542646631 0.5311131667800426 1.0 1.0 13 P15927,Q15054,P51530,P12004,P39748,P18858 6
Regulation of tp53 expression and degradation 0.4257771027238698 0.6246714458335736 0.5321867175421553 1.0 1.0 15 P42771,P06493,P24941,O96017 4
Transcriptional regulation of pluripotent stem cells 0.8082537900056177 0.6205190958731864 0.5349160858715922 1.0 1.0 2 P40763 1
Maturation of sars cov 1 nucleoprotein 0.5869471268742629 0.6176743567072588 0.5367900188944168 1.0 1.0 3 P49840 1
Regulation of cholesterol biosynthesis by srebp srebf 0.4543700885923899 0.6166347011803643 0.5374757005604238 1.0 1.0 26 Q13907,Q15436,Q13085,Q9Y6B6,Q86X55,Q03426,P48449,P14324,P62826,P53602,O00763 11
Regulation of mrna stability by proteins that bind au rich elements 0.4592330977701664 0.6152934252465626 0.5383609587716547 1.0 1.0 67 P39687,P28070,P31946,P20618,P43686,Q16539,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,Q8IZH2,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,Q9Y2L1,P17980,P28074,Q01105,P62195,P49720,P61289,O00231,O75832,Q99436,O00232,Q96B26,P55036,P62191,Q92945 38
Diseases of mismatch repair mmr 0.5860713282785791 0.6146009206316355 0.5388183062847149 1.0 1.0 3 P20585,P43246 2
Intra golgi traffic 0.4165193368922117 0.6126135135157661 0.5401319207460953 1.0 1.0 13 P33908 1
Cellular response to chemical stress 0.4366483345980111 0.6084007279937349 0.5429217287686301 1.0 1.0 76 P28070,P20618,P43686,P00390,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P30043,Q16881,Q9BX63,P40763,P28072,P60900,Q15008,P35998,P19784,Q9UL46,Q86X55,P30044,Q13309,P25787,P25789,P25788,P25786,P28066,O00233,Q14145,P17980,P28074,P62195,P49720,P30041,P61289,O00231,O75832,Q99436,O00232,P63208,P32119,P55036,P53004,P62191 45
Mitotic metaphase and anaphase 0.2185318348432126 0.601523666434968 0.547491253626331 1.0 1.0 154 P28070,P20618,Q13200,P62333,Q96EA4,P60900,O43684,Q13409,P25787,P25788,P25789,P25786,Q8N0S6,P28066,Q9UN37,O00233,Q9P258,P04350,P28074,P06493,P62195,P49720,P61289,P62826,Q99986,O75832,Q99436,Q9H900,Q15691,Q9HBM1,Q9BUF5,O43237 32
P75ntr regulates axonogenesis 0.5808866645365351 0.5965040310346855 0.5508385617590545 1.0 1.0 3 P61586 1
Cytokine signaling in immune system 0.2398870918335769 0.5947106201799323 0.5520369216086203 1.0 1.0 196 P09429,P28070,P60842,Q8TBC4,P51617,P29372,P20618,Q06124,O43242,Q16658,O14818,O14733,Q13200,O00505,O00487,P62333,O15344,P46109,Q13325,Q9UNM6,Q13404,P51452,P14174,P40763,P28072,P23528,P60900,P35998,P78417,Q15370,P26038,Q13526,P52564,P25787,P25788,P25789,Q00169,P25786,P28066,P40222,O00170,O00233,Q99439,P27361,Q13126,P28074,P62195,P55735,P49720,P61289,P63208,P05388,O75832,Q99436,O00629,P61221,P61081,Q15369,P55036,P62191,P17612 61
Activation of nima kinases nek9 nek6 nek7 0.4588670978085102 0.5944363481108572 0.5522203034232198 1.0 1.0 5 P06493,Q8TD19,O95067 3
Mtorc1 mediated signalling 0.4015203055510069 0.592813657814353 0.5533058663760082 1.0 1.0 10 P62753,P06730,Q96B36 3
Activation of ppargc1a pgc 1alpha by phosphorylation 0.5779096077662537 0.5861901819513056 0.5577477187237301 1.0 1.0 3 Q16539 1
Runx2 regulates osteoblast differentiation 0.4350413326997753 0.582140222181536 0.5604722343300768 1.0 1.0 6 P28482,P27361,P06400,Q13951 4
Cytochrome c mediated apoptotic response 0.4348266711194438 0.581217239550344 0.5610940501674144 1.0 1.0 6 P55210,P27361,P28482,Q96GX9 4
Signaling by fgfr1 0.394742551156197 0.5785257106097333 0.5629092442503656 1.0 1.0 9 P62993,P30153,P27361,Q06124 4
Signaling by fgfr3 0.394742551156197 0.5785257106097333 0.5629092442503656 1.0 1.0 9 P62993,P30153,P27361,Q06124 4
Signaling by fgfr4 0.394742551156197 0.5785257106097333 0.5629092442503656 1.0 1.0 9 P62993,P30153,P27361,Q06124 4
Receptor mediated mitophagy 0.4546421916488253 0.5771185961685423 0.5638593428447356 1.0 1.0 5 P67870,Q9H1Y0,P19784 3
Netrin 1 signaling 0.4082824831311262 0.572504586892826 0.5669801792378426 1.0 1.0 13 O00401,Q00169 2
Ret signaling 0.3851631727750623 0.5707814437356029 0.5681478030287634 1.0 1.0 7 P17612 1
Early phase of hiv life cycle 0.3924172441515608 0.5672448542296719 0.570547837642033 1.0 1.0 9 P39748,P18858 2
Tnf signaling 0.3951321006000847 0.5618115355127857 0.5742444317964128 1.0 1.0 10 Q14790,O95429,Q13107,O15111,Q15750,P63244 6
Deadenylation dependent mrna decay 0.4662454555452878 0.5596483176027158 0.575719340916919 1.0 1.0 44 Q9Y333,Q969T7,Q96B26,O75175,Q9Y2L1,P60842,Q96C86,P26196,Q8IZH2,Q96F86,Q86TB9,Q9H9A5,Q9Y450,Q9H074,Q9UIV1,Q5TAX3 16
Recognition of dna damage by pcna containing replication complex 0.4234098237049317 0.5531344108651046 0.5801713752318458 1.0 1.0 19 P15927,Q9NR33,Q15054,Q9NZJ0,P28340,P35250,P12004,P27694 8
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.4340731711297458 0.5524778717781285 0.5806209910813158 1.0 1.0 23 Q15004,P15927,Q14258,Q9NR33,Q15054,P35250,P12004,P27694 8
Glucuronidation 0.5666947486661027 0.5478725079738279 0.5837794471740507 1.0 1.0 3 O60701,Q16851 2
Met receptor recycling 0.4269513986120791 0.547669379275854 0.583918941217511 1.0 1.0 6 P46109,Q9NZ52,P62330 3
Dna damage bypass 0.4396690872656904 0.5455132816822243 0.5854005483342808 1.0 1.0 26 Q15004,P15927,Q14258,Q9NR33,Q15054,Q8TAT6,Q9NZJ0,P28340,Q16531,P35250,P12004,P27694 12
Signaling by hippo 0.4254191141668192 0.5412154459348686 0.5883590923787132 1.0 1.0 6 P31946,P62258,P42574,Q4VCS5 4
Sema4d in semaphorin signaling 0.3907366764453335 0.5407775912324484 0.5886608901467654 1.0 1.0 10 P60660,Q7Z406 2
Interleukin 3 interleukin 5 and gm csf signaling 0.389208575896106 0.5335245801390152 0.5936705005553728 1.0 1.0 10 P46109,P17612 2
Runx1 regulates expression of components of tight junctions 0.5578052308921648 0.5181397158951492 0.6043607918388822 1.0 1.0 3 Q16625 1
Sealing of the nuclear envelope ne by escrt iii 0.3863346117690919 0.50260853860336 0.6152395248304514 1.0 1.0 11 Q9UN37,Q9BUF5 2
Formation of incision complex in gg ner 0.4002340556915431 0.5025885111128777 0.6152536084426021 1.0 1.0 15 Q92889,P15927,Q86WJ1,P18074,P09874,P32780,Q16531,P54727,P35244,P27694,Q9UGN5 11
Gap junction trafficking and regulation 0.3928156274716226 0.4995440817122243 0.6173961400759689 1.0 1.0 13 P09497,Q9BUF5,P04350 3
Hdr through mmej alt nhej 0.3733100708627288 0.4952439011604992 0.6204279648888695 1.0 1.0 8 P39748 1
Vitamin b5 pantothenate metabolism 0.4139210849328336 0.4936072440347764 0.621583583810384 1.0 1.0 6 Q96CD2 1
