diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..5eed6ae452d4071d874ea6600ea6d3605d191637 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e1b4c0ae4996a701816440cb819a9eddd1f99c8f27192aa307d6729be74bd991 +size 81693 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9b15c40ac83089ab86875ae8e14985b198859e92 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 54, + "title": "Average number of proteins per term", + "value": 2.611111111111111 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ca0037914b0b676ac502203614f8286bb6f0b1d7 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f5f5c83c81cfa1bf2b6e57359aafafeaac8d49d8 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Histidine acid phosphatase active site [IPR033379] 0.8654568210262927 1.798302158291748 0.0721291379142177 0.982447984777595 0.1256981152405043 2 Q9NPH0 1 +Serine carboxypeptidase, serine active site [IPR018202] 0.7021279122808483 0.816211596756118 0.4143791252902673 0.9999999999997172 0.5434175764342777 3 P10619 1 +Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999] 0.5164319248826356 0.2032423363083622 0.838945623721755 1.0 0.9060612736194954 3 Q16881,P00390 2 +Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345] 0.4152065081351518 0.0891023334455699 0.9290005829517364 1.0 0.9836476760665446 2 Q9NQ88 1 +Protein-tyrosine phosphatase, active site [IPR016130] 0.3547961659351911 0.0112560739460162 0.9910191420282064 1.0 1.0 5 Q8NCE2,Q8WUK0 2 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3648f47bc0e468fef234ed598d981fbd19037d23 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "JAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MDH1", "MDH2", "MTMR14", "NCEH1", "NEK9", "NME1", "NME2", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRKCA", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "RIPK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UMPS", "VRK1", "VRK2"], "leading_proteins": ["ACP6", "CTSA", "GSR", "MTMR14", "PTPMT1", "TIGAR", "TXNRD1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4fbc9281cf8ec49c13d1171dfcdfaba3965e2f54 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7e9bbd53b6e967cf55fbb34347026e94c639ef592aeed5a2a9342b72f9ca67ed +size 139006 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..fcde865f190f48d17c8d16a61c9c816bd354b29f --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f4c9976d7d64579890f4cc24a194252f307a81090750fafdf6073887aac06eff +size 74667 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..227d1971e86ec1344badb364f2a83224f3809ae6 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 4.483870967741935 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5e3ef4b615189def58a1357ae3e25f37dea39e04 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..73e06f5df3aaee338252359449d8dd503c66d157 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +EF-Hand 1, calcium-binding site [IPR018247] 0.4111704811005147 1.5511227082992085 0.1208722801883184 0.9815663560455926 0.220414157990463 36 Q9NWM8,Q6NUK1,Q9BPX6,Q9Y680,O75340,O95202,Q14257,Q9BRK5,Q02818,P80303 10 +Beta tubulin, autoregulation binding site [IPR013838] 0.5912913348262101 0.7138479744784358 0.4753211905986509 0.9999999979265228 0.526248461019935 4 Q9BUF5,Q13885 2 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1dc3dfcc43471830555bfc547a7fb531ba0573d5 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "JAK1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PAK1", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKACA", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["FKBP14", "FKBP7", "LETM1", "MICU1", "NUCB1", "NUCB2", "PDCD6", "RCN2", "SDF4", "SLC25A24", "TUBB2A", "TUBB6"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..692f626768fda9070bb0478d95ffc03c15ca8458 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "ABC transporter-like, conserved site [IPR017871]", "1": "AMP-binding, conserved site [IPR020845]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a8dbaaa9c063dee6c4163a854bf05baf809f930f --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:88dbfa77f4d43e2a25b45edc9c7451fe489bba4d08f2ed94226e66e19bbb44e1 +size 141518 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..81eb51d9e03234d9085291a8ebce44d93203dd48 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9192f25ce80dcdef6fe6d278e1c2a64fee6dc7144d9e0a4435c016d8a3e1ebfc +size 141508 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..c48b561d7f8b3abbbb15910f91ba3c075ed58e4e --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2ce9984020147cbb7ddec548a8ed50e9f9732221a622addea2f62115bff27040 +size 109902 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b7ee15d2097b07da70ec6e3394acdcddd53d4819 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 279, + "title": "Average number of proteins per term", + "value": 2.6594982078853047 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..f7db06cf5ddd5e2942fd39db71dc37aa0ce925b0 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cfa5d2c366f45579fbb2290eecd102029642cbbf --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,33 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Haem oxygenase conserved site [IPR018207] 0.9868585732165204 2.3299541624760285 0.0198085738970283 0.9962352085987592 0.071773923600921 2 P09601 1 +3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.901752190237797 1.9593842378504256 0.0500678051833225 0.999999402638367 0.1429190599102789 2 P40939 1 +Thioredoxin, conserved site [IPR017937] 0.6260618867594204 1.7679437746794076 0.0770703036957913 0.9999999998085546 0.1886194274660157 11 O43396,Q96JJ7,Q9H1E5 3 +Tetraspanin, conserved site [IPR018503] 0.9339593114240904 1.7451920629805462 0.080951442366105 0.9999999999409216 0.1930380548730197 3 O60637,O43657 2 +Sterol reductase, conserved site [IPR018083] 0.8488735919900019 1.7242107342093052 0.0846698070266769 0.9999999999809364 0.1990086123293718 2 Q14739 1 +Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.8272841051314183 1.627373686404271 0.1036577566253602 0.999999999999945 0.224190031771128 2 P11279 1 +Syntaxin/epimorphin, conserved site [IPR006012] 0.7716880676479556 1.621733464735276 0.1048604301645079 0.9999999999999624 0.2250466155069055 5 O15400,O60499,Q9P2W9,Q13190 4 +Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.7643205452868777 1.446321914065528 0.1480869320548645 1.0 0.2829261053358688 4 Q8N4Q0,Q8WWV3 2 +Sugar transporter, conserved site [IPR005829] 0.7559449311639767 1.3058110486959826 0.1916168218134646 1.0 0.3383613499111179 2 Q7L0J3 1 +ABC transporter-like, conserved site [IPR017871] 0.5190226360725917 1.229818046417264 0.2187652487864313 1.0 0.3744509473092904 12 P28288,P08183,Q03519,O75027,O14678,P33527 6 +DnaJ domain, conserved site [IPR018253] 0.5305285877721868 1.2250049446911495 0.2205733574693118 1.0 0.3747407028634824 11 Q9NVH1,Q96KC8 2 +Short-chain dehydrogenase/reductase, conserved site [IPR020904] 0.5281433782000715 1.2111760352327694 0.2258279453144107 1.0 0.3772814176210814 11 Q06136,Q8NBN7,Q53GQ0 3 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.7321652065081508 1.1988166838089325 0.230599233784277 1.0 0.3829594418203172 2 Q9BTY2 1 +C-type lectin, conserved site [IPR018378] 0.7090112640801253 1.0952175225383345 0.2734213508036138 1.0 0.4435148655477224 2 Q9UBG0 1 +Proteasome beta-type subunit, conserved site [IPR016050] 0.5311443079509837 1.062745223901321 0.2878975061132243 1.0 0.4490731458314274 8 P28074,P49721 2 +Tubulin, conserved site [IPR017975] 0.5912913348262101 0.7138479744784358 0.4753211905986509 1.0 0.5821960870007429 4 Q9BUF5,Q13885 2 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.6625733632668338 0.6660592046251714 0.5053732587421185 1.0 0.6051465201246826 3 P26583 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.59918648310387 0.625644255328001 0.531548304340425 1.0 0.6257467380210067 2 O00429 1 +AMP-binding, conserved site [IPR020845] 0.4978070175438696 0.5520686256121131 0.5809013365389009 1.0 0.6724957381508437 6 O14975,O95573,O60488,Q6P1M0,P33121 5 +Intermediate filament protein, conserved site [IPR018039] 0.4648605395951138 0.5469858010500646 0.5843884870842948 1.0 0.6737371400682572 7 P07196,P08670 2 +Acyl-CoA-binding protein, ACBP, conserved site [IPR022408] 0.6229708820781936 0.5233947173665091 0.6006995995873972 1.0 0.6868655257577205 3 Q5T8D3 1 +IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.5588235294117533 0.4712776377774592 0.6374424826836103 1.0 0.7200261241648876 2 P12268 1 +Guanylate kinase, conserved site [IPR020590] 0.4807391168180486 0.3695551036986929 0.7117140084117546 1.0 0.7770364198136213 5 Q9NZW5,Q14168,O14936,Q00013 4 +Clathrin adaptor complex, small chain [IPR000804] 0.5758998435054848 0.3682126431552551 0.712714683722725 1.0 0.7770364198136213 3 P61923,P53680 2 +Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.5015644555694492 0.2824155867625559 0.7776248647281567 1.0 0.8409199118571928 2 P82675 1 +RNA polymerase, beta subunit, conserved site [IPR007121] 0.4921777221526768 0.2556563032917631 0.7982162389353125 1.0 0.8474891612378473 2 P30876 1 +GTP1/OBG, conserved site [IPR006074] 0.4918648310387845 0.2547869795560651 0.7988876322779708 1.0 0.8474891612378473 2 P55039 1 +Actin/actin-like conserved site [IPR020902] 0.5176838810641715 0.2062887466060313 0.8365653684016694 1.0 0.87745014204536 3 P61158,P61160 2 +Ubiquitin interacting motif [IPR003903] 0.4367278834244215 0.1727176562948627 0.8628733646537461 1.0 0.9016541900314424 4 Q8IZ07 1 +Ribosomal protein S2, conserved site [IPR018130] 0.457446808510623 0.16852223691835 0.866172451304627 1.0 0.90172430564922 2 Q9Y399 1 +Oxysterol-binding protein, conserved site [IPR018494] 0.4167111466384482 0.1572486605300229 0.8750488797352547 1.0 0.9075785778666768 5 Q9BZF1,Q9H1P3 2 +Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.4187793427230116 0.0297711324003509 0.9762495815650516 1.0 0.99558078947796 3 Q9BXS5,Q96CW1 2 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cadee0edce73594a83eee81674a899a61a028719 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Connexin, conserved site [IPR017990]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Di-trans-poly-cis-decaprenylcistransferase-like, conserved site [IPR018520]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GJA1", "GLA", "GLB1", "GLO1", "GMPPA", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "ING5", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRC2", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NUBP1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP7", "RBFA", "RCL1", "RDH13", "RDX", "RIDA", "RNF2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAP", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC2A4", "SLC4A2", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STRN4", "STX10", "STX12", "STX18", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAF5", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM13", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN10", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP34", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ACBD5", "ACSL1", "ACSL3", "ACSL4", "ACTR2", "ACTR3", "ANKRD13A", "AP1M1", "AP2M1", "AP2S1", "CASK", "COPZ1", "DNAJC1", "DNAJC11", "DNM1L", "DRG2", "FUCA2", "HADHA", "HMGB2", "HMOX1", "HSD17B12", "IMPDH2", "KDSR", "LAMP1", "LBR", "MPP1", "MPP2", "MPP6", "MRC2", "MRPS2", "MRPS5", "NEFL", "OSBPL2", "OSBPL8", "POLR2B", "PSMB2", "PSMB5", 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https://git-lfs.github.com/spec/v1 +oid sha256:6b125dfc981da2248b5d4999cdac0462c1332040bb814501918219fb81e0b2ac +size 452065 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..22b6bc3310fc8a9c8fc4b6d94e7170c183cd233b --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Phospholipid/glycerol acyltransferase [IPR002123] 4 8 2.2334806828393288 0.0255172627986659 2.4611650485436893 6.109223300970874 0.4541526786138767 0.3733328307275969 1.647577392422315 1.6678607828333205 1.200305691546449 0.3080828121567173 0.0002457872884603 0.0742352733278267 0.1419203898220533 0.0557098434243155 0.0007186517412764 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 5 7 2.182020177268643 0.0291080436149202 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0498968875883284 1.0 0.1898352204968973 0.097689242801984 0.0196049214971061 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9c79f72e11ec068349a4808007384ca635fa2e41 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 2586, + "title": "Average number of proteins per term", + "value": 2.1759474091260635 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..807fdf59c4bfcaaf34c418bf45c16429f76fafdd --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ddcda43f86f02b8691b5c008edcea464231add30 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,194 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Phospholipid/glycerol acyltransferase [IPR002123] 0.7580947304029029 2.2334806828393288 0.0255172627986659 1.0 0.0877202998201998 8 Q8NF37,Q9HCL2,Q92604,O15228 4 +Prenylcysteine lyase [IPR010795] 0.9593241551939964 2.2112595225743736 0.0270178706304995 1.0 0.0921744240771395 2 Q9UHG3 1 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.800569000047712 2.182020177268643 0.0291080436149202 1.0 0.0971269687589468 7 Q9HD20,P05023,P20020,P98194,P16615 5 +Reticulon [IPR003388] 0.9376956793988656 2.1672269720317487 0.0302175517246383 1.0 0.0992917265056096 4 O95197,Q9NQC3,O75298 3 +Peptidase S54, rhomboid domain [IPR022764] 0.94180225281602 2.135114550753683 0.0327516543648007 1.0 0.1036034811493765 2 Q6NTF9 1 +Fatty acid hydroxylase [IPR006694] 0.9386733416771036 2.121468578159008 0.033882389486278 1.0 0.105944211344339 2 Q15800 1 +GPAT/DHAPAT, acyltransferase domain [IPR041728] 0.9133291614518264 2.0104121810708206 0.044387582318355 1.0 0.1246322343922542 2 Q9HCL2 1 +Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520] 0.9133291614518264 2.0104121810708206 0.044387582318355 1.0 0.1246322343922542 2 Q9HCL2 1 +BRICHOS domain [IPR007084] 0.9089486858573214 1.9911256068462777 0.046467079914819 1.0 0.1292084609244322 2 Q9Y287 1 +3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.901752190237797 1.9593842378504256 0.0500678051833225 1.0 0.1351517162881755 2 P40939 1 +3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.901752190237797 1.9593842378504256 0.0500678051833225 1.0 0.1351517162881755 2 P40939 1 +ABC transporter type 1, transmembrane domain [IPR011527] 0.7018808777429528 1.9554830167285453 0.0505260859993395 1.0 0.1361046441607207 8 P28288,P08183,Q9NUT2,O75027,Q03519,O14678,P33527 7 +Phospholipase D/Transphosphatidylase [IPR001736] 0.8992490613266584 1.9483276519550976 0.0513757704932613 1.0 0.1372497339830308 2 Q8IV08 1 +Acyl-CoA oxidase, C-terminal [IPR002655] 0.896120150187734 1.9344954298747168 0.0530522434241371 1.0 0.140135956583063 2 Q15067 1 +GOLD domain [IPR009038] 0.7448095952777316 1.9215571063572685 0.05466151023362 1.0 0.1426384111646231 7 P49755,Q9Y3A6,Q9BVK6,Q15363,Q9Y3B3 5 +Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252] 0.885481852315404 1.8873726642973936 0.0591102191602428 1.0 0.1504586433871466 2 Q8NF37 1 +LEM domain [IPR003887] 0.7858708058256585 1.8775281939581077 0.0604457368779356 1.0 0.1525001712842356 6 P42167,Q86XL3,P50402 3 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8767209011264081 1.848461443524963 0.0645356171505389 1.0 0.1586398345544616 2 Q9NVI7 1 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.819605386783588 1.8298603345236153 0.0672708260396428 1.0 0.1638077784538937 5 P20020,P98194,P05023,P16615 4 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.819605386783588 1.8298603345236153 0.0672708260396428 1.0 0.1638077784538937 5 P20020,P98194,P05023,P16615 4 +EF-hand domain [IPR002048] 0.4221498857597118 1.815030121924765 0.0695192805731066 1.0 0.1656504766992601 44 O75071,Q9NWM8,Q6NUK1,Q9BPX6,Q9Y680,Q8NF37,O75340,O95202,Q14257,Q9BRK5,Q02818,P80303 12 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.7600659176924804 1.7612628585559698 0.0781939233052531 1.0 0.1773767418134952 6 Q6P179,P09960,Q9UIQ6,Q9NZ08 4 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.7600659176924804 1.7612628585559698 0.0781939233052531 1.0 0.1773767418134952 6 Q6P179,P09960,Q9UIQ6,Q9NZ08 4 +Glycosyl transferase, family 1 [IPR001296] 0.8535669586983846 1.7452079245424044 0.080948682324297 1.0 0.1820289499918541 2 Q9BT22 1 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.7539178160352003 1.733378447020052 0.0830284258344258 1.0 0.1852558319308241 6 O43169,O15173 2 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.9258215962441232 1.7126763601971808 0.0867720965139895 1.0 0.1883967662076455 3 Q15629,Q96G23 2 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.9255086071987394 1.7114245628693652 0.087002766035148 1.0 0.1883967662076455 3 Q9Y282,Q96RQ1 2 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.9255086071987394 1.7114245628693652 0.087002766035148 1.0 0.1883967662076455 3 Q9Y282,Q96RQ1 2 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.8388610763454503 1.6793490122873056 0.0930840441287066 1.0 0.1981196198492472 2 Q13505 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.8388610763454503 1.6793490122873056 0.0930840441287066 1.0 0.1981196198492472 2 Q13505 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.8074883308050977 1.6294326647568875 0.1032214585445117 1.0 0.2125244361433975 4 Q10472 1 +Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.8188360450563188 1.5893846408938066 0.111973580028938 1.0 0.2239471600578761 2 P20020 1 +ERAP1-like C-terminal domain [IPR024571] 0.7968065122103908 1.5842943484940768 0.1131267512954514 1.0 0.2246895382872791 4 Q6P179,Q9UIQ6,Q9NZ08 3 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.8141426783479333 1.5682603602745997 0.1168203828476823 1.0 0.2292926561722956 2 P98179 1 +Dynamin, N-terminal [IPR045063] 0.6713871143611447 1.5676978314501937 0.1169516680167277 1.0 0.2292926561722956 7 Q8IWA4 1 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.6713871143611447 1.5676978314501937 0.1169516680167277 1.0 0.2292926561722956 7 Q8IWA4 1 +SUN coiled coil domain 2 [IPR040994] 0.8125782227784897 1.561216180959641 0.1184727524179656 1.0 0.2320988922370144 2 O94901 1 +Amino acid transporter, transmembrane domain [IPR013057] 0.8078848560701049 1.5400760968961131 0.1235418055059227 1.0 0.240029383199336 2 Q96QD8 1 +CBS domain [IPR000644] 0.6534185054363503 1.47941689346872 0.1390289278188907 1.0 0.2575421256014695 7 Q8NE01,P51798,P51790 3 +Thioredoxin domain [IPR013766] 0.4513419550662744 1.4633931743418933 0.1433598253130403 1.0 0.2627416784263093 26 Q96JJ7,Q9Y320,O43396,Q9H3N1,Q96J42,Q9H1E5 6 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.7891113892365429 1.4554287513225834 0.1455506016124355 1.0 0.2655502447373973 2 O60506 1 +Ricin B, lectin domain [IPR000772] 0.6916032351714702 1.4471746848752436 0.1478480047878421 1.0 0.267367091175776 6 Q9UBG0,Q10472 2 +Alcohol dehydrogenase, N-terminal [IPR013154] 0.7244484295646729 1.4135383330452036 0.1574974986051158 1.0 0.2799233892734224 5 Q8N4Q0,Q8WWV3 2 +Major facilitator superfamily domain [IPR020846] 0.7564182842830145 1.4126281578840028 0.1577650853030574 1.0 0.280014077277767 4 Q14728,Q9H2V7,Q7L0J3 3 +Sterol-sensing domain [IPR000731] 0.8494522691705709 1.4052132365764831 0.1599578792407836 1.0 0.2830619861682568 3 O15118,P04035 2 +Glycosyltransferase 2-like [IPR001173] 0.6825162127283004 1.4049672829075317 0.1600310073271513 1.0 0.2830619861682568 6 Q10472 1 +Tim44-like domain [IPR007379] 0.7778473091364295 1.4046039223639872 0.1601390896226449 1.0 0.2830619861682568 2 O43615 1 +Syntaxin, N-terminal domain [IPR006011] 0.7709637046307851 1.3735439964372629 0.1695832935155026 1.0 0.2930786969437617 2 O15400 1 +CARG-binding factor, N-terminal [IPR012956] 0.760012515644555 1.3241480445956593 0.1854538819651152 1.0 0.3122289965897057 2 Q99729 1 +G-protein gamma-like domain [IPR015898] 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.3223960964349934 2 P63218 1 +Tim10-like [IPR004217] 0.7257357545397575 1.2814841714766183 0.2000236561145705 1.0 0.326347744297968 4 Q9Y5J6,P62072,Q9Y5J9 3 +BSD domain [IPR005607] 0.7493742177722111 1.2762067725213837 0.2018824352034309 1.0 0.3289596764101722 2 P32780 1 +ABC transporter-like, ATP-binding domain [IPR003439] 0.5190226360725917 1.229818046417264 0.2187652487864313 1.0 0.3432738302016317 12 P28288,P08183,Q03519,O75027,O14678,P33527 6 +CNNM, transmembrane domain [IPR002550] 0.7384230287859779 1.2269292687917053 0.2198491766439203 1.0 0.3432738302016317 2 Q8NE01 1 +Ion transporter-like, CBS domain [IPR044751] 0.7384230287859779 1.2269292687917053 0.2198491766439203 1.0 0.3432738302016317 2 Q8NE01 1 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.7321652065081508 1.1988166838089325 0.230599233784277 1.0 0.3562270711164214 2 Q9BTY2 1 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.7268460575719745 1.1749534289237225 0.2400133482199091 1.0 0.3667729867079838 2 O15460 1 +Autophagy-related, C-terminal [IPR015412] 0.7224655819774666 1.1553269012118077 0.2479565837480406 1.0 0.3754190430751949 2 Q96RL7 1 +JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.5880447742074583 1.1542497154002889 0.2483978056086395 1.0 0.375867013050873 7 Q7L5N1,Q92905,O00303,O00487 4 +Stromal interaction molecule, Orai1-activating region [IPR032393] 0.7183979974968657 1.1371252580351587 0.2554859264017501 1.0 0.3825631764186021 2 Q13586 1 +Band 7 domain [IPR001107] 0.5409384224768495 1.1152840968398925 0.264728698123819 1.0 0.3923142769903702 8 O75477,Q99623,P27105,Q14254 4 +Band 3 cytoplasmic domain [IPR013769] 0.7124530663329407 1.1105670460706571 0.2667547539737471 1.0 0.3937373252146747 2 Q9Y6M7 1 +Bicarbonate transporter, C-terminal [IPR011531] 0.7124530663329407 1.1105670460706571 0.2667547539737471 1.0 0.3937373252146747 2 Q9Y6M7 1 +CD209-like, C-type lectin-like domain [IPR033989] 0.7090112640801253 1.0952175225383345 0.2734213508036138 1.0 0.4001514505818593 2 Q9UBG0 1 +C-type lectin-like [IPR001304] 0.7090112640801253 1.0952175225383345 0.2734213508036138 1.0 0.4001514505818593 2 Q9UBG0 1 +RBM1CTR [IPR012604] 0.7080725907384173 1.0910348652676698 0.2752575414170963 1.0 0.4023832685724201 2 Q96E39 1 +v-SNARE, coiled-coil homology domain [IPR042855] 0.7695791366899696 1.0827732487132773 0.278909082254402 1.0 0.4044890938116434 3 O15498 1 +Longin domain [IPR010908] 0.7695791366899696 1.0827732487132773 0.278909082254402 1.0 0.4044890938116434 3 O15498 1 +LRRC8, pannexin-like TM region [IPR021040] 0.706195244055063 1.082674333709742 0.2789530002507039 1.0 0.4044890938116434 2 Q8TDW0 1 +Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333] 0.7033792240300474 1.0701459171778245 0.2845536336180201 1.0 0.4094912056406232 2 Q9UHQ9 1 +Rpn11/EIF3F, C-terminal [IPR024969] 0.6746005089261919 1.06281157231651 0.2878674104958039 1.0 0.4127786510320649 4 O00487,Q7L5N1 2 +Zinc finger, CHHC-type [IPR012996] 0.7524256651017073 1.0141546887275652 0.3105089457711967 1.0 0.4345108948941096 3 P31943,P52597 2 +PB1 domain [IPR000270] 0.6880475594493052 1.0022293469535504 0.3162328370583664 1.0 0.4401389217615369 2 Q92734 1 +Exosome complex component, N-terminal domain [IPR025721] 0.6836670838548118 0.9829278750450118 0.3256429374848568 1.0 0.4496063194531979 2 Q13868 1 +PSI domain [IPR016201] 0.6808510638297804 0.9705470079782528 0.3317739054353723 1.0 0.4536406378521357 2 P05556 1 +Far upstream element-binding protein, C-terminal [IPR015096] 0.6792866082603339 0.9636783652630164 0.3352072042951062 1.0 0.456956157252053 2 Q92945 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.7362854722691725 0.9500173952007788 0.3421034138734025 1.0 0.4624565751576679 3 Q32P28 1 +Acyltransferase, C-terminal domain [IPR032098] 0.7248826291079751 0.9050203603923296 0.3654546008747676 1.0 0.4789992893371257 3 Q6UWP7,Q92604 2 +Domain of unknown function DUF3517 [IPR021905] 0.7223615125896055 0.8951122667448913 0.3707270772337538 1.0 0.4839476131885348 3 Q70CQ2 1 +Oxidoreductase FAD/NAD(P)-binding [IPR001433] 0.7154828048363391 0.8681605642288709 0.3853064395701913 1.0 0.4933971431391484 3 P16435 1 +Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709] 0.7154828048363391 0.8681605642288709 0.3853064395701913 1.0 0.4933971431391484 3 P16435 1 +FAD-binding domain, ferredoxin reductase-type [IPR017927] 0.7154828048363391 0.8681605642288709 0.3853064395701913 1.0 0.4933971431391484 3 P16435 1 +Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.6555068836045145 0.8602443191555226 0.3896543790180433 1.0 0.4960748780377845 2 O15027 1 +CS domain [IPR007052] 0.4840963547807055 0.8543608636645027 0.3929050734871699 1.0 0.4960748780377845 9 Q9P035,Q15185,Q9HB71 3 +EF hand associated, type-2 [IPR013567] 0.6536295369211436 0.8521660305139337 0.3941219475998094 1.0 0.4960748780377845 2 Q8IXI2 1 +EF hand associated, type-1 [IPR013566] 0.6536295369211436 0.8521660305139337 0.3941219475998094 1.0 0.4960748780377845 2 Q8IXI2 1 +MIRO domain [IPR020860] 0.6536295369211436 0.8521660305139337 0.3941219475998094 1.0 0.4960748780377845 2 Q8IXI2 1 +FAD/NAD(P)-binding domain [IPR023753] 0.5610431523965902 0.837540940194859 0.4022885744988005 1.0 0.5035422331335422 6 Q9Y6N5 1 +Target SNARE coiled-coil homology domain [IPR000727] 0.5128568621878694 0.7791392320469029 0.4358977019074883 1.0 0.5267436715573667 7 O15400,O60499,Q9UNK0,Q13190 4 +NOPS [IPR012975] 0.6888888888888768 0.7652761001358066 0.444107152572144 1.0 0.5343710182780504 3 Q8WXF1,P23246 2 +EB1, C-terminal [IPR004953] 0.6260951188986289 0.7355212671567575 0.462022092717901 1.0 0.5490758877612556 2 Q15555 1 +Fibronectin type II domain [IPR000562] 0.6786476905821646 0.7263160077653008 0.467645068201648 1.0 0.5549931832810746 3 Q9UBV2 1 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.5912913348262101 0.7138479744784358 0.4753211905986509 1.0 0.5615469450036464 4 Q9BUF5,Q13885 2 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.5912913348262101 0.7138479744784358 0.4753211905986509 1.0 0.5615469450036464 4 Q9BUF5,Q13885 2 +AMP-dependent synthetase/ligase [IPR000873] 0.4979630209965758 0.7060326328835148 0.4801678439725332 1.0 0.5654435539676552 7 O14975,O95573,O60488,Q6P1M0,Q9P265,P33121 6 +Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.6113892365456726 0.6748901764068153 0.4997455422330339 1.0 0.5874281691884663 2 Q9NRG0 1 +Peptidase M28 [IPR007484] 0.660571149387086 0.6586377233248139 0.510128432743977 1.0 0.5988552518585398 3 Q969V3 1 +Choline/carnitine acyltransferase domain [IPR039551] 0.6602016299634423 0.6572702094163263 0.5110071881519049 1.0 0.5995755846464729 3 P23786 1 +NIPSNAP [IPR012577] 0.6556681470432768 0.6405487566424775 0.5218159018908619 1.0 0.6111485155297867 3 O75323 1 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.6550860719874629 0.6384094459081496 0.523207183668684 1.0 0.6122234284919533 3 Q9ULX6,O43823 2 +GTPase effector domain [IPR020850] 0.59918648310387 0.625644255328001 0.531548304340425 1.0 0.6196276303955365 2 O00429 1 +Dynamin GTPase effector [IPR003130] 0.59918648310387 0.625644255328001 0.531548304340425 1.0 0.6196276303955365 2 O00429 1 +Dynamin stalk domain [IPR000375] 0.59918648310387 0.625644255328001 0.531548304340425 1.0 0.6196276303955365 2 O00429 1 +Guanylate kinase-like domain [IPR008144] 0.4810404261986908 0.6240184302086846 0.5326154814313342 1.0 0.6196276303955365 7 O14936,Q00013,Q14168,Q9UDY2,Q07157,Q9NZW5 6 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.4810404261986908 0.6240184302086846 0.5326154814313342 1.0 0.6196276303955365 7 O14936,Q00013,Q14168,Q9UDY2,Q07157,Q9NZW5 6 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.4486269760281844 0.6239662683372104 0.5326497379618242 1.0 0.6196276303955365 8 P23458,Q9H5K3 2 +AMP-binding enzyme, C-terminal domain [IPR025110] 0.5664482642123386 0.614144231172041 0.5391200220656063 1.0 0.6260280094574125 4 O14975 1 +SUN domain [IPR012919] 0.6482587842431484 0.6134516013220029 0.539577775379688 1.0 0.6262783335421334 3 O94901 1 +Intermediate filament head, DNA-binding domain [IPR006821] 0.5625860734669725 0.5989254021587882 0.5492226311664572 1.0 0.6360455549469137 4 P07196,P08670 2 +Class II aldolase/adducin N-terminal [IPR001303] 0.5913642052565611 0.5946448872837522 0.5520808687392531 1.0 0.6388896463387469 2 P35611 1 +Exportin-2, central domain [IPR013713] 0.6416275430359999 0.5894582956002284 0.5555538804614448 1.0 0.6422272395499761 3 P55060,O95373 2 +DnaJ domain [IPR001623] 0.3602096337089302 0.5763860223695468 0.5643542900518601 1.0 0.6521091126336507 19 Q96KC8,Q9NVH1,Q9Y2G8 3 +Tudor domain [IPR002999] 0.5015135441932621 0.5682788547083494 0.5698456347561649 1.0 0.6572795769310626 6 Q16637,Q14739 2 +Intermediate filament, rod domain [IPR039008] 0.4648605395951138 0.5469858010500646 0.5843884870842948 1.0 0.6725539063640349 7 P07196,P08670 2 +Extended synaptotagmin, C-terminal C2 domain [IPR037752] 0.5782227784730805 0.5436729177738162 0.5866665720474475 1.0 0.6739759019612169 2 A0FGR8 1 +Synaptotagmin, SMP domain [IPR039010] 0.5782227784730805 0.5436729177738162 0.5866665720474475 1.0 0.6739759019612169 2 A0FGR8 1 +Extended synaptotagmin, C2A domain [IPR037733] 0.5782227784730805 0.5436729177738162 0.5866665720474475 1.0 0.6739759019612169 2 A0FGR8 1 +Extended synaptotagmin, C2B domain [IPR037749] 0.5782227784730805 0.5436729177738162 0.5866665720474475 1.0 0.6739759019612169 2 A0FGR8 1 +Acyl-CoA-binding protein, ACBP [IPR000582] 0.6229708820781936 0.5233947173665091 0.6006995995873972 1.0 0.6885678920802345 3 Q5T8D3 1 +CTP synthase, N-terminal [IPR017456] 0.5666458072590649 0.5000324852728192 0.6170522037613626 1.0 0.7020224368354085 2 Q9NRF8 1 +CTP synthase GATase domain [IPR033828] 0.5666458072590649 0.5000324852728192 0.6170522037613626 1.0 0.7020224368354085 2 Q9NRF8 1 +NudC N-terminal domain [IPR025934] 0.5628911138923541 0.486153509900704 0.6268583303506845 1.0 0.7109893167924869 2 Q8IVD9 1 +IMP dehydrogenase/GMP reductase [IPR001093] 0.5588235294117533 0.4712776377774592 0.6374424826836103 1.0 0.721727784684683 2 P12268 1 +Glutathione S-transferase, N-terminal [IPR004045] 0.4157414651363635 0.4565682371117183 0.647981413705836 1.0 0.7310994484482075 8 Q8TB36,Q9H7Z7 2 +Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.5238491316410919 0.4516210720429309 0.6515419869635524 1.0 0.7344758405787909 4 Q4J6C6 1 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.4713160678045222 0.4390124886783632 0.660652487204421 1.0 0.7437733269092873 6 Q32P28 1 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.4713160678045222 0.4390124886783632 0.660652487204421 1.0 0.7437733269092873 6 Q32P28 1 +Immunoglobulin C1-set [IPR003597] 0.5972557933451974 0.4363467198886537 0.6625851895109509 1.0 0.7446524554868835 3 P04439 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.5972557933451974 0.4363467198886537 0.6625851895109509 1.0 0.7446524554868835 3 P04439 1 +MHC class I-like antigen recognition-like [IPR011161] 0.5972557933451974 0.4363467198886537 0.6625851895109509 1.0 0.7446524554868835 3 P04439 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.5972557933451974 0.4363467198886537 0.6625851895109509 1.0 0.7446524554868835 3 P04439 1 +MoaB/Mog domain [IPR001453] 0.5406758448059955 0.4070665306284998 0.6839591245806642 1.0 0.7617219191066312 2 Q9NQX3 1 +Histone deacetylase domain [IPR023801] 0.5397371714643182 0.4038465260483777 0.6863255808002564 1.0 0.7640283908521149 2 Q13547 1 +Nucleotidyl transferase domain [IPR005835] 0.5391113892365333 0.4017056380500927 0.6879006747114595 1.0 0.765062995012468 2 Q9NR50 1 +BRO1 domain [IPR004328] 0.5369211514392908 0.3942492511833922 0.6933970269186907 1.0 0.7685952825656962 2 Q8WUM4 1 +MRG domain [IPR026541] 0.5366082603253955 0.3931887473560802 0.6941800801406508 1.0 0.7691301145003098 2 Q9UBU8 1 +Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187] 0.5356695869837175 0.3900143288570299 0.6965259514073896 1.0 0.771068540385064 2 Q8WUM0 1 +Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468] 0.5784037558685422 0.3759855114957027 0.7069276672512044 1.0 0.7799125202694601 3 A0FGR8,Q8IWB9 2 +Heat shock chaperonin-binding [IPR006636] 0.4781306590564825 0.359938127275241 0.7188934038152435 1.0 0.7894975615969964 5 Q9UMX0 1 +Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034] 0.5234668335419144 0.3497423187129543 0.7265320911985129 1.0 0.7947597241283225 2 Q2NL82 1 +AARP2CN [IPR012948] 0.5234668335419144 0.3497423187129543 0.7265320911985129 1.0 0.7947597241283225 2 Q2NL82 1 +Bms1/Tsr1-type G domain [IPR030387] 0.5234668335419144 0.3497423187129543 0.7265320911985129 1.0 0.7947597241283225 2 Q2NL82 1 +Potentiating neddylation domain [IPR005176] 0.5604880813469122 0.3217296230459757 0.7476575341235452 1.0 0.8133960383859856 3 Q96GG9 1 +Stromalin conservative domain [IPR020839] 0.5125156445556813 0.3152502868084432 0.7525716272368392 1.0 0.8173667484395071 2 Q8WVM7 1 +STAG [IPR013721] 0.5125156445556813 0.3152502868084432 0.7525716272368392 1.0 0.8173667484395071 2 Q8WVM7 1 +Major sperm protein (MSP) domain [IPR000535] 0.5580594679186307 0.3146264965964742 0.753045258764006 1.0 0.8174091953512662 3 Q8NHP6,Q9P0L0 2 +L27 domain, C-terminal [IPR014775] 0.480588603631811 0.3021390354044653 0.7625460761823899 1.0 0.8235622163470335 4 Q9NZW5,Q14168,O14936 3 +L27 domain [IPR004172] 0.480588603631811 0.3021390354044653 0.7625460761823899 1.0 0.8235622163470335 4 Q9NZW5,Q14168,O14936 3 +Zinc finger, UBP-type [IPR001607] 0.5081351689611879 0.3019125132776486 0.7627187564104716 1.0 0.8235622163470335 2 P45974 1 +ZU5 domain [IPR000906] 0.504693366708376 0.2916226280570583 0.770575172419774 1.0 0.8296249738915048 2 Q12955 1 +Ribosomal protein S5, N-terminal [IPR013810] 0.5015644555694492 0.2824155867625559 0.7776248647281567 1.0 0.8344140664676404 2 P82675 1 +Ribosomal protein S5, C-terminal [IPR005324] 0.5015644555694492 0.2824155867625559 0.7776248647281567 1.0 0.8344140664676404 2 P82675 1 +SCP2 sterol-binding domain [IPR003033] 0.544913928012527 0.2772857684576214 0.7815606864200255 1.0 0.8375946684965545 3 P51659,Q6YN16 2 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.3678680301240127 0.2749865093003601 0.7833266029318888 1.0 0.8384447827739505 10 Q9Y680 1 +Exportin-1/Importin-beta-like [IPR013598] 0.4708829054477206 0.2713638725208795 0.7861111854312945 1.0 0.8407293323098957 4 O14980,Q9Y5L0,Q9HAV4 3 +RNA polymerase Rpb2, domain 7 [IPR007641] 0.4921777221526768 0.2556563032917631 0.7982162389353125 1.0 0.8512112139739043 2 P30876 1 +DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120] 0.4921777221526768 0.2556563032917631 0.7982162389353125 1.0 0.8512112139739043 2 P30876 1 +RNA polymerase Rpb2, domain 2 [IPR007642] 0.4921777221526768 0.2556563032917631 0.7982162389353125 1.0 0.8512112139739043 2 P30876 1 +RNA polymerase Rpb2, domain 3 [IPR007645] 0.4921777221526768 0.2556563032917631 0.7982162389353125 1.0 0.8512112139739043 2 P30876 1 +RNA polymerase, beta subunit, protrusion [IPR007644] 0.4921777221526768 0.2556563032917631 0.7982162389353125 1.0 0.8512112139739043 2 P30876 1 +GTP binding protein, second domain [IPR031662] 0.4918648310387845 0.2547869795560651 0.7988876322779708 1.0 0.8515760169294445 2 P55039 1 +SGS domain [IPR007699] 0.4899874843554301 0.2496021805543604 0.8028950121168446 1.0 0.8549020536027065 2 Q9HB71 1 +Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.3625722732293469 0.249466892533119 0.8029996474095027 1.0 0.8549020536027065 10 Q15067,O15254 2 +Ribosomal protein S7 domain [IPR023798] 0.4884230287859701 0.2453224814647796 0.8062067458186468 1.0 0.8579632282662637 2 Q9Y2R9 1 +PDZ domain 6 [IPR041489] 0.4871714643304021 0.2419256842182067 0.8088377480486146 1.0 0.8593485687977476 2 Q92614 1 +Vps4 oligomerisation, C-terminal [IPR015415] 0.4868585732165065 0.2410802430114363 0.8094929250353378 1.0 0.8596914596063177 2 P55072 1 +Septin-type guanine nucleotide-binding (G) domain [IPR030379] 0.4434738513028119 0.2394648173235025 0.8107451746259391 1.0 0.8599355029119768 5 Q16181 1 +AP complex, mu/sigma subunit [IPR022775] 0.4191729323308379 0.2361000057368944 0.8133550694783744 1.0 0.8613170391773449 6 P48444,Q96CW1,Q92572,P61923,P53680 5 +Glutamine amidotransferase [IPR017926] 0.4517845961177277 0.2142557248656212 0.8303476427152261 1.0 0.8767761269500344 4 Q9NRF8,P49915,P17812 3 +Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099] 0.5164319248826356 0.2032423363083622 0.838945623721755 1.0 0.8826335976177617 3 Q16881,P00390 2 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.4621401752190087 0.1791649271005668 0.8578082022034197 1.0 0.8999156230823705 2 P51116 1 +Importin-beta, N-terminal domain [IPR001494] 0.3277864992150831 0.1636194286746511 0.8700307489611498 1.0 0.9119981827375492 13 Q92973,Q14974,O14980,Q96P70,Q9UIA9,O00410,O95373,P55060,O15397,Q8TEX9,O43592,Q9HAV4 12 +VHS domain [IPR002014] 0.4477471839799601 0.14767746336222 0.882597318230214 1.0 0.9206924828331317 2 O14964 1 +Glutamine amidotransferase type 2 domain [IPR017932] 0.4851330203442974 0.1336929814368774 0.8936453553407726 1.0 0.9295924734156228 3 Q06203,Q06210 2 +Mu homology domain [IPR028565] 0.4189104571070695 0.1278408269337856 0.8982749399077719 1.0 0.9332820388113692 4 P48444,Q9BXS5,Q96CW1 3 +Kinesin-like [IPR022164] 0.4321026282853445 0.1173410442837907 0.906589801035088 1.0 0.9407870086182736 2 Q12756 1 +Kinesin-like KIF1-type [IPR022140] 0.4321026282853445 0.1173410442837907 0.906589801035088 1.0 0.9407870086182736 2 Q12756 1 +Metastasis-associated protein MTA1, R1 domain [IPR035170] 0.4744913928012615 0.1130261265306512 0.9100098419566448 1.0 0.943578769566914 3 O94776,Q13330 2 +C2 domain [IPR000008] 0.3159945865690592 0.105516949183123 0.9159656215615716 1.0 0.948993228108263 13 Q96PU5 1 +Arfaptin homology (AH) domain [IPR010504] 0.4214643304130052 0.0990192876326041 0.9211229560463 1.0 0.953572443689244 2 P53365 1 +Ubiquitin system component CUE [IPR003892] 0.3962636305420852 0.0778799033378959 0.937923585662189 1.0 0.969344672375831 4 Q9UKV5 1 +F-BAR domain [IPR031160] 0.4466353677621372 0.0662248441105149 0.9471988174487388 1.0 0.9742215169699724 3 Q15642,Q9UKS6 2 +FCH domain [IPR001060] 0.4466353677621372 0.0662248441105149 0.9471988174487388 1.0 0.9742215169699724 3 Q15642,Q9UKS6 2 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.4460093896713716 0.0652938043378905 0.947940075241846 1.0 0.9742215169699724 3 Q9UL46,P61289 2 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.4460093896713716 0.0652938043378905 0.947940075241846 1.0 0.9742215169699724 3 Q9UL46,P61289 2 +Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297] 0.3967459324155041 0.0634555566915666 0.9494037485040838 1.0 0.975042928368372 2 Q9Y237 1 +Chaperone DnaJ, C-terminal [IPR002939] 0.3637218045112881 0.0624179958596962 0.9502299642783132 1.0 0.9755040443127104 6 Q96EY1,Q9UBS4,Q9UDY4,O60884,P31689 5 +AGC-kinase, C-terminal [IPR000961] 0.323400852470909 0.0560486207180876 0.9553030742761386 1.0 0.979934053977824 8 P31751 1 +Protein kinase, C-terminal [IPR017892] 0.3258839939001091 0.0079360932183735 0.993667980214801 1.0 1.0 7 P31751 1 +Protein-tyrosine phosphatase, catalytic [IPR003595] 0.3254067584480495 0.0075409656702135 0.9939832369432846 1.0 1.0 2 P18031 1 +Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.3254067584480495 0.0075409656702135 0.9939832369432846 1.0 1.0 2 P18031 1 +Heat shock protein DnaJ, cysteine-rich domain [IPR001305] 0.3893583724569718 0.0016453335135337 0.9986872143844918 1.0 1.0 3 O60884,P31689 2 +YTH domain [IPR007275] 0.3022528160200145 0.0001546855124629 0.9998765788183182 1.0 1.0 2 Q7Z739 1 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a1b1c45ff6fe9dac362d2e2a99efe97c957f0b09 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA C-terminal domain [IPR032423]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-amylase/branching enzyme, C-terminal all beta [IPR006048]", "Alpha-dystroglycan N-terminal domain 2 [IPR041631]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 1 [IPR041880]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 2 [IPR041882]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B(0)AT2, solute-binding domain [IPR042934]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BET1, SNARE domain [IPR039899]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin/lipoyl attachment [IPR000089]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARD domain [IPR001315]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COMM domain [IPR017920]", "COMMD1 N-terminal domain [IPR033776]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COQ9 [IPR013718]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein H, C-terminal [IPR008426]", "Centrosomal protein of 290kDa, coiled-coil region [IPR032321]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain [IPR041715]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical Protein Kinase C alpha, catalytic domain [IPR034663]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Connexin, N-terminal [IPR013092]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEUBAD domain [IPR044867]", "DFDF domain [IPR025762]", "DG-type SEA domain [IPR030398]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mitochondrial polymerase, exonuclease domain [IPR041336]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein Rad51-like, C-terminal [IPR013632]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA recombination and repair protein RecA-like, ATP-binding domain [IPR020588]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor Dna2, N-terminal [IPR014808]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family A, palm domain [IPR001098]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxycytidylate deaminase domain [IPR035105]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dienelactone hydrolase [IPR002925]", "Dihydrofolate reductase domain [IPR001796]", "Dihydroorotate dehydrogenase domain [IPR005720]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF4757 [IPR031865]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-binding protein, first C-terminal SH3 domain [IPR035820]", "Dynamin-binding protein, first N-terminal SH3 domain [IPR035817]", "Dynamin-binding protein, second N-terminal SH3 domain [IPR035818]", "Dynamin-binding protein, third N-terminal SH3 domain [IPR035819]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "Dystroglycan, C-terminal [IPR008465]", "Dystroglycan-type cadherin-like [IPR006644]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 Ubiquitin ligase MUL1-like [IPR022170]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase AMFR, Ube2g2-binding region [IPR040675]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXOG, C-terminal [IPR041003]", "EYA domain [IPR006545]", "EYA domain, metazoan [IPR042577]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM192A/Fyv6, N-terminal [IPR019331]", "FAM3C (ILEI) domain [IPR039475]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FCP1-like phosphatase, C-terminal [IPR015388]", "FCP1-like phosphatase, phosphatase domain [IPR011947]", "FDF domain [IPR019050]", "FERM F1 lobe ubiquitin-like domain [IPR041155]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FLYWCH-type zinc finger-containing protein, N-terminal [IPR029279]", "FMP27, C-terminal [IPR019443]", "FMP27, GFWDK domain [IPR019441]", "FMP27, N-terminal [IPR019439]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferric reductase transmembrane component-like domain [IPR013130]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein [IPR003382]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Folliculin, DENN domain [IPR032035]", "Folliculin/SMCR8, longin domain [IPR037520]", "Folliculin/SMCR8, tripartite DENN domain [IPR037521]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, C-terminal [IPR005793]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G patch domain-containing protein, N-terminal [IPR011666]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galactosyltransferase, C-terminal [IPR027791]", "Galactosyltransferase, N-terminal [IPR027995]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gap junction alpha-1 protein (Cx43), C-terminal [IPR013124]", "Gap junction protein, cysteine-rich domain [IPR019570]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 13, N-terminal [IPR004193]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histidyl-anticodon-binding [IPR033656]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase complex subunit SAP130, C-terminal domain [IPR031963]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "Hypoxia induced protein, domain [IPR007667]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISG20, DEDDh 3'-5' exonuclease domain [IPR037433]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Impact, N-terminal [IPR001498]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Inhibitor of growth protein, N-terminal histone-binding [IPR024610]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JAK, FERM F2 lobe domain [IPR041046]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "Jak1, pleckstrin homology-like domain [IPR041381]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "LysM domain [IPR018392]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MALT1 immunoglobulin-like domain [IPR041077]", "MALT1, death domain [IPR037940]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MTMR14, PH-GRAM domain [IPR039803]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA formyltransferase, N-terminal domain [IPR041711]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "MgsA AAA+ ATPase C-terminal [IPR021886]", "Mib-herc2 [IPR010606]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Morc, S5 domain 2-like [IPR041006]", "Mot1, ATP-binding domain [IPR044078]", "Mot1, central domain [IPR022707]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-CoR, GPS2-interacting domain [IPR031557]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH dehydrogenase subunit 5, C-terminal [IPR010934]", "NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal [IPR001516]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit [IPR001750]", "NADH:ubiquinone oxidoreductase intermediate-associated protein 30 [IPR013857]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFRKB winged helix-like domain [IPR025220]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PB1 domain [IPR000270]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRELI/MSF1 domain [IPR006797]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Patatin-like phospholipase domain [IPR002641]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Phox-associated domain [IPR003114]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein SirB1, N-terminal [IPR032698]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative RNA-binding protein 47, RNA recognition motif 2 [IPR034440]", "Putative RNA-binding protein 47, RNA recognition motif 3 [IPR034445]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM7, RNA recognition motif [IPR034500]", "RBM8, RNA recognition motif [IPR033744]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad18, zinc finger UBZ4-type [IPR006642]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad51/DMC1/RadA [IPR033925]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras-associating (RA) domain [IPR000159]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Retinoblastoma-associated protein, A-box [IPR002720]", "Retinoblastoma-associated protein, B-box [IPR002719]", "Retinoblastoma-associated protein, C-terminal [IPR015030]", "Retinoblastoma-associated protein, N-terminal [IPR024599]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-activating protein, FF domain [IPR032835]", "Rho GTPase-activating protein, pG1 and pG2 domain [IPR045786]", "Rho GTPase-activating protein, pG1 domain [IPR039007]", "Rho GTPase-activating protein, pG2 domain [IPR039006]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF4, RNA recognition motif [IPR034369]", "SCAF8, RNA recognition motif [IPR034370]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD2/Set2, SET domain [IPR044437]", "SETD3, SET domain [IPR044428]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD3, SET domain [IPR044420]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX19, PX domain [IPR037909]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAR protein, homodimerisation region [IPR032377]", "STARD11, START domain [IPR041952]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sde2, N-terminal ubiquitin domain [IPR024974]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set2 Rpb1 interacting domain [IPR013257]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm8 [IPR034103]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, C-terminal [IPR013937]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Sphingolipid delta4-desaturase, N-terminal [IPR013866]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromal interaction molecule 1, SAM domain [IPR037609]", "Stromal interaction molecule 2, SAM domain [IPR037610]", "Stromal interaction molecule, Orai1-activating region [IPR032393]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfatase-modifying factor enzyme [IPR005532]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TEA/ATTS domain [IPR000818]", "TFA2, Winged helix domain 2 [IPR040501]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIID subunit TAF5, NTD2 domain [IPR007582]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TFIIH p62 subunit, N-terminal [IPR013876]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TNF receptor-associated factor 2, MATH domain [IPR037305]", "TNF receptor-associated factor, BIRC3 binding domain [IPR032070]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat protein 7, N-terminal [IPR045819]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription factor TFIIE beta subunit, DNA-binding domain [IPR003166]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBAC2, UBA domain [IPR041928]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glycosyltransferase family, conserved site [IPR035595]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "UVR domain [IPR001943]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 13D, UBA domain [IPR041969]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WRNIP1, ubiquitin-binding domain [IPR040539]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "Xrn1, helical domain [IPR041412]", "YAP binding domain [IPR041086]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "ZZEF1, zinc finger, ZZ-type [IPR041986]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FLYWCH-type [IPR007588]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, TRAF-type [IPR001293]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ACY1", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFAP1", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG5", "ALKBH5", "AMFR", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC10", "ARMCX3", "ARMT1", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B4GALT1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAP18", "BAZ1A", "BAZ1B", "BCAP31", "BCKDHB", "BCS1L", "BEND3", "BET1", "BIRC6", "BLVRA", "BMS1", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRIX1", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf35", "C2CD2", "C2CD5", "CACYBP", "CAD", "CALCOCO1", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CARM1", "CARS", "CASK", "CASP2", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC97", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPV", "CEP170", "CEP290", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLTC", "CLUH", "CMBL", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNPY2", "COA3", "COASY", "COIL", "COL4A3BP", "COLEC12", "COMMD1", "COMMD7", "COMMD8", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CROT", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC27", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "DAG1", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCP1A", "DCTD", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHFR", "DHODH", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC19", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "EARS2", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM129B", "FAM192A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBXO21", "FBXO22", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNBP4", "FNDC3A", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCN1", "GDAP1", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GHITM", "GIGYF2", "GINS3", "GINS4", "GIPC1", "GJA1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH1", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPB11", "HSPBP1", "HSPH1", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INTS1", "INTS11", "INTS14", "INTS3", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISG20L2", "ISOC1", "ISYNA1", "ITGB1", "ITM2B", "ITM2C", "ITPRIP", "IVD", "IWS1", "JAK1", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "MACF1", "MAGED2", "MAK16", "MALT1", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MEPCE", "METTL7B", "MFN1", "MFN2", "MFSD10", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL24", "MRPL39", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTFMT", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTMR14", "MTOR", "MTPAP", "MTR", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCBP1", "NCEH1", "NCKIPSD", "NCL", "NCLN", "NCOR1", "NCSTN", "ND5", "NDC80", "NDUFA10", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NEMF", "NENF", "NF1", "NFATC2IP", "NFRKB", "NFS1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN5", "NTPCR", "NUB1", "NUBP1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OBSL1", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCM1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDXK", "PEF1", "PELO", "PELP1", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PICALM", "PIGG", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POMK", "POP1", "POR", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRELID1", "PRELID3B", "PREP", "PREPL", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PVR", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB29", "RAB2A", "RAB31", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RARS", "RARS2", "RAVER1", "RB1", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM47", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIPK1", "RMND1", "RNASEH2A", "RNF2", "RNF25", "RNF40", "RNMT", "RNPEP", "RNPS1", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRP12", "RRP7A", "RSF1", "RTCA", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SC5D", "SCAF4", "SCAF8", "SCAP", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SDAD1", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SETD2", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC2A4", "SLC38A2", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD3", "SNAP47", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX19", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC25", "SPECC1L", "SPEN", "SPNS1", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STAU1", "STEAP3", "STIM1", "STIM2", "STIP1", "STK4", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STRN4", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF5", "TAF6L", "TAGLN2", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRKH", "TEAD1", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TEX2", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THYN1", "TIA1", "TIAL1", "TIMM10", "TIMM10B", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TKT", "TLN1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM104", "TMEM201", "TMEM205", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOX4", "TP53", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM13", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIO", "TRIP10", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSR1", "TST", "TSTA3", "TTC4", "TTC7B", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUBGCP5", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UGDH", "UGGT1", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VIM", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS13D", "VPS16", "VPS18", "VPS29", "VPS37B", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WASF2", "WDHD1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WRNIP1", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YBX3", "YIPF4", "YKT6", "YME1L1", "YTHDC1", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF131", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZNF830", "ZPR1", "ZRANB2", "ZYX", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ACBD5", "ACOX1", "ACOX3", "ACSL1", "ACSL3", "ACSL4", "ADD1", "AKAP8", "AKAP8L", "AKT2", "ALG1", "AMFR", "ANK3", "ANKLE2", "AP1M1", "AP2M1", "AP2S1", "AP3S1", "ARCN1", "ARFIP2", "ATAD3A", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "CACYBP", "CASK", "CERS2", "CHRAC1", "CLCN3", "CLCN7", "CNNM3", "COPS5", "COPS6", "COPZ1", "CPT2", "CSE1L", "CTPS1", "CTPS2", "CYB5B", "CYB5R1", "DCUN1D1", "DIP2B", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC11", "DNAJC16", "DNM1L", "DRG2", "EFCAB14", "EIF2B3", "EIF3F", "EMD", "ERAP1", "ERAP2", "ERGIC2", "ERGIC3", "ERLIN1", "ESYT2", "EXOSC2", "FKBP14", "FKBP7", "FLOT2", "FUCA2", "FXR2", "GALNT1", "GDAP1", "GFPT1", "GMPS", "GNG5", "GNPAT", "GPAM", "GPHN", "GSR", "GTF2H1", "HACD3", "HADHA", "HDAC1", "HGS", "HLA-A", "HMGCR", "HNRNPAB", "HNRNPF", "HNRNPH1", "HSD17B4", "HSDL2", "IMPDH2", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "ITGB1", "ITM2B", "JAK1", "KHSRP", "KIF1A", "KPNB1", "LBR", "LCLAT1", "LETM1", "LNPEP", "LPCAT1", "LPGAT1", "LRRC8C", "LTA4H", "MAPRE2", "MFN1", "MFSD10", "MICU1", "MORF4L1", "MOSPD2", "MPP1", "MPP2", "MPP6", "MRC2", "MRPS5", "MRPS7", "MSMO1", "MTA1", "MTA2", "MTX1", "MYO18A", "NCLN", "NEDD4L", "NEFL", "NIPSNAP2", "NPC1", "NUCB1", "NUCB2", "NUDCD3", "NUP133", "P3H1", "P4HA2", "PACSIN3", "PCYOX1", "PDCD6", "PDCD6IP", "PGRMC2", "PHB2", "PIN4", "PLD3", "POLR2B", "POMK", "POR", "PPAT", "PREPL", "PSMD14", "PSME2", "PSME3", "PSPC1", "PTGES2", "PTGES3", "PTPN1", "RBM3", "RBMXL1", "RCN2", "RHBDD2", "RHOT1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "SDF4", "SEC16A", "SEL1L", "SEPT7", "SFPQ", "SLC25A24", "SLC27A2", "SLC27A4", "SLC38A2", "SLC4A7", "SMN1*", "SPNS1", "SQOR", "STAG1", "STIM1", "STOM", "STX10", "STX5", "STX7", "STX8", "SUN1", "SV2A", "SYNCRIP", "TAP2", "TEX2", "TFG", "TIMM10", "TIMM10B", "TIMM44", "TIMM8B", "TJP1", "TJP2", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMPO", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TRAM1", "TRIP10", "TSR1", "TUBB2A", "TUBB6", "TXNDC15", "TXNL1", "TXNRD1", "UBQLN1", "USP34", "USP5", "VAPA", "VCP", "VIM", "VPS13A", "XPO1", "XPO5", "XPO7", "XPOT", "YKT6", "YTHDF3", "ZADH2"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..53e469cf5e28b46b95f50be70f54024c8afc5b8d --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "P-type ATPase [IPR001757]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6396e35b5faa42e2cc70928a6e1c98e25db2fba4 --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:95962bc761e474f42aeb0abbf8e6df2efb0ac14fe99dd4954b41972212f4f7cf +size 186691 diff --git a/interpro_family/advanced/plot_1.png b/interpro_family/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..2d8b243cd5f2d58532ad441cf82ccfe25305bae2 --- /dev/null +++ b/interpro_family/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b00c59a3850f9b9cbdc8dfee1788a1eefaf629441b4e0e8080c9ae93ea31d37c +size 182772 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..abbe6b6eacfc8cd1af3e908695f9169308d05af5 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "P-type ATPase [IPR001757]", "2": "Short-chain dehydrogenase/reductase SDR [IPR002347]", "3": "Small GTPase [IPR001806]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2a61cba4dbd62aed6fd574eb44402157d3f16e5e --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f00fa665b464d6badca266fda56d0c99604d62258698f284c4311cd80c149d84 +size 141022 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..991252c29f8383c9cd09c3f84b30b9e9d35a37a1 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:12ad1551f811d046cb8aaf5e1ed0e0168cfe34d192252bb004eb1e5d28ead9de +size 131773 diff --git a/interpro_family/basic/plot_2.png b/interpro_family/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..614911d90e3b26a53969ecee13a9bd9990ebfc7a --- /dev/null +++ b/interpro_family/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0fc9c79de08f1400a03c61381b1f8b2e8c21ec97998ce12d569b900a8a16ba19 +size 146172 diff --git a/interpro_family/basic/plot_3.png b/interpro_family/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..e9b2b23b936e8e7fe2ff2dc56c9e928942848dac --- /dev/null +++ b/interpro_family/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:589045d164ef2a1b6e5243186209cf261cbea25603681cf38da103d63d0f3d82 +size 145430 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..1288b3943126726cb2df99cd693162f538ecc2d7 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:886dd6882847fee2ea8ab74c46f376026e571427728c45d550bcfccd92e7e31d +size 610714 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9275a6b3781e98f0abf1db2b46bf52cf62faf15d --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier protein [IPR002067] 12 13 2.68303348126065 0.0072957685839014 5.686893203883495 11.07766990291262 0.8032246115450145 0.31892620527414 3.2338505495684404 1.5403272908315857 1.3918146051602212 0.3274613788058813 7.400221131341273e-05 1.0 0.1741653971767485 0.0828772873031817 2.0924091743074405e-06 +P-type ATPase [IPR001757] 5 7 2.182020177268643 0.0291080436149202 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0498968875883284 1.0 0.1898352204968973 0.097689242801984 0.0196049214971061 +TB2/DP1/HVA22-related protein [IPR004345] 4 5 2.0223538894796644 0.0431398050642388 1.1925925925925926 2.493827160493827 0.6563009955923319 0.3578956191423959 1.0073529397040124 1.2123180203528214 1.352516575209657 0.3176365809080326 2.974934102554946e-05 1.0 1.0 0.0002629541815867 1.478260276089152e-06 +Transmembrane emp24 domain-containing protein [IPR015720] 4 6 1.990588087222796 0.0465261909991217 2.6432038834951457 5.099514563106796 0.3626508447128717 0.2724944971681708 1.287119696753696 0.8431907483703972 1.4713835809049645 0.2794327521776852 0.0001305701149647 1.0 1.0 0.1775366954381628 1.2721849129246575e-05 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9a24a0b811107a0ca5060de24bd1ff4a6b0ababb --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 2516, + "title": "Average number of proteins per term", + "value": 1.2837837837837838 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..5bc49c0146b9471d4ff679a2927ee3ea05eab2d5 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1416da012a24f2def96ccbb913185e26f7428a6f --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,139 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier protein [IPR002067] 0.7579277864991983 2.68303348126065 0.0072957685839014 0.999999990027578 0.0266804560422908 13 Q9H936,Q9BQT8,O43808,Q8TBP6,Q9UJS0,P12236,P05141,P12235,Q9HC21,Q86VD7,Q6NUK1,O75746 12 +Tetraspanin, animals [IPR000301] 0.996245306633292 2.3701424540074805 0.0177812327916151 1.0 0.0484978327464811 2 O43657 1 +Haem oxygenase-like [IPR016053] 0.9868585732165204 2.3299541624760285 0.0198085738970283 1.0 0.0522267604533937 2 P09601 1 +Haem oxygenase [IPR002051] 0.9868585732165204 2.3299541624760285 0.0198085738970283 1.0 0.0522267604533937 2 P09601 1 +Mitochondrial carrier UCP-like [IPR002030] 0.9796620775969962 2.299047378197932 0.0215022491107088 1.0 0.0554299782403109 2 Q9H2D1 1 +Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708] 0.9727784730913658 2.269407299405169 0.0232435687119401 1.0 0.0584223964827585 2 Q8N8Q8 1 +Nucleobindin [IPR040250] 0.9721526908635804 2.266709033616453 0.0234080062065991 1.0 0.0587695022937157 2 P80303 1 +Prenylcysteine oxidase [IPR017046] 0.9593241551939964 2.2112595225743736 0.0270178706304995 1.0 0.0645555199490378 2 Q9UHG3 1 +P-type ATPase [IPR001757] 0.800569000047712 2.182020177268643 0.0291080436149202 1.0 0.0681897930494779 7 Q9HD20,P05023,P20020,P98194,P16615 5 +Sulfotransferase [IPR005331] 0.95056320400501 2.1732453067347803 0.0297618594850039 1.0 0.0693341096891389 2 Q8NCH0 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.929286608260332 2.080444151183968 0.0374848131805891 1.0 0.0808313766926646 2 Q5VW38 1 +Bax inhibitor 1-related [IPR006214] 0.9270963704630784 2.070853341743847 0.0383725035831632 1.0 0.082096274672822 2 Q9H3K2 1 +CD36 family [IPR002159] 0.9214643304130156 2.0461597103578524 0.0407406598616968 1.0 0.0855415534179955 2 Q14108 1 +Nonaspanin (TM9SF) [IPR004240] 0.9198998748435536 2.0392923783795984 0.0414208558583819 1.0 0.0864853720661319 2 Q9HD45 1 +Bcl2-like [IPR002475] 0.918335419274092 2.0324216030526014 0.0421109929251561 1.0 0.0875630233055313 2 Q9BXK5 1 +Bcl-2 family [IPR026298] 0.918335419274092 2.0324216030526014 0.0421109929251561 1.0 0.0875630233055313 2 Q9BXK5 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9173967459324228 2.028297492049424 0.0425298947880692 1.0 0.0880654069580749 2 Q93050 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9173967459324228 2.028297492049424 0.0425298947880692 1.0 0.0880654069580749 2 Q93050 1 +TB2/DP1/HVA22-related protein [IPR004345] 0.8647040400876804 2.0223538894796644 0.0431398050642388 1.0 0.0888213989702332 5 Q9H6H4,Q00765,Q6NUK4,Q9BRK0 4 +Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284] 0.9133291614518264 2.0104121810708206 0.044387582318355 1.0 0.0910180579567899 2 Q9HCL2 1 +Integral membrane protein 2 [IPR040145] 0.9089486858573214 1.9911256068462777 0.046467079914819 1.0 0.0938292122639307 2 Q9Y287 1 +Transmembrane emp24 domain-containing protein [IPR015720] 0.811244706587767 1.9905880872227957 0.0465261909991217 1.0 0.093873212954122 6 P49755,Q9BVK6,Q9Y3A6,Q9Y3B3 4 +MICOS complex subunit MIC26/MIC27, animal [IPR033182] 0.9076971214017636 1.9856103602072717 0.0470766051944089 1.0 0.0944535396085589 2 Q9BUR5 1 +MICOS complex subunit MIC26/MIC27 [IPR019166] 0.9076971214017636 1.9856103602072717 0.0470766051944089 1.0 0.0944535396085589 2 Q9BUR5 1 +CDP-alcohol phosphatidyltransferase [IPR000462] 0.9064455569461892 1.98009299939216 0.0476930796490044 1.0 0.0953861592980089 2 Q9Y6K0 1 +Cytochrome P450 [IPR001128] 0.905819774718408 1.9773335292612144 0.0480039420705482 1.0 0.0958554906742058 2 Q6UW02 1 +Eukaryotic porin/Tom40 [IPR027246] 0.8891671884783854 1.9697386441382327 0.048868331634758 1.0 0.097042401257341 4 Q9Y277,P45880,P21796 3 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.9026908635794868 1.9635283317365668 0.0495848157646947 1.0 0.0977706868839906 2 O96005 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.9026908635794868 1.9635283317365668 0.0495848157646947 1.0 0.0977706868839906 2 O96005 1 +Oligosaccharyl transferase, STT3 subunit [IPR003674] 0.9020650813517012 1.9607657318120704 0.0499063572536555 1.0 0.0981192682514158 2 P46977 1 +Porin, eukaryotic type [IPR001925] 0.9843505477308296 1.9450560936730248 0.0517682274853088 1.0 0.1007338440472057 3 Q9Y277,P45880 2 +Class I-like SAM-dependent O-methyltransferase [IPR002935] 0.8983103879849905 1.9441793192593773 0.0518738307681765 1.0 0.1008613278305503 2 P21964 1 +Peroxisomal acyl-coenzyme A oxidase [IPR034171] 0.896120150187734 1.9344954298747168 0.0530522434241371 1.0 0.1022388904326803 2 Q15067 1 +Acyl-CoA oxidase [IPR012258] 0.896120150187734 1.9344954298747168 0.0530522434241371 1.0 0.1022388904326803 2 Q15067 1 +Protein-tyrosine phosphatase-like, PTPLA [IPR007482] 0.8945556946182791 1.9275745807885387 0.0539080631377637 1.0 0.103643766740166 2 Q9P035 1 +Graves disease carrier protein [IPR002167] 0.8920525657071466 1.916494722420805 0.0553021543274763 1.0 0.1056493699984285 2 Q86VD7 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8767209011264081 1.848461443524963 0.0645356171505389 1.0 0.1176159775367444 2 Q9NVI7 1 +Short-chain dehydrogenase/reductase SDR [IPR002347] 0.5362884947438584 1.8318900179521072 0.066967808039871 1.0 0.1206955623412002 18 Q6UX07,Q8NBN7,Q9HBH5,Q8TC12,Q53GQ0,Q6YN16,Q8NBQ5,Q06136,Q9Y394,Q3SXM5,Q6IAN0 11 +Phosphatidylinositol transfer protein [IPR001666] 0.8692115143929915 1.8150376886807176 0.0695181178101358 1.0 0.1244893839219229 2 Q00169 1 +Membrane bound O-acyl transferase, MBOAT [IPR004299] 0.8673341677096491 1.806671852769361 0.0708134589028188 1.0 0.1262697821399661 2 Q96N66 1 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.8654568210262927 1.798302158291748 0.0721291379142177 1.0 0.1278553755385807 2 Q9NPH0 1 +Chloride channel, voltage gated [IPR001807] 0.8585732165206508 1.7675811159203498 0.077130957294053 1.0 0.1339839457713165 2 P51790 1 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.7600659176924804 1.7612628585559698 0.0781939233052531 1.0 0.1352136845608363 6 Q6P179,P09960,Q9UIQ6,Q9NZ08 4 +Tetraspanin/Peripherin [IPR018499] 0.9339593114240904 1.7451920629805462 0.080951442366105 1.0 0.1389316705273672 3 O60637,O43657 2 +Major facilitator superfamily [IPR011701] 0.8317018723880643 1.7312561948804064 0.0834060806176504 1.0 0.1416945974571292 4 Q96ES6,Q9H2V7 2 +Ergosterol biosynthesis ERG4/ERG24 [IPR001171] 0.8488735919900019 1.7242107342093052 0.0846698070266769 1.0 0.1434540299522687 2 Q14739 1 +Prenyltransferase subunit beta [IPR045089] 0.8476220275344319 1.7186079580803022 0.0856857816369294 1.0 0.144688205770815 2 P49356 1 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.9255086071987394 1.7114245628693652 0.087002766035148 1.0 0.1460515087077833 3 Q9Y282,Q96RQ1 2 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.8454317897371708 1.708799623916115 0.0874880724296591 1.0 0.1462600260707147 2 O75880 1 +Copper chaperone SCO1/SenC [IPR003782] 0.8454317897371708 1.708799623916115 0.0874880724296591 1.0 0.1462600260707147 2 O75880 1 +Mpv17/PMP22 [IPR007248] 0.9064162754303544 1.6349085322477563 0.1020682235822127 1.0 0.1636734547691825 3 P39210,Q567V2 2 +Lysosome-associated membrane glycoprotein [IPR002000] 0.8272841051314183 1.627373686404271 0.1036577566253602 1.0 0.1655891528059723 2 P11279 1 +Purine 5'-nucleotidase [IPR016695] 0.8266583229036428 1.6245613362704316 0.1042560610971046 1.0 0.1663337030566361 2 P49902 1 +Syntaxin [IPR045242] 0.7716880676479762 1.6217334647353665 0.1048604301644886 1.0 0.1670860305850877 5 O15400,O60499,Q9UNK0,Q13190 4 +P-type ATPase, subfamily IIB [IPR006408] 0.8188360450563188 1.5893846408938066 0.111973580028938 1.0 0.1752024423835872 2 P20020 1 +Aminopeptidase N-type [IPR034016] 0.7968065122103908 1.5842943484940768 0.1131267512954514 1.0 0.1761305112991063 4 Q6P179,Q9UIQ6,Q9NZ08 3 +SUN domain-containing protein 1-5 [IPR045119] 0.8125782227784897 1.561216180959641 0.1184727524179656 1.0 0.1818654332419777 2 O94901 1 +Tumour protein D52 [IPR007327] 0.8022528160200252 1.514694645143313 0.1298497511333978 1.0 0.1948133415931001 2 O43399 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.7584767173954176 1.4214090434252515 0.1551978789392885 1.0 0.2233855053840102 4 Q01105,P55209 2 +Proteasome B-type subunit [IPR023333] 0.6364986978188081 1.3957832150391765 0.1627797863883271 1.0 0.2320418937977513 7 P28074,P49721 2 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.8466353677621248 1.3938207189944511 0.1633717498836699 1.0 0.2324905671421457 3 P12236,P12235 2 +Small GTPase superfamily, SAR1-type [IPR006687] 0.7740926157697339 1.3876616311161505 0.165240104783128 1.0 0.2343540606732525 2 Q9NR31 1 +TAF15/EWS/TLS family [IPR034870] 0.8413145539906118 1.3722980046384177 0.1699706865555776 1.0 0.2391757535647838 3 P35637,Q92804 2 +Type 1 protein exporter [IPR039421] 0.7012214218602958 1.3103813991923097 0.1900668429447973 1.0 0.2591914237664554 5 Q9NUT2,O75027,P08183,Q03519 4 +Major facilitator, sugar transporter-like [IPR005828] 0.7559449311639767 1.3058110486959826 0.1916168218134646 1.0 0.260674973904662 2 Q7L0J3 1 +G-protein, gamma subunit [IPR001770] 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.2649964020647767 2 P63218 1 +Integral membrane protein EMC3/TMCO1-like [IPR002809] 0.7468710888610854 1.264935631935027 0.2058944029777478 1.0 0.2762828362090739 2 Q9UM00 1 +Tricarboxylate/iron carrier [IPR004686] 0.812206572769944 1.25455893890245 0.2096389172410679 1.0 0.2804101625616836 3 Q96NB2,Q6P4A7 2 +Ancient conserved domain protein family [IPR045095] 0.7384230287859779 1.2269292687917053 0.2198491766439203 1.0 0.289905937335484 2 Q8NE01 1 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.7321652065081508 1.1988166838089325 0.230599233784277 1.0 0.3004807991842391 2 Q9BTY2 1 +Glycoside hydrolase, family 29 [IPR000933] 0.7321652065081508 1.1988166838089325 0.230599233784277 1.0 0.3004807991842391 2 Q9BTY2 1 +Prolyl 4-hydroxylase [IPR045054] 0.7268460575719745 1.1749534289237225 0.2400133482199091 1.0 0.3098145463552239 2 O15460 1 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.7252816020024981 1.167941157832055 0.242830500815435 1.0 0.3123525255887702 2 Q9Y5J9 1 +HnRNP R/Q splicing factor [IPR006535] 0.789358372456967 1.1623175400118917 0.2451065044556331 1.0 0.3143159863457557 3 O60506,A0AV96 2 +Stromal interaction molecule [IPR037608] 0.7183979974968657 1.1371252580351587 0.2554859264017501 1.0 0.3239932413441549 2 Q13586 1 +Calcium uptake protein 1/2/3 [IPR039800] 0.7143304130162932 1.1189478558381596 0.2631623851975622 1.0 0.3314154912427573 2 Q9BPX6 1 +Bicarbonate transporter, eukaryotic [IPR003020] 0.7124530663329407 1.1105670460706571 0.2667547539737471 1.0 0.3345917208733643 2 Q9Y6M7 1 +NADH:cytochrome b5 reductase-like [IPR001834] 0.7033792240300474 1.0701459171778245 0.2845536336180201 1.0 0.350434137142897 2 Q9UHQ9 1 +HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380] 0.763346149306725 1.0577933586526316 0.2901496612868888 1.0 0.3552391960086677 3 P49902 1 +Kinesin light chain [IPR002151] 0.7566578892838478 1.0310460668479455 0.3025192175388649 1.0 0.3659318996768192 3 Q9H0B6 1 +Prohibitin [IPR000163] 0.6911764705882577 1.016046049774337 0.3096074582038128 1.0 0.3718245178237676 2 Q99623 1 +Ribosomal protein L22/L17 [IPR001063] 0.6811639549436926 0.9719215710189216 0.3310895675423229 1.0 0.3891881694604697 2 Q9NWU5 1 +Glutathione Transferase family [IPR040079] 0.4910649078870366 0.9416763036370612 0.3463583906382947 1.0 0.4002929310270784 10 Q13505,Q8TB36,Q9H7Z7 3 +Mitochondrial Rho GTPase [IPR021181] 0.6536295369211436 0.8521660305139337 0.3941219475998094 1.0 0.4414017876250727 2 Q8IXI2 1 +Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129] 0.7076682316118689 0.8376986128392581 0.4021999927168731 1.0 0.4473630334551958 3 Q99735,O14880 2 +Prenylated rab acceptor PRA1 [IPR004895] 0.7061032863849703 0.8316197143666922 0.4056236307151537 1.0 0.4496627881783593 3 O60831,O75915 2 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.704928689259588 0.8270619865699999 0.4082019286425273 1.0 0.4514444186657577 3 P28074 1 +Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434] 0.6454943679599607 0.8173307144036664 0.4137394588145655 1.0 0.4559651679270464 2 Q969T7 1 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.7021279122808483 0.816211596756118 0.4143791252902673 1.0 0.4560846852682772 3 P10619 1 +Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699] 0.6442428035043724 0.8119971906750749 0.4167932435035117 1.0 0.457926550504295 2 Q13868 1 +Flotillin family [IPR027705] 0.6426783479349103 0.8053403725188302 0.4206232903145204 1.0 0.4607262509496445 2 Q14254 1 +Luc7-related [IPR004882] 0.6395494367959932 0.7920611504602129 0.4283250212177489 1.0 0.4664167882334715 2 O95232 1 +Microtubule-associated protein RP/EB [IPR027328] 0.6260951188986289 0.7355212671567575 0.462022092717901 1.0 0.4915211777075006 2 Q15555 1 +Beta tubulin [IPR002453] 0.5912913348262101 0.7138479744784358 0.4753211905986509 1.0 0.5037523654364809 4 Q9BUF5,Q13885 2 +Tubulin [IPR000217] 0.5912913348262101 0.7138479744784358 0.4753211905986509 1.0 0.5037523654364809 4 Q9BUF5,Q13885 2 +Acyltransferase ChoActase/COT/CPT [IPR000542] 0.6602016299634423 0.6572702094163263 0.5110071881519049 1.0 0.5395275221947935 3 P23786 1 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.6550860719874629 0.6384094459081496 0.523207183668684 1.0 0.5517138617394841 3 Q9ULX6,O43823 2 +ClpA/B family [IPR001270] 0.5919899874843451 0.5971074817934561 0.5504356230246448 1.0 0.5796969558518235 2 Q15645 1 +Adaptor protein complex, sigma subunit [IPR016635] 0.5757196495619415 0.5341324550155735 0.593249896771789 1.0 0.6224423437355384 2 P53680 1 +FAM98 [IPR018797] 0.571964956195233 0.5199284924572806 0.6031134157070059 1.0 0.6309494195088677 2 Q8NCA5 1 +CTP synthase [IPR004468] 0.5666458072590649 0.5000324852728192 0.6170522037613626 1.0 0.644727302601158 2 Q9NRF8 1 +Plakophilin/Delta catenin [IPR028435] 0.5660200250312801 0.4977096764205366 0.6186886868260164 1.0 0.6456328229175684 2 O00192 1 +NudC family [IPR037898] 0.5628911138923541 0.486153509900704 0.6268583303506845 1.0 0.6528044532956632 2 Q8IVD9 1 +Inosine-5'-monophosphate dehydrogenase [IPR005990] 0.5588235294117533 0.4712776377774592 0.6374424826836103 1.0 0.6627294572032907 2 P12268 1 +Vesicle-associated membrane-protein-associated protein [IPR016763] 0.557884856070076 0.4678688569872056 0.6398783757227222 1.0 0.664712631427898 2 Q9P0L0 1 +Histone deacetylase family [IPR000286] 0.5397371714643182 0.4038465260483777 0.6863255808002564 1.0 0.7103229787303353 2 Q13547 1 +Histone deacetylase [IPR003084] 0.5397371714643182 0.4038465260483777 0.6863255808002564 1.0 0.7103229787303353 2 Q13547 1 +CPSF6/7 family [IPR034772] 0.5378598247809638 0.3974378228714862 0.6910446287454419 1.0 0.7149129465146101 2 Q8N684 1 +MRG [IPR008676] 0.5366082603253955 0.3931887473560802 0.6941800801406508 1.0 0.7178615214278165 2 Q9UBU8 1 +Adenylate kinase 3/4, mitochondrial [IPR028586] 0.5344180225281483 0.385798408396159 0.699645974139858 1.0 0.7229196184541612 2 Q9UIJ7 1 +Ribosome biogenesis protein Bms1/Tsr1 [IPR039761] 0.5234668335419144 0.3497423187129543 0.7265320911985129 1.0 0.7482418098466879 2 Q2NL82 1 +Prefoldin alpha-like [IPR004127] 0.5178347934918519 0.3318021948197022 0.7400386268611672 1.0 0.7615285010972175 2 Q99471 1 +Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100] 0.5162703379223932 0.3268940029519994 0.7437480570847776 1.0 0.7650327520953805 2 P00390 1 +Defective-in-cullin neddylation protein [IPR014764] 0.5604880813469122 0.3217296230459757 0.7476575341235452 1.0 0.7684257989603103 3 Q96GG9 1 +Cohesin subunit Scc3/SA [IPR039662] 0.5125156445556813 0.3152502868084432 0.7525716272368392 1.0 0.7731605610975449 2 Q8WVM7 1 +Tight junction protein ZO [IPR005417] 0.504693366708373 0.2916226280570496 0.7705751724197807 1.0 0.7900436568085445 2 Q9UDY2 1 +Ribosomal protein S5 [IPR000851] 0.5015644555694492 0.2824155867625559 0.7776248647281567 1.0 0.7962979892779986 2 P82675 1 +H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504] 0.4981226533166319 0.2724523802420551 0.7852742017604952 1.0 0.8034769791091525 2 Q9NY12 1 +Ribosomal protein L4/L1e [IPR002136] 0.4956195244054963 0.265316064730149 0.7907659899753163 1.0 0.8087671669828845 2 Q9BYD3 1 +DNA-directed RNA polymerase, subunit 2 [IPR015712] 0.4921777221526768 0.2556563032917631 0.7982162389353125 1.0 0.8157238250045679 2 P30876 1 +Developmentally regulated GTP-binding protein [IPR045001] 0.4918648310387845 0.2547869795560651 0.7988876322779708 1.0 0.8160784745478581 2 P55039 1 +Ribosomal protein S5/S7 [IPR000235] 0.4884230287859701 0.2453224814647796 0.8062067458186468 1.0 0.8225531924086437 2 Q9Y2R9 1 +Septin [IPR016491] 0.4434738513028119 0.2394648173235025 0.8107451746259391 1.0 0.8258231450911652 5 Q16181 1 +Erlin1/2 [IPR033294] 0.4780976220275227 0.2180250125679346 0.827409622968819 1.0 0.8404370655589619 2 O75477 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.4712140175218882 0.2007592735774545 0.8408868094931148 1.0 0.8534373588885343 2 O60884 1 +Ribosomal protein S2 [IPR001865] 0.457446808510623 0.16852223691835 0.866172451304627 1.0 0.8780378273498958 2 Q9Y399 1 +Sorting nexin-5/6/32 [IPR014637] 0.4543178973717039 0.1616283033763841 0.871598567489976 1.0 0.883182438906476 2 Q9UNH7 1 +Oxysterol-binding protein [IPR000648] 0.4167111466384482 0.1572486605300229 0.8750488797352547 1.0 0.8863216511328104 5 Q9BZF1,Q9H1P3 2 +Beta-catenin [IPR013284] 0.4427409261576813 0.1375283788298562 0.8906131627973015 1.0 0.9006361405136699 2 P35222 1 +Mesoderm induction early response protein/metastasis-associated protein [IPR040138] 0.4744913928012615 0.1130261265306512 0.9100098419566448 1.0 0.9187739816865644 3 O94776,Q13330 2 +KH domain-containing BBP-like [IPR045071] 0.4719874804381945 0.1083871972512905 0.9136885564181932 1.0 0.9221180938420273 3 Q07666,Q96PU8 2 +Small GTPase [IPR001806] 0.2633987811144224 0.1003567075542709 0.9200611385579784 1.0 0.9281771550167898 35 Q969Q5,P61026,Q9H0U4,P62820,Q6IQ22,P61019,O14966 7 +Arfaptin family [IPR030798] 0.4214643304130052 0.0990192876326041 0.9211229560463 1.0 0.9288758947545052 2 P53365 1 +Proteasome, subunit alpha/beta [IPR001353] 0.3083597458924663 0.097267927752422 0.9225136251452546 1.0 0.9299055612441748 14 P49721 1 +Proteasome activator PA28 [IPR009077] 0.4460093896713716 0.0652938043378905 0.947940075241846 1.0 0.9542958614794996 3 Q9UL46,P61289 2 +Clathrin adaptor, mu subunit [IPR001392] 0.4187793427230116 0.0297711324003509 0.9762495815650516 1.0 0.981712209119772 3 Q9BXS5,Q96CW1 2 +Chaperone DnaJ [IPR012724] 0.3893583724569718 0.0016453335135337 0.9986872143844918 1.0 1.0 3 O60884,P31689 2 +YTH domain containing protein [IPR045168] 0.3022528160200145 0.0001546855124629 0.9998765788183182 1.0 1.0 2 Q7Z739 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a57358498e7efc7b49d25ac875b3103884c62dc0 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1,4-alpha-glucan-branching enzyme [IPR037439]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S26 [IPR026140]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 15 [IPR042292]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6 [IPR041839]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-ribosylation/Crystallin J1 [IPR005502]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase protein 8, mammals [IPR039017]", "ATP synthase protein 8, metazoa [IPR001421]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin filament-associated protein 1 [IPR029907]", "Actin-filament associated protein [IPR030113]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 2/3 complex subunit 5 [IPR006789]", "Actin-related protein 3 [IPR015623]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active regulator of SIRT1 [IPR023262]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "Adenylyltransferase and sulfurtransferase MOCS3/Uba4 [IPR028885]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Ankyrin repeat and SAM domain-containing protein 1A [IPR033637]", "Ankyrin repeat domain-containing protein 13 [IPR021832]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 2 [IPR005293]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Atypical kinase COQ8B [IPR034638]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 9 [IPR007241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BBP/SF1 family [IPR031150]", "BCP1 family [IPR025602]", "BEN domain-containing protein 3 [IPR033583]", "BET1-like protein [IPR039897]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Bet3 family [IPR016721]", "Beta tubulin [IPR002453]", "Beta-1,4-galactosyltransferase [IPR003859]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biogenesis of lysosome-related organelles complex 1 subunit 1 [IPR009395]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 1 [IPR037351]", "COMM domain-containing protein 7 [IPR037358]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTD phosphatase Fcp1 [IPR039189]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Carboxymethylenebutenolidase homolog [IPR042946]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-2 [IPR035702]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cationic amino acid transport permease [IPR004755]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc42-interacting protein 4 [IPR028498]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-K [IPR020993]", "Centromere protein H [IPR040034]", "Centromere protein I [IPR012485]", "Centromere protein U [IPR025214]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 290kDa [IPR026201]", "Ceramide glucosyltransferase [IPR025993]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Ceroid-lipofuscinosis neuronal protein 6 [IPR029255]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Choline transporter-like [IPR007603]", "Choline/ethanolamine phosphotransferase [IPR014472]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homolog 2 [IPR042796]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 127 [IPR034607]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coilin [IPR024822]", "Complex I intermediate-associated protein 30, mitochondrial [IPR039131]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit G2 [IPR024741]", "Connexin [IPR000500]", "Conserved oligomeric Golgi complex subunit 8 [IPR007255]", "Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae [IPR016632]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclin/Cyclin-like subunit Ssn8 [IPR043198]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein CtaG/Cox11 [IPR007533]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35 [IPR028601]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase delta subunit 3 [IPR019038]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA recombination and repair protein, RecA-like [IPR016467]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication ATP-dependent helicase/nuclease Dna2 [IPR026851]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed DNA-polymerase, family A, mitochondria [IPR002297]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Decaprenyl diphosphate synthase-like [IPR001441]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxycytidylate deaminase [IPR016473]", "Deoxycytidylate deaminase-related [IPR015517]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxynucleoside kinase [IPR002624]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydroorotate dehydrogenase, class 2 [IPR005719]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 4 [IPR030612]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylarginine dimethylaminohydrolase [IPR033199]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Distrobrevin [IPR017432]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichol kinase [IPR026566]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-binding protein [IPR035469]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase PIAS2 [IPR027228]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF25 [IPR039133]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 10 [IPR029615]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosulphine [IPR006760]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-2 [IPR027673]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Eyes absent family [IPR028472]", "Eyes absent homologue 4 [IPR028478]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM105 [IPR023235]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FLYWCH-type zinc finger-containing protein 1/2 [IPR040312]", "FMP27 [IPR045167]", "FUN14 [IPR007014]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Folliculin [IPR021713]", "Forkhead box protein C1 [IPR033067]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GPN-loop GTPase 1 [IPR030230]", "GPN-loop GTPase [IPR004130]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GRIP1-associated protein 1 [IPR026204]", "GTP cyclohydrolase 1 type 2/Nif3 [IPR002678]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "GTP-binding protein, ribosome biogenesis [IPR019991]", "GTPase, MTG1 [IPR016478]", "Galactokinase [IPR000705]", "Gamma-adducin [IPR027772]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gap junction alpha-1 protein (Cx43) [IPR002261]", "Gem-associated protein 4 [IPR033265]", "Gemini of Cajal bodies-associated protein 8 [IPR034754]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Geranylgeranyl transferase type-2 subunit beta [IPR026873]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 4 (GLUT4) [IPR002441]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase family 29 [IPR001675]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 4 [IPR000715]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histidine-tRNA ligase [IPR015807]", "Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit [IPR004516]", "Histone H2A [IPR002119]", "Histone H3/CENP-A [IPR000164]", "Histone H4 [IPR001951]", "Histone PARylation factor 1 [IPR019361]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP130 [IPR024137]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase SETD2, animal [IPR042294]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "I-BAR domain containing protein MTSS1/MTSS2 [IPR030127]", "I-BAR domain containing protein MTSS2 [IPR030059]", "ICln [IPR003521]", "ING family [IPR028651]", "Impact family [IPR023582]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of growth protein 4/5 [IPR028638]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Innexin [IPR000990]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 1,4,5-trisphosphate receptor-interacting protein [IPR024797]", "Inositol 1,4,5-trisphosphate receptor-interacting protein family [IPR026250]", "Inositol monophosphatase-like [IPR000760]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integral membrane protein SYS1 [IPR016973]", "Integral membrane protein SYS1-related [IPR019185]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 10 [IPR026164]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 9 [IPR027074]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interferon-stimulated 20kDa exonuclease-like 2 [IPR034933]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intraflagellar transport protein 25 [IPR033558]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Keratin, type I [IPR002957]", "Keratinocyte-associated transmembrane protein 2 [IPR037645]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LIM domain only protein 7 [IPR029978]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte elastase inhibitor (serpin B1) [IPR015557]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase phosphoprotein 6 [IPR019324]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "MT-A70-like [IPR007757]", "Macrophage migration inhibitory factor [IPR001398]", "Magnesium transporter MRS2-like [IPR039204]", "Magnesium transporter protein 1 [IPR006844]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med18 [IPR019095]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membralin [IPR019144]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA formyltransferase [IPR005794]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microsomal glutathione S-transferase 1-like [IPR040162]", "Microtubule associated protein 1 [IPR026074]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein Mtm1-like [IPR045315]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial dynamics protein MID49/MID51 [IPR045909]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim10 [IPR027100]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase kinase kinase 7 [IPR017421]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitoguardin [IPR019392]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Mucosa-associated lymphoid tissue lymphoma translocation protein 1 [IPR033540]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin-related protein 14 [IPR039802]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 [IPR033202]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyltransferase II [IPR007754]", "N-acetyltransferase Ard1-like [IPR045047]", "N-acyl-L-amino-acid amidohydrolase [IPR010159]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "N6-adenosine-methyltransferase MT-A70-like [IPR025848]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-plastoquinone oxidoreductase, chain 5 subgroup [IPR018393]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain 5-like [IPR003945]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NIF3-like protein 1, animal [IPR017222]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Nectin-2 [IPR033318]", "Nesprin-2 [IPR030266]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neutral amino acid SLC6 transporter [IPR002438]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Nuclear RNA export factor [IPR030217]", "Nuclear RNA-splicing-associated protein, SR-25 [IPR019532]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear factor related to kappa-B-binding protein [IPR024867]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein GIPC1/2/3 [IPR017379]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "PSME3-interacting protein [IPR039845]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pannexin [IPR039099]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1C [IPR001940]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxin-3 [IPR006966]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal biogenesis factor 11 [IPR008733]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphatidylserine lipase ABHD16A [IPR026604]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphoserine phosphatase [IPR004469]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Platelet-activating factor acetylhydrolase, eucaryote [IPR016715]", "Platelet-activating factor acetylhydrolase-like [IPR005065]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyprenol kinase family [IPR032974]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Progesterone-induced-blocking factor 1 [IPR026205]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein C10 [IPR026317]", "Protein CIP2A [IPR042510]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein NCBP2AS2 [IPR042407]", "Protein NDRG3 [IPR030692]", "Protein O-mannose kinase [IPR039318]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PCF11-like [IPR045154]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sec13 [IPR037596]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein canopy homolog [IPR042415]", "Protein diaphanous homologue 2 [IPR027644]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein suppressor of sable-like [IPR045124]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein zyg-11 homologue B [IPR040367]", "Protein-L-histidine N-pros-methyltransferase [IPR007884]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA-binding protein 47 [IPR034442]", "Putative ribosome-binding factor A, mitochondrial [IPR039212]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "Queuosine salvage protein family [IPR019438]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RFT1 [IPR007594]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase, Rpb8 [IPR005570]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab12 [IPR041830]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "Raftlin family [IPR028169]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Rab29/Rab38/Rab32 [IPR030697]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulon-4-interacting protein 1 [IPR037397]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinoblastoma protein family [IPR028309]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retinoblastoma-like protein 1 [IPR028310]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho GDP/GTP exchange factor Kalirin/TRIO [IPR028570]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease P protein subunit Rpp38 [IPR042848]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S27/S33, mitochondrial [IPR013219]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding factor A [IPR000238]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SPRY domain-containing protein 7 [IPR035766]", "SSNA1 family [IPR033362]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sarcolemmal membrane-associated protein [IPR030498]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sialyltransferase [IPR012163]", "Sideroflexin-4 [IPR028825]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Slowmo/Ups family [IPR037365]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Sodium:neurotransmitter symporter [IPR000175]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-19 [IPR034908]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingolipid delta(4)-desaturase DES1 [IPR031196]", "Sphingolipid delta4-desaturase [IPR011388]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol regulatory element-binding protein cleavage-activating protein [IPR030225]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Store-operated calcium entry-associated regulatory factor [IPR009567]", "Stromal interaction molecule 1 [IPR030463]", "Stromal interaction molecule [IPR037608]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Sulphide quinone-reductase [IPR015904]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syntaxin [IPR045242]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TATA binding associated factor 15 [IPR034875]", "TATA-binding protein-associated factor Mot1 [IPR044972]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TFIIH subunit Tfb1/GTF2H1 [IPR027079]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM14 family [IPR005349]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TNF receptor-associated factor 2 [IPR027133]", "TNF receptor-associated factor TRAF [IPR043211]", "TNF receptor-associated factor TRAF, metazoa [IPR012227]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 21A/21B [IPR040364]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 15 [IPR042418]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor Spt20 [IPR021950]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor IID, subunit 13 [IPR003195]", "Transcription initiation factor TFIID subunit 5 [IPR037783]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription initiation factor TFIIE, beta subunit [IPR016656]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional enhancer factor, metazoa [IPR016361]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumor protein p53-inducible protein 11 [IPR028266]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-protein kinase, non-receptor Jak/Tyk2 [IPR016251]", "Tyrosine-protein kinase, non-receptor Jak1 [IPR020776]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm1/8 [IPR044642]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UDP-GlcNAc-dolichyl-phosphate GlcNAc phosphotransferase [IPR033895]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronosyl/UDP-glucosyltransferase [IPR002213]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquilin-1/2 [IPR028430]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquinone biosynthesis protein COQ9 [IPR012762]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin thioesterase otulin [IPR023237]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier 1 [IPR005375]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar ATPase assembly integral membrane protein Vma21 [IPR019013]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WASH complex subunit 3 [IPR019309]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "Yos1-like [IPR013880]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger ZZ-type and EF-hand domain-containing protein 1 [IPR040099]", "Zinc finger protein 131 [IPR027758]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc finger protein 830-like [IPR040050]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor GLE1-like [IPR012476]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB [IPR006463]", "tRNA-specific 2-thiouridylase [IPR004506]"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABHD12", "ABHD16A", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADA", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFG3L2", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALKBH5", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANKLE2", "ANKRD13A", "ANKS1A", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "API5", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP5", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC6", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP8", "ATPAF1", "ATPIF1", "ATXN2L", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BANF1", "BAP18", "BASP1", "BCAP31", "BCAS2", "BCCIP", "BCL2L13", "BCLAF1", "BEND3", "BET1", "BIRC6", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRIX1", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C19orf70", "C1QBP", "C1orf35", "C2CD2", "C2CD5", "C2orf49", "C5orf15", "C8orf33", "C9orf64", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASP2", "CBL", "CBR1", "CBX2", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC97", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC20", "CDC37", "CDC40", "CDC42", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CEBPZ", "CELF2", "CENPH", "CENPI", "CENPK", "CENPU", "CEP170", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CIAPIN1", "CIP2A", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG8", "COIL", "COLGALT1", "COMMD1", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXorf56", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAKD", "DCP1A", "DCPS", "DCTD", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHPS", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX29", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EFHD1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCI", "FAR1", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNTB", "FOXC1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GCAT", "GCLC", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGCX", "GGH", "GHDC", "GHITM", "GINS3", "GINS4", "GIPC1", "GJA1", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMFB", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRIPAP1", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDHD2", "HDHD5", "HEATR1", "HEBP1", "HECTD1", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFT27", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INTS1", "INTS10", "INTS13", "INTS14", "INTS3", "INTS5", "INTS9", "IPO4", "IPO5", "IRS4", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "JAGN1", "JAK1", "JPT2", "JUP", "KARS", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMF2", "LMO7", "LNPEP", "LNPK", "LONP1", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LSM12", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYSMD3", "LZIC", "MACF1", "MAGED2", "MAGT1", "MAK16", "MALT1", "MAN1A1", "MANF", "MAP1B", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED14", "MED16", "MED18", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METTL1", "METTL3", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGAT2", "MGEA5", "MGST1", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS3", "MOGS", "MORF4L1", "MORF4L2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17", "MPV17L2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL4", "MRPL40", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTDH", "MTFMT", "MTFP1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTOR", "MTR", "MTSS1L", "MTX1", "MTX2", "MXRA7", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA40", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF1", "NDUFAF3", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NELFCD", "NF1", "NFRKB", "NFS1", "NHP2", "NIF3L1", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRM", "NSA2", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH2", "PAK2", "PANK4", "PANX1", "PAPSS1", "PARG", "PARK7", "PARN", "PATL1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCF11", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6IP", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLD2", "POLD3", "POLE", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMK", "PON2", "POP1", "POR", "PPA1", "PPAN", "PPAT", "PPHLN1", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP5C", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPH", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB29", "RAB2A", "RAB31", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABAC1", "RABGGTA", "RABGGTB", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RAP2B", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBFA", "RBL1", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM47", "RBM5", "RBM8A", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REEP6", "RER1", "RETREG3", "REXO4", "RFC1", "RFT1", "RFTN1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RNASEH2A", "RNF2", "RNF25", "RNF40", "RNMT", "RNPEP", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTFDC1", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARAF", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP3", "SCAP", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SCRN3", "SDAD1", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A4", "SLC30A5", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLK", "SLMAP", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMG8", "SMIM12", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX19", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPNS1", "SPR", "SPRYD7", "SPTBN1", "SPTBN2", "SQLE", "SQOR", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "ST3GAL4", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STIM2", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT3H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYS1", "TAB1", "TACC3", "TAF15", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARS", "TARS2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TEAD1", "TECR", "TEFM", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMM10", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM14C", "TMEM160", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMOD3", "TMX2", "TNPO1", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53I11", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPT1", "TPX2", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC3", "TRAPPC4", "TRIM28", "TRIO", "TRIP10", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSPAN10", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC38", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUBGCP5", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBQLN1", "UBR4", "UBR7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFM1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRQ", "URB1", "UROD", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS13C", "VPS13D", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4B", "VPS51", "VPS53", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WBP11", "WDR12", "WDR18", "WDR33", "WDR4", "WDR41", "WDR46", "WDR74", "WDR82", "WDR91", "WFS1", "WIPI2", "WTAP", "XAB2", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YLPM1", "YME1L1", "YTHDC1", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZCCHC3", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF131", "ZNF326", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZNF830", "ZPR1", "ZRANB2", "ZW10", "ZYG11B", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCB7", "ABCB8", "ACOX1", "ACP6", "AK3", "AKAP8", "AKAP8L", "AP1M1", "AP2M1", "AP2S1", "APOO", "ARFIP2", "ARL6IP5", "ARVCF", "ATAD3A", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP6V0A1", "BCL2L13", "CEPT1", "CHST14", "CLCN3", "CLPTM1", "CNNM3", "COMT", "COX18", "CPSF7", "CPT2", "CTNNB1", "CTPS2", "CTSA", "CYB5R1", "CYP20A1", "DCUN1D1", "DHRS13", "DHRS7", "DHRS7B", "DNAJA1", "DNAJA2", "DRG2", "ERAP1", "ERAP2", "ERGIC2", "ERGIC3", "ERLIN1", "EXOSC2", "FAM98A", "FLOT2", "FNTB", "FUCA2", "FUS", "GAR1", "GDAP1", "GHITM", "GNG5", "GPAM", "GPR107", "GSR", "HACD3", "HDAC1", "HMOX1", "HSD17B11", "HSD17B12", 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a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..37618c5f7ea3c6d88a576a504e20a36dc05080f0 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier domain superfamily [IPR023395] 20 22 3.3235937464574183 0.0008886554871001 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 9.114910675581717e-09 1.0 0.0004434091565531 2.9106518471628107e-05 1.0265235930703095e-09 +Alpha/Beta hydrolase fold [IPR029058] 12 27 2.3602617288259378 0.0182620456160849 7.793689320388349 25.487864077669904 0.3803730368869525 0.1931612116461074 2.8504230618688027 2.5849355029363217 1.9090082785106757 0.2379814650369476 0.0424352463255198 0.0040269256520789 0.0257953084689971 0.0780890051531907 0.0148430138161315 +P-type ATPase, cytoplasmic domain N [IPR023299] 5 7 2.182020177268643 0.0291080436149202 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0498968875883284 1.0 0.1898352204968973 0.097689242801984 0.0196049214971061 +P-type ATPase, transmembrane domain superfamily [IPR023298] 5 7 2.182020177268643 0.0291080436149202 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.055809421126224 1.0 0.1975594178204269 0.1053546389470493 0.0228511399682266 +P-type ATPase, A domain superfamily [IPR008250] 5 7 2.182020177268643 0.0291080436149202 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0498968875883284 1.0 0.1898352204968973 0.097689242801984 0.0196049214971061 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..2fad21212e26e2d1c190fd74e1d6af349a454910 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 955, + "title": "Average number of proteins per term", + "value": 4.870157068062827 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6c520262f49bc39f475172885f5d48673db16f1c --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..845ffc098a12ca536a210dd7102dbc1f081cbc75 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,113 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier domain superfamily [IPR023395] 0.7399345695769532 3.3235937464574183 0.0008886554871001 0.5721759643400253 0.0290849579444613 22 Q00325,Q8TBP6,P12236,Q9HC21,Q02978,P12235,Q70HW3,Q86VD7,Q9H2D1,Q9H936,Q9BQT8,Q9UBX3,Q9BSK2,Q9NZJ7,Q6NUK1,O43808,Q9UJS0,P05141,O75746,Q9Y6C9 20 +Alpha/Beta hydrolase fold [IPR029058] 0.559265159071176 2.3602617288259378 0.0182620456160849 0.9999999773128389 0.0990923497918243 27 P50897,Q96JX3,P10619,Q4J6C6,Q9HB40,P42785,Q99487,Q8NCG7,Q8N2K0,P07099,Q6PIU2,Q9H6V9 12 +Haem oxygenase-like, multi-helical [IPR016084] 0.9868585732165204 2.3299541624760285 0.0198085738970283 0.9999999949660502 0.1028895745543876 2 P09601 1 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.800569000047712 2.182020177268643 0.0291080436149202 0.99999999999944 0.1252170344695893 7 Q9HD20,P05023,P20020,P98194,P16615 5 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.800569000047712 2.182020177268643 0.0291080436149202 0.99999999999944 0.1252170344695893 7 Q9HD20,P05023,P20020,P98194,P16615 5 +P-type ATPase, A domain superfamily [IPR008250] 0.800569000047712 2.182020177268643 0.0291080436149202 0.99999999999944 0.1252170344695893 7 Q9HD20,P05023,P20020,P98194,P16615 5 +CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130] 0.9064455569461892 1.98009299939216 0.0476930796490044 1.0 0.1686921891288862 2 Q9Y6K0 1 +Cytochrome P450 superfamily [IPR036396] 0.905819774718408 1.9773335292612144 0.0480039420705482 1.0 0.1687548617264289 2 Q6UW02 1 +Porin domain superfamily [IPR023614] 0.8891671884783854 1.9697386441382327 0.048868331634758 1.0 0.1698481020322045 4 Q9Y277,P45880,P21796 3 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.7018808777429528 1.9554830167285453 0.0505260859993395 1.0 0.1711078444303873 8 P28288,P08183,Q9NUT2,O75027,Q03519,O14678,P33527 7 +Rhomboid-like superfamily [IPR035952] 0.8479400671294806 1.9512079383433896 0.0510323150474121 1.0 0.1716051439094316 5 Q9H300,Q6NTF9,Q8NBM4 3 +LEM/LEM-like domain superfamily [IPR011015] 0.7858708058256585 1.8775281939581077 0.0604457368779356 1.0 0.1909765945654856 6 P42167,Q86XL3,P50402 3 +Ricin B-like lectins [IPR035992] 0.8278686525782437 1.8653880817992172 0.0621270267123574 1.0 0.1932615977534247 5 Q9UBG0,Q10472 2 +Chloride channel, core [IPR014743] 0.8585732165206508 1.7675811159203498 0.077130957294053 1.0 0.2260457175166284 2 P51790 1 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.7600659176924804 1.7612628585559698 0.0781939233052531 1.0 0.2262884750197476 6 Q6P179,P09960,Q9UIQ6,Q9NZ08 4 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.7600659176924804 1.7612628585559698 0.0781939233052531 1.0 0.2262884750197476 6 Q6P179,P09960,Q9UIQ6,Q9NZ08 4 +HAD-like superfamily [IPR036412] 0.5074279597107535 1.7516776669088283 0.0798292492001553 1.0 0.2291562548401158 22 P49902,Q9H857,Q9HD20,P05023,Q3ZCQ8,P20020,P98194,P16615 8 +HAD superfamily [IPR023214] 0.5074279597107535 1.7516776669088283 0.0798292492001553 1.0 0.2291562548401158 22 P49902,Q9H857,Q9HD20,P05023,Q3ZCQ8,P20020,P98194,P16615 8 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.9339593114240904 1.7451920629805462 0.080951442366105 1.0 0.2307720222675532 3 O60637,O43657 2 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.7539178160352003 1.733378447020052 0.0830284258344258 1.0 0.2356183281555013 6 O43169,O15173 2 +Isoprenoid synthase domain superfamily [IPR008949] 0.8397997496871219 1.6835585258076242 0.0922670197167498 1.0 0.2503267154247049 2 P37268 1 +Thioredoxin-like superfamily [IPR036249] 0.3971044658017718 1.6585726934793048 0.0972019280224929 1.0 0.2562751301963014 49 Q9Y2G8,P78417,Q96CS3,Q9H0U3,Q96JJ7,Q9Y320,O43396,Q8TB36,Q9H7Z7,Q8TED1,Q9H3N1,Q96J42,Q9H1E5,O75880 14 +SNARE [IPR010989] 0.7716880676479559 1.621733464735278 0.1048604301645075 1.0 0.2699237488062121 5 O15400,O60499,Q13190,O14653 4 +Alkaline-phosphatase-like, core domain superfamily [IPR017850] 0.8191489361702311 1.5907924637244188 0.1116562895569459 1.0 0.2741176260331192 2 Q5H8A4 1 +GOLD domain superfamily [IPR036598] 0.7855353788353014 1.536535000314336 0.1244072204602084 1.0 0.2919137482542975 4 Q9Y3B3,Q15363,Q9Y3A6 3 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.4785775817396068 1.503855294108085 0.1326186301826488 1.0 0.3051826309022401 21 Q9Y6N5,Q9UHG3,Q14534,Q8NBM8 4 +MFS transporter superfamily [IPR036259] 0.6461442191809414 1.443516830593465 0.1488749348078992 1.0 0.3280196000989044 7 Q96ES6,Q9H2V7,Q7L0J3 3 +NAP-like superfamily [IPR037231] 0.7584767173954176 1.4214090434252515 0.1551978789392885 1.0 0.3376172537289761 4 Q01105,P55209 2 +Bcl-2-like superfamily [IPR036834] 0.8474930570948431 1.3972896675797724 0.1623264816656868 1.0 0.3429969618395618 3 Q9BXK5 1 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.4606573542296614 1.3695465793971449 0.1708284851086885 1.0 0.3508412973737581 21 Q8N4A0,P15291,Q16739,Q10469,Q10472,Q13144 6 +Galactose-binding-like domain superfamily [IPR008979] 0.5662427208596303 1.3659946259255422 0.1719406501688365 1.0 0.3523676414404268 10 P08236,O43396,Q9Y375 3 +Regulatory factor, effector binding domain superfamily [IPR011256] 0.7684605757196515 1.362250931097988 0.1731187074598508 1.0 0.3540221961973394 2 Q9Y6I9 1 +EF-hand domain pair [IPR011992] 0.3680513704478815 1.34241275411829 0.1794622016002698 1.0 0.3613204215686217 52 O75071,Q9NWM8,Q6NUK1,Q9BPX6,Q9Y680,Q8NF37,O75340,O95202,Q14257,Q9BRK5,Q02818,P80303 12 +G-protein gamma-like domain superfamily [IPR036284] 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.3729639368176236 2 P63218 1 +Tim10-like domain superfamily [IPR035427] 0.7257357545397575 1.2814841714766183 0.2000236561145705 1.0 0.3790130785504262 4 Q9Y5J6,P62072,Q9Y5J9 3 +BSD domain superfamily [IPR035925] 0.7493742177722111 1.2762067725213837 0.2018824352034309 1.0 0.3810231731606256 2 P32780 1 +C-type lectin fold [IPR016187] 0.7954965700209482 1.1870696315211884 0.2352001558449448 1.0 0.4190599791640341 3 Q8NBJ7 1 +Ribokinase-like [IPR029056] 0.777863115477448 1.1160423563479962 0.2644040044740614 1.0 0.4506522401216527 3 Q9BRR6 1 +Band 7/SPFH domain superfamily [IPR036013] 0.5409384224768495 1.1152840968398925 0.264728698123819 1.0 0.4506522401216527 8 O75477,Q99623,P27105,Q14254 4 +Phosphotransferase/anion transporter [IPR016152] 0.7124530663329407 1.1105670460706571 0.2667547539737471 1.0 0.4517100467847831 2 Q9Y6M7 1 +C-type lectin-like/link domain superfamily [IPR016186] 0.7090112640801253 1.0952175225383345 0.2734213508036138 1.0 0.4593243733223799 2 Q9UBG0 1 +Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930] 0.7621283255085897 1.05291849880312 0.2923783470037251 1.0 0.4764868965675042 3 P53611,P49356 2 +Glycoside hydrolase superfamily [IPR017853] 0.4394722224073577 1.0494079749734733 0.2939903893151279 1.0 0.4774843908094338 16 P04062,P06865,O60502,P08236,P10253,P04066,Q9BTY2 7 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.635972534503285 1.019835908293462 0.3078062900315834 1.0 0.491240129610927 5 Q9BUF5,Q13885,Q9BUK6 3 +Histidine phosphatase superfamily [IPR029033] 0.6358245240049603 1.0191786626059791 0.30811815459366 1.0 0.491240129610927 5 Q9NPH0 1 +Ribosomal protein L22/L17 superfamily [IPR036394] 0.6811639549436926 0.9719215710189216 0.3310895675423229 1.0 0.5124644035703702 2 Q9NWU5 1 +Zinc finger, CCHC-type superfamily [IPR036875] 0.6670838548185173 0.9103585529290276 0.3626334483933986 1.0 0.5255158470647886 2 Q9NUD5 1 +Riboflavin synthase-like beta-barrel [IPR017938] 0.7154828048363391 0.8681605642288709 0.3853064395701913 1.0 0.5489697025244165 3 P16435 1 +Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261] 0.7154828048363391 0.8681605642288709 0.3853064395701913 1.0 0.5489697025244165 3 P16435 1 +Alpha/beta knot methyltransferases [IPR029028] 0.6511264080100048 0.8414174141645335 0.4001141331340303 1.0 0.5610998489618193 2 Q13395 1 +tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026] 0.6511264080100048 0.8414174141645335 0.4001141331340303 1.0 0.5610998489618193 2 Q13395 1 +Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352] 0.7076682316118689 0.8376986128392581 0.4021999927168731 1.0 0.5611874801595749 3 Q99735,O14880 2 +Ribosomal protein L37ae/L37e [IPR011331] 0.6439299123904799 0.8106649249428234 0.4175581211710231 1.0 0.5680455921913491 2 P61927 1 +START-like domain superfamily [IPR023393] 0.583958231526467 0.790970504624427 0.4289612035994246 1.0 0.5771176161475615 5 Q9NQZ5,Q00169 2 +EB1, C-terminal domain superfamily [IPR036133] 0.6260951188986289 0.7355212671567575 0.462022092717901 1.0 0.6048474851389617 2 Q15555 1 +Fibronectin type II domain superfamily [IPR036943] 0.6786476905821646 0.7263160077653008 0.467645068201648 1.0 0.6058178063729593 3 Q9UBV2 1 +Kringle-like fold [IPR013806] 0.6786476905821646 0.7263160077653008 0.467645068201648 1.0 0.6058178063729593 3 Q9UBV2 1 +Tubulin/FtsZ, C-terminal [IPR008280] 0.5912913348262101 0.7138479744784358 0.4753211905986509 1.0 0.6058178063729593 4 Q9BUF5,Q13885 2 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.5912913348262101 0.7138479744784358 0.4753211905986509 1.0 0.6058178063729593 4 Q9BUF5,Q13885 2 +Tubulin, C-terminal [IPR023123] 0.5912913348262101 0.7138479744784358 0.4753211905986509 1.0 0.6058178063729593 4 Q9BUF5,Q13885 2 +NAD(P)-binding domain superfamily [IPR036291] 0.3116362421455332 0.7131719865372645 0.4757393386791038 1.0 0.6058178063729593 65 Q8NBN7,Q658P3,Q9HBH5,Q8WWV3,P00367,Q16836,Q8NBX0,Q53GQ0,Q8N4Q0,Q8NBQ5,P40939,Q13423,Q06136,Q9Y394,Q3SXM5,Q9NRG7 16 +ANL, N-terminal domain [IPR042099] 0.4979630209965758 0.7060326328835148 0.4801678439725332 1.0 0.6097876210023527 7 O14975,O95573,O60488,Q6P1M0,Q9P265,P33121 6 +Choline/Carnitine o-acyltransferase, domain 2 [IPR042231] 0.6602016299634423 0.6572702094163263 0.5110071881519049 1.0 0.6362605797719286 3 P23786 1 +Dimeric alpha-beta barrel [IPR011008] 0.6556681470432768 0.6405487566424775 0.5218159018908619 1.0 0.6488726384189754 3 O75323 1 +Six-hairpin glycosidase superfamily [IPR008928] 0.6503912363067312 0.621219922788617 0.5344549327648624 1.0 0.6628629360914853 3 P46020,P35573 2 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.5913642052565611 0.5946448872837522 0.5520808687392531 1.0 0.6787910777727754 2 P35611 1 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.3622390127135699 0.5883680078214895 0.5562853065851256 1.0 0.6828437889316131 17 Q13505,Q8TB36,Q9H7Z7,P78417 4 +Chaperone J-domain superfamily [IPR036869] 0.3602096337089302 0.5763860223695468 0.5643542900518601 1.0 0.690087512163286 19 Q96KC8,Q9NVH1,Q9Y2G8 3 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.5302273215518891 0.5633889718092184 0.5731700450978714 1.0 0.6981854503424326 5 Q9NS86,O43399 2 +Acyl-CoA binding protein superfamily [IPR035984] 0.6229708820781936 0.5233947173665091 0.6006995995873972 1.0 0.7157933648813325 3 Q5T8D3 1 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.5972557933451974 0.4363467198886537 0.6625851895109509 1.0 0.771669336564583 3 P04439 1 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.5972557933451974 0.4363467198886537 0.6625851895109509 1.0 0.771669336564583 3 P04439 1 +AMP-binding enzyme, C-terminal domain superfamily [IPR045851] 0.4976511118070921 0.4335125955634912 0.66464241758562 1.0 0.7731224224047103 5 O60488,Q9P265,Q6P1M0,O14975 4 +FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156] 0.5165936130244273 0.425297910131737 0.6706195168493947 1.0 0.7770060221215013 4 O95831,Q16881,P00390 3 +MoaB/Mog-like domain superfamily [IPR036425] 0.5406758448059955 0.4070665306284998 0.6839591245806642 1.0 0.786018007189572 2 Q9NQX3 1 +Histone deacetylase domain superfamily [IPR037138] 0.5397371714643182 0.4038465260483777 0.6863255808002564 1.0 0.7877895789233713 2 Q13547 1 +BRO1 domain superfamily [IPR038499] 0.5369211514392908 0.3942492511833922 0.6933970269186907 1.0 0.7929927948975138 2 Q8WUM4 1 +MRG, C-terminal domain superfamily [IPR038217] 0.5366082603253955 0.3931887473560802 0.6941800801406508 1.0 0.7929927948975138 2 Q9UBU8 1 +Adenylate kinase, active site lid domain superfamily [IPR036193] 0.5344180225281483 0.385798408396159 0.699645974139858 1.0 0.7982818462408175 2 Q9UIJ7 1 +K homology domain superfamily, prokaryotic type [IPR009019] 0.5253441802252703 0.3558149525407394 0.7219791504654336 1.0 0.8150001048398217 2 O75616 1 +Longin-like domain superfamily [IPR011012] 0.3682634703032242 0.3410094895806615 0.7330964378228262 1.0 0.8226875418575781 12 P48444,Q9BXS5,Q9Y296,P61923,O75396,P53680,O15498 7 +DCN1-like, PONY binding domain [IPR042460] 0.5604880813469122 0.3217296230459757 0.7476575341235452 1.0 0.831965727501619 3 Q96GG9 1 +PapD-like superfamily [IPR008962] 0.5580594679186307 0.3146264965964742 0.753045258764006 1.0 0.8362304908367741 3 Q8NHP6,Q9P0L0 2 +L27 domain superfamily [IPR036892] 0.480588603631811 0.3021390354044653 0.7625460761823899 1.0 0.8418861303516559 4 Q9NZW5,Q14168,O14936 3 +SCP2 sterol-binding domain superfamily [IPR036527] 0.544913928012527 0.2772857684576214 0.7815606864200255 1.0 0.8579200638288786 3 P51659,Q6YN16 2 +H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664] 0.4981226533166319 0.2724523802420551 0.7852742017604952 1.0 0.8610067309773513 2 Q9NY12 1 +Ribosomal protein L4 domain superfamily [IPR023574] 0.4956195244054963 0.265316064730149 0.7907659899753163 1.0 0.8640520828677655 2 Q9BYD3 1 +RNA polymerase Rpb2, domain 2 superfamily [IPR037034] 0.4921777221526768 0.2556563032917631 0.7982162389353125 1.0 0.8652627788685849 2 P30876 1 +RNA polymerase Rpb2, OB-fold [IPR014724] 0.4921777221526768 0.2556563032917631 0.7982162389353125 1.0 0.8652627788685849 2 P30876 1 +DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033] 0.4921777221526768 0.2556563032917631 0.7982162389353125 1.0 0.8652627788685849 2 P30876 1 +Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100] 0.3625722732293469 0.249466892533119 0.8029996474095027 1.0 0.8684764023511609 10 Q15067,O15254 2 +Acyl-CoA dehydrogenase-like, C-terminal [IPR036250] 0.3625722732293469 0.249466892533119 0.8029996474095027 1.0 0.8684764023511609 10 Q15067,O15254 2 +Ribosomal protein S7 domain superfamily [IPR036823] 0.4884230287859701 0.2453224814647796 0.8062067458186468 1.0 0.8709586450868866 2 Q9Y2R9 1 +p53-like tetramerisation domain superfamily [IPR036674] 0.4806007509386667 0.224489797971451 0.8223762043979781 1.0 0.8854219562571242 2 P04637 1 +Zinc-binding ribosomal protein [IPR011332] 0.5183098591549382 0.2078193577087813 0.8353700173218379 1.0 0.8950515380712988 3 P61513,P61927 2 +Prefoldin [IPR009053] 0.5179968701095551 0.2070534360049751 0.8359681267005423 1.0 0.8950515380712988 3 Q9UHV9,Q99471 2 +S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] 0.2835397096302194 0.2070046162207946 0.8360062533608361 1.0 0.8950515380712988 32 Q86VU5,Q86X55,Q08J23,P21964,Q9BV86,Q9H1A3,Q6UX53 7 +Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591] 0.457446808510623 0.16852223691835 0.866172451304627 1.0 0.9180851176425292 2 Q9Y399 1 +UBA-like superfamily [IPR009060] 0.2990591009066828 0.1619626586086144 0.8713352596738466 1.0 0.9221525642906092 21 Q8NBM4,Q96CS3,Q9BSL1,Q9UPU5,Q9UMX0 5 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.3742777790048038 0.1611933535506444 0.8719411157637906 1.0 0.9221525642906092 7 Q13423,Q8IXJ6 2 +Oxysterol-binding protein superfamily [IPR037239] 0.4167111466384482 0.1572486605300229 0.8750488797352547 1.0 0.9223749228997442 5 Q9BZF1,Q9H1P3 2 +6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927] 0.3480619768135575 0.1486772862248411 0.8818082849775153 1.0 0.9274525464245894 8 P40939 1 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.4189104571070695 0.1278408269337856 0.8982749399077719 1.0 0.9375437897398056 4 P48444,Q9BXS5,Q96CW1 3 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.2913519512942943 0.1172585899436229 0.906655139029506 1.0 0.9442264534058648 17 P49721 1 +Proteasome activator superfamily [IPR036252] 0.4460093896713716 0.0652938043378905 0.947940075241846 1.0 0.978473587253032 3 Q9UL46,P61289 2 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.4460093896713716 0.0652938043378905 0.947940075241846 1.0 0.978473587253032 3 Q9UL46,P61289 2 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.4460093896713716 0.0652938043378905 0.947940075241846 1.0 0.978473587253032 3 Q9UL46,P61289 2 +HSP40/DnaJ peptide-binding [IPR008971] 0.3637218045112881 0.0624179958596962 0.9502299642783132 1.0 0.978473587253032 6 Q96EY1,Q9UBS4,Q9UDY4,O60884,P31689 5 +C2 domain superfamily [IPR035892] 0.2836897457418684 0.0616897081137431 0.950809936095093 1.0 0.978473587253032 18 Q96PU5,Q9UGP8 2 +Glycosyl hydrolase, all-beta [IPR013780] 0.3078863492522446 0.0101023693841749 0.991939612545398 1.0 1.0 9 Q16706,P10253,Q9BTY2 3 +ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034] 0.3222778473091236 0.006316921146212 0.9949598596655178 1.0 1.0 2 P06576 1 +Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410] 0.3893583724569718 0.0016453335135337 0.9986872143844918 1.0 1.0 3 O60884,P31689 2 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f3fc77901f64acc200769b448fa82d7c51ae8bd3 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "ADP-ribosylation/Crystallin J1 superfamily [IPR036705]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Actin-related protein 2/3 complex subunit 5 superfamily [IPR036743]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-dystroglycan domain 2 [IPR027468]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "BolA-like superfamily [IPR036065]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Connexin, C-terminal [IPR034634]", "Connexin, N-terminal domain superfamily [IPR038359]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily [IPR023471]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase delta subunit 3 superfamily [IPR041913]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Decaprenyl diphosphate synthase-like superfamily [IPR036424]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Deoxyhypusine synthase superfamily [IPR036982]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "EYA domain superfamily [IPR038102]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavin prenyltransferase-like [IPR036551]", "Flavoprotein-like superfamily [IPR029039]", "Folliculin, DENN domain, C-terminal superfamily [IPR044886]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GLE1-like superfamily [IPR038506]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GT29-like superfamiliy [IPR038578]", "GTF2I-like repeat superfamily [IPR036647]", "GTP cyclohydrolase 1 type 2/Nif3 superfamily [IPR036069]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gap junction alpha-1 protein (Cx43), alpha helix domain superfamily [IPR035091]", "Gelsolin-like domain superfamily [IPR036180]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Helix hairpin bin domain superfamily [IPR029012]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Impact, N-terminal domain superfamily [IPR036956]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NFRKB winged helix-like domain superfamily [IPR038106]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PBDC1-like domain superfamily [IPR023139]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribosome-binding factor A domain superfamily [IPR023799]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Set2 Rpb1 interacting domain superfamily [IPR038190]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Sodium:neurotransmitter symporter superfamily [IPR037272]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfatase-modifying factor enzyme superfamily [IPR042095]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEA/ATTS domain superfamily [IPR038096]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIID subunit TAF5, NTD2 domain superfamily [IPR037264]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "AMFR", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATXN10", "AURKA", "B4GALT1", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BAZ1A", "BAZ1B", "BCKDHB", "BCL2L12", "BCL2L13", "BCS1L", "BIRC6", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD2", "C2CD5", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPV", "CEP170", "CEPT1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHRAC1", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT9", "CNP", "COA7", "COASY", "COG8", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "COQ8B", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHDDS", "DHFR", "DHODH", "DHPS", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC19", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK7", "DOHH", "DOLPP1", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAM129B", "FAR1", "FARSA", "FARSB", "FASN", "FBL", "FBXO21", "FBXO22", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP4", "FNDC3A", "FNTB", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCX", "GGH", "GIGYF2", "GINS3", "GINS4", "GIPC1", "GJA1", "GLA", "GLB1", "GLDC", "GLE1", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLPH3", "GOPC", "GORASP2", "GOSR2", "GOT1", "GOT2", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INF2", "ING5", "INTS1", "INTS11", "INTS14", "INTS4", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISG20L2", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITGB1", "ITPA", "IVD", "IWS1", "JAK1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LACTB", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LDAH", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "MACF1", "MAGED2", "MAGT1", "MALT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED16", "MED21", "MEPCE", "METTL1", "METTL3", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGAT2", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL4", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTCH2", "MTFMT", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCKIPSD", "NCL", "NCOA5", "NCOR1", "NDC80", "NDRG3", "NDUFA10", "NDUFA9", "NDUFAF1", "NDUFAF3", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4L", "NEK9", "NENF", "NF1", "NFATC2IP", "NFRKB", "NFS1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCMT1", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PIAS2", "PICALM", "PIGG", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMK", "PON2", "POR", "PPA1", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB29", "RAB2A", "RAB31", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP7", "RBFA", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM47", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNF2", "RNF25", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTN4IP1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SCAF4", "SCAF8", "SCAP", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDAD1", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A4", "SLC30A5", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMS", "SMU1", "SMYD3", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX17", "SNX19", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "ST3GAL4", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STEAP3", "STIM1", "STIM2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STUB1", "STX10", "STX12", "STX5", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUPT16H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TAF15", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TEAD1", "TECR", "TEFM", "TELO2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFRC", "THEM6", "THOC1", "THOC3", "THOC6", "THOP1", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM10B", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM14C", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPT1", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC3", "TRAPPC4", "TRIM13", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIO", "TRIP10", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPAN10", "TSPAN3", "TSPAN6", "TSPYL1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUBGCP5", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFM1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS13D", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZCCHC3", "ZFR", "ZFYVE16", "ZMYND8", "ZNF131", "ZNF281", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZNF830", "ZPR1", "ZRANB2", "ZYG11B", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABHD12", "ACBD5", "ACOX1", "ACOX3", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ADD1", "ADPGK", "AGL", "AIFM1", "AK3", "ANKLE2", "AP1M1", "AP2M1", "AP2S1", "ARCN1", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1", "ATP5B", "B4GALT1", "BCL2L13", "CARM1", "CASK", "CEPT1", "CLCN3", "COMT", "COMTD1", "COPZ1", "CPT2", "CTSA", "CYB5B", "CYP20A1", "DAGLB", "DCUN1D1", "DHRS7", "DIP2B", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC11", "DNAJC16", "EFCAB14", "EIF2B5", "EMD", "EPHX1", "ERAL1", "ERAP1", "ERAP2", "ERLIN1", "FAF2", "FDFT1", "FKBP14", "FKBP7", "FLOT2", "FNTB", "FUCA1", "FUCA2", "GAA", "GALNT1", "GALNT4", "GAR1", "GBA", "GDAP1", "GLUD1", "GNG5", "GOSR2", "GPHN", "GPX8", "GSR", "GSTO1", "GTF2H1", "GUSB", "HADH", "HADHA", "HDAC1", "HEXA", "HLA-A", "HMOX1", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "KDSR", "LANCL2", "LDAH", "LETM1", "LNPEP", "LPCAT1", "LTA4H", "MAGT1", "MAN2A1", "MAPRE2", "METTL7B", "METTL9", "MFSD3", "MGAT2", "MGEA5", "MGST2", "MGST3", "MICU1", "MORF4L1", "MOSPD2", "MPP2", "MPP6", "MRC2", "MRPL22", "MRPL4", "MRPS2", "MRPS7", "MSTO1", "MTCH1", "MTCH2", "MTX1", "NAP1L1", "NCEH1", "NDUFAF1", "NEDD4L", "NIPSNAP2", "NNT", "NSUN2", "NT5C2", "NT5DC2", "NTMT1", "NUCB1", "NUCB2", "OSBPL2", "OSBPL8", "PAFAH2", "PARL", "PCYOX1", "PCYOX1L", "PDCD6", "PDCD6IP", "PFDN2", "PFDN5", "PGRMC2", "PHB2", "PHKA1", "PIGG", "PITPNA", "POLR2B", "POR", "PPT1", "PRCP", "PREPL", "PSMB2", "PSME2", "PSME3", "PTGES2", "RABGGTB", "RCN2", "RDH13", "RDH14", "RHBDD2", "RPL37", "RPL37A", "RTN4IP1", "SCCPDH", "SCO1", "SCPEP1", "SDF4", "SDR39U1", "SEC22B", "SEC63", "SEL1L", "SERAC1", "SET", "SIRT2", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC4A7", "SPNS1", "SQLE", "SQOR", "STARD7", "STEAP3", "STOM", "STX10", "STX5", "STX7", "SUMF2", "SV2A", "TAP2", "TARBP1", "TEX264", "TIMM10", "TIMM10B", "TIMM50", "TIMM8B", "TMED2", "TMED5", "TMED7", "TMPO", "TMX1", "TMX2", "TMX3", "TMX4", "TP53", "TPD52L2", "TRAPPC4", "TSPAN3", "TSPAN6", "TUBB2A", "TUBB6", "TXNDC15", "TXNL1", "TXNRD1", "UBAC1", "UBAC2", "UBQLN1", "UGCG", "USP24", "VAPA", "VDAC1", "VDAC2", "VDAC3", "YKT6", "ZADH2", "ZCCHC3"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6b2b1d3e31851c6905a093a9239a9bf9fdb4ccf5 --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "P-type ATPase, phosphorylation site [IPR018303]"} \ No newline at end of file diff --git a/interpro_ptm/advanced/plot_0.png b/interpro_ptm/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2b5ea60a6b1932191228c6a83d531641fba5d40f --- /dev/null +++ b/interpro_ptm/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:085ca6d861e2bca838cf7b5169cc55ad003885b87b2ed23acbfe32986a911463 +size 168203 diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6b2b1d3e31851c6905a093a9239a9bf9fdb4ccf5 --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "P-type ATPase, phosphorylation site [IPR018303]"} \ No newline at end of file diff --git a/interpro_ptm/basic/plot_0.png b/interpro_ptm/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..9574c1c20d72e1413c2110e30756306859423948 --- /dev/null +++ b/interpro_ptm/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b2a398456cfd57ac51d6865140cf14ebdff3a615d889f157c8114816efc3280d +size 140607 diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..18db540bcce7ffdec9f080359bca43ca2501e6bc --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fe43250d779d0455132d6c54cf79a73c8fc66f72cacf1e39439c6386e85a72e5 +size 71378 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..eacbb2dfee853c10639289666ba06c18ec48a819 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +P-type ATPase, phosphorylation site [IPR018303] 5 7 2.182020177268643 0.0291080436149202 2.941747572815534 6.145631067961165 0.9567723497044874 0.2732808833570771 1.8358630293390923 1.459204245106796 1.2102525517005158 0.2943240638910574 0.0498968875883284 1.0 0.1898352204968973 0.097689242801984 0.0196049214971061 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b14acf5798eb3854008dd9a82bc9eeaef0d8fd58 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.75 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e0e4e37055e7cdf6d1c4c3cf876354a9982a4ad6 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..945fc8159da0410b64fd23390a8e54480faa7755 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.800569000047712 2.182020177268643 0.0291080436149202 0.1114464378043568 0.0992410899832147 7 Q9HD20,P05023,P20020,P98194,P16615 5 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5c0738a722fb9e4bd97114e2f7a90b2e73230f81 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "EIF5A", "FASN", "LDLR", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2C1"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b046dd02ca0f764a13d1ea62193a247732fd8f01 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4177e9203ee28401dd06ad1f990fee091b7990081aca99c9c26c382aaa382422 +size 185576 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..69f984828be0adebcdc3bf1ff2ee606194f4f1a2 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:158e7e8624d06bbbc8a0f21b39a3a0b9137210d9603c8592bb8e40d4b2971266 +size 149129 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0723e4ee40b323ca7694cb63d9b758263331ef8d --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b7a7bbc32e37bc1d53b386b4ddb60fa3f8bafb21959fbe53266f4e00400eec08 +size 82701 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2b1288f1b7873eba7713bd937ac280bd185824ab --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 20 22 3.3235937464574183 0.0008886554871001 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 9.114910675581717e-09 1.0 0.0004434091565531 2.9106518471628107e-05 1.0265235930703095e-09 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cc16a1a92a03b0abdb2b07a592a36de0e2218a02 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 76, + "title": "Average number of proteins per term", + "value": 5.552631578947368 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..35e25fc2867f95c3ec2f543ee096d1a2da42b594 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..37ebb4c66f122442f97bb6e68c8da62448c8d08a --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.7399345695769532 3.3235937464574183 0.0008886554871001 0.0653356926532877 0.0142721843841028 22 Q00325,Q8TBP6,P12236,Q9HC21,Q02978,P12235,Q70HW3,Q86VD7,Q9H2D1,Q9H936,Q9BQT8,Q9UBX3,Q9BSK2,Q9NZJ7,Q6NUK1,O43808,Q9UJS0,P05141,O75746,Q9Y6C9 20 +PFTB repeat [IPR001330] 0.8476220275344319 1.7186079580803022 0.0856857816369294 0.9988952704177636 0.1588321805952837 2 P49356 1 +Sel1-like repeat [IPR006597] 0.8044430538172889 1.52456679605234 0.1273671845090942 0.9999681435710306 0.2151090227264702 2 Q9UBV2 1 +Kinesin light chain repeat [IPR015792] 0.7566578892838478 1.0310460668479455 0.3025192175388649 0.9999999999987164 0.4105617952313167 3 Q9H0B6 1 +HEAT repeat associated with sister chromatid cohesion protein [IPR026003] 0.4834167709636918 0.2318801533197512 0.8166310998030055 1.0 0.8741403321834988 2 Q96HW7 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..124db32ac3bf781e1322be61805afc21746d8eeb --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKRD13A", "ANKRD17", "ANKS1A", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC6", "ARMCX3", "ARPC1A", "ARPC1B", "ARVCF", "ASPH", "BIRC6", "BOP1", "BRAT1", "BUB3", "CDC20", "CDC23", "CDC27", "CDC40", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", 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+Cation transport 62 160 4.071195888383057 4.677239577888237e-05 40.9247572815534 152.4733009708738 1.0106305648473772 0.4693050539746304 15.98502541638414 15.374508146736815 1.5607432077940149 0.4143686874753333 6.102839207911117e-06 0.6973490707051213 0.1002618745075983 0.0009208749663371 1.2438137045535945e-06 +Organophosphate ester transport 20 33 3.976984094736497 6.97948313925778e-05 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 5.152883476830426e-09 1.0 0.1731294929006003 0.011900491094562 8.115162979844002e-11 +Mitochondrial transmembrane transport 38 54 3.940872676517309 8.118571251825024e-05 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 3.180745356375291e-10 0.3371313972628795 0.0086609949738754 0.000199462708587 6.725078155348949e-12 +Glycoprotein metabolic process 37 72 3.930665045948961 8.471121898900869e-05 18.59223300970874 59.577669902912625 0.8707431654759812 0.409720724299967 7.543964208858723 9.989377193127202 1.488085349392555 0.3835029669336279 5.301010954611446e-05 0.0942961333107097 0.0206171681935253 0.003278514197237 4.124003725200902e-07 +Cation transmembrane transport 53 124 3.923708360627992 8.719628300957183e-05 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 6.196801272310902e-06 0.8404776653133568 0.145506847798498 0.004134868400535 6.490559323941671e-07 +Endoplasmic reticulum organization 25 54 3.9041833667701695 9.454408065923126e-05 14.91747572815534 43.67718446601942 1.1418424810127707 0.3725584991544436 6.208589840117394 4.768440325801463 1.6823827875834556 0.3705219831566139 4.2242442600881706e-12 0.0057337308923017 0.0007612924156222 2.843075512931201e-09 4.976902704948527e-13 +Inorganic ion transmembrane transport 53 120 3.8998502532129775 9.625220144870994e-05 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 6.937347419911198e-06 0.4929961271860759 0.0160285035525861 0.0038168658945258 1.614734434100082e-07 +Glycoprotein biosynthetic process 33 62 3.89928053747346 9.647893975484044e-05 16.72087378640777 51.87378640776699 1.042113998842759 0.381483262234126 6.756316800759528 8.908847583990125 1.5232206853916193 0.3819786061588057 0.0001195196244273 0.2319080516082868 0.0347075013950788 0.0063206385106294 4.512935433219813e-06 +Endomembrane system organization 58 183 3.881545347058911 0.0001037947922171 47.08980582524272 169.73058252427185 0.8987911429216844 0.5600148744834964 15.914797198368843 20.49740065572335 1.4161383035869868 0.4170367608227654 6.255939071007501e-11 0.1143079274466006 0.0112182696845075 2.0653608644095336e-05 3.459874966420621e-12 +Organic acid transmembrane transport 26 32 3.859776599774676 0.000113490731072 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 4.738570120138696e-05 1.0 0.1765294646149295 0.1274569302589828 2.46849940364392e-05 +Mitochondrial respiratory chain complex assembly 26 45 3.819528284905671 0.0001337071275064 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 7.563269597219877e-09 7.092195860576647e-05 1.805768624943815e-07 3.202092673767345e-08 2.1546790475184758e-10 +Mitochondrial membrane organization 28 51 3.8036854568923366 0.0001425591754584 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 1.1057046990273085e-07 0.0011305823171669 3.34202046913148e-06 6.443185592583988e-08 6.522984310891191e-10 +Mitochondrial transport 38 88 3.7484720349494727 0.0001779151706333 26.76456310679612 83.42233009708738 1.9353944346565397 0.260698067067068 11.29934298946582 6.8259418360610375 1.9296757414965091 0.3685496297416806 7.47581700432989e-12 0.0086425657709555 3.126946860060388e-05 2.2635304259711973e-08 1.8963068028158048e-11 +Sphingolipid metabolic process 18 33 3.710689877498325 0.000206695194223 12.631067961165048 29.174757281553397 1.3566630100256978 0.1614907042591146 4.986857078326301 3.461093559903884 2.232073980338918 0.2503191978902473 4.609552147903114e-07 0.0748187401998431 0.0122290647268822 2.463765146783068e-06 2.1117790580603235e-06 +Glycosylation 28 55 3.675836663359712 0.0002370711737462 13.33495145631068 45.42718446601942 0.831363055351092 0.4028474919440285 5.5712021107485015 7.578523489860055 1.3433056638769032 0.3649215649501745 0.0004673517409154 0.1826627820387037 0.20003379484876 0.0165950302607688 3.2787722834546175e-05 +Glycerolipid biosynthetic process 30 50 3.657141681896889 0.0002550434221231 13.466019417475728 44.71844660194175 0.9430872689732808 0.3767257192898063 6.88753698417372 8.249645447783736 1.3199493331746477 0.3584243730449019 0.0001927018339806 0.5851156872439878 0.2475305235196633 0.0014438754065065 0.0004515292544847 +Carboxylic acid transport 25 37 3.654971707732203 0.0002572103411093 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.0001756711566343 1.0 0.078260139280739 0.0413515024466966 0.0015707250081793 +Localization within membrane 62 185 3.650266951009744 0.0002619679032971 43.83252427184466 179.48543689320388 0.7329824809593914 0.5973922945503244 12.803162929787796 21.32668417309247 1.133148805830878 0.4087008058998355 8.784079070842323e-05 0.2001597763973769 0.0059281210061016 3.788461675714066e-05 3.1158356024014213e-05 +Glycerolipid metabolic process 40 71 3.644344603357883 0.0002680740451324 16.934466019417474 64.79854368932038 -0.000323163470851 0.4552448147740581 9.046432352430308 10.372466251166422 1.3758971299503038 0.353332456533291 0.0001851269308899 0.3318756245741759 0.2065419644469071 0.0025475550559014 0.0001383902125092 +Glycerophospholipid biosynthetic process 26 45 3.614684277479964 0.0003007138605797 12.407766990291265 39.55339805825243 0.6228968293784067 0.4586227574071144 6.110530292090928 7.803693618041913 1.233194093755117 0.3515784330467275 0.0004066691327563 0.5401572754935314 0.1951687603989087 0.0004877568989612 0.0006936842069111 +Golgi vesicle transport 44 135 3.5772751562212437 0.0003471946444622 32.30825242718446 130.0995145631068 0.5186556770214802 0.6391424830765352 11.558195085956042 14.851278907933963 1.0581936514451007 0.3745819971007444 2.1092255230733442e-08 0.3617750709606537 0.0392041770647755 6.62724936576017e-05 1.2349194022129906e-08 +Carbohydrate derivative transport 14 17 3.555425488051558 0.000377367884669 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 9.927278651168317e-09 1.0 0.0707844675435839 0.0007742112182462 1.8583008987334915e-09 +Organic acid transport 33 51 3.542871696402415 0.0003957952158359 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.0002297944692263 1.0 0.3755825390431737 0.2359296448343685 0.0003096612473601 +Glycerophospholipid metabolic process 35 64 3.5334819059278635 0.0004101241617744 14.597087378640778 57.060679611650485 -0.0519222534779674 0.4286122989812534 8.002292830543196 9.368077769293231 1.3877870839733877 0.3500560744701435 0.000119796980191 0.6330463801523987 0.3122385752137425 0.0042128798349138 5.411121547802856e-05 +Membrane lipid biosynthetic process 18 27 3.4914359087997724 0.0004804317148285 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 4.015608437652913e-07 0.3274019772455256 0.544786927477571 2.5917903680851456e-05 2.782749065303765e-07 +Endoplasmic reticulum to golgi vesicle mediated transport 35 76 3.461210261831396 0.0005377526279275 17.32766990291262 65.39077669902913 0.808881464821498 0.4942452999677598 7.539018980743236 6.620812461410292 1.284359804176963 0.3933269611423161 1.9436614457529416e-09 0.1054077938723316 0.0047300594781523 2.033133062369488e-05 8.41857174638429e-10 +Lipid localization 30 82 3.4244845888840185 0.0006159667793852 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 3.771922463005177e-06 0.2873388595440179 0.0186875909530785 0.0027030048581013 8.224879826499155e-07 +Establishment of protein localization to membrane 39 96 3.37791506002382 0.0007303763720574 23.133495145631063 87.3616504854369 1.231448880072231 0.4195243824117992 8.397245527204214 9.510228790351464 1.3947369206386535 0.4065372973031916 1.073694926014335e-05 0.07440901727418 0.0007049187736698 8.534509218708185e-06 1.6697460267961832e-06 +Carbohydrate derivative biosynthetic process 53 174 3.271865219972646 0.0010684049583564 34.89320388349515 157.5752427184466 0.1333925495981435 0.673754283550047 12.337615244823663 15.61138085883912 0.9078866636106409 0.345023479104077 3.472875431991376e-07 0.3150553002675424 0.0411693177544375 0.0003725192997035 1.73399877641822e-07 +Inner mitochondrial membrane organization 16 22 3.234063939536058 0.0012204212969308 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 7.672440891884366e-06 0.0135379522122687 0.0051311282902344 2.159661966497117e-06 8.070770128897746e-09 +Phospholipid biosynthetic process 32 63 3.213535731170307 0.0013111148352695 15.191747572815531 54.88834951456311 0.3601791313916425 0.5325104042072244 6.85810624136386 9.315774292776531 1.1122724170508866 0.3517335331311575 0.0001574299104131 0.2390350583825033 0.1133743690327147 0.0008371766481312 0.000163563985552 +Protein transmembrane transport 14 25 3.2022551782840503 0.0013635615040605 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 2.670091608779895e-05 0.0020640692536444 0.0015776300418353 0.0087768454005906 9.364249306200338e-07 +Cellular ion homeostasis 37 94 3.1110183438628782 0.0018644335694328 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 0.0007821226269689 0.1430583240174933 0.1185081782259043 0.0666863988184008 5.252163963839571e-05 +Nadh dehydrogenase complex assembly 17 33 3.101600670618358 0.0019247741326775 9.266990291262136 26.96359223300971 1.1245271541492263 0.3013677937017552 4.122702675359976 4.029157649894909 1.4460543016521823 0.3224564676521605 1.2317859061389068e-06 0.0001542186655055 1.556462488990862e-05 8.877157893981833e-07 3.500208308230872e-07 +Proton transmembrane transport 20 45 3.097203242881687 0.0019535588437469 14.28640776699029 43.01699029126213 0.7821394801431882 0.3918912894345224 6.076814900000799 3.1076483585332 1.5710697941383835 0.3739424994204808 2.461714497726335e-06 1.0 0.0602097240350527 0.0004269964001107 8.49923967893284e-08 +Ion homeostasis 42 113 3.0856042186803543 0.0020313901973894 28.021844660194176 105.69174757281552 0.8349951537384392 0.4299135801564597 10.40966729997928 11.411952082971936 1.4722934854811005 0.3963893325418664 0.0043027257856166 0.0745157705462292 0.0963343614093384 0.1064118933630016 0.0001421399145457 +Liposaccharide metabolic process 10 20 3.083588698755046 0.0020452013289324 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 6.0243844797926816e-05 1.0 1.0 0.0127222619547071 8.547445272644024e-05 +Nucleotide transport 11 14 3.06593060568167 0.0021699367058143 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 1.8348956220832832e-08 1.0 0.0251008323038497 0.0032545859437725 7.265582894525532e-10 +Inorganic anion transport 13 28 3.008146960665781 0.0026284599773056 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 1.0135836046945845e-05 0.0432831882721129 4.690873944751423e-05 0.0013192316861744 4.123550941138705e-06 +Phospholipid metabolic process 40 84 2.997000352765663 0.0027265039782107 18.805825242718445 74.80339805825243 -0.0109191555178773 0.4658808189502442 8.677118948764809 11.032066592781655 1.2956045948013235 0.3559409313369701 0.0002915752069111 0.345996509904599 0.2225337724277162 0.0034049093129523 9.374094206249624e-05 +Nitrogen compound transport 191 572 2.9675557397477528 0.0030017785007101 134.15533980582524 569.4538834951456 0.9072063241864304 0.6401677607980054 37.1767641393764 58.81145048559368 1.470232145086419 0.4303798393104362 1.0138217440122055e-09 0.3504469154995983 0.0049659139961542 1.44136225028306e-05 1.6794219305391668e-10 +Sphingolipid biosynthetic process 12 18 2.9634496196426885 0.0030421185558526 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 7.010707878827587e-05 0.2480154974279715 0.4319828126458854 0.000511542389694 0.0001005734989968 +Intracellular protein transmembrane transport 16 22 2.934223801320421 0.0033438300725516 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.0014652058465418 0.0196403757049561 0.0088720794008613 0.0227330174276438 4.328991390290288e-05 +Chemical homeostasis 60 181 2.931367643378928 0.0033747313795318 43.762135922330096 177.7597087378641 0.7082111793088889 0.511106347874914 13.668464281922288 17.87763227716401 1.3204137511810292 0.4179418895476048 0.0003713021923276 0.049697097202694 0.1609036368237083 0.0286050281936584 6.172888877581866e-05 +Protein targeting 35 116 2.927848704276073 0.0034131608784429 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 1.1067952291198508e-05 0.0068519784881021 0.0006230635039213 3.595158196022232e-05 3.819688944372562e-06 +Protein insertion into membrane 16 32 2.9063230340789388 0.0036570369272725 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 2.670141572118497e-06 0.0248381956323572 0.0001167245250019 2.982863541569977e-07 5.792301542926626e-07 +Ph reduction 6 15 2.845357690364051 0.0044361576967462 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 0.0005548107931337 0.0078974776787256 0.0288389511657702 0.0291459656321865 0.000285052067186 +Carbohydrate derivative metabolic process 75 275 2.839399912998769 0.0045198471745317 52.560679611650485 256.59223300970876 -0.2905800319656845 0.6714103222597233 16.554227088257075 23.412587641314047 0.9410140760631216 0.3434766696433585 3.394719203661004e-07 0.1023054028056593 0.0257505406686443 0.0003814165705895 1.0179591904641897e-07 +Metal ion transport 36 106 2.832245453617784 0.0046222351881541 24.868932038834952 99.21116504854368 0.6600358663497399 0.5322554902435589 9.162889792248723 11.473971032908404 1.1670714049066973 0.3920241658733104 0.0453650615101622 0.5023005139274972 0.2364961234198578 0.1362001381441055 0.0176894355338313 +Amino acid transmembrane transport 11 16 2.827813476811873 0.0046867104744323 6.213592233009709 14.228155339805824 0.7890307267204019 0.3318923540291705 3.493823914060917 1.9561661273054285 1.3497309258640615 0.3227865040448734 0.0085887369670899 1.0 1.0 0.3140672800286707 0.0245462392153625 +Metal ion homeostasis 34 86 2.8183873549683898 0.0048265543331553 22.37864077669903 79.5 0.7762327689006491 0.4501210966631583 8.485414676383348 8.298876985671072 1.3957415688189287 0.3857448193070677 0.0241893139449361 0.1320457949075564 0.1054923769847168 0.1043200840699292 0.0009150911013548 +Cellular monovalent inorganic cation homeostasis 11 28 2.810090011989752 0.0049527646167508 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 0.000474993012268 0.0345877004093447 0.1143886596739273 0.0593060830293246 0.0001376865335326 +Endoplasmic reticulum tubular network organization 8 14 2.809690347099516 0.0049589185639951 4.150485436893204 10.555825242718448 0.8961707031484618 0.3171343629503343 2.1669796342432037 1.8339543060404635 1.2935176897309475 0.3199619326088047 2.963462146345372e-09 0.0029386578360865 0.0111011801010317 1.837861939916845e-06 2.269129992872316e-08 +Regulation of hormone levels 25 59 2.8024525714108326 0.0050715672888217 15.682038834951456 62.25485436893204 0.7754141622249116 0.4638741971732045 6.630568201753413 6.49574922456989 1.111399769110166 0.3798141702267368 0.0390175072199901 0.6523759430413363 0.3409917588407842 0.1544336478587294 0.0334144880155904 +Amyloid precursor protein metabolic process 8 19 2.792717415068462 0.0052267330053008 5.91747572815534 20.04368932038835 1.2306110398413417 0.2828388345239639 2.574706211328507 3.0661056512526157 1.0127867956133585 0.2841981221806073 0.0010732385029459 0.0022960708364777 0.0153233347656195 0.0432632841258681 0.001152884459637 +Sterol metabolic process 17 38 2.7879956056171795 0.0053035263199483 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 1.8572073317121787e-05 0.3371313972628795 0.1936799284616789 0.0166326939811153 2.4318243329258188e-06 +Oxidative phosphorylation 27 69 2.7795228063490875 0.0054438830708762 18.140776699029125 60.61893203883495 0.8137621380364766 0.3661293054253088 7.750013302753429 5.582386553809936 1.7413544544034578 0.3762713520958283 1.1088027162965417e-07 0.0024928514015356 0.0009274695924518 9.719570353971262e-07 2.074090891509611e-07 +Protein n linked glycosylation 15 26 2.7724410496346583 0.005563759578252 6.177184466019417 18.78640776699029 0.2004880128160887 0.4683260162783809 3.1676710128395498 3.0254598797887766 1.208633498192774 0.333447209788965 0.0002819688807108 0.0305319028295214 0.1021730546658088 0.0118522943314895 1.3514501341807656e-05 +Cytochrome complex assembly 10 13 2.770959966628742 0.0055891298038184 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 3.582007489308561e-06 0.151306852499084 0.0002868050489301 1.3471769237547282e-05 2.872856538426174e-06 +Protein localization to endoplasmic reticulum 16 36 2.767130875841017 0.0056552047145854 9.50242718446602 34.50485436893204 0.9935384348474128 0.428255638055916 4.399083524593319 2.6617527855555916 1.1934894982037212 0.3717243536861919 8.413843607421756e-06 0.0305319028295214 0.002067436699404 0.0024061053673092 2.282027754593884e-06 +Mitochondrial fusion 11 17 2.734159742607896 0.0062539695491483 5.730582524271845 14.140776699029129 0.9082040747396848 0.3521825448687026 2.97444400458197 2.016819417247653 1.0465735301082626 0.3054031781597867 0.0044374904949104 1.0 0.2423974925429197 0.0319451393300601 0.0003603172913213 +Hormone metabolic process 14 26 2.7293208310203205 0.0063464925758414 8.95631067961165 28.65776699029126 1.130508313948193 0.2963365150575847 3.9674689274001818 2.5345884681715156 1.346801337886388 0.3240077568826507 0.0320410680402781 0.3746890061856052 0.235580241074313 0.0296866330747937 0.0182973469936493 +Organelle fusion 22 50 2.698436569860854 0.0069666012712663 14.74514563106796 45.383495145631066 0.6448767361523368 0.5292766623385164 6.293825046556003 6.576179389035289 1.1045479661060835 0.3741954647136961 0.0132894260156024 1.0 0.3026517532146166 0.0220782152653952 0.0013517882500731 +Vacuolar acidification 5 11 2.663736662649765 0.0077278031793057 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 3.782863969644887e-05 0.0032958763634803 0.0124120710913681 0.0086586519898169 0.0001382662061028 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 9 27 2.660004336661456 0.0078139645385681 7.771844660194175 26.825242718446603 1.1714448828781496 0.3436005361805324 3.811248488859092 3.450558374586287 1.1733172803389544 0.345676809182098 5.987401027810717e-05 0.0213158974187442 7.85440343876941e-05 1.4280312346792963e-05 6.441778217365251e-05 +Nucleotide transmembrane transport 8 11 2.652150024588735 0.0079980995385979 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 9.633243511393946e-07 1.0 0.0098557770733155 0.0061570039439817 1.1152941299486122e-08 +Monovalent inorganic cation homeostasis 11 32 2.65053560790198 0.0080364255541669 9.014563106796116 27.87378640776699 1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 0.0017770090297464 0.0479057539651017 0.1529837701743424 0.0994768290011166 0.0006950646060203 +Membrane lipid catabolic process 5 12 2.644157073383053 0.0081894643045985 5.854368932038835 11.361650485436892 0.500872843713425 0.1363587272813367 1.9603237645724247 0.9867004907377388 2.113024793917032 0.2289617793743788 7.400221131341273e-05 0.0919337377678228 0.1741653971767485 5.415752101895563e-06 0.0002658063039979 +Protein processing 11 42 2.643473566438282 0.0082060172798268 12.08252427184466 45.980582524271846 0.9011703887478908 0.3916089016010577 4.43430858840224 4.931040148104543 1.176660792763282 0.3507158233798557 0.0069519897103734 0.143685486645328 0.0433617035599321 0.0064629825009123 0.0362096190954636 +Amyloid precursor protein catabolic process 5 14 2.6376757732301144 0.0083476351481324 4.62621359223301 16.47087378640777 1.203006467000838 0.2754962460876 2.1329801006381106 2.1803683249886516 0.947433834000198 0.2709877848980267 0.0062137664371764 0.001202833620517 0.0083373177591013 0.0211003003498726 0.0182027983739356 +Endoplasmic reticulum membrane organization 6 9 2.6336537194792133 0.0084471588934944 3.5679611650485437 8.12621359223301 0.656874598832497 0.271683145803182 1.813579499342004 1.2879547393790816 1.532817064292788 0.2945772195616556 4.116742403443895e-06 0.0607401038440192 0.0065261066260236 0.0001991597833083 7.777797134892854e-07 +Purine nucleotide transport 8 11 2.62704634275509 0.0086129603056839 4.970873786407767 10.817961165048544 0.961055494000064 0.2880106547862709 2.8308505383502496 1.988649275322177 1.3314072021441097 0.3042395363852717 5.714174158713829e-06 1.0 0.1741653971767485 0.0828772873031817 1.3761260971064308e-07 +Regulation of lipid metabolic process 20 54 2.6153963094452672 0.0089123977549083 12.599514563106796 52.890776699029125 0.2189053156740071 0.4007176079141414 5.562295027948738 7.005213895866115 1.3822804240908182 0.3523493088444139 0.0627488594988301 0.0636643545059936 0.1087077032686177 0.0418448508426329 0.0050134882466329 +Dicarboxylic acid transport 12 20 2.6045012738105537 0.0092008078943768 5.718446601941747 16.097087378640776 1.1205667041867788 0.2998586575349944 3.584398436287638 2.226340822602054 1.0973546365412417 0.2986830136605488 0.0049226694507479 1.0 0.0603249601752956 0.2691814013824262 0.0146615808963511 +Calcium ion import 7 12 2.6018924026503973 0.0092710934491078 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 0.0515741689374079 0.1635258499471353 0.0051311282902344 0.0116952906397438 0.0312372972504735 +Vitamin transport 6 8 2.581122526313251 0.0098479622603482 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 0.0002256493082677 1.0 0.2052107238795277 0.0024022577840735 9.85727163050706e-05 +Protein localization to mitochondrion 19 62 2.568025979397744 0.0102279490391745 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 1.226117006405848e-07 0.0149620345130709 0.0036187432390879 2.908238193584641e-07 1.7855881710229953e-07 +Ceramide metabolic process 11 22 2.560426490194528 0.0104543777800407 8.191747572815533 19.060679611650485 1.0632949889077032 0.1865092544415649 3.2982239784478966 2.5917545738626013 1.8901201919357584 0.2494992632187684 0.0002819688807108 0.2406936845278361 0.4209558173560673 0.0024061053673092 0.0003483002608922 +Amino acid transport 14 24 2.5578148141992942 0.0105332168279654 7.771844660194175 19.75 0.8410032854505353 0.3449280742441291 4.117377746800764 3.003739578643708 1.287399790463736 0.3206698223659758 0.0046352895150921 1.0 1.0 0.2320869702147383 0.0175104162218513 +Steroid biosynthetic process 19 42 2.5548614494201023 0.0106230072884772 11.728155339805824 44.80825242718446 0.9874364787035632 0.3935759881445143 5.016369659264937 4.35272817633461 1.2862817592315925 0.3680333006848349 0.0011533309882965 0.3746890061856052 0.235580241074313 0.008907043045769 5.775966252820857e-05 +Atp synthesis coupled electron transport 11 44 2.5518508657281656 0.0107152373527998 11.567961165048544 37.61407766990291 0.6403585631460136 0.4181082416574377 5.189865284224125 3.9859091462453993 1.417482213086961 0.3703097362636519 3.659923191593267e-05 0.0005171916005075 0.0008570218070741 2.4085613774929296e-06 1.8310300442707157e-05 +Glycolipid biosynthetic process 7 11 2.53998875958146 0.0110856031580932 3.3009708737864076 8.701456310679612 0.8778541677747596 0.2891249509557468 2.0940737065519093 2.1465026455410077 1.206628042966233 0.2848826766737565 0.0003623120908106 1.0 1.0 0.0552623668853733 0.0002537843560276 +Lytic vacuole organization 7 23 2.527935861635711 0.0114735310076943 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 0.0076440650992836 0.0335548880884004 0.1112999318055074 0.0145897333531984 0.0077971233365964 +Vacuole organization 13 50 2.515356129384971 0.0118912199354939 14.220873786407768 51.74514563106796 0.8524122478550634 0.3147425083910056 5.370022076358251 7.439112114793103 1.7567175511320523 0.3563110134355993 0.0157415910375415 0.1706177828799348 0.1831436146887539 0.0812926464798529 0.0175952980314143 +Regulation of autophagy 19 91 2.5134737490995063 0.0119548674677716 20.118932038834952 94.3495145631068 0.711099590941891 0.531831837860264 6.9602150135047 11.998348379757145 0.9791686068293384 0.3767967479294735 0.0039102043365846 0.1419430986244559 0.0449513232798454 0.0062106893642606 0.0122012344655274 +Oligosaccharide lipid intermediate biosynthetic process 8 10 2.5128177931864504 0.0119771176787364 2.2742718446601944 5.390776699029126 0.4920123476052065 0.3335995467983793 1.5024311055989734 1.8021595402153228 1.3008390374829126 0.2934249582958821 3.782863969644887e-05 0.083126337411673 0.1581956798045988 0.0007750266814789 1.1673054874396336e-05 +Protein targeting to mitochondrion 25 48 2.472352632308571 0.0134227041611525 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 2.7201371432783137e-05 0.0085976741283889 0.0513073025143829 0.000259969323856 1.7670882642271793e-05 +Regulation of amyloid precursor protein catabolic process 4 12 2.464203425514478 0.0137318151500807 3.8859223300970873 14.189320388349516 0.723751929535891 0.4024575578925681 1.8731873759514015 2.0164571748807374 0.9921534445034136 0.3036488689822377 0.0068516550010284 0.0004690772729531 0.003389670482849 0.0069928111010265 0.0175495980740681 +Regulation of cellular ph 9 23 2.457863865766125 0.0139766143830601 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 0.0004854168565433 0.0230489069918226 0.0789867722235121 0.1140816659952819 0.0004815310793091 +Regulation of ph 9 23 2.457863865766125 0.0139766143830601 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 0.0007329569981345 0.0257535715284909 0.0874698992517949 0.1300529274831162 0.0007583614663082 +Lipid storage 10 17 2.4571744599697323 0.0140034663370109 4.543689320388349 16.905339805825243 0.2970217553985043 0.3661937485285719 2.202279044729986 2.0116820549871304 1.1851757279860726 0.2726034839593525 0.017984491627634 0.2333020504203794 0.0153233347656195 0.0102355224712358 0.0159325769563511 +Amyloid beta metabolic process 4 12 2.4568846218399587 0.0140147689527074 3.6771844660194177 13.24514563106796 0.6724101183977472 0.416551332754989 1.8088680779022668 1.8049556184618043 1.0101286409291856 0.3102485572243311 0.019284003916796 0.0009779903118871 0.0068495888428019 0.0166437437365411 0.0459721092243015 +Respiratory electron transport chain 13 57 2.453953785006094 0.0141295139194417 15.4126213592233 50.33495145631068 0.497076868891423 0.4388579749555677 7.129498131980449 4.223655269147207 1.4894225458303931 0.3736358875877055 1.5582795477049548e-05 0.0011305823171669 0.0021696295294656 4.6621634009032395e-07 2.8577325443546795e-06 +Neutral lipid metabolic process 8 16 2.435484003512155 0.0148718821512172 3.7645631067961167 14.638349514563108 -0.2959545341177167 0.2756576316525815 2.469308018590983 2.835760748630011 1.4124950075268554 0.2284226385878861 0.0137214766048905 0.0410390344011431 0.1333602667321652 0.0780890051531907 0.0148430138161315 +Phospholipid transport 8 19 2.4329557169741327 0.0149761323627519 4.038834951456311 13.844660194174756 0.8595089147672731 0.22382450694892 1.931709490395295 2.5542930986961077 1.4491821424024287 0.2459407475876757 0.0030717880962832 1.0 1.0 0.3495520980441666 0.0006545278337592 +Cristae formation 7 9 2.429304194470927 0.0151278338102827 4.740291262135922 8.861650485436893 0.8982766043222677 0.3392698633906088 2.216011442046921 0.6593503673812457 1.2485531022675598 0.3418736408093433 0.0015547812541629 0.001984476440523 0.0075668597133861 0.0041470760753771 1.4910096807023017e-06 +Sterol biosynthetic process 12 24 2.425084443342636 0.0153048263487993 7.281553398058253 24.52912621359223 1.190088798384403 0.3136799329736269 3.292879861326439 2.61838648411319 1.1232845583768152 0.3105481837594456 5.987401027810717e-05 0.2030241760545403 0.0734859631006396 0.0052710570752827 1.0580026408817895e-05 +Vitamin transmembrane transport 5 6 2.423735521049029 0.0153617885771619 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 1.124753552049134e-05 1.0 0.1336663515258769 0.000366006536683 4.220517679529315e-05 +Phosphatidylinositol metabolic process 13 26 2.4222684628709827 0.0154239512181963 7.276699029126213 24.17233009708738 0.2193691847999141 0.5876630132545575 3.543233778407185 5.836935574489807 0.8971743115051186 0.3206850707882694 0.0649666937643554 1.0 1.0 0.1339560302608873 0.0437612176678883 +Import across plasma membrane 13 19 2.4151592429666997 0.0157283316406426 6.601941747572815 18.643203883495147 0.5666543433877399 0.4743790616320767 3.944616106748078 3.664494750162088 1.0498181035479843 0.3397186310535848 0.3313953582452406 1.0 1.0 0.8448074381544391 0.1598072806616731 +L amino acid transport 8 12 2.4143172294500426 0.0157647300284449 5.114077669902913 11.91504854368932 0.7755289387861473 0.3283794523692901 2.998235059113201 1.3256494094845783 1.3058948249973923 0.3189923022900864 0.0395595995112291 1.0 1.0 0.1975866021584996 0.0793301652164311 +Establishment of protein localization 158 516 2.3983907253715864 0.0164672890879606 118.26941747572816 516.7257281553398 0.6520395559374618 0.679532677582667 31.472560658738065 53.21298128179791 1.2523101724416292 0.4083128036600569 4.00210230627396e-07 0.1381306438433492 0.0126309948819729 4.622045884995768e-05 6.126435420544326e-08 +Atp transport 6 7 2.3963295684012573 0.0165601928732626 3.4805825242718447 6.233009708737864 0.5838786306840471 0.3211615036091749 1.83337760624298 0.8807971179633459 1.3636108978108328 0.3170401972517012 8.85715625338688e-06 1.0 0.0824659877424542 0.1973959389561772 1.9336789717809308e-08 +Regulation of mitochondrion organization 10 51 2.3939613743119184 0.0166675039414172 12.08980582524272 45.08252427184466 0.8217268052205459 0.4563186211764868 4.409741308614158 5.146210353910189 1.120993905462196 0.3778427085178187 0.0034104068555737 0.4158765777114258 0.0040690395287651 0.0014236280399173 0.0025993568134289 +Steroid metabolic process 24 64 2.3928707166080234 0.016717130437668 17.82766990291262 66.9247572815534 0.9974586731388552 0.3270410156332073 6.090491666967852 5.93996409793671 1.7133199907504504 0.3720334828404655 9.466602775957568e-05 0.5310682828592934 0.4388578646091141 0.0044922754835291 5.442706051902282e-06 +Negative regulation of amyloid precursor protein catabolic process 4 9 2.391119005602967 0.0167971073382053 2.645631067961165 8.78883495145631 0.7296788020743029 0.3749260712143212 1.4314957008524525 1.1001198531094605 1.057374600950545 0.3066940057573566 0.0003373424853699 6.765318543664244e-05 0.0005152543640852 0.0006143549700213 0.0009780614297071 +Purine containing compound transmembrane transport 6 9 2.385652045140106 0.0170488732825928 3.6432038834951457 8.228155339805825 0.8480777288434221 0.3004167480224937 2.0847056152178514 1.431742605530374 1.2278207398320582 0.2967021731271802 0.0001200304486802 1.0 0.1253337423142017 0.0435926191526008 1.4910096807023017e-06 +Autophagy of mitochondrion 10 36 2.3756569589476144 0.0175177402222566 8.643203883495145 32.55582524271845 0.5912176019297528 0.507260115546458 3.9310041488944902 4.499114265424183 1.01585008111736 0.3556742421157408 0.0023585294790467 1.0 0.1629989722901094 0.0023184274251433 0.00098208035012 +Amyloid beta formation 4 10 2.3651240237376063 0.0180240338387696 3.4466019417475726 11.150485436893204 0.7369482521385301 0.3719348072839057 1.602353580483856 1.6769930201386472 1.043709172018907 0.2948415726419107 0.0088955425406483 0.0005621116792476 0.0040337600577914 0.0086864012748381 0.0224202020359025 +Protein localization to extracellular region 26 61 2.3554008760033924 0.01850273279802 14.08980582524272 60.1626213592233 0.3740636626751541 0.6804633719835338 5.5124918123942495 7.043227203431352 0.6880222056686158 0.320722083725093 0.0262700437856963 1.0 0.5312624761966952 0.1631789723605528 0.0178488483748804 +Phosphatidylglycerol metabolic process 7 14 2.3273974396128234 0.0199441219137674 3.7572815533980584 10.78640776699029 0.7074456860764219 0.3298030384317407 2.521619218643941 1.658461595229837 1.2128783939533223 0.2875854965146425 0.0002874289599044 0.1135912525516411 0.0233124310373507 0.0215683584236732 0.0001312671913829 +Protein transmembrane import into intracellular organelle 10 13 2.315769357055683 0.0205708651856304 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0051610552303989 0.134742527043449 0.2496255286594674 0.1627514901813832 0.0134356018089951 +Process utilizing autophagic mechanism 34 161 2.2936175394501377 0.0218124770241412 37.22330097087379 158.8252427184466 0.4533218180510577 0.6759877406594806 11.85403297791327 20.589929287102564 0.8897283418769861 0.36588075882003 0.0015101993336577 0.354992113938649 0.0578877059529859 0.0048528897238904 0.0012930626149955 +Respiratory chain complex iv assembly 6 7 2.2929675589922205 0.0218498727217972 2.7475728155339807 6.451456310679611 1.036831430168084 0.2562354664331627 1.605321530277248 1.669274831081891 1.262804896468415 0.2848709091577191 0.0022505375657808 0.1135912525516411 0.0016492758756177 0.0028063338575205 0.0009886385516079 +Aminoglycan metabolic process 8 18 2.2911730322204757 0.0219534080331857 6.650485436893204 15.218446601941748 0.5538240398360251 0.1973407167351751 2.4739761552565955 2.4752855115427597 1.8355272359461776 0.2521795038965069 0.0877790889818719 1.0 0.4481347679758058 0.0622490701590107 0.1785456633921929 +Phosphatidylinositol biosynthetic process 8 23 2.290901558230003 0.0219691078501156 6.497572815533981 21.75485436893204 0.2324608584633621 0.5823932566767777 3.2482248971649077 5.447062157148579 0.8872279359639678 0.3154734680996093 0.0777835727598365 1.0 1.0 0.0851257395407892 0.0441133347827278 +Glycosphingolipid metabolic process 4 10 2.287248337342827 0.0221813320874781 4.764563106796117 9.184466019417476 0.4485135251287195 0.1553285492394019 1.7516723087054535 1.7320372023153958 1.93068386398988 0.2217231968869004 0.0078273399170881 1.0 1.0 0.1887844423268079 0.0198874102408346 +Organophosphate biosynthetic process 35 171 2.279328352045072 0.022647553872936 36.199029126213595 158.01699029126215 -0.237603877887742 0.6706800484803811 12.82421098574562 15.805467981876378 0.7823259717447805 0.3211878058592721 2.9159221059440243e-05 0.3057515911394269 0.0889270134413097 0.00029357259882 0.0001198525912226 +Phosphatidic acid metabolic process 4 8 2.2628108197767016 0.0236473536504919 2.2233009708737863 6.235436893203883 0.8816881639607732 0.2856229767394486 1.614148841412113 1.5439850574626743 1.1927985254107716 0.2824496640110863 0.0027002517582552 0.1178616319260966 0.2202973788945578 0.0239571113561098 0.0072634035650054 +Inorganic anion transmembrane transport 7 10 2.251209180038719 0.024372291743151 3.4101941747572817 8.983009708737864 1.1245392058053427 0.2357455210082705 2.3748669786284156 1.7214248641786654 1.1968417731555627 0.2697184972505711 0.0975997694502972 0.1305522111527444 0.0307863463383066 0.154226710893935 0.0116464914628391 +Cellular homeostasis 45 145 2.2480982585449616 0.0245699251073194 35.03155339805825 140.69660194174756 0.4666088113804902 0.5685618966047314 11.62423291193178 14.777892439656425 1.1736922314243927 0.3887657095146841 0.003283656258126 0.1445814994894414 0.2145829009055904 0.0874961094452885 0.0012394334512604 +Regulation of toll like receptor signaling pathway 3 9 2.2456710895115903 0.0247250832888077 2.587378640776699 9.50485436893204 0.9772136844316576 0.3297728067967737 1.666236944633112 1.8466647258935645 0.9012634534298872 0.2761306672489575 0.0755111914609591 0.1835089509173778 0.3312162786192844 0.2691814013824262 0.1428427753867574 +Regulation of lysosomal lumen ph 3 7 2.2314030819190016 0.0256544408995589 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.0020567301082413 0.0022827689145391 0.0086772133501052 0.0495157384890535 0.0047772438954047 +Lysosomal lumen acidification 3 6 2.2207370223292484 0.0263687783254946 1.9077669902912624 4.094660194174757 1.0430284513288333 0.1731957374320673 1.0102570393282595 1.1504623937719378 1.495459416196642 0.2154807950267566 0.0005615992373994 0.0012105019492812 0.0046590638338273 0.0276231155809849 0.001347246206883 +Transition metal ion homeostasis 10 25 2.2080837600885115 0.0272384348579044 6.640776699029126 24.57281553398058 0.9239194315613378 0.3015424973151205 2.934079531592402 2.8081087224394015 1.2471169312381896 0.2974369333820005 0.0330027651482204 0.0066118310835921 0.0070126150189725 0.1274569302589828 0.0145681033737178 +Regulation of membrane lipid distribution 3 8 2.2062667425253357 0.027365328544104 2.2475728155339807 5.5 0.9490281853542848 0.2470521989607894 1.5110816970578842 2.070950253254846 1.235309366119274 0.2447223644308076 0.0184273216152928 1.0 1.0 0.4832891613764908 0.038957699017471 +Tetrapyrrole metabolic process 8 20 2.2053448605446304 0.0274299041278649 5.652912621359223 19.283980582524272 1.0342508202848784 0.290677507336007 2.6828141040028877 2.549402305664568 1.2308389507353266 0.2976223887279709 0.0254774575922873 0.0188245552589776 0.0654836355539999 0.0211003003498726 0.0047344797567726 +Connective tissue development 12 26 2.20526959620321 0.0274351820111884 6.759708737864078 24.91747572815534 0.897701915164713 0.400129048313066 2.7453452066208146 3.8608044632925673 0.8993390896039578 0.3237981500894625 0.1172636236481749 0.462328834210194 0.3446196521996158 0.3728569773131227 0.0900394049996106 +Ceramide biosynthetic process 8 12 2.2043243216253523 0.0275015436671988 4.033980582524272 10.24757281553398 1.048715387316577 0.2344614502118888 2.237979905601341 2.0281678881596505 1.4071730245015133 0.2685344998940062 0.0019069619519214 0.1553991536419083 0.284754537798848 0.0096252938706505 0.0012078422816892 +Proteoglycan metabolic process 4 8 2.1937259880270465 0.0282551143678364 3.0558252427184467 7.347087378640777 0.90943742591388 0.2775323863615319 1.813993622553226 2.3052106999156825 1.19959130355936 0.2714444012698452 0.226183610577434 1.0 0.3376050929703735 0.0846608217542885 0.3440652150322754 +Lactation 5 10 2.1913160314608446 0.0284289307354836 3.2402912621359223 11.305825242718448 0.5550214141434973 0.4814819551144184 1.865118729821621 1.366614784589971 0.8532521714833784 0.3023533937292395 0.0059643195064532 1.0 0.2567853086841904 0.0379489226270714 0.0154010672791248 +Intracellular protein transport 100 325 2.1852900933955213 0.0288675832999365 72.23543689320388 320.84466019417476 0.4871189760263694 0.7214714639205947 20.45645165050656 29.914524602040487 1.0524664106682724 0.3751399671828122 1.4599434786889143e-05 0.1090024786788255 0.0052236373578226 0.0005154345833972 1.9811517018637066e-06 +Transition metal ion transport 8 14 2.1848702818317123 0.0288983590460194 4.70873786407767 14.08980582524272 0.8861898222657586 0.2678437025860737 2.4756329698054333 2.718007722894407 1.3738160036140448 0.271065502827487 0.0246339741117054 0.2480154974279715 0.1082339466870539 0.053649406266927 0.0227402044332229 +Regulation of release of cytochrome c from mitochondria 3 11 2.1845547368022458 0.0289215097614634 3.6310679611650487 10.805825242718448 0.7924389389582319 0.4006886058463786 1.815469081442188 1.3603843861930187 0.9712392086725492 0.3199873643457663 0.1136831966124214 0.1389130578490434 0.2567853086841904 0.0379489226270714 0.0601547876346515 +Regulation of protein exit from endoplasmic reticulum 4 8 2.184042129956753 0.0289591524234278 2.487864077669903 6.131067961165049 0.614536574202818 0.458469843561175 1.597129798474628 1.7824129563144424 0.9381550143256092 0.3206976005104832 0.0007687310007342 1.0 1.0 0.3867116248199588 0.0021733610219195 +Regulation of glycoprotein metabolic process 5 11 2.174579490818356 0.0296616426112148 3.592233009708738 10.70631067961165 0.6804974065630551 0.4353046559123504 2.03935499608955 1.985055569049905 0.9883671343018048 0.3255557758909779 0.0208670122612386 1.0 1.0 0.4957890007184933 0.0018597368387043 +Lipoprotein metabolic process 7 19 2.1710386205066 0.0299282531192053 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.1064373983608709 0.3371313972628795 0.5577603769600794 0.1492356701793886 0.0520924601126234 +Determination of adult lifespan 1 6 2.1693944083883 0.0300527531294854 1.4684466019417477 6.878640776699029 0.9172678211727472 0.3356532972350567 1.327993783820954 0.8617154358126836 0.9778379941999832 0.290947936133699 0.0981089285444625 0.0652597674910206 0.1253337423142017 0.0435926191526008 0.1443690348485063 +L alpha amino acid transmembrane transport 6 10 2.1689823564912767 0.0300840234324277 4.480582524271845 10.533980582524272 0.7590361902351016 0.3223730555033793 2.606398335255894 1.1951807271273862 1.273814103695318 0.3116596719827348 0.1306895040375719 1.0 1.0 0.5539124029112868 0.2117846302230147 +Cellular hormone metabolic process 8 15 2.157604314534342 0.0309586089692019 5.441747572815534 17.32766990291262 0.9908884218524354 0.2940959275691314 2.8170777488519256 1.7185203072340225 1.2515909253444888 0.3031653223897966 0.0444693307131987 1.0 1.0 0.0341229578056568 0.0981353394540022 +Activation of cysteine type endopeptidase activity involved in apoptotic process 4 14 2.150948437928553 0.0314802697121563 3.70873786407767 13.99514563106796 0.5808295381764595 0.4673885443392948 1.7355845547880226 1.639907565520626 0.8663105451530787 0.2938233201999538 0.0444693307131987 0.2183067054048652 0.012498849387857 0.0341229578056568 0.0981353394540022 +Cartilage development 7 16 2.147210516115908 0.0317765258840352 3.932038834951456 14.283980582524272 0.7074320636322524 0.4287139668901396 2.125947582774665 2.5119975572795252 0.8798730191625526 0.3016172221818579 0.2684985174099329 0.3561784256622231 0.2145288095929067 0.3769372615021911 0.4492598697594486 +Triglyceride metabolic process 7 12 2.1470060607252703 0.0317927991146718 3.4805825242718447 10.771844660194176 0.9779567044833 0.270555786798488 1.9834538010888536 2.3392770219831345 1.099054194056709 0.249087443977639 0.0027381773960575 0.0239365913088697 0.0817843887075946 0.03203241935523 0.0096315213740099 +Cellular transition metal ion homeostasis 8 20 2.1437973117238065 0.0320491308422028 5.893203883495145 20.42233009708738 0.9608801516152976 0.3243056832171095 2.800529150274697 2.6932649561537056 1.130076157725316 0.3011842711337114 0.0373936441621624 0.0388410242837302 0.023840460527523 0.2067196289529824 0.0363470309637756 +Regulation of protein secretion 16 39 2.1423468878533987 0.0321655784050018 9.725728155339803 40.37135922330097 0.4397575592309385 0.6317801864713505 4.052449601261029 5.3326667855507255 0.7141892385666174 0.3295535821820476 0.0480417119215311 1.0 0.6965590750616757 0.3508407564167967 0.0764602431514414 +Porphyrin containing compound metabolic process 7 17 2.132957866388826 0.0329281826944589 4.91747572815534 16.531553398058254 1.0269348271542438 0.279733852070357 2.276512713100022 2.089380108414912 1.2578863722796805 0.2914421038569487 0.0100603059721957 0.0121686135974036 0.043496878178469 0.0096252938706505 0.0060226058745804 +Positive regulation of i kappab kinase nf kappab signaling 7 38 2.1273049532766297 0.0333947534734133 7.344660194174757 35.86407766990291 0.4790737148931881 0.5397451864543208 3.344702467076835 5.27321228840899 0.8885741992578381 0.3336801499419705 0.1061028668532705 0.0220060448297376 0.0067115699799575 0.0315515858294127 0.2561369222297043 +Alcohol biosynthetic process 14 35 2.115775785454272 0.0343638814781166 9.344660194174756 36.09466019417476 1.0726679306851277 0.3539682718575088 3.792896481514287 3.1078151772256564 1.1587776417647702 0.3419459456532639 0.0018827387459198 0.3467229085425889 0.5703677906367757 0.0194272316030456 0.0002847267225419 +Copii coated vesicle budding 13 23 2.1146140846592494 0.0344628522377175 5.366504854368932 20.281553398058257 -0.0870141878263895 0.6284011720479112 3.001479314474639 1.4889070450824726 0.7985786878720158 0.3063787085486295 0.0234957357441317 1.0 1.0 0.5079876539292768 0.002250889764146 +Secretion 45 149 2.101931194553728 0.0355593034821504 33.99271844660194 147.42233009708738 0.4048828366720226 0.7039215372882776 10.476160889322964 16.385711464618055 0.7463810424968602 0.3447407367793494 0.0452991151133567 0.6518998969843408 0.2681577024106066 0.3102608565970305 0.0788928591106225 +Protein maturation 12 64 2.096446754875687 0.0360425785321152 16.635922330097088 69.29611650485437 0.7279397561088901 0.5092233260742579 5.6828366082703345 6.923625268615643 1.0037762420957868 0.3621314209884535 0.0448650848711097 0.2515369543584532 0.1246031715103092 0.054602117773195 0.1736165650583052 +Lipid translocation 3 7 2.092783167046216 0.0363685151216817 1.720873786407767 4.390776699029126 0.721199302569061 0.3015554657161993 1.2968412758505727 1.7626690867431634 1.2167340583298332 0.2614747358309583 0.0089213648122906 1.0 1.0 0.4160065505344545 0.0196049214971061 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 2 9 2.089708587948647 0.0366439850881397 2.1844660194174756 6.834951456310679 0.545977919789521 0.4419917395206664 1.3706179799286058 0.8713017532498863 0.9059019047189482 0.2943524525214059 0.0072857896564987 1.0 0.0998570540504815 0.001983278822638 0.0137836522957773 +Embryonic digit morphogenesis 3 8 2.089497124301974 0.0366629965433982 1.4684466019417477 6.54126213592233 0.5989020645284063 0.4429704011231127 1.569266266788618 1.559731853735315 0.934963282113679 0.3039103680308826 0.4938146810779473 1.0 1.0 0.2781824052676386 0.6213978547074502 +Regulation of anion transport 8 12 2.0861369155849427 0.0369662226162794 3.657766990291262 11.50242718446602 0.7713855446015195 0.3761489496061844 2.0089273726107977 1.6987985280405251 0.9512307489218268 0.2850669663772418 0.1306895040375719 1.0 1.0 1.0 0.2117846302230147 +Mitochondrial atp synthesis coupled proton transport 5 12 2.0808114544495253 0.0374511673049331 3.9927184466019416 10.769417475728156 0.5022502301293951 0.29867761594221 2.4440229028906213 0.8937412640542226 1.3849431163992842 0.2834040324316194 3.782863969644887e-05 1.0 0.1581956798045988 0.0086586519898169 0.0001382662061028 +Cotranslational protein targeting to membrane 5 13 2.0769455511023187 0.0378065849133832 3.0024271844660193 13.269417475728156 0.6346620653188224 0.4380127158001767 2.1905565042006923 1.12246981946818 0.9482238550798552 0.3119643857898596 0.0390540123369527 0.0919337377678228 0.015225007352257 0.0828772873031817 0.0021733610219195 +Organic cation transport 5 7 2.072507661432628 0.038218122500029 2.191747572815534 5.524271844660194 1.626219676916526 0.1372808582950073 1.481153399412497 1.209546654977186 0.871004228766265 0.1892257790071234 0.0009776198561721 1.0 0.1820374447866984 0.0014320459890063 0.0027409433744388 +Aerobic respiration 21 97 2.0703722228676646 0.0384175009698897 23.075242718446603 86.43446601941747 0.4685851027775424 0.4381258038241513 10.546552774557412 6.275478278783705 1.570513830163352 0.3792860784147517 1.5381203204042574e-07 0.0069963732250582 0.0007797311297257 1.3676184949449754e-06 5.837017180922613e-07 +Response to mitochondrial depolarisation 2 10 2.062741960114516 0.0391371510081322 2.4635922330097086 7.439320388349515 0.5975404704267634 0.4417505348750569 1.531588016779825 1.096644274293901 0.8946129564546079 0.2998729921389195 0.0214626028283106 1.0 0.1419203898220533 0.0061570039439817 0.0391317335840731 +Er nucleus signaling pathway 7 15 2.057842518550186 0.0396052530677173 4.563106796116505 13.361650485436892 0.3617919622488442 0.4304556920046536 2.3428051517114805 1.3174649068389608 1.1974910326877934 0.3346175168774911 0.1577174272205327 1.0 0.2915824887707032 0.2153304097941032 0.0014381321258029 +Ceramide catabolic process 2 7 2.054875741207636 0.0398910081158379 3.8592233009708736 6.531553398058253 0.1286784152295923 0.1423502941444668 1.429436503356119 0.7012295128365029 2.0219843992394857 0.2259194528389771 0.009442019986145 1.0 1.0 0.0025975272437437 0.0177300896528831 +Mitochondrial cytochrome c oxidase assembly 5 6 2.049406545203796 0.0404223777643655 2.344660194174758 5.764563106796117 0.9954600272926416 0.2681565835601643 1.449018962088891 1.4364892997002987 1.2150903662861117 0.2820677765861404 0.0089213648122906 0.1006582454154426 0.0011273462404087 0.0152248647419399 0.003408516691131 +Atp synthesis coupled proton transport 5 13 2.042615504744168 0.0410905150404907 4.067961165048544 11.769417475728156 0.4798560195228825 0.3249136059986872 2.5150503707528173 0.8937412640542226 1.340203957668315 0.2941072770431484 7.400221131341273e-05 1.0 0.1741653971767485 0.0116756742779249 0.0002658063039979 +Amide transport 15 40 2.041697940769656 0.0411815031672571 9.512135922330096 37.99757281553398 0.8625203235532012 0.4243895840783888 3.9342099663331425 4.541875701235624 0.963016155404646 0.3369249994514658 0.0158700805813034 1.0 0.141777722869203 0.2359296448343685 0.03289719950909 +C4 dicarboxylate transport 5 9 2.0320388328840315 0.0421497248257041 3.441747572815534 7.932038834951456 0.5521079717004741 0.3962643111056436 2.364585978327258 1.2048618010613894 1.0992451565958017 0.3113965023368303 0.5047122063555045 1.0 0.1581956798045988 0.3559534457378639 0.589751978191033 +Electron transport chain 28 76 2.0302877209739663 0.0423273016201759 19.550970873786408 67.77184466019418 0.3712062453977176 0.4872800905659868 8.486701420407794 5.37626783377928 1.3790913022045077 0.3735693075609537 4.187095332245032e-05 0.0036241696225553 0.0084047560376835 3.405863057254344e-06 1.2383667438952385e-06 +Proton transporting two sector atpase complex assembly 5 6 2.023160050999202 0.0430566489305372 1.7432098765432098 4.6839506172839505 1.079697689782964 0.2705190312822739 1.1688274457451555 1.1775111637565157 1.0292886485906785 0.2668917829180481 0.0147610945171356 0.0652597674910206 0.0075668597133861 0.0435926191526008 0.0003569480206607 +Cdp diacylglycerol metabolic process 3 9 2.0101093772564105 0.0444196138114312 2.4393203883495147 6.388349514563107 0.0386959777105354 0.4087752339915881 1.6066329515606936 1.579498566792564 1.18423584316981 0.2981361461643844 0.0020567301082413 0.0697581245313758 0.0086772133501052 0.0495157384890535 0.0047772438954047 +Regulation of cysteine type endopeptidase activity 11 45 2.009102595058729 0.0445262545121689 11.024271844660197 48.30339805825243 0.4412193551169824 0.5489802671194735 4.186129802361243 4.9529522535570285 0.919025397001871 0.3400648922313719 0.0456792131152388 0.4978494903048275 0.1529318558315133 0.2585472367214217 0.148126087316442 +Early endosome to golgi transport 4 7 2.005350888739116 0.0449255480623367 2.320388349514563 6.650485436893204 1.001706299736163 0.3202433583076141 1.526233973035193 1.1381191933763375 0.8656979853859356 0.2689019049302471 0.0008170986671625 1.0 1.0 0.2541534411772372 0.0019443402252438 +Endoplasmic reticulum calcium ion homeostasis 4 8 2.0032707338671645 0.045148237001219 3.412621359223301 8.468446601941748 0.7163576234395546 0.3718536853795897 2.0059706805420334 1.5568434939403433 1.1166052913833018 0.3156746531372333 0.0089213648122906 1.0 0.1898352204968973 0.0152248647419399 0.003408516691131 +Intracellular transport 124 550 1.99680643936185 0.0458462137960837 120.90291262135922 544.3956310679612 0.5500812282996078 0.6924011803517542 31.43517433849213 53.582766758854405 1.193070641867047 0.396756529943003 3.020032192204728e-08 0.0726272803775181 0.0005528436900885 2.7617563403187148e-05 2.712472857835949e-09 +Sphingoid metabolic process 3 5 1.995039957166488 0.0460385220774146 2.337378640776699 5.174757281553398 0.8258730035764346 0.2192038420096116 1.196784089801513 0.5941001920342514 1.4738240163378542 0.2563928956394505 0.0054519195422099 1.0 1.0 0.0014684283121974 0.0008911424388636 +Signal peptide processing 3 6 1.993447191238112 0.0462125007302633 2.0898058252427183 5.155339805825243 0.788498872885968 0.2357910477072221 1.2938213743418876 0.7208043181852656 1.3841109341751536 0.2490116896927748 0.0005615992373994 0.0516364610584135 0.0998570540504815 0.001983278822638 0.001347246206883 +Body fluid secretion 5 12 1.991962907346568 0.0463751278417203 3.611650485436894 13.691747572815531 0.5614164790218804 0.4834047231691153 2.085469888187935 1.6735027663843434 0.894552067234308 0.3061879015966331 0.0277941005129711 1.0 0.3502020618548794 0.0940672040532474 0.0642230888772536 +Protein catabolic process in the vacuole 2 7 1.9910728191709517 0.0464728821797768 2.70873786407767 6.618932038834951 0.8383076008345888 0.2101105309103242 1.6017652153393662 1.88837291272598 1.5176899437744062 0.242508547144668 0.0390540123369527 0.0919337377678228 0.1741653971767485 0.0116756742779249 0.069181328144546 +Lysosomal protein catabolic process 2 7 1.9910728191709517 0.0464728821797768 2.6941747572815533 6.587378640776699 0.838918419522322 0.2080383809566978 1.5899151374262637 1.8707342212441815 1.5239608036504366 0.2420459791980847 0.0295641424094207 0.083126337411673 0.1581956798045988 0.0086586519898169 0.0531269764991638 +Negative regulation of neuron projection development 6 23 1.9860583897605943 0.047026840848251 4.944174757281553 19.932038834951456 0.8070712719008988 0.4165241941447024 2.3357271686464363 2.7475042016888107 0.8484003015222881 0.3001902418041021 0.0349880014892525 0.0576595399457578 0.1799401404284943 0.5857485166130989 0.0953620186642032 +Mitochondrial calcium ion transmembrane transport 4 9 1.9838578996815488 0.0472716833613364 3.4684466019417477 9.04126213592233 0.7792467211325117 0.2463779000555085 2.196969341156949 1.2010296388602075 1.3738174116662032 0.263849842646199 0.1231545342713074 1.0 0.1419203898220533 0.0557098434243155 0.0061301079468053 +Positive regulation of cysteine type endopeptidase activity 6 28 1.983020505922693 0.0473651390679534 7.196601941747573 28.478155339805824 0.6118231968344265 0.4994143481361404 2.711480107898675 3.3256882629722657 0.9483693928307184 0.340405399390541 0.0537350367748605 0.3498897642406863 0.0527430730742316 0.0637395822669413 0.1375829939443413 +Protein import into mitochondrial matrix 7 9 1.9698132046306365 0.0488597826645997 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0020567301082413 0.0697581245313758 0.1336663515258769 0.0495157384890535 0.0047772438954047 +Chloride transport 6 13 1.9652913737953 0.0493805234218311 4.33252427184466 12.12621359223301 1.0302584084066435 0.2341882174183942 2.3624510960969567 2.26059366569241 1.2797232968088257 0.2563105728143979 0.0078273399170881 0.1471951297158956 0.0390718495583504 0.0444854600227105 0.0008341806854412 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..52fb88b78c7c415cdd852229e10fc1edc57a7ab5 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 6472, + "title": "Average number of proteins per term", + "value": 19.112021013597033 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c98904b9217607cdb131d451d5d985bd6fd9316d --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..baeb758aa8739b6b9f091babaf649b19df048a6a --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1644 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transmembrane transport 0.5843865212616862 6.022495268932751 1.717483920159982e-09 1.1115494169729684e-05 1.1115555937747404e-05 222 Q99595,Q8TBP6,Q9BVC6,P45880,O75298,Q8WWI5,Q8N4V1,Q9UHG3,O75844,Q3ZCQ8,Q9NS69,Q9Y277,P17302,P21796,Q86VD7,P20674,Q9H2D1,P20020,Q9Y4W6,Q9H936,Q9UBX3,Q15629,P23634,O75964,P13073,O75027,O75323,Q9H9B4,Q8TAD4,Q9C0H2,Q9H2V7,P16615,O95563,Q9HD26,Q96HE7,P00846,O14925,P04062,P36542,Q00535,Q9BZF1,Q13586,Q7KZN9,P27105,Q9HC21,Q13546,P39210,Q9HD23,P00403,Q9HD20,Q02978,Q96ES6,Q6P4A7,Q8TDW0,Q70HW3,P30825,O00483,P28288,P38435,P03915,Q96PU5,Q9BXP2,O95831,P52789,Q96QD8,O75915,Q9UJS0,Q8TB61,Q14728,Q8WWC4,Q96DA6,Q15388,Q9UDW1,L0R6Q1,Q8WTV0,O75746,P33121,Q07820,Q00325,P14672,P53007,Q13423,Q4KMQ2,Q15041,Q7L0J3,P41440,P08183,Q96RD7,P12235,P24539,P98194,P49755,Q9BQT8,Q9H2J7,Q9BSK2,P56385,Q03519,Q15043,P23786,Q6NUK1,Q9UMX0,O43808,O75381,O96008,Q9H0U3,P56134,Q9Y6M7,O43615,O60831,Q96NB2,P12236,Q9BPX6,O95202,Q8IXU6,P51790,Q9UM00,O14678,Q99442,P51798,P61619,Q99623,P31751,Q9UGP8,P78417,P05141,P05023,P50416 127 +Ion transmembrane transport 0.5498621501702532 5.16696125042142 2.379305665927858e-07 0.0015387017928362 0.0007387987529676 164 Q9BVC6,P45880,Q8N4V1,Q9UHG3,O75844,Q9Y277,P17302,P21796,Q86VD7,P20674,Q9H2D1,P20020,Q9Y4W6,Q9H936,Q9UBX3,P23634,O75964,P13073,O75027,O75323,Q9H9B4,Q8TAD4,Q9C0H2,O95563,P16615,Q9HD26,Q96HE7,P00846,P36542,Q00535,Q13586,Q7KZN9,P27105,Q9HC21,Q13546,Q9HD23,P00403,Q9HD20,Q02978,Q96ES6,Q6P4A7,Q70HW3,P30825,P03915,Q96PU5,Q8TB61,Q8WWC4,Q9UDW1,Q13423,Q4KMQ2,Q15041,P41440,P08183,Q96RD7,P12235,P24539,P98194,Q9BQT8,Q9H2J7,P56385,Q15043,Q9UMX0,O43808,Q9H0U3,P56134,Q9Y6M7,O60831,Q96NB2,P12236,Q9BPX6,O95202,P51790,Q9UM00,P51798,P61619,Q99623,P78417,P05141,P05023 79 +Mitochondrion organization 0.5235122393794172 5.098442651891935 3.424592489024434e-07 0.0022139422450244 0.0007387987529676 206 Q9Y2R0,O75431,Q99595,Q9BUK6,O96000,Q96A26,P45880,O95139,Q99536,Q8N4H5,O43676,P03886,Q86Y39,Q9BUR5,Q5XKP0,Q9UDX5,Q3ZCQ8,Q9NS69,Q8N8Q8,P21796,Q9Y276,Q9H4A6,Q9Y4W6,Q9H061,Q5TC12,Q16706,Q969V5,O75323,Q9UG56,Q15070,Q13505,P49841,Q9Y5J6,Q69YU5,O14925,P04062,Q10713,O95169,Q8NFG4,P51970,Q9Y6C9,Q00535,O95298,P55786,Q9Y6M9,Q9BWH2,P39210,Q9Y371,Q9Y241,Q9P0J0,P62072,Q9H3K2,Q9H300,Q9NVH1,O75153,P03915,P52789,Q6DKK2,P27544,Q8WWC4,Q6UXV4,P51572,P12235,O14966,Q8N2A8,Q9BSK2,Q9NVI7,Q7Z3C6,O96008,O43615,P51530,Q9NX14,Q8IWA4,P49257,O75880,Q96CU9,Q5T9A4,Q9BUB7,Q9Y512,O95202,Q16891,O60313,Q8TB36,Q9Y375,Q99623,Q8NAN2,P05141,O75306,O43819,Q53H12 90 +Membrane organization 0.5078723578396526 5.005211130996181 5.580083562818887e-07 0.0036049177154366 0.0007738913405563 247 O75431,Q9NQC3,P45880,Q9UNK0,Q13190,P46379,P50897,Q9BUR5,Q5XKP0,O43760,Q8N4V1,O75844,Q3ZCQ8,Q9NS69,Q8N8Q8,Q9Y276,Q9H4A6,Q9Y4W6,Q15629,O14653,Q969V5,Q9P2W9,Q9NZJ7,Q15070,Q13505,Q9UH99,P49841,P16615,Q9Y5J6,Q8NC56,Q5JRA6,Q13636,Q9BZF1,Q9Y3B1,Q8NHH9,Q9NPA0,Q6NUK4,O60499,Q9BRK0,Q96AA3,Q9H6H4,Q9Y371,Q96A33,Q9P0J0,P62072,Q9H3K2,Q9NVH1,O15258,P52789,O94901,O14657,Q9NR31,O95249,Q8WWC4,Q12981,P50402,Q15392,Q9BVK6,O15228,Q4KMQ2,Q15041,P41440,Q00765,Q9BSR8,P08183,Q6UXV4,P12235,O15118,O75340,P98194,P49755,P62820,Q86XL3,O43681,Q8IXJ6,Q7Z3C6,P57088,Q16739,Q8IWA4,Q00169,Q9Y512,O95202,Q16891,P48739,P51790,O60313,P61619,Q15363,O15400,Q9H1P3,P31751,Q12770,P05141,Q53H12,P49354,O15498 