msigdb_reactome/result.tsv

Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
Eukaryotic translation initiation	0.5201010733756313	4.888851829942161	1.0142579753930886e-06	0.0014392103974013	0.0007201231625298	104	P15880,P05198,P56537,P62847,Q14232,P05387,Q13347,P62841,P83731,Q13144,P62269,P08865,P62913,P18621,P62081,Q07020,P30050,P63220,Q9Y3U8,P61313,Q9UBQ5,P61513,O60841,Q9NR50,P35268,P60842,P08708,P42766,P05388,P39019,P62244,P50914,P46777,P49770,P40429,P62910,P84098,P32969,P46778,P62899,P46776,P62857,Q15056,P63173,Q14240,P61254,P62906,P20042,O75821,P06730,O00303,P62273,P61927,P62249,P62753,P62888,O15372,P62854,P05386,P62701,P60866,P62829,P26373,P62280,P62277,P62263,P61247	67
Response of eif2ak4 gcn2 to amino acid deficiency	0.5307296560898968	4.616394898724937	3.90463626631643e-06	0.0055292514296902	0.0017713019597668	79	P15880,P05198,P62847,P05387,P62841,P83731,P08865,P62913,P18621,P62081,Q07020,P63220,Q9Y3U8,P61313,P61513,P35268,P05388,P08708,P08243,P42766,P39019,P62244,P50914,P46777,P40429,P62910,P84098,P32969,P46778,P62899,P46776,P62857,P63173,P61254,P62906,P20042,P62273,P62249,P62753,P30050,P61927,P60866,P62888,P62854,P05386,P62829,P62701,P62280,P26373,P62277,P62263,P61247	52
Neddylation	0.5263688762067223	4.562927688089924	5.044519292729532e-06	0.0071376406424544	0.0017713019597668	79	P49720,P25787,Q9UBW8,Q9UNS2,O00487,O75147,P48556,Q15369,Q13200,Q9NX08,O00233,Q9BT78,Q9UNM6,Q92905,Q96GG9,Q9UL46,Q86VX2,P63208,P20618,Q15370,P25788,P61081,Q9H2C0,P17980,O75832,P28072,P28074,P61289,P28066,Q7L5N1,Q13098,P62333,Q13564,P25789,Q8TBC4,P61962,Q06323	37
Synthesis of dna	0.4834811423776693	4.515438575861707	6.3185859839887115e-06	0.0089322883963818	0.0017713019597668	90	P49720,P35244,P25787,P12004,Q9UBD5,Q9UJX4,Q9UJX6,Q13042,P40937,O00487,Q9BRX5,P48556,P28070,P20248,Q13200,O00233,O43913,Q9UNM6,Q9Y248,P62191,Q9UL46,P63208,P20618,Q99741,Q9NR33,P25788,Q15054,P39748,Q96DE5,P17980,Q9BRT9,O75832,P28072,P28074,P61289,P28066,P25786,O43929,P62333,P24941,P25789,P15927,Q06323,P49643,Q13309,P18858	46
Eukaryotic translation elongation	0.5188130390513965	4.469703750416469	7.832801188323302e-06	0.0110609935950418	0.0017713019597668	79	P15880,P62847,P05387,P62841,P83731,P08865,P62913,P18621,P62081,Q07020,P63220,Q9Y3U8,P61313,P61513,P35268,P05388,P08708,P42766,P62244,P39019,P50914,P46777,P24534,P40429,P62910,P84098,P32969,P46778,P62899,P46776,P62857,P63173,P61254,Q05639,P62273,P62249,P62753,P62906,P30050,P61927,P60866,P62888,P62854,P05386,P62829,P62701,P62280,P26373,P62277,P62263,P61247	51
Mitotic g1 phase and g1 s transition	0.4967297444740373	4.446408823565625	8.731770224201796e-06	0.0123226148943885	0.0017713019597668	85	P49720,P35244,P00374,P11802,P25787,P12004,P04183,Q9UBD5,O00487,P48556,P28070,P20248,Q13200,O00233,O43913,P07948,Q9UNM6,P31350,P62191,Q9UL46,P63208,P20618,Q99741,Q9NR33,P25788,P42771,P17980,O75832,P28072,P28074,P61289,Q5TKA1,P63151,P28066,P25786,O43929,P62333,P25789,P15927,P06493,Q06323,P49643,Q13309,P24941	44
Cellular response to starvation	0.4727587946079583	4.390994230629172	1.12833534859913e-05	0.0158947756615726	0.0020027952437636	93	P15880,Q9Y664,P05198,P62847,P05387,P62841,P83731,P08865,P62913,P18621,P62081,Q07020,Q9Y2Q5,Q8NFG4,P63220,Q9Y3U8,P61313,P61513,P35268,P61421,P05388,P08708,P08243,P42766,P39019,P62244,P50914,P46777,P40429,P62910,P84098,P32969,P46778,P62899,P46776,P62857,P21283,P63173,P61254,P62906,P20042,P62273,P62249,P62753,P30050,P61927,P60866,P62888,P62854,P05386,P62829,P62701,P62280,P26373,P62277,P62263,P61247	57
Selenoamino acid metabolism	0.4627622053920486	4.265003000845642	1.9989951507648485e-05	0.0279869171201405	0.0031539701267624	92	P62847,P62841,P08865,P62913,Q16881,Q12904,P18621,P62081,Q07020,P63220,Q9Y3U8,P61313,P61513,P57772,P05388,P08708,P00390,Q96I15,P42766,P62244,P50914,P46777,P62910,P84098,P32969,P46778,P62899,P46776,P62857,P63173,O43324,P61254,P62906,P62273,P62249,P62753,P30050,P60866,P61927,P62888,P62854,P05386,P62829,P26373	44
Srp dependent cotranslational protein targeting to membrane	0.456414085079587	4.16019606004034	3.1797451509607555e-05	0.0441488692451044	0.0045152381143644	93	P37108,P49458,P62847,P62841,P08865,P62913,P18621,P62081,P09132,Q07020,Q9Y3U8,P63220,P61313,P61513,P05388,P08708,P42766,P62244,P39019,P50914,P46777,P60059,P62910,P84098,P32969,P46778,P62899,P46776,P62857,P51571,P63173,P61254,P62906,P62273,P62249,P62753,P61009,P04844,P61927,P30050,P60866,P62888,P62854,P05386,P62829,P62701,P62280,P26373,P62277,P62263	50
Dna replication	0.4554118204389509	4.102101875257897	4.094139255150786e-05	0.0564802366593145	0.0046032951269488	96	P49720,P35244,P25787,P12004,Q9UBD5,Q9UJX4,Q9UJX6,Q13042,P40937,O00487,Q9BRX5,P48556,P28070,P20248,Q13200,O00233,O43913,Q9UNM6,Q9Y248,P62191,Q9UL46,P63208,P20618,Q99741,Q9NR33,P25788,Q15054,P39748,Q96DE5,P17980,Q9BRT9,P16104,O75832,P28072,P28074,P61289,P28066,P25786,O43929,P62333,P24941,P25789,P15927,Q06323,P49643,Q13309,P18858	47
Fceri mediated nf kb activation	0.5559219166087114	4.095401453705857	4.2143746574518914e-05	0.0580898406547615	0.0046032951269488	48	P49720,P25787,O00487,P48556,Q13200,O00233,P07948,Q9UNM6,P62191,Q9UL46,P63208,P20618,O95999,P25788,Q15750,P17980,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,Q06323,P49427,Q9UDY8	27
Cyclin a cdk2 associated events at s phase entry	0.5564583632299167	4.087575952272646	4.3590398689730137e-05	0.0600228525771081	0.0046032951269488	47	P49720,P25787,P11802,O00487,P48556,P28070,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,P17980,O75832,P28072,P28074,P61289,Q5TKA1,P28066,P25786,P62333,P25789,Q06323,Q13309,P24941	27
Scf skp2 mediated degradation of p27 p21	0.59585794753598	4.016401160938282	5.909363113953958e-05	0.0804909895350943	0.0055941970812098	42	P49720,P25787,P11802,O00487,P48556,P28070,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323,Q13309,P24941	26
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s	0.5292965805590892	3.889094201557368	0.000100619059604	0.1331473350807603	0.0088269582052276	53	P15880,P05198,P56537,P62847,Q13347,P62841,P08865,P62081,P63220,Q9UBQ5,P60842,P62244,P08708,P39019,P62857,Q15056,Q14240,O00303,P62249,P62753,O75821,P60866,P06730,P20042,P62273,O15372,P62854,P62280,P62701,P62277,P62263,P61247	32
Interleukin 1 signaling	0.5323885252820442	3.8771784499015673	0.0001056748517527	0.1393490166866871	0.0088269582052276	50	P49720,P25787,P09429,O00487,P48556,Q13200,O00233,Q9UNM6,P52564,P62191,Q9UL46,P63208,P20618,P51617,P25788,Q15750,P17980,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,Q06323	26
Regulation of expression of slits and robos	0.4681238316739327	3.862875074390795	0.0001120603215081	0.1471184236237355	0.0088403142523075	128	P49720,P25787,P62847,P62841,Q9Y5S9,O00487,P08865,P48556,P62913,Q15369,Q13200,P18621,P62081,O00233,Q07020,P63220,Q9Y3U8,P61313,Q9UNM6,P61513,P62191,Q9UL46,P20618,P08708,P42766,P05388,P62244,P50914,Q15370,P46777,P25788,A7E2V4,P62910,P84098,P32969,P46778,P17980,O75832,P62899,P28072,P28074,P46776,P62495,P62857,P61289,P28066,P25786,P63173,P62333,P61254,P62906,P62273,P62249,P62753,P25789,P30050,P61927,P60866,P62888,P62854,P05386,Q06323,P62829,P26373	64
Regulation of hmox1 expression and activity	0.5289792956322433	3.81464425819593	0.000136379251439	0.176071680494009	0.0101925545812347	48	P49720,P25787,P19784,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,P17980,P67870,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q8TCT9,Q06323,Q13309	25
Dectin 1 mediated noncanonical nf kb signaling	0.5709243985358576	3.7829141677164433	0.0001550028767789	0.1975784174268055	0.0110052042513049	42	P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,P25788,P61081,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q8TBC4,Q06323	21
Regulation of runx3 expression and activity	0.5917951690815767	3.764212262554011	0.0001670749235223	0.2112187234264285	0.0112974472096034	39	P49720,P25787,Q13951,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P20618,P25788,P42771,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	20
Tnfr2 non canonical nf kb pathway	0.5569125724449275	3.7267073285114374	0.0001939975024691	0.2408099804900794	0.0123220797921431	43	P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,P25788,P61081,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q8TBC4,Q06323	21
Hedgehog off state	0.513587195719795	3.718231279556781	0.0002006225527981	0.2479200211819259	0.0123220797921431	53	P49720,P25787,P17612,O00487,P48556,P28070,Q13200,O00233,P04350,Q9BUF5,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,Q9BVA1,Q8NCM8,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323	28
Negative regulation of notch4 signaling	0.5784085169757766	3.708779723773217	0.0002082605035291	0.2560345725560968	0.0123220797921431	40	P49720,P25787,Q9Y6A5,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323	23
Orc1 removal from chromatin	0.5096874529441042	3.690824833969202	0.0002235280341902	0.271993490229312	0.0124095537247829	54	P49720,Q9UBD5,P25787,O00487,P48556,P28070,Q13200,O00233,O43913,Q9UNM6,P62191,Q9UL46,P63208,Q99741,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P25786,O43929,P62333,P25789,Q06323,Q13309,P24941	29
Cellular response to hypoxia	0.5512643096999552	3.671694555010984	0.0002409475505558	0.2897844389932626	0.0124095537247829	43	P49720,P25787,O00487,P48556,Q15369,Q13200,O00233,Q9UNM6,Q9UL46,P20618,Q15370,P25788,Q9Y241,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	21
Apc c mediated degradation of cell cycle proteins	0.4963319430030566	3.646542725068707	0.0002657923015636	0.314409820292781	0.0124095537247829	60	P49720,P25787,Q9UJX4,Q13042,Q9UJX6,O43684,O00487,P48556,P28070,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,O14965,Q96DE5,P17980,O75832,P28072,P28074,P61289,P28066,P25786,Q13257,P62333,P25789,P06493,Q06323,Q13309,P24941	33
G1 s dna damage checkpoints	0.5485245408650337	3.644904614195744	0.0002674909933784	0.316062008502766	0.0124095537247829	43	P49720,P25787,O00487,P48556,P28070,Q13200,O00233,Q9UNM6,O96017,P62191,Q9UL46,P20618,P25788,P42771,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323,P24941	25
Degradation of gli1 by the proteasome	0.5561288481143116	3.641821656401424	0.0002707155993981	0.3191874000043805	0.0124095537247829	42	P49720,P25787,P17612,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,P25788,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	20
Nonsense mediated decay nmd	0.4251578363816518	3.64163424406991	0.0002709127925832	0.3193780622222775	0.0124095537247829	89	P62847,P62841,Q9Y5S9,P08865,P62913,P18621,P30153,P62081,Q07020,P63220,Q9Y3U8,P61313,P61513,P05388,P08708,P42766,P62244,P39019,P50914,P46777,P62910,P84098,P32969,P46778,P62899,P46776,P62495,P62857,P63151,P63173,P61254,P62906,P62273,P62249,P62753,P30050,P60866,P61927,P62888,P62854,P05386,P62829,P62701,Q8ND04,P62280,P26373,P62277,P62263	48
Regulation of pten stability and activity	0.5448577915851006	3.608942225743821	0.0003074480643718	0.3537981595143994	0.0132295833760023	43	P49720,P25787,P19784,O00487,P48556,Q13200,O00233,Q9UNE7,Q9UNM6,Q9UL46,P20618,P25788,P67870,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	21
Resolution of abasic sites ap sites	0.634372633208094	3.573166516823378	0.0003526903233439	0.3940201820311874	0.0136046708977793	28	Q9UGN5,P27695,Q15054,P35244,Q96T60,P39748,P15927,P18887,P78549,P40937,P29372,P18858,Q9NR33	13
Downstream signaling events of b cell receptor bcr	0.5061031881749748	3.570318300530102	0.000356547706134	0.3973315235960833	0.0136046708977793	48	P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,O95999,P25788,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323,Q9UDY8	21
Clec7a dectin 1 signaling	0.4955326156228424	3.564846887466714	0.0003640686578278	0.4037359210801474	0.0136046708977793	56	P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,O95999,P25788,P61081,Q15750,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,Q8TBC4,Q06323,P49427,Q9UDY8	26
