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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Electron transport chain oxphos system in mitochondria 0.590567267996241 3.4774713743699492 0.0005061670954213 0.266816291418267 0.1839897339025611 53 P21912,P14406,O43676,P06576,O75964,P24539,P12235,P05141,P13073,O96000,P47985,Q9UDW1,O95168,P36542,P22695,O14949,P03886,P00403,P00846,P20674,Q7KZN9,Q9Y6M9,P56134,P56385 24
Sphingolipid metabolism integrated pathway 0.8992958100782094 2.5031983625639276 0.0123076541943638 0.9994952284639046 0.5103356871443749 8 Q96G23,Q06136,Q13510,P27544,Q16880,O95470 6
Sphingolipid metabolism overview 0.8992958100782094 2.5031983625639276 0.0123076541943638 0.9994952284639046 0.5103356871443749 8 Q96G23,Q06136,Q13510,P27544,Q16880,O95470 6
Nonalcoholic fatty liver disease 0.483432474693892 2.455438907333229 0.0140712668106772 0.999831225844844 0.5103356871443749 53 P22695,O14949,P00403,P13073,P21912,P14406,P31751,O96000,P20674,O43676,P47985,Q9P0J0,Q86Y39,Q16611,P19838,Q9UDW1,Q9Y6M9,O95168 18
Cholesterol biosynthesis with skeletal dysplasias 0.8747446847336718 2.3239333893116436 0.0201290643890557 0.9999961405890684 0.5103356871443749 6 Q15125,Q14739,Q15392 3
Oxidative phosphorylation 0.5551097045856738 2.31354137382436 0.0206928927422238 0.9999972880004578 0.5103356871443749 33 P03886,Q15904,P00846,Q9Y6M9,O75787,O96000,Q86Y39,P06576,O75964,P24539,P56385,O95168 12
Mitochondrial complex iv assembly 0.7848523581698689 2.0956185527357554 0.0361160420961854 0.9999999998388712 0.6171655385151038 10 P00403,Q9Y2R0,P13073,P14406,Q7KZN9 5
Kennedy pathway from sphingolipids 0.8401009653216643 2.045859394898693 0.0407702063402402 0.9999999999917092 0.6171655385151038 5 Q9Y6K0,O95470,P35790 3
Statin inhibition of cholesterol production 0.8371801585025135 2.0338486395657007 0.0419668587111847 0.9999999999961428 0.6171655385151038 5 Q8WTV0,Q14534,P37268 3
Metabolism of spingolipids in er and golgi apparatus 0.8678000253107556 2.0266795500725636 0.0426951951792113 0.9999999999975802 0.6171655385151038 4 Q06136,O95470 2
Overlap between signal transduction pathways contributing to lmna laminopathies 0.693536512794896 2.008311218052712 0.0446102305489761 0.9999999999992908 0.6171655385151038 16 O75844,P42167,P55209,P50402,O60725,P49354,P11802 7
Sphingolipid pathway 0.7712667700867246 1.990520563559746 0.0465336210557991 0.9999999999997938 0.6171655385151038 9 Q96G23,Q06136,Q13510,P04062,Q16880,O95470 6
Sphingolipid metabolism in senescence 0.7390151814040858 1.9806053902404517 0.0476355439894353 0.9999999999998984 0.6171655385151038 12 Q96G23,P16278,Q06136,Q13510,P04062 5
Omega3 omega6 fatty acid synthesis 0.8198478295410099 1.96227516806494 0.0497304566299472 0.9999999999999736 0.6171655385151038 5 O15254 1
Oxidation by cytochrome p450 0.8182517244731051 1.9556584858751151 0.0505053982150789 0.999999999999984 0.6171655385151038 5 O43169,P16435 2
Cholesterol metabolism with bloch and kandutschrussell pathways 0.5453802749354928 1.9357883307029888 0.0528936307106013 0.9999999999999966 0.6171655385151038 24 Q15125,Q15392,P37268,Q14534,Q14739,P48449,Q16850,Q15800 8