96 +Ion transport 0.5141494834557438 4.991901808318518 5.978764991927439e-07 0.0038619811541553 0.0007738913405563 218 P14174,Q9BVC6,Q9UHQ9,P45880,Q8WWI5,Q8N4V1,Q9UHG3,O75844,Q9Y277,P17302,P21796,Q86VD7,P20674,Q9H2D1,P20020,Q9Y4W6,Q9H936,Q9UBX3,P23634,O75964,P13073,O75027,O75323,Q9NZJ7,Q9H9B4,Q8TAD4,Q9C0H2,O95563,P16615,Q9HD26,P00846,O15173,P07602,P36542,Q7KZN9,Q9HC21,P00403,Q9HD20,Q96ES6,Q6P4A7,Q70HW3,P30825,Q96S66,P03915,Q96PU5,Q96QD8,Q96BY9,P55061,Q8TB61,Q8WWC4,Q9UDW1,Q08722,Q13423,Q4KMQ2,Q15041,Q7L0J3,P41440,P08183,Q96RD7,P12235,P24539,P98194,Q9BQT8,Q9H2J7,P56385,O43681,Q15043,Q6NUK1,Q9UMX0,O43808,O96008,Q9H0U3,P56134,Q9Y6M7,O60831,Q96NB2,P12236,Q9BPX6,O95202,P51790,Q9UM00,P51798,P61619,Q658P3,Q99623,P78417,P05141,P05023 88 +Anion transmembrane transport 0.7405059856450078 4.736194686509645 2.17768402510643e-06 0.0139951310974225 0.0023489951684158 47 O60831,Q96NB2,Q00325,P12236,P53007,P45880,Q9HC21,Q4KMQ2,Q15041,Q13546,P41440,P08183,P51790,Q9UHG3,Q02978,P12235,Q9Y277,Q8TDW0,P17302,P21796,Q86VD7,Q9H2D1,P30825,Q9H936,Q9BQT8,Q9UBX3,P51798,Q9BXP2,Q9H9B4,O95563,Q9HD26,O75915,O43808,Q9UJS0,Q8TB61,P05141,Q14728,Q9Y6M7,O75746 39 +Anion transport 0.6424075140676447 4.533566242172775 5.799606651368805e-06 0.0368394505779899 0.0046918817809581 76 O60831,P14174,Q96NB2,Q00325,P12236,Q9UHQ9,P53007,P45880,Q9HC21,Q08722,Q4KMQ2,Q15041,Q13546,Q7L0J3,P41440,P08183,P51790,Q9UHG3,Q02978,P12235,Q9Y277,Q8TDW0,P17302,P21796,Q86VD7,Q9H2D1,P30825,P28288,Q9UBX3,Q9BQT8,Q9H936,Q9H2J7,P51798,Q96S66,O43681,Q15043,Q9BXP2,Q9NZJ7,Q6NUK1,Q9H9B4,Q9C0H2,O95563,Q9HD26,Q96QD8,O75915,O43808,Q9UJS0,Q8TB61,P05141,Q14728,Q9Y6M7,P07602,O75746 53 +Lipid biosynthetic process 0.5124560498761068 4.37026963849168 1.2409320660156098e-05 0.0771731174752925 0.0080313123312536 147 P14324,P14174,O00767,Q9NTJ5,Q9HCL2,O43292,Q15392,Q9UHQ9,Q8WUK0,Q11206,Q8NF37,Q9H7Z7,Q8NCG7,Q9Y6K0,O15228,Q96N66,Q14739,Q06136,Q5H8A4,O95470,Q8WWI5,Q15800,Q9NXE4,P35610,O14735,Q86YN1,Q96G23,Q16850,Q9P035,O15269,Q8NBX0,Q53GQ0,Q9UHI6,Q9BVG9,Q9NZ01,O95674,Q9H490,O75845,Q96JX3,Q14534,Q9UG56,Q9NPH0,Q6Y1H2,Q92643,P37268,Q92604,Q9H1P3,P11802,Q12770,Q9UBM7,P04062,Q10713,Q16739,P05023,P27544,Q86UL3,Q16880,Q9NX62,Q13510,Q8NBQ5,Q53H12,P04035,P16435,Q8WTV0 64 +Lipid metabolic process 0.4498670652929993 4.273264435570544 1.926317783906839e-05 0.1172140215536898 0.010389273914538 289 P14324,P14174,Q9HCL2,Q9HBH5,Q9UHQ9,Q8WUK0,Q8NCG7,O75352,Q9H6V9,P50897,Q8WWI5,Q15800,O75844,Q86YN1,Q96G23,P51648,Q9NZ01,O95674,Q14534,Q9UG56,Q9NZJ7,O14773,P04062,Q10713,P21964,P07602,Q9NX62,Q13510,Q9H6K4,Q9H3H5,O00767,Q11206,Q8NF37,Q9Y6K0,Q96N66,Q14739,Q06136,Q5H8A4,O95470,Q96AA3,Q8NBN7,P49356,Q9P035,Q53GQ0,P17900,Q9BVG9,Q9H490,O75845,P38435,Q9BT22,Q9NPH0,Q8N4Q0,P37268,Q99735,Q9UBV2,P27544,P04035,Q9NWW5,Q8WTV0,P09960,O43292,Q15392,Q9BV10,Q15067,Q9H7Z7,O15228,P40939,O14735,Q16850,O15118,O75340,Q8NBX0,Q5T8D3,Q16836,Q8N2A8,Q96JX3,O15254,O43681,Q6Y1H2,Q709F0,P23786,Q8IXJ6,P07099,Q92604,Q9Y394,O43808,Q16739,Q86UL3,Q16880,P16435,Q00169,Q9NTJ5,Q8N2K0,Q6PIU2,P48739,P35610,O15269,O14678,Q99623,Q92643,Q2TAA5,Q9H1P3,P11802,P31751,Q12770,Q9UBM7,P15291,P05023,A1L0T0,Q8NBQ5,Q53H12,P50416 112 +Membrane lipid metabolic process 0.695577219990315 4.252900760333644 2.110191076520884e-05 0.1276573695790432 0.0105055051132644 44 O43292,Q11206,Q06136,Q5H8A4,O95470,P50897,O15269,Q96G23,Q9P035,Q8NBX0,P17900,Q9NZ01,Q9H490,Q6Y1H2,Q92643,Q9NZJ7,Q99735,P04062,Q16739,P27544,P07602,Q16880,Q13510,Q53H12,Q9NWW5 25 +Organic anion transport 0.6618270395279144 4.206723119584019 2.591002654295238e-05 0.154385641437543 0.011977835127571 52 O60831,P14174,Q96NB2,P12236,Q9UHQ9,P53007,Q9HC21,Q08722,Q15041,Q7L0J3,P41440,Q02978,P12235,Q8TDW0,P17302,Q86VD7,Q9H2D1,P30825,P28288,Q9BQT8,Q9H936,Q9UBX3,Q9H2J7,Q9NZJ7,Q6NUK1,Q9H9B4,O95563,Q96QD8,O75915,O43808,Q9UJS0,Q8TB61,P05141,Q14728,Q9Y6M7,P07602,O75746 37 +Cellular lipid metabolic process 0.4571140174023733 4.11709388230322 3.836798079115411e-05 0.219891553917866 0.0165545047786903 224 P14324,P14174,Q9HCL2,Q9HBH5,Q8WUK0,Q8NCG7,O75352,P50897,Q8WWI5,Q15800,O75844,Q86YN1,Q96G23,P51648,Q9NZ01,O95674,Q9UG56,Q9NZJ7,P04062,Q10713,P07602,Q9NX62,Q13510,Q9H3H5,O00767,Q11206,Q8NF37,Q9Y6K0,Q96N66,Q06136,Q5H8A4,O95470,Q96AA3,Q8NBN7,Q9P035,Q53GQ0,P17900,Q9BVG9,Q9H490,Q9BT22,Q9NPH0,Q8N4Q0,P37268,Q99735,Q9UBV2,P27544,P04035,Q9NWW5,Q8WTV0,O43292,Q9BV10,Q15067,Q9H7Z7,O15228,P40939,O14735,O75340,Q8NBX0,Q5T8D3,Q16836,Q96JX3,O15254,Q6Y1H2,Q709F0,P23786,Q8IXJ6,P07099,Q92604,Q9Y394,O43808,Q16739,Q86UL3,Q16880,P16435,Q9NTJ5,Q8N2K0,Q6PIU2,P35610,O15269,O14678,Q99623,Q92643,Q2TAA5,P31751,Q12770,A1L0T0,Q53H12,P50416 88 +Cation transport 0.4765982426715554 4.071195888383057 4.677239577888237e-05 0.2611926077538568 0.0189194340925583 160 Q13586,Q96NB2,Q7KZN9,Q9BPX6,O95202,Q9HC21,Q13423,Q4KMQ2,Q8WWI5,Q8N4V1,P00403,P51790,Q9HD20,O75844,Q96ES6,Q96RD7,P12235,P24539,P21796,Q9UM00,Q86VD7,Q70HW3,P20674,P20020,P98194,Q9Y4W6,P30825,Q9H936,P23634,Q9H2J7,O75964,P61619,Q658P3,P56385,Q99623,P13073,O75027,O75323,P03915,Q96PU5,Q15043,Q9H9B4,Q8TAD4,Q9UMX0,P16615,Q96QD8,Q96HE7,O43808,P00846,Q96BY9,Q9H0U3,P78417,O15173,P55061,P56134,P05141,Q9Y6M7,P05023,P36542,Q8WWC4,Q9UDW1,Q00535 62 +Organophosphate ester transport 0.7232863016136823 3.976984094736497 6.97948313925778e-05 0.3634726630798682 0.0237743236196194 33 Q9Y3B1,Q00169,P12236,Q08722,Q9HC21,Q4KMQ2,P41440,P48739,P08183,P12235,Q14108,Q86VD7,Q9H2D1,Q9BSK2,Q6NUK1,Q9H1P3,Q7Z3C6,O43808,Q8TB61,Q8WTV0 20 +Mitochondrial transmembrane transport 0.6275792144044939 3.9408726765173094 8.118571251825024e-05 0.4087138866837602 0.0245211233004224 54 Q96NB2,Q99595,Q00325,P12236,Q9BPX6,P53007,O95202,Q9HD23,P12235,Q3ZCQ8,Q6P4A7,P24539,P21796,Q9H2D1,Q9Y4W6,Q9H936,Q9BQT8,O75964,Q9BSK2,P56385,O75027,P23786,O95831,Q9H9B4,O95563,P00846,O96008,O14925,Q9UJS0,P56134,P05141,O43615,Q96DA6,Q8WWC4,P36542,Q15388,P50416,O75746 38 +Glycoprotein metabolic process 0.5904663062288422 3.930665045948961 8.471121898900869e-05 0.4220536485129501 0.0245211233004224 72 O43505,Q9H3H5,Q93063,Q9BXS4,Q8N4A0,Q10469,Q9BV10,O60858,Q11206,P04843,O75352,Q7LGA3,Q96AA3,Q9NQX7,P35610,O60502,P46977,Q86YN1,O15118,O75340,Q9H4A6,Q8TCJ2,Q9H0U4,Q9H5K3,Q86SQ9,Q9BT22,Q8NCH0,Q8WVQ1,Q9UKV5,P62820,Q16706,Q2TAA5,Q9H0U3,P15291,Q9NX62,Q9Y287,Q10472 37 +Cation transmembrane transport 0.497412515134042 3.923708360627992 8.719628300957183e-05 0.4312753885925059 0.0245211233004224 124 Q13586,Q96NB2,Q7KZN9,Q9BPX6,O95202,Q9HC21,Q13423,Q4KMQ2,Q8N4V1,P00403,P51790,Q9HD20,Q96RD7,Q96ES6,P12235,P24539,P21796,Q9UM00,Q70HW3,P20674,P20020,P98194,Q9Y4W6,P30825,Q9H936,P23634,Q9H2J7,O75964,P61619,P56385,Q99623,P13073,O75027,O75323,P03915,Q96PU5,Q15043,Q9H9B4,Q8TAD4,Q9UMX0,P16615,Q96HE7,P00846,P78417,Q9H0U3,P56134,P05141,P05023,Q9Y6M7,P36542,Q8WWC4,Q9UDW1,Q00535 53 +Endoplasmic reticulum organization 0.6233848380502511 3.9041833667701704 9.454408065923126e-05 0.4576903968502478 0.0245211233004224 54 Q9NQC3,Q8NHH9,O95197,Q9NPA0,Q6NUK4,Q9BRK0,Q15041,P46379,Q00765,Q9NXE4,Q8N4V1,Q9H6H4,Q96A33,Q96HR9,Q15629,P61619,O43681,Q15363,Q9P2W9,P61026,O14657,P57088,Q12981,P49257,Q8N5M9 25 +Inorganic ion transmembrane transport 0.4978060268017146 3.8998502532129784 9.625220144870994e-05 0.4636531556804214 0.0245211233004224 120 Q13586,Q7KZN9,P27105,Q9BPX6,O95202,Q13423,Q4KMQ2,Q9HD23,Q8N4V1,P00403,Q9UHG3,P51790,Q9HD20,Q96RD7,Q96ES6,P12235,P24539,P21796,Q9UM00,P20674,P20020,P98194,Q9Y4W6,Q9H936,Q9UBX3,P23634,Q9H2J7,O75964,P51798,P61619,P56385,Q99623,P13073,O75027,O75323,P03915,Q96PU5,Q15043,Q8TAD4,Q9UMX0,P16615,Q96HE7,P00846,P78417,Q9H0U3,P56134,P05141,P05023,Q9Y6M7,P36542,Q8WWC4,Q9UDW1,Q00535 53 +Glycoprotein biosynthetic process 0.6089438587484006 3.899280537473459 9.647893975484044e-05 0.4644397165640051 0.0245211233004224 62 O43505,Q9H3H5,Q93063,Q8N4A0,Q9BXS4,Q10469,Q9BV10,Q11206,P04843,Q96JB2,O75352,Q7LGA3,Q96AA3,Q9NQX7,P35610,O60502,P46977,Q86YN1,O15118,O75340,Q9H4A6,Q8TCJ2,Q9H5K3,Q86SQ9,Q9BT22,Q8NCH0,Q8WVQ1,Q16706,Q2TAA5,Q9H0U3,P15291,Q9Y287,Q10472 33 +Endomembrane system organization 0.4454577686875361 3.881545347058911 0.0001037947922171 0.4892089927629168 0.0248799961195992 183 Q9NQC3,P50402,Q8NHH9,O95197,Q9NPA0,Q8TBA6,Q6NUK4,Q9BVK6,Q13190,Q9BRK0,Q9Y3B3,P61019,Q4KMQ2,Q15041,P46379,P41440,Q7RTS9,Q00765,Q9NXE4,O43760,Q9BSR8,Q8N4V1,Q9H6H4,Q9Y371,Q96A33,P51790,O75844,Q14108,Q96HR9,Q9H4A6,Q14789,O14966,P49755,Q14155,Q15629,P61619,Q92543,P62820,Q86XL3,O43681,Q15363,Q9P2W9,Q8IXJ6,O94901,Q9H1P3,P16615,Q7Z3C6,O14657,Q7Z3D4,Q9Y3A6,P61026,P57088,P31751,Q16739,Q12981,P49257,O15260,Q8N5M9 58 +Organic acid transmembrane transport 0.7174058353435195 3.859776599774676 0.000113490731072 0.5202804874844814 0.0262325718392209 32 O60831,Q96NB2,P53007,Q15041,P41440,P08183,Q02978,Q8TDW0,O14678,Q9H2D1,P30825,P28288,Q9BQT8,Q9H936,Q9UBX3,Q9H2J7,P23786,Q9H9B4,O95563,Q96QD8,P31751,O75915,Q9UJS0,P50416,O75746,P33121 26 +Mitochondrial respiratory chain complex assembly 0.636707604657659 3.819528284905671 0.0001337071275064 0.579121205701719 0.0290510441177329 45 Q96CU9,Q9Y2R0,O95298,O96000,Q9Y6M9,Q9Y512,O95139,O43676,P03886,Q86Y39,Q9P0J0,Q8N8Q8,Q9Y276,Q9H061,Q9Y375,Q9BSK2,P03915,Q15070,Q69YU5,Q6DKK2,O75306,O43819,O95169,Q9NX14,P51970,O75880 26 +Mitochondrial membrane organization 0.6162043364424565 3.8036854568923366 0.0001425591754584 0.6025589888130338 0.0297626768892648 51 O75431,Q9Y512,P45880,O95202,Q16891,Q9BUR5,Q5XKP0,Q6UXV4,O60313,P12235,Q9P0J0,Q3ZCQ8,P62072,Q9NS69,Q8N8Q8,Q9Y276,Q9H3K2,Q9NVH1,Q9Y4W6,Q969V5,Q15070,Q13505,P52789,P49841,P05141,Q8WWC4,Q53H12,Q8IWA4 28 +Mitochondrial transport 0.5342278508396228 3.7484720349494727 0.0001779151706333 0.6838597795491287 0.0349028538769284 88 O75431,Q99595,Q9Y512,P45880,Q8N4H5,Q9Y371,P51572,P12235,Q3ZCQ8,Q9NS69,Q9P0J0,Q8N8Q8,P62072,Q9Y276,P24539,Q8TB36,Q9H300,Q9UBX3,O75964,P56385,Q969V5,P23786,Q15070,Q6NUK1,P52789,P49841,P00846,O96008,O14925,P56134,Q10713,P05141,O43615,P36542,Q8WWC4,Q53H12,P50416,P49257 38 +Sphingolipid metabolic process 0.6862238159940749 3.710689877498325 0.000206695194223 0.7375958922185888 0.03634705022712 33 P50897,P04062,Q53H12,Q16739,Q9NWW5,O15269,Q96G23,P27544,Q9P035,Q6Y1H2,Q9NZ01,P07602,Q16880,Q9NZJ7,Q13510,P17900,Q06136,O95470 18 +Glycosylation 0.5962155177612751 3.675836663359711 0.0002370711737462 0.7844379632479654 0.03634705022712 55 O43505,Q9H3H5,Q93063,Q8N4A0,Q9BXS4,Q10469,Q9BV10,Q11206,P04843,Q96JB2,O75352,Q96AA3,O75503,O60502,P46977,Q86YN1,O15118,O75340,Q8TCJ2,Q9H5K3,Q86SQ9,Q9BT22,Q16706,Q2TAA5,P04062,Q9H0U3,P15291,Q10472 28 +Glycerolipid biosynthetic process 0.6007544410111397 3.657141681896889 0.0002550434221231 0.8081135630850762 0.03634705022712 50 Q9NTJ5,O43292,Q9HCL2,Q8WUK0,Q8NF37,O15228,Q9Y6K0,Q96N66,Q5H8A4,Q9BTU6,Q8WWI5,O14735,Q6UWP7,Q9BVG9,O95674,Q9H490,Q9UG56,Q9NPH0,Q92643,Q92604,Q6IAN0,Q10713,Q8NCE2,Q99943,Q86UL3,Q96S52,Q9NX62,P35790,Q8WTV0,P33121 30 +Carboxylic acid transport 0.6505239746401655 3.654971707732203 0.0002572103411093 0.8107865335098652 0.03634705022712 37 O60831,P14174,Q96NB2,P53007,Q15041,Q7L0J3,P41440,Q02978,Q8TDW0,P17302,Q9H2D1,P30825,P28288,Q9BQT8,Q9H936,Q9UBX3,Q9H2J7,Q9NZJ7,Q9H9B4,O95563,Q96QD8,O75915,Q9UJS0,P07602,O75746 25 +Localization within membrane 0.431010046425143 3.650266951009744 0.0002619679032971 0.8165252799720996 0.03634705022712 185 Q92544,P43307,Q9BXS4,Q15904,P27105,Q9NPA0,Q9Y512,Q9UNK0,Q6IQ22,Q15006,Q9BRK0,Q7Z3B4,Q86YV9,P46379,Q15041,P41440,P40855,Q8NBU5,Q8N4V1,Q9Y371,Q96A33,Q9HD20,Q8N2H4,Q4J6C6,Q9NS69,Q9P0J0,P56589,Q8N8Q8,P62072,Q9Y276,Q9HD45,Q9H4A6,O15118,Q9BTX1,P98194,O14966,Q99442,Q15629,P23634,P61619,O60725,Q13641,P35613,O43681,P57105,Q15363,Q9NZJ7,Q15070,O15258,O15400,O00264,Q9HD26,Q9Y5J6,P61026,P31751,Q9UGP8,Q53H12,P07602,Q8WWC4,Q13636,P49354,Q00535 62 +Glycerolipid metabolic process 0.5637205061749707 3.644344603357883 0.0002680740451324 0.823636454085394 0.03634705022712 71 Q9BZF1,Q9NTJ5,O43292,Q9HCL2,Q8WUK0,Q8NF37,Q8NCG7,O15228,Q9Y6K0,Q8N2K0,P40939,Q96N66,Q5H8A4,Q9BTU6,Q8WWI5,Q9NXE4,O14735,Q6UWP7,Q9BVG9,O95674,Q9H490,Q96JX3,Q99623,Q9UG56,Q9NPH0,Q92643,Q92604,Q6IAN0,Q10713,Q9UBV2,Q86UL3,Q8NCE2,Q99943,Q96S52,Q96DA6,Q9NX62,P35790,Q53H12,P50416,Q8WTV0 40 +Glycerophospholipid biosynthetic process 0.612268201311032 3.614684277479964 0.0003007138605797 0.8572289230603813 0.03634705022712 45 Q9NTJ5,O43292,Q9HCL2,Q8WUK0,Q8NF37,O15228,Q9Y6K0,Q96N66,Q5H8A4,Q9BTU6,Q8WWI5,O14735,Q6UWP7,Q9BVG9,O95674,Q9H490,Q9UG56,Q9NPH0,Q92643,Q6IAN0,Q10713,Q8NCE2,Q99943,Q86UL3,Q9NX62,P35790 26 +Golgi vesicle transport 0.464527460812309 3.5772751562212433 0.0003471946444622 0.8943299642327082 0.03634705022712 135 Q8NHH9,P24390,Q8TBA6,Q9BVK6,O60499,Q96RQ1,Q13190,Q9Y3B3,P61019,Q9BSR8,P48739,P51572,Q8N2H4,Q4J6C6,O75340,Q9H4A6,Q9Y282,P98194,P11279,O14966,P49755,Q9H0U4,O14653,Q96PC5,P62820,Q15363,Q9P2W9,Q9Y6Y8,O14828,O15258,Q9HD26,P61026,Q9Y3A6,Q12770,O43731,Q9NR31,O15498,O95070,Q969X5,O95249,Q12981,Q5JRA6,P49257,O15260 44 +Carbohydrate derivative transport 0.8177013794230276 3.555425488051558 0.000377367884669 0.91308163142538 0.03634705022712 17 Q96AA3,P41440,O43808,P12236,Q8TB61,P12235,P07602,Q08722,Q9NZJ7,Q9HC21,L0R6Q1,Q86VD7,Q6NUK1,Q8WTV0 14 +Organic acid transport 0.5867085169027934 3.542871696402415 0.0003957952158359 0.9228569433716168 0.03634705022712 51 O60831,P14174,Q96NB2,P53007,Q15041,Q7L0J3,P41440,P08183,Q02978,Q6P4A7,Q8TDW0,P17302,O14678,Q9H2D1,P30825,P28288,Q9BQT8,Q9H936,Q9UBX3,Q9H2J7,P23786,Q9H9B4,O95563,Q96QD8,P31751,O75915,O43808,Q9Y3D6,Q9UJS0,O14975,P50416,O75746,P33121 33 +Glycerophospholipid metabolic process 0.5663410021610737 3.5334819059278635 0.0004101241617744 0.9296918830323369 0.03634705022712 64 Q9BZF1,Q9NTJ5,O43292,Q9HCL2,Q8WUK0,Q8NF37,O15228,Q9Y6K0,Q8N2K0,P40939,Q96N66,Q5H8A4,Q9BTU6,Q8WWI5,Q9NXE4,O14735,Q6UWP7,Q9BVG9,O95674,Q9H490,Q96JX3,Q99623,Q9UG56,Q9NPH0,Q92643,Q92604,Q6IAN0,Q10713,Q86UL3,Q8NCE2,Q99943,Q96S52,Q9NX62,P35790,Q8WTV0 35 +Membrane lipid biosynthetic process 0.7190214697202679 3.4914359087997724 0.0004804317148285 0.9554035586650672 0.03634705022712 27 Q9H490,P04062,O43292,Q16739,O15269,Q96G23,Q11206,Q9P035,Q6Y1H2,P27544,Q8NBX0,Q92643,Q16880,Q13510,Q53H12,Q06136,Q5H8A4,O95470 18 +Endoplasmic reticulum to golgi vesicle mediated transport 0.5346047588838263 3.4612102618313956 0.0005377526279275 0.9692317241043736 0.03634705022712 76 Q8NHH9,P24390,Q9BVK6,Q96RQ1,Q13190,Q9Y3B3,Q96JB2,P61019,Q9BSR8,P51572,O75340,Q9Y282,O14966,P49755,O15027,Q9H0U4,Q9Y5U9,O14653,Q96PC5,P62820,O75396,Q15363,Q9P2W9,Q9Y6Y8,Q9HD26,Q9Y3A6,Q12770,O43731,Q9NR31,O95070,Q969X5,O95249,Q5JRA6,P49257,O15498 35 +Lipid localization 0.5185100480818999 3.4244845888840185 0.0006159667793852 0.981458898115242 0.03634705022712 82 Q9Y3B1,Q00169,Q99720,Q4KMQ2,Q9H6V9,Q96AA3,Q9BUR5,P48739,P08183,P35610,O15118,Q14108,P17900,O14678,O95674,Q96JX3,Q14534,P23786,Q9NZJ7,Q9H1P3,Q9H2V7,Q7Z3C6,P31751,O43808,P04062,Q16739,P07602,O15260,P50416,Q8WTV0 30 +Establishment of protein localization to membrane 0.4819549772665317 3.37791506002382 0.0007303763720574 0.9911622500387868 0.0366433789143845 96 P43307,Q15904,P27105,Q9NPA0,Q9Y512,Q9BRK0,Q15041,P46379,Q8NBU5,P40855,Q8N4V1,Q96A33,Q9HD20,Q8N2H4,Q4J6C6,Q9NS69,Q9P0J0,P56589,Q8N8Q8,P62072,Q9Y276,O15118,Q9H4A6,P98194,Q99442,Q15629,P61619,O60725,O43681,Q15070,Q9HD26,Q9Y5J6,P61026,P31751,Q9UGP8,Q53H12,Q8WWC4,Q13636,Q00535 39 +Carbohydrate derivative biosynthetic process 0.4087054548634209 3.271865219972646 0.0010684049583564 0.9990106015072044 0.0395996398102477 174 O43505,Q9H3H5,Q13126,Q9BXS4,O43292,Q8N4A0,Q9BV10,Q10469,Q11206,O75352,Q5H8A4,Q7LGA3,P50897,Q96AA3,Q9NQX7,P00403,P55263,P35610,O60502,P46977,Q86YN1,O15118,Q15118,O75340,P24539,Q8NBX0,Q53GQ0,Q9H4A6,Q8TCJ2,Q9NZ01,Q9H5K3,Q86SQ9,Q9H490,P04818,O75964,Q8NCH0,Q16706,Q9BT22,P56385,Q6Y1H2,Q92643,Q2TAA5,Q8WVC6,P00846,Q9H0U3,P56134,Q8TB61,Q16739,P15291,P36542,Q16880,Q9Y287,Q10472 53 +Inner mitochondrial membrane organization 0.7254867035036586 3.234063939536058 0.0012204212969308 0.9996305112809104 0.0425177549602763 22 Q13505,Q9BUR5,O75431,Q5XKP0,Q6UXV4,O60313,Q9Y512,Q9P0J0,P62072,O95202,Q8WWC4,Q16891,Q53H12,Q9H3K2,Q9NVH1,Q9Y4W6 16 +Phospholipid biosynthetic process 0.535309201469053 3.213535731170307 0.0013111148352695 0.9997947132624726 0.0427914212582431 63 P14324,Q9NTJ5,Q9HCL2,O43292,Q8WUK0,Q8NF37,O15228,Q9Y6K0,Q96N66,Q5H8A4,Q9BTU6,Q8WWI5,O14735,Q86YN1,O15269,Q6UWP7,Q9BVG9,O95674,Q86SQ9,Q9H490,Q96JX3,Q9UG56,Q9NPH0,Q92643,Q92604,Q6IAN0,Q10713,Q8NCE2,Q99943,Q86UL3,Q9NX62,P35790 32 +Protein transmembrane transport 0.6943643122248101 3.2022551782840503 0.0013635615040605 0.9998538668293164 0.0428396604576704 25 P49755,Q99442,P31751,Q15629,O75381,Q99595,Q07820,P61619,O96008,Q9UGP8,O14925,Q9NS69,O43615,O75298 14 +Cellular ion homeostasis 0.465053790838541 3.1110183438628782 0.0018644335694328 0.9999943161217216 0.0503624632482343 94 Q92544,Q9Y487,Q15904,Q9BPX6,O95202,Q16891,Q7L0J3,P50897,O75503,Q8N511,P51790,P09601,P51572,Q96A33,Q9HD20,Q9UM00,P20020,P98194,Q9Y4W6,P23634,O75027,Q96PU5,Q15043,Q8TAD4,P16615,Q93050,Q96HE7,P78417,P55061,P05023,Q9Y6M7,O43819,Q8WWC4,Q9NWW5,Q96TC7,Q00535,O75880 37 +Nadh dehydrogenase complex assembly 0.6055535582642556 3.101600670618358 0.0019247741326775 0.9999961565577788 0.0503624632482343 33 Q96CU9,Q9H061,Q9Y375,Q9NX14,O95298,O96000,O75306,Q9Y6M9,Q9P0J0,P03915,O95169,O95139,Q9Y276,O43676,Q15070,P03886,Q86Y39 17 +Proton transmembrane transport 0.5529293312428918 3.097203242881687 0.0019535588437469 0.9999968109860304 0.0503624632482343 45 Q7KZN9,Q13423,P51790,P00403,Q96ES6,P12235,P24539,P20674,O75964,P56385,Q99623,P13073,P03915,Q8TAD4,P00846,P56134,P05141,P05023,P36542,Q9UDW1 20 +Ion homeostasis 0.4387883853314687 3.0856042186803543 0.0020313901973894 0.9999980748929328 0.050993821677682 113 Q92544,Q13586,Q9Y487,Q15904,Q9BPX6,Q9Y6N1,O95202,Q16891,Q7L0J3,P50897,O75503,Q8N511,P51790,P09601,P51572,Q96A33,P30519,Q9HD20,P17302,Q9UM00,P20020,P98194,Q9Y4W6,P23634,Q658P3,O75027,Q96PU5,Q15043,Q8TAD4,P16615,Q93050,Q96HE7,P78417,P55061,P05023,Q9Y6M7,O43819,Q8WWC4,Q9NWW5,Q96TC7,Q00535,O75880 42 +Liposaccharide metabolic process 0.7177583559391132 3.083588698755046 0.0020452013289324 0.999998239824754 0.050993821677682 20 Q9H490,P04062,O43292,Q16739,Q11206,Q16880,Q8NBX0,P17900,Q9NWW5,Q5H8A4 10 +Nucleotide transport 0.8074668657409412 3.06593060568167 0.0021699367058143 0.9999992161824416 0.0522710896791031 14 P41440,O43808,Q9BSK2,P12236,Q8TB61,P12235,Q9HC21,Q86VD7,Q08722,Q6NUK1,Q9H2D1 11 +Inorganic anion transport 0.6391276256885459 3.008146960665781 0.0026284599773056 0.999999959976102 0.0592731462478125 28 Q9UBX3,P08183,P51790,Q9UHG3,Q96S66,Q9Y6M7,Q9Y277,P45880,O43681,P21796,Q15043,Q4KMQ2,Q9C0H2 13 +Phospholipid metabolic process 0.4766678273977371 2.997000352765663 0.0027265039782107 0.9999999788162914 0.0601287441635712 84 Q9BZF1,P14324,Q9NTJ5,Q9HCL2,O43292,Q8WUK0,Q8NF37,Q9Y6K0,O15228,Q96N66,P40939,Q8N2K0,Q5H8A4,Q9BTU6,Q8WWI5,Q9NXE4,O14735,Q86YN1,O15269,Q6UWP7,Q9BVG9,O95674,Q86SQ9,Q9H490,Q96JX3,Q99623,Q9UG56,Q9NPH0,Q92643,P37268,Q92604,Q6IAN0,Q10713,Q8NCE2,Q99943,Q96S52,Q86UL3,Q9NX62,P35790,Q8WTV0 40 +Nitrogen compound transport 0.367770459126708 2.9675557397477528 0.0030017785007101 0.9999999964514524 0.0622081664751973 572 Q99595,P43307,P24390,Q15904,Q9UNK0,Q8N4H5,Q6IQ22,Q13190,Q7Z3B4,P61019,O75298,P46379,P50897,Q8WWI5,P13473,Q7Z434,Q4J6C6,Q9NS69,Q9Y277,Q3ZCQ8,Q8N8Q8,P56589,P17302,Q86VD7,Q9H4A6,Q9Y276,Q9Y282,Q9H2D1,Q9H936,Q15629,O14653,Q92543,O60725,O75027,Q9Y5M8,P57105,Q9P2W9,Q9NZJ7,Q9Y6Y8,Q15070,Q9Y3C0,Q9H9B4,O95563,P49841,Q9HD26,Q9Y5J6,O43731,O14925,Q9Y6M1,O15173,Q10713,Q14012,O95070,P07602,Q92945,Q5JRA6,Q13636,Q8N5M9,Q00535,Q15005,Q9Y3E0,Q969Q5,Q9Y679,Q08J23,P51991,P27105,P55786,Q9BRT2,O60499,Q07955,Q9HC21,Q9BRK0,Q96JB2,Q86YV9,Q13546,Q07666,P40855,Q9Y371,Q9HD20,Q8N2H4,Q6P4A7,Q9P0J0,P62072,Q8TDW0,Q14108,Q9H300,Q8TEX9,P22626,P30825,O15027,Q9Y5U9,Q96PC5,P67809,Q96KC8,P41208,O75396,Q9Y6B6,O00170,O14828,O95831,Q7Z4Q2,Q32P28,Q86Y82,Q96QD8,Q9Y3A6,O75915,O14964,Q9Y3D6,Q9UJS0,Q9NR31,P10619,Q14699,Q8TB61,Q9UBV2,Q13432,Q9HCU5,O95249,Q8WWC4,Q96DA6,Q96D46,Q15388,L0R6Q1,P04035,Q08209,O75746,Q92544,Q92973,Q9BRG1,Q9Y5J9,P50402,Q07820,Q8NBM4,Q9Y5L0,Q9BVK6,Q08722,Q9Y3B3,P40939,Q15041,Q7L0J3,P41440,P08183,P51572,Q16850,P12235,O75340,Q9BTX1,Q16836,P98194,O14966,P49755,Q9H2J7,Q9BSK2,P62820,Q9GZP9,Q03519,O43681,Q6NUK1,P61026,O43808,O75381,O96008,O43615,P49257,O15260,O60831,Q96NB2,Q8NFH5,P12236,Q9Y512,Q96CS3,Q8TB36,O14678,O15504,Q9H0U4,Q99442,Q12769,P61619,Q658P3,Q99623,P00367,Q15363,A0AVF1,O15400,O43823,P31751,Q9UGP8,P27824,P05141,Q53H12,P50416,O15498 191 +Sphingolipid biosynthetic process 0.7123153872762921 2.9634496196426885 0.0030421185558526 0.9999999972690046 0.0622081664751973 18 P04062,Q16739,O15269,P27544,Q96G23,Q9P035,Q6Y1H2,Q16880,Q13510,Q53H12,Q06136,O95470 12 +Intracellular protein transmembrane transport 0.6782217678162152 2.934223801320421 0.0033438300725516 0.9999999996149052 0.0647942162561511 22 Q99442,P31751,Q15629,O75381,Q99595,O96008,P61619,Q9UGP8,O14925,Q3ZCQ8,O43615,Q96DA6,Q15388,O95831,O75298,O94826 16 +Chemical homeostasis 0.3877313147862241 2.9313676433789277 0.0033747313795318 0.9999999996849214 0.0651977954875519 181 Q92544,Q13586,Q9NQC3,Q9Y487,Q15904,Q9HCL2,Q9BPX6,Q15067,Q8NF37,Q9Y6N1,Q9BWH2,O95202,Q16891,Q7L0J3,P50897,O75503,Q8N511,P51790,P09601,P51572,Q96A33,P30519,Q9HD20,P35610,O15118,Q9P035,P17302,Q9UM00,P20020,P98194,Q9Y4W6,P23634,Q658P3,O15254,O75027,Q96PU5,Q15043,P52789,Q8TAD4,O95563,P16615,Q93050,Q96HE7,P78417,P04062,P55061,Q16739,P05023,Q9Y6M7,P42785,O43819,Q96TC7,Q8WWC4,O15260,Q9Y6C9,Q9NWW5,Q8WTV0,Q8N5M9,Q00535,O75880 60 +Protein targeting 0.4265272959213463 2.927848704276073 0.0034131608784429 0.9999999997545092 0.0657439797776263 116 Q99595,P43307,Q9Y512,Q8N4H5,Q7Z3B4,Q15041,P46379,P40855,P13473,Q9Y371,P51572,Q3ZCQ8,Q9NS69,Q9P0J0,P62072,Q14108,Q8TB36,Q9H300,Q99442,Q15629,P61619,O60725,Q9Y5M8,P57105,O43681,P31751,O75381,O96008,O14925,Q9UGP8,Q10713,O43615,Q53H12,P49257,Q15005 35 +Protein insertion into membrane 0.5890345887139387 2.9063230340789388 0.0036570369272725 0.9999999999496352 0.0680770487751981 32 Q15629,Q8N4V1,P61619,Q53H12,Q96A33,Q9NPA0,Q9Y512,Q9P0J0,Q9NS69,P62072,Q8N8Q8,Q9Y276,O43681,Q8WWC4,Q15070,P46379 16 +Ph reduction 0.7427492338505022 2.845357690364051 0.0044361576967462 0.9999999999996814 0.0778070802529579 15 P50897,Q93050,O75503,Q8N511,Q9Y487,Q9NWW5 6 +Carbohydrate derivative metabolic process 0.3760068032332066 2.839399912998769 0.0045198471745317 0.999999999999815 0.0787217208075512 275 O43505,P49902,Q9H3H5,Q13126,Q9BXS4,Q9HCL2,O43292,Q9BV10,O60858,Q8N4A0,Q9BRR6,Q11206,Q10469,O75352,Q5H8A4,Q9BTY2,Q7LGA3,P50897,Q7Z2Z2,Q96AA3,Q9NQX7,P00403,P55263,P35610,O60313,O60502,P46977,Q86YN1,O15118,Q15118,O75340,P24539,Q8NBX0,Q53GQ0,Q9H4A6,P17900,Q8TCJ2,Q9NZ01,Q9H5K3,Q9H0U4,Q86SQ9,P15586,Q9H490,P04818,O75964,Q8NCH0,Q16706,Q9BT22,P56385,P62820,O60725,Q9UKV5,Q9NPH0,Q6Y1H2,Q92643,Q2TAA5,P52789,Q8WVC6,P00846,P04062,Q9H0U3,P56134,Q8TB61,Q16739,Q8IWA4,P15291,Q86UL3,P08236,P36542,Q9NX62,Q16880,P04035,Q9Y287,Q9NWW5,Q10472 75 +Metal ion transport 0.4214813755267785 2.832245453617784 0.0046222351881541 0.999999999999905 0.0799869148067751 106 Q13586,Q9BPX6,O95202,Q4KMQ2,Q8N4V1,Q9HD20,O75844,Q96RD7,P21796,Q9UM00,P20020,P98194,Q9Y4W6,P23634,Q9H2J7,P61619,Q658P3,O75027,O75323,Q96PU5,Q15043,Q9H9B4,Q8TAD4,Q9UMX0,Q96QD8,P16615,Q96HE7,Q96BY9,Q9H0U3,P78417,O15173,P55061,P05023,Q9Y6M7,Q8WWC4,Q00535 36 +Amino acid transmembrane transport 0.7159954174899285 2.8278134768118734 0.0046867104744323 0.9999999999999376 0.0806712505067188 16 Q9H936,O60831,O75915,Q96NB2,Q9H2J7,Q9UJS0,Q8TDW0,Q9H9B4,Q15041,P30825,Q96QD8 11 +Metal ion homeostasis 0.4577575572404685 2.8183873549683898 0.0048265543331553 0.9999999999999748 0.0823615785712651 86 Q13586,Q9Y487,Q15904,Q9BPX6,Q9Y6N1,O95202,Q16891,Q7L0J3,Q8N511,P09601,P51572,Q96A33,P30519,Q9HD20,Q9UM00,P20020,P98194,Q9Y4W6,P23634,Q658P3,O75027,Q96PU5,Q15043,Q8TAD4,P16615,Q96HE7,P78417,P55061,P05023,O43819,Q8WWC4,Q96TC7,Q00535,O75880 34 +Cellular monovalent inorganic cation homeostasis 0.6117729989702426 2.810090011989752 0.0049527646167508 0.9999999999999888 0.082930545080559 28 P50897,Q92544,O75503,Q8N511,Q93050,P51790,Q9Y487,P05023,Q9Y6M7,Q96PU5,Q9NWW5 11 +Endoplasmic reticulum tubular network organization 0.7594030173149244 2.809690347099516 0.0049589185639951 0.9999999999999892 0.082930545080559 14 P61026,Q9NQC3,Q8NHH9,O95197,Q9H6H4,Q6NUK4,Q9BRK0,Q15041 8 +Regulation of hormone levels 0.4996835787422462 2.8024525714108326 0.0050715672888217 0.9999999999999948 0.0841620089570623 59 Q9HBH5,Q9BRT2,P40939,O95470,Q8NBN7,O75844,P17302,Q53GQ0,Q16836,P62820,Q92543,P00367,Q15043,Q8TC12,Q8TAD4,O95563,Q9Y394,P42892,Q96HE7,Q9UBM7,P05023,Q8NBQ5,P50416,P16435,Q8N5M9 25 +Amyloid precursor protein metabolic process 0.6778068643733152 2.792717415068462 0.0052267330053008 0.999999999999998 0.0862422671927279 19 P49755,Q9NQC3,Q9NQX7,O95197,Q16799,Q15392,Q9Y287,O75298 8 +Sterol metabolic process 0.5415337226099767 2.7879956056171795 0.0053035263199483 0.9999999999999988 0.0862422671927279 38 P14324,Q15800,Q12770,Q9UBM7,O75845,P04062,P35610,P37268,Q14534,Q15392,Q16850,Q9NWW5,O15118,P04035,Q14739,P16435,Q8WTV0 17 +Oxidative phosphorylation 0.4839652762939325 2.7795228063490875 0.0054438830708762 0.9999999999999996 0.0883027850494018 69 O95298,Q7KZN9,O96000,Q9Y6M9,O14949,O95139,O43676,P03886,P00403,P24539,Q9H3K2,P20674,Q9Y375,O75208,O75964,Q9BSK2,P56385,P13073,O75323,P03915,P00846,P56134,O75306,O95169,P36542,Q9UDW1,P51970 27 +Protein n linked glycosylation 0.6231221868399329 2.7724410496346583 0.005563759578252 0.9999999999999998 0.0895056401485044 26 Q96AA3,Q9H3H5,Q86SQ9,Q93063,Q9H0U3,Q9BT22,P15291,Q10469,Q9BV10,P46977,Q86YN1,O75340,Q2TAA5,Q8TCJ2,O75352 15 +Cytochrome complex assembly 0.7745562172469159 2.770959966628742 0.0055891298038184 0.9999999999999998 0.0895056401485044 13 Q69YU5,Q9Y2R0,Q6DKK2,Q9BSK2,P53701,Q7KZN9,O43819,Q8N8Q8,Q15070,O75880 10 +Protein localization to endoplasmic reticulum 0.5446609041696715 2.767130875841017 0.0056552047145854 1.0 0.0897070708646989 36 Q99442,P61026,Q15629,Q9NQC3,Q9UGP8,O43731,Q8NBM4,P61619,P24390,P51572,O43292,O43681,Q9Y5M8,O15258,P46379,Q15005 16 +Mitochondrial fusion 0.6765101642847434 2.734159742607896 0.0062539695491483 1.0 0.0955800053874814 17 Q8N2A8,Q9NX63,Q8NAN2,O60313,Q969V5,Q8TB36,Q99536,Q8IWA4,Q9Y6C9,Q9H300,Q9Y4W6 11 +Hormone metabolic process 0.6170477686651461 2.7293208310203205 0.0063464925758414 1.0 0.0955829159924794 26 P42892,Q96HE7,Q9UBM7,Q8NBN7,Q9HBH5,O75844,Q9Y394,P05023,Q8TC12,Q53GQ0,Q8NBQ5,P16435,Q8TAD4,O95470 14 +Organelle fusion 0.4974698538013943 2.698436569860854 0.0069666012712663 1.0 0.1015491969090898 50 O60499,Q9UNK0,Q99536,Q13190,Q9BSR8,O60313,Q8TB36,Q9H300,Q9Y4W6,Q8N2A8,Q9NX63,O14653,Q969V5,O75396,O15400,Q86Y82,P31751,Q8NAN2,O95249,Q12981,Q8IWA4,Q9Y6C9 22 +Vacuolar acidification 0.7960642527074971 2.663736662649765 0.0077278031793057 1.0 0.1080223373141834 11 P50897,Q93050,Q8N511,Q9Y487,Q9NWW5 5 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.5995489097846356 2.660004336661456 0.0078139645385681 1.0 0.1086115471722363 27 P49755,P24390,Q969X5,Q96RQ1,Q9P2W9,Q12981,Q9H4A6,O15258,Q9Y282 9 +Nucleotide transmembrane transport 0.7937459012408327 2.652150024588735 0.0079980995385979 1.0 0.1108430411430538 11 P41440,O43808,Q9BSK2,P12236,Q8TB61,P12235,Q86VD7,Q9H2D1 8 +Monovalent inorganic cation homeostasis 0.5569312142843438 2.65053560790198 0.0080364255541669 1.0 0.1108992456003592 32 P50897,Q92544,O75503,Q8N511,Q93050,P51790,Q9Y487,P05023,Q9Y6M7,Q96PU5,Q9NWW5 11 +Membrane lipid catabolic process 0.7716299172718837 2.644157073383053 0.0081894643045985 1.0 0.1125197962606765 12 P50897,P04062,Q13510,P17900,O95470 5 +Protein processing 0.5133364329834545 2.643473566438282 0.0082060172798268 1.0 0.1125197962606765 42 P42892,P67812,O75503,Q9BXS4,Q10713,Q15392,O75844,Q9UG56,Q9H300,Q8TAD4,Q15005 11 +Amyloid precursor protein catabolic process 0.7279887822314287 2.6376757732301144 0.0083476351481324 1.0 0.1139786807567784 14 Q9NQC3,O95197,Q16799,Q15392,O75298 5 +Endoplasmic reticulum membrane organization 0.8252583969570979 2.6336537194792133 0.0084471588934944 1.0 0.1142897437345066 9 Q00765,Q9NQC3,Q8NHH9,Q12981,Q9P2W9,Q15041 6 +Purine nucleotide transport 0.7887344236836725 2.62704634275509 0.0086129603056839 1.0 0.1158899773355226 11 P41440,O43808,P12236,Q8TB61,P12235,Q08722,Q86VD7,Q6NUK1 8 +Regulation of lipid metabolic process 0.4860757071444663 2.6153963094452672 0.0089123977549083 1.0 0.1189299758139526 54 Q8NF37,Q8NCG7,Q96N66,O75844,Q96G23,Q15118,Q99623,Q9NZJ7,Q92604,P11802,P31751,Q12770,Q9UBM7,P05023,P07602,Q13510,Q9H6K4,P50416,P16435,Q8WTV0 20 +Dicarboxylic acid transport 0.6417264751463284 2.6045012738105537 0.0092008078943768 1.0 0.1193517235224415 20 P41440,O60831,Q9H936,Q9BQT8,Q9UBX3,O75915,Q9UJS0,Q02978,Q8TDW0,P17302,Q9H2D1,Q15041 12 +Calcium ion import 0.7634738883591501 2.6018924026503973 0.0092710934491078 1.0 0.1193517235224415 12 P23634,O75844,Q9BPX6,Q8WWC4,P21796,Q9Y4W6,P16615 7 +Vitamin transport 0.8310593314525723 2.581122526313251 0.0098479622603482 1.0 0.1237592461145121 8 P41440,P38435,P04062,Q9HC21,Q9H2D1,Q8WTV0 6 +Protein localization to mitochondrion 0.4736038372985579 2.5680259793977434 0.0102279490391745 1.0 0.1267054924951758 62 Q99595,Q9Y512,Q8N4H5,P51572,Q9Y371,Q9P0J0,Q9NS69,P62072,Q8N8Q8,Q9H300,Q15070,P52789,O96008,O14925,Q10713,O43615,Q8WWC4,P49257,Q9Y6C9 19 +Ceramide metabolic process 0.621647234327058 2.560426490194528 0.0104543777800407 1.0 0.1267054924951758 22 P04062,Q53H12,Q16739,O15269,Q96G23,P27544,Q16880,Q13510,P17900,Q9NWW5,O95470 11 +Amino acid transport 0.6074086880686992 2.5578148141992942 0.0105332168279654 1.0 0.1273345585612985 24 O60831,Q9H936,Q96NB2,O75915,Q9H2J7,Q9UJS0,Q6P4A7,Q8TDW0,P17302,Q9H9B4,P30825,Q15041,Q7L0J3,Q96QD8 14 +Steroid biosynthetic process 0.5037027659849793 2.5548614494201023 0.0106230072884772 1.0 0.1280299872830995 42 P14324,Q15392,Q9UHQ9,Q14739,Q15800,Q16850,Q53GQ0,Q9UHI6,O75845,Q14534,P37268,Q9H1P3,Q12770,Q9UBM7,P05023,Q13510,Q8NBQ5,P04035,P16435 19 +Atp synthesis coupled electron transport 0.4972016537212001 2.5518508657281656 0.0107152373527998 1.0 0.1289015170024552 44 P00403,O95298,Q7KZN9,O96000,P13073,Q9Y6M9,P03915,O14949,O43676,Q9H3K2,P03886 11 +Glycolipid biosynthetic process 0.7714757699768685 2.53998875958146 0.0110856031580932 1.0 0.1326174189263948 11 Q9H490,O43292,Q16739,Q11206,Q16880,Q8NBX0,Q5H8A4 7 +Lytic vacuole organization 0.6097586131440884 2.527935861635711 0.0114735310076943 1.0 0.1336003700054736 23 P50897,O75503,Q8N511,O14773,P04062,Q14108,Q9NWW5 7 +Vacuole organization 0.478950711049164 2.515356129384971 0.0118912199354939 1.0 0.1336003700054736 50 P50897,O75503,Q7Z3C6,Q8N511,O14773,P04062,Q9Y371,P62820,P11117,Q14108,Q9NWW5,Q9UMX0,P16615 13 +Regulation of autophagy 0.4237439257826242 2.5134737490995063 0.0119548674677716 1.0 0.1336003700054736 91 Q07820,Q9Y487,Q9BXS4,O60858,P09601,Q9Y371,O75844,P12235,O15118,P21796,Q9H300,Q86UE4,Q9NZJ7,Q8IXJ6,Q93050,P04062,P10619,P27544,P07602 19 +Oligosaccharide lipid intermediate biosynthetic process 0.7832420018680556 2.5128177931864504 0.0119771176787364 1.0 0.1336003700054736 10 Q96AA3,Q9H3H5,Q9BT22,Q9BV10,Q86YN1,O75340,Q2TAA5,O75352 8 +Protein targeting to mitochondrion 0.4757304622757862 2.472352632308571 0.0134227041611525 1.0 0.1443052181577728 48 Q9Y5J9,Q99595,P55786,Q9Y512,Q8N4H5,P51572,Q9Y371,Q9P0J0,Q3ZCQ8,P62072,Q8TB36,Q9NS69,Q9H300,O00170,O95831,Q9Y5J6,O96008,Q9Y3D6,O14925,Q10713,O43615,Q96DA6,Q15388,Q53H12,P49257 25 +Regulation of amyloid precursor protein catabolic process 0.7371975950154006 2.464203425514478 0.0137318151500807 1.0 0.1454538586764686 12 O95197,Q16799,Q9NQC3,O75298 4 +Regulation of cellular ph 0.5996617604793809 2.457863865766125 0.0139766143830601 1.0 0.1455916286708231 23 P50897,Q92544,O75503,Q8N511,Q93050,P51790,Q9Y487,Q9Y6M7,Q9NWW5 9 +Regulation of ph 0.5996617604793809 2.457863865766125 0.0139766143830601 1.0 0.1455916286708231 23 P50897,Q92544,O75503,Q8N511,Q93050,P51790,Q9Y487,Q9Y6M7,Q9NWW5 9 +Lipid storage 0.6320369309091178 2.4571744599697323 0.0140034663370109 1.0 0.1455916286708231 17 Q9BZF1,Q9Y679,P04062,P35610,Q14534,P17900,P50416,Q8WTV0,O95674,Q9H6V9 10 +Amyloid beta metabolic process 0.7358133372810216 2.4568846218399587 0.0140147689527074 1.0 0.1455916286708231 12 O95197,Q16799,Q9NQC3,O75298 4 +Respiratory electron transport chain 0.4677645365852911 2.453953785006094 0.0141295139194417 1.0 0.14654842001062 57 P00403,O95298,Q7KZN9,O96000,P21912,P04062,P13073,Q9Y6M9,P03915,O14949,O43676,Q9H3K2,P03886 13 +Neutral lipid metabolic process 0.650179464150902 2.435484003512155 0.0148718821512172 1.0 0.1506272633531739 16 Q9HCL2,Q9UBV2,Q86UL3,Q8NCG7,Q92604,Q8N2K0,Q8WTV0,Q96N66 8 +Phospholipid transport 0.6213579378932863 2.4329557169741327 0.0149761323627519 1.0 0.150933255150378 19 Q7Z3C6,P48739,Q9Y3B1,Q00169,P08183,Q14108,Q4KMQ2,Q8WTV0 8 +Cristae formation 0.7828051899080255 2.429304194470927 0.0151278338102827 1.0 0.150933255150378 9 Q9BUR5,Q5XKP0,Q6UXV4,Q9Y512,O95202,Q16891,Q9NVH1 7 +Sterol biosynthetic process 0.5886111307183843 2.425084443342636 0.0153048263487993 1.0 0.1516094644750302 24 P14324,Q15800,Q12770,Q9UBM7,O75845,P37268,Q14534,Q15392,Q16850,P04035,Q14739,P16435 12 +Vitamin transmembrane transport 0.9113408521303276 2.423735521049029 0.0153617885771619 1.0 0.1517600383125663 6 P38435,P04062,Q9HC21,Q9H2D1,Q8WTV0 5 +Phosphatidylinositol metabolic process 0.5746742739406988 2.4222684628709827 0.0154239512181963 1.0 0.1517600383125663 26 Q9BTU6,Q9H490,Q9NTJ5,O43292,O14735,Q10713,Q8NCE2,Q6UWP7,Q92643,Q9NX62,Q92604,Q96N66,Q5H8A4 13 +Import across plasma membrane 0.6186291125335444 2.4151592429666993 0.0157283316406426 1.0 0.1539996405117087 19 P41440,P31751,O75915,P23634,Q8IWT6,P05023,Q8TDW0,Q15043,Q9BXP2,P54709,Q15041,P30825,P33121 13 +L amino acid transport 0.7277868416400486 2.4143172294500426 0.0157647300284449 1.0 0.1541228591300536 12 Q9H936,O60831,O75915,Q9UJS0,Q9H9B4,Q15041,P30825,Q96QD8 8 +Establishment of protein localization 0.3426951673430898 2.3983907253715864 0.0164672890879606 1.0 0.157190535348984 516 Q99595,P43307,P24390,Q15904,Q9UNK0,Q8N4H5,Q6IQ22,Q13190,Q7Z3B4,P61019,O75298,P46379,P50897,Q8N4V1,P13473,Q7Z434,Q4J6C6,Q9NS69,Q3ZCQ8,P56589,Q8N8Q8,Q9Y276,Q9H4A6,Q9Y282,Q15629,O14653,Q92543,O60725,Q9Y5M8,P57105,Q9P2W9,Q9Y6Y8,Q9Y3C0,Q15070,O95563,P49841,Q9HD26,Q9Y5J6,O43731,O14925,Q10713,Q14012,O95070,Q5JRA6,Q13636,Q8N5M9,Q00535,Q15005,Q9Y3E0,Q969Q5,Q9Y679,P27105,Q9NPA0,P55786,Q9BRT2,O60499,Q9BRK0,Q15006,Q96JB2,Q86YV9,P40855,Q9Y371,Q96A33,Q9HD20,Q8N2H4,Q9P0J0,P62072,Q14108,Q9H300,Q8TEX9,O15027,Q9Y5U9,Q96PC5,Q96KC8,P41208,O75396,Q9Y6B6,Q9H1Z9,O00170,O14828,O95831,Q7Z4Q2,P52789,Q32P28,Q86Y82,Q9Y3A6,O75915,O14964,Q9Y3D6,Q9NR31,P10619,Q14699,Q9UBV2,Q13432,Q9HCU5,O95249,Q8WWC4,Q96DA6,Q96D46,Q15388,P04035,Q08209,Q92544,Q92973,Q9BRG1,Q9Y5J9,P50402,Q07820,Q8NBM4,Q9Y5L0,Q9BVK6,Q9Y3B3,P40939,Q15041,P51572,Q16850,O15118,O75340,Q9BTX1,Q16836,P98194,P11279,O14966,P49755,P62820,Q9GZP9,Q03519,O43681,P61026,O75381,O96008,O43615,P49257,O15260,O60831,Q8NFH5,Q9Y512,Q8NBU5,Q96CS3,Q8TB36,O15504,Q9H0U4,Q99442,Q12769,P61619,Q658P3,Q99623,P00367,Q15363,A0AVF1,O15400,O43823,P31751,Q9UGP8,P27824,Q53H12,P50416,O15498 158 +Atp transport 0.8476966468191853 2.3963295684012573 0.0165601928732626 1.0 0.1576140709937581 7 O43808,P12236,P12235,Q08722,Q86VD7,Q6NUK1 6 +Regulation of mitochondrion organization 0.4663073107198907 2.3939613743119184 0.0166675039414172 1.0 0.1583672423730851 51 Q96A26,Q969V5,P12235,Q9UG56,P27544,P21796,Q9H4A6,Q9H3K2,Q9H300,Q9Y6C9 10 +Steroid metabolic process 0.4549947001450712 2.3928707166080234 0.016717130437668 1.0 0.1583672423730851 64 P14324,Q15392,Q14739,O95470,Q15800,P35610,Q16850,O15118,Q53GQ0,O75845,P38435,Q14534,P37268,Q9H1P3,Q12770,Q9UBM7,P04062,P05023,P16435,Q13510,Q8NBQ5,P04035,Q9NWW5,Q8WTV0 24 +Negative regulation of amyloid precursor protein catabolic process 0.7749901274574117 2.391119005602967 0.0167971073382053 1.0 0.1583672423730851 9 O95197,Q16799,Q9NQC3,O75298 4 +Purine containing compound transmembrane transport 0.7738742269811288 2.385652045140106 0.0170488732825928 1.0 0.1587630329279726 9 P41440,O43808,P12236,Q8TB61,P12235,Q86VD7 6 +Autophagy of mitochondrion 0.4997472002806581 2.3756569589476144 0.0175177402222566 1.0 0.1621957292109367 36 Q7Z3C6,P04062,Q99623,Q969V5,P52789,P12235,P27544,Q9BWH2,P21796,Q9H300 10 +Amyloid beta formation 0.7536917526884879 2.3651240237376063 0.0180240338387696 1.0 0.1661702948782291 10 O95197,Q16799,Q9NQC3,O75298 4 +Protein localization to extracellular region 0.4547201275887979 2.3554008760033924 0.01850273279802 1.0 0.1702310678870459 61 Q9BRT2,Q6IQ22,P40939,Q86YV9,Q9NV70,Q16850,Q9H4A6,Q16836,P49755,Q9Y5U9,Q96PC5,Q658P3,Q92543,Q96KC8,P00367,O95563,Q32P28,P61026,P04035,P27824,Q9UBV2,Q9HCU5,Q08209,Q5JRA6,P50416,Q8N5M9 26 +Phosphatidylglycerol metabolic process 0.6729850616932722 2.3273974396128234 0.0199441219137674 1.0 0.1805291706655988 14 Q96JX3,Q99623,Q9HCL2,Q8NF37,P40939,Q92604,O95674 7 +Protein transmembrane import into intracellular organelle 0.6903950165880368 2.315769357055683 0.0205708651856304 1.0 0.1849092215019448 13 O75381,Q99595,O96008,O14925,Q3ZCQ8,O43615,Q96DA6,Q15388,O95831,O94826 10 +Process utilizing autophagic mechanism 0.3624519426641521 2.2936175394501377 0.0218124770241412 1.0 0.1930143026682725 161 Q969Q5,Q07820,Q9Y487,Q9BXS4,O60858,Q9BWH2,P09601,Q9Y371,O75844,O15269,P12235,O15118,P21796,Q5T8D3,Q9Y6I9,Q9H300,Q9H0U4,P62820,Q99623,Q969V5,Q86UE4,Q9NZJ7,Q8IXJ6,P52789,Q9UMX0,P16615,Q7Z3C6,Q93050,P04062,P10619,P55061,O14681,P27544,P07602 34 +Respiratory chain complex iv assembly 0.824819805703556 2.2929675589922205 0.0218498727217972 1.0 0.1930143026682725 7 Q9Y2R0,Q7KZN9,O43819,Q8N8Q8,Q15070,O75880 6 +Aminoglycan metabolic process 0.6048751438837235 2.2911730322204753 0.0219534080331857 1.0 0.1934477088516304 18 O43505,P15586,Q8NCH0,Q11206,P08236,Q9NX62,Q9NWW5,Q7LGA3 8 +Phosphatidylinositol biosynthetic process 0.5759373136079482 2.290901558230003 0.0219691078501156 1.0 0.1934477088516304 23 Q9H490,Q9NTJ5,O43292,O14735,Q10713,Q9NX62,Q96N66,Q5H8A4 8 +Glycosphingolipid metabolic process 0.7383235210368766 2.287248337342827 0.0221813320874781 1.0 0.1950510615083679 10 P04062,Q9NWW5,Q16739,P17900 4 +Organophosphate biosynthetic process 0.3537306033270062 2.2793283520450713 0.022647553872936 1.0 0.1983423121321273 171 P43490,Q9NTJ5,Q9HCL2,O43292,Q8NF37,Q9Y6K0,O15228,Q96N66,Q5H8A4,P50897,P00403,P35610,O14735,Q86YN1,P24539,Q53GQ0,Q9BVG9,Q9NZ01,O95674,Q9H490,Q96JX3,O75964,P56385,Q9UG56,Q9NPH0,Q6Y1H2,Q92604,Q8WVC6,P00846,P56134,Q10713,Q8TB61,Q86UL3,P36542,Q9NX62 35 +Cobalt ion transport 0.9715269086357968 2.264010151254519 0.023573490433761 1.0 0.2045142494467844 2 Q8N4V1 1 +Phosphatidic acid metabolic process 0.7641325669929643 2.2628108197767016 0.0236473536504919 1.0 0.2048804187764177 8 Q9NPH0,Q8NF37,Q9HCL2,O15228 4 +Calcium ion import into sarcoplasmic reticulum 0.97058823529412 2.2599606728311694 0.0238236917416396 1.0 0.2061322633046684 2 O75844 1 +Inorganic anion transmembrane transport 0.7312601107638049 2.251209180038719 0.024372291743151 1.0 0.2094512291167063 10 Q9UBX3,P51798,P51790,Q9UHG3,Q02978,Q9BXP2,Q4KMQ2 7 +Cellular homeostasis 0.369663659666251 2.2480982585449616 0.0245699251073194 1.0 0.2094512291167063 145 Q92544,Q9NQC3,Q07820,Q9Y487,Q15904,Q9BPX6,Q9BWH2,O95202,Q16891,Q4KMQ2,Q7L0J3,P50897,O75503,Q8N511,P51790,P09601,P13473,Q96A33,Q9HD20,P51572,Q9UM00,P20020,P98194,Q9Y4W6,P23634,O75027,Q96PU5,Q15043,P52789,Q8TAD4,O95563,P16615,Q93050,Q96HE7,P78417,P55061,P05023,Q9Y6M7,O43819,Q96TC7,Q8WWC4,Q9NWW5,Q8N5M9,Q00535,O75880 45 +Regulation of toll like receptor signaling pathway 0.7455519264288143 2.2456710895115903 0.0247250832888077 1.0 0.2094512291167063 9 P41440,Q9NPR9,Q9NQC3 3 +Regulation of lysosomal lumen ph 0.8113247761597908 2.2314030819190016 0.0256544408995589 1.0 0.2153508968896827 7 P50897,Q8N511,Q9NWW5 3 +Lysosomal lumen acidification 0.8638313122533574 2.2207370223292484 0.0263687783254946 1.0 0.2202825350475906 6 P50897,Q8N511,Q9NWW5 3 +Transition metal ion homeostasis 0.5523879941099675 2.2080837600885115 0.0272384348579044 1.0 0.2236055158468727 25 Q8N511,P09601,Q9Y487,Q658P3,Q15904,P30519,O43819,Q15043,Q8TAD4,O75880 10 +Regulation of membrane lipid distribution 0.752511325757207 2.2062667425253353 0.027365328544104 1.0 0.2236055158468727 8 Q96AA3,Q4KMQ2,P08183 3 +Tetrapyrrole metabolic process 0.5816642907059101 2.2053448605446304 0.0274299041278649 1.0 0.2236055158468727 20 Q9P0S9,P09601,Q7KZN9,P30519,P22830,P36551,O00264,O14678 8 +Connective tissue development 0.5456290794388144 2.20526959620321 0.0274351820111884 1.0 0.2236055158468727 26 P11802,Q8N0X7,P43490,Q9C0E8,P04818,P35610,Q92543,O15173,O75844,Q15043,Q9NX62,P16435 12 +Ceramide biosynthetic process 0.6887920192968295 2.2043243216253523 0.0275015436671988 1.0 0.2236055158468727 12 P04062,Q16739,O15269,P27544,Q96G23,Q16880,Q13510,Q53H12 8 +Proteoglycan metabolic process 0.7499444214597057 2.1937259880270465 0.0282551143678364 1.0 0.2272037423718899 8 Q8NCH0,Q8WVQ1,Q9NX62,Q7LGA3 4 +Lipid glycosylation 0.9552565707133917 2.193624684331206 0.0282624023433739 1.0 0.2272037423718899 2 P04062 1 +Lactation 0.7195884952708247 2.1913160314608446 0.0284289307354836 1.0 0.227712920445607 10 Q9UNS2,P00403,Q86UL3,Q13505,P52789 5 +Intracellular protein transport 0.3321816901118118 2.1852900933955213 0.0288675832999365 1.0 0.2302337160838764 325 Q99595,P43307,Q15904,Q9UNK0,Q8N4H5,Q13190,Q7Z3B4,O75298,P46379,P13473,Q7Z434,Q9NS69,Q3ZCQ8,P56589,Q8N8Q8,Q9Y276,Q9Y282,Q15629,O60725,Q9Y5M8,P57105,Q9P2W9,Q9Y6Y8,Q15070,P49841,Q9Y5J6,O14925,Q10713,Q14012,Q13636,Q00535,Q15005,Q969Q5,Q9Y679,P27105,P55786,O60499,Q9BRK0,Q96JB2,P40855,Q9Y371,Q9P0J0,P62072,Q14108,Q9H300,Q8TEX9,O15027,Q9Y6B6,O00170,O95831,Q7Z4Q2,Q86Y82,Q9Y3A6,O14964,Q9Y3D6,Q9NR31,P10619,Q14699,Q9UBV2,Q9HCU5,Q8WWC4,Q96DA6,Q15388,Q08209,Q92544,Q92973,Q9BRG1,Q9Y5J9,P50402,Q8NBM4,Q9Y5L0,Q9BVK6,Q9Y3B3,Q15041,P51572,O75340,O14966,P49755,P62820,Q9GZP9,O43681,O75381,O96008,O43615,P49257,O15260,Q8NFH5,Q9Y512,Q96CS3,Q8TB36,O15504,Q9H0U4,Q99442,P61619,Q99623,Q15363,O15400,P31751,Q9UGP8,Q53H12 100 +Transition metal ion transport 0.6484051156702196 2.1848702818317123 0.0288983590460194 1.0 0.2302337160838764 14 Q8N4V1,Q658P3,O15173,Q9HD20,O75027,Q15043,P98194,Q8TAD4 8 +Regulation of release of cytochrome c from mitochondria 0.7028953380732121 2.1845547368022458 0.0289215097614634 1.0 0.2302337160838764 11 Q9H300,Q96A26,Q9H3K2 3 +Regulation of protein exit from endoplasmic reticulum 0.7479648768883032 2.184042129956753 0.0289591524234278 1.0 0.2302501652142812 8 Q9NR31,Q92544,P51572,Q8NBM4 4 +Phosphatidylcholine acyl chain remodeling 0.9527534418022529 2.1827598642314823 0.0290534987973041 1.0 0.2307168640688985 2 Q8NF37 1 +Regulation of glycoprotein metabolic process 0.7010126714078055 2.1745794908183553 0.0296616426112148 1.0 0.2349695850425734 11 Q9NQX7,P35610,P62820,Q9BXS4,Q9Y287 5 +Lipoprotein metabolic process 0.5817765637465553 2.1710386205066 0.0299282531192053 1.0 0.2365026302655639 19 P50897,Q9H490,P04062,O43292,Q16739,Q8N2K0,Q5H8A4 7 +Determination of adult lifespan 0.851986274702674 2.1693944083883 0.0300527531294854 1.0 0.236865936319553 6 O75844 1 +L alpha amino acid transmembrane transport 0.7152574031753094 2.1689823564912767 0.0300840234324277 1.0 0.236865936319553 10 Q9H936,O60831,O75915,Q9UJS0,Q15041,P30825 6 +Cellular hormone metabolic process 0.6248186133071756 2.157604314534342 0.0309586089692019 1.0 0.2416937481889931 15 P42892,Q8NBN7,Q9HBH5,Q8TC12,Q53GQ0,Q8NBQ5,Q9Y394,O95470 8 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.6426161058686517 2.150948437928553 0.0314802697121563 1.0 0.2448801749724469 14 Q9BXK5,Q96A26,Q9NZJ7,Q969V5 4 +Cartilage development 0.6037883683021673 2.147210516115908 0.0317765258840352 1.0 0.2459055415199665 16 P04818,Q9C0E8,Q92543,O75844,Q9NX62,Q15043,P16435 7 +Triglyceride metabolic process 0.678317311228079 2.1470060607252703 0.0317927991146718 1.0 0.2459055415199665 12 Q9HCL2,Q9UBV2,Q86UL3,Q8NCG7,Q92604,Q96N66,Q8WTV0 7 +Cellular transition metal ion homeostasis 0.5726530124040552 2.1437973117238065 0.0320491308422028 1.0 0.246344388136267 20 Q8N511,P09601,Q9Y487,Q15904,O43819,Q15043,Q8TAD4,O75880 8 +Regulation of protein secretion 0.467380665315925 2.1423468878533987 0.0321655784050018 1.0 0.2466535822715311 39 Q9NV70,P49755,Q9Y5U9,O95563,P04035,Q96KC8,Q16850,Q9BRT2,P00367,P50416,Q08209,Q8N5M9,Q9H4A6,P40939,Q16836,Q32P28 16 +Porphyrin containing compound metabolic process 0.5818480513068949 2.132957866388826 0.0329281826944589 1.0 0.2504244399512789 17 Q9P0S9,P09601,Q7KZN9,P30519,P22830,P36551,O00264 7 +Azole transmembrane transport 0.9408635794743424 2.1310222868563833 0.0330873061606773 1.0 0.2510446019600278 2 Q9HC21 1 +Positive regulation of i kappab kinase nf kappab signaling 0.4680269233283132 2.1273049532766297 0.0333947534734133 1.0 0.252430707179918 38 Q9Y3E0,O43657,P09601,Q8TB61,Q969V5,O60858,Q86UE4 7 +Cerebellar purkinje cell layer formation 0.9399249061326695 2.126928712094874 0.0334260068067351 1.0 0.252430707179918 2 P04062 1 +Vitamin d metabolic process 0.9383604505632082 2.1201031821184317 0.0339973446704449 1.0 0.2558497845431621 2 P04062 1 +Alcohol biosynthetic process 0.4729702440794973 2.115775785454272 0.0343638814781166 1.0 0.2568726483807542 35 P14324,Q15800,Q12770,Q9UBM7,O75845,P04062,P37268,Q15392,Q16850,O15269,Q13510,P04035,Q14739,P16435 14 +Copii coated vesicle budding 0.5513822091827567 2.1146140846592494 0.0344628522377175 1.0 0.2568726483807542 23 P49755,Q12770,Q9UBV8,Q9NR31,P62820,O95486,Q9HCU5,O75340,Q15363,Q9Y6B6,Q5JRA6,P55735,O15027 13 +Secretion 0.358649345276058 2.101931194553728 0.0355593034821504 1.0 0.2612256664432208 149 P14174,Q9UNS2,Q9BRT2,Q9H7Z7,Q6IQ22,P40939,Q9BRK5,Q7L0J3,P50897,O43760,P00403,P09601,Q16850,Q4J6C6,P17302,Q9H4A6,Q16836,P11279,P49755,Q96PC5,Q658P3,Q92543,P62820,Q96KC8,P00367,Q9Y3C0,Q13505,P52789,O95563,P49841,P16615,Q32P28,P61026,P04035,P27824,Q92905,Q9UBV2,P50416,Q86UL3,Q5JRA6,Q13636,P55327,O15498,Q8N5M9,Q00535 45 +Protein maturation 0.4281855530784871 2.096446754875687 0.0360425785321152 1.0 0.2638579393468451 64 P42892,P67812,O75503,Q9BXS4,Q10713,Q15392,O75844,Q9BU23,Q9UG56,Q9H300,Q8TAD4,Q15005 12 +Lipid translocation 0.7812850745105137 2.0927831670462154 0.0363685151216817 1.0 0.2647660628431091 7 Q96AA3,Q4KMQ2,P08183 3 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.7145471581406202 2.089708587948647 0.0366439850881397 1.0 0.2657143489685031 9 P04062,Q969V5 2 +Embryonic digit morphogenesis 0.7287555625633794 2.089497124301974 0.0366629965433982 1.0 0.2657143489685031 8 P42892,Q9NX62,Q9C0E8 3 +Regulation of anion transport 0.6672705020751722 2.0861369155849427 0.0369662226162794 1.0 0.2673132880140343 12 P14174,O75915,P08183,Q9HD26,Q15042,Q15041,Q13546,Q7L0J3 8 +Mitochondrial atp synthesis coupled proton transport 0.6663077252056928 2.0808114544495253 0.0374511673049331 1.0 0.2701953107929779 12 P00846,O75964,P56385,P24539,P36542 5 +Cotranslational protein targeting to membrane 0.6480638245140045 2.0769455511023187 0.0378065849133832 1.0 0.2715696088339807 13 Q99442,Q15629,P43307,P61619,Q15041 5 +Organic cation transport 0.776930351900299 2.072507661432628 0.038218122500029 1.0 0.274005387705821 7 O43808,Q9HC21,Q70HW3,Q86VD7,Q96QD8 5 +Aerobic respiration 0.379400213031693 2.0703722228676646 0.0384175009698897 1.0 0.274005387705821 97 O95298,Q7KZN9,O96000,Q9Y6M9,O14949,O43676,Q13423,P03886,P00403,P24539,Q9H3K2,O75964,Q9BSK2,P56385,P13073,P03915,Q15070,P00846,P21912,P36542,Q9UDW1 21 +Regulation of caveolin mediated endocytosis 0.9261576971214016 2.066740882184692 0.0387585767005456 1.0 0.274005387705821 2 Q96PU5 1 +Response to mitochondrial depolarisation 0.6948087407629604 2.062741960114516 0.0391371510081322 1.0 0.274005387705821 10 P04062,Q969V5 2 +Er nucleus signaling pathway 0.608509625277536 2.057842518550186 0.0396052530677173 1.0 0.2765104615472132 15 P57088,Q12770,Q96A33,Q9UKV5,Q15363,Q9UM00,P16615 7 +Ceramide catabolic process 0.7731513299595957 2.0548757412076357 0.0398910081158379 1.0 0.2770113782464623 7 P04062,Q13510 2 +Mitochondrial cytochrome c oxidase assembly 0.8245614035087758 2.0494065452037957 0.0404223777643655 1.0 0.279800672610667 6 Q9Y2R0,O43819,Q8N8Q8,Q15070,O75880 5 +Atp synthesis coupled proton transport 0.6420756489958064 2.042615504744168 0.0410905150404907 1.0 0.2815090006085393 13 P00846,O75964,P56385,P24539,P36542 5 +Amide transport 0.4544766358580401 2.041697940769656 0.0411815031672571 1.0 0.2815090006085393 40 P41440,P08183,Q9H2D1,P62820,Q92543,P50416,Q03519,P00367,P07602,P17302,Q8N5M9,Q9NZJ7,P40939,Q16836,O95563 15 +C4 dicarboxylate transport 0.703224127975551 2.0320388328840315 0.0421497248257041 1.0 0.2837802140977121 9 Q9H936,Q9UBX3,Q9UJS0,Q02978,Q8TDW0 5 +Electron transport chain 0.408034558594063 2.0302877209739663 0.0423273016201759 1.0 0.2837802140977121 76 O95298,Q7KZN9,O96000,Q9Y6M9,O14949,Q9Y6N1,O95139,O43676,P03886,Q12797,P00403,Q9P0J0,Q9H3K2,P20674,Q9H936,Q9Y375,O75208,P13073,P03915,O15460,P21912,P04062,P51970,O75306,O43819,O95169,Q9UDW1,P16435 28 +Tetrapyrrole catabolic process 0.9034302198413314 2.028169816046566 0.0425429193714244 1.0 0.2847339960412189 4 P09601 1 +Proton transporting two sector atpase complex assembly 0.8186090225563948 2.023160050999202 0.0430566489305372 1.0 0.2866899504922194 6 Q92544,Q8N511,Q9BUB7,Q15070,Q3ZAQ7 5 +Regulation of cellular extravasation 0.913642052565712 2.0117887871247695 0.0442422064365 1.0 0.2924775894351665 2 Q11206 1 +Cdp diacylglycerol metabolic process 0.6989379037067953 2.0101093772564105 0.0444196138114312 1.0 0.2927532999873553 9 Q9HCL2,O14735,O95674 3 +Regulation of cysteine type endopeptidase activity 0.4387099525301427 2.009102595058729 0.0445262545121689 1.0 0.2928596739865422 45 Q9BXK5,P51572,P51812,Q96A26,Q15392,Q969V5,Q9P0J0,O75340,Q9NZJ7,P16435,Q15041 11 +Early endosome to golgi transport 0.7625756397341773 2.005350888739116 0.0449255480623367 1.0 0.2948865588838167 7 Q9BVK6,O60499,O15260,P49257 4 +Endoplasmic reticulum calcium ion homeostasis 0.7114176084382569 2.0032707338671645 0.045148237001219 1.0 0.2954493325297166 8 Q96A33,P51572,P55061,P16615 4 +Intracellular transport 0.3289791959361995 1.99680643936185 0.0458462137960837 1.0 0.2962782127580997 550 O75431,Q99595,P43307,P24390,P07196,Q15904,P45880,Q8N4H5,Q96RQ1,Q9UNK0,Q6IQ22,Q13190,Q7Z3B4,P61019,O75298,P46379,P13473,O75844,Q7Z434,Q4J6C6,Q9NS69,Q3ZCQ8,P56589,Q8N8Q8,Q9Y282,Q9UBX3,Q15629,O75964,O14653,Q969V5,O60725,Q9Y5M8,P57105,Q9P2W9,Q9NZJ7,Q15070,P16615,P00846,O14925,Q10713,O95070,P07602,P36542,Q15005,Q969Q5,Q8NHH9,O60499,Q9BRK0,P40855,Q9Y371,Q8N2H4,Q9P0J0,P62072,Q14108,Q9H300,Q7Z4L5,Q96PC5,P52789,O94901,Q9Y3A6,Q9NR31,P10619,Q9UBV2,Q969X5,O95249,Q8WWC4,Q92544,P50402,Q8NBM4,Q9BVK6,Q9Y3B3,Q15041,O75503,Q00765,Q9BSR8,Q5SNT2,P51572,P12235,O15118,O75340,P24539,P11279,O14966,P49755,Q96JX3,P56385,P62820,Q9GZP9,Q03519,O43681,P23786,Q6NUK1,P61026,O75381,O96008,P56134,O43615,P49257,O15260,Q8NFH5,Q9Y512,Q96CS3,O60313,Q8TB36,Q96HR9,O14678,O15504,Q9H0U4,Q99442,Q12769,P61619,Q99623,Q15363,A0AVF1,O15400,Q9H1P3,P31751,Q12770,Q9UGP8,P05141,A4D1P6,Q53H12,P50416,O15498 124 +Folic acid transport 0.910200250312901 1.9966387295349692 0.0458644424250138 1.0 0.2962782127580997 2 Q9H2D1 1 +Folate transmembrane transport 0.910200250312901 1.9966387295349692 0.0458644424250138 1.0 0.2962782127580997 2 Q9H2D1 1 +Sphingoid metabolic process 0.8582543924588489 1.995039957166488 0.0460385220774146 1.0 0.2964789202836095 5 P04062,Q06136,Q13510 3 +Signal peptide processing 0.8118901394707072 1.993447191238112 0.0462125007302633 1.0 0.296619816042915 6 P67812,Q9H300,Q15005 3 +Body fluid secretion 0.6503314835934786 1.9919629073465677 0.0463751278417203 1.0 0.296619816042915 12 Q9UNS2,P00403,Q86UL3,Q13505,P52789 5 +Protein catabolic process in the vacuole 0.7595371764270908 1.9910728191709517 0.0464728821797768 1.0 0.296619816042915 7 Q8N511,O14773 2 +Lysosomal protein catabolic process 0.7595371764270908 1.9910728191709517 0.0464728821797768 1.0 0.296619816042915 7 Q8N511,O14773 2 +Negative regulation of neuron projection development 0.533782582889621 1.9860583897605943 0.047026840848251 1.0 0.2992701218976211 23 Q9NQC3,Q9NQX7,Q9NR77,Q96G23,P08670,O14966 6 +Mitochondrial calcium ion transmembrane transport 0.6938208140349855 1.9838578996815488 0.0472716833613364 1.0 0.2993760654975058 9 O95202,P21796,Q9BPX6,Q8WWC4 4 +Positive regulation of cysteine type endopeptidase activity 0.5041073781673467 1.983020505922693 0.0473651390679534 1.0 0.2993760654975058 28 Q9BXK5,P51572,Q96A26,Q969V5,Q9P0J0,Q9NZJ7 6 +Protein import into mitochondrial matrix 0.6910893024141006 1.9698132046306365 0.0488597826645997 1.0 0.3052321557966118 9 Q99595,O96008,O14925,Q3ZCQ8,O43615,Q96DA6,Q15388 7 +Chloride transport 0.6286735833167718 1.9652913737953 0.0493805234218311 1.0 0.3059857539771162 13 P08183,P51790,Q9UHG3,Q96S66,Q4KMQ2,Q9C0H2 6 +Toll like receptor signaling pathway 0.5925233714051451 1.9589314632550352 0.0501208137401256 1.0 0.3074710014465339 15 P41440,Q9NPR9,Q9NQC3,Q9UMX0 4 +I kappab kinase nf kappab signaling 0.4249899910902579 1.9569372159169776 0.0503548503748629 1.0 0.307650377354721 49 Q9Y3E0,O43657,P09601,Q8TB61,Q969V5,O60858,Q9P035,Q86UE4 8 +Vesicle mediated transport 0.3146961880061298 1.9540215365657776 0.0506986702761096 1.0 0.3086752530827672 349 O95197,P24390,Q15904,O15020,Q9UNK0,Q96RQ1,Q6IQ22,Q13190,P61019,P50897,O43760,P09601,Q4J6C6,Q9H4A6,Q9Y282,O14653,Q5VW38,Q92543,P57105,Q9P2W9,Q9Y6Y8,Q9Y3C0,P49841,P16615,Q9HD26,Q08380,O43731,Q92905,O95070,Q5JRA6,Q13636,Q8N5M9,Q9Y3E0,Q8NHH9,Q9NX40,O60499,Q8N2H4,Q14108,Q96PC5,Q96PU5,O14828,O15258,Q9Y3A6,Q9NR31,Q13432,Q969X5,O95249,Q12981,Q8WTV0,Q92544,Q9BVK6,Q08722,Q9Y3B3,Q4KMQ2,Q7L0J3,P41440,O75503,Q9BSR8,P51572,O15118,O75340,P98194,P11279,O14966,P49755,P62820,P61026,Q9UBG0,P49257,O15260,Q8TBA6,Q9BRK5,Q8NBU5,P48739,P51790,Q9H0U4,Q8IZ07,Q15363,O15400,P31751,Q12770,P27824,A4D1P6,O15498 84 +Negative regulation of protein secretion 0.6736253985626792 1.951303424190312 0.0510209619873303 1.0 0.3100541464619734 10 Q16850,P04035,Q8N5M9,P40939 4 +Long chain fatty acyl coa biosynthetic process 0.7508471581567332 1.9501168037435237 0.0511621988591244 1.0 0.3104067337310209 7 Q9NZ01,Q53GQ0 2 +Adp transport 0.8471656749138723 1.9479096062956416 0.0514257801554656 1.0 0.3113448542246712 5 P12236,O43808,Q86VD7,P12235 4 +Neutral amino acid transport 0.8008965349838608 1.94463387065256 0.0518190597520313 1.0 0.3126004403058742 6 Q96NB2,Q9H2J7,Q96QD8 3 +Pyrimidine containing compound transmembrane transport 0.8979974968710966 1.9427962869261872 0.0520407767267552 1.0 0.3131118290090794 2 Q9HC21 1 +Negative regulation of secretion 0.5431227459175183 1.9390119673067636 0.0524998809617704 1.0 0.3143193613178341 20 P04035,P09601,Q16850,P40939,Q8N5M9 5 +Establishment of protein localization to mitochondrial membrane 0.5475526958379449 1.9379338259158183 0.0526312964669284 1.0 0.3146253375688015 19 Q53H12,Q9Y512,Q9NS69,P62072,Q8N8Q8,Q9P0J0,Q9Y276,Q8WWC4,Q15070 9 +Mitochondrial electron transport cytochrome c to oxygen 0.7480718335040974 1.9369992049442468 0.0527454405534841 1.0 0.3146253375688015 7 Q7KZN9,P13073 2 +Mucopolysaccharide metabolic process 0.670611259516399 1.93533342130908 0.0529493936223015 1.0 0.3155510824341949 10 O43505,P15586,Q8NCH0,Q11206,Q9NX62 5 +Zinc ion transport 0.8939299123904989 1.9248053636735032 0.0542537127353097 1.0 0.322090226555822 2 Q8TAD4 1 +Retrograde transport endosome to golgi 0.4703189409598853 1.9208996931670408 0.0547443544670616 1.0 0.3235666320646783 32 O75503,O15498,Q9BVK6,O60499,O95249,Q13190,P49257,O15260,O14966 9 +Nuclear pore organization 0.6374083148063712 1.919435440280718 0.0549292493681488 1.0 0.3240675495995068 12 Q7Z3B4,Q9NQC3,Q9BTX1 3 +Chloride transmembrane transport 0.7435109315686037 1.915402837842213 0.0554411495232072 1.0 0.326492374626203 7 Q9UHG3,Q4KMQ2,P51790 3 +T cell apoptotic process 0.652118174720556 1.9113982813781785 0.0559534173986866 1.0 0.3280167730111413 11 P24390 1 +Plasma membrane phospholipid scrambling 0.8901752190237793 1.908179626840799 0.0563680038709799 1.0 0.3289954966056217 2 Q4KMQ2 1 +Nuclear envelope organization 0.4740180923417634 1.9026950505850095 0.0570803481505668 1.0 0.3295486291083573 31 O14657,P50402,Q9H6H4,Q86XL3,O75844,Q6NUK4,O94901 7 +Calcium ion transport 0.4122267801339563 1.8963905879013552 0.0579084155322298 1.0 0.3334370687941204 62 Q9BPX6,O95202,Q4KMQ2,Q96RD7,O75844,P21796,Q9UM00,P20020,P98194,Q9Y4W6,P23634,P61619,O75323,Q9UMX0,P16615,Q96HE7,Q96BY9,P78417,P55061,Q8WWC4,Q00535 21 +Long chain fatty acyl coa metabolic process 0.6763242481077508 1.8935163350517292 0.0582892379874302 1.0 0.3343339743702838 9 Q9NZ01,Q53GQ0 2 +O glycan processing 0.737777927038391 1.888187619987437 0.0590007672223569 1.0 0.3361381738231461 7 Q11206,Q8N4A0,Q10472 3 +Lipid modification 0.4178222313234002 1.88420470167318 0.0595372918330969 1.0 0.3363571585608915 50 P31751,O43808,Q9NTJ5,P35610,P04062,O14678,Q10713,O15254,Q53H12,Q15067,Q11206,A1L0T0,Q709F0,P16435,P23786,Q96N66,P40939,Q16836 18 +Collagen metabolic process 0.6742267597139784 1.8826261863713485 0.0597510450262175 1.0 0.3363571585608915 9 Q92791,Q32P28,P08670 3 +Glycosylceramide biosynthetic process 0.8842302878598252 1.8818195634454695 0.0598605186395155 1.0 0.3363571585608915 2 Q16739 1 +Glycosphingolipid biosynthetic process 0.8842302878598252 1.8818195634454695 0.0598605186395155 1.0 0.3363571585608915 2 Q16739 1 +Oligosaccharide metabolic process 0.67310780818044 1.8768113764960792 0.0605439506767115 1.0 0.339148885554462 9 P15291,Q10469,Q11206,P17900,O75352 5 +Nervous system process 0.3547365831903948 1.874289496380969 0.0608905344552368 1.0 0.3393731739292028 109 Q9Y5J9,P61160,Q00169,P07196,Q9Y6M9,Q11206,P10253,Q9BRK0,P50897,Q8NBU5,O60313,O75844,O75569,P62072,Q14108,Q96HR9,P17900,Q9H5K3,Q8N0X7,P23634,Q9UQB8,Q9UKV5,Q13641,P18887,Q9BPW8,P49841,O75915,O14773,P78417,P04062,Q9H0U3,P53611,Q92542,Q13432,Q96DA6,Q08209,Q9H6K4,O00264,P04035,P53634,Q9NWW5,O75746,O76024,Q00535 44 +Golgi organization 0.412467779559093 1.8742508750532607 0.0608958549640383 1.0 0.3393731739292028 59 Q8NHH9,Q8TBA6,Q9BVK6,Q13190,Q9Y3B3,Q96JB2,P61019,Q9BTU6,Q7RTS9,Q9BSR8,Q9H4A6,Q14789,O15027,P49755,Q14155,O14966,P62820,Q15363,Q9P2W9,Q9Y6Y8,Q9Y3A6,Q7Z3D4,P49257,O15260 24 +Viral protein processing 0.6443380879159065 1.86879431506877 0.0616514361008735 1.0 0.3413242895165556 11 Q16706,P27824,Q10469,Q11206,Q10472 5 +Divalent inorganic cation homeostasis 0.4130011001200696 1.866183125673895 0.0620157491040798 1.0 0.3427548490193036 57 Q9BPX6,O95202,Q16891,Q7L0J3,P51572,Q96A33,Q9HD20,Q9UM00,P20020,P98194,Q9Y4W6,P23634,Q15043,Q8TAD4,P16615,Q96HE7,P78417,P55061,Q8WWC4,Q96TC7,Q00535 21 +Iron ion homeostasis 0.5411120439870045 1.864980011609158 0.0621842060209232 1.0 0.343392646217931 18 Q8N511,Q658P3,Q9Y487,P09601,P30519,Q15904,Q15043 7 +Proteoglycan biosynthetic process 0.7318765072544616 1.8600934225259995 0.0628723096173389 1.0 0.345045045939074 7 Q8NCH0,Q8WVQ1,Q7LGA3 3 +Secondary alcohol metabolic process 0.4312040526246371 1.8590211320610872 0.0630241430970877 1.0 0.345045045939074 42 Q15800,Q12770,Q9UBM7,O75845,P04062,P35610,P37268,Q14534,Q15392,Q16850,Q9NWW5,O15118,P04035,Q14739,P16435,Q8WTV0 16 +Glycosylceramide metabolic process 0.8260874996613843 1.8577395787146391 0.0632060051076308 1.0 0.345045045939074 5 P04062,Q16739 2 +Export from cell 0.3478449763242405 1.8553258734287268 0.0635497056179505 1.0 0.345045045939074 140 P14174,Q9BRT2,Q6IQ22,P40939,Q9BRK5,Q4KMQ2,Q7L0J3,P50897,O43760,P08183,P09601,Q16850,Q4J6C6,P17302,Q9H4A6,P20020,Q16836,P11279,P49755,Q96PC5,Q658P3,Q92543,P62820,Q96KC8,P00367,Q9Y3C0,O95563,P49841,P16615,Q32P28,P61026,P27824,Q92905,Q9UBV2,P05023,P50416,Q5JRA6,Q13636,P04035,O15498,Q8N5M9,Q00535 42 +Mannosylation 0.7279531201904484 1.8413715258944463 0.0655671325543372 1.0 0.3512250023357842 7 O43505,Q9BT22,Q9BV10,O75340,Q2TAA5 5 +Maintenance of protein localization in organelle 0.5907292126341572 1.840858042371159 0.065642364412815 1.0 0.3512250023357842 14 O43731,P24390,O43292,Q9UH99,O15258,P52789,O94901 7 +Mitochondrial calcium ion homeostasis 0.6528648116860373 1.840738137958817 0.0656599421770218 1.0 0.3512250023357842 10 P51572,Q9BPX6,O95202,Q8WWC4,Q16891,Q9Y4W6 6 +Carbohydrate transport 0.5379192239011987 1.8387405313682696 0.0659533588445442 1.0 0.3524774058149383 17 Q96AA3,P52789,O75298 3 +Membrane fusion 0.4289187627911245 1.836238399750119 0.0663224057658826 1.0 0.3535535869496614 42 P31751,Q9BSR8,O14653,Q8IWA4,O60499,Q9UNK0,O95249,Q9P2W9,Q12981,O15400,O15498 11 +Response to oxygen levels 0.4052273432336425 1.835326329331662 0.0664573521418998 1.0 0.3535535869496614 64 Q92544,Q9Y487,Q15904,Q96A26,Q8N511,P09601,P30519,Q15118,Q99623,P03915,P18887,Q8IXJ6,P52789,Q9UMX0,Q12770,P00846,P55061,O75306,Q9Y4P3 19 +Regulation of mitophagy 0.6781122287580577 1.835284752125069 0.0664635091288861 1.0 0.3535535869496614 8 P27544,P21796,P12235 3 +Protein insertion into mitochondrial inner membrane 0.726418050767804 1.8340368045149145 0.0666485310451101 1.0 0.3537753146597259 7 Q9Y5J6,Q9Y5J9,Q9P0J0,P62072,Q53H12,O94826 6 +Regulation of retrograde protein transport er to cytosol 0.8560138577758467 1.8327279200840232 0.0668430430429363 1.0 0.3537753146597259 4 P51572,Q8NBM4 2 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.6775701496219543 1.8325254249456633 0.0668731773493029 1.0 0.3537753146597259 8 Q8N4V1,Q9P0I2,Q9NPA0,Q5J8M3,Q15006 5 +Epithelial cell differentiation involved in prostate gland development 0.9552452491738608 1.8299437673992232 0.0672583478746835 1.0 0.3547632328814213 3 Q9NZJ7 1 +Sphingosine biosynthetic process 0.8551560464638273 1.829161556173188 0.0673754096805001 1.0 0.3548036220115517 4 P04062,Q13510 2 +Sulfur compound transport 0.6193957657356384 1.8173732238236928 0.0691599848310993 1.0 0.3611738884052921 12 Q9UBX3,P10620,Q02978,Q8TB61,Q8TDW0,P17302,Q9HC21,Q70HW3,P33527 9 +Glycolipid transport 0.9505477308294188 1.811279253503081 0.0700976354758369 1.0 0.3628737298299853 3 P07602,Q9NZJ7 2 +Negative regulation of cell volume 0.8679599499374204 1.8094608960028415 0.0703794299407951 1.0 0.3628737298299853 2 Q4KMQ2 1 +Positive regulation of erbb signaling pathway 0.814289565767432 1.806946067288541 0.070770688768522 1.0 0.3638029370213457 5 Q9NQC3 1 +Multicellular organism aging 0.659450714963006 1.8055494821423288 0.070988739701731 1.0 0.3640369813429989 9 O75844 1 +Apoptotic mitochondrial changes 0.4572058884746161 1.8052139461188192 0.0710412094308108 1.0 0.3640369813429989 32 O60313,Q96A26,Q969V5,P52789,P12235,Q3ZCQ8,P05141,P45880,Q9H3K2,Q9H300 10 +Release of cytochrome c from mitochondria 0.5841400260848524 1.800706839576771 0.0717490990135267 1.0 0.3650630257983846 14 O60313,Q96A26,Q9H300,Q9H3K2 4 +Cellular respiration 0.3492830140299461 1.7922733194843743 0.0730891949387797 1.0 0.3715893712834112 114 O95298,Q7KZN9,O96000,Q9Y6M9,O14949,O43676,Q13423,P03886,P00403,P24539,Q9H3K2,O75964,Q9BSK2,P56385,P13073,P03915,Q15070,P00846,P21912,P04062,P36542,Q9UDW1 22 +Glial cell migration 0.6139633295587401 1.7863726565414175 0.0740389398656313 1.0 0.3737795488594856 12 Q96N66,Q9NQC3,Q96G23 3 +Prostate gland growth 0.9442867070613272 1.7863675355063182 0.0740397684854543 1.0 0.3737795488594856 3 Q9NZJ7 1 +Mammary gland development 0.5291891161451338 1.7829731470881058 0.0745906746336266 1.0 0.375389460520087 18 P31751,Q9UNS2,Q9NQC3,P00403,Q99623,Q86UL3,Q13505,P52789 8 +Vascular transport 0.596836397326193 1.7789109534926624 0.0752543620289538 1.0 0.3766109740251765 13 P41440,Q8WWI5,P23634,P08183,P14672,P30825,Q96QD8 7 +Calcium ion transmembrane transport 0.413116584452532 1.772734630118415 0.0762726899076837 1.0 0.379428784844373 46 Q9UMX0,Q96HE7,P23634,P61619,P78417,Q00535,Q96RD7,Q9BPX6,O75323,O95202,P21796,Q9UM00,Q8WWC4,P20020,Q4KMQ2,P98194,Q9Y4W6,P16615 18 +Regulation of blood pressure 0.5237524938733451 1.772188534130297 0.0763632662817024 1.0 0.379587603206742 19 Q6P179,P42892,Q9UIQ6,Q93063,P09601,P05023,P42785,Q9NZ08,P20020 9 +Atp metabolic process 0.3476700762009426 1.7699755102104011 0.0767312204793668 1.0 0.3808316402932993 117 O95298,Q7KZN9,O96000,Q9Y6M9,Q9BRR6,O14949,O43676,P03886,P00403,P24539,Q9H3K2,O75964,Q9BSK2,P56385,P13073,P03915,P52789,P00846,P36542,Q9UDW1 20 +Neutral lipid biosynthetic process 0.711860773070883 1.7642163892329388 0.0776955544401616 1.0 0.3844385537742554 7 Q9HCL2,Q8WTV0,Q92604 3 +Regulation of leukocyte degranulation 0.83934293938361 1.7632344174937993 0.0778609611934815 1.0 0.3849626744417206 4 P09601 1 +Bone morphogenesis 0.6513004128372072 1.7627685329867695 0.0779395366450772 1.0 0.3850570085243816 9 Q7Z3C6,O75844,Q9NX62,P16435,Q92896 5 +Carbohydrate phosphorylation 0.711271660570315 1.7613809052901297 0.0781739546888558 1.0 0.3859205451916664 7 Q9H5K3 1 +Regulation of mammary gland epithelial cell proliferation 0.8570087609512087 1.7605921986869717 0.0783074499895255 1.0 0.3862849209849157 2 Q9NQC3 1 +Negative regulation of mitochondrion organization 0.5263052311528249 1.7593305572843383 0.0785213792952008 1.0 0.3867506596640335 17 O60313,P05141,Q969V5,Q99536,Q9H3K2,Q9H300 6 +Positive regulation of autophagy 0.4518482871145239 1.7575554210874988 0.0788231841035711 1.0 0.3868321780244932 32 P09601,Q9Y371,Q9BXS4,O60858,P27544,P21796,Q86UE4 7 +Alcohol metabolic process 0.3821088361651371 1.7561869761667734 0.0790564877679518 1.0 0.3876163551774123 79 P14324,Q9H3H5,Q15392,Q14739,Q15800,Q8NBN7,P35610,Q16850,O15269,O15118,P51648,O75845,Q14534,P37268,Q9Y394,Q12770,Q9UBM7,P04062,Q10713,P16435,Q9NX62,Q13510,P04035,Q9NWW5,Q8WTV0 25 +Mitochondrial electron transport ubiquinol to cytochrome c 0.8369693427146812 1.7533090873324428 0.079548966510861 1.0 0.3892150801094986 4 O14949 1 +Negative regulation of autophagy 0.5169026532534866 1.7532274592303188 0.0795629714129892 1.0 0.3892150801094986 20 P09601,P10619,O15118,Q07820 4 +Positive regulation of glycoprotein metabolic process 0.7092215427674445 1.7515074346156565 0.0798585417834079 1.0 0.3903659232796193 7 P35610,P62820,Q9H0U4 3 +Regulation of srebp signaling pathway 0.8548185231539422 1.7508035682109986 0.0799797517698936 1.0 0.3903847199773446 2 Q9UKV5 1 +Calcium import into the mitochondrion 0.7577538241433809 1.7507845717899195 0.0799830251375091 1.0 0.3903847199773446 6 Q8WWC4,P21796,Q9BPX6 3 +Organic hydroxy compound biosynthetic process 0.4049163149808059 1.7485526058597047 0.0803683847855556 1.0 0.3913801251558435 51 P14324,Q15800,Q86SQ9,Q12770,O75845,Q9UBM7,P04062,P37268,Q14534,Q15392,Q9UHQ9,Q16850,O15269,Q13510,P04035,Q14739,P16435,Q9H1P3 18 +L glutamate transmembrane transport 0.7085290814397422 1.7481704210384257 0.0804345218277353 1.0 0.3914076881722581 7 Q9H936,O60831,O75915,Q9UJS0,Q15041 5 +Phosphatidylglycerol biosynthetic process 0.8353501032479498 1.746533840489817 0.0807182320731831 1.0 0.3917048205532648 4 Q9HCL2 1 +Mitophagy 0.524072375576796 1.7439871207461433 0.0811613356554277 1.0 0.3917048205532648 17 Q99623,P21796,P12235,P27544 4 +Positive regulation of protein kinase b signaling 0.5743563896076863 1.74077611059615 0.0817228310262099 1.0 0.3934520227547173 14 Q9NQC3,Q86UE4 2 +Cellular response to oxygen levels 0.4288673927067407 1.737701758612339 0.0822633786966162 1.0 0.3938602174991802 37 Q96HE7,Q8N511,P09601,Q9Y487,Q99623,Q15904,Q96A26,P55061,O75306,Q15118,Q9Y4P3,Q8IXJ6,Q9UMX0 13 +Oligosaccharide biosynthetic process 0.8321853475266114 1.7332818383804582 0.083045587190742 1.0 0.3963650739664326 4 Q11206,P15291,Q10469 3 +Gpi anchor metabolic process 0.7051060616461563 1.7316592934649968 0.0833342423823233 1.0 0.396859831396156 7 Q5H8A4,O43292,Q9H490 3 +Response to light intensity 0.8498122653316784 1.7284118541187814 0.0839144117366386 1.0 0.396859831396156 2 Q8NBN7 1 +Very long chain fatty acid metabolic process 0.6038365534093352 1.7283164297062252 0.0839315090576822 1.0 0.396859831396156 12 P28288,O14975,Q15067,Q9P035,Q6Y1H2,O14678,Q9NZ01,P33121 8 +Positive regulation of alcohol biosynthetic process 0.8491864831038791 1.7256111996278751 0.084417383133764 1.0 0.3982137781645194 2 P16435 1 +Positive regulation of cholesterol biosynthetic process 0.8491864831038791 1.7256111996278751 0.084417383133764 1.0 0.3982137781645194 2 P16435 1 +Positive regulation of steroid biosynthetic process 0.8491864831038791 1.7256111996278751 0.084417383133764 1.0 0.3982137781645194 2 P16435 1 +Negative regulation of nervous system development 0.5204656633570607 1.7191514504997558 0.0855867983802562 1.0 0.4012223105132385 17 Q8N0X7,Q9NQC3,Q96G23 3 +Hormone biosynthetic process 0.7503700899502955 1.717256728068313 0.0859322746391981 1.0 0.401738310437242 6 P16435,Q9UBM7,P05023,Q53GQ0 4 +Regulation of macroautophagy 0.4000182331249651 1.7159903506715792 0.0861638085277045 1.0 0.4020563581768593 56 Q93050,P09601,Q9Y487,Q9Y371,P04062,O60858,P12235,O15118,P27544,P21796 10 +Maintenance of protein localization in endoplasmic reticulum 0.8271075480554609 1.7119920049451482 0.0868981418517553 1.0 0.4037801953510662 4 P24390,O15258 2 +Protein retention in er lumen 0.8271075480554609 1.7119920049451482 0.0868981418517553 1.0 0.4037801953510662 4 P24390,O15258 2 +Regulation of steroid hormone biosynthetic process 0.8460575719649555 1.7116024521372049 0.0869699561228927 1.0 0.4037801953510662 2 P16435 1 +Regulation of hormone biosynthetic process 0.8460575719649555 1.7116024521372049 0.0869699561228927 1.0 0.4037801953510662 2 P16435 1 +Positive regulation of striated muscle contraction 0.8460575719649557 1.7116024521372049 0.0869699561228927 1.0 0.4037801953510662 2 P78417 1 +Cell adhesion molecule production 0.8261877943552718 1.7081321900303568 0.0876118172003042 1.0 0.4037801953510662 4 Q9H4A6 1 +Leukocyte adhesion to vascular endothelial cell 0.826159275789905 1.708012492564612 0.087634024488399 1.0 0.4037801953510662 4 Q9H4A6 1 +Lipoprotein biosynthetic process 0.5683401002268059 1.7037386270418968 0.0884299283165246 1.0 0.4043794723862535 14 Q9H490,P04062,O43292,Q16739,Q5H8A4 5 +Inorganic ion import across plasma membrane 0.6985639031771768 1.7000323005022644 0.0891248500190204 1.0 0.4043794723862535 7 Q9BXP2,P23634,P05023,Q15043 4 +Lymphocyte apoptotic process 0.5514628918165785 1.6998412285250897 0.0891607941691838 1.0 0.4043794723862535 15 P24390 1 +Pirna metabolic process 0.8432415519399232 1.698986952469262 0.0893216420327125 1.0 0.4043794723862535 2 Q8N2A8 1 +Estrogen biosynthetic process 0.8429286608260467 1.6975847941806066 0.0895861547448606 1.0 0.4043794723862535 2 Q53GQ0 1 +Triglyceride biosynthetic process 0.7458072079177973 1.6964888473581747 0.089793340488371 1.0 0.4043794723862535 6 Q9HCL2,Q8WTV0,Q92604 3 +Regulation of triglyceride metabolic process 0.8231260585342759 1.6952756800361206 0.0900231361017476 1.0 0.4043794723862535 4 Q96N66,Q8NCG7 2 +Positive regulation of fatty acid beta oxidation 0.8423028785982472 1.6947802195723385 0.0901171212104106 1.0 0.4043794723862535 2 P31751 1 +Positive regulation of fatty acid oxidation 0.8423028785982472 1.6947802195723385 0.0901171212104106 1.0 0.4043794723862535 2 P31751 1 +Regulation of fatty acid beta oxidation 0.8423028785982472 1.6947802195723385 0.0901171212104106 1.0 0.4043794723862535 2 P31751 1 +Golgi to plasma membrane protein transport 0.516876275858334 1.694372253816539 0.0901945685013734 1.0 0.4043794723862535 17 P61026,Q8N2H4,Q4J6C6,Q9H4A6,Q13636,P98194,Q9HD26 7 +Positive regulation of toll like receptor signaling pathway 0.7882881847607008 1.6942241704273904 0.0902226935612242 1.0 0.4043794723862535 5 Q9NQC3 1 +Aminoglycan biosynthetic process 0.6379188800641961 1.6921270741687051 0.090621747294769 1.0 0.4043794723862535 9 O43505,Q8NCH0,Q11206,Q7LGA3 4 +Negative regulation of cell projection organization 0.4444037525069427 1.690959512077958 0.0908445357227376 1.0 0.4043794723862535 32 Q9NQC3,Q9NQX7,Q9NR77,Q96G23,P08670,O14966 6 +Lipid droplet organization 0.6376412947073352 1.690656491240685 0.0909024286011093 1.0 0.4043794723862535 9 Q8N0X7,Q14534,O95674 3 +Cerebral cortex radially oriented cell migration 0.6494197022805286 1.688156564457081 0.0913811786515546 1.0 0.4043794723862535 8 Q96N66,Q9NQC3 2 +Telencephalon glial cell migration 0.6494197022805286 1.688156564457081 0.0913811786515546 1.0 0.4043794723862535 8 Q96N66,Q9NQC3 2 +Vesicle targeting rough er to cis golgi 0.6115556711992622 1.6871436240832012 0.0915757385248636 1.0 0.4043794723862535 11 P49755,Q9UBV8,Q9NR31,Q9HCU5,Q15363,O75340,Q9Y6B6,O15027 8 +Regulation of anion transmembrane transport 0.6947762686497402 1.681679831416265 0.0926309410069079 1.0 0.4075942315087401 7 Q13546,Q15041,P08183,Q9HD26 4 +Prostate gland development 0.7423843868317476 1.6808858416488013 0.0927850905639795 1.0 0.4075942315087401 6 Q9NZJ7 1 +Selective autophagy 0.4376348119867028 1.679642088209521 0.0930269736086075 1.0 0.4075942315087401 33 Q99623,Q86VR2,O15269,P12235,P27544,P21796,Q5T8D3,Q9Y6I9,Q9UMX0 9 +Regulation of mitochondrial gene expression 0.5799861944867524 1.6787668749407298 0.0931974867641551 1.0 0.4078256486393593 13 Q9Y2R0,Q567V2 2 +Cellular extravasation 0.7406380749036517 1.672917375720553 0.094343562685756 1.0 0.4112007139405221 6 Q11206,Q9H4A6 2 +Positive regulation of mitochondrial translation 0.6340375076450895 1.6715455476075365 0.0946139699681951 1.0 0.4115142585268949 9 Q9Y2R0 1 +Post translational protein modification 0.6079187479864978 1.6667838804199269 0.0955573866458028 1.0 0.4136771948974153 11 O75718,Q92905,P46977,O60725,Q8TCJ2,Q32P28 6 +Alditol phosphate metabolic process 0.9136825804470696 1.664064705603549 0.0960994993346497 1.0 0.4157459623622015 3 Q9HCL2 1 +Maintenance of protein location in cell 0.4951785754953212 1.6605343557518262 0.096807002392335 1.0 0.4179685920501618 22 P24390,Q9H4A6,O15258,P52789,O94901 5 +Myelin assembly 0.7786994410155463 1.6523987409103085 0.0984532920465826 1.0 0.422376522813678 5 Q9NR77,O15228 2 +Mitotic nuclear membrane organization 0.7358641947940897 1.6511072631390056 0.0987166745018717 1.0 0.422376522813678 6 Q9H6H4,Q86XL3,Q6NUK4 3 +Lipid droplet formation 0.8125872654490404 1.6509338850977124 0.0987520758039601 1.0 0.422376522813678 4 O95674 1 +Positive regulation of lipid catabolic process 0.812527198562759 1.6506807714163445 0.0988037761748681 1.0 0.422376522813678 4 P31751,Q8NCG7 2 +Vesicle cargo loading 0.5434251361610284 1.648296360018139 0.0992918713268644 1.0 0.4236655055317579 15 P49755,Q12770,Q96PC5,Q9NR31,P62820,Q15363 6 +Golgi vesicle budding 0.7352357857659821 1.648233399556675 0.0993047855209636 1.0 0.4236655055317579 6 P49755,Q9BVK6,Q9H4A6 3 +Prenylation 0.8116014744132878 1.646779358494376 0.0996034055808141 1.0 0.4245187627802113 4 P53611,P49356 2 +Regulation of organic acid transport 0.6040026068737921 1.6448162022633643 0.1000077198759541 1.0 0.4255172182584741 11 P31751,P14174,O75915,Q9Y3D6,Q15042,Q15041,Q7L0J3,P33121 8 +Positive regulation of mitochondrion organization 0.4682121162339377 1.643108195043153 0.1003605496099599 1.0 0.4255172182584741 27 Q96A26,Q969V5,P27544,P12235,P21796 5 +Vesicle targeting to from or within golgi 0.573353571656277 1.6390725126317678 0.1011981588667527 1.0 0.4259300301468592 13 P49755,Q9UBV8,Q9NR31,Q9HCU5,Q15363,Q9BVK6,O75340,Q9Y6B6,O15027 9 +Cellular iron ion homeostasis 0.5576135792781068 1.6373628840493857 0.1015546686426864 1.0 0.42623982844064 14 Q8N511,P09601,Q9Y487,Q15904,Q15043 5 +Negative regulation of cell growth 0.4433772137130576 1.6346174713146868 0.102129262780612 1.0 0.4278191512725704 31 P50897,Q8N0X7,Q9NQC3,Q969V5,Q9P0J0 5 +Protein insertion into er membrane 0.5407029426078301 1.630780121640739 0.1029367233371869 1.0 0.430168981420848 15 Q15629,P61619,Q8N4V1,Q96A33,Q9NPA0,O43681 6 +Response to increased oxygen levels 0.626105612043107 1.629360246007702 0.103236779284662 1.0 0.4307855806127225 9 Q9Y487,Q8N511,P00846 3 +Mitochondrial genome maintenance 0.613089129595471 1.6252866927972296 0.1041014855504571 1.0 0.4321647302646304 10 P39210,Q9BSK2,O60313,P12235,P51530 5 +Iron ion transport 0.6126998439899562 1.6231555080941702 0.1045561661386669 1.0 0.4331731751973097 10 Q8N4V1,Q658P3,O15173,O75027,Q15043 5 +Chemokine production 0.6366841565702128 1.6221701539621185 0.104766920329772 1.0 0.4331731751973097 8 P09601,P14174,Q969V5 3 +Positive regulation of protein exit from endoplasmic reticulum 0.8057638701570375 1.6221541728377904 0.1047703412579164 1.0 0.4331731751973097 4 Q9NR31,Q92544 2 +Vesicle budding from membrane 0.4152191697732259 1.6219689630247596 0.1048099938409388 1.0 0.4331731751973097 38 P49755,Q12770,Q9UBV8,Q5JRA6,Q9NR31,P62820,O95486,P14672,Q9HCU5,Q9BVK6,O75340,Q15363,Q9Y6B6,Q9H4A6,P55735,O15027 16 +Negative regulation of protein localization 0.3987465261881112 1.6213305025017517 0.1049467766856275 1.0 0.4331731751973097 46 Q8IZ07,P04035,Q8NBM4,Q9BXS4,Q10713,Q9GZP9,Q16850,Q96PU5,Q8NFG4,P40939,P49257,Q16836,Q8N5M9,P49841,Q9HD26 15 +Leukocyte tethering or rolling 0.9019796315836832 1.6170866312666456 0.1058595821927226 1.0 0.4352752324976498 3 Q9H4A6 1 +Embryonic heart tube morphogenesis 0.8241551939924892 1.6133092075747224 0.1066773471341968 1.0 0.4375775974151878 2 Q15363 1 +Positive regulation of anion transport 0.6802126509851265 1.610836137391637 0.1072154423636695 1.0 0.4391761664415628 7 Q15041,P08183 2 +Serine transport 0.8023684004363689 1.6078130047849222 0.1078761393548268 1.0 0.4405684414317215 4 Q96NB2,Q96QD8 2 +Positive regulation of erad pathway 0.7684899430399068 1.60772371886806 0.1078957014322123 1.0 0.4405684414317215 5 P51572,Q4ZIN3,Q9UMX0 3 +Regulation of hormone metabolic process 0.7683500237070316 1.6071104739074031 0.1080301360915689 1.0 0.4407656065203034 5 P16435,O75844 2 +Negative regulation of hormone secretion 0.6330322535370743 1.6031745202727834 0.1088961291780514 1.0 0.4429765858204583 8 P17302,Q08209,P40939,Q16836,Q8N5M9 5 +Lipid catabolic process 0.3698990072773515 1.5994432280431574 0.1097221536452774 1.0 0.4449189503316905 79 Q15067,Q8NCG7,Q8N2K0,P40939,Q6PIU2,O95470,Q9H6V9,P50897,P35610,P17900,O14678,Q16836,Q8N2A8,O15254,Q709F0,P23786,Q8IXJ6,P11802,P31751,O43808,Q99735,P04062,A1L0T0,Q13510,Q8NBQ5,Q8WTV0 26 +Reflex 0.820713391739673 1.5978306698716918 0.1100806669931715 1.0 0.4449189503316905 2 P17302 1 +Keratan sulfate metabolic process 0.7997628111164913 1.5967993406899736 0.1103104429698995 1.0 0.4449189503316905 4 O43505,Q11206 2 +Positive regulation of lipid metabolic process 0.4985146259573514 1.593257776522087 0.1111023746826453 1.0 0.4467051779127967 19 P31751,Q12770,Q8WTV0,Q8NCG7,P16435,Q92604 6 +Ceramide transport 0.7230356775475896 1.592309425051022 0.1113151962471086 1.0 0.4467051779127967 6 P07602,Q9NZJ7 2 +Golgi ribbon formation 0.7223360701858333 1.589095163778311 0.1120389094942635 1.0 0.4478788278238874 6 Q9H4A6 1 +Peptidyl glutamic acid modification 0.7641317109338566 1.5886101380162736 0.1121484379402586 1.0 0.4479892307597155 5 Q8N0U8 1 +Fatty acid elongation 0.8948356807511666 1.5883599583387944 0.112204966480454 1.0 0.4479892307597155 3 Q9P035,Q9NZ01 2 +Columnar cuboidal epithelial cell maturation 0.8182102628285344 1.5865688167050505 0.1126103346600142 1.0 0.4482251450920124 2 Q86UL3 1 +Manganese ion transmembrane transport 0.8942097026604067 1.585841165136282 0.1127753449546169 1.0 0.4483304868220398 3 Q9HD20,P98194 2 +Manganese ion transport 0.8942097026604067 1.585841165136282 0.1127753449546169 1.0 0.4483304868220398 3 Q9HD20,P98194 2 +Diol biosynthetic process 0.6295661477731687 1.5851154895241215 0.1129400969058842 1.0 0.4484345442790692 8 P04062,Q13510 2 +Diol metabolic process 0.6295661477731687 1.5851154895241215 0.1129400969058842 1.0 0.4484345442790692 8 P04062,Q13510 2 +Respiratory chain complex iii assembly 0.721223453208195 1.5839817790591917 0.1131978656057852 1.0 0.4486323246788991 6 Q69YU5,Q9Y276,Q6DKK2,Q9BSK2 4 +Pyramidal neuron differentiation 0.8931678769852089 1.581648523276164 0.1137298302295257 1.0 0.4504647865639478 3 O14949 1 +Regulation of bone mineralization 0.7623341875472003 1.5807196671920984 0.1139421494590413 1.0 0.4506662019055897 5 P17302,Q4KMQ2,O75844 3 +Organelle disassembly 0.3883508613048687 1.5804497767413148 0.1140038998779278 1.0 0.4506662019055897 55 Q7Z3C6,P04062,Q99623,Q86VR2,Q969V5,P05141,P52789,P12235,P27544,Q9BWH2,P21796,Q9Y6I9,Q9H300 13 +Negative regulation of establishment of protein localization 0.4551000475802456 1.580208111047237 0.1140592148827805 1.0 0.4506662019055897 28 P04035,Q8NBM4,Q9GZP9,Q16850,P40939,Q16836,Q8N5M9 7 +Negative regulation of growth 0.421246809469928 1.579472113138528 0.1142278080584895 1.0 0.4510569699539623 34 P50897,Q8N0X7,Q9NQC3,Q969V5,Q9P0J0 5 +Regulation of glucose import 0.627943292433591 1.5766502514088805 0.1148760232508718 1.0 0.4530637553197091 8 P31751,P52789,O75298 3 +Phosphatidylglycerol acyl chain remodeling 0.8917057902973397 1.5757634249599315 0.1150803343851696 1.0 0.4533681335769261 3 Q8NF37,Q96JX3 2 +Regulation of biomineralization 0.7193065293963206 1.5751673671519164 0.1152178174463203 1.0 0.4533681335769261 6 Q4KMQ2,P17302,O75844 3 +T cell differentiation in thymus 0.6039295715295918 1.5750312631274883 0.1152492284793347 1.0 0.4533681335769261 10 O96005 1 +Heme transport 0.8153942428035255 1.5738947391918168 0.1155117863611494 1.0 0.4533681335769261 2 O15173 1 +Iron coordination entity transport 0.8153942428035255 1.5738947391918168 0.1155117863611494 1.0 0.4533681335769261 2 O15173 1 +Regulation of amyloid beta clearance 0.793627809730004 1.5708382773595415 0.116220218493749 1.0 0.4535754244114778 4 P04035 1 +Nuclear membrane reassembly 0.6027320595926305 1.56844407227566 0.1167775325054392 1.0 0.4547437968563192 10 Q9H6H4,Q86XL3,Q6NUK4 3 +Regulation of mitochondrial fusion 0.7177634391995026 1.5680677446063918 0.1168653232064063 1.0 0.4548120094960081 6 Q8N2A8,Q969V5,Q9Y6C9 3 +Positive regulation of peptidase activity 0.4059465542573378 1.565227097687626 0.1175296699110592 1.0 0.455923958834893 40 Q9BXK5,O75915,Q9Y3D6,P51572,Q96A26,Q969V5,O95831,Q9P0J0,O75340,Q9NZJ7,O00487,Q12797,Q9NR28 13 +Positive regulation of anion transmembrane transport 0.792183633918075 1.5647213347315228 0.1176482637583529 1.0 0.455923958834893 4 Q15041 1 +Positive regulation of pattern recognition receptor signaling pathway 0.6139296068678574 1.564283998287231 0.1177508883056386 1.0 0.455923958834893 9 Q9NQC3 1 +Negative regulation of bmp signaling pathway 0.7906341105288107 1.5581558174259351 0.1191963156850683 1.0 0.458016199435348 4 Q8N0X7 1 +Very long chain fatty acid catabolic process 0.756737484859509 1.5561259283471642 0.1196781505601269 1.0 0.4588150930806793 5 Q15067,O14678,O14975 3 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.8113266583229015 1.5555799046689436 0.1198080202883726 1.0 0.4588150930806793 2 Q9UIQ6 1 +Protein targeting to membrane 0.4115442400032687 1.5547473589493912 0.1200062506637211 1.0 0.4592523018319417 36 P40855,Q99442,Q15629,P31751,Q9UGP8,P43307,P61619,Q00535,O60725,O43681,P56589,Q15041,P46379 13 +Peptide catabolic process 0.5878819853626694 1.553909414050595 0.1202060258503259 1.0 0.4592523018319417 11 P42892,Q6P179,Q9UIQ6,O14773,Q9NZ08,P09960 6 +Insulin processing 0.8094493116395719 1.547123997325963 0.1218333483461373 1.0 0.4611142868398836 2 Q8TAD4 1 +Peripheral nervous system development 0.5720430912046589 1.543865692075497 0.1226208729249929 1.0 0.461128581970107 12 P31751,Q9NR77,Q16880,P51648,Q8IXJ6 5 +Associative learning 0.5854971824021584 1.540397597527302 0.1234634666763754 1.0 0.4634893018152561 11 P50897,O00264,Q13641 3 +Regulation of tor signaling 0.5415049728119778 1.5368870409894648 0.1243209734839732 1.0 0.4661676363779111 14 P04062,O75844,Q9H4A6 3 +Establishment of protein localization to endoplasmic reticulum 0.4783874172479951 1.5342803180287443 0.1249607056219157 1.0 0.4680241242968974 22 Q99442,P61026,Q15629,Q9UGP8,P61619,O43681,Q9Y5M8,Q15005 8 +Negative regulation of release of cytochrome c from mitochondria 0.6639873799374192 1.5314137368032574 0.1256671712096053 1.0 0.4701259722939687 7 Q9H300,Q9H3K2 2 +Bone mineralization 0.6184104632399487 1.526800078979835 0.1268107319634543 1.0 0.472492260948461 8 Q4KMQ2,P17302,O75844 3 +Response to ph 0.7498036563220511 1.5256031316565049 0.1271087317451726 1.0 0.4732729843383726 5 P04062,P51798 2 +Amino acid import across plasma membrane 0.7076972431992264 1.5216650897328057 0.1280930191718596 1.0 0.4745380767488699 6 P30825 1 +Regulation of lipid catabolic process 0.6172651875706422 1.5207970362227483 0.1283107784176533 1.0 0.474801233801631 8 P11802,P31751,Q8WTV0,Q8NCG7 4 +Regulation of membrane invagination 0.802565707133932 1.5161050684981978 0.129492786903004 1.0 0.4782135723132141 2 Q4KMQ2 1 +Vascular process in circulatory system 0.4474237985553805 1.5156717261575177 0.1296023803827839 1.0 0.4782135723132141 28 P41440,P42892,Q8WWI5,P23634,Q93063,P08183,P14672,Q9HB40,P20020,P30825,Q96QD8 11 +Regulation of steroid biosynthetic process 0.592958379529157 1.5145401146589057 0.1298889076606153 1.0 0.4787249489632702 10 Q12770,Q9UBM7,P05023,Q13510,P16435 5 +Regulation of glucose transmembrane transport 0.5919370086436879 1.5088927475351603 0.1313261935154608 1.0 0.4818271680453869 10 P31751,P52789,O75298 3 +Positive regulation of voltage gated calcium channel activity 0.8006883604505608 1.5076419749833951 0.1316461836592743 1.0 0.4819824799992852 2 O75323 1 +Inositol phosphate catabolic process 0.7785117852997108 1.5067113435562938 0.1318846626606136 1.0 0.4821491115451557 4 Q10713 1 +Ubiquitin dependent erad pathway 0.4034695281850731 1.5061021837089832 0.1320409441353351 1.0 0.4821491115451557 38 Q9UBU6,Q96CS3,P51572,Q96A33,P27824,Q9GZP9,Q9UKV5,O60858,Q9UBV2,Q8TCJ2,Q6NTF9,Q9UMX0 12 +Cerebellar purkinje cell layer development 0.6029627186602465 1.505352723956867 0.1322334167170351 1.0 0.4821491115451557 9 P04062,O14949 2 +Vesicle targeting 0.4890553346976224 1.501787600209752 0.1331519716800007 1.0 0.4841345846702048 18 P49755,Q9UBV8,Q9NR31,Q9HCU5,Q9BVK6,O75340,Q15363,Q9Y6B6,O15498,O15027 10 +Regulation of store operated calcium entry 0.7991239048811194 1.5005884243205498 0.1334620471871384 1.0 0.4848789800565578 2 Q96BY9 1 +Terpenoid metabolic process 0.488749209356996 1.4996137682119268 0.1337144791471269 1.0 0.4848789800565578 18 P14324,Q6UX07,Q8NBN7,P37268,Q9HBH5,Q9HB40,Q8TC12,P51648,P48449,Q9Y394 10 +Glycolipid catabolic process 0.657398927847061 1.4990230309244694 0.1338676573901449 1.0 0.4848789800565578 7 P04062 1 +Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process 0.7984981226533377 1.4977667704069175 0.1341938571108629 1.0 0.48536422374519 2 Q7LGA3 1 +Fatty acid transmembrane transport 0.6570677459070206 1.4973928008661703 0.1342910804113486 1.0 0.48536422374519 7 P31751,P28288,P50416,P23786,O14678 5 +Cell maturation 0.4601482777129608 1.4964395233444971 0.134539156563928 1.0 0.48536422374519 25 O75503,Q8N2A8,P04062,Q86UL3,P17302,Q9NZJ7,Q8IXJ6,Q9Y2W6 8 +Antigen processing and presentation of endogenous peptide antigen 0.6567109640291173 1.4956363404941486 0.1347484477110108 1.0 0.48536422374519 7 Q6P179,P04439,Q9NZ08,Q03519 4 +Antigen processing and presentation of endogenous antigen 0.6567109640291173 1.4956363404941486 0.1347484477110108 1.0 0.48536422374519 7 Q6P179,P04439,Q9NZ08,Q03519 4 +Peroxisome organization 0.5489940882709778 1.492015423950862 0.1356951019347378 1.0 0.4870577461984651 13 P40855,O96011,P28288,O75381,Q9Y3D6,Q7Z434,P56589,O14678 8 +Glucose import 0.5769294035717506 1.4917243822347148 0.1357714144810815 1.0 0.4870577461984651 11 Q9BZF1,P31751,P52789,O75298 4 +Chondrocyte differentiation 0.5488636339571529 1.4912227105570708 0.1359030330180666 1.0 0.4870577461984651 13 Q9C0E8,Q92543,Q9NX62,Q15043,P16435 5 +Lipoprotein localization 0.7745773324984239 1.4899853871610271 0.1362280782292715 1.0 0.4876482977322153 4 O15260,Q13432,Q5JRA6 3 +Positive regulation of response to endoplasmic reticulum stress 0.6113002796631157 1.489484268340006 0.1363598929060463 1.0 0.487754709181055 8 P51572,P57088,Q4ZIN3,Q9UMX0 4 +Homologous chromosome pairing at meiosis 0.655242150046331 1.4884029296585444 0.136644664449975 1.0 0.4877905506454707 7 Q92791,O94901,Q9BTX1 3 +Signaling receptor ligand precursor processing 0.7735270554383435 1.485518244913271 0.1374065939809863 1.0 0.4894306418519226 4 P42892,Q8TAD4 2 +Protein o linked glycosylation via threonine 0.8691808688720606 1.484941612168465 0.1375592916988375 1.0 0.4895712030778888 3 Q10472 1 +Regulation of erad pathway 0.6104088477068655 1.4847979873200654 0.1375973452408343 1.0 0.4895712030778888 8 P51572,Q4ZIN3,Q9UMX0 3 +Positive regulation of mitophagy 0.7403400338637842 1.483854371970846 0.1378475589031862 1.0 0.4899029020433127 5 P27544,P21796,P12235 3 +Neuromuscular junction development 0.598592600262827 1.4817894145022803 0.1383963365725524 1.0 0.4905263364170643 9 O15258,P49354,Q9Y4W6 3 +Phosphatidylethanolamine metabolic process 0.7719625469468083 1.4788622073689968 0.1391771458133264 1.0 0.4920720975323226 4 Q9UG56 1 +Regulation of autophagy of mitochondrion 0.5018429526513664 1.478729555587355 0.1392126097932142 1.0 0.4920720975323226 16 Q9H300,P21796,P12235,P27544 4 +Hydrogen sulfide metabolic process 0.7941176470588411 1.4780118225682202 0.139404613827919 1.0 0.4924818016890239 2 Q9Y6N5 1 +Neuron recognition 0.7714177818119043 1.4765440857812504 0.1397978894007239 1.0 0.4934751352311768 4 Q9NQC3 1 +Glycoside catabolic process 0.6977891009400723 1.4758473298646302 0.1399848816083198 1.0 0.4936434266767221 6 P04062,P04066,P08236,Q9BTY2 4 +Disaccharide metabolic process 0.7934918648310362 1.4751892514866938 0.1401616703721475 1.0 0.4936434266767221 2 P15291 1 +Protein o linked glycosylation 0.485194014254293 1.474337551623808 0.1403907293071979 1.0 0.4938091304761877 18 Q8N4A0,O60502,Q11206,Q10472,Q9H5K3 5 +Neurotransmitter metabolic process 0.7701390740968401 1.4711018914422282 0.1412635636040597 1.0 0.4942148177324423 4 Q8NCG7 1 +Establishment of protein localization to organelle 0.3084900015380459 1.4691134286108531 0.1418020260443038 1.0 0.4942148177324423 186 Q99595,Q8NFH5,Q9Y512,Q8N4H5,Q7Z3B4,P46379,P40855,P13473,Q9Y371,P51572,Q7Z434,Q3ZCQ8,Q9NS69,P56589,Q8N8Q8,Q9P0J0,P62072,Q14108,Q8TB36,Q9H300,P11279,Q99442,Q15629,P61619,Q99623,Q9Y5M8,O43681,Q9H1Z9,Q15070,P52789,P61026,O75381,O96008,O14925,Q9UGP8,Q10713,O43615,Q8WWC4,Q53H12,P49257,Q15005 41 +Glial cell proliferation 0.8637588930040663 1.4630431477342871 0.1434555727761823 1.0 0.4942148177324423 3 Q96G23 1 +Regulation of amino acid transport 0.6944437035617878 1.460347001914891 0.1441947304827855 1.0 0.4942148177324423 6 O75915,Q15042,Q15041,Q7L0J3 4 +Carbohydrate transmembrane transport 0.5437878783082177 1.4603388810564186 0.1441969612459781 1.0 0.4942148177324423 13 Q9BZF1,P31751,P52789,O75298 4 +Organelle membrane fusion 0.4238489116005804 1.4601544673598543 0.1442476259785707 1.0 0.4942148177324423 31 P31751,Q9BSR8,O14653,Q8IWA4,O60499,Q9UNK0,O95249,Q12981,O15400 9 +Ribonucleoside triphosphate biosynthetic process 0.418892156817048 1.4595669958950384 0.1444091154034767 1.0 0.4942148177324423 32 P00846,O75964,P00403,P56385,P24539,P36542 6 +Biomineralization 0.5576179388263043 1.459151927360829 0.1445232966748868 1.0 0.4942148177324423 12 Q13586,Q6P4Q7,O75844,Q4KMQ2,P17302,P18074,P20020 7 +Positive regulation of macroautophagy 0.4638825375796901 1.4576569394295995 0.1449351265829768 1.0 0.4947363603613005 23 P09601,Q9Y371,O15269,O60858,P12235,P27544,P21796 7 +Hippocampus development 0.4826001003003713 1.4547119401830764 0.1457490256248568 1.0 0.4967286434144672 17 P23634,P07196,P18887,O14949,P49841,Q13144 6 +Positive regulation of organic acid transport 0.692947021850066 1.4534076234837048 0.1461106110721477 1.0 0.4969851484126378 6 P14174,Q15042,Q15041,P33121 4 +Homologous chromosome segregation 0.6044180236044309 1.4532599695102115 0.1461515872391778 1.0 0.4969851484126378 8 Q92791,O94901,Q9BTX1 3 +Regulation of microtubule based movement 0.7646841509374598 1.4478711951889358 0.1476530768502346 1.0 0.5007569258189258 4 Q7Z4L5 1 +Cell recognition 0.4710591178387768 1.447686584131705 0.1477047236384934 1.0 0.5007569258189258 21 P45880,Q9NQC3,Q8WTV0,P35613 4 +Protein localization to membrane raft 0.6912494051871718 1.445533118223207 0.1483081974838631 1.0 0.5022766374231095 6 Q9BRK0 1 +Alpha ketoglutarate transport 0.7866082603254199 1.4441354241425275 0.1487008852361893 1.0 0.5024208142643625 2 Q9BQT8 1 +Pigment metabolic process 0.43895889713511 1.44408464427608 0.1487151669747617 1.0 0.5024208142643625 28 Q9P0S9,P09601,Q7KZN9,P30519,P22830,P36551,O00264 7 +Production of sirna involved in rna interference 0.785982478097619 1.4413119500097855 0.1494965727638675 1.0 0.5044108065228881 2 Q15631 1 +Negative regulation of glycoprotein metabolic process 0.7630572414060237 1.4409383687963755 0.1496020951594583 1.0 0.5044108065228881 4 Q9Y287,Q9BXS4 2 +Peroxisome fission 0.7618922478080512 1.43597274671409 0.1510100963920213 1.0 0.5062587423913285 4 P40855,O96011 2 +Isoprenoid metabolic process 0.456764599082929 1.4343528591201318 0.1514715929830297 1.0 0.5062587423913285 24 P14324,Q9H3H5,Q86SQ9,Q8NBN7,Q9HBH5,Q8TC12,P51648,P04035,P37268,Q9Y394 10 +Cardiolipin acyl chain remodeling 0.7837922403003937 1.4314294355793429 0.1523071772125597 1.0 0.5062587423913285 2 P40939 1 +Mitochondrial electron transport nadh to ubiquinone 0.4423786421694927 1.429810699793569 0.152771357309565 1.0 0.5062587423913285 27 Q9Y375,O75208,O95298,O96000,O75306,Q9Y6M9,P03915,O95169,O95139,O43676,P03886 11 +Neuron cellular homeostasis 0.6868866912013196 1.4252797819661784 0.1540763420631634 1.0 0.5062587423913285 6 P20020,P23634,P51790 3 +Positive regulation of mitochondrial membrane potential 0.7593005298984592 1.424922483606683 0.1541796096146037 1.0 0.5062587423913285 4 Q8IWA4 1 +Attachment of gpi anchor to protein 0.726468321603049 1.4224891795776329 0.1548842904952669 1.0 0.5062587423913285 5 Q92643,O43292,Q9H490 3 +Negative regulation of peptide secretion 0.6415162793801811 1.420632147509096 0.1554237276361085 1.0 0.5062587423913285 7 P40939,Q8N5M9 2 +Positive regulation of membrane potential 0.7260153647745344 1.4204822878479315 0.1554673215045277 1.0 0.5062587423913285 5 Q8IWA4 1 +Protein o linked glycosylation via serine 0.7259029769548555 1.4199843084450257 0.1556122493590854 1.0 0.5062587423913285 5 Q10472 1 +Atp biosynthetic process 0.4588367964576097 1.418481985136432 0.1560500945670671 1.0 0.5062587423913285 23 P00846,O75964,P00403,P56385,P24539,P36542 6 +Amino acid import 0.5868586714883481 1.4183066122937409 0.1561012670370898 1.0 0.5062587423913285 9 Q9H9B4,Q96NB2,Q15041,P30825 4 +Protein depalmitoylation 0.7576461920750794 1.4178665147061469 0.1562297402466943 1.0 0.5062587423913285 4 P50897 1 +Regulation of toll like receptor 3 signaling pathway 0.7573494367346314 1.416600621827104 0.1565997266313004 1.0 0.5063330701604776 4 P41440 1 +Neutrophil differentiation 0.7569587908369166 1.4149341246656773 0.1570878115138796 1.0 0.5074021694138613 4 Q8N5M9 1 +Regulation of electron transfer activity 0.7800375469336641 1.4144871239747288 0.1572189253233697 1.0 0.5074021694138613 2 Q99623 1 +Mitochondrion distribution 0.7564752299527179 1.4128711144705497 0.1576936236736692 1.0 0.5074021694138613 4 O75153 1 +Vacuolar proton transporting v type atpase complex assembly 0.8513302034428651 1.4128073495469464 0.1577123766889065 1.0 0.5074021694138613 3 Q92544,Q8N511 2 +Proton transporting v type atpase complex assembly 0.8513302034428651 1.4128073495469464 0.1577123766889065 1.0 0.5074021694138613 3 Q92544,Q8N511 2 +Macroautophagy 0.3245178947326546 1.4106702910756888 0.158341854877591 1.0 0.508579893184997 107 Q9Y487,O60858,P09601,Q9Y371,O15269,P12235,O15118,P21796,Q5T8D3,Q9Y6I9,Q9H0U4,P62820,Q99623,Q86VR2,Q9UMX0,P16615,Q7Z3C6,Q93050,P04062,O14681,P27544 21 +Toll like receptor 3 signaling pathway 0.683658805701269 1.4102798390654896 0.1584570691655 1.0 0.5086974958527363 6 P41440,Q14699,Q14254,Q9UMX0 4 +Er overload response 0.7226204868252197 1.405434979850726 0.1598919711626849 1.0 0.5107704034377576 5 Q96A33,Q9UM00,P49841 3 +Cholesterol storage 0.849142945463932 1.4039623007882756 0.1603300759458574 1.0 0.5116648183045313 3 Q8WTV0 1 +Peptidyl proline hydroxylation 0.6380935620335436 1.403685699593942 0.1604124626837308 1.0 0.5116754354308064 7 Q96HE7,P13674,Q32P28,O15460,O75718 5 +Negative regulation of macroautophagy 0.5841063965340654 1.4033729515889783 0.1605056544280707 1.0 0.5116947715093695 9 P09601 1 +Neurofilament cytoskeleton organization 0.7772215269086324 1.4017801602683675 0.1609809047009616 1.0 0.5123645303020514 2 P07196 1 +Forebrain regionalization 0.7769086357947663 1.4003682836773028 0.1614030625330249 1.0 0.5130651378751167 2 Q7Z4L5 1 +Macromolecule depalmitoylation 0.7202018782152918 1.3947087891367065 0.1631036734057809 1.0 0.5167849292508301 5 P50897 1 +Paranodal junction assembly 0.8468264489970876 1.394593563706847 0.1631384370858342 1.0 0.5167849292508301 3 O15228 1 +Regulation of morphogenesis of a branching structure 0.8467729151599308 1.3943770420774484 0.1632037770897763 1.0 0.5167849292508301 3 Q9NQC3 1 +Xenobiotic transport 0.7520350657482591 1.3939212382169592 0.1633413900803817 1.0 0.5167849292508301 4 P41440,P17302,P08183 3 +Mitochondrial adp transmembrane transport 0.8466353677621248 1.3938207189944511 0.1633717498836699 1.0 0.5167849292508301 3 P12236,P12235 2 +Nucleobase transport 0.8466353677621138 1.393820718994407 0.1633717498836833 1.0 0.5167849292508301 3 Q9Y277,P12235 2 +Negative regulation of chromatin binding 0.7515006207364272 1.3916395138578717 0.1640315870342428 1.0 0.5177904471552129 4 Q7L2J0,Q7Z5K2 2 +Glucosylceramide metabolic process 0.8451845327965578 1.3879524907662832 0.1651515124535458 1.0 0.5181712805117091 3 P04062 1 +Phospholipid dephosphorylation 0.7496776278591866 1.3838553140756746 0.1664027618914871 1.0 0.520126838170079 4 Q10713 1 +Negative regulation of cyclic nucleotide phosphodiesterase activity 0.7728410513141559 1.3820144370376328 0.1669672682961982 1.0 0.520126838170079 2 Q15043 1 +Regulation of protein kinase a signaling 0.7728410513141393 1.3820144370375578 0.1669672682962213 1.0 0.520126838170079 2 P14174 1 +Regulation of mitochondrial membrane permeability 0.4876183965783463 1.3818891879933215 0.1670057282427934 1.0 0.520126838170079 16 P05141,Q969V5,P12235,P45880,P52789 5 +Membrane biogenesis 0.453905759037193 1.3800784441694325 0.1675624934463249 1.0 0.520126838170079 23 P41440,Q9H6H4,Q86XL3,Q6NUK4,Q8IXJ6 5 +Mitochondrial fission 0.4860700489414823 1.3713031105260869 0.1702804864572402 1.0 0.5263650753511727 16 Q9UDX5,O60313,Q969V5 3 +Negative regulation of axonogenesis 0.6752669454519511 1.3712271685447042 0.1703041513883429 1.0 0.5263650753511727 6 Q8N0X7,Q9NQC3 2 +Granulocyte differentiation 0.6310044336761459 1.3685310059081788 0.1711459235210517 1.0 0.5278878945215452 7 Q8N5M9 1 +Estrogen metabolic process 0.7137861966330195 1.3662332721900163 0.1718657573971935 1.0 0.5288852732065203 5 Q53GQ0,O95470 2 +Cerebral cortex cell migration 0.5549313972518458 1.3658798314646046 0.1719766840494676 1.0 0.5288852732065203 11 Q96N66,Q9NQC3 2 +Negative regulation of anion transport 0.7690863579474307 1.3650740912446573 0.1722297642375729 1.0 0.5290322895802431 2 Q9HD26 1 +Negative regulation of anion transmembrane transport 0.7690863579474307 1.3650740912446573 0.1722297642375729 1.0 0.5290322895802431 2 Q9HD26 1 +Negative regulation of endoplasmic reticulum calcium ion concentration 0.7681476846057769 1.3608393803253165 0.1735644539267347 1.0 0.531115435373069 2 P51572 1 +Negative regulation of fatty acid transport 0.7681476846057538 1.360839380325212 0.1735644539267677 1.0 0.531115435373069 2 P31751 1 +Positive regulation of cell junction assembly 0.575546512746441 1.3568286914439391 0.174835648749545 1.0 0.5329157943677367 9 Q13641 1 +Regulation of insulin secretion 0.4657851260762434 1.3567002364356873 0.1748764773348095 1.0 0.5329157943677367 19 