Tcr signaling	0.4981628868156919	3.5478153787226767	0.0003884403966445	0.4240258628088555	0.0141432144419294	53	P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,O95999,P25788,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,Q06323,P49427,P50552,Q9UDY8	24
Stabilization of p53	0.5491219637100839	3.5028838520873244	0.0004602501062656	0.4798851344304998	0.015940369534077	41	P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,O96017,Q9UL46,P20618,P25788,P42771,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	20
Regulation of runx2 expression and activity	0.5237613202977403	3.478056174074689	0.0005050640689114	0.5119669512417601	0.0170759756631979	44	P49720,P25787,Q13951,O00487,P48556,Q13200,O00233,Q9UNE7,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323,Q13309	24
Signaling by notch4	0.522915276697698	3.469462605015564	0.0005215006593075	0.5232314362138107	0.017221649679459	44	P49720,P25787,Q9Y6A5,O00487,P48556,Q13200,O00233,Q04721,Q9UNM6,P62191,Q9UL46,P63208,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323	24
Degradation of beta catenin by the destruction complex	0.4928385366299228	3.448905478597986	0.0005628636920209	0.5504424787817873	0.0180956720682906	50	P49720,P25787,O00487,P48556,Q13200,Q13362,O00233,Q9UNM6,Q9UL46,P63208,P20618,P25788,Q13363,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	21
Abc family proteins mediated transport	0.491263564848191	3.443868567511018	0.0005734543965303	0.5571564873096218	0.0180956720682906	51	P49720,P25787,O00487,P48556,P40855,Q13200,O75477,O00233,Q9UNM6,Q9UL46,P20618,P25788,Q9NRK6,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	21
Metabolism of polyamines	0.543948604171274	3.3872582095561303	0.0007059491262852	0.633149827829605	0.0204879828036633	40	P49720,P25787,O00487,P48556,Q13200,P19623,O00233,Q9UNM6,Q9UL46,P20618,P25788,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323,P52788	20
Signaling by robo receptors	0.450703123996138	3.3870770035129643	0.0007064155742579	0.6333929044325891	0.0204879828036633	147	P49720,P25787,P62847,P62841,Q9Y5S9,P17612,O00487,P08865,P48556,P62913,Q15369,Q13200,P18621,P62081,O00233,Q07020,P63220,Q9Y3U8,P61313,Q9UNM6,P61513,P62191,Q9UL46,P20618,P08708,P42766,P05388,P62244,P50914,Q15370,P46777,P25788,P61586,A7E2V4,P62910,P84098,P32969,P46778,P35080,P17980,P07737,O75832,P62899,P28072,P28074,P46776,P62495,P62857,P61289,P28066,P25786,P63173,P62333,P61254,O43639,P62906,P62273,P62249,P25789,P62753,P61927,P30050,P60866,P62888,P62854,P05386,Q06323,P62829,P26373,P50552	70
Cdt1 association with the cdc6 orc origin complex	0.5218764597332112	3.3806821932996827	0.0007230612076294	0.6419627666780096	0.0204879828036633	43	P49720,Q9UBD5,P25787,O00487,P48556,Q13200,O00233,O43913,Q9UNM6,P62191,Q9UL46,Q99741,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,O43929,P62333,P25789,Q06323	24
S phase	0.4143466246409518	3.3670813327242595	0.0007596827972295	0.6601189357000286	0.0204879828036633	105	Q56NI9,P49720,P35244,P25787,P11802,P12004,Q9UBD5,Q9UJX4,Q9UJX6,Q13042,P40937,O00487,Q9BRX5,P48556,P28070,P20248,Q13200,O00233,O43913,Q9UNM6,Q9Y248,P62191,Q9UL46,P63208,P20618,Q99741,Q9NR33,P25788,Q15054,P39748,Q96DE5,P17980,Q9BRT9,O75832,P28072,P28074,P61289,Q5TKA1,P28066,P25786,O43929,P62333,P24941,P25789,P15927,Q06323,P49643,Q13309,P18858	49
Runx1 regulates transcription of genes involved in differentiation of hscs	0.5274858883966057	3.3630918980455777	0.0007707470157456	0.6654211677859521	0.0204879828036633	42	P49720,P25787,Q13951,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	20
C type lectin receptors clrs	0.4661105948713712	3.3304771435828897	0.0008669728094452	0.7081850363702258	0.0208125329287224	62	P49720,P25787,P17612,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,O95999,P25788,P61081,Q15750,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,Q8TBC4,Q06323,P49427,Q9UDY8	27
Auf1 hnrnp d0 binds and destabilizes mrna	0.5238656263587732	3.327325631468891	0.0008768384517652	0.7122481497217912	0.0208125329287224	42	P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200	18
Switching of origins to a post replicative state	0.4621995136523774	3.323953458463469	0.000887510060723	0.7165795701566477	0.0208125329287224	64	P49720,Q9UBD5,P25787,Q9UJX4,Q9UJX6,Q13042,O00487,P48556,P28070,Q13200,O00233,O43913,Q9UNM6,P62191,Q9UL46,P63208,Q99741,P20618,P25788,Q96DE5,P17980,O75832,P28072,P28074,P61289,P28066,P25786,O43929,P62333,P25789,Q06323,Q13309,P24941	33
Abc transporter disorders	0.5303300663879295	3.321902431097815	0.0008940595131352	0.7192055523253951	0.0208125329287224	41	P49720,P25787,O00487,P48556,Q13200,O75477,O00233,Q9UNM6,Q9UL46,P20618,P25788,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	19
Defective cftr causes cystic fibrosis	0.5303300663879295	3.321902431097815	0.0008940595131352	0.7192055523253951	0.0208125329287224	41	P49720,P25787,O00487,P48556,Q13200,O75477,O00233,Q9UNM6,Q9UL46,P20618,P25788,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	19
Degradation of dvl	0.5482692068619686	3.3081768273640777	0.0009390549661789	0.7366008033000078	0.0212585770291392	38	P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200	18
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1	0.4790202480686293	3.3069544649192943	0.0009431622203068	0.7381339941955726	0.0212585770291392	51	P49720,P25787,Q9UJX4,Q13042,Q9UJX6,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P20618,P25788,O14965,Q96DE5,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323,Q13309	27
Cross presentation of soluble exogenous antigens endosomes	0.5522487711117091	3.290639899973367	0.0009995978310204	0.7583195360458261	0.0212646707238057	37	P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200	18
Degradation of axin	0.5522487711117091	3.290639899973367	0.0009995978310204	0.7583195360458261	0.0212646707238057	37	P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200	18
Mapk family signaling cascades	0.4005486053850505	3.2904726490067584	0.0010001922468465	0.7585236493261007	0.0212646707238057	96	P49720,P25787,P36873,P17612,O00487,P48556,Q13557,Q13200,P62140,P31946,Q13362,O00233,Q9UNM6,P62191,Q9UL46,P20618,P25788,Q92796,P17980,O75832,P28072,P28074,P61289,P36404,P28066,P62333,Q99956,P25789,P53041,O75608,P06493,Q06323,P49356,Q16181,Q13555	35
Transcriptional regulation by runx3	0.4895595586740678	3.2890205602311093	0.0010053667922098	0.7602932475676414	0.0212646707238057	46	P49720,P25787,Q13951,O00487,P48556,Q13200,O00233,Q9UNM6,P25440,P62191,Q9UL46,P20618,P25788,P42771,P17980,O75832,P28072,P28074,P61289,Q13485,P28066,P62333,P25789,Q06323	24
Regulation of ras by gaps	0.5327002808417337	3.2800911431774775	0.0010377355595572	0.7710724313269639	0.0213562970227717	40	P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200	18
Transcriptional regulation by runx2	0.4695549139498672	3.2668354269414097	0.0010875688373919	0.7867282597847496	0.0220621107013789	56	P49720,P25787,P11802,Q13951,O00487,P48556,Q13200,O00233,Q9UNE7,Q9UNM6,Q9UL46,P63208,P20618,P25788,P17980,O75832,P28072,P28074,P61289,Q13485,P28066,P62333,P25789,P06493,Q06323	25
Interleukin 1 family signaling	0.4669819613509643	3.2368828032860772	0.0012084302897075	0.8203974029618571	0.023832930713676	56	P49720,P25787,P09429,P43378,O00487,P48556,Q13200,O00233,Q9H3S7,Q9UNM6,P52564,P62191,Q9UL46,P63208,P20618,P51617,P25788,Q15750,P17980,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,Q06323	28
Dna replication pre initiation	0.4520463755864226	3.220568270932421	0.0012793671658295	0.8376278703853118	0.0246573158505549	65	P49720,P35244,P25787,Q9UBD5,O00487,P48556,Q13200,O00233,O43913,Q9UNM6,P62191,Q9UL46,Q99741,P20618,Q9NR33,P25788,P17980,P16104,O75832,P28072,P28074,P61289,P28066,P25786,O43929,P62333,P25789,P15927,Q06323,P24941	30
Mapk6 mapk4 signaling	0.4691522934112728	3.207300583203555	0.0013398691818322	0.8510120732725079	0.0253681898426909	52	P49720,P25787,P17612,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P62333,P25789,P06493,Q06323,Q16181	23
The role of gtse1 in g2 m progression after g2 checkpoint	0.4693935167519212	3.1980942495944817	0.0013833905887765	0.859952645462647	0.0258475610008253	51	P49720,P25787,O00487,P48556,Q13200,O00233,P04350,Q9BUF5,Q9UNM6,P62191,Q9UL46,P20618,P25788,Q9BVA1,P17980,O75832,P28072,P28074,O95067,P61289,P28066,P62333,P25789,P06493,Q06323,Q15691	26
Asymmetric localization of pcp proteins	0.5340991234771234	3.1766579354796662	0.0014898264448253	0.8796235089740031	0.0264585132730551	38	P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200	18
Signaling by hedgehog	0.4585713345783416	3.169067129708558	0.0015292906916128	0.8861934242163043	0.0268097874332137	58	P49720,P25787,P17612,O00487,P48556,P28070,Q13200,O00233,P04350,Q9BUF5,Q9UNM6,P62191,Q9UL46,P63208,P20618,P49407,P25788,Q9BVA1,Q8NCM8,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323	29
Pcp ce pathway	0.4646123451263191	3.143629747133146	0.0016686642304704	0.9066577433319826	0.0288963805764387	51	P49720,P25787,O00487,P48556,P09497,Q13200,O00233,Q9UNM6,Q9UL46,P20618,P25788,P61586,P07737,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	21
Cellular response to chemical stress	0.4205419349384721	3.0909854170498265	0.0019949343130651	0.9413188143065016	0.0337238895780067	76	P49720,P25787,P30048,P19784,O00487,P48556,Q13200,P30041,Q16881,P04179,O00233,Q9UNM6,P30044,Q9UL46,Q86X55,P20618,P63208,P00390,P25788,P67870,O75832,P28072,P28074,P30519,P61289,P28066,P62333,P00403,P25789,Q8TCT9,Q06323	31
Tcf dependent signaling in response to wnt	0.4390817488388667	3.0591012541259346	0.0022200210279392	0.9574014165032974	0.035823066587202	65	P49720,P25787,P19784,O00487,P48556,Q13200,Q13362,O00233,Q9UNM6,Q9UL46,P20618,P25788,Q13363,Q70CQ2,P17980,P67870,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323,Q92993	25
Base excision repair	0.5509162643188543	3.030732174107704	0.0024396154249228	0.9688358384412408	0.0376980926140672	31	Q9UGN5,P27695,Q15054,P12004,P35244,Q96T60,P39748,P15927,P16104,P18887,P78549,P40937,P29372,P18858,Q9NR33	15
Hedgehog on state	0.4869110079568914	3.023642988975439	0.002497509734328	0.9713011972840092	0.0376980926140672	43	P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P20618,P49407,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	21
Pcna dependent long patch base excision repair	0.6366607276776572	3.0206826429151397	0.0025220554917861	0.9722866920127738	0.0376980926140672	19	P27695,Q15054,P35244,P39748,P15927,P40937,P18858,Q9NR33	8
Resolution of ap sites via the multiple nucleotide patch replacement pathway	0.5924874500192717	2.967171602964133	0.0030055316068939	0.9860779497663552	0.0413190346060572	23	Q9UGN5,P27695,Q15054,P35244,P39748,P15927,P40937,P18858,Q9NR33	9
Hedgehog ligand biogenesis	0.5059442345302304	2.963394127483253	0.0030426671018115	0.9867951844634888	0.0413190346060572	39	P25788,P62333,O00233,P49720,P25787,P28074,P25789,Q9UNM6,O75832,Q9UL46,P28072,P20618,O00487,Q06323,P48556,P61289,P28066,Q13200	18
Fc epsilon receptor fceri signaling	0.4310726980502854	2.9019761544014893	0.0037081676538071	0.9948840139951144	0.0465982129947441	62	P49720,P25787,O00487,P48556,P28070,Q13200,O00233,P07948,Q9UNM6,P62191,Q9UL46,P63208,P20618,O95999,P25788,Q15750,P17980,O75832,P28072,P28074,P61289,P28066,P25786,P62333,Q13404,P25789,Q06323,P49427,Q9UDY8	29
Regulation of mrna stability by proteins that bind au rich elements	0.4212077912684603	2.8732536977897087	0.004062677261402	0.9969136074944868	0.0502012001607799	67	P49720,O14818,P25787,O00487,P48556,P28070,Q13200,P31946,Q96B26,Q9Y3B2,O00233,Q9UNM6,P62191,Q9UL46,P20618,P25788,O43242,P39687,Q15717,Q13868,Q9Y2L1,Q16539,P17980,O75832,P28072,P28074,Q9NPD3,P61289,P28066,P25786,P62333,P25789,Q9NQT4,Q01105,Q06323,O00231,Q5RKV6,Q9NQT5	38
Metabolism of water soluble vitamins and cofactors	0.4588956884408518	2.8730272745420327	0.0040655901538659	0.996926399276163	0.0502012001607799	45	P05165,Q9Y4U1,O96007,Q96CD2,P78417,P00374,Q9UKK3,Q9H3L0,Q96EN8,P49914,Q9NZB8,P50747,Q96RQ3,Q9H2D1,P34896,Q8IXQ6,Q8NFF5,P00387	18
