Upload folder using huggingface_hub

interpro_active_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_active_site/basic/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:cdf7f7693bf3ca6f6547bf346f83d2dd6967d748b5f0fd73be86cfec6fbacf55
+size 77173

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3198,
+    "annotations_size": 54,
+    "title": "Average number of proteins per term",
+    "value": 2.611111111111111
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C091/C091_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Histidine acid phosphatase active site [IPR033379]	0.8917396745932411	1.4871027670955417	0.1369876708301167	0.9996493143381482	0.2739753416602335	2	Q9NPH0	1
+Serine carboxypeptidase, serine active site [IPR018202]	0.8544600938967105	1.2608431005386531	0.2073653817177319	0.9999964523239584	0.3499290816486726	3	Q9HB40,P10619	2
+Protein-tyrosine phosphatase, active site [IPR016130]	0.4138651688684824	0.1809414764764725	0.8564135126161969	1.0	0.9249265936254928	5	Q8WUK0,P18031	2

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "JAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MDH1", "MDH2", "MTMR14", "NCEH1", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRKCA", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "RIPK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UMPS", "VRK1", "VRK2"], "leading_proteins": ["ACP6", "CTSA", "PTPMT1", "PTPN1", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:05fe0f3b386f19bf36f336c19540b95473370cc8f11cdd823eea368bd197d6e8
+size 73994

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3198,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.483870967741935
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C091/C091_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.4134896409662342	1.4140477818266668	0.1573478735437394	0.9950443804980552	0.3921305490820602	36	Q9NWM8,Q14257,Q6NUK1,P43304,O75340,Q9BPX6,O43852,P80303,Q02818,Q9Y680,O95202	11
+Peptidase M16, zinc-binding site [IPR001431]	0.6749981930872296	1.2574108481497763	0.2086049030524974	0.9992917378818827	0.4041719996642138	5	Q10713	1
+Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]	0.7966207759699598	1.0840364075398423	0.2783486566426953	0.9999594351236586	0.430106920865285	2	P34897	1
+Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]	0.4899874843554301	0.1028367619480254	0.9180925281083157	1.0	0.9486956123785928	2	O15270	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "JAK1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK1", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKACA", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "FKBP14", "FKBP7", "GPD2", "LETM1", "MICU1", "NUCB1", "NUCB2", "PDCD6", "PMPCA", "RCN2", "SHMT2", "SLC25A24", "SPTLC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "ABC transporter-like, conserved site [IPR017871]", "1": "Short-chain dehydrogenase/reductase, conserved site [IPR020904]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:715c9e949be26909f0b4b287ea8d0f5b75f1269b4bf9dfd208fff56aa94c6483
+size 93723

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3198,
+    "annotations_size": 279,
+    "title": "Average number of proteins per term",
+    "value": 2.6594982078853047
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C091/C091_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,26 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Haem oxygenase conserved site [IPR018207]	0.9840425531914916	1.8786777735060385	0.0602885044848306	0.9999999707936992	0.2473601875186435	2	P09601	1
+Syntaxin/epimorphin, conserved site [IPR006012]	0.8042548712367908	1.828945248646072	0.0674078107557598	0.999999996500509	0.2562097110538396	5	Q9P2W9,O60499,O15400	3
+Tetraspanin, conserved site [IPR018503]	0.9583724569640008	1.6699036109067755	0.0949384358136906	0.9999999999991812	0.3116214540237611	3	O60637,O43657	2
+Thioredoxin, conserved site [IPR017937]	0.5981727022957047	1.603224996135648	0.1088849887665366	0.9999999999999892	0.3340319796590261	11	Q96JJ7,Q9H1E5,O43396	3
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.8086120256821978	1.6029327658432584	0.1089494987418329	0.9999999999999896	0.3340319796590261	4	Q8WWV3	1
+Sugar transporter, conserved site [IPR005829]	0.8623279098873593	1.361831535105384	0.1732510569473884	1.0	0.4099297952890273	2	Q7L0J3	1
+ABC transporter-like, conserved site [IPR017871]	0.5349793517461415	1.3294814075377126	0.1836891957810871	1.0	0.4166608587229537	12	Q9NUT2,P08183,P28288,O75027,O14678,Q03519	6
+Guanylate kinase, conserved site [IPR020590]	0.6853365758232165	1.3037802857682514	0.1923085061768952	1.0	0.4292325857868301	5	O14936,Q14168,Q9NZW5	3