Proteoglycan biosynthesis 0.8088147853438356 1.9164506125458336 0.0553077638106231 0.9999999999999992 0.6171655385151038 5 Q8TB61,Q8NCH0 2
Mitochondrial complex i assembly model oxphos system 0.5035280166111274 1.8231683005224564 0.0682779045692909 1.0 0.6171655385151038 29 P03886,Q9NPL8,Q96CU9,O96000,O43676,Q9P0J0,Q9Y6M9,O95168,Q7L592 9
Glycerophospholipid biosynthetic pathway 0.7343981756729987 1.8227533741684092 0.0683407524114418 1.0 0.6171655385151038 9 Q9BTU6,O00116,O95674,Q9HCL2,Q9Y6K0 5
Acquired partial lipodystrophy barraquersimons syndrome 0.7789834380353943 1.791559597951646 0.0732035398334387 1.0 0.623068862342214 5 Q03252,O60725,P49354,P20700 4
Triacylglyceride synthesis 0.8038823865258303 1.7668799123258332 0.0772483418238307 1.0 0.623068862342214 4 Q9HCL2,O00116,Q99943 3
Ferroptosis 0.5344797756003723 1.7222715735315608 0.0850203346227616 1.0 0.6266892316463777 23 P08195,P16435,Q9Y277,P09601,Q15043,P02786,P37268,P04792,P45880 9
Ketogenesis and ketolysis 0.7215660892309309 1.7008220238904344 0.0889764123441758 1.0 0.6266892316463777 7 P23786,O43772,P11166,P53985 4
Glycosaminoglycan degradation 0.7156125284451794 1.6499321912660756 0.098956805753291 1.0 0.6266892316463777 6 P54802,P16278,P06865,P08236 4
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.7065784583129319 1.6103240955803673 0.1073271215991427 1.0 0.6266892316463777 6 P07099 1
Proximal tubule transport 0.6711015743421 1.6016340051186924 0.1092365665731254 1.0 0.6266892316463777 11 P11166,P08195,P08183,Q9Y5K8,O15439,P05023 6
Ccl18 signaling pathway 0.6767881703989719 1.5898752214267806 0.1118629339693191 1.0 0.6266892316463777 10 P07196,P11166,P08670,Q86UE4 4
Vitamin d metabolism 0.8952398641220043 1.5787400264832074 0.1143956998341613 1.0 0.6266892316463777 3 P04062 1
Intracellular trafficking proteins involved in cmt neuropathy 0.67200014696335 1.5669404670638205 0.1171286076320186 1.0 0.6266892316463777 10 P07196,Q6UWE0,P04792,Q9NR77 4
1q211 copy number variation syndrome 0.6698530923276039 1.5566436707432898 0.1195551093113702 1.0 0.6266892316463777 10 Q9NPH0 1
Degradation pathway of sphingolipids including diseases 0.6919109575080759 1.545763647937862 0.1221616593544223 1.0 0.6266892316463777 6 P17900,P16278,O43681 3
Nocgmppkg mediated neuroprotection 0.6821295289502338 1.524245124855595 0.1274474895008333 1.0 0.6456637278017422 7 P07196,P30536,Q13555 3
Familial partial lipodystrophy fpld 0.6580548207567831 1.4391350842769906 0.1501122533830914 1.0 0.6775989132742326 8 O75844,P20700,P31751,Q03252,O60725 5
15q112 copy number variation syndrome 0.6767561393489411 1.3544500873694347 0.1755928271088764 1.0 0.6878900446417137 5 Q96CW5,Q9BSJ2,Q7L576,Q96RT7 4
Nephrotic syndrome 0.6048138619669182 1.3533322783027997 0.1759495017087544 1.0 0.6878900446417137 13 Q14108,O75844 2
Vitamin d receptor pathway 0.6039998345919771 1.3490772668057445 0.1773121493001279 1.0 0.6878900446417137 13 Q96KA5,P08183,P20020,Q92604 4