Mitotic g2 g2 m phases	0.3760442188575805	2.864152952588388	0.0041812605761155	0.9973937362987854	0.0505825270848159	99	P49720,P25787,P30307,P07437,P17612,O00487,P48556,P62258,P28070,P20248,Q13200,P62140,P30153,O00233,P04350,Q9BUF5,Q9UNM6,P61163,P62191,Q9UL46,P63208,P20618,P61006,P25788,O14965,Q9BVA1,P17980,O75832,P28072,P28074,O95067,Q9H6D7,P61289,Q5TKA1,P63151,P28066,P25786,P62333,P61981,P25789,P06493,Q06323,Q9Y570,P24941,Q15691,P63167	46
Global genome nucleotide excision repair gg ner	0.4630828340973094	2.8435244039970606	0.0044617592409244	0.9982530336075894	0.0525026180918057	44	Q13098,Q9UGN5,Q15054,Q9BT78,P12004,P35244,Q9UBW8,Q9UNS2,Q92905,P15927,P18887,P32780,P40937,P18858,Q9NR33,Q7L5N1	16
Uch proteinases	0.4392061271877827	2.8400399584101224	0.0045107883149297	0.9983710335061876	0.0525026180918057	50	Q9Y5K5,P49720,P25787,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,P20618,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	20
Interconversion of nucleotide di and triphosphates	0.6361921463041156	2.772187088605991	0.0055681024109961	0.9996397816388656	0.0612922901055389	17	Q16881,P32321,Q9H773,P54819,P00390,Q9NRF8,P35754,P33316,P15531	9
Signaling by the b cell receptor bcr	0.4299567968763335	2.76127740987964	0.0057575748570972	0.9997251769974604	0.0613965525144299	53	P49720,P25787,O00487,P48556,Q13200,O00233,P07948,Q9UNM6,P62191,Q9UL46,P63208,P20618,O95999,P25788,P17980,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323,Q9UDY8	24
Metabolism of folate and pterines	0.7842586699856897	2.7602182021025135	0.0057762766848592	0.9997324205237575	0.0613965525144299	9	P00374,P34896,P49914	3
Gap filling dna repair synthesis and ligation in gg ner	0.5941643747394851	2.726699664274995	0.0063971236426358	0.9998897869833644	0.0667934968569336	19	Q15054,P35244,P15927,P18887,P40937,P18858,Q9NR33	7
Dna strand elongation	0.510294579886846	2.651870327023604	0.0080047277737373	0.9999889430504108	0.0794875065643853	30	Q15054,P35244,P39748,Q9Y248,P15927,Q9BRT9,P40937,Q9BRX5,P18858	9
Antigen processing cross presentation	0.4202942430530222	2.635421349878792	0.0084032897767591	0.9999937510117646	0.0817306265958771	52	P49720,P25787,P09429,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P20618,P25788,P60059,P17980,P04439,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323	24
Dual incision in gg ner	0.5240603967314277	2.5268328750282465	0.0115096258479197	0.9999999274109272	0.1089577913603065	25	Q9UGN5,P35251,Q15054,P12004,P35244,P35250,P15927,P32780,Q92889,P18074,P40937,Q9NR33,P19447	13
Signaling by wnt	0.3512894460846851	2.4999166382605513	0.0124222533353257	0.9999999804458324	0.1168185412990899	97	P49720,P25787,P19784,O00487,P48556,P09497,Q96QK1,Q13200,Q13362,O00233,Q9UNM6,Q9UBQ0,Q9UL46,P63208,P20618,P25788,P61586,Q13363,Q9Y3A6,Q70CQ2,P17980,P67870,P07737,O75832,P16104,P28072,P28074,P61289,P28066,P62333,P25789,Q06323,Q92993	33
Transcription coupled nucleotide excision repair tc ner	0.4100044577749367	2.4870816826736304	0.0128795823430936	0.9999999898704148	0.119535992988189	49	Q13098,Q15054,Q9BT78,P12004,P35244,Q9UBW8,Q9UNS2,Q92905,P15927,P62487,P18887,P19387,P32780,P40937,O15514,P18858,Q9NR33,Q7L5N1	18
Polb dependent long patch base excision repair	0.753818108788334	2.371133904106258	0.0177336050801133	0.9999999999907618	0.1564081938742916	7	P18858,Q9UGN5,P27695	3
G2 m checkpoints	0.3415959671267735	2.342429058583802	0.0191586758339497	0.9999999999988244	0.1666339143783252	97	Q9NXR7,Q8N2W9,P49720,P35244,P25787,Q9UBD5,P30307,P40937,O00487,P48556,P62258,Q13200,P31946,O00233,Q9UNM6,O96017,Q9UL46,P20618,Q99741,P38398,P25788,Q9UQ84,P17980,P16104,O75832,P28072,P28074,O95067,P61289,P28066,O43929,P62333,P25789,P15927,P06493,Q06323,P24941,Q92993	38
Signaling by notch	0.3880846713399871	2.3407501039898375	0.0192450436324262	0.9999999999989626	0.1666339143783252	61	P49720,P25787,Q9Y6A5,O00487,P48556,P67809,Q13200,O00233,Q04721,Q9UNM6,P62191,Q9UL46,P63208,P20618,P49407,P25788,P17980,P16104,O75832,P28072,P28074,P61289,P28066,P25786,P62333,P25789,Q06323	27
Cytoprotection by hmox1	0.3802841963700078	2.334073220224821	0.019591888271879	0.9999999999993724	0.1686089778549593	67	P49720,P25787,P19784,O00487,P48556,Q13200,O00233,Q9UNM6,Q9UL46,Q86X55,P20618,P63208,P25788,P17980,P67870,O75832,P28072,P28074,P30519,P61289,P28066,P62333,P00403,P25789,Q8TCT9,Q06323	26
Cyclin d associated events in g1	0.6282193207687119	2.3105018691356185	0.02086038517634	0.9999999999999002	0.1743317835562264	13	P42771,P30153,P11802,P07948,P06400,P63208,Q13309,P24941,P63151	9
Dna damage recognition in gg ner	0.5468777485569203	2.2744701852611415	0.0229377317381151	0.9999999999999952	0.1819641288721987	18	Q9UGN5,Q9BT78,Q9UBW8,Q9UNS2,Q92905,Q7L5N1	6
Mismatch repair	0.6186484971072445	2.252814972708879	0.0242708177360637	0.9999999999999992	0.1914697843622808	13	Q15054,Q9UQ84,P35244,P15927,P18858	5
Lagging strand synthesis	0.5061950932619983	2.233399240662971	0.0255226282199256	1.0	0.1988674749833253	21	Q15054,P12004,P35244,P39748,P35250,P15927,P49643,P40937,P18858	9
Tgf beta receptor signaling activates smads	0.6303327918557673	2.2333661552708364	0.0255248081686803	1.0	0.1988674749833253	12	P62140,P61081,P62136,Q9Y5K5,Q9UNE7,P36873,Q9Y3F4	7
Downregulation of tgf beta receptor signaling	0.6821855362517186	2.231792266151636	0.025628695719682	1.0	0.1988674749833253	9	P62140,P62136,Q9Y5K5,Q9UNE7,P36873	5
Copi independent golgi to er retrograde traffic	0.4596345878146823	2.180830973982867	0.0291959206889562	1.0	0.218201091464831	29	Q96FJ2,P47755,Q13561,Q9BVA1,Q9BUF5,Q8TD16,P04350,Q15042,P68371,Q9NZ32,P61163,P68402,P52907,Q9Y6G9,P63167,Q9UJW0,O75935	17
Activation of ampk downstream of nmdars	0.6860485281015707	2.1386237911937744	0.0324661491071518	1.0	0.2388701126018425	8	P04350,Q9BUF5,Q13131	3
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex	0.6247001222145149	2.11926639948901	0.0340679595780324	1.0	0.2493634154680724	11	P31946,Q9Y3B8,P61981,P30307,O96017,P06493,P14635,P62258	8
Antigen processing ubiquitination proteasome degradation	0.3313421888825048	2.111625684812255	0.0347185677299692	1.0	0.2517842048116725	101	Q9BSL1,Q5GLZ8,Q9Y508,P49720,P25787,O95352,Q13042,O00487,P48556,Q15369,Q13200,O00233,Q9UNE7,Q9UNM6,Q9UL46,P63208,P20618,Q15370,P25788,P61081,Q9H2C0,P17980,O75832,P28072,P28074,P61289,P28066,P62333,Q05086,Q13404,P25789,Q8TDB6,Q8TBC4,Q06323,Q13309,P49427,O94822,Q63HN8	38
Triglyceride metabolism	0.6411086369686292	2.1076144221831616	0.0350643550542746	1.0	0.2517842048116725	10	P62140,Q01469,P62136,P36873,P17612	5
Rho gtpases activate pkns	0.491689362069713	2.0927688041438333	0.0363697978658228	1.0	0.2548456615282485	20	P62140,P31946,P61586,P30307,P16104,Q7Z406,P62258,P60660	8
Intraflagellar transport	0.5904263935706834	2.080734937434794	0.0374581743300406	1.0	0.2548456615282485	13	Q96FJ2,Q9BVA1,A0AVF1,Q9BUF5,P04350,Q9BW83,Q96EX3,P63167	8
Dna damage reversal	0.7490252772524806	2.0524014936621997	0.0401306594971058	1.0	0.2675377299807054	6	P16455,Q8N9N2	2
Detoxification of reactive oxygen species	0.6434689579411556	2.0231389779865774	0.0430588209011408	1.0	0.2754212868451353	9	Q16881,P04179,P30048,P30044,P00390	5
Triglyceride catabolism	0.6427324241865701	2.0191271801069957	0.0434740025046758	1.0	0.2762934465201729	9	P62140,Q01469,P62136,P36873,P17612	5
Metabolism of nucleotides	0.3779465589458702	2.0180666699822276	0.0435843183243089	1.0	0.2762934465201729	46	Q9UKK9,P04183,Q9P2T1,Q9NRF8,P00492,Q16881,O43598,P49915,P49902,P00390,P07741,Q9H0P0,P20839,Q96DE0,P00491,Q9BY32,P33316,P55263,Q9H773,P54819,P35754,P32321,P15531	23
Metabolism of cofactors	0.7410784027770565	2.015327751275136	0.0438703190291782	1.0	0.2768704578730361	6	P00374	1
Maturation of sars cov 2 nucleoprotein	0.6816649221342623	2.01029317663454	0.0444001686379107	1.0	0.2777896303453905	7	Q96SB4,Q9UKK3,P49840,Q8IXQ6,Q99873	5
Regulation of tp53 activity through phosphorylation	0.4007249841059234	1.98561596019996	0.0470759829086495	1.0	0.284459130767159	41	Q96S44,O14965,Q13131,P40937,P35244,Q9UQ84,P54619,Q16539,P15927,P67870,O96017,P19784,P38398,P24941,Q92993	15
Nucleotide salvage	0.6560288134535831	1.9812856942744417	0.0475592437642116	1.0	0.2846547248646149	8	P55263,P04183,Q9P2T1,P00491,P07741	5
Processive synthesis on the lagging strand	0.5452208845577625	1.9807977943579045	0.0476139542712488	1.0	0.2846547248646149	15	Q15054,P35244,P39748,P15927,P18858	5
Mrna decay by 3 to 5 exoribonuclease	0.5313331092964031	1.9712392256441291	0.048696519166852	1.0	0.2857399058550821	16	Q96B26,Q9Y3B2,Q9Y450,Q9GZS3,Q96C86,Q969T7,Q13868,Q9Y2L1,Q9NPD3,Q5RKV6,Q9NQT5	11
Translesion synthesis by polk	0.6156615029467355	1.964641105549118	0.0494557908515087	1.0	0.2890009177330964	10	P12004,P35244,P35250,P15927,P40937	5
Gene and protein expression by jak stat signaling after interleukin 12 stimulation	0.4560173167102337	1.924975456516215	0.0542324288223607	1.0	0.313048979381107	24	P52597,P04179,P05388,Q99439,P14174,Q9UL46,Q00169,P23528,Q13126	9
Apoptotic factor mediated response	0.6244841498496849	1.9192432686468397	0.0549535539715273	1.0	0.3147772411294166	9	Q96GX9,Q07021,P42771,Q16611	4
Intrinsic pathway for apoptosis	0.4593117412180822	1.9190723344258485	0.0549751801409121	1.0	0.3147772411294166	23	Q96FJ2,P31946,P42771,P61981,Q96GX9,Q07021,Q16611,P30419,P62258,P63167	10
Metabolism of amino acids and derivatives	0.3879805842155066	1.8960455136673928	0.0579540264346891	1.0	0.325812046404119	199	P62841,Q13126,P63220,Q9Y3U8,P61513,Q9UL46,Q14353,P00390,Q96I15,P16930,Q96GX9,Q9BV57,O75832,P34896,P28066,O43324,P12277,P61927,P62888,P62854,Q06323,P52788,P26373,P49720,P25787,P62847,O00487,O43708,Q16881,P78330,P21953,Q07020,P61313,P20618,P08708,P32969,P62899,P25325,P28072,P28074,P61289,P62333,P61254,P17174,P48556,P62913,Q13200,Q12904,P19623,P62081,O00233,Q9UNM6,P42766,P46778,P17980,P46776,P62857,P63173,Q99714,P62906,P62273,P62249,P62753,P25789,P05386,P08865,P18621,P62191,P57772,P05388,P62244,Q6NVY1,P50914,P46777,P25788,P62910,P84098,P61457,P25786,P30050,P60866,Q96RQ3,P62829	83
Cooperation of prefoldin and tric cct in actin and tubulin folding	0.5076324745650956	1.895323089089786	0.0580496110846775	1.0	0.325812046404119	17	Q9NQP4,P04350,Q9BUF5,Q9UHV9	4
Ub specific processing proteases	0.3148197754118851	1.8932390564433448	0.0583260856399672	1.0	0.3260749669635962	88	Q9NZL9,P49720,Q9UPT9,P25787,Q14318,Q9Y5T5,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P20618,P25788,Q9Y277,Q96FW1,Q15750,Q70CQ2,P17980,O75832,P28072,P28074,O60493,P61289,Q13485,P28066,P62333,P25789,Q06323,P54578,Q13309	32
Transcriptional regulation by runx1	0.3322589450498843	1.8607560250329152	0.0627786381259092	1.0	0.3436294797953941	77	P49720,P25787,Q15723,Q13951,P19784,O00487,P48556,Q99873,Q13200,O00233,Q9UNM6,Q9UL46,P20618,P25788,Q16625,Q92925,P17980,Q12824,P67870,O75832,P28072,P28074,P61289,P28066,O00257,P62333,P25789,Q06323	28
Ephrin signaling	0.63314904409658	1.8597699981509128	0.0629180737653538	1.0	0.3436294797953941	8	O00560,Q9Y2X7	2
Termination of translesion dna synthesis	0.4599673063570129	1.843521853314103	0.0652528540326684	1.0	0.3539940760982745	20	Q15054,P35244,P15927,Q15004,P40937,Q9NR33	6
Activation of nmda receptors and postsynaptic events	0.4218111135342527	1.835408900554932	0.0664451259229461	1.0	0.357394237918877	29	P10644,Q92796,Q9BVA1,Q13131,P04350,Q9BUF5,P54619,Q13555,P17612,Q9Y2X7,Q15418,Q13557	12
Pten regulation	0.3390797416609811	1.8199395776021312	0.0687682069160893	1.0	0.3671084730107024	70	P49720,P25787,P19784,O00487,P48556,O00233,Q9UNE7,Q9UNM6,Q9UL46,P20618,P25788,P67870,O75832,P28072,P28074,P61289,P28066,P62333,O00257,P25789,Q06323	21
Unwinding of dna	0.6043364241429848	1.807911994481722	0.0706201986616994	1.0	0.3741816496254224	9	Q9Y248,Q9BRX5	2
Metabolism of vitamins and cofactors	0.3509280892100462	1.797963302400903	0.0721828234126009	1.0	0.3776558810648339	55	Q9Y4U1,O96007,Q96CD2,P00374,Q5T2R2,Q96EN8,P49914,P50747,Q96RQ3,Q86YH6,P34896,Q9H2D1,Q8NFF5	13
Transport to the golgi and subsequent modification	0.3196380791356897	1.766794808403836	0.0772625984905954	1.0	0.394650682937574	81	P54920,P47755,Q16706,P56962,Q9Y296,P83436,P33908,P04350,Q9UP83,P61923,Q9BUF5,O14579,Q9H0V9,P61163,O15027,P63167,P18085	17