Rho gtpase effectors 0.201002198894681 0.4921037907481494 0.6226459726010716 1.0 1.0 136 P63167,P35080,P31946,P60660,Q8NBT2,Q96EA4,Q92747,P35240,P23528,Q13526,O43684,Q13409,Q8N0S6,Q04917,Q9P258,P27361,P04350,P59998,Q9UQB8,Q07866,P07737,P55735,P30307,P68371,P62993,Q9H900,Q7Z406,P05771,Q15691,Q9HBM1,Q9HD26,Q9BUF5,P61586,Q9Y6W5,P61160,Q9Y266,O15145,O00401,O43237 39
Synthesis of ip3 and ip4 in the cytosol 0.4525280898876508 0.4895960871006377 0.624419745873912 1.0 1.0 4 O15357,P19174,Q01968 3
Mrna decay by 3 to 5 exoribonuclease 0.4002925494109906 0.4880519764802763 0.6255130257066603 1.0 1.0 16 Q969T7,Q96B26,Q9Y2L1 3
Cytoprotection by hmox1 0.4360701111438523 0.4848537969923769 0.6277800585395759 1.0 1.0 67 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P30043,Q9BX63,P40763,P28072,P60900,Q15008,P35998,P19784,Q9UL46,Q86X55,Q13309,P25787,P25789,P25788,P25786,P28066,O00233,Q14145,P17980,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,O00232,P63208,P55036,P53004,P62191 40
Hsf1 activation 0.3923069393629873 0.4815502753364321 0.6301254568973405 1.0 1.0 14 P15927,P08238,P27694,Q02790,P62258,P07900,P25685,Q15185,P35244,Q92598 10
Pi 3k cascade fgfr3 0.7577203818079787 0.4722102571896185 0.6367767190903568 1.0 1.0 2 Q06124 1
Stat5 activation 0.7577203818079787 0.4722102571896185 0.6367767190903568 1.0 1.0 2 Q06124 1
Stat5 activation downstream of flt3 itd mutants 0.7577203818079787 0.4722102571896185 0.6367767190903568 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr1 0.7577203818079787 0.4722102571896185 0.6367767190903568 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr2 0.7577203818079787 0.4722102571896185 0.6367767190903568 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr4 0.7577203818079787 0.4722102571896185 0.6367767190903568 1.0 1.0 2 Q06124 1
Interleukin 15 signaling 0.7577203818079783 0.4722102571896158 0.6367767190903588 1.0 1.0 2 P40763 1
Intraflagellar transport 0.38671535214308 0.471712760037774 0.6371318280383613 1.0 1.0 13 Q96EX3,Q9BUF5,P04350 3
Ptk6 regulates cell cycle 0.7560359348680576 0.4675376009256323 0.640115296820472 1.0 1.0 2 P24941 1
Signaling by wnt 0.3369272525210944 0.4651927284565005 0.6417934455698056 1.0 1.0 97 P28070,P09497,P20618,O43242,P43686,O14818,Q13200,O00487,P62333,Q9UNM6,P28072,Q96QK1,P60900,P35998,Q15008,Q70CQ2,P19784,P30153,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P09471,O60493,P17980,Q08209,P56545,P28074,P62195,P07737,P49720,P61289,P63208,O75832,O00231,O00232,Q99436,Q04726,Q9UBQ0,P05771,Q13363,P61586,P55036,P62191 47
Signaling by notch 0.4406579976781212 0.4634604883299323 0.6430343300196768 1.0 1.0 61 P28070,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,Q9Y6A5,P60900,P35998,Q9UL46,P25787,P25788,P25789,P67809,P25786,P49407,P28066,O00233,P17980,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,P63208,Q04726,P55036,P62191 34
Dual incision in gg ner 0.4177981717512528 0.4556139050860603 0.6486676422526845 1.0 1.0 25 Q92889,Q86WJ1,P15927,P40937,Q9NR33,Q15054,P18074,P28340,P32780,P09874,Q16531,P35244,P35250,P35249,P12004,P27694,Q9UGN5,P19447 18
Caspase activation via extrinsic apoptotic signalling pathway 0.4007537115899029 0.4410287947779955 0.6591921511229726 1.0 1.0 6 Q13546,Q9UKG1,Q14790,P42574 4
Pd 1 signaling 0.7453677709152224 0.4383990090862529 0.6610970646482186 1.0 1.0 2 Q06124 1
Negative regulation of the pi3k akt network 0.3920727470722815 0.4374363739661762 0.6617949097107536 1.0 1.0 17 P62993,P51617,P27361,Q06124,P30153,Q14738,P30154,P48426,Q8TBX8 9
Neutrophil degranulation 0.2178670949967134 0.4318361672362291 0.6658604911030668 1.0 1.0 176 P63167,P04075,P09429,P50990,P07437,P20618,Q99460,Q16539,O43242,P14618,Q13200,O95352,Q969Q5,O00487,Q9Y6G9,P28482,Q9UNM6,P18669,P11216,P53618,Q9NQR4,Q13442,P14174,P04080,Q9Y315,P35237,Q15008,P07858,P35998,P13798,P12268,P13473,P25787,P31949,P17858,P28066,Q99439,P30740,Q01518,P07741,P78371,P17931,P17980,P68402,P67870,P09972,P17900,P13639,P13010,P07384,P50395,P53396,P22392,P20839,P30041,P09960,P68371,O00231,P00491,O00232,Q8IUR7,O00560,Q99436,Q9UJU6,Q86VP6,O75874,Q9BXS5,P61586,P36871,P37108,P61160,Q9UQ80,O00754,Q13464,Q9NZ32,P46976 76
Metalloprotease dubs 0.3591458626508313 0.4310595725878612 0.6664250549726614 1.0 1.0 8 O95630,Q9NXR7 2
Flt3 signaling 0.3933554956041146 0.4124914389049934 0.6799792543612571 1.0 1.0 6 P62993,Q06124 2
Polymerase switching 0.3795934059688394 0.4109100433833532 0.6811384977131545 1.0 1.0 15 P49643,Q15054,P35250,P49642,P12004 5
Apoptosis 0.3319444288501459 0.3989040967376522 0.6899638704575084 1.0 1.0 96 P63167,P09429,Q96GX9,P28070,P31946,Q99460,P26583,P20618,O43242,P43686,O14818,Q13200,O00487,P62333,P28482,Q9UNM6,P40763,P28072,P42771,P60900,P35998,Q15008,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00429,Q04917,O00233,Q14790,P27361,P17980,P28074,P55212,P62195,P49720,P61289,O00231,O75832,O00232,Q99436,Q16625,Q16611,P62258,Q9UKG1,P55036,O00273,Q96FJ2,P62191,Q9UJU6,Q13464 53
Chrebp activates metabolic gene expression 0.4081114220536518 0.3986970871860467 0.6901164143882503 1.0 1.0 5 Q13085,O00763 2
Signaling by wnt in cancer 0.350950143866963 0.3954613900045429 0.6925024105996476 1.0 1.0 8 P30153,Q13363,Q14738,P56545 4
Signaling by mras complex mutants 0.4030186376895113 0.3807843556885779 0.7033632686583362 1.0 1.0 5 P31946,P36873,P10398 3
Downstream signaling of activated fgfr2 0.4196835406409881 0.3753286499470983 0.7074160614061118 1.0 1.0 4 Q06124 1
Downstream signaling of activated fgfr3 0.4196835406409881 0.3753286499470983 0.7074160614061118 1.0 1.0 4 Q06124 1
Downstream signaling of activated fgfr4 0.4196835406409881 0.3753286499470983 0.7074160614061118 1.0 1.0 4 Q06124 1
Downstream signaling of activated fgfr1 0.4196835406409881 0.3753286499470983 0.7074160614061118 1.0 1.0 4 Q06124 1
Activation of nmda receptors and postsynaptic events 0.4067132975987614 0.3723008686651026 0.7096688519348289 1.0 1.0 29 Q92796,Q13131,Q9BUF5 3
Innate immune system 0.2700531071947694 0.3716307026927805 0.7101678263189286 1.0 1.0 312 Q16539,Q9Y6G9,P18669,P53618,Q9NQR4,P14174,P23528,P35237,P35998,Q15008,P07858,P30153,P52564,P13473,P28066,O00233,P47755,O95999,Q08209,P68402,P67870,Q9UQB8,P50395,P53396,P22392,P30041,P20839,P09960,O75832,P00491,Q9H1Y0,P42575,Q86VP6,P61586,P61081,P55036,Q14738,P61160,O15145,Q13464,P17612,P46976,P49427,Q9H2U1,Q8TBC4,Q99460,O95352,P30154,P28482,P21283,Q13404,Q9UNM6,P11216,P13798,P12268,P25787,P25788,P25789,P31949,Q99439,Q01518,P78371,P59998,P49720,Q9Y2Z0,P81605,O00754,O00401,P63167,P51617,P07437,O43242,P14618,O14818,O14733,O00487,P61086,P51452,P35240,P04080,P28072,P60900,Q13526,Q3LXA3,Q32MZ4,P09972,P17900,P28074,P61289,P63208,P68371,P62993,O75874,O15111,P36871,P04075,P09429,P28070,P20618,Q06124,P43686,Q13200,Q969Q5,P62333,Q99538,Q92747,Q9Y315,Q14258,Q9UL46,Q9NVU0,P25786,P17858,Q14790,P30740,Q15366,P27361,P07741,P17980,P17931,Q13442,P13010,P07384,P13639,P62195,O43865,Q8IUR7,Q99436,O00231,O00232,O00560,Q9BXS5,Q9Y6W5,P37108,P62191,Q9UQ80,Q9UJU6,P50990,Q9NZ32 138