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.8291614518147672	1.2210273073345452	0.22207568075347	1.0	0.453288683889604	2	P40939	1
+Sterol reductase, conserved site [IPR018083]	0.8272841051314235	1.213085186789229	0.2250972528830928	1.0	0.453288683889604	2	Q14739	1
+AMP-binding, conserved site [IPR020845]	0.6127222455481195	1.1725747976655232	0.240966360833474	1.0	0.4722324540521359	6	P33121,O95573,O14975	3
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.756883604505628	0.9196217996128868	0.357770430771946	1.0	0.6086460377156887	2	P11279	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.750938673341682	0.8954087317260313	0.3705686346833028	1.0	0.6207411582277853	2	Q9BTY2	1
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.4732796726107189	0.883691301320734	0.3768628773232034	1.0	0.6258615641260343	11	Q6IAN0,Q53GQ0,Q8NBN7,Q9Y394,Q06136	5
+DnaJ domain, conserved site [IPR018253]	0.4575342363853857	0.7922446437758763	0.4282180420864816	1.0	0.660070904652643	11	Q9Y2G8,Q96KC8	2
+Proteasome beta-type subunit, conserved site [IPR016050]	0.4760197385769091	0.7434431326318498	0.4572134386841444	1.0	0.6785241988982782	8	P20618,P28074,P28072,P49721	4
+Intermediate filament protein, conserved site [IPR018039]	0.4952096618419068	0.7186104716881988	0.4723809594752153	1.0	0.6952126502244409	7	P08670,Q16352,P02545,P07196	4
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.7021276595744621	0.7020438628543694	0.4826518095488159	1.0	0.700568696179801	2	P04439	1
+Chromo domain, conserved site [IPR023779]	0.5133103664265705	0.5461784878293291	0.584943251934563	1.0	0.7648744060022838	5	Q14781,P45973,O14646,Q13185	4
+Clathrin adaptor complex, small chain [IPR000804]	0.6510172143974942	0.4995013371532723	0.6174262450103121	1.0	0.7763450425208491	3	P61923,P53680	2
+Dynamin, GTPase region, conserved site [IPR019762]	0.6257822277847318	0.4293908142381375	0.6676388375020672	1.0	0.7852687541840697	2	P50570	1
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.6109395310822489	0.3725515241304735	0.7094822575198572	1.0	0.8134992220488029	3	Q5T8D3	1
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.5162703379223901	0.14641672682199	0.883592423512964	1.0	0.9481626390773727	2	P82675	1
+RNA polymerase, beta subunit, conserved site [IPR007121]	0.4452440550688202	0.0501010661734587	0.9600418501234136	1.0	0.988382568946245	2	Q9H9Y6	1
+Mrp, conserved site [IPR000808]	0.4219092331768486	0.0083939679715578	0.9933026611993416	1.0	1.0	3	Q9Y5Y2,Q8TB37	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Connexin, conserved site [IPR017990]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GJA1", "GLA", "GLB1", "GLO1", "GMPPA", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "ING5", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NUBP1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RBFA", "RCL1", "RDH13", "RDX", "RIDA", "RNF2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAP", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC2A4", "SLC4A2", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STRN4", "STX10", "STX12", "STX18", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAF5", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM13", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP34", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ACBD5", "ACSL1", "ACSL3", "AP2S1", "CASK", "CBX2", "CBX3", "CBX5", "CHD1", "COPZ1", "DHRS7", "DHRS7B", "DNAJC1", "DNAJC16", "DNM2", "FUCA2", "HADHA", "HLA-A", "HMOX1", "HSD17B12", "INA", "KDSR", "LAMP1", "LBR", "LMNA", "MPP2", "MPP6", "MRPS5", "NEFL", "NUBP2", "NUBPL", "POLR1B", "PSMB1", "PSMB2", "PSMB5", "PSMB6", "RDH13", "RTN4IP1", "SLC27A2", "STX10", "STX18", "STX7", "SV2A", "TAP2", "TMX3", "TMX4", "TSPAN3", "TSPAN6", "TXNL1", "VIM"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "1": "Phospholipid/glycerol acyltransferase [IPR002123]", "2": "GOLD domain [IPR009038]", "3": "ABC transporter type 1, transmembrane domain [IPR011527]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "1": "Phospholipid/glycerol acyltransferase [IPR002123]", "2": "GOLD domain [IPR009038]", "3": "ABC transporter type 1, transmembrane domain [IPR011527]", "4": "EF-hand domain [IPR002048]", "5": "ABC transporter-like, ATP-binding domain [IPR003439]", "6": "Thioredoxin domain [IPR013766]", "7": "AP complex, mu/sigma subunit [IPR022775]", "8": "DnaJ domain [IPR001623]", "9": "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:fdc2849af5f3a38a4444c7fdc0a7ceb21fdb5a5fdce6d8ca06742b8ff59ae8ad
+size 266533