Deadenylation dependent mrna decay	0.3663066187734638	1.7565629380205932	0.0789923348324284	1.0	0.4000112849323941	44	Q9Y450,O75175,Q96B26,Q9Y3B2,Q9GZS3,Q9UK45,Q86TB9,P60842,Q9UIV1,Q5TAX3,Q969T7,Q13868,Q9Y2L1,Q9Y333,Q9NPD3,Q14240,Q9H074,Q96F86,Q96C86,P06730,Q8IZD4,Q5RKV6,Q9NQT5	23
Gamma carboxylation hypusine formation and arylsulfatase activation	0.5508242651056966	1.755846392451346	0.0791146404682872	1.0	0.4000112849323941	12	Q9BU89,P49366,P63241,Q9HA64	4
Phenylalanine and tyrosine metabolism	0.7971017755937965	1.7555974806369226	0.0791571627225371	1.0	0.4000112849323941	4	P61457,P16930	2
Purine salvage	0.6312665186666139	1.7504914886533989	0.0800335415462707	1.0	0.4015817279000157	7	P07741,P00491,P55263,Q9P2T1	4
Intra golgi traffic	0.5371556736499632	1.748379115322575	0.0803984018271632	1.0	0.4019920091358164	13	P54920,Q16706,P33908,P83436	4
Rho gtpases activate rocks	0.5728027364820181	1.719639053500107	0.0854980726258425	1.0	0.416446009880164	10	P62140,Q7Z406,P61586,P60660	4
Methionine salvage pathway	0.7292374931962761	1.715052721835299	0.0863355612569232	1.0	0.4169948877035067	5	Q96GX9,Q9BV57,Q13126	3
Nucleotide excision repair	0.3412280369720575	1.705206500640212	0.0881559180543893	1.0	0.4243437411431624	59	P12004,P35244,Q9UBW8,Q9UNS2,P62487,P19387,P40937,O15514,Q9BT78,Q92905,Q9NR33,Q9UGN5,Q15054,P18887,P32780,Q7L5N1,Q13098,P15927,P18858	19
Copi mediated anterograde transport	0.3437632611015968	1.699218120329557	0.0892780934111252	1.0	0.4282935562290468	54	Q96FJ2,Q9Y3B3,Q9UP83,P54920,P62820,P04350,Q9BUF5,P61923,P61163,P84085,P52907,P48444,P47755,Q9BVA1,P83436,Q8N6T3,P18085,O14579,P63167	19
Interleukin 12 signaling	0.4197418512000379	1.6855440162023023	0.0918836600333175	1.0	0.4378348900916471	26	P52597,P04179,P05388,Q99439,P14174,Q9UL46,Q00169,P23528,Q13126	9
Signaling by interleukins	0.3191597561088484	1.6453350588021065	0.0999007337483224	1.0	0.4503461648337074	119	P49720,P09429,P25787,P43378,P17612,Q00169,O00487,P48556,Q15418,Q13126,P51452,Q13200,P52597,P04179,P14174,O00233,P78417,Q9H3S7,P07948,Q9UNM6,P52564,P62191,Q9UL46,P63208,P20618,P05388,P52907,P51617,P23528,P25788,Q99439,Q15750,Q16539,P17980,O75832,P28072,P28074,P61289,P28066,P62333,Q13404,P25789,P04083,Q06323	44
Tbc rabgaps	0.4342897078998793	1.6384385295167507	0.1013302472367509	1.0	0.4539083630163609	20	P60520,Q15276,P62330,Q15286,Q92930,Q9UJ41,P61006	7
Recycling of eif2 gdp	0.5913098756194555	1.6343274365095632	0.1021901156811528	1.0	0.4548901701167306	8	P05198,P49770,P20042,Q9NR50,Q14232,Q13144	6
Beta catenin independent wnt signaling	0.3316016709517012	1.629528410246263	0.1032012056290716	1.0	0.4565286977983854	64	P49720,P25787,O00487,P48556,P09497,O00233,Q9UNM6,Q9UL46,P20618,P25788,P61586,P07737,O75832,P28072,P28074,P61289,P28066,P62333,P25789,Q06323	20
Cilium assembly	0.3302728446561139	1.6236751804484004	0.1044451507863712	1.0	0.460596627691451	65	A0AVF1,P36405,P04350,Q8IYI6,Q9BUF5,P61163,Q96EX3,Q9BW83,P06493,P07437,P17612,Q15051,Q9H6D7,P62258,P63167,P18085	16
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand	0.391466866831413	1.616633947490257	0.1059573195526022	1.0	0.4635219032945461	33	Q96FJ2,P54652,P68371,Q15185,P04350,Q9BUF5,P61163,Q13451,P52907,Q9UJW0,O75935,P47755,Q9BVA1,Q9NZ32,O60884,Q13561,P31689,Q9Y6G9,P63167,P31948	20
Translesion synthesis by polh	0.5156798270456658	1.6119742735641542	0.1069675381013885	1.0	0.4659322211778276	13	Q8TAT6,P12004,P35244,P35250,P15927,P40937	6
Wnt ligand biogenesis and trafficking	0.7601123595505661	1.5994467698487111	0.1097213672273114	1.0	0.4735694269385477	4	Q9UBQ0,Q9Y3A6,Q96QK1	3
Glutathione conjugation	0.4863437156103418	1.5844672359032872	0.113087431898009	1.0	0.482493414271069	15	P28161,O75223,P78417,Q8WUX2,P21266,P10768,Q96KP4,O43708	8
Rab geranylgeranylation	0.4275484230295426	1.5842004827322422	0.1131481034875112	1.0	0.482493414271069	20	P62820,Q92696,Q15286,P61026,P51148,Q92930,Q969Q5,P61006	8
Trna modification in the nucleus and cytosol	0.4512656421209336	1.574313645738903	0.1154149565889675	1.0	0.4899051825634767	18	Q96S44,Q96FX7,Q9NPF4,Q9UET6,Q9UJA5,Q9UI30,Q96PZ0,Q9UBP6	8
Synthesis of dolichyl phosphate	0.9090398652442484	1.5488285046761243	0.1214229513463689	1.0	0.5012500788665774	2	P53602	1
Molybdenum cofactor biosynthesis	0.6432243091242779	1.5488008691191468	0.1214295965704947	1.0	0.5012500788665774	6	O95396,Q96EN8,O96007,Q9NZB8	4
Recognition of dna damage by pcna containing replication complex	0.4337842033791429	1.533388709343982	0.1251801089850679	1.0	0.5040839641929865	19	Q15054,P35244,P15927,P40937,Q9NR33	5
Signaling by mras complex mutants	0.6873019553588897	1.5257549165136584	0.1270709122577107	1.0	0.5040839641929865	5	P62140,P36873	2
Synaptic adhesion like molecules	0.5704510968246421	1.5206105877401976	0.1283575882641172	1.0	0.5052641204730784	8	Q92796	1
Hdr through homologous recombination hrr	0.3867108046002208	1.5200316732122965	0.1285030154240516	1.0	0.5052641204730784	30	Q15054,P35244,Q9UQ84,Q96B01,Q92993,P15927,P40937,P38398,Q9NR33	9
Branched chain amino acid catabolism	0.476318360708375	1.5160037335379564	0.1295184083466201	1.0	0.5052641204730784	15	Q6NVY1,Q99714,P21953	3
Sema4d induced cell migration and growth cone collapse	0.5846388596350715	1.505393147594844	0.1322230297741882	1.0	0.5144019240530062	7	P61586,P60660	2
Mtor signalling	0.4726348620234311	1.4907991357329728	0.1360142387635829	1.0	0.5262676268236726	15	P62753,P54619,Q13131	3
Regulation of plk1 activity at g2 m transition	0.362002025258178	1.4827561439970862	0.1381392118888758	1.0	0.5270313881075145	39	P62140,P04350,P61163,P06493,P07437,P17612,P63208,Q9H6D7,P62258,P63167,P61006	11
Tp53 regulates transcription of genes involved in g2 cell cycle arrest	0.5462358604910232	1.4815724843782747	0.1384540849194722	1.0	0.5270313881075145	9	O14965,P12004,P30307,P06493,Q99873	5
Long term potentiation	0.6278690069998174	1.4742139750444212	0.1404239882994706	1.0	0.5289179400139215	6	Q13555,Q92796,Q13557	3
Signaling by tgf beta receptor complex	0.4020758682107208	1.4663386431450645	0.14255605281555	1.0	0.5353353020262362	24	P62140,P08047,P61081,P61586,P62136,Q9Y5K5,Q9UNE7,P36873,Q9UPN9,Q9Y3F4	10
Translesion synthesis by y family dna polymerases bypasses lesions on dna template	0.405071193509275	1.4651435900422929	0.1428817461041855	1.0	0.5353353020262362	23	Q8TAT6,Q15054,P12004,P35244,P35250,P15927,Q15004,P40937,Q9NR33	9
Autophagy	0.3229005993413006	1.455968936037029	0.1454012071444099	1.0	0.5428914081900633	58	Q13131,P04350,Q9BUF5,Q13404,P13473,Q9H9H4,O95352,P54619,P67870,P19784,P63167	11
Wnt mediated activation of dvl	0.8860190903986551	1.455022194255771	0.1456631172678972	1.0	0.5428914081900633	2	P67870	1
Eph ephrin signaling	0.367029271457545	1.443121632245841	0.148986210544805	1.0	0.5479493639298747	36	P61586,O00401,O15144,O43639,Q7Z406,O15145,O00560,Q9Y2X7,P23528,P60660	10
Homology directed repair	0.3237645466827625	1.4337785477256708	0.1516354686790419	1.0	0.5508461890874654	52	Q9NXR7,Q9UGN5,Q15054,Q8N2W9,P35244,Q9UQ84,Q96B01,P24941,P38398,P60510,Q9NR33	11
Regulation of tp53 expression and degradation	0.4638152181565574	1.4303612793944231	0.1526133553816695	1.0	0.5518752372725484	15	P24941,O96017,P42771	3
Formyl peptide receptors bind formyl peptides and many other ligands	0.8795620437956245	1.428704459310835	0.1530891955829909	1.0	0.5518752372725484	2	P04083	1
Rho gtpases activate paks	0.4975329776988204	1.4258791278915508	0.1539032351830487	1.0	0.5518752372725484	12	P62140,P35240,P60660	3
Unblocking of nmda receptors glutamate binding and activation	0.6555938373236119	1.3814413448589382	0.1671433009043705	1.0	0.5745669444272182	5	Q13555,Q92796,Q13557	3
Darpp 32 events	0.5142059018553147	1.3779436396614844	0.1682206898994984	1.0	0.5745669444272182	10	P10644,P62136,P17612	3
Displacement of dna glycosylase by apex1	0.8767200224656084	1.3740448633938007	0.1694277549673783	1.0	0.5745669444272182	3	P27695,P78549	2
Processive synthesis on the c strand of the telomere	0.4778710804585909	1.369504125607404	0.1708417460767206	1.0	0.5762358181210055	13	Q15054,P35244,P39748,P15927,P18858	5
Signaling by tgfb family members	0.3870881974030213	1.365249876512115	0.1721745269510224	1.0	0.5771574508610435	25	P62140,P08047,P61081,P61586,P62136,Q9Y5K5,Q9UNE7,P36873,Q9UPN9,Q9Y3F4	10
Metabolism of nitric oxide nos3 activation and regulation	0.5416217757002726	1.362410873532886	0.1730682540732115	1.0	0.5771574508610435	8	O95865,O75608,O94760	3
Endosomal sorting complex required for transport escrt	0.5102827608853	1.3548902296829144	0.1754525329786067	1.0	0.5776564800225684	10	Q9NP79,Q9H9H4	2
Raf independent mapk1 3 activation	0.6033732067995738	1.354759587263623	0.1754941661545843	1.0	0.5776564800225684	6	Q99956	1
Activation of atr in response to replication stress	0.389002650833339	1.3539957111045895	0.1757377460350349	1.0	0.5776564800225684	24	O43929,P35244,Q9UBD5,Q99741,P30307,P15927,P40937,P24941	8
Raf activation	0.4522863361990391	1.3512210100732014	0.1766246462766765	1.0	0.5778963080941951	15	P62140,P31946,Q13362,P36873,Q13557,Q13555	6
Ubiquinol biosynthesis	0.860190903986531	1.3497889363950777	0.1770836946870817	1.0	0.5780663136911635	2	Q5T2R2	1
Methylation	0.5223289171010199	1.3456519538363048	0.1784147880767195	1.0	0.5788169357402428	9	P51580,Q9NZL9,P78417,Q9HBK9,Q9UI30	5
Early phase of hiv life cycle	0.5189804249063841	1.3265738646780278	0.1846496860400988	1.0	0.5932184483641183	9	P18858,P39748,P17096	3
Ptk6 regulates cell cycle	0.8534531162268424	1.32236744810197	0.1860458229314576	1.0	0.5950114156816889	2	P24941	1
Mrna decay by 5 to 3 exoribonuclease	0.489042755989398	1.3115162089770247	0.1896834211681526	1.0	0.6009985318004357	11	Q86TB9	1
Enos activation	0.640260296254921	1.3114485412247017	0.1897062682950481	1.0	0.6009985318004357	5	O75608,O95865	2
Fanconi anemia pathway	0.5160229379110335	1.3097186628234088	0.1902910276740304	1.0	0.6009985318004357	9	P15927,P35244,O15360,Q9BXW9	4
Negative regulation of nmda receptor mediated neuronal transmission	0.5936083523866319	1.3070374274040115	0.1912000005467979	1.0	0.602004436311426	6	Q13555,Q92796,Q13557	3
Receptor mediated mitophagy	0.6382561003499752	1.30229550953669	0.1928153861236641	1.0	0.6048069355224711	5	P67870	1
Interleukin 12 family signaling	0.3642545831869315	1.2975022859854533	0.1944584190770877	1.0	0.6051556589573605	29	P52597,P04179,P05388,Q99439,P14174,Q9UL46,Q00169,Q13126	8
Vxpx cargo targeting to cilium	0.5001997101781289	1.295597138876592	0.1951143153651813	1.0	0.6051556589573605	10	Q8IYI6,P18085,P61006	3
Cytosolic iron sulfur cluster assembly	0.5132934856792223	1.2941599591626889	0.1956101742686116	1.0	0.6051556589573605	9	O76071,Q9Y5Y2,P53384	3
Inositol phosphate metabolism	0.5259531284093402	1.2761360764226397	0.2019074206192179	1.0	0.6182754328477855	8	Q13572,Q96PE3	2
Butyrate response factor 1 brf1 binds and destabilizes mrna	0.4627770778956658	1.2722760756078395	0.2032750459039161	1.0	0.6207539036205609	13	P31946,Q96B26,Q9Y3B2,Q13868,Q9Y2L1,Q9NPD3,Q5RKV6,Q9NQT5	8
Nicotinate metabolism	0.5860033726812873	1.2698522191831616	0.2041372757512389	1.0	0.6215014319801029	6	Q9BQG2,Q4G0N4,Q9UKK3,P43490,Q8IXQ6	5
Activation of bad and translocation to mitochondria	0.5246811285999889	1.2691286337931924	0.2043951892497943	1.0	0.6215014319801029	8	P31946,P62258,P61981,Q9Y3B8	4
Rrna processing in the mitochondrion	0.629074871244451	1.260362061669864	0.207538781064029	1.0	0.629711686134447	5	Q8WVM0,Q99714	2
Intracellular signaling by second messengers	0.2787815645509833	1.2534471727518328	0.2100430130502624	1.0	0.6337861769022982	100	P49720,P25787,P17612,P19784,O00487,P48556,P28070,Q13557,Q13200,P19174,P10644,Q13362,P30153,O00233,Q9UNE7,Q9UNM6,P62191,Q9UL46,P20618,P51617,P25788,P17980,P67870,O75832,P28072,P28074,P61289,P28066,P25786,O00257,P62333,P25789,Q06323,P49840,Q13555,Q8TBX8	36