Mitochondrial complex iii assembly 0.632366279508278 1.345620344499313 0.1784249871093515 1.0 0.6878900446417137 9 P22695,O14949,Q6DKK2,Q9UDW1 4
Influence of laminopathies on wnt signaling 0.6123953346680016 1.311548085804935 0.189672659078854 1.0 0.6962343546569045 11 O60725,O75844 2
Estrogen receptor pathway 0.8069042378422293 1.249672444919396 0.211419227102745 1.0 0.7286577147094284 3 Q9HCL2 1
Pregnane x receptor pathway 0.6144306356801559 1.2008504361887484 0.2298092232610127 1.0 0.7375552558062869 6 P08183 1
Endothelin pathways 0.5901720015491475 1.1704398388194452 0.2418240113296401 1.0 0.7465029710830033 10 P42892,P00403,P16615 3
Glycerolipids and glycerophospholipids 0.6317490881021409 1.1594806479538624 0.2462603202340423 1.0 0.7469279518881081 5 Q9HCL2 1
Nad metabolism sirtuins and aging 0.6302888399821801 1.1531554492357914 0.2488465857423265 1.0 0.7469279518881081 5 P43490 1
Transcription factors regulate mirnas related to cardiac hypertrophy 0.6318173627741485 1.048484197099126 0.2944155794105332 1.0 0.8085654757189715 4 P31751 1
Pkcgamma calcium signaling pathway in ataxia 0.7508561643835682 1.041894437503872 0.2974606233396288 1.0 0.8085654757189715 3 P23634,Q15118 2
Progeriaassociated lipodystrophy 0.5612997618764533 1.029717058888098 0.3031428452773399 1.0 0.8089494905883061 10 Q03252,O60725,O75844,P20700 4
Metabolic pathway of ldl hdl and tg including diseases 0.7451484018265148 1.0209170605820708 0.3072937354276439 1.0 0.8089494905883061 3 P07355,Q8WTV0 2
Metapathway biotransformation phase i and ii 0.4513488675752343 1.0205240570730136 0.3074799858190462 1.0 0.8089494905883061 22 P78417,Q7LGA3,P07099,P21964,Q16850,Q8NCH0 6
Mitochondrial immune response to sarscov2 0.5551445567066725 0.99977881805441 0.3174175588117234 1.0 0.827987078942921 10 Q86UT6,Q9Y6M9 2
Eicosanoid metabolism via lipooxygenases lox 0.5679538447507114 0.9930870076315358 0.3206675549657731 1.0 0.8289786206320036 6 Q8N8N7,O15254 2
7oxoc and 7betahc pathways 0.5456454908331898 0.9536618651487488 0.3402548294114738 1.0 0.8465591891617192 10 O15118 1
Rala downstream regulated genes 0.5658105180508498 0.8759388214886364 0.3810632933776694 1.0 0.8614730379102679 5 Q96KP1,P11233,P63000 3
Adipogenesis 0.4984265755046462 0.8678150916365099 0.3854955669062583 1.0 0.8614730379102679 15 O75376,O75844,P17096,O00767,P43490 5
Lung fibrosis 0.5296912361675868 0.8239140526931467 0.4099883950701906 1.0 0.8614730379102679 6 P09601 1
Eicosanoid metabolism via cyclooxygenases cox 0.528562200369957 0.8189727227355905 0.4128019765337845 1.0 0.8636437256491805 6 Q8N8N7,O15254 2
Glycosylation and related congenital defects 0.5170396728583351 0.8157846702734058 0.4146233024422656 1.0 0.8645036884255403 10 O60762,Q9BT22,Q2TAA5 3
Ovarian infertility 0.5746161389151431 0.8131040456427655 0.4161584071296231 1.0 0.8647630629507084 4 P11802,O75376 2
Cellular proteostasis 0.5732797794859441 0.8077088620494226 0.4192582007935441 1.0 0.8653376332876854 4 Q9UHV9 1
Mitochondrial long chain fatty acid betaoxidation 0.4878326131366978 0.7731650456278569 0.4394247098711066 1.0 0.8819371547321191 14 O43772 1