interpro_domain/df_merge.tsv

@@ -0,0 +1,9 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	5	7	2.520105616813495	0.0117319626133707	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.0001451706848618	1.0	0.1898352204968973	0.0963497504158291	0.0004660922169925
+Phospholipid/glycerol acyltransferase [IPR002123]	6	8	2.4510298827631924	0.0142448126853256	2.4611650485436893	6.109223300970874	0.4541526786138767	0.3733328307275969	1.647577392422315	1.6678607828333205	1.200305691546449	0.3080828121567173	0.0223420124551985	0.0727733471903131	0.1419203898220533	0.3214791435692521	0.0007120067884844
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	4	5	2.1820844324725304	0.0291033019172386	2.2985436893203883	4.150485436893204	0.5310155053290574	0.3897464493012307	1.1928988171245156	0.7984662222288074	1.1360507856968378	0.3059467081218019	1.848021335060864e-05	1.0	1.0	0.2152011075186096	5.228222212650434e-05
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	4	5	2.1820844324725304	0.0291033019172386	2.2985436893203883	4.150485436893204	0.5310155053290574	0.3897464493012307	1.1928988171245156	0.7984662222288074	1.1360507856968378	0.3059467081218019	1.848021335060864e-05	1.0	1.0	0.2152011075186096	5.228222212650434e-05
+LEM domain [IPR003887]	2	6	2.1190227221455435	0.0340885467221399	2.237864077669903	5.759708737864078	0.8787481060627674	0.3228260833428172	1.2758866328838632	0.4653299410110203	1.033781091163317	0.2887768895441466	0.0010653692918622	1.0	1.0	0.0002566819155387	0.0019903460540529
+GOLD domain [IPR009038]	5	7	2.0830941203780258	0.037242645217081	2.8762135922330097	6.247572815533981	0.4192390492462461	0.3068843884052658	1.4199402534298398	0.930533270242389	1.3963570929114475	0.294203492723015	0.0012119796208221	1.0	1.0	0.2702644522094949	0.0002366253635482
+ABC transporter type 1, transmembrane domain [IPR011527]	6	8	2.0620679124254058	0.0392012707634761	2.3689320388349513	6.349514563106796	0.6640264147492347	0.3307390797434538	1.7803691733569	2.1393617497725477	1.1694677427725269	0.279101120079799	0.1133016596943162	1.0	1.0	0.3048182711761639	0.004742585973098
+Ricin B, lectin domain [IPR000772]	2	6	1.9815208362664545	0.0475328950689706	1.4174757281553398	4.121359223300971	0.4009585995426035	0.4855340701643459	1.119329478938434	0.8894364404712861	0.9609441077042546	0.3172385378622441	0.0186802058739128	1.0	1.0	0.048794410492492	0.0327721806990011

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3198,
+    "annotations_size": 2586,
+    "title": "Average number of proteins per term",
+    "value": 2.1759474091260635
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C091/C091_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,180 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.8706494057622829	2.520105616813495	0.0117319626133707	0.9999999999999444	0.1798574393521486	7	P16615,P20020,Q9HD20,P98194,P05023	5
+Phospholipid/glycerol acyltransferase [IPR002123]	0.8118241829608803	2.4510298827631924	0.0142448126853256	1.0	0.1816281088249048	8	Q9HCL2,Q8NF37,Q92604,Q86UL3,Q6UWP7,O15228	6
+Reticulon [IPR003388]	0.9539762053850918	2.1993635079580547	0.0278520852481765	1.0	0.211318553581944	4	Q9NQC3,O95197,O75298	3
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.8872533667397445	2.1820844324725304	0.0291033019172386	1.0	0.211318553581944	5	P05023,P20020,P16615,P98194	4
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.8872533667397445	2.1820844324725304	0.0291033019172386	1.0	0.211318553581944	5	P05023,P20020,P16615,P98194	4
+LEM domain [IPR003887]	0.8171560464222523	2.1190227221455435	0.0340885467221399	1.0	0.223738532546837	6	Q86XL3,P42167	2
+GOLD domain [IPR009038]	0.7740702561941236	2.0830941203780258	0.037242645217081	1.0	0.2271450012532351	7	Q9Y3B3,P49755,Q9BVK6,Q9Y3A6,Q15363	5
+ABC transporter type 1, transmembrane domain [IPR011527]	0.7307420858929501	2.0620679124254058	0.0392012707634761	1.0	0.2335817654247678	8	Q9NUT2,P08183,P28288,O75027,O14678,Q03519	6
+Ricin B, lectin domain [IPR000772]	0.7863525942040177	1.9815208362664545	0.0475328950689706	1.0	0.2600256971074206	6	Q9UBG0,Q10472	2
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.7719518434149041	1.9165352366520776	0.0552970025225934	1.0	0.273942621692388	6	O00264,O15173,O43169	3
+Prenylcysteine lyase [IPR010795]	0.947121401752196	1.7226446469297274	0.0849528059110436	1.0	0.3289603048669922	2	Q9UHG3	1
+Major facilitator superfamily domain [IPR020846]	0.8371947401377585	1.722521720049286	0.0849750516825795	1.0	0.3289603048669922	4	P14672,Q7L0J3,Q9H2V7	3