Activation of the pre replicative complex	0.3799911701938391	1.2529590052096595	0.210220626282382	1.0	0.6337861769022982	23	O43929,O43913,P35244,Q9UBD5,P15927,Q99741,P24941,Q9NR33	8
Apoptosis	0.2736672841012806	1.2296441845765491	0.218830376509016	1.0	0.6514447267144713	96	Q96FJ2,P49720,P09429,P25787,O00487,P48556,P62258,Q13200,P31946,P26583,O00233,Q9UNM6,Q07021,P62191,Q9UL46,P20618,P25788,P42771,Q16625,Q96GX9,P17980,O75832,P28072,P28074,P30419,P61289,P28066,P62333,P55212,P61981,P25789,Q06323,P63167,Q16611,Q9UJU6	35
Tristetraprolin ttp zfp36 binds and destabilizes mrna	0.4451464944957859	1.2263493001244117	0.2200672563821297	1.0	0.6523914489825141	14	P31946,Q96B26,Q9Y3B2,Q13868,Q9Y2L1,Q9NPD3,Q5RKV6,Q9NQT5	8
Anchoring of the basal body to the plasma membrane	0.3453613197569373	1.2216137244684693	0.2218537360822441	1.0	0.6537720211256189	36	P04350,P61163,P06493,P07437,P17612,Q15051,Q9H6D7,P62258,P63167	9
Epha mediated growth cone collapse	0.4875961298783483	1.2214540191680496	0.2219141649172875	1.0	0.6537720211256189	10	P61586,P60660	2
Assembly and cell surface presentation of nmda receptors	0.472104477508665	1.208551878357369	0.2268350534960257	1.0	0.6587030183320175	11	Q92796,Q9BVA1,Q9BUF5,P04350,Q13557,Q13555	6
Rho gtpases activate cit	0.4830611579935682	1.1947862610919715	0.2321705495264852	1.0	0.6676469537647531	10	P62140,P61586,P60660	3
Polymerase switching	0.4294740552509559	1.194542280486144	0.2322659120843577	1.0	0.6676469537647531	15	Q15054,P12004,P35250,P49643,P40937	5
Foxo mediated transcription	0.4471174463177653	1.1714527879505163	0.2414168244207311	1.0	0.6727547801790511	13	P31946,P04179,Q96EB6,Q13485	4
Nervous system development	0.3572080432010399	1.169234581330478	0.2423091319818828	1.0	0.6727547801790511	230	P62841,Q00169,Q7Z406,P60660,Q9Y3U8,P63220,P61513,Q9UL46,P23528,Q92796,O75832,P28066,O00401,O15144,P61927,P62888,P62854,Q06323,P26373,P49720,P25787,P62847,O00487,Q9Y2X7,P09497,Q15369,Q07020,P04350,P61313,P20618,P08708,O00560,A7E2V4,P32969,Q16539,O75962,P67870,P62899,O15145,P28072,P28074,P61289,P62333,P61254,O43639,O95372,Q9Y5S9,P48556,P62913,Q15418,Q13200,P62081,P61160,O00233,Q9UNM6,P42766,Q15370,P46778,P35080,P17980,P07737,P46776,P62495,P62857,P63173,P62906,P62273,P62249,P62753,P25789,P05386,P50552,P17612,P19784,P08865,P18621,Q9BUF5,P07948,P62191,P05388,P62244,P50914,P46777,P25788,P61586,Q9BVA1,P62910,P84098,P25786,P30050,P26038,P60866,P62829,P62280	94
G1 s specific transcription	0.4464962080399659	1.1674577377652309	0.243025565970238	1.0	0.6727547801790511	13	P12004,P00374,P04183,P06493,Q99741,Q5TKA1	6
Circadian clock	0.4558067206689399	1.1651030457207396	0.2439772841732366	1.0	0.6727547801790511	12	P62140,Q96EB6,P36873,P63208	4
Runx1 regulates transcription of genes involved in bcr signaling	0.8144300954520001	1.164160416310142	0.2443590083668838	1.0	0.6727547801790511	2	Q15723	1
Tyrosine catabolism	0.8135878719820404	1.1607623804687657	0.2457385456432832	1.0	0.6727547801790511	2	P16930	1
Formation of tc ner pre incision complex	0.353508990050132	1.160397179851285	0.2458871344457236	1.0	0.6727547801790511	28	Q13098,Q9BT78,Q9UBW8,Q9UNS2,Q92905,P62487,P32780,P19387,O15514,Q7L5N1	10
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects	0.6567415730337235	1.158140928147604	0.2468065300733652	1.0	0.6739716782772667	4	P24941,P11802,P06400	3
Dna repair	0.299759330853276	1.1563948130403754	0.2475197022610946	1.0	0.6746218372567263	132	Q9NXR7,Q8N2W9,P35244,Q9UBW8,Q9UNS2,O00213,P62487,Q15004,P19387,P78549,P40937,O15514,Q04323,Q9NY27,Q9BT78,Q96T60,Q92905,O96017,P38398,P29372,P16455,Q9NR33,Q9UGN5,P27695,Q15054,Q9UQ84,Q96B01,P39748,P18887,Q9BXW9,P32780,P60510,Q6P6C2,Q7L5N1,P24941,P53041,Q8N9N2,P15927,P18858,Q92993	40
Small interfering rna sirna biogenesis	0.6557590634697132	1.153947989118834	0.2485214929352852	1.0	0.6760546359542242	4	Q15631	1
Rab gefs exchange gtp for gdp on rabs	0.3525794491121061	1.1518807133887476	0.2493700946066885	1.0	0.6761002151632157	28	Q9Y2L5,Q9Y296,Q15286,P61026,Q92930,P62258,P61006	7
Nod1 2 signaling pathway	0.4620820093360805	1.1476964106362648	0.2510939134670518	1.0	0.6767088192426616	11	Q13404,Q15750,P52564,Q16539,P42575	5
Synthesis of substrates in n glycan biosythesis	0.373298160483841	1.145268711129051	0.2520978629432169	1.0	0.6767088192426616	20	O95394,Q9Y5P6,Q13630,Q86YN1,P53602,P10619,Q9UJ70,Q8NFW8,Q96IJ6	9
Rhobtb2 gtpase cycle	0.3726971422738001	1.1404182996416368	0.2541120725275891	1.0	0.6808285716776917	20	Q15208,Q8IYB3	2
Ketone body metabolism	0.6004161135297348	1.1296146712532409	0.2586386262292781	1.0	0.6875559264703384	5	P55809,Q9BUT1	2
Negative regulation of mapk pathway	0.4393247263829396	1.1213832130769965	0.2621247785571396	1.0	0.6892910843539599	13	P31946,Q99956,P53041	3
Activated tak1 mediates p38 mapk activation	0.554397539503804	1.11543698048392	0.2646632098423669	1.0	0.6922968152097245	6	Q13404,Q16539,Q15750,P52564	4
Telomere c strand lagging strand synthesis	0.361174188892969	1.1152801197540758	0.264730401872451	1.0	0.6922968152097245	24	Q15054,P35244,P39748,P15927,P40937,P18858	6
Organelle biogenesis and maintenance	0.2679681009343721	1.1058626686574182	0.2687859650662916	1.0	0.7008130235185449	98	A0AVF1,P54619,P07437,P17612,P62258,P04179,P04350,Q8IYI6,Q9BUF5,P61163,Q96EX3,P61006,Q06546,Q9BW83,Q9H6D7,P18085,P48735,Q5XKP0,P06493,Q15051,P36405,P63167	22
Homologous dna pairing and strand exchange	0.3639579595204065	1.083343639287718	0.2786559221283982	1.0	0.7053322806102058	21	Q9UQ84,P35244,Q96B01,P15927,P38398,Q92993	6
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1	0.589392133126321	1.0794815593263754	0.2803731100715798	1.0	0.705871479783281	5	P06493,P20248,Q5TKA1	3
Ikk complex recruitment mediated by rip1	0.6370004460615017	1.074063896195805	0.2827940446486114	1.0	0.7064291248030504	4	Q13404,Q6SZW1	2
Nicotinamide salvaging	0.5858387187412099	1.063353014366114	0.2876218918952971	1.0	0.7090678584918781	5	Q8IXQ6,Q9BQG2,Q9UKK3,P43490	4
Regulation of bach1 activity	0.6305306863516831	1.0466073550326949	0.2952807082790052	1.0	0.7216843472567769	4	Q13309,P63208	2
Sumoylation of dna methylation proteins	0.6275280898876388	1.0338854757707887	0.301189705761955	1.0	0.7300495327268103	4	O00257,P26358,Q99496	3
Rap1 signalling	0.6269320557881974	1.0313617742429206	0.3023711995660851	1.0	0.7301906214303406	4	P17612	1
Phase ii conjugation of compounds	0.3340530923672025	1.0305645123555127	0.3027450849775062	1.0	0.7301906214303406	31	P28161,O75223,Q9NZL9,P78417,Q96IU4,Q8WUX2,Q9UI30,P21266,P14550,Q96KP4,P10768,O43708	12
Glutathione synthesis and recycling	0.5363821889201801	1.0278116725610729	0.3040384244770071	1.0	0.7301906214303406	6	O75223	1
Diseases of dna repair	0.3876505961309702	1.02584226667585	0.304965939543472	1.0	0.7301906214303406	17	P38398,Q96B01,P78549	3
Dna double strand break repair	0.2844296657597288	1.0204464480923698	0.3075167747393976	1.0	0.7301906214303406	67	Q9NXR7,Q8N2W9,P35244,O00213,Q04323,Q9NY27,O96017,P38398,Q9NR33,Q9UGN5,Q15054,Q9UQ84,Q96B01,P39748,P60510,P53041,P15927,P24941,Q92993	19
Transport of connexons to the plasma membrane	0.5761320092355076	1.0193917321043664	0.3080170297442071	1.0	0.7301906214303406	5	P04350	1
Gap junction assembly	0.5761320092355076	1.0193917321043664	0.3080170297442071	1.0	0.7301906214303406	5	P04350	1
Ras activation upon ca2 influx through nmda receptor	0.5338769148188958	1.0156671544238882	0.3097879140947372	1.0	0.7304488686835775	6	Q13555,Q92796,Q13557	3
Oncogene induced senescence	0.4521616692286515	1.0137585684437591	0.3106979694963949	1.0	0.7304488686835775	10	P42771	1
Rab regulation of trafficking	0.3149059199153092	1.0107361076196968	0.3121427503650098	1.0	0.7313184092160716	40	P60520,Q9Y2L5,Q15276,Q9Y296,P62330,Q15286,P61026,Q92930,P62258,P61006	10
Tp53 regulates transcription of cell cycle genes	0.3756361214623236	1.0053843863840346	0.3147117952026881	1.0	0.7350176795852256	18	O14965,O75175,Q9Y3B8,P12004,Q9UIV1,Q99873,P30307,P06493,Q86X55,P24941,P20248	11
Activation of bh3 only proteins	0.4375867866346742	0.9996855697505196	0.3174626976162387	1.0	0.7390115255984573	11	Q96FJ2,P31946,Q9Y3B8,P61981,P62258,P63167	6
Deubiquitination	0.2735689663678534	0.9842233749130718	0.3250056951350279	1.0	0.7479871751892054	113	Q9NXR7,Q9Y5K5,P49720,Q9NZL9,P25787,Q9UPT9,Q14318,Q9Y5T5,O00487,P48556,Q13200,O00233,Q9UNM6,P62191,Q9UL46,P20618,P38398,P25788,P61586,Q9Y277,Q96FW1,Q15750,Q70CQ2,P17980,O75832,P28072,P28074,O60493,P61289,Q13485,P28066,P62333,P85037,P25789,P06493,Q06323,P54578,Q13309	38
Defects in biotin btn metabolism	0.4845700146749607	0.9736811934914636	0.3302148579501933	1.0	0.7513531931943174	7	Q96RQ3,P50747	2
Mastl facilitates mitotic progression	0.6053324143664154	0.9403480731440192	0.3470390483464574	1.0	0.7667157812705119	4	P06493,P30153	2
Vitamin c ascorbate metabolism	0.7582818641212853	0.940307218131389	0.3470599981680142	1.0	0.7667157812705119	2	P78417	1
Defective intrinsic pathway for apoptosis	0.3912728115351609	0.9344654409125296	0.3500638547136701	1.0	0.7694902069557453	15	P04179,P42771,P30307	3
The phototransduction cascade	0.5143003815254157	0.9212549238352122	0.3569173490044766	1.0	0.7749581583889247	6	P50579,P49356	2
Complex i biogenesis	0.3325902970946851	0.9159828505629778	0.3596758897707639	1.0	0.7785667126135438	26	O75380,P51970,O96000,Q8IUX1,Q9P032,Q9Y6M9,P19404,O75489,P49821,P03915,Q9BU61	11
Trna processing in the mitochondrion	0.5987408006269215	0.9127774105798672	0.3613596212126084	1.0	0.7797264164666677	4	Q99714	1
Er to golgi anterograde transport	0.2666670038676251	0.9116701707256908	0.361942371106797	1.0	0.7797264164666677	78	P54920,P47755,P56962,Q9Y296,P83436,P04350,Q9BUF5,Q9UP83,P61923,O14579,Q9H0V9,P61163,O15027,P63167,P18085	15
Platelet sensitization by ldl	0.511254643917754	0.9066594866950688	0.3645868937183372	1.0	0.7799152922853778	6	Q13362,P30153,Q16539	3
Phase 0 rapid depolarisation	0.7492981471083716	0.9051728117143594	0.3653738431130824	1.0	0.7799152922853778	2	Q13557	1
Sema4d in semaphorin signaling	0.4329208348265151	0.902287810592138	0.3669039990275493	1.0	0.7799695244561092	10	P61586,P60660	2
Defects in vitamin and cofactor metabolism	0.4133436962380603	0.9022666422859382	0.3669152410821696	1.0	0.7799695244561092	12	Q96RQ3,Q9Y4U1,P50747	3
Biological oxidations	0.2808800592183498	0.8978174714521753	0.3692828685562679	1.0	0.7818905422353821	47	P28161,O75223,Q9NZL9,P78417,Q96IU4,O43488,Q8WUX2,P00387,Q9UI30,P21266,P14550,Q15185,Q96KP4,Q86WA6,P10768,O43708,P11766	17
Smooth muscle contraction	0.4200652759259972	0.8949939146238529	0.3707903410085484	1.0	0.7835153039168733	11	P60660,P04083	2
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling	0.4307890839974216	0.8900318993929236	0.3734487577852272	1.0	0.7868012249209416	10	Q92796,Q15418,Q13555,Q13557	4
E3 ubiquitin ligases ubiquitinate target proteins	0.3686871125078149	0.8900229945760596	0.3734535391526159	1.0	0.7868012249209416	17	P50542,P12004,Q9GZS3,Q5VTR2,O95999	5
Condensation of prometaphase chromosomes	0.4304179138561818	0.8879002255759194	0.3745944233853	1.0	0.788035675862409	10	P67870,P06493	2
Ret signaling	0.4677599881729707	0.8856445577280051	0.3758090929262341	1.0	0.7894214673894266	7	P19174,Q06124,P17612	3
Maturation of sars cov 1 nucleoprotein	0.7461387250772298	0.8840914847208765	0.3766468295423335	1.0	0.7900125523635356	3	P49840,Q8IXQ6	2
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways	0.3835316690028224	0.8825996359608234	0.3774526253305137	1.0	0.7905349970049108	15	Q13404,Q15750,P52564,Q16539,P42575,Q9Y2Z0	6
Transcription of the hiv genome	0.3171085615163114	0.8808732978128231	0.378386401523934	1.0	0.7913235495787722	32	O60942,Q9Y5B9,P62487,P32780,P19387,O15514,P52657,P18615,Q15370,Q00403,Q15369	11
Pentose phosphate pathway	0.4273792014953542	0.8704748629227372	0.3840409505168511	1.0	0.8019678672557775	10	P60891	1
Toll like receptor tlr1 tlr2 cascade	0.3302827357622498	0.8550387605098104	0.392529690092827	1.0	0.8093488872927167	24	Q15418,P09429,Q13404,Q15750,P52564,Q16539,P63208,P51617,P51452	9