Tnfr1 induced nfkappab signaling pathway 0.3439980892094524 0.3662372284618587 0.714188064748893 1.0 1.0 8 Q13107,Q15750,O15111,P63244 4
Signaling by moderate kinase activity braf mutants 0.3718724811978715 0.3654804868653222 0.7147527701143073 1.0 1.0 16 Q02750,P30086,P27361,P31946,P41240,P10398,P28482,P49407 8
Dcc mediated attractive signaling 0.3806591988801286 0.3653687010411243 0.7148362016060203 1.0 1.0 6 O00401,P16333,P60953 3
Ovarian tumor domain proteases 0.3540685412903633 0.3616156327109718 0.7176392809738821 1.0 1.0 11 Q96FW1 1
Formation of apoptosome 0.4153810600884687 0.3613625471937899 0.7178284420502761 1.0 1.0 4 P27361,Q96GX9 2
Beta catenin independent wnt signaling 0.410348361983903 0.3381817634581724 0.7352262177551623 1.0 1.0 64 P28070,P09497,P20618,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,P35998,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P28074,P62195,P07737,P49720,P61289,O00231,O75832,Q99436,P05771,P61586,P55036,P62191 33
Assembly of the hiv virion 0.7035373385738426 0.3324156473353045 0.7395754248224387 1.0 1.0 2 Q99816 1
Golgi cisternae pericentriolar stack reorganization 0.3427850556658665 0.3309605371183669 0.7406742941001871 1.0 1.0 10 P27361,P06493,O95067,P28482,P62820 5
Pten regulation 0.3977932917073462 0.3235042905083687 0.746313358723419 1.0 1.0 70 P28070,P20618,Q99460,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,Q15008,P35998,P19784,Q9UL46,P29590,P25787,P25788,P25789,P25786,P28066,O00233,P27361,P17980,P67870,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,Q92995,O00232,Q9UNE7,P55036,P62191 38
Retrograde transport at the trans golgi network 0.3578374412840396 0.3226695069812816 0.7469455477812323 1.0 1.0 15 Q9UP83 1
Biotin transport and metabolism 0.334636514562631 0.3136477022933256 0.7537886251676944 1.0 1.0 9 P50747,P05165,Q13085,O00763 4
Degradation of the extracellular matrix 0.3343514478581177 0.3125513181574439 0.7546215686950453 1.0 1.0 9 Q9Y6W3 1
Tcf dependent signaling in response to wnt 0.4014919079682816 0.3061792344480652 0.7594681821744997 1.0 1.0 65 P28070,P20618,Q99460,P43686,O43242,O14818,Q13200,P62333,O00487,Q9UNM6,P28072,P60900,Q15008,P35998,P19784,Q9UL46,Q70CQ2,P30153,P25787,P25788,P25789,P25786,P28066,O00233,P17980,P67870,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,O00232,Q04726,Q13363,P55036,Q14738,P62191 39
Telomere c strand lagging strand synthesis 0.3785428535943331 0.3054737914074247 0.760005328063877 1.0 1.0 24 P49643,P15927,Q15054,P51530,P35250,P49642,P12004,P27694,P39748,P18858 10
Wnt mediated activation of dvl 0.6900617630544721 0.3013515623357823 0.7631464261009315 1.0 1.0 2 P19784 1
Biological oxidations 0.405457930072996 0.2881588105402506 0.7732251765121458 1.0 1.0 47 P11766,Q96IU4,P14550,Q8WUX2,O75223,O43708,O43488,Q96DG6,P28161,P78417,P23526,O00170,Q9UI30,Q9HBK9,P21266,O95861,Q9NZL9,Q15185,P10768,P48507,Q96KP4 21
Global genome nucleotide excision repair gg ner 0.4039655618972258 0.2879810334518538 0.7733612570579906 1.0 1.0 44 Q9H9Q2,Q86WJ1,Q9BT78,Q15054,P15927,Q9UBW8,Q92905,P28340,Q7L5N1,P12004,P18858,Q9NR33,P18887,P54727,Q92889,Q13098,Q16531,P35250,Q9UNS2,P27694 20
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.3908188927966546 0.286708291644085 0.7743356882071859 1.0 1.0 4 P40763 1
Heme signaling 0.3196478915486911 0.2857609723673001 0.7750612016945624 1.0 1.0 7 Q96EB6 1
Interleukin 17 signaling 0.3679550346773066 0.2851710821774649 0.7755130739902865 1.0 1.0 22 P51452,P51617,Q13616,P27361,Q16539,P30153,O14733,O15111,Q14738,P30154,P52564,P28482,Q15750,Q13404,P63208 15
Rho gtpases activate nadph oxidases 0.3258208812632023 0.2805805419530751 0.7790321420195427 1.0 1.0 9 Q13526,P27361,P05771,Q16539 4
Prolonged erk activation events 0.3546613842692576 0.2770708615039705 0.781725695400109 1.0 1.0 6 P28482,P46109,P27361,P31946 4
Suppression of phagosomal maturation 0.3544125913434611 0.2762837535743851 0.7823301332405985 1.0 1.0 6 P52294,Q9H267,Q14974,Q9UI12,P20339 5
Rab regulation of trafficking 0.3944478085205377 0.2656961431588444 0.7904732339690801 1.0 1.0 40 P49815,Q9NZ52,Q9Y2L5,Q9UL25,Q9UJ41,P62258,P31150,P62820,Q9NVG8,Q15276,Q9H2M9,P62330,Q8TC07,Q92930,Q9UJY5,Q9UJY4,A5PLN9 17
Lipophagy 0.3825842696629145 0.2637457573338679 0.7919758342398879 1.0 1.0 4 P54619,P54646,P11142 3
Signaling by mapk mutants 0.6701291409320723 0.2583998987358097 0.7960982947418243 1.0 1.0 2 Q99956 1
Mapk1 erk2 activation 0.6701291409320707 0.2583998987358065 0.7960982947418267 1.0 1.0 2 Q06124 1
Golgi associated vesicle biogenesis 0.3798168989696309 0.2583699275226229 0.796121423218763 1.0 1.0 31 Q9Y6B7,Q8NC96,P49407,Q14671 4
Toll like receptor tlr1 tlr2 cascade 0.3650007003806448 0.2577107442174549 0.7966301534484137 1.0 1.0 24 P51452,P09429,P51617,Q13616,P27361,Q16539,P30153,O14733,O15111,Q14738,P30154,P52564,P28482,Q15750,Q13404,P63208 16
Myd88 independent tlr4 cascade 0.3726027271607522 0.253450625121333 0.7999200111567539 1.0 1.0 28 P51452,P09429,Q14790,P51617,Q13616,P27361,Q06124,Q16539,P30153,O14733,O15111,Q14738,P30154,P52564,P28482,Q15750,Q13404,P63208 18
Assembly of collagen fibrils and other multimeric structures 0.4640390192234901 0.2495529987679603 0.8029330501876109 1.0 1.0 3 Q03001 1
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.345421068143197 0.248623258971161 0.8036522152648653 1.0 1.0 6 Q06124 1
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.3592030820447758 0.2432392135481459 0.8078200908544881 1.0 1.0 5 P30153,P17612,Q14738 3
G0 and early g1 0.3184922500546785 0.2420429703230263 0.8087468674329299 1.0 1.0 10 P06493,P24941,P12004 3
Dscam interactions 0.4568941308621012 0.23318479939987 0.8156179088550346 1.0 1.0 3 P63000,Q16539 2
Irs mediated signalling 0.3548969235162287 0.2314877403803632 0.8169359085795429 1.0 1.0 5 Q06124 1
Growth hormone receptor signaling 0.3365077817706164 0.2227564413982045 0.8237250709154265 1.0 1.0 6 P27361 1
Epha mediated growth cone collapse 0.3112277671652422 0.2181818129672077 0.8272874548949445 1.0 1.0 10 P60660,Q7Z406 2