P50416,Q9BRT2,P00367,Q08209,Q8N5M9,P40939,Q16836,O95563 8 +Glycerolipid catabolic process 0.5752310926878219 1.3551108400513243 0.1753822455097191 1.0 0.5329157943677367 9 Q8N2K0,Q8WTV0,Q8NCG7 3 +Intermembrane lipid transfer 0.5858534303879913 1.3550701265744114 0.175395215428084 1.0 0.5329157943677367 8 Q9H1P3,P48739,Q9Y3B1,Q00169 4 +Negative regulation of protein exit from endoplasmic reticulum 0.8368847936561756 1.3543772602381077 0.1756160486191593 1.0 0.5329157943677367 3 Q8NBM4 1 +Leukocyte migration 0.3778974734691589 1.3538481795313837 0.1757848189856725 1.0 0.5329157943677367 44 P09601,P04062,Q11206,Q08722,Q9H4A6,Q4KMQ2,Q8N5M9 7 +Positive regulation of amyloid precursor protein biosynthetic process 0.7665832290362988 1.3537819441855756 0.1758059557790043 1.0 0.5329157943677367 2 P35610 1 +Endochondral bone morphogenesis 0.6273757332785164 1.350509066648724 0.176852747373339 1.0 0.5343804333405822 7 Q9NX62,O75844 2 +L aspartate transmembrane transport 0.741489089131349 1.3488685736782773 0.177379183944264 1.0 0.5351972393880077 4 Q9H936,Q9UJS0 2 +Ribonucleoside triphosphate metabolic process 0.382723922727988 1.3467737879897452 0.1780530991930689 1.0 0.5358443020325457 41 P00846,O75964,P00403,P56385,P56134,P24539,P36542,Q8IWA4 8 +Leukocyte apoptotic process 0.4666741972452772 1.3418037104789935 0.1796596488243098 1.0 0.5374820915244491 18 P24390 1 +Leukocyte degranulation 0.5828867117641578 1.3393194780088848 0.1804666903985896 1.0 0.5381722352581063 8 P09601 1 +Magnesium ion transport 0.738885410143996 1.3377373962933252 0.1809820558903581 1.0 0.5390316915427509 4 Q9H0U3,Q9HD23,Q8N4V1 3 +Aspartate transmembrane transport 0.7068587535233273 1.3354524635184608 0.1817283036763264 1.0 0.5398740414183864 5 Q9H936,Q8TDW0,O75746,Q9UJS0 4 +Cellular sodium ion homeostasis 0.7064919790285353 1.333821878250795 0.1822622390637067 1.0 0.5411014730368395 5 Q96PU5 1 +Regulation of body fluid levels 0.3672733747179571 1.3308931204895722 0.1832241812112518 1.0 0.5419684190124415 50 Q9UNS2,P38435,P00403,P04062,Q16739,P52789,Q86UL3,Q11206,Q9BWH2,Q13505,Q4KMQ2 11 +Cellular lipid catabolic process 0.3616916506301209 1.3296029580674815 0.1836491229931418 1.0 0.542366279954682 65 Q15067,Q8NCG7,Q8N2K0,P40939,O95470,P50897,P35610,P17900,O14678,Q16836,O15254,Q709F0,P23786,Q8IXJ6,P31751,O43808,Q99735,P04062,A1L0T0,Q13510,Q8WTV0 21 +Lipid homeostasis 0.4349407597938303 1.328864995452071 0.1838925142718888 1.0 0.542366279954682 26 Q9NQC3,Q9HCL2,O15254,Q15067,O15118,Q9BWH2,Q8WTV0,O15260,Q9Y6C9 9 +Protein exit from endoplasmic reticulum 0.4434413600670386 1.328705043173935 0.1839453004481654 1.0 0.542366279954682 24 Q92544,Q8NBM4,Q9NR31,P51572,Q9GZP9,Q9UBV2,Q9BVK6,P49257,O15260 9 +Arachidonic acid metabolic process 0.6660576210336928 1.3282857166534274 0.184083736509413 1.0 0.5425272963064304 6 P07099,Q9H7Z7,Q8NCG7 3 +Long chain fatty acid import across plasma membrane 0.7603254067584461 1.3255588605700708 0.1849858606238732 1.0 0.5433768868209344 2 P31751 1 +Regulation of long chain fatty acid import across plasma membrane 0.7603254067584461 1.3255588605700708 0.1849858606238732 1.0 0.5433768868209344 2 P31751 1 +Positive regulation of fatty acid transport 0.7603254067584443 1.325558860570064 0.1849858606238754 1.0 0.5433768868209344 2 P14174 1 +Membrane raft organization 0.5584995185181463 1.3226438402135678 0.1859538477648894 1.0 0.5439407938632853 10 P50897,P41440 2 +Folic acid metabolic process 0.6215675557346247 1.3216267510405144 0.18629247093086 1.0 0.5441619878159871 7 Q9H2D1 1 +Peptidyl asparagine modification 0.5583058383287166 1.3215579742262784 0.1863153854823906 1.0 0.5441619878159871 10 Q9H0U3,Q8TCJ2,P46977 3 +Synaptic transmission gabaergic 0.7035257145789988 1.3206315947521907 0.1866242327605054 1.0 0.5447470372818389 5 Q13641 1 +Phosphatidylethanolamine biosynthetic process 0.8282212545797283 1.319327135138379 0.1870597699044558 1.0 0.5450272636331224 3 Q9UG56 1 +Phosphatidylcholine biosynthetic process 0.5685884772610538 1.3188904212503354 0.187205748927137 1.0 0.5450272636331224 9 Q8WWI5,Q86UL3,Q8NF37,Q9Y6K0,P35790 5 +Neuron apoptotic process 0.3705647268594872 1.3184402827088777 0.1873563033908147 1.0 0.5452203217380186 46 P50897,Q99720,P09601,P04062,Q96A26,Q01105 6 +Neuromuscular process 0.4288642686537277 1.3167083160999191 0.1879364150101561 1.0 0.545593555103288 27 Q8N0X7,O14773,P78417,P04062,P07196,O75844,P18887,P17900,Q9H5K3 9 +Regulation of alcohol biosynthetic process 0.7025262522509914 1.3161860489437136 0.1881116050477715 1.0 0.545593555103288 5 P16435,Q12770 2 +Regulation of cholesterol biosynthetic process 0.7025262522509914 1.3161860489437136 0.1881116050477715 1.0 0.545593555103288 5 P16435,Q12770 2 +Neutral lipid catabolic process 0.8272138172641949 1.315251533112656 0.1884253810218261 1.0 0.545593555103288 3 Q8NCG7 1 +Negative regulation of cellular response to growth factor stimulus 0.5453380897346689 1.3106415878494733 0.1899788817776717 1.0 0.5476129103543744 11 Q8N0X7,P23634,Q8NC56,O75340 4 +Regulation of response to wounding 0.4621344090085075 1.309211169613682 0.1904628297000881 1.0 0.5476129103543744 17 Q11206,Q96G23 2 +Polyol metabolic process 0.4557259814844513 1.306208467696921 0.1914816740059677 1.0 0.5484068689511803 20 P04062,Q10713,Q9NX62 3 +Forebrain cell migration 0.5314314858206423 1.3039287297563242 0.1922578835796899 1.0 0.5498422547625954 12 Q96N66,Q9NQC3 2 +Negative regulation of gliogenesis 0.6995522304300592 1.3029545150037969 0.19259029067485 1.0 0.5503065612572314 5 Q96G23 1 +Tor signaling 0.4605415676144014 1.2976186097020683 0.1944184240927475 1.0 0.5540625454549811 18 P04062,O75844,Q9H4A6 3 +Membrane docking 0.4215688881228471 1.295730670398317 0.1950682908709193 1.0 0.5545183656050934 28 P61026,O60499,Q9UNK0,Q6IQ22,O15400,O15498,P16615 7 +Negative regulation of developmental growth 0.5426691935135469 1.2952394768800732 0.1952376304507765 1.0 0.5545845585505776 11 Q9NQC3 1 +Long chain fatty acid transport 0.5168333746276972 1.295095998606343 0.1952871151014781 1.0 0.5545845585505776 13 P31751,P14174,P28288,O14975,O14678,P23786,P50416 7 +Regulation of pattern recognition receptor signaling pathway 0.459933876501239 1.293232777179463 0.1959305624685736 1.0 0.5554827448174717 18 P41440,Q9NPR9,Q9NQC3,O43657 4 +Cellular modified amino acid catabolic process 0.5629340519762381 1.28799650005039 0.1977471815199913 1.0 0.5584173636357518 9 Q9UHG3,Q8NBM8 2 +Xenobiotic transport across blood brain barrier 0.7515644555694838 1.286072219575491 0.1984178583687912 1.0 0.5585734577481892 2 P08183 1 +Sphingolipid translocation 0.7515644555694838 1.286072219575491 0.1984178583687912 1.0 0.5585734577481892 2 P08183 1 +Cobalamin transport 0.751564455569468 1.2860722195754195 0.1984178583688161 1.0 0.5585734577481892 2 O14678 1 +Tripeptide transmembrane transport 0.7515644555694576 1.286072219575371 0.1984178583688329 1.0 0.5585734577481892 2 P17302 1 +Modified amino acid transport 0.5727726019158692 1.285512720085917 0.1986131746371224 1.0 0.5588802027180246 8 Q9H2D1,Q96QD8 2 +Fatty acid metabolic process 0.3205626848589158 1.283030882507662 0.1994812567479944 1.0 0.5596197198409276 100 O00767,Q9HCL2,Q15067,Q9H7Z7,Q8NCG7,O15228,Q8N2K0,P40939,O95470,Q15800,P35610,Q9P035,P51648,Q53GQ0,Q5T8D3,O14678,Q16836,Q9NZ01,O15254,Q6Y1H2,Q709F0,Q8N4Q0,P23786,P07099,Q92604,P31751,O43808,Q12770,Q86UL3,A1L0T0,Q13510,P50416,P16435 33 +Hindbrain morphogenesis 0.5277645479489368 1.282061350173964 0.1998211257405593 1.0 0.5600876248561715 12 Q7Z4L5,P04062,O15020,P18887,O15228 5 +Mitochondrial proton transporting atp synthase complex assembly 0.8178403755868391 1.2773375955270392 0.2014830860736876 1.0 0.5625613689488465 3 Q15070,Q9BUB7 2 +Phosphatidylinositol dephosphorylation 0.8177192181304009 1.2768476417844574 0.2016560420100777 1.0 0.5625613689488465 3 Q10713 1 +Cellular response to insulin like growth factor stimulus 0.7493742177722362 1.2762067725214954 0.2018824352033914 1.0 0.5625613689488465 2 Q9BSK2 1 +Regulation of multicellular organism growth 0.486467922708423 1.2760857698072967 0.201925201356383 1.0 0.5625613689488465 15 P11802,Q9HCL2,O75844,Q86UL3,O95470 5 +Inositol phosphate metabolic process 0.6934637565317374 1.2758529306852466 0.2020075125829912 1.0 0.5625613689488465 5 Q10713 1 +Regulation of necrotic cell death 0.5262099910820135 1.2727822659289854 0.2030953158299948 1.0 0.5638922711504619 12 P12235,Q13510,P00403 3 +Leukocyte mediated cytotoxicity 0.4991949088920496 1.2688927352047978 0.2044793237400166 1.0 0.567125395889142 14 O15400,P15151,P04439,P11279 4 +Learning 0.4565478297947125 1.268771247353758 0.2045226628561893 1.0 0.567125395889142 18 P50897,P04035,O00264,Q13641 4 +Iron ion transmembrane transport 0.8156494522691451 1.2684781873518731 0.2046272354685716 1.0 0.5671723631488632 3 Q15043,Q8N4V1 2 +Negative regulation of transport 0.3465414604637271 1.268006188795403 0.2047957404742184 1.0 0.5673902915329033 77 P31751,Q8IZ07,P40939,Q8NBM4,P09601,P55061,Q9GZP9,Q13432,Q16850,Q96PU5,P21796,Q08722,P04035,P49257,Q16836,Q8N5M9,Q9UMX0 17 +Regulation of dna templated transcription in response to stress 0.5250569665037056 1.2658966765752813 0.2055500764180431 1.0 0.5681000882635824 12 P09601,P55061,Q8IXJ6 3 +Protein kinase b signaling 0.4225943836495813 1.2639202981313515 0.2062586354565228 1.0 0.5681000882635824 27 Q9NQC3,Q969V5,Q13641,O75340,Q86UE4 5 +Polyol catabolic process 0.6522715115793223 1.263864636085943 0.2062786167211709 1.0 0.5681000882635824 6 Q10713 1 +Regulation of transport 0.2924682544904879 1.2631067499390716 0.2065508185437008 1.0 0.5683078236914765 323 P14174,Q9BVC6,Q6IQ22,Q7Z3B4,O75298,P50897,P09601,O75844,Q7Z434,Q4J6C6,P17302,P21796,Q9H4A6,Q9Y282,P20020,P23634,Q969V5,O75323,P57105,Q9P2W9,Q8TAD4,O95563,P49841,P16615,Q9HD26,Q14012,Q13636,Q8N5M9,Q00535,Q9BZF1,Q13586,Q08J23,P27105,P55786,Q9BRT2,P61978,Q9BRK0,Q13546,Q9Y371,Q9H300,Q7Z4L5,Q96KC8,Q96PU5,P52789,Q32P28,Q96BY9,Q9NR31,P55061,Q13432,P04035,Q8WTV0,Q92544,P50402,Q8NBM4,Q08722,P40939,Q4KMQ2,Q15041,Q7L0J3,P41440,Q00765,P08183,P51572,Q16850,Q16836,P98194,P11279,O14966,P49755,Q9GZP9,Q9UMX0,P61026,P49257,O15260,Q8NBU5,Q96HR9,Q8IZ07,Q99623,P00367,P31751,P78417,P05141,P05023,P50416 84 +Cellular response to increased oxygen levels 0.6520348453636832 1.262757489947237 0.2066763462482663 1.0 0.5683078236914765 6 Q9Y487,Q8N511 2 +Diacylglycerol metabolic process 0.8141020736940386 1.2622218418105406 0.2068689713959535 1.0 0.5685163409234018 3 Q9HCL2 1 +Energy derivation by oxidation of organic compounds 0.3138773628816718 1.2608894797506434 0.2073486690314607 1.0 0.5688684128747834 135 O95298,Q7KZN9,O96000,Q9BRT2,Q9Y6M9,O14949,O95139,P10253,O43676,P03886,Q13423,P46020,P13807,P00403,P24539,Q9H3K2,P20674,Q9H936,Q9Y375,O75208,O75964,Q9BSK2,P56385,P13073,O75323,P03915,Q15070,P49841,P31751,P00846,P21912,P04062,P56134,O75306,O43819,O95169,P36542,Q8NFG4,Q9UDW1,P51970 40 +Regulation of epithelial cell apoptotic process 0.5678576402425612 1.2593087365535254 0.2079188388368906 1.0 0.5699565089050921 8 P09601 1 +Intraciliary transport involved in cilium assembly 0.7456195244055113 1.2593016359050933 0.2079214025841969 1.0 0.5699565089050921 2 A0AVF1 1 +Zinc ion homeostasis 0.7196736218137362 1.2555372557689943 0.2092837923906516 1.0 0.5725452368092172 4 Q8TAD4 1 +Regulation of leukocyte mediated cytotoxicity 0.5671382091339583 1.2554702505371602 0.2093081010955821 1.0 0.5725452368092172 8 O15400,P15151,P11279 3 +Positive regulation of cell killing 0.5671382091339583 1.2554702505371602 0.2093081010955821 1.0 0.5725452368092172 8 O15400,P15151,P11279 3 +Cognition 0.37687411794658 1.25416803112944 0.2097809370336465 1.0 0.5732517471811689 39 P50897,Q8NBU5,Q9H0U3,Q13641,Q11206,P17900,P04035,O00264,Q9H5K3 9 +Cellular response to leucine 0.7443679599499329 1.253668753165461 0.209962429831001 1.0 0.5732517471811689 2 Q9P2J5 1 +Response to leucine 0.7443679599499329 1.253668753165461 0.209962429831001 1.0 0.5732517471811689 2 Q9P2J5 1 +Copii coated vesicle cargo loading 0.5354026603631273 1.253234082845056 0.2101205295999553 1.0 0.5732517471811689 11 Q12770,Q9NR31,P62820,Q5JRA6,P55735 5 +Adaptive thermogenesis 0.4375864107683456 1.2522011417587469 0.2104965800839895 1.0 0.5736142594962442 23 Q9UIQ6,O00767,P05141,P12235,P17302,Q8NFG4,P23786,P40939,Q16836,Q6IAN0 10 +Striated muscle adaptation 0.6878018687679874 1.2506364661126974 0.2110671399045907 1.0 0.5737517557913299 5 P23634,P16615 2 +Nuclear membrane organization 0.4404024132837938 1.24358165517247 0.2136535712877363 1.0 0.5775964550435378 22 O14657,P50402,Q9H6H4,Q86XL3,Q6NUK4 5 +Protein import into peroxisome matrix 0.7418648310388185 1.2424065220489036 0.2140866104826635 1.0 0.5778314431005704 2 O75381 1 +Skeletal system morphogenesis 0.4467979036336099 1.2395964262536154 0.2151247031641174 1.0 0.5796365857111442 20 Q7Z3C6,Q93063,O75844,Q9NX62,P16435,O95470,Q92896 7 +Antigen processing and presentation of exogenous peptide antigen 0.8079782082695672 1.2374694043659211 0.2159128661965539 1.0 0.5807930465603063 3 Q9UIQ6 1 +Fat soluble vitamin metabolic process 0.684081453010356 1.2340611961665964 0.2171801015774994 1.0 0.5824471932042558 5 P04062,Q8N0U8 2 +Negative regulation of amyloid beta clearance 0.8066645665762662 1.232161521671959 0.2178887536992964 1.0 0.5824471932042558 3 P04035 1 +Nucleoside triphosphate biosynthetic process 0.3760710713789188 1.2316148359565793 0.2180929962962379 1.0 0.5824471932042558 38 P00846,O75964,P00403,P56385,P24539,P36542 6 +Organic hydroxy compound metabolic process 0.3130312087165573 1.2314973532518914 0.2181369059662381 1.0 0.5824471932042558 106 P14324,Q9H3H5,Q9HBH5,Q15392,Q14739,Q15800,Q8NBN7,P35610,Q16850,O15269,O15118,P51648,O75845,P38435,Q14534,P37268,Q9H1P3,Q9Y394,Q12770,Q9UBM7,P04062,Q10713,P21964,P16435,Q9NX62,Q13510,P04035,Q9NWW5,Q8WTV0 29 +Pore complex assembly 0.5065332847095455 1.2314684419660935 0.2181477126587014 1.0 0.5824471932042558 13 Q4KMQ2,Q9NQC3 2 +Autophagosome organization 0.4230998397518223 1.2309198485581834 0.2183528432289416 1.0 0.5825175434121048 26 Q7Z3C6,P04062,Q9Y371,P62820,Q9UMX0,P16615 6 +Adenosine metabolic process 0.7381101376721158 1.225522754614513 0.220378322058901 1.0 0.5861153259084553 2 P49902 1 +Regulation of er to golgi vesicle mediated transport 0.644051938133726 1.225393010551103 0.2204271791194654 1.0 0.5861153259084553 6 Q9NR31,Q9Y6B6,Q9P2W9 3 +Maintenance of location 0.3502273163664627 1.22281336734176 0.2214001954389295 1.0 0.5877366960134339 69 Q9BZF1,Q9Y679,P24390,O43292,O95202,P10253,Q9H6V9,P35610,Q9H4A6,P17900,O95674,Q14534,Q9UH99,O15258,P52789,O94901,Q9HD26,Q96HE7,O43731,P78417,P04062,P50416,Q8WTV0,Q00535 24 +Copi coated vesicle budding 0.7118166687485784 1.2219039257233089 0.2217439607327442 1.0 0.5881912236408352 4 P49755,Q9BVK6 2 +Regulated exocytosis 0.3786002550743759 1.2195851238598632 0.2226221885675054 1.0 0.5890477532333996 35 P49755,P61026,O43760,P09601,P49841,Q4J6C6,Q13636,Q9BRK5,P11279,Q7L0J3,P16615 11 +Regulation of defense response to virus 0.4778035506279637 1.218551757847239 0.2230143687814776 1.0 0.5895030015041933 15 O75844,O43657 2 +Olefinic compound metabolic process 0.4491844098866239 1.2154440150749837 0.2241967892464991 1.0 0.59103935641684 18 Q8NBN7,Q9HBH5,Q9H7Z7,Q8NCG7,Q8N2K0,P07099,Q9Y394 7 +Regulation of cardiac conduction 0.6415688570526242 1.2137639376919622 0.22483788089635 1.0 0.5916177026973196 6 P20020,Q6PI78,P16615 3 +Tetrapyrrole biosynthetic process 0.5032393712714451 1.2110731499903995 0.2258673707615184 1.0 0.5916177026973196 13 Q9P0S9,Q7KZN9,P22830,P36551,O00264 5 +Bone development 0.4117039862443224 1.2108824068469033 0.225940476201526 1.0 0.5916177026973196 28 Q7Z3C6,Q7RTS9,Q15904,O75844,P17302,Q9NX62,P16435,Q32P28,Q92896 9 +Ether metabolic process 0.5485834504703984 1.209364196094433 0.2265229576131253 1.0 0.5916177026973196 9 P07099,Q6PIU2,O15228,Q6IAN0 4 +Regulation of presynaptic cytosolic calcium ion concentration 0.8009389671361499 1.2090357327682852 0.2266491176914882 1.0 0.5916177026973196 3 P20020,P23634 2 +Response to oxidative stress 0.3240507152121915 1.2078931064827794 0.2270883815147284 1.0 0.5916177026973196 94 O43169,Q07820,Q99720,Q15392,Q13546,P39210,Q8N0U8,Q16134,P09601,P30519,P23246,Q15118,Q7Z2K6,P28074,Q86Y07,P03915,P18887,Q8IXJ6,Q6NUK1,Q15165,Q9UMX0,P16615,Q96HE7,P04062,O75306,Q8TED1,Q9NR28 27 +Axon ensheathment in central nervous system 0.7340425531914845 1.207246397573806 0.2273372669239837 1.0 0.5916177026973196 2 Q92542 1 +Positive regulation of mitochondrial calcium ion concentration 0.6775333028030975 1.2048804190485751 0.2282494687344911 1.0 0.5929333369341909 5 P51572,Q9BPX6,Q9Y3D6 3 +Posttranslational protein targeting to membrane translocation 0.7073345460756852 1.2027182205118558 0.229085380578518 1.0 0.5929727032347617 4 Q99442,P61619 2 +Limbic system development 0.434645929363079 1.1990007385809636 0.230527658416703 1.0 0.5950973552082597 22 P23634,P07196,Q00535,P18887,O14949,P49841,Q13144 7 +Protein localization to vacuole 0.4412935532275415 1.1983903541353542 0.2307650858766603 1.0 0.5950973552082597 20 Q9Y371,Q9NQC3 2 +Developmental maturation 0.3594855477906021 1.1974316474352835 0.231138354552115 1.0 0.5950973552082597 46 O75503,Q8N2A8,P04818,P51790,Q08J23,P04062,P07196,Q92543,Q86UL3,P17302,Q8IXJ6,Q9NZJ7,Q9Y2W6 13 +Negative regulation of calcium mediated signaling 0.706051021608753 1.1972245524064584 0.2312190424922233 1.0 0.5950973552082597 4 P23634,P49841 2 +Negative regulation of calcineurin mediated signaling 0.706051021608753 1.1972245524064584 0.2312190424922233 1.0 0.5950973552082597 4 P23634,P49841 2 +Regulation of morphogenesis of an epithelium 0.7979407795365935 1.1969326207846678 0.2313328182734784 1.0 0.5950973552082597 3 Q99623 1 +L serine transport 0.7976184490892204 1.1956317343878229 0.2318403018294548 1.0 0.5956611486463801 3 Q96QD8 1 +Positive regulation of necrotic cell death 0.6749233964756806 1.1932482150133894 0.2327721768662027 1.0 0.5973439844084316 5 Q7Z3C6,P00403 2 +Steroid hormone biosynthetic process 0.7049395369716509 1.1924674629826726 0.2330780013463851 1.0 0.5978917260062642 4 Q9UBM7,Q53GQ0 2 +Cerebellar cortex development 0.4735084475417381 1.1899620865392828 0.2340612939268029 1.0 0.5987618528834894 15 P04062,O14949 2 +Lung alveolus development 0.7036195543507833 1.1868183243812416 0.2352992892532097 1.0 0.5990782848335066 4 Q16706,P00813 2 +Acidic amino acid transport 0.4728854696587659 1.1858118327493443 0.2356966175419357 1.0 0.5992287197126618 15 Q9H936,O60831,O75915,Q9UJS0,Q8IWT6,Q8TDW0,P17302,Q15042,P05556,O75746,Q15041 11 +Organ growth 0.4291306322496164 1.1855201649007436 0.2358118466474559 1.0 0.5992287197126618 23 O75844,Q9NZJ7 2 +Quaternary ammonium group transport 0.795048492776891 1.1852619250422012 0.2359139026310046 1.0 0.5992287197126618 3 Q9HC21 1 +Nucleus organization 0.3497189125955585 1.183904743335062 0.23645077231714 1.0 0.5993629447979414 65 O14657,Q9NQC3,P50402,Q8NFH5,Q9H6H4,Q86XL3,O75844,Q6NUK4,Q8IXJ6,Q9BTX1,Q7Z3B4,O94901 12 +Layer formation in cerebral cortex 0.7027748942381455 1.1832036238858692 0.236728457121611 1.0 0.5993629447979414 4 Q96N66 1 +Photoreceptor cell maintenance 0.728410513141442 1.1819686662863078 0.2372181339274366 1.0 0.5993629447979414 2 P51790 1 +Negative regulation of cell development 0.4323918759501683 1.181513214435491 0.2373989070594171 1.0 0.5993908322343954 22 Q8N0X7,Q9NQC3,Q96G23 3 +Potassium ion import across plasma membrane 0.671630222961614 1.17857028723954 0.238569328925406 1.0 0.6010201233185005 5 Q9BXP2,P05023 2 +Potassium ion homeostasis 0.671630222961614 1.17857028723954 0.238569328925406 1.0 0.6010201233185005 5 Q9BXP2,P05023 2 +Nucleoside triphosphate metabolic process 0.3535180663834159 1.1759418811954787 0.2396181014017173 1.0 0.6016070828101511 50 Q7Z2Z2,P00846,P04818,P00403,P55263,P56385,O75964,O60313,P56134,P24539,P36542,Q8IWA4 12 +Erad pathway 0.3593135201126765 1.174657704988938 0.2401316869321159 1.0 0.6016158590094468 45 Q9UBU6,Q4ZIN3,Q8NBM4,Q96CS3,P51572,Q96A33,P27824,Q9GZP9,Q9UKV5,O60858,Q9UBV2,Q8TCJ2,Q6NTF9,Q9UMX0 14 +Positive regulation of chemokine c x c motif ligand 2 production 0.7265331664580768 1.1735507338618425 0.2405750243553726 1.0 0.6016158590094468 2 P14174 1 +Chemokine c x c motif ligand 2 production 0.7265331664580768 1.1735507338618425 0.2405750243553726 1.0 0.6016158590094468 2 P14174 1 +Positive regulation of dna ligation 0.7265331664580675 1.1735507338618008 0.2405750243553892 1.0 0.6016158590094468 2 P18887 1 +Regulation of dna ligation 0.7265331664580675 1.1735507338618008 0.2405750243553892 1.0 0.6016158590094468 2 P18887 1 +Transepithelial transport 0.6321776207937795 1.1697602390638706 0.2420974686702954 1.0 0.6035500408987792 6 P51798,P08183 2 +Insulin secretion 0.4235529638287876 1.1695435343863267 0.2421847120231968 1.0 0.6035500408987792 24 Q92543,P50416,Q9BRT2,P00367,Q08209,Q8N5M9,P40939,Q16836,O95563 9 +Positive regulation of muscle tissue development 0.669096724971854 1.1672784062633337 0.2430979561461987 1.0 0.6051269123762302 5 P41440 1 +Plasma membrane organization 0.3965321142185087 1.1639613288089463 0.2444396838093934 1.0 0.6063741434857232 30 P41440,Q7Z3C6,Q9Y371,Q16739,Q4KMQ2,Q9H1P3,P16615 7 +Regulation of membrane permeability 0.4365527644662591 1.1628239592838794 0.2449009341276335 1.0 0.6064137698896387 20 Q969V5,P05141,P12235,P45880,P52789 5 +Sensory perception 0.3617691952128082 1.162760472126819 0.2449266987780463 1.0 0.6064137698896387 43 P50897,Q00169,O60313,Q13432,Q9Y6M9,P62072,Q96HR9,Q14108,Q9H6K4,Q9BRK0,Q9NWW5,Q9H5K3 12 +Aminoglycan catabolic process 0.667379098934226 1.1596231528206935 0.2462022702464079 1.0 0.6084107797040763 5 P04066,P08236,P15586 3 +Glycosaminoglycan catabolic process 0.667379098934226 1.1596231528206935 0.2462022702464079 1.0 0.6084107797040763 5 P04066,P08236,P15586 3 +Phosphatidylcholine metabolic process 0.4686670031081497 1.157686655755217 0.2469919315238873 1.0 0.6089644879324185 15 Q8WWI5,Q86UL3,Q8NF37,P35790,Q9Y6K0,Q96N66,Q8WTV0 7 +Sodium ion transport 0.4099705210291895 1.1571051694741767 0.2472293948944064 1.0 0.6093178384450109 27 P23634,Q9H2J7,P05023,Q9Y6M7,Q96PU5,Q4KMQ2,Q96QD8 7 +Vesicle organization 0.3165060787258463 1.155203163278082 0.2480072396572628 1.0 0.6105374115868409 97 Q9BRG1,Q9BVK6,Q9UNK0,O60499,Q13190,Q9BTU6,Q9BSR8,P51790,O75340,Q14108,Q9H4A6,O15027,O14966,P49755,O14653,Q92543,P62820,O75396,Q15363,Q9Y6B6,O15400,Q86Y82,P31751,Q12770,O14964,Q9NR31,Q9HCU5,O95249,Q5JRA6 29 +Regulation of receptor signaling pathway via stat 0.5381921064940611 1.1522592040732818 0.2492145756681507 1.0 0.6123450014139225 9 Q9H490,Q9NX40,Q00535 3 +Dna methylation involved in gamete generation 0.7867351880829546 1.1517479071055108 0.2494246797690613 1.0 0.6124428382355571 3 Q8N2A8 1 +Positive regulation of triglyceride metabolic process 0.786339665139242 1.150154687426728 0.2500801654380988 1.0 0.6130753146649152 3 Q8NCG7 1 +Leukotriene biosynthetic process 0.7859154929577257 1.1484462046265038 0.2507844087663005 1.0 0.6142947122736367 3 Q99735,P09960 2 +Oligodendrocyte development 0.5868016806235735 1.1480274450945662 0.2509572341241495 1.0 0.6142947122736367 7 P18074,Q92542,P49770,Q13144 4 +Negative regulation of toll like receptor signaling pathway 0.7851767641341694 1.1454710991898414 0.252014060724326 1.0 0.6155935637889615 3 Q9NPR9 1 +Regulation of transmembrane transport 0.3398639995492898 1.1428595194779552 0.2530969220349977 1.0 0.617174465364908 74 Q9BZF1,Q13586,Q9BVC6,P27105,Q4KMQ2,O75298,Q15041,P08183,O75844,P17302,P21796,P23634,Q99623,O75323,Q96PU5,P52789,Q8TAD4,Q9UMX0,Q9HD26,P31751,P78417,Q00535 22 +Regulation of sulfur metabolic process 0.7844199198747271 1.1424235057255168 0.2532780253413467 1.0 0.617174465364908 3 Q15118 1 +Phosphatidylinositol acyl chain remodeling 0.7840375586854303 1.1408840307741792 0.253918185703363 1.0 0.6182688103356528 3 Q96N66,Q92604 2 +Adult locomotory behavior 0.4661115484281808 1.1406314773248087 0.2540233125231073 1.0 0.6182921694808388 15 P50897,O15118,O75844,Q8N2K0 4 +Negative regulation of canonical wnt signaling pathway 0.4385024606752027 1.1377948884954234 0.2552061398626442 1.0 0.6202193982266042 18 Q13641,Q9UKV5,P50402,Q8NBM4 4 +Activation of store operated calcium channel activity 0.7183979974968657 1.1371252580351587 0.2554859264017501 1.0 0.6202193982266042 2 Q13586 1 +Positive regulation of store operated calcium channel activity 0.7183979974968657 1.1371252580351587 0.2554859264017501 1.0 0.6202193982266042 2 Q13586 1 +Ventricular system development 0.5441800730588273 1.13266261245677 0.2573559639938221 1.0 0.6225238625726631 8 Q96N66 1 +Ganglioside metabolic process 0.6906423023716369 1.131307481474422 0.2579256965153367 1.0 0.6225238625726631 4 P17900 1 +Cytoplasm organization 0.7811317435004945 1.1291886979168668 0.2588182404478099 1.0 0.6225238625726631 3 Q8N2A8 1 +Heparan sulfate proteoglycan metabolic process 0.6605400635698784 1.129146963403912 0.2588358427040231 1.0 0.6225238625726631 5 Q7LGA3 1 +Heparan sulfate proteoglycan biosynthetic process 0.6605400635698784 1.129146963403912 0.2588358427040231 1.0 0.6225238625726631 5 Q7LGA3 1 +Positive regulation of fatty acid metabolic process 0.6901047306980567 1.1290094813754823 0.2588938340062485 1.0 0.6225238625726631 4 P31751,Q92604 2 +Signal release 0.3490740300809121 1.1289210907319434 0.2589311228229221 1.0 0.6225238625726631 54 P50897,P14174,P49841,P62820,Q92543,Q00535,P50416,Q4J6C6,P00367,P17302,Q8N5M9,P40939,Q16836,O95563,Q7L0J3,P16615 16 +Outer mitochondrial membrane organization 0.6603467915823429 1.1282858554951711 0.2591992150719564 1.0 0.6225238625726631 5 Q9NS69 1 +Muscle hypertrophy in response to stress 0.6896689634123077 1.127146781855326 0.2596804267386323 1.0 0.6233871371856189 4 P23634,P16615 2 +Appendage development 0.4896032944706501 1.1264340489547282 0.2599818414423402 1.0 0.6238793021189567 13 P42892,Q9C0E8,P17302,Q9NX62,Q12797 5 +Oocyte differentiation 0.5428061945828822 1.125298068212046 0.2604627480642811 1.0 0.624728330880086 8 Q8N2A8,Q8IXJ6 2 +Dedifferentiation 0.7155819774718344 1.1245381947060713 0.2607847766227213 1.0 0.624728330880086 2 Q14103 1 +Protein geranylgeranylation 0.7798429433724969 1.1240039689590071 0.2610113421971187 1.0 0.624728330880086 3 P53611 1 +Nuclear pore complex assembly 0.5326816557274058 1.1219333212457292 0.2618907917004525 1.0 0.6261386050555332 9 Q9NQC3 1 +Positive regulation of autophagy of mitochondrion 0.5815302956144287 1.1216352554155669 0.2620175551848045 1.0 0.6262103460694441 7 P27544,P21796,P12235 3 +Circulatory system process 0.3389631467634996 1.12005693084766 0.2626895024446387 1.0 0.6271978548455809 73 Q9UIQ6,Q93063,Q9HB40,Q6PI78,P41440,Q6P179,Q8WWI5,P08183,P09601,O75844,P17302,Q9NZ08,P20020,P30825,P23634,Q96PU5,P16615,P42892,Q96QD8,P78417,P05023,P42785 22 +Negative regulation of immune effector process 0.54131801942045 1.1173194612699413 0.263857757310634 1.0 0.627553786403249 8 P09601,P55061 2 +Regulation of short term neuronal synaptic plasticity 0.7137046307884801 1.1161536182348293 0.2643563842259091 1.0 0.627553786403249 2 Q96A49 1 +Positive regulation of neurotransmitter secretion 0.71370463078848 1.1161536182348282 0.2643563842259095 1.0 0.627553786403249 2 Q00535 1 +Response to gamma radiation 0.4624323388535247 1.1160550502994475 0.26439857114567 1.0 0.627553786403249 15 O60858 1 +Cytosolic calcium ion transport 0.4051088836619759 1.115803700804823 0.2645061693373762 1.0 0.627553786403249 27 P23634,P78417,P55061,Q9BPX6,O95202,P21796,Q8WWC4,P20020,Q9Y4W6,P16615 10 +Regulation of perk mediated unfolded protein response 0.7127659574468337 1.111963448755945 0.2661538662270044 1.0 0.627553786403249 2 P57088 1 +Positive regulation of ire1 mediated unfolded protein response 0.7127659574468337 1.111963448755945 0.2661538662270044 1.0 0.627553786403249 2 P57088 1 +Positive regulation of endoplasmic reticulum unfolded protein response 0.7127659574468337 1.111963448755945 0.2661538662270044 1.0 0.627553786403249 2 P57088 1 +Positive regulation of amino acid transport 0.6861086565772059 1.111932070464899 0.2661673584173236 1.0 0.627553786403249 4 Q15042,Q15041 2 +Response to activity 0.4990908147529511 1.1102125118322654 0.2669074624685721 1.0 0.628438483087108 12 P40939,Q9UDX5,Q16836 3 +Regulation of fatty acid oxidation 0.7762128325508523 1.10940890396113 0.2672538229815537 1.0 0.628438483087108 3 P50416,P31751 2 +Regulation of neurotransmitter levels 0.3852970426115713 1.1087041066426349 0.267557849751366 1.0 0.628438483087108 31 P50897,P21964,Q8NCG7,Q7L0J3,P16615 5 +Copper ion homeostasis 0.6852109976430232 1.108097171078783 0.2678198525781803 1.0 0.6287015182756558 4 O75880,O43819 2 +Protein localization to plasma membrane 0.3358534203175915 1.102304321777888 0.270329391123703 1.0 0.632070743985768 75 Q9BXS4,Q15904,Q9UNK0,Q6IQ22,P41440,Q8N2H4,Q4J6C6,Q9H4A6,P98194,P23634,P35613,Q13641,Q15363,O15258,O15400,Q9HD26,P61026,P31751,Q13636,O00264 20 +Multicellular organism growth 0.4031814889105486 1.0994077344925952 0.2715902586158973 1.0 0.6339529793451413 27 P11802,Q9HCL2,O75844,Q86UL3,O15020,Q15363,O95470 7 +Membrane repolarization 0.5285880641450464 1.0993897974178328 0.271598079046448 1.0 0.6339529793451413 9 Q96PU5,O75844,P05023 3 +Cerebellar cortex formation 0.6170416188115726 1.0988067686153915 0.271852359224277 1.0 0.6342568381036484 6 P04062 1 +Collagen biosynthetic process 0.6824150328756244 1.0961558464567478 0.2730105784332743 1.0 0.6363479735120559 4 P08670 1 +Positive regulation of chemokine production 0.6162812227809593 1.0952424929917062 0.2734104139568747 1.0 0.6369734338116966 6 P09601,P14174 2 +Positive regulation of ligase activity 0.7083854818523141 1.092428909624763 0.2746446217879297 1.0 0.6382805583268392 2 P18887 1 +Regulation of ligase activity 0.7083854818523141 1.092428909624763 0.2746446217879297 1.0 0.6382805583268392 2 P18887 1 +Response to redox state 0.7077596996245568 1.0896409970191367 0.275871316369668 1.0 0.6382805583268392 2 Q8IXJ6 1 +Organophosphate metabolic process 0.2927563584557562 1.0873954073897525 0.2768620999791595 1.0 0.6382805583268392 259 P49902,P43490,Q9NTJ5,Q9HCL2,O43292,Q9BRR6,Q8NF37,Q9Y6K0,O15228,Q96N66,P40939,Q8N2K0,Q5H8A4,P50897,P00403,P35610,O60313,O14735,Q86YN1,P24539,Q53GQ0,Q9BVG9,Q9NZ01,O95674,Q9H490,Q96JX3,O75964,P56385,Q9UG56,Q9NPH0,Q6Y1H2,P37268,P52789,Q92604,Q8WVC6,P00846,Q8IWA4,P56134,Q10713,Q8TB61,Q86UL3,P36542,Q9NX62,P04035,Q8WTV0 45 +Sensory perception of light stimulus 0.4232957849843455 1.0854038897076663 0.2777428103842603 1.0 0.6382805583268392 21 P50897,Q00169,O60313,Q13432,Q96HR9,Q9H6K4,Q9NWW5 7 +Taurine transport 0.706195244055063 1.082674333709742 0.2789530002507039 1.0 0.6382805583268392 2 Q8TDW0 1 +Glial cell development 0.4304861944717564 1.079335356585996 0.2804382567702239 1.0 0.6408885585511614 18 P31751,Q92542,O43175,P49770,P18074,Q8IXJ6,P08670,Q9NR50,Q00535,Q13144 10 +Negative regulation of organic acid transport 0.768388106416279 1.077996277059352 0.2810354175702327 1.0 0.6413795472368703 3 P31751,O75915 2 +Response to abiotic stimulus 0.2913731607743535 1.075589538482757 0.2821108681803947 1.0 0.6433479700012386 211 Q92544,Q9UNS2,Q9BVC6,Q9Y487,Q15904,Q96A26,O60858,Q9BPX6,O95202,Q8N2K0,Q9BRK5,Q13144,Q8N511,Q8NBN7,P08183,P00403,P09601,Q70UQ0,P30519,O75844,Q15118,O75340,P17302,Q96HR9,P20020,P23634,P51798,Q99623,P22830,P03915,P18887,Q14011,Q8IXJ6,P52789,P49841,Q96QD8,Q9UMX0,P31751,Q96HE7,Q12770,P00846,P04062,P55061,Q13432,O75306,P27544,Q9Y4P3,P04035 48 +Positive regulation of regulated secretory pathway 0.6772994487443835 1.074322236656941 0.2826782820410556 1.0 0.6442813339218428 4 P11279 1 +Necrotic cell death 0.4294142466793827 1.0736870669478185 0.2829629598015164 1.0 0.6446097415823352 17 P12235,Q13510,P00403 3 +Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.5328386305887317 1.0718366874170728 0.2837933915090174 1.0 0.6455749925985025 8 P09601 1 +Microtubule anchoring at microtubule organizing center 0.6765646956412894 1.0711879772261124 0.2840849163968688 1.0 0.6455749925985025 4 P49841 1 +Microtubule anchoring at centrosome 0.6765646956412894 1.0711879772261124 0.2840849163968688 1.0 0.6455749925985025 4 P49841 1 +Collagen catabolic process 0.7021276595744942 1.0645826754875671 0.2870648230861632 1.0 0.6496096276272975 2 Q9UBG0 1 +Mesodermal cell differentiation 0.7021276595744728 1.064582675487471 0.2870648230862067 1.0 0.6496096276272975 2 P17302 1 +Cellular defense response 0.7021276595744657 1.0645826754874397 0.2870648230862209 1.0 0.6496096276272975 2 Q08380 1 +Cell cell adhesion mediated by integrin 0.7021276595744619 1.064582675487423 0.2870648230862285 1.0 0.6496096276272975 2 P00813 1 +Negative regulation of production of molecular mediator of immune response 0.7648380572050868 1.0637680192459398 0.2874338022961282 1.0 0.6502172556660406 3 P09601 1 +Positive regulation of cell cell adhesion 0.3801079646668907 1.0608454442523496 0.2887601458806663 1.0 0.6512486577917985 31 Q11206,Q9HCL2,Q08722,P30825 4 +Cytosolic transport 0.3416309770661673 1.0584266271398477 0.2898609853441842 1.0 0.6531964822937188 60 O75503,Q8N2H4,O15498,Q9BVK6,O60499,Q9UNK0,A4D1P6,O95249,Q13190,P49257,O15260,P11279,O14966 13 +Gliogenesis 0.3430928707849987 1.057715967302073 0.2901849534597833 1.0 0.6534714748753367 52 Q7Z4L5,P31751,Q9NQC3,P04062,Q96G23,Q8IXJ6,P08670,Q96N66,O94901,Q13144 10 +Regulation of anion channel activity 0.7630711171860611 1.056692252520814 0.2906520619857693 1.0 0.6536205648090856 3 P08183 1 +Cellular response to nutrient 0.6442143850623707 1.0564643506863696 0.2907561196052777 1.0 0.6536205648090856 5 P09601,Q8TB36 2 +Adipose tissue development 0.511166035320643 1.0555841092463742 0.2911582640331493 1.0 0.6536212019074383 10 Q8N0X7,O15173,P35610,P43490 4 +Srp dependent cotranslational protein targeting to membrane 0.5197417343565847 1.050641948242185 0.2934230673480229 1.0 0.6562287148036514 9 Q15629,P61619 2 +Antigen processing and presentation 0.4120618210506224 1.0502244114299326 0.2936149485477153 1.0 0.6562287148036514 23 Q6P179,P61026,Q9UIQ6,P04062,Q03519,Q9Y6B6,Q9NZ08,P10321,P04439 9 +Retinal rod cell development 0.6986858573216459 1.0493001595880111 0.294039992599004 1.0 0.6562287148036514 2 Q15555 1 +Retinal rod cell differentiation 0.6986858573216459 1.0493001595880111 0.294039992599004 1.0 0.6562287148036514 2 Q15555 1 +Camera type eye photoreceptor cell differentiation 0.6986858573216459 1.0493001595880111 0.294039992599004 1.0 0.6562287148036514 2 Q15555 1 +Cardiolipin metabolic process 0.5277953873484718 1.044773721850113 0.2961275628091007 1.0 0.6588671123897678 8 P40939,Q99623,Q6UWP7,Q8WUK0 4 +Cellular macromolecule localization 0.2944938070320528 1.044738011942249 0.2961440713754379 1.0 0.6588671123897678 561 Q9NQC3,Q99595,P43307,P24390,Q15904,Q9UNK0,Q8N4H5,Q6IQ22,Q13190,Q7Z3B4,O75298,P46379,Q8N4V1,P13473,Q7Z434,Q4J6C6,Q9NS69,Q3ZCQ8,P56589,Q8N8Q8,P17302,Q9Y276,Q9H4A6,Q9Y282,Q15629,P23634,O60725,Q9Y5M8,P57105,Q13561,Q9P2W9,Q9Y6Y8,Q15070,Q9UH99,P49841,Q9HD26,Q9Y5J6,Q7Z5K2,O14773,O14925,O43731,Q10713,Q14012,Q8NFG4,Q8NC56,Q5JRA6,O00264,Q13636,Q9Y6C9,Q15005,Q00535,Q969Q5,Q9BZF1,Q9Y679,Q9BXS4,P27105,Q9NPA0,P55786,Q7L2J0,O60499,Q9BRK0,Q15006,Q96JB2,Q86YV9,P40855,Q9Y371,Q96A33,Q9HD20,Q8N2H4,Q9P0J0,P62072,Q9HD45,Q14108,Q9H300,Q7Z4L5,Q9H490,Q13641,Q96PU5,Q9H1Z9,O15258,P52789,O94901,O14657,Q9Y3A6,Q9NR31,P10619,Q9UBV2,Q8WWC4,Q92544,P50402,Q8NBM4,O43292,Q9BVK6,Q9Y3B3,Q15041,P41440,P51572,O15118,O75340,P98194,P11279,O14966,P49755,P62820,Q9GZP9,P35613,O43681,Q7Z3C6,P61026,O75381,O96008,O43615,Q16880,P49257,O15260,Q8NFH5,Q9Y512,Q8NBU5,Q96CS3,Q8TB36,Q14789,O15504,Q16181,Q9H0U4,Q99442,Q8IZ07,P61619,Q99623,Q15363,Q92643,A0AVF1,O15400,Q99729,P31751,Q9UGP8,Q53H12,P49354 137 +Regulation of mitochondrial membrane permeability involved in apoptotic process 0.4879447137919804 1.0431193261979697 0.2968930309085056 1.0 0.6598529175961018 12 P45880 1 +Bone growth 0.7592606318347339 1.041447312874874 0.2976679938108724 1.0 0.6602659324205424 3 O75844 1 +Growth plate cartilage development 0.7592606318347339 1.041447312874874 0.2976679938108724 1.0 0.6602659324205424 3 O75844 1 +Vesicle docking 0.424785998225187 1.0401684145348309 0.2982616631302353 1.0 0.6613050646724504 17 P61026,O60499,Q9UNK0,Q6IQ22,O15400,O15498 6 +Positive regulation of er associated ubiquitin dependent protein catabolic process 0.7584599584530456 1.0382465652845272 0.2991552787335672 1.0 0.6618872006440307 3 P51572 1 +Phosphate ion transmembrane transport 0.7583724569639717 1.0378968277384824 0.2993180905818304 1.0 0.6618872006440307 3 Q9UBX3,Q02978 2 +Phosphate ion transport 0.7583724569639717 1.0378968277384824 0.2993180905818304 1.0 0.6618872006440307 3 Q9UBX3,Q02978 2 +Srp dependent cotranslational protein targeting to membrane translocation 0.6687409595480989 1.0378446779309831 0.2993423727263717 1.0 0.6618872006440307 4 Q15629 1 +Long chain fatty acid metabolic process 0.4136383474955131 1.0354569159931717 0.3004555771530475 1.0 0.6636684284418168 22 P28288,O14975,P50416,Q9H7Z7,P23786,Q8NCG7,O95864,Q8N2K0,P07099 9 +Retinol metabolic process 0.5640327544145454 1.0340049829581817 0.3011338337377274 1.0 0.6645619181810936 7 Q9Y394,Q9HBH5,Q8NBN7 3 +Regulation of mitotic centrosome separation 0.6949311639549374 1.032657126644633 0.301764383962924 1.0 0.6651972387629579 2 P52732 1 +Regulation of receptor mediated endocytosis 0.4162208655738125 1.0311412388751164 0.3024745914940396 1.0 0.6662522090987071 21 P41440,P50897,Q13432,Q8NBU5 4 +Negative regulation of oxidoreductase activity 0.6668973384274226 1.0299965139867986 0.3030116420101842 1.0 0.6666792472746338 4 Q15070 1 +Homeostatic process 0.2874035353269453 1.0291571013386418 0.3034058571760749 1.0 0.6667717173662333 293 Q92544,P14174,Q13586,Q9NQC3,O00767,Q9P0S9,Q07820,Q9UIQ6,Q9Y487,Q15904,Q9HCL2,Q9NX40,Q9BPX6,Q15067,Q8NF37,Q9Y6N1,Q9BWH2,O95202,Q16891,P40939,Q4KMQ2,Q7L0J3,P50897,O75503,Q8N511,P39210,P51790,P09601,P13473,Q96A33,P30519,Q9HD20,P51572,P35610,O15118,Q9P035,P17302,Q9UM00,P20020,Q16836,P98194,Q9Y4W6,P23634,Q658P3,O15254,O75027,Q96PU5,Q15043,P23786,Q9H9B4,P52789,Q8TAD4,O95563,P16615,Q93050,Q96HE7,O14773,P78417,P04062,P55061,Q16739,P05141,Q9Y6M7,P42785,P05023,O43819,Q96TC7,Q8WWC4,Q8NFG4,O15260,Q9Y6C9,Q9NWW5,Q8WTV0,Q8N5M9,Q00535,O75880 76 +Positive regulation of myotube differentiation 0.6939924906132604 1.0285012839284433 0.3037140871912231 1.0 0.666996122260468 2 P42345 1 +Positive regulation of myoblast differentiation 0.6939924906132602 1.0285012839284424 0.3037140871912236 1.0 0.666996122260468 2 Q8IWT6 1 +Embryonic heart tube development 0.6015103982955512 1.0260438010388604 0.3048709383935506 1.0 0.6681763336549473 6 P42892,Q15363 2 +Positive regulation of t cell proliferation 0.5053659661566104 1.0227165408962562 0.3064418883247506 1.0 0.6709377203104824 10 Q9HCL2 1 +Mitochondrial outer membrane permeabilization 0.4956256611594823 1.0219565808449442 0.3068014509972716 1.0 0.6712048105106079 11 P45880 1 +Regulation of coagulation 0.6646558644768429 1.020459854945459 0.3075104192918227 1.0 0.6712048105106079 4 Q11206 1 +Regulation of cartilage development 0.6360773776131555 1.020301480389166 0.3075855014631092 1.0 0.6712048105106079 5 P16435,Q9C0E8 2 +Regulation of chondrocyte differentiation 0.6360773776131555 1.020301480389166 0.3075855014631092 1.0 0.6712048105106079 5 P16435,Q9C0E8 2 +Anatomical structure maturation 0.3672814834546846 1.018692612818491 0.3083489207281471 1.0 0.6714785380055748 33 O75503,Q8N2A8,P04818,P04062,Q86UL3,P17302,Q8IXJ6,Q9NZJ7,Q9Y2W6 9 +Pattern recognition receptor signaling pathway 0.384841323220602 1.016391428689287 0.3094430256460272 1.0 0.6725485382832812 29 P41440,Q9NPR9,Q9NQC3,O43657,Q99623,Q9UMX0 6 +Regulation of phospholipase c activity 0.6911764705882577 1.016046049774337 0.3096074582038128 1.0 0.6725485382832812 2 Q99623 1 +Activation of phospholipase c activity 0.6911764705882577 1.016046049774337 0.3096074582038128 1.0 0.6725485382832812 2 Q99623 1 +Activation of protein kinase c activity 0.6911764705882577 1.016046049774337 0.3096074582038128 1.0 0.6725485382832812 2 Q99623 1 +Positive regulation of interleukin 17 production 0.6911764705882288 1.0160460497742103 0.3096074582038732 1.0 0.6725485382832812 2 Q14699 1 +Organic hydroxy compound catabolic process 0.4834286212623356 1.0159113414802226 0.3096716075531796 1.0 0.6725485382832812 12 Q10713,Q9NX62,P21964 3 +Sodium ion transmembrane transport 0.4074871852540413 1.0138437151543558 0.3106573321280663 1.0 0.6728807885529043 23 P23634,Q9H2J7,P05023,Q9Y6M7,Q96PU5,Q4KMQ2 6 +Cardiolipin biosynthetic process 0.6905506883604664 1.0132807842676377 0.3109260632390778 1.0 0.6730145422352212 2 Q8WUK0 1 +Positive regulation of amine transport 0.6342902338410377 1.0123668525130023 0.3113626811673566 1.0 0.673509115145432 5 Q15042,Q15041 2 +Embryonic appendage morphogenesis 0.5034657831279813 1.0119471998361156 0.3115632996752764 1.0 0.6735872295920287 10 P42892,Q9NX62,Q9C0E8 3 +Gland development 0.3364168978633571 1.0091462998455538 0.3129044759933879 1.0 0.6752643443245103 63 P31751,Q9UNS2,Q9NQC3,Q9UGP8,P04818,P00403,P09601,P35610,Q99623,O75844,P50416,Q86UL3,P07602,P17302,Q9NZJ7,Q13505,P52789 17 +Lipoprotein catabolic process 0.6335085049848115 1.0088971051960456 0.3130239836648125 1.0 0.6752970740928889 5 P50897 1 +Regulation of post translational protein modification 0.6617362358759342 1.008046855514175 0.313431968836571 1.0 0.6755156099841951 4 Q32P28,O75718 2 +Endothelial cell proliferation 0.4207076858205445 1.0078610917149398 0.3135211526011026 1.0 0.6755156099841951 18 P09601,P57105,Q8WTV0 3 +Appendage morphogenesis 0.4930889729589324 1.0071641278847163 0.3138559084089114 1.0 0.6755156099841951 11 P42892,P17302,Q9NX62,Q9C0E8 4 +Sodium ion homeostasis 0.5206620383709376 1.0064921401926468 0.3141788906132734 1.0 0.6755304786328138 8 Q96PU5,P05023 2 +T cell differentiation 0.3922573075616391 1.0062811899283708 0.3142803261995368 1.0 0.6755304786328138 27 O96005,P24390 2 +Positive regulation of leukocyte cell cell adhesion 0.4032256756142891 1.005509873650407 0.3146513975058747 1.0 0.6761035340830083 24 Q11206,Q9HCL2,P30825 3 +Regulation of cytoplasmic mrna processing body assembly 0.7498427447041982 1.0038598339428069 0.3154461791794571 1.0 0.6771248495542465 3 Q9HBH5 1 +Phosphatidylserine metabolic process 0.5964554721384898 1.0023896085722777 0.3161554589347768 1.0 0.6773115293697038 6 Q8N2K0,Q9BVG9 2 +Response to arsenic containing substance 0.4575085644986837 1.0006629068249504 0.3169898061063985 1.0 0.6784252728573449 14 P09601,P07196,Q96QD8,P78417 4 +Positive regulation of torc1 signaling 0.6593613024420717 0.9979576097376628 0.3182999145117828 1.0 0.6796559045596366 4 Q9P2J5,Q8NFG4,Q9NWS0 3 +Response to zinc ion 0.6589972910618425 0.9964118666085752 0.3190500696297991 1.0 0.6801154856868619 4 Q8TAD4 1 +Hormone catabolic process 0.7476475960608644 0.9951192564514058 0.3196782660890431 1.0 0.6801485641775347 3 P42892 1 +Protein trimerization 0.6575036561273087 0.9900711654153757 0.3221393359653319 1.0 0.6830180841496677 4 Q99720 1 +Perk mediated unfolded protein response 0.6572429258438806 0.9889646436089032 0.3226804406008885 1.0 0.6830180841496677 4 P57088 1 +Endoplasmic reticulum unfolded protein response 0.4106937691852475 0.9886906446330928 0.32281452144883 1.0 0.6830180841496677 21 Q96HE7,P57088,Q9UKV5,Q9GZP9,Q7Z2K6,Q15363,Q9Y4P3,Q6NTF9 8 +Cellular response to mineralocorticoid stimulus 0.745827509217557 0.9878783822928828 0.3232122138614963 1.0 0.6830180841496677 3 P20020 1 +Regulation of response to osmotic stress 0.5932898732405094 0.9875867503094836 0.3233550779163257 1.0 0.6830180841496677 6 Q9BPX6,P08183 2 +Fatty acid alpha oxidation 0.6563191700755144 0.9850450591535465 0.3246019383976497 1.0 0.6843074088956316 4 A1L0T0,O43808 2 +Peroxisomal transport 0.5165048060910068 0.9841860510132762 0.3250240429970288 1.0 0.6845283456806933 8 P40855,P28288,O75381,P56589,O14678 5 +Positive regulation of cold induced thermogenesis 0.4887636736975901 0.981940114693146 0.3261293516624735 1.0 0.685441049633162 11 P40939,Q16836,P23786,O00767 4 +Negative regulation of response to external stimulus 0.3398469105452828 0.9808721635659604 0.3266557861523016 1.0 0.685738819709289 46 P80303,Q969V5,O43657,Q96G23 4 +T cell activation 0.3362212470997079 0.9808669839631824 0.3266583407236925 1.0 0.685738819709289 55 P04062,P24390,Q9HCL2,Q08722,O96005,P30825 6 +T cell mediated cytotoxicity 0.5157042946637531 0.9798915128232262 0.3271396728317657 1.0 0.6859421436075732 8 O15400,P04439,P15151 3 +Protein localization to golgi apparatus 0.4881907407003342 0.9785989675153888 0.327778169645029 1.0 0.6859421436075732 11 Q8N2H4,Q9H4A6 2 +Protein transport within lipid bilayer 0.7431828835801091 0.9773677653429276 0.3283871154412154 1.0 0.6864733240101895 3 Q9BRK0 1 +Response to xenobiotic stimulus 0.334058495617669 0.9755929812027158 0.3292662041079925 1.0 0.6872884063572138 62 O43169,P11802,P08183,P04818,P09601,P07099,P78417,P05023,P50416,P27544,O15118,Q16836,P16435,O15228,P40939,Q6PIU2 16 +Regulation of secretion 0.3106901503136095 0.9753842615229606 0.3293696875613066 1.0 0.6872884063572138 92 P14174,Q6IQ22,P40939,Q7L0J3,P09601,Q16850,Q4J6C6,P17302,Q9H4A6,Q16836,P11279,P49755,Q96KC8,P00367,Q32P28,O95563,P49841,P16615,P61026,P50416,P04035,Q8N5M9,Q00535 23 +Positive regulation of adenylate cyclase activity 0.6814768460575763 0.9732964092370496 0.3304060065668019 1.0 0.6880269222974573 2 Q13586 1 +Glutamate secretion neurotransmission 0.6814768460575653 0.9732964092370014 0.3304060065668259 1.0 0.6880269222974573 2 Q15042 1 +Fibroblast proliferation 0.4649633684632019 0.9729386233182358 0.3305838075072138 1.0 0.6881757485322252 13 P11802,P14174,O75844,P50402 4 +Establishment of protein localization to plasma membrane 0.3955719044263187 0.9708854946508956 0.3316053021811926 1.0 0.6895191423670531 25 P61026,Q15904,Q8N2H4,Q4J6C6,Q9H4A6,Q13636,P98194,Q9HD26 8 +Cellular copper ion homeostasis 0.7414710485132876 0.9705712327039474 0.3317618370412551 1.0 0.6895191423670531 3 O75880,O43819 2 +Bleb assembly 0.7412679242346301 0.9697651308710952 0.3321635772260942 1.0 0.6898211621788111 3 Q4KMQ2 1 +Nls bearing protein import into nucleus 0.5134397569567282 0.9677444553494144 0.3331720101691979 1.0 0.6911630456237654 8 Q7Z3B4 1 +Chemokine c c motif ligand 5 production 0.6520203867160785 0.966821413729198 0.3336333176619668 1.0 0.6912811243918286 4 Q969V5 1 +Cellular potassium ion homeostasis 0.6511962932920372 0.9633311096529968 0.3353813860103081 1.0 0.693035865344417 4 P05023 1 +Negative regulation of intrinsic apoptotic signaling pathway 0.3526597725862199 0.9621427493833018 0.3359779026618696 1.0 0.6936041422735632 35 Q8N2F6,P55061,Q9P0J0,P45880,Q9H300 5 +Hydrogen peroxide biosynthetic process 0.7390887176930231 0.9611219095710312 0.3364908746237218 1.0 0.6937779358282026 3 P00403 1 +Retinal metabolic process 0.7389671361502093 0.9606399623727144 0.33673322805512 1.0 0.6938355466325173 3 Q8TC12,Q8NBN7 2 +Adult behavior 0.411469797476059 0.9556655248591364 0.339241245364565 1.0 0.6960906001828296 19 P50897,P51790,O75844,O15020,O15118,Q8N2K0 6 +Response to fatty acid 0.4839270903138039 0.9537369269008468 0.3402168232414948 1.0 0.6973778076307554 11 P11802,O00767,O15228 3 +Leukocyte cell cell adhesion 0.349817480700503 0.9530922285275352 0.3405433433505 1.0 0.6973778076307554 37 Q11206,Q9HCL2,P30825,Q9H4A6 4 +Regulation of osteoclast differentiation 0.6486396867542839 0.9525100390950172 0.3408383770324596 1.0 0.6973778076307554 4 P42345,Q9BRX8 2 +Positive regulation of neurotransmitter transport 0.6484032561051891 0.951509872043725 0.3413456095343186 1.0 0.6973778076307554 4 P05556,Q15042,Q00535 3 +Integrated stress response signaling 0.6204080129676832 0.9508558854866916 0.3416775385067208 1.0 0.6978027861203839 5 Q15363,P57088,P18031 3 +Meiotic cytokinesis 0.6761576971213946 0.9499624596974096 0.3421313278648115 1.0 0.698255236936598 2 P61160 1 +Fatty acid transport 0.4127735231796904 0.949782566523816 0.3422227459151559 1.0 0.698255236936598 18 P31751,P14174,O43808,P28288,O14975,Q9Y3D6,P50416,P23786,O14678 9 +Regulation of cardiac muscle cell proliferation 0.6758448060075023 0.9485924753221064 0.3428279195338035 1.0 0.6986051592414081 2 Q16539 1 +Positive regulation of cardiac muscle cell proliferation 0.6758448060075023 0.9485924753221064 0.3428279195338035 1.0 0.6986051592414081 2 Q16539 1 +Skeletal system development 0.3335899665535743 0.9483840814831418 0.3429339602765688 1.0 0.6986051592414081 53 Q7Z3C6,Q7RTS9,Q93063,Q9C0E8,P04818,P51812,Q92543,Q15904,O75844,P17302,Q15043,Q9NX62,Q32P28,P16435,O95470,Q92896 16 +Cerebellar purkinje cell layer morphogenesis 0.619770939960306 0.948039170895715 0.3431095133165565 1.0 0.698742847761093 5 P04062,Q7Z4L5 2 +Icosanoid biosynthetic process 0.4826082740954148 0.9460478745830396 0.3441241684181899 1.0 0.6991766213117795 11 Q99735,Q8NCG7,P09960 3 +Central nervous system maturation 0.6742803504380404 0.9417470397482374 0.3463221654596466 1.0 0.7004602809379403 2 P48444 1 +Cartilage development involved in endochondral bone morphogenesis 0.6456988817601376 0.9400764547936814 0.3471783451666637 1.0 0.7010727768856934 4 O75844 1 +Androgen metabolic process 0.6455667951413133 0.9395183541043798 0.3474646732958497 1.0 0.7012133974339693 4 O95470 1 +Positive regulation of membrane permeability 0.459399996611849 0.9382475427243518 0.3481172109867341 1.0 0.7014366717017879 13 P45880 1 +Negative regulation of binding 0.3500426461096149 0.9360362452359356 0.349254526417381 1.0 0.7020253028549671 35 P40855,Q7Z5K2,O75381,P09601,P49841,P55061,Q14012,Q7L2J0,P16615,Q08209,Q9GZU8,Q6IAN0 12 +Negative regulation of wnt signaling pathway 0.4063552217901615 0.9350908397334298 0.3497414869170741 1.0 0.7020253028549671 20 Q13641,Q9UKV5,P50402,Q8NBM4 4 +Response to endoplasmic reticulum stress 0.3090362137651623 0.9349059543288554 0.3498367682433161 1.0 0.7020253028549671 91 Q8NBM4,O60858,Q13144,P41440,Q9UBU6,Q96CS3,P51572,Q96A33,O60313,Q7Z2K6,Q9UM00,Q8TCJ2,Q4ZIN3,Q9GZP9,Q9UKV5,Q15363,Q9UMX0,P16615,P57088,P55061,P27824,Q9UBV2,Q9H3N1,Q6NTF9 24 +Response to ether 0.6439396107644547 0.9326456545856178 0.3510029528822707 1.0 0.7039302955467929 4 P11802,Q9H4A6 2 +Defense response to symbiont 0.3316296780501733 0.9324674056114312 0.3510950237986785 1.0 0.7039302955467929 58 Q9HCL2,O75844,O43657,O60858 4 +Negative regulation of neuron apoptotic process 0.3970381043564676 0.930632696061012 0.3520435954659104 1.0 0.7050848861140705 23 P50897,P09601,P04062 3 +Glycerol ether metabolic process 0.5429564693745318 0.9286074793943876 0.3530925443091877 1.0 0.7050848861140705 7 Q6PIU2,O15228,Q6IAN0 3 +Protein localization to lysosome 0.4687340559977481 0.9273635918462289 0.3537377872737348 1.0 0.7050848861140705 12 Q9NQC3 1 +Cellular response to uv c 0.6695869837296547 0.9212570099516108 0.3569162601169862 1.0 0.7050848861140705 2 Q9P2X3 1 +Response to uv c 0.6695869837296547 0.9212570099516108 0.3569162601169862 1.0 0.7050848861140705 2 Q9P2X3 1 +Regulation of thymocyte apoptotic process 0.6695869837296549 0.92125700995161 0.3569162601169866 1.0 0.7050848861140705 2 P00813 1 +Insulin metabolic process 0.7289482859175089 0.9210305240368162 0.3570344908977882 1.0 0.7050848861140705 3 Q8TAD4 1 +Smad protein signal transduction 0.5047169075039676 0.9209862178781588 0.357057622601385 1.0 0.7050848861140705 8 Q9UIQ6,P08670 2 +Excretion 0.5789026651187843 0.920444618786994 0.3573404611536781 1.0 0.7050848861140705 6 P09601 1 +Cellular response to arsenic containing substance 0.4960203760730222 0.9199183457090084 0.3576154311268227 1.0 0.7050848861140705 9 P09601,Q96QD8 2 +Amyloid precursor protein biosynthetic process 0.613368979536986 0.9197691831304794 0.3576933906075534 1.0 0.7050848861140705 5 Q9Y287,Q9NQX7 2 +Cellular response to retinoic acid 0.49595152936892 0.919539358605339 0.3578135288069326 1.0 0.7050848861140705 9 Q9P0J0,Q99623 2 +Cellular response to oxygen glucose deprivation 0.6689612015018758 0.9185304208038946 0.3583412401583028 1.0 0.7050848861140705 2 O95831 1 +Response to oxygen glucose deprivation 0.6689612015018758 0.9185304208038946 0.3583412401583028 1.0 0.7050848861140705 2 O95831 1 +Regulation of ion transport 0.3146333973772321 0.918000172422018 0.3586187755908396 1.0 0.705250901131545 84 P14174,Q13586,Q9BVC6,P27105,Q4KMQ2,Q15041,Q7L0J3,P08183,O75844,P17302,P21796,P20020,P23634,Q99623,O75323,Q96PU5,Q8TAD4,Q9UMX0,Q9HD26,Q96BY9,P78417,P55061,P05023,Q00535 24 +Behavior 0.3189930517102717 0.9146842148370168 0.3603574335228414 1.0 0.7073804397209069 78 P50897,Q7Z4L5,Q8NBU5,Q8N2K0,P51790,P04062,O75844,Q9GZP9,Q9UKV5,Q13641,O15118,P50416,O00264,P04035,Q9NWW5,P17900,Q9H5K3 17 +Sulfur compound biosynthetic process 0.3399163426366783 0.9133716416611336 0.3610471149937904 1.0 0.708414638556195 42 O43505,P50897,O95563,Q13126,Q93063,Q99735,P35610,Q8NCH0,Q8TB61,Q11206,Q15118,Q6Y1H2,P25325,Q53GQ0,Q9NZ01 15 +Mitochondrial outer membrane permeabilization involved in programmed cell death 0.466242850917144 0.912358495324066 0.3615800307077519 1.0 0.7084944700492264 12 P45880 1 +Detection of biotic stimulus 0.6109617661400754 0.9091571443845357 0.3632671821347459 1.0 0.7096007675002002 5 Q8WTV0 1 +Antigen processing and presentation of peptide antigen 0.4655212384817078 0.9080128663617152 0.3638714239361036 1.0 0.7097576418669267 12 Q6P179,Q9UIQ6,Q03519,Q9Y6B6,Q9NZ08,P04439 6 +Neuron development 0.2796570409835837 0.904069077685824 0.3659587738214429 1.0 0.7118981617590558 182 Q9NQC3,Q8WWV3,O14949,P08670,P50897,P41440,O75503,Q9NQX7,Q8NBN7,Q9NR77,Q96G23,Q14108,O14966,Q8N0X7,Q969V5,P35613,Q13641,Q96PU5,Q9NZJ7,Q32P28,P42892,P61026,P04062,Q16739,Q9Y6M7,O00264 26 +Regulation of sprouting angiogenesis 0.6367984205432082 0.9025433108175084 0.3667683250184455 1.0 0.7123048628790204 4 P57105 1 +Epithelial cell maturation 0.6366594837922728 0.9019586673799668 0.3670788245441878 1.0 0.7123640637031435 4 P17302,Q86UL3 2 +Skeletal muscle acetylcholine gated channel clustering 0.6089185688094073 0.900158106757268 0.3680361169279273 1.0 0.7134007497527123 5 O15258,P49354 2 +Cellular response to hydroperoxide 0.6645807259073769 0.8994815828359641 0.3683962013733484 1.0 0.7134007497527123 2 P10620 1 +Glycolytic process through fructose 6 phosphate 0.4919009177492615 0.8972499288311591 0.369585568225393 1.0 0.7136127143704365 9 Q9BRR6 1 +Phosphorylation of rna polymerase ii c terminal domain 0.5739139778950932 0.8972290698734282 0.3695966963179393 1.0 0.7136127143704365 6 Q8WUA2,P50750,P32780 3 +Carbohydrate derivative catabolic process 0.3501556946732386 0.8941021152184817 0.3712672576838156 1.0 0.7149904870518108 34 P49902,P15586,Q13126,P04062,P35610,O60502,P08236,P17900,Q8TCJ2,Q9BTY2 10 +Positive regulation of lipid storage 0.6344004099014937 0.8924582909938593 0.3721473391818142 1.0 0.7150363445138523 4 Q8WTV0 1 +Regulation of lipid biosynthetic process 0.3789248336025586 0.8923290012321122 0.372216614004965 1.0 0.7150363445138523 27 P11802,Q12770,Q9UBM7,P05023,Q8NF37,Q8WTV0,Q13510,P16435,Q92604 9 +Ventricular cardiac muscle cell membrane repolarization 0.72150888655019 0.8917649590703332 0.372518927257814 1.0 0.7150363445138523 3 O75844 1 +Negative regulation of blood circulation 0.7213089418596151 0.8909802638858783 0.3729397582957909 1.0 0.7150363445138523 3 P16615 1 +Regulation of protein localization to plasma membrane 0.3824156584181267 0.8907797938520464 0.3730473173257191 1.0 0.7150363445138523 26 P23634,Q9BXS4,O15400,Q9UNK0,O00264,O15258,P98194,Q9HD26 8 +Response to vitamin d 0.6339793913961926 0.8906889482488867 0.3730960654238688 1.0 0.7150363445138523 4 Q8TB36 1 +Antiviral innate immune response 0.6064621694451111 0.8893497027981944 0.3738151673220495 1.0 0.715990459576296 5 Q9NVI7 1 +Cellular response to ether 0.7207436045286985 0.8887621088780694 0.3741309437762319 1.0 0.7161713895651503 3 Q9H4A6 1 +Regulation of protein localization to cilium 0.7206083618892056 0.8882315915039841 0.3744161886525199 1.0 0.7163188504346377 3 Q10713 1 +Positive regulation of protein targeting to membrane 0.4812300456103641 0.8860077569156155 0.3756133472853868 1.0 0.7173117685544479 10 P31751,Q00535,P27105,Q9Y3D6 4 +Regulation of store operated calcium channel activity 0.7186228482003032 0.8804483985318997 0.3786164474656783 1.0 0.719226782506027 3 Q13586,Q9UMX0 2 +Store operated calcium entry 0.7186228482002913 0.880448398531853 0.3786164474657036 1.0 0.719226782506027 3 Q13586,Q96BY9 2 +Regulation of torc2 signaling 0.658948685857314 0.8750907714577825 0.3815245180088249 1.0 0.7219766435388192 2 Q9NWS0 1 +Regulation of neuron projection development 0.3198066867601933 0.8715066037521483 0.3834776017091972 1.0 0.7246327119012916 73 Q9NQC3,Q9NQX7,Q9NR77,Q8WWV3,Q96G23,Q96PU5,Q14108,P08670,Q32P28,O14966 10 +Actin mediated cell contraction 0.4256076884850796 0.8693419955561283 0.3846600992273719 1.0 0.7249621905065669 15 Q9UM22,P16615 2 +Negative regulation of protein maturation 0.7150781918937522 0.8665791302472178 0.3861726524459674 1.0 0.7256756056009711 3 Q9BXS4 1 +Negative regulation of leukocyte migration 0.5664902562280907 0.8627614002348157 0.388268665865128 1.0 0.7277366943177261 6 P09601,P14174,Q5JRA6 3 +Regulation of tetrapyrrole metabolic process 0.7131582903068121 0.8590813048146537 0.3902956608532903 1.0 0.7302681527614217 3 Q9P0S9 1 +Retrograde transport vesicle recycling within golgi 0.7131055965918762 0.8588756633280096 0.3904091175146043 1.0 0.7302681527614217 3 Q8TBA6 1 +Tooth mineralization 0.7126760563380308 0.8571996379832316 0.3913345625254414 1.0 0.730393675054701 3 Q13586,Q6P4Q7 2 +Enamel mineralization 0.7126760563380308 0.8571996379832316 0.3913345625254414 1.0 0.730393675054701 3 Q13586,Q6P4Q7 2 +Amelogenesis 0.7126760563380308 0.8571996379832316 0.3913345625254414 1.0 0.730393675054701 3 Q13586,Q6P4Q7 2 +Bicarbonate transport 0.7126760563380111 0.8571996379831541 0.3913345625254842 1.0 0.730393675054701 3 Q9Y6M7,Q9UHQ9 2 +Negative regulation of steroid metabolic process 0.6259515490379518 0.8570296885399885 0.3914284772208112 1.0 0.730393675054701 4 Q12770 1 +Negative regulation of nitric oxide metabolic process 0.7121993830544889 0.8553403117354988 0.392362776882363 1.0 0.7304186231320616 3 P23634 1 +Walking behavior 0.5985011296285419 0.8544063139132534 0.3928798987428459 1.0 0.730530075453429 5 O15118,O75844 2 +Copper ion transport 0.7114477062167811 0.8524096061988593 0.3939867903249521 1.0 0.7312539452202724 3 Q8N4V1 1 +Epithelial cell apoptotic process 0.474852450598372 0.8499671184243941 0.3953433676629583 1.0 0.7325809352967046 10 P09601 1 +Antigen processing and presentation of peptide antigen via mhc class i 0.4660974831946566 0.8498996082074364 0.3953809034288302 1.0 0.7325809352967046 11 Q6P179,Q9UIQ6,Q03519,Q9Y6B6,Q9NZ08,P04439 6 +Negative regulation of intracellular estrogen receptor signaling pathway 0.5636687421125807 0.8496896198690239 0.3954976709782669 1.0 0.7325875576907107 6 Q99623,Q92600 2 +Mitochondrion localization 0.4103933984939857 0.8468206484565436 0.3970950972237959 1.0 0.7330448222843315 16 Q9BUK6,O60313,Q969V5,O75153,Q8IWA4 5 +Detection of external biotic stimulus 0.7099424431127036 0.8465456172930085 0.3972484371038498 1.0 0.7330448222843315 3 Q8WTV0 1 +Reactive nitrogen species metabolic process 0.4095762003998111 0.8411316011844948 0.4002742133322781 1.0 0.7350291470361643 16 O43169,P16435,P23634,Q08722 4 +Myeloid leukocyte mediated immunity 0.4432702472720189 0.8377759942023995 0.4021565235135518 1.0 0.7369074236069386 13 P09601 1 +Negative regulation of mitochondrial fusion 0.6203010749368755 0.8334342778166622 0.4045998494239524 1.0 0.7378259438835181 4 Q969V5 1 +Vasoconstriction 0.6202189404611285 0.8330919265592359 0.4047928864905965 1.0 0.7378259438835181 4 P42892 1 +Cyclic gmp amp transmembrane import across plasma membrane 0.7064162754303432 0.8328349013736213 0.4049378480646255 1.0 0.7378259438835181 3 P41440,Q8TDW0 2 +Guanine nucleotide transmembrane transport 0.7064162754303432 0.8328349013736213 0.4049378480646255 1.0 0.7378259438835181 3 P41440,Q8TDW0 2 +Guanine nucleotide transport 0.7064162754303432 0.8328349013736213 0.4049378480646255 1.0 0.7378259438835181 3 P41440,Q8TDW0 2 +Positive regulation of blood circulation 0.5934943942928984 0.8325045359919223 0.4051242189088611 1.0 0.7379577666136079 5 P16615 1 +Regulation of defense response to virus by host 0.4880226952413703 0.8317419389429015 0.4055546227255253 1.0 0.738530451435155 8 Q969V5,Q7Z434 2 +Regulation of regulated secretory pathway 0.3946953615847873 0.8308968210200163 0.4060319196849979 1.0 0.738530451435155 19 P09601,Q4J6C6,P11279,P49841,P16615 5 +Regulation of cell killing 0.4797717076817893 0.8306366510138486 0.4061789233103681 1.0 0.738530451435155 9 O15400,P15151,P11279 3 +Positive regulation of epithelial cell migration 0.3752411979201177 0.8305549818484828 0.4062250753178864 1.0 0.738530451435155 26 P09601,Q9NQC3,Q8WTV0 3 +Positive regulation of neurotransmitter uptake 0.6479974968710809 0.8280188320303974 0.407659834887712 1.0 0.7395755445508699 2 P05556 1 +Negative regulation of myeloid leukocyte differentiation 0.6189730745147102 0.8279012206751251 0.4077264435966476 1.0 0.7395755445508699 4 P21359,Q00534,Q13619 3 +Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization 0.6476846057571884 0.8266813019123193 0.4084177220816349 1.0 0.7402493698516446 2 Q709C8 1 +Maintenance of protein location 0.3545765939458433 0.8244653456523154 0.4096751986083109 1.0 0.7420704968914045 31 P24390,Q9H4A6,O15258,P52789,O94901 5 +Entry into host 0.3543507603948835 0.8223725562865021 0.4108648936480294 1.0 0.7440172332652621 31 P35613,O15118,Q14108,Q8WTV0,P11279,Q9BTY2 6 +Positive regulation of receptor mediated endocytosis 0.4696669905219677 0.8207115675845493 0.4118105802606404 1.0 0.7448417887534278 10 P50897,Q8NBU5 2 +Natural killer cell mediated immunity 0.4696404982700753 0.820562232253882 0.4118956677917982 1.0 0.7448417887534278 10 P15151,P11279 2 +Cellular modified amino acid metabolic process 0.3223934730570311 0.8194064482183543 0.412554557185824 1.0 0.7458248866219702 56 P41440,Q8NBM8,Q99735,P78417,Q9UHG3,O60725,Q8TB36,Q9H7Z7,P23786,P16435,Q8N2K0,Q9BVG9,Q9H2D1 13 +Regulation of l glutamate import across plasma membrane 0.7023474178403583 0.817061080937033 0.4138935227350682 1.0 0.7459739942419757 3 O75915,Q15041 2 +L glutamate import across plasma membrane 0.7023474178403583 0.817061080937033 0.4138935227350682 1.0 0.7459739942419757 3 O75915,Q15041 2 +Regulation of amino acid transmembrane transport 0.7023474178403583 0.817061080937033 0.4138935227350682 1.0 0.7459739942419757 3 O75915,Q15041 2 +Protein hydroxylation 0.4176556676844914 0.8161062276739564 0.4144393823787826 1.0 0.7465214814237354 15 Q96HE7,O75718,Q92791,O15460,Q32P28 5 +Regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.4663171944313439 0.8018405909779539 0.4226451751941051 1.0 0.7518614408381785 10 P09601 1 +Regulation of developmental growth 0.3209820521370871 0.8017124450530139 0.4227193152170982 1.0 0.7518614408381785 54 Q8N0X7,Q9NQC3,Q9HCL2,O75844,Q969V5,Q96PU5,O95470 7 +Cerebellar cortex morphogenesis 0.4744860816460536 0.8016906035397511 0.4227319525886139 1.0 0.7518614408381785 9 P04062,Q7Z4L5,O15020 3 +Positive regulation of monocyte chemotaxis 0.6964006259780687 0.7941026445115811 0.4271356782189781 1.0 0.7575248867378589 3 Q4KMQ2,P09429 2 +T cell mediated immune response to tumor cell 0.6955402833244262 0.7907909722669377 0.4290659788863058 1.0 0.75816891181562 3 P04439 1 +Adenylate cyclase inhibiting g protein coupled receptor signaling pathway 0.4802800684367681 0.7905220605523638 0.4292229438956167 1.0 0.75816891181562 8 Q9NZJ7 1 +Positive regulation of protein localization to membrane 0.363161631120744 0.789010348042994 0.4301059584489477 1.0 0.759255449574381 28 P31751,P23634,P27105,O00264,O15258,P98194,Q00535,Q14696 8 +Regulation of steroid metabolic process 0.401973218803132 0.7882544964526124 0.4305478582392212 1.0 0.759255449574381 16 Q12770,Q9UBM7,P05023,Q13510,P16435 5 +Negative regulation of muscle tissue development 0.6089977322648058 0.7865042894905802 0.4315721070635141 1.0 0.759255449574381 4 Q8NFG4,Q8IXJ6 2 +Peptide transport 0.3430241816541753 0.7857368747975572 0.4320216553079543 1.0 0.7595576099352563 33 P62820,Q92543,P50416,Q9BRT2,Q03519,Q16836,P00367,P17302,Q08209,Q8N5M9,P40939,P33527,O95563 13 +Regulation of muscle organ development 0.4709336518238017 0.7822719217428344 0.434054784521046 1.0 0.7603310435266871 9 P41440,Q8IXJ6 2 +Voluntary musculoskeletal movement 0.693100712383864 0.781414413766737 0.4345587963543287 1.0 0.7603310435266871 3 P18887 1 +Regulation of vascular endothelial growth factor receptor signaling pathway 0.6073579149200053 0.7797288271866868 0.4355505070969716 1.0 0.7614486444980012 4 O75340,O14964 2 +Negative regulation of vascular endothelial growth factor receptor signaling pathway 0.6073579149200053 0.7797288271866868 0.4355505070969716 1.0 0.7614486444980012 4 O75340,O14964 2 +Fat cell differentiation 0.357801903646665 0.7761140768225085 0.4376816327960191 1.0 0.7637302581439299 29 Q9BZF1,P31751,Q96HE7,Q86X55,Q9BXB4,P14672,Q8TDW0,Q8N4Q0,Q8NFG4,Q8IXJ6,Q9NZ08,Q9BRK5,Q6IAN0 13 +Cd40 signaling pathway 0.6913928012519567 0.7748625215729081 0.4384209002928778 1.0 0.763989202740372 3 P05556,Q99623 2 +Low density lipoprotein particle clearance 0.4330016057139675 0.7740119353122688 0.4389237332164508 1.0 0.763989202740372 13 P09601,P35610,Q92945,Q6PIU2,Q8WTV0 5 +Polyprenol metabolic process 0.6910818311773596 0.7736707049228172 0.4391255481948384 1.0 0.763989202740372 3 Q9H3H5 1 +Tail anchored membrane protein insertion into er membrane 0.4428967151391533 0.772118629549282 0.4400441693382364 1.0 0.763989202740372 12 Q8N4V1,Q9P0I2,Q9NPA0,Q5J8M3,O43681,Q15006,P46379 7 +Regulation of peptidase activity 0.3114878778977882 0.7717727477660172 0.4402490352389092 1.0 0.763989202740372 74 P49755,Q9BXK5,P51572,P51812,Q96A26,Q15392,Q969V5,Q9P0J0,O75340,Q9NZJ7,O00487,P16435,Q15041 13 +Intracellular lipid transport 0.3876967851433233 0.7712229133373356 0.4405748149386048 1.0 0.763989202740372 17 Q96JX3,O15118,P23786,O14678,Q9H1P3 5 +Gtp metabolic process 0.4325203146412404 0.7710291817835685 0.440689634792635 1.0 0.763989202740372 13 Q8IWA4,O60313 2 +Positive regulation of coagulation 0.6900920099528455 0.7698794771158189 0.4413713889132031 1.0 0.763989202740372 3 Q11206 1 +G protein coupled receptor signaling pathway 0.3296313474940184 0.7673462986195975 0.4428756480199054 1.0 0.7659345202446339 39 P42892,Q99720,P07602,Q8NCG7,Q9NZJ7,P63218 6 +Regulation of t cell proliferation 0.4103336020316138 0.7671898948806589 0.4429686200982177 1.0 0.7659345202446339 15 Q9HCL2 1 +Cellular response to acidic ph 0.6326658322903542 0.7630157725455639 0.4454539894731883 1.0 0.7671773101800955 2 Q9P2X3 1 +Response to acidic ph 0.6326658322903542 0.7630157725455639 0.4454539894731883 1.0 0.7671773101800955 2 Q9P2X3 1 +Negative regulation of protein autophosphorylation 0.6326658322903542 0.7630157725455639 0.4454539894731883 1.0 0.7671773101800955 2 Q9P2X3 1 +Positive regulation of protein glycosylation 0.6326658322903541 0.7630157725455627 0.445453989473189 1.0 0.7671773101800955 2 Q08379 1 +Temperature homeostasis 0.3732690273600153 0.762890872643903 0.4455284800320482 1.0 0.7671773101800955 24 Q9UIQ6,O00767,P49748,P17302,Q8NFG4,P23786,P40939,Q16836,Q6IAN0 9 +Cellular response to unfolded protein 0.3441622035626813 0.7609368479532703 0.4466947882663064 1.0 0.7671773101800955 32 Q96HE7,P57088,P48723,P55061,Q9UKV5,Q9GZP9,Q7Z2K6,Q15363,Q9Y4P3,Q6NTF9 10 +Regulation of leukocyte migration 0.3729916544223346 0.7606485397418515 0.4468670191581128 1.0 0.7671773101800955 24 Q11206,P09601,Q08722 3 +Negative regulation of autophagy of mitochondrion 0.6320400500625696 0.760387272375218 0.4470231288915851 1.0 0.7671773101800955 2 P04637 1 +Negative regulation of mitophagy 0.6320400500625696 0.760387272375218 0.4470231288915851 1.0 0.7671773101800955 2 P04637 1 +Vacuolar localization 0.3867390444501096 0.7593000948900508 0.4476730607787216 1.0 0.7671773101800955 18 P09601 1 +Activation of innate immune response 0.3829452485840021 0.7582349357504279 0.4483103502937455 1.0 0.7671773101800955 20 Q9NUD5,Q13177,Q96ST3,Q96PK6,P43243,O94826,Q8WXF1,P23246,Q7Z434,O60828,P12956,Q16512,P07900,Q13153,Q9NZI8,Q15233,P09429,O43318,P78527 19 +Regulation of t cell activation 0.3399937890846484 0.7566426921808592 0.4492639568528429 1.0 0.7684028352937631 33 O96005,Q9HCL2,P30825 3 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.5751963536744719 0.7530479282033975 0.4514211135929913 1.0 0.7702603340822145 5 O15460,Q96HE7,P13674 3 +Post embryonic development 0.4185219038169421 0.7492197852480337 0.4537247459514191 1.0 0.7727648831046275 14 Q9NX62,O95470 2 +Endoplasmic reticulum mannose trimming 0.6841120631035799 0.7470527253411714 0.4550317349276485 1.0 0.7736797188969443 3 O60858 1 +Hormone transport 0.3426129135280314 0.7463409287300191 0.4554614931488916 1.0 0.7738899405774813 32 P62820,Q92543,P50416,P00367,P17302,Q8N5M9,P40939,Q16836,O95563 9 +Dolichyl diphosphate biosynthetic process 0.6837464193173972 0.745661427146139 0.4558719658087478 1.0 0.7743840847018939 3 Q86YN1 1 +Negative regulation of amyloid precursor protein biosynthetic process 0.6834302080288512 0.7444586456117116 0.4565990508821334 1.0 0.7751290504183135 3 Q9Y287 1 +Regulation of membrane repolarization 0.5406898998225935 0.7439703698956847 0.4568944009325077 1.0 0.7751290504183135 6 O75844 1 +Regulation of natural killer cell mediated immunity 0.5406697035891922 0.7438781368155009 0.4569502032752586 1.0 0.7751290504183135 6 P11279,P15151 2 +Post golgi vesicle mediated transport 0.3262120063692657 0.742750434496544 0.4576327889538718 1.0 0.775543181489777 40 Q9NV70,P61026,P61106,Q96RL7,Q8N2H4,Q13636,Q9HD26,Q4J6C6,Q9H4A6,O14828,P98194,P11279,O15027 13 +Positive regulation of vasculature development 0.3733354896807134 0.7419219572387055 0.4581346215084116 1.0 0.7757094330758428 23 P09601,O75340,Q86UE4,Q9NZ08,P52789,P23458 6 +Regulation of dopamine receptor signaling pathway 0.627346683354184 0.7407401561345216 0.4588510064615816 1.0 0.7757094330758428 2 O14744 1 +Positive regulation of dopamine receptor signaling pathway 0.627346683354184 0.7407401561345216 0.4588510064615816 1.0 0.7757094330758428 2 O14744 1 +Positive regulation of cyclase activity 0.6816901408450736 0.7378469816891493 0.4606074399429023 1.0 0.7757094330758428 3 Q13586,Q16539 2 +Regulation of smoothened signaling pathway 0.4465552071656286 0.7366811120670559 0.4613162956773826 1.0 0.7760954160707098 11 Q7Z4L5,Q96J42 2 +Protein localization to microtubule end 0.6260951188986289 0.7355212671567575 0.462022092717901 1.0 0.7770808170660748 2 Q15555 1 +Golgi to endosome transport 0.5386906617381843 0.7348469048973245 0.4624327373760837 1.0 0.7773191341474092 6 Q96RL7,Q8N2H4,P61106 3 +Plasma lipoprotein particle clearance 0.4162366166693815 0.7345643886417829 0.462604832701839 1.0 0.7773191341474092 14 P09601,P35610,Q92945,Q6PIU2,Q8WTV0 5 +Cellular response to chemical stress 0.3056117472867594 0.7338943155963634 0.4630131518103615 1.0 0.7774111990740499 78 P39210,Q8N0U8,Q07820,Q99720,P09601,P04062,Q9BPX6,Q7Z2K6,O95202,Q8TED1,Q8IXJ6,Q6NUK1,Q9UMX0,P16615 14 +Protein localization to organelle 0.2682818852897519 0.7308542336058578 0.4648681930276679 1.0 0.7782349163567917 335 Q9NQC3,Q99595,P24390,Q8N4H5,Q7Z3B4,P46379,Q8N4V1,P13473,Q7Z434,Q9NS69,Q3ZCQ8,P56589,Q8N8Q8,Q9Y276,Q9H4A6,Q15629,Q9Y5M8,Q13561,Q15070,Q9UH99,P49841,Q9Y5J6,Q7Z5K2,O14773,O14925,O43731,Q10713,Q8NFG4,Q8NC56,Q5JRA6,Q00535,Q9Y6C9,Q9BZF1,Q15005,Q9Y679,Q9NPA0,P55786,Q7L2J0,Q15006,Q96JB2,P40855,Q9Y371,Q96A33,Q8N2H4,Q9P0J0,P62072,Q14108,Q9H300,Q8TEX9,O15027,Q7Z4L5,P67809,Q9H1Z9,O00170,O95831,O15258,Q7Z4Q2,P52789,O94901,O14657,O14964,Q9Y3D6,Q8WWC4,Q96DA6,Q96D46,Q15388,Q08209,Q92973,Q9BRG1,Q9Y5J9,Q8NBM4,Q9Y5L0,O43292,P51572,P11279,O14966,P49755,O43681,P61026,O75381,O96008,O43615,P49257,Q8NFH5,Q9Y512,Q8TB36,Q14789,Q99442,Q8IZ07,P61619,Q99623,A0AVF1,Q9UGP8,Q53H12 94 +Positive regulation of wound healing 0.502158476455727 0.7265499072566147 0.4675017241459831 1.0 0.7805078011640406 7 Q11206 1 +Erythrocyte maturation 0.6239048811013848 0.726409433721099 0.4675878096816603 1.0 0.7805078011640406 2 P18074 1 +Peripheral nervous system axon regeneration 0.678394008356912 0.7253562586803199 0.4682335002554989 1.0 0.7806304002198837 3 Q96G23 1 +Positive regulation of bone mineralization 0.6779198437396838 0.7235630812149096 0.4693340137053958 1.0 0.7812576483285293 3 Q4KMQ2 1 +Protein deglycosylation 0.4668969587460656 0.7196495389039318 0.4717408025607854 1.0 0.7843462054264259 8 Q9UKV5,O60502,O60858 3 +Amino sugar metabolic process 0.4587465464751958 0.7159230834368167 0.47403884415065 1.0 0.7858553789300735 9 Q9H3H5 1 +Cellular response to exogenous dsrna 0.4586475046275545 0.7153858521114125 0.4743706522401743 1.0 0.7862040617921658 9 P41440,Q969V5 2 +Regulation of the force of heart contraction 0.5340191281904692 0.7135836886546232 0.4754846467366547 1.0 0.7870426173093681 6 P23634,P05023,P16615 3 +Sodium ion export across plasma membrane 0.6748671116452709 0.7120410287959736 0.4764393697458577 1.0 0.7880182982354182 3 P05023 1 +Positive regulation of lipid biosynthetic process 0.4418612747288632 0.7096431988707357 0.4779254239229116 1.0 0.7892405470840219 11 P16435,Q8WTV0,Q92604 3 +Cdp choline pathway 0.6741843720958823 0.7094695805504452 0.4780331221195726 1.0 0.7892405470840219 3 Q9Y6K0 1 +Positive regulation of biomineralization 0.589465794671694 0.7064253778722168 0.479923643509534 1.0 0.7912180397961911 4 Q4KMQ2 1 +Pallium development 0.3226781814667873 0.7058676176904064 0.4802704671087183 1.0 0.7912180397961911 40 Q96QD8,Q9NQC3,P23634,P07196,O14949,P18887,Q96N66,O94901,P49841,Q13144 10 +Regulation of epithelial cell migration 0.3235962041447769 0.7049416091979027 0.4808465745658665 1.0 0.7912180397961911 39 P09601,P57105,Q9NQC3,Q8WTV0 4 +Autonomic nervous system development 0.6185857321651973 0.7043967092989211 0.4811857547339011 1.0 0.7912180397961911 2 P21359 1 +Sympathetic nervous system development 0.6185857321651973 0.7043967092989211 0.4811857547339011 1.0 0.7912180397961911 2 P21359 1 +Negative regulation of osteoclast differentiation 0.6185857321651973 0.7043967092989211 0.4811857547339011 1.0 0.7912180397961911 2 P21359 1 +Negative regulation of oligodendrocyte differentiation 0.6185857321651973 0.7043967092989211 0.4811857547339011 1.0 0.7912180397961911 2 P21359 1 +Reactive oxygen species biosynthetic process 0.4403249089460535 0.700810375858087 0.4834213619179746 1.0 0.7927372985825683 11 Q15067,P51790,P00403,Q9BSK2 4 +Metal ion export 0.4559165665473805 0.7005866268534349 0.4835610265914447 1.0 0.7927372985825683 9 Q4KMQ2,P20020,O95202,P05023 4 +Negative regulation of type i interferon mediated signaling pathway 0.5308559950534307 0.6992325490378192 0.4844067123234892 1.0 0.7927372985825683 6 Q969V5,Q14166 2 +Regulation of wound healing 0.4107141105590794 0.699222229912246 0.4844131601829 1.0 0.7927372985825683 14 Q11206 1 +Ribonucleoside metabolic process 0.4554953341068799 0.6983064237724349 0.4849855827897529 1.0 0.7927372985825683 9 P49902,Q13126,O60725 3 +Purine ribonucleoside metabolic process 0.4554953341068799 0.6983064237724349 0.4849855827897529 1.0 0.7927372985825683 9 P49902,Q13126,O60725 3 +Liver regeneration 0.4474842218337376 0.696306019162191 0.4862372044562042 1.0 0.7934212053048856 10 P09601,P50416 2 +Xenobiotic metabolic process 0.4203621688993951 0.6959141468762374 0.4864825972105098 1.0 0.7934212053048856 13 O43169,P07099,Q6PIU2,P16435 4 +Positive regulation of t cell mediated cytotoxicity 0.530096340201025 0.6957918328767263 0.4865592046704323 1.0 0.7934212053048856 6 O15400,P15151 2 +Regulation of t cell mediated cytotoxicity 0.530096340201025 0.6957918328767263 0.4865592046704323 1.0 0.7934212053048856 6 O15400,P15151 2 +Negative regulation of lipid localization 0.5866827083925541 0.695136407767442 0.4869698202772738 1.0 0.7934714694950948 4 Q9BZF1,P31751 2 +Glycoside metabolic process 0.4548279746747519 0.6946953012368816 0.4872462733348639 1.0 0.7934919283192672 9 P04062,Q9BTY2 2 +Generation of precursor metabolites and energy 0.2710462204008076 0.694141109463722 0.487593719977399 1.0 0.7934919283192672 193 O95298,Q7KZN9,O96000,Q9BRT2,Q9BRR6,O14949,Q9Y6M9,O95139,Q15067,P10253,O43676,Q9Y6N1,P03886,Q12797,Q13423,P46020,P13807,P00403,P35610,P12235,Q9P0J0,P24539,Q9H3K2,P20674,Q9H936,Q9Y375,O75208,O75964,Q9BSK2,P56385,Q99623,P13073,P22830,O75323,P03915,Q15070,O15460,P52789,P49841,P31751,P00846,P21912,P04062,P56134,O75306,O43819,O95169,P36542,Q8NFG4,P16435,Q9UDW1,P51970 52 +Sphingomyelin metabolic process 0.5296879211193719 0.6939429307169462 0.4877179992048894 1.0 0.7934919283192672 6 O15269 1 +Regulation of erbb signaling pathway 0.4379773251708946 0.6873311427734197 0.4918740780498094 1.0 0.7956237287611508 11 Q9NQC3 1 +Neurotransmitter transport 0.3476931999979889 0.6864943781134916 0.4924014082518873 1.0 0.7956237287611508 29 P41440,P50897,Q96QD8,Q7L0J3,P16615 5 +Regulation of vasoconstriction 0.6680465710533569 0.6864447683897485 0.4924326818824216 1.0 0.7956237287611508 3 P42892 1 +Protein localization to endoplasmic reticulum exit site 0.5840894013436285 0.684647447982898 0.4935664182924963 1.0 0.7962812080906766 4 P51572,Q5JRA6 2 +Regulation of water loss via skin 0.5840510650132221 0.6844926152964029 0.4936641509410444 1.0 0.7962812080906766 4 P04062 1 +Regulation of spontaneous synaptic transmission 0.6132665832290427 0.6825558755435827 0.4948875240495654 1.0 0.7968674451460613 2 P05556 1 +Spontaneous synaptic transmission 0.6132665832290427 0.6825558755435827 0.4948875240495654 1.0 0.7968674451460613 2 P05556 1 +Regulation of receptor internalization 0.4449927905235846 0.6824348607188113 0.4949640187711939 1.0 0.7968674451460613 10 P41440,Q8NBU5 2 +Protein demannosylation 0.5826805844384497 0.6789618675176193 0.4971620236207674 1.0 0.79928218095461 4 O60858 1 +Negative regulation of calcium ion transport 0.4442955131177501 0.6785572636294727 0.4974184290511827 1.0 0.79928218095461 10 P55061,P21796,Q9UMX0 3 +Response to hydroperoxide 0.6647887323943642 0.6742934748589742 0.5001247516645422 1.0 0.8019839922628634 3 P10620,P18887 2 +Complement activation 0.664395599290307 0.6728305256244494 0.5010551152067817 1.0 0.802175634431778 3 Q99623 1 +Regulation of humoral immune response 0.664395599290307 0.6728305256244494 0.5010551152067817 1.0 0.802175634431778 3 Q99623 1 +Regulation of complement activation 0.664395599290307 0.6728305256244494 0.5010551152067817 1.0 0.802175634431778 3 Q99623 1 +Regulation of fatty acid transport 0.5563383075153077 0.6723693264224002 0.5013486051490676 1.0 0.802175634431778 5 P31751,P14174,Q9Y3D6 3 +Positive regulation of cholesterol metabolic process 0.6631820097937247 0.6683191173124579 0.5039299127560777 1.0 0.8046722225218221 3 P16435 1 +Positive regulation of steroid metabolic process 0.6631820097937247 0.6683191173124579 0.5039299127560777 1.0 0.8046722225218221 3 P16435 1 +Neuron death 0.3035771533949689 0.6676277801327545 0.5043712203110906 1.0 0.8046722225218221 74 P50897,Q4ZIN3,Q07820,Q99720,P09601,P04062,Q96A26,Q15392,Q01105 9 +Response to dexamethasone 0.489118028885423 0.6630055365047289 0.5073270081996011 1.0 0.8072879015759183 7 P04062 1 +Export across plasma membrane 0.4412870692394466 0.6618509871024122 0.5080667257569931 1.0 0.8079134764371645 10 P17302,Q4KMQ2,P05023,P08183 4 +Torc2 signaling 0.6591549295774617 0.6534002853690883 0.5134982548932361 1.0 0.8135521923302383 3 Q96A49,Q9NWS0 2 +Cardiac muscle cell membrane repolarization 0.4868197917218781 0.651881162382162 0.5144778380196582 1.0 0.8149046910580586 7 O75844,P05023 2 +Water homeostasis 0.4391142172368022 0.649810056017758 0.5158149224976805 1.0 0.8166228420755841 10 P04062,Q96PU5 2 +Receptor signaling pathway via stat 0.3925726904636011 0.6492321962638604 0.5161883041120916 1.0 0.8168143531084247 15 Q00535,Q9H490,Q9NX40,P23458 4 +Regulation of dna damage response signal transduction by p53 class mediator 0.4388365786556343 0.6482730992071545 0.5168083297955461 1.0 0.8169964607808439 10 Q9UNS2,O75844 2 +Toxin transport 0.4219487964932624 0.6474902759035153 0.5173146859562936 1.0 0.8172360445145613 12 Q93050 1 +Protein localization to cilium 0.4124694402264098 0.6474531583017722 0.51733870123241 1.0 0.8172360445145613 13 Q7Z4L5,Q10713,O14966,A0AVF1 4 +Steroid catabolic process 0.5739711567096738 0.6440196283967649 0.519562705899576 1.0 0.8197001619872841 4 Q8WTV0 1 +Response to retinoic acid 0.4212823407508206 0.6435547215369114 0.5198642193910148 1.0 0.8197001619872841 12 Q9P0J0,Q99623,Q8TB36 3 +Mitochondrial dna metabolic process 0.4849970733884415 0.6430760534093871 0.5201747519670836 1.0 0.8197001619872841 7 P51530,P39210 2 +Negative regulation of neuron death 0.3166185290227159 0.6427398109751611 0.5203929440458637 1.0 0.8197001619872841 40 P50897,P09601,Q4ZIN3,P04062 4 +Regulation of phosphatidylcholine metabolic process 0.5481553745388914 0.6378345644580496 0.5235813770171152 1.0 0.8231357894290471 5 Q8NF37 1 +Response to toxic substance 0.3073796101163862 0.6366711389825069 0.5243390765739662 1.0 0.8231357894290471 47 Q7Z5K2,Q99735,P08183,P04818,P78417,P07196,Q9BRX8,O14880,P27544,P25325,P36551,Q8TC12,Q8TED1,P07099,Q15165 15 +Positive regulation of mononuclear cell migration 0.4510079858614481 0.6363501214717358 0.5245482432497521 1.0 0.8231357894290471 8 Q08722 1 +Vesicle fusion with golgi apparatus 0.5475127107696869 0.6351359988064457 0.5253397203923096 1.0 0.8231357894290471 5 Q9BSR8,Q13190 2 +Negative regulation of defense response to virus 0.5166096260703167 0.6351189294248357 0.5253508521436823 1.0 0.8231357894290471 6 O43657 1 +Regulation of cell death 0.2638933464809374 0.6346114735396451 0.5256818432514707 1.0 0.8231357894290471 338 P14174,Q9NQC3,Q07820,Q99720,Q9BVC6,P07196,Q9HCL2,Q96A26,Q15392,O60858,P45880,Q4KMQ2,Q15041,Q13144,P50897,Q9NQX7,P00403,P09601,P51572,O60313,Q9Y241,P12235,Q9NS69,Q9P0J0,O15118,O15269,P21796,Q9H4A6,Q9H3K2,Q9H300,O14966,Q8N2F6,Q14155,Q8IWB1,Q9BXK5,Q4ZIN3,Q99623,Q86XL3,Q86UE4,Q9NZJ7,Q8IXJ6,Q9NVI7,Q6NUK1,Q9UMX0,Q7Z3C6,P31751,P04062,P51812,P55061,P15291,P05141,Q12981,Q13510,P16435,Q01105,Q9Y6C9,Q9NR28 57 +Cobalamin metabolic process 0.5715235998125208 0.6342672259362022 0.5259064414847203 1.0 0.8231357894290471 4 O14678 1 +Response to sterol depletion 0.4830244410128756 0.6335648699069109 0.5263648332938493 1.0 0.8232155711398434 7 Q15363,Q9UKV5 2 +Cellular response to sterol depletion 0.4830244410128756 0.6335648699069109 0.5263648332938493 1.0 0.8232155711398434 7 Q15363,Q9UKV5 2 +Acylglycerol homeostasis 0.6534343826303977 0.6323486241730955 0.5271590970672895 1.0 0.8239009119100452 3 Q9BWH2 1 +Protein lipid complex subunit organization 0.515040291466027 0.6281138869802274 0.5299293364864219 1.0 0.8256385810640642 6 Q8WTV0 1 +Bone remodeling 0.4345317435816289 0.6244906694680767 0.532305396096632 1.0 0.8275832325243719 10 Q92791,O14773 2 +Positive regulation of dna demethylation 0.5982478097622014 0.6218999044300526 0.5340076879753135 1.0 0.8293127561363834 2 Q93008 1 +Regulation of ossification 0.4412409326811351 0.621594897129107 0.5342082772571626 1.0 0.8293127561363834 9 Q4KMQ2,P17302,O75844 3 +Phagosome maturation 0.5668470066653643 0.615720178827079 0.5380792169620416 1.0 0.8320085215740667 4 Q13636,P61106 2 +Regulation of ion transmembrane transport 0.30424433988815 0.614625665683163 0.5388019606735992 1.0 0.8322497110929675 63 Q13586,Q9BVC6,P27105,Q4KMQ2,Q15041,Q13546,P08183,O75844,P17302,P21796,O00483,P23634,Q99623,O75323,Q96PU5,Q8TAD4,Q9UMX0,Q9HD26,P78417,Q00535 20 +Negative regulation of transcription from rna polymerase ii promoter in response to stress 0.5418453764368814 0.6114304663138939 0.5409146383064249 1.0 0.8340921042845878 5 P55061 1 +Positive regulation of epithelial cell proliferation 0.3592440236546313 0.6111223151956242 0.5411186076158048 1.0 0.8340921042845878 22 Q9NQC3 1 +Regulation of er associated ubiquitin dependent protein catabolic process 0.5653440681935409 0.6097846842340904 0.5420044484172073 1.0 0.8345996669230127 4 P51572 1 +Astrocyte development 0.5413682631385927 0.6094425180720204 0.542231162742493 1.0 0.8345996669230127 5 P08670 1 +External encapsulating structure organization 0.3387384959328451 0.6074859961450537 0.5435284333707464 1.0 0.8348446562505158 29 P41440,P39210,Q96JX3,P15291,Q53GQ0,Q92791,O75718 7 +Sensory perception of pain 0.5640296749750132 0.6046040714968 0.5454421007377446 1.0 0.8360486703330051 4 Q00535,Q9H5K3 2 +Protein k11 linked ubiquitination 0.4769664681918113 0.6044803328411453 0.5455243409790298 1.0 0.8360486703330051 7 Q9UJX5,Q9UJX4,Q9UJX3,Q9UJX2,P30260,Q9H1A4 6 +Response to amyloid beta 0.5092196867465952 0.6022430021199717 0.5470123952032959 1.0 0.8371398017866473 6 P49841,P17302,Q00535 3 +Cellular response to amyloid beta 0.5092196867465952 0.6022430021199717 0.5470123952032959 1.0 0.8371398017866473 6 P49841,P17302,Q00535 3 +Neuroblast proliferation 0.4139575046963061 0.6004527934171816 0.5482045126844803 1.0 0.8378640768248974 12 Q8NCG7 1 +Maternal placenta development 0.5629448302707203 0.6003355319373683 0.5482826430186494 1.0 0.8378640768248974 4 P35613 1 +Magnesium ion homeostasis 0.6445147892438476 0.5998740125583304 0.548590202903976 1.0 0.8378640768248974 3 Q8NE01 1 +Eating behavior 0.6444109512773608 0.5994985801354817 0.5488404566296285 1.0 0.8379559885130823 3 Q7Z4L5 1 +Import into cell 0.3444849143500018 0.5989180372739578 0.5492275426618032 1.0 0.8382820961671424 27 P41440,P31751,O75915,P23634,O14975,P05023,Q8TDW0,Q15043,Q9BXP2,Q15041,P30825 11 +Positive regulation of tor signaling 0.4364304203162829 0.5959333076343346 0.5512197811228257 1.0 0.8394104525710417 9 Q9P2J5,Q8NFG4,Q9H4A6,P55735,Q9NWS0 5 +Alcohol catabolic process 0.428577759418622 0.5917588608818929 0.55401207497303 1.0 0.8407517124083798 10 Q10713,Q9NX62 2 +Positive regulation of natural killer cell mediated cytotoxicity 0.5607457648197247 0.5917035140879787 0.5540491429885259 1.0 0.8407517124083798 4 P11279 1 +Positive regulation of natural killer cell mediated immunity 0.5607457648197247 0.5917035140879787 0.5540491429885259 1.0 0.8407517124083798 4 P11279 1 +Regulation of potassium ion transport 0.4208425236031973 0.5897102012482757 0.555384954848569 1.0 0.8422255993698035 11 Q96PU5 1 +Feeding behavior 0.4737820534241009 0.5892718001705358 0.5556789587437454 1.0 0.84237230256867 7 Q7Z4L5,Q9GZP9 2 +Positive regulation of interleukin 12 production 0.6412579559692346 0.5881285349575124 0.5564460212844282 1.0 0.8430053019084315 3 P09429 1 +Neutrophil migration 0.3831319808921819 0.587137261931174 0.5571115237955808 1.0 0.8432239901789053 15 Q8N5M9 1 +Regulation of programmed necrotic cell death 0.4342951951585306 0.5845851101282818 0.558826722012074 1.0 0.8445648236476424 9 Q13510 1 +Asymmetric cell division 0.505150553205348 0.584265999748453 0.5590413634898794 1.0 0.8445648236476424 6 P61026,P61158,P61160,Q96N67 4 +Calcium mediated signaling 0.3529779877210807 0.5811665659442201 0.5611281987752541 1.0 0.8464528820797194 23 P23634,Q9Y3D6,P78417,P51572,O75844,P42345,Q08209,P49841,P16615 9 +Golgi to plasma membrane transport 0.3453170538998823 0.5807705127908848 0.5613951310167433 1.0 0.8464528820797194 26 Q9NV70,P61026,Q8N2H4,Q9HD26,Q4J6C6,Q9H4A6,Q13636,P98194,O15027 9 +Regulation of gliogenesis 0.4013503449584233 0.579721378418294 0.5621025241957089 1.0 0.8464705908176781 13 Q96G23 1 +Ether biosynthetic process 0.5338042308395663 0.5780958458539911 0.5631994115354555 1.0 0.8470603925914326 5 O15228,Q6IAN0 2 +Immune response regulating signaling pathway 0.3017327712117813 0.5769253199088746 0.5639899053446893 1.0 0.847884475584397 54 P41440,Q9UMX0,Q9NPR9,Q9NQC3,O14966,O43657,P51812,Q99623,Q08722,P04439,P46379,Q13144 12 +Nucleoside bisphosphate metabolic process 0.3058351770580152 0.5750956921850983 0.5652265812012969 1.0 0.8493490674564182 44 P50897,Q9HCL2,Q8TB61,Q86UL3,Q6Y1H2,Q53GQ0,P04035,Q9NZ01,Q8WVC6 9 +Protein heterotetramerization 0.4706988404888974 0.5746025871215045 0.5655601019691925 1.0 0.8496529665609596 7 Q9NSD9,Q16630,Q8N684,P31350,Q9Y285,O43809 6 +Gdp metabolic process 0.5560425798371983 0.5733375395000978 0.5664161725540493 1.0 0.850443627300001 4 Q14168,O14936,Q00013 3 +Cellular response to vitamin d 0.6368876041235884 0.57246613914157 0.567006219375696 1.0 0.850443627300001 3 Q8TB36 1 +Regulation of stem cell differentiation 0.3597254970634481 0.5705088229198444 0.568332639701969 1.0 0.8512331009701757 17 Q9Y6C9 1 +Neuron maturation 0.5012726541045627 0.5672227662153726 0.5705628423898419 1.0 0.8522026811744995 6 Q9NZJ7 1 +Regulation of nervous system process 0.4375851317191893 0.566943260477953 0.5707527314282075 1.0 0.8522026811744995 8 P04062,P53634,Q9UQB8 3 +Ensheathment of neurons 0.3435685111245908 0.566322487522666 0.5711745762953875 1.0 0.8522026811744995 26 P31751,Q92542,Q9NR77,P49770,P42345,Q16880,O15228,Q8IXJ6,P53634,O75746,Q9Y4W6,Q13144 12 +Receptor mediated endocytosis 0.3022307446904507 0.5636995766529912 0.5729586055619205 1.0 0.8539209889847441 46 P41440,P50897,Q8IZ07,Q8NBU5,Q5VW38,Q13432,Q14108 7 +Cellular response to ph 0.6338236734916797 0.5615553630101782 0.5744190000062805 1.0 0.8539302895240081 3 P17302 1 +Regulation of plasma lipoprotein particle levels 0.3584275986609924 0.5613053120129883 0.5745894209505891 1.0 0.8539302895240081 17 P09601,P35610,Q92945,Q6PIU2,Q8WTV0 5 +Nerve development 0.4364424199945594 0.5610837094817133 0.5747404729861834 1.0 0.8539302895240081 8 Q9H061 1 +Calcium ion regulated exocytosis 0.4228624258955863 0.560535661559525 0.5751141222721712 1.0 0.8539340085072223 10 Q9BRK5,P16615 2 +Negative regulation of protein import into nucleus 0.6328638497652646 0.5581494940625085 0.5767423057226431 1.0 0.854229197647319 3 P61960,P21359 2 +Response to l glutamate 0.5288842637685436 0.5578871003041352 0.5769214806731198 1.0 0.854229197647319 5 P55061,Q9UQB8 2 +Glycolytic fermentation 0.632237871674491 0.5559314046856585 0.5782577485008593 1.0 0.8554249481822997 3 P04637,O75746 2 +Fermentation 0.632237871674491 0.5559314046856585 0.5782577485008593 1.0 0.8554249481822997 3 P04637,O75746 2 +Glycoprotein catabolic process 0.6321197320486489 0.555513069389167 0.5785437732365879 1.0 0.8556524909477141 3 Q8TCJ2 1 +Regulation of response to endoplasmic reticulum stress 0.3494129751606094 0.5532756295096777 0.580074686186639 1.0 0.8573289264672136 23 Q9UMX0,P57088,Q4ZIN3,P51572,P55061,O60313,P46379 7 +Mitotic dna replication 0.4209414454343276 0.5500884605037611 0.5822587010803881 1.0 0.8597714609610477 10 O75844 1 +Heterotypic cell cell adhesion 0.4276188744229952 0.5492841094854305 0.5828104907202578 1.0 0.8600836971407825 9 Q08722 1 +Glycerophospholipid catabolic process 0.4340437888388652 0.5488117870953361 0.5831346203729533 1.0 0.8600836971407825 8 Q8N2K0,Q8WTV0 2 +Negative regulation of apoptotic signaling pathway 0.2971431646808334 0.5453231877981122 0.5855312589968689 1.0 0.8615571452671833 68 Q8N2F6,Q8IWB1,P09601,P55061,Q9P0J0,P45880,Q9H3K2,Q9H300 8 +Head morphogenesis 0.4951148921349228 0.5403493224082729 0.5889561498469871 1.0 0.8636430735579985 6 Q12797,Q15042,O95470 3 +Polyol biosynthetic process 0.4111923228842769 0.5354676300741261 0.592326535337953 1.0 0.86633612128977 11 P04062,Q13510 2 +Cardiac conduction 0.353047681540845 0.5349108319906424 0.5927115177108768 1.0 0.8667033309138714 20 O75844,P05023,P17302,Q6PI78,P20020,P16615 6 +Neuron projection guidance 0.3504597931151048 0.528454176711781 0.5971841436013299 1.0 0.8700211139331445 21 P42892,O00264 2 +Protein localization to cell periphery 0.2846916031267997 0.527937328626127 0.5975428349464909 1.0 0.8700211139331445 87 Q9BXS4,Q15904,Q9UNK0,Q6IQ22,P41440,Q8N2H4,Q4J6C6,Q9H4A6,P98194,O14966,P23634,P35613,Q13641,Q15363,O15258,O15400,O00264,Q9HD26,P61026,P31751,Q13636 21 +Response to estrogen 0.40977622287376 0.5275618975074122 0.5978034446323692 1.0 0.8700211139331445 11 P09601 1 +Synaptic transmission glutamatergic 0.4593381114369334 0.521070776964061 0.6023174674640495 1.0 0.8722753746760635 7 Q8NBU5,Q15042,Q00535,P51790 4 +Camera type eye morphogenesis 0.4219008335769642 0.519289351000311 0.6035589782928077 1.0 0.8730991679063895 9 Q16706,Q15555,P54802,Q8NBN7 4 +Negative regulation of intracellular signal transduction 0.2739134208834172 0.5185544491981029 0.6040714807725691 1.0 0.8733016442482147 98 Q8N2F6,O43657,Q07820,P04062,P55061,Q10713,Q969V5,Q9P0J0,P45880,P57105,P04035,Q9H300 12 +Clathrin dependent endocytosis 0.3991357190371905 0.5142571657270406 0.6070722050227468 1.0 0.8747740723856267 12 Q5VW38,Q13432 2 +Respiratory gaseous exchange by respiratory system 0.3990824521875492 0.5139502705742321 0.6072867594605409 1.0 0.8747740723856267 12 Q7KZN9 1 +Reactive oxygen species metabolic process 0.3010215963763215 0.511318367955669 0.6091281453256747 1.0 0.875283604917355 43 P39210,P00403,Q9BSK2,P52789,Q15067,Q9P0J0,Q8IXJ6,Q13423,Q9H300 9 +Multicellular organismal signaling 0.3339912020495592 0.5107495502005904 0.609526439505168 1.0 0.8755533127961419 27 P04062,O75844,P05023,P17302,Q6PI78,P20020,P16615 7 +Regulation of reactive oxygen species biosynthetic process 0.4196602892928942 0.5076017829084531 0.6117326400316925 1.0 0.8757682403585093 9 P51790,P00403,Q9BSK2 3 +Postsynaptic membrane organization 0.4258143105018888 0.5070125274429682 0.612146028676418 1.0 0.8757682403585093 8 O15258,P49354 2 +Lipid oxidation 0.3024904896979311 0.5057235252421178 0.6130507509505332 1.0 0.8762509850158681 41 P28288,P31751,O43808,Q16134,O14975,P35610,O14678,O15254,P50416,Q15067,A1L0T0,Q709F0,P16435,P23786,P40939,Q16836 16 +Negative regulation of ion transport 0.3496107987520881 0.4995367504036917 0.6174013034608601 1.0 0.8784837801849148 19 P78417,P55061,Q96PU5,P21796,Q9UMX0 5 +Positive regulation of catabolic process 0.2685800628180699 0.4994193089319396 0.617484019174573 1.0 0.8784837801849148 147 Q9BXS4,Q9HBH5,O60858,Q8NF37,Q8NCG7,Q13190,P46379,P09601,Q9Y371,Q12834,P51572,O15269,P12235,Q9P0J0,Q96B26,Q6ZXV5,P21796,O60506,Q4ZIN3,P67809,O75396,Q96PU5,Q86UE4,Q9NZN8,Q8IXJ6,Q969T7,P49841,Q9UMX0,P31751,P04062,P05141,P27544,P43686,Q92945,Q8NFG4,P50416,P53634 37 +Negative regulation of filopodium assembly 0.5663329161451703 0.4988706028354993 0.6178705450249895 1.0 0.8784837801849148 2 Q05655 1 +Positive regulation of smoothened signaling pathway 0.5362013193592182 0.4974293726524538 0.6188862967151203 1.0 0.8791554241308732 4 Q96J42 1 +Sprouting angiogenesis 0.3686676290853222 0.4932026528539874 0.6218694036119408 1.0 0.8804698710719494 15 P09601 1 +Receptor clustering 0.3779832772395376 0.4930343791996537 0.6219882958190595 1.0 0.8804698710719494 14 O15258,P57105,P49354,Q00535 4 +Deoxyribonucleoside triphosphate biosynthetic process 0.6130185938614123 0.4891123422897216 0.6247621639323759 1.0 0.8818889258386776 3 P55263 1 +Negative regulation of cysteine type endopeptidase activity 0.3477690379170919 0.4862671767840723 0.6267777479321786 1.0 0.8835777792674928 17 P16435,Q15392,Q15041 3 +Positive regulation of small molecule metabolic process 0.3667334055786086 0.4807770176367414 0.6306749860194696 1.0 0.8865613617545628 15 P31751,Q12770,P00403,P16435,Q92604 5 +N acetylglucosamine metabolic process 0.5315859214491315 0.4801729205835471 0.6311044403511819 1.0 0.8869724078073504 4 O60502,Q9Y223 2 +Neuropeptide signaling pathway 0.5610137672090009 0.4792667895474557 0.631748845072766 1.0 0.8871075125430574 2 Q9Y3E5 1 +Nerve growth factor signaling pathway 0.561013767209 0.4792667895474535 0.6317488450727675 1.0 0.8871075125430574 2 Q9ULH0 1 +B cell homeostasis 0.6083992239354741 0.4734474300660781 0.6358939981124134 1.0 0.8907503196631639 3 P14174 1 +Urogenital system development 0.2938220865230228 0.4714073549413795 0.6373498647129447 1.0 0.8912982550609719 46 P07602,O75844,O95470,Q9NZJ7 4 +Regulation of cholesterol metabolic process 0.4125120964950526 0.4705821172611476 0.6379391804208314 1.0 0.8913519809334242 9 P16435,Q12770,Q9UBM7 3 +Regulation of lipid storage 0.4184934520572568 0.4702651355044719 0.6381656031357634 1.0 0.8914758867892641 8 Q9BZF1,P50416,Q8WTV0 3 +Interferon gamma production 0.4472899145062227 0.4653149340954197 0.6417059416776822 1.0 0.8935285831622115 7 P04439,Q08722 2 +Negative regulation of map kinase activity 0.4174530644279081 0.4650792056011224 0.6418747367152615 1.0 0.8935713693312912 8 P04062 1 +Negative regulation of immune system process 0.2955648165603702 0.4648150576616032 0.6420639036826927 1.0 0.8936424913192231 44 P09601,P55061,Q9HCL2,Q969V5 4 +Central nervous system neuron differentiation 0.3639472731969628 0.4629433566044211 0.6434049689141648 1.0 0.8951240238203944 15 O14949 1 +Amine catabolic process 0.5041925652373617 0.4589405640956059 0.6462768482058379 1.0 0.8969984476920829 5 Q8WWI5,P21964 2 +Negative regulation of signaling 0.2606701974827079 0.4571854576117958 0.6475377500504043 1.0 0.8979782126261445 200 P50402,O43657,Q07820,Q8NBM4,Q92600,P45880,Q08722,P40939,P09601,Q9P0J0,O75340,Q9H3K2,Q9H300,Q16836,Q8N2F6,Q8IWB1,Q969V5,Q13641,P57105,Q9NPR9,P04062,P55061,Q10713,P04035,Q8N5M9 25 +Protein targeting to peroxisome 0.4755313942820489 0.4566382142824655 0.6479311071979077 1.0 0.8982560666317541 6 P40855,O75381 2 +Regulation of tube size 0.4035032805306378 0.4565205531858997 0.6480156945463009 1.0 0.8982560666317541 10 P42892,P20020,Q93063 3 +Regulation of dendrite development 0.3406343471274657 0.4552691052285522 0.6489156498268402 1.0 0.8991184084091864 21 Q9UQB8,Q86X55,Q12834,Q8WWV3,Q96PU5,Q08209,P49841 7 +Regulation of protein targeting to membrane 0.3960767040033002 0.4519145121669983 0.6513305693925346 1.0 0.9007289412624966 11 P31751,Q00535,P27105,Q9Y3D6 4 +Regulation of reactive oxygen species metabolic process 0.3078731079437945 0.4514167923270646 0.6516891828386968 1.0 0.9009020918518036 33 P39210,Q9BSK2,P00403,P52789,Q8IXJ6,Q9H300 6 +Regulation of long term neuronal synaptic plasticity 0.5234815278647468 0.4502766141545297 0.6525109992696929 1.0 0.9013983323956144 4 Q15334,P21359,P20339 3 +Regulation of nucleotide biosynthetic process 0.4079571366672349 0.4472219982649856 0.6547147796049781 1.0 0.9031852753752057 9 Q15118,Q8NFG4,P00403 3 +Centrosome separation 0.5225908347664657 0.4470237237635206 0.6548579308403228 1.0 0.9031852753752057 4 P43487,P52732 2 +Positive regulation of ossification 0.5008452542166348 0.4458838082830045 0.6556811788636132 1.0 0.903480504236248 5 Q4KMQ2 1 +Regulation of vacuole organization 0.3867998353509904 0.4438399479704867 0.657158304101745 1.0 0.9049209668396796 12 Q9Y371,Q14108 2 +Locomotory behavior 0.3129537000868097 0.4426882497926511 0.6579912426607843 1.0 0.9056825441302844 31 P50897,O75844,O15118,Q8N2K0,Q9NWW5 5 +Response to ischemia 0.4007698021655438 0.4420887961934358 0.6584249514884757 1.0 0.9060611540597624 10 P52789 1 +Fatty acyl coa metabolic process 0.3696607588121668 0.441921098749081 0.6585463023326827 1.0 0.9060611540597624 14 P50897,Q9NZ01,Q53GQ0 3 +Plasma membrane to endosome transport 0.5203506574827798 0.4388720547461031 0.6607542465463725 1.0 0.9084418980808204 4 P51148,Q99523,P61020 3 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.5972557933451974 0.4363467198886537 0.6625851895109509 1.0 0.9089129602617368 3 P04439 1 +Cellular component maintenance 0.4053199614446285 0.4337851444332216 0.664444470270487 1.0 0.909190543808167 9 Q9BRK5 1 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.4102801215086332 0.4295907331959981 0.6674933791860991 1.0 0.9111765537737724 8 O43681,Q99442,Q9UGP8,P61619 4 +Negative regulation of immune response 0.3383455860925703 0.4275840961076141 0.6689539468264729 1.0 0.9111765537737724 20 P09601 1 +Positive regulation of receptor recycling 0.4960376798440832 0.4272971888264967 0.66916288011229 1.0 0.9111765537737724 5 P42892 1 +Ribonucleoprotein complex disassembly 