Zinc homeostasis 0.8601997146932965 0.7667270487825834 0.4432438180304077 1.0 0.8819371547321191 2 Q92504 1
S1p receptor signal transduction 0.5125222158705574 0.7648104992914436 0.444384394837551 1.0 0.8819371547321191 8 P31751 1
Vitamin dsensitive calcium signaling in depression 0.5142643761773426 0.7631229513538645 0.4453900734702714 1.0 0.8819371547321191 7 P23634,Q8NB78,P20020 3
Drug induction of bile acid pathway 0.8587731811697348 0.7620936581678301 0.4460041076133065 1.0 0.8819371547321191 2 P08183 1
Vitamin b12 disorders 0.6700736421216144 0.7513554569711439 0.4524387621512056 1.0 0.8867246724681047 3 Q96EY8 1
Camkk2 pathway 0.4876678071266439 0.7154158124720945 0.474352144580751 1.0 0.8935597189527344 12 O76024,P09601 2
Myd88 distinct inputoutput pathway 0.8388017118402298 0.6980351940474895 0.4851551846279784 1.0 0.8965478461010241 2 P61088 1
Irinotecan pathway 0.8359486447931262 0.6890150119911402 0.4908138206124564 1.0 0.8991528440373018 2 O15118 1
Nuclear receptors in lipid metabolism and toxicity 0.8356633380884184 0.6881148993037685 0.4913804286337619 1.0 0.8991528440373018 2 P08183 1
Inclusion body myositis 0.650043807973705 0.6823921612817501 0.4949910110345854 1.0 0.9027843791913646 3 P19838 1
Type i collagen synthesis in the context of osteogenesis imperfecta 0.4747704397927529 0.6757318686007749 0.4992108985431622 1.0 0.9027843791913646 13 Q32P28,O15460,P13674,Q96AY3,O75718,Q9NVV0 6
Cholesterol biosynthesis pathway 0.4737191024952063 0.6704201787887186 0.5025899747284177 1.0 0.9034828577962464 13 Q15800,Q16850,Q14534,P48449 4
Mrna protein and metabolite inducation pathway by cyclosporin a 0.8248216833095597 0.6541760643953537 0.512998380494742 1.0 0.9041699031927865 2 P08195 1
Preimplantation embryo 0.4806012305431031 0.6224687614081075 0.5336336785446076 1.0 0.9240605789487132 8 P05023,Q99729 2
Sarscov2 and covid19 pathway 0.6199486778530495 0.5822483491650896 0.560399410745698 1.0 0.9427208156064496 3 Q8WTV0 1
Nuclear receptors metapathway 0.3157442639051335 0.5810523618557222 0.5612051638419986 1.0 0.9427208156064496 51 Q92504,P11166,P09601,P08183,Q15043,O15439,P11802,Q9HCL2,Q15067,P23786 10
Mecp2 and associated rett syndrome 0.3634153577875744 0.5601742754167197 0.5753605717051997 1.0 0.9547676789257268 24 Q03518,Q99640,P67809,Q00013,P35637 5
Allograft rejection 0.4588506221059416 0.5352126623722699 0.5925028113447484 1.0 0.9547676789257268 9 P10321,P08183,P08670 3
Vitamin a and carotenoid metabolism 0.6039396198597249 0.5310223677572231 0.5954032791222255 1.0 0.9547676789257268 3 Q8WTV0 1
Autosomal recessive osteopetrosis pathways 0.6027397260274109 0.5272474991953421 0.5980217274342183 1.0 0.9547676789257268 3 P51798,P19838 2
Vitamin b12 metabolism 0.4580924895036178 0.5255718966923433 0.5991856871981294 1.0 0.9547676789257268 8 Q96EY8,P22033,Q8WTV0,P19838,P01130 5
Nanomaterial induced apoptosis 0.4585974933643493 0.5233998947496193 0.6006959974189343 1.0 0.9547676789257268 6 O43464,O95831 2
Dna replication 0.3380210253508454 0.4922064029116469 0.622573438500378 1.0 0.9547676789257268 34 Q9Y619,Q14566 2