Negative regulators of ddx58 ifih1 signaling 0.3176833965775177 0.2167103756332497 0.8284340615672947 1.0 1.0 12 Q15366,Q9H1Y0,P61086,Q13526 4
Activated ntrk2 signals through frs2 and frs3 0.4493900455708288 0.2167096677359622 0.8284346132792222 1.0 1.0 3 Q06124 1
Tie2 signaling 0.4493900455708288 0.2167096677359622 0.8284346132792222 1.0 1.0 3 Q06124 1
Signaling by flt3 itd and tkd mutants 0.4493900455708288 0.2167096677359622 0.8284346132792222 1.0 1.0 3 Q06124 1
Frs mediated fgfr2 signaling 0.4493900455708288 0.2167096677359622 0.8284346132792222 1.0 1.0 3 Q06124 1
Frs mediated fgfr4 signaling 0.4493900455708288 0.2167096677359622 0.8284346132792222 1.0 1.0 3 Q06124 1
Frs mediated fgfr3 signaling 0.4493900455708288 0.2167096677359622 0.8284346132792222 1.0 1.0 3 Q06124 1
Frs mediated fgfr1 signaling 0.4493900455708288 0.2167096677359622 0.8284346132792222 1.0 1.0 3 Q06124 1
Nuclear receptor transcription pathway 0.2995120595478889 0.2158495318165645 0.8291050374534334 1.0 1.0 7 Q86WQ0 1
Toll like receptor 9 tlr9 cascade 0.35573604536137 0.2134814456002615 0.8309514598252545 1.0 1.0 26 P51452,P09429,P51617,Q13616,P27361,Q16539,P30153,O14733,O15111,Q14738,P30154,P52564,P28482,Q15750,Q13404,P63208 16
Rho gtpases activate cit 0.3097341001148559 0.2134402715118573 0.8309835719929579 1.0 1.0 10 P60660,Q7Z406,P61586 3
Pi3k akt signaling in cancer 0.321479854599183 0.2080682835105368 0.8351756512798256 1.0 1.0 14 P62993,P49815,Q96B36,P49840,Q06124 5
Membrane trafficking 0.2313836586875811 0.2069246544874938 0.8360687017007424 1.0 1.0 259 Q9H9Q2,P63167,P09497,P31946,Q9UJ41,Q8NC96,Q8IYI6,P62820,P31150,O14657,P40616,P61163,Q8TC07,Q14671,O14579,Q9UJY5,Q9UJY4,P53618,Q92747,P49815,Q9Y2L5,Q15436,Q9NV70,Q9Y6B7,Q9UBW8,Q92905,Q7L5N1,P33908,Q13409,Q92930,P49407,Q9NP79,Q8N6T3,Q04917,Q9UN37,Q9NZ52,Q9UP83,Q9UL25,Q9UJW0,P47755,Q9NZM3,Q15276,P59998,Q9Y6B6,O15027,P04350,Q07866,Q9BZE9,P62330,P55735,Q9H3P7,P18085,P68371,A5PLN9,Q8TAG9,P62993,O15498,Q13098,Q9BUF5,Q9NVG8,Q9NZZ3,O60343,Q9BXS5,P61160,Q9UNS2,O15145,O00401,Q9NZ32,P47756,O43237,O75351 71
Galactose catabolism 0.6417742841100611 0.2037849011672071 0.838521592379533 1.0 1.0 2 P51570 1
Nef mediated downregulation of mhc class i complex cell surface expression 0.3415002474714141 0.1971296188147739 0.843726105711021 1.0 1.0 5 Q9BXS5 1
Smac xiap regulated apoptotic response 0.6268950028074229 0.1782814955821949 0.8585019103956189 1.0 1.0 2 P55210 1
Activation of caspases through apoptosome mediated cleavage 0.6268950028074229 0.1782814955821949 0.8585019103956189 1.0 1.0 2 P55210 1
Gluconeogenesis 0.3244127851591833 0.173679282723863 0.8621175200511983 1.0 1.0 19 P04075,P00558,P09972,P06733,P17174 5
Fceri mediated ca 2 mobilization 0.2843530910601348 0.170022507627388 0.8649924358296626 1.0 1.0 7 P62993,O43865 2
Base excision repair 0.3488199774736559 0.1666574336695405 0.8676396000393187 1.0 1.0 31 P29372,P15927,P27695,Q15054,P18887,P12004,P39748 7
Pyroptosis 0.2826269321488013 0.1651927180612813 0.8687922966710986 1.0 1.0 7 P09429 1
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3380670726408102 0.1643087962671223 0.8694880573856358 1.0 1.0 26 O95394,Q96IJ6,O60547,Q9Y5P6,P53602,Q13630,Q9H553 7
Lysosome vesicle biogenesis 0.310885251705147 0.1605874757894885 0.872418319739324 1.0 1.0 16 Q9Y6B7,P49407 2
Met activates ptpn11 0.4176447129478279 0.1553703977842297 0.8765293198934372 1.0 1.0 3 Q06124 1
Metabolism of water soluble vitamins and cofactors 0.3606306653538342 0.1550568272024875 0.8767765173623392 1.0 1.0 45 O96007,P00374,Q8NFF5,O95396,P34896,Q96EN8,P43490,Q9NQX3,Q9NRN7,Q96CD2,P78417,O00763,Q9BQG2,Q13085,P05165,P50747,P11586,P49914,Q8NCW5 19
Repression of wnt target genes 0.3198442392508002 0.1488596541652251 0.8816643777391635 1.0 1.0 5 P56545,Q13363 2
Cholesterol biosynthesis 0.3086021483624819 0.1474377224030807 0.8827865326800275 1.0 1.0 17 P48449 1
Rho gtpases activate iqgaps 0.2930454541427973 0.1468633286342036 0.8832398975097355 1.0 1.0 12 Q9BUF5 1
Perk regulates gene expression 0.3076422138246568 0.1450955297311363 0.8846354476986622 1.0 1.0 17 Q96B26,P08243,Q9Y2L1,P41091 4
Trif mediated programmed cell death 0.6044357102751385 0.1439638530437774 0.8855290133293234 1.0 1.0 2 Q14790 1
Tlr3 mediated ticam1 dependent programmed cell death 0.6044357102751385 0.1439638530437774 0.8855290133293234 1.0 1.0 2 Q14790 1
Rab gefs exchange gtp for gdp on rabs 0.3332558739057755 0.1425391548014814 0.8866541540347583 1.0 1.0 28 Q9Y2L5,Q9UL25,Q9UJ41,P62258,P31150,Q15042,Q92930,P62820,Q9H2M9,A5PLN9 10
Runx2 regulates genes involved in cell migration 0.6030320044918709 0.1419856668661427 0.8870913271638077 1.0 1.0 2 Q13951 1
Signaling by met 0.3142850657044027 0.1412983503242087 0.8876342527912959 1.0 1.0 20 P40763,Q06124,P62330,P46109,Q96S59 5
Attenuation phase 0.2867366659104804 0.1393850067398762 0.8891459195923064 1.0 1.0 11 P08238,Q02790,P11142,P07900,Q15185,P25685,Q92598 7
Vesicle mediated transport 0.2186037830510401 0.1337870064158598 0.8935710021985321 1.0 1.0 264 Q9H9Q2,P63167,P09497,P31946,Q9UJ41,Q8NC96,Q8IYI6,P62820,P31150,O14657,P40616,P61163,Q8TC07,Q14671,O14579,Q9UJY5,Q9UJY4,P53618,Q92747,P49815,Q9Y2L5,Q15436,Q9NV70,Q9Y6B7,Q9UBW8,Q92905,Q7L5N1,P33908,Q13409,Q92930,P49407,Q9NP79,Q8N6T3,Q04917,Q9UN37,Q9NZ52,Q9UP83,Q9UL25,Q9UJW0,P47755,Q9NZM3,Q15276,P59998,Q9Y6B6,O15027,P04350,Q07866,Q9BZE9,P62330,P55735,Q9H3P7,P18085,P68371,A5PLN9,Q8TAG9,P62993,O15498,Q13098,Q9BUF5,Q9NVG8,Q9NZZ3,O60343,Q9BXS5,P61160,Q9UNS2,O15145,O00401,Q9NZ32,P47756,O43237,O75351 71
Parasite infection 0.3269613049049016 0.1329160230896824 0.8942597947480373 1.0 1.0 27 P27361,Q9UQB8,Q9Y6W5,P61160,O15145,O00401,Q92747 7
Crmps in sema3a signaling 0.3110424276482221 0.1318540316612258 0.895099748500799 1.0 1.0 5 Q9BPU6,Q16555,Q00535,O14531 4
Constitutive signaling by egfrviii 0.2985338097390787 0.1309770223872107 0.8957934842772999 1.0 1.0 6 Q16543 1
Signaling by egfr in cancer 0.2985338097390787 0.1309770223872107 0.8957934842772999 1.0 1.0 6 Q16543 1
Constitutive signaling by ligand responsive egfr cancer variants 0.2985338097390787 0.1309770223872107 0.8957934842772999 1.0 1.0 6 Q16543 1
Role of phospholipids in phagocytosis 0.3104804720427069 0.1308196130605179 0.8959180073535948 1.0 1.0 5 O43865,P19174,Q8IV08,Q14571 4
Regulation of pten localization 0.5934868051656501 0.1290498578864799 0.8973181977412843 1.0 1.0 2 P29590 1
Resolution of d loop structures 0.28871359876718 0.128775841696282 0.8975350218738221 1.0 1.0 13 Q9UQ84 1