+Peptidase S54, rhomboid domain [IPR022764]	0.9327284105131408	1.6615561566723804	0.0966018003615012	1.0	0.352141931290625	2	Q6NTF9	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.7131886712092341	1.6469197330653202	0.0995745452997522	1.0	0.3567996325546307	6	Q9NZ08,Q9UIQ6,P55786	3
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.7131886712092341	1.6469197330653202	0.0995745452997522	1.0	0.3567996325546307	6	Q9NZ08,Q9UIQ6,P55786	3
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.950547730829416	1.6392523818707283	0.1011607086678139	1.0	0.3573844388778797	3	Q15629,Q96G23	2
+Fatty acid hydroxylase [IPR006694]	0.915832290362964	1.5897082930128186	0.1119005734980826	1.0	0.3777739987807335	2	Q15800	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.9117647058823604	1.572394871640394	0.1158590028874093	1.0	0.381237250635039	2	Q8N2A8	1
+BRICHOS domain [IPR007084]	0.9064455569461828	1.549746883690574	0.1212022803932533	1.0	0.3864723761984625	2	Q9Y287	1
+N-acetylgalactosaminyltransferase [IPR045885]	0.7923715696602223	1.5345814849388129	0.1248866634970398	1.0	0.3886364762976473	4	Q10472	1
+Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]	0.8864205256570719	1.464439533490112	0.1430738930061816	1.0	0.4169581410631219	2	P20020	1
+Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]	0.8839173967459483	1.4537746185314762	0.14600880258879	1.0	0.4209350763596555	2	Q9HCL2	1
+GPAT/DHAPAT, acyltransferase domain [IPR041728]	0.8839173967459483	1.4537746185314762	0.14600880258879	1.0	0.4209350763596555	2	Q9HCL2	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.8817271589486848	1.444443136083139	0.1486143642519475	1.0	0.4248328314718965	2	P13674	1
+Glycosyl transferase, family 1 [IPR001296]	0.8811013767209132	1.4417770757428632	0.1493652719304754	1.0	0.4258639395944978	2	Q9BT22	1
+Amino acid transporter, transmembrane domain [IPR013057]	0.8785982478097614	1.4311132825596258	0.1523977511165442	1.0	0.4312670013787237	2	Q96QD8	1
+Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]	0.874843554443053	1.4151193476331358	0.1570335063867012	1.0	0.4371244860236914	2	Q8NF37	1
+Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]	0.8895148669796431	1.3990873914619528	0.1617867782126234	1.0	0.4431997970951739	3	Q96RQ1,Q9Y282	2
+Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]	0.8895148669796431	1.3990873914619528	0.1617867782126234	1.0	0.4431997970951739	3	Q96RQ1,Q9Y282	2
+ERAP1-like C-terminal domain [IPR024571]	0.7601753287413744	1.398388609343647	0.1619964018371891	1.0	0.4433044393131969	4	P55786,Q9UIQ6,Q9NZ08	3
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.8642052565707117	1.3698214395387531	0.1707426477867497	1.0	0.4547275872054942	2	Q15067	1
+EF-hand domain [IPR002048]	0.4149810646234076	1.3524008202457776	0.1762471271802421	1.0	0.4610279324009785	44	Q9NWM8,Q14257,Q6NUK1,P43304,Q8NF37,O75340,Q9BPX6,O75071,O43852,P80303,Q02818,Q9Y680,O95202	13
+Glycosyltransferase 2-like [IPR001173]	0.6494186807242823	1.3472904241568076	0.1778867149556204	1.0	0.4623266782665674	6	Q8N4A0,Q9Y673,Q10472	3
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.8579474342928836	1.3431942296420023	0.1792090896483316	1.0	0.4625096864576701	2	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.8579474342928836	1.3431942296420023	0.1792090896483316	1.0	0.4625096864576701	2	Q13505	1
+Fibronectin type II domain [IPR000562]	0.8729770239530926	1.3338495830649055	0.1822531574130916	1.0	0.4666402624457971	3	Q9UBG0	1
+Sterol-sensing domain [IPR000731]	0.8726134585289402	1.3324155187461817	0.1827236853750833	1.0	0.4670799019566286	3	P04035,O15118	2
+ABC transporter-like, ATP-binding domain [IPR003439]	0.5349793517461415	1.3294814075377126	0.1836891957810871	1.0	0.4670799019566286	12	Q9NUT2,P08183,P28288,O75027,O14678,Q03519	6
+SUN coiled coil domain 2 [IPR040994]	0.851376720901136	1.3152562677110846	0.1884237903457197	1.0	0.4707609203140213	2	O94901	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8494993742177712	1.3072785855779785	0.1911181143316218	1.0	0.4724966000588662	2	Q9NVI7	1
+Thioredoxin domain [IPR013766]	0.4264358084407172	1.245451104144625	0.2129659782027058	1.0	0.503085635457248	26	Q96JJ7,Q96J42,Q9H1E5,O43396,Q9H3N1,Q6ZRP7,Q9Y320	7
+L27 domain [IPR004172]	0.719805341464525	1.226830773278634	0.2198862019767382	1.0	0.507785550671774	4	O14936,Q9NZW5	2
+L27 domain, C-terminal [IPR014775]	0.719805341464525	1.226830773278634	0.2198862019767382	1.0	0.507785550671774	4	O14936,Q9NZW5	2
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.8291614518147672	1.2210273073345452	0.22207568075347	1.0	0.5082192127685607	2	P40939	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.8291614518147672	1.2210273073345452	0.22207568075347	1.0	0.5082192127685607	2	P40939	1