0.5169067000626287 0.4264243631076878 0.6697986517644996 1.0 0.9116586486266752 4 Q14562,Q07866,P55072 3 +Regulation of defense response 0.27795916378386 0.4216778287249429 0.6732601896281123 1.0 0.914324076543804 86 O43657,Q8NCG7,Q08722,Q8N2K0,P15151,Q13546,Q8WXF1,O75844,Q7Z434,Q9NZ08,P11279,Q969V5,Q14166,Q8IXJ6,P04439,Q99735,Q8IZ81,P04062,P53634 19 +Immune response to tumor cell 0.4944341400531878 0.4211426701445639 0.6736509046512904 1.0 0.9145938021613492 5 P04439,P15151 2 +Cellular carbohydrate metabolic process 0.2880593769612938 0.4172537353344094 0.6764928245764439 1.0 0.9169134158447632 63 O43505,P46020,P31751,Q93063,P15291,O75844,Q10713,Q15118,Q9Y6N1,P08236,Q14108,P10253,Q9NX62,Q92520,P52789,Q9H5K3,P49841,Q7LGA3 18 +Fatty acyl coa biosynthetic process 0.3895122436067159 0.4162745334879622 0.6772091254118524 1.0 0.9173434772604496 11 P50897,Q9NZ01,Q53GQ0 3 +Positive regulation of oxidative stress induced cell death 0.5127624626365459 0.4115849260206494 0.6806436821023072 1.0 0.9201637501483584 4 Q13546,Q07820 2 +Regulation of establishment of protein localization 0.2647900680044064 0.4108467370766926 0.6811849201584419 1.0 0.9203817960888176 140 Q92544,P50402,Q8NBM4,P40939,Q7Z3B4,Q9Y371,P51572,Q16850,Q9H4A6,Q9Y282,Q16836,Q9H300,P98194,O14966,P49755,Q96KC8,Q32P28,Q9NR31,P04035,Q8N5M9 20 +Mammary gland epithelium development 0.4915672849971796 0.41019712639501 0.6816613486952876 1.0 0.9208332808924862 5 Q99623,Q9NQC3 2 +Flavin containing compound metabolic process 0.5406758448059956 0.4070665306285009 0.6839591245806633 1.0 0.9229853865681166 2 P55072 1 +Cellular response to xenobiotic stimulus 0.3263975566726908 0.4070550734520121 0.6839675392429987 1.0 0.9229853865681166 25 O43169,P27544,P16435,P07099,Q6PIU2 5 +Mononuclear cell differentiation 0.2919498046721575 0.405797199306121 0.6848916166846089 1.0 0.9231287911851256 42 O96005,P24390 2 +Morphogenesis of a branching structure 0.3361193156610709 0.4056071026696803 0.6850313092552647 1.0 0.9231287911851256 17 Q99623,Q9NQC3 2 +Insulin secretion involved in cellular response to glucose stimulus 0.4631133262074662 0.4051632510159123 0.6853575157052731 1.0 0.9231287911851256 6 Q8N5M9,O95563 2 +Regulation of insulin secretion involved in cellular response to glucose stimulus 0.4631133262074662 0.4051632510159123 0.6853575157052731 1.0 0.9231287911851256 6 Q8N5M9,O95563 2 +Negative regulation of dendritic spine development 0.5397371714643225 0.4038465260483928 0.6863255808002453 1.0 0.9234717586152308 2 Q05086 1 +Eyelid development in camera type eye 0.5397371714643182 0.4038465260483777 0.6863255808002564 1.0 0.9234717586152308 2 Q13547 1 +Cardiac muscle cell contraction 0.3864614960186032 0.39986371657986 0.6892568977435802 1.0 0.9241497083481358 11 Q96PU5,P05023,P16615 3 +Centriole centriole cohesion 0.5856025039123703 0.398659480518806 0.6901441278371498 1.0 0.9245422950589886 3 Q9Y496,P35222 2 +Regulation of long term synaptic potentiation 0.487599893501876 0.3951750316330886 0.6927137181113698 1.0 0.9259823200065882 5 P49841,Q92542,Q13501 3 +Positive regulation of defense response 0.292973061257037 0.3923278539455027 0.6948159855211031 1.0 0.9276888957103 39 Q99735,Q9NUD5,Q8WXF1,P11279,Q13546,P23246,Q7Z434,Q08722,P53634,P26583,P33527,P15151,O94826 13 +Response to nutrient 0.3263721158742464 0.3903506183404162 0.6962772980447285 1.0 0.9281575407875826 24 P09601,Q8TB36,P16435,O15228,P20020 5 +Oogenesis 0.3338810231362991 0.3903055047055045 0.6963106532945695 1.0 0.9281575407875826 17 Q96RD7,Q8N2A8,Q8IXJ6,Q9Y2W6 4 +Aggrephagy 0.4860866864156915 0.3894847303389048 0.6969176041145764 1.0 0.9284583643123792 5 Q5T8D3 1 +Pigment biosynthetic process 0.3257980310200501 0.3859296289771413 0.699548786566446 1.0 0.9306227639584868 24 Q9P0S9,Q7KZN9,P22830,P36551,O00264 5 +Lysosomal transport 0.2915948994074068 0.3855092939697936 0.6998601220074898 1.0 0.9307994863315154 40 O15118,P07602,Q9UNK0,Q14108,Q6IQ22,Q9NZJ7,P11279 7 +Cellular response to biotic stimulus 0.2976357577507777 0.3853619522575935 0.6999692676105509 1.0 0.9307994863315154 34 P11802,Q96A33,O75844,Q86UE4,Q9UM00,Q8IXJ6,P08670,Q8WTV0,O43823 9 +Heart process 0.2939092856333123 0.3811223666374453 0.7031124515053135 1.0 0.933531320010225 35 P23634,Q93063,P78417,O75844,P05023,P17302,Q6PI78,Q96PU5,P20020,P16615 10 +Skeletal muscle cell differentiation 0.3947910410865312 0.3808402318884125 0.7033218041362572 1.0 0.933531320010225 9 Q8NC56,P50402 2 +Regulation of blood circulation 0.3055730979264094 0.3767965945465734 0.7063247717003969 1.0 0.9365568372147036 31 P42892,P78417,O75844,P05023,P17302,Q6PI78,P20020,P16615 8 +Response to ionizing radiation 0.3026840558356393 0.3759094430517616 0.7069842200055354 1.0 0.9372392199663716 32 O60858 1 +Nucleoside phosphate biosynthetic process 0.2646946781118678 0.3755294371182571 0.7072667579788718 1.0 0.937421760728908 98 P50897,P00846,P43490,O75964,P00403,P56385,Q8TB61,P24539,P36542,Q6Y1H2,Q53GQ0,Q9NZ01,Q8WVC6 13 +Regulation of cellular response to osmotic stress 0.4816559564609497 0.3729518107969133 0.7091843099010222 1.0 0.9390018113092092 5 Q9BPX6 1 +Mitochondrial translation 0.2856813594327921 0.3710275738336635 0.710616994255086 1.0 0.9407063176148326 45 Q9Y2R0,Q567V2 2 +Positive regulation of glucose transmembrane transport 0.4804294035667336 0.3684096003858318 0.7125678400300026 1.0 0.9424657119383052 5 Q9BZF1,P31751 2 +Programmed cell death 0.2514377459412373 0.3629236545557959 0.7166619159778089 1.0 0.944240074730766 405 P14174,Q9NQC3,Q07820,Q99720,O95197,P24390,P12236,Q9HCL2,Q96A26,Q15392,Q9BVC6,P07196,Q8WUK0,P45880,Q4KMQ2,O95470,Q15041,Q13144,P50897,P46379,Q9NQX7,Q9H8M7,P09601,Q9Y371,Q9UDX5,P51572,O75844,O60313,Q9Y241,P12235,Q9NS69,Q9P0J0,O75340,O15269,P21796,Q3ZCQ8,Q15118,Q9H4A6,Q9H3K2,Q96KA5,Q9H300,P11279,Q8N2F6,Q14155,Q8IWB1,Q9BXK5,Q658P3,Q99623,Q86XL3,Q969V5,Q9UHX1,Q86UE4,Q9NZJ7,Q8IXJ6,Q9NVI7,P52789,Q9UMX0,P31751,P04062,P51812,P55061,O14681,P15291,P05141,Q96TC7,Q12981,Q13510,P16435,Q01105,Q9Y6C9,Q9NR28 71 +Interferon beta production 0.379452434067935 0.3625596900426258 0.7169338268274079 1.0 0.944240074730766 11 P41440,Q7Z434,O94826 3 +Positive regulation of interferon beta production 0.379452434067935 0.3625596900426258 0.7169338268274079 1.0 0.944240074730766 11 P41440,Q7Z434,O94826 3 +Metencephalon development 0.3038514437395199 0.3615593688530383 0.7176813321880708 1.0 0.9448400288692422 31 Q7Z4L5,P04062,O15020,O14949,P18887,O15228,Q9BRK5 7 +Protein import 0.2736037587079672 0.3601138445611744 0.7187619999311992 1.0 0.9452470475877258 86 Q92973,Q99595,Q9Y5L0,Q8NFH5,Q9Y512,Q7Z3B4,O94826,P40855,P13473,Q7Z434,Q3ZCQ8,Q9NS69,P56589,P55735,Q8TEX9,Q99623,O95831,Q7Z4Q2,O75381,O96008,O14925,O43615,Q96DA6,Q15388,Q08209 25 +Receptor diffusion trapping 0.5265957446808391 0.3598886768581794 0.7189303850387416 1.0 0.9452470475877258 2 Q9NQX3 1 +Neurotransmitter gated ion channel clustering 0.5265957446808391 0.3598886768581794 0.7189303850387416 1.0 0.9452470475877258 2 Q9NQX3 1 +Regulation of cardiac muscle adaptation 0.5730143895508275 0.3593300560146304 0.7193481922690088 1.0 0.9452470475877258 3 P23634 1 +Fatty acid derivative biosynthetic process 0.363963198015133 0.3591925987422477 0.7194510130434391 1.0 0.9452470475877258 13 P50897,Q9NZ01,Q53GQ0 3 +Positive regulation of reactive oxygen species biosynthetic process 0.4969303498700941 0.3563879367939552 0.7215500621543858 1.0 0.9475870673734518 4 P00403 1 +Cell junction maintenance 0.4508145363408627 0.3556246091789355 0.7221217114647334 1.0 0.9477892753621564 6 Q15334,Q14203,Q07157,Q96AC1,Q9BRK5 5 +Positive regulation of endothelial cell proliferation 0.3708798569964427 0.3552710175227514 0.7223865657485913 1.0 0.9477892753621564 12 P09601 1 +Angiogenesis involved in wound healing 0.4963904256728966 0.3545495853796763 0.7229270504279481 1.0 0.9479210934585168 4 P15291 1 +Caveolin mediated endocytosis 0.4960951030968501 0.3535453425242871 0.7236796422155587 1.0 0.9483270689824828 4 Q96PU5 1 +Regulation of action potential 0.3830857714670319 0.3506062449710375 0.7258837707963348 1.0 0.9493267393164168 10 P16615 1 +Ire1 mediated unfolded protein response 0.4489775603841461 0.3483600261931087 0.7275698190698567 1.0 0.949786941969839 6 P57088,Q92905 2 +Regulation of endoplasmic reticulum tubular network organization 0.4489543519910617 0.3482684795187679 0.7276385635319538 1.0 0.949786941969839 6 P57088,Q15041 2 +Neurotransmitter secretion 0.3259698655200445 0.3482393454032189 0.727660441456059 1.0 0.949786941969839 21 P50897,Q4J6C6,Q7L0J3,P49841,P16615 5 +Regulation of intrinsic apoptotic signaling pathway 0.2819431947175808 0.3468771421190627 0.7286836196543913 1.0 0.9500809727386472 55 Q8N2F6,P14174,Q07820,P51572,P55061,O60313,P23246,Q8WUK0,Q9P0J0,P45880,Q8NFG4,P61978,Q9H300,Q9UMX0 14 +Positive regulation of nf kappab transcription factor activity 0.3139972189086238 0.3462921204189578 0.72912318971852 1.0 0.9501098446177716 27 Q86UE4,O60858 2 +Telencephalon development 0.2843270322887186 0.3459059377586785 0.7294134061162005 1.0 0.9501098446177716 44 Q96QD8,Q9NQC3,P23634,P07196,O14949,P18887,Q96N66,O94901,P49841,Q13144 10 +Regulation of phospholipid metabolic process 0.3758115979729002 0.3434177156649438 0.7312842338465801 1.0 0.9501098446177716 11 Q8NF37,Q8WTV0 2 +Regulation of cell activation 0.2818662382601493 0.3426321606781776 0.7318752043036143 1.0 0.9501098446177716 63 P09601,Q9HCL2,Q9BWH2,Q08722,O96005,P30825 6 +Dendrite extension 0.4733725960279794 0.3425786443266545 0.73191547027217 1.0 0.9501098446177716 5 Q969V5 1 +Negative regulation of muscle organ development 0.5674844670468175 0.3425351685034313 0.7319481822408571 1.0 0.9501098446177716 3 Q8IXJ6 1 +Retina morphogenesis in camera type eye 0.4732887942585387 0.3422750588113787 0.73214390348996 1.0 0.9501098446177716 5 Q16706,Q15555,Q8NBN7 3 +Ribose phosphate biosynthetic process 0.2729663238896391 0.3422563405855283 0.7321579888144121 1.0 0.9501098446177716 85 P50897,P00846,O75964,P00403,P56385,Q8TB61,P24539,P36542,Q6Y1H2,Q53GQ0,Q9NZ01,Q8WVC6 12 +Regulation of sequestering of triglyceride 0.5670899096537508 0.3413485334064641 0.732841215131631 1.0 0.9501098446177716 3 Q9BZF1 1 +Sequestering of triglyceride 0.5670899096537508 0.3413485334064641 0.732841215131631 1.0 0.9501098446177716 3 Q9BZF1 1 +Epidermis development 0.2828090795251823 0.3405417997195011 0.7334485500689218 1.0 0.9502109507424424 45 Q16739,O75844,P51648,Q13510,P98194,P16615 6 +Positive regulation of glucose import 0.4919827746387655 0.3396566659316728 0.7341150990858365 1.0 0.9506188317894224 4 Q9BZF1,P31751 2 +Regulation of phagocytosis 0.3441347884931349 0.338741317120916 0.7348046122884229 1.0 0.950834873985078 15 Q8WTV0,Q08722 2 +Positive regulation of potassium ion transmembrane transporter activity 0.565571205007823 0.3367957306565066 0.7362708916936529 1.0 0.9520769652430212 3 P50570,P54709 2 +Regulation of dendrite extension 0.4904556740178439 0.3345450661578412 0.7379682899770597 1.0 0.952939100704615 4 Q969V5 1 +Response to monosaccharide 0.3067525051155267 0.3316545086558962 0.7401501549307481 1.0 0.9529554653679608 29 P62995,Q9HCL2,P49770,Q15043,Q8N5M9,Q08209,O95563,Q13144 8 +Neural retina development 0.384727259233512 0.3314053696172208 0.7403383094852789 1.0 0.9529554653679608 9 P20020,Q8NBN7 2 +Positive regulation of endothelial cell migration 0.3257306051543199 0.3309395017950576 0.7406901834295812 1.0 0.9529554653679608 19 P09601,Q8WTV0 2 +Organophosphate catabolic process 0.2917752437722586 0.330525656174681 0.7410028100674408 1.0 0.9529554653679608 34 P49902,Q9NXE4,P35610,Q10713,Q9NX62,Q8N2K0,Q8WTV0 7 +Purine containing compound biosynthetic process 0.2752633660625284 0.3304397060328961 0.7410677437595146 1.0 0.9529554653679608 79 P50897,P00846,O75964,P00403,P56385,Q8TB61,P24539,P36542,Q6Y1H2,Q53GQ0,Q9NZ01,Q8WVC6 12 +Torc1 signaling 0.4438603560272806 0.3283195053994239 0.7426700976676377 1.0 0.9529554653679608 6 Q9P2J5,P42345,Q8NFG4 3 +Plus end directed organelle transport along microtubule 0.5165832290362822 0.327872994415677 0.743007693380918 1.0 0.9529554653679608 2 Q9Y496 1 +Anterograde dendritic transport 0.5165832290362823 0.327872994415677 0.743007693380918 1.0 0.9529554653679608 2 Q14254 1 +Dense core granule transport 0.5165832290362823 0.327872994415677 0.743007693380918 1.0 0.9529554653679608 2 Q12756 1 +Anterograde neuronal dense core vesicle transport 0.5165832290362823 0.327872994415677 0.743007693380918 1.0 0.9529554653679608 2 Q12756 1 +Fatty acid beta oxidation 0.2878355362538849 0.3265205486137449 0.7440305449412064 1.0 0.9529554653679608 36 P28288,P31751,O43808,Q16134,O14975,P35610,O14678,O15254,P50416,Q15067,Q709F0,P23786,P40939,Q16836 14 +Response to angiotensin 0.5159574468085016 0.325916339273602 0.7444876531413649 1.0 0.9529554653679608 2 Q05655 1 +Regulation of ire1 mediated unfolded protein response 0.468412171756533 0.3247409112547834 0.7453771685860198 1.0 0.9529554653679608 5 P57088,Q92905 2 +Negative regulation of alcohol biosynthetic process 0.5614260973212893 0.3244896947848601 0.7455673229330082 1.0 0.9529554653679608 3 Q12770 1 +Negative regulation of cholesterol metabolic process 0.5614260973212893 0.3244896947848601 0.7455673229330082 1.0 0.9529554653679608 3 Q12770 1 +Antigen processing and presentation of exogenous antigen 0.4428649826122222 0.324455703509516 0.7455930532839403 1.0 0.9529554653679608 6 Q9UIQ6 1 +Centromeric sister chromatid cohesion 0.4426691729323417 0.3236969607374519 0.7461674720612974 1.0 0.9530455440387098 6 P35222,P49711,Q9GZZ1,O60566,P41227 5 +Unsaturated fatty acid biosynthetic process 0.3718750433963702 0.322915419599696 0.7467592982349753 1.0 0.9534476579555652 11 Q8NCG7,O00767 2 +Small molecule biosynthetic process 0.2598575009288293 0.3224058142364192 0.747145280077973 1.0 0.9536582272678846 140 P14324,P14174,Q13126,O00767,Q15392,Q9H7Z7,Q8NCG7,Q14739,Q15800,P55263,Q16850,O15269,Q9P035,Q53GQ0,Q92520,Q9NZ01,Q86SQ9,Q9UBX3,P23634,O75845,P00367,Q6Y1H2,Q8NI60,Q15043,P37268,Q92604,Q9H1P3,Q12770,Q99735,Q9UBM7,P04062,A1L0T0,Q13510,P04035,P16435,P09960 36 +Positive regulation of protein neddylation 0.5604880813469122 0.3217296230459757 0.7476575341235452 1.0 0.9538418215745288 3 Q96GG9 1 +Oocyte construction 0.5600329342043675 0.3203936924583669 0.7486699064401612 1.0 0.9540542057852957 3 Q8N2A8 1 +Positive regulation of phagocytosis 0.3873284637564695 0.3196545936962481 0.7492301840853195 1.0 0.9543578578456368 8 Q08722 1 +Synaptonemal complex organization 0.4415131547966727 0.3192265734451119 0.7495547076031222 1.0 0.9544061729269206 6 Q92791 1 +Purine containing compound metabolic process 0.2597647405353789 0.3192003866129646 0.7495745638114242 1.0 0.9544061729269206 139 P49902,Q9HCL2,Q9BRR6,P50897,P00403,P35610,P24539,Q53GQ0,Q9NZ01,O75964,P56385,O60725,Q6Y1H2,P52789,Q8WVC6,P00846,Q8IWA4,P56134,Q8TB61,Q86UL3,P36542,P04035 22 +Sarcoplasmic reticulum calcium ion transport 0.370993379725397 0.3183523709607351 0.7502176627123021 1.0 0.9544912438142344 11 O75844 1 +Fatty acid beta oxidation using acyl coa oxidase 0.4664637976186456 0.3178094605953732 0.7506294739712909 1.0 0.954622510422911 5 Q15067 1 +Regulation of endoplasmic reticulum unfolded protein response 0.4137686751424611 0.3172588240176274 0.7510472183424723 1.0 0.9549661290987193 7 P57088,Q92905,O76024 3 +Regulation of gtp binding 0.4407459901145133 0.3162685188137926 0.7517987040430327 1.0 0.955358573054488 6 O75503 1 +Response to hydrogen peroxide 0.3164741841532229 0.3148869537350341 0.7528474875141284 1.0 0.9561916646499208 24 P09601,Q99720 2 +Endoplasmic reticulum localization 0.5580594679186307 0.3146264965964742 0.753045258764006 1.0 0.9561916646499208 3 A0FGR8,Q9BSJ8 2 +Endoplasmic reticulum plasma membrane tethering 0.5580594679186307 0.3146264965964742 0.753045258764006 1.0 0.9561916646499208 3 A0FGR8,Q9BSJ8 2 +Prostanoid biosynthetic process 0.3861654670697633 0.3142520802822531 0.7533295902969956 1.0 0.9562288810882894 8 Q9H7Z7,Q8NCG7 2 +Cerebral cortex development 0.3045372147571495 0.3131319206248807 0.754180438527384 1.0 0.9568821403938892 29 Q96N66,O94901,Q9NQC3 3 +Negative regulation of multicellular organismal process 0.2564604164085485 0.3120288678392318 0.7550185844562058 1.0 0.957032899207132 102 Q9NQC3,Q9UIQ6,P09601,Q16850,Q96G23,P17302,P20020,Q8N0X7,P23634,Q99623,Q969V5,P57105,Q8IXJ6,P49841,P16615,O43823,P04062,P05023,Q92945,Q8NFG4,P04035,P53634 22 +Positive regulation of protein secretion 0.3220589389304786 0.311952729239667 0.7550764484241661 1.0 0.957032899207132 20 Q9NV70,P49755,Q9Y5U9,Q8IWT6,O95486,P00367,Q9H4A6,O95563 8 +Error free translesion synthesis 0.5112640801001118 0.3114121756289817 0.7554872989565358 1.0 0.957032899207132 2 Q9Y2S7 1 +Activation of immune response 0.2789884506606692 0.3112515028689622 0.7556094324480664 1.0 0.957032899207132 46 Q07666,O14966,P00813,Q9NUD5,Q8WXF1,Q99623,Q14699,P23246,P09429,Q7Z434,O94826,P49770,Q08722,P04439,P46379,Q13144 16 +Nucleobase containing compound transport 0.2568665527894809 0.3102265883633037 0.7563886526742021 1.0 0.957032899207132 109 Q8NFH5,Q08J23,P51991,P12236,Q07955,Q9HC21,Q08722,Q7Z3B4,Q13546,Q07666,P41440,P12235,Q8TDW0,Q86VD7,Q9BTX1,Q9H2D1,O15504,P22626,Q12769,Q9BSK2,P67809,P41208,Q6NUK1,O43808,Q9Y6M1,Q14699,Q8TB61,P05141,Q92945,L0R6Q1 30 +Negative regulation of protein localization to cell surface 0.4830307406809603 0.3100573384340514 0.7565173535759713 1.0 0.957032899207132 4 Q96PU5 1 +Acute inflammatory response 0.4642046194317949 0.3098264978358564 0.7566929000944365 1.0 0.9570679009988652 5 Q4KMQ2,P15291 2 +Maternal process involved in female pregnancy 0.4638590783913721 0.3086106960979289 0.7576176834742152 1.0 0.9576468405120028 5 P35613 1 +Regulation of endothelial cell migration 0.3067139725340861 0.308258313099962 0.7578857838286734 1.0 0.9576468405120028 28 P09601,P57105,Q8WTV0 3 +Negative regulation of calcium ion transmembrane transport 0.3845152295227126 0.3066170487092161 0.7591348753406595 1.0 0.9583658566197216 8 P21796,Q9UMX0 2 +Neuromuscular process controlling balance 0.3685687489949628 0.305859930665068 0.7597112954766059 1.0 0.9584795971306042 11 O14773 1 +B cell differentiation 0.3684431315658756 0.3052149937268043 0.7602024135641896 1.0 0.9584795971306042 11 P04637,P00813,Q8IWT6,P05141,P55327,P05556 6 +Receptor metabolic process 0.2918675721075444 0.3040586968263938 0.7610831730995629 1.0 0.9588990182449506 33 P41440,Q8NBU5,Q8IZ07,P42892,Q9Y371,Q13636,P49354,O14966 8 +Protein stabilization 0.2761521599186588 0.3035399853747719 0.7614783799801086 1.0 0.9588990182449506 73 P41440,P40855,Q9UNS2,Q9NQC3,O75718,Q969V3,Q86Y82,P13473,Q99623,Q969V5,O75569,Q9UBV2,Q32P28,Q96JB2,P11279,P46379,O15027 17 +Detection of light stimulus 0.4621650920504939 0.3026704761227268 0.7621409996681128 1.0 0.9588990182449506 5 Q13432 1 +Negative regulation of cytokine production 0.3162777965998445 0.3009173174249713 0.763477544611852 1.0 0.9592088160992532 23 P09601,Q969V5 2 +Protein mannosylation 0.5532730681245934 0.3008114763654827 0.7635582566297061 1.0 0.9592088160992532 3 O43505 1 +Protein o linked mannosylation 0.5532730681245934 0.3008114763654827 0.7635582566297061 1.0 0.9592088160992532 3 O43505 1 +Cellular response to topologically incorrect protein 0.2840972736141948 0.2990289251928157 0.7649179756078985 1.0 0.9595262491225528 38 Q96HE7,P57088,P48723,P55061,Q92905,Q9UKV5,Q9GZP9,Q7Z2K6,Q15363,Q9Y4P3,Q6NTF9,P46379 12 +Regulation of response to external stimulus 0.2583956690344413 0.2987596006475729 0.7651234778397917 1.0 0.9595262491225528 122 Q99735,O43657,P04062,O75844,Q969V5,Q96G23,Q11206,Q13641,Q8NCG7,Q08722,Q8IXJ6,Q4KMQ2,P80303,P11279 14 +Phagosome lysosome fusion 0.5068836045056219 0.2981512412885246 0.7655877340479482 1.0 0.9595262491225528 2 P51149 1 +Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii 0.5068836045056186 0.298151241288515 0.7655877340479555 1.0 0.9595262491225528 2 P50570 1 +Female meiosis i 0.4790231684408245 0.2970996242293697 0.7663904512467239 1.0 0.9595262491225528 4 Q15645,O14965,O95067 3 +Meiotic spindle assembly 0.4790231684408237 0.2970996242293668 0.7663904512467261 1.0 0.9595262491225528 4 Q08379,O14965,O95067 3 +Regulation of inflammatory response 0.2848923615439727 0.2954105139651706 0.7676803025272834 1.0 0.9595262491225528 35 P04062,Q08722,Q99735,Q8NCG7 4 +Amyloid beta clearance 0.3769269569740213 0.2939818999794584 0.7687717342877289 1.0 0.9595931850164284 9 P04035 1 +Regulation of blood brain barrier permeability 0.504693366708373 0.2916226280570496 0.7705751724197807 1.0 0.9600028117075812 2 Q9UDY2 1 +Positive regulation of blood brain barrier permeability 0.504693366708373 0.2916226280570496 0.7705751724197807 1.0 0.9600028117075812 2 Q9UDY2 1 +Positive regulation of vascular permeability 0.504693366708373 0.2916226280570496 0.7705751724197807 1.0 0.9600028117075812 2 Q9UDY2 1 +Maintenance of location in cell 0.2790956458687361 0.2914341965803843 0.7707192639407803 1.0 0.9600028117075812 44 Q96HE7,O43731,P78417,P24390,O43292,O95202,Q9H4A6,Q9UH99,O15258,P52789,O94901,Q00535 12 +Positive regulation of proteolysis 0.2644407585617136 0.2906423334203361 0.7713248796167216 1.0 0.9600028117075812 92 Q96A26,Q12797,P46379,P51572,Q12834,Q9P0J0,O75340,Q6ZXV5,Q9BXK5,Q4ZIN3,Q969V5,Q9NZJ7,Q8IXJ6,O95831,O00487,P49841,Q9UMX0,O75915,Q9Y3D6,P04062,P43686,P53634,Q9NWW5,Q9NR28 24 +Negative regulation of keratinocyte proliferation 0.5040675844805871 0.2897699208437375 0.7719922607323713 1.0 0.960464035267187 2 O14936 1 +Lipid import into cell 0.4336535181843961 0.2892554709571878 0.7723858854590309 1.0 0.9606358104040162 6 P31751,O14975 2 +Positive regulation of response to wounding 0.3802696481361274 0.2871455020882382 0.7740009128394889 1.0 0.962038392144646 8 Q11206 1 +Microtubule anchoring 0.3647663802612477 0.286440497564475 0.77454076090265 1.0 0.9622850281291918 11 Q15154,O75381,P49841,Q9P287 4 +Potassium ion transport 0.3181002194898343 0.2845148981238506 0.7760158185389094 1.0 0.9630177986062756 20 Q9NUT2,P05023,Q96PU5,Q9BXP2,P54709,Q4KMQ2 6 +Positive regulation of protein localization to cell periphery 0.3180598400011188 0.284368410191741 0.7761280651313864 1.0 0.9630177986062756 17 O00264,O15258 2 +Cellular response to dsrna 0.3642768875154818 0.2839562452744146 0.7764439121823978 1.0 0.963040436880889 11 P41440,Q969V5 2 +Negative regulation of defense response 0.2946950298642419 0.2815271041412471 0.778306142277845 1.0 0.9644062014145702 31 Q969V5,O43657 2 +Nucleus localization 0.3425695956739768 0.2813537059321487 0.7784391217845665 1.0 0.9644062014145702 14 Q5SNT2,Q15154,P42345,Q9UH99,O94901 5 +Intrinsic apoptotic signaling pathway 0.2701537277978776 0.2804178328274193 0.7791569570457235 1.0 0.9646813221946966 82 P14174,Q07820,Q9BVC6,Q8WUK0,P45880,P61978,P46379,P09601,P51572,O60313,P23246,O75569,Q9P0J0,Q15118,Q9H300,Q8N2F6,O95831,Q9UMX0,Q96HE7,O75915,Q9Y3D6,P55061,Q8NFG4,Q9NR28 24 +Positive regulation of endocytosis 0.3163245490109805 0.2797122872714647 0.7796982506028276 1.0 0.9646813221946966 21 P41440,P50897,Q4KMQ2,Q96PU5 4 +Cell volume homeostasis 0.4041869648155732 0.2773029057162142 0.7815475285832851 1.0 0.9663907633724206 7 Q9NUT2,Q4KMQ2,Q9BXP2,P51790 4 +Positive regulation of striated muscle cell differentiation 0.4541183839649377 0.2749221978870054 0.783376012585189 1.0 0.9669044426469794 5 Q9UGN5,Q15014,Q16539,P42345 4 +Detection of cell density 0.4987484355444232 0.2742509427505648 0.7838917816082525 1.0 0.9669044426469794 2 Q13153 1 +Germinal center formation 0.4987484355444167 0.2742509427505466 0.7838917816082664 1.0 0.9669044426469794 2 P00813 1 +Regulation of germinal center formation 0.4987484355444167 0.2742509427505466 0.7838917816082664 1.0 0.9669044426469794 2 P00813 1 +Regulation of keratinocyte migration 0.5434386433311209 0.2732150639055021 0.7846879010272836 1.0 0.9671491326316092 3 P42345 1 +Keratinocyte migration 0.5434386433311209 0.2732150639055021 0.7846879010272836 1.0 0.9671491326316092 3 P42345 1 +Regulation of myotube differentiation 0.4291979949874783 0.2726054854051303 0.7851564948573979 1.0 0.96754242854476 6 P42345,Q96TA1,Q16539,Q13547,Q8NEZ5 5 +Fibroblast migration 0.3406525643558629 0.2704084590871629 0.7868460330207216 1.0 0.9687449955867276 14 O95470,Q5SNT2 2 +N acetylneuraminate metabolic process 0.4696305572949223 0.2674759774943271 0.7891027077727886 1.0 0.9687449955867276 4 Q8NFW8,Q9UJ70,Q9Y223 3 +Cellular response to lipoprotein particle stimulus 0.4695804618649448 0.2673208609236644 0.7892221263279415 1.0 0.9687449955867276 4 O15118 1 +Negative regulation of transmembrane transport 0.3154800468576216 0.2665216442358145 0.7898374923526572 1.0 0.9687449955867276 20 P31751,P78417,Q96PU5,P21796,Q9UMX0 5 +Autophagosome lysosome fusion 0.4959324155193857 0.2662030157509906 0.7900828605669337 1.0 0.9687449955867276 2 Q9NVJ2 1 +Vesicle mediated cholesterol transport 0.4959324155193857 0.2662030157509906 0.7900828605669337 1.0 0.9687449955867276 2 Q9NVJ2 1 +Hyperosmotic salinity response 0.4515108718022909 0.2661016252744959 0.7901609433265304 1.0 0.9687449955867276 5 Q9BPX6 1 +Cellular response to salt stress 0.4515108718022909 0.2661016252744959 0.7901609433265304 1.0 0.9687449955867276 5 Q9BPX6 1 +Cellular hyperosmotic salinity response 0.4515108718022909 0.2661016252744959 0.7901609433265304 1.0 0.9687449955867276 5 Q9BPX6 1 +Lipophagy 0.4514684715216358 0.2659589054484801 0.7902708581842435 1.0 0.9687449955867276 5 O15269 1 +Calcineurin mediated signaling 0.4012622075206408 0.265351624811338 0.7907385985144799 1.0 0.9687449955867276 7 Q08209,P23634,P49841 3 +Inositol phosphate mediated signaling 0.4012622075206408 0.265351624811338 0.7907385985144799 1.0 0.9687449955867276 7 Q08209,P23634,P49841 3 +Fungiform papilla development 0.5399061032863927 0.263569019328479 0.7921120335702865 1.0 0.9687449955867276 3 Q13547,P35222 2 +Tongue morphogenesis 0.5399061032863927 0.263569019328479 0.7921120335702865 1.0 0.9687449955867276 3 Q13547,P35222 2 +Hair follicle placode formation 0.5399061032863927 0.263569019328479 0.7921120335702865 1.0 0.9687449955867276 3 Q13547,P35222 2 +Ectodermal placode development 0.5399061032863927 0.263569019328479 0.7921120335702865 1.0 0.9687449955867276 3 Q13547,P35222 2 +Tongue development 0.5399061032863927 0.263569019328479 0.7921120335702865 1.0 0.9687449955867276 3 Q13547,P35222 2 +Fungiform papilla morphogenesis 0.5399061032863927 0.263569019328479 0.7921120335702865 1.0 0.9687449955867276 3 Q13547,P35222 2 +Response to epinephrine 0.4669681191760833 0.2592753327285159 0.7954228104405581 1.0 0.9706453915487828 4 Q8IXJ6 1 +Cellular response to epinephrine stimulus 0.4669681191760833 0.2592753327285159 0.7954228104405581 1.0 0.9706453915487828 4 Q8IXJ6 1 +Bergmann glial cell differentiation 0.4492732123863118 0.2586010217147902 0.7959430948425874 1.0 0.97076476157448 5 Q7Z4L5 1 +Endoplasmic reticulum to cytosol transport 0.3384725780132959 0.25804043212186 0.7963757032338254 1.0 0.9710142334832929 14 P51572,Q9GZP9,Q9UBV2,Q8NBM4 4 +Positive regulation of antigen receptor mediated signaling pathway 0.4645266088504049 0.2518336667189824 0.801169633491531 1.0 0.9726752940852338 4 O14966 1 +Positive regulation of t cell receptor signaling pathway 0.4645266088504049 0.2518336667189824 0.801169633491531 1.0 0.9726752940852338 4 O14966 1 +3 utr mediated mrna stabilization 0.3724137931034529 0.2518012595822403 0.8011946836786745 1.0 0.9726752940852338 8 Q15717,Q13148,P98175,Q16539,Q13151,Q92615,P16989 7 +Membrane raft assembly 0.3975460070353274 0.2503403892148057 0.8023241245258876 1.0 0.9733244851367164 7 P41440,Q14699 2 +Regulation of type b pancreatic cell development 0.5345069456008238 0.2491059815225004 0.8032788026929212 1.0 0.9735618747244544 3 P49841 1 +Interleukin 6 production 0.3506696536061401 0.2476976798086948 0.8043683271849691 1.0 0.973893035814411 12 P04062 1 +Regulation of jun kinase activity 0.3967408335944878 0.2471142443374709 0.8048198101468533 1.0 0.973893035814411 7 Q16512,P23396,Q13153,O43318,P18031,P31689 6 +Histone h4 k12 acetylation 0.4887359198998621 0.2461754308950063 0.8055464337165157 1.0 0.9743032179056792 2 Q8WYH8 1 +Muscle adaptation 0.3127969724539982 0.2433870638345434 0.8077055641310602 1.0 0.9760026906378308 19 P09601 1 +Protein import into peroxisome membrane 0.461206883337845 0.2418376196791762 0.8089059876610698 1.0 0.9767929075531904 4 P40855,P56589 2 +Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway 0.4868585732165066 0.2410802430114363 0.8094929250353378 1.0 0.9769750369906842 2 Q8WUM4 1 +Neuroblast division 0.5312004889545452 0.2404188342205394 0.8100055787267912 1.0 0.9771400010288523 3 P61026 1 +Asymmetric neuroblast division 0.5312004889545452 0.2404188342205394 0.8100055787267912 1.0 0.9771400010288523 3 P61026 1 +Regulation of protein localization to membrane 0.2737763369320942 0.2367792376432472 0.8128280595477142 1.0 0.978902717043693 44 P31751,P23634,Q9BXS4,P27105,O15400,Q9UNK0,O00264,O15258,P98194,Q00535,Q9HD26 11 +Cellular response to vitamin 0.458607410576213 0.2341103174457594 0.8148993363204737 1.0 0.9804762211171032 4 Q8TB36 1 +Negative regulation of extrinsic apoptotic signaling pathway 0.3085208762528101 0.2339029718149561 0.815060306029673 1.0 0.9804762211171032 22 P09601,Q8IWB1 2 +Schwann cell differentiation 0.3682718746614411 0.2335464541683249 0.8153371014725224 1.0 0.9804762211171032 8 P31751,Q8IXJ6 2 +Positive regulation of leukocyte proliferation 0.3340719174431159 0.233339139525348 0.8154980683364288 1.0 0.9804762211171032 14 Q9HCL2 1 +Embryonic digestive tract development 0.4834167709636903 0.2318801533197475 0.8166310998030084 1.0 0.9808105290263412 2 P00813 1 +Genitalia morphogenesis 0.4834167709636904 0.2318801533197472 0.8166310998030086 1.0 0.9808105290263412 2 P35222 1 +Rho protein signal transduction 0.3103652377668025 0.2318102378661043 0.8166854049633734 1.0 0.9808105290263412 20 Q9P035,P57105 2 +Positive regulation of wound healing spreading of epidermal cells 0.4827909887359055 0.2302271525157453 0.8179152638371412 1.0 0.981741021430634 2 P42345 1 +Dna templated transcription termination 0.353262961664771 0.2290695165348444 0.8188148858351147 1.0 0.9818300357056652 11 O75844 1 +Cellular response to potassium ion 0.5267605633802904 0.2289604580388985 0.8188996496815784 1.0 0.9818300357056652 3 P55011,Q14168 2 +Response to potassium ion 0.5267605633802904 0.2289604580388985 0.8188996496815784 1.0 0.9818300357056652 3 P55011,Q14168 2 +Locomotory exploration behavior 0.5267605633802902 0.2289604580388974 0.8188996496815792 1.0 0.9818300357056652 3 Q05086,Q9HB07 2 +Regulation of exit from mitosis 0.4169490539558141 0.2281896323322108 0.819498821042115 1.0 0.9821845129230682 6 Q8IXJ6 1 +Glycosyl compound catabolic process 0.3579020788493738 0.2273393168606829 0.8201599029282958 1.0 0.9826129011018012 10 P04062,P08236,Q9BTY2 3 +Myeloid leukocyte migration 0.3045443409395202 0.2264529538546986 0.8208491461862766 1.0 0.9829809438291351 24 Q8N5M9,Q4KMQ2,Q08722 3 +Regulation of hormone secretion 0.3008997741311744 0.2259406879220496 0.8212475515648259 1.0 0.9831879677631434 26 P50416,Q9BRT2,P00367,P17302,Q08209,Q8N5M9,P40939,Q16836,O95563 9 +Negative regulation of lipid transport 0.5249987403771881 0.2244800989977733 0.8223837505062885 1.0 0.9840021507259566 3 P31751 1 +B cell lineage commitment 0.479974968710882 0.2228643575357373 0.8236410772964828 1.0 0.9845964263507456 2 P04637 1 +Ectopic germ cell programmed cell death 0.4799749687108742 0.2228643575357173 0.8236410772964984 1.0 0.9845964263507456 2 P42575 1 +Programmed cell death involved in cell development 0.4799749687108742 0.2228643575357173 0.8236410772964984 1.0 0.9845964263507456 2 P42575 1 +Medium chain fatty acyl coa metabolic process 0.4793491864830894 0.2212450725650758 0.8249016158725067 1.0 0.9857391539746791 2 P51659 1 +G2 mi transition of meiotic cell cycle 0.4787234042553046 0.2196319539849198 0.8261578033053212 1.0 0.9861875820767466 2 O95067 1 +Schwann cell development 0.3897367169939285 0.2194590712272106 0.8262924591458258 1.0 0.9861875820767466 7 P31751,Q8IXJ6 2 +Adenylate cyclase modulating g protein coupled receptor signaling pathway 0.3315641237397538 0.2194286512791997 0.826316153325177 1.0 0.9861875820767466 14 Q9NZJ7 1 +Regulation of vesicle mediated transport 0.2532856395835735 0.2193935173846194 0.8263435194070143 1.0 0.9861875820767466 119 P50897,P41440,O14966,P09601,Q9NR31,Q13432,P57105,Q96PU5,Q9P2W9,Q08722,P98194,Q4KMQ2,Q8WTV0,P11279,P16615 15 +Amine transport 0.3648948677680569 0.2188678175430143 0.8267530165466304 1.0 0.9864943811006252 8 Q15041 1 +Farnesyl diphosphate metabolic process 0.5220782229936122 0.2171372766210334 0.8281013643647783 1.0 0.987739039839448 3 P37268 1 +Notch signaling pathway 0.3155792382557039 0.2152062560820794 0.8296065135546751 1.0 0.9889875401963266 16 P57105 1 +Positive regulation of epithelial to mesenchymal transition 0.4356404635139427 0.2143357802509378 0.8302852177035063 1.0 0.9893390573239362 5 Q92769,P42345,P35222,Q96AC1 4 +Positive regulation of granulocyte chemotaxis 0.435014093329169 0.2123631564821405 0.8318237270852089 1.0 0.9899895479395868 5 O00429,Q07021,Q8NHP6,Q8NE86 4 +Positive regulation of neutrophil migration 0.435014093329169 0.2123631564821405 0.8318237270852089 1.0 0.9899895479395868 5 O00429,Q07021,Q8NHP6,Q8NE86 4 +Columnar cuboidal epithelial cell differentiation 0.343608144415102 0.2116842352059055 0.8323533878765479 1.0 0.9900873784763126 12 Q9P287,P04818,Q86UL3 3 +Intracellular sterol transport 0.3496311295509254 0.2114224784568877 0.832557617888217 1.0 0.9900873784763126 11 O15118,Q96JX3 2 +Mammary gland epithelial cell proliferation 0.5197167544880078 0.211277385548726 0.8326708283446491 1.0 0.9900873784763126 3 Q9NQC3 1 +Cholesterol efflux 0.3859378673352423 0.2047768012245202 0.8377465128610981 1.0 0.9933511939083792 7 O15118,Q8WTV0 2 +Positive regulation of lymphocyte apoptotic process 0.4727784730913575 0.2046168723010655 0.8378714721176983 1.0 0.9933511939083792 2 P04637 1 +Positive regulation of t cell apoptotic process 0.4727784730913575 0.2046168723010655 0.8378714721176983 1.0 0.9933511939083792 2 P04637 1 +Regulation of phospholipid transport 0.4727784730913573 0.2046168723010649 0.8378714721176987 1.0 0.9933511939083792 2 Q05655 1 +Negative regulation of membrane potential 0.4727784730913494 0.2046168723010459 0.8378714721177136 1.0 0.9933511939083792 2 O75915 1 +Negative regulation of ion transmembrane transport 0.305468804307635 0.2034464913131278 0.8387860647308183 1.0 0.9940713076245844 17 Q96PU5,P21796,Q9UMX0,P78417 4 +Cellular response to interleukin 1 0.3609022298966007 0.2017601537552688 0.8401042335725448 1.0 0.9949047757880164 8 Q08722 1 +Regulation of golgi to plasma membrane protein transport 0.4089044205706595 0.2001733158980344 0.8413450356403525 1.0 0.995842435267651 6 P98194 1 +Negative regulation of intracellular protein transport 0.3348963433488138 0.2001572405148486 0.8413576075468967 1.0 0.995842435267651 13 Q9GZP9,Q8NBM4 2 +Nephron development 0.3204158104221006 0.1981003689340886 0.8429665361860894 1.0 0.9960624373746122 15 P35610,Q12769,P39210 3 +Chromosome organization involved in meiotic cell cycle 0.3203585365875384 0.1977741446554672 0.8432217761609062 1.0 0.9960624373746122 15 Q92791,O94901,Q9BTX1 3 +Thioester metabolic process 0.2771302178493579 0.1970950653229791 0.8437531449909152 1.0 0.9960624373746122 34 P50897,Q9HCL2,Q86UL3,Q6Y1H2,Q53GQ0,Q9NZ01 6 +Cellular response to starvation 0.287655535480236 0.1970316503313563 0.8438027698529136 1.0 0.9960624373746122 30 P04062,Q9Y371,P21964 3 +Regulation of peptide transport 0.3031515967612216 0.1965867989729817 0.8441509019176725 1.0 0.9960624373746122 22 P50416,Q9BRT2,P00367,Q08209,Q8N5M9,P40939,Q16836,O95563 8 +Myeloid leukocyte cytokine production 0.359677785069391 0.1965687791092975 0.8441650045563656 1.0 0.9960624373746122 8 P09601,P14174 2 +Monocarboxylic acid biosynthetic process 0.2724514446514904 0.1964109588724714 0.8442885193772156 1.0 0.9960624373746122 40 Q12770,O00767,Q9P035,Q6Y1H2,Q9H7Z7,Q8NCG7,Q53GQ0,Q9H1P3,Q92604,Q9NZ01 10 +Hindbrain development 0.2739648084629419 0.1962159146078697 0.8444411721210765 1.0 0.9960624373746122 36 Q7Z4L5,P04062,O15020,O14949,P18887,O15228,Q9BRK5 7 +N acetylneuraminate catabolic process 0.4693366708385402 0.196182091896806 0.8444676442945762 1.0 0.9960624373746122 2 Q9UJ70 1 +Amino sugar catabolic process 0.4693366708385402 0.196182091896806 0.8444676442945762 1.0 0.9960624373746122 2 Q9UJ70 1 +Positive regulation of nuclease activity 0.4452097683155832 0.1957238379154228 0.8448263253008708 1.0 0.9962807179929188 4 Q05655,P26583,P23396 3 +Regulation of animal organ morphogenesis 0.3587604714601248 0.1926968635172648 0.8471963799699316 1.0 0.9978078350698908 8 Q8TAA9 1 +Development of secondary sexual characteristics 0.5117179099617669 0.1919500005074986 0.8477813708484558 1.0 0.9978078350698908 3 Q99623 1 +Regulation of monocyte chemotaxis 0.4436534115134259 0.1914254574875304 0.8481922766475627 1.0 0.9978078350698908 4 Q4KMQ2,P09429 2 +Negative regulation of dendrite morphogenesis 0.4671464330412865 0.1909139445152568 0.8485930149716332 1.0 0.9979637103641036 2 Q08209 1 +Regulation of immune effector process 0.2692326862746302 0.1907762384518195 0.8487009057237371 1.0 0.9979637103641036 44 P14174,P09601,Q99623,P55061,Q7Z434,Q96FZ2,Q08722,O15400,P11279,P15151 10 +Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 0.3577716412530332 0.1885398340327501 0.8504534923472491 1.0 0.999196231273848 8 P05141,Q969V5 2 +Columnar cuboidal epithelial cell development 0.3534208224456575 0.1867876380624131 0.8518271397316279 1.0 0.9997772453485384 9 P49841,Q00534,P04818,Q86UL3 4 +Positive regulation of fibroblast migration 0.50935407541077 0.1863944566418165 0.8521354392174265 1.0 0.9998224370223322 3 Q14155 1 +Negative regulation of protein binding 0.3014709279689193 0.1850540456143841 0.8531866452738452 1.0 1.0 22 O75381,Q9GZU8,P55061,Q14012,P16615,P49841,Q6IAN0 7 +Response to tumor necrosis factor 0.2832535572602874 0.1844107446432364 0.8536912413650464 1.0 1.0 31 P04062,Q86VX2 2 +Positive regulation of fibroblast proliferation 0.4038482692613437 0.1830621963399244 0.85474921743166 1.0 1.0 6 P11802,P14174 2 +Intra golgi vesicle mediated transport 0.3019625379579186 0.1815533187998687 0.8559332860859916 1.0 1.0 17 O95249,O14653 2 +Positive regulation of erk1 and erk2 cascade 0.3375246519775877 0.1814113393339993 0.856044719047639 1.0 1.0 12 Q99623,Q13641 2 +Phagolysosome assembly 0.5070422535211357 0.1810308698266558 0.8563433456982055 1.0 1.0 3 P61106,P51149 2 +Extrinsic apoptotic signaling pathway via death domain receptors 0.309575815110421 0.1793880482243184 0.8576330153048812 1.0 1.0 16 P09601 1 +Leukocyte proliferation 0.2722158235400304 0.178484392516515 0.8583425773647142 1.0 1.0 35 P04062,Q9HCL2 2 +Regulation of dna catabolic process 0.4618272841051161 0.1784441836200664 0.8583741525700732 1.0 1.0 2 O95831 1 +Regulation of apoptotic dna fragmentation 0.4618272841051161 0.1784441836200664 0.8583741525700732 1.0 1.0 2 O95831 1 +Positive regulation of protein k63 linked ubiquitination 0.461201501877334 0.1770075013406571 0.859502497402939 1.0 1.0 2 P61088 1 +Negative regulation of receptor mediated endocytosis 0.3785469607367321 0.1768837501192359 0.8595997028783215 1.0 1.0 7 Q13432 1 +Leukocyte differentiation 0.2676806327468483 0.1757843167441769 0.8604633912003856 1.0 1.0 61 O96005,P24390,P04062,Q8N5M9 4 +Corpus callosum development 0.4373825923606728 0.1744565912345314 0.8615066427486837 1.0 1.0 4 Q99622,P43034,Q00535 3 +Oligodendrocyte differentiation 0.3013755650632376 0.1722669597216507 0.8632276583315037 1.0 1.0 20 Q15382,Q92542,P49770,P42345,P18074,Q9NR50,P21359,Q00535,Q13144 9 +Corpus callosum morphogenesis 0.4583854818523001 0.1706218506830844 0.8645211155045385 1.0 1.0 2 Q99622 1 +Ubiquinone metabolic process 0.4210108831593054 0.1697456184273276 0.865210196316204 1.0 1.0 5 Q8NI60 1 +Innate immune response activating signal transduction 0.4351909830933032 0.1686601527219597 0.8660639632000984 1.0 1.0 4 Q16512,Q13153,O43318 3 +Response to lectin 0.4351909830933032 0.1686601527219597 0.8660639632000984 1.0 1.0 4 Q16512,Q13153,O43318 3 +Membrane invagination 0.328705438677554 0.168281287353125 0.8663619944553542 1.0 1.0 13 Q13636,Q4KMQ2,P51790 3 +Defense response to gram positive bacterium 0.5013583568307423 0.1681395351615116 0.8664735075114327 1.0 1.0 3 P04439 1 +Cerebral cortex neuron differentiation 0.4342517219787071 0.1661974821147487 0.868001540873754 1.0 1.0 4 Q96ST3,P50542,P43034 3 +Multi multicellular organism process 0.2961391569043014 0.1661841776761766 0.868012010691926 1.0 1.0 24 P41440,Q9UIQ6,P15291,P35613,Q15363,Q96QD8 6 +Regulation of dna primase activity 0.5004694835680833 0.1661618114912318 0.8680296116288133 1.0 1.0 3 Q9BRX5,Q9BRT9 2 +Short term memory 0.4561952440550546 0.1657453042513077 0.8683573914784384 1.0 1.0 2 P14672 1 +Regulation of type i interferon mediated signaling pathway 0.3281760112914104 0.1655932002567069 0.8684770988216832 1.0 1.0 13 Q969V5,Q7Z434 2 +Ribose phosphate metabolic process 0.2508431690676254 0.1642005359302439 0.8695732792225095 1.0 1.0 142 P49902,Q9HCL2,Q9BRR6,P50897,P00403,P35610,P24539,Q53GQ0,Q9NZ01,O75964,P56385,Q6Y1H2,P52789,Q8WVC6,P00846,Q8IWA4,P56134,Q8TB61,Q86UL3,P36542,P04035 21 +Regulation of lipase activity 0.3395450734061748 0.1637090148910502 0.8699602204436481 1.0 1.0 11 P50897,P16435 2 +Sulfur compound metabolic process 0.2498498517449572 0.1618802289305015 0.8714001724792135 1.0 1.0 99 O43505,Q13126,Q9Y6N5,Q9HCL2,Q11206,Q9H7Z7,Q9HC21,P50897,P35610,Q15118,Q8TB36,Q53GQ0,Q9NZ01,Q9UBX3,P15586,Q8NCH0,O60725,O75027,Q6Y1H2,Q99735,P78417,Q8TB61,Q86UL3,Q9NX62 24 +Regulation of oxidoreductase activity 0.3064163850175699 0.1608825536591368 0.8721859034631358 1.0 1.0 16 P23634,Q99623,Q15070,P16435,Q8WTV0,Q9BQ95 6 +Regulation of skeletal muscle fiber development 0.4536921151439144 0.1602688920576051 0.8726692626277404 1.0 1.0 2 Q8NEZ5 1 +Positive regulation of jun kinase activity 0.3966165413533937 0.1592862878199346 0.8734433235655155 1.0 1.0 6 Q16512,P23396,Q13153,O43318,P18031 5 +Negative regulation of lipid biosynthetic process 0.3425069521461934 0.1571544717828839 0.8751231086082283 1.0 1.0 10 Q8NF37,Q12770 2 +Terminal button organization 0.4521276595744527 0.1568986654858886 0.8753247116206753 1.0 1.0 2 Q96QK1 1 +Regulation of dendritic cell differentiation 0.4518147684605645 0.1562294751453323 0.8758521441811786 1.0 1.0 2 P09429 1 +Dendritic cell differentiation 0.4518147684605645 0.1562294751453323 0.8758521441811786 1.0 1.0 2 P09429 1 +Regulation of tolerance induction 0.4518147684605645 0.1562294751453323 0.8758521441811786 1.0 1.0 2 P09429 1 +Tolerance induction 0.4518147684605645 0.1562294751453323 0.8758521441811786 1.0 1.0 2 P09429 1 +Negative regulation of protein kinase b signaling 0.3462011327701224 0.1557991304421127 0.8761913560627197 1.0 1.0 9 Q8NFG4,O75340,Q969V5 3 +Retina development in camera type eye 0.2991210074413287 0.1535757163569906 0.877944285298393 1.0 1.0 18 Q8NF37,P20020,P23634,Q8NBN7 4 +Fucose metabolic process 0.4934161433024554 0.1508389034076121 0.8801027968682829 1.0 1.0 3 Q9BTY2 1 +Forebrain development 0.2652626374712919 0.1507911896706819 0.8801404364198353 1.0 1.0 59 Q7Z4L5,Q9NQC3,O14949,Q96N66,O94901 5 +Cell death in response to oxidative stress 0.2935120967843315 0.1477457668570632 0.8825434112366177 1.0 1.0 24 Q9UMX0,Q07820,Q99720,P04062,P23246,Q15118,Q13546,Q9NR28 8 +Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway 0.447747183979961 0.1476774633622219 0.8825973182302125 1.0 1.0 2 Q9BRG1 1 +Rna interference 0.370103415857117 0.1461617322975558 0.8837937142764924 1.0 1.0 7 Q5KU26,Q15631,O75569,Q08211,Q92879,Q9HAV4 6 +Response to reactive oxygen species 0.276246645789762 0.1453170017424714 0.8844605917582282 1.0 1.0 32 P09601,P39210,Q99720 3 +Regulation of membrane protein ectodomain proteolysis 0.4907668231611981 0.145254628595516 0.8845098358555279 1.0 1.0 3 O43847,Q9Y5X1 2 +Positive regulation of membrane protein ectodomain proteolysis 0.4907668231611981 0.145254628595516 0.8845098358555279 1.0 1.0 3 O43847,Q9Y5X1 2 +Response to type i interferon 0.295977024854639 0.1449050504638788 0.8847858388324894 1.0 1.0 17 Q7Z434,Q969V5,P23458 3 +Regulation of stem cell population maintenance 0.4115252113999533 0.1425583502646293 0.8866389930925285 1.0 1.0 5 Q9Y6J9,Q15061,A5YKK6,Q9NZN8 4 +Protoporphyrinogen ix metabolic process 0.4115232836178227 0.1425529682237259 0.88664324392671 1.0 1.0 5 P22830 1 +Intraciliary transport 0.3910474143355677 0.1415570946216214 0.8874298590884968 1.0 1.0 6 Q7Z4L5 1 +Regulation of wnt signaling pathway 0.2626520967349304 0.141341085197933 0.8876004940860347 1.0 1.0 46 Q7Z4L5,P50402,Q9H2V7,Q13641 4 +Phosphatidylinositol 3 kinase signaling 0.3343084782660921 0.139741204135574 0.8888644696036931 1.0 1.0 11 Q10713 1 +Fc epsilon receptor signaling pathway 0.4436795994993583 0.1393996666169698 0.8891343357890871 1.0 1.0 2 P19174 1 +Meiotic sister chromatid cohesion centromeric 0.4421151439298972 0.1362889739343579 0.8915928400781052 1.0 1.0 2 O60566 1 +Response to carbohydrate 0.2727507246580475 0.1361944080236065 0.8916675957290592 1.0 1.0 33 Q8N183,P62995,Q9HCL2,P49770,Q15043,Q08209,Q8N5M9,Q9NR50,O95563,Q9NWS0,Q13144 11 +Nuclear migration 0.3216638231217768 0.1330424491202839 0.8941598093348824 1.0 1.0 13 Q9UH99,O94901,Q15154,Q5SNT2 4 +Dna damage response signal transduction by p53 class mediator 0.308026575136949 0.1293144104631381 0.8971088692719904 1.0 1.0 15 O75844 1 +Midbrain development 0.2946398333792342 0.1290294870508581 0.8973343165572059 1.0 1.0 20 O14949,P24539,Q8IXJ6 3 +Phosphatidylinositol 3 phosphate biosynthetic process 0.482003129890461 0.1274549595103097 0.8985803194784523 1.0 1.0 3 O00443,Q01968 2 +Keratinocyte proliferation 0.4185973700688861 0.1270953114859395 0.8988649622625795 1.0 1.0 4 P58107,O14936,Q13247 3 +Regulation of keratinocyte proliferation 0.4185973700688861 0.1270953114859395 0.8988649622625795 1.0 1.0 4 P58107,O14936,Q13247 3 +Negative regulation of cell death 0.2468778116466815 0.1266038028419809 0.8992539869318292 1.0 1.0 214 P14174,Q07820,Q9BVC6,Q9HCL2,Q15392,P45880,Q15041,P50897,P09601,O60313,Q9Y241,P12235,Q9P0J0,O15118,P21796,Q9H4A6,Q9H3K2,Q9H300,Q8N2F6,Q8IWB1,Q4ZIN3,Q99623,Q86XL3,Q86UE4,Q9NVI7,P31751,P04062,P51812,P55061,P05141,Q12981,P16435,Q01105 33 +Epithelial cell proliferation 0.2634335521538314 0.1264138581571727 0.8994043329312988 1.0 1.0 43 P09601,P57105,Q9NQC3,Q8WTV0 4 +Negative regulation of wound healing 0.3853383458646729 0.1239253139088342 0.9013744098381836 1.0 1.0 6 O14936,Q05655,P58107,P55011,O75122 5 +Regulation of macrophage activation 0.3853206165561989 0.1238714322929176 0.9014170724350998 1.0 1.0 6 P14174 1 +Lymphoid progenitor cell differentiation 0.4801251956181627 0.1237758617678754 0.901492744340158 1.0 1.0 3 O43809,Q8NFG4 2 +Pro b cell differentiation 0.4801251956181627 0.1237758617678754 0.901492744340158 1.0 1.0 3 O43809,Q8NFG4 2 +Positive regulation of ion transport 0.2657585513312038 0.1236915829093344 0.9015594763453124 1.0 1.0 37 O00483,P14174,Q13586,Q9P246,P08183,P78417,O76024,O75323,Q15042,P54709,P20020,Q4KMQ2,Q15041,Q00535 14 +Response to topologically incorrect protein 0.262505716026955 0.1220630909296777 0.9028490524189712 1.0 1.0 58 O14657,Q96HE7,Q15629,P57088,Q96CS3,P48723,P55061,Q92905,Q9GZP9,Q9UKV5,Q7Z2K6,Q15363,Q9Y4P3,Q8TCJ2,Q6NTF9,P46379 16 +Spindle assembly involved in female meiosis 0.4788732394366266 0.1213497277963517 0.9034140339236854 1.0 1.0 3 O14965,O95067 2 +Primary alcohol metabolic process 0.2994378503119077 0.1209166847559584 0.903757026614148 1.0 1.0 16 Q9Y394,P51648,Q9HBH5,Q8NBN7 4 +Regulation of chromatin binding 0.384089054792852 0.1201419476858447 0.9043707035779398 1.0 1.0 6 Q7L2J0,Q7Z5K2 2 +Sterol homeostasis 0.3240152879762003 0.1169501985789234 0.9068995183388772 1.0 1.0 12 O15118,Q8WTV0 2 +Regulation of atp biosynthetic process 0.3615014464566324 0.1161930242933612 0.907499565114982 1.0 1.0 7 Q8NFG4,P00403 2 +Regulation of synaptic transmission gabaergic 0.4760563380281767 0.1159688398875542 0.9076772373021544 1.0 1.0 3 P33176,P21359 2 +Ventricular cardiac muscle cell differentiation 0.4311639549436709 0.1156496680744895 0.90793019753862 1.0 1.0 2 P06493 1 +Ventricular cardiac muscle cell development 0.4311639549436709 0.1156496680744895 0.90793019753862 1.0 1.0 2 P06493 1 +Membrane protein proteolysis 0.3236638850383594 0.1153281136984066 0.9081850555222236 1.0 1.0 12 Q9H300,Q9Y4W6,Q9NZ08 3 +Gmp salvage 0.4132748904195369 0.1146540337371673 0.9087193493334204 1.0 1.0 4 P55263,P00492,P00813 3 +Memory 0.3610342685672096 0.1146053410142651 0.908757946090386 1.0 1.0 7 O00264 1 +Exocytosis 0.2603477327391166 0.1131674079704 0.909897834310882 1.0 1.0 75 P49755,P61026,O43760,Q5JRA6,P09601,P49841,Q92543,Q92905,Q4J6C6,Q6IQ22,Q8N5M9,Q9Y3C0,Q13636,Q9BRK5,O15498,P11279,Q7L0J3,P16615 18 +Synapse maturation 0.4115522070921289 0.1107218669280493 0.9118369052946242 1.0 1.0 4 P07196 1 +Negative regulation of necrotic cell death 0.3989711596341648 0.1087816205450559 0.913375701977621 1.0 1.0 5 Q13546,P12235 2 +Negative regulation of programmed necrotic cell death 0.3989711596341648 0.1087816205450559 0.913375701977621 1.0 1.0 5 Q13546,P12235 2 +Folic acid containing compound metabolic process 0.3104000307638697 0.1074864635717882 0.914403063611509 1.0 1.0 14 Q9H2D1 1 +Negative regulation of endocytosis 0.3341959099951114 0.1065788667578998 0.9151230849584788 1.0 1.0 9 Q13432 1 +Chaperone mediated autophagy 0.3372393880698953 0.1064234171707174 0.9152464143653904 1.0 1.0 8 P10619 1 +Negative regulation of fat cell differentiation 0.3368803159297898 0.1050631214047049 0.9163257221578364 1.0 1.0 8 Q8N4Q0,Q8IXJ6 2 +Calcium mediated signaling using intracellular calcium source 0.4068539968155864 0.1002348610719944 0.9201578702355556 1.0 1.0 4 P51572 1 +T cell mediated immunity 0.3025660759452264 0.1002255206160767 0.9201652855002068 1.0 1.0 15 Q14699,O15400,P53634,P04439,P15151 5 +Positive chemotaxis 0.4067783251314558 0.1000688021594434 0.9202897032489656 1.0 1.0 4 P14174,P26583 2 +Cellular response to estradiol stimulus 0.4673663336546256 0.1000502311535278 0.9203044467774052 1.0 1.0 3 O95831 1 +Regulation of heart contraction 0.2776577506977277 0.0983752042396593 0.9216343633103156 1.0 1.0 29 P23634,P78417,O75844,P05023,P17302,Q6PI78,P20020,P16615 8 +Hyperosmotic response 0.331500127989891 0.0959484386781197 0.9235615235107462 1.0 1.0 9 Q9BPX6 1 +Regulation of cell cell adhesion 0.2580344479285694 0.0950759786328902 0.9242544779026822 1.0 1.0 46 Q11206,Q9HCL2,Q08722,P30825 4 +Detection of abiotic stimulus 0.3338141445439661 0.0935600810449281 0.9254586211763942 1.0 1.0 8 Q13432 1 +Sertoli cell development 0.4635367762128424 0.0933620682233621 0.9256159240288068 1.0 1.0 3 Q9Y2H6,P51659 2 +Cellular response to extracellular stimulus 0.2604260887271372 0.0920759802306092 0.926637672367359 1.0 1.0 42 P09601,Q9Y371,P04062,P21964 4 +Reticulophagy 0.35420760491207 0.0918899039771526 0.926785512982631 1.0 1.0 7 Q86VR2,Q9Y6I9 2 +Type b pancreatic cell apoptotic process 0.4625978090766923 0.0917527211574989 0.9268945085871744 1.0 1.0 3 O76024,Q13247 2 +Cellular hyperosmotic response 0.3538804441626623 0.090824404726915 0.927632118024488 1.0 1.0 7 Q9BPX6 1 +Thymocyte apoptotic process 0.4619718309859255 0.090686496416915 0.9277417007134604 1.0 1.0 3 P04637,P00813 2 +Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.4613944690606391 0.0897078105830113 0.9285194090230318 1.0 1.0 3 Q07820 1 +Regulation of synaptic transmission glutamatergic 0.4017875648518965 0.089317279570381 0.9288297618423268 1.0 1.0 4 Q8NBU5,Q00535 2 +Glutamate biosynthetic process 0.4611370513154659 0.0892729249379193 0.9288650109070165 1.0 1.0 3 P00367 1 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.3525618943016766 0.0865519079390466 0.9310276942775052 1.0 1.0 7 P55061 1 +G quadruplex dna unwinding 0.4000239273013998 0.0856126702560837 0.9317743260346742 1.0 1.0 4 P51530 1 +Hydrogen peroxide metabolic process 0.3288327463164995 0.0855894639483467 0.9317927742752266 1.0 1.0 9 P00403 1 +Response to antibiotic 0.3286726595526006 0.0849728703685507 0.9322829589934454 1.0 1.0 9 P50416,P23458 2 +Regulation of response to tumor cell 0.3994523155501618 0.0844226225035968 0.9327204213329524 1.0 1.0 4 P15151 1 +Response to virus 0.2560933969289407 0.0825218183953271 0.9342317689335976 1.0 1.0 80 Q9HCL2,O75844,O43657,O60858 4 +Regulation of protein localization to cell periphery 0.268494566917716 0.0818188833575597 0.9347907396711894 1.0 1.0 32 P23634,Q9BXS4,O15400,Q9UNK0,O00264,O15258,P98194,Q9HD26 8 +Neuron projection extension 0.2612363533417142 0.0816752490416052 0.9349049609891766 1.0 1.0 35 Q9NQC3,Q969V5 2 +Icosanoid transport 0.4563322043993831 0.0813209501049585 0.9351867133924328 1.0 1.0 3 P14174 1 +Regulation of synapse structure or activity 0.2635062684734933 0.0791638984083095 0.9369022593377976 1.0 1.0 34 P50897,O00264 2 +Heart morphogenesis 0.2807465434986105 0.0790885540802859 0.9369621875159522 1.0 1.0 26 Q9NQC3 1 +Positive regulation of syncytium formation by plasma membrane fusion 0.3696147751219235 0.0783364567143191 0.9375604182881948 1.0 1.0 6 P41440 1 +Regulation of syncytium formation by plasma membrane fusion 0.3696147751219235 0.0783364567143191 0.9375604182881948 1.0 1.0 6 P41440 1 +Positive regulation of cell activation 0.2598410726845588 0.0782657673696125 0.9376166475877392 1.0 1.0 40 P14174,Q9HCL2,Q96FZ2,Q08722,P04439,P11279,P30825 7 +Cellular response to fatty acid 0.3692685333643759 0.077383206300612 0.9383187001499278 1.0 1.0 6 P11802 1 +T cell proliferation 0.284194981591041 0.0772478239897179 0.9384263972341635 1.0 1.0 23 Q9HCL2 1 +Action potential 0.2850859730168867 0.0768468790672686 0.93874535686985 1.0 1.0 22 P04062,P16615 2 +Galactose catabolic process 0.45320813771519 0.0763187445147244 0.9391655133685712 1.0 1.0 3 P16278,P51570 2 +Embryonic brain development 0.3855308487316194 0.0755257668421898 0.9397963971048222 1.0 1.0 5 P27635,P62995,P35222,O60508 4 +Regulation of meiotic nuclear division 0.3948285540689824 0.0749884605926292 0.940223893154535 1.0 1.0 4 Q8IXJ6 1 +Quinone metabolic process 0.3229047850511093 0.0747989037176635 0.9403747140824604 1.0 1.0 10 Q8NI60,Q8N0U8 2 +Response to isoquinoline alkaloid 0.4507042253521218 0.0724048250368724 0.9422797450512616 1.0 1.0 3 P06744,P63151 2 +Response to salt stress 0.3480283583889493 0.0721308601620021 0.9424977673244096 1.0 1.0 7 Q9BPX6 1 +Interleukin 6 mediated signaling pathway 0.3925836584067774 0.0705316154333866 0.9437705377241729 1.0 1.0 4 P23458 1 +Regulation of vasculature development 0.2589363678209866 0.0700458924476013 0.9441571324237814 1.0 1.0 40 P09601,P57105,P52789,Q86UE4 4 +Regulation of endocytosis 0.2561925163439145 0.0695399316946147 0.944559848671688 1.0 1.0 45 P41440,P50897,Q8NBU5,Q13432,P57105,Q96PU5,Q4KMQ2 7 +Embryonic axis specification 0.3465260371128877 0.0674450809085208 0.9462273814915154 1.0 1.0 7 Q15363,Q8N2A8 2 +Embryonic pattern specification 0.3465260371128877 0.0674450809085208 0.9462273814915154 1.0 1.0 7 Q15363,Q8N2A8 2 +Actin filament based movement 0.2790465062771893 0.0673120382296772 0.9463332935043464 1.0 1.0 26 Q9UM22,P16615 2 +Synapse assembly 0.2825569043083612 0.0664555128787179 0.9470151749523672 1.0 1.0 17 O15020,O14966,O15228,Q13641 4 +Trna pseudouridine synthesis 0.39768460575718 0.0646329378703169 0.9484662589006988 1.0 1.0 2 Q96PZ0 1 +Regulation of proton transport 0.3257148322594192 0.0641715006009423 0.9488336698346264 1.0 1.0 8 Q8TAD4 1 +Positive regulation of deoxyribonuclease activity 0.4450704225352198 0.0639070781327364 0.9490442162673096 1.0 1.0 3 Q05655,P23396 2 +Positive regulation of i kappab phosphorylation 0.396120150187717 0.0626779893350767 0.950022924890414 1.0 1.0 2 Q96HY6 1 +Regulation of i kappab phosphorylation 0.396120150187717 0.0626779893350767 0.950022924890414 1.0 1.0 2 Q96HY6 1 +Pigment granule maturation 0.4425665101721531 0.0602666928111474 0.9519432289948536 1.0 1.0 3 O14617,Q9BXS5 2 +Pigment accumulation 0.4425665101721531 0.0602666928111474 0.9519432289948536 1.0 1.0 3 O14617,Q9BXS5 2 +Transcription coupled nucleotide excision repair 0.3866624921728189 0.0591644891114438 0.9528210936576142 1.0 1.0 4 P19447,P18074,Q93009 3 +Cellular response to antibiotic 0.4410015649452372 0.0580338280405343 0.9537216830439844 1.0 1.0 3 P04637,P61160 2 +Response to actinomycin d 0.4410015649452362 0.0580338280405332 0.9537216830439852 1.0 1.0 3 P04637,O95251 2 +Negative regulation of b cell apoptotic process 0.4403068957998461 0.0570530868946482 0.9545029067465828 1.0 1.0 3 P14174 1 +Regulation of b cell apoptotic process 0.4403068957998461 0.0570530868946482 0.9545029067465828 1.0 1.0 3 P14174 1 +Adiponectin activated signaling pathway 0.3914267834793376 0.057031973309692 0.9545197255648136 1.0 1.0 2 P33121 1 +Regulation of wound healing spreading of epidermal cells 0.3850970569818352 0.0562534325941036 0.9551399154603316 1.0 1.0 4 P42345,Q96AC1,O75122 3 +Wound healing spreading of epidermal cells 0.3850970569818352 0.0562534325941036 0.9551399154603316 1.0 1.0 4 P42345,Q96AC1,O75122 3 +Astrocyte differentiation 0.3148425151271103 0.0560577678818365 0.9552957873520193 1.0 1.0 11 Q7Z4L5,P08670 2 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.3847839699436397 0.0556759472771033 0.955599961065946 1.0 1.0 4 Q709C8,Q16543,O95140 3 +Regulation of ribosome biogenesis 0.3898623279098776 0.0552220144254829 0.9559615907178995 1.0 1.0 2 Q5T3I0 1 +Mitochondrial fragmentation involved in apoptotic process 0.3764484810523074 0.0548085952861002 0.956290952649462 1.0 1.0 5 Q96QK1,Q9NT62,O00429,Q9Y3D6 4 +Response to vitamin 0.3219241792365463 0.0509300511447717 0.9593812592255722 1.0 1.0 8 P20020,Q8TB36 2 +Proteolysis 0.2349701221502177 0.0507743802223695 0.9595053061578152 1.0 1.0 377 P67812,Q96A26,O60858,P46379,Q6P179,Q9H8M7,Q9UHG3,Q70CQ2,O75844,Q4J6C6,P36551,Q9NZ08,Q9Y4W6,Q4ZIN3,Q969V5,Q9UG56,Q9NZJ7,Q8TAD4,P49841,Q96HE7,O14773,P04062,Q10713,Q92905,P28072,P42785,P53634,Q6NTF9,Q00535,Q15005,Q92896,Q9UJX5,Q8NBM8,Q9Y679,Q9BXS4,P55786,Q9HB40,Q12797,Q96A33,Q9P0J0,Q9H300,Q9BXK5,Q96KC8,Q96PU5,P42892,P10619,Q9UBV2,Q9NWW5,P09960,Q9UNS2,Q8NBM4,O43292,Q15392,P49721,Q15041,O75503,P51572,O75340,P28074,Q8TCJ2,P49755,Q7L5N1,Q9GZP9,Q8IXJ6,Q9UMX0,Q9NQH7,P16435,Q9UIQ6,Q969V3,Q9UBU6,Q96CS3,P51784,Q7Z2K6,Q9GZU8,Q9UKV5,Q96FZ2,Q92643,O00487,P51812,P27824,A4D1P6,P43686,Q9NR28 83 +Positive regulation of behavior 0.4356807511737194 0.0506843248553096 0.9595770675475612 1.0 1.0 3 Q96QK1,Q92769 2 +Germ cell migration 0.4353677621283356 0.0502635958473891 0.9599123333875852 1.0 1.0 3 P05556,P78310 2 +Natural killer cell activation 0.3212624785044008 0.0486529974279861 0.9611958341007754 1.0 1.0 8 P11279 1 +Regulation of leukocyte proliferation 0.2812653917062866 0.0472416506737887 0.9623206321243736 1.0 1.0 20 Q9HCL2 1 +Regulation of lipid localization 0.2802267430724587 0.0464190637191214 0.9629762422391716 1.0 1.0 22 Q9BZF1,P31751,P14174,Q9Y3D6,Q9BXB4,Q9Y6B6,Q8WTV0,O15260 8 +Defense response to bacterium 0.3030926878745156 0.0459492592754998 0.9633506923881336 1.0 1.0 13 P61106,P62820,Q7Z434,Q8IXJ6,P26583,P04439 6 +Axoneme assembly 0.4320631821910671 0.0458995069092117 0.9633903471940344 1.0 1.0 3 A0AVF1 1 +Positive regulation of interleukin 8 production 0.3391757916659805 0.0452012027022354 0.963946935614096 1.0 1.0 7 P62820,Q13546,Q7Z434 3 +Regulation of protein complex stability 0.3719373634974517 0.0450537987486987 0.9640644272564332 1.0 1.0 5 Q969V3 1 +Positive regulation of transmembrane transport 0.2617065976487353 0.0450532645625206 0.9640648530429828 1.0 1.0 33 Q9BZF1,O00483,P31751,Q13586,P08183,P78417,O75323,Q4KMQ2,Q15041,Q00535 10 +Intrinsic apoptotic signaling pathway in response to dna damage 0.2789480441215059 0.0436276886241697 0.9652011803750772 1.0 1.0 23 P14174,Q07820,Q9BVC6,P09601,P46379 5 +Endocytosis 0.239370852592279 0.0432982795541813 0.9654637626548288 1.0 1.0 106 P50897,P41440,Q8NBU5,P51790,Q5VW38,P62820,Q9NX40,Q13432,Q9UBG0,O15118,P57105,Q96PU5,Q14108,O15260,Q4KMQ2,Q8WTV0 16 +Response to acid chemical 0.2802272125550816 0.0411425661043094 0.9671822404703444 1.0 1.0 20 Q14103,Q9UQB8,P23634,Q9P2J5,P55061,Q15388,O95831,Q99729,O94826 9 +Positive regulation of inflammatory response 0.3017949826612872 0.0402095865303057 0.9679260348664692 1.0 1.0 13 P53634,Q99735,Q08722,Q13546 4 +Secretion by tissue 0.4273070516292403 0.0398667600602311 0.9681993516538544 1.0 1.0 3 P17302 1 +Regulation of skeletal muscle cell differentiation 0.3757044458359362 0.0396131498351566 0.9684015436160645 1.0 1.0 4 P17844,Q9BYT8,Q9BRT2 3 +Dsrna processing 0.2799323917264321 0.0394175435461145 0.96855749305169 1.0 1.0 20 Q15631,O75844,O75569,P22626,Q13546 5 +Lateral ventricle development 0.3745306633291536 0.0393188948059464 0.9686361423871608 1.0 1.0 2 Q00534 1 +Forebrain morphogenesis 0.3745306633291491 0.0393188948059422 0.968636142387164 1.0 1.0 2 P21359 1 +Tissue migration 0.2520939151768646 0.0371831033163961 0.9703390108959484 1.0 1.0 51 P09601,P57105,Q9NQC3,Q8WTV0 4 +Sperm motility 0.3741772623792076 0.0370410264088867 0.9704522938273394 1.0 1.0 4 P23634 1 +Receptor localization to synapse 0.3057550210681701 0.0367306908889643 0.9706997373573952 1.0 1.0 12 P57105 1 +Positive regulation of nucleobase containing compound transport 0.4247261345853002 0.0367144205956452 0.970712710422896 1.0 1.0 3 Q07666,Q16630 2 +Positive regulation of rna export from nucleus 0.4247261345853002 0.0367144205956452 0.970712710422896 1.0 1.0 3 Q07666,Q16630 2 +Negative regulation of tor signaling 0.373724508995691 0.0362856371436457 0.9710546022976017 1.0 1.0 4 O75340 1 +Smooth muscle tissue development 0.371088861076333 0.036187998981098 0.9711324551486682 1.0 1.0 2 P21359 1 +Monocarboxylic acid transport 0.3533856246980179 0.0360916320731176 0.9712092946208104 1.0 1.0 6 P14174,O95563 2 +Response to thyroxine 0.3704630788485509 0.0356353126785065 0.9715731507483436 1.0 1.0 2 O94826 1 +Response to l phenylalanine derivative 0.3704630788485509 0.0356353126785065 0.9715731507483436 1.0 1.0 2 O94826 1 +Gamma aminobutyric acid metabolic process 0.3701501877346603 0.0353608610674368 0.9717919935239294 1.0 1.0 2 O43175 1 +Regulation of long chain fatty acid import into cell 0.4235584552362942 0.0353160020363741 0.9718277635103852 1.0 1.0 3 P31751 1 +Programmed necrotic cell death 0.2896711024170696 0.0349017573808544 0.97215807928118 1.0 1.0 15 Q13510 1 +Regulation of actin nucleation 0.3356314634910692 0.0348867186444958 0.9721700711538126 1.0 1.0 7 Q9Y2A7,P60983,Q7L576,P53365,P53367,Q9Y6W5 6 +Regulation of arp2 3 complex mediated actin nucleation 0.3356314634910692 0.0348867186444958 0.9721700711538126 1.0 1.0 7 Q9Y2A7,P60983,Q7L576,P53365,P53367,Q9Y6W5 6 +Carnitine metabolic process 0.352616029259028 0.0342139289830521 0.9727065593220184 1.0 1.0 6 P16435,P23786 2 +Positive regulation of actin cytoskeleton reorganization 0.4224891186584997 0.0340504613365345 0.972836911680413 1.0 1.0 3 Q00535 1 +Hair follicle maturation 0.3664625711735257 0.0336957895550124 0.9731197365160092 1.0 1.0 5 Q08J23,P18074 2 +Negative regulation of reactive oxygen species metabolic process 0.3091006903830083 0.0331535328016767 0.9735521531850384 1.0 1.0 11 P52789,Q8IXJ6 2 +Trna wobble uridine modification 0.3658926671539761 0.0325438246296773 0.9740383675224564 1.0 1.0 5 Q969Y2,O75648 2 +Trna wobble base modification 0.3658926671539761 0.0325438246296773 0.9740383675224564 1.0 1.0 5 Q969Y2,O75648 2 +Middle ear morphogenesis 0.3713212273011886 0.0323305676865587 0.9742084324522418 1.0 1.0 4 P63173,P54802,O75569 3 +Positive regulation of long term synaptic potentiation 0.3648310387984866 0.0308851315838025 0.9753611475445628 1.0 1.0 2 Q13501 1 +Cell fate specification 0.4194053208137792 0.0304811790260526 0.9756833033680312 1.0 1.0 3 P05556,P35222 2 +Pyrimidine deoxyribonucleoside metabolic process 0.3635794743429204 0.0298832451991848 0.9761601682764544 1.0 1.0 2 P04183 1 +Small rna loading onto risc 0.3697557921101984 0.0298037011273603 0.976223607006649 1.0 1.0 4 Q08211,Q5KU26,O75569 3 +Cell junction disassembly 0.4181620395211094 0.0290756843661703 0.9768042286619756 1.0 1.0 3 Q00535 1 +Smoothened signaling pathway 0.278121612190338 0.0288912001789789 0.9769513639337076 1.0 1.0 20 Q7Z4L5,P16435,Q96J42 3 +Pyrimidine deoxyribonucleotide biosynthetic process 0.3639210773567223 0.0286027922995155 0.9771813850639528 1.0 1.0 5 P34896,P32321,P33316,P04818 4 +Regulation of axonogenesis 0.2745839633383316 0.0283359217126972 0.9773942307106414 1.0 1.0 25 Q8N0X7,P07196,Q9NQC3,P49841 4 +Intrinsic apoptotic signaling pathway in response to osmotic stress 0.3595118898623195 0.0267580891708223 0.9786526812345202 1.0 1.0 2 P16989 1 +Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress 0.3595118898623195 0.0267580891708223 0.9786526812345202 1.0 1.0 2 P16989 1 +Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress 0.3595118898623195 0.0267580891708223 0.9786526812345202 1.0 1.0 2 P16989 1 +Positive regulation of t cell mediated immunity 0.3102348710557152 0.0263602486944197 0.9789700000697938 1.0 1.0 10 O15400,P15151 2 +Replicative senescence 0.3570087609511738 0.0249323112370221 0.9801089545992784 1.0 1.0 2 P04637 1 +Dtmp metabolic process 0.3659987476518416 0.0238974549318523 0.9809344043745942 1.0 1.0 4 P34896,P33316,P04818 3 +Pyrimidine deoxyribonucleoside monophosphate metabolic process 0.3659987476518416 0.0238974549318523 0.9809344043745942 1.0 1.0 4 P34896,P33316,P04818 3 +Pyrimidine deoxyribonucleoside monophosphate biosynthetic process 0.3659987476518416 0.0238974549318523 0.9809344043745942 1.0 1.0 4 P34896,P33316,P04818 3 +Positive regulation of smooth muscle cell migration 0.3538798498122567 0.0227515136610456 0.9818484844941158 1.0 1.0 2 Q96N67 1 +Mitochondrial acetyl coa biosynthetic process from pyruvate 0.3647463994990549 0.021978152145178 0.9824653833908632 1.0 1.0 4 P09622,O95563,P08559 3 +Gtp biosynthetic process 0.3641202254226643 0.0210277374403114 0.9832235292869722 1.0 1.0 4 P15531,P20839,P12268 3 +Sensory system development 0.2539630809551593 0.0206213217984512 0.983547731746042 1.0 1.0 37 P23634,Q8NBN7,O43819,Q8NF37,P17302,P08670,P20020 7 +Second messenger mediated signaling 0.2688105444121904 0.0193701421806457 0.9845458290265764 1.0 1.0 28 P23634,Q9Y3D6,P78417,P51572,O75844,P42345,Q08209,P49841,P16615 9 +Positive regulation of programmed necrotic cell death 0.4087636932707464 0.019062668498308 0.9847911122375256 1.0 1.0 3 P04637,Q13546 2 +Regulation of calcineurin mediated signaling 0.3460034935745129 0.0185570866559433 0.985194436822727 1.0 1.0 6 P23634,P49841 2 +Fat cell proliferation 0.3429286608260191 0.0159613750181526 0.9872652060371364 1.0 1.0 2 Q13501 1 +Regulation of histone h2b ubiquitination 0.402503912363078 0.0129776968186377 0.9896455867238858 1.0 1.0 3 P50750,O75150 2 +Cytokine production involved in immune response 0.2952501836469627 0.0120067528423163 0.9904202274556696 1.0 1.0 13 P09601,P14174,Q7Z434 3 +Negative regulation of actin nucleation 0.335106382978714 0.0118563556419862 0.9905402185183008 1.0 1.0 2 P60983 1 +Negative regulation of arp2 3 complex mediated actin nucleation 0.335106382978714 0.0118563556419862 0.9905402185183008 1.0 1.0 2 P60983 1 +Negative regulation of cold induced thermogenesis 0.3100529097776422 0.0116758764566524 0.9906842101060798 1.0 1.0 8 Q8NFG4,Q9UIQ6,Q96N67 3 +Positive regulation of developmental growth 0.2706972359573753 0.0111003868993784 0.991143354558314 1.0 1.0 26 Q9HCL2,Q969V5 2 +Ornithine metabolic process 0.3326032540675749 0.0106639509361268 0.9914915594543072 1.0 1.0 2 P54886 1 +Positive regulation of interleukin 1 production 0.3080399393923284 0.0106161971994749 0.9915296592667756 1.0 1.0 9 Q96RD7 1 +Positive regulation of histone phosphorylation 0.33197747183979 0.0103746428899488 0.9917223811056556 1.0 1.0 2 P50750 1 +Meiosis i cell cycle process 0.2744235371127547 0.0102110163358375 0.9918529292912992 1.0 1.0 18 O94901,Q9BTX1 2 +Regulation of focal adhesion disassembly 0.331038798498113 0.009947167455177 0.9920634395460136 1.0 1.0 2 Q15555 1 +Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity 0.3310387984981126 0.0099471674551767 0.9920634395460136 1.0 1.0 2 P18031 1 +Negative regulation of blood pressure 0.3556501239240048 0.0087718867637695 0.9930011367379448 1.0 1.0 4 P42785 1 +Cellular response to leucine starvation 0.3551080203688297 0.0080252285551687 0.9935968627705783 1.0 1.0 4 Q9P2J5,P42345 2 +Myeloid leukocyte differentiation 0.2661500255631971 0.0010333194266177 0.9991755305298452 1.0 1.0 28 P04062,Q8N5M9 2 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..331517eaa7cf0f7bb0c0089dffbc000e6936742c --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Acrosome reaction", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of janus kinase activity", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activation of store operated calcium channel activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult heart development", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B 1 b cell differentiation", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac myofibril assembly", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac right ventricle morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cholesterol", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide 1 phosphate transport", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Choline transport", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion import", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Corticotropin secretion", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil mediated immunity", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain dorsal ventral pattern formation", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactolipid biosynthetic process", "Galactolipid metabolic process", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid catabolic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 mediated signaling pathway", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal epithelial structure maintenance", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lacrimal gland development", "Lactate metabolic process", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymph vessel development", "Lymph vessel morphogenesis", "Lymphangiogenesis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane fusion involved in viral entry into host cell", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic process involved in development", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of behavior", "Negative regulation of binding", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell proliferation involved in kidney development", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of feeding behavior", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of gonadotropin secretion", "Negative regulation of granulocyte chemotaxis", "Negative regulation of granulocyte differentiation", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of hexokinase activity", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 beta production", "Negative regulation of interleukin 1 production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Olfactory nerve development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Otic vesicle development", "Otic vesicle formation", "Otic vesicle morphogenesis", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericardium development", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet dense granule organization", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial cell proliferation involved in wound healing", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix constituent secretion", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of leukocyte tethering or rolling", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of store operated calcium channel activity", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper 17 cell differentiation", "Positive regulation of t helper 17 type immune response", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic development", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Proline transport", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein de adp ribosylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to non motile cilium", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein sialylation", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of acrosome reaction", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane depolarization", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell proliferation involved in kidney development", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of corticotropin secretion", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of eating behavior", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endosome to plasma membrane protein transport", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix constituent secretion", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of gonadotropin secretion", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of growth rate", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of leukocyte tethering or rolling", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphangiogenesis", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of mesodermal cell differentiation", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of cardiac muscle", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of store operated calcium entry", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 17 cell differentiation", "Regulation of t helper 17 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of voltage gated sodium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoprotein", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to herbicide", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to inactivity", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 2", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle inactivity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to stimulus involved in regulation of muscle adaptation", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Semicircular canal development", "Semicircular canal morphogenesis", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of bitter taste", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of sweet taste", "Sensory perception of taste", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Sialylation", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Store operated calcium entry", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell antigen processing and presentation", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone mediated signaling pathway", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent glycoprotein erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Ureter development", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG5", "ALKBH5", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP8", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCCIP", "BCKDHB", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BEND3", "BET1", "BIRC6", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf57", "C12orf73", "C19orf70", "C1QBP", "C2CD5", "C2orf49", "C9orf64", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPI", "CENPK", "CENPU", "CENPV", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG3", "COG8", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHPS", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM129B", "FAM162A", "FAM192A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO21", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGCX", "GGH", "GHITM", "GIGYF2", "GINS3", "GINS4", "GIPC1", "GJA1", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH1", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JAK1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "MACF1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MALT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED14", "MED16", "MED18", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METTL1", "METTL3", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGAT2", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL20", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS27", "MRPS28", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFMT", "MTFP1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NEMF", "NENF", "NF1", "NFATC2IP", "NFRKB", "NFS1", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMK", "PON2", "POP1", "POR", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB29", "RAB2A", "RAB31", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP7", "RBFA", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM47", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REEP6", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF2", "RNF25", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARAF", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP3", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDAD1", "SDE2", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A4", "SLC30A5", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP47", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX19", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSRP1", "ST3GAL4", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STEAP3", "STIM1", "STIM2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TAF15", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TEAD1", "TECR", "TEFM", "TELO2", "TERF2IP", "TES", "TEX2", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM10B", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TM9SF3", "TM9SF4", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM14C", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TP53", "TP53I11", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRIM13", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIO", "TRIP10", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPAN10", "TSPAN6", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUBGCP5", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFM1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS13C", "VPS13D", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WBP11", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF131", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF830", "ZPR1", "ZRANB2", "ZW10", "ZYG11B", "ZYX", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABHD12", "ACAD11", "ACADVL", "ACBD5", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL1", "ACTR2", "ACTR3", "ADA", "ADK", "ADPGK", "AFG3L2", "AGK", "AGPAT1", "AIFM1", "AIP", "AKAP8", "AKT2", "ALDH18A1", "ALDH3A2", "ALG1", "ALG11", "ALG12", "AMFR", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANKLE2", "ANKRD13A", "ANO6", "AP1M1", "AP3D1", "APOO", "APOOL", "ARCN1", "ARFIP1", "ARFIP2", "ARHGEF7", "ARL6IP1", "ARL6IP5", "ARL8B", "ARMC10", "ASAH1", "ASNA1", "ASPH", "ATAD1", "ATAD3A", "ATAD3B", "ATG3", "ATG9A", "ATL2", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATPAF1", "AUP1", "AURKA", "B4GALT1", "B4GAT1", "BAG6", "BAIAP2", "BCAP31", "BCCIP", "BCL2L13", "BCS1L", "BNIP1", "BSG", "BUB1B", "C12orf57", "C12orf73", "C19orf70", "C1QBP", "CAMK1", "CANT1", "CANX", "CARM1", "CASK", "CASP2", "CCDC47", "CCNB2", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDIPT", "CDK1", "CDK4", "CDK5", "CDK6", "CDK9", "CDS2", "CELF1", "CEPT1", "CERS1", "CERS2", "CETN2", "CHCHD3", "CHKA", "CHST14", "CIRBP", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLN5", "CLN6", "CLPTM1", "CLPTM1L", "CLUH", "CMAS", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT9", "COA3", "COG3", "COLEC12", "COMMD7", "COMT", "COPS3", "COPS5", "COPS6", "COQ8A", "COQ9", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRTAP", "CTCF", "CTNNB1", "CTSA", "CTSC", "CUL4A", "CXADR", "CYB5B", "CYB5R1", "CYFIP1", "CYP51A1", "DAGLB", "DCAKD", "DCTD", "DCTN1", 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"GOSR1", "GOSR2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPHN", "GPI", "GPR107", "GPR108", "GPX8", "GSK3B", "GSTO1", "GTF2H1", "GTPBP3", "GUSB", "GYS1", "HACD2", "HACD3", "HADH", "HADHA", "HCCS", "HDAC1", "HDAC2", "HEATR3", "HGS", "HIGD1A", "HK2", "HLA-A", "HLA-C", "HMCES", "HMGB1", "HMGB2", "HMGCR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPD", "HNRNPK", "HPRT1", "HPS6", "HS2ST1", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSPA13", "ICMT", "IER3IP1", "IGF2BP1", "IGF2BP2", "IKBIP", "ILVBL", "IMMT", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "ING5", "IPO4", "ITGB1", "ITM2B", "ITM2C", "ITPRIP", "JAGN1", "JAK1", "KAT7", "KDELR1", "KDELR3", "KDSR", "KHDRBS1", "KHSRP", "KIDINS220", "KIF11", "KIF1A", "KIF3A", "KIF5B", "KLC1", "LAMP1", "LAMP2", "LARP4B", "LARS", "LBR", "LCLAT1", "LDAH", "LEMD2", "LETM1", "LGALS3BP", "LLGL1", "LMAN1", "LMF2", "LNPEP", "LNPK", "LPCAT1", "LPGAT1", "LRRC8A", "LRRC8C", "LSS", "LTA4H", "LYSMD3", "MAGT1", "MAIP1", "MAN2A1", "MAP3K7", 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0.016557063421344 5.800297163257445e-06 +Respirasome 25 49 3.565611619176036 0.0003630086204349 15.08495145631068 43.37378640776699 1.2524823540042158 0.2922262294299136 6.290312072426717 4.489587979561489 1.7783434517583476 0.3462844006183536 3.180745356375291e-10 5.111567422339664e-05 0.0001514529355526 1.426109138097113e-09 3.6104841492554654e-10 +Mitochondrial protein containing complex 58 164 3.5135249084324744 0.0004422029514037 45.62621359223301 153.59708737864077 0.8032126729603613 0.4024101172023991 21.080430630469312 12.423857071229754 2.191669513941161 0.4117346592056412 1.4705920125867595e-14 1.877004006009265e-09 1.9021839792444686e-09 1.5321742049740318e-11 3.302129237065147e-17 +Lysosomal lumen 16 31 3.427780745859928 0.0006085367226296 18.075242718446603 34.54368932038835 0.7848519845050315 0.1014568164283454 6.206531846566726 3.2976210873168883 3.038689298289951 0.2012423645269794 1.4227157136858776e-06 0.0421554091664212 0.0268041613697724 5.872310857179041e-07 3.4362632236508183e-06 +Golgi apparatus subcompartment 33 87 3.410610197926057 0.0006481768531556 23.898058252427184 88.56796116504854 0.6438651907142603 0.5157075238910589 9.044082768463602 13.85685287398648 1.2182273227220288 0.3801323692583779 0.0040746783930924 1.0 0.4835958310774439 0.015072680493098 0.0015517901759747 +Microbody membrane 23 33 3.388346329863706 0.0007031541767446 9.83980582524272 26.8373786407767 1.0322166739723002 0.3740701224912098 5.101262737371427 4.075770333088885 1.3138416014090577 0.3534887732287703 5.1586615993248736e-05 1.0 0.4209558173560673 0.1582640101113092 2.282027754593884e-06 +Organelle membrane contact site 10 17 3.313655794286392 0.0009208479041273 6.817961165048544 16.400485436893202 0.815819301321945 0.3904411977369264 3.451940177462974 2.047328298639296 1.2919706717077657 0.3464717655445403 4.66079183403515e-06 0.1553991536419083 0.284754537798848 0.0014099836558107 4.292722219113341e-07 +Golgi stack 17 36 3.247060571190133 0.0011660357112479 9.67233009708738 31.25242718446602 0.7055900861920908 0.4265468940333196 4.557817503574521 5.847941213698429 1.2226912303929196 0.3463938041520717 0.0125249756341189 1.0 0.2391023108133224 0.031009617990344 0.0002407839349748 +Mitochondrion 185 653 3.240427818101507 0.0011935048499478 150.5606796116505 610.75 0.3893280889581553 0.5444893646695418 55.48150839960472 53.47985851692477 2.1394883185001157 0.4272675793576402 6.8855235408448635e-25 1.2329532949664515e-06 4.308151105418245e-12 1.0312520656604152e-16 7.182000486256073e-28 +Golgi cisterna 16 27 3.188679291757716 0.0014292434704601 8.524271844660195 22.490291262135923 0.9086972174309816 0.318868202549777 4.2525712614684625 5.269200019661922 1.391079392561209 0.3149122340418913 0.0017770090297464 1.0 0.1529837701743424 0.0082077294132096 0.0001739282601188 +Transport vesicle 44 97 3.183156678368622 0.0014567876167941 26.046116504854368 92.34708737864078 0.9512017428916244 0.4458616213657612 9.46815354334768 9.09007867686459 1.424803887648301 0.3967491654773343 0.011374709695194 0.3582794844835456 0.1029795528836935 0.2952171384802295 0.0008195615951676 +Transporter complex 28 65 3.086179142587444 0.0020274663104489 16.033980582524272 55.199029126213595 0.256193630237002 0.358562058071074 7.704418772430675 7.665912382074106 1.666161547187811 0.3440522205931707 4.863208262836378e-05 0.000686752050236 0.0028249686746922 0.000238342108926 1.4866223773520345e-07 +Outer mitochondrial membrane protein complex 10 16 3.043275572397294 0.0023401792413957 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 1.8480772151679208e-08 2.1554990909934077e-06 9.726382950516696e-07 5.415752101895563e-06 3.3475114685314166e-10 +Azurophil granule membrane 13 24 3.022889001205189 0.0025037406066943 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 5.007556565391843e-05 1.0 0.356411341728891 0.0244406528674846 5.296294052223938e-05 +Vesicle membrane 91 251 3.0223599487253328 0.0025081211248449 59.03398058252427 252.66747572815535 0.5350285241159404 0.6113983912197217 17.512237349079548 29.567983380691818 1.3292572988488431 0.402876017449685 0.0008648277583896 0.5109691688089031 0.3086417226412262 0.2308081950773884 0.0011574778206896 +Secretory granule membrane 29 72 2.9839508823923744 0.0028455244633245 19.699029126213592 69.8495145631068 0.9295860214656708 0.3887665887416008 7.284889203542463 7.49087955205396 1.5950364553562375 0.3903287060113383 1.890958501769689e-05 0.5851156872439878 0.2475305235196633 0.01231279423043 1.933044153759158e-05 +Coated vesicle 32 92 2.9491574738118382 0.0031864156909295 21.15776699029126 89.28398058252426 0.7996411773181966 0.4463095457932411 7.252509633536616 8.542551157088123 1.3406722753228342 0.3892656029628454 0.000691240447401 0.0718607702735206 0.0122082040687477 0.0034570690223146 0.0002724437609875 +Vacuolar lumen 20 57 2.898889266993521 0.0037448712664232 22.262135922330096 63.33980582524272 0.6562244405592584 0.1887666227175413 6.920437110961116 4.902057024259538 2.8947011026985514 0.298290072492813 0.0001198109701026 0.1054077938723316 0.0964752293748221 0.0001004625143446 3.419848131931248e-05 +Intrinsic component of golgi membrane 7 13 2.8858309660194266 0.0039038176219148 4.655339805825243 10.08495145631068 1.3178763872097854 0.2129685736028588 2.6046347098798024 1.9780511021437377 1.2704958978874823 0.2699640456705705 0.0001605015451872 1.0 0.3312162786192844 0.0004698927732866 0.0007673762167772 +Transport vesicle membrane 22 43 2.844175778873804 0.0044526476035817 12.62135922330097 42.37378640776699 0.5402420874587609 0.5343084089707166 5.404271063272784 4.511161156897919 1.052801184280702 0.3556606283757049 0.0589542411585264 1.0 0.7108948051199993 0.6059548505160635 0.0217982810194937 +Lipid droplet 12 33 2.827395471868264 0.0046928333290336 7.313106796116505 30.72087378640777 0.9597061621709796 0.3916106255858687 3.663189105886808 2.181620314734523 1.1934081113966928 0.3497541884861006 0.0008568840251227 0.2731012734555347 0.4689656122513949 0.2130027955338551 0.0002844504613348 +Endosome 48 203 2.8098445136572097 0.0049565439243224 49.68446601941748 210.85679611650485 0.3589512364806963 0.6263779709054735 15.417095902733692 27.960293924368397 1.2603534839168704 0.3964197633252465 0.0209416972385329 0.9673292887381452 0.3281740234511413 0.2986117618802844 0.0312621869244259 +Endoplasmic reticulum protein containing complex 24 68 2.7753891776791515 0.0055135686534457 20.067961165048544 61.213592233009706 0.544324442160867 0.4875881372361492 7.672624563199495 5.300944201362535 1.5348103009085623 0.3893079894443684 6.413184130901907e-07 0.0149620345130709 0.019444978609395 0.0002712378630867 2.1340526127637558e-10 +Proton transporting two sector atpase complex 10 24 2.6922702588924974 0.0070967411156916 7.116504854368932 22.25728155339806 1.0735578367707936 0.2848832687688338 3.2910616544032156 1.9833825153714253 1.32099194967518 0.2987458873835026 2.88409194608027e-08 0.151306852499084 0.0412617301526311 0.0001415457384854 3.075978788862971e-07 +Er to golgi transport vesicle membrane 18 26 2.6759901934075776 0.0074508825237062 6.495145631067961 21.890776699029125 0.3958870084748403 0.5141628679854253 3.1618901389258056 2.1225127942575894 0.9657155478739712 0.3164691847513972 0.0062137664371764 1.0 0.3439334989552355 0.2871762535363917 0.0002059249337268 +Golgi cisterna membrane 11 20 2.6607532462752816 0.0077966071298141 6.233009708737864 17.101941747572816 0.7930989258143627 0.3092897028410761 3.2184356191878685 3.952300069740005 1.3504727992091758 0.2953094162507478 0.0034356062671048 1.0 0.0874698992517949 0.0362911702166911 0.0007583614663082 +Cis golgi network 12 18 2.647830142976372 0.0081010216893371 5.446601941747573 14.91747572815534 1.304763677188147 0.2415633778835601 2.9087352716231463 3.2280604409731746 1.23405443481851 0.2890539664507128 9.249946893773016e-05 0.1715759324473242 0.0528695758908991 0.0023124348467711 1.12002505888226e-05 +Cytochrome complex 4 16 2.576118848596319 0.0099916296279338 6.021844660194175 16.08495145631068 1.0267019648816196 0.2321293206617183 2.9315837025395948 1.6175814223208935 1.624269406530766 0.2919563386676546 0.0044374904949104 0.1305522111527444 0.0307863463383066 0.0048864602536943 0.0116464914628391 +Nuclear inner membrane 12 22 2.5213087826097604 0.0116919202450151 7.347087378640777 20.57281553398058 1.3204335588742686 0.2519451141048848 3.6006224195129035 1.9968516080603145 1.2188770932171689 0.2896682474252494 0.0001605015451872 0.0172375696548913 0.0603249601752956 0.0032221742646108 0.0007673762167772 +Proton transporting two sector atpase complex proton transporting domain 6 12 2.4976179579132807 0.0125030860098984 4.053398058252427 10.283980582524272 1.020958321179617 0.2307004649223604 1.8491832641634656 1.1862626633334956 1.3576055733210162 0.273185751006507 5.602277818838748e-07 1.0 0.1336663515258769 0.0050923434600555 2.6797087805618226e-06 +Mitochondria associated endoplasmic reticulum membrane 6 10 2.497163398057015 0.0125191255702907 4.191747572815534 9.240291262135925 0.7019541594808174 0.4009163152547425 2.0831338076447135 1.0418560326821893 1.1194321867771957 0.3336055532093068 3.782863969644887e-05 1.0 1.0 0.0086586519898169 1.1673054874396336e-05 +Endoplasmic reticulum tubular network 10 15 2.4809302347224422 0.0131040017761769 4.456310679611651 11.402912621359222 0.7597390036291544 0.4204688348420043 2.5600618129260964 1.9933849978482647 1.110800197793671 0.3406591463359876 8.513542563131137e-07 0.1006582454154426 0.1898352204968973 0.0001476913167928 4.874999040450038e-06 +Proton transporting atp synthase complex 7 13 2.4419346874624863 0.0146087892958559 4.157766990291262 11.08495145631068 0.5328143574617974 0.3012358599713604 2.3610641964760792 1.138499586439592 1.3748267965121657 0.2836171984539964 7.662503280121292e-08 1.0 0.1500965904253892 0.0006143549700213 4.593053333750682e-07 +Snare complex 10 16 2.4279045306314555 0.0151863402509107 6.20873786407767 15.79368932038835 0.8138466711937282 0.3737991711938105 3.1112263618988054 3.010283181947674 1.1802712183474584 0.3261149602927671 0.0232884017791927 1.0 0.0628860756551618 0.0035757213036434 0.0163662094716421 +Azurophil granule 24 64 2.405077347589184 0.016169043142961 20.46359223300971 67.00485436893204 0.4795255752980384 0.3097891700346699 6.177875864944045 5.290582926033595 2.1760997104513735 0.3628132485163926 0.0004353487177938 1.0 0.6689598947070614 0.0595274334568858 3.419848131931248e-05 +Mib complex 7 10 2.3915115958777062 0.0167791539159081 4.669902912621359 10.016990291262136 0.8674199579421746 0.3102009046029466 2.3929035436504367 0.6011337749949848 1.2568635951567688 0.31203902687269 7.965265001886016e-05 0.0017062060788896 0.0002227826640135 0.0001991597833083 7.777797134892854e-07 +Pore complex 5 8 2.282714964372797 0.0224471637380909 3.2111650485436893 8.830097087378642 1.029129610796519 0.2182996080526768 1.893158762220583 0.772882004264421 1.343874754683687 0.2717215815078918 0.0003373424853699 0.0786913117950012 0.0005152543640852 0.0073447144383531 9.60684890252726e-05 +Endoplasmic reticulum exit site 10 19 2.2721732272322432 0.0230760496443236 5.385922330097087 18.1504854368932 0.3312194793480259 0.6462530281079308 2.9377185312287266 1.5600207732253797 0.6907096581503912 0.30511510697369 0.0141003900313116 1.0 1.0 0.0215683584236732 0.0302721435688183 +Trans golgi network 12 58 2.244190908030532 0.0248201207747933 15.419902912621358 63.34466019417476 0.3899535194812628 0.596168565313415 5.947659406670704 9.796108085479462 0.9254595120691144 0.3511819564605877 0.0392013039545989 1.0 0.5625056551404345 0.1042311134375613 0.1567123867326332 +Late endosome 20 63 2.202165047694035 0.0276536520219587 15.655339805825244 65.18203883495146 0.1482522199608934 0.3683478922291265 6.675389202214119 9.543379127098556 1.7080817701484334 0.368772234437858 0.0510772407710494 1.0 0.3096269152871024 0.2264864117738149 0.0102261285355787 +Nadh dehydrogenase complex 14 29 2.181881495869792 0.0291182798422964 7.419902912621359 23.609223300970875 0.690247022635013 0.3818090321561181 3.6908298840900926 3.1049932192976284 1.21822710313397 0.3228613418826432 5.74253368470764e-06 6.0684995779807485e-05 0.000850654769639 1.0205187449327397e-05 9.32963770322802e-07 +Intrinsic component of nuclear inner membrane 5 7 2.1613183394661006 0.0306707572176028 2.4344660194174756 6.461165048543689 0.7221555748366164 0.3746407047127702 1.5973511010756076 0.8763043548183138 1.0289148549650529 0.2984963891905157 0.0017326523156825 1.0 1.0 0.0112385866308786 0.0033785315413713 +Nuclear envelope 34 174 2.139131202362761 0.0324250440207036 37.96116504854369 174.33252427184465 0.0181336977438782 0.7301070934005458 14.47490116343478 13.385385830159189 0.8830829676796945 0.3416784661439265 0.0002203106292455 0.1034003845855936 0.0645302001735257 0.0006949788622503 0.0001192386125399 +Proton transporting atp synthase complex coupling factor f o 4 8 2.0570794856969994 0.0396785806569834 2.388349514563106 6.79126213592233 0.5842994650422648 0.284211882186535 1.5103719705721683 0.8950355849210965 1.3255228108854136 0.2674401609228611 1.715853680785032e-05 1.0 0.0912026913027489 0.0229613270793894 5.279662360650864e-05 +Microbody 31 60 2.0167987873155937 0.0437165155633108 14.5873786407767 55.157766990291265 0.5308798958236631 0.4622505798174944 6.656600193656261 6.967459933597681 1.141402376279513 0.3502304815174672 6.4306344447236566e-06 1.0 0.295605483028919 0.1412576665940389 1.9423868048335755e-06 +Intrinsic component of synaptic vesicle membrane 4 9 1.9998933834877857 0.0455117777809446 3.648058252427184 9.116504854368932 0.724313202500786 0.4129003553732678 2.1933086936710184 1.7154408466980504 1.018214829869002 0.3297596143558817 0.2764791016295673 1.0 1.0 0.4832891613764908 0.3769388356060853 +Nuclear membrane 31 109 1.9670423064474665 0.0491783336216944 24.50485436893204 104.91747572815534 -0.1815376114704942 0.591557416265643 11.339743483004588 8.863746684023472 1.043253069233361 0.3390721291700088 0.0006457180008929 0.1020253064000808 0.0721394229845458 0.0016009507118719 0.000388421299345 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f93997528c4067e95bcfa210a8f29d93f1edcfb2 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 908, + "title": "Average number of proteins per term", + "value": 28.89977973568282 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..83c5bf78dbf0e1a1d946c20bc79287aa24f2ab44 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2560364f9148cb3cd64b585a06288610f066b139 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,274 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Organelle subcompartment 0.6338033875580322 8.271242872809355 1.3256967860462315e-16 1.212812681729905e-13 1.2128126817299784e-13 414 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191 +Nuclear outer membrane endoplasmic reticulum membrane network 0.6383310025790468 8.032058349551383 9.58507618639635e-16 8.712329177244093e-13 4.356164588623943e-13 353 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167 +Endoplasmic reticulum 0.5765387491572085 7.328096100433947 2.334453046341085e-13 2.1196924458532975e-10 7.065641486925681e-11 526 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241 +Mitochondrial envelope 0.5786031056885962 6.90131704283505 5.1522598323161585e-12 4.678252824812099e-09 1.1695632089357681e-09 339 O43169,Q9Y2R0,O75431,Q99595,Q8TBP6,Q9BUK6,O96000,Q9HCL2,Q96A26,Q8WWV3,Q8WUK0,O14949,P45880,Q8N4H5,O95139,Q99536,O43676,Q567V2,P03886,Q86Y39,Q7Z7H8,Q9BUR5,Q8WWI5,Q5XKP0,P09601,Q9UDX5,Q7Z434,Q9NS69,Q9Y277,Q3ZCQ8,Q8N8Q8,P21796,P36551,Q86VD7,Q9H4A6,Q9Y276,Q9NQ50,P20674,Q9H2D1,O95674,Q9Y4W6,Q9H061,Q9NWU5,Q9UBX3,Q9H936,O75208,O75964,P04818,Q969V5,P13073,O75027,Q9UG56,O75323,P57105,Q9NZJ7,Q15070,Q13505,Q9H9B4,O95563,Q9H2V7,Q69YU5,P00846,O14925,P21912,P53701,Q10713,P36542,O00264,Q9Y6C9,Q9Y3B1,O95298,Q7KZN9,Q9BT17,Q9Y6M9,Q9BWH2,Q9HC21,P39210,Q8NBN7,P00403,Q9Y371,Q9Y241,Q6P4A7,Q9P0J0,P62072,Q70HW3,Q9H3K2,Q9H300,Q9NVH1,Q9BXK5,P56378,P03915,P52789,Q6DKK2,P55061,Q9Y320,Q8WWC4,Q12981,Q9UDW1,Q9P0S9,Q07820,Q9Y6N5,O15228,P40939,Q13423,Q96IX5,Q6UXV4,P12235,P24539,Q8N0X7,Q9BQT8,Q8N2A8,Q9BSK2,P56385,Q709F0,P23786,Q9NVI7,Q6NUK1,O96008,P56134,Q9NQZ5,O43615,Q9NX14,Q8IWA4,Q96TC7,O75880,Q96CU9,Q96NB2,P12236,Q5T9A4,Q9BPX6,Q9BUB7,Q9Y512,Q9Y6N1,O95202,Q6PI78,Q16891,Q8NBU5,Q9NPL8,O60313,Q8TB36,Q86Y07,Q9Y375,Q99623,Q16540,P22830,Q8NI60,Q8NAN2,P05141,O75306,O43819,Q53H12,P50416,Q9NR28 153 +Intrinsic component of organelle membrane 0.7011022233448464 6.704341532405862 2.0231657331795735e-11 1.8370345596721562e-08 3.674069153054106e-09 149 O43505,Q9Y2R0,Q9NQC3,O75431,Q99595,O75298,Q9BUR5,Q5XKP0,Q9C0E8,Q8N4V1,P13473,O75844,Q86YN1,P56589,Q8N8Q8,Q9Y282,P20020,Q9NZ01,Q9Y4W6,Q15629,Q969V5,Q9UG56,P57105,Q15070,Q13505,Q9H9B4,Q9UH99,P04439,O95563,O14925,O14975,O95070,Q8NC56,Q6NTF9,Q9H3H5,Q13586,Q9Y679,O00767,Q9NPA0,O60499,Q9BWH2,Q9HC21,Q14739,Q5H8A4,O95470,Q96A33,Q8N2H4,Q6P4A7,Q9P035,Q9H3K2,Q9NVH1,Q9H490,Q16799,O15258,O94901,P42892,Q96BY9,Q8TB61,Q969X5,Q12981,L0R6Q1,Q9Y287,O43292,Q15041,Q7L0J3,Q5SNT2,Q6UXV4,P51572,P12235,O15118,P98194,Q86XL3,Q9GZP9,Q03519,Q6Y1H2,P57088,O43808,O96008,Q8IWA4,O75880,Q96NB2,Q9BPX6,Q9BUB7,Q9Y512,Q9Y6N1,Q16891,Q8TB36,Q9UM00,Q99442,P61619,Q9UKV5,Q92643,Q9UBM7,P27824,O43819,Q9Y4P3,Q53H12,P50416 98 +Envelope 0.5215148914061913 6.289620769937359 3.1824244302942806e-10 2.889640974745682e-07 4.8160689863120115e-08 506 O43169,Q9Y2R0,Q9NQC3,Q99595,O75431,Q9BUK6,Q8TBP6,Q9BVC6,O96000,Q9HCL2,Q96A26,Q8WWV3,Q8WUK0,O14949,P45880,Q8N4H5,O95139,Q99536,O43676,Q567V2,Q7Z3B4,P03886,Q86Y39,Q7Z7H8,Q9H1E5,Q9BUR5,Q8WWI5,Q5XKP0,Q9NXE4,Q9H8M7,P09601,Q9UDX5,O75844,Q7Z434,Q9NS69,Q9Y277,Q3ZCQ8,Q8N8Q8,P21796,P36551,Q86VD7,Q9H4A6,Q9Y276,Q9NQ50,P20674,Q9H2D1,P80303,O95674,Q9Y4W6,Q9H061,Q9NWU5,Q9UBX3,Q9H936,O75208,O75964,P04818,Q969V5,P13073,O75027,Q9UG56,O75323,P57105,Q86UE4,Q9NZJ7,Q15070,Q13505,Q9UH99,Q9H9B4,O95563,Q9H2V7,Q69YU5,P00846,O14925,P21912,P53701,O15173,Q10713,P42167,P36542,O00264,Q9Y6C9,Q9Y3B1,Q99720,O95298,Q7KZN9,Q9BT17,Q9Y6M9,Q9BWH2,Q9HC21,Q9Y6K0,Q14739,P39210,Q8NBN7,P00403,Q9Y371,Q9Y241,Q6P4A7,Q9P0J0,Q9P035,P62072,Q70HW3,Q9H3K2,Q9H300,Q9NVH1,Q8IWB1,Q9BXK5,Q96S66,Q96KC8,P56378,P03915,P52789,O94901,O14657,Q99735,Q6DKK2,P55061,Q9Y320,Q8WWC4,Q12981,Q9UDW1,Q9P0S9,P50402,Q07820,Q9Y6N5,O15228,P40939,Q13423,Q96AG4,Q96IX5,Q5SNT2,Q6UXV4,P12235,O15118,P24539,Q9BTX1,Q8N0X7,Q9BQT8,Q8N2A8,Q9BSK2,P56385,Q709F0,P23786,Q9NVI7,Q6NUK1,P57088,O96008,P56134,O14681,Q9NQZ5,O43615,Q8IXM6,Q9NX14,Q8IWA4,Q96TC7,O75880,Q96CU9,Q96NB2,Q8NFH5,P12236,Q5T9A4,Q9BPX6,Q9BUB7,Q9Y512,Q9Y6N1,O95202,Q6PI78,Q16891,Q8NBU5,Q9NPL8,O60313,Q8TB36,Q86Y07,O15504,Q9Y375,Q12769,Q99623,Q16540,P22830,Q8NI60,P11802,Q9UBM7,Q8NAN2,P05141,O75306,O43819,Q53H12,P50416,Q9NR28 