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.28871359876718 0.128775841696282 0.8975350218738221 1.0 1.0 13 Q9UQ84 1
Host interactions of hiv factors 0.2725551047765222 0.1287616421124379 0.8975462579603517 1.0 1.0 96 P28070,P43487,P20618,O43242,P43686,O14818,Q13200,O00487,P62333,Q9UNM6,P28072,P60900,P35998,Q15008,Q15370,Q9UL46,P17096,P25787,P25788,P25789,P37198,P25786,P28066,O00233,P17980,P28074,P62195,P55735,P49720,P61289,P62826,P63208,O75832,O00231,O00232,Q99436,Q9BXS5,Q15369,P55036,P62191 40
Cilium assembly 0.3439677021499903 0.1279459122738362 0.8981917768632826 1.0 1.0 65 P63167,P48643,P07437,Q8IYI6,Q96KP1,Q15019,P61163,Q9H6D7,P50991,Q9H0F7,Q96EX3,Q9NV70,P30153,P17987,Q13409,O75665,P36405,P78371,P04350,P06493,P49368,O43805,P18085,P68371,Q8TAG9,Q9BW83,Q15691,P62258,Q9BUF5,Q96FJ2,P50990,P17612 32
Synthesis of pe 0.5892756878158469 0.123627071726355 0.9016105567738602 1.0 1.0 2 P35790 1
Mapk targets nuclear events mediated by map kinases 0.2766211293986477 0.1233861540120559 0.9018013207895106 1.0 1.0 10 P51452,P27361,Q16539,P30153,Q14738,P30154 6
Erk mapk targets 0.2766211293986477 0.1233861540120559 0.9018013207895106 1.0 1.0 10 P51452,P27361,Q16539,P30153,Q14738,P30154 6
Fasl cd95l signaling 0.5850645704660437 0.118376743087467 0.9057691525244024 1.0 1.0 2 Q14790 1
Downregulation of erbb2 erbb3 signaling 0.5845030881527364 0.1176896618454191 0.9063135585020704 1.0 1.0 2 P31751 1
Grb2 sos provides linkage to mapk signaling for integrins 0.391182252176353 0.1147189055875081 0.908667928369655 1.0 1.0 3 P62993,P12931 2
Ctla4 inhibitory signaling 0.2692669630961621 0.1145069759813289 0.9088359167404618 1.0 1.0 9 Q06124,P30153,P12931,Q14738,P30154 5
Effects of pip2 hydrolysis 0.3103932584269633 0.1122271844265992 0.9106432752666712 1.0 1.0 4 Q8NCG7,Q8N2K0,Q14571 3
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.2888083153330791 0.1095888328113775 0.9127354674371362 1.0 1.0 16 P50991,P48643,P78371,P19784,P40227,P67870,P17987,P50990,Q99832 9
Toll like receptor cascades 0.3274692988352624 0.1065395081321747 0.9151543108114676 1.0 1.0 35 P09429,P51617,Q06124,Q16539,O14733,P30154,Q99538,P28482,Q13404,P51452,P07858,P30153,P52564,Q14790,P27361,Q15750,P63208,O15111,Q14738 19
Platelet aggregation plug formation 0.2958696262995276 0.1060652940154593 0.9155305471404908 1.0 1.0 5 P62993,P12931,P41240,Q9Y490 4
Integrin signaling 0.2958696262995276 0.1060652940154593 0.9155305471404908 1.0 1.0 5 P62993,P12931,P41240,Q9Y490 4
Cellular responses to stimuli 0.2368652076120447 0.1055107374382085 0.9159705503041622 1.0 1.0 351 P62899,Q92945,P08243,P06400,Q16539,P00390,P18621,Q9Y6G9,P49840,P40763,Q9BX63,P20248,P35998,Q15008,P63220,P30044,P52564,Q13309,P17096,P05387,P37198,P28066,O00233,Q14145,P62266,P47755,P67870,P63173,Q13451,P62263,P30041,P61513,P08708,O75832,P05388,P05198,O95817,P31689,Q9BUF5,Q15369,P55036,P53004,P62857,P47756,Q9UNM6,P30050,Q15370,O95757,P25787,P25788,P25789,Q8N6T3,Q96B36,P62273,P62829,P55735,P49720,P62854,Q96EB6,Q96B26,Q06210,P62753,Q9Y3U8,Q15185,Q9UL15,O43237,P63167,P62280,P60866,P05386,O60884,O43242,O14818,O14733,O00487,P61163,P39019,P30043,P31948,P15927,P28072,P42771,P60900,P25398,P62249,P19784,Q86X55,Q13409,P83731,Q9Y2L1,P61927,P46777,Q9UJW0,P04350,P28074,P51858,P61289,P62847,P63208,P68371,Q99615,P15880,P11802,P08865,P62888,P23396,P27694,P62750,P62244,P62241,P24941,P28070,P50914,P32969,P20618,P46776,P43686,P46781,Q0VDF9,Q13200,P62333,Q16881,Q9UL46,P25786,P27361,P20042,P17980,P84098,P41091,P62195,P42766,O00231,Q99436,O00232,P32119,Q00534,P62841,P62701,P62277,P62258,P62913,P61247,P62191,Q9NZ32,Q92598 145
Copi mediated anterograde transport 0.3382300412124548 0.1049386280927497 0.9164245073829408 1.0 1.0 54 P63167,Q13561,P61163,Q9Y6G9,O14579,P53618,P35606,Q13409,P61923,Q8N6T3,Q9UP83,P48444,Q9UJW0,P47755,P04350,P18085,P68371,O15498,Q9BUF5,Q96FJ2,O43237,Q9NZ32,P47756,P62820 24
Protein folding 0.3301307567717479 0.0994202761197328 0.920804584503402 1.0 1.0 41 P48643,O75347,Q15477,Q99471,P50991,P40763,Q99426,P61758,P19784,P17987,Q9UHV9,P78371,P04350,P67870,P51784,Q9NQP4,P49368,Q99832,P68371,Q9BUF5,P40227,Q9Y2T2,P50990 23
Synthesis of pips at the plasma membrane 0.2833218002288492 0.0988924718305135 0.9212236462154696 1.0 1.0 16 Q13614,Q96PE3 2
Infectious disease 0.240161182607376 0.0984799560909546 0.9215511873069828 1.0 1.0 379 P62899,Q00403,P52657,P06400,P00558,Q16539,P18621,Q9Y6G9,Q9H9H4,P49840,P35998,Q15008,P63220,P29590,P52564,P17096,P10644,P05387,P37198,O43747,P28066,O00233,Q14145,P62266,P63173,Q9UQB8,P62263,P20839,P61513,P08708,P62081,O75832,P05388,Q8IXQ6,O00629,Q9BUF5,Q15369,P55036,P61160,P62857,O15145,Q96FJ2,Q13464,P17612,P39748,Q9H3P2,Q9HD42,Q99460,P35268,P32780,P28482,Q9UNM6,O43148,O15514,P30050,Q15370,P61254,P12268,Q08945,Q02878,P25787,P25788,P25789,P61353,P46782,P62273,Q99873,P62829,P59998,P06733,P55735,P49720,P62826,P62854,Q96PU5,Q9NZZ3,P62753,Q9Y2Z0,Q15185,Q9Y3U8,O00401,O43237,O75351,P63167,P62280,P60866,P07437,P05386,O43242,O14818,O14733,O00505,O00487,P39019,P18615,P28072,P60900,P25398,P62249,Q13409,Q9NP79,Q9UN37,P83731,Q96SB4,P61927,P46777,P04350,P28074,P61289,P62847,P63208,P68371,P62993,P15880,P08865,P62888,P23396,P62750,P62487,P62244,P62241,P28070,P50914,P32969,P43487,P20618,P46776,P43686,P46781,Q13200,P62333,Q92747,Q63HN8,Q16881,Q99816,Q9UL46,P25786,P18858,P27361,P19525,P17980,P84098,P13639,P13010,P62195,P49917,P42766,O43865,O00231,Q99436,O00232,P62841,P62701,P62277,P62913,Q9BXS5,P61247,Q9Y6W5,P62191 159
Transcriptional regulation by runx1 0.3091252820052573 0.0976273626523356 0.9222281960355714 1.0 1.0 77 P28070,P20618,Q06124,O43242,P43686,O14818,Q13200,O00487,P62333,Q9UNM6,P28072,P60900,P35998,P19784,Q9UL46,P25787,P25788,P25789,P25786,P28066,O00233,Q99873,Q12824,P17980,P17931,P28074,P62195,P49720,P61289,O00231,O75832,Q99436,Q16625,Q00534,P05771,P55036,P62191 37
Caspase mediated cleavage of cytoskeletal proteins 0.2600736084542576 0.0955607764291496 0.923869418455675 1.0 1.0 9 Q9UJU6,P55210,Q14790,P55212 4
Downregulation of erbb4 signaling 0.5640089837170272 0.094661202255351 0.9245839356592986 1.0 1.0 2 P12931 1
Runx1 regulates transcription of genes involved in bcr signaling 0.5637282425603736 0.0943729599629193 0.924812894745388 1.0 1.0 2 Q13951 1
Eph ephrin signaling 0.3213729954176959 0.0938802632440626 0.9252042722338324 1.0 1.0 36 Q7Z406,P23528,O43639,P59998,P61586,P61160,P60660,O00401,O15145,Q92747 10