Tak1 activates nfkb by phosphorylation and activation of ikks complex	0.4615611546531891	0.8534490612621851	0.3934103243671663	1.0	0.8093488872927167	7	Q13404,P09429,Q15750	3
Runx3 regulates p14 arf	0.7360292052794309	0.8473636147463324	0.3967924786013981	1.0	0.8098208834567121	3	P42771,Q13951	2
E2f enabled inhibition of pre replication complex formation	0.459780054857944	0.8442299382824544	0.3985409280078031	1.0	0.8098208834567121	7	O43929,P06493	2
Traf6 mediated irf7 activation in tlr7 8 or 9 signaling	0.7324536777091598	0.8399946513771808	0.4009113854342438	1.0	0.8112893908837538	2	Q13404	1
Nade modulates death signalling	0.730974445380528	0.8291123468549736	0.4070408378043901	1.0	0.8152298867168322	3	P42575,P62258	2
Dna damage bypass	0.3221383366974145	0.8264939757132308	0.4085239340248265	1.0	0.8170478680496531	26	Q15054,P35244,P15927,Q15004,P40937,Q9NR33	6
Aggrephagy	0.3672365564622193	0.8239760117772122	0.4099531882375808	1.0	0.8173549349548437	16	Q96FJ2,Q9BUF5,Q13404,P04350,Q99497,P63167	6
Assembly of collagen fibrils and other multimeric structures	0.7293273576582249	0.8231824038974067	0.4104042736780307	1.0	0.8173549349548437	3	P07858	1
Cyclin a b1 b2 associated events during g2 m transition	0.3920597058542971	0.8221364015128114	0.4109992700515135	1.0	0.8173935062649148	13	P30307,P06493,O95067,Q9Y570,P24941,P63151,P20248	7
Separation of sister chromatids	0.2673704690093831	0.7984470250918562	0.4246111233879017	1.0	0.8340666498234787	120	Q96FJ2,Q96BD8,P49720,P25787,P36873,Q14674,Q13042,O43684,O00487,P48556,Q13200,Q13362,O00233,P04350,Q9BUF5,Q6P1K2,Q9UNM6,Q9UL46,P20618,Q9Y266,Q9NSP4,P25788,Q96DE5,Q9H900,P17980,O75832,P28072,P28074,P61289,P28066,Q13257,P62333,P25789,P50748,Q8N0S6,Q8NBT2,Q06323,Q9HBM1,Q15691,P63167	40
Class i mhc mediated antigen processing presentation	0.2703094974376318	0.7825063151646269	0.4339170754507679	1.0	0.8475409176617477	125	Q9BSL1,Q5GLZ8,Q9Y508,P49720,P09429,P25787,O95352,Q13042,O00487,P48556,Q15369,Q13200,O00233,Q9UNE7,Q9UNM6,Q9UL46,P63208,P20618,Q15370,P25788,P60059,P61081,Q9H2C0,P17980,P04439,O75832,P28072,P28074,P61289,P28066,P62333,Q05086,Q13404,P25789,Q8TDB6,Q8TBC4,Q06323,Q13309,P49427,O94822,Q63HN8	41
Synthesis of udp n acetyl glucosamine	0.5203938201518472	0.7715333194771254	0.4403908807331049	1.0	0.8590041904409464	5	O95394,Q9UJ70	2
Perk regulates gene expression	0.3514015003624176	0.7687942119050313	0.4420154855082576	1.0	0.8606476719375152	17	Q96B26,Q9Y3B2,P20042,Q13868,Q9Y2L1,Q9NQT4,Q9NPD3,P08243,Q5RKV6,Q9NQT5	10
Synthesis of ip2 ip and ins in the cytosol	0.5612907637404254	0.7587023918523815	0.4480306057812488	1.0	0.8628463223521469	4	Q96PE3	1
Extension of telomeres	0.299992801703396	0.7555005705050193	0.4499486901389016	1.0	0.8628463223521469	35	Q15054,P12004,P35244,P24941,P39748,P35250,Q9NY12,P15927,Q9NX24,P49643,P40937,P18858,P20248	13
Dual incision in tc ner	0.2979128738178614	0.7505019712483947	0.4529524370031326	1.0	0.8628463223521469	36	Q15054,P12004,P35244,P40937,P15927,P62487,P32780,P19387,O15514,Q9NR33	10
Budding and maturation of hiv virion	0.3950645716946039	0.7486104681353069	0.4540920208278503	1.0	0.8628463223521469	11	Q9NP79,Q9H9H4	2
Rna polymerase ii transcribes snrna genes	0.3004759168518689	0.7473676907743566	0.4548416425798927	1.0	0.8628463223521469	34	P08047,Q96P16,O15514,P52657,Q00403,Q9NP77	6
Interleukin 17 signaling	0.3200533809495625	0.7438235405972944	0.4569832365780772	1.0	0.8640695019186015	22	Q15418,Q13404,Q15750,P52564,Q16539,P63208,P51617,P51452	8
Insulin processing	0.3940436285934846	0.7427327733489596	0.4576434836002465	1.0	0.864167216372806	11	Q9Y4I1,Q8IYI6,Q9NV70,Q96KP1,Q8TAG9	5
Runx1 regulates expression of components of tight junctions	0.7055156702871954	0.7385035448870523	0.460208513824226	1.0	0.864858164073861	3	Q16625	1
Programmed cell death	0.2533894371891321	0.7381132805796553	0.4604456141125626	1.0	0.864858164073861	108	Q96FJ2,P49720,P09429,P25787,O00487,P48556,P62258,Q13200,P31946,P26583,O00233,Q9UNE7,Q9UNM6,Q07021,P62191,Q9UL46,P20618,O00560,P25788,P42771,Q16625,Q96GX9,P17980,O75832,P28072,P28074,P30419,P61289,P28066,P62333,P55212,P61981,P25789,Q06323,P63167,Q16611,Q9UJU6	37
G2 phase	0.704379562043806	0.7338221838153389	0.4630571183736605	1.0	0.8668803661802634	2	P24941	1
Regulation of localization of foxo transcription factors	0.4744608525965014	0.7332420736624348	0.4634107981627691	1.0	0.8668803661802634	6	P31946,P61981,Q9Y3B8	3
Erythropoietin activates phospholipase c gamma plcg	0.7038180797304963	0.7317350886326583	0.4643302752339302	1.0	0.8668803661802634	2	P07948	1
Insertion of tail anchored proteins into the endoplasmic reticulum membrane	0.3917107376823378	0.7293369469641099	0.4657955770391133	1.0	0.8668803661802634	11	P60059,O43765,P46379,Q7L5D6,P51648	5
Gab1 signalosome	0.5516853932584322	0.7200820488472858	0.4714744793685859	1.0	0.8754171995499588	4	Q06124,P41240,P62993	3
Receptor type tyrosine protein phosphatases	0.6984839977540805	0.7119866180442374	0.476473062694672	1.0	0.8824983663942586	2	P10586	1
Mitochondrial iron sulfur cluster biogenesis	0.5065062847719571	0.711663115163101	0.4766734133974621	1.0	0.8824983663942586	5	Q86SX6,Q86U28	2
Sulfur amino acid metabolism	0.388127568219063	0.7088603011394193	0.4784111727571509	1.0	0.8845623246291073	11	Q96GX9,Q13126,Q9BV57,P25325	4
Intra golgi and retrograde golgi to er traffic	0.2399732352189425	0.699965159587284	0.4839490628232867	1.0	0.8890138023403197	88	P54920,P47755,Q16706,P83436,P33908,P04350,Q9UP83,O14579,P68402,P40616,P63167,P18085	12
Heme degradation	0.5428646080145079	0.6850200330637247	0.4933312796202322	1.0	0.8976631780899277	4	P30519,P30043	2
Hsf1 activation	0.3608209696707369	0.679835331320854	0.4966087326163371	1.0	0.8994698983612227	14	P35244,P62258,Q15185	3
Synthesis of gdp mannose	0.6843583263128403	0.6651784372155414	0.5059363704398319	1.0	0.906616248460192	3	Q9Y5P6,Q96IJ6	2
Ephb mediated forward signaling	0.3283486909086502	0.6636115788281971	0.506938944561544	1.0	0.906616248460192	18	P61586,O00401,P61160,O15144,P07948,O15145,P23528	7
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway	0.6833672574833232	0.6617943037342477	0.5081030572476917	1.0	0.9075551462788958	3	Q96T60	1
Metalloprotease dubs	0.410493374058439	0.6540264800713635	0.5130947456506982	1.0	0.9141713159648576	8	P38398,Q9NXR7	2
Carboxyterminal post translational modifications of tubulin	0.4173924433670221	0.6304832878813088	0.5283784335687802	1.0	0.9274380416164004	7	P04350,Q9BUF5,Q9BVA1	3
Nostrin mediated enos trafficking	0.6754632229084874	0.6285426732688563	0.5296485009939049	1.0	0.9285195943349938	2	O00401	1
Transcriptional activation of mitochondrial biogenesis	0.3596101703826193	0.6261423330004223	0.5312215876298803	1.0	0.9301290436922688	13	Q06546,P04179,P48735	3
Tp53 regulates metabolic genes	0.2805236428268229	0.6197149804962714	0.5354454512144791	1.0	0.9310605351342854	38	Q16881,Q13131,P00403,Q9NQ88,P54619,P30044,P00390,P62258	8
Post chaperonin tubulin folding pathway	0.3822607894651994	0.6194565258983504	0.5356156531238907	1.0	0.9310605351342854	10	P04350,Q9BUF5,Q9BVA1,P36404	4
Response of eif2ak1 hri to heme deficiency	0.5257360942577665	0.6181974121655959	0.5364452157152735	1.0	0.9310605351342854	4	P08243,P20042	2
Myd88 independent tlr4 cascade	0.2912749489384657	0.6117662074945232	0.5406924505111481	1.0	0.9310605351342854	28	Q6SZW1,Q15418,P30153,P09429,Q13404,Q15750,P52564,Q16539,P63208,P51617,P51452	11
Irak1 recruits ikk complex	0.6680785063136743	0.6102266344897773	0.5417116886041828	1.0	0.9310605351342854	3	Q13404	1
Ksrp khsrp binds and destabilizes mrna	0.3409620589020215	0.6078014458852976	0.5433191702175275	1.0	0.9310605351342854	15	Q96B26,Q9Y3B2,Q13868,Q9Y2L1,Q16539,Q9NPD3,Q5RKV6,Q9NQT5	8
Pka activation in glucagon signalling	0.5226157821849959	0.6062230849325814	0.5443666253862269	1.0	0.9310605351342854	4	P17612	1
Creb1 phosphorylation through the activation of adenylate cyclase	0.5226157821849959	0.6062230849325814	0.5443666253862269	1.0	0.9310605351342854	4	P17612	1
Pka mediated phosphorylation of creb	0.5226157821849959	0.6062230849325814	0.5443666253862269	1.0	0.9310605351342854	4	P17612	1
Ctla4 inhibitory signaling	0.3890295358649932	0.6042708639260821	0.5456635740176017	1.0	0.9310605351342854	9	P07947,P30153,Q13362,Q14738,P07948,P30154,Q06124,P12931	8
2 ltr circle formation	0.4458589924974095	0.6037653167659284	0.545999681515172	1.0	0.9310605351342854	6	P12956,P17096,O75531	3
Smad2 smad3 smad4 heterotrimer regulates transcription	0.4456332018966789	0.6027679406934283	0.5466630769276173	1.0	0.9310605351342854	6	P08047	1
P75 ntr receptor mediated signalling	0.3024959209214723	0.6015258169698807	0.5474898217162876	1.0	0.9310605351342854	21	P61586,O15013,O75962,P42575,P51617,P62258	6
Toll like receptor 9 tlr9 cascade	0.293605625588311	0.5923962920949867	0.5535852486989152	1.0	0.9352946403884104	26	Q15418,P09429,Q13404,Q15750,P52564,Q16539,P63208,P51617,P51452	9
Atf4 activates genes in response to endoplasmic reticulum stress	0.3455935225729452	0.5878397483738281	0.5566398614479713	1.0	0.9352946403884104	14	Q96B26,Q9Y3B2,Q13868,Q9Y2L1,Q9NPD3,P08243,Q5RKV6,Q9NQT5	8
Synthesis of ketone bodies	0.5177683574227127	0.5877531049564823	0.5566980249108795	1.0	0.9352946403884104	4	Q9BUT1	1
Clathrin mediated endocytosis	0.2532263739053661	0.5861672639660177	0.5577631181135381	1.0	0.9352946403884104	59	O00401,Q9BT78,Q8N6T3,O15144,Q8NC96,P62330,O14657,Q9UBW8,Q9UNS2,Q92905,Q99961,O15145,P09497,Q7L5N1	14
Recruitment of mitotic centrosome proteins and complexes	0.2794914442173261	0.5808882657061305	0.5613157613909976	1.0	0.9387247573617994	36	P04350,P06493,P07437,P17612,Q9H6D7,P62258,P63167	7
Metabolism of porphyrins	0.3840032754700256	0.5784498047257545	0.5629604769917835	1.0	0.9387247573617994	9	P30043,P06132,P30519	3
Integration of provirus	0.4062891595009575	0.5768832118570861	0.5640183522209661	1.0	0.9387247573617994	7	P12956,P17096,O75531	3
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism	0.4740433120572036	0.5763154357415718	0.5644019913821834	1.0	0.9387247573617994	5	P17612	1
Hdr through single strand annealing ssa	0.2989788529270743	0.5759047669439372	0.5646795533630395	1.0	0.9387247573617994	21	Q9UQ84,P35244,P15927,P38398,Q92993	5
G2 m dna damage checkpoint	0.2667361669967067	0.5715256149598813	0.567643402020372	1.0	0.9387247573617994	42	Q9NXR7,Q8N2W9,P35244,Q9UQ84,P30307,P15927,O96017,P06493,P40937,P38398,P62258,Q92993	12
Regulation of tp53 activity	0.2495692546675428	0.5713374845711181	0.5677708969910311	1.0	0.9387247573617994	66	P19784,Q96S44,Q13362,O14965,P42771,Q13131,P35244,Q9UQ84,P54619,Q16539,P15927,P67870,O96017,P06493,P40937,P38398,P24941,Q92993	18
Cargo recognition for clathrin mediated endocytosis	0.2781514466414193	0.5690285604230887	0.5693367579983533	1.0	0.9389758378137766	36	Q9BT78,Q8NC96,O14657,Q9UBW8,Q9UNS2,Q92905,Q99961,P09497,Q7L5N1	9
Striated muscle contraction	0.4376859020375914	0.5679488634168289	0.5700696912513343	1.0	0.9390939229430334	6	P67936	1
Tp53 regulates transcription of cell death genes	0.4028739722627145	0.5606536090452655	0.5750336980852173	1.0	0.9433612402544568	7	P42575,Q92597,P55212	3
Phosphorylation of emi1	0.6525868183982088	0.5593054855335756	0.5759532522617274	1.0	0.9433612402544568	3	P06493	1
G0 and early g1	0.3699662424189187	0.5545854402824716	0.5791782500657903	1.0	0.9442512369553852	10	P12004,P24941,P06493,Q5TKA1	4
Neurotransmitter receptors and postsynaptic signal transmission	0.2535840398427151	0.5545262389125187	0.5792187535192204	1.0	0.9442512369553852	46	Q92796,Q13131,P04350,Q9BUF5,P17612,Q9Y2X7	6
Creatine metabolism	0.6505127635167864	0.5525986402076871	0.5805382733245992	1.0	0.9442890585577672	3	Q14353	1
Rhobtb gtpase cycle	0.2799316783703702	0.5424347160445665	0.5875190695383676	1.0	0.9473121624255664	30	Q15208,Q8IYB3,Q96DH6	3
Biotin transport and metabolism	0.3765315935489831	0.5406391363605886	0.5887563370701621	1.0	0.9473121624255664	9	Q96RQ3,P50747	2
Aurka activation by tpx2	0.2761147462787471	0.5401870305697206	0.5890680559308274	1.0	0.9473121624255664	35	P04350,P61163,P06493,P07437,P17612,Q9H6D7,P62258,P63167	8