+Bicarbonate transporter, C-terminal [IPR011531]	0.822277847309135	1.1919258085839617	0.2332903374472299	1.0	0.5191678826841182	2	Q9Y6M7	1
+Band 3 cytoplasmic domain [IPR013769]	0.822277847309135	1.1919258085839617	0.2332903374472299	1.0	0.5191678826841182	2	Q9Y6M7	1
+Peptidase M16, C-terminal [IPR007863]	0.5900194279055606	1.191315305207543	0.2335298276962656	1.0	0.5191678826841182	7	Q10713	1
+Peptidase M16, N-terminal [IPR011765]	0.5900194279055606	1.191315305207543	0.2335298276962656	1.0	0.5191678826841182	7	Q10713	1
+G-protein gamma-like domain [IPR015898]	0.8153942428035195	1.1628826823489988	0.2448771045562057	1.0	0.5325601333830866	2	P63218	1
+Tim10-like [IPR004217]	0.7014996690526485	1.1489938065959753	0.2505585344966099	1.0	0.5386712955545376	4	Q9Y5J6,P62072	2
+Tim44-like domain [IPR007379]	0.8019399249061393	1.106315958359496	0.2685897868908715	1.0	0.5594163130638146	2	O43615	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.8140845070422442	1.1022465221607531	0.2703545116488306	1.0	0.5594163130638146	3	O15460,P13674	2
+Serine hydroxymethyltransferase-like domain [IPR039429]	0.7966207759699598	1.0840364075398423	0.2783486566426953	1.0	0.5641431444173747	2	P34897	1
+Acyltransferase, C-terminal domain [IPR032098]	0.8090872011963657	1.082715910616615	0.2789345396425402	1.0	0.5648588249926461	3	Q92604	1
+FAD/NAD(P)-binding domain [IPR023753]	0.5934584330924892	1.080568436176523	0.279889129267453	1.0	0.5663484258886021	6	Q9Y6N5	1
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.6317263189156309	1.0630813687698055	0.2877450527806287	1.0	0.5754901055612573	5	Q8WWV3	1
+FAD linked oxidase, N-terminal [IPR006094]	0.7866082603254246	1.0422483797373443	0.2972965381150345	1.0	0.585982353327347	2	Q15392	1
+FAD-binding domain, PCMH-type [IPR016166]	0.7866082603254246	1.0422483797373443	0.2972965381150345	1.0	0.585982353327347	2	Q15392	1
+Band 7 domain [IPR001107]	0.5309265372803769	1.0333738640040535	0.3014289726392083	1.0	0.590797763887265	8	P27105,P35232,Q99623,O75955	4
+CNNM, transmembrane domain [IPR002550]	0.7812891113892335	1.0201365647236724	0.3076636975374014	1.0	0.5945272892518181	2	Q8NE01	1
+Ion transporter-like, CBS domain [IPR044751]	0.7812891113892335	1.0201365647236724	0.3076636975374014	1.0	0.5945272892518181	2	Q8NE01	1
+Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]	0.7784730913642022	1.0084572161312388	0.3132350170637932	1.0	0.5979425802447216	2	Q9UHQ9	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.5486594969600508	0.9841833057832092	0.3250253925370256	1.0	0.6095109971724063	7	O60313,O95140,Q8IWA4	3
+Dynamin, N-terminal [IPR045063]	0.5486594969600508	0.9841833057832092	0.3250253925370256	1.0	0.6095109971724063	7	O60313,O95140,Q8IWA4	3
+Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]	0.7787167449139254	0.9647747537704492	0.3346576436691451	1.0	0.6122454694251575	3	Q9UHQ9,P16435	2
+Oxidoreductase FAD/NAD(P)-binding [IPR001433]	0.7787167449139254	0.9647747537704492	0.3346576436691451	1.0	0.6122454694251575	3	Q9UHQ9,P16435	2
+FAD-binding domain, ferredoxin reductase-type [IPR017927]	0.7787167449139254	0.9647747537704492	0.3346576436691451	1.0	0.6122454694251575	3	Q9UHQ9,P16435	2
+Fzo/mitofusin HR2 domain [IPR006884]	0.7634543178973918	0.9465161749295332	0.3438853762302183	1.0	0.6162769112483331	2	Q8IWA4	1
+NOPS [IPR012975]	0.7693270735524291	0.92864064717298	0.353075349351172	1.0	0.6258073018657511	3	Q15233,Q8WXF1	2
+Target SNARE coiled-coil homology domain [IPR000727]	0.5322301017787552	0.90204070175278	0.3670352468563771	1.0	0.6380131424176982	7	O15400,O60499,Q9UNK0	3
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.750938673341682	0.8954087317260313	0.3705686346833028	1.0	0.6380131424176982	2	Q9BTY2	1
+SLC12A transporter, C-terminal [IPR018491]	0.748435544430534	0.8852498782286102	0.3760218762310647	1.0	0.640153108580338	2	Q9BXP2	1
+Amino acid permease/ SLC12A domain [IPR004841]	0.748435544430534	0.8852498782286102	0.3760218762310647	1.0	0.640153108580338	2	Q9BXP2	1
+CARG-binding factor, N-terminal [IPR012956]	0.7481226533166416	0.8839815773103672	0.3767061578551067	1.0	0.6408961343508592	2	Q99729	1
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.6365577930226716	0.8750436606241885	0.3815501499767166	1.0	0.6451493483568262	4	P33121,O14975	2
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.5414416022822041	0.8330371071637791	0.4048238018913412	1.0	0.6646423293227777	6	O15460,P13674	2
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.5414416022822041	0.8330371071637791	0.4048238018913412	1.0	0.6646423293227777	6	O15460,P13674	2