Cell cycle mitotic 0.209207632241599 0.0924268511546966 0.9263589065963982 1.0 1.0 288 P00374,P06400,Q9Y6G9,Q99741,Q99640,P20248,Q15008,P35998,P33991,P30153,P28340,Q13309,P37198,P28066,O00233,Q9NR33,O75832,Q9BUF5,P63151,P55036,P49642,P17612,P39748,Q9Y570,Q86XI2,Q9BSJ2,Q9Y619,Q9UNM6,Q15003,O43684,P25787,P25788,O75665,P25789,Q8N0S6,Q9P258,P51530,P06493,P55735,P49720,P62826,P30307,Q9HBM1,Q9Y266,Q9UBD5,O43237,P63167,P07437,O43242,O14818,O00487,Q9Y248,P61163,Q9H6D7,P49643,P15927,P28072,O43929,P42771,P60900,P19784,Q96CW5,Q13409,Q5TKA1,Q9UN37,P04350,P28074,P61289,Q9BRX5,P63208,P68371,Q9H900,P11802,P05771,P27694,P62820,P24941,P28070,P20618,P43686,Q15054,Q13200,P62333,Q8NBT2,Q96EA4,Q9BRT9,Q9UL46,P12004,Q9HC35,P25786,P18858,P04183,P27361,P17980,Q01105,P62195,O43805,Q99986,O00231,O00232,Q99436,P31350,Q00534,Q15691,P62258,P35250,P62191 107
Receptor type tyrosine protein phosphatases 0.5595171252105703 0.090135484114858 0.9281795517253092 1.0 1.0 2 Q13136 1
Tnfr1 induced proapoptotic signaling 0.2833537071725691 0.0880689953614764 0.92982183871919 1.0 1.0 5 Q13107,Q14790 2
Interleukin receptor shc signaling 0.5572711959573421 0.0879410640621261 0.9299235186147828 1.0 1.0 2 P62993 1
Map3k8 tpl2 dependent mapk1 3 activation 0.2738078482700165 0.0876898379488717 0.9301231966511544 1.0 1.0 6 O15111,P63208,Q13616 3
Runx2 regulates bone development 0.2516967769290474 0.0860801424421439 0.9314027090593991 1.0 1.0 8 P27361,P06400 2
Gpvi mediated activation cascade 0.2724718462194522 0.0857127085891149 0.9316947993165996 1.0 1.0 6 Q06124 1
Polymerase switching on the c strand of the telomere 0.2774304375960652 0.0836554131076417 0.9333304080095676 1.0 1.0 17 P49643,Q15054,P35250,P49642,P12004 5
Fcgamma receptor fcgr dependent phagocytosis 0.3141353001929243 0.081170343091805 0.935306484454112 1.0 1.0 37 P16333,P08238,P28482,Q92747,P60953,P35240,P23528,P27361,P59998,Q9UQB8,O43865,P62993,Q9NZQ3,Q9Y2A7,P12931,Q9Y6W5,P61160,O15145,O00401 19
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.2916360717756703 0.0794878725929676 0.9366445773599495 1.0 1.0 24 P14174,O00170,Q99439,P23528,P78417,P26038,Q13126,Q00169,P05388 9
Post translational protein modification 0.2084079846623024 0.0793859432520219 0.9367256490133212 1.0 1.0 439 Q9H9Q2,Q9HA64,Q9Y5T5,O60678,P54578,O14579,P53618,P20248,Q5TAQ9,Q9UBW8,Q70CQ2,P35998,Q92905,P33908,Q13309,P53602,P49407,P28066,O00233,Q9UP83,Q96FW1,Q9UL25,P47755,O95999,Q9H2P9,Q9Y6B6,Q04323,P26358,P18085,O75832,O95630,O15498,Q9UPT9,Q9BUF5,P61586,Q15369,P61081,P63241,P55036,P49366,P47756,P49427,Q99497,Q8TBC4,Q9BQC3,Q13564,Q96IJ6,Q15370,P25787,P25788,P25789,Q8N6T3,Q14118,O15027,P06493,P49720,Q13630,Q9H0A8,O43237,O95394,Q96GG9,Q9Y4E8,O60547,P42771,P60900,Q7L5N1,Q13409,Q92930,Q9H553,Q9Y5P6,Q14166,P04350,P28074,P61289,P63208,Q9BU89,Q9NR45,Q9NZJ0,Q9NZL9,P28070,P20618,Q13200,P62333,Q92696,Q9NX08,Q9ULX3,Q9NXR7,P12004,P25786,O60493,P62195,Q99436,Q13363,Q13098,Q9Y5K5,P62191,Q9NZ32 97
Transport to the golgi and subsequent modification 0.2862142822715753 0.0788742235567582 0.9371326659737532 1.0 1.0 81 P63167,P62820,Q13561,Q9Y6G9,P61163,O14579,P53618,Q15436,P35606,P33908,P61923,Q13409,Q8N6T3,Q9UP83,P48444,Q9UJW0,P47755,P04350,Q9Y6B6,O15027,P55735,P56962,P18085,O00743,P68371,O15498,Q9BUF5,Q96FJ2,Q9NZ32,P47756,O43237 31
Clathrin mediated endocytosis 0.3175974792295408 0.0778861628042996 0.9379186064548656 1.0 1.0 59 Q9H9Q2,Q8N6T3,P09497,Q13098,Q8NC96,Q9UNS2,Q9UBW8,Q9NZM3,P59998,Q92905,O14657,Q7L5N1,P61160,P62330,O15145,O00401,Q92747,P49407 18
Interferon alpha beta signaling 0.2534281374120648 0.0777651344759396 0.938014881087878 1.0 1.0 10 Q13325,Q06124 2
Cell cycle 0.1561706686813137 0.0776792856149394 0.9380831719929345 1.0 1.0 344 Q8N2W9,P00374,P06400,Q9Y6G9,Q9BX63,Q99741,Q99640,P20248,P35998,Q15008,P33991,P30153,P28340,Q13309,P37198,P28066,O00233,Q9NR33,O75832,Q9UQ84,Q9BUF5,P63151,P55036,O96017,P49642,P17612,P39748,Q9Y570,Q86XI2,Q9BSJ2,Q9Y619,Q9UNM6,Q15003,O43684,P25787,P25788,P25789,O75665,Q8N0S6,Q9P258,P51530,P06493,P55735,P49720,P62826,P30307,Q9HBM1,Q9Y266,Q9UBD5,O43237,P63167,P07437,O43242,O14818,Q9Y248,O00487,Q9H6D7,P61163,P49643,P15927,O43929,P42771,P60900,P28072,P19784,Q96CW5,Q13409,Q5TKA1,Q04917,Q9UN37,P04350,P28074,P61289,Q9BRX5,P63208,P68371,Q9H900,P11802,P05771,P27694,P62820,P62487,P24941,P28070,P20618,P31946,P43686,Q15054,Q13200,P62333,Q8NBT2,Q96EA4,Q9BRT9,Q9NXR7,Q9UL46,P12004,P25786,Q9HC35,P18858,P04183,P27361,P17980,Q01105,P62195,O43805,Q99986,O00743,Q99436,O00231,O00232,P31350,Q00534,Q15691,P62258,P62191,P35250 116
Nuclear events kinase and transcription factor activation 0.2625202262190674 0.0776748418050708 0.9380867069596062 1.0 1.0 13 P51452,P27361,Q00535,Q16539,P30153,Q14738,P30154 7
Gap junction degradation 0.2661607644744317 0.076856548704058 0.9387376643662008 1.0 1.0 6 Q9UM54,P09497,P50570,P09496,Q00610 5
Recruitment of mitotic centrosome proteins and complexes 0.3090418461586133 0.0758333143537971 0.9395517114043888 1.0 1.0 36 P63167,P07437,Q15691,P62258,P04350,P17612,Q96CW5,P06493,Q9BSJ2,P61163,O75665,O43805,Q9H6D7,Q13409,P68371 15
Signaling by tgf beta receptor complex 0.2880344785654153 0.0742385325259212 0.9408205859067416 1.0 1.0 24 Q96PU5,P27361,Q13485,P61586,P61081,Q9Y5K5,Q9Y3F4,Q9Y4E8 8
Trna aminoacylation 0.3106719119331068 0.0737836481524266 0.9411825384403149 1.0 1.0 39 Q9NSD9,Q9H2U2,P54136,P54577,P26640,Q15046,Q13155,O43776,P56192,P41250,P23381,P41252,P49589,Q9P2J5,Q15181,Q96GW9,P14868,Q12904,P26639,P49591,O43324 21
Prevention of phagosomal lysosomal fusion 0.3541140129177175 0.0731598831211295 0.9416788894345394 1.0 1.0 3 P20339,Q9H267 2
Runx1 regulates estrogen receptor mediated transcription 0.5384615384615539 0.0712988335185006 0.943159923585998 1.0 1.0 2 Q13951 1
Raf activation 0.2623037278169569 0.0686630204637734 0.9452578540978545 1.0 1.0 15 Q02750,P31946,P30153,P12931,P10398,P36873,Q14738,P30154 8
Extension of telomeres 0.3018921589087092 0.0683635888412659 0.9454962058882356 1.0 1.0 35 P49643,P24941,P15927,P27694,P20248,Q15054,P51530,P35250,P49642,P12004,O00743,P39748,P18858 13
Signaling by tgfb family members 0.2856610445185792 0.0682247996853911 0.9456066856679703 1.0 1.0 25 Q96PU5,P27361,Q13485,P61586,P61081,Q9Y5K5,Q9Y3F4,Q9Y4E8 8
Rho gtpases activate pkns 0.2747497918237239 0.0682133597023062 0.9456157922389016 1.0 1.0 20 Q04917,Q7Z406,P31946,P62258,P61586,Q16513,P60660,P27348,P30307 9
Er to golgi anterograde transport 0.2802498801631557 0.0672050058535767 0.9464185000417992 1.0 1.0 78 P63167,P62820,Q13561,Q9Y6G9,P61163,O14579,P53618,Q15436,P35606,P61923,Q13409,Q8N6T3,Q9UP83,P48444,Q9UJW0,P47755,P04350,Q9Y6B6,O15027,P55735,P56962,P18085,O00743,P68371,O15498,Q9BUF5,Q96FJ2,Q9NZ32,P47756,O43237 30