188 +Organelle inner membrane 0.5767693854660976 6.15150746463608 7.674991328165669e-10 6.96888970945642e-07 9.955560192934896e-08 265 Q9Y2R0,O75431,Q99595,Q8TBP6,O96000,Q8WUK0,O14949,O95139,O43676,Q567V2,P03886,Q86Y39,Q7Z7H8,Q9H1E5,Q9BUR5,Q5XKP0,Q9UDX5,O75844,Q3ZCQ8,Q8N8Q8,P36551,Q9Y276,Q86VD7,Q9NQ50,P20674,Q9H2D1,Q9Y4W6,Q9NWU5,Q9H061,O95674,Q9UBX3,Q9H936,O75208,P04818,O75964,P13073,O75027,Q9UG56,Q15070,Q13505,Q9H9B4,Q9UH99,O95563,Q9H2V7,Q69YU5,P00846,O14925,P21912,P53701,Q10713,P36542,Q9Y6C9,Q99720,O95298,Q7KZN9,Q9BT17,Q9Y6M9,Q9HC21,Q14739,P39210,Q8NBN7,P00403,Q9Y241,Q6P4A7,Q9P0J0,P62072,Q70HW3,Q9H3K2,Q9H300,Q9NVH1,P56378,P03915,O94901,Q6DKK2,Q8WWC4,Q9UDW1,P50402,Q9Y6N5,P40939,Q13423,Q96IX5,Q5SNT2,Q6UXV4,P12235,P24539,Q9BQT8,Q9BSK2,P56385,Q709F0,P23786,Q9NVI7,Q6NUK1,O96008,P56134,O43615,Q8IXM6,Q9NX14,O75880,Q96CU9,Q96NB2,P12236,Q5T9A4,Q9BPX6,Q9BUB7,Q9Y512,Q9Y6N1,O95202,Q6PI78,Q16891,Q9NPL8,O60313,Q9Y375,Q99623,Q16540,P22830,Q8NI60,P05141,O75306,O43819,Q53H12 120 +Golgi membrane 0.6136080552852924 5.55617979250436 2.7574285145637284e-08 2.503713782397468e-05 3.129681364143331e-06 141 O43505,O95197,P24390,Q99640,Q6IQ22,Q13190,P61019,Q9BUR5,Q9NXE4,Q8N4V1,P17302,Q9H4A6,Q9Y282,O14653,Q8NCH0,Q16706,O00461,Q9P2W9,P04439,Q9HD26,O43731,Q10713,O95070,Q6NTF9,Q92896,Q9Y3E0,Q93063,Q9BXS4,Q11206,Q8NF37,O60499,Q96JB2,Q7LGA3,Q9Y371,Q8N2H4,Q9H3P7,Q14108,O15027,Q9Y5U9,Q16799,Q96S66,O75396,O15258,P10321,Q8TB61,Q969X5,O95249,L0R6Q1,Q9Y287,Q10472,Q15392,Q9BVK6,Q9H7Z7,Q9Y3B3,P51572,Q8IV08,P98194,P49755,P62820,P35613,Q7Z3C6,P61026,Q16739,P49257,O15260,Q9NTJ5,Q8N4A0,Q10469,Q8TBA6,P48739,P51790,Q9UM00,Q14789,Q9H0U4,Q15363,Q12770,P15291,O15498 78 +Membrane protein complex 0.4968130860215518 5.150585095208843 2.596750782640327e-07 0.0002357572065794 2.6198330118294407e-05 299 P67812,O75431,Q99595,O96000,Q15904,O14949,P45880,O95139,Q9UNK0,Q8N4H5,O43676,Q13190,P03886,Q86Y39,Q9BUR5,Q8N511,Q5XKP0,Q8N4V1,P46977,Q3ZCQ8,Q9NS69,Q9Y277,P17302,P21796,Q9Y276,P20674,O75964,O14653,P13073,Q9Y5M8,Q9P2W9,Q13505,Q9C0H2,Q93050,P00846,O14925,P21912,P36542,Q6NTF9,Q15005,O95298,Q9NPA0,Q9Y6M9,O60499,P00403,Q9P0J0,P62072,Q53GQ0,Q9NVH1,Q9H490,Q96S66,P56378,P03915,P63218,O94901,Q9NR31,Q9UBV2,O95249,Q12981,Q9UDW1,Q9Y487,O43292,Q9Y3B3,Q4KMQ2,Q15041,Q96IX5,P41440,Q6UXV4,P12235,O75340,P24539,Q8TCJ2,P49755,P56385,Q9GZP9,Q03519,O96008,Q9H0U3,P56134,Q9NX14,Q8IWA4,Q96CU9,P12236,Q9BPX6,Q9Y512,P51571,Q16891,Q8N2K0,Q9UBU6,Q96CS3,O15269,O14678,Q9Y375,P51798,P61619,Q99623,Q9UKV5,Q92643,O15400,Q9UGP8,P05141,P05023,O75306,Q53H12,O15498,Q9NR28 106 +Golgi apparatus 0.4879741934362068 5.092438441021567 3.534875032465702e-07 0.0003209152053738 3.067960402344783e-05 310 O43505,O95197,P24390,Q99640,Q9UNK0,Q96RQ1,Q6IQ22,Q13190,Q9BSL1,P61019,P50897,Q9BUR5,Q9NXE4,Q8N4V1,Q4J6C6,P17302,Q9H4A6,Q92520,Q96A57,Q9Y282,P80303,O14653,Q5VW38,Q8NCH0,Q16706,Q8WVQ1,O00461,Q9P2W9,Q9Y6Y8,Q02818,Q8TAD4,P04439,Q9HD26,Q93050,Q7Z3D4,Q7Z5K2,O14773,O43731,P04062,Q10713,O95070,Q9NX62,Q13636,P53634,Q6NTF9,Q92896,Q9Y3E0,Q93063,Q9BXS4,Q9NX40,Q11206,Q8NF37,O60499,Q9Y6K0,Q7LGA3,Q7RTS9,Q9Y371,Q8N2H4,Q14108,Q16799,Q96S66,Q96PU5,O14828,O15258,Q9Y3A6,Q9NPR9,Q9NR31,Q8TB61,Q969X5,O95249,L0R6Q1,Q9Y287,Q10472,Q92544,Q15392,Q9BVK6,Q9H7Z7,Q9Y3B3,O75503,Q9BSR8,Q9NQX7,P51572,Q8IV08,O14735,O15118,P98194,O14966,P49755,Q8N2A8,P62820,P35613,Q7Z3C6,P61026,O14681,Q16739,P49257,O15260,Q9NTJ5,Q8N4A0,Q10469,Q8TBA6,Q9BRK5,P48739,P51790,Q9UM00,Q14789,Q9H0U4,O43852,Q9UKV5,Q15363,O43823,Q12770,P15291,P05023,O15498 115 +Outer membrane 0.6526199562755408 5.082923606690314 3.716692117368042e-07 0.0003374187684514 3.067960402344783e-05 91 O43169,O75431,P50402,Q07820,Q9BUK6,Q9BVC6,Q99720,Q9HCL2,Q8WWV3,Q9Y512,P45880,Q8N4H5,Q99536,Q9BWH2,Q16891,Q8NBU5,Q9BUR5,Q8WWI5,Q9NXE4,Q5XKP0,P09601,Q9Y371,Q6UXV4,O60313,Q9NS69,Q9Y277,Q8TB36,P21796,Q9NVH1,Q8N0X7,Q8IWB1,Q8N2A8,Q99623,Q969V5,P57105,Q9NZJ7,Q13505,P52789,Q9UBM7,O96008,Q8NAN2,Q53H12,P50416,Q9NQZ5,O00264,Q8IWA4,Q96TC7,Q9Y6C9 48 +Intrinsic component of endoplasmic reticulum membrane 0.6878867218816276 4.662499831724179 3.123913425051583e-06 0.002832498704791 0.0002363761158289 65 Q9H3H5,Q9NQC3,O00767,O43292,Q9NPA0,Q5H8A4,O75298,O95470,Q15041,Q8N4V1,P51572,Q96A33,O75844,Q86YN1,Q9P035,Q9UM00,Q9Y282,Q9NZ01,Q99442,Q15629,Q9H490,P61619,Q16799,Q86XL3,Q9GZP9,Q9UKV5,Q03519,Q6Y1H2,Q92643,P57088,Q9UBM7,Q96BY9,P27824,Q8TB61,Q969X5,Q12981,Q6NTF9 37 +Inner mitochondrial membrane protein complex 0.6242092051327482 4.5491741714154 5.3856853852174424e-06 0.0048782778616936 0.0003260134886518 83 Q96CU9,O75431,Q99595,O95298,P12236,O96000,Q9BPX6,Q9Y6M9,Q9Y512,O14949,O95139,O43676,Q16891,P03886,Q86Y39,Q96IX5,Q9BUR5,Q5XKP0,P00403,Q6UXV4,Q3ZCQ8,Q9P0J0,P62072,P24539,Q9Y276,P20674,Q9NVH1,Q9Y4W6,Q9Y375,O75964,P56385,Q99623,P13073,P56378,P03915,Q13505,Q9Y5J6,P00846,O14925,P21912,Q53H12,P56134,O75306,O95169,P36542,Q9UDW1,Q9NX14 47 +Intrinsic component of mitochondrial membrane 0.6936265076236289 4.44177998697921 8.92177590339216e-06 0.0080682839148207 0.0005063107825175 50 Q9Y2R0,Q96NB2,O75431,Q99595,Q9BPX6,Q9BUB7,Q9Y512,Q9Y6N1,Q9BWH2,Q9HC21,Q16891,Q9BUR5,Q5XKP0,Q6UXV4,P12235,Q6P4A7,Q8TB36,Q8N8Q8,Q9H3K2,Q9NVH1,Q9Y4W6,Q969V5,Q9UG56,P57105,Q15070,Q13505,Q9H9B4,O96008,O14925,Q8IWA4,O43819,Q53H12,P50416,O75880 34 +Intrinsic component of mitochondrial inner membrane 0.7505695949840228 4.090142574715322 4.311080978358639e-05 0.0383891760585008 0.0020602429096577 32 Q9Y2R0,Q96NB2,O75431,Q99595,Q9Y512,Q9Y6N1,Q9HC21,Q16891,Q9BUR5,Q5XKP0,Q6UXV4,Q6P4A7,Q8N8Q8,Q9H3K2,Q9NVH1,Q9Y4W6,Q9UG56,Q15070,Q13505,Q9H9B4,O14925,O43819,Q53H12,O75880 24 +Endoplasmic reticulum golgi intermediate compartment 0.6394787023216643 4.030395673086832 5.568303972935951e-05 0.0493046433806586 0.0025280100037129 53 P24390,Q15904,Q9BVK6,Q96RQ1,Q13190,Q9Y3B3,Q8N511,P51572,Q9Y282,Q14789,P80303,Q9H0U4,P49755,O14653,Q03519,Q15363,O15258,Q02818,Q3ZAQ7,Q9Y3A6,O15498,O95070,Q969X5,P49257,O15260,Q10472 26 +Endoplasmic reticulum golgi intermediate compartment membrane 0.7729329308759594 3.9945329588761 6.482190418188871e-05 0.0571614281435353 0.0028027756665312 29 P24390,Q15904,Q9BVK6,Q96RQ1,Q13190,Q9Y3B3,Q8N511,P51572,Q9Y282,Q9H0U4,P49755,O14653,Q03519,Q15363,Q3ZAQ7,Q9Y3A6,O15498,O95070,Q969X5,P49257,O15260,Q10472 22 +Intrinsic component of plasma membrane 0.5653670336600044 3.9256986883897143 8.647835303587925e-05 0.0755217364395252 0.0035691974798445 82 Q13586,Q9UIQ6,O43657,Q00325,P27105,O60637,P14672,Q9UNK0,Q08722,Q9BRK0,O96005,Q8N2K0,Q9BTU6,P41440,P51790,P51572,Q02978,P12235,O15118,Q8TDW0,P17302,P36551,P20020,P11279,P30825,P23634,Q9H2J7,P35613,Q13641,Q15043,Q9H1Z9,P10321,Q8TAD4,P04439,P16615,Q96QD8,Q8NAN2,Q9UJS0,Q9H0U3,P55061,Q92542,P27824,P05141,P05023,O15498,O95864,O00264,Q8WTV0,Q9NR28 49 +Vacuole 0.4389390759854701 3.7895248907482473 0.0001509356878524 0.1280820455637072 0.0058993234190029 206 Q969Q5,Q9UM22,Q9Y679,Q9UIQ6,O95298,Q9Y487,Q9BXS4,P27105,Q9HBH5,Q9NX40,Q07065,Q8NF37,Q9UNK0,Q99536,Q8NCG7,Q6IQ22,P10253,Q9H7Z7,P61019,Q9BTU6,Q9BTY2,P50897,P41440,O75503,Q8N511,Q9NQX7,P51790,Q96CS3,P13473,Q9UHG3,Q9Y371,Q8IV08,P11117,O15118,Q14108,Q9Y6I9,P17900,Q96A57,O14678,P11279,O14966,P15586,P51798,P38435,O43681,Q15043,Q9NZJ7,O15400,Q15165,Q3ZAQ7,Q9H2V7,Q9HD26,P42892,Q93050,Q9UMX0,Q9H0B6,Q7Z3C6,O14773,P04062,P10619,Q9H0U3,P15291,P42785,P07602,P08236,Q8NFG4,Q13510,O15260,P53634,Q8WTV0 70 +Copii coated er to golgi transport vesicle 0.658816703214667 3.781431303188109 0.0001559292533657 0.1320271136458439 0.0058993234190029 39 Q9BVK6,Q96RQ1,Q13190,Q9Y3B3,O75340,Q9Y282,O15027,P49755,Q9Y5U9,O14653,O75396,Q15363,Q9Y6B6,Q9Y6Y8,P04439,Q3ZAQ7,Q9Y3A6,Q12770,Q9NR31,O95070,P49257,Q969X5,P53634 23 +Vacuolar membrane 0.4731862813255933 3.5795638371681 0.0003441681678715 0.2684271589668523 0.0122078454575893 120 Q9UIQ6,O95298,Q9Y487,Q9BXS4,P27105,Q9HBH5,Q07065,Q8NF37,Q9UNK0,Q6IQ22,Q8NCG7,P10253,P61019,Q9BTU6,P41440,O75503,Q8N511,Q9NQX7,P51790,P13473,Q9Y371,Q8IV08,P11117,O15118,Q14108,Q9Y6I9,O14678,P11279,P51798,Q15043,Q9NZJ7,O15400,Q9H2V7,Q9HD26,P42892,Q93050,Q7Z3C6,Q9H0B6,P04062,P10619,Q9H0U3,P15291,P42785,P07602,Q8NFG4,O15260,Q8WTV0 47 +Respirasome 0.5915444043966611 3.565611619176036 0.0003630086204349 0.2808401820052797 0.0122078454575893 49 Q96CU9,O95298,Q7KZN9,O96000,Q9Y6M9,O14949,O95139,O43676,Q13423,P03886,Q86Y39,P00403,Q9Y241,Q9P0J0,Q9Y276,P20674,Q9Y375,P13073,P03915,Q6DKK2,P21912,O75306,O95169,Q9UDW1,Q9NX14 25 +Mitochondrial protein containing complex 0.4348802865615061 3.5135249084324744 0.0004422029514037 0.3307576870949071 0.0143400099955211 164 Q96CU9,O75431,Q99595,O95298,P12236,O96000,Q9BPX6,Q9Y6M9,Q9Y512,O14949,O95139,Q8N4H5,O43676,Q567V2,Q16891,P40939,P03886,Q86Y39,Q7Z7H8,Q96IX5,Q9BUR5,Q5XKP0,P00403,Q6UXV4,P12235,Q3ZCQ8,Q9NS69,Q15118,Q9P0J0,P21796,Q9Y276,P62072,P24539,Q9NQ50,P20674,Q9NVH1,Q9Y4W6,Q9Y375,O75964,P56385,Q99623,P13073,P56378,Q16540,P03915,Q13505,P00846,O96008,O14925,P21912,Q53H12,P56134,P05141,O75306,P36542,Q9UDW1,Q9NX14,Q8IWA4 58 +Lysosomal lumen 0.6667218207787754 3.427780745859928 0.0006085367226296 0.4246170939666616 0.0162515101219909 31 P50897,Q9UM22,O14773,P38435,P04062,P13473,Q8IV08,P10619,P11117,O43681,P07602,P08236,Q14108,Q9NZJ7,Q13510,P17900 16 +Golgi apparatus subcompartment 0.5064603393280203 3.410610197926057 0.0006481768531556 0.4449712726673767 0.0168155595047239 87 Q9BXS4,Q10469,Q8TBA6,Q11206,Q9UNK0,O60499,Q96JB2,Q9BSR8,Q9NXE4,P51572,Q8N2H4,Q4J6C6,Q9H4A6,Q96A57,Q14789,P98194,O14966,Q16706,Q8WVQ1,Q15363,O00461,O14828,P04439,Q7Z3C6,P61026,Q9NPR9,P04062,Q10713,P15291,O95249,Q9NX62,Q13636,Q10472 33 +Microbody membrane 0.6428309014724274 3.388346329863706 0.0007031541767446 0.4720156136793314 0.0177351109023361 33 Q15067,O15228,Q8WVX9,Q8NBU5,P40855,P39210,Q9NR77,Q7Z434,P56589,Q8TB36,Q5T8D3,P51648,O14678,P50542,P28288,Q6IAN0,O96011,O43808,O75381,Q9Y3D6,O14975,P04035,P33121 23 +Organelle membrane contact site 0.7746374163271198 3.313655794286392 0.0009208479041273 0.5667823873858536 0.0194448813243643 17 Q96JX3,O96008,Q5XKP0,Q96BY9,Q9NTJ5,P51572,Q96S66,Q9Y320,Q96N66,Q96TC7 10 +Golgi stack 0.602525098083908 3.2470605711901332 0.0011660357112479 0.6533286903246853 0.0217735414137431 36 P51572,Q9BXS4,Q16706,Q10469,Q8TBA6,Q8WVQ1,P15291,Q11206,Q15363,Q10713,O00461,O95249,Q9H4A6,Q14789,P98194,Q10472,P04439 17 +Mitochondrion 0.3760576452444062 3.240427818101507 0.0011935048499478 0.6618783783357391 0.0217735414137431 653 O43169,Q9Y2R0,O75431,Q99595,Q8TBP6,Q9BUK6,O96000,Q9HCL2,Q96A26,Q9UHQ9,Q8WWV3,Q8WUK0,O14949,P45880,Q8N4H5,O95139,Q99536,O43676,Q567V2,Q68CZ6,P03886,Q86Y39,Q7Z7H8,Q9BUR5,Q8WWI5,Q5XKP0,P09601,Q9UDX5,Q7Z434,Q9NS69,Q9Y277,Q3ZCQ8,Q8N8Q8,P21796,Q15118,Q86VD7,Q9H4A6,P17302,P36551,Q9Y276,Q9H2D1,Q9NQ50,P20674,O95674,Q9Y4W6,Q9H061,Q9NWU5,Q9UBX3,Q9H936,O75208,O75964,P04818,Q5TC12,Q969V5,P13073,O75027,Q9UG56,P57105,Q9NZJ7,Q15070,Q13505,Q15165,Q9H2V7,Q69YU5,Q9H0B6,P00846,O14925,P21912,P53701,Q10713,P36542,Q9H6K4,O00264,Q9H1A3,Q9Y6C9,Q9Y3B1,O95298,Q7KZN9,Q9BT17,Q9Y6M9,Q9BWH2,Q9HC21,P39210,Q8NBN7,P00403,Q9Y371,Q9Y241,Q6P4A7,Q9P0J0,P62072,Q70HW3,Q9H3K2,Q9H300,Q9NVH1,Q3SXM5,Q8N2F6,Q9BXK5,P56378,P03915,Q9NPH0,P52789,Q6DKK2,P55061,Q9Y320,Q8WWC4,Q12981,Q9UDW1,Q9P0S9,Q07820,Q9Y6N5,O43292,Q9H7Z7,O15228,P40939,Q13423,Q96AG4,Q96IX5,Q6UXV4,P51572,Q9NR77,P12235,P24539,Q8NBX0,Q16836,O14966,Q8N0X7,Q9BQT8,Q8N2A8,Q96JX3,Q9BSK2,P56385,P35613,Q709F0,P23786,Q8IXJ6,Q9NVI7,Q6NUK1,Q9NQH7,Q7Z3C6,O96008,P48723,P56134,Q9NQZ5,O43615,P51530,Q9NX14,Q8IWA4,P16435,Q96TC7,O75880,Q96CU9,Q96NB2,P12236,Q5T9A4,Q9BPX6,Q9BUB7,Q9Y512,Q9Y6N1,O95202,Q6PI78,O75648,Q16891,Q8NBU5,Q9NPL8,P35610,O60313,Q8TB36,Q86Y07,Q9Y375,Q99623,Q16540,P22830,P00367,Q8NI60,O43823,Q9NWS8,Q8NAN2,P05141,O75306,O43819,Q9Y2W6,Q53H12,P50416,O15498,Q9NR28 185 +Golgi cisterna 0.6741546485293246 3.188679291757716 0.0014292434704601 0.7271085981428379 0.0249567898303424 27 P51572,Q9BXS4,Q16706,Q8WVQ1,Q8TBA6,P15291,Q10713,Q11206,Q15363,O95249,O00461,Q9H4A6,Q96JB2,P98194,Q10472,P04439 16 +Transport vesicle 0.4636342102464025 3.183156678368622 0.0014567876167941 0.7338586140550148 0.0249577953971522 97 P24390,Q8TBA6,Q9BVK6,O60499,Q6IQ22,Q13190,Q9Y3B3,Q7L0J3,P50897,O43760,P51790,O75340,Q14141,Q96A57,P20020,P11279,O15027,P49755,Q9H0U4,O14653,P62820,O75396,Q15363,O00461,Q9Y6B6,Q9Y6Y8,P10321,O15400,P04439,Q86Y82,Q3ZAQ7,Q9HD26,P61026,Q12770,O43731,Q9NR31,Q9BT78,Q92905,Q92542,O15498,O95249,P49257,O15260,O76024 44 +Transporter complex 0.519517002470963 3.0861791425874436 0.0020274663104489 0.8416279326300389 0.0296124097626551 65 Q96CU9,O95298,O96000,Q9BPX6,Q9Y6M9,O14949,O95139,O43676,Q8N2K0,P03886,Q86Y39,Q4KMQ2,Q9P0J0,P62072,Q9Y276,O14678,Q9Y375,P51798,Q96S66,P03915,Q9C0H2,Q9Y5J6,O75381,P05023,O75306,O95169,Q9UDW1,Q9NX14 28 +Outer mitochondrial membrane protein complex 0.7535259795623258 3.043275572397294 0.0023401792413957 0.8808501030353103 0.0330564574081704 16 Q13505,Q9BUR5,Q5XKP0,O96008,Q6UXV4,Q9NS69,Q9Y512,Q8N4H5,Q8IWA4,Q9NVH1 10 +Azurophil granule membrane 0.6756669046754231 3.022889001205189 0.0025037406066943 0.8973312228028383 0.0339906564381978 24 Q9NQX7,O95298,P13473,Q9H0U3,P27105,P15291,Q07065,P42785,Q8NF37,P07602,Q9NZJ7,O15260,P11279 13 +Vesicle membrane 0.3898553486595801 3.0223599487253328 0.0025081211248449 0.8977397997061932 0.0339906564381978 251 P24390,Q15904,Q9UHQ9,Q9UNK0,Q6IQ22,Q13190,Q8N511,O43760,Q8N4V1,P13473,P30519,P17302,P20020,O14653,Q92543,O00461,Q9Y6Y8,Q9NZJ7,Q9UH99,P04439,Q8TAD4,Q9HD26,Q93050,O43731,O14975,Q96JJ7,P42785,P07602,O00264,Q13636,Q969Q5,O95298,Q9BXS4,P27105,Q8NF37,O60499,P10253,Q86YV9,Q13546,Q9BXB4,Q14108,O15027,O75396,Q9Y6B6,O14828,P10321,Q86Y82,P42892,O14964,Q9NR31,Q92542,Q14728,Q9Y287,Q8WTV0,O76024,Q9BRG1,Q9Y487,Q96RL7,Q07065,Q08722,Q9Y3B3,Q4KMQ2,Q7L0J3,Q9NQX7,Q8IV08,O15118,O75340,P11279,P49755,P62820,P35613,Q03519,Q15043,Q7Z3C6,P61026,Q9H0U3,P49257,O15260,O60831,Q9UIQ6,Q5T9A4,P51790,Q96HR9,Q658P3,Q15363,O15400,Q3ZAQ7,Q12770,P15291,A4D1P6,O15498 91 +Secretory granule membrane 0.4978997385180079 2.9839508823923744 0.0028455244633245 0.9247861014099308 0.0369105173242668 72 Q969Q5,O95298,Q5T9A4,P27105,Q9UHQ9,Q07065,Q8NF37,Q08722,Q4KMQ2,Q9NQX7,P13473,P30519,P11279,P49755,P35613,Q15363,Q9NZJ7,Q8TAD4,P61026,Q93050,O14975,Q9H0U3,P15291,Q13636,Q96JJ7,P42785,P07602,O00264,O15260 29 +Coated vesicle 0.4564137336785796 2.9491574738118382 0.0031864156909295 0.9448602736403462 0.0395920937846413 92 P24390,Q9BVK6,Q96RQ1,Q13190,Q9Y3B3,Q8N511,P51572,O75340,Q14108,Q96HR9,Q9Y282,O15027,P49755,Q9Y5U9,O14653,Q5VW38,O75396,Q15363,Q9Y6B6,Q9Y6Y8,P04439,Q3ZAQ7,Q9HD26,P42892,Q9Y3A6,Q12770,O43731,Q9NR31,O95070,P49257,Q969X5,P53634 32 +Vacuolar lumen 0.5115438983644298 2.898889266993521 0.0037448712664232 0.9668504445877426 0.0430423178469907 57 Q9UM22,Q9H7Z7,Q99536,Q9BTY2,P50897,Q96CS3,P13473,Q8IV08,P11117,Q14108,P17900,P38435,O43681,Q9NZJ7,O14773,P04062,P10619,P07602,P08236,Q13510 20 +Intrinsic component of golgi membrane 0.7965572273147308 2.8858309660194266 0.0039038176219148 0.9713213784014738 0.0438993367236692 13 Q8TB61,Q8N2H4,O95070,Q969X5,L0R6Q1,O15258,Q9Y282 7 +Transport vesicle membrane 0.532145771098001 2.8441757788738036 0.0044526476035817 0.982612989397631 0.0481310002863363 43 O60499,Q13190,Q9Y3B3,Q7L0J3,O43760,O75340,P20020,O15027,P49755,O14653,P62820,O75396,Q15363,Q9Y6B6,Q9Y6Y8,P10321,P04439,Q86Y82,Q3ZAQ7,Q12770,Q9NR31,P49257 22 +Lipid droplet 0.571040393947533 2.827395471868264 0.0046928333290336 0.9860339005307244 0.0496862966136242 33 Q8N0X7,Q99720,Q96CS3,P51572,Q07065,Q8NF37,Q8NBX0,Q8NBQ5,Q6UX53,Q9H1P3,Q01105,Q9H6V9 12 +Endosome 0.3814846907501405 2.8098445136572097 0.0049565439243224 0.9890205775342285 0.0511425214009632 203 Q969Q5,Q92544,O60831,Q9UIQ6,Q9Y487,Q9BXS4,Q15904,Q9NX40,Q9UNK0,Q9BRK5,P41440,Q8N4V1,P51790,Q8IV08,O15118,O75340,Q14108,Q9H4A6,Q96A57,P11279,O14966,Q8IZ07,O14653,Q5VW38,Q658P3,Q92543,P62820,Q9GZP9,P35613,O00461,Q96PU5,Q15043,Q9NZJ7,O14828,O15400,P23458,P42892,Q93050,Q7Z3C6,P61026,P31751,O14773,P07602,A4D1P6,Q13510,Q9Y287,Q9NWW5,O15498 48 +Endoplasmic reticulum protein containing complex 0.4851205674545374 2.7753891776791515 0.0055135686534457 0.993396613287169 0.055625781525875 68 P67812,O43292,Q9NPA0,P51571,Q15041,Q9UBU6,Q8N4V1,Q96CS3,P46977,O15269,Q53GQ0,Q8TCJ2,Q9H490,P61619,Q9GZP9,Q9UKV5,Q03519,O43681,Q9Y5M8,Q92643,Q9H0U3,Q9UBV2,Q6NTF9,Q15005 24 +Proton transporting two sector atpase complex 0.6267544278666397 2.6922702588924974 0.0070967411156916 0.998445831846804 0.0644384093304806 24 Q93050,Q8N511,P00846,O75964,Q9Y487,P56385,P56378,P24539,P36542,Q96IX5 10 +Er to golgi transport vesicle membrane 0.6095777337810252 2.6759901934075776 0.0074508825237062 0.9988758536550184 0.0669841715992605 26 P49755,Q12770,O14653,Q9NR31,O95486,O75396,O75340,P55735,Q15363,Q9Y6B6,Q9Y6Y8,Q13190,Q9Y3B3,P10321,P49257,P04439,Q3ZAQ7,O15027 18 +Golgi cisterna membrane 0.6504252264748677 2.6607532462752816 0.0077966071298141 0.9991807005377767 0.0682772337820522 20 P51572,Q8WVQ1,P15291,Q10713,Q11206,Q15363,O00461,Q9H4A6,Q96JB2,P98194,Q10472 11 +Cis golgi network 0.6607701957624383 2.647830142976372 0.0081010216893371 0.9993799336336135 0.0687451186347487 18 P49755,Q9Y3A6,Q9NPR9,O43731,Q16706,P24390,Q8TBA6,O95249,O00461,Q14789,P98194,O14966 12 +Cytochrome complex 0.6734065569591804 2.576118848596319 0.0099916296279338 0.9998903292561848 0.081003568769321 16 Q7KZN9,P13073,O14949,P00403 4 +Nuclear inner membrane 0.6158724508474283 2.5213087826097604 0.0116919202450151 0.9999769723264936 0.0893003746309777 22 P50402,Q9BTV4,Q99720,Q5SNT2,P62995,O75844,Q8IXM6,Q8NC56,Q9UH99,Q14739,O94901,Q9H1E5 12 +Proton transporting two sector atpase complex proton transporting domain 0.7435333750916296 2.4976179579132807 0.0125030860098984 0.999989074071312 0.0931751312936396 12 Q93050,P00846,O75964,P56385,Q9Y487,P24539 6 +Mitochondria associated endoplasmic reticulum membrane 0.7800844267268479 2.497163398057015 0.0125191255702907 0.9999892340292528 0.0931751312936396 10 Q96JX3,O96008,P51572,Q96S66,Q9Y320,Q96N66 6 +Endoplasmic reticulum tubular network 0.6790247290536005 2.4809302347224422 0.0131040017761769 0.9999937133358552 0.0958109683692312 15 P61026,Q00765,Q13586,Q9NQC3,P50402,Q9C0E8,Q8NHH9,Q9H6H4,Q6NUK4,Q9BRK0 10 +Proton transporting atp synthase complex 0.7132518252838644 2.4419346874624863 0.0146087892958559 0.99999842715736 0.1044470919735213 13 P00846,O75964,P56385,P56378,P24539,P36542,Q96IX5 7 +Snare complex 0.6489389613293315 2.4279045306314555 0.0151863402509107 0.9999990763872294 0.1070262142719816 16 O14653,O75396,Q9UNK0,O60499,O95249,Q12981,Q9P2W9,Q13190,O15400,O15498 10 +Azurophil granule 0.4561164722557269 2.4050773475891836 0.016169043142961 0.9999996269223111 0.112072451708463 64 O95298,P27105,Q07065,Q8NF37,Q99536,Q9H7Z7,Q9BTY2,Q9NQX7,Q96CS3,P13473,P17900,P11279,P15586,O43681,Q9NZJ7,O15400,Q9H0U3,P10619,P15291,P42785,P07602,P08236,P53634,O15260 24 +Mib complex 0.7589321834036661 2.3915115958777062 0.0167791539159081 0.9999997875881916 0.1141286837440581 10 Q9BUR5,Q5XKP0,Q6UXV4,Q9Y512,Q16891,Q13505,Q9NVH1 7 +Triglyceride rich plasma lipoprotein particle 0.9874843554443052 2.332637793595049 0.0196671636016394 0.9999999853045436 0.1275556039306329 2 Q9BUR5 1 +Pore complex 0.7682420540302415 2.282714964372797 0.0224471637380909 0.9999999988848378 0.1425316410782279 8 O96008,P12235,Q9Y277,P45880,P21796 5 +Endoplasmic reticulum exit site 0.5969144261862207 2.2721732272322432 0.0230760496443236 0.9999999993783194 0.1448960436652417 19 Q9Y3A6,Q96PC5,Q9NR31,O95486,Q9HCU5,O75340,Q9Y6B6,Q5JRA6,P04439,O15027 10 +Trans golgi network 0.4470478193655442 2.244190908030532 0.0248201207747933 0.999999999877274 0.1533106779830772 58 Q7Z3C6,Q9BSR8,Q9NPR9,P04062,Q8N2H4,O60499,Q9NX62,Q9H4A6,O14828,Q96A57,P98194,O14966 12 +Late endosome 0.4386686374688325 2.202165047694035 0.0276536520219587 0.9999999999912612 0.1696588921347201 63 Q9BXS4,Q9UNK0,Q9BRK5,P51790,Q8IV08,O15118,Q14108,Q96A57,P11279,Q8IZ07,O14653,Q658P3,Q9GZP9,Q96PU5,Q15043,Q9NZJ7,O15400,Q7Z3C6,P07602,A4D1P6 20 +Nadh dehydrogenase complex 0.5219381533698653 2.1818814958697916 0.0291182798422964 0.9999999999977766 0.1739434085316128 29 Q96CU9,Q9Y375,O95298,O96000,O75306,Q9Y6M9,Q9P0J0,P03915,O95169,O95139,O43676,Q9NX14,P03886,Q86Y39 14 +Intrinsic component of nuclear inner membrane 0.7960780702132594 2.1613183394661006 0.0306707572176028 0.99999999999948 0.1773824684941615 7 Q5SNT2,Q8NC56,Q9UH99,Q14739,O94901 5 +Nuclear envelope 0.3433900689652183 2.139131202362761 0.0324250440207036 0.9999999999998996 0.1845681576020049 174 Q9NQC3,P50402,Q99720,Q8NFH5,Q9Y6K0,Q7Z3B4,Q14739,Q96AG4,Q9H1E5,Q5SNT2,O75844,O15118,Q9P035,Q86Y07,Q9BTX1,P80303,O15504,Q8IWB1,Q12769,Q96S66,Q96KC8,Q86UE4,O94901,Q9H2V7,P11802,O14657,P57088,Q99735,O15173,P56134,O14681,P42167,Q12981,Q8IXM6 34 +Proton transporting atp synthase complex coupling factor f o 0.7222172472375628 2.0570794856969994 0.0396785806569834 1.0 0.2080553175070161 8 P56385,P24539,P00846,O75964 4 +Microbody 0.4245632446575713 2.0167987873155937 0.0437165155633108 1.0 0.224263254980148 60 Q15067,O15228,P08670,Q8WVX9,Q8NBU5,P40855,P39210,Q9NR77,Q7Z434,P56589,Q8TB36,Q5T8D3,P51648,O14678,P50542,P28288,Q9NQG6,Q969V5,O15254,Q709F0,Q8N4Q0,Q6YN16,Q6IAN0,O96011,O43808,O75381,Q9Y3D6,O14975,Q96CN7,P04035,P33121 31 +Intrinsic component of synaptic vesicle membrane 0.6969447517342426 1.9998933834877857 0.0455117777809446 1.0 0.2306296726933716 9 O60499,P20020,Q86Y82,Q7L0J3 4 +Nuclear membrane 0.3608976969576689 1.9670423064474665 0.0491783336216944 1.0 0.2387910530935751 109 Q9BZF1,P50402,Q99720,Q9BVC6,Q8NFH5,Q9Y6K0,Q7Z3B4,Q14739,Q9H1E5,Q9NXE4,Q9H8M7,Q5SNT2,O75844,Q9P035,Q9BTX1,O15504,Q8IWB1,Q96S66,Q96KC8,Q86UE4,Q9UH99,O94901,Q9H2V7,P11802,O14657,Q9UBM7,Q9BW91,P56134,O14681,Q8IXM6,Q8NC56 31 +Compact myelin 0.8933041301627034 1.9220356472794031 0.0546012724527289 1.0 0.2589054922208968 2 Q9NR77 1 +Oxidoreductase complex 0.4088727852601099 1.867512026838912 0.0618301188931069 1.0 0.2821193364569905 63 O43169,Q96CU9,Q9Y375,P21912,O95298,O96000,O75306,Q9Y6M9,Q9P0J0,O14949,Q15118,O95139,P03915,O43676,Q9UDW1,Q9NX14,P03886,Q86Y39 18 +Respiratory chain complex iii 0.7264215394887552 1.834053480069048 0.0666460559181838 1.0 0.2966798844276033 7 O14949,Q9UDW1 2 +Emc complex 0.6775701496219543 1.8325254249456633 0.0668731773493029 1.0 0.2966798844276033 8 Q8N4V1,Q9P0I2,Q9NPA0,Q5J8M3,Q15006 5 +Micos complex 0.8130301103687771 1.8015104027417883 0.071622469150149 1.0 0.3040801727224451 5 Q6UXV4,Q9BUR5,Q5XKP0 3 +Tim23 mitochondrial import inner membrane translocase complex 0.7182842574297809 1.7950836133736447 0.0726403791649255 1.0 0.3065286127923159 7 P12236,P62072,Q99595,O14925 4 +Rough endoplasmic reticulum 0.4556312979172234 1.7912306637981914 0.0732562874184279 1.0 0.3065286127923159 32 Q99442,Q9UGP8,P61619,Q96A33,Q07065,Q9Y5M8,P51571,Q15041,Q5VV42 9 +Phagocytic vesicle membrane 0.5098542660593324 1.7696321536349182 0.076788438868893 1.0 0.3169268295134315 22 P61026,Q93050,Q9Y487,P13473,Q03519,O75396,Q13636,P04439,P11279 9 +Coated vesicle membrane 0.4032584008776773 1.757862516132263 0.0787709050629326 1.0 0.3178843635428569 57 P24390,Q13190,Q9Y3B3,Q8N511,O75340,Q96HR9,Q14108,O15027,P49755,O14653,O75396,Q15363,Q9Y6B6,Q9Y6Y8,P04439,Q3ZAQ7,Q12770,O43731,Q9NR31,P49257 20 +Late endosome membrane 0.4455155888475324 1.751497090405428 0.079860322036471 1.0 0.3184698608506361 33 Q7Z3C6,P51790,O14653,Q9BXS4,Q8IV08,O15118,A4D1P6,Q9UNK0,Q14108,Q15043,P11279 11 +Zymogen granule membrane 0.854818523153941 1.7508035682109937 0.0799797517698945 1.0 0.3184698608506361 2 P49755 1 +Intrinsic component of peroxisomal membrane 0.7528195488721845 1.7283900781012391 0.0839183131268304 1.0 0.3215347006779913 6 O96011,O43808,O14975,Q9Y3D6,P56589 5 +Sarcoplasmic reticulum membrane 0.6185782931600287 1.7263417556633718 0.0842859475035975 1.0 0.3215347006779913 11 Q9BVC6,Q13586,O75298,P16615 4 +Exocytic vesicle 0.423595716023785 1.72189318550289 0.0850888696525364 1.0 0.3215347006779913 39 P50897,P61026,O43760,P51790,Q86Y82,Q9BT78,Q92542,O15400,Q92905,Q9BVK6,O60499,Q6IQ22,Q14141,Q96A57,P20020,P11279,Q7L0J3 17 +Golgi medial cisterna 0.7946430662869735 1.7218696321153042 0.0850931372051779 1.0 0.3215347006779913 5 Q16706,Q9BXS4,O95249 3 +Er ubiquitin ligase complex 0.7498635474110694 1.7149530350163655 0.086353837913937 1.0 0.3240053091977471 6 Q6NTF9,Q9UBU6,Q9UBV2,Q9GZP9 4 +Presynaptic active zone 0.583602224765019 1.7003429600035789 0.0890664341766076 1.0 0.3327602497603025 13 P41440,Q99623,P27824,P20020,Q7L0J3 5 +Proton transporting v type atpase v0 domain 0.8230149376842417 1.6948088519329427 0.0901116877187644 1.0 0.3327602497603025 4 Q93050 1 +Vacuolar proton transporting v type atpase v0 domain 0.8230149376842417 1.6948088519329427 0.0901116877187644 1.0 0.3327602497603025 4 Q93050 1 +Rough endoplasmic reticulum membrane 0.5644231353673341 1.6795506884431617 0.0930447688228144 1.0 0.3406639116577237 14 P61619,Q96A33,Q9Y5M8,P51571,Q15041 5 +Autophagosome 0.4542327124418898 1.6738226437750272 0.0941654607237245 1.0 0.3433824832816943 30 Q7Z3C6,Q969Q5,Q9Y371,P13473,Q6IQ22,Q9Y6I9,Q96A57,P11279,Q9UMX0 9 +Platelet alpha granule membrane 0.8357321652065264 1.6653120145735596 0.0958505227686183 1.0 0.347388658821976 2 Q96JJ7 1 +Postsynaptic cytoskeleton 0.8351063829787224 1.6625036584757733 0.0964118304219576 1.0 0.347388658821976 2 P07196 1 +Paranodal junction 0.8351063829787218 1.662503658475771 0.0964118304219581 1.0 0.347388658821976 2 Q8IXJ6 1 +Postsynaptic density membrane 0.6861676186799405 1.6398561311903532 0.101035083995421 1.0 0.3555808382474508 7 P57105 1 +Apical plasma membrane 0.4060300187340086 1.6266140224040524 0.1038190992837595 1.0 0.3625682390371295 43 P41440,P08183,P51790,P05023,Q9Y6M7,O15020,P17302,P36551,Q15043,Q86UE4,P20020,Q8TAD4,Q16181,P30825 14 +Trans golgi network membrane 0.4909858196220557 1.595949247288545 0.1105001250633046 1.0 0.3771959156296264 21 Q9NX62,O60499,Q8N2H4 3 +Parallel fiber to purkinje cell synapse 0.8188360450563189 1.5893846408938066 0.111973580028938 1.0 0.3793731741278947 2 O15020 1 +Signal peptidase complex 0.8935050588819073 1.5830055296403742 0.1134202040482015 1.0 0.3804534370285317 3 P67812 1 +Anaphase promoting complex 0.6165008855018052 1.5780580131946038 0.1145522828130105 1.0 0.3804534370285317 9 Q96DE5,Q9UJX5,Q12834,Q9UJX2,P30260,O60566 6 +Integral component of synaptic vesicle membrane 0.7616661446914958 1.577786146417952 0.1146147475232783 1.0 0.3804534370285317 5 O60499,P20020,Q86Y82,Q7L0J3 4 +Cytoplasmic ubiquitin ligase complex 0.6145186955722495 1.56744113722773 0.1170116147978848 1.0 0.3821818209945302 9 Q6NTF9,Q9UBU6,Q9UBV2,Q9GZP9 4 +Respiratory chain complex iv 0.6140928495416889 1.5651589616047454 0.1175456413324465 1.0 0.3825499725084638 9 O00483,P00403,P13073,P20674,O14548 5 +Copi coated vesicle 0.5449507499007067 1.558457918356856 0.1191247361166889 1.0 0.3849297522916496 14 P49755,P24390,Q8N511,Q9Y3B3 4 +Platelet dense granule lumen 0.8088235294117888 1.5443049767931605 0.1225144674895144 1.0 0.3903267946683478 2 Q92520 1 +Endosome membrane 0.3323843146882286 1.5301880678168038 0.1259701840298006 1.0 0.3971559968717326 118 O60831,Q9BRG1,Q9Y487,Q9BXS4,Q15904,Q9UNK0,Q6IQ22,Q86YV9,Q13546,Q8N4V1,P51790,P13473,Q9BXB4,Q8IV08,O15118,Q14108,P11279,O14653,Q658P3,Q92543,O00461,Q15043,Q9UH99,P10321,O14828,O15400,P04439,Q86Y82,P42892,Q93050,Q7Z3C6,P61026,O14964,Q92542,A4D1P6,Q13636,Q9Y287 37 +Chloride channel complex 0.705010697498058 1.509255484498994 0.1312335059557043 1.0 0.4039322827382358 6 Q4KMQ2,Q96S66,Q9C0H2 3 +Gaba ergic synapse 0.5901776518129978 1.4991587007529497 0.1338324661870764 1.0 0.4091578427537556 10 P41440,Q99623,P20020,Q7L0J3 4 +Hrd1p ubiquitin ligase erad l complex 0.741201091033423 1.487657017201676 0.1368413685005558 1.0 0.4103122846242149 5 Q6NTF9,Q9UBV2,Q9GZP9 3 +Intrinsic component of mitochondrial outer membrane 0.5319218453719695 1.4766801767684037 0.1397613883648469 1.0 0.4120238332314319 14 O96008,Q969V5,P57105,Q8TB36,Q9BWH2,Q8IWA4 6 +Golgi associated vesicle membrane 0.4803955544982312 1.4628899581923849 0.1434974921906289 1.0 0.4189573083893603 19 Q8N511,P24390,Q15363,P17302,Q9Y3B3,Q9Y287,Q9HD26 7 +Gpi anchor transamidase complex 0.726468321603049 1.4224891795776329 0.1548842904952669 1.0 0.4344925164732244 5 Q92643,O43292,Q9H490 3 +Golgi lumen 0.7262827048774062 1.4216667998521757 0.1551230025451238 1.0 0.4344925164732244 5 O00461,Q9NX62 2 +Copii vesicle coat 0.5498653862385736 1.4133811163538017 0.1575436948957458 1.0 0.4361270578211501 12 Q9NR31,O95486,O75340,P55735,Q9Y6B6,Q9Y3B3 6 +Nuclear pore central transport channel 0.7553123817604983 1.407909455108305 0.1591578829745474 1.0 0.437352500862404 4 Q7Z3B4 1 +Histone pre mrna 3 end processing complex 0.7765957446808479 1.398956410816144 0.1618260547402281 1.0 0.437352500862404 2 O60506 1 +Proteasome core complex beta subunit complex 0.6364986978188081 1.3957832150391765 0.1627797863883271 1.0 0.437352500862404 7 P28074,P49721 2 +Protein lipid complex 0.7156633747146703 1.374568286472476 0.1692653262148842 1.0 0.44135388994546 5 Q9BUR5 1 +Gamma secretase complex 0.766583229036313 1.353781944185639 0.1758059557789841 1.0 0.4512845748680148 2 P49755 1 +Dynactin complex 0.7422185394821734 1.3519865742250496 0.1763796102426207 1.0 0.4512845748680148 4 O75935,Q13561 2 +Sec61 translocon complex 0.7392742879366476 1.339400096057758 0.1804404581665839 1.0 0.4525899421504606 4 Q15041,P51571 2 +Translocon complex 0.7392742879366476 1.339400096057758 0.1804404581665839 1.0 0.4525899421504606 4 Q15041,P51571 2 +Nuclear outer membrane 0.5444389234708451 1.3054541450608024 0.1917382516025274 1.0 0.4678490299845245 11 Q8IWB1,Q9UBM7,P50402,Q99720,Q9BVC6 5 +Atpase dependent transmembrane transport complex 0.6999576354302097 1.3047584551053064 0.191975109773935 1.0 0.4678490299845245 5 Q9NUT2,O14678,P05023 3 +Mitochondrial permeability transition pore complex 0.7311544101650779 1.304670961825989 0.1920049134097996 1.0 0.4678490299845245 4 P21796,P12235 2 +Copi coated vesicle membrane 0.5179634646145435 1.3020622506657955 0.1928951062915866 1.0 0.4678490299845245 13 Q9Y3B3,P24390,Q8N511,Q15363 4 +Golgi trans cisterna 0.8229336653885391 1.2979373286733176 0.1943088715180525 1.0 0.4678490299845245 3 Q9BXS4 1 +Autophagosome membrane 0.5171459659207545 1.2970232212152188 0.1946231970807941 1.0 0.4678490299845245 13 Q7Z3C6,Q9Y371,P11279,Q9Y6I9 4 +Endoplasmic reticulum plasma membrane contact site 0.8208140286382887 1.289363884963005 0.1972716107273453 1.0 0.4678490299845245 3 Q96BY9 1 +Mitochondrial intermembrane space protein transporter complex 0.7257357545397575 1.2814841714766183 0.2000236561145705 1.0 0.4698158857962735 4 Q9Y5J6,P62072,Q9Y5J9 3 +Neuronal dense core vesicle 0.7478097622027491 1.2691618306800017 0.2043833514245032 1.0 0.4770696223481978 2 Q96RL7 1 +Golgi associated vesicle 0.4077989517698894 1.26504408244137 0.2058555259750922 1.0 0.4780481268168383 30 P49755,Q8N511,P24390,Q9BVK6,Q15363,P17302,Q9Y3B3,Q9Y287,Q9HD26 9 +Tim22 mitochondrial import inner membrane insertion complex 0.8103286384976497 1.2469682066776075 0.2124091554262661 1.0 0.48497974757618 3 Q53H12,P62072 2 +Platelet dense granule 0.8090766823160951 1.24190841181164 0.214270356135382 1.0 0.4863937084273172 3 Q92520,P13473 2 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.6462025725114875 1.2354626972803129 0.2166583511720672 1.0 0.4869450070896956 6 P24539,O75964 2 +Haus complex 0.6833698715940918 1.230890540604736 0.2183638059856705 1.0 0.4882851727153777 5 Q68CZ6,O94927,Q7Z4H7,Q9H6D7 4 +External side of plasma membrane 0.4308485597691458 1.2281100140657066 0.2194056723214472 1.0 0.4882851727153777 24 P41440,P42892,P08183,P51790,O96005,P11279 6 +Nuclear cyclin dependent protein kinase holoenzyme complex 0.7123442626782476 1.2241623962582728 0.2208909716020106 1.0 0.488957815767096 4 P50750,Q9P287 2 +Atp binding cassette abc transporter complex 0.7371714643304246 1.221303744888922 0.2219710360348883 1.0 0.488957815767096 2 O14678 1 +Oligosaccharyltransferase complex 0.5589182283778341 1.21156537394383 0.2256787958610953 1.0 0.4933810366822377 8 Q8TCJ2,P46977 2 +Dendrite membrane 0.7064778982730744 1.1990516166949878 0.2305078756812348 1.0 0.4961607161529855 4 P20020 1 +Cell body membrane 0.7969834113833384 1.193068977587476 0.2328423598761824 1.0 0.4980952581893801 3 P20020 1 +Specific granule membrane 0.4736511565823275 1.1909126869924496 0.2336878634236519 1.0 0.4980952581893801 15 O00264,P30519,Q08722,Q07065 4 +Proton transporting v type atpase complex 0.522448133173123 1.1781208575323352 0.238748427968888 1.0 0.5053230130437071 11 Q93050,Q8N511 2 +Cortical endoplasmic reticulum 0.7921752738654165 1.173673405766514 0.2405258663675777 1.0 0.5067227068718344 3 Q13586,P50402 2 +Ion channel complex 0.4389687507452198 1.1596788058448244 0.2461796023454583 1.0 0.5126859608478811 19 Q96S66,Q9BPX6,Q8N2K0,Q4KMQ2,Q9C0H2 5 +Dense core granule membrane 0.7224655819774667 1.1553269012118097 0.2479565837480399 1.0 0.513983226399386 2 Q12756 1 +Secretory vesicle 0.2956909033162893 1.1513548014692967 0.2495863003926017 1.0 0.513983226399386 259 Q969Q5,P14174,Q8NBM8,O95298,Q9Y487,Q5T9A4,Q9UHQ9,Q07065,Q8NF37,P45880,O60499,Q99536,Q6IQ22,Q9BVK6,Q9H7Z7,Q08722,Q4KMQ2,Q9BTY2,Q7L0J3,P50897,Q9NQX7,O43760,P51790,Q6UXV4,P13473,Q96CS3,P30519,Q8NBX0,Q9Y6I9,Q92520,Q96A57,P17900,P20020,P11279,P49755,P15586,Q8WVQ1,P35613,O43681,Q15363,Q9NZJ7,O00487,O15400,Q8TAD4,O00264,P42892,Q93050,P61026,Q08380,O14975,Q9H0U3,P10619,Q92905,P15291,Q96JJ7,P42785,P07602,P08236,Q13510,Q13636,O15260,P09960 62 +Acrosomal membrane 0.7168335419274346 1.1301309664196282 0.2584210430987406 1.0 0.5240931232912981 2 P35613 1 +Postsynaptic specialization membrane 0.5104222811015298 1.108183411161883 0.2677826135905969 1.0 0.5331127702628291 11 P57105 1 +Cytoplasmic microtubule 0.4278165915276394 1.0971204868518951 0.2725887256470762 1.0 0.5352760579941677 20 Q9Y5M8,Q6NUK4,Q9BRK0 3 +Endocytic vesicle membrane 0.3635470631626025 1.092167447479015 0.2747595078080365 1.0 0.5376759333829679 37 P61026,Q93050,Q9Y487,P13473,Q03519,O75396,Q14108,Q8WTV0,Q13636,P04439,P11279 11 +Microtubule organizing center attachment site 0.7660433517072852 1.06859696512343 0.2852513166630741 1.0 0.5489432084833072 3 O94901 1 +Sperm annulus 0.7626688166732853 1.0550818012145329 0.2913879144821931 1.0 0.5556039926034485 3 Q16181 1 +Presynapse 0.3183642572092968 1.039064970489088 0.2987745209929369 1.0 0.5605108782264188 89 P07196,P14672,O15020,Q9BVK6,O60499,Q6IQ22,Q9BTU6,Q7L0J3,P50897,P41440,O43760,P51790,Q14141,Q96A57,P20020,P11279,P23634,Q9UQB8,Q99623,Q13641,O15400,Q86Y82,P61026,Q9BT78,Q92905,Q92542,P27824,O76024,Q00535 29 +Ccr4 not core complex 0.7576660573073986 1.0350738020524557 0.3006344461909571 1.0 0.560525825752339 3 Q92600 1 +Ccr4 not complex 0.7576660573073986 1.0350738020524557 0.3006344461909571 1.0 0.560525825752339 3 Q92600 1 +Recycling endosome 0.3549531672396646 1.0292609190808937 0.3033570825637892 1.0 0.5621392468733074 39 Q7Z3C6,P61026,O14773,P51790,O15400,Q9UNK0,Q6IQ22,O14828,Q96A57,O14966 10 +Phagocytic vesicle 0.3546697739874321 1.02633763795038 0.3047324620035401 1.0 0.5623924298764521 39 P61026,Q93050,O14964,P61106,P51790,Q86Y82,Q9Y487,P13473,Q03519,O75396,Q9UNK0,P08670,Q13636,P10321,P04439,P11279 16 +Endoplasmic reticulum lumen 0.3378143692742122 1.0166906518000252 0.3093006142122523 1.0 0.5669794567264591 61 Q9BV10,Q07065,Q9BTY2,Q6P179,Q9NZ08,O75718,O43852,Q9NWM8,O43681,Q14257,O15460,Q02818,Q32P28,O14657,Q96HE7,O14975,Q8NBJ7,P27824,Q9Y680,Q8TED1,Q5JRA6,P53634,Q9NWW5 23 +Insulin responsive compartment 0.6336903029924817 1.0097039700719987 0.3126371398336576 1.0 0.570398534728731 5 P61026,Q6IQ22,P14672 3 +Endoplasmic reticulum tubular network membrane 0.6604544351206633 1.0026005658939685 0.316053622668234 1.0 0.5728077632390348 4 Q9NQC3 1 +Carboxy terminal domain protein kinase complex 0.5530194752259139 0.9788887639329742 0.3276349445422366 1.0 0.5869550444658173 7 P50750,P32780,O75909 3 +Mitochondrial crista 0.7435361177816149 0.9787708975526882 0.3276931923432533 1.0 0.5869550444658173 3 Q9BUB7 1 +Early endosome 0.3062988228098318 0.9443986868893351 0.3449659522495112 1.0 0.6069234413867757 94 Q92544,Q9UIQ6,Q9UNK0,Q86YV9,P41440,Q8N4V1,P51790,Q8IV08,Q96A57,O14966,Q5VW38,Q92543,P62820,Q9GZP9,Q15043,P10321,O15400,P04439,Q86Y82,P31751,O14964,Q14699,A4D1P6,Q13510,Q13636,Q9NWW5 26 +Autolysosome 0.7333731710989453 0.938497951848752 0.3479885690297128 1.0 0.6076415782288063 3 P11279 1 +Secondary lysosome 0.7333731710989453 0.938497951848752 0.3479885690297128 1.0 0.6076415782288063 3 P11279 1 +Nuclear pore outer ring 0.5053291536050263 0.9242660568156802 0.3553478106358456 1.0 0.6132829729886641 8 Q8NFH4,P57740,Q8WUM0,Q12769,Q9BW27,P55735,Q8NFH3 7 +Intrinsic component of synaptic membrane 0.4878133151181184 0.9232619774871432 0.3558706974222909 1.0 0.6132829729886641 10 P27824,P20020,P23634,P51790 4 +Sarcoplasm 0.400716086453906 0.911980561914868 0.3617789501710655 1.0 0.6199651117300774 21 Q13586,O43852,Q9BVC6,P52789,O75298,P16615 6 +Paraspeckles 0.5770460877167808 0.9118001928697352 0.3618739088292302 1.0 0.6199651117300774 6 Q8WXF1,P23246,P52272,Q15233 4 +Platelet alpha granule 0.4191302578576923 0.9076852295648218 0.3640445498867328 1.0 0.6213391941675817 16 Q8NBM8,Q6UXV4,Q96JJ7,Q8NBX0,Q9Y6I9 5 +Dense core granule 0.7226917057903018 0.8964090521276454 0.3700343344598984 1.0 0.6291969582202018 3 Q96RL7,Q12756 2 +Torc1 complex 0.6589486858573155 0.8750907714577881 0.3815245180088218 1.0 0.6331460996593282 2 P42345 1 +Tor complex 0.6589486858573155 0.8750907714577881 0.3815245180088218 1.0 0.6331460996593282 2 P42345 1 +Secretory granule 0.2827829035514714 0.8700978179259953 0.3842469500749905 1.0 0.635512259869019 232 Q969Q5,P14174,Q8NBM8,O95298,Q9Y487,Q5T9A4,Q9UHQ9,Q07065,Q8NF37,P45880,Q99536,Q6IQ22,Q9H7Z7,Q08722,Q4KMQ2,Q9BTY2,Q9NQX7,P51790,Q6UXV4,P13473,Q96CS3,P30519,Q8NBX0,Q9Y6I9,Q92520,P17900,P11279,P49755,P15586,Q8WVQ1,P35613,O43681,Q15363,Q9NZJ7,O00487,O15400,Q8TAD4,O00264,P42892,Q93050,P61026,Q08380,O14975,Q9H0U3,P10619,P15291,Q96JJ7,P42785,P07602,P08236,Q13510,Q13636,O15260,P09960 54 +Lumenal side of membrane 0.4778139616828851 0.8666958308272126 0.3861086903987569 1.0 0.636281012654931 10 P10619,P27824,P51572,P10321,P04439 5 +Intrinsic component of vacuolar membrane 0.7151059214572888 0.8666874973021068 0.3861132576793689 1.0 0.636281012654931 3 O15118 1 +Basolateral plasma membrane 0.3347084199287446 0.8578811822497665 0.3909580760712563 1.0 0.6377019977659801 42 P41440,P15291,P05023,P35613,Q9Y6M7,P57105,Q15043,P20020,P30825 9 +Perinuclear endoplasmic reticulum 0.5986189565537308 0.8549224679318962 0.3925940713118754 1.0 0.6377019977659801 5 O60858 1 +Intraciliary transport particle 0.6250042020602187 0.8530679309005345 0.3936216341217786 1.0 0.6382293638974553 4 Q7Z4L5 1 +Synaptic vesicle membrane 0.4453452102770668 0.8506845879689989 0.3949445867749068 1.0 0.6385351931542856 13 O43760,O60499,P20020,Q86Y82,Q7L0J3 5 +Dendritic spine membrane 0.7105963743636494 0.8490923064380278 0.3958299310878395 1.0 0.6385351931542856 3 P20020 1 +Postsynaptic membrane 0.3565879085884392 0.8431058745272251 0.3991692335715517 1.0 0.6385351931542856 31 Q8NBU5,P51790,Q99720,P27824,P57105,Q8NCG7 6 +Apical part of cell 0.3222208249219816 0.8162410459266014 0.4143622852114987 1.0 0.6509359082561261 53 P41440,P08183,P51790,P05023,Q9Y6M7,O15020,P17302,P36551,Q15043,Q86UE4,P20020,Q8TAD4,Q16181,P30825 14 +Pigment granule 0.3212507861439034 0.8107042748811145 0.417535517817218 1.0 0.6537118262382472 59 P41440,P49755,Q93050,P57088,O14773,O43852,P62820,P27824,P05023,P35613,P61019,P11279,O14966 13 +Ciliary tip 0.5126364512423187 0.7780522322806911 0.4365382214568742 1.0 0.6712431329934336 7 Q7Z4L5 1 +External encapsulating structure 0.3382413035818251 0.7774396280357425 0.4368994400871357 1.0 0.6712431329934336 34 Q96JX3,P07602,Q53GQ0,Q9NZJ7,P84157,Q32P28 6 +Neuromuscular junction 0.3880391681598124 0.7736992820371861 0.4391086446963208 1.0 0.6734977185544921 17 P07196,P57105,O43760,Q7L0J3 4 +Caspase complex 0.5463276334588861 0.7697690701513398 0.4414368900276475 1.0 0.6759269749495851 6 O43292,Q9H490 2 +Messenger ribonucleoprotein complex 0.603258949509084 0.7628319756330859 0.4455636087935279 1.0 0.6779915541355731 4 P51991,Q99729 2 +Cop9 signalosome 0.458744264313817 0.7592768193309744 0.4476869811455912 1.0 0.6779915541355731 10 Q7L5N1,Q92905,Q9UNS2 3 +Derlin 1 retrotranslocation complex 0.5761965290679154 0.7573641441200899 0.4488317314084022 1.0 0.6780093532174298 5 Q9UBV2 1 +Early endosome membrane 0.3257030145632861 0.7491528063682298 0.4537651102597466 1.0 0.6832814595619402 41 P51790,Q8N4V1,Q86Y82,Q8IV08,Q92543,A4D1P6,Q15043,P10321,Q13636,O15400,P04439,Q86YV9 12 +Zymogen granule 0.6839968941610954 0.7466144436293964 0.4552963272733765 1.0 0.6833207688664891 3 P49755 1 +Synaptic membrane 0.3240395992346809 0.7200721654428488 0.4714805642677695 1.0 0.6895788635634139 40 Q8NBU5,Q9UQB8,P23634,P51790,Q99720,P27824,P57105,Q8NCG7,P20020,Q9BTU6,Q9BPW8 11 +Organelle envelope lumen 0.3250457717788223 0.7199205006251079 0.4715739449248914 1.0 0.6895788635634139 39 Q9Y5J6,Q9Y3B1,O14925,O60313,Q9BPX6,P62072,Q96BR5,P36551,Q9H4A6,Q16891,Q53H12,P51970,Q9NR28 13 +Side of membrane 0.306430037262637 0.7142335430631699 0.4750827785126978 1.0 0.6921711163667822 75 P14672,Q9UBI6,O96005,P41440,Q9NV70,P08183,P51790,P51572,P17900,P20020,P11279,P63218,P10321,Q9H1P3,P04439,P42892,P10619,P27824,P15291,Q96DA6,Q08209,Q9NR28 22 +Sodium potassium exchanging atpase complex 0.6748671116452709 0.7120410287959736 0.4764393697458577 1.0 0.6921711163667822 3 P05023 1 +Cation transporting atpase complex 0.6748671116452709 0.7120410287959736 0.4764393697458577 1.0 0.6921711163667822 3 P05023 1 +Anchored component of synaptic vesicle membrane 0.5889167188478325 0.7041955680936081 0.481310990651139 1.0 0.6981315966633135 4 P20339,P20337,P51149 3 +Endoplasmic reticulum quality control compartment 0.4964572275550363 0.6986849681220874 0.484748930066496 1.0 0.7019968556624855 7 Q9UKV5,O60858 2 +Cyclin cdk positive transcription elongation factor complex 0.6668014861683653 0.6817949103210978 0.4953686430579369 1.0 0.7162336431474629 3 P50750 1 +Excitatory synapse 0.5248619758907583 0.6721482813136617 0.5014893022682729 1.0 0.7207486464206337 6 O15020,P23634 2 +Eukaryotic translation initiation factor 2b complex 0.5528201970427512 0.6574829774870851 0.5108704128624466 1.0 0.731656679620034 5 P49770,Q13144 2 +Intrinsic component of postsynaptic membrane 0.5192659814462545 0.6470036114948188 0.5176296061095336 1.0 0.7378456551765409 6 P27824,P51790 2 +Uniplex complex 0.6563380281689928 0.6430129589717297 0.52021569117134 1.0 0.738006037248702 3 Q8IYU8,Q9BPX6 2 +Caveola 0.3983979270665958 0.6208699246047001 0.5346852109805329 1.0 0.7492194005714875 14 P09601,Q8WTV0 2 +T tubule 0.4382472885847447 0.605610300035924 0.5447735610464735 1.0 0.7587376254658408 9 O75298,P05023 2 +Intrinsic component of presynaptic membrane 0.529907910587012 0.5620794786686727 0.5740618693800621 1.0 0.787383953772049 5 P27824,P20020,P23634 3 +Neuron projection terminus 0.3754646070893804 0.5371356320652947 0.5911739294796305 1.0 0.8069248229451224 15 Q13641,Q14141,P51790 3 +Integral component of presynaptic active zone membrane 0.5457344523770354 0.5335676011256913 0.5936407287746055 1.0 0.8069248229451224 4 P27824,P20020 2 +Intrinsic component of presynaptic active zone membrane 0.5457344523770354 0.5335676011256913 0.5936407287746055 1.0 0.8069248229451224 4 P27824,P20020 2 +Presynaptic active zone membrane 0.5457344523770354 0.5335676011256913 0.5936407287746055 1.0 0.8069248229451224 4 P27824,P20020 2 +Nucleoid 0.3082273784925898 0.5318447686759115 0.5948335130823543 1.0 0.807337563346454 37 O00411,Q12849,P05141,P49748,Q9BRT2,P45880,P51530,P21796,Q9NVI7,P40939,Q96AG4 11 +Cell surface 0.2878676279707989 0.5240218064003879 0.6002633729171949 1.0 0.8122789010563531 82 P42892,P41440,P14174,P08183,P51790,P11279,Q99623,P15291,Q96JJ7,Q13641,Q08722,O96005,O15258,Q4KMQ2,Q8WTV0,O75298 16 +Sin3 complex 0.5151894769809096 0.5024636820724668 0.6153413931695242 1.0 0.8253027843396278 5 Q9UBU8,P68400,Q13547,Q92769 4 +Cis golgi network membrane 0.614162432994066 0.4930160219025609 0.6220012665957524 1.0 0.8274984921185754 3 Q9NPR9 1 +Phagophore assembly site 0.4530135069157274 0.4916610391435627 0.6229589851827821 1.0 0.8274984921185754 7 Q7Z3C6,Q5MNZ6,Q13501,Q86Y82,Q9H0U4 5 +Clathrin coated vesicle 0.2991231726267721 0.4911860435175549 0.6232948691240245 1.0 0.8274984921185754 43 P49755,P42892,Q5VW38,P51572,Q9BVK6,Q14108 6 +Brush border membrane 0.413202297802056 0.474137929747939 0.6354015523180769 1.0 0.8393954178309784 9 P41440,P40855 2 +Mhc protein complex 0.5972557933451974 0.4363467198886537 0.6625851895109509 1.0 0.8559958254804934 3 P04439 1 +Mhc class i protein complex 0.5972557933451974 0.4363467198886537 0.6625851895109509 1.0 0.8559958254804934 3 P04439 1 +Cyclin dependent protein kinase holoenzyme complex 0.3763712615609726 0.4308297213887433 0.6665921870095999 1.0 0.8585329160350591 13 P11802,P50750,Q00535,Q9P287 4 +Photoreceptor inner segment 0.4377231575570237 0.4219055262835773 0.6730939761812051 1.0 0.8645025127895449 7 Q96HR9,P35613 2 +Perinuclear region of cytoplasm 0.2558151665384425 0.421094498055197 0.6736860790324937 1.0 0.8645025127895449 180 Q9UNS2,Q9UIQ6,Q9Y487,Q8N4A0,O60858,Q07065,O60499,Q9H7Z7,O75503,Q9NQX7,P09601,P51572,O75935,O15118,O75340,P11279,O14966,Q9H0U4,Q8IZ07,Q7L5N1,Q9UBB4,Q9UKV5,Q86UE4,Q8IXJ6,Q9UMX0,P42892,Q93050,P61026,Q6NTF9,Q01105,Q10472 31 +Smn complex 0.4657076671015315 0.4158025423608051 0.6775544983433834 1.0 0.866481450594028 6 Q16637,Q9NWZ8 2 +Dendrite cytoplasm 0.3950195786049939 0.4119687526542906 0.680362326450092 1.0 0.867653079236915 10 Q8N2K0,P27824,P23246,Q9UQB8 4 +Bleb 0.4882046370121018 0.3974552536523104 0.6910317771954217 1.0 0.8771171490415292 5 Q96RD7 1 +Lewy body 0.5372340425531792 0.3953109332737525 0.6926134315669343 1.0 0.8771171490415292 2 Q13501 1 +Basal part of cell 0.2835843575060599 0.3791991706970536 0.7045399673541439 1.0 0.8860419534038265 50 P41440,P23634,P15291,P05023,P35613,Q9Y6M7,P57105,Q15043,P20020,P30825 10 +Anchored component of synaptic membrane 0.5265957446808391 0.3598886768581794 0.7189303850387416 1.0 0.8942608213028859 2 Q9NQX3 1 +Gemini of coiled bodies 0.4495508094469851 0.3506230984078021 0.7258711253405816 1.0 0.8967224242302695 6 Q16637,Q9NWZ8 2 +Lumenal side of endoplasmic reticulum membrane 0.4191297802742892 0.3401203438337634 0.7337659019310241 1.0 0.9040155209679374 7 P51572,P27824,P04439 3 +Transcription factor tfiih holo complex 0.4912843156555058 0.3373156221401647 0.7358789843367604 1.0 0.9053904034929248 4 P32780 1 +Beta catenin destruction complex 0.4694644534920296 0.3285022187929878 0.7425319669358257 1.0 0.9093518135881076 5 P49840,Q9HB71,P35222,P49841 4 +Sarcolemma 0.3057915742071884 0.3236076754382074 0.7462350762597065 1.0 0.9093518135881076 29 P41440,Q9NXE4,P23634,Q92542,P05023,P35613,O75298,Q08209,P11279,Q96QD8 10 +Mitotic spindle microtubule 0.4149503452323538 0.3222678254280515 0.7472498055420416 1.0 0.9093518135881076 7 Q68CZ6,Q9H6D7 2 +Peptidase complex 0.2781621436151705 0.3009467925988153 0.7634550679630139 1.0 0.9190359637373724 65 P67812,Q9H490,O43292,P49721,O43396,P28074,Q92643,O00487,Q9UMX0,Q15005 10 +Platelet alpha granule lumen 0.362097990120991 0.2729426466469159 0.7848973033820497 1.0 0.9316166685894132 11 Q6UXV4,Q8NBM8,Q8NBX0 3 +Phagophore assembly site membrane 0.4456805198011079 0.246693947612946 0.805145090935026 1.0 0.946342491399237 5 Q7Z3C6 1 +H3 histone acetyltransferase complex 0.4887359198998621 0.2461754308950063 0.8055464337165157 1.0 0.946342491399237 2 Q8WYH8 1 +Azurophil granule lumen 0.2785242423341798 0.2415291762606537 0.8091450063223049 1.0 0.946783074408058 37 P15586,Q96CS3,P10619,O43681,P08236,Q99536,Q9H7Z7,P17900,Q9BTY2 9 +Septin cytoskeleton 0.4434738513028119 0.2394648173235025 0.8107451746259391 1.0 0.9474345155216892 5 Q16181 1 +Mmxd complex 0.529478155121178 0.2359455855933072 0.8134748944800596 1.0 0.9480531457419712 3 P05141 1 +Growth cone membrane 0.4821652065081283 0.2285802561611477 0.8191951716189976 1.0 0.9487617548852676 2 Q9UPT5 1 +Tubular endosome 0.4546023794614923 0.2223797200640238 0.8240182976400483 1.0 0.9519193565612772 4 Q96QK1,O75436,Q9UNH7 3 +Prefoldin complex 0.5179968701095551 0.2070534360049751 0.8359681267005423 1.0 0.9600537551646822 3 Q9UHV9,Q99471 2 +Plasma membrane signaling receptor complex 0.3608604336971555 0.2015825149949461 0.8402431156256833 1.0 0.9617526837976942 8 Q8N2K0 1 +Tertiary granule 0.2723241412020056 0.200609410909822 0.8410039988274991 1.0 0.9617526837976942 41 Q93050,P13473,Q8WVQ1,Q5T9A4,P27105,P42785,Q08722,Q13510,O15400,Q4KMQ2,P11279,P09960 12 +Collagen containing extracellular matrix 0.2825288315875551 0.155535166815202 0.8763994321528503 1.0 0.9836473231085144 30 P84157,Q9NZJ7,P07602 3 +Ficolin 1 rich granule membrane 0.2980630361575664 0.1470549744681118 0.8830886285862083 1.0 0.9887108196748176 18 Q93050,P13473,Q5T9A4,P42785,P11279 5 +Blood microparticle 0.2954265229122464 0.1415827244582766 0.887409613340524 1.0 0.991104463607867 17 P04062 1 +Endocytic vesicle 0.2622871945730565 0.1329922150868193 0.8941995372700311 1.0 0.9962370304799856 74 Q969Q5,Q9Y487,Q9UNK0,P08670,P51790,P13473,Q14108,P11279,Q03519,O75396,O00461,P10321,O15400,P04439,Q86Y82,P61026,Q93050,Q13636,Q8WTV0 19 +Membrane microdomain 0.2636910144815189 0.1309463494998028 0.8958177487265133 1.0 0.9968168086319537 67 P41440,P50897,Q13586,P23634,O14773,P09601,P13473,P27105,P05141,P05023,P35613,Q9NWW5,O15118,P17302,P21796,Q8WTV0,P20020,Q9BTU6 18 +Schaffer collateral ca1 synapse 0.314222385603438 0.1269201029053039 0.8990036354951565 1.0 0.99913745536059 14 Q16352,P07196,Q9UQB8,Q00535 4 +Perinucleolar compartment 0.4757433489827948 0.1153776289249365 0.908145810063598 1.0 1.0 3 P58107,Q92879 2 +Tight junction 0.2866885560888402 0.1099515274275789 0.9124478172545016 1.0 1.0 25 P11802,Q86UE4,Q9NR77 3 +Endopeptidase complex 0.2596009684887368 0.0956221921255632 0.9238206391955216 1.0 1.0 56 Q9H490,O43292,P49721,O43396,P28074,Q92643,O00487,Q9UMX0 8 +Specific granule 0.2672001792770453 0.0897562045511621 0.9284809513624256 1.0 1.0 33 O00264,P30519,Q08722,Q07065 4 +Neuron projection membrane 0.3306635705550046 0.0819538919331954 0.9346833789644592 1.0 1.0 8 P20020 1 +Nata complex 0.4566510172144075 0.0818388670919911 0.9347748482513764 1.0 1.0 3 P41227,Q9GZZ1 2 +N terminal protein acetyltransferase complex 0.4566510172144075 0.0818388670919911 0.9347748482513764 1.0 1.0 3 P41227,Q9GZZ1 2 +Ap 3 adaptor complex 0.4553990610328732 0.0798129656542652 0.936386012122296 1.0 1.0 3 O14617,Q92572 2 +Ubiquitin conjugating enzyme complex 0.4547730829421057 0.0788079837278215 0.9371853537044827 1.0 1.0 3 P61088,O75150 2 +Cd40 receptor complex 0.3963681903569192 0.0780918640950681 0.9377549789432176 1.0 1.0 4 O43464,O15111,Q9NR28 3 +Manchette 0.4522691705790392 0.0748411022457387 0.9403411386382888 1.0 1.0 3 P62826,Q96SI9 2 +Hippocampal mossy fiber to ca3 synapse 0.3913587977457698 0.0681339827113551 0.9456789789089604 1.0 1.0 4 P47756,O60716,Q15375 3 +Nucleotide excision repair complex 0.3785685138460417 0.0595160350872822 0.9525410939635504 1.0 1.0 5 P18887 1 +Tertiary granule membrane 0.3109560081938012 0.0587013908007779 0.953189951551462 1.0 1.0 12 Q4KMQ2,Q08722,P27105,P10253 4 +Esc e z complex 0.4190923317683988 0.030125547566346 0.9759669259632332 1.0 1.0 3 Q92769,Q15022 2 +Proteasome core complex 0.2880419222222873 0.0270103278627699 0.9784514965944222 1.0 1.0 15 P28074,P28072,P49721 3 +Pericentriolar material 0.3548185231539338 0.0233940871148813 0.9813359215155996 1.0 1.0 2 Q15154 1 +Trans golgi network transport vesicle 0.2986858407314974 0.0080683954549828 0.9935624216827504 1.0 1.0 12 P49755,Q9BVK6,P14672,Q9HD26 4 +Elongator holoenzyme complex 0.3943661971831061 0.0057377736448189 0.9954219441152592 1.0 1.0 3 Q9H9T3,Q6IA86 2 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e173bf4f19bc1afd2e1e64350ea3dcf6b3af538d --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Axonemal microtubule", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Cbm complex", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Connexin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna recombinase mediator complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystroglycan complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle a", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of the cytoplasmic side of the plasma membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mks complex", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Serine type endopeptidase complex", "Serine type peptidase complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG5", "ALKBH5", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC10", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG9A", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP8", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCCIP", "BCKDHB", "BCL2L13", "BCLAF1", "BCS1L", "BEND3", "BET1", "BIRC6", "BLOC1S1", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf57", "C12orf73", "C14orf2", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CASP2", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC86", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPI", "CENPK", "CENPU", "CENPV", "CEP170", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT2", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG8", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC27", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNTTIP2", "DOCK7", "DOLK", "DOLPP1", "DPAGT1", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DRG1", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP3", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO21", "FBXO22", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GIPC1", "GJA1", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH1", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HP1BP3", "HPF1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFT27", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ISG20L2", "ISOC1", "IST1", "ISY1", "ITGB1", "ITM2B", "ITM2C", "ITPRIP", "IVD", "JAGN1", "JAK1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "MACF1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MALT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED14", "MED16", "MED18", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METTL1", "METTL3", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MGAT2", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFMT", "MTFP1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTOR", "MTPAP", "MTPN", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MXRA7", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NENF", "NF1", "NFRKB", "NFS1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NKRF", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPLOC4", "NPM1", "NRDC", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C3A", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "OAT", "OBSL1", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANX1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PECR", "PEF1", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMK", "PON2", "POP1", "POR", "PPAN", "PPCDC", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRELID3B", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PVR", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB29", "RAB2A", "RAB31", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABAC1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RARS", "RARS2", "RB1", "RBBP5", "RBBP7", "RBFA", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REEP6", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF2", "RNF40", "RNMT", "RNPS1", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARAF", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF8", "SCAMP3", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDE2", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A4", "SLC30A5", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP47", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX19", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "ST3GAL4", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STAU1", "STEAP3", "STIM1", "STIM2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TAF15", "TAF5", "TAF6L", "TAMM41", "TAP2", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TEAD1", "TECR", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX2", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM10B", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM14C", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRIM13", "TRIM25", "TRIM28", "TRIO", "TRIP10", "TRIP12", "TRIP13", "TRMT10C", "TRMT112", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPAN10", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TST", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUBGCP5", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAC2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFM1", "UGCG", "UGGT1", "UGT8", "UHRF1", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS13C", "VPS13D", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "WAPL", "WARS2", "WASF2", "WASHC3", "WBP11", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF131", "ZNF207", "ZNF326", "ZNF622", "ZNF638", "ZNF830", "ZPR1", "ZW10", "ZYG11B", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABHD12", "ACAD11", "ACADVL", "ACBD3", "ACBD5", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL1", "ADPGK", "AFG3L2", "AGK", "AKAP8", "AKT2", "ALDH3A2", "ALG1", "ALG11", "ALG12", "AMFR", "ANAPC16", "ANAPC4", "ANKLE2", "ANKRD13A", "ANO6", "AP3D1", "AP3S1", "APOO", "APOOL", "ARL6IP1", "ARMC10", "ASAH1", "ASNA1", "ASPH", "ATAD1", "ATAD3A", "ATAD3B", "ATG9A", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATPAF1", "ATXN10", "AUP1", "B4GALT1", "B4GAT1", "BAIAP2", "BCAP31", "BCCIP", "BCL2L13", "BCS1L", "BNIP1", "BSG", "BUB1B", "C12orf73", "C14orf2", "C19orf70", "CACYBP", "CALU", "CANT1", "CANX", "CAPZB", "CCDC47", "CCNK", "CD47", "CDC20", "CDC23", "CDC27", "CDIPT", "CDK4", "CDK5", "CDK9", "CDKAL1", "CDS2", "CELF1", "CEPT1", "CERS1", "CERS2", "CHST14", "CHUK", "CKAP4", "CLCC1", "CLCN3", "CLCN7", "CLN5", "CLN6", "CLPTM1", "CNOT9", "COA3", "COA7", "COG3", "COPS3", "COPS4", "COPS5", "COPS6", "COQ8A", "COQ9", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX7A2L", "CPOX", "CPT1A", "CPT2", "CRTAP", "CSNK2A1", "CTNNB1", "CTNND1", "CTSA", "CTSC", "CYB5B", "CYB5R1", "CYP51A1", "DAGLB", "DCTN2", "DCTN3", "DERL2", "DHCR24", "DHCR7", "DHDDS", "DHRS7", "DHRS7B", "DIABLO", "DNA2", "DNAJC1", "DNAJC11", "DNAJC19", "DOLPP1", "DPAGT1", "DYM", "ECE1", "EI24", "EIF2B2", "EIF2B5", "ELP2", "ELP3", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EPDR1", "EPHA7", "EPHX1", "EPPK1", "ERAP1", "ERAP2", "ERGIC1", "ERGIC2", "ERGIC3", "ERMP1", "ERO1A", "EXOC1", "EXOC7", "EXT2", "FADS2", "FAF2", "FAM162A", "FAM3C", "FAM8A1", "FAR1", "FDFT1", "FECH", "FIS1", "FKBP14", "FKBP7", "FLCN", "FOXRED1", "FUCA2", "FUNDC2", "GAA", "GALNT1", "GALNT4", "GBA", "GDAP1", "GEMIN8", "GGCX", "GHITM", "GJA1", "GLG1", "GLUD1", "GM2A", "GNG12", "GNG5", "GNPAT", "GNS", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPR107", "GPR108", "GPX8", "GRSF1", "GSK3A", "GSK3B", "GTF2H1", "GUSB", "HACD2", "HACD3", "HADH", "HADHA", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HDAC1", "HDAC2", "HGS", "HIGD1A", "HK2", "HLA-A", "HLA-C", "HMGCR", "HMOX1", "HMOX2", "HNRNPA3", "HNRNPAB", "HNRNPM", "HPS6", "HS2ST1", "HSD17B11", "HSD17B12", "HSDL1", "HSDL2", "HSPA13", "HTRA2", "ICMT", "IER3IP1", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "INA", "ING5", "ISOC1", "ITM2B", "ITM2C", "ITPRIP", "JAGN1", "JAK1", "KDELR1", "KDELR3", "KDSR", "KIF1A", "KLC2", "LAMP1", "LAMP2", "LBR", "LDAH", "LEMD2", "LETM1", "LGALS3BP", "LMAN1", "LMF2", "LNPEP", "LNPK", "LPCAT1", "LPGAT1", "LRRC59", "LRRC8C", "LTA4H", "LYSMD3", "MAGT1", "MAIP1", "MAN2A1", "MAVS", "MBOAT7", "MCL1", "MESD", "METTL7B", "METTL9", "MFN1", "MFSD10", "MGAT2", "MGST2", "MIA2", "MIA3", "MICU1", "MICU2", "MIEF1", "MIF", "MIGA1", "MINDY3", "MMGT1", "MORF4L1", "MPC2", "MPDU1", "MPV17", "MPV17L2", "MRPL10", "MRPL22", "MRPL23", "MRPL40", "MSMO1", "MSTO1", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTG1", "MTOR", "MTX1", "MTX2", "MUL1", "MXRA7", "NAA10", "NAA50", "NCEH1", "NCLN", "NCSTN", "ND1", "ND5", "NDC1", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA8", "NDUFAF1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS2", "NEDD4L", "NEFL", "NIPSNAP1", "NIPSNAP2", "NNT", "NONO", "NPC1", "NRM", "NUCB1", "NUCB2", "NUDT9", "NUP107", "NUP133", "NUP160", "NUP35", "NUP37", "NUP43", "NUP54", "NUP85", "NUPL2", "OCIAD1", "OPA1", "OPA3", "OSBPL11", "OSBPL2", "OSBPL8", "OXA1L", "P3H1", "P3H4", "P4HA2", "PANX1", "PARL", "PCM1", "PCYOX1", "PCYOX1L", "PDCD6", "PDK1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFDN2", "PFDN5", "PGRMC1", "PGRMC2", "PHB2", "PI4K2A", "PIGG", "PIGK", "PIGU", "PISD", "PITPNB", "PKMYT1", "PLD3", "PLD6", "PMPCA", "POLRMT", "POMK", "PON2", "POR", "PPP3CA", "PPT1", "PRAF2", "PRCP", "PREB", "PRELID3B", "PREPL", "PSAP", "PSMB2", "PSMB5", "PSMB6", "PSMD14", "PSPC1", "PTDSS2", "PTGES2", "PTPMT1", "PXMP2", "RAB10", "RAB12", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB29", "RAB2A", "RAB31", "RAB3B", "RAB5A", "RAB7A", "RAN", "RCN2", "RDH11", "RDH13", "RDH14", "REEP2", "REEP3", "REEP4", "REEP5", "REEP6", "RER1", "RFT1", "RFTN1", "RHBDD2", "RIPK1", "RMDN3", "RMND1", "RNF40", "RPN1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "SACM1L", "SAMM50", "SAR1A", "SAR1B", "SARAF", "SC5D", "SCAMP3", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCO1", "SCO2", "SDF4", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23IP", "SEC24A", "SEC61A1", "SEC62", "SEC63", "SEL1L", "SEPT6", "SEPT7", "SERAC1", "SET", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3GLB1", "SIGMAR1", "SIRT2", "SLC19A1", "SLC25A10", "SLC25A11", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC2A4", "SLC30A5", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A14", "SLC44A1", 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41.71116504854369 1.2957221273899948 0.3267733012969381 7.788084220174416 5.097264791179653 1.6571109350293016 0.3632481416270505 0.0001582610825807 1.0 0.3096866051250833 0.0239861063430982 7.920084898552539e-07 +Tetrapyrrole binding 9 17 3.629372975792719 0.0002841104926514 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 3.166933515555171e-05 0.0021781449325651 0.0016915485936643 4.084602018344024e-05 0.0002197719354354 +Metal ion transmembrane transporter activity 19 30 3.559798623998118 0.0003711392833269 9.563106796116504 24.67233009708738 0.8657396859235934 0.3700615753207195 4.93288923178502 4.839352380624028 1.4450904591933955 0.3424002804304004 0.0069704350000214 0.4463627535095094 0.1101605797563029 0.172108822769145 0.0007592154201828 +Passive transmembrane transporter activity 20 40 3.451868945507796 0.0005567180587247 10.728155339805824 34.00242718446602 0.8598494327527568 0.3171523987434088 5.464704354730218 4.259483301090722 1.5882390061019254 0.3339692919660049 2.746894024991849e-05 0.4243503559946278 0.0045581119989154 0.001715784629106 1.9423868048335755e-06 +Proton transmembrane transporter activity 19 36 3.396738657761864 0.0006819406204756 12.769417475728156 35.478155339805824 1.2352045534927034 0.2879171268332734 5.319202861157036 2.7149368379617917 1.7021108079122016 0.3308025072902738 9.722270349728632e-08 1.0 0.1563084442837106 0.0003907769995998 8.686358282039728e-09 +Secondary active transmembrane transporter activity 17 23 3.348400427783611 0.0008127948180127 9.080097087378642 21.490291262135923 1.2627683473613005 0.2947710034053126 5.466215032972134 3.0675886156990426 1.4241587428281404 0.3340388164945335 0.0190992235873082 1.0 0.5703677906367757 0.3571368988977866 0.0002847267225419 +Organic acid transmembrane transporter activity 17 22 3.1104287544833698 0.001868159566932 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0010667223886065 1.0 0.1365892396200844 0.0814773755217055 0.0051385782863233 +Nucleobase containing compound transmembrane transporter activity 11 14 3.0517604686255764 0.0022750356838707 6.529126213592233 14.04126213592233 1.4296604886183193 0.212054291115069 3.2696940585469636 1.915888183904924 1.3255809572534116 0.2748813593420038 1.8133319850769445e-07 1.0 0.0369282917904302 0.0069928111010265 1.3018918173659768e-08 +Steroid binding 11 20 3.0060048480381 0.0026470477738942 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 0.0004854168565433 0.2107016729382093 0.0789867722235121 0.0001580597168237 2.508443709806334e-06 +Oxidoreductase activity 67 234 2.9651289928124167 0.0030255603813682 52.54126213592233 227.42961165048544 0.490492706528076 0.5955656171597654 20.033606385640603 16.688970744458114 1.2909283370539455 0.4039853598071011 9.682652301333748e-14 7.109535134557627e-05 9.484046175263978e-06 2.1124459194039249e-10 4.1544657734139683e-13 +Organophosphate ester transmembrane transporter activity 10 12 2.9586822444982084 0.0030895749572732 5.665048543689321 12.143203883495143 1.4298365636921646 0.2056324024803549 3.029697948284232 1.927415248708952 1.2819429632405106 0.2680490563295835 5.11201442156503e-08 1.0 0.0182841548675732 0.0017174581383874 1.2871197665724932e-09 +Nucleotide transmembrane transporter activity 10 12 2.9586822444982084 0.0030895749572732 5.606796116504855 12.029126213592232 1.4217258291760082 0.2036087501116975 3.0234925518113496 1.8899648667798992 1.291115513359647 0.2666064512499804 3.1255992494602466e-08 1.0 0.016724444992627 0.0014320459890063 6.726091361467717e-10 +Primary active transmembrane transporter activity 26 58 2.932841498522614 0.0033587531439336 17.696601941747574 52.529126213592235 1.0080198242353189 0.3544097082146772 7.649017203625277 6.455721193615876 1.66885648871365 0.3767837436492733 1.2550271743823336e-05 0.0197758267942588 0.005659652817264 3.124888785850484e-05 1.0440666336715634e-06 +Inorganic anion transmembrane transporter activity 11 23 2.89709398664391 0.0037663690185774 7.427184466019417 19.274271844660195 1.0921593405593897 0.2441056926448881 3.717191605498929 3.7816647851785734 1.4014196343960104 0.2816216967014333 2.2415646360851995e-05 0.2220822570468345 0.0001281768423087 0.0014919193154812 4.915457973009443e-06 +Lipid binding 36 142 2.871777314952959 0.0040817047934371 30.883495145631063 138.65533980582524 0.9844637598707308 0.4289871747751645 8.92748670410201 14.760635317682617 1.446857667744565 0.4068298387995807 0.0073781990606275 0.3669518171170796 0.1352125747145023 0.0239737682416643 0.000975835802212 +Protein carrier chaperone 5 14 2.7878535191291705 0.0053058528616412 3.3980582524271843 10.118932038834952 0.8288787693114796 0.3398938251553178 1.8569721980092944 2.0920401213092656 1.1849901066971258 0.3127406939001886 3.782863969644887e-05 0.083126337411673 0.0006140521777265 2.7013551728451183e-06 0.0001382662061028 +Protein transporter activity 13 14 2.777401070918344 0.0054795517927872 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 3.001374474122689e-05 0.0063255491406275 0.0233124310373507 0.0028063338575205 1.347407131303299e-06 +Carbohydrate derivative transmembrane transporter activity 8 10 2.7325763286679288 0.0062841108824986 4.672330097087379 10.12135922330097 1.0096229459917263 0.2944050311743799 2.686158589641687 1.471354338494036 1.2935479322863277 0.3146313980204608 3.973230167948118e-05 1.0 0.2202973788945578 0.1292409073430241 1.973347558523223e-06 +Oxidoreduction driven active transmembrane transporter activity 10 34 2.7035033047403343 0.0068612765710991 9.733009708737864 29.83252427184466 0.7626445826297276 0.3795490924215395 4.629116134249794 3.4519743101246267 1.4198222355288384 0.35536187545778 1.9516552885733185e-05 0.0032330061916283 0.0028160479494861 1.988202176473063e-06 3.312285052312118e-05 +Glycolipid binding 7 11 2.6968669936420784 0.0069995221695229 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 7.662503280121292e-08 0.0029386578360865 0.0005152543640852 1.837861939916845e-06 2.269129992872316e-08 +Membrane insertase activity 4 11 2.6899708901481825 0.0071458252059231 2.737864077669903 7.388349514563107 0.8099367695235317 0.306513025583228 1.5809003521008822 1.7333564146948666 1.2685525479217892 0.3048480656363501 0.0001200304486802 0.0652597674910206 0.0002815881021324 1.31526437712885e-05 0.0003569480206607 +Hexosyltransferase activity 18 40 2.678924243468346 0.0073859102056828 9.633495145631068 33.87864077669903 0.7349501031127185 0.3949358882560483 4.261380470236419 4.330948695045228 1.2646745007039175 0.3422146027467064 0.0304417614049203 0.4243503559946278 0.6657439818035535 0.5218778121271003 0.0032904453979488 +Lipid transporter activity 14 22 2.6728430969134656 0.0075211419547709 6.546116504854369 19.805825242718445 0.7389006587243017 0.301332987440896 3.074370954053146 3.741159812966952 1.4134673193588587 0.2984913911167897 0.0089635173370504 1.0 1.0 0.2842397918791121 0.0010971316488104 +Monooxygenase activity 5 8 2.667589254400226 0.0076397593895229 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 0.0004502657659662 0.0002813337316999 4.804434222341775e-06 0.0004102788019959 0.0015223043876768 +Purine nucleotide transmembrane transporter activity 7 9 2.6337965298341657 0.0084436070306981 4.334951456310679 9.441747572815531 0.9917737457277228 0.2833655940290197 2.4104227054611673 1.6217588601139772 1.262135146193827 0.3001583617421954 1.7418062222765665e-05 1.0 0.1419203898220533 0.0557098434243155 2.538399058681183e-07 +Anion channel activity 7 13 2.633488256383544 0.0084512758277059 4.20873786407767 11.21116504854369 1.03959259790327 0.2192420598609839 2.3076742714116403 2.0905640066649145 1.3937691950814175 0.2662450395835827 0.0005548107931337 0.1263420182810564 0.0001322789716162 0.0004897389809093 3.6656062743218894e-05 +O acyltransferase activity 8 15 2.622539037946412 0.008727726842425 4.711165048543689 12.395631067961164 0.9877600518928406 0.2684789023147002 2.6842893514436073 2.3496085895491885 1.2379749168209273 0.2720543739153138 0.0001666980232874 0.1430638950507344 0.2638774705145789 0.0411512789917762 0.0001045874172425 +Sphingolipid binding 4 8 2.599193090386989 0.0093443195122151 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.0004525401183384 0.0032958763634803 2.1265295896701374e-05 5.200397996359343e-05 0.0001382662061028 +Phosphatidylcholine binding 4 9 2.557847979818397 0.0105322123462625 2.2524271844660193 7.929611650485437 1.2697801287388335 0.1567893034984199 1.081337239384838 1.04388968498945 1.4953842980517238 0.2256102823610289 0.0026603777148307 0.0742352733278267 0.0098557770733155 0.0061570039439817 0.0007186517412764 +Protein transmembrane transporter activity 7 10 2.5509639925408227 0.0107425423817879 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 2.605481586669537e-05 0.0029386578360865 0.0111011801010317 0.0073447144383531 7.441528927979243e-06 +Phosphotransferase activity for other substituted phosphate groups 4 8 2.538144229632584 0.0111442046315894 1.9053398058252424 5.174757281553398 0.0857884151299792 0.4696075786898813 1.1939453367119757 1.5543686288302525 1.070932812476897 0.3031413201326607 0.0009776198561721 1.0 1.0 0.0014320459890063 0.0027409433744388 +Antiporter activity 7 11 2.5288420230698576 0.0114439524119351 4.621359223300971 10.405339805825244 1.056576117278179 0.2813324268221227 2.679901841610502 1.304685592846984 1.2558310293487471 0.3063102364368053 0.1862763003278379 1.0 0.3116816529125438 0.6149168035506691 0.0004542491679055 +Peptidase activity 37 108 2.456981250942094 0.0140109998804616 29.021844660194176 113.626213592233 1.2572335980018865 0.3731282983707893 8.334453494010912 9.805689463637474 1.5136028692995414 0.3922229485757941 0.0314142566944743 0.4116361790609809 0.7710385308801245 0.1686632892813183 0.0141368704736407 +Macromolecule transmembrane transporter activity 7 11 2.455153724326181 0.0140824353380795 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 7.400221131341273e-05 0.0040679264544396 0.015225007352257 0.0116756742779249 2.6131601312709008e-05 +Endopeptidase activity 21 62 2.440543715223244 0.0146651708957585 19.08495145631068 62.800970873786405 1.5604938505680932 0.2935756148549138 5.629332570724372 6.156865220927466 1.27979578418692 0.359984229645684 0.0536608536965679 0.1896040470106967 0.4707704242707984 0.0478203719562379 0.0580158210477148 +Voltage gated anion channel activity 5 7 2.4377755769156444 0.0147779454375445 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 0.0003684617786793 0.0470522829573702 9.54357461344528e-05 0.0014684283121974 2.1795177811063544e-06 +Serine hydrolase activity 10 21 2.428816288932357 0.0151482058566625 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 0.0355283590256662 0.2068720246529641 0.3686542667111886 0.0057706709278987 0.026951393323143 +Molecular transducer activity 12 32 2.422816363793152 0.0154007095361239 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 0.7763639117135418 1.0 0.9177516242521486 0.874110249605411 0.7069779159946722 +Ceramide binding 4 6 2.4181693100529107 0.0155988168604681 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 7.965265001886016e-05 0.0017062060788896 5.153776434246189e-06 8.624555272386569e-06 0.0002388933667028 +Glycosyltransferase activity 18 55 2.3962421970183314 0.0165641411666652 10.808252427184469 46.75 0.6230735361107147 0.5000303532444054 4.489970468729936 5.6981622825309435 0.9932734853426128 0.358363386747457 0.0079361432643587 0.5379013390171795 0.7838647271589982 0.338502525065574 0.0017002787637819 +Gated channel activity 7 13 2.3911648697426355 0.016795009070073 4.317961165048544 13.019417475728156 0.8697524591818097 0.2583579989367679 2.2914716766946497 2.0107989163575497 1.3733766112751231 0.2762671399351702 0.0786856434528199 0.2516504230112798 0.0024974565689748 0.0564393829037643 0.0247138189179858 +Cation channel activity 9 23 2.376221498610229 0.0174909596758863 6.628640776699029 20.20145631067961 0.2168681550185727 0.4203796109119975 3.66569707500714 2.3934980322982335 1.245793992642405 0.316602380113191 0.007085762754376 1.0 0.5083206499791918 0.2645177746775517 0.0027861506003522 +Symporter activity 7 10 2.35677018715916 0.0184346514984319 3.638349514563106 9.1747572815534 0.9770544165414302 0.3122690599192905 2.3735568316725377 2.065327188945721 1.1044541290009051 0.3081067804681572 0.0254774575922873 1.0 1.0 0.2871762535363917 0.0593289293974866 +Lamin binding 3 8 2.3365201850930544 0.0194641468447767 3.174757281553398 8.133495145631068 0.8401140072225439 0.3634406451484216 1.8429987407927015 0.9675032512806204 0.9823145131994128 0.293984725882831 0.0020567301082413 1.0 1.0 0.0050923434600555 0.0047772438954047 +Calcium ion transmembrane transporter activity 8 15 2.3271244667408637 0.0199586416567616 4.682038834951456 13.276699029126211 0.2388683150344522 0.4966462427664995 2.540615268048159 1.6898155172183935 1.0404105676043174 0.3190267550516111 0.2675241254936886 1.0 0.36256189343107 0.6835238209809511 0.0245462392153625 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 9 29 2.3238657706100803 0.0201326893322384 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.0028470506592486 0.0099984448704361 0.0018864367993581 0.0017840783970447 0.0050138363947049 +Lipase activity 8 18 2.316075191727402 0.0205541635719672 4.160194174757281 17.95145631067961 -0.3883889220249866 0.2447386375427953 2.2541370727794456 2.684470408535888 1.602380040893784 0.2433104127648577 0.0743386516469415 0.0028071579475431 0.0184792322064663 0.1700362094205073 0.0227402044332229 +Vitamin transmembrane transporter activity 5 7 2.3002001351703134 0.0214368841795924 2.7766990291262137 6.252427184466019 1.4438342367310928 0.182339474606115 1.52603324115363 1.3650879028699858 1.0282691527982806 0.2346378729908682 0.0005950488033824 1.0 0.1662183776826317 0.000963248429344 0.0001939038931951 +Solute cation symporter activity 7 9 2.297008161054882 0.0216183041823405 2.854368932038835 7.206310679611651 0.8639239563858236 0.3319920905256767 1.9640347167867271 2.0653542869596597 1.117186698589392 0.3146562336443082 0.0078273399170881 1.0 1.0 0.1887844423268079 0.0198874102408346 +Fad binding 7 11 2.284946314001874 0.0223159758935458 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.0027002517582552 1.0 0.2202973788945578 0.4704807306772423 0.0072634035650054 +Snap receptor activity 10 14 2.27819541814782 0.0227149371534338 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 0.0088955425406483 1.0 0.0412617301526311 0.0012324742743759 0.005197217830129 +Voltage gated channel activity 7 11 2.272858369492311 0.0230347162316055 3.2257281553398056 10.116504854368932 0.8578192560085278 0.2690365421745596 1.8168622808181427 1.411127559025233 1.234834479111217 0.2694186191218866 0.0395595995112291 0.151306852499084 0.0040337600577914 0.0479498850625808 0.005197217830129 +Cholesterol binding 5 11 2.244023049388537 0.0248309183629964 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 0.0263164558235643 0.134742527043449 0.032784445092202 0.0348798008289802 0.0027009397323495 +Dicarboxylic acid transmembrane transporter activity 6 8 2.232250809224256 0.0255983910189656 2.842233009708738 7.20873786407767 1.0708946030323223 0.2426579907451208 1.9772646753006824 0.7975212565102757 1.0844681659651012 0.2564515003952125 0.0214626028283106 1.0 0.1419203898220533 0.3236592382947187 0.0391317335840731 +Sodium ion transmembrane transporter activity 3 8 2.226614153408351 0.02597307222128 3.033980582524272 6.733009708737864 0.6330876716410718 0.3951789521880264 1.773267150762252 1.4834287460359985 1.0827590126064015 0.3202441368223486 0.1960803346993585 1.0 1.0 0.6242434222626774 0.1254299298894934 +Sterol binding 8 15 2.2164115820147554 0.026663327203481 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 0.0473710132076872 0.1594721229818057 0.0457762537637492 0.0552623668853733 0.0014381321258029 +L amino acid transmembrane transporter activity 5 8 2.207526963443389 0.02727726537744 3.628640776699029 8.201456310679612 0.919975936290114 0.2876791162304417 2.2759730869054327 1.0290432051153906 1.15482978403653 0.2925518180165951 0.3051419944346806 1.0 1.0 0.154226710893935 0.4115219783459027 +Prenyltransferase activity 5 7 2.198717345465106 0.0278980268159927 2.099514563106796 6.009708737864078 0.6003375563696288 0.3888587975741492 1.4081247453019228 2.026499903013553 1.0962032128239394 0.3008779016140248 0.1104430428419075 1.0 1.0 0.0495157384890535 0.1615113588580296 +Phospholipid binding 20 91 2.1940684628477656 0.0282304880848431 18.890776699029125 88.4635922330097 0.777309720287493 0.452120200534915 6.970479526806733 10.51702894240924 1.1988133109990275 0.3785217149858343 0.1173268659921313 0.1766231774438927 0.0248325777482642 0.0620780551805057 0.0587505295684527 +Molecular carrier activity 14 35 2.168703562579887 0.0301051967462717 8.985436893203884 32.922330097087375 0.4263347027610819 0.5995318029338973 4.267144921372851 3.1428430650945036 0.9199841946557948 0.3455794463799358 0.0057687447197415 0.2406936845278361 0.0168596271371444 0.0024061053673092 0.0014977097109146 +Atp transmembrane transporter activity 5 6 2.149572280700243 0.0315890629742912 3.058252427184466 5.456310679611651 0.5680189081478334 0.3318090311699867 1.598392655736251 0.6936144116307477 1.3025695117924114 0.3140848719976767 0.0001305701149647 1.0 0.073646168181401 0.1775366954381628 3.1584848551264776e-07 +Transition metal ion transmembrane transporter activity 4 5 2.1487024257101432 0.031657996290096 2.2597087378640777 4.444174757281553 1.267846808399692 0.205487024774009 1.5353529408674886 1.9618423203326616 1.2931295194130703 0.2516620757205828 0.0018579158445701 0.1093006244161378 0.0215793786244467 0.0193169154759243 0.0050807822676514 +Phospholipid transporter activity 7 11 2.1220089350661877 0.0338369877260991 2.1771844660194173 6.699029126213592 0.5736831867868913 0.3651436001806147 1.523334307555052 1.8451455672114891 1.0803825413008894 0.2760174807519195 0.0088955425406483 1.0 1.0 0.5647101544543685 0.0010074664531997 +Alcohol binding 6 15 2.1187645025701585 0.0341103740744654 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.0413530824951619 0.2145132052152406 0.0817843887075946 0.1193188519501932 0.0096315213740099 +Iron ion binding 7 20 2.0717755478509807 0.0382863780653688 6.524271844660194 22.196601941747577 0.9076096695164306 0.382669917893863 2.4429198675966717 3.289094676807881 0.9378690899634522 0.3126784916965753 0.0285031054487893 0.2552681350600493 0.1143886596739273 0.0155889061230085 0.0086065745362448 +Wide pore channel activity 4 6 2.062980374547513 0.0391144928259332 2.157766990291262 4.266990291262136 1.156945559067054 0.1661436788367006 1.073449599559222 0.4792567768515825 1.4176309163665306 0.2377490100494037 4.06413421048409e-06 0.0378187125466048 4.515786717225142e-05 0.0007102815399137 1.2721849129246575e-05 +Abc type transporter activity 7 9 2.046500620542103 0.0407071414750608 3.0194174757281553 7.652912621359223 0.9831250219385844 0.2361571806590424 1.9482657586917436 2.350049836723345 1.2743804993059251 0.258194993176919 0.0685757512594111 1.0 1.0 0.4573561220916043 0.0302721435688183 +Quaternary ammonium group binding 5 14 2.0283601601133334 0.0425235030789217 2.8567961165048543 12.12864077669903 0.9707568143407772 0.2573327609820879 1.4849985868988949 1.260087490061347 1.304146106648176 0.2795917987269193 0.0089213648122906 0.1006582454154426 0.0182841548675732 0.0152248647419399 0.0004711940976389 +Intramembrane lipid transporter activity 3 5 2.025159339324309 0.0428510053484596 1.385922330097087 3.5849514563106797 0.6981989398710021 0.2957392957485286 1.1208941791969826 1.4021712523598824 1.3078360822178663 0.2625886724506013 0.0051742294315912 1.0 1.0 0.3715199079432311 0.0116417512175889 +Atpase coupled transmembrane transporter activity 14 24 1.997300164854638 0.0457925854693617 8.072815533980583 22.696601941747577 0.8561067713091313 0.3392846662603397 4.166386392056555 3.892074110340729 1.3163009809214623 0.3229730128136945 0.0701263908386188 1.0 0.4264955437255276 0.410005165463368 0.0063512884491436 +P type transmembrane transporter activity 4 6 1.982998558965076 0.0473675905034485 2.842233009708738 5.473300970873787 0.6050493013674468 0.3730987003611934 1.6045635356324264 1.3712604140019378 1.17652933932801 0.3174788438558891 0.0747757989798899 1.0 0.1084298440104649 0.2541534411772372 0.0177300896528831 +Proton transporting atp synthase activity rotational mechanism 5 12 1.9798086997654876 0.0477250284508541 3.655339805825242 10.75485436893204 0.46898650441807 0.3141755537304957 2.268964442606705 0.8649601417133376 1.3429609354721883 0.2856466957651606 1.7418062222765665e-05 1.0 0.1419203898220533 0.0061570039439817 6.478838546237441e-05 +Proton channel activity 5 12 1.9798086997654876 0.0477250284508541 3.655339805825242 10.75485436893204 0.46898650441807 0.3141755537304957 2.268964442606705 0.8649601417133376 1.3429609354721883 0.2856466957651606 2.605481586669537e-05 1.0 0.1500965904253892 0.0073447144383531 9.60684890252726e-05 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..4830da10ffab2a4b62f6391b28f1a438838556a6 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 1383, + "title": "Average number of proteins per term", + "value": 16.458423716558208 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4e8c2b6f7a9ec55dc10755620f08874b7f3dc418 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9aa6f51b95a1a271d81dd1ef0b79ae6d7bd725db --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,373 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter activity 0.629443755778778 6.504454557525523 7.797578269390938e-11 1.0784050303809367e-07 1.0784050884867668e-07 188 Q99595,Q9BVC6,O96000,P45880,O95139,O43676,P03886,Q8WWI5,Q8N4V1,Q9NS69,Q9Y277,P17302,P21796,Q86VD7,P20674,Q9H2D1,P20020,Q9H936,Q9UBX3,P23634,O75964,P13073,O75027,Q9H9B4,Q8TAD4,Q9C0H2,Q9H2V7,P16615,Q9Y5J6,Q93050,O95563,P00846,O14925,O14975,P04062,O15173,O95169,P36542,P51970,Q00535,Q9BZF1,Q9Y3B1,O95298,Q7KZN9,P51991,Q9Y6M9,Q9HC21,Q96AA3,P39210,Q9HD23,P00403,Q9BXB4,Q9HD20,Q02978,Q96ES6,Q6P4A7,Q9P0J0,Q8TDW0,Q70HW3,P17900,P30825,O00483,P28288,P38435,Q96S66,P03915,Q9BXP2,Q96QD8,Q9UJS0,Q8TB61,Q14728,Q15388,Q9UDW1,L0R6Q1,Q8WTV0,O75746,Q9Y5J9,Q07820,Q00325,Q9Y487,P14672,P53007,Q8NE01,Q13423,Q4KMQ2,P33527,O95168,Q7L0J3,P41440,P08183,Q96RD7,P12235,O15118,P24539,P98194,P49755,Q9BQT8,Q9H2J7,Q9BSK2,P56385,Q03519,O43681,Q15043,Q6NUK1,Q7Z3C6,O43808,O96008,Q9H0U3,P56134,Q9Y6M7,Q96NB2,Q00169,P12236,O95202,Q8IXU6,Q8NBU5,P48739,P51790,Q9UM00,O14678,P51798,P61619,Q9H1P3,Q9UGP8,P05141,P05023,O75306 127 +Ion transmembrane transporter activity 0.6533476689852923 5.626163138534878 1.8426209231516888e-08 2.5483122903059813e-05 8.494482456190284e-06 109 Q96NB2,Q9BVC6,Q7KZN9,Q9Y487,P12236,P45880,O95202,Q9HC21,Q13423,Q4KMQ2,P41440,Q8WWI5,Q8N4V1,P00403,P51790,Q9HD20,Q96RD7,Q96ES6,Q6P4A7,P12235,Q9Y277,P24539,P17302,P21796,Q9UM00,Q86VD7,Q70HW3,P20674,Q9H2D1,P20020,P98194,P30825,Q9H936,Q9UBX3,Q9BQT8,P23634,Q9H2J7,O75964,P51798,P61619,P56385,Q96S66,P13073,O43681,Q15043,Q9H9B4,Q6NUK1,Q8TAD4,Q9C0H2,P16615,Q96QD8,Q93050,O43808,P00846,Q9H0U3,P56134,Q8TB61,P05141,P05023,Q9Y6M7,P36542,Q9UDW1 62 +Cation transmembrane transporter activity 0.665124788223115 4.7456731151973095 2.078140894479219e-06 0.0028699456528856 0.0007185172142665 76 Q96NB2,Q9Y487,Q7KZN9,O95202,Q9HC21,Q13423,Q4KMQ2,Q8WWI5,Q8N4V1,P00403,P51790,Q9HD20,Q96RD7,Q96ES6,P12235,P24539,Q9UM00,Q70HW3,Q86VD7,P20674,P20020,P98194,P30825,Q9H936,P23634,Q9H2J7,O75964,P61619,P56385,P13073,Q15043,Q8TAD4,Q96QD8,P16615,Q93050,O43808,P00846,Q9H0U3,P56134,P05141,P05023,Q9Y6M7,P36542,Q9UDW1 44 +Inorganic molecular entity transmembrane transporter activity 0.6258174488450712 4.593395260381879 4.360919451773526e-06 0.0060130137872095 0.0012062303203608 84 Q7KZN9,Q9Y487,P45880,O95202,Q13423,Q4KMQ2,Q8N4V1,P00403,P51790,Q9HD20,Q96RD7,Q96ES6,P12235,Q9Y277,P24539,P21796,Q9UM00,P20674,P20020,P98194,Q9H936,Q9UBX3,Q9H2J7,O75964,P51798,P61619,P56385,Q96S66,P13073,O43681,Q15043,Q8TAD4,Q9C0H2,P16615,Q96QD8,Q93050,P00846,Q9H0U3,P56134,P05141,P05023,Q9Y6M7,P36542,Q9UDW1 44 +Anion transmembrane transporter activity 0.6790195753735768 4.309702557470031 1.6347426761154082e-05 0.022355015134313 0.0037680818684462 49 Q96NB2,P12236,P53007,P45880,Q9HC21,Q4KMQ2,P41440,P51790,Q02978,P12235,Q9Y277,Q8TDW0,P17302,P21796,Q86VD7,Q9H2D1,P30825,Q9H936,Q9UBX3,Q9BQT8,P51798,Q96S66,O43681,Q15043,Q9BXP2,Q6NUK1,Q9H9B4,Q9C0H2,O95563,Q96QD8,O43808,Q9UJS0,Q8TB61,P05141,Q14728,Q9Y6M7,O75746 37 +Active transmembrane transporter activity 0.564362256018135 3.867083911221915 0.0001101445368221 0.1413022522728552 0.0217614134892849 80 Q00325,O95298,Q7KZN9,O96000,P12236,Q9Y6M9,P53007,O95139,O95202,O43676,P03886,P33527,P41440,P08183,P00403,P51790,Q9HD20,Q02978,Q96ES6,P12235,Q9P0J0,O14678,P20674,P20020,P98194,O00483,Q9H936,Q9UBX3,P28288,P23634,Q9H2J7,P51798,P13073,O75027,P03915,Q03519,Q9BXP2,Q15043,P16615,Q96QD8,P05141,P05023,Q9Y6M7,O75306,O95169,Q15388,Q9UDW1,P51970 48 +Organic anion transmembrane transporter activity 0.7166524525285014 3.782814448224394 0.0001550650108141 0.1930322214055498 0.0261198519260427 31 Q96NB2,P12236,P53007,Q9HC21,P41440,Q02978,P12235,P17302,Q86VD7,Q9H2D1,P30825,Q9H936,Q9BQT8,Q9UBX3,Q6NUK1,Q9H9B4,O95563,Q96QD8,O43808,Q9UJS0,Q8TB61,P05141,Q14728,Q9Y6M7,O75746 25 +Active ion transmembrane transporter activity 0.6310145529360318 3.733464644198125 0.0001888637160234 0.2298909785267875 0.0261198519260427 44 Q7KZN9,P12236,O95202,P41440,P00403,P51790,Q9HD20,Q96ES6,P12235,P20674,P20020,P98194,Q9H936,Q9H2J7,P51798,P13073,Q15043,Q96QD8,P16615,P05141,P05023,Q9Y6M7,Q9UDW1 23 +Tetrapyrrole binding 0.8311298300457588 3.629372975792719 0.0002841104926514 0.3249581830167307 0.0357204373942654 17 O43169,Q6UW02,P09601,Q7KZN9,P53701,P30519,O15173,Q9H7Z7,O00264 9 +Metal ion transmembrane transporter activity 0.6965979518644514 3.559798623998118 0.0003711392833269 0.4015312101599984 0.0395100748193506 30 O95202,Q9HD23,Q8N4V1,Q96RD7,Q9HD20,Q9UM00,P20020,P98194,P23634,Q9H2J7,P61619,Q15043,Q8TAD4,P16615,Q96QD8,Q9H0U3,P05023,Q9Y6M7,Q00535 19 +Passive transmembrane transporter activity 0.6136529274992644 3.451868945507796 0.0005567180587247 0.5370589129774379 0.0395100748193506 40 Q9BVC6,P45880,Q4KMQ2,P39210,P51790,Q96RD7,Q9Y277,P24539,P21796,Q9UM00,P51798,O75964,P61619,P56385,Q96S66,Q9C0H2,P00846,O96008,P56134,P36542 20 +Proton transmembrane transporter activity 0.6212289624534229 3.396738657761864 0.0006819406204756 0.6107157964091514 0.0395100748193506 36 Q9Y487,Q7KZN9,O95202,Q13423,P00403,P51790,Q96ES6,P12235,P24539,P20674,O75964,P56385,P13073,Q93050,P00846,P56134,P05141,P36542,Q9UDW1 19 +Secondary active transmembrane transporter activity 0.7345096950127975 3.348400427783611 0.0008127948180127 0.6752021565665515 0.0395100748193506 23 P41440,Q9H936,Q9UBX3,Q9H2J7,Q00325,P51790,P51798,P12236,Q02978,P05141,Q96ES6,Q9Y6M7,P12235,O95202,Q15043,Q9BXP2,Q96QD8 17 +Organic acid transmembrane transporter activity 0.7057898515851916 3.1104287544833698 0.001868159566932 0.9246853825302253 0.0481642336686713 22 P41440,Q9H936,Q9BQT8,Q96NB2,Q9UBX3,Q9H2J7,P08183,O14975,Q9UJS0,Q02978,P53007,Q9H9B4,Q9H2D1,O75746,O95563,P30825,Q96QD8 17 +Nucleobase containing compound transmembrane transporter activity 0.804768543664014 3.0517604686255764 0.0022750356838707 0.9571461095326166 0.0528501702319799 14 P41440,O43808,Q9BSK2,P12236,Q8TB61,P12235,Q9HC21,Q86VD7,L0R6Q1,Q6NUK1,Q9H2D1 11 +Steroid binding 0.7051416643326675 3.0060048480380996 0.0026470477738942 0.974414279695206 0.0563210318660882 20 Q12770,P38435,P04062,P35610,O15173,O15118,P45880,Q14108,P21796,O00264,Q9H1P3 11 +Oxidoreductase activity 0.3887651132489215 2.9651289928124167 0.0030255603813682 0.9848642049320764 0.0564871195855094 234 O43169,Q96CU9,Q8NBM8,O00767,O95298,Q7KZN9,O96000,Q9Y6N5,Q9HBH5,Q15392,Q9UHQ9,Q8WWV3,Q9Y6M9,Q15067,Q9Y6N1,O95139,Q9H7Z7,O43676,P40939,P03886,Q14739,Q06136,Q13423,Q15800,Q8N0U8,Q8NBN7,P00403,P09601,Q9UHG3,P30519,Q16850,Q9P0J0,O43396,Q8NBX0,P51648,Q53GQ0,Q16836,Q9NZ01,Q3SXM5,Q9NRG7,Q6UW02,O75845,Q658P3,Q14534,P13073,O15254,P03915,P00367,Q709F0,Q8N4Q0,O15460,Q32P28,Q9Y394,Q8NBQ5,Q99735,Q9UBM7,P21912,P78417,Q96JJ7,O75306,O43819,Q9Y320,Q8TED1,Q9H3N1,Q9UDW1,P04035,P16435 67 +Organophosphate ester transmembrane transporter activity 0.8336969158026908 2.9586822444982084 0.0030895749572732 0.9861503662109056 0.0564871195855094 12 P41440,O43808,Q9BSK2,P12236,Q8TB61,P12235,Q9HC21,Q86VD7,Q6NUK1,Q9H2D1 10 +Nucleotide transmembrane transporter activity 0.8336969158026908 2.9586822444982084 0.0030895749572732 0.9861503662109056 0.0564871195855094 12 P41440,O43808,Q9BSK2,P12236,Q8TB61,P12235,Q9HC21,Q86VD7,Q6NUK1,Q9H2D1 10 +Primary active transmembrane transporter activity 0.5138272145874113 2.932841498522614 0.0033587531439336 0.9904667927491172 0.0580644449757527 58 O95298,Q7KZN9,O96000,Q9Y6M9,O95139,O43676,P03886,P08183,P00403,Q9HD20,Q9P0J0,O14678,P20674,P20020,P98194,P23634,P51798,P13073,O75027,Q03519,P03915,P16615,P05023,O75306,O95169,Q9UDW1 26 +Inorganic anion transmembrane transporter activity 0.6643695201286732 2.89709398664391 0.0037663690185774 0.994585757787569 0.0612810394434418 23 Q9UBX3,P51790,Q96S66,Q9Y6M7,Q9Y277,P45880,O43681,P21796,Q15043,Q4KMQ2,Q9C0H2 11 +Lipid binding 0.411229163087368 2.871777314952959 0.0040817047934371 0.996505446907133 0.065639508480507 142 Q9UM22,Q00169,Q8NFH5,O43292,Q15067,P45880,Q9BWH2,P50897,P48739,Q9Y371,P35610,O60313,O14735,O15118,P21796,Q14108,Q5T8D3,Q9H4A6,Q9H490,P38435,Q92543,Q99623,O15254,Q92643,Q9NZJ7,Q9H1P3,Q12770,O14773,P04062,O15173,Q13432,Q9NQZ5,P07602,O00264,Q9NWW5,Q8WTV0 36 +Protein carrier chaperone 0.7553776751184003 2.7878535191291705 0.0053058528616412 0.9993622286996856 0.0772411690193255 14 P40855,Q8N4V1,Q9NPA0,Q8N8Q8,Q15070 5 +Protein transporter activity 0.753454773869351 2.777401070918344 0.0054795517927872 0.999499077377009 0.0772411690193255 14 P49755,Q9Y5J6,Q8NBU5,Q9Y5J9,O96008,Q99595,Q9UGP8,P61619,Q07820,O14925,Q9HD20,Q9NS69,Q15388 13 +Carbohydrate derivative transmembrane transporter activity 0.8282226178348395 2.7325763286679288 0.0062841108824986 0.999836442780646 0.0782966247792405 10 P41440,O43808,P12236,Q8TB61,P12235,Q86VD7,L0R6Q1,Q6NUK1 8 +Oxidoreduction driven active transmembrane transporter activity 0.5478946943621956 2.7035033047403343 0.0068612765710991 0.9999267658709188 0.0828662179075012 34 P00403,O95298,Q7KZN9,O96000,P13073,Q9Y6M9,Q9P0J0,P03915,O43676,P03886 10 +Glycolipid binding 0.8027117828027348 2.6968669936420784 0.0069995221695229 0.9999395912719876 0.0830476996621147 11 P50897,Q9UM22,Q9H490,O14773,P07602,Q9NZJ7,Q9NWW5 7 +Membrane insertase activity 0.8013258258345811 2.6899708901481825 0.0071458252059231 0.9999507280358652 0.0830476996621147 11 Q15070,Q8N8Q8,Q9NPA0,Q8N4V1 4 +Hexosyltransferase activity 0.5233038813530851 2.678924243468346 0.0073859102056828 0.9999647351228956 0.0849830696981057 40 O43505,P13807,Q13126,Q93063,P04062,Q9BT22,Q8N4A0,P15291,Q10469,Q9BV10,P46977,Q16739,O75340,Q16880,P04843,Q2TAA5,Q8TCJ2,Q10472 18 +Lipid transporter activity 0.6383943759074906 2.6728430969134656 0.0075211419547709 0.9999707915658386 0.0852601583889197 22 Q9BZF1,Q96AA3,Q7Z3C6,P48739,Q9Y3B1,Q00169,P08183,O14975,Q9BXB4,O15118,P17900,O14678,Q4KMQ2,Q9H1P3 14 +Monooxygenase activity 0.8496978674050639 2.667589254400226 0.0076397593895229 0.9999752418051212 0.085900709233417 8 Q6UW02,Q15800,P09601,Q14534,P30519 5 +Purine nucleotide transmembrane transporter activity 0.8252884435278856 2.6337965298341657 0.0084436070306981 0.9999919278278908 0.0935049157577391 9 P41440,O43808,P12236,Q8TB61,P12235,Q86VD7,Q6NUK1 7 +Anion channel activity 0.748637809328839 2.6334882563835436 0.0084512758277059 0.9999920137101568 0.0935049157577391 13 P51790,Q96S66,Q9Y277,P45880,P21796,Q4KMQ2,Q9C0H2 7 +O acyltransferase activity 0.7034458408905476 2.622539037946412 0.008727726842425 0.9999945692238872 0.0936529116681191 15 P35610,Q9HCL2,Q86UL3,Q8NF37,P23786,O15228,Q96N66,Q92604 8 +Sphingolipid binding 0.8349379928996613 2.5991930903869895 0.0093443195122151 0.9999977031039796 0.0940479076043371 8 P45880,Q9UM22,P21796,Q9NZJ7 4 +Phosphatidylcholine binding 0.809384422656154 2.557847979818397 0.0105322123462625 0.999999562985264 0.0958292741768494 9 P45880,Q14108,P21796,Q00169 4 +Protein transmembrane transporter activity 0.7909619350774811 2.5509639925408227 0.0107425423817879 0.9999996743077432 0.0965259518965429 10 P49755,Q99595,O96008,Q07820,P61619,O14925,Q9NS69 7 +Phosphotransferase activity for other substituted phosphate groups 0.8218693801227387 2.5381442296325836 0.0111442046315894 0.9999998142674482 0.0987976602915915 8 Q9BVG9,Q9H3H5,Q5H8A4,Q9Y6K0 4 +Antiporter activity 0.7692794265217963 2.5288420230698576 0.0114439524119351 0.9999998778779317 0.1008088292083208 11 P41440,Q9UBX3,P51798,P51790,P12236,P12235,O95202 7 +Peptidase activity 0.3944382303830214 2.456981250942094 0.0140109998804616 0.9999999966497852 0.1106591367759316 108 P67812,P09960,Q9UIQ6,Q969V3,Q9BXS4,O43292,Q9HBH5,P55786,P49721,Q9HB40,Q6P179,Q9H8M7,Q70CQ2,O75844,Q4J6C6,P51784,Q7Z2K6,P28074,P36551,Q9NZ08,Q9H300,Q9Y4W6,Q7L5N1,Q96FZ2,Q92643,O00487,Q9NQH7,P42892,O14773,P10619,Q92905,P28072,Q10713,P42785,P53634,Q6NTF9,Q15005 37 +Macromolecule transmembrane transporter activity 0.7548357700010824 2.455153724326181 0.0140824353380795 0.9999999969692148 0.1106591367759316 11 P49755,Q99595,O96008,Q07820,P61619,O14925,Q9NS69 7 +Endopeptidase activity 0.4616218675601454 2.4405437152232436 0.0146651708957585 0.999999998662041 0.1122961458248575 62 P67812,Q9BXS4,O43292,P49721,Q6P179,Q70CQ2,O75844,Q4J6C6,P51784,P28074,Q9NZ08,Q9H300,Q9Y4W6,Q92643,P42892,O14773,Q10713,P28072,Q92905,P53634,Q6NTF9 21 +Voltage gated anion channel activity 0.8569487021568528 2.4377755769156444 0.0147779454375445 0.999999998857924 0.1122961458248575 7 P51790,Q9Y277,P45880,P21796,Q4KMQ2 5 +Serine hydrolase activity 0.6088039903288331 2.428816288932357 0.0151482058566625 0.9999999993209095 0.1141019151212973 21 P67812,O14773,P10619,Q9H300,Q4J6C6,Q9HB40,P42785,P53634,Q6PIU2,Q6NTF9 10 +Molecular transducer activity 0.5291348523468608 2.4228163637931517 0.0154007095361239 0.9999999995236633 0.1151307096673481 32 Q99442,Q15629,Q9UGP8,Q99720,O15173,Q9UKV5,Q9UBG0,O15118,Q14108,Q08722,Q9Y6I9,Q8WTV0 12 +Ceramide binding 0.910023344934798 2.4181693100529107 0.0155988168604681 0.9999999996393784 0.1159847511721906 6 P45880,Q9UM22,P21796,Q9NZJ7 4 +Glycosyltransferase activity 0.463838699540174 2.3962421970183314 0.0165641411666652 0.999999999907152 0.1186953742668293 55 O43505,Q9H3H5,P43490,P04062,Q9BT22,Q8N4A0,P15291,Q10469,Q9BV10,P46977,Q16739,Q11206,O75340,Q16880,Q2TAA5,Q8IXJ6,Q8TCJ2,Q10472 18 +Gated channel activity 0.7040118780743199 2.3911648697426355 0.016795009070073 0.999999999932895 0.1191480223599767 13 P51798,P51790,Q9Y277,P45880,P21796,Q4KMQ2,Q9C0H2 7 +Cation channel activity 0.5880027243870566 2.376221498610229 0.0174909596758863 0.9999999999747968 0.1227918641205623 23 P00846,O75964,P56385,P56134,Q96RD7,P24539,P36542,Q9UM00,Q4KMQ2 9 +Symporter activity 0.7520362298811621 2.3567701871591593 0.0184346514984319 0.9999999999933276 0.1287632475875321 10 Q9H936,Q9H2J7,Q96ES6,Q9Y6M7,Q9BXP2,Q15043,Q96QD8 7 +Lamin binding 0.7794002072711527 2.3365201850930544 0.0194641468447767 0.9999999999984368 0.1340235775923352 8 P42167,O94901,Q14739 3 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9868585732165204 2.3299541624760285 0.0198085738970283 0.9999999999990384 0.1349520083723658 2 P09601 1 +Calcium ion transmembrane transporter activity 0.6529755488701479 2.3271244667408633 0.0199586416567616 0.999999999999222 0.1353078500553988 15 P23634,P61619,Q96RD7,O95202,Q9UM00,P20020,P98194,P16615 8 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.5397512268088792 2.3238657706100803 0.0201326893322384 0.9999999999993914 0.1358219968121256 29 Q6UW02,Q15800,O00767,O75845,P09601,P30519,Q14534,Q16850,Q32P28 9 +Lipase activity 0.6086999065856524 2.316075191727402 0.0205541635719672 0.9999999999996644 0.1379922729127705 18 Q8N2A8,Q9NXE4,P09601,Q8IV08,Q8NCG7,Q8N2K0,Q6PIU2,Q9H6V9 8 +Vitamin transmembrane transporter activity 0.8264115486789532 2.3002001351703134 0.0214368841795924 0.9999999999999036 0.1408459168141502 7 P41440,P38435,P04062,Q9HC21,Q9H2D1 5 +Solute cation symporter activity 0.7558834829048247 2.297008161054882 0.0216183041823405 0.9999999999999254 0.1410288428498915 9 Q9H936,Q9H2J7,Q96ES6,Q9Y6M7,Q9BXP2,Q15043,Q96QD8 7 +Fad binding 0.721967469638763 2.284946314001874 0.0223159758935458 0.999999999999972 0.1448966885482342 11 Q96HE7,Q9Y6N5,Q14534,Q15392,O15254,Q9UHQ9,Q15067 7 +Snap receptor activity 0.6644523603741155 2.2781954181478197 0.0227149371534338 0.999999999999984 0.1461151538753443 14 O14653,O75396,Q9UNK0,O60499,O95249,Q12981,Q9P2W9,Q13190,O15400,O15498 10 +Voltage gated channel activity 0.7196588890317337 2.272858369492311 0.0230347162316055 0.99999999999999 0.1469650008331112 11 P51798,P51790,Q9BVC6,Q9Y277,P45880,P21796,Q4KMQ2 7 +Cholesterol binding 0.7141653626741445 2.244023049388537 0.0248309183629964 0.9999999999999992 0.1519520358231154 11 P35610,O15118,P45880,Q14108,P21796 5 +Dicarboxylic acid transmembrane transporter activity 0.7578420117066687 2.232250809224256 0.0255983910189656 0.9999999999999998 0.1552744507860943 8 P41440,Q9H936,Q9BQT8,Q9UBX3,Q9UJS0,Q02978 6 +Sodium ion transmembrane transporter activity 0.7566842444030688 2.226614153408351 0.02597307222128 1.0 0.1568592090918356 8 Q9H2J7,Q9Y6M7,Q96QD8 3 +Sterol binding 0.6345220762398448 2.2164115820147554 