+Stromal interaction molecule, Orai1-activating region [IPR032393]	0.7324780976220309	0.8210387476011867	0.4116241977328663	1.0	0.668630763402759	2	Q13586	1
+Zinc finger, CHHC-type [IPR012996]	0.7376608708619072	0.8083601808886667	0.4188832675330887	1.0	0.6718696821303738	3	P31943	1
+Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]	0.7199624530663491	0.7714227991043556	0.4404563656161033	1.0	0.6886458050080069	2	Q15418	1
+v-SNARE, coiled-coil homology domain [IPR042855]	0.7265017235650852	0.7666866336729167	0.4432678525875064	1.0	0.6905365462598142	3	O15498	1
+Longin domain [IPR010908]	0.7265017235650852	0.7666866336729167	0.4432678525875064	1.0	0.6905365462598142	3	O15498	1
+Man1/Src1, C-terminal [IPR018996]	0.7143304130162647	0.7493356327219262	0.4536549361410094	1.0	0.6966458817462294	2	Q8NC56	1
+BSD domain [IPR005607]	0.7115143929912334	0.7383518448323366	0.4603006692132763	1.0	0.7014363763026119	2	Q96A49	1
+Choline/carnitine acyltransferase domain [IPR039551]	0.7151802835060745	0.7248673843397693	0.4685333916977328	1.0	0.706156366577856	3	P23786	1
+Exosome complex component, N-terminal domain [IPR025721]	0.7071339173967401	0.7213484809464626	0.4706951356151956	1.0	0.7080963471209399	2	Q9Y3B2	1
+Intermediate filament, rod domain [IPR039008]	0.4952096618419068	0.7186104716881988	0.4723809594752153	1.0	0.7098066015124386	7	P08670,Q16352,P02545,P07196	4
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.7015018773466772	0.6996406687603184	0.4841517378521545	1.0	0.7199634238560504	2	O43390	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.702347417840367	0.6780962395562861	0.4977106748756572	1.0	0.726365772722024	3	P10321,P04439	2
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.702347417840367	0.6780962395562861	0.4977106748756572	1.0	0.726365772722024	3	P10321,P04439	2
+Immunoglobulin C1-set [IPR003597]	0.702347417840367	0.6780962395562861	0.4977106748756572	1.0	0.726365772722024	3	P10321,P04439	2
+MHC class I-like antigen recognition-like [IPR011161]	0.702347417840367	0.6780962395562861	0.4977106748756572	1.0	0.726365772722024	3	P10321,P04439	2
+Potentiating neddylation domain [IPR005176]	0.6931827171150675	0.6451503960919611	0.518829727850664	1.0	0.7337879231855136	3	Q92564	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.6858573216520585	0.6403217417434162	0.5219634487245399	1.0	0.7351332605369442	2	P98179	1
+Immunoglobulin-like domain [IPR007110]	0.3929317064346307	0.6378950879852371	0.5235419754713728	1.0	0.7358041024831359	15	Q08722,P15151,P10321,P35613	4
+Lamin tail domain [IPR001322]	0.6904538341158052	0.6354195896221105	0.5251547950632751	1.0	0.736869397739354	3	P02545,Q03252	2
+Guanylate kinase-like domain [IPR008144]	0.4763548658116662	0.6268240017161655	0.5307746085278611	1.0	0.7409547367391085	7	O14936,Q14168,Q9NZW5	3
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.4763548658116662	0.6268240017161655	0.5307746085278611	1.0	0.7409547367391085	7	O14936,Q14168,Q9NZW5	3
+AP complex, mu/sigma subunit [IPR022775]	0.4965538847117888	0.6240798948767644	0.5325751168590906	1.0	0.7409547367391085	6	P61923,P53680,Q9Y2T2,Q96CW1,Q92572	5
+Syntaxin, N-terminal domain [IPR006011]	0.6811639549437019	0.6228293154211737	0.5333966917299524	1.0	0.7409547367391085	2	O15400	1
+Dynamin, GTPase domain [IPR001401]	0.684040862326734	0.6127027479259852	0.5400729052305566	1.0	0.7456001395392177	3	O60313	1
+Major sperm protein (MSP) domain [IPR000535]	0.6823161189358427	0.6066304193682559	0.5440962080386311	1.0	0.7476836028829502	3	Q9P0L0,Q8NHP6	2
+Extended PHD (ePHD) domain [IPR034732]	0.6764705882353002	0.6054869701863397	0.5448554796850462	1.0	0.747874878166417	2	Q03164	1
+Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]	0.6686483103879777	0.5769324909157226	0.5639850609067207	1.0	0.7525621091355934	2	Q15118	1
+Histidine kinase domain [IPR005467]	0.6686483103879777	0.5769324909157226	0.5639850609067207	1.0	0.7525621091355934	2	Q15118	1
+PSI domain [IPR016201]	0.664893617021269	0.5633882787575183	0.5731705169236836	1.0	0.7583000849680763	2	O15031	1
+SUN domain [IPR012919]	0.6674087612313739	0.5548485983865051	0.5789982228268	1.0	0.7591841606466826	3	O94901	1
+Tudor domain [IPR002999]	0.4755905529989401	0.5295651795647485	0.5964134419402263	1.0	0.7653167898702973	6	Q14739,Q9Y2W6	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.659677606183104	0.5285238736521959	0.597135781583858	1.0	0.7653167898702973	3	P61289	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.659677606183104	0.5285238736521959	0.597135781583858	1.0	0.7653167898702973	3	P61289	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.5463099783220099	0.5139445197313283	0.6072907802735406	1.0	0.7719566011433201	4	P08670,P07196	2