Antigen activates b cell receptor bcr leading to generation of second messengers 0.2630759527380407 0.0648256819463283 0.9483127932171712 1.0 1.0 5 P62993,O43865 2
Anchoring of the basal body to the plasma membrane 0.2988674961839462 0.0635464863792446 0.9493313432402146 1.0 1.0 36 P63167,P07437,Q15691,P62258,P04350,P17612,P06493,Q15019,P61163,O75665,O43805,Q9H6D7,Q13409,P68371 14
Calcineurin activates nfat 0.5275126333520654 0.0629765427159227 0.9497851834357796 1.0 1.0 2 Q08209 1
Activated ntrk2 signals through fyn 0.5263896687254512 0.0621770138428947 0.95042186736102 1.0 1.0 2 P12931 1
Nef and signal transduction 0.5263896687254511 0.0621770138428947 0.95042186736102 1.0 1.0 2 Q13177 1
Met activates ras signaling 0.2593969513093682 0.0613405592993283 0.951087989950694 1.0 1.0 5 P62993,Q96S59 2
Organelle biogenesis and maintenance 0.1732132426247893 0.0595383983902247 0.952523282215249 1.0 1.0 98 Q8WVM0,P63167,P48643,P07437,Q8IYI6,Q96KP1,Q16539,Q15019,P61163,Q9H6D7,P50991,Q9H0F7,Q96EX3,Q9NV70,P30153,Q86X55,P17987,Q13409,O75665,P48735,P78371,P36405,P04350,P06493,P49368,P18085,O43805,P68371,Q8TAG9,Q9BW83,Q15691,P62258,Q9BUF5,Q96FJ2,P50990,P17612 36
Hsf1 dependent transactivation 0.2581202861667628 0.0593770628066733 0.9526517820477698 1.0 1.0 16 Q96B36 1
Signaling by braf and raf1 fusions 0.28369931091631 0.0591996199025818 0.9527931123871088 1.0 1.0 28 P31946,P27361,P41240,Q96PU8,O95352,P10398,O43252,P49407 8
Interleukin 12 family signaling 0.2835860333399006 0.0572969744258559 0.9543086304540512 1.0 1.0 29 P14174,O00170,Q99439,P40763,P23528,P78417,P26038,Q13126,Q00169,P05388 10
Disorders of transmembrane transporters 0.2693198672463486 0.0553427101440239 0.955865436510236 1.0 1.0 74 P28070,P20618,O43242,O14818,Q13200,P62333,O00487,O75477,Q9UNM6,P60900,P35998,P25787,P25788,P25789,P25786,P28066,O00233,P28074,P62195,P55735,P49720,P61289,O75832,Q99436,P55036,P62191 26
Recruitment of numa to mitotic centrosomes 0.2931725995952899 0.0550277988839783 0.9561163170332992 1.0 1.0 39 P63167,P07437,Q15691,Q9BUF5,P04350,P17612,Q96CW5,P06493,Q9BSJ2,P61163,O75665,O43805,Q9H6D7,Q13409,P68371 15
Atf4 activates genes in response to endoplasmic reticulum stress 0.249188558492823 0.0548338668148816 0.9562708191638232 1.0 1.0 14 Q96B26,Q9Y2L1 2
Intra golgi and retrograde golgi to er traffic 0.2047235414048354 0.0539263829675927 0.9569938166758708 1.0 1.0 88 P63167,P62820,Q13561,Q15042,Q9Y6G9,P40616,P61163,O14579,P53618,O43264,P35606,P33908,P61923,Q13409,O60333,Q9H2M9,Q8N6T3,Q9UP83,P48444,Q9UJW0,P47755,P04350,P68402,Q07866,P18085,P68371,O15498,Q9BUF5,Q96FJ2,Q9NZ32,P47756,O43237 32
Fceri mediated mapk activation 0.2399597889399317 0.0537857845811422 0.9571058353858573 1.0 1.0 11 P62993,P27361,O14733,P28482 4
Interleukin 12 signaling 0.274458109060481 0.0530707397372441 0.9576755448939408 1.0 1.0 26 P14174,O00170,Q99439,P23528,P78417,P26038,Q13126,Q00169,P05388 9
Trans golgi network vesicle budding 0.2843046274019158 0.0483055779149438 0.9614727092120527 1.0 1.0 38 Q9Y6B7,Q8NC96,P49407,Q14671 4
Cargo recognition for clathrin mediated endocytosis 0.2821636392024774 0.0479210082412875 0.9617791964679692 1.0 1.0 36 Q9H9Q2,P09497,Q13098,Q8NC96,Q9UBW8,Q9NZM3,Q92905,O14657,Q7L5N1,Q9UNS2,P49407 11
Rhov gtpase cycle 0.2591483990932859 0.0474328012006072 0.9621682868547508 1.0 1.0 21 O00401,O43639 2
Ddx58 ifih1 mediated induction of interferon alpha beta 0.2606624291570368 0.0469294028248213 0.9625694938392008 1.0 1.0 22 P09429,Q9H1Y0,Q15366,Q14258,Q13526,O15111,P61086,Q3LXA3 8
Propionyl coa catabolism 0.3162033136759372 0.0468274258770911 0.9626507703162216 1.0 1.0 3 P05166,P05165 2
Regulation of tp53 activity through phosphorylation 0.2840180155312509 0.0467891914492057 0.9626812435739036 1.0 1.0 41 Q13131,P15927,Q9UQ84,Q13526,Q96S44,O96017 6
Smooth muscle contraction 0.2339466843842289 0.0466746809817693 0.962772509996265 1.0 1.0 11 P67936 1
Resolution of sister chromatid cohesion 0.1658513847449381 0.0450117640210047 0.9640979321263216 1.0 1.0 75 Q9H900,Q9P258,Q9HBM1,Q9BUF5,P04350,O43684,P06493,Q13409,O43237,Q8N0S6 10
Autophagy 0.2734935499097433 0.0447333265309442 0.9643198695470314 1.0 1.0 58 Q8NCE2,P63167,Q13131,Q99497,P08238,O95352,Q9Y6G9,Q9Y4P8,Q13404,O75143,Q9H9H4,P49815,Q99816,P19784,Q9NT62,Q13409,P13473,Q676U5,P50542,P54619,P04350,P67870,P68371,Q9Y4P1,Q9H1Y0,Q9BUF5,Q96FJ2,Q9BVA1,Q9Y484,O43237 30
Rho gtpases activate formins 0.2009532373822477 0.0446415664993144 0.9643930103931102 1.0 1.0 74 Q9H900,P35080,Q9P258,Q9HBM1,Q9BUF5,P04350,O43684,P07737,Q13409,O43237,Q8N0S6 11
Defects in vitamin and cofactor metabolism 0.2348226712490184 0.0446275403266624 0.9644041905174034 1.0 1.0 12 Q99707,Q96EY8,Q96RQ3,Q13085,P05165,P50747 6
Oncogenic mapk signaling 0.2749143191947248 0.0438889498151699 0.96499292358457 1.0 1.0 34 P30086,P31946,P27361,P41240,Q99956,O95352,Q96PU8,P10398,O43252,P49407 10
Regulation of plk1 activity at g2 m transition 0.2785587420000983 0.0437988128962849 0.9650647733493884 1.0 1.0 39 P63167,P07437,Q13561,P61163,Q9H6D7,P30153,Q13409,O75665,Q7Z460,P04350,P06493,O43805,P63208,P68371,Q13616,Q15691,P62258,P07900,O95067,P17612,O14965 21
Golgi to er retrograde transport 0.2209197377368893 0.0434123764678256 0.9653728120084856 1.0 1.0 71 P63167,Q13561,Q15042,Q9Y6G9,P61163,O14579,P53618,O43264,P35606,Q13409,P61923,P52907,O60333,Q9H2M9,Q8N6T3,P48444,Q9UJW0,P47755,P04350,P68402,Q07866,P18085,P68371,Q9BUF5,Q96FJ2,Q9BVA1,O43237,Q9NZ32,P47756,P62820 30
Microrna mirna biogenesis 0.2354027446194329 0.0424926399343129 0.9661059789343164 1.0 1.0 13 O75569 1
Neurotransmitter receptors and postsynaptic signal transmission 0.276291805866172 0.04182004924626 0.9666421520062514 1.0 1.0 46 Q92796,Q13131,Q9BUF5 3
Metabolism of vitamins and cofactors 0.2689051475410527 0.0415689714794693 0.9668423090240724 1.0 1.0 55 O96007,P00374,Q96CD2,Q5T2R2,Q96EN8,P50747,P43490 7
Regulation of tp53 activity 0.2345635311081045 0.0412078368682861 0.9671302060637 1.0 1.0 66 Q13131,P15927,P42771,Q9UQ84,Q96S44,P06493,P52564,O96017 8
Dna double strand break repair 0.2234008305089434 0.0410158036613109 0.9672832969640652 1.0 1.0 67 P24941,P15927,P20248,Q9UQ84,Q9NR33,Q9NXR7,Q15054,Q96B01,P18887,O96017,Q04323,P53041,P49917,P12004,P39748 15
Selective autophagy 0.270583698883287 0.040924933187033 0.9673557402863446 1.0 1.0 34 Q9H1Y0,Q99497,Q9BUF5,Q13409,Q13404,O43237 6
Neuronal system 0.1863311156056125 0.0407424167912551 0.9675012459425804 1.0 1.0 68 Q92796,Q13131,Q9BUF5 3