Pparalpha pathway 0.4503096528022285 0.4903531353172616 0.6238840331711 1.0 0.9547676789257268 7 P11802,P23786 2
Relationship between inflammation cox2 and egfr 0.4662871943745116 0.4748421636884282 0.6348994776589896 1.0 0.9547676789257268 5 P31751 1
Ethanol effects on histone modifications 0.4395035075330379 0.4698797981953168 0.6384408982483314 1.0 0.9547676789257268 11 P00374 1
Gastric cancer network 2 0.4059504293065309 0.4068426886516267 0.6841235312354397 1.0 0.9644591260802128 16 Q14739 1
Male infertility 0.3406066057670505 0.3953389499078352 0.6925927577885869 1.0 0.9644591260802128 24 Q15165,P08183 2
Histone modifications 0.4181119974637615 0.3870979793689384 0.6986836734663475 1.0 0.9644591260802128 12 Q01105,Q9H7B4,O15047 3
Regulation of apoptosis by parathyroid hormonerelated protein 0.4194669322516459 0.3698900605063359 0.7114644076120176 1.0 0.975677140640194 7 Q16611,Q07820 2
Primary focal segmental glomerulosclerosis fsgs 0.3831843988698328 0.3494539874983589 0.7267485086265619 1.0 0.9800426372886428 18 Q14108 1
Arrhythmogenic right ventricular cardiomyopathy 0.4059643579042326 0.346407338111686 0.7290366110988926 1.0 0.9800426372886428 13 P05556,P50402,P16615 3
Hair follicle development organogenesis part 2 of 3 0.4449093999579999 0.3389310870026905 0.734661645000303 1.0 0.983758333675198 4 P19838 1
Fatty acid betaoxidation 0.3670619081004866 0.3363391494551064 0.7366151307616899 1.0 0.983758333675198 20 O43772,P23786 2
Aspirin and mirnas 0.439588105169079 0.3226849211634932 0.7469338729381432 1.0 0.9869415659086692 4 O15439,Q15118 2
Omega9 fatty acid synthesis 0.4203312392918299 0.3149141560986222 0.7528268330529508 1.0 0.9869415659086692 5 O60488,O00767,P49327,O95573 4
Folate metabolism 0.3763951031701019 0.2856498572643969 0.7751463131367207 1.0 0.9959360229503422 17 Q8WTV0,P00374 2
Oxysterols derived from cholesterol 0.3971630410084666 0.285421150184732 0.7753215056491092 1.0 0.9959360229503422 9 O14975,Q15125,Q9Y305 3
Nucleotidebinding oligomerization domain nod pathway 0.3970993922849001 0.2851870637645525 0.7755008306474416 1.0 0.9959360229503422 9 Q9P0J0 1
Hedgehog signaling pathway wp4249 0.3898886032562073 0.2702299876249778 0.7869833237951331 1.0 0.998185071330168 6 Q6IQ16,P32121,P48729,P17252,Q13618 5
Gdnfret signaling axis 0.5079908675798981 0.2657049098660058 0.7904664817477807 1.0 0.998185071330168 3 O94813,P35222 2
Amyotrophic lateral sclerosis als 0.3863798201857749 0.254336436397728 0.7992356528807085 1.0 1.0 12 P07196,Q9BUN8 2
Interactions between loxl4 and oxidative stress pathway 0.4010847844704446 0.2161706997029315 0.8288546918304336 1.0 1.0 4 Q9BQ95,Q8TAG9,Q16543 3
Ppar signaling pathway 0.3590949897422918 0.2038024024424081 0.8385079153675234 1.0 1.0 17 O15254,P23786 2
Interleukin1 induced activation of nfkb 0.4758156510759732 0.1972296167386925 0.8436478549800328 1.0 1.0 3 P61088 1
G1 to s cell cycle control 0.3020130598468719 0.1949945826934414 0.8453971886057541 1.0 1.0 30 Q9Y619,Q14566 2
Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence 0.3642618650376034 0.1936900014621564 0.8464186212648803 1.0 1.0 15 P43490 1