+EF hand associated, type-1 [IPR013566]	0.6414267834793408	0.4813371888415492	0.6302768701354053	1.0	0.778012598297589	2	Q8IXI2	1
+MIRO domain [IPR020860]	0.6414267834793408	0.4813371888415492	0.6302768701354053	1.0	0.778012598297589	2	Q8IXI2	1
+EF hand associated, type-2 [IPR013567]	0.6414267834793408	0.4813371888415492	0.6302768701354053	1.0	0.778012598297589	2	Q8IXI2	1
+PB1 domain [IPR000270]	0.6401752190237728	0.4770958809376699	0.6332938476760221	1.0	0.778012598297589	2	Q92734	1
+AMP-dependent synthetase/ligase [IPR000873]	0.4421014774036345	0.4649913941844987	0.641937619425824	1.0	0.7812003218047909	7	P33121,O95573,O14975	3
+IMD/I-BAR domain [IPR013606]	0.6357947434292998	0.4623660255981359	0.6438188587016596	1.0	0.7823851356214716	2	Q9UQB8	1
+Legume-like lectin [IPR005052]	0.6381846635367597	0.4574710402782701	0.6473325130074892	1.0	0.7829349254282406	3	P49257,Q9H0V9	2
+Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]	0.6273466833541839	0.4344779114305155	0.6639414314933922	1.0	0.7924922772504999	2	Q8TBX8	1
+GTPase effector domain [IPR020850]	0.6257822277847318	0.4293908142381375	0.6676388375020672	1.0	0.7937129971091117	2	P50570	1
+Dynamin GTPase effector [IPR003130]	0.6257822277847318	0.4293908142381375	0.6676388375020672	1.0	0.7937129971091117	2	P50570	1
+Dynamin stalk domain [IPR000375]	0.6257822277847318	0.4293908142381375	0.6676388375020672	1.0	0.7937129971091117	2	P50570	1
+Amine oxidase [IPR002937]	0.6252527985417096	0.4163907855954638	0.6771240699634007	1.0	0.7958600660452587	3	Q8NB78	1
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.5187418700166788	0.4130789085822953	0.6795488016519646	1.0	0.7958600660452587	4	P21912	1
+Bms1/Tsr1-type G domain [IPR030387]	0.6201501877346591	0.4112838628373463	0.6808644009408542	1.0	0.7958600660452587	2	Q14692	1
+AARP2CN [IPR012948]	0.6201501877346591	0.4112838628373463	0.6808644009408542	1.0	0.7958600660452587	2	Q14692	1
+Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]	0.6201501877346591	0.4112838628373463	0.6808644009408542	1.0	0.7958600660452587	2	Q14692	1
+Class II aldolase/adducin N-terminal [IPR001303]	0.6160826032540583	0.398412189096414	0.6903263744395687	1.0	0.8004674710287478	2	Q9UEY8	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.6159624413145518	0.3877318448019652	0.6982144870539684	1.0	0.806063689072126	3	A0FGR8,Q8IWB9	2
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.6107634543178879	0.3818476103349876	0.7025744017901154	1.0	0.8085702728212009	2	P51116	1
+DnaJ domain [IPR001623]	0.3421383514467501	0.3772281478083346	0.7060040639050882	1.0	0.8099940147553496	19	Q9Y2G8,Q96DA6,Q9NVH1,Q96KC8,Q9UGP8	5
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.6109395310822489	0.3725515241304735	0.7094822575198572	1.0	0.8118235035160843	3	Q5T8D3	1
+Alpha/beta hydrolase fold-1 [IPR000073]	0.4301689973001156	0.3360758434507824	0.7368136741733622	1.0	0.8250460652392012	6	P07099,P34913	2
+Mu homology domain [IPR028565]	0.4962429555416371	0.3357552026169275	0.737055474097223	1.0	0.8250460652392012	4	Q9BXS5,Q9Y2T2,Q96CW1	3
+YTH domain [IPR007275]	0.591051314142668	0.3232448433090085	0.7465098221521798	1.0	0.8310264313756078	2	Q7Z739	1
+Protein kinase, C-terminal [IPR017892]	0.4046892829290591	0.2995089528908244	0.7645517419658086	1.0	0.8420762991090702	7	Q15418	1
+Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]	0.3846992664707728	0.2913817169352078	0.7707593959693162	1.0	0.8463294408480689	8	Q9H5K3	1
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.5794743429286502	0.2909931992906481	0.7710565207417055	1.0	0.8463294408480689	2	Q9NUQ9	1
+Cobalamin (vitamin B12)-binding domain [IPR006158]	0.5754067584480491	0.2800614314633313	0.7794303743020383	1.0	0.8515449716709215	2	P22033	1
+AGC-kinase, C-terminal [IPR000961]	0.3808562058791723	0.2741518968325447	0.7839678930799585	1.0	0.8557792197149737	8	Q15418	1
+VHS domain [IPR002014]	0.5669586983729549	0.2580412865446712	0.7963750438259518	1.0	0.8674403733932917	2	O14964	1
+Peptidase M28 [IPR007484]	0.5618110370511984	0.2371456856284749	0.8125437710310475	1.0	0.8755159132859537	3	Q969V3	1
+Ribosomal protein S7 domain [IPR023798]	0.5528785982478008	0.2234520350869888	0.8231837097812222	1.0	0.8836666971748612	2	Q9Y2R9	1
+NAD-dependent epimerase/dehydratase [IPR001509]	0.5539906103286462	0.2179990909126057	0.8274298197400669	1.0	0.8863850513039822	3	Q13630,Q9NRG7	2
+CBS domain [IPR000644]	0.3817193030517519	0.2063441198326855	0.8365221173471309	1.0	0.8927966138917377	7	P51790,Q8NE01	2