Mhc class ii antigen presentation 0.2575421073532851 0.0398974042183604 0.9681749205907196 1.0 1.0 58 P63167,Q13561,Q99538,Q9Y6G9,P61163,Q15436,P07858,Q13409,P52907,O43747,Q9UJW0,P47755,P04350,Q9Y6B6,Q07866,P55735,P68371,Q9BUF5,Q9BXS5,Q96FJ2,Q9BVA1,Q99661,Q9NZ32,P47756,O43237 25
Hdr through homologous recombination hrr 0.2648286691266457 0.0398586347200413 0.9682058295884668 1.0 1.0 30 Q9BX63,P15927,Q9UQ84,Q9NR33,Q15054,Q96B01,P51530,P35250,P12004,P27694 10
Aurka activation by tpx2 0.2691683295102716 0.0395295102745048 0.9684682261009944 1.0 1.0 35 P63167,P07437,Q15691,P62258,P04350,P17612,P06493,P61163,O75665,O43805,Q9H6D7,Q13409,P68371 13
Hats acetylate histones 0.2660032572319101 0.0391841760636756 0.9687435496194609 1.0 1.0 32 O14929,Q9UPT9,Q9NS73,Q9H9T3,Q96EB1 5
Peptide hormone metabolism 0.2390630967306992 0.0390127102211454 0.9688802550378262 1.0 1.0 16 Q9NV70 1
Fatty acid metabolism 0.2570747027009164 0.036766067359516 0.9706715300703312 1.0 1.0 52 Q8N8N7,Q14914 2
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.4769792251544259 0.0357987301869722 0.9714428455835478 1.0 1.0 2 Q13555 1
Transmission across chemical synapses 0.230219785172228 0.0353947961231753 0.9717649342057828 1.0 1.0 57 Q92796,Q13131,Q9BUF5 3
Nucleotide excision repair 0.1972930231405648 0.0352980322974386 0.9718420923537954 1.0 1.0 59 Q9H9Q2,Q86WJ1,Q9BT78,Q15054,P32780,P15927,Q9UBW8,Q92905,P28340,Q7L5N1,P12004,P18858,Q9NR33,P18887,P54727,Q92889,Q13098,Q16531,P35250,Q9UNS2,P27694,P62487 22
Diseases of dna repair 0.2363937971626171 0.0349726501534072 0.9721015495433604 1.0 1.0 17 Q9UQ84 1
Homologous dna pairing and strand exchange 0.2428152965319982 0.0339525062927995 0.9729150233319026 1.0 1.0 21 Q96B01,Q9UQ84 2
Downregulation of smad2 3 smad4 transcriptional activity 0.2111022696414957 0.0323151648015384 0.9742207157581144 1.0 1.0 8 Q96PU5 1
Transcription of the hiv genome 0.2531692344709043 0.0321511317120011 0.9743515272549236 1.0 1.0 32 P52657,Q15369 2
Homology directed repair 0.2195223991396079 0.0317947194213842 0.9746357578003572 1.0 1.0 52 Q8N2W9,P24941,Q15054,Q9BX63,P15927,P20248,Q9NXR7,Q9NY27,P28340,P12004,Q9NR33,P18887,P51530,P60510,Q9UQ84,Q96B01,P35250,P27694,P39748 19
Transcription coupled nucleotide excision repair tc ner 0.2310093092499235 0.0310198049336707 0.9752537452190402 1.0 1.0 49 Q9H9Q2,Q9BT78,Q15054,P32780,P15927,Q9UBW8,Q92905,P28340,Q7L5N1,P12004,P18858,Q9NR33,P18887,Q92889,Q13098,Q16531,P35250,Q9UNS2,P27694,P62487 20
Metabolism of steroids 0.2094989052288851 0.03017407463119 0.9759282245614168 1.0 1.0 50 Q9Y6B6,Q86X55,Q03426,P48449,P62826,P53602 6
Leishmania infection 0.1764883401923501 0.0283657628699129 0.9773704304789048 1.0 1.0 48 P27361,Q9UQB8,Q9Y2Z0,O15145,O00401,P17612,Q92747 7
Sumoylation of transcription factors 0.2061304836895374 0.0282050842497711 0.9774985821939112 1.0 1.0 8 Q8N2W9,Q13330,P04637,P42771,O75928,Q12888,P61956 7
L1cam interactions 0.2238527597477718 0.0272630261893328 0.9782499467259018 1.0 1.0 43 O00560,O95372,Q92796,Q96P70,P27361,P19784,P15311,P26038,P04350,P67870,Q9BUF5,Q16555,Q9BVA1,P28482,Q15334,P68371,Q96S59 17
Costimulation by the cd28 family 0.2233676154012504 0.0262748570332092 0.9790381091671464 1.0 1.0 17 P62993,P60953,P41240,Q06124,P30153,P12931,Q14738,P30154,Q13177 9
Tp53 regulates metabolic genes 0.2244819677453766 0.0250755078588205 0.9799947359357616 1.0 1.0 38 Q13131 1
G2 m dna damage checkpoint 0.1653049388895104 0.0246285616726203 0.9803512372854444 1.0 1.0 42 Q9UQ84,O96017,P06493,P30307 4
The role of nef in hiv 1 replication and disease pathogenesis 0.2081103914390385 0.021988662540738 0.982456999334645 1.0 1.0 13 P63000,Q9BXS5,P53680,P04439,Q9UI12,Q10567,Q96CW1,P63010,P56377,O43747,O94973,Q13177 12
Signaling by egfr 0.2058727743472982 0.0218444830062732 0.9825720103337904 1.0 1.0 12 P62993,Q06124,Q13685,P41240,Q99961,P60953 6
Response to elevated platelet cytosolic ca2 0.2105841932876681 0.0217675217325293 0.9826334019482303 1.0 1.0 34 P04075,Q01518,P23528,P05771,O43852,P37802,Q9NTK5,O75083,P07737,Q9UNF1,Q92520 11
Signaling by alk in cancer 0.2010675467160689 0.0209623452933908 0.983275693173416 1.0 1.0 34 P62993,Q63HN8,P40763,Q13616,P06753,P27361,P67936,P26038,P31939,P62753,Q07866,P28482,P10644,Q9HC35,P63208,P26641 16
Diseases of mitotic cell cycle 0.2107716186748686 0.0201896776598794 0.983892062242907 1.0 1.0 17 P06400,P24941,Q00534 3
Protein ubiquitination 0.2105985022708734 0.0189719704249944 0.9848634657450808 1.0 1.0 25 O95999 1
Regulation of tp53 activity through acetylation 0.2045444043391712 0.0187683084380915 0.9850259355708936 1.0 1.0 15 P52564 1
Copii mediated vesicle transport 0.1511891279728134 0.0184468414475361 0.9852823847178054 1.0 1.0 32 O94979,P53634,O95486,Q13190,O95487,Q15436,Q9HCU5,Q5H9R7,Q9H0V9,Q8WVM8,Q9Y296,Q99747,P54920,O60763,Q9UPN7,Q12907,Q08379,Q9Y6B6,O15027,P46459,P49755,O75396,P55735,Q8IUR0,P56962,O00743,Q9Y6Y8,O15498,P53992,P62820,P49257 31
Rab geranylgeranylation 0.2070493437193263 0.0180080202186244 0.9856324552400866 1.0 1.0 20 Q92696,Q9UL25,Q92930,P62820 4
Ksrp khsrp binds and destabilizes mrna 0.2014919282977274 0.0175916201199111 0.985964641819464 1.0 1.0 15 Q96B26 1
Type i hemidesmosome assembly 0.3705783267827236 0.0169428563453283 0.9864822032465704 1.0 1.0 2 Q03001 1
Mitochondrial trna aminoacylation 0.2023137697516966 0.01678109746562 0.9866112498121536 1.0 1.0 20 Q9H2U2,P26640,Q15046,Q5ST30,Q5T160,Q6PI48,Q9Y2Z4,P41250,Q9BW92,Q5JPH6,Q96GW9,Q9NP81,Q9UGM6,Q96I59,Q15031,Q7L3T8,Q9NSE4,P47897,Q5JTZ9 19
Pexophagy 0.3548568220101208 0.0162894415552105 0.9870034808437308 1.0 1.0 2 P50542 1
Semaphorin interactions 0.1964468551498175 0.0160802738852344 0.9871703506407484 1.0 1.0 23 P60660,Q7Z406,P23528,Q00535 4
Recycling pathway of l1 0.1744995245351054 0.0139074549211462 0.9889038141385648 1.0 1.0 23 P35241,P15311,P04350,P26038,Q9BUF5,P12931,Q16555,Q9BVA1,P28482,P68371 10
Hdr through single strand annealing ssa 0.1538882089445423 0.011997830083185 0.9904273462746508 1.0 1.0 21 Q9BX63,P15927,Q9UQ84,P51530,P35250,P27694 6
Rhou gtpase cycle 0.1613951965241921 0.0117347079358606 0.9906372725927924 1.0 1.0 20 P62993,P60953,P16333,Q03001,Q9NZM3,O43639,O43396,Q13177 8
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.1726571982887886 0.010238782416051 0.9918307763226444 1.0 1.0 12 P27361,Q96PU5 2
Foxo mediated transcription 0.1208818859841742 0.0067787354226334 0.99459139308659 1.0 1.0 13 Q96EB6,Q9Y3B8,P31751,P31946,Q13485,P27348 6