0.026663327203481 1.0 0.1582549456285594 15 Q9BZF1,Q12770,P35610,O15118,P45880,P21796,Q14108,Q9H1P3 8 +L amino acid transmembrane transporter activity 0.7527694843898548 2.207526963443389 0.02727726537744 1.0 0.1590046785878657 8 Q9H936,Q9UJS0,Q9H9B4,P30825,Q96QD8 5 +Prenyltransferase activity 0.8041989007990412 2.198717345465106 0.0278980268159927 1.0 0.1607623795271581 7 P14324,P49356,P53611,P37268,P49354 5 +Phospholipid binding 0.3991713697295024 2.1940684628477656 0.0282304880848431 1.0 0.1613337397575955 91 Q9UM22,Q00169,Q8NFH5,O43292,P45880,Q9BWH2,P50897,P48739,O60313,P21796,Q14108,Q9H4A6,Q9H490,Q92543,Q92643,Q9NZJ7,O14773,P07602,Q9NWW5,Q8WTV0 20 +Sulfotransferase activity 0.95056320400501 2.1732453067347803 0.0297618594850039 1.0 0.1666423144443745 2 Q8NCH0 1 +Molecular carrier activity 0.4788099528533119 2.168703562579887 0.0301051967462717 1.0 0.1678850286294107 35 P40855,Q92973,Q9Y5L0,Q8N4V1,Q9P0I2,Q9NPA0,O43819,P62072,Q8N8Q8,Q15006,Q15070,O15504,Q8TEX9,O75880 14 +Atp transmembrane transporter activity 0.8474310776942384 2.149572280700243 0.0315890629742912 1.0 0.1751320354768112 6 O43808,P12236,P12235,Q86VD7,Q6NUK1 5 +Transition metal ion transmembrane transporter activity 0.894769808957086 2.1487024257101432 0.031657996290096 1.0 0.1751320354768112 5 Q9HD20,P98194,Q8TAD4,Q8N4V1 4 +Azole transmembrane transporter activity 0.9408635794743424 2.1310222868563833 0.0330873061606773 1.0 0.1801564740953416 2 Q9HC21 1 +Phospholipid transporter activity 0.6911272511608911 2.1220089350661873 0.0338369877260991 1.0 0.1828474703294022 11 Q7Z3C6,P48739,Q9Y3B1,Q00169,P08183,Q4KMQ2,Q9H1P3 7 +Vitamin d binding 0.9383604505632082 2.1201031821184317 0.0339973446704449 1.0 0.1828474703294022 2 P04062 1 +Alcohol binding 0.6184465826174158 2.1187645025701585 0.0341103740744654 1.0 0.1828474703294022 15 P35610,O14735,O15118,P45880,P21796,Q14108 6 +Iron ion binding 0.5621891661705675 2.0717755478509807 0.0382863780653688 1.0 0.1990603791894928 20 Q6UW02,Q15800,O75845,O00767,Q16850,P22830,Q32P28 7 +Sphingosine n acyltransferase activity 0.9255319148936252 2.06399854071629 0.0390178547492983 1.0 0.2010979315177163 2 Q96G23 1 +Wide pore channel activity 0.8276462360537089 2.0629803745475135 0.0391144928259332 1.0 0.2010979315177163 6 Q9Y277,P45880,Q96RD7,P21796 4 +Abc type transporter activity 0.7060565917761941 2.046500620542103 0.0407071414750608 1.0 0.207102439498777 9 P28288,P08183,Q9HD20,O75027,Q03519,O14678,P33527 7 +Quaternary ammonium group binding 0.621885434059428 2.0283601601133334 0.0425235030789217 1.0 0.2101522709110627 14 P48739,Q00169,P45880,Q14108,P21796 5 +Intramembrane lipid transporter activity 0.8653674748069637 2.025159339324309 0.0428510053484596 1.0 0.2101522709110627 5 Q96AA3,Q4KMQ2,P08183 3 +O acetyltransferase activity 0.9133291614518196 2.0104121810707913 0.0443875823183581 1.0 0.2135559570849901 2 Q8NF37 1 +Ion gated channel activity 0.9117647058823612 2.0035271314231884 0.0451207384256164 1.0 0.2135559570849901 2 Q9C0H2 1 +Intracellular calcium activated chloride channel activity 0.9117647058823612 2.0035271314231884 0.0451207384256164 1.0 0.2135559570849901 2 Q9C0H2 1 +Atpase coupled transmembrane transporter activity 0.5299601673834847 1.997300164854638 0.0457925854693617 1.0 0.2135559570849901 24 P28288,P23634,P51798,P08183,Q9HD20,P05023,O75027,Q03519,Q15388,O14678,P33527,P98194,P20020,P16615 14 +Folic acid transmembrane transporter activity 0.910200250312901 1.9966387295349692 0.0458644424250138 1.0 0.2135559570849901 2 Q9H2D1 1 +P type transmembrane transporter activity 0.8095323165578642 1.9829985589650756 0.0473675905034485 1.0 0.2156984129004289 6 P20020,P98194,P05023,P16615 4 +Phospholipase d activity 0.9070713391739786 1.9828519434554033 0.0473839699281164 1.0 0.2156984129004289 2 P09601 1 +Proton transporting atp synthase activity rotational mechanism 0.6481584954924878 1.9798086997654871 0.0477250284508541 1.0 0.2156984129004289 12 P00846,O75964,P56385,P24539,P36542 5 +Proton channel activity 0.6481584954924878 1.9798086997654871 0.0477250284508541 1.0 0.2156984129004289 12 P00846,O75964,P56385,P24539,P36542 5 +Porin activity 0.8891671884783854 1.9697386441382327 0.048868331634758 1.0 0.2187213678021693 4 Q9Y277,P45880,P21796 3 +Sulfur compound transmembrane transporter activity 0.752742087120043 1.9590627957210256 0.0501054331583643 1.0 0.2199867112952949 7 Q9UBX3,Q02978,Q8TB61,P17302,Q9HC21,Q70HW3 6 +Adp transmembrane transporter activity 0.8471656749138723 1.9479096062956416 0.0514257801554656 1.0 0.2234726963762741 5 P12236,O43808,Q86VD7,P12235 4 +Amino acid sodium symporter activity 0.8986232790988725 1.945562224322152 0.0517073484023193 1.0 0.2234726963762741 2 Q96QD8 1 +Organic acid sodium symporter activity 0.8986232790988725 1.945562224322152 0.0517073484023193 1.0 0.2234726963762741 2 Q96QD8 1 +Amino acid transmembrane transporter activity 0.657653455104111 1.9415891476981828 0.0521868577037611 1.0 0.2241441745475209 11 Q9H936,Q96NB2,Q9H2J7,Q9UJS0,Q9H9B4,P30825,Q96QD8 7 +3 hydroxyacyl coa dehydratase activity 0.8945556946182791 1.9275745807885387 0.0539080631377637 1.0 0.2266854523049347 2 Q9P035 1 +Solute sodium symporter activity 0.8782527710932759 1.924814209493303 0.0542526056759233 1.0 0.2266854523049347 4 Q9H2J7,Q96QD8 2 +Iron ion transmembrane transporter activity 0.8939299123905011 1.924805363673512 0.0542537127353086 1.0 0.2266854523049347 2 Q8N4V1 1 +Zinc ion transmembrane transporter activity 0.8939299123904989 1.9248053636735032 0.0542537127353097 1.0 0.2266854523049347 2 Q8TAD4 1 +Metallopeptidase activity 0.4471201883238066 1.911742747788868 0.055909198408969 1.0 0.2299106349352983 37 Q6P179,P42892,P09960,Q9UIQ6,Q969V3,Q7L5N1,Q10713,O75844,Q92905,Q7Z2K6,P36551,Q9NZ08,O00487,Q9Y4W6,Q9NQH7 15 +Phospholipid scramblase activity 0.8901752190237793 1.908179626840799 0.0563680038709799 1.0 0.230288589016357 2 Q4KMQ2 1 +Oxidoreductase activity acting on nad p h 0.4560701771979649 1.9021349849069935 0.0571535097942867 1.0 0.2311207720628615 34 O95298,Q7KZN9,O96000,Q13423,Q9UHQ9,Q9Y6M9,Q9P0J0,P03915,O75306,O95139,O95169,O43676,P03886,P16435 14 +Ganglioside binding 0.9652582159624404 1.8696505028945247 0.0615323672039767 1.0 0.2424789877323756 3 Q9UM22,Q9NZJ7 2 +Glycosphingolipid binding 0.9652582159624404 1.8696505028945247 0.0615323672039767 1.0 0.2424789877323756 3 Q9UM22,Q9NZJ7 2 +Oxidoreductase activity acting on a heme group of donors 0.7323823079860476 1.8625044716300003 0.062532015735129 1.0 0.2442988072363938 7 Q7KZN9,P16435,P13073,P00403 4 +Palmitoyltransferase activity 0.8265684803525071 1.859805491483974 0.0629130501578727 1.0 0.2448672636123915 5 P50416,P23786,O15269 3 +Acylglycerol o acyltransferase activity 0.6825256786145946 1.8577207077980176 0.0632086862687084 1.0 0.2448672636123915 8 Q86UL3,Q99943,Q8NF37,Q6UWP7,Q96N66,Q92604 6 +Lysophospholipid acyltransferase activity 0.7257912879975132 1.831040524952988 0.0670944945863691 1.0 0.2542237972957495 7 Q86UL3,Q99943,Q8NF37,Q6UWP7,Q96N66,Q92604 6 +Phosphatidylcholine transfer activity 0.8692115143929915 1.8150376886807176 0.0695181178101358 1.0 0.2591470537234983 2 Q00169 1 +Solute proton antiporter activity 0.8679599499374219 1.8094608960028489 0.070379429940794 1.0 0.2602533465457705 2 O95202 1 +Oxidoreductase activity acting on a sulfur group of donors 0.4940354179613682 1.8063163553921096 0.0708689385400569 1.0 0.2602757650481576 26 Q8NBM8,Q9UHG3,Q96JJ7,Q9Y320,O43396,Q9H3N1 6 +Organic cation transmembrane transporter activity 0.7667981336470934 1.791716635666606 0.073178368366769 1.0 0.2667063974637689 6 O43808,Q70HW3,Q9HC21,Q86VD7 4 +Nadh dehydrogenase activity 0.4909107550785865 1.7816007185946396 0.0748143671771002 1.0 0.2673598702995596 26 O95298,O96000,Q9Y6M9,Q9P0J0,O43676,P03886 6 +Electron transfer activity 0.4046546498816085 1.7734554187365017 0.07615327290087 1.0 0.2714432382007816 57 O95298,Q7KZN9,O96000,Q9Y6M9,Q9Y6N1,O95139,O43676,P03886,Q12797,Q16134,P00403,Q9P0J0,P20674,P13073,P03915,O15460,P21912,P51970,O75306,O95169,Q9UDW1,P16435 22 +Quinone binding 0.7621305267031107 1.7706112420944604 0.0766253711911637 1.0 0.272423877525397 6 Q9Y6N5,Q8N0U8,O75306,P21912 4 +Cdp alcohol phosphatidyltransferase activity 0.8366945788562944 1.7521596612171808 0.0797463577874806 1.0 0.2820695980053342 4 Q9BVG9,Q9Y6K0 2 +Glycolipid mannosyltransferase activity 0.8535669586983712 1.7452079245423442 0.0809486823243075 1.0 0.2841349657278953 2 O75340 1 +C4 dicarboxylate transmembrane transporter activity 0.7548032043734476 1.7373983249689458 0.0823168867155841 1.0 0.2855712544095228 6 Q9H936,Q9UBX3,Q02978,Q9UJS0 4 +Neutral amino acid transmembrane transporter activity 0.7964498106099855 1.7297184103807246 0.0836805977617156 1.0 0.2886041563702064 5 Q96NB2,Q96QD8 2 +Oxidative phosphorylation uncoupler activity 0.8463704630788484 1.713003732727247 0.0867118528803083 1.0 0.2940941102929724 2 P12235 1 +Nucleobase transmembrane transporter activity 0.8463704630788484 1.713003732727247 0.0867118528803083 1.0 0.2940941102929724 2 P12235 1 +Lysophosphatidic acid binding 0.9220657276995236 1.697649114277643 0.0895740071752277 1.0 0.3007224563401511 3 P50897,O14773 2 +17 beta hydroxysteroid dehydrogenase nadpplus activity 0.8429286608260467 1.6975847941806066 0.0895861547448606 1.0 0.3007224563401511 2 Q53GQ0 1 +O palmitoyltransferase activity 0.8423028785982465 1.694780219572336 0.090117121210411 1.0 0.3017723453607711 2 P23786 1 +P type calcium transporter activity 0.8193487789605445 1.6793984097082 0.0930744230265139 1.0 0.3086856763685102 4 P20020,P98194,P16615 3 +Chloride channel inhibitor activity 0.8344806007509377 1.6596949896157107 0.0969758278426482 1.0 0.318486867271469 2 O15400 1 +Solute anion antiporter activity 0.7350733016898008 1.6474902126717972 0.0994573262996196 1.0 0.3220389012020473 6 P41440,P12236,P05141,P12235 4 +Protein prenyltransferase activity 0.8116014744132878 1.646779358494376 0.0996034055808141 1.0 0.3220389012020473 4 P53611,P49356 2 +Phosphoric diester hydrolase activity 0.6293234245823017 1.6464940942013129 0.0996620749923906 1.0 0.3220389012020473 9 P09601,Q8IV08,Q8N2A8 3 +Carbohydrate binding 0.3985407017095813 1.6450578454105482 0.0999578826713871 1.0 0.3222418455350314 47 O75503,Q16706,Q8N4A0,P27824,Q9NPA0,O14735,P35613,Q9UBG0,P49257,P08236,P10253,O15460,P52789,Q32P28,Q10472 15 +Collagen binding 0.6157723602373453 1.639964823239364 0.1010124811883144 1.0 0.3241305370845448 10 Q32P28,Q92791,Q9UBG0,Q53GQ0 4 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.9061032863849656 1.6336517421354444 0.1023319966636369 1.0 0.3270217814168603 3 Q15800,Q14534 2 +Polypeptide n acetylgalactosaminyltransferase activity 0.8074883308050977 1.6294326647568875 0.1032214585445117 1.0 0.3277275356562038 4 Q10472 1 +Acetylgalactosaminyltransferase activity 0.8074883308050977 1.6294326647568875 0.1032214585445117 1.0 0.3277275356562038 4 Q10472 1 +Amyloid beta binding 0.6009547983383551 1.6276875996131246 0.1035911437954735 1.0 0.3277275356562038 11 O00264,Q9Y287,Q8WTV0 3 +Gap junction channel activity 0.8241551939924975 1.6133092075747602 0.1066773471341886 1.0 0.3330356006469139 2 Q96RD7 1 +Gap junction hemi channel activity 0.8241551939924975 1.6133092075747602 0.1066773471341886 1.0 0.3330356006469139 2 Q96RD7 1 +Serine transmembrane transporter activity 0.8023684004363689 1.6078130047849222 0.1078761393548268 1.0 0.3333896031921914 4 Q96NB2,Q96QD8 2 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.45721287104413 1.5979057197025033 0.1100639609659213 1.0 0.3375132106782021 28 O95298,O96000,Q9Y6M9,Q9P0J0,O43676,P03886 6 +Sulfuric ester hydrolase activity 0.8191489361702151 1.590792463724347 0.1116562895569621 1.0 0.3399266402377429 2 O43681 1 +Cyclin dependent protein kinase activity 0.6305922816453726 1.5904648340621987 0.1117300662446367 1.0 0.3399266402377429 8 P11802,P50750,Q00534,O75909,Q00535 5 +Manganese ion transmembrane transporter activity 0.8942097026604067 1.585841165136282 0.1127753449546169 1.0 0.3413876371974478 3 Q9HD20,P98194 2 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.7632199523213712 1.5846083707825278 0.1130553418918518 1.0 0.3413876371974478 5 Q9UHG3 1 +Mannosyltransferase activity 0.7202722130212215 1.579608501723898 0.1141965510721503 1.0 0.3433344133321389 6 Q2TAA5,Q9BT22,Q9BV10,O75340 4 +2 acylglycerol 3 phosphate o acyltransferase activity 0.89170579029733 1.5757634249598933 0.1150803343851785 1.0 0.3452410031555355 3 Q96N66,Q8NF37 2 +Heme transmembrane transporter activity 0.8153942428035255 1.5738947391918168 0.1155117863611494 1.0 0.3457852825486356 2 O15173 1 +Udp glycosyltransferase activity 0.4877686749978935 1.5721458504245638 0.1159167301588635 1.0 0.3462480298265836 21 O43505,Q93063,Q8N4A0,P15291,Q10469,Q16739,Q16880,Q10472 8 +Amide transmembrane transporter activity 0.7586818937024079 1.5646747460116923 0.1176591928382455 1.0 0.3499412122479432 5 P41440,Q9H2D1,Q03519 3 +Phospholipase activity 0.5438373780224333 1.5514926774013489 0.1207836608259298 1.0 0.3569312028253439 14 Q8N2A8,Q9NXE4,P09601,Q8IV08,Q8N2K0 5 +Steroid dehydrogenase activity 0.6649312046459803 1.536047397710497 0.1245267560410228 1.0 0.3630591009808547 7 Q3SXM5,Q53GQ0,Q8NBQ5 3 +Neurotransmitter receptor regulator activity 0.8006883604505608 1.5076419749833951 0.1316461836592743 1.0 0.3777316846489139 2 P49354 1 +Glucuronosyltransferase activity 0.7984981226533142 1.4977667704068127 0.1341938571108902 1.0 0.3810885100294892 2 O43505 1 +Oxidoreductase activity acting on nad p h heme protein as acceptor 0.774097987225538 1.4879467042294756 0.136764949406362 1.0 0.3830769548403622 4 Q7KZN9,P16435 2 +Phosphatidylcholine transporter activity 0.8694835680751171 1.4861638077357189 0.1372357980564873 1.0 0.3830769548403622 3 Q00169,P08183 2 +O methyltransferase activity 0.6093752902678667 1.479362398379092 0.1390434840969794 1.0 0.383455380789387 8 O60725,P21964 2 +Floppase activity 0.8639547428966329 1.463834353715342 0.143239213459593 1.0 0.3904724278066186 3 Q96AA3 1 +Atpase coupled intramembrane lipid transporter activity 0.8639547428966329 1.463834353715342 0.143239213459593 1.0 0.3904724278066186 3 Q96AA3 1 +Ubiquinone binding 0.788485607008786 1.4526055132119242 0.1463333144468468 1.0 0.3976011274655976 2 P21912 1 +Sulfatide binding 0.7645725916494123 1.44739586453405 0.147786083339259 1.0 0.3999768165522411 4 P50897,O14773 2 +Voltage gated chloride channel activity 0.8588419405320815 1.4431748912670996 0.1489712107368452 1.0 0.4018650677004964 3 Q4KMQ2,P51790 2 +Leukotriene c4 synthase activity 0.78566958698375 1.439900194458259 0.1498956380747411 1.0 0.4018650677004964 2 Q99735 1 +Solute cation antiporter activity 0.8579519728844756 1.4395778798979426 0.1499868615591575 1.0 0.4018650677004964 3 O95202 1 +Carbohydrate kinase activity 0.5898460959389147 1.434497947812849 0.1514302143035997 1.0 0.4043011320113482 9 Q9H5K3 1 +Exogenous protein binding 0.4791837553513389 1.431481835432376 0.152292169266234 1.0 0.4058190175244733 18 O15118,Q8WTV0,Q14108,P11279 4 +Gpi anchor binding 0.8541471048513208 1.4241969704135986 0.1543894616562899 1.0 0.408261234169501 3 O43292,Q9H490 2 +Phosphatidylinositol transfer activity 0.8516431924882615 1.4140729581727047 0.1573404820474688 1.0 0.411810149617743 3 P48739,Q00169 2 +Exopeptidase activity 0.4232973070271216 1.4029953078259687 0.16061823814862 1.0 0.4139151401560723 30 Q6P179,P09960,Q9UIQ6,O14773,Q969V3,P10619,P55786,O75844,P42785,Q7Z2K6,P36551,Q9NZ08,P53634,Q9NQH7 14 +Cargo receptor activity 0.5948358860542409 1.4026622063473078 0.1607175923816419 1.0 0.4139151401560723 8 O15260,Q14108,Q08380,Q8WTV0 4 +Phosphatidylinositol phosphate phosphatase activity 0.7217102438598832 1.4013987581438134 0.1610948634361326 1.0 0.4141156061936272 5 Q9NTJ5,Q10713,Q8WUK0 3 +Phospholipid transfer activity 0.6813653692597106 1.3996148440253666 0.1616286864220673 1.0 0.4143828519907149 6 P48739,Q9Y3B1,Q00169 3 +Palmitoyl protein hydrolase activity 0.7202018782152918 1.3947087891367065 0.1631036734057809 1.0 0.4152594530903721 5 P50897 1 +Modified amino acid transmembrane transporter activity 0.752035065748262 1.3939212382169726 0.1633413900803777 1.0 0.4152594530903721 4 P41440,P17302,Q9H2D1 3 +Metalloendopeptidase activity 0.5163943111235683 1.3784881557990478 0.1680526222275655 1.0 0.4220311684745864 14 Q10713,O75844 2 +Acid phosphatase activity 0.7471616684707723 1.37310912342281 0.1697184252078618 1.0 0.4221593202562462 4 Q9NPH0,P11117 2 +Scavenger receptor activity 0.7450277638933336 1.363992172870078 0.1725700291173004 1.0 0.4254266493212594 4 Q14108,Q8WTV0 2 +Peptide antigen binding 0.7125485828540626 1.360736616010957 0.173596938808866 1.0 0.426863637283637 5 Q15392,P04439,Q03519 3 +Oxidoreductase activity acting on the ch ch group of donors 0.418471465604718 1.3601886612371883 0.1737702297835774 1.0 0.426863637283637 30 P21912,Q7KZN9,Q15392,O15254,Q15067,Q9H7Z7,Q8N4Q0,Q14739,Q9NZ01 9 +Lipid transfer activity 0.5858534303879913 1.3550701265744114 0.175395215428084 1.0 0.4269465933986487 8 Q9H1P3,P48739,Q9Y3B1,Q00169 4 +Acidic amino acid transmembrane transporter activity 0.741489089131349 1.3488685736782773 0.177379183944264 1.0 0.4269465933986487 4 Q9H936,Q9UJS0 2 +L aspartate transmembrane transporter activity 0.741489089131349 1.3488685736782773 0.177379183944264 1.0 0.4269465933986487 4 Q9H936,Q9UJS0 2 +Phosphatidylinositol monophosphate phosphatase activity 0.7653316645807345 1.3481364139337524 0.1776145113824037 1.0 0.4269465933986487 2 Q9NTJ5 1 +Long chain fatty acid transporter activity 0.7412918610068333 1.3480254909317928 0.1776501840151543 1.0 0.4269465933986487 4 O14678,O14975 2 +Apolipoprotein binding 0.8338866256606101 1.3422474891480285 0.179515763266866 1.0 0.4269465933986487 3 Q8WTV0 1 +Metalloexopeptidase activity 0.4667125824645706 1.3420798307581143 0.1795701127725855 1.0 0.4269465933986487 18 Q6P179,P09960,Q9UIQ6,Q969V3,O75844,Q7Z2K6,P36551,Q9NZ08,Q9NQH7 9 +Magnesium ion transmembrane transporter activity 0.738885410143996 1.3377373962933252 0.1809820558903581 1.0 0.4286732279482492 4 Q9H0U3,Q9HD23,Q8N4V1 3 +Mannose binding 0.6247853570146055 1.3376332290068125 0.1810160268414877 1.0 0.4286732279482492 7 O75503,P35613 2 +Isopeptidase activity 0.5806615014849503 1.3274956821448078 0.1843447673174296 1.0 0.4335864170068116 8 Q7L5N1,Q92905,O00303,O00487 4 +Acylglycerol lipase activity 0.8272138172641949 1.315251533112656 0.1884253810218261 1.0 0.4401896992452459 3 Q8NCG7 1 +Potassium ion transmembrane transporter activity 0.6992152388949945 1.3014549313519748 0.1931027815596615 1.0 0.4457207380807014 5 P05023 1 +Protease binding 0.4051352837964167 1.2905880945990609 0.1968465464571798 1.0 0.4467013371320771 31 P41440,P14174,P49841,Q96RD7,Q9GZP9,Q9UKV5,P07602,Q9NZJ7,Q6NTF9,P46379 10 +Amino acid cation symporter activity 0.8200312989045269 1.2861981281899455 0.1983739241641045 1.0 0.4467013371320771 3 Q9H2J7,Q96QD8 2 +Abc type xenobiotic transporter activity 0.7515644555694838 1.286072219575491 0.1984178583687912 1.0 0.4467013371320771 2 P08183 1 +Atpase coupled inorganic anion transmembrane transporter activity 0.7515644555694665 1.2860722195754126 0.1984178583688185 1.0 0.4467013371320771 2 P51798 1 +Oligopeptide transmembrane transporter activity 0.7515644555694576 1.286072219575371 0.1984178583688329 1.0 0.4467013371320771 2 P17302 1 +Tripeptide transmembrane transporter activity 0.7515644555694576 1.286072219575371 0.1984178583688329 1.0 0.4467013371320771 2 P17302 1 +Glutathione transmembrane transporter activity 0.7515644555694576 1.286072219575371 0.1984178583688329 1.0 0.4467013371320771 2 P17302 1 +Mitochondrion targeting sequence binding 0.7506257822277806 1.2818438227007023 0.1998974379228111 1.0 0.4487384952332099 2 Q15388 1 +Oligosaccharyl transferase activity 0.693495517813138 1.275994352429906 0.2019575155031194 1.0 0.4499020309048099 5 Q8TCJ2,P46977 2 +Atpase coupled cation transmembrane transporter activity 0.4998090092352665 1.272819341803681 0.2030821560634685 1.0 0.4501523537844235 14 Q9HD20,P05023,P20020,P98194,P16615 5 +Phosphatidylglycerol binding 0.8147398790977214 1.2648005282363968 0.2059428419954279 1.0 0.4520634047786255 3 Q00169 1 +Volume sensitive anion channel activity 0.7213387543609893 1.262664788982333 0.2067096732462281 1.0 0.4520634047786255 4 Q9C0H2,P51790 2 +Ether hydrolase activity 0.6904369113880088 1.2623736402380277 0.206814369731858 1.0 0.4520634047786255 5 P09960 1 +Epoxide hydrolase activity 0.6904369113880088 1.2623736402380277 0.206814369731858 1.0 0.4520634047786255 5 P09960 1 +Long chain acyl coa dehydrogenase activity 0.7200381784037115 1.2570977498096416 0.2087182418782742 1.0 0.4535429533846337 4 Q9NZ01 1 +Flavin adenine dinucleotide binding 0.4066782072194692 1.2550169228851449 0.2094726167252645 1.0 0.4535429533846337 30 Q96HE7,Q16134,Q9Y6N5,Q14534,Q15392,O15254,Q9UHQ9,P49748,Q15067,A1L0T0,Q709F0,P16435 12 +Serine type carboxypeptidase activity 0.6886371611893745 1.2543573262607035 0.2097121559642589 1.0 0.4535429533846337 5 P10619,P42785 2 +Galactosyltransferase activity 0.6500599011415111 1.2535171215600198 0.2100175720116461 1.0 0.4535429533846337 6 Q16880,P15291 2 +Cytokine activity 0.6436432256433116 1.2234790767116606 0.2211488021728653 1.0 0.4698138147543361 6 Q92520,P43490 2 +Nadp retinol dehydrogenase activity 0.6434153214178163 1.2224118034178224 0.2215519378800383 1.0 0.4699483590308175 6 Q9Y394,Q9HBH5,Q8NBN7 3 +G protein alpha subunit binding 0.7097662974045635 1.2131270768811222 0.2250812391810652 1.0 0.4745234051637397 4 P80303 1 +Phosphatidylinositol bisphosphate phosphatase activity 0.7090006200595445 1.2098496012278737 0.2263366092026355 1.0 0.476443729874041 4 Q10713,Q8WUK0 2 +3 hydroxyacyl coa dehydrogenase activity 0.6385163105253133 1.199464217656841 0.2303474902591822 1.0 0.4812244396200136 6 P40939,Q53GQ0 2 +Nucleotidase activity 0.5964547053525474 1.1963245740768045 0.231569922627149 1.0 0.4814341402854895 7 P49902,Q9H857,Q9NX62 3 +L serine transmembrane transporter activity 0.7976184490892204 1.1956317343878229 0.2318403018294548 1.0 0.4814341402854895 3 Q96QD8 1 +Catalytic activity acting on a glycoprotein 0.7961971006790494 1.1898960770734504 0.234087240542661 1.0 0.4852232114565173 3 Q10469 1 +Serine type exopeptidase activity 0.5946159851934889 1.1871289845991695 0.2351767470864953 1.0 0.4854469271949599 7 P10619,O14773,P42785 3 +Procollagen proline dioxygenase activity 0.7028804007513949 1.1836551272420164 0.2365496086511771 1.0 0.48610417349863 4 O15460,Q32P28,P13674 3 +Peptidyl proline dioxygenase activity 0.7028804007513949 1.1836551272420164 0.2365496086511771 1.0 0.48610417349863 4 O15460,Q32P28,P13674 3 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.696858467538437 1.1578898765841734 0.2469089792832264 1.0 0.5006966544702377 4 Q8TCJ2,P46977 2 +Metal dependent deubiquitinase activity 0.5880447742074583 1.1542497154002889 0.2483978056086395 1.0 0.5009483007567161 7 Q7L5N1,Q92905,O00303,O00487 4 +Protein geranylgeranyltransferase activity 0.7798429433724969 1.1240039689590071 0.2610113421971187 1.0 0.5193937931778636 3 P53611 1 +Inorganic anion exchanger activity 0.7124530663329407 1.1105670460706571 0.2667547539737471 1.0 0.5232933684336061 2 Q9Y6M7 1 +Xenobiotic transmembrane transporter activity 0.7752117473406392 1.1053863041903305 0.2689922357171073 1.0 0.5263777281308353 3 P41440 1 +Phosphatidylinositol 4 5 bisphosphate phosphatase activity 0.7707310734856359 1.0873950047389669 0.2768622778511487 1.0 0.5333339044924454 3 Q10713 1 +Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity 0.7707310734856359 1.0873950047389669 0.2768622778511487 1.0 0.5333339044924454 3 Q10713 1 +Phosphatidylinositol phosphate 5 phosphatase activity 0.7707310734856359 1.0873950047389669 0.2768622778511487 1.0 0.5333339044924454 3 Q10713 1 +Calcium ion binding 0.3267240502398452 1.0863376243989464 0.2773296469064119 1.0 0.5333339044924454 84 Q9UM22,O75071,O43852,Q9NWM8,Q96A33,Q6NUK1,Q9BPX6,Q9Y680,Q8NF37,O75340,O43681,O95202,Q14257,Q9BRK5,Q02818,P80303,P16615 17 +Tap binding 0.6788779810634509 1.081057339386246 0.279671608368166 1.0 0.536457467923958 4 P04439,Q03519 2 +Acyl coa binding 0.4935874747183622 1.077098515250951 0.281436256327007 1.0 0.5367724716923296 12 Q00169,P35610,Q9H3P7,Q5T8D3,P40939 5 +Fatty acid derivative binding 0.4935874747183622 1.077098515250951 0.281436256327007 1.0 0.5367724716923296 12 Q00169,P35610,Q9H3P7,Q5T8D3,P40939 5 +Cytoskeleton nuclear membrane anchor activity 0.7660433517072852 1.06859696512343 0.2852513166630741 1.0 0.5390286098010181 3 O94901 1 +Chemokine binding 0.7021276595744621 1.064582675487424 0.287064823086228 1.0 0.5390286098010181 2 P09429 1 +Threonine type peptidase activity 0.5311443079509837 1.062745223901321 0.2878975061132243 1.0 0.5390286098010181 8 P28074,P49721 2 +Threonine type endopeptidase activity 0.5311443079509837 1.062745223901321 0.2878975061132243 1.0 0.5390286098010181 8 P28074,P49721 2 +Solute proton symporter activity 0.758372456963988 1.037896827738546 0.2993180905818007 1.0 0.5526585546159161 3 Q9H936,Q96ES6 2 +Anion cation symporter activity 0.7555254510825711 1.0265236626356775 0.3046448158181869 1.0 0.5565657638352812 3 Q15043 1 +Phosphoric ester hydrolase activity 0.338871001975699 1.025344702446886 0.3052005701292339 1.0 0.5565657638352812 60 P49902,Q8N2A8,Q9NXE4,P09601,Q9NTJ5,Q8IV08,Q9H857,Q10713,P05023,Q8WUK0,P11117,Q9NPH0,Q6Y1H2,Q9NX62 14 +Peptide transmembrane transporter activity 0.7517996870109457 1.0116587058869164 0.3117012660718123 1.0 0.5635069947415902 3 P17302,Q03519 2 +Efflux transmembrane transporter activity 0.7517996870109456 1.0116587058869164 0.3117012660718123 1.0 0.5635069947415902 3 P17302,P08183 2 +Phosphatidylinositol 3 5 bisphosphate phosphatase activity 0.6877346683354126 1.0008490198449418 0.3168998063897636 1.0 0.564735531203435 2 Q8NCE2 1 +Nadplus binding 0.5947272067630975 0.9943068713470612 0.3200734914362502 1.0 0.5672702651391255 6 P40939,Q16836,Q8IXJ6 3 +Modified amino acid binding 0.4035334785959694 0.9336468000447394 0.3504861157585321 1.0 0.6021395007379503 21 Q14108,Q8WTV0,Q9H7Z7,Q99735 4 +Peptide binding 0.3260403273544863 0.9258399882619598 0.3545291423655616 1.0 0.6063941004924117 70 Q9UIQ6,P24390,Q15392,P55786,Q9H7Z7,Q6P179,P40855,Q9NQX7,Q9NZ08,Q8TEX9,P61619,Q03519,P10321,P04439,P42892,Q99735,O14773,O43731,Q15388,O00264,Q08209,Q9Y287,Q8WTV0 23 +Copper ion binding 0.488109243918025 0.9249375554246836 0.354998390041088 1.0 0.6063941004924117 10 Q9Y6N1,O75880,P00403 3 +Transferase activity transferring alkyl or aryl other than methyl groups 0.3923262168380515 0.9172308074152322 0.3590217064806358 1.0 0.6114864779097529 24 P14324,Q86SQ9,Q99735,P49356,P78417,P53611,P37268,P49354 8 +Chemoattractant activity 0.7267605633802852 0.9124106770745706 0.3615525710302127 1.0 0.614053272932562 3 P14174,P26583 2 +Estradiol 17 beta dehydrogenase activity 0.638765431837115 0.9108247594778748 0.3623877145930974 1.0 0.614053272932562 4 Q53GQ0 1 +17 beta hydroxysteroid dehydrogenase nadplus activity 0.638765431837115 0.9108247594778748 0.3623877145930974 1.0 0.614053272932562 4 Q53GQ0 1 +Disulfide oxidoreductase activity 0.3992825917893561 0.9009563091660008 0.3676115501893728 1.0 0.6192530741923297 21 P78417,Q96JJ7,O43819,Q9Y320,O43396,Q9H3N1 6 +Scaffold protein binding 0.3960498570491014 0.897900994824729 0.3692383342620235 1.0 0.6200305114240147 22 Q96RD7,P07602,P17302,Q9NZJ7,P08670 5 +Hydrolase activity acting on ether bonds 0.5349948883869238 0.8889101259479196 0.3740513829825924 1.0 0.6217745035557882 7 P09960 1 +Folic acid binding 0.6329494007276765 0.8863620337037733 0.3754224710364062 1.0 0.6217745035557882 4 P41440,P04818 2 +Syntaxin binding 0.4149772415178014 0.8787459093015886 0.3795390603678741 1.0 0.6271236803927955 16 P49755,Q9BVK6,O60499,O15400 4 +Cytochrome b5 reductase activity acting on nad p h 0.7154828048363391 0.8681605642288709 0.3853064395701913 1.0 0.6325211214436911 3 P16435 1 +Snare binding 0.3717130055449963 0.8635263675095327 0.3878481286347832 1.0 0.6325211214436911 28 P49755,O14653,Q9BVK6,O60499,Q9UNK0,O15400 6 +Transferase activity transferring sulphur containing groups 0.4769623960361506 0.8618842233080505 0.388751231545291 1.0 0.6325211214436911 10 Q8NCH0,Q5VV42,Q7LGA3 3 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.4555257728020685 0.8478731838960438 0.3965086002707776 1.0 0.6391274990378618 12 Q14739,Q8N4Q0,Q15392,Q9NZ01 4 +Amide binding 0.2880540210086132 0.8407048419645905 0.400513307357089 1.0 0.6440812838079699 103 Q9UM22,Q9UIQ6,Q00169,P24390,Q15392,P45880,Q9H7Z7,P40939,P41440,P40855,Q9NQX7,P35610,P21796,Q5T8D3,P61619,Q03519,Q9NZJ7,P42892,Q99735,O14773,Q9Y680,P07602,O00264,Q9Y287,Q8WTV0 25 +Peroxisome targeting sequence binding 0.7057902973395566 0.8304048259346359 0.406309937995416 1.0 0.6503737221940735 3 P40855,P50542 2 +Nedd8 specific protease activity 0.7055702793885168 0.829550990494344 0.406792695977699 1.0 0.6503737221940735 3 Q92905 1 +Myosin v binding 0.6191079475565275 0.828462939734672 0.4074083748018897 1.0 0.6503737221940735 4 P61026 1 +Alcohol dehydrogenase nadpplus activity 0.4869934010372555 0.8262546810401192 0.4086596354563103 1.0 0.6503754612613086 8 Q9Y394,Q9HBH5,Q8NBN7 3 +Oxidoreductase activity acting on single donors with incorporation of molecular oxygen 0.6473717146433031 0.8253442015213845 0.409176203842126 1.0 0.6504490688662762 2 O00625 1 +G protein beta subunit binding 0.7027349973266466 0.818561384065083 0.4130367065043818 1.0 0.6530945514741643 3 P63218 1 +Thiol oxidase activity 0.7026604068857639 0.8182726106578441 0.4132015419666519 1.0 0.6530945514741643 3 Q6ZRP7,Q96HE7 2 +Peptidyl proline 4 dioxygenase activity 0.7026604068857596 0.8182726106578262 0.4132015419666621 1.0 0.6530945514741643 3 O15460,P13674 2 +Procollagen proline 4 dioxygenase activity 0.7026604068857596 0.8182726106578262 0.4132015419666621 1.0 0.6530945514741643 3 O15460,P13674 2 +Antigen binding 0.5194127717575675 0.8115309667725802 0.4170608169729424 1.0 0.6584419062483783 7 Q15392,P04439,Q03519 3 +Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor 0.6429912390488028 0.8066708307219858 0.4198561537911276 1.0 0.6604489685706526 2 Q8IXB1 1 +Acyltransferase activity 0.3195623863114506 0.7853231732396194 0.4322641124048314 1.0 0.6747418368576545 55 P35610,Q9HCL2,P50416,O15269,Q96G23,P27544,Q8NF37,Q86UL3,P23786,O15228,Q96N66,P40939,Q92604,Q96QD8 14 +Ubiquitin specific protease binding 0.4712483622139667 0.7839909597360564 0.4330454148973026 1.0 0.6751993334870006 9 Q6NTF9,Q9UKV5,Q9GZP9 3 +Beta n acetylhexosaminidase activity 0.602237309388641 0.7586295876220587 0.4480741682367757 1.0 0.6862531280968559 4 P17900 1 +Galactosidase activity 0.6292240300375381 0.7485847130546435 0.4541075487741253 1.0 0.6893861031334965 2 P06280 1 +Galactoside binding 0.6292240300375381 0.7485847130546435 0.4541075487741253 1.0 0.6893861031334965 2 P06280 1 +Glutathione peroxidase activity 0.468520277868702 0.7282160813766513 0.4664813231995632 1.0 0.7005531638976932 8 Q99735,Q8TED1 2 +Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor 0.5685504963513841 0.7244577070406522 0.4687847829541383 1.0 0.7016551459151226 5 Q53GQ0,Q8NBQ5 2 +Mhc protein binding 0.4670748152583412 0.720587670250328 0.4711632420631519 1.0 0.7025704878758973 8 P51572 1 +Tau protein kinase activity 0.6770184915143854 0.7201569712959851 0.4714283533975651 1.0 0.7025704878758973 3 P49841 1 +Aldo keto reductase nadp activity 0.4582878210889093 0.7134351223112397 0.4755765459460381 1.0 0.7079896265267716 9 Q9Y394,Q9HBH5,Q8NBN7 3 +Phosphate ion binding 0.5642659090350686 0.7061132384163666 0.4801177196462425 1.0 0.7116857516299607 5 Q8NCH0 1 +Nadph binding 0.4930211789372034 0.681952369817874 0.4952690690587511 1.0 0.7232438457667986 7 Q14739 1 +Glucose binding 0.5270329598667133 0.6819406324535673 0.4952764911467269 1.0 0.7232438457667986 6 P52789 1 +Hexosaminidase activity 0.556944840100531 0.6749414569844476 0.4997129600683097 1.0 0.7251868035408943 5 P17900 1 +Ionotropic glutamate receptor binding 0.5243144376485234 0.6696817949612144 0.5030606593390354 1.0 0.7268974688651474 6 P41440 1 +Sterol transporter activity 0.5230676458958374 0.6640703266831752 0.5066453009105509 1.0 0.7296790074439754 6 Q9BZF1,O15118,Q9H1P3 3 +Mhc class i protein binding 0.4889992970875506 0.6624302363617435 0.5076955311659379 1.0 0.7296790074439754 7 P51572 1 +Pdz domain binding 0.383580843448066 0.6610003004602671 0.5086121208792425 1.0 0.7296790074439754 16 Q9UQB8,P23634,P51790,Q15067,P63218,P20020 6 +Carnitine o acyltransferase activity 0.6602016299634423 0.6572702094163263 0.5110071881519049 1.0 0.7304253532961892 3 P23786 1 +Arachidonate coa ligase activity 0.5525965450648956 0.6565385649059124 0.5114776626247743 1.0 0.7304253532961892 5 O14975,P33121 2 +Long chain fatty acid coa ligase activity 0.5525965450648956 0.6565385649059124 0.5114776626247743 1.0 0.7304253532961892 5 O14975,P33121 2 +Nucleoside diphosphatase activity 0.6569944354930632 0.6454298428558455 0.5186486692423564 1.0 0.7366236623652441 3 Q86VD7 1 +Co smad binding 0.6032540675844785 0.641943952712317 0.5209095746877865 1.0 0.7366236623652441 2 Q93008 1 +Peptidase activator activity involved in apoptotic process 0.6539728920656653 0.6343230894670653 0.5258699909823283 1.0 0.7406091624527089 3 Q9BXK5 1 +Sodium channel regulator activity 0.5462527648727313 0.6298514856397709 0.5287917566664331 1.0 0.7427094511263652 5 Q96PU5 1 +Oligopeptide binding 0.5419341703009184 0.6118005720061981 0.5406697112366441 1.0 0.7505281988983954 5 Q99735 1 +Monosaccharide binding 0.3451664739829903 0.6046754277114957 0.5453946781582699 1.0 0.7505281988983954 27 O75503,P35613,P49257,P52789,Q32P28 5 +Guanylate kinase activity 0.5560425798371983 0.5733375395000978 0.5664161725540493 1.0 0.771964838033577 4 Q14168,O14936,Q00013 3 +Ubiquitin protein transferase activator activity 0.6351843221842841 0.5663934720512821 0.5711263314055024 1.0 0.7774192623999377 3 Q9Y679 1 +Structural constituent of nuclear pore 0.3570854819022366 0.564750418954343 0.5722435351577271 1.0 0.7774192623999377 20 Q7Z3B4,Q9BTX1,Q8NFH5 3 +Glutathione transferase activity 0.4353697699978149 0.5555911035986175 0.5784904145439769 1.0 0.7828299836735029 8 Q99735,P78417 2 +Fatty acid ligase activity 0.4978070175438696 0.5520686256121131 0.5809013365389009 1.0 0.7831263627512631 6 O14975,O95573,O60488,Q6P1M0,P33121 5 +Hydrolase activity acting on glycosyl bonds 0.3280901223230241 0.5454234114268484 0.5854623424294116 1.0 0.7851283951974606 30 O75503,P04062,Q16706,O60502,P08236,P17900,Q9BTY2 7 +Phosphatidylinositol 4 phosphate binding 0.4242355131279242 0.5315079585980856 0.5950668277320288 1.0 0.792086066172662 9 Q9BZF1,Q9NS86,Q9H4A6 3 +Death domain binding 0.6235566674536971 0.5254343621763172 0.5992812713268312 1.0 0.7928102361163104 3 Q07820 1 +Structural constituent of synapse 0.4914290424052446 0.5243817934369768 0.6000130171684743 1.0 0.7928102361163104 6 O15020,P07196 2 +Ribosome binding 0.3052674775730556 0.5166262129717751 0.6054171135531257 1.0 0.7967319308384821 39 Q969V3,P61619,Q96A33,O95202,Q8WWC4,Q9UM00,Q15070,P46379 8 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.5412665676976895 0.5165502099618108 0.6054701802684344 1.0 0.7967319308384821 4 O00767 1 +Kinesin binding 0.3992980824059989 0.5151927566265002 0.606418330131465 1.0 0.7972210556766313 12 O14657,Q9H0B6 2 +Metalloaminopeptidase activity 0.4133654568737233 0.5091412925005415 0.6106531899984411 1.0 0.7973440496242056 10 Q6P179,Q9UIQ6,Q9NQH7,Q9NZ08,P09960 5 +Manganese ion binding 0.3519219681630893 0.5080677171579491 0.6114058541688676 1.0 0.7973440496242056 18 Q8N4A0,Q10469,O14735,Q10472,Q9NQH7 5 +Carbon sulfur lyase activity 0.4831620827406244 0.4889150461226391 0.6249018430025934 1.0 0.8069814770242324 6 P53701 1 +Glucosyltransferase activity 0.4093770133259748 0.4877612405824144 0.6257189683094941 1.0 0.8072475122873417 10 P04062 1 +Sphingolipid transporter activity 0.6109479379933213 0.48207047937413 0.6297558798880114 1.0 0.8109426274535566 3 P08183 1 +Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides 0.4074040237053427 0.477233779963533 0.6331956593597163 1.0 0.8138565026900443 10 Q13510 1 +Nadp binding 0.3426568612566648 0.4427599845353447 0.6579393497850394 1.0 0.8328262355856505 18 P04035,Q13423,P16435,Q14739 4 +L ascorbic acid binding 0.4713160678045222 0.4390124886783632 0.660652487204421 1.0 0.833651815514338 6 Q32P28 1 +Histone deacetylase activity h3 k14 specific 0.5397371714643182 0.4038465260483777 0.6863255808002564 1.0 0.855034572001731 2 Q13547 1 +Hydrolase activity hydrolyzing o glycosyl compounds 0.3298246121757962 0.4022638766106535 0.6874898366347975 1.0 0.855034572001731 23 P04062,P06865,Q16706,O60502,P08236,Q9NUJ1,P10253,P17900,P04066,Q9BTY2,Q9Y223 11 +Peptidase activator activity 0.3853693838891504 0.3940138105551423 0.6935708429738752 1.0 0.8573536209981248 11 O00487,Q9BXK5 2 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.4872855625578687 0.3939912053877646 0.6935875322803648 1.0 0.8573536209981248 5 Q15067,O15254 2 +Poly a specific ribonuclease activity 0.4585251885224043 0.3865048520540662 0.6991228098525246 1.0 0.8632848509200922 6 Q9HBH5,Q9NZN8 2 +Thioredoxin disulfide reductase activity 0.527847309136408 0.3639824734185755 0.7158710972070832 1.0 0.8694646072277147 2 Q16881 1 +Very long chain fatty acid coa ligase activity 0.4974953036944359 0.3583147404833509 0.7201077881562981 1.0 0.8736044482632984 4 O60488,Q6P1M0,O14975 3 +Phosphatidylserine binding 0.3896718570362297 0.3555406155171103 0.7221846230600222 1.0 0.874221999819888 9 Q14108 1 +Fatty acid binding 0.3887128829644901 0.3508359500216609 0.725711425138515 1.0 0.8765579921105382 9 Q15067,O15254 2 +Transmembrane transporter binding 0.3129255904178251 0.3376533618309971 0.735624424428226 1.0 0.8824807170742 27 Q96PU5,P21796,P16615 3 +Trna methyltransferase activity 0.3856012341038582 0.3116374817809183 0.7553160454524763 1.0 0.8955006292558256 8 Q08J23,Q13395,O75648,Q7Z2T5 4 +Microtubule minus end binding 0.3853253156980422 0.3103604513253097 0.756286865488651 1.0 0.8955006292558256 8 Q9H6D7 1 +Calmodulin dependent protein kinase activity 0.4825938202879345 0.30863565199012 0.7575986976146281 1.0 0.8962865686920706 4 Q14012 1 +Nf kappab binding 0.333914822424575 0.276878754843434 0.7818732062696936 1.0 0.911432133570601 15 Q86UE4 1 +Pre mrna intronic binding 0.4288847117794597 0.2714443646741047 0.7860492843125144 1.0 0.9127932224662704 6 Q9BWF3,Q9Y580,Q13148,P14866,P22626 5 +Acyl coa oxidase activity 0.5427927216823234 0.2714405959224277 0.7860521825765918 1.0 0.9127932224662704 3 Q15067 1 +Hormone binding 0.4280088084546939 0.2682048017729457 0.7885416790810216 1.0 0.9135810230655244 6 P42892 1 +N acyltransferase activity 0.3161996461685321 0.2661036701686105 0.7901593684933519 1.0 0.9135810230655244 19 Q96QD8,Q96G23 2 +Aminopeptidase activity 0.3455078767357067 0.2565598778731391 0.7975185512277041 1.0 0.9183748179416442 13 Q6P179,P09960,Q9UIQ6,P55786,Q9NZ08,Q9NQH7 6 +Structural constituent of postsynapse 0.4646408057495568 0.2521800461751128 0.8009019006072657 1.0 0.920737596458727 4 P07196 1 +Cysteine type endopeptidase regulator activity involved in apoptotic process 0.4209888113096211 0.2426107274803429 0.8083069701414416 1.0 0.925404420286104 6 Q9BXK5 1 +Phosphatase activity 0.2707663064278111 0.2380493792628575 0.811842795679572 1.0 0.92564779594637 50 P49902,Q9NTJ5,Q9H857,Q10713,P05023,P11117,Q8WUK0,Q9NPH0,Q6Y1H2,Q9NX62 10 +Phospholipase binding 0.4592865008280719 0.236120455580712 0.8133392013931733 1.0 0.92564779594637 4 P07196 1 +Type i transforming growth factor beta receptor binding 0.4827909887359119 0.2302271525157621 0.8179152638371281 1.0 0.92564779594637 2 Q9UNH7 1 +Long chain fatty acyl coa binding 0.4793491864830893 0.2212450725650758 0.8249016158725067 1.0 0.9288412233061158 2 P22307 1 +Neurotrophin binding 0.4759073842302733 0.2124495146653036 0.8317563601724445 1.0 0.9317666092334864 2 Q99523 1 +Dipeptidyl peptidase activity 0.4492474445222923 0.2070335352680973 0.8359836684809068 1.0 0.9344351591893582 4 P53634,P42785 2 +Acyl coa dehydrogenase activity 0.3573795100906012 0.2041911801381461 0.8382041033946082 1.0 0.934867963705438 9 Q9NZ01 1 +Ephrin receptor binding 0.4097744360902373 0.2031569930431323 0.8390123264018636 1.0 0.9350153484397884 6 P22681,P62993,P18031,Q15375,Q00535 5 +Oxidoreductase activity acting on ch or ch2 groups 0.4699624530663208 0.1977015107995019 0.8432786075996508 1.0 0.9375034680951102 2 P31350 1 +Dna n glycosylase activity 0.4452097683156012 0.195723837915473 0.8448263253008315 1.0 0.9384697252136948 4 P29372,P27695,P23396 3 +Insulin receptor substrate binding 0.4674593241551863 0.1916617843683615 0.8480071426080382 1.0 0.9389235804791486 2 Q05655 1 +Neurotrophin receptor binding 0.4674593241551791 0.1916617843683442 0.8480071426080518 1.0 0.9389235804791486 2 P19174 1 +Neurotrophin trk receptor binding 0.4674593241551791 0.1916617843683442 0.8480071426080518 1.0 0.9389235804791486 2 P19174 1 +Metallochaperone activity 0.5108181390485269 0.189826868560885 0.8494448006244404 1.0 0.9389235804791486 3 O75880 1 +Copper chaperone activity 0.5108181390485269 0.189826868560885 0.8494448006244404 1.0 0.9389235804791486 3 O75880 1 +Histone acetyltransferase binding 0.425663135105349 0.1835837516837045 0.8543400107457058 1.0 0.9429786391550768 5 Q8IXJ6 1 +Acetylglucosaminyltransferase activity 0.4023718532404923 0.1781405036162809 0.8586126334386799 1.0 0.9446788162654688 6 O43505,Q10469 2 +Rna directed dna polymerase activity 0.4599499374217664 0.1741533760584007 0.8617449260329042 1.0 0.9466189298677572 2 Q15185 1 +Telomerase activity 0.4599499374217664 0.1741533760584007 0.8617449260329042 1.0 0.9466189298677572 2 Q15185 1 +Gamma tubulin binding 0.3500558319774659 0.1722207358738113 0.8632639965677722 1.0 0.9472599807716848 9 Q96RT8 1 +Misfolded protein binding 0.3137832217288997 0.1608173442142725 0.8722372643338538 1.0 0.9536001079634148 15 Q6NTF9,P48723,Q9GZP9 3 +Chloride channel regulator activity 0.4901994160829567 0.1440708661809353 0.8854445100999513 1.0 0.9642281554867972 3 O15400 1 +Protein membrane adaptor activity 0.3334258499052357 0.1179499816250114 0.9061072900086704 1.0 0.9805321408098226 10 O75340,O94901 2 +Phosphatidylinositol binding 0.2613674221965833 0.1177614186351276 0.9062567002436794 1.0 0.9805321408098226 55 P48739,Q9H490,Q00169,Q92543,O43292,Q9BWH2,Q92643,Q9H4A6,Q8WTV0 9 +Polysome binding 0.4245932415519297 0.1042157340969291 0.916998147959359 1.0 0.9892421518157516 2 P16989 1 +Nuclear export signal receptor activity 0.3532827730133379 0.0888834424956407 0.9291745424387052 1.0 0.9991429165375242 7 O14980,O15504 2 +Phosphatidylinositol 5 phosphate binding 0.4544600938967237 0.0783074835399408 0.9375834647409074 1.0 1.0 3 O60493,Q9NS86 2 +D1 dopamine receptor binding 0.4544600938967233 0.0783074835399399 0.937583464740908 1.0 1.0 3 Q96QK1,Q15334 2 +Racemase and epimerase activity acting on carbohydrates and derivatives 0.4532081377151873 0.0763187445147199 0.9391655133685748 1.0 1.0 3 Q13630,Q9Y223 2 +Monocarboxylic acid transmembrane transporter activity 0.3802075244428421 0.0474144409259844 0.9621829197704366 1.0 1.0 4 O95563 1 +Carboxypeptidase activity 0.3142445686787978 0.0412537038486997 0.9670936406016049 1.0 1.0 10 P10619,P36551,P42785 3 +Histone serine kinase activity 0.3735919899874727 0.0384496071450262 0.96932920941733 1.0 1.0 2 O14965 1 +Udp glucosyltransferase activity 0.3532854704595869 0.0358466180172556 0.9714046611313458 1.0 1.0 6 Q16739 1 +Lyase activity 0.2518660984770046 0.0348799872039593 0.9721754387994896 1.0 1.0 51 Q99735,P38435,P53701,Q9UG56,Q9P035,Q9H7Z7,P40939,O95470 8 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d153ec3715232c09849b0d8ccf98d7c1ed694192 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 1 adaptor complex binding", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta galactoside cmp alpha 2 3 sialyltransferase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide 1 phosphate binding", "Ceramide 1 phosphate transfer activity", "Ceramide binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Choline transmembrane transporter activity", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromatin insulator sequence binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction channel activity involved in cardiac conduction electrical coupling", "Gap junction channel activity involved in cell communication by electrical coupling", "Gap junction hemi channel activity", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Growth hormone receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosamine synthase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Narrow pore channel activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on metal ions", "Oxidoreductase activity acting on metal ions nad or nadp as acceptor", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidic acid transfer activity", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Sialyltransferase activity", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Store operated calcium channel activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor binding", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG5", "ALKBH5", "AMFR", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "API5", "APMAP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP8", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCCIP", "BCKDHB", "BCL2L13", "BCLAF1", "BCS1L", "BEND3", "BET1", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf35", "C2CD5", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPV", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP5", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT9", "CNP", "COASY", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD7", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHPS", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC19", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM129B", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO21", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCN1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGCX", "GGH", "GHDC", "GIGYF2", "GIPC1", "GJA1", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH1", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS4", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "JAK1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZIC", "MACF1", "MAGT1", "MAIP1", "MAK16", "MALT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED14", "MED16", "MED18", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METTL1", "METTL3", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGAT2", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MPV17", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTDH", "MTFMT", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MUL1", "MUT", "MYBBP1A", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NEMF", "NENF", "NF1", "NFRKB", "NFS1", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NKRF", "NKTR", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMK", "PON2", "POP1", "POR", "PPA1", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB29", "RAB2A", "RAB31", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABAC1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP7", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM47", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "RER1", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNF2", "RNF25", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCA", "RTCB", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP3", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A4", "SLC30A5", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP47", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX19", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "ST3GAL4", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STAU1", "STEAP3", "STIM1", "STIM2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE2", "TAB1", "TAF15", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TEAD1", "TECR", "TEFM", "TELO2", "TERF2IP", "TES", "TEX2", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM10B", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMBIM6", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM201", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRIM13", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIO", "TRIP10", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC21B", "TTC26", "TTC4", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUBGCP5", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS16", "VPS18", "VPS25", "VPS33B", "VPS35", "VPS37B", "VPS4B", "VRK1", "VRK2", "VRK3", "WARS", "WARS2", "WASF2", "WBP11", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", 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1.1555525507377646 0.3935007134599857 0.0002619106881565 0.1367274567490609 0.0990341664275217 0.0001651505356386 3.62520607060078e-06 +Abnormality of the optic nerve 76 263 3.266656556046082 0.0010882561667162 55.26699029126213 243.98300970873785 0.3330545875114519 0.7420961441999799 15.8565039079985 26.975306987282984 0.8419720138567378 0.3446258953426701 6.823334310723731e-07 0.0349791968813944 0.0204732945434617 2.3738184544971942e-06 1.2223500047325129e-08 +Dementia 21 63 3.213952711295895 0.0013092123305045 17.021844660194176 58.19174757281554 0.9978727756866732 0.3214313161707923 5.814027938449679 5.568168011495494 1.793982160512653 0.3770196158976925 1.0544811334180767e-06 0.4854356723902606 0.3755825390431737 0.0001147533965622 2.3026952562873294e-06 +Myoclonic seizure 14 57 3.188327090673637 0.0014309856460454 11.686893203883496 52.98543689320388 0.3944988422537482 0.4078474078990697 4.250245345088794 5.776566450302065 1.383306240067707 0.3629970156021384 0.0004941202618746 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0.3662174808917441 0.7074828170623648 11.504971118984855 18.14139371428998 0.7239337027688777 0.3349741051039537 0.0001329897755556 0.8714052041823894 0.5649596041260996 0.0026523363687025 7.229815944814616e-07 +Abnormal activity of mitochondrial respiratory chain 20 57 2.8630488264489538 0.0041958589984401 14.847087378640778 52.86407766990291 0.7821137838412346 0.382257667326437 7.203923975365814 5.31995427327111 1.5049815702887546 0.3635380021892623 1.8607818020464147e-06 7.472864585443111e-05 2.5687108162745934e-05 2.809657812853656e-07 5.9041483299514474e-08 +Ragged red muscle fibers 9 21 2.8605883021266405 0.0042285577683252 5.233009708737864 17.730582524271846 1.450228655394427 0.2143723456093393 2.356374883616516 2.3878203593303375 1.2019998086948689 0.268108115907532 1.2211621002378708e-05 0.1715759324473242 0.0528695758908991 3.475150315812665e-05 1.12002505888226e-05 +Incoordination 18 71 2.855067961736451 0.0043027620411926 15.859223300970871 69.11650485436893 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0.0057265435683818 0.0015232940214786 0.0002366242380745 0.0002581774489259 +Difficulty walking 20 79 2.7497089061022004 0.0059648227507165 15.580097087378642 75.13106796116504 0.4697839455005359 0.5877808014506588 5.810176207602449 9.191717769736409 0.8615188656802858 0.3499503569147802 0.0001772047104127 0.6437166934391536 0.3279207405402066 0.0052893376956772 0.0013772116096955 +Generalized myoclonic seizure 10 43 2.7396902809308408 0.0061497105588155 9.177184466019416 40.04854368932039 0.4529392195590967 0.4207459458757411 3.6022058822892773 4.354728800706526 1.2466313924241157 0.3493918392140687 0.0065597709750785 0.4436569660453457 0.3202129502459803 0.0006744619263518 0.031720428630349 +Abnormal tissue metabolite concentration 9 17 2.7376364060302385 0.0061882450925283 5.895631067961165 14.650485436893204 0.4799987914691458 0.2340469593783387 2.3926019349714145 2.328417679576543 1.7567023743300048 0.2768423789344761 0.0002047054778288 1.0 0.2709026461704186 0.0078094686864188 0.0001322973571325 +Muscle weakness 84 300 2.7241070336721984 0.0064475607446996 62.08495145631068 284.65776699029124 0.4543336947629458 0.7075817001495509 18.861530859314332 26.81339440066312 0.9176952901579704 0.374241019778978 1.3723987670704914e-06 0.1200699867731065 0.0348088250522519 0.000176278628754 4.745734620795389e-08 +Abnormal brain lactate level by mrs 7 14 2.697664043153865 0.0069827871253427 3.2354368932038833 10.37621359223301 0.6133108438052263 0.4407493118901905 1.9928041796535647 1.6827846873242345 0.9491177620779084 0.3058872918797134 0.0009776198561721 0.0963063052639835 0.1820374447866984 0.0014320459890063 3.757832944814444e-05 +Abnormal csf protein level 6 12 2.697185346000219 0.0069928336509719 4.434466019417476 12.20631067961165 1.1239853500963992 0.2260559983233297 2.11400242863219 2.084072511592451 1.241935948510828 0.248039542652958 0.0006047799608383 0.1715759324473242 0.0528695758908991 0.0023124348467711 0.0023385993552333 +Impaired social interactions 15 52 2.687233279747728 0.0072046616058065 12.00242718446602 47.49029126213592 0.5604537103987376 0.5219910099489533 4.425488172516818 5.269200019661922 1.0091183008466462 0.3500212759055819 0.0005452422537738 0.0001278661716502 0.0004316475760419 0.0008351388883893 3.107724198702484e-05 +Hypertrophic cardiomyopathy 43 113 2.683945591952265 0.0072758945873583 26.796116504854368 107.3495145631068 0.4274787301303976 0.4988726739093555 10.944572821213892 9.196568310864103 1.312724112644841 0.3809066370755179 2.1792792834624488e-05 0.0046678443343074 0.0218378845224151 0.0013045336556116 1.7231600825781628e-06 +Hyperintensity of cerebral white matter on mri 8 21 2.681673310531881 0.0073254958525643 5.844660194174757 19.76456310679612 0.5239793769920946 0.3497882694217939 2.383223245915457 2.1845455756818453 1.3844482033830876 0.3203944687906004 4.1665510572240514e-05 1.0 0.3502020618548794 0.0043649502990921 0.0002465836886751 +Respiratory distress 25 54 2.6615982513673173 0.0077770640099641 12.805825242718448 52.09466019417476 0.6386570898760532 0.4437575130669694 5.288397728288474 5.051988998968333 1.24726945526474 0.3693239953771813 0.0018327141101001 0.4778436071549874 0.1352243419874974 0.0014801972688608 7.431456855205532e-05 +Nephropathy 5 20 2.658984537766353 0.0078376559904953 4.953883495145631 20.679611650485437 0.6460031144846833 0.4125859609731191 2.359716427347698 2.5216098734814283 1.0719980152629416 0.3150102108345451 0.0373936441621624 0.2695684389372801 0.463832032870012 0.0046688430045599 0.0363470309637756 +Hepatic failure 17 52 2.65267064287013 0.0079857750831746 12.25242718446602 48.050970873786405 0.7424989852941342 0.3814651163177168 5.527018274076851 5.448329576476532 1.3577793424610205 0.3539023729255708 3.1428465136783166e-05 0.389715394886943 0.6246554547775687 0.0007782063417519 6.726176549703538e-06 +Brain imaging abnormality 13 42 2.6515295711588265 0.0080128096062936 8.669902912621358 36.84466019417476 0.3330016158803328 0.5991005662160577 3.9088854456823423 5.292433289825244 0.8357355698778169 0.3216729517435908 0.0012556754369772 0.377722993581858 0.2391023108133224 0.0005811578342293 0.0002407839349748 +Horizontal nystagmus 5 23 2.6514817104809185 0.0080139453206173 6.274271844660194 23.053398058252423 1.1086320165192889 0.2915732095622053 2.6115907074401723 2.1860242554539786 1.3408731048130669 0.3129960018850027 0.0165380684646431 1.0 0.0932703984994284 0.0018183768983854 0.0144870993594682 +Vascular skin abnormality 27 113 2.646938361099408 0.0081224156512287 24.946601941747577 116.29611650485435 0.7757412099244599 0.4861695283888829 8.070806982353375 12.284834935174542 1.190653202647226 0.3932244292288712 0.015219771332017 0.5053785480519754 0.4277969769885279 0.0048105461073485 0.0188840951180694 +Abnormal protein glycosylation 10 21 2.6288407488252257 0.0085676472513633 4.992718446601942 17.04854368932039 0.4349711267577257 0.4629072595890348 2.62316887373748 2.93994465563356 1.0108477090998502 0.3020677841214376 0.0003623120908106 0.1594721229818057 0.2915824887707032 0.0106277501006418 5.103650913938958e-06 +Poor eye contact 13 43 2.6233640193985712 0.0087066192594829 9.774271844660197 38.25970873786408 0.6634270903175611 0.4886810186458507 3.917228340019005 4.329065002822378 1.0573021214973186 0.3538640004920722 0.0001063222414334 2.6116330706367664e-05 6.977223838213023e-05 6.740249353507396e-05 9.740232609652992e-06 +Progressive neurologic deterioration 8 21 2.622787331092334 0.0087213693268966 6.75 20.466019417475728 0.5813429756502071 0.2930928839947513 2.6727908035631316 1.300228015706032 1.5791549964390388 0.3142214461904322 0.0001907022646605 0.187449079081247 0.0628860756551618 0.0005352167677164 0.0001709969151957 +Impaired vibratory sensation 9 29 2.6149687301697417 0.0089235624725669 7.536407766990291 29.62621359223301 0.76301203268979 0.4693506811924163 3.6948054205684504 4.667704809367026 0.9514363452495296 0.3439929646326011 0.024203781297757 0.3041527321586795 0.5130324556401258 0.0345747530672156 0.0275555017969666 +Emg neuropathic changes 11 26 2.5919854983227384 0.0095423793856126 6.915048543689321 24.58252427184466 0.5887299592537784 0.4208819793990807 3.046574831105746 2.544837804909062 1.1306803597402475 0.3318248802653038 4.1665510572240514e-05 1.0 0.3502020618548794 0.000686888501954 9.32963770322802e-07 +Optic atrophy 54 200 2.58934968770668 0.0096157392559033 39.97330097087379 184.7135922330097 0.2254846155090266 0.7235761385556879 12.871537267469767 19.604722774296683 0.8047704019364031 0.3342405671672314 0.0001500706443822 0.1942176788124107 0.1670499626424559 0.0011675494662152 4.616135073345861e-06 +Optic neuropathy 12 27 2.588296145607935 0.009645201808617 6.834951456310679 22.009708737864077 0.7947386425872367 0.3403162177193031 3.144874354625535 3.3508299091739815 1.3090216253320466 0.3062511530983536 1.062529684560438e-05 7.841716015172386e-05 0.0010870000966342 1.6783269894967037e-05 2.6805967497323245e-07 +Visual loss 17 54 2.569297663549845 0.0101904882541556 12.189320388349516 49.779126213592235 0.7709512625515322 0.4025114627500821 4.5744204921606055 5.175300864908489 1.242827263568942 0.3662286004483653 0.0025951472263849 0.1723298875515411 0.1855322528907605 0.0044922754835291 0.0005118227083583 +Impaired vibration sensation in the lower limbs 5 14 2.562500101288645 0.0103921557329182 3.5436893203883497 13.5752427184466 0.6952737045250533 0.4242336391370475 2.2993316843683766 2.2069327415111175 1.0005780794846004 0.3215228956981494 0.0157606929495233 0.1715759324473242 0.3116816529125438 0.0140312853386763 0.0102933346763684 +Gait ataxia 20 75 2.559445667175965 0.0104839242577932 14.351941747572816 68.35194174757281 0.6787136514518399 0.4783255809544575 5.256980668043156 6.678826209042067 1.046898326537344 0.3693668840587258 0.0001887769035812 0.5512761203069648 0.4676268126556268 0.0184844040018815 0.0003704016002666 +Abnormal pyramidal sign 36 130 2.5160911197173053 0.0118664499307361 26.563106796116504 122.74271844660194 0.5527646259993448 0.5786409997172964 8.955304229503513 10.063961484693186 0.8713904195746744 0.3609426954901026 0.0005856099354173 0.7727667951590054 0.3259083654951661 0.0151295320543658 0.0001423209426047 +Polyneuropathy 8 22 2.501945688218528 0.0123512871025914 5.689320388349515 18.633495145631063 1.1475655107151586 0.297256939859202 2.871111980426299 2.8359934163787166 1.1251440285742276 0.3008764483611514 0.0034356062671048 0.2220822570468345 0.0874698992517949 0.0014919193154812 0.0007583614663082 +Cherry red spot of the macula 4 9 2.4950880235816486 0.0125925887768909 4.87621359223301 9.031553398058252 0.4125318500531191 0.1346012745180574 1.6566187440434876 0.4477283705000042 2.101542046986786 0.2228325403979826 5.060037785875628e-05 1.0 0.1084298440104649 5.41373461507268e-06 0.0001530581700288 +Hypopigmented skin patches 4 23 2.4936653385707386 0.0126431686024353 6.461165048543689 25.37135922330097 0.4666867513080546 0.4923758628930654 3.0339417473242687 3.9530564673509807 1.0171256647501936 0.3356931601315818 0.1505354185241043 1.0 0.5945251193068862 0.076709375362345 0.3007650800046316 +Cerebellar atrophy 40 139 2.479685589466401 0.0131498277545587 28.725728155339805 134.25728155339806 0.3274524548924733 0.711464704670907 10.30694073827977 14.313813695621468 0.7221325089259758 0.3340728331683771 0.0002563900194537 0.4317447196976769 0.5563154541741528 0.0328102795444381 1.0209397594455308e-05 +Schizophrenia 5 17 2.470542794691047 0.0134908176215775 5.444174757281553 19.50242718446602 0.9817145874838714 0.3473822480141803 2.400301366302062 2.641618717487706 1.084663392230114 0.3211478296747099 0.0043567417361929 1.0 0.0578012116494448 0.0028945217060241 0.0130843956151623 +Biliary tract abnormality 12 28 2.4689069474043928 0.0135526455336314 8.184466019417476 26.4004854368932 1.3038634098573934 0.2674323053300255 3.1080777089644696 2.335313487465734 1.3483489456318312 0.3101233364725878 0.0006819080725987 0.037759654532188 0.0228944934741309 0.0001411774254711 0.0009030765447079 +Periventricular white matter hyperintensities 4 9 2.468487235878473 0.01356854910426 2.978155339805826 8.604368932038835 0.7206271937008832 0.2495118997135797 1.313488091366194 1.3113693798075805 1.4898193087366574 0.2872267653893681 0.0001744219052644 1.0 0.1336663515258769 0.0050923434600555 0.0005143194425855 +Mania 5 15 2.4663586850378665 0.0136494575524064 4.29126213592233 13.815533980582524 0.5633198814967983 0.4160552944360035 2.179476502394243 2.2801276272213657 1.0919629859527038 0.3085705503430486 0.0009840809957548 0.1389130578490434 0.0348321279589049 0.0007982079470274 0.0032151813644344 +Lacticaciduria 4 7 2.4627578275634296 0.0137873004995259 1.674757281553398 4.849514563106796 0.7129753583310345 0.3234768766519366 1.205184467740076 1.4436586333991552 1.2463576287305282 0.29112130721695 0.0001744219052644 0.0022827689145391 0.0086772133501052 0.000366006536683 0.0005143194425855 +Elevated pulmonary artery pressure 12 25 2.4627242659849125 0.0137885910177115 7.422330097087379 24.033980582524272 0.8771466934674594 0.3206437689207037 3.083196929894625 3.78086786662344 1.283632173810104 0.3146045769490745 0.0203119950813603 0.0088678833523326 0.0527430730742316 0.0056146507740375 0.0103895619106309 +Abnormal speech prosody 3 9 2.4584317918352543 0.0139545281474533 1.7184466019417477 7.531553398058253 0.8238611105871386 0.3292070194756458 1.3593793253030109 1.1305443806694235 1.0768574157850217 0.2870822069632543 0.0033751577854829 0.0786913117950012 0.1500965904253892 0.0006143549700213 0.0077153530289291 +Chorea 19 85 2.45360407242442 0.0141432607017026 15.728155339805824 83.02669902912622 0.3692790133375349 0.6638686972138231 5.807919224941267 8.199974294104807 0.7006105038887043 0.3242322398871146 0.0116571474946699 0.2909168632055529 0.0612746755718797 0.002922364893174 0.0114777858111168 +Erythema 9 20 2.4531302580941543 0.0141619046015597 5.512135922330097 21.009708737864077 0.7860124479392929 0.4207309091489555 2.592436403423807 3.539637263054128 0.9160883902281578 0.3036972678357262 0.004235399260567 0.2801168002074996 0.1365892396200844 0.0058282629537454 0.0051385782863233 +Pace of progression 43 171 2.448112949759425 0.0143606629297265 32.4247572815534 161.65533980582524 0.3604186194633252 0.714307837881339 10.960062924546548 14.368677018204007 0.7464776631704437 0.3401326933491765 0.0004285165532121 0.5069131365490065 0.6542864766298802 0.0049484602000353 3.4541700734684064e-05 +Hyperreflexia 68 246 2.441314880423356 0.0146338888764445 48.98300970873787 230.08009708737865 0.1648468619703627 0.7974464047505025 15.891690527909772 23.23185986123223 0.5979112210803894 0.292435294771064 3.256087531452876e-06 0.2981419832557419 0.3063574958420814 0.0001273080927616 1.5768844902610746e-06 +Clumsiness 7 21 2.436485930397798 0.0148307463925139 6.75 20.57766990291262 0.9027704056640264 0.2559090219975202 2.4698423753801175 2.2221930931993956 1.527926415027724 0.282470536898918 0.0004854168565433 1.0 0.3746890061829235 0.0300192966842153 0.0004815310793091 +Hypocholesterolemia 8 10 2.43494009032438 0.0148942554785262 3.2645631067961167 8.048543689320388 1.205673434171466 0.2055905154190861 1.747510449264718 1.0646904903887575 1.232151298114248 0.2464368010987078 4.116742403443895e-06 0.0607401038440192 0.0065261066260236 0.0001991597833083 7.777797134892854e-07 +Abnormal peripheral myelination 10 35 2.431149355658141 0.0150510088054287 7.635922330097087 32.13592233009709 0.6742900044491671 0.4743014543601314 3.568806451618386 4.873244854452022 0.9969709958674222 0.3457305187498817 0.0046654580066481 0.3339036757647639 0.1902313934880583 0.0040838094450097 0.0022524551850594 +Mucosal telangiectasiae 2 8 2.425837071854898 0.0152731252741242 3.2354368932038833 9.689320388349516 0.8501086222195428 0.291727970426265 1.410916714116348 1.5996305775803197 1.2598794700933909 0.2907637890882055 0.0899338349258221 1.0 1.0 0.0291459656321865 0.1506847481690166 +Ankle clonus 4 14 2.425289461158651 0.0152961851643542 3.575242718446602 13.298543689320388 0.6380030192173395 0.4332907678689981 2.0352878876827107 2.085711402355677 0.9658483329689804 0.311402478823635 0.0059643195064532 0.1389130578490434 0.0348321279589049 0.0379489226270714 0.0154010672791248 +Limb ataxia 13 26 2.4236498725573075 0.0153654116304475 6.597087378640777 24.114077669902912 0.989869123864314 0.3154216467413447 2.5039369509835696 2.8496458430585005 1.1323309577692284 0.292147514752726 0.0017114608124302 0.2480154974279715 0.4319828126458854 0.0136344588869589 0.0019208853708131 +Increased cerebral lipofuscin 5 6 2.422412286434561 0.0154178473084882 3.0970873786407767 5.118932038834951 1.0434065701738664 0.1270836154757583 1.1278862704044743 0.4599818751628888 1.7720117842909846 0.2267161680252343 5.557756983342563e-07 0.0470522829573702 0.0038356556834428 6.194004931981708e-05 2.1795177811063544e-06 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19.216019417475728 1.2530133657268057 0.2695837776665858 2.5817154639007844 2.4582801786037667 1.0397164239726309 0.2961148999712332 0.017984491627634 1.0 0.4097170027262437 0.0432632841258681 0.0159325769563511 +Ectopic calcification 18 59 2.402768220153696 0.0162714969805617 13.553398058252426 56.53155339805825 0.5275931647443897 0.4410566614950294 4.995100814049753 5.994858194438004 1.2985638579898735 0.3743313818119885 0.0112148593724692 0.1587221484945262 0.4126058738515607 0.0095980683348544 0.012123502159338 +Spastic gait 6 22 2.395108204601097 0.0166154610807134 6.211165048543689 23.233009708737864 0.1904978612336374 0.625701248220307 3.154065276571727 3.5064541974394436 0.792545244400234 0.3078027861065657 0.006975129893616 0.2480154974279715 0.4319828126458854 0.4184251288308143 0.0227402044332229 +Telangiectasia 5 31 2.3867092697990056 0.0169999290123874 7.37378640776699 35.228155339805824 0.4262114587209472 0.5354451219010867 3.552121235933074 4.829257867279929 0.8971455635118568 0.3342182460970163 0.2971861910361472 0.4354616437047781 0.678425036967832 0.0657790545692253 0.3430832233728522 +Diffuse cerebral atrophy 2 15 2.3809960188709964 0.0172658985497988 4.320388349514563 16.526699029126213 0.5483679808262946 0.4347204443631116 2.152955035100649 2.40585163991881 0.9855175878314706 0.3059596216572743 0.148521892720825 1.0 0.284754537798848 0.051542815486873 0.2375667468636007 +Emg chronic denervation signs 7 15 2.372194171620677 0.0176827952299269 4.550970873786408 13.815533980582524 0.6176194543661773 0.3415909714455588 2.199917039284479 1.6085184210885628 1.2249413291120588 0.2985007469873863 0.0002256493082677 1.0 0.2052107238795277 0.0002291586350063 1.0291992375111868e-05 +Bulbar signs 8 14 2.368134558315672 0.0178780324364005 4.888349514563107 12.016990291262136 1.527818207801298 0.1656113111527082 2.218011046873564 1.4803576942139227 1.2783367300196684 0.2344360472575242 2.050321869767025e-06 0.1430638950507344 0.0369282917904302 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0.019272725348896 8.439320388349515 28.538834951456312 0.8940347945025898 0.342085103264471 3.349932259027002 4.295622811850572 1.233599840087162 0.3264185554851845 0.0211981588561645 0.0145949948181238 0.0817709134109805 0.0147861479784934 0.0139750802028532 +Progressive psychomotor deterioration 4 8 2.339179395722358 0.0193261509766402 3.349514563106796 8.320388349514563 0.5379615244672443 0.2176134167318772 1.5053866894387542 0.6226094824456632 1.5848775742530583 0.2457660654605461 5.060037785875628e-05 1.0 0.1084298440104649 0.0001405335592956 0.0001530581700288 +Fluctuations in consciousness 7 9 2.338613381901791 0.0193554516074196 2.871359223300971 7.104368932038835 1.0899440920546752 0.2545542015295898 1.680977263462837 1.481694234866534 1.1451509420956862 0.2733842157028129 0.0051742294315912 0.0875404472016038 0.1662183776826317 0.000963248429344 0.0001939038931951 +Hypersplenism 3 8 2.3318883508537005 0.0197065654666723 2.7184466019417477 7.970873786407767 0.2142260937784027 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2.212565682747281 0.0269276031571177 4.177184466019417 16.62621359223301 0.8116695621933796 0.4446326391054055 1.7953996864022932 1.7490891479802395 0.7696685494080681 0.3046964378924103 0.0743386516469415 0.2480154974279715 0.1082339466870539 0.053649406266927 0.0639059040821209 +Retinal degeneration 16 61 2.206252114010235 0.0273663522108476 11.890776699029129 56.16747572815534 0.249024006789609 0.518990175786131 4.729602333356375 6.268553853518324 1.1275766261124216 0.3578686327011649 0.0305432267390193 0.603038217660401 0.1071720658755223 0.0063206385106294 0.0103701447977353 +Proximal muscle weakness 26 67 2.2055438539984755 0.0274159540069474 14.951456310679612 61.769417475728154 0.5489884587613049 0.5295429242587456 5.9089016947638 6.961944869050214 0.9537081726509974 0.3546417916471885 0.0051857772959787 1.0 0.7664118675872211 0.1580903162722315 0.0003435449047318 +Kinetic tremor 14 35 2.2052261631503245 0.0274382281361569 7.529126213592233 33.79611650485437 0.3631432849810554 0.5795361764380887 4.109145165819634 3.278672544846394 0.8609997265928164 0.3286830429081078 0.0258171487117352 1.0 0.5176995687514377 0.2776494479137136 0.00098208035012 +Dysdiadochokinesis 8 16 2.200466597514224 0.0277738072999396 4.157766990291262 15.45388349514563 0.6684839389883598 0.4186205101687726 2.0089273726107977 1.5439545323865935 0.9784437725207784 0.3063164957116248 0.1220770094322586 1.0 1.0 0.5428479192551358 0.0662412432855518 +Upper motor neuron dysfunction 86 375 2.200133479957601 0.0277974261230951 70.50485436893204 367.8616504854369 0.0983035353724826 0.8163485718518735 20.780229488630553 35.62483568613682 0.6084591614639696 0.2988339036713152 3.5436538533119063e-05 0.648640921649397 0.3663193800849126 0.0067816530945628 2.898860003209769e-05 +Episodic vomiting 7 11 2.192595180219927 0.0283365586967754 4.179611650485437 11.12378640776699 1.060494846441687 0.2663322982599159 1.9809215871966128 1.7630834730718608 1.1982900451883365 0.2840581402107739 0.029331587130024 0.1389130578490434 0.2567853086841904 0.0062346640440273 0.0154010672791248 +Disproportionate short limb short stature 10 19 2.189467125306923 0.028562905442701 6.587378640776699 19.902912621359224 1.344701363676014 0.2682000023842777 2.8599402401133336 3.1206003999939886 0.9439707190715964 0.2973700803613334 0.0148100428573079 1.0 1.0 0.0814773755217055 0.0161369385533558 +Orthostatic hypotension due to autonomic dysfunction 3 9 2.185664807395945 0.028840137424597 2.8689320388349513 9.026699029126211 0.6690910568198125 0.3153802844238013 1.4405048418053912 0.8105887688186777 1.185865447592776 0.2910194211316744 0.0015547812541629 1.0 0.1253337423142017 0.0041470760753771 0.0036404640413724 +Ventricular hypertrophy 10 38 2.182790427085271 0.0290512469738268 10.04126213592233 36.45873786407767 1.1361758135608295 0.3518404639351837 4.440080726024568 4.153106961798495 1.0569836433105884 0.3376234863759063 0.0009691892751354 0.0761999214167486 0.2285461090114013 0.0794624934300223 0.0058922751399468 +Abnormality of the gallbladder 12 38 2.181117139845456 0.0291747534146638 9.223300970873789 38.0752427184466 0.5027702533780772 0.5379447420549962 3.587145439560844 3.3423828325522775 0.8984096284409542 0.3445277538035425 0.0039700960826603 1.0 0.544786927477571 0.0007832918499315 0.0005285637054372 +Focal t2 hyperintense brainstem lesion 9 20 2.1760698016402644 0.0295500415770098 5.745145631067961 17.558252427184467 0.7787968952644161 0.3563659539921697 2.720936576360794 2.4403574571781053 1.1656572167307155 0.3009968442621839 0.000134607739941 1.3464861962563283e-05 0.0001988861226529 0.0007982079470274 1.1076915443970014e-06 +Abnormally lax or hyperextensible skin 12 44 2.1734648121835707 0.0297453514108572 10.3373786407767 42.60679611650485 0.3474462280446399 0.5687204029624341 3.951804420390705 4.299554326326563 0.9473596696641492 0.3538650259671493 0.0224968008362415 0.4570575797650001 0.118300394527598 0.0842576537166167 0.0830797247222988 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2.6140776699029127 7.645631067961165 0.7865100475706397 0.3005269589284746 1.5309416715650457 0.8593604190958345 1.1613991531101726 0.2793709321885783 0.0620387079127585 1.0 0.2052107238795277 0.0193169154759243 0.1068437246174296 +Involuntary movements 80 336 2.150032600588646 0.0315526361632783 64.20631067961165 324.16747572815535 0.1561786112826782 0.7846530873453128 17.968922983446493 30.75077724863295 0.6578098650819268 0.313999179195925 3.604006608095267e-05 0.3687204132269234 0.0502689430187445 0.0003889680839019 2.2290157260530232e-06 +Areflexia 37 95 2.1461821417454567 0.0318584497863096 20.16990291262136 86.04126213592232 0.3697353101404192 0.6748143831754785 7.040125425728686 10.82543509559568 0.6914116832707108 0.3259405906435058 0.004826935020539 1.0 0.6254673162270674 0.1656706784113457 0.0004149672066052 +Memory impairment 12 41 2.139396024383143 0.0324036086534513 9.20631067961165 37.271844660194176 0.6455055455031676 0.5315679983039603 3.950378988895289 4.419054449573657 0.8352402457141732 0.3415020574881957 0.0133288800762842 0.3807425591661329 0.242627214008706 0.0323705971244195 0.0208266866410338 +Knee flexion contracture 8 26 2.134271770494468 0.0328205406818198 6.37621359223301 26.20631067961165 0.4874196163722039 0.571576100604669 2.548884628142718 2.167424085317431 0.796597726565237 0.3234136220769761 0.0005372587149445 1.0 1.0 0.0166327696461577 0.0027292579963932 +Disproportionate short stature 10 23 2.126263012829319 0.0334813659450803 8.58252427184466 24.70145631067961 1.4449047806081987 0.2464238748623315 3.3320283680556178 3.793287097673045 1.0910515137563812 0.2952991105687103 0.0203119950813603 1.0 0.5744906956895812 0.0637395822669413 0.027380165942545 +Personality changes 4 17 2.121796514153749 0.0338548295045282 4.235436893203883 16.20873786407767 0.716641708966708 0.4361664780008399 2.2513009299259603 2.2727002372019856 0.9467269936740988 0.3182188186141179 0.055974397409098 0.1675604235637086 0.3050454458143302 0.0128293519549119 0.0345960499792071 +Choreoathetosis 4 33 2.121743157048681 0.0338593123687502 8.220873786407767 31.393203883495147 -0.0890561861383339 0.6132878976765619 4.807685111329692 3.74629298031452 0.849713593166173 0.3070869349684345 0.2113762162495472 0.3306605597140526 0.1867915963698719 0.0499487852123864 0.3721082210217046 +Generalized onset seizure 26 104 2.1126138823905167 0.0346338295341837 19.41747572815534 101.3980582524272 0.2319930086793499 0.5996604289677846 7.392628540299301 10.211443994980636 0.9212672819752036 0.3453115940524636 0.013620505282542 0.7270359107717075 0.247109912793677 0.0051214877051137 0.0095581214707342 +Abnormality of lysosomal metabolism 4 6 2.10406463094249 0.035372809592985 2.0509708737864076 4.776699029126213 0.6001877831871685 0.2139165882109918 1.054267347463803 0.832379194243084 1.5763659100060583 0.2506311014666729 0.0002279404819355 1.0 0.0824659877424542 0.0010464818333657 2.748807069516661e-05 +Tetraparesis 6 37 2.101517549539097 0.0355955590932077 7.587378640776699 35.63592233009709 0.2185556182972484 0.6062059087017716 4.06496228410477 3.1735360318458175 0.8238612160205229 0.3182737840492536 0.0460964721555363 1.0 0.1971367302696896 0.004652372899716 0.1208033257987883 +Spastic tetraparesis 5 25 2.1010793951016837 0.0356339973211934 5.230582524271845 24.473300970873787 0.2090726806611247 0.5676748710859181 3.263171465029081 2.380496353704214 0.915257703448056 0.3194790998285025 0.0151739236366123 1.0 0.3982623430868609 0.0016490180911792 0.0413001469897655 +Bilateral sensorineural hearing impairment 8 29 2.100370679959572 0.0356962461392895 6.381067961165049 24.424757281553397 0.7447297270654177 0.4543730451773109 2.694462286764978 2.8252792093863337 0.8997615483176746 0.3241521581359238 0.0042607650148558 0.2295798469686227 0.0932703984994284 0.0094868932073139 0.0040774539205705 +Paroxysmal involuntary eye movements 9 21 2.099387842972889 0.0357827254845355 5.910194174757281 19.138349514563107 0.6558846901538902 0.3953776148518428 2.72692311425057 2.547182946947119 1.094018237549431 0.2977191822416544 0.0001666980232874 1.5334158934995565e-05 0.0002256496047817 0.0009276346440678 1.5423305399170309e-06 +Abnormal gallbladder morphology 9 30 2.0991356524860123 0.0358049443875989 7.478155339805825 31.075242718446603 0.4272058322069254 0.5481313499841369 3.2037612142007585 2.976716880674025 0.8468189606834012 0.3256570196959197 0.0046352895150921 1.0 0.4840762718710899 0.0013192316861744 0.0056641713323413 +Widened cerebral subarachnoid space 3 5 2.0821838194110645 0.0373256826496453 1.0412621359223302 3.254854368932039 0.777955775294041 0.3679674481239524 0.873418881714406 0.9060748207147904 1.1521650723162982 0.3128617037317782 0.0002279404819355 0.0424464003246627 0.0824659877424542 0.0010464818333657 0.0005558041127602 +Young adult onset 6 12 2.077208325994549 0.0377823357505329 3.936893203883495 11.097087378640778 0.9326277418903632 0.2839315553797075 1.7793033594374144 1.2484130750505644 1.1998221427979727 0.2831359733121 0.0068516550010284 1.0 0.2638774705145789 0.0411512789917762 0.0037990009847076 +Abnormal reflex 95 371 2.0752583109620697 0.0379626009570384 73.24029126213593 348.21844660194176 0.0357439482559977 0.8193094696304006 22.373441864988948 35.46789673152087 0.5442577949043176 0.2705624962629831 4.291074812616916e-05 0.617017653985732 0.601452072854493 0.0010509644124732 1.0257956657535409e-06 +Macrovesicular hepatic steatosis 7 9 2.074087261511765 0.0380712074119271 2.466019417475728 6.87621359223301 0.939079379807938 0.3067324443022926 1.4701927354039712 1.258646689249585 1.014263353538022 0.2700508944960845 0.0054519195422099 0.0470522829573702 0.0912026913027489 0.0229613270793894 5.279662360650864e-05 +Atlantoaxial abnormality 2 5 2.0707935492834664 0.0383780933263748 1.4660194174757282 3.849514563106796 1.0726212659562588 0.2746386395490074 0.9171032274068438 1.0957440869823794 1.0965015067037602 0.2693675199183011 0.0054519195422099 1.0 0.0912026913027489 0.0014684283121974 0.0103919051808895 +Neuronal loss in central nervous system 5 14 2.0638401610616564 0.0390328738404521 4.087378640776699 12.526699029126211 0.982175765643533 0.2959736314179056 1.731247914675439 1.993135251988059 1.1236470294677874 0.2967990988512021 0.0263164558235643 1.0 0.2496255286594674 0.0348798008289802 0.0134356018089951 +Abnormal lung lobation 2 13 2.061930123898469 0.0392143890709382 3.266990291262136 13.402912621359222 0.8057824047211188 0.4237226990881645 1.8647412350490211 1.7258152040640289 0.8098324555644494 0.3032019531807652 0.1306895040375719 1.0 0.2709026461704186 0.0444854600227105 0.0726348754294577 +Dermal atrophy 5 28 2.0604059919693225 0.0393597445585021 5.320388349514563 26.895631067961165 0.7910895542770026 0.4477466139002859 2.6272049167180267 2.645986214694848 0.8422228280317593 0.3177571120785681 0.0600280047040733 0.297366720714231 0.1529837701743424 0.0994768290011166 0.1397062733636897 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8.720873786407767 38.65291262135922 0.1511522539065132 0.7115287253554565 3.7787411492970135 4.922547318123117 0.6118796638334504 0.2798918753737032 0.0571599291171704 0.4101596343015291 0.6491947533061961 0.0481335997642302 0.0801486714597216 +Mitochondrial inheritance 5 6 2.049406545203796 0.0404223777643655 1.577669902912621 4.247572815533981 0.9928856357718184 0.2727497270810077 1.119676794457053 1.2095369137272214 1.2442723588935711 0.2811589341958167 0.0020567301082413 0.0697581245313758 0.1336663515258769 0.000366006536683 0.0005143194425855 +Phenotypic variability 29 109 2.0458937557018566 0.0407668248394266 22.339805825242717 99.4368932038835 0.8464119152872666 0.5170730885331468 8.500203764614474 8.607030207254683 1.0360918895927824 0.3938137781932724 0.0643255220304441 0.7402160849379072 0.4908784941016936 0.0070348618551996 0.0142675322277904 +Capillary hemangioma 4 7 2.0428678392844057 0.0410655227440699 2.533980582524272 7.133495145631068 1.1471796350867234 0.2683759543048971 1.4112277515033682 1.3471092449900268 0.9767941621718578 0.2786452679412407 0.1306895040375719 1.0 0.2709026461704186 0.1887844423268079 0.0198874102408346 +Abnormal metabolism 16 54 2.039436455355549 0.0414064871509114 10.526699029126211 47.99271844660194 0.0080245789706845 0.7383718142779401 5.174786312055402 5.321001200441192 0.6064611886602139 0.2734583373792854 0.0059388115994507 0.0875356389619515 0.2567478928672068 0.1033455447275472 0.0004072680327928 +Abnormal brainstem mri signal intensity 9 23 2.028774257808017 0.0424812883945056 6.252427184466019 20.32281553398058 0.9466857218441096 0.334812084954676 2.9078682900486936 2.582646312540884 1.1241621585657078 0.2967087697298931 0.0004323686514419 2.767020592246164e-05 0.0003996291666218 0.001820540651884 6.695517627710681e-06 +Segmental peripheral demyelination remyelination 4 7 2.028241012507738 0.0425356560068512 1.6601941747572817 4.737864077669903 1.1231406516527276 0.2457358043386077 1.1021021225411718 1.375663406058269 1.1869683790120098 0.2709829643602553 0.0008170986671625 0.0561990347849709 0.1084298440104649 0.0025975272437437 0.0019443402252438 +Mitochondrial respiratory chain defects 5 7 2.0240534834971227 0.042964649042517 1.8033980582524272 5.177184466019417 1.0048180638921334 0.285673153216041 1.1353491002390874 1.0681459460620504 1.0953831291184488 0.2879410254685434 0.0214626028283106 0.0742352733278267 0.1419203898220533 0.0061570039439817 0.0007186517412764 +Abnormal epiphyseal ossification 8 18 2.018826250726231 0.0435052816249823 6.451456310679611 16.274271844660195 1.1227269321938518 0.3276999393402902 3.140724178369711 2.4155680760400804 1.043634905787503 0.3148370578580727 0.0062137664371764 1.0 0.3439334989552355 0.0039562767661884 0.0047344797567726 +Abnormality of glycolipid metabolism 3 7 2.016955507800531 0.0437001566025783 3.83495145631068 7.228155339805825 0.3163887308740252 0.1681411938672545 1.311614193945771 0.5964160722258837 1.870431483654663 0.2292796295173983 0.0003684617786793 1.0 0.0912026913027489 0.0014684283121974 0.0008911424388636 +Abnormal auditory evoked potentials 3 7 2.016498041087604 0.0437479228541541 2.837378640776699 8.45388349514563 0.8113355275163785 0.2966376606156203 1.5470802196866602 1.3128600166506037 1.1722229382642326 0.2813987538538041 0.176883840010458 1.0 0.1741653971767485 0.0828772873031817 0.069181328144546 +Microcytic anemia 5 9 2.013404510939848 0.0440720914395018 2.441747572815534 8.526699029126213 0.6645628317552182 0.3838242289014166 1.6704179043327654 1.438636684975842 1.0496853438983738 0.3012783873714112 0.2191355408597602 1.0 0.1975594178204269 0.4301270919610729 0.0967889104749245 +Varicose veins 1 5 2.00833956872242 0.0446072198452203 1.449029126213592 5.400485436893204 0.5039016792864417 0.4504533293589469 1.1657840518133464 1.015558460972087 0.9378322272027768 0.2968584263412278 0.204933269580831 1.0 1.0 0.097689242801984 0.2873869680451539 +Venous insufficiency 1 5 2.00833956872242 0.0446072198452203 1.5631067961165048 5.660194174757281 0.5118223066706069 0.4552197834062824 1.2379116686073368 1.1621322724229128 0.9295972263181714 0.3009174121939262 0.2908287375332745 1.0 1.0 0.1457934990596532 0.3943429961753201 +Unexplained fevers 1 5 2.0062724186662937 0.0448271910529181 1.5388349514563109 5.621359223300971 0.7467355824508212 0.3321409792965325 1.0149114466807625 0.7710351742240161 1.1275544850735062 0.2907731941603199 0.0747757989798899 1.0 0.1084298440104649 0.032628233248221 0.1114297880404725 +Abnormal circulating protein concentration 57 156 2.005768544273261 0.0448809481990868 32.71116504854369 148.9271844660194 0.3300298217826257 0.7446264209348606 9.601606439314072 14.083300681736008 0.6353139637633994 0.3197600075827534 0.0239806440486839 0.5601360273234894 0.3076966356946233 0.2253043481150884 0.0122151407282881 +Occipital meningocele 1 5 2.005156096149392 0.0449463620078143 1.614077669902913 5.305825242718447 0.4694090704141183 0.5064024976559787 1.173781489144657 0.9895890333349424 0.8607405237454151 0.3006870950401374 0.0638868358124415 1.0 1.0 0.0276231155809849 0.0958131716431155 +Spasticity 72 309 2.0012964900913235 0.0453604477778928 58.66747572815534 304.06067961165047 0.1220030100697469 0.7993443297439564 17.104720589462595 29.296586956591348 0.6545319764403259 0.3129506175311353 4.79811496407083e-05 0.4564204486771898 0.2427767201786941 0.001096564770299 1.7040203108853544e-05 +Retinal dystrophy 20 61 1.999022174469756 0.0456059546839076 12.434466019417476 54.21116504854369 0.2005252410651455 0.6758492800321638 4.7575261230971835 6.937765763435153 0.737701572424903 0.3115763272161692 0.0429801219762462 0.6574721749282701 0.622987427801012 0.0852463545440613 0.0664394655400724 +Abnormal nervous system electrophysiology 45 187 1.996382799438562 0.045892271612665 36.47572815533981 182.9004854368932 0.3300418821967583 0.7178291062368368 12.295191782751669 18.7740085709633 0.7539598524877194 0.3420878538095431 0.0174761561373153 0.6797679462018151 0.307886367063846 0.0236788191513679 0.0018053729616141 +Increased serum lactate 34 116 1.99637659303827 0.0458929466574558 28.99514563106796 103.9126213592233 0.2156320103365802 0.4835633979758786 13.01418105275692 9.239117761559864 1.4606133548257267 0.3784654233889921 6.837437096793606e-07 0.0093664892176293 0.0012778772131135 8.886216188062317e-07 7.748852071515229e-10 +Migraine 12 27 1.9924641450874403 0.0463201554092027 5.716019417475728 23.116504854368937 0.5491247833805577 0.5283138672374208 2.829188308518868 3.093372090575774 0.8241882772707269 0.3182507609453459 0.0226611051563601 0.3007677906227077 0.5083206499791918 0.2645177746775517 0.0256551863783072 +Abnormality of corneal stroma 3 13 1.9901307621226645 0.0465765329060667 4.733009708737864 13.131067961165048 0.6716440045814968 0.2233795964932449 1.7589100966397004 2.506749302052849 1.61853564814875 0.2527544669587041 0.1884978639224942 1.0 1.0 0.053649406266927 0.3174981317995778 +Redundant skin 8 27 1.9884851223811968 0.0467580628144645 6.371359223300971 25.308252427184467 0.2787132609503967 0.5601560778174463 2.8980165793624426 2.8171854463618717 0.9126105182113172 0.3237356069203403 0.0108001996375944 0.2660187864050092 0.1237843690563061 0.2004801313125411 0.0337771362759376 +Sensory neuropathy 10 39 1.985348809498386 0.0471056770994393 9.17233009708738 33.75485436893204 0.684837850359792 0.4572087500958895 3.983815730493952 4.346698415431409 1.0448123352909229 0.3439679266340525 0.0021499933736848 0.3041527321586795 0.5130324556401258 0.0345747530672156 0.0008771815788948 +Hypointensity of cerebral white matter on mri 1 7 1.98393984839838 0.047262545970081 1.4393203883495145 6.449029126213592 0.4152087503677575 0.4308727744228336 1.2842237367722065 0.7942903220211851 0.9636604335235156 0.2761758278792059 0.0638868358124415 1.0 0.0998570540504815 0.0276231155809849 0.0958131716431155 +Muscle spasm 18 62 1.9812071619278415 0.0475680463942267 12.46116504854369 57.41990291262136 0.5782385518256496 0.5270109112328661 4.685854213547734 5.0957713280196595 0.8793305042203639 0.3427211662973412 6.140949437015803e-05 0.4463627535095094 0.3237138230889217 0.0281363706052967 0.0002446504366023 +Retinal telangiectasia 3 6 1.9794978781825543 0.0477599782997792 1.3106796116504855 5.007281553398058 0.8088648966265131 0.3483026313211161 1.0430456357811864 1.087191709833904 1.1553193033520868 0.3106693264231038 0.0341372510921193 0.0875404472016038 0.1662183776826317 0.0101015401572799 0.0116417512175889 +Ventricular arrhythmia 16 41 1.9726579558068515 0.0485345451769327 10.0 36.96601941747573 1.0415384316890377 0.3677574027458479 3.8522468541414527 4.8022861343455805 1.0152201826292362 0.3231502492090489 0.0051724904309126 0.3867386931517215 0.621013884389783 0.0352078323408286 0.0092689304184675 +Raynaud phenomenon 1 6 1.9682885639343295 0.0490348450303022 1.5145631067961165 6.242718446601942 0.9919476180863708 0.3155318164932874 1.0668352405519568 0.7236104114257896 0.8937818768405142 0.2739634297108673 0.1104430428419075 0.0697581245313758 0.1336663515258769 0.0495157384890535 0.1615113588580296 +Spastic paraparesis 5 21 1.9635387746950228 0.0495836036038859 5.478155339805825 20.550970873786408 0.6522343609765672 0.5124278683317688 2.4725696108954978 1.913118744158018 0.8986801667257259 0.3474119612866397 0.0062137664371764 0.1913705796369965 0.3439334989552355 0.0039562767661884 0.0182027983739356 +Bilateral tonic clonic seizure 14 91 1.9626892780141283 0.0496822897355824 16.54126213592233 83.87864077669903 -0.1036545284961206 0.6620244011720979 6.822346659397593 8.994865315056538 0.7668565661638337 0.3104656168106364 0.0147199309399112 0.6723257233582134 0.6448590582020931 0.0036692663388399 0.0875933867797739 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..35e93ba154818f27e9585620bd888f48b1f78ab6 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 4582, + "title": "Average number of proteins per term", + "value": 24.18092536010476 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..745f00e13b340807bba445e8de313da046e3414b --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7a7b87ed062c7871aec0c8f4bf4529725f37edc3 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1643 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cognitive impairment 0.4327030560387535 3.6608585284390105 0.0002513715348342 0.6839734847123665 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Q9BUK6,O96000,P07196,Q8WWV3,O15020,O14949,O43676,P03886,Q86Y39,O75352,O75298,P50897,Q8WWI5,Q5XKP0,Q9C0E8,P56589,P17302,Q9Y276,Q86VD7,Q9NZ08,Q9Y4W6,Q9H936,Q86SQ9,O14653,O75027,P18887,Q9NZJ7,P00846,O14773,P21912,P04062,Q10713,P07602,Q13510,Q9H6K4,Q9H3H5,Q99720,Q7KZN9,Q9Y6M9,Q5H8A4,O95470,Q96AA3,P40855,Q7RTS9,P39210,P00403,Q6P4A7,Q9P0J0,Q14108,P03915,Q6DKK2,Q9Y287,Q9NWW5,Q01105,Q8NBM4,Q9Y487,O43292,Q15067,P40939,Q96IX5,P41440,O75503,Q8IV08,Q9NR77,P12235,O15118,O75340,Q5T8D3,Q8N0X7,O43681,Q9NVI7,O75381,O96008,Q9NQZ5,Q9NX14,Q96CU9,Q9BPX6,Q9BUB7,O95202,Q8N2K0,Q8NBU5,Q9NPL8,P35610,O60313,P29084,Q9Y375,Q9UBB4,Q8NI60,Q92643,Q2TAA5,O15460,O75306,O43819,P35637,Q9Y4P3 95 +Optic disc pallor 0.5618542704068863 3.3724525214611027 0.0007450193025071 0.9671219725897456 0.0714730545561285 56 Q96CU9,Q9H3H5,O95298,O96000,Q8WWV3,Q9Y6M9,O43676,P03886,Q86Y39,Q9NPL8,O60313,Q9H061,Q9Y375,P51798,Q96S66,Q9UG56,Q9H0B6,P00846,Q10713,O75306,Q9H6K4,Q9NX14,Q9Y287 23 +Sensorimotor neuropathy 0.6281693002759386 3.3489320879813675 0.0008112367751265 0.975731970136548 0.0714730545561285 34 P41440,Q9Y2R0,P39210,P00846,P00403,P07196,O60313,Q9NR77,P05023,P03915,P07602,Q9NZJ7,Q8N2K0,P40939,P03886,Q9Y4W6 16 +Functional motor deficit 0.4335290044055552 3.330566765024618 0.0008666937652201 0.9811814601035764 0.0714730545561285 153 Q9Y2R0,Q9H3H5,Q9BUK6,Q99720,P07196,O43292,Q9BPX6,Q15067,Q9HC21,P40939,P03886,O75298,Q15041,Q7RTS9,P00403,P13473,Q9NR77,P12235,O75340,Q9Y276,Q9H2D1,Q9H5K3,Q9NSD9,Q8N0X7,O14653,Q9NWM8,P03915,O43681,Q8NI60,P23786,Q9NZJ7,Q3ZAQ7,Q9H0B6,P00846,O14773,P21912,P04062,P53701,Q53H12,O43819,P07602,P51530,P35637,Q13510,Q9NX14 45 +Abnormal circulating lipid concentration 0.5199735815101185 3.3300437422662053 0.0008683234183679 0.9813215772408124 0.0714730545561285 77 O75431,P50402,Q9BTV4,Q15904,Q15392,Q9BV10,O75648,P40939,Q14739,O95470,P40855,Q15800,Q8N511,O75844,P56589,Q16836,Q15056,O75845,P49748,P22830,Q9Y6B6,P23786,Q9NZJ7,Q9NVI7,P37268,P31751,O96011,O75381,Q9UBM7,P07602,Q8NFG4,Q9Y4P3,P50416,P49257,O75880 35 +Muscle abnormality related to mitochondrial dysfunction 0.5974519835057264 3.318127992698797 0.0009062294774555 0.9843020648000826 0.0714730545561285 40 Q96CU9,Q9Y2R0,O96000,Q9Y6M9,O43676,O75648,P03886,Q86Y39,Q9NPL8,P00403,O60313,P12235,Q9UBX3,Q9Y375,P03915,P00846,Q53H12,O75306,P51530,Q9NX14 20 +Frequent falls 0.5928077526465014 3.310402773037332 0.0009316181090033 0.9860274948514534 0.0714730545561285 41 Q7RTS9,Q9H3H5,P00846,P21912,P04062,Q9NR77,P12235,O75340,P07602,Q9NZJ7,Q13510,P40939 12 +Abnormality of the cerebrospinal fluid 0.4366235327484319 3.303080958760926 0.0009562877501037 0.9875222334653836 0.0714730545561285 147 Q96CU9,Q7KZN9,O96000,Q15392,Q9Y6M9,Q8TAA9,O95202,Q9HC21,O43676,P03886,Q86Y39,P40855,Q9NPL8,P39210,P00403,Q9NR77,Q9P0J0,Q9H5K3,Q9Y375,Q9H490,P51798,P13073,P03915,O43681,Q8NI60,P23786,Q9NZJ7,Q6NUK1,Q9NWS8,P00846,Q9UBM7,P04062,P53701,Q10713,P15291,O75306,P21964,O43819,P07602,P08236,Q9NX14,Q96J42,P16435 43 +Abnormality of the optic nerve 0.4010642013663386 3.266656556046082 0.0010882561667162 0.9931882414435456 0.0714730545561285 263 O43505,P49902,Q9H3H5,Q96CU9,Q9BUK6,O95298,Q7KZN9,O96000,P07196,Q8NBM4,O43292,Q9BPX6,Q8WWV3,Q9Y6M9,Q15067,O95202,Q9HC21,O43676,O75648,Q8N2K0,P03886,Q86Y39,O75352,Q5H8A4,Q7LGA3,P50897,P40855,Q8WWI5,P41440,Q5XKP0,Q13144,Q9NPL8,P00403,P51572,O60313,Q3ZCQ8,Q9P0J0,P56589,P17302,Q96HR9,Q9NZ08,Q8TCJ2,Q9Y4W6,Q9H5K3,Q9H061,Q9Y375,Q9H490,Q96JX3,P38435,P51798,Q96S66,Q9UHX1,Q9UG56,P03915,O43681,Q96PU5,Q15043,Q9NZJ7,Q9NVI7,P37268,O15460,Q9H0B6,P00846,O75381,Q9UBM7,P04062,P51812,Q10713,O75306,P21964,O43819,P07602,Q9H6K4,Q9NX14,Q96J42,Q9Y287 76 +Dementia 0.535351228485613 3.213952711295895 0.0013092123305045 0.9975280332440892 0.0777115761076736 63 Q9Y487,P03886,P00403,O60313,O15118,Q14108,P17900,Q9UBB4,P03915,O43681,Q9NZJ7,P00846,O96008,P21912,P04062,P27544,Q9NQZ5,P07602,Q13510,Q9Y287,Q9NWW5 21 +Myoclonic seizure 0.5411729453703843 3.188327090673637 0.0014309856460454 0.9985861969922464 0.0777115761076736 57 Q9H3H5,Q5XKP0,P00846,P21912,P04062,O43292,Q8WWV3,P03915,P07602,Q9NZJ7,Q13510,Q96N66,P03886,Q01105 14 +Motor seizure 0.4476223945975865 3.186186590017892 0.001441615881526 0.9986535042948615 0.0777115761076736 107 Q9H3H5,Q9Y6N5,O43292,Q8WWV3,Q96N66,P03886,O75503,Q5XKP0,Q9NZ01,Q9UBX3,O14653,P13073,P03915,Q9NZJ7,P00846,P21912,P04062,P07602,Q9Y320,Q13510,Q01105 21 +Abnormal cellular phenotype 0.4012959181552962 3.155967199766538 0.0015996684838657 0.9993480546264808 0.0789300484119182 192 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3.0406670314721898 0.0023605471916199 0.9999801798850348 0.0859762677376427 98 Q96CU9,Q9Y2R0,O95298,Q7KZN9,O96000,Q9Y6M9,Q9BUB7,O43676,O75648,P40939,P03886,Q86Y39,Q9NPL8,P00403,Q4J6C6,Q3ZCQ8,Q9P0J0,P12235,Q70HW3,P20674,Q16836,Q9UBX3,Q9Y375,P13073,P03915,P23786,P00846,P21912,O75306,P51530,P35637,Q9NX14,O75880 33 +Abnormal retinal artery morphology 0.6846392548623688 3.030051538172864 0.0024451201067083 0.9999865597913444 0.0859762677376427 23 P00846,P21964,P03915,P07602,Q9NZJ7,Q13510,P17900,P03886 8 +Abnormal biliary tract morphology 0.6748408899430183 3.0174129315154223 0.0025494226720366 0.9999916760239158 0.0881247122459082 24 Q9NSD9,P14174,Q5XKP0,P09601,P04062,Q10713,O43681,P07602,Q14108,Q9Y276,Q9NZJ7,Q14739 12 +Poor head control 0.4950153833916809 3.01413886667122 0.0025770981760326 0.9999926697839084 0.0881247122459082 75 Q9H3H5,Q5XKP0,P21912,O96000,Q10713,P13073,Q9Y6M9,Q9P0J0,P07602,O43676,Q9NZJ7,P17900,P03886,Q86Y39,Q9H5K3 15 +Mitochondrial myopathy 0.5944248068998932 3.014127367257564 0.0025771958622766 0.9999926730726408 0.0881247122459082 33 Q96CU9,Q9NPL8,Q9Y375,P00846,P00403,Q53H12,O96000,O60313,O75306,Q9Y6M9,P12235,P03915,P51530,O43676,Q9NX14,P03886,Q86Y39 17 +Myoclonus 0.4442527876627967 2.9682405078259064 0.0029950987586555 0.9999989260158536 0.0983112503933125 98 Q96CU9,P03886,P50897,Q96AA3,O75503,Q8NBU5,Q9NPL8,P00403,Q14108,Q9UBX3,O75845,O14653,P13073,P03915,Q8NI60,Q9NZJ7,P00846,O14773,O96008,P04062,Q10713,P27544,Q9NQZ5,P07602,Q13510,Q9NWW5,Q01105 27 +Central scotoma 0.8346527595165188 2.963430361172083 0.0030423089176834 0.9999991354937016 0.0983112503933125 12 Q9H061,P03886,P00846,O60313,Q8WWV3,P03915,Q9H6K4,Q9Y287 8 +Abnormality of hepatobiliary system physiology 0.4744417112555693 2.9495136938471993 0.0031827446798897 0.9999995466462002 0.0983323461526798 83 O75648,P40939,P03886,P40855,Q8N511,Q5XKP0,P39210,P55263,Q96A33,O15118,P56589,Q9Y276,Q8TCJ2,Q16836,O75845,Q9BT22,P22830,P03915,P23786,O15460,Q9NWS8,P00846,O75381,P04062,Q10713,O75306,O43819,Q13510,P50416 29 +Abnormal retinal morphology 0.3880522921177816 2.9417385777529894 0.0032637532527157 0.9999996875978574 0.0983323461526798 227 O43505,Q96CU9,Q9H3H5,Q8NBM4,Q7KZN9,Q9Y487,Q9BV10,Q15067,O95202,O75648,Q8N2K0,P40939,P03886,Q5H8A4,Q7LGA3,P50897,P40855,O75503,Q5XKP0,P00403,O60313,P29084,Q9P0J0,Q96HR9,P51648,Q5T8D3,Q9UM00,P17900,Q16836,Q9H5K3,Q7Z4L5,Q9Y375,P38435,Q8NCH0,Q96S66,Q9UHX1,Q9UG56,P03915,Q9NZJ7,P11802,P00846,O14773,O75381,P21912,P04062,P53701,P10619,Q10713,P51812,Q13432,O75306,P21964,O43819,P07602,Q9Y4P3,Q13510,Q9NX14,Q96J42,Q9Y287,Q9NWW5 60 +Abnormality of head blood vessel 0.62954401955515 2.939282389889891 0.0032897319117493 0.9999997227649412 0.0983323461526798 28 P00846,P21964,P03915,P07602,Q9NZJ7,Q13510,P17900,P03886 8 +Abnormal muscle fiber morphology 0.4931754370949975 2.9330370656080897 0.0033566381631808 0.9999997961714656 0.0983323461526798 72 Q9H3H5,O14979,Q13586,P50402,Q9BUK6,Q99720,Q96RL7,P07196,Q9Y5L0,Q9BTV4,Q9BPX6,P61978,O43676,O75648,P03886,P13807,P00403,O60313,P12235,O75340,Q9Y276,Q70HW3,Q9H2D1,P22626,Q9Y4W6,Q9H5K3,O00483,P03915,Q8NI60,P23786,O95831,Q5JPH6,P00846,O96008,Q8NCE2,P35637,P54098 37 +Postural tremor 0.6893374518846008 2.9077698690617355 0.0036401610800604 0.9999999446533366 0.0983323461526798 20 P00846,O14773,Q9NR77,O75306,P03915,Q14108,Q9H6K4,Q9BRK0,P03886 9 +Abnormal glycosylation 0.6471821965784641 2.8846994568791087 0.0039178748808281 0.9999999845701376 0.1019983108179244 25 Q96AA3,Q9H3H5,Q8N511,Q9H0U3,Q9Y487,Q9BT22,Q10469,P46977,O75340,P51571,Q2TAA5,Q8TCJ2 12 +Abnormal social behavior 0.491310950152942 2.8758458011426655 0.004029465054699 0.999999990765387 0.1039212212478517 70 Q96CU9,O95298,O96000,Q9Y6M9,Q15067,O43676,P03886,Q86Y39,Q9NPL8,Q5XKP0,P29084,Q9P0J0,Q9Y375,Q9UHX1,O43681,Q2TAA5,Q9NZJ7,O96008,O75306,P07602,Q9NX14 21 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2.855067961736451 0.0043027620411926 0.9999999973739704 0.1047423969728415 71 O75503,Q9H3H5,Q7RTS9,P00846,Q6DKK2,O14773,P21912,P04062,Q10713,Q9NR77,P12235,Q15067,O75340,P07602,Q9NZJ7,Q13510,P40939,Q01105 18 +Increased csf lactate 0.504430803897328 2.8389648121568567 0.0045260147652832 0.9999999990601232 0.1048691723608931 58 Q96CU9,Q7KZN9,O96000,Q9Y6M9,Q9HC21,O43676,P03886,Q86Y39,Q9NPL8,P39210,P00403,Q9P0J0,Q9Y375,P13073,P03915,Q8NI60,Q9NWS8,P00846,O75306,Q9NX14 20 +Abnormal metabolic brain imaging by mrs 0.6782914084888856 2.838403079248454 0.0045339886512907 0.9999999990939938 0.1048691723608931 20 P00403,Q9Y6N5,P35610,P21912,O75306,P03915,P07602,Q9NZJ7,P03886 9 +Generalized onset motor seizure 0.5062180711286592 2.8161046269583903 0.0048609833309698 0.9999999997989236 0.1065022638624425 54 Q9H3H5,P00846,P21912,P04062,P03915,P07602,Q9Y320,Q9NZJ7,Q13510,Q96N66,P03886 