Activation of ppargc1a pgc 1alpha by phosphorylation	0.6433176737127173	0.5295469835000876	0.596426060884125	1.0	0.9526715483188496	3	P54619	1
Base excision repair ap site formation	0.459037681257997	0.5165054567419575	0.6055014287735938	1.0	0.9606838311268192	5	P78549	1
Meiotic recombination	0.3313402636861356	0.5051986927461043	0.6134192883984104	1.0	0.9666666553842984	14	P35244,P24941,P11802,P38398	4
Sirt1 negatively regulates rrna expression	0.4944561426447927	0.5014139771180373	0.6160798050160494	1.0	0.9666666553842984	4	Q96EB6	1
Erk mapk targets	0.3581879764366898	0.4944026623601538	0.6210218341243041	1.0	0.9687795917650064	10	P51452,Q15418,Q16539	3
Mapk targets nuclear events mediated by map kinases	0.3581879764366898	0.4944026623601538	0.6210218341243041	1.0	0.9687795917650064	10	P51452,Q15418,Q16539	3
E2f mediated regulation of dna replication	0.3293676716133397	0.494068858137328	0.6212575503887461	1.0	0.9687795917650064	14	O43929,P30153,O43913,Q9UBD5,P06400,P06493,P49643	7
Hiv transcription initiation	0.309062523650044	0.4903287658158919	0.6239012747514736	1.0	0.9687795917650064	17	P32780,P62487,O15514,P52657,Q00403	5
Cell death signalling via nrage nrif and nade	0.3286437504203769	0.490004552372092	0.6241306774672515	1.0	0.9687795917650064	14	P42575,O75962,P62258,O15013	4
Degradation of the extracellular matrix	0.3657323008705222	0.487329307690911	0.6260249816436567	1.0	0.9687795917650064	9	P07858	1
Synthesis of diphthamide eef2	0.4901851167251835	0.4860881519840204	0.6269046668740468	1.0	0.9687795917650064	4	Q9H2P9,Q9BQC3	2
Nuclear events kinase and transcription factor activation	0.3346695479941854	0.4852360748817982	0.6275088949877494	1.0	0.9687795917650064	13	P30153,P50570,Q15418,Q16539,P27361,P51452	6
Host interactions of hiv factors	0.2252043479858607	0.4847855155178701	0.627828498354132	1.0	0.9687795917650064	96	P49720,P25787,P17096,O00487,P48556,Q13200,Q15369,O00233,Q9UNM6,Q9UL46,P63208,P20618,O15504,Q15370,P25788,P17980,P04439,O75832,P28072,P28074,P61289,P28066,P62333,Q9BXS5,P25789,P62826,Q06323	27
Class a 1 rhodopsin like receptors	0.4130713962789309	0.4641091101992316	0.6425695750245246	1.0	0.9726605179166296	6	P04083	1
Peptide ligand binding receptors	0.4130713962789309	0.4641091101992316	0.6425695750245246	1.0	0.9726605179166296	6	P04083	1
Fgfr2 alternative splicing	0.3044524127191642	0.4622893108623665	0.6438738639729802	1.0	0.9726605179166296	17	P52597,P31483,P62487,P19387,O15514	5
Ticam1 rip1 mediated ikk complex recruitment	0.6212093166139981	0.4609640957067662	0.6448243648551166	1.0	0.973004567633726	3	Q13404	1
Recruitment of numa to mitotic centrosomes	0.2608764538694658	0.4600615466126041	0.6454720441626549	1.0	0.973004567633726	39	Q9BUF5,P04350,P06493,P07437,P17612,Q9H6D7,P62258,P63167	8
Protein folding	0.2565398922756288	0.4562606355180915	0.6482025671977205	1.0	0.9746097050664576	41	P04350,Q9BUF5,Q9UHV9,P61962,P67870,P19784,Q9NQP4	7
Rhobtb1 gtpase cycle	0.2800101213966183	0.4437863859122011	0.6571970321668337	1.0	0.9816790159097212	21	Q13098,Q9BT78,Q5VTR2,Q8N684,Q15208,Q8IYB3	6
Golgi cisternae pericentriolar stack reorganization	0.3479190001008826	0.4437462594854671	0.6572260461969692	1.0	0.9816790159097212	10	P62820,P06493,O95067,P61019	4
Ras processing	0.4388246770684451	0.4393925146773341	0.6603771493534831	1.0	0.9816790159097212	5	P49356	1
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein	0.2722173380044013	0.4319372679773711	0.6657870074455072	1.0	0.9816790159097212	26	O95394,Q9Y5P6,Q9H553,Q86YN1,Q13630,P53602,P10619,Q9UJ70,Q8NFW8,Q96IJ6	10
Ovarian tumor domain proteases	0.336349252602722	0.4312282715180223	0.6663023992100867	1.0	0.9816790159097212	11	Q96FW1,P06493	2
Tp53 regulates transcription of caspase activators and caspases	0.4744165960287163	0.4309976660668971	0.6664700675223465	1.0	0.9816790159097212	4	P42575	1
Pd 1 signaling	0.6151038742279735	0.4273203607062479	0.6691460048004387	1.0	0.9816790159097212	2	P41240	1
Cobalamin cbl vitamin b12 transport and metabolism	0.4355401424280825	0.4272824993066562	0.6691735780891537	1.0	0.9816790159097212	5	Q9Y4U1	1
Defects in cobalamin b12 metabolism	0.4355401424280825	0.4272824993066562	0.6691735780891537	1.0	0.9816790159097212	5	Q9Y4U1	1
Cytochrome c mediated apoptotic response	0.403748851135706	0.4266090561080539	0.6696641004854067	1.0	0.9816790159097212	6	Q96GX9	1
Activation of gene expression by srebf srebp	0.2917183606810231	0.4248051880370539	0.6709786953718826	1.0	0.9816790159097212	18	P08047,P53602,Q03426	3
Role of lat2 ntal lab on calcium mobilization	0.6122964626614382	0.4187172109041014	0.6754228158759135	1.0	0.9816790159097212	2	P07948	1
Pi 3k cascade fgfr3	0.612296462661438	0.4187172109041011	0.6754228158759137	1.0	0.9816790159097212	2	Q06124	1
Pi 3k cascade fgfr2	0.612296462661438	0.4187172109041011	0.6754228158759137	1.0	0.9816790159097212	2	Q06124	1
Pi 3k cascade fgfr4	0.612296462661438	0.4187172109041011	0.6754228158759137	1.0	0.9816790159097212	2	Q06124	1
Stat5 activation	0.612296462661438	0.4187172109041011	0.6754228158759137	1.0	0.9816790159097212	2	Q06124	1
Stat5 activation downstream of flt3 itd mutants	0.612296462661438	0.4187172109041011	0.6754228158759137	1.0	0.9816790159097212	2	Q06124	1
Pi 3k cascade fgfr1	0.612296462661438	0.4187172109041011	0.6754228158759137	1.0	0.9816790159097212	2	Q06124	1
Nef mediated downregulation of mhc class i complex cell surface expression	0.4321418348250921	0.4148864813851218	0.6782250065997883	1.0	0.9818829078262672	5	P04439,Q9BXS5	2
Cdc6 association with the orc origin complex	0.3995523720426304	0.4100986967646517	0.6817335486827747	1.0	0.9818829078262672	6	O43929,Q9UBD5,Q99741	3
Cargo trafficking to the periciliary membrane	0.274691125160944	0.4057859646233227	0.6848998721950963	1.0	0.9839314487494258	20	Q8IYI6,P36405,P18085,P61006	4
Synthesis of pc	0.4294756678899576	0.4052585561199184	0.6852874667698465	1.0	0.9839314487494258	5	P67870,P19784	2
Synthesis of pe	0.6027512633352173	0.3900477582759012	0.6965012321434392	1.0	0.9960037760762172	2	P35790	1
Deadenylation of mrna	0.2882158406676527	0.3683383920670164	0.7126209289686867	1.0	1.0	17	Q9UIV1	1
Inactivation of csf3 g csf signaling	0.3867269542757104	0.3611779216029736	0.7179664457502115	1.0	1.0	6	Q15369	1
Processing of dna double strand break ends	0.2521949969459753	0.3564458030502909	0.7215067329628528	1.0	1.0	36	Q9NXR7,Q9NY27,Q8N2W9,P35244,Q9UQ84,P24941,P15927,P38398,P60510,Q92993	10
Signaling by csf3 g csf	0.3468446279358743	0.3551491502906463	0.7224778568881802	1.0	1.0	8	Q15369	1
Netrin 1 signaling	0.3092547616529708	0.3544800546128492	0.7229791490036783	1.0	1.0	13	O00401,Q00169,Q16539	3
Mtorc1 mediated signalling	0.3283535681416406	0.3527196582101258	0.7242986202925903	1.0	1.0	10	P06730,P31946,P62753	3
Disorders of transmembrane transporters	0.2252728644769184	0.3500983744782094	0.7262648707731951	1.0	1.0	74	O75477,O00233,P49720,P25787,Q9UNM6,O75832,Q9UL46,P20618,P61289,O15504,P28066	11
Diseases of mitotic cell cycle	0.2844687731526818	0.3478314324271984	0.7279667822484523	1.0	1.0	17	P11802,Q9UJX4,Q96DE5,P06400,Q9UJX6,Q13042,Q13309,P24941,P46100	9
Beta oxidation of pristanoyl coa	0.411778408229267	0.3436610369873761	0.731101216328033	1.0	1.0	5	O15254	1
Advanced glycosylation endproduct receptor signaling	0.3426825651972125	0.3378629871678676	0.7354664409940299	1.0	1.0	8	P47755	1
Toll like receptor cascades	0.2503702124115965	0.3359408277782553	0.7369154882844571	1.0	1.0	35	Q6SZW1,Q15418,P30153,Q99538,P07858,P09429,Q13404,Q15750,Q13546,P52564,Q16539,P63208,P51617,P51452	14
Hiv infection	0.2500502871225444	0.3335052388992663	0.7387529355268514	1.0	1.0	143	P49720,Q9NZZ3,P25787,P17096,Q9H9H4,P62487,P19387,P18074,O15514,O00487,P52657,P48556,Q15369,Q13200,O00233,Q9UNM6,Q9UL46,P63208,P20618,O15504,Q9NP79,Q00403,Q15370,P18615,P25788,P39748,P17980,P04439,O75832,P32780,P28072,P28074,P30419,P61289,P28066,O60942,P62333,Q9BXS5,P25789,P62826,Q06323,Q9Y5B9,P18858	43
Ngf stimulated transcription	0.5753560383216675	0.331399641429987	0.7403426357042928	1.0	1.0	3	P50570	1
Cell cycle checkpoints	0.2660981605660898	0.3274526456385762	0.7433255536774934	1.0	1.0	168	Q96FJ2,Q96BD8,Q9NXR7,Q8N2W9,P49720,P35244,P25787,P36873,Q9UBD5,P30307,Q13042,O43684,P40937,O00487,P48556,P62258,Q13200,P31946,Q13362,O00233,Q6P1K2,Q9UNM6,O96017,Q9UL46,P20618,Q99741,P38398,Q9Y266,Q9NSP4,P25788,P42771,Q9UQ84,Q96DE5,Q9H900,P17980,P16104,O75832,P28072,P28074,O95067,P61289,P28066,O43929,Q13257,P62333,P61981,P25789,P50748,P15927,Q8N0S6,Q8NBT2,P06493,Q06323,Q9HBM1,P24941,Q15691,P63167,Q92993	58
Asparagine n linked glycosylation	0.2368466838155374	0.3255717211340838	0.7447484106835367	1.0	1.0	126	Q9Y296,P33908,Q9UP83,Q04323,P54920,Q16706,Q9H553,P04350,Q9BUF5,P61923,Q9H0V9,P61163,P53602,O15027,Q9UJ70,P47755,Q86YN1,P83436,Q8NFW8,P18085,P56962,P04844,O14579,P63167	24
Polymerase switching on the c strand of the telomere	0.2797906981743213	0.3229067297426311	0.746765879515646	1.0	1.0	17	P35251,Q15054,P12004,Q8WVB6,P35250,P49643,P40937	7
Formation of tubulin folding intermediates by cct tric	0.2976626302450094	0.3002798425887344	0.7639637074776078	1.0	1.0	13	P49368,Q9BVA1,P78371,P50991,P40227,P50990,P04350,Q13509,Q9BUF5,P68371,P17987,Q99832	12
Gdp fucose biosynthesis	0.5701852891634054	0.2995342228320082	0.7645324639060262	1.0	1.0	2	Q13630	1
Tp53 regulates transcription of dna repair genes	0.2459871554496915	0.2962405854122989	0.7670463563726706	1.0	1.0	33	Q9Y5B9,Q14241,Q9NYV4,P62487,P32780,P19387,P18074,O15514,Q9BXW9,P38398,Q15370,P18615,Q15369	13
Telomere maintenance	0.2222906197841888	0.2927173551132927	0.7697382031984863	1.0	1.0	47	Q15054,P35244,P24941,P39748,Q9NY12,P15927,P62487,P19387,O15514,P18858	10
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	0.3208532784896218	0.2875245400299975	0.7737107146083964	1.0	1.0	9	Q9UIV1	1
Galactose catabolism	0.5648512071869878	0.2858637398402451	0.7749824867376238	1.0	1.0	2	Q96G03	1
Gpvi mediated activation cascade	0.3653680272483159	0.285410186100298	0.7753299045636399	1.0	1.0	6	P61586	1
Resolution of d loop structures	0.2929279497797865	0.2792601512067078	0.7800451849389232	1.0	1.0	13	P38398,Q96B01	2
Resolution of d loop structures through synthesis dependent strand annealing sdsa	0.2929279497797865	0.2792601512067078	0.7800451849389232	1.0	1.0	13	P38398,Q96B01	2
Formation of incision complex in gg ner	0.2808402742132638	0.2778546797346173	0.781123914771862	1.0	1.0	15	Q9UGN5,P35244,P15927,P32780,Q92889,P18074,P19447	7
Cell extracellular matrix interactions	0.3264639471639238	0.2739219106326006	0.7841446331000721	1.0	1.0	8	Q15404	1
Signaling by hippo	0.3619041079444504	0.273856696267662	0.784194751125769	1.0	1.0	6	P31946,P62258	2
Pyroptosis	0.3352567191121893	0.2737178902541854	0.7843014282004532	1.0	1.0	7	Q16611	1
Signal regulatory protein family interactions	0.551530468969381	0.2720123552241084	0.7856125193245886	1.0	1.0	3	Q06124,P62993	2
Pi5p regulates tp53 acetylation	0.3851275697888378	0.2593480685310741	0.7953666944335762	1.0	1.0	5	Q8TBX8,Q13526,P52564	3
Erks are inactivated	0.330334551588425	0.2560714210802106	0.7978956890892503	1.0	1.0	7	P30153,Q14738,P27361,P51452,P28482,P30154	6
Downregulation of erbb4 signaling	0.5513756316676175	0.2528711996678744	0.8003677456579898	1.0	1.0	2	Q96J02	1
Netrin mediated repulsion signals	0.5513756316676175	0.2528711996678744	0.8003677456579898	1.0	1.0	2	Q06124	1
Vitamin d calciferol metabolism	0.3796522558036652	0.2434139619809564	0.8076847289257247	1.0	1.0	5	Q8N2W9	1
Formation of xylulose 5 phosphate	0.5372086492558177	0.2392447515280178	0.81091580332771	1.0	1.0	3	P14550,Q00796	2
Selective autophagy	0.234981208586841	0.2294160914995695	0.8185455304465705	1.0	1.0	34	Q96FJ2,P50542,P04350,Q9BUF5,Q13404,P54619,P67870,P19784,Q99497,O96008,P63167	11
Runx2 regulates osteoblast differentiation	0.3454187745924774	0.2219244280589115	0.8243727138120405	1.0	1.0	6	P07947,P06400,Q13951,P27361,P12931	5