+CTLH, C-terminal LisH motif [IPR006595]	0.5359824780976097	0.1855446122763629	0.8528018921495681	1.0	0.9064306177964584	2	Q2TAY7	1
+Hemimethylated DNA-binding domain [IPR011722]	0.5281602002503003	0.1693555463600818	0.8655169872294048	1.0	0.9158047990897058	2	O94952	1
+Methyltransferase type 11 [IPR013216]	0.5298871785513034	0.1635683823523722	0.8700709366485349	1.0	0.9198705814280912	3	Q6UX53	1
+Ribosomal protein S5, N-terminal [IPR013810]	0.5162703379223901	0.14641672682199	0.883592423512964	1.0	0.9307413471301528	2	P82675	1
+Ribosomal protein S5, C-terminal [IPR005324]	0.5162703379223901	0.14641672682199	0.883592423512964	1.0	0.9307413471301528	2	P82675	1
+Chromo domain subgroup [IPR017984]	0.5129890453834202	0.1296934073158456	0.8968089987131218	1.0	0.9404493392831036	3	P45973,Q13185	2
+Chromo shadow domain [IPR008251]	0.5129890453834202	0.1296934073158456	0.8968089987131218	1.0	0.9404493392831036	3	P45973,Q13185	2
+Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]	0.5123630672926536	0.1285079120899158	0.8977470371991547	1.0	0.9406701127216428	3	Q1KMD3,Q9BUJ2	2
+Exportin-1/Importin-beta-like [IPR013598]	0.4232936756418229	0.1262683698708833	0.8995194930140951	1.0	0.941764133171842	4	O14980,Q9HAV4,Q9Y5L0	3
+Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]	0.5031289111389111	0.1234075536698557	0.9017843758338768	1.0	0.9422280387500628	2	Q96GW9	1
+Methioninyl-tRNA synthetase core domain [IPR033911]	0.5031289111389111	0.1234075536698557	0.9017843758338768	1.0	0.9422280387500628	2	Q96GW9	1
+Methionyl/Leucyl tRNA synthetase [IPR015413]	0.5031289111389111	0.1234075536698557	0.9017843758338768	1.0	0.9422280387500628	2	Q96GW9	1
+UBX domain [IPR001012]	0.4159388664662393	0.1092990768054257	0.9129652788122684	1.0	0.9492171957578522	4	Q96CS3	1
+Peptidase M41 [IPR000642]	0.4940550688360315	0.108946008362864	0.9132453144027596	1.0	0.9492171957578522	2	Q9Y4W6	1
+Glutathione S-transferase, N-terminal [IPR004045]	0.3398329043297323	0.1053302946765549	0.916113724998149	1.0	0.9511116168883792	8	Q9H7Z7	1
+EF-hand, Ca insensitive [IPR014837]	0.4985915492957838	0.1036913019084688	0.9174143295165372	1.0	0.9512563978066422	3	P12814,O43707	2
+Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]	0.4796620775969817	0.0883502160423947	0.9295983283339712	1.0	0.9604240020262284	2	Q9H4A4	1
+Ribosomal protein L10e/L16 [IPR016180]	0.4759073842302755	0.0834399965288472	0.93350168674568	1.0	0.963302219443068	2	P27635	1
+Death domain [IPR000488]	0.4841940532081473	0.0803339600615772	0.9359716492622197	1.0	0.9654528140452884	3	Q12955,Q13546	2
+MRG domain [IPR026541]	0.4730913642052501	0.0798803383904319	0.9363324275427622	1.0	0.9654528140452884	2	Q9UBU8	1
+RNA polymerase Rpb2, domain 7 [IPR007641]	0.4452440550688202	0.0501010661734587	0.9600418501234136	1.0	0.9836244946193136	2	Q9H9Y6	1
+DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]	0.4452440550688202	0.0501010661734587	0.9600418501234136	1.0	0.9836244946193136	2	Q9H9Y6	1
+RNA polymerase Rpb2, domain 3 [IPR007645]	0.4452440550688202	0.0501010661734587	0.9600418501234136	1.0	0.9836244946193136	2	Q9H9Y6	1
+RNA polymerase Rpb2, domain 2 [IPR007642]	0.4452440550688202	0.0501010661734587	0.9600418501234136	1.0	0.9836244946193136	2	Q9H9Y6	1
+RNA polymerase, beta subunit, protrusion [IPR007644]	0.4452440550688202	0.0501010661734587	0.9600418501234136	1.0	0.9836244946193136	2	Q9H9Y6	1
+ZU5 domain [IPR000906]	0.4430538172715784	0.0481550281560283	0.9615926909105844	1.0	0.9846600812043336	2	Q12955	1
+Ribosomal protein S10 domain [IPR027486]	0.4414893617021136	0.0467983104300137	0.9626739756413968	1.0	0.9846600812043336	2	P60866	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.3350047007207786	0.0442943656392964	0.964669762836974	1.0	0.986022137034156	7	O00303,O00487,Q7L5N1,Q92905,O15372,Q6P2Q9	6
+Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]	0.4336670838548022	0.040420703558629	0.967757724683141	1.0	0.9865560261305504	2	Q96HY7	1
+Dbl homology (DH) domain [IPR000219]	0.3810269254852784	0.04029200709836	0.967860326017638	1.0	0.9865560261305504	4	Q92974,Q6XZF7,Q14155	3
+Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]	0.4327284105131322	0.0396997979913488	0.9683324627309408	1.0	0.9866460790473652	2	Q9Y305	1
+Dehydrogenase, E1 component [IPR001017]	0.4338028169014188	0.0187087914293678	0.9850734149367286	1.0	1.0	3	Q96HY7,P08559	2
+Survival motor neuron [IPR010304]	0.3144555694618171	0.0008890950776597	0.9992906048579112	1.0	1.0	2	Q16637	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "P-type ATPase [IPR001757]", "2": "Short-chain dehydrogenase/reductase SDR [IPR002347]"}