Extracellular vesiclemediated signaling in recipient cells 0.4726027397260139 0.1910486981669876 0.8484874401381544 1.0 1.0 3 P35222,P42345 2
H19 action rbe2f1 signaling and cdkbetacatenin activity 0.3677898343803527 0.1652400579854722 0.8687550368925205 1.0 1.0 5 P11802,P35222,P06400,O75367 4
Type ii interferon signaling ifng 0.3508634824205604 0.1540203022035672 0.8775937277464849 1.0 1.0 6 Q03518 1
Type 2 papillary renal cell carcinoma 0.3520300851356349 0.1414064520580354 0.8875488574831252 1.0 1.0 8 P23246,P11166 2
Dna mismatch repair 0.32088898441893 0.1237827055706273 0.901487325447289 1.0 1.0 21 Q9UQ84 1
Nonhomologous end joining 0.353125892092491 0.1141075244961851 0.909152557501698 1.0 1.0 4 P78527,P13010,P12956 3
Myometrial relaxation and contraction pathways 0.3101695422611449 0.1022626231243004 0.9185482221551048 1.0 1.0 22 P78417,P16615,P19838,Q9UBI6,Q13555 5
Sting pathway in kawasakilike disease and covid19 0.3400958711787414 0.0926432088522045 0.9261870156360136 1.0 1.0 4 Q86UT6 1
Ptf1a related regulatory pathway 0.5552068473609187 0.0850193778262867 0.9322459852080812 1.0 1.0 2 P35222 1
Disruption of postsynaptic signaling by cnv 0.3299858313337998 0.0760653595441021 0.9393670993476472 1.0 1.0 9 Q14168,Q7L576,Q13555 3
Photodynamic therapyinduced hif1 survival signaling 0.333913945836582 0.0729338319804399 0.9418587715969882 1.0 1.0 12 P11166,Q07820,P53985 3
Kisspeptinkisspeptin receptor system in the ovary 0.3306627185868826 0.0714910587872861 0.9430069404052102 1.0 1.0 10 Q15118,P31751,P19838 3
Ciliopathies 0.3089251521034742 0.065800367694948 0.9475367634941814 1.0 1.0 21 O43924,Q9UBB4,P57076,Q13432 4
Mir124 predicted interactions with cell cycle and differentiation 0.5206847360913057 0.0590343823629224 0.9529247226905206 1.0 1.0 2 P26599 1
Cerebral organic acidurias including diseases 0.3139405321181496 0.0580249367388327 0.9537287653417956 1.0 1.0 5 P49419 1
Neural crest cell migration during development 0.3216263676185867 0.0489077645350758 0.9609928010648838 1.0 1.0 10 P31751 1
Neural crest cell migration in cancer 0.3228846768287047 0.0463037391899756 0.963068159065236 1.0 1.0 11 O75962,P31751 2
Robo4 and vegf signaling pathways crosstalk 0.3421803652967973 0.040285853054602 0.9678652322506291 1.0 1.0 3 O94813,P63000 2
Circadian rhythm genes 0.2686133772559412 0.0356289713142013 0.9715782072140284 1.0 1.0 46 P54802,O75376,P23246,P00813,Q8WXF1,P11802,P43490 7
T cell receptor and costimulatory signaling 0.3063918968525551 0.0324784407157547 0.9740905087746408 1.0 1.0 8 Q15118 1
Hippoyap signaling pathway 0.4522111269614924 0.0309562725633705 0.9753044123837756 1.0 1.0 2 Q13188 1
Somatroph axis gh and its relationship to dietary restriction and aging 0.4008559201141306 0.0229772384112591 0.98166842927207 1.0 1.0 2 P42345 1
Neural crest differentiation 0.3048423475212028 0.0200961362615766 0.9839666823407898 1.0 1.0 9 P19838,Q9NR77 2
Steroid biosynthesis 0.3229671897289669 0.0197943319633711 0.9842074394369608 1.0 1.0 2 P51659 1