Signaling by erythropoietin	0.3714362494389058	0.220451852909139	0.8255192657635422	1.0	1.0	5	P19174,P46109,P07948	3
L1cam interactions	0.2196783246214044	0.2045258511563522	0.8379425926279016	1.0	1.0	43	Q92796,P04350,P67870,P19784,O00560	5
Apc cdc20 mediated degradation of nek2a	0.273826988297017	0.2016661442209444	0.8401777317607668	1.0	1.0	13	Q13042,O43684,Q96DE5	3
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components	0.273826988297017	0.2016661442209444	0.8401777317607668	1.0	1.0	13	Q13042,O43684,Q96DE5	3
Prolonged erk activation events	0.3372681281618959	0.1982018003596078	0.8428871789463965	1.0	1.0	6	P31946,Q9ULH0,P27361,P46109,P28482	5
Phosphorylation of the apc c	0.2716333552611494	0.1935352780080483	0.8465397804276018	1.0	1.0	13	Q13042,P06493	2
Rho gtpases activate formins	0.208119517803466	0.1932756392120393	0.84674310370827	1.0	1.0	74	P61586,Q96BD8,Q9BUF5,P04350,P36873,Q6P1K2,P50748,P35080,Q8N0S6,P07737,Q9H900,O43684,P63167	13
Activation of nima kinases nek9 nek6 nek7	0.3607030453569145	0.1922246790149618	0.8475662153056895	1.0	1.0	5	P06493,O95067	2
Transcriptional regulation by tp53	0.2347628496388109	0.1872997156969151	0.851425645883233	1.0	1.0	142	Q13131,P12004,P35244,Q9NQ88,P54619,P30307,Q9NYV4,P62487,P19387,P18074,P40937,O15514,P19784,Q99873,P62258,Q15369,Q16881,P31946,Q13362,O75175,P52564,P30044,O96017,Q86X55,P00390,P38398,Q15370,P18615,O14965,P42771,Q9H3P2,Q9UQ84,Q9UIV1,Q16539,P67870,P32780,Q9BXW9,P42575,Q96S44,P55212,P00403,P61981,P15927,Q92597,P06493,Q9Y5B9,P24941,Q14241,Q92993,Q13526	50
Apobec3g mediated resistance to hiv 1 infection	0.510187214264699	0.1838014724013102	0.8541692010088382	1.0	1.0	3	P17096	1
Apc c cdc20 mediated degradation of cyclin b	0.2722717930989107	0.1793523063434741	0.8576610781075551	1.0	1.0	12	Q13042,P06493	2
Gap junction trafficking and regulation	0.2662762643358011	0.1743852657885547	0.8615626931027696	1.0	1.0	13	P04350,Q9BUF5	2
Golgi to er retrograde transport	0.2067482198346854	0.1735192749983241	0.862243278424065	1.0	1.0	71	Q96FJ2,Q9Y3B3,P54920,P62820,P04350,Q9BUF5,P61923,Q14807,P61163,P84085,P52907,P48444,P47755,Q9BVA1,Q8N6T3,Q15042,Q9NZ32,P18085,Q13561,O14579,P68402,P63167	22
Camk iv mediated phosphorylation of creb	0.5027451660569197	0.1700434937806056	0.8649759316132846	1.0	1.0	3	Q13557	1
Inhibition of replication initiation of damaged dna by rb1 e2f1	0.3010964295754865	0.1626935057402579	0.8707597605313209	1.0	1.0	7	P49642,P30153,Q14181,P06400,P49643,P30154	6
Glycerophospholipid biosynthesis	0.223143052391836	0.1613592960260568	0.87181042358023	1.0	1.0	30	Q9NPH0,Q8NAN2,O94830,P67870,O96017,P48651,P19784,P48739	8
Signaling by wnt in cancer	0.2918238742834068	0.1580203404948603	0.8744407706903614	1.0	1.0	8	Q13362,Q13363,P30153	3
Transmission across chemical synapses	0.2049667793438903	0.1513951712199211	0.8796639983681125	1.0	1.0	57	Q92796,Q13131,P04350,P17612,Q9Y2X7,Q96QD8	6
Hdr through mmej alt nhej	0.2882522319278721	0.1478255122053667	0.8824804747064474	1.0	1.0	8	Q9UGN5,P39748	2
Suppression of apoptosis	0.317882898902647	0.147280055733837	0.8829109740201773	1.0	1.0	6	Q63HN8	1
Signalling to erks	0.264002251618354	0.1400803630840052	0.8885964955929706	1.0	1.0	11	P31946,P62993,Q16539,P28482,Q9ULH0,P27361,P46109,Q02750,P11233,P12931	10
Lipophagy	0.3674157303370791	0.1395955394802998	0.8889795650920762	1.0	1.0	4	O60664,P54646,P54619	3
Death receptor signalling	0.2180056201980911	0.1360949768821807	0.8917461984500412	1.0	1.0	32	P61586,O15013,O95429,Q15750,O75962,P42575,P51617,P62258	8
Trafficking and processing of endosomal tlr	0.4825233145446976	0.1360160254760626	0.8918086122028195	1.0	1.0	3	P07858	1
Translation	0.2749587899441476	0.1342993894005763	0.8931658360567543	1.0	1.0	224	Q7Z2W9,P49458,P62841,P09132,Q9Y285,Q9Y3U8,P63220,P61513,P60842,P39019,P60059,P49770,Q9BYD3,P82933,Q9H2U2,Q9UGM6,O43324,P20042,O75821,P06730,P61927,P62888,O15372,P62854,P62701,P37108,P26373,P62277,P62263,P61247,Q9BYC9,P56537,P62847,Q14232,Q07020,P61313,Q9UBQ5,P08708,P32969,P62899,P51571,P61254,O00303,Q7L3T8,P62913,Q12904,P82663,P62081,P42766,Q9Y2Q9,P46778,P46776,P62495,P62857,Q15056,P63173,Q15181,P62906,Q05639,P62273,P62249,P61009,P62753,P54577,P05386,Q13144,P08865,P18621,O60841,Q9NR50,Q9UI30,P05388,P62244,P50914,P46777,P24534,P62910,P84098,Q96I59,Q9NP92,Q14240,P04844,P30050,P60866,P62829,P62280	86
Heme biosynthesis	0.3352065186850268	0.1335631842685855	0.8937479979768268	1.0	1.0	5	P22830,P36551,P06132,P08397	4
Interleukin 3 interleukin 5 and gm csf signaling	0.2682754050433528	0.1321115088015823	0.894896092996966	1.0	1.0	10	P62993,P07948,P17612,P46109,Q06124	5
Signal transduction by l1	0.2664449802540432	0.1270281500332783	0.8989181185167094	1.0	1.0	10	P67870	1
Translocation of slc2a4 glut4 to the plasma membrane	0.2084240764657172	0.1227949796671586	0.9022694498194516	1.0	1.0	41	Q9Y4I1,P04350,Q8IYI6,Q9BUF5,P54619,Q8TAG9,P61026,P62258,P61006	9
Protein protein interactions at synapses	0.2369375858434276	0.122026540861763	0.9028779987720528	1.0	1.0	16	Q92796,O95197,Q9HCM4,Q13136,P10586,Q9UJU6	6
Signaling by alk in cancer	0.2132619334018721	0.1166194449630033	0.9071616280159592	1.0	1.0	34	Q9H6R7,P62753,P67936,P63208	4
Signaling by egfr	0.2514076576576584	0.1150273764059657	0.9084234228286284	1.0	1.0	12	P19174,P01111,P41240,P62993,Q13685,P42566,P22681,Q99961,P60953,Q06124,P12931	11
Protein ubiquitination	0.2156465223872018	0.1112783146179139	0.9113956510214763	1.0	1.0	25	P50542,P12004,Q9GZS3,Q5VTR2,O95999,P49427	6
Regulated necrosis	0.2151201256874391	0.1079727924503023	0.9140172744906964	1.0	1.0	20	O00560,P09429,Q16611	3
Diseases of programmed cell death	0.2094111059781508	0.101997101068475	0.9187589760968452	1.0	1.0	29	P04179,P42771,P30307	3
Rsk activation	0.3452247191011157	0.1009781912966502	0.9195677724970226	1.0	1.0	4	P27361,Q15418,P51812	3
Rhov gtpase cycle	0.2123652522105156	0.0975173598437743	0.9223155487718772	1.0	1.0	21	O43639,Q9Y2X7	2
Purine ribonucleoside monophosphate biosynthesis	0.2538923124899205	0.0949653195064997	0.9243423734131448	1.0	1.0	10	P20839	1
Pp2a mediated dephosphorylation of key metabolic factors	0.4507160909856676	0.0923524742988747	0.9264179980046868	1.0	1.0	3	P30153,P30154	2
Nrage signals death through jnk	0.2512661789533033	0.0888747150856743	0.9291814784547026	1.0	1.0	10	Q92888,O15013,Q9NY61,P63000,Q92974,O75962,Q9H8V3,Q12802,Q14344	9
Regulation of pyruvate dehydrogenase pdh complex	0.2576645309238029	0.0887290660001528	0.9292972323058168	1.0	1.0	9	Q15118,Q15120	2
Oncogenic mapk signaling	0.2062816447509277	0.0882312606359502	0.9296928718018838	1.0	1.0	34	P62140,P31946,P51114,P36873,Q99956,O95352,Q13555,Q9NRY5,Q13557	9
Calcineurin activates nfat	0.4567658618753701	0.0876230536660752	0.9301762784759088	1.0	1.0	2	Q12968	1
Rhobtb3 atpase cycle	0.4434147711317012	0.0839818917981105	0.933070829151856	1.0	1.0	3	Q15345,O60664	2
Gastrin creb signalling pathway via pkc and mapk	0.2637053696935598	0.0742644388228109	0.940799972574388	1.0	1.0	7	P17252,P62993,P27361,Q15418,P51812,P28482	6
Ca dependent events	0.2484089493423271	0.0691726906146627	0.9448521607575764	1.0	1.0	9	P17612,Q13555,Q13557	3
Sealing of the nuclear envelope ne by escrt iii	0.2334396376623737	0.0651982193674384	0.948016178853328	1.0	1.0	11	P04350	1
Pyruvate metabolism	0.2103347791474364	0.0597074204210322	0.9523886616401298	1.0	1.0	17	Q15118,Q04760,Q15120	3
Erythropoietin activates ras	0.3107705977448149	0.0564176596324737	0.9550090890084464	1.0	1.0	4	P46109,P07948	2
Aberrant regulation of mitotic exit in cancer due to rb1 defects	0.2249986032752902	0.0550757365194073	0.9560781262503312	1.0	1.0	12	Q9UJX4,Q96DE5,Q13042,Q9UJX6,Q13309	5
Senescence associated secretory phenotype sasp	0.1981873772230025	0.0547032579711408	0.956374873765732	1.0	1.0	25	P24941,Q13042,P42771,Q96DE5	4
Regulation of cholesterol biosynthesis by srebp srebf	0.1954103540312669	0.0481247956012651	0.9616167850645696	1.0	1.0	26	P53602	1
Potential therapeutics for sars	0.1896729211533499	0.0458069799621454	0.9634640954471788	1.0	1.0	40	Q99720,P07437,P20839,P49356	4
Neuronal system	0.1847290155651983	0.045647571748725	0.963591151893451	1.0	1.0	68	Q92796,Q13131,P04350,P10586,P17612,Q9Y2X7,Q96QD8	7
Sulfide oxidation to sulfate	0.3983717012914233	0.0400462803695893	0.9680562294654408	1.0	1.0	2	Q16762	1
Fcgr activation	0.3886548722269028	0.0388260298195566	0.9690290916824208	1.0	1.0	3	P07948,P12931	2
Alpha oxidation of phytanate	0.3863669561503511	0.03754135478035	0.970053367025398	1.0	1.0	3	P51648	1
Hsf1 dependent transactivation	0.2015219842164636	0.037004641763174	0.9704813046851376	1.0	1.0	16	P54652,P50454,P25685,Q92598,P08238,P11142,P42345,Q13557,Q96B36,Q15185,P04792,Q8N122,P0DMV9,Q02790,Q13555	15
The activation of arylsulfatases	0.3899494665918163	0.0358542120202274	0.9713986058861293	1.0	1.0	2	P15289	1
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function	0.2098000563221694	0.0352390502879146	0.9718891239288724	1.0	1.0	13	Q03164,Q15291,P62805,Q9UBL3,P61964,Q9HCE1,P16104,Q96ST3,Q13547,Q13951,Q99873,O15047	12
Costimulation by the cd28 family	0.1979137299125954	0.0351796644790812	0.9719364775876274	1.0	1.0	17	Q13177,P07947,P31751,P41240,Q14738,Q13362,P62993,P30153,Q6R327,P07948,P30154,P42345,P60953,Q06124,P63000,P12931	16
Peroxisomal lipid metabolism	0.2118833557984878	0.0337979294220631	0.9730382870856528	1.0	1.0	12	P51648,Q9UKG9,O15254	3
Egfr downregulation	0.2509836987071448	0.0327335821186937	0.9738870435749328	1.0	1.0	6	P62993,P42566,P22681,Q99961,P60953	5
Caspase mediated cleavage of cytoskeletal proteins	0.2264230104126574	0.0323320435294404	0.974207255515287	1.0	1.0	9	P55212,Q9UJU6	2
Signalling to ras	0.2635571789828636	0.0320729288332233	0.9744138919615076	1.0	1.0	5	P11233,P12931,P62993,Q16539	4
Constitutive signaling by akt1 e17k in cancer	0.2344672476806313	0.0294187834341532	0.976530592273557	1.0	1.0	7	P31751,O15111,Q6R327,P42345,Q96B36,P49840	6
Lysosome vesicle biogenesis	0.1939465873215713	0.0252985770320936	0.9798168089330348	1.0	1.0	16	P09497,Q9BXS5,Q9Y6B7,P49407,Q10567	5
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1	0.2426748491903939	0.0246699273151676	0.9803182423030656	1.0	1.0	6	Q13404,Q15750	2
Mhc class ii antigen presentation	0.1763852081247729	0.0228160930110811	0.981796970999891	1.0	1.0	58	Q96FJ2,P50570,P68371,P10619,P53634,Q99538,P04350,Q9BUF5,Q14807,P61163,P52907,Q9UJW0,O94979,O75935,P47755,Q9BVA1,P07858,Q9NZ32,Q15436,O43237,Q10567,Q13561,Q9BXS5,Q9Y6G9,P53680,P63167	26
Golgi associated vesicle biogenesis	0.1838281615050268	0.0223900038870162	0.9821368540970844	1.0	1.0	31	P54920,Q8NC96,Q9Y6B7,Q9BXS5	4
Neurotransmitter clearance	0.3192026951151173	0.0176250991527783	0.9859379335568572	1.0	1.0	2	P21964	1
Influenza infection	0.199500637407208	0.0127490208819264	0.9898280286282268	1.0	1.0	131	P62847,P62487,P62841,P19387,O15514,P08865,P62913,P18621,P62081,Q07020,Q9Y3U8,P63220,P61313,P61513,P05388,P08708,P42766,P62244,P50914,O15504,P46777,P62910,P84098,P32969,P46778,P62899,P46776,P62857,P63173,P61254,O00505,O00629,P62906,P62273,P62249,P62753,P19525,P30050,P61927,P60866,P62888,P62854,P62826,P05386,P62829,P26373	46
Traf6 mediated induction of tak1 complex within tlr4 complex	0.294398643112264	0.0119895472829802	0.9904339545177444	1.0	1.0	3	Q15750	1
Copii mediated vesicle transport	0.1785472422403838	0.0114679873367412	0.990850070519394	1.0	1.0	32	P54920,P56962,Q9Y296,Q9H0V9	4
Bmal1 clock npas2 activates circadian gene expression	0.2687578479802714	0.0102843354591311	0.9917944321664393	1.0	1.0	3	Q86X55	1
Serine biosynthesis	0.2604331100901669	0.0099512698495976	0.9920601664708428	1.0	1.0	3	P78330	1
Signaling by ntrks	0.1759206798866883	0.0068291700105935	0.994551153038973	1.0	1.0	34	P50570,P63010,Q8WX92,P27361,Q15418,P51452,P28482,P19174,P31946,P30153,P09496,Q14738,Q14839,O94973,Q9ULH0,P46109,Q02750,P63000,P11233,P12931,P01111,O95782,P61586,Q16539,Q00610,Q8IV63,Q06124,P51812,P30154,P62993,P40763,Q00535,P53680	33
Peptide hormone metabolism	0.1748713652178067	0.0041615481642855	0.9966795745548038	1.0	1.0	16	Q9Y4I1,Q8IYI6,P61009,Q9NV70,Q96KP1,Q8TAG9	6