11 +Decreased activity of mitochondrial complex i 0.5503751956575857 2.815713115634042 0.0048669105299048 0.999999999804337 0.1065022638624425 36 Q96CU9,Q9NPL8,Q9UBX3,Q9Y375,Q9NX14,O95298,O96000,Q9Y6M9,O43676,O75648,Q70HW3,P03886,Q86Y39 13 +Impaired proprioception 0.5413273958368255 2.811778828366013 0.0049268367972648 0.9999999998515184 0.1065022638624425 39 P41440,Q8N0X7,Q9H0B6,P00846,O14773,P07196,Q8IV08,Q9NR77,O43819,O15020,Q9H6K4,Q9BRK0,O75298 13 +Scotoma 0.7365221029592123 2.8104637350036836 0.0049470163662188 0.999999999864694 0.1065022638624425 15 Q9H061,P03886,P00846,O60313,Q8WWV3,P03915,Q9H6K4,Q9Y287 8 +Corneal opacity 0.4982140144971266 2.799318810467872 0.0051210547962627 0.9999999999392928 0.1081321339929775 60 O43505,O95202,Q06136,Q5H8A4,P40855,O75844,P56589,P51648,Q9H5K3,O75845,Q9NVI7,Q6NUK1,O75381,Q9UBM7,P04062,P10619,P53701,P08236,Q9Y4P3,Q13510,Q9NX14,Q96J42 22 +Abnormal csf metabolite level 0.4941349157863782 2.795844646052566 0.0051764276567241 0.9999999999529584 0.1083031576397709 63 Q96CU9,Q7KZN9,O96000,Q9Y6M9,Q9HC21,O43676,P03886,Q86Y39,Q9NPL8,P39210,P00403,Q9P0J0,Q9Y375,P13073,P03915,Q8NI60,Q9NWS8,P00846,O75306,Q9NX14 20 +Reduced visual acuity 0.4128256282014608 2.7684526070589 0.0056323176644315 0.9999999999942408 0.1152110693679695 124 Q96CU9,Q8NBM4,O96000,Q8WWV3,Q9Y6M9,O43676,P03886,Q86Y39,Q13144,P50897,Q96AA3,Q9NPL8,O60313,Q96HR9,P17900,Q9H5K3,Q9H061,Q9Y375,Q96S66,Q9UHX1,O43681,Q15043,Q9NZJ7,P00846,P21912,P53701,Q10713,P07602,Q9H6K4,Q9NX14 30 +Difficulty walking 0.4639919317916177 2.7497089061022004 0.0059648227507165 0.999999999998756 0.1178398543913654 79 Q9H3H5,Q99720,O43292,Q15067,Q9HC21,Q15041,O75298,Q7RTS9,Q9NR77,O75340,Q8N0X7,O14653,O43681,Q9NZJ7,Q9H0B6,P00846,O14773,P07602,P51530,Q13510 20 +Generalized myoclonic seizure 0.5206563046001547 2.7396902809308408 0.0061497105588155 0.9999999999994696 0.1209355097875224 43 Q9H3H5,P00846,P21912,P04062,P03915,P07602,Q9NZJ7,Q13510,Q96N66,P03886 10 +Abnormal tissue metabolite concentration 0.6770780951895328 2.7376364060302385 0.0061882450925283 0.999999999999556 0.1211732436494227 17 P40855,O75381,Q658P3,P07602,P56589,O43681,Q5T8D3,Q9NZJ7,P17900 9 +Muscle weakness 0.3644290572191572 2.7241070336721984 0.0064475607446996 0.9999999999998656 0.1215962117058008 300 O43505,O14979,Q13126,Q9BUK6,O96000,P07196,O43676,P03886,Q86Y39,O75298,Q5XKP0,P13473,Q4J6C6,Q3ZCQ8,P56589,P17302,P36551,Q9Y276,Q9Y4W6,Q9H5K3,Q9H936,Q8NCH0,P13073,Q9UHX1,Q9NZJ7,Q15165,P00846,P21912,Q10713,P07602,Q13510,Q9H3H5,Q99720,Q9Y6M9,Q9HC21,Q14739,P40855,Q7RTS9,P39210,P00403,Q9P0J0,Q70HW3,P17900,Q9NWM8,P03915,Q6DKK2,Q969X5,P50402,Q15067,P40939,P41440,Q9NR77,P12235,O75340,Q5T8D3,Q8N0X7,Q9BQT8,O43681,Q15043,P23786,Q6NUK1,O75381,P51530,Q92804,Q9NX14,Q96CU9,Q16637,Q9BPX6,O75648,Q9NPL8,O60313,O15269,Q8TB36,Q9Y375,P51798,Q8NI60,O15460,Q3ZAQ7,P51812,P05023,O75306,O43819,P35637,Q53H12 84 +Abnormal brain lactate level by mrs 0.7388679237614529 2.6976640431538654 0.0069827871253427 0.9999999999999888 0.1261463141289501 14 P21912,Q9Y6N5,P00403,O75306,O43819,P03915,P03886 7 +Abnormal csf protein level 0.781923933193304 2.697185346000219 0.0069928336509719 0.9999999999999892 0.1261463141289501 12 P00403,Q9NR77,P03915,P07602,Q9NZJ7,P03886 6 +Impaired social interactions 0.4948680995563485 2.687233279747728 0.0072046616058065 0.999999999999996 0.1294578803051204 52 Q96CU9,Q9NPL8,Q9Y375,Q5XKP0,O95298,O96000,Q9Y6M9,Q15067,Q9P0J0,Q9UHX1,Q2TAA5,O43676,Q9NX14,P03886,Q86Y39 15 +Hypertrophic cardiomyopathy 0.409795412733767 2.6839455919522655 0.0072758945873583 0.9999999999999972 0.1302271445284214 113 Q96CU9,P50402,Q9BTV4,Q7KZN9,O96000,Q9Y6M9,Q9BUB7,P10253,O43676,P40939,P03886,Q86Y39,Q13423,Q96IX5,Q9NPL8,Q5XKP0,P00403,P13473,O60313,P12235,Q9P0J0,Q9Y276,Q96DP5,Q16836,Q9H061,O00483,Q15056,P15586,Q9Y375,Q9P032,P49748,P03915,Q9NVI7,P00846,P21912,Q53H12,P53701,O75306,O43819,O95169,Q9Y4P3,Q9NX14,P50416 43 +Hyperintensity of cerebral white matter on mri 0.6468755658758968 2.681673310531881 0.0073254958525643 0.9999999999999976 0.1306047548499997 21 Q96AA3,O75503,P21912,O43681,O75340,P07602,Q9NZJ7,P17900 8 +Respiratory distress 0.4906735812747357 2.6615982513673173 0.0077770640099641 0.9999999999999996 0.1343791949576925 54 Q00325,Q10469,P10253,O75648,P51571,P03886,Q16134,Q8TCJ2,P49748,Q9UHX1,P03915,P23786,Q9NZJ7,O95831,P00846,P04062,P53701,O75306,O43819,O95169,P07602,Q969X5,Q13510,Q9NX14,P51970 25 +Nephropathy 0.6501508085643128 2.658984537766353 0.0078376559904953 0.9999999999999998 0.1343791949576925 20 Q7Z4L5,P00403,Q10713,Q14108,P03886 5 +Hepatic failure 0.4913820238389678 2.65267064287013 0.0079857750831746 1.0 0.1347863100298456 52 P40855,P39210,O75845,O75381,P00846,P04062,Q10713,P22830,O15118,P03915,O15460,P23786,O75648,Q13510,P40939,P03886,Q16836 17 +Brain imaging abnormality 0.5142169878880877 2.6515295711588265 0.0080128096062936 1.0 0.1347863100298456 42 Q9H3H5,P00403,Q9Y6N5,P35610,Q9BT22,P21912,Q9BV10,O75306,P03915,P07602,Q969X5,Q9NZJ7,P03886 13 +Horizontal nystagmus 0.6277670127429164 2.6514817104809185 0.0080139453206173 1.0 0.1347863100298456 23 Q9H061,P00846,O14773,P04062,Q9NZJ7 5 +Vascular skin abnormality 0.4071807928306815 2.646938361099408 0.0081224156512287 1.0 0.1352650637533971 113 Q9Y487,Q14739,P03886,Q06136,P00403,O75844,Q14108,P51648,P98194,P51798,P38435,Q9NWM8,Q8NCH0,P22830,P03915,Q6NUK1,P00846,Q9UBM7,P21912,P04062,P53701,P10619,P51812,O75306,P21964,Q9NX14,P49257 27 +Abnormal protein glycosylation 0.6388246655788014 2.6288407488252257 0.0085676472513633 1.0 0.1387325206081458 21 Q96AA3,Q9H3H5,Q8N511,Q9H0U3,Q9Y487,Q9BT22,Q10469,O75340,P51571,Q2TAA5 10 +Poor eye contact 0.508021450435192 2.6233640193985712 0.0087066192594829 1.0 0.1402151377397902 43 Q96CU9,Q9NPL8,Q9Y375,Q5XKP0,O95298,O96000,Q9Y6M9,Q9P0J0,Q9UHX1,O43676,Q9NX14,P03886,Q86Y39 13 +Progressive neurologic deterioration 0.6379054933199103 2.622787331092334 0.0087213693268966 1.0 0.1402151377397902 21 Q5XKP0,P21912,P04062,Q10713,O43681,P07602,Q9NZJ7,Q9Y287 8 +Impaired vibratory sensation 0.5771881816586023 2.6149687301697417 0.0089235624725669 1.0 0.1429642071653913 29 Q8N0X7,Q9H0B6,P00846,O14773,P07196,Q9NR77,O43819,Q9BRK0,O75298 9 +Emg neuropathic changes 0.5979061624814515 2.5919854983227384 0.0095423793856126 1.0 0.1498112362274011 26 Q16637,P39210,O14773,O60313,Q9NR77,Q969X5,O43681,P07602,Q8TB36,Q9NZJ7,Q13510 11 +Optic atrophy 0.3691116283050221 2.58934968770668 0.0096157392559033 1.0 0.1498112362274011 200 O43505,P49902,Q9H3H5,Q96CU9,Q7KZN9,O43292,Q9BPX6,Q15067,O95202,Q9HC21,Q8N2K0,P03886,O75352,Q86Y39,Q5H8A4,Q13144,P50897,P40855,Q8WWI5,P41440,Q5XKP0,P00403,P51572,O60313,Q3ZCQ8,Q9P0J0,P56589,P17302,Q96HR9,Q8TCJ2,Q9Y4W6,Q9H5K3,Q9H061,Q9H490,Q96JX3,P51798,P03915,O43681,Q96PU5,Q15043,Q9NZJ7,Q9NVI7,O15460,Q9H0B6,P00846,O75381,Q9UBM7,P51812,O75306,P21964,O43819,P07602,Q9H6K4,Q96J42 54 +Optic neuropathy 0.5897830530034912 2.588296145607935 0.009645201808617 1.0 0.1498112362274011 27 Q96CU9,Q9NPL8,Q9Y375,P00846,O96000,Q9Y6M9,Q9P0J0,P03915,O43676,Q9NX14,P03886,Q86Y39 12 +Visual loss 0.4815109645696763 2.5692976635498455 0.0101904882541556 1.0 0.1556427239351379 54 P50897,O75503,P00846,P51798,O14773,P00403,P53701,O60313,Q10713,P03915,O15460,P07602,Q9NZJ7,Q9NX14,P40939,P03886,Q9NWW5 17 +Impaired vibration sensation in the lower limbs 0.7144690374094173 2.562500101288645 0.0103921557329182 1.0 0.1557134965902098 14 Q9H0B6,P00846,Q9NR77,Q9BRK0,O75298 5 +Gait ataxia 0.4543880871255951 2.559445667175965 0.0104839242577932 1.0 0.156473423287324 75 P07196,O43292,P03886,Q5H8A4,P41440,Q8IV08,P29084,Q9NR77,P12235,O15118,Q14108,Q9UBB4,P03915,O43681,Q9NZJ7,Q9NVI7,P00846,O14773,Q10713,P07602 20 +Abnormal pyramidal sign 0.3935406876222463 2.5160911197173053 0.0118664499307361 1.0 0.16938340679948 130 P49902,Q99720,Q8NBM4,P07196,Q15067,Q9BRK0,Q8N2K0,P40939,O75298,P41440,Q8WWI5,P51572,O60313,Q9NR77,P29084,Q9P0J0,P51648,Q9NZ08,P17900,Q9Y4W6,Q9H5K3,Q8N0X7,Q9UBB4,O43681,Q8NI60,Q15043,Q9NZJ7,P00846,O14773,Q6DKK2,P21912,P51812,O75306,P07602,P35637,Q9H6K4 36 +Polyneuropathy 0.6130239308257778 2.501945688218528 0.0123512871025914 1.0 0.1746715972347968 22 P00846,P03915,P07602,Q9HC21,Q9NZJ7,Q8N2K0,P03886,Q15041 8 +Cherry red spot of the macula 0.7963547817205013 2.4950880235816486 0.0125925887768909 1.0 0.1775361285406596 9 P17900,P07602,Q13510,Q9NZJ7 4 +Hypopigmented skin patches 0.6048100027526876 2.4936653385707386 0.0126431686024353 1.0 0.1777024494980324 23 P53701,P21964,Q9NZJ7,P21912 4 +Cerebellar atrophy 0.3872802072073456 2.479685589466401 0.0131498277545587 1.0 0.1815497817332023 139 Q96CU9,O43292,O15020,O75648,Q8N2K0,Q5H8A4,P41440,O75503,Q8WWI5,Q5XKP0,Q9C0E8,P51572,Q8IV08,O60313,P46977,P29084,P12235,Q14108,Q9Y276,Q8TCJ2,Q9Y4W6,Q9H936,Q8N0X7,Q9H490,O75208,O75845,Q96JX3,P51798,Q9BT22,Q9UBB4,P13073,Q8NI60,Q15043,Q92643,Q9NVI7,O14773,Q6DKK2,Q10713,Q9Y320,Q9H6K4 40 +Schizophrenia 0.6341488142877434 2.470542794691047 0.0134908176215775 1.0 0.1815497817332023 17 P04062,P21964,P07602,Q9NZJ7,P16615 5 +Biliary tract abnormality 0.5661155823556598 2.4689069474043928 0.0135526455336314 1.0 0.1815497817332023 28 P14174,Q5XKP0,P09601,P04062,Q10713,O43681,P07602,O95202,Q14108,Q9Y276,Q9NZJ7,Q14739 12 +Periventricular white matter hyperintensities 0.7908625736278244 2.468487235878473 0.01356854910426 1.0 0.1815497817332023 9 P17900,O75503,P07602,Q9NZJ7 4 +Mania 0.6765358324293506 2.4663586850378665 0.0136494575524064 1.0 0.1815497817332023 15 P00403,P21964,P03915,P03886,P16615 5 +Lacticaciduria 0.8625476838415015 2.4627578275634296 0.0137873004995259 1.0 0.1815497817332023 7 P03915,O96000,P03886,P00846 4 +Elevated pulmonary artery pressure 0.5871819627005062 2.4627242659849125 0.0137885910177115 1.0 0.1815497817332023 25 P51798,P00403,P04062,O96000,O75844,Q6NUK1,P03915,P17302,Q14108,P20674,O14678,P03886 12 +Abnormal speech prosody 0.7887911274697961 2.4584317918352543 0.0139545281474533 1.0 0.1832081603771669 9 P04062,P03886,P00846 3 +Chorea 0.4295335040167408 2.4536040724244197 0.0141432607017026 1.0 0.1848713586448626 85 Q99720,Q9BPX6,Q96N66,P03886,Q96IX5,Q5XKP0,Q9P0J0,Q86VD7,P17900,Q9NZ01,P03915,O43681,Q9NZJ7,P00846,O75306,O43819,P07602,Q9H6K4,Q01105 19 +Erythema 0.618610773983642 2.4531302580941543 0.0141619046015597 1.0 0.1848713586448626 20 P00403,P53701,P22830,P03915,P51648,Q9NX14,P03886,Q06136,P98194 9 +Pace of progression 0.3632865237821574 2.448112949759425 0.0143606629297265 1.0 0.1858772811977606 171 Q9H3H5,O14979,Q16637,Q13126,P50402,Q99720,P07196,Q9Y6M9,O15020,Q9BRK0,Q8N2K0,O75298,O95470,P41440,Q8NBU5,Q5XKP0,P39210,P55263,Q8IV08,O60313,Q9NR77,P12235,Q9P0J0,O75340,Q8TB36,Q14108,Q9Y4W6,P15586,Q12769,O14653,P61619,Q15043,Q3ZAQ7,Q9H0B6,O14773,P04062,Q10713,P05023,P27544,Q9NQZ5,P51530,Q13510,Q9NR28 43 +Hyperreflexia 0.3596043458715207 2.4413148804233553 0.0146338888764445 1.0 0.1880355950592701 246 P49902,Q96CU9,Q9H3H5,Q99720,Q8NBM4,Q7KZN9,O43292,O15020,O14949,Q15067,Q9BRK0,Q96N66,Q8N2K0,P03886,Q14739,O75298,Q15041,Q96IX5,Q96AA3,P40855,Q8WWI5,Q7RTS9,Q5XKP0,O75503,Q8NBU5,O60313,Q9NR77,P29084,Q3ZCQ8,Q9P0J0,P56589,P17302,O75340,Q9Y276,Q96HR9,Q9NZ08,P17900,P20674,Q9Y4W6,Q9H5K3,Q9H936,Q86SQ9,Q8N0X7,Q9BQT8,O75208,Q9UBB4,Q86XL3,P13073,P03915,O43681,Q8NI60,Q15043,Q2TAA5,Q9NZJ7,Q9H0B6,P00846,O14773,Q6DKK2,P21912,P04062,O75381,Q10713,O75306,P07602,Q9Y320,P35637,Q9Y4P3,Q9H6K4 68 +Clumsiness 0.6099418665504998 2.436485930397798 0.0148307463925139 1.0 0.1882395567049827 21 O75503,O14773,Q9NR77,Q15067,P07602,Q9NZJ7,Q13510 7 +Hypocholesterolemia 0.7675936965981696 2.4349400903243796 0.0148942554785262 1.0 0.1885234215541643 10 Q15800,Q9UBM7,Q9BV10,P07602,Q8NFG4,Q9NZJ7,Q9NVI7,P37268 8 +Abnormal peripheral myelination 0.5082744205254607 2.431149355658141 0.0150510088054287 1.0 0.1899827061886351 35 Q9H0B6,P39210,P00846,Q9NR77,O15269,P03915,O43681,P07602,Q9NZJ7,P03886 10 +Mucosal telangiectasiae 0.7980841474219453 2.425837071854898 0.0152731252741242 1.0 0.1905118391571204 8 Q14739,P21912 2 +Ankle clonus 0.690113461307541 2.425289461158651 0.0152961851643542 1.0 0.1905118391571204 14 Q8N0X7,O75298,P07602,Q9NZJ7 4 +Limb ataxia 0.5748615161106014 2.4236498725573075 0.0153654116304475 1.0 0.1905118391571204 26 P41440,O14773,Q9BUK6,P04062,Q9UBB4,P07196,Q8IV08,Q10713,Q9NR77,O15020,Q14108,O75298,Q9Y4W6 13 +Increased cerebral lipofuscin 0.9110275689223074 2.422412286434561 0.0154178473084882 1.0 0.1905118391571204 6 P50897,O14773,P07602,Q9NZJ7,Q9NWW5 5 +Progressive gait ataxia 0.7286594744782944 2.4189558791599657 0.0155651280130459 1.0 0.1910347695651776 12 P00846,O14773,O43681,P07602,Q9NZJ7 5 +Diffuse white matter abnormalities 0.7795628008840506 2.413483184657181 0.0158008569664371 1.0 0.1921546370230255 9 Q9H936,O75306,O43819,Q3ZCQ8,Q9H5K3 5 +Basal ganglia calcification 0.7789869047237373 2.410669934008853 0.015923251472045 1.0 0.1921546370230255 9 P03915,P03886,O60313,P00403 4 +Muscle stiffness 0.6111025580083179 2.403363641815337 0.0162450242382097 1.0 0.1921546370230255 20 Q8NBU5,P46020,Q13586,P52732,P00846,Q15392,P49748,P07602,P23786,Q9NZJ7,Q9BRK0,P54098 12 +Ectopic calcification 0.4610839547693129 2.4027682201536957 0.0162714969805617 1.0 0.1921546370230255 59 P40855,P03886,O75431,O75845,P38435,P00403,O75381,Q9UBM7,P04062,O60313,O75844,P03915,P56589,P17302,P08236,P23786,O15228,Q14739 18 +Spastic gait 0.597424484346591 2.395108204601097 0.0166154610807134 1.0 0.1942143945709922 22 P49902,Q8N0X7,O75298,Q15043,Q9BRK0,Q15041 6 +Telangiectasia 0.5315847992277006 2.3867092697990056 0.0169999290123874 1.0 0.197699682067917 31 P03886,P00846,P21912,P03915,Q14739 5 +Diffuse cerebral atrophy 0.6620440854985318 2.3809960188709964 0.0172658985497988 1.0 0.2002844231776669 15 Q10713,Q9NZJ7 2 +Emg chronic denervation signs 0.6605583686299069 2.372194171620677 0.0176827952299269 1.0 0.2046024437967815 15 P39210,O60313,Q969X5,P07602,O43681,Q9NZJ7,Q13510 7 +Bulbar signs 0.6800882095679756 2.368134558315672 0.0178780324364005 1.0 0.2063404146689853 14 P00846,Q99720,P04062,P03915,P07602,O43681,Q9NZJ7,P03886 8 +Peripheral demyelination 0.6105666306126832 2.3623547889431005 0.0181592540219188 1.0 0.2085355938055946 19 P00846,Q9NR77,P03915,O43681,P07602,Q8TB36,Q9NZJ7,P03886 8 +Macular degeneration 0.6984614902136627 2.3605159898134804 0.0182495315646773 1.0 0.2086902848573989 13 P50897,P04062,P51648 3 +Abnormal mitochondria in muscle tissue 0.5793732184947848 2.359087937770973 0.0183199139461009 1.0 0.2088105614453601 24 Q96CU9,Q9NPL8,Q9Y375,P00403,O96000,Q9Y6M9,P03915,O43676,Q9NX14,P03886,Q86Y39 11 +Exercise intolerance 0.5063294142357618 2.349573636029916 0.0187949261265114 1.0 0.2136931799297158 34 Q9NSD9,P46020,Q9Y2R0,P00403,P13473,P12235,P03915,Q8NI60,P51530,Q9Y276,P23786,Q53H12,P40939,P03886,Q9H2D1 15 +Slowly progressive 0.4546079764286689 2.343831014862935 0.0190868169886322 1.0 0.2163542274557568 60 Q16637,Q13586,Q9H3H5,P50402,O14979,Q99720,P07196,O15020,Q9BRK0,Q8N2K0,P41440,Q8IV08,Q9NR77,P12235,Q9P0J0,O75340,Q9Y4W6,Q3ZAQ7,O14773,P05023,P51530,Q96BR5 22 +Abnormal myocardium morphology 0.3540192020016733 2.3421963243311636 0.0191706277492442 1.0 0.2163542274557568 178 Q96CU9,P50402,Q00325,Q9BTV4,Q8NBM4,Q7KZN9,O96000,Q9Y6M9,Q9BUB7,P10253,O43676,P40939,P03886,Q86Y39,Q13423,Q96IX5,P40855,P13807,Q9NPL8,Q5XKP0,P00403,P13473,O60313,P29084,P12235,Q9P0J0,P56589,Q14108,Q9Y276,Q9NZ08,Q96DP5,Q16836,P22626,Q9H5K3,Q9H061,O00483,Q15056,P15586,Q9Y375,Q9P032,Q9BT22,P49748,P03915,P23786,O00170,Q9NVI7,O96011,Q9NWS8,P00846,O75381,P21912,P04062,P53701,Q53H12,O75306,O43819,O95169,P42167,Q96DA6,P08236,Q9Y4P3,Q9NX14,P50416,P54098,O76024 65 +Abnormality of pulmonary circulation 0.5340074234399017 2.3402133763234563 0.019272725348896 1.0 0.2168378466141736 30 P51798,P00403,Q8NBM4,P04062,O96000,O75844,Q6NUK1,P03915,P17302,Q14108,Q9NZ08,O14678,P03886 13 +Progressive psychomotor deterioration 0.7799535563530128 2.339179395722358 0.0193261509766402 1.0 0.2168378466141736 8 P07602,Q10713,Q9NZJ7,P21912 4 +Fluctuations in consciousness 0.7643034304209229 2.338613381901791 0.0193554516074196 1.0 0.2168378466141736 9 P00403,P04062,O75306,O43819,P03915,O95169,P03886 7 +Hypersplenism 0.778436804339808 2.3318883508537005 0.0197065654666723 1.0 0.22020109180744 8 P04062,P07602,Q9NZJ7 3 +Lower limb spasticity 0.4196745785481237 2.331029988932027 0.0197517784227101 1.0 0.22020109180744 85 P49902,Q96CU9,Q99720,Q7KZN9,Q9BRK0,Q15041,O75298,Q5XKP0,O60313,Q9P0J0,P56589,P17302,Q8N0X7,Q9UBB4,Q9NZJ7,Q9H0B6,P00846,Q6DKK2,P21912,P04062,O75306,P07602,P35637,Q9H6K4 24 +Hepatomegaly 0.3532232145728711 2.3296658133161503 0.0198238207554906 1.0 0.2204678318001406 177 Q96CU9,P14174,Q9H3H5,O75431,O96000,Q15904,Q9Y6M9,Q15067,Q9BUB7,Q9HC21,O43676,O75648,P40939,P03886,Q86Y39,Q14739,Q96AA3,Q7Z2Z2,P40855,Q9NPL8,P39210,P09601,P35610,Q96A33,O15118,O75340,P56589,P36551,Q14108,P20674,Q86SQ9,Q9Y375,O75845,P51798,Q658P3,Q9BT22,P03915,P23786,Q9NZJ7,Q9NVI7,P31751,Q9NWS8,P00846,O75381,Q9UGP8,P04062,Q9H0U3,Q10713,O75306,P07602,P08236,Q13510,Q9NX14,P50416,Q01844,O75880 56 +Weakness due to upper motor neuron dysfunction 0.3756662282842891 2.3281299945273304 0.0199052020369774 1.0 0.2208368903957157 143 P49902,Q96CU9,Q8NBM4,Q7KZN9,Q9BRK0,P03886,Q13423,O75298,Q15041,Q7RTS9,Q5XKP0,P00403,P51572,O60313,P29084,Q9P0J0,P56589,P17302,Q9NZ08,P17900,Q8N0X7,Q9UBX3,P03915,O43681,Q9NZJ7,Q9H0B6,P00846,Q6DKK2,P21912,P04062,O75306,P07602,P35637,Q13510,Q9H6K4,P50416 36 +Cns demyelination 0.6713688483034296 2.318100240413049 0.0204438738572756 1.0 0.2258270425164729 14 P40855,Q15067,P07602,P51648,Q9NZJ7,Q5H8A4 6 +Abnormality of the coagulation cascade 0.4755409058286645 2.317254423639247 0.0204898764347372 1.0 0.2258270425164729 43 Q96AA3,Q7Z2Z2,Q9H3H5,Q5XKP0,Q96JX3,P38435,Q9Y487,Q10469,Q9BV10,Q16836,P51571,O75648,O75352,P40939,P49257,Q4KMQ2 16 +Abnormality of the biliary system 0.3835172282926797 2.3166419666913973 0.0205232432848929 1.0 0.2258270425164729 118 Q9UJW0,P14174,Q9H3H5,Q15904,O95202,O75648,P40939,Q14739,Q5H8A4,P40855,Q8WWI5,Q5XKP0,P39210,Q16134,P55263,P09601,Q96A33,O15118,P56589,P36551,Q9Y276,Q14108,Q9NSD9,P28288,Q15056,Q9Y5U9,O75845,P49748,P22830,O43681,Q9NZJ7,Q5JPH6,O96011,O75381,Q9UBM7,Q9UJS0,P04062,Q10713,P21964,P07602,Q9Y4P3,Q13510,P54098 43 +Gait disturbance 0.3380021502820352 2.3070349738239213 0.021052870469882 1.0 0.2258270425164729 324 Q9BUK6,P07196,O15020,O14949,P03886,O75298,Q5XKP0,Q9C0E8,P13473,O75844,Q4J6C6,P17302,Q9NZ08,Q9Y4W6,Q86SQ9,O14653,Q8WVQ1,Q9NZJ7,Q9H0B6,P00846,O14773,P21912,P04062,Q10713,P07602,Q13510,Q9H6K4,Q9H3H5,Q99720,Q9HC21,Q9BRK0,Q96N66,Q5H8A4,Q7LGA3,Q7RTS9,P39210,P00403,Q14108,P03915,P49902,P50402,Q8NBM4,O43292,Q15067,P40939,Q15041,P41440,O75503,Q8IV08,Q9NR77,P12235,O15118,O75340,Q5T8D3,Q8N0X7,Q9BQT8,Q96JX3,O43681,Q15043,Q9NVI7,P51530,Q96CU9,Q10469,Q9BPX6,O75648,Q13144,Q8NBU5,O60313,P29084,O15269,Q8TB36,Q9UBB4,P51812,P05023,O43819,P35637,Q9Y4P3 77 +Gowers sign 0.6476673511650602 2.295427819806969 0.0217086185578134 1.0 0.2282994601827938 15 Q9H3H5,Q9BUK6,O75340,P51530,Q5T8D3,Q13510,Q3ZAQ7,Q9H5K3 8 +Bilateral tonic clonic seizure with generalized onset 0.7708169677279187 2.2951623028944663 0.0217238246703836 1.0 0.2282994601827938 8 P04062,Q13510 2 +Inverted nipples 0.7393023026016717 2.2922300295712272 0.0218923729781752 1.0 0.2290202122968014 10 Q96AA3,Q9H3H5,Q10469,Q9BV10,Q15067,P56589,Q2TAA5 7 +Thickened skin 0.3872570218359162 2.291343635754029 0.0219435467270958 1.0 0.2290326448828092 101 P14324,Q9H3H5,O75431,P50402,Q14739,Q06136,O75352,O95470,Q7Z2Z2,Q15800,P40855,O75844,P29084,O15269,P56589,P51648,P98194,Q9NWM8,P16615,P31751,O75381,P21912,P04062,P42167 24 +Papule 0.6040229417582413 2.285614419509839 0.0222768258452648 1.0 0.2317747310865586 18 O75844,P16615,P38435,P21912 4 +Elevated hepatic transaminase 0.3825332495864272 2.284900773597698 0.0223186466741291 1.0 0.2317747310865586 103 Q9H3H5,O75431,Q15904,Q9BV10,Q15067,P10253,O75648,P40939,Q14739,Q7Z2Z2,P40855,Q8N511,Q5XKP0,P39210,P55263,P12235,Q9Y276,P20674,Q16836,Q9NSD9,P28288,Q86SQ9,Q9Y5U9,O75845,Q658P3,P49748,Q9Y6B6,P23786,Q2TAA5,Q9UJS0,Q9P2J5,Q10713,Q96DA6,Q13510,P50416,P54098,O75880 37 +Psychomotor deterioration 0.7529713676293773 2.282569933848295 0.0224557136810363 1.0 0.2317747310865586 9 P50897,P07602,Q9NZJ7 3 +Brittle hair 0.6025010257416673 2.275678313388124 0.0228652702719349 1.0 0.2328192630800133 18 Q9Y487,O75844,P29084,P17302,Q9NVI7,Q6NUK1 6 +Ventricular preexcitation 0.7508339001627097 2.271956448247951 0.0230891409414901 1.0 0.2345774806960265 9 P00846,P00403,P13473,O75306,P03915,P10253,P03886 7 +Dilated cardiomyopathy 0.4707367671705574 2.271093316281704 0.0231413295230136 1.0 0.2345875483947973 43 Q9BTV4,P40939,P03886,P00403,P13473,P12235,Q16836,P49748,P03915,P23786,P00846,P53701,O75306,O43819,O95169,P42167,Q96DA6,Q9NX14,P54098 19 +Abnormal vascular physiology 0.453126501137587 2.2589975477473057 0.0238835374171697 1.0 0.2400082706366339 51 P51798,P00403,Q14739,Q8NBM4,O96000,Q9NWM8,O75844,Q6NUK1,P04062,P03915,O15460,P17302,Q14108,Q9Y4P3,Q9NZ08,O14678,P03886 17 +Delusions 0.6007594157325052 2.256605771576345 0.0240327194106804 1.0 0.2409582501963625 17 Q9UJS0,P04062,P49770,P21964,P07602,O43681,P36551,Q9NZJ7,Q13144 9 +Abnormal choroid morphology 0.5091913465610012 2.2557231120366903 0.024087977201449 1.0 0.2409849596878593 32 O43505,P40855,Q96J42,Q5XKP0,O75381,P53701,Q10713,P56589,Q9NX14,P40939,Q9H5K3 11 +Ambiguous genitalia 0.582306610351489 2.2482144988964214 0.024562515591165 1.0 0.2446640139972137 21 O75845,P53701,Q15392,Q8TAA9,Q9NX14,Q96J42,P16435 7 +Blindness 0.412849583273803 2.24528191544031 0.024750040256235 1.0 0.2450505502694132 85 Q96CU9,Q8NBM4,O96000,Q9Y6M9,O43676,P03886,Q86Y39,Q13144,P50897,Q9NPL8,Q96HR9,P17900,Q9H5K3,Q9Y375,P51798,Q9NZJ7,P00846,P21912,P53701,O75306,P07602,Q9H6K4,Q9NX14 23 +Hallucinations 0.4589210290456333 2.240666101156805 0.0250477114792531 1.0 0.2450505502694132 46 P50897,O75503,Q8N0X7,O96008,Q6DKK2,P04062,O60313,P21964,O43681,P07602,P35637,P36551,Q9NZJ7,Q9NWW5 14 +Abnormal chorioretinal morphology 0.5137942379221007 2.239870943544635 0.0250993024966779 1.0 0.2450505502694132 31 O43505,P40855,Q96J42,Q5XKP0,O75381,P53701,Q10713,P56589,Q9NX14,P40939,Q9H5K3 11 +Loss of speech 0.5915673196921979 2.2365871548376397 0.0253133352249019 1.0 0.2456642266308492 19 P50897,O15118,P07602,Q9NZJ7,P17900 5 +Hyperesthesia 0.9649561952440546 2.2356348010517655 0.0253757030323056 1.0 0.2456642266308492 2 Q9NZJ7 1 +Bilateral tonic clonic seizure with focal onset 0.9649561952440546 2.2356348010517655 0.0253757030323056 1.0 0.2456642266308492 2 Q9NZJ7 1 +Abnormal retinal vascular morphology 0.4496987557047773 2.235058008422743 0.0254135406859499 1.0 0.2456642266308492 53 P00846,P38435,P21912,Q96S66,P21964,P03915,P07602,Q9NZJ7,Q13510,P17900,P03886 11 +Abnormal saccadic eye movements 0.5494645876495267 2.2342362045308053 0.0254675354298585 1.0 0.2456678891360252 26 Q8WWI5,P51798,O14773,P04062,Q8IV08,Q10713,O75306,O43819,O15020,P18887,Q9Y4W6 11 +Aplasia hypoplasia of the cerebral white matter 0.7428018923600223 2.2319530263234197 0.0256180676930335 1.0 0.2466008112804195 9 P03915,P03886,P00403 3 +3 methylglutaconic aciduria 0.6546013849207539 2.221028549299268 0.0263490277819911 1.0 0.2490600496739395 14 Q96JX3,Q5XKP0,Q53H12,Q9BUB7,Q3ZCQ8,Q96DA6,Q9H6K4,Q9NVI7 8 +Hypoparathyroidism 0.6732790181209977 2.2200170621914475 0.026417609428849 1.0 0.2490600496739395 13 P03915,P03886,P21964,P00403 4 +Proximal tubulopathy 0.5474997245499249 2.2194090326386706 0.0264589097050964 1.0 0.2490600496739395 26 Q96CU9,Q9NPL8,Q9Y375,P00403,O96000,Q9Y6M9,P03915,O43676,Q9NX14,P03886,Q86Y39 11 +Abnormality of prothrombin 0.6151262617791844 2.218586491334426 0.0265148694126295 1.0 0.2490600496739395 16 Q5XKP0,P38435,Q9BV10,P40939,P49257,Q16836 6 +Global brain atrophy 0.5718283195687658 2.2168356811294987 0.0266343222767231 1.0 0.2490600496739395 22 Q9H3H5,O75306,O43819,Q9UHX1,P07602,P35637,Q9NZJ7 7 +Stroke like episode 0.7394585468580729 2.2152451252742265 0.0267432440941899 1.0 0.2490600496739395 9 Q96AA3,Q9H3H5,P03886,P00403 4 +Hyporeflexia 0.3746221225262734 2.213642203554866 0.0268534016879919 1.0 0.2495786745119255 127 O43505,Q9H3H5,O14979,Q16637,Q9BUK6,Q99720,Q15067,Q9HC21,O75648,Q8N2K0,P40939,P03886,Q5H8A4,P41440,P39210,P35610,Q9NR77,O15269,P12235,P29084,Q8TB36,Q9H5K3,Q9UBB4,P03915,O43681,Q9NZJ7,Q9NWS8,Q9H0B6,P00846,P04062,Q10713,P05023,P07602,P35637 34 +Abnormal corneal epithelium morphology 0.5928759441641513 2.2125656827472815 0.0269276031571177 1.0 0.2497616956799867 18 P39210,Q8NBM4,O75844,P29084,P51648,Q14739 6 +Retinal degeneration 0.4409506321110235 2.206252114010235 0.0273663522108476 1.0 0.2514439226397421 61 P50897,O75503,Q7Z4L5,O14773,P04062,O60313,Q96S66,P29084,Q10713,Q9UG56,P51648,O75648,Q13510,Q9NWW5,Q9H5K3,Q7LGA3 16 +Proximal muscle weakness 0.4346589356142333 2.2055438539984755 0.0274159540069474 1.0 0.2514439226397421 67 Q16637,Q13586,Q9H3H5,Q13126,P50402,Q9BUK6,Q99720,Q9BTV4,P07196,Q9BPX6,P13473,O60313,P12235,O75340,Q8TB36,P36551,Q5T8D3,Q9H5K3,Q9BQT8,Q8NI60,Q3ZAQ7,P00846,P21912,P51530,P35637,Q13510 26 +Kinetic tremor 0.4828592948319281 2.2052261631503245 0.0274382281361569 1.0 0.2514439226397421 35 P41440,Q9UBB4,P29084,Q9BUB7,O15020,O75027,O43681,P07602,Q14108,Q9NZJ7,Q8N2K0,Q9Y287,Q9Y4W6,Q9NQH7 14 +Dysdiadochokinesis 0.6122389012766914 2.200466597514224 0.0277738072999396 1.0 0.2532163151014349 16 P41440,O75503,Q6DKK2,Q9BUK6,Q9UBB4,O75027,O15020,Q9Y4W6 8 +Upper motor neuron dysfunction 0.3159118005537942 2.200133479957601 0.0277974261230951 1.0 0.2532163151014349 375 O43505,P07196,O15020,P03886,O75298,P50897,Q8WWI5,Q5XKP0,Q3ZCQ8,P56589,P17302,P51648,Q9Y276,Q9NZ08,Q9NZ01,Q9Y4W6,Q9H5K3,Q9H936,Q9UBX3,Q9NZJ7,Q15165,Q9H0B6,P00846,O14773,P21912,P04062,Q10713,P07602,Q13510,Q9H6K4,Q99720,O95298,Q7KZN9,Q9BRK0,Q96N66,Q96AA3,P40855,Q7RTS9,P00403,Q9P0J0,P17900,Q9H490,P03915,Q6DKK2,Q9Y320,Q9Y287,Q01105,P49902,Q8NBM4,Q9Y487,O43292,Q15392,Q15067,P40939,Q13423,Q15041,P41440,O75503,P51572,Q9NR77,O15118,Q8N0X7,Q96JX3,Q86XL3,O43681,Q15043,Q9NVI7,O75381,Q92804,Q96CU9,Q8N2K0,Q13144,Q8NBU5,P35610,O60313,P29084,P11117,Q9UBB4,Q8NI60,Q2TAA5,P51812,O75306,O43819,P35637,Q9Y4P3,P50416 86 +Episodic vomiting 0.7044144588283665 2.192595180219927 0.0283365586967754 1.0 0.257105172175495 11 P00846,P00403,P03915,P36551,Q2TAA5,P61978,P03886 7 +Disproportionate short limb short stature 0.5845215642297331 2.189467125306923 0.028562905442701 1.0 0.2586467050167115 19 Q7RTS9,Q9UBM7,Q8WVQ1,Q15392,Q9BV10,O15228,Q32P28,Q14739,O75718,Q7LGA3 10 +Orthostatic hypotension due to autonomic dysfunction 0.7335555670757667 2.185664807395945 0.028840137424597 1.0 0.2596178972092406 9 P04062,P07602,Q9NZJ7 3 +Ventricular hypertrophy 0.4739957153784473 2.182790427085271 0.0290512469738268 1.0 0.2604947429238254 38 P00403,P21912,O75844,Q9BV10,Q6NUK1,P12235,P03915,P23786,P40939,P03886 10 +Abnormality of the gallbladder 0.4738151894380807 2.181117139845456 0.0291747534146638 1.0 0.2610912502851358 38 P40855,Q9UBM7,O75845,P04062,Q96A33,P22830,P21964,O43681,P07602,O95202,Q9NZJ7,Q5H8A4 12 +Focal t2 hyperintense brainstem lesion 0.5773700461266014 2.1760698016402644 0.0295500415770098 1.0 0.2634207986495309 20 Q96CU9,Q9NPL8,Q9Y375,O96000,Q9Y6M9,O43676,Q9NX14,P03886,Q86Y39 9 +Abnormally lax or hyperextensible skin 0.4579253729334038 2.1734648121835707 0.0297453514108572 1.0 0.2641341088460228 44 P38435,Q9NWM8,Q9Y487,O96000,Q8NCH0,P04062,Q9BV10,P51812,Q9UHX1,Q9Y4P3,Q9NX14,Q6NUK1 12 +Mortality aging 0.3747405527551735 2.171684345164873 0.0298794801351245 1.0 0.2648119496695176 106 O75431,O96000,Q15904,Q9BUB7,Q15067,Q9HC21,Q14739,Q96IX5,P40855,Q9NPL8,Q9NXE4,O75844,P56589,Q9Y276,Q8TCJ2,P20674,O75718,Q9BT22,Q9NZJ7,Q9NVI7,Q6NUK1,Q9NWS8,O75381,P04062,P51812,O43819,P07602,Q9Y4P3,Q9NX14,P16435 30 +Visual impairment 0.3401841128976355 2.166187676128723 0.0302968484827157 1.0 0.2674762230208161 287 Q96CU9,Q8NBM4,O96000,O43292,Q8WWV3,Q9Y6M9,O43676,O75648,Q96N66,P40939,P03886,Q86Y39,Q7LGA3,P50897,Q96AA3,P40855,O75503,Q5XKP0,Q13144,Q9NPL8,P00403,Q96A33,O60313,Q6P4A7,P12235,O75340,Q96HR9,P17900,Q9NZ01,Q9H5K3,Q9H061,Q9Y375,Q9H490,P51798,Q96S66,Q9UHX1,P03915,O43681,Q15043,Q9NZJ7,P37268,O15460,P00846,O14773,O75381,P21912,P53701,Q10713,Q13432,O75306,O43819,P07602,Q9Y4P3,Q9H6K4,Q9NX14,Q9Y287,Q9NWW5,Q01105 58 +Chronic pulmonary obstruction 0.8491831891119375 2.157201754016052 0.0309899478707702 1.0 0.2709846205035673 6 P09601 1 +Central apnea 0.7411632031344776 2.1506844031790324 0.031501118248405 1.0 0.2729363115831084 8 Q10713,Q9NZJ7 2 +Involuntary movements 0.3273334457283945 2.150032600588646 0.0315526361632783 1.0 0.2729363115831084 336 Q9BUK6,P07196,O15020,O14949,P03886,O75298,P50897,Q8WWI5,Q5XKP0,Q9C0E8,Q3ZCQ8,Q86VD7,Q9NZ01,Q9Y4W6,Q9H5K3,Q9H936,Q9UBX3,O14653,P13073,Q9UHX1,Q9NZJ7,P00846,O14773,P21912,P04062,Q10713,P07602,Q13510,Q9H6K4,Q9H3H5,Q99720,Q9BRK0,Q96N66,Q96AA3,P00403,Q6P4A7,Q9P0J0,Q14108,P17900,O75845,P03915,Q6DKK2,P27544,Q969X5,Q9Y287,Q9NWW5,Q01105,O43292,Q96IX5,P41440,O75503,Q9NR77,P12235,Q5T8D3,Q8N0X7,Q9BQT8,O43681,Q15043,Q9NQH7,O96008,Q9NQZ5,Q96CU9,Q16637,Q10469,Q9BPX6,Q9BUB7,O95202,Q8N2K0,Q8NBU5,Q9NPL8,O60313,P29084,P51798,Q9UBB4,Q8NI60,Q9NWS8,O75306,O43819,P35637,Q9Y4P3 80 +Areflexia 0.3885530117613389 2.1461821417454567 0.0318584497863096 1.0 0.2729363115831084 95 O43505,Q9H3H5,Q13586,Q16637,Q96RL7,P07196,Q15067,P10253,P61978,P40939,Q15041,P41440,P39210,O60313,Q9NR77,O15269,P12235,O75340,P56589,Q8TB36,Q9H5K3,Q9BQT8,O14653,Q9BT22,P18887,Q9Y6B6,O95831,O96011,Q9NWS8,P05023,Q8NCE2,Q969X5,O43819,Q13510,Q9H6K4,P54098,Q00535 37 +Memory impairment 0.4622884509176263 2.139396024383143 0.0324036086534513 1.0 0.2745545974045285 41 Q9NZ08,O96008,P00403,Q8NBM4,P03915,O43681,P07602,Q9NZJ7,Q9BRK0,P03886,Q9Y4W6,Q13144 12 +Knee flexion contracture 0.5362811418382509 2.134271770494468 0.0328205406818198 1.0 0.2745545974045285 26 P49902,Q9H3H5,P21912,Q86XL3,Q969X5,O75340,P37268,Q7LGA3 8 +Disproportionate short stature 0.5529895596266401 2.126263012829319 0.0334813659450803 1.0 0.2769162793508268 23 Q7RTS9,Q9UBM7,Q15392,Q9BV10,Q9UHX1,O15228,Q32P28,Q14739,O75718,Q7LGA3 10 +Personality changes 0.5801544834295929 2.121796514153749 0.0338548295045282 1.0 0.2790348368230464 17 P04062,P03886,P03915,P00403 4 +Choreoathetosis 0.487046770031886 2.1217431570486815 0.0338593123687502 1.0 0.2790348368230464 33 P00846,Q5XKP0,Q86VD7,Q9H6K4 4 +Atlantoaxial instability 0.9377346683354189 2.1173719557148165 0.034228292377437 1.0 0.2810645800598865 2 Q7RTS9 1 +Undetectable electroretinogram 0.9243900532600215 2.1134538055820076 0.0345619448529663 1.0 0.2825472565328593 4 P50897,O14773 2 +Generalized onset seizure 0.3706604668505164 2.1126138823905167 0.0346338295341837 1.0 0.2825472565328593 104 Q9H3H5,O43292,Q96N66,P03886,O75503,Q9C0E8,P29084,Q14108,Q9NZ01,Q9Y4W6,Q9H936,O14653,Q9UBB4,P03915,P00367,Q9NZJ7,Q9NVI7,P00846,P21912,P04062,P51812,P05023,P07602,Q9Y320,Q13510,Q01105 26 +Abnormality of lysosomal metabolism 0.837010349078555 2.10406463094249 0.035372809592985 1.0 0.2867546790433563 6 P07602,Q13510,Q9NWW5,Q9NZJ7 4 +Tetraparesis 0.4673983273037328 2.101517549539097 0.0355955590932077 1.0 0.2867546790433563 37 Q7RTS9,Q9UBX3,P00846,P21912,P07602,Q9NZJ7 6 +Spastic tetraparesis 0.5380673251169197 2.1010793951016833 0.0356339973211934 1.0 0.2867546790433563 25 Q7RTS9,P00846,P21912,P07602,Q9NZJ7 5 +Bilateral sensorineural hearing impairment 0.511839084939092 2.1003706799595716 0.0356962461392895 1.0 0.2867546790433563 29 P00403,P29084,Q15067,P03915,O43681,P07602,Q9NZJ7,P03886 8 +Paroxysmal involuntary eye movements 0.5608878789424178 2.099387842972889 0.0357827254845355 1.0 0.2867546790433563 21 Q96CU9,Q9NPL8,Q9Y375,O96000,Q9Y6M9,O43676,Q9NX14,P03886,Q86Y39 9 +Abnormal gallbladder morphology 0.5044844997934825 2.0991356524860123 0.0358049443875989 1.0 0.2867546790433563 30 P40855,O75845,P04062,Q96A33,P22830,P21964,O43681,P07602,Q9NZJ7 9 +Concentric hypertrophic cardiomyopathy 0.9186109359157164 2.0900090484260265 0.0366169868950136 1.0 0.2917896242660047 4 P03886,P00403 2 +Widened cerebral subarachnoid space 0.8788930094868856 2.0821838194110645 0.0373256826496453 1.0 0.2948728929321979 5 P03915,P03886,P00403 3 +Young adult onset 0.665656660567509 2.077208325994549 0.0377823357505329 1.0 0.2962750472923125 12 P38435,Q9H0U3,O15118,P07602,Q9NZJ7,Q14566 6 +Abnormal reflex 0.3118009519502645 2.0752583109620697 0.0379626009570384 1.0 0.2963281730581771 371 O43505,O14979,Q9BUK6,P07196,O15020,O14949,P03886,O75298,Q8WWI5,Q5XKP0,Q3ZCQ8,P56589,P17302,Q9Y276,Q9NZ08,P20674,Q9Y4W6,Q9H5K3,Q9H936,Q86SQ9,O75208,O14653,P13073,O75027,Q9NZJ7,Q9H0B6,P00846,O14773,P21912,P04062,Q10713,P07602,Q13510,Q9H6K4,Q9H3H5,Q99720,Q7KZN9,Q9HC21,Q9BRK0,Q96N66,Q14739,Q5H8A4,Q96AA3,P40855,Q7RTS9,P39210,Q9P0J0,P17900,Q9BT22,P03915,Q6DKK2,Q969X5,Q9Y320,P49902,P50402,Q8NBM4,O43292,Q15067,P40939,Q15041,Q96IX5,P41440,O75503,Q9NR77,P12235,O75340,Q8N0X7,Q9BQT8,Q86XL3,O43681,Q15043,O75381,Q96CU9,Q16637,Q8TAA9,O75648,Q8N2K0,Q8NBU5,P35610,O60313,P29084,O15269,Q8TB36,Q96HR9,Q9UBB4,Q8NI60,Q2TAA5,Q9NWS8,P51812,P05023,O75306,O43819,P35637,Q9Y4P3,P50416 95 +Macrovesicular hepatic steatosis 0.7114726395614409 2.074087261511765 0.0380712074119271 1.0 0.2966705312269562 9 Q5JPH6,Q9Y375,P39210,O75431,Q5XKP0,P23786,O75648 7 +Atlantoaxial abnormality 0.8761851704851115 2.0707935492834664 0.0383780933263748 1.0 0.2975438639956847 5 Q8NCH0,Q7RTS9 2 +Neuronal loss in central nervous system 0.6278552111076963 2.0638401610616564 0.0390328738404521 1.0 0.2980810465615864 14 P04062,O43819,O15118,P07602,Q9NZJ7 5 +Abnormal lung lobation 0.6454417807750207 2.0619301238984695 0.0392143890709382 1.0 0.2989689363112128 13 Q9UHX1,P21964 2 +Dermal atrophy 0.5137594910041854 2.0604059919693225 0.0393597445585021 1.0 0.2995786537658748 28 Q9NWM8,Q8NCH0,P53701,Q15392,O75844 5 +Infantile axial hypotonia 0.6793598322959001 2.059007026077643 0.039493565420388 1.0 0.2996876416120848 11 P17900,P07602,Q9H3H5,Q9NZJ7 4 +Abnormality of skull ossification 0.644911278729304 2.058888983924158 0.0395048746254254 1.0 0.2996876416120848 13 O75718,Q14739,O75844,Q9HC21,Q6NUK1,Q32P28 6 +Abnormal involuntary eye movements 0.3327169987512066 2.05790061590051 0.0395996746174296 1.0 0.2999102629703514 299 P49902,Q96CU9,Q9H3H5,Q99720,Q7KZN9,O96000,P07196,O43292,Q15392,Q8WWV3,O15020,Q9Y6M9,Q15067,O95202,O43676,O75648,Q8N2K0,P03886,Q86Y39,O75352,Q5H8A4,Q7LGA3,P41440,P40855,O75503,Q9NPL8,Q5XKP0,P39210,Q8IV08,O60313,Q9NR77,P29084,P12235,Q9P0J0,O75340,P56589,P17302,Q96HR9,Q5T8D3,P17900,Q9Y4W6,Q9H061,Q86SQ9,Q9Y375,Q9H490,P51798,Q9BT22,Q9UBB4,O75027,P03915,Q9NZJ7,Q9NVI7,Q6NUK1,O15460,Q9H0B6,P00846,O14773,Q6DKK2,P21912,P04062,O75381,Q9UBM7,Q10713,Q53H12,O75306,O43819,P07602,P35637,Q9Y4P3,Q13510,Q9H6K4,Q9NX14 72 +Aphasia 0.4556673971825685 2.053105775988983 0.0400623199049186 1.0 0.3021457339581123 40 O96008,P00403,P53701,P21964,P03915,Q9NX14,P03886,Q7LGA3 8 +Mitochondrial inheritance 0.8245614035087755 2.0494065452037957 0.0404223777643655 1.0 0.3021457339581123 6 P00846,P00403,P03915,O75648,P03886 5 +Phenotypic variability 0.366177654435562 2.0458937557018566 0.0407668248394266 1.0 0.302479036803259 109 Q9H3H5,O14979,P07196,P03886,O95470,P00403,O60313,Q9NR77,Q6P4A7,P36551,Q9Y276,Q70HW3,P17900,Q9Y4W6,Q9H061,Q86SQ9,Q9Y375,Q96JX3,Q9UBB4,P03915,Q8NI60,Q9NZJ7,Q3ZAQ7,Q9NWS8,P00846,P21912,P07602,Q13510,Q53H12 29 +Capillary hemangioma 0.7705818808121357 2.0428678392844057 0.0410655227440699 1.0 0.302479036803259 7 Q7LGA3,P16435,Q10469,Q9UHX1 4 +Abnormal metabolism 0.4306251851233678 2.0394364553555495 0.0414064871509114 1.0 0.302479036803259 54 P41440,Q7Z2Z2,Q9H3H5,Q96AA3,Q8N511,Q9H0U3,Q9Y487,Q9BT22,Q15904,Q10469,P46977,O75340,P51571,Q2TAA5,O14678,Q8TCJ2 16 +Abnormal brainstem mri signal intensity 0.5396025588293045 2.028774257808017 0.0424812883945056 1.0 0.305962913380522 23 Q96CU9,Q9NPL8,Q9Y375,O96000,Q9Y6M9,O43676,Q9NX14,P03886,Q86Y39 9 +Segmental peripheral demyelination remyelination 0.7674565859097753 2.028241012507738 0.0425356560068512 1.0 0.305962913380522 7 P03915,P03886,P00846,Q9NR77 4 +Mitochondrial respiratory chain defects 0.7665627581854721 2.0240534834971227 0.042964649042517 1.0 0.3081086782718019 7 P00846,O75306,P03915,O75648,P03886 5 +Abnormal epiphyseal ossification 0.5637706358581411 2.018826250726231 0.0435052816249823 1.0 0.3083892038734376 18 P40855,Q7RTS9,O75381,Q9UBM7,P38435,Q9UG56,P08236,Q14739 8 +Abnormality of glycolipid metabolism 0.7650486235519642 2.016955507800531 0.0437001566025783 1.0 0.3083892038734376 7 P17900,P07602,Q9NZJ7 3 +Abnormal auditory evoked potentials 0.7649510770647172 2.016498041087604 0.0437479228541541 1.0 0.3083892038734376 7 P07602,O60313,Q9NZJ7 3 +Microcytic anemia 0.6995812769824916 2.0134045109398477 0.0440720914395018 1.0 0.3097213542573581 9 Q9BQT8,Q9UBX3,O75027,P22830,Q13546 5 +Stuttering 0.899199244183144 2.010869891339975 0.0443392013573089 1.0 0.3106235278583579 4 P03886,P00403 2 +Posterior polar cataract 0.9130162703379224 2.0090354401984327 0.0445333753884367 1.0 0.3106235278583579 2 Q9Y287 1 +High frequency sensorineural hearing impairment 0.8985859680858066 2.008359957697912 0.0446050547407825 1.0 0.3106235278583579 4 O75844,Q13510 2 +Varicose veins 0.8613926729629873 2.00833956872242 0.0446072198452203 1.0 0.3106235278583579 5 P04062 1 +Venous insufficiency 0.8613926729629873 2.00833956872242 0.0446072198452203 1.0 0.3106235278583579 5 P04062 1 +Unexplained fevers 0.860904623681422 2.0062724186662937 0.0448271910529181 1.0 0.3114869171881836 5 Q9NZJ7 1 +Abnormal circulating protein concentration 0.3489760295741223 2.005768544273261 0.0448809481990868 1.0 0.3114869171881836 156 O43505,P14174,O14979,Q9H3H5,Q13586,P50402,Q9BUK6,Q9BTV4,Q08J23,P07196,Q9Y5L0,Q9Y6N5,Q9Y487,Q9BV10,Q9BPX6,P10253,O75648,P40939,O95470,P41440,Q7Z2Z2,P46020,Q8N511,Q5XKP0,P39210,P13473,P12235,O75340,Q6ZXV5,P36551,Q9Y276,Q86VD7,Q16836,P22626,Q9H5K3,Q9NSD9,Q15056,Q12769,O14653,Q9NWM8,Q9BT22,Q658P3,P49748,Q9Y6B6,P23786,O95831,Q3ZAQ7,Q9UJS0,P15291,Q8NCE2,Q969X5,Q96BR5,P42167,P51530,Q9Y4P3,P50416,P54098 57 +Occipital meningocele 0.860641103709202 2.005156096149392 0.0449463620078143 1.0 0.3114869171881836 5 Q10713 1 +Spasticity 0.3279231701419766 2.0012964900913235 0.0453604477778928 1.0 0.3130144152384111 309 P49902,Q96CU9,O43505,Q99720,O95298,Q7KZN9,Q9Y487,O43292,Q15392,P07196,O15020,Q9BRK0,Q96N66,Q8N2K0,P03886,O75298,Q15041,Q13144,P50897,Q96AA3,P40855,Q7RTS9,Q5XKP0,O75503,Q8NBU5,P35610,O60313,P29084,P11117,Q9P0J0,O15118,Q3ZCQ8,P56589,P17302,P51648,Q9Y276,P17900,Q9NZ01,Q9Y4W6,Q8N0X7,Q9UBX3,Q9H936,Q9H490,Q96JX3,Q9UBB4,Q86XL3,P03915,O43681,Q15043,Q2TAA5,Q9NZJ7,Q9NVI7,Q15165,Q9H0B6,P00846,Q6DKK2,O75381,P21912,P04062,P51812,Q10713,O75306,O43819,P07602,Q9Y320,P35637,Q9Y4P3,Q13510,Q9H6K4,Q92804,Q9Y287,Q01105 72 +Retinal dystrophy 0.422167089504481 1.999022174469756 0.0456059546839076 1.0 0.3142353148295708 61 O43505,Q9H3H5,Q15067,Q8N2K0,P03886,P40855,P56589,Q96HR9,Q9Y276,Q5T8D3,Q9H5K3,Q86SQ9,P38435,P03915,P00846,O75381,P53701,Q10713,Q9NX14,Q9Y287 20 +Abnormal nervous system electrophysiology 0.3360925092344633 1.996382799438562 0.045892271612665 1.0 0.3147926371024888 187 Q9H3H5,Q99720,P07196,O43292,Q10469,Q15067,O95202,Q96N66,Q8N2K0,P03886,Q5H8A4,P50897,P40855,Q8WWI5,O75503,P39210,Q8NBU5,P00403,Q96A33,O60313,Q9NR77,O15269,Q3ZCQ8,O75340,P56589,Q8TB36,Q14108,Q9Y276,Q9NZ01,Q9Y4W6,Q9H936,Q9UBX3,Q9UBB4,P13073,P03915,O43681,P00367,Q2TAA5,Q9NZJ7,O75381,O14773,P21964,Q9NQZ5,P07602,Q9NWW5 45 +Increased serum lactate 0.3624716801288268 1.99637659303827 0.0458929466574558 1.0 0.3147926371024888 116 Q96CU9,O95298,Q7KZN9,Q9Y6M9,Q9BUB7,O14949,O75648,P03886,Q86Y39,Q5XKP0,P00403,P35610,Q6P4A7,Q3ZCQ8,Q9P0J0,P12235,Q9Y276,Q86VD7,Q70HW3,P20674,Q9UBX3,Q9Y375,Q96JX3,P13073,P03915,Q8NI60,Q9NVI7,Q9NWS8,P00846,P21912,O75306,O43819,Q53H12,O75880 34 +Fingerprint intracellular accumulation of autofluorescent lipopigment storage material 0.9098873591989984 1.9952606485124464 0.0460144594143521 1.0 0.3151543393670574 2 Q9NWW5 1 +Migraine 0.5116885141145693 1.9924641450874403 0.0463201554092027 1.0 0.3163024621236468 27 O96011,Q13586,P00403,Q9Y6N5,Q8NBM4,O00170,O60313,P12235,P03915,Q9NQZ5,Q9NZ08,P03886 12 +Abnormality of corneal stroma 0.6329660530182697 1.9901307621226645 0.0465765329060667 1.0 0.3171079848077236 13 P04062,O75845,Q13510 3 +Redundant skin 0.5111843514506076 1.9884851223811972 0.0467580628144645 1.0 0.317871578361835 27 P38435,Q8NCH0,Q9Y487,O96000,P51812,Q9BV10,Q9NX14,Q6NUK1 8 +Sensory neuropathy 0.45080896770808 1.985348809498386 0.0471056770994393 1.0 0.3197603147698238 39 Q9H0B6,P00846,P00403,Q8IV08,O60313,Q15067,P03915,P40939,P03886,Q15041 10 +Hypointensity of cerebral white matter on mri 0.7580209788393599 1.98393984839838 0.047262545970081 1.0 0.3203505704658453 7 Q9NZJ7 1 +Muscle spasm 0.4197473940297936 1.9812071619278415 0.0475680463942267 1.0 0.3214701896435795 62 Q16637,Q9H3H5,P00846,P04062,P07196,Q9NR77,P05023,P12235,O75340,P51530,P35637,P23786,Q92804,Q9H6K4,P40939,Q15165,Q5H8A4,O75298 18 +Retinal telangiectasia 0.8087429233778447 1.9794978781825543 0.0477599782997792 1.0 0.3222919301466697 6 P03915,P03886,P00846 3 +Ventricular arrhythmia 0.4450338183876764 1.972657955806851 0.0485345451769327 1.0 0.3260781319658446 41 P42892,P00846,P50402,Q9NX14,P00403,Q9BTV4,P13473,P21912,O75306,P12235,P03915,P36551,P10253,P23786,Q96DP5,P03886 16 +Raynaud phenomenon 0.8062171559565277 1.9682885639343295 0.0490348450303022 1.0 0.3284761110070829 6 O75844 1 +Spastic paraparesis 0.5416514730272075 1.9635387746950228 0.0495836036038859 1.0 0.3299192051716502 21 Q5XKP0,Q6DKK2,P21912,P04062,Q9H6K4 5 +Bilateral tonic clonic seizure 0.381848310813483 1.9626892780141283 0.0496822897355824 1.0 0.3299192051716502 91 P00846,Q14739,P04062,P00403,P27544,P03915,P07602,Q9Y320,Q9HC21,Q9NZJ7,Q13510,P03886,Q5H8A4,Q01105 14 +Urinary urgency 0.7027286142010596 1.959741216208125 0.0500260451066707 1.0 0.3315183285404391 8 P04062,O75298 2 +Increased c peptide level 0.901752190237797 1.9593842378504256 0.0500678051833225 1.0 0.3315183285404391 2 P40939 1 +Tremor 0.3334667765312555 1.9565408983625427 0.0504014694871535 1.0 0.3325328867859908 182 Q9H3H5,Q16637,Q9BUK6,Q99720,P07196,O43292,Q9BPX6,Q9BUB7,O15020,Q9BRK0,Q8N2K0,P03886,P41440,O75503,Q9C0E8,O60313,Q9NR77,P29084,Q6P4A7,P12235,Q14108,Q5T8D3,Q9Y4W6,Q9H936,Q86SQ9,P51798,O14653,Q9UBB4,P03915,O43681,Q8NI60,Q15043,Q9NZJ7,Q9NQH7,P00846,O14773,Q6DKK2,P21912,P04062,Q10713,O75306,Q9NQZ5,P07602,P35637,Q9Y4P3,Q13510,Q9H6K4,Q9Y287 48 +Myopathy 0.3600398300190402 1.9562415384901832 0.0504367073725782 1.0 0.3325328867859908 104 Q9H3H5,O14979,Q13586,Q13126,P50402,Q9BUK6,Q9BTV4,Q00325,P07196,Q9Y5L0,Q96RL7,O43676,O75648,P40939,P03886,Q86Y39,P00403,P13473,O60313,P12235,O75340,P22626,Q15056,Q9Y375,Q9P032,Q9NWM8,Q8NCH0,P03915,Q9Y6B6,P23786,Q3ZAQ7,Q9NWS8,P00846,P21912,P15291,O75306,Q8NCE2,Q969X5,P42167,P51530,Q9Y4P3,Q53H12,P54098,O76024 44 +Abnormality of retinal pigmentation 0.3954757096059011 1.9556082136645965 0.0505113245750872 1.0 0.3325328867859908 81 Q96CU9,Q9BUK6,Q7KZN9,Q15067,P40939,P03886,P40855,P00403,Q9P0J0,P56589,Q96HR9,P51648,Q16836,Q7Z4L5,Q96S66,Q9UG56,P03915,P00846,O75381,P21912,P53701,P51812,Q13432,O75306,Q9NX14 25 +Hypothermia 0.6432852134746869 1.9524904921869408 0.0508799986803893 1.0 0.3340002205638169 12 P00846,P03886,Q5XKP0 3 +Knee clonus 0.8998748435544559 1.951092568467728 0.0510460350974646 1.0 0.3345935732140148 2 O75298 1 +Peripheral axonal neuropathy 0.4143522232377477 1.950501001386579 0.051116434144437 1.0 0.3345935732140148 65 Q9H0B6,P39210,P00846,P00403,Q8IV08,O60313,Q9BPX6,P12235,Q15067,P03915,P07602,Q9HC21,Q9NZJ7,Q9NVI7,P03886 15 +Respiratory failure 0.4167386176222115 1.9473598178576272 0.0514916118724189 1.0 0.3365685671889064 62 Q8NBU5,Q16637,Q5XKP0,Q9NX14,Q9BT22,P53701,O75306,Q9BUB7,O43819,P07602,P23786,Q70HW3,Q9NZJ7,Q92804,P40939,Q13510,Q15165 17 +Centrocecal scotoma 0.846539304729079 1.9452409802800448 0.0517459817584695 1.0 0.3370091085086628 5 P03915,P03886,O60313,P00846 4 +Depression 0.3593923179705438 1.944761525173872 0.0518036867686366 1.0 0.3370091085086628 107 Q9BUK6,Q96N66,P03886,P50897,P00403,P12235,P36551,Q9Y276,Q9NZ01,Q9UBB4,P03915,O43681,Q9NZJ7,O15460,Q15165,Q6DKK2,P04062,P51812,P21964,P07602,P51530,P35637,Q9Y4P3,Q92804,Q9NWW5 25 +Decerebrate rigidity 0.8830639929622477 1.944639824105603 0.0518183427138527 1.0 0.3370091085086628 4 P07602,Q9NZJ7 2 +Punctate cataract 0.8820068482782146 1.940286647605782 0.0523448631853875 1.0 0.3370091085086628 4 Q8WWV3,Q9H6K4 2 +Underdeveloped supraorbital ridges 0.6239945609918391 1.938136206118252 0.0526066072420436 1.0 0.3380693890365276 13 P40855,O96011,P52732,O75381,Q08J23,P56589,Q6NUK1,P16435 8 +Abnormal pericardium morphology 0.6708740793693128 1.9367270573297712 0.05277871646911 1.0 0.3387003905622719 10 P14174,Q8NBM4,P04062,Q14108,Q9NZ08,O15460 6 +Peripheral axonal degeneration 0.3951226707178374 1.935666600126922 0.0529085476650514 1.0 0.3390586928689033 80 Q9BPX6,Q15067,Q9HC21,P03886,P41440,P39210,P00403,Q8IV08,O60313,O15269,P12235,Q9BQT8,P03915,Q9NZJ7,Q9NVI7,Q9H0B6,P00846,Q6DKK2,P07602 19 +Posterior embryotoxon 0.5424964806985142 1.9346176529424597 0.0530372321437777 1.0 0.3390804031368086 20 P40855,Q15056,O75381,P53701,P21964,P56589,Q9Y4P3,Q9NX14,Q7LGA3 9 +Photophobia 0.4360584979356949 1.93096053482484 0.053487933098419 1.0 0.3399191531996616 43 Q86SQ9,Q8NBM4,Q96S66,P29084,Q13432,Q8WWV3,P07602,Q96HR9,P51648,Q9NZJ7,Q9NZ08,P40939,Q9Y287,Q9Y4W6 14 +Retinal vascular tortuosity 0.5876974116900961 1.9288539847925712 0.0537489917153102 1.0 0.3406333057255207 15 P00846,O75306,P21964,P03915,P03886 5 +Abnormality of extrapyramidal motor function 0.3943014449928113 1.925308626675637 0.0541907590464196 1.0 0.3425520764012412 80 Q99720,Q9BPX6,O14949,Q96IX5,P35610,P12235,P17900,Q96JX3,Q9UBB4,Q15043,Q9NZJ7,P11802,Q9H0B6,Q6DKK2,O96008,P04062,P07602,P35637,Q9H6K4,Q9NWW5 20 +Contractures of the joints of the lower limbs 0.4207777034621845 1.9236124065965323 0.054403184772507 1.0 0.342967920513083 52 P49902,Q9H3H5,P50402,Q99720,P21912,Q86XL3,Q969X5,O75340,Q9HC21,P23786,Q8N2K0,P37268,Q7LGA3 13 +Abnormal lung development 0.4248942605457587 1.9233573084482125 0.0544351919451442 1.0 0.342967920513083 47 Q7Z4L5,Q9H3H5,O96000,O75844,Q6NUK1,Q9UHX1,P21964,Q8TAA9,Q14739,Q5H8A4 10 +External ophthalmoplegia 0.5305350439814008 1.921316576185524 0.0546918086189684 1.0 0.342967920513083 22 P21912,P00403,P12235,P03915,P51530,P03886 6 +Temperature instability 0.6950548789071013 1.9211231566887104 0.054716182866666 1.0 0.342967920513083 8 P07602,Q9HC21,Q9NZJ7 3 +Toe walking 0.5400585842622483 1.9174914366592355 0.0551755278498236 1.0 0.3430566860576609 20 P50402,Q9BTV4,Q99720,O43681,P07602,P35637,Q9NZJ7,O95831,P40939 9 +Limited extraocular movements 0.7438923237102 1.917210634634133 0.0552111775609303 1.0 0.3430566860576609 7 Q3ZAQ7,O75306,O43819 3 +Abnormality of the achilles tendon 0.653160399623907 1.9170905226254904 0.0552264324522084 1.0 0.3430566860576609 11 P50402,Q9BTV4,O60313,Q8N2K0,Q15041 5 +Decreased number of peripheral myelinated nerve fibers 0.5486315907322311 1.9163280469029855 0.055323353057346 1.0 0.3430566860576609 18 Q9H0B6,P39210,Q96RL7,P07196,Q9NR77,O15269,Q8TB36,P54098 8 +Episodic respiratory distress 0.8755510033668799 1.9136657404732091 0.0556628792139717 1.0 0.3433547392675283 4 P03886,P00846 2 +Juvenile onset 0.4389925447728127 1.9135876332777584 0.0556728664440375 1.0 0.3433547392675283 41 P41440,P39210,P50402,P51798,O14773,Q9H0U3,P07196,Q9NR77,P49770,O75027,O15118,Q13510,Q14566,Q13144 14 +Fasciculations 0.445052220234863 1.910626424151387 0.0560526061090018 1.0 0.3442492222790501 38 Q8NBU5,Q16637,Q9NWS8,Q9BQT8,O43819,Q969X5,P07602,P35637,Q9NZJ7,Q13510 10 +Multiple lipomas 0.7423887493004006 1.910081731648308 0.0561226907556635 1.0 0.3442492222790501 7 P03915,Q8TAA9,Q9BUK6 3 +Abnormal visual electrophysiology 0.4198257796130416 1.909243449043476 0.0562306936905112 1.0 0.344450586216474 51 P50897,O75503,Q9H936,Q86SQ9,P00846,P51798,O14773,O60313,Q96S66,P12235,Q15067,O43681,P07602,Q96HR9,Q9NZJ7,Q53H12,P40939 17 +Abnormal renal tubule morphology 0.5068830293302176 1.9072799767337183 0.056484341685832 1.0 0.3452061547075074 26 P00846,O75306,O43819,P03915,O95169,P23786,Q9Y276,Q9Y4P3,P03886,Q9NQH7 10 +Parkinsonism with favorable response to dopaminergic medication 0.6513223541649731 1.907049415153451 0.0565141887968172 1.0 0.3452061547075074 11 P04062,Q9NZJ7 2 +Fetal distress 0.4946468703476067 1.9065409562264797 0.0565800572207197 1.0 0.3452061547075074 28 Q96CU9,Q9NPL8,Q9Y375,Q9NX14,O96000,Q9Y6M9,O43676,Q9NVI7,P03886,Q86Y39 10 +Paraparesis 0.4813278456684398 1.9054784166707623 0.0567179104327086 1.0 0.345587055322701 30 Q8N0X7,Q5XKP0,Q6DKK2,P21912,P04062,P17302,P35637,Q13510,Q9H6K4 9 +Abnormal cns myelination 0.3492905244119828 1.898939724652632 0.0575724015137106 1.0 0.3481297199914367 143 Q96CU9,Q9H3H5,Q99720,Q7KZN9,O96000,Q9Y6M9,Q15067,O43676,P03886,Q86Y39,Q5H8A4,Q7LGA3,Q13144,P40855,Q9NPL8,P51572,P29084,Q9P0J0,O75340,Q8TB36,P51648,Q5T8D3,Q9Y375,Q9H490,O43681,Q9NZJ7,Q9NWS8,P21912,O75306,O43819,P07602,Q9NX14 32 +Progressive external ophthalmoplegia 0.5828654300747996 1.898638090522915 0.0576120766138883 1.0 0.3481297199914367 15 P00403,P12235,P03915,P51530,P03886 5 +Abnormality of lipoprotein cholesterol concentration 0.5827987441434554 1.898220377877201 0.0576670575018551 1.0 0.3481297199914367 15 P37268,Q15800,Q8N511 3 +Dyspnea 0.359858389294218 1.8976146916107317 0.0577468576485471 1.0 0.3481527654547934 101 Q10469,P51571,O75648,P03886,O75844,P12235,Q8TCJ2,Q9UHX1,P03915,P23786,Q9NZJ7,Q15165,P00846,P04062,P53701,O75306,O43819,Q969X5,P07602,P51530,Q13510,Q92804,Q9NX14 23 +Abnormal thoracic spine morphology 0.4869401746179836 1.8962594155215184 0.057925749997433 1.0 0.3486221547989627 29 Q7RTS9,O75845,P04062,Q10469,P29084,O75844,Q9UHX1,P51648 8 +Ovotestis 0.8826658322903745 1.874875512322257 0.0608098516168482 1.0 0.3618581040368814 2 P53701 1 +Joint hemorrhage 0.8820400500625849 1.872097064777806 0.0611931760181472 1.0 0.3623306669356017 2 P38435 1 +Urticaria 0.6449351384640206 1.8720707627532376 0.0611968142778851 1.0 0.3623306669356017 11 P51648 1 +Cardiac conduction abnormality 0.4585670076249409 1.8693873483520231 0.0615689434722255 1.0 0.363074516074308 33 Q9H490,P50402,P00846,P00403,P21912,O75306,O43819,P03915,O95169,P17302,P23786,Q8NC56,P03886 13 +Arthritis 0.4247654203292045 1.867107342993746 0.0618865992023067 1.0 0.3642329329809831 45 P14174,Q93063,P51798,Q8NBM4,P61619,P04062,Q8WVQ1,O00170,O75844,P21964,O15460,Q14108,Q13510,Q9NZ08,Q14739 15 +Abnormal left ventricle morphology 0.4641715251254877 1.866836897477739 0.0619243681344796 1.0 0.3642329329809831 32 P13807,O75431,O75208,P00403,P21912,Q6NUK1,P12235,P03915,O60566,P10253,O00170,P40939,P03886,P54098,O75880 15 +Supranuclear gaze palsy 0.5314861592899939 1.85701520329654 0.0633089911127005 1.0 0.3689456332933147 20 P04062,P07602,Q9NZJ7,Q99720 4 +Retinopathy 0.482077355514347 1.8558743163993627 0.0634714746074354 1.0 0.3689456332933147 29 P11802,Q9Y375,P52732,P00846,Q8NBM4,Q5JRA6,O75306,O43819,O95169,O95202,P51648,Q9NZ08,P40939,Q5H8A4 14 +Distal peripheral sensory neuropathy 0.7810183484395319 1.8557623205049685 0.0634874434589827 1.0 0.3689456332933147 6 P03915,P03886,P00403 3 +Biliary tract neoplasm 0.8606468012265925 1.851971308422903 0.0640299430471338 1.0 0.3689456332933147 4 P07602,Q9NZJ7 2 +Neoplasm of the gallbladder 0.8606468012265925 1.851971308422903 0.0640299430471338 1.0 0.3689456332933147 4 P07602,Q9NZJ7 2 +Abnormality of central nervous system electrophysiology 0.3427775296154126 1.851782228063317 0.0640571006482946 1.0 0.3689456332933147 151 Q9H3H5,P07196,O43292,Q10469,Q15067,O95202,Q96N66,P03886,Q5H8A4,P50897,P40855,Q8WWI5,O75503,Q8NBU5,P00403,Q96A33,O60313,Q3ZCQ8,O75340,P56589,Q14108,Q9Y276,Q9NZ01,Q9Y4W6,Q9H936,Q9UBX3,Q9UBB4,P13073,P03915,P00367,Q2TAA5,Q9NZJ7,O75381,P21964,Q9NQZ5,P07602 36 +Sclerocornea 0.6253019416963985 1.8509624131651397 0.0641749606579598 1.0 0.3689456332933147 12 P53701,O95202,Q9NX14,Q96J42,Q6NUK1,Q5H8A4 6 +Abnormality of femur morphology 0.401685241339979 1.8496527185968228 0.0643636192540004 1.0 0.3692677331868175 69 O75431,Q9Y487,Q10469,Q9BV10,Q14739,Q7LGA3,Q7Z2Z2,Q7RTS9,Q96A33,O75844,P29084,P17302,O75718,P51798,Q8WVQ1,Q9UHX1,Q9NZJ7,Q32P28,P04062,P51812,P07602,Q8NC56,P16435 23 +Abnormal factor ix activity 0.8764080100125242 1.8470700768023391 0.0647369846283392 1.0 0.3703181817316482 2 P38435 1 +Erlenmeyer flask deformity of the femurs 0.8591108328115082 1.845594918228557 0.0649510449368369 1.0 0.3706172950194105 4 P04062,P07602,Q9NZJ7 3 +Very long chain fatty acid accumulation 0.7285848593974251 1.8443884813280056 0.065126544787351 1.0 0.3711565027557741 7 P40855,O96011,O75381,P56589,Q5T8D3 5 +Generalized hyperkeratosis 0.8585960702300608 1.8434571847798984 0.0652622874327693 1.0 0.371468075797452 4 O75844 1 +Hyperreflexia in upper limbs 0.6791095489964458 1.8403592977494352 0.065715504947168 1.0 0.3735836770073498 8 O75298 1 +Hypertonia 0.3011558259271876 1.8310192854623613 0.0670976645991028 1.0 0.3787886017073717 376 O43505,P07196,O15020,P03886,O75352,O75298,P50897,Q5XKP0,Q9NXE4,Q9C0E8,Q3ZCQ8,P56589,P17302,P51648,Q9Y276,Q9NZ01,Q9Y4W6,Q9H936,Q9UBX3,Q86SQ9,Q9NZJ7,Q15165,Q9H0B6,P00846,P21912,P04062,Q10713,P07602,Q13510,Q9H6K4,Q9H3H5,Q99720,O95298,Q7KZN9,Q9HC21,Q9BRK0,Q96N66,Q14739,Q7LGA3,Q96AA3,P40855,Q7RTS9,Q9P0J0,P17900,Q9H490,P03915,Q6DKK2,Q9Y320,Q9Y287,Q01105,P49902,Q9Y487,O43292,Q15392,Q15067,Q15041,O75503,P12235,O15118,Q8N0X7,Q96JX3,Q86XL3,O43681,Q15043,Q9NVI7,O75381,O96008,Q92804,Q96CU9,Q10469,Q9BPX6,Q8N2K0,Q13144,Q8NBU5,P35610,O60313,P29084,P11117,Q9UBB4,Q2TAA5,Q9UBM7,P51812,O75306,O43819,P35637,Q9Y4P3 86 +Abnormal abdomen morphology 0.3291931711292351 1.829810202556713 0.0672783246593093 1.0 0.3787886017073717 223 Q96CU9,P14174,Q9H3H5,O75431,Q8NBM4,O96000,Q15904,Q15392,Q9Y6M9,Q15067,Q9BUB7,Q9HC21,O43676,O75648,P40939,P03886,Q86Y39,Q14739,Q96AA3,Q7Z2Z2,P40855,Q9NPL8,P39210,P09601,P35610,Q96A33,O15118,O75340,P56589,P36551,Q14108,Q9NZ08,P20674,Q9NSD9,Q86SQ9,Q9Y375,O75845,P51798,Q658P3,Q9BT22,P03915,P23786,Q9NZJ7,Q9NVI7,P23458,P31751,Q9NWS8,P00846,O75381,Q9UGP8,P04062,P10619,Q9H0U3,Q10713,O75306,P21964,P07602,P08236,Q13510,Q9NX14,P50416,Q01844,O75880 63 +Leukodystrophy 0.4069425733149049 1.8278392050937295 0.0675736873757109 1.0 0.3792233296025154 61 Q96CU9,Q9NPL8,Q9Y375,P21912,Q7KZN9,O96000,O75306,Q9Y6M9,Q15067,Q9P0J0,O43681,P07602,O43676,Q9NZJ7,Q9NX14,P03886,Q86Y39 17 +Achilles tendon contracture 0.6628396558173115 1.8232826342285635 0.0682605950860577 1.0 0.3792233296025154 9 Q8N2K0,O60313,P50402,Q9BTV4 4 +Cutis laxa 0.453316284968483 1.822126696126852 0.0684357638949091 1.0 0.3792233296025154 33 P38435,Q8NCH0,Q9Y487,O96000,P51812,Q9BV10,Q9Y4P3,Q9NX14,Q6NUK1 9 +Left ventricular hypertrophy 0.4836065742099962 1.8165056141158216 0.0692928475307652 1.0 0.3819102791013522 28 P13807,O75431,O75208,P00403,P21912,Q6NUK1,P12235,P03915,P10253,O00170,P40939,P03886,P54098,O75880 14 +Male pseudohermaphroditism 0.7718999130007691 1.8147385075932263 0.0695641043290005 1.0 0.3821855228243169 6 Q96J42,P53701 2 +Aortic valve stenosis 0.6735076491060406 1.8118209434467056 0.0700138679365058 1.0 0.3839141702332473 8 O75844 1 +Cerebral dysmyelination 0.6734665029302614 1.8116110149295408 0.0700463217623297 1.0 0.3839141702332473 8 P07602,Q9NZJ7 2 +Abnormality of fontanelles 0.4217123424442405 1.810564612066125 0.0702082742383705 1.0 0.3843420699644129 44 P40855,O75381,Q08J23,Q9Y487,Q9BT22,Q8NCH0,O75844,Q6NUK1,P51812,P56589,P17302,O15228,Q32P28,P20674,P16435,O75718 16 +Pendular nystagmus 0.7210347622859189 1.8082726335123969 0.0705640789400816 1.0 0.3853690222925556 7 P00846 1 +Urinary bladder sphincter dysfunction 0.6465717655887895 1.8069627637661805 0.070768085248732 1.0 0.385495887461506 10 O75298,Q9BRK0 2 +Abnormal ldl cholesterol concentration 0.5838426011667126 1.798890444777862 0.0720360123810324 1.0 0.3884697930911278 14 P37268,Q15800,Q8N511 3 +Coronal craniosynostosis 0.7188493356321208 1.79779462090691 0.0722095600966121 1.0 0.3884697930911278 7 Q6NUK1,P16435,Q9NX62 3 +Impaired visuospatial constructive cognition 0.6575212113000651 1.7954384684234264 0.0725838680720956 1.0 0.3892779430226689 9 P03886,Q10713,P00403 3 +Hypertrophic nerve changes 0.8642052565707123 1.7927202439081666 0.0730176678804988 1.0 0.3904003520582544 2 Q9NR77 1 +Abnormality of krebs cycle metabolism 0.766986861067286 1.7925691439511315 0.0730418439368174 1.0 0.3904003520582544 6 P03886,P00846 2 +Corneal erosion 0.8108190106132998 1.7919614087372484 0.0731391479812186 1.0 0.3904003520582544 5 P51648 1 +Hypoglycemic seizures 0.7654862628368094 1.785788888231825 0.0741334465522314 1.0 0.3926930082107795 6 P00367,P40939,Q13423,Q16836 4 +Airway obstruction 0.5814598211728618 1.7843261115283762 0.074370689678251 1.0 0.3933704929659722 14 P09601,O75844,P21964 3 +Hyperventilation 0.808841413091074 1.7834142369083044 0.0745188974016726 1.0 0.3933704929659722 5 P03886,P00846 2 +Abnormality of the vasculature of the eye 0.3879516055204214 1.7828267513182032 0.0746145096611134 1.0 0.3934219600313257 76 P03886,P00846,P38435,P21912,P10619,Q96S66,P21964,P03915,P07602,Q9NZJ7,Q13510,P17900,Q14739 13 +Visual field defect 0.4078333024191296 1.772166658741154 0.0763668963960635 1.0 0.4005497749635246 48 Q9H061,P40855,O75381,P00846,P00403,Q9Y287,O60313,O75306,Q8WWV3,P03915,O15460,P56589,Q8TC12,Q9H6K4,P03886 15 +Weakness of muscles of respiration 0.4341458562025421 1.7717246358194103 0.0764402781056372 1.0 0.4005497749635246 36 Q7RTS9,P50402,Q9BTV4,Q9Y5L0,P12235,Q15067,Q8NCE2,Q969X5,P36551,P10253,Q13510,O95831,P54098,P22626,Q9H5K3 15 +Arteriosclerosis 0.5451045998700892 1.7681587453113157 0.0770343688505068 1.0 0.4018739817691392 16 Q13510,O75844,O75845,P38435 4 +Polar cataract 0.8404350901329056 1.767798771328847 0.0770945504092259 1.0 0.4018739817691392 4 Q9Y287,Q7LGA3 2 +Orthostatic hypotension 0.5618653288060691 1.7661556158809042 0.0773697449890784 1.0 0.4028501949317698 15 P04062,P07602,Q9NZJ7 3 +Abnormal cornea morphology 0.3308611434517157 1.7632127833557232 0.0778646085492147 1.0 0.4045075242318615 163 O43505,Q9H3H5,Q8NBM4,O95202,O75648,Q14739,Q06136,Q5H8A4,Q7LGA3,P40855,P39210,O75844,P29084,P12235,P56589,P17302,Q96HR9,P51648,Q9NZ08,Q9H5K3,O75845,Q9NWM8,Q8NCH0,Q2TAA5,Q9NVI7,Q6NUK1,O75381,Q9UBM7,P04062,P53701,P10619,Q53H12,P21964,P08236,Q9Y4P3,Q13510,Q9NX14,Q96J42 38 +Abnormal full field electroretinogram 0.6635336150646148 1.760800784014012 0.0782721271140771 1.0 0.405704622665952 8 P50897,P00846 2 +Abnormal light and dark adapted electroretinogram 0.6635336150646148 1.760800784014012 0.0782721271140771 1.0 0.405704622665952 8 P50897,P00846 2 +Pigmentary retinopathy 0.405886073555263 1.7590808356316805 0.0785637795011615 1.0 0.4062273288603352 51 P00846,P00403,P21912,Q7KZN9,P53701,Q96S66,Q15067,Q9P0J0,P03915,Q9UG56,Q9NX14,P40939,P03886,Q16836 14 +Saccadic smooth pursuit 0.8382436027254587 1.7586384146405811 0.0786389438452896 1.0 0.4062273288603352 4 O14773 1 +Focal segmental glomerulosclerosis 0.4981223669295452 1.7562957503786036 0.0790379225269686 1.0 0.4066294782304713 24 Q12769,P00403,P61619,P03915,Q14108,P03886,O95470 7 +Scaphocephaly 0.837626441236131 1.7560575355699517 0.0790785849043222 1.0 0.4066294782304713 4 P40855 1 +Variable expressivity 0.3760515610817392 1.7533355461297453 0.0795444274152914 1.0 0.4066294782304713 84 Q9H3H5,P07196,P03886,O95470,P00403,Q9NR77,Q6P4A7,Q9Y276,Q70HW3,P17900,Q9Y4W6,Q9H061,Q86SQ9,Q9Y375,Q96JX3,P03915,Q8NI60,Q9NZJ7,Q9NWS8,P07602,Q13510,Q53H12 22 +Multiple glomerular cysts 0.9355242566510124 1.7514380822110869 0.0798704780461423 1.0 0.4066294782304713 3 P03886,P00846 2 +Vascular tortuosity 0.9355242566510124 1.7514380822110869 0.0798704780461423 1.0 0.4066294782304713 3 P03886,P00846 2 +Low plasma citrulline 0.9355242566510124 1.7514380822110869 0.0798704780461423 1.0 0.4066294782304713 3 P03886,P00846 2 +Leber optic atrophy 0.9355242566510124 1.7514380822110869 0.0798704780461423 1.0 0.4066294782304713 3 P03886,P00846 2 +Retinal arterial tortuosity 0.9355242566510124 1.7514380822110869 0.0798704780461423 1.0 0.4066294782304713 3 P03886,P00846 2 +Nasogastric tube feeding in infancy 0.6359631515382091 1.749755847514472 0.0801604523724699 1.0 0.4076528221649914 10 P07602,Q9NZJ7,Q9UHX1 3 +Abnormality of coagulation 0.3958113382696966 1.745978369957366 0.0808147104628478 1.0 0.4100697711414936 66 Q9H3H5,Q9Y487,Q10469,Q9BV10,P51571,O75648,P40939,O75352,Q4KMQ2,Q96AA3,P40855,Q7Z2Z2,Q5XKP0,O75340,P56589,Q16836,Q96JX3,P38435,O75381,P15291,P49257 21 +Rhizomelia 0.6061090720190923 1.7413746647058483 0.0816179261651048 1.0 0.4115541080946224 12 Q7RTS9,Q9UBM7,Q15392,Q9BV10,O15228,Q14739 6 +Chronic fatigue 0.70604960795972 1.7362130899902362 0.0825261635748446 1.0 0.4138071245308124 7 P07602,Q9NZJ7 2 +Encephalopathy 0.3456549331228786 1.736108354730005 0.0825446773944047 1.0 0.4138071245308124 109 Q96CU9,Q9H3H5,Q9Y6N5,Q7KZN9,O96000,Q9Y6M9,Q15067,Q9BUB7,O43676,P40939,P03886,Q86Y39,Q8NBU5,Q9NPL8,P00403,Q3ZCQ8,Q9Y276,Q16836,Q9H936,Q86SQ9,Q9Y375,Q96JX3,P03915,P23786,Q9NZJ7,Q9NVI7,P04062,O75306,P07602,Q9NX14,P50416 31 +Recurrent pancreatitis 0.831980549468594 1.7324238213905467 0.083198129675347 1.0 0.4157648738634198 4 P03886,P00403 2 +Abnormality of the intrinsic pathway 0.5729891971431879 1.7323716177720048 0.0832074180123867 1.0 0.4157648738634198 14 Q9H3H5,P38435,Q9Y487,Q9BV10,P49257 5 +Progressive visual loss 0.4846033757060992 1.731521175222611 0.0833588514855974 1.0 0.4160678186350842 26 P50897,O75503,P00846,O14773,O60313,P03915,P03886,Q9NWW5 8 +Hyperkeratosis 0.4006771040977854 1.72897472451882 0.0838136188448013 1.0 0.4173413592416603 57 O75431,P21912,Q9NWM8,P04062,Q06136,O75844,O15269,P42167,P51648,O75352,P98194,P16615 12 +Generalized clonic seizure 0.7955379148288733 1.7257576105801269 0.0843910288001419 1.0 0.4193922928007053 5 Q9NZJ7 1 +Barrel shaped chest 0.7951099982484011 1.723898530132579 0.0847261627348592 1.0 0.4206016009221289 5 Q7RTS9,Q14739 2 +Agenesis of corpus callosum 0.3761624917494978 1.7231514634214713 0.0848611383282549 1.0 0.4208157314069957 82 Q7LGA3,P00403,P53701,Q10713,Q15392,Q86XL3,Q9UHX1,P03915,O95202,Q9HC21,P23786,Q9NX14,P03886,Q5H8A4,Q9H5K3 15 +Epiphyseal stippling 0.5871755895360776 1.721618998714015 0.0851385592805034 1.0 0.4215152379025115 13 P40855,O96011,O75381,Q9UBM7,P38435,P56589,P08236,Q14739,Q15738 9 +Paraplegia paraparesis 0.3710897505937519 1.7213563091789883 0.0851861873194512 1.0 0.4215152379025115 86 P49902,Q96CU9,Q7KZN9,Q9BRK0,Q15041,O75298,Q5XKP0,O60313,P29084,Q9P0J0,P56589,P17302,Q8N0X7,Q9H0B6,P00846,Q6DKK2,P21912,P04062,O75306,P35637,Q13510,Q9H6K4 22 +Abnormality of circulating enzyme level 0.3443204969944438 1.720506600497258 0.0853403949174542 1.0 0.4216663875440283 104 O43505,Q9H3H5,O14979,Q13586,P50402,Q9BUK6,Q9BTV4,Q08J23,P07196,Q9Y6N5,Q9BPX6,P10253,O75648,P40939,P46020,P39210,P13473,P12235,O75340,Q6ZXV5,Q86VD7,Q16836,P22626,Q9H5K3,Q15056,O14653,Q9NWM8,P49748,P23786,O95831,Q3ZAQ7,P15291,Q8NCE2,Q969X5,Q96BR5,P42167,P51530,Q9Y4P3,P50416,P54098 40 +Abnormal circulating citrulline concentration 0.7940200948087914 1.7191622043629116 0.0855848407717037 1.0 0.4216663875440283 5 P03886,P00846 2 +Babinski sign 0.3609576310367678 1.7180775167360007 0.0857824771667181 1.0 0.4217350053489356 93 P49902,Q99720,P07196,Q15067,Q9BRK0,Q8N2K0,P40939,O75298,P41440,Q8WWI5,O60313,Q9NR77,Q9Y4W6,Q8N0X7,Q9UBB4,O43681,Q15043,Q9NZJ7,P00846,O14773,Q6DKK2,P21912,P51812,P07602,P35637,Q9H6K4 26 +Neoplasm of fatty tissue 0.6301147133162153 1.7180754649035737 0.0857828513717171 1.0 0.4217350053489356 10 P03915,Q8TAA9,P21912,Q9BUK6 4 +Lactic acidosis 0.3576346183934774 1.71517537170914 0.086313078822906 1.0 0.4223074657750636 95 Q96CU9,Q9Y6N5,O96000,Q9Y6M9,Q9BUB7,Q9HC21,O43676,O75648,P40939,P03886,Q86Y39,Q9NPL8,Q5XKP0,P39210,P00403,Q6P4A7,P12235,Q86VD7,Q70HW3,Q16836,Q9Y375,Q96JX3,P03915,Q8NI60,Q9NWS8,Q10713,O75306,O43819,Q9NX14 29 +Increased intracranial pressure 0.5191844960826935 1.713609074244353 0.086600545891299 1.0 0.4223074657750636 18 P07602,Q9NZJ7,P21912 3 +Abnormal epidermal morphology 0.5195472598371825 1.7128172349702977 0.0867461683649386 1.0 0.4223920759278946 17 Q06136,O75844,P17302,O75352,P98194,P16615 6 +Tetraplegia tetraparesis 0.4021327290894786 1.7110498874314175 0.0870719038888112 1.0 0.4235280930133048 48 Q7RTS9,Q9UBX3,P00846,P21912,P51572,P07602,Q9NZJ7,P17900,Q13423 9 +Developmental regression 0.3414871767398084 1.7102364093547158 0.08722216547555 1.0 0.4238090797550057 132 Q8NBM4,O95298,Q15067,Q9H9P8,P55795,P03886,O95470,Q96IX5,Q13144,P40855,O75503,P56589,Q86VD7,Q9NZ08,P17900,Q9H936,Q86SQ9,Q15056,Q96JX3,P13073,P03915,O43681,Q8NI60,Q15043,Q9NZJ7,O95831,Q5JPH6,O96011,P00846,O14773,O75381,P21912,P49770,O75306,O95169,P07602,O43819,Q96DA6,Q9Y4P3,Q13510,Q08209,P54098,O76024 43 +Clonic seizure 0.7485810044267007 1.7091181411657017 0.0874290678503242 1.0 0.4243643950107899 6 Q9NZJ7 1 +Thoracic kyphosis 0.5181256393595869 1.7062387238985115 0.0879636416053251 1.0 0.4260564543716698 18 Q7RTS9,P04062,Q10469,P29084,Q9UHX1,P51648 6 +Upper limb spasticity 0.6993177008207293 1.7036810910953697 0.0884406826083572 1.0 0.4264533084365883 7 Q8N0X7,Q99720 2 +Axial dystonia 0.844180225281618 1.7031929076257664 0.088531973512659 1.0 0.4264533084365883 2 Q99720 1 +Type i transferrin isoform profile 0.6273363866666641 1.7029904955077206 0.0885698470932134 1.0 0.4264533084365883 10 Q9H3H5,Q9H0U3,Q9BT22,O75340,P51571 5 +Meningocele 0.6270606356928555 1.701492077653485 0.0888506242146889 1.0 0.4264533084365883 10 Q10713,O75845,P21964 3 +Absent septum pellucidum 0.4397837156313263 1.699284656268092 0.089265562189776 1.0 0.4265013617868129 33 Q9NX14,P53701,Q15392,O95202,P51571,Q96N66,Q9NZ01,Q9H5K3 8 +Furrowed tongue 0.7452392872947449 1.693901389151142 0.0902840229550063 1.0 0.4304697119457223 6 P21912 1 +Profound global developmental delay 0.5666196523079544 1.6931217372594185 0.0904322974889773 1.0 0.4307284689131954 14 P40855,Q9H490,O75381,O60313,P37268 5 +Elevated serum acid phosphatase 0.8219600085756553 1.6903762381751517 0.0909559980468945 1.0 0.4318760446123015 4 P07602,Q9NZJ7 2 +Abnormal peripheral nervous system morphology 0.3248466734850693 1.689057141394832 0.0912084800723891 1.0 0.4319944691930508 166 Q9H3H5,Q16637,Q99720,Q9BV10,Q9BPX6,Q15067,Q9HC21,Q8N2K0,P03886,P41440,P40855,P39210,P00403,Q8IV08,O60313,Q9NR77,O15269,P12235,O75340,Q8TB36,Q9BQT8,P51798,Q9UBB4,Q9UHX1,P03915,O43681,Q15043,Q9NZJ7,Q9NVI7,Q9H0B6,P00846,Q6DKK2,O75381,P21912,P51812,O43819,P07602,P51530,Q13510 39 +Abnormal size of the clitoris 0.5331162459062375 1.6887686108830988 0.0912637813572398 1.0 0.4319944691930508 16 P40855,O96011,O75381,Q9UBM7,P53701,Q96GM8,P56589,Q9NX14,P16435 9 +Proportionate short stature 0.4325329843081272 1.685150714664843 0.0919594971149548 1.0 0.4333214674017674 34 Q7RTS9,P21912,P10619,P53701,Q15392,P40939,Q14739,Q16836 8 +Cerebral inclusion bodies 0.5809773074919544 1.6846852174617273 0.0920493200618601 1.0 0.4333214674017674 13 P04062,O15118,Q9Y287 3 +Abnormal circulating long chain fatty acid concentration 0.7427944862155437 1.6827563680390538 0.0924222647158483 1.0 0.4343372481312997 6 P40855,O96011,O75381,P56589,P23786 5 +Aortic valve calcification 0.9161684269257008 1.6740295556159133 0.0941247908680971 1.0 0.4384994226590937 3 O75844 1 +Abnormality of the larynx 0.4011411344912441 1.6728498901359958 0.094356850572326 1.0 0.4384994226590937 47 Q9UBM7,Q9UHX1,P21964,P07602,P35637,P16435,Q9NZJ7,Q92804,Q13510,Q14739,Q15165 11 +Functional abnormality of the inner ear 0.3198917509797495 1.6723309120297385 0.09445908730579 1.0 0.4384994226590937 262 Q96CU9,Q8NBM4,P07196,O96000,Q15904,Q9BV10,Q10469,Q9Y6M9,Q15067,O95202,O43676,Q8N2K0,P03886,Q86Y39,O95470,Q7LGA3,Q96AA3,P40855,P41440,Q9NPL8,Q5XKP0,P00403,P55263,P51572,O60313,O75844,Q9NR77,O15269,P12235,P29084,P56589,P17302,Q96HR9,Q9Y276,Q9NZ08,Q9H5K3,Q9H061,Q86SQ9,Q9Y375,Q96JX3,Q9NWM8,Q9UG56,P03915,O43681,Q15043,Q2TAA5,Q9NZJ7,O15460,Q9H1P3,Q9NQH7,P42892,P00846,O75381,Q9UBM7,P21912,P04062,P51812,O75306,P07602,P42167,P35637,Q9Y4P3,Q13510,Q9NX14,Q9NR28 65 +Leukoencephalopathy 0.353008020711677 1.6718189719128498 0.0945600245541291 1.0 0.4384994226590937 96 Q96CU9,O95298,O96000,Q9Y6M9,Q9BUB7,O95202,P51571,O43676,O75648,P03886,Q86Y39,Q13144,O75503,Q9NPL8,O60313,P29084,P17900,Q9UHX1,O43681,Q9NZJ7,P07602,Q9NX14,Q9NWW5,Q01105 24 +Peripheral hypermyelination 0.8369837296620795 1.6709277779948757 0.0947359440133206 1.0 0.4384994226590937 2 Q9NR77 1 +Neurofibrillary tangles 0.8171383174515758 1.6700989063216811 0.094899796513092 1.0 0.4384994226590937 4 O15118,Q9Y287 2 +Cutaneous photosensitivity 0.496256806700124 1.6685901777138363 0.0951986268001454 1.0 0.4384994226590937 22 P14324,Q9UBM7,P29084,P22830,P17302,P36551,Q14108,P37268,Q06136 9 +Abnormality of the 5th toe 0.6456190129773793 1.6685067691468198 0.095215169297548 1.0 0.4384994226590937 8 Q7Z4L5,Q14739,Q10713,Q96J42 4 +Postaxial foot polydactyly 0.6456190129773793 1.6685067691468198 0.095215169297548 1.0 0.4384994226590937 8 Q7Z4L5,Q14739,Q10713,Q96J42 4 +Abnormal circulating copper concentration 0.7817566648993818 1.6657484633496211 0.0957635248503985 1.0 0.440550673558761 5 Q9Y487,O43819 2 +Decreased absent ankle reflexes 0.5122244713496907 1.6621662804633068 0.0964794389331806 1.0 0.4429546985890119 17 Q96RL7,P07196,O60313,P12235,Q9H6K4,P54098,Q15041,Q9Y223 8 +Calcinosis 0.7800513146274021 1.658303486441229 0.0972562256723543 1.0 0.4453357795232608 5 O75844 1 +Abnormal circulating non proteinogenic amino acid concentration 0.6893683363716886 1.6554242082471895 0.0978384787884241 1.0 0.4453357795232608 7 P03886,P00846 2 +Abnormal liver physiology 0.736457206763974 1.6538186339712346 0.0981643686858344 1.0 0.4453357795232608 6 Q13510 1 +Recurrent paroxysmal headache 0.5907397970169495 1.6527275882328898 0.0983863170257381 1.0 0.4455323232259424 12 P03886,P21912,P00403 3 +Degeneration of the lateral corticospinal tracts 0.7357470914892349 1.6505717726149451 0.0988260466538528 1.0 0.4455323232259424 6 O75298 1 +Severe global developmental delay 0.3830116023495704 1.6500803384338147 0.0989265055485923 1.0 0.4455323232259424 71 P40855,Q7RTS9,Q9H490,O75381,P00846,Q9BT22,Q96A33,Q9BV10,Q15067,O75340,P03915,Q9HC21,P03886,Q5H8A4,Q7LGA3 15 +Intracellular accumulation of autofluorescent lipopigment storage material 0.91017214397496 1.649984175686828 0.0989461726539353 1.0 0.4455323232259424 3 Q9NWW5,O14773 2 +Decreased ldl cholesterol concentration 0.8115194892413287 1.6464337880019588 0.0996744815081605 1.0 0.4477534061474426 4 Q15800 1 +Dysarthria 0.321770281789382 1.6444682366015624 0.1000795201607749 1.0 0.4482621346314492 167 Q96CU9,Q7KZN9,P07196,O43292,O15020,Q8N2K0,Q13144,P41440,O75503,Q8WWI5,Q5XKP0,Q8IV08,P29084,P12235,Q9P0J0,O15118,P17302,Q14108,P51648,Q5T8D3,Q9Y4W6,Q8N0X7,P15586,O14653,Q9UBB4,O75027,P18887,O43681,Q9NZJ7,Q9H0B6,P00846,O14773,Q6DKK2,P04062,Q10713,P49770,O75306,O43819,P07602,P35637,Q9Y4P3,Q9H6K4 42 +Dysmetria 0.3918940407928891 1.6419437494041311 0.1006016620461693 1.0 0.4495049463957172 59 Q9BUK6,O43292,O15020,Q8N2K0,P41440,O75503,Q9NPL8,Q9C0E8,Q8IV08,O60313,Q6P4A7,Q5T8D3,Q9Y4W6,Q8N0X7,Q9UBB4,O75027,P18887,Q6DKK2,O14773,Q10713,Q9Y4P3 21 +Abnormality of the clitoris 0.5052280594313429 1.6411646733961236 0.1007632366837487 1.0 0.4495049463957172 19 P40855,O96011,O75381,Q9UBM7,P53701,Q96GM8,P56589,Q9NX14,P16435 9 +Death in infancy 0.3890828187377744 1.6390451326934412 0.1012038605549314 1.0 0.4505653340497962 63 P40855,Q9NWS8,Q9NXE4,O75381,P04062,Q9BT22,Q15904,Q6NUK1,Q9BUB7,Q15067,O43819,P56589,P07602,Q9HC21,Q9NZJ7,P20674 16 +Abnormality of the distal phalanges of the toes 0.7750126797899926 1.6362826080060675 0.1017804543295555 1.0 0.4518973272655265 5 O75431,O75844,Q7LGA3 3 +Pes cavus 0.3419815647240683 1.6326237081103967 0.1025481618462884 1.0 0.4548651283443308 101 Q9BUK6,Q99720,P07196,O75648,Q9BRK0,Q8N2K0,P40939,Q14739,O75298,Q7LGA3,P39210,O60313,Q9NR77,O15269,P29084,Q8TB36,Q8N0X7,Q8NI60,Q9H0B6,P04062,Q10713,P05023,Q9H6K4 23 +Emg abnormality 0.3690740536868998 1.6304709320017314 0.1030020038559083 1.0 0.4559953446065428 82 Q9H3H5,Q13586,Q16637,P50402,Q9BUK6,Q9BTV4,Q9Y5L0,P07196,Q96RL7,P39210,P13473,O60313,Q9NR77,O15269,P12235,O75340,Q8TB36,P22626,P03915,O43681,Q8NI60,Q9Y6B6,Q9NZJ7,O14773,Q8NCE2,Q969X5,P07602,P42167,O43819,Q13510,P54098 31 +Microcornea 0.4320239554660265 1.6281822059824504 0.1034862566598686 1.0 0.4576969382389171 33 O43505,O75845,Q9NWM8,Q8NCH0,P29084,Q96J42,Q9H5K3 7 +Abnormality of epiphysis morphology 0.3932028796309348 1.626786880427949 0.1037823689826935 1.0 0.4583091546952478 53 P40855,Q7Z2Z2,Q7RTS9,Q7Z4L5,P51798,P38435,O75381,Q9UBM7,P51812,Q8WVQ1,Q9UG56,P56589,O95202,P08236,O15228,Q14739,P16435,Q7LGA3 18 +Psychotic mentation 0.7296629657084089 1.6227185796097272 0.1046495777696998 1.0 0.4615056451787918 6 P03886,P00403 2 +Rod cone dystrophy 0.3962758033594291 1.6207940790758126 0.1050618087620101 1.0 0.4628780843726253 47 P40855,Q9H3H5,Q86SQ9,O75381,P00846,P38435,Q15067,P03915,P56589,Q96HR9,Q9Y276,Q5T8D3,Q8N2K0,P03886 14 +Increased bone mineral density 0.4598194926429104 1.619699913860426 0.1052967547277707 1.0 0.4634675601946644 28 Q13126,P51798,P04062,Q15392,P29084,Q14108,Q15043,Q9Y4P3,Q14739 9 +Symptomatic seizures 0.6818196005078067 1.6186742223400676 0.1055173760275036 1.0 0.4639929145470458 7 P00367,P40939,Q13423,Q16836 4 +Inability to walk 0.3580440651132044 1.6167837966076404 0.1059249582364314 1.0 0.4648928722598935 90 Q96CU9,Q9H3H5,Q9BUK6,Q99720,P07196,O43292,O14949,Q96N66,Q15041,O75503,Q7RTS9,Q9NR77,O15269,P12235,Q8TB36,Q96JX3,Q15043,Q9NVI7,P00846,P21912,P35637,Q13510 22 +Redundant neck skin 0.7277075772073587 1.6137537518518952 0.1065808497015083 1.0 0.4657917356681315 6 O96000 1 +Abnormal 5th finger phalanx morphology 0.8241551939925118 1.6133092075748243 0.1066773471341746 1.0 0.4657917356681315 2 Q9UHX1 1 +Abnormality of the middle phalanx of the 5th finger 0.8241551939925118 1.6133092075748243 0.1066773471341746 1.0 0.4657917356681315 2 Q9UHX1 1 +Maternal diabetes 0.8241551939924893 1.6133092075747224 0.1066773471341968 1.0 0.4657917356681315 2 Q8TAA9 1 +Vitiligo 0.6349246698784101 1.6130221128001063 0.1067397037214181 1.0 0.4657917356681315 8 P03886,P00403 2 +Abnormal transferrin saturation 0.8235294117647045 1.6104955078379384 0.1072897253539819 1.0 0.4660901632911001 2 Q658P3 1 +Emg impaired neuromuscular transmission 0.768709743530569 1.6086870180826185 0.1076847958555196 1.0 0.4660901632911001 5 O75340,Q9H3H5 2 +Ichthyosis 0.4155104398657958 1.6084517297929746 0.1077362799266998 1.0 0.4660901632911001 37 P40855,Q15800,Q13586,Q7Z2Z2,P50402,O96011,Q9BTV4,O75381,P04062,P48449,P29084,P56589,P18074,P51648,P50542,O95470,Q15738 17 +Slow pupillary light response 0.8023450897745823 1.6077145050953925 0.1078977202814597 1.0 0.4660901632911001 4 P07602,Q9NZJ7 2 +Abnormal pupillary light reflex 0.8023450897745823 1.6077145050953925 0.1078977202814597 1.0 0.4660901632911001 4 P07602,Q9NZJ7 2 +Resting tremor 0.4925258188747178 1.6073248406687712 0.1079831278594574 1.0 0.4660901632911001 21 P04062,P12235,P07602,Q9NZJ7,Q9H6K4 5 +Shoulder girdle muscle weakness 0.5970617562524145 1.605768715496321 0.1083247368150959 1.0 0.4660901632911001 11 O14979,Q9Y5L0,P12235,P07602,Q9NZJ7,P54098 6 +Abnormal larynx morphology 0.4636488939451886 1.6057267646162137 0.1083339579226703 1.0 0.4660901632911001 27 P21964,Q9UHX1,P07602,Q13510,Q9NZJ7 5 +Decreased activity of mitochondrial complex iv 0.536790630123041 1.6055541938128524 0.10837189676996 1.0 0.4660901632911001 15 Q9Y2R0,P13073 2 +Somatic sensory dysfunction 0.3369685156415352 1.6054755166087575 0.1083891970576416 1.0 0.4660901632911001 106 Q93063,Q9BUK6,Q8NBM4,P07196,O15020,P61978,Q9BRK0,Q8N2K0,O75298,P41440,P39210,Q8IV08,Q9NR77,O15269,Q8TB36,Q9NZ08,Q8N0X7,Q8NCH0,P18887,Q9Y6B6,Q9NZJ7,O00170,O15460,Q9H0B6,P00846,O14773,O43819,P07602,Q96BR5,Q9H6K4 30 +Abnormality of ocular smooth pursuit 0.4963433299611076 1.6050184209986835 0.1084897507992637 1.0 0.4660901632911001 20 P41440,O14773,Q9UBB4,Q10713,P46977 5 +Mitral stenosis 0.8017035876091836 1.6050035891612646 0.1084930148028355 1.0 0.4660901632911001 4 O75844 1 +Mixed demyelinating and axonal polyneuropathy 0.7676643107978172 1.6041047236143782 0.1086909708742893 1.0 0.4663127608108556 5 P03915,P03886,P00403 3 +Abnormal cardiac ventricular function 0.4871992064884142 1.6007228473084083 0.1094383184550189 1.0 0.4680264262071974 22 P21912,P00403,O75844,P03915,P03886 5 +Abnormal lower limb bone morphology 0.316000709772319 1.6004491430429697 0.1094989805530588 1.0 0.4680264262071974 172 O43505,O75431,Q9Y487,Q15392,Q9BV10,Q10469,O95202,O75648,P40939,Q14739,Q5H8A4,Q7LGA3,Q7Z2Z2,Q7RTS9,Q9NXE4,Q96A33,O75844,P29084,P17302,O75718,Q9H5K3,Q9H936,Q7Z4L5,Q8N0X7,O75845,P51798,P13073,Q9UHX1,Q9NZJ7,Q32P28,Q9UBM7,P04062,P51812,Q10713,P21964,Q969X5,P07602,P08236,Q9NX62,Q13510,Q96J42,P16435 42 +Anasarca 0.8200876095119093 1.595015570543637 0.1107087539320255 1.0 0.4718670715168364 2 Q9H3H5 1 +Abnormality of visual evoked potentials 0.4861110093076126 1.5925396298869254 0.1112635059433171 1.0 0.4718670715168364 22 O75503,Q9H936,P51798,O60313,Q15067,O43681,P07602,Q9NZJ7 8 +Retinal dysplasia 0.6191965379454354 1.59248035047444 0.1112768147594567 1.0 0.4718670715168364 9 Q9NX14,P53701,Q10713,Q9H5K3 4 +Progressive peripheral neuropathy 0.8951486697965463 1.5896192572708163 0.111920653634199 1.0 0.4718670715168364 3 P07602,Q9NZJ7 2 +Vegetative state 0.8951486697965463 1.5896192572708163 0.111920653634199 1.0 0.4718670715168364 3 P07602,Q9NZJ7 2 +Emg decremental response of compound muscle action potential to repetitive nerve stimulation 0.8951248444331172 1.5895233991702038 0.1119422755868182 1.0 0.4718670715168364 3 Q9H3H5 1 +Single fiber emg abnormality 0.8951248444331172 1.5895233991702038 0.1119422755868182 1.0 0.4718670715168364 3 Q9H3H5 1 +Response to drugs acting on neuromuscular transmission 0.8951248444331172 1.5895233991702038 0.1119422755868182 1.0 0.4718670715168364 3 Q9H3H5 1 +Fulminant hepatic failure 0.8942616252466214 1.586050099661769 0.1127279451643781 1.0 0.4735006018136822 3 P40939 1 +Spastic diplegia 0.4805299652057845 1.5859830287697632 0.1127431594453791 1.0 0.4735006018136822 23 P07602,P51648,Q9NZJ7 3 +Dyskinesia 0.3783970642275087 1.5815333359091766 0.1137561429843145 1.0 0.4764448328648349 70 Q9BTV4,Q08J23,Q96RL7,Q9BPX6,Q9ULK4,Q96N66,P03886,P35610,O75569,Q9P0J0,Q9NZ01,Q9H936,Q86SQ9,Q9UBX3,Q9UBB4,P03915,Q15043,P00846,P04062,O75306,O43819,O95169,Q96DA6,Q08209,Q01105 25 +Anteriorly placed anus 0.5924969795408241 1.580011253356644 0.1141042893717099 1.0 0.4768456877155327 11 Q9NX14,P53701,Q6NUK1 3 +Delayed cranial suture closure 0.455070555201872 1.5799608723104537 0.1141158273690445 1.0 0.4768456877155327 28 P40855,O75431,O75381,Q9Y487,Q8NCH0,P51812,O75844,Q32P28,P16435,O75718 10 +Renal tubular dysfunction 0.4054678963870466 1.579374026733692 0.1142502912683731 1.0 0.4768456877155327 41 Q96CU9,P40855,Q9NPL8,Q9Y375,Q9NWS8,P00403,O96000,O75306,Q9Y6M9,P03915,O43819,O43676,Q9NX14,P03886,Q86Y39 15 +Positional foot deformity 0.3434264127089456 1.579211351160309 0.1142875871840141 1.0 0.4768456877155327 98 P49902,Q9Y487,Q15392,Q9BV10,Q8TAA9,O95202,Q9HC21,Q5H8A4,Q8NBU5,Q7RTS9,Q96A33,Q9NR77,Q8TB36,Q9UM00,O75845,Q9NWM8,Q8NCH0,Q9UHX1,Q8NI60,Q9NVI7,Q9UBM7,P21964,Q969X5,P08236,Q96J42,P16435 26 +Hyperlipidemia 0.4549371507723444 1.5788424549597389 0.1143721979047076 1.0 0.4768456877155327 28 P31751,P50402,O75844,P22830,P23786,P50416,P49257,O95470 8 +Echolalia 0.5921613276683615 1.578114903056305 0.1145392150630391 1.0 0.477107894017132 11 Q9NX14,P53701,Q8NFG4,Q9UHX1 4 +Abnormal pleura morphology 0.4699060429552085 1.574162105761137 0.1154499775116506 1.0 0.4790221367548886 25 P14174,Q93063,Q8NBM4,Q8NCH0,Q6NUK1,O15460,P08236,Q8NFG4,Q9NZ08,Q14739 10 +Mitral valve calcification 0.7943849891731188 1.5740445233099785 0.1154771565988679 1.0 0.4790221367548886 4 P04062,O75844 2 +Cardiac valve calcification 0.7943849891731188 1.5740445233099785 0.1154771565988679 1.0 0.4790221367548886 4 P04062,O75844 2 +Abnormal nephron morphology 0.3795570987904941 1.573316995904192 0.1156454358456713 1.0 0.4790221367548886 68 O75431,Q12769,P00846,P00403,Q8NBM4,P61619,P21912,O75306,O43819,P03915,Q14108,Q9Y276,P23786,Q9Y4P3,P03886,O95470,P23458,Q9NQH7 18 +Abnormal large intestine physiology 0.4879194786787751 1.573262810915119 0.1156579767042889 1.0 0.4790221367548886 21 P21964,O43681,P07602,Q9NZJ7,O75298 5 +Abnormal c peptide level 0.8901517552283267 1.569506723764385 0.1165299139981872 1.0 0.4813973946203684 3 P40939 1 +Splenomegaly 0.3609798545751936 1.5691215383570285 0.1166196220053708 1.0 0.4813973946203684 85 P14174,Q8NBM4,Q15904,Q15392,Q14739,Q96A33,O15118,P36551,Q14108,Q9NZ08,P51798,Q658P3,Q9BT22,Q9NZJ7,P04062,Q9H0U3,Q10713,P21964,P07602,P08236,Q13510 21 +Biliary cirrhosis 0.6714195949846908 1.5678568702581843 0.116914539178224 1.0 0.4821803947026305 7 P09601,Q9UJW0,P14174,Q14739 4 +Cerebral calcification 0.4306733678236154 1.5670193308272435 0.1171101732502379 1.0 0.4823066084799873 32 Q9NSD9,O75845,P00403,O60313,P03915,P17302,P23786,P03886 8 +Turricephaly 0.6143779281430095 1.5666867927217112 0.1171879193862397 1.0 0.4823066084799873 9 Q6NUK1,P21964 2 +Areflexia of lower limbs 0.4533898185087108 1.5658618684708718 0.1173809584582707 1.0 0.4823066084799873 28 Q16637,Q13586,P54886,Q96RL7,P07196,O60313,Q9NR77,P12235,Q15067,Q8NCE2,Q9H6K4,P54098,Q15041,Q9Y223 14 +Abnormal heart rate variability 0.7919536358546988 1.5637469592177466 0.1178770049594826 1.0 0.4831059362471818 4 Q9NZJ7 1 +Scrotal hypoplasia 0.4903725512221094 1.5615743699893212 0.1183882912468929 1.0 0.4839028996371665 20 Q8TCJ2,P46977,Q9BV10,Q6NUK1,P16435 5 +Oromandibular dystonia 0.7162520912485602 1.561110589683582 0.1184976599150273 1.0 0.4839182510968408 6 P35637,Q15043,Q99720 3 +Hyperactive patellar reflex 0.6248183590850158 1.5603322513113165 0.1186813857029156 1.0 0.4841615433829654 8 P13073,P21912 2 +Muscle fiber tubular inclusions 0.7910305396047095 1.5598357665169351 0.118798696929812 1.0 0.4841615433829654 4 O75340,Q9H3H5 2 +Proximal amyotrophy 0.5595779272266802 1.5561491395019509 0.1196726323165999 1.0 0.4852543544587797 13 Q16637,O14979,Q13586,P50402,P07196,P35637 6 +Retinal thinning 0.8113266583229277 1.5555799046690613 0.1198080202883447 1.0 0.4852543544587797 2 P51648 1 +Abnormal optical coherence tomography 0.8113266583229212 1.5555799046690322 0.1198080202883515 1.0 0.4852543544587797 2 Q96S66 1 +Photoreceptor layer loss on macular oct 0.8113266583229212 1.5555799046690322 0.1198080202883515 1.0 0.4852543544587797 2 Q96S66 1 +Xerostomia 0.5120265064697035 1.5475747070399988 0.1217247249158219 1.0 0.4892479733020143 16 Q14739,Q15165,Q92804 3 +Abnormal circulating fatty acid concentration 0.4837759839730715 1.542531430899335 0.1229445061462111 1.0 0.4934919853451613 21 P40855,O75431,O75381,P49748,P56589,P23786,O75648,P40939,Q16836,O75880 10 +Prolonged partial thromboplastin time 0.6662055449065981 1.542301098543946 0.1230004421346235 1.0 0.4934919853451613 7 P28288,Q7Z2Z2,P38435,Q9BV10,P49257 5 +Abnormal lower motor neuron morphology 0.5979091557613047 1.5418759528186556 0.1231037405607855 1.0 0.4934919853451613 10 Q13510,Q99720 2 +Focal onset seizure 0.3610489977915651 1.5391607711269828 0.12376505194467 1.0 0.495456927733351 83 Q9UBX3,Q9H3H5,P21912,P00403,P03915,P07602,Q96PU5,Q9NZJ7,Q96N66,Q01105,P03886,Q9NZ01 12 +Aplasia hypoplasia of the lungs 0.4222613689091154 1.5380615863931388 0.1240335572222195 1.0 0.495456927733351 33 Q7Z4L5,Q9H3H5,O96000,O75844,Q6NUK1,Q8TAA9,O95202,Q14739,Q5H8A4 9 +Abnormal brain n acetyl aspartate level by mrs 0.8820760470839512 1.5369694952035131 0.1243007796450283 1.0 0.495456927733351 3 Q9NZJ7 1 +Abnormal brain choline level by mrs 0.8820760470839512 1.5369694952035131 0.1243007796450283 1.0 0.495456927733351 3 Q9NZJ7 1 +Reduced brain n acetyl aspartate level by mrs 0.8820760470839512 1.5369694952035131 0.1243007796450283 1.0 0.495456927733351 3 Q9NZJ7 1 +Abnormal larynx physiology 0.5103025585231067 1.5359496939377848 0.1245507188512604 1.0 0.495456927733351 16 Q13510,Q15165,Q92804 3 +Fasting hyperinsulinemia 0.7853888616170306 1.5359133295186582 0.1245596385006804 1.0 0.495456927733351 4 P40939,Q16836 2 +Abnormal elasticity of skin 0.3801924520268054 1.5348371700022378 0.1248238299727522 1.0 0.4960475185907638 63 Q13126,P38435,Q9NWM8,Q9Y487,O96000,Q8NCH0,O75844,Q9BV10,P04062,Q9UHX1,P51812,Q9Y4P3,Q9NX14,Q6NUK1 14 +Papilloma 0.6070611971127013 1.5274103440771394 0.1266590058586993 1.0 0.500892220273545 9 P16615 1 +Easy fatigability 0.4773133917481266 1.5261545158091716 0.1269713879371443 1.0 0.5011049952868178 22 Q9H3H5,Q13586,P21912,Q9NWM8,P12235,P53007,O75340,Q8NCE2,P61978,O00170,Q53H12,P54098 12 +Pericardial effusion 0.7822510070067197 1.5225945591731609 0.1278601718372325 1.0 0.5031090064982693 4 P04062 1 +Blurred vision 0.707000516970724 1.5184477933058662 0.128901551033671 1.0 0.5039536416297985 6 P03915,P03886,P00846,O75306 4 +Abnormality of the shoulder girdle musculature 0.4302860881073719 1.5179583205630804 0.1290249061322015 1.0 0.5039536416297985 31 Q9H3H5,O14979,P50402,Q9Y487,O60313,P12235,O75340,P07602,Q9NZJ7 9 +Abnormal circulating metabolite concentration 0.2946785922071322 1.516972794466555 0.1292735529401842 1.0 0.5039536416297985 355 O43505,P14174,O14979,O75431,Q9BUK6,O96000,Q15904,P07196,O43676,P03886,Q86Y39,Q7Z2Z2,Q15800,Q8N511,Q5XKP0,P55263,P13473,O75844,Q4J6C6,P56589,P36551,Q9Y276,Q86VD7,P20674,Q9H5K3,Q9NSD9,O14653,Q9NZJ7,P00846,P21912,P21964,P07602,P42167,Q9H3H5,O95298,Q9Y6M9,Q14739,O95470,P40855,P39210,Q9P0J0,Q70HW3,O75845,Q9NWM8,Q9BT22,P03915,P37268,Q969X5,P50402,Q9Y6N5,Q9Y487,Q15392,Q9BV10,P40939,Q13423,P41440,P12235,O75340,Q16836,Q96JX3,Q15043,P23786,Q9NVI7,O75381,P51530,Q9NX14,P49257,O75880,Q96CU9,Q9BPX6,Q9BUB7,O75648,Q9NPL8,P35610,O14678,Q9Y375,Q12769,P51798,P61619,Q658P3,P22830,P00367,Q3ZAQ7,P31751,Q9UBM7,Q9UGP8,P15291,P05023,O75306,O43819,Q9Y4P3,P50416 92 +Dysmetric saccades 0.7058768967638461 1.5132577372402127 0.1302142034043891 1.0 0.5039536416297985 6 O15020,O14773 2 +Shuffling gait 0.5807006341978966 1.5131733412409536 0.1302356339659158 1.0 0.5039536416297985 11 O75844 1 +Abnormality of alkaline phosphatase level 0.4666444772948762 1.5121208520063545 0.130503121088269 1.0 0.5039536416297985 24 Q8N511,O75845,P51798,Q9UJS0,Q96A33,Q96S52,Q92643,Q14739,P22626 9 +Chorioretinal dysplasia 0.6155263720807743 1.511677278048183 0.1306159817318029 1.0 0.5039536416297985 8 O43505,P53701,Q9NX14,Q9H5K3 4 +Foam cells 0.7464482761301259 1.5108123849600124 0.1308362583515012 1.0 0.5039536416297985 5 O75845,Q13510 2 +Abnormal sensory nerve conduction velocity 0.705241482456988 1.510321925565592 0.1309612997144862 1.0 0.5039536416297985 6 P54098,Q9NR77,O15269 3 +Cerebral visual impairment 0.3763644779352393 1.5060233614548122 0.1320611766607906 1.0 0.5039536416297985 65 Q9H490,P00403,P37268,Q96A33,P12235,P03915,Q96N66,Q01105,P03886,Q9NZ01 10 +Generalized hypotonia 0.292891226566057 1.5036274212080332 0.1326773265378142 1.0 0.504020382649992 359 O75431,Q9BUK6,O15020,O14949,O43676,Q86Y39,O75352,P50897,Q8N511,Q5XKP0,Q9C0E8,P55263,P46977,Q4J6C6,Q3ZCQ8,P56589,Q9Y276,Q86VD7,Q9NZ01,Q9NSD9,Q9UBX3,Q86SQ9,O75208,Q8NCH0,P13073,Q9UHX1,Q9NZJ7,P21912,Q10713,P07602,Q9H3H5,Q7KZN9,Q9Y6M9,Q96N66,Q5H8A4,O95470,Q96AA3,P40855,P39210,Q96A33,Q6P4A7,Q9P0J0,Q70HW3,P17900,O75845,Q9BT22,Q01105,Q9Y487,O43292,Q9BV10,O15228,P40939,Q9NR77,P12235,O15118,O75340,Q8TCJ2,Q16836,Q8N0X7,Q96JX3,O43681,P23786,Q9NVI7,Q6NUK1,O75381,P51530,O75880,Q96CU9,Q10469,Q9BUB7,O95202,P51571,O75648,Q13144,P29084,P11117,O14678,P51798,Q9UBB4,Q8NI60,Q92643,Q9NWS8,Q9UBM7,P51812,P15291,O43819,Q53H12,P50416 88 +Multiple joint contractures 0.4783906578582453 1.5024621132349496 0.1329778054627244 1.0 0.504020382649992 21 P41440,Q9H0B6,O75844,P51530,Q15043 5 +Renal dysplasia 0.550701719938829 1.502387052589788 0.132997178169784 1.0 0.504020382649992 13 O43505,Q9H936,Q9NWS8,O75306,O43819 5 +Motor neuron atrophy 0.4695572433771746 1.50156262777394 0.1332101011325055 1.0 0.504020382649992 23 Q16637,Q99720,Q13510,Q92804,Q15165 5 +Thoracic scoliosis 0.5785387061401526 1.5008820294982783 0.1333860769632093 1.0 0.5040663567569865 11 O75844 1 +Left ventricular systolic dysfunction 0.657618607134552 1.5001042870415513 0.1335873906368019 1.0 0.5040663567569865 7 P54098,O75844,P49748,P12235 4 +Abnormal circulating free fatty acid concentration 0.7764558547275997 1.497972953417959 0.1341402776519467 1.0 0.5054529212181084 4 P40939,Q16836,O75431 3 +Morphological abnormality of the pyramidal tract 0.4815531554766504 1.497085987282834 0.1343708854061021 1.0 0.5055177311922742 20 Q15056,P00846,Q9UBB4,O75569,P35637,Q9Y4P3,O95831,O75298 8 +Neonatal death 0.5351232068950939 1.4968277348717502 0.1344380876187325 1.0 0.5055177311922742 14 Q14739,P04062,O96000,Q9NVI7,Q6NUK1 5 +Ectopic anus 0.5497543642395996 1.4966342313931018 0.1344884579492322 1.0 0.5055177311922742 13 Q9NX14,P53701,Q6NUK1 3 +Brushfield spots 0.7425618540557324 1.4936648570497932 0.1352632383011009 1.0 0.508013244176758 5 P40855,O96011,O75381,P56589 4 +Gastrointestinal hemorrhage 0.4392555666511386 1.4931116273761686 0.1354079694217083 1.0 0.5081403078544369 29 Q9UGP8,P21912,Q8NBM4,P49257,Q9UHX1,P21964,Q14739 7 +Difficulty climbing stairs 0.4876142143512091 1.49010043244269 0.1361978305181577 1.0 0.5093249249764331 17 Q9H3H5,P12235,O75340,P40939,Q9H5K3 5 +Middle age onset 0.5759366083522859 1.486071474225351 0.1372602166033585 1.0 0.5113222052655193 11 Q9NZJ7 1 +Abnormal liver morphology 0.3119742418081403 1.4847859179995355 0.1376005433885885 1.0 0.5114852279842699 242 Q96CU9,P14174,Q9H3H5,O75431,Q7KZN9,O96000,Q15904,Q9Y6M9,Q15067,Q9BUB7,Q9HC21,O43676,O75648,P40939,P03886,Q86Y39,Q14739,Q96AA3,Q7Z2Z2,P40855,Q8N511,Q5XKP0,P39210,Q9NPL8,P55263,P09601,Q96A33,P35610,O15118,O75340,P56589,P36551,Q9Y276,Q14108,P20674,Q16836,Q9NSD9,Q7Z4L5,Q86SQ9,Q9Y375,O75845,P51798,Q658P3,Q9BT22,P22830,P03915,P23786,Q9NZJ7,Q9NVI7,P23458,P31751,Q9NWS8,P00846,O75381,Q9UGP8,P04062,P10619,Q9H0U3,Q10713,P50416,O75306,P07602,P08236,Q13510,Q9NX14,Q96J42,Q01844,O75880 68 +Prominent ear helix 0.7706909505551376 1.4734508464075398 0.1406295084939279 1.0 0.5178468296271305 4 O75844 1 +Extrapyramidal muscular rigidity 0.6966438712756813 1.4705427766255967 0.1414148091036819 1.0 0.5181776942871761 6 Q9H6K4 1 +Ambiguous genitalia male 0.8653685943279943 1.4695456836060503 0.1416848403667014 1.0 0.5181776942871761 3 O75845 1 +Abnormality of the ankles 0.3822631161688075 1.4695094762392316 0.1416946534408638 1.0 0.5181776942871761 47 P49902,Q8N0X7,Q7RTS9,O75844,Q969X5,P07602,Q9NZJ7,O75298 8 +Abducens palsy 0.8651770653979094 1.4687720369604536 0.1418946309974567 1.0 0.5181776942871761 3 Q9NZJ7 1 +Pulmonary infiltrates 0.5957742113166505 1.466569465607964 0.1424932114364561 1.0 0.5181776942871761 9 P04062,Q13510 2 +Psychosis 0.4195433160247585 1.4655316472678896 0.1427759245416195 1.0 0.5187940414351316 32 Q8N0X7,Q6DKK2,P00403,Q9UJS0,Q96RL7,P51812,Q9Y287,O15118,P03915,P36551,O00170,P03886,O76024 13 +Spastic paraplegia 0.3787869355766044 1.4631651535862222 0.143422193314856 1.0 0.5199533935206804 52 Q96CU9,P49902,Q8N0X7,Q9H0B6,P00846,P04062,Q7KZN9,Q9P0J0,O75298,Q9BRK0,Q15041 11 +Retinal pigment epithelial mottling 0.8637771267010471 1.4631168099056595 0.1434354189022566 1.0 0.5199533935206804 3 Q9UG56 1 +Hyperextensible skin 0.5145611437437365 1.46110451489278 0.1439867613905594 1.0 0.5215393997561607 15 P04062,Q8NCH0,Q9UHX1 3 +Abnormal circulating proline concentration 0.7669575521780051 1.457555643765458 0.144963063365914 1.0 0.5238334040556926 4 O96000 1 +Depletion of mitochondrial dna in muscle tissue 0.733535716211134 1.4537774920544153 0.146008005656038 1.0 0.526740463535479 5 Q9UBX3 1 +Anomalous trichromacy 0.8607818628876541 1.4510146556963686 0.1467757792725277 1.0 0.5283005660854062 3 Q9H6K4 1 +Tritanomaly 0.8607818628876541 1.4510146556963686 0.1467757792725277 1.0 0.5283005660854062 3 Q9H6K4 1 +Limb muscle weakness 0.3517833277188695 1.4447481426197524 0.1485286419024807 1.0 0.533293047379555 85 Q16637,Q13126,P50402,Q99720,P07196,Q15067,P40939,Q14739,O75298,Q7RTS9,P39210,Q9NR77,O15269,P12235,Q8TB36,P36551,Q8N0X7,Q9BQT8,Q3ZAQ7,P00846,P05023,O43819,Q969X5,Q13510 24 +Talipes equinovarus 0.3623126468276672 1.4443345121798008 0.1486449022149407 1.0 0.533293047379555 75 P49902,Q9Y487,Q15392,Q9BV10,Q8TAA9,O95202,Q9HC21,Q5H8A4,Q8NBU5,Q7RTS9,Q96A33,Q9NR77,Q8TB36,Q9UM00,O75845,Q9NWM8,Q8NCH0,Q8NI60,P21964,Q969X5,P16435 21 +Childhood onset 0.3987367005752306 1.443979416953165 0.1487447652883176 1.0 0.533293047379555 37 Q8N0X7,Q9H3H5,O75431,P50402,O95298,Q9NR77,Q8WWV3,P22830,Q8TB36,Q14566 10 +Positive romberg sign 0.5799833412470946 1.4426055341426256 0.1491316235302342 1.0 0.5342620007940057 10 P41440,P07196,Q8IV08,P18887,Q9H6K4 5 +Laryngomalacia 0.5405589368562035 1.4406515201972063 0.1496831574730524 1.0 0.5353541519301028 13 P07602,P16435,Q9NZJ7,P21964 4 +Motor delay 0.3098789150780466 1.439747988322171 0.1499387111329411 1.0 0.5353541519301028 231 P49902,Q9H3H5,Q9BUK6,Q99720,Q9Y487,Q9BV10,Q9BPX6,O75648,Q96N66,P40939,P03886,Q5H8A4,Q7LGA3,Q7RTS9,Q5XKP0,P00403,P35610,O60313,Q9NR77,P29084,O75340,Q8TB36,Q5T8D3,Q86VD7,Q9UM00,Q16836,Q9NZ01,Q9H5K3,Q8N0X7,P51798,Q9NWM8,Q8NCH0,P03915,Q3ZAQ7,Q9H0B6,P21912,P04062,P51812,Q10713,O43819,P35637,Q13510,Q53H12,P16435,Q01105 45 +Atrophy degeneration affecting the central nervous system 0.3031422414820953 1.4343662510363169 0.1514677733046094 1.0 0.5353541519301028 306 Q9H3H5,Q16637,Q99720,P07196,Q10469,Q9BUB7,O75648,Q96N66,P03886,Q86Y39,O75352,O75298,Q5H8A4,Q7LGA3,P50897,Q96AA3,P40855,O75503,Q8NBU5,P00403,P55263,P51572,Q96A33,O60313,P29084,Q3ZCQ8,O15118,Q9Y276,Q9UM00,P17900,O14678,Q9NZ01,Q9NSD9,Q9H936,Q86SQ9,Q9H490,O75845,Q96JX3,Q9BT22,P13073,Q9UHX1,P03915,Q15043,Q2TAA5,Q9NZJ7,Q15165,Q9NWS8,P00846,O14773,Q6DKK2,O96008,P04062,P51812,Q10713,O75306,O43819,P07602,Q9Y320,P08236,P35637,Q9Y4P3,Q13510,Q92804,Q9NWW5,Q01105,O75880 66 +Rigidity 0.3732623307768659 1.432933281499314 0.1518769049930695 1.0 0.5353541519301028 60 Q96CU9,P00846,P04062,Q15392,Q9BPX6,P12235,O43681,P07602,Q9H6K4,Q9NZJ7,Q9BRK0,Q9Y287 12 +Type i diabetes mellitus 0.5531282540766398 1.4326648659079944 0.1519536346696377 1.0 0.5353541519301028 12 P03886,P00403 2 +Cardiovascular calcification 0.578000646439962 1.431577466529029 0.1522647822751444 1.0 0.5353541519301028 10 O75844 1 +Respiratory insufficiency 0.3063240836745601 1.4290182664039743 0.1529989833806777 1.0 0.5353541519301028 185 Q96CU9,Q9H3H5,Q16637,P50402,O96000,Q9Y6M9,Q15067,Q9BUB7,O43676,O75648,P40939,P03886,Q86Y39,Q14739,Q96AA3,P40855,Q7RTS9,Q9NPL8,Q9NXE4,Q5XKP0,Q8NBU5,P13473,Q9NR77,P12235,P56589,P36551,Q70HW3,Q9H5K3,Q9NSD9,Q7Z4L5,Q9Y375,O75208,Q9BT22,P23786,Q9NZJ7,Q6NUK1,Q15165,Q3ZAQ7,O75381,Q9UGP8,Q53H12,P53701,O75306,O43819,Q969X5,P07602,P35637,Q13510,Q92804,Q9NX14 50 +Color vision defect 0.478395008479997 1.4258463266957973 0.1539127052062718 1.0 0.5353541519301028 18 Q9H061,Q9H6K4,Q8WWV3 3 +Upper airway obstruction 0.7272184770308243 1.4258124436374056 0.1539224880387995 1.0 0.5353541519301028 5 O75844 1 +Abnormal basal ganglia mri signal intensity 0.415135063785215 1.4250950234754078 0.1541297350069987 1.0 0.5353541519301028 32 Q96CU9,P00846,Q7KZN9,Q9BPX6,Q9P0J0,O75340,P03915,Q8NI60,P03886 9 +Abnormality of lower limb joint 0.3112056057875607 1.42476763003521 0.1542243822394737 1.0 0.5353541519301028 165 P49902,Q9H3H5,O75431,Q9Y487,O95202,O75298,Q15041,Q7LGA3,Q8NBU5,Q7Z2Z2,Q7RTS9,Q96A33,O75844,Q9NR77,O75340,P17302,O75718,Q8N0X7,P51798,Q86XL3,Q9UHX1,Q96PU5,Q15043,P23786,Q9NZJ7,P37268,Q9UBM7,P21912,P21964,Q969X5,P07602,P08236,Q9NX62,Q9Y4P3,Q13510,P16435 36 +Abnormal enzyme coenzyme activity 0.3068902992753718 1.422179305885834 0.1549742047122408 1.0 0.5353541519301028 193 O43505,Q9H3H5,O75431,Q15904,Q10469,Q9BV10,Q15067,O75648,P40939,P03886,Q14739,Q14566,P41440,Q7Z2Z2,P40855,Q8N511,Q5XKP0,P39210,P55263,Q96A33,P12235,O15118,O75340,Q9Y276,O14678,P20674,Q16836,Q9H5K3,Q9NSD9,O75845,P51798,Q658P3,P03915,Q92643,P23786,Q9NZJ7,Q2TAA5,P00846,P04062,P10619,Q10713,P07602,Q13510,P50416,O75880 45 +Pathologic fracture 0.4778411882911672 1.421887786416257 0.1550588293746821 1.0 0.5353541519301028 18 O75845,Q13126,P04062,O15269,Q14108,P22626 6 +Flat occiput 0.5082880769141493 1.420014529296295 0.1556034512079769 1.0 0.5353541519301028 15 P40855,O96011,P52732,O75381,Q9BUB7,P56589 6 +Lower limb pain 0.6855738557322264 1.4191805501705244 0.1558463848826523 1.0 0.5353541519301028 6 Q8WVX9,P00846,O75569,P54886 4 +Abnormal autonomic nervous system physiology 0.3988760825015318 1.4181858890693195 0.1561365005590627 1.0 0.5355427678260657 35 P42892,P41440,P04062,Q15067,P07602,Q9NZJ7 6 +Lumbar hyperlordosis 0.4738565964691398 1.415476233069184 0.1569289120342991 1.0 0.5378072363060274 19 Q7RTS9,Q9H3H5,Q9H5K3 3 +Abnormal urine protein level 0.3730058621228536 1.4144945697819695 0.1572167406473192 1.0 0.5382979176538463 57 P00403,P09601,P21912,P04062,Q14108,P03886,O95470 7 +Waddling gait 0.4541477133261789 1.4136702635779892 0.1574587402786498 1.0 0.5382979176538463 24 Q7RTS9,Q9H3H5,P50402,Q9BTV4,P07196,Q8WVQ1,Q4J6C6,O75340,Q5T8D3,Q13510 10 +Generalized osteosclerosis 0.8508261452287129 1.4107690825893622 0.1583127136089053 1.0 0.5405282069716871 3 Q15392 1 +Peripheral neuropathy 0.3039914683831192 1.4073166578128384 0.1593335119920056 1.0 0.5429130923536963 176 Q96CU9,Q9Y2R0,Q7KZN9,Q9BPX6,Q15067,Q9HC21,Q8N2K0,P40939,P03886,Q15041,O95470,P41440,Q9NPL8,P39210,P00403,Q8IV08,O60313,Q9NR77,O15269,P12235,Q9P0J0,P29084,Q8TB36,Q16836,P03915,O43681,Q9NZJ7,Q9NVI7,O15460,Q9NWS8,Q9H0B6,P00846,Q10713,P05023,O75306,P07602 36 +Facial capillary hemangioma 0.8491392801251925 1.4039474776766987 0.1603344902558627 1.0 0.5438207909433305 3 P16435,Q10469 2 +Avascular necrosis 0.4687750988666211 1.40300901073559 0.1606141519736827 1.0 0.5443299144551882 20 P51798,Q8NBM4,P04062,O75844,Q14108 5 +Glomerular sclerosis 0.397208895044491 1.4019641758045152 0.1609259446788307 1.0 0.5449835022308961 35 Q12769,P00403,P61619,P21912,P03915,Q14108,P03886,O95470 8 +Slender long bone 0.5340969582937144 1.4011599623207724 0.1611662439999504 1.0 0.5452492325886751 13 Q9Y487,P37268,Q9H490,Q32P28 4 +Status epilepticus 0.3736294591972354 1.4008936631362734 0.161245874008663 1.0 0.5452492325886751 49 Q9Y487,O43292,Q15392,P52732,Q12756,Q3ZCQ8,Q86SQ9,Q9UBB4,Q9NZJ7,P42892,P53701,P05023,P07602,Q96S52,Q13510,Q9NX14,Q08209,P51970,Q01105,P54098 20 +Adipose tissue loss 0.5834168341192945 1.399628951788506 0.1616244595462532 1.0 0.5453337802952375 9 O75844,P29084 2 +Hyporeflexia of upper limbs 0.8474673708287458 1.397185780678578 0.162357711530352 1.0 0.5458120438558638 3 Q15067 1 +Glucose intolerance 0.3237554673467515 1.3971721464293323 0.162361810514086 1.0 0.5458120438558638 108 Q96CU9,O75431,O96000,Q9Y6M9,Q8TAA9,O43676,P03886,Q06136,Q86Y39,Q7Z2Z2,Q9NPL8,Q9NXE4,P00403,O60313,O75844,P12235,P17302,Q96HR9,Q9Y375,P03915,P31751,P00846,O75306,Q9Y4P3,Q9NX14 25 +Atrophic scars 0.6366852327974417 1.3967076831564973 0.1625014928171493 1.0 0.5458811144341482 7 Q8NCH0 1 +Abnormal pulmonary interstitial morphology 0.4116798809918277 1.3933092274911394 0.1635263014748722 1.0 0.5481960624267606 32 P09601,Q14108,P04062,Q13510 4 +Hypolipoproteinemia 0.5926815879898115 1.391261714206864 0.164146079071686 1.0 0.5492596804976209 8 Q15800 1 +Epileptic spasm 0.3672207071992682 1.38847930508457 0.1649911422174539 1.0 0.549448678608324 64 Q9UBX3,Q9H3H5,P00846,P13073,P03915,Q13510,Q96N66,Q01105,P03886,Q9NZ01 10 +Abnormal adipose tissue morphology 0.3694245800282073 1.388020001766407 0.165130954533158 1.0 0.549448678608324 60 P31751,Q9H3H5,O75431,P50402,Q9BUK6,Q9BTV4,Q9Y487,P21912,O75844,Q9BV10,P29084,P03915,Q8TAA9,P42167,Q8NFG4,Q2TAA5,Q8NC56,Q6NUK1 18 +Impaired smooth pursuit 0.5034048271117475 1.3879349775176733 0.1651568457653707 1.0 0.549448678608324 15 P41440,Q9UBB4,Q10713,P46977 4 +Abnormality of the phalanges of the toes 0.5177237488850885 1.386924520630255 0.1654647798976072 1.0 0.5497894282022018 14 Q9H936,O75431,O75844,Q7LGA3 4 +Loss of subcutaneous adipose tissue in limbs 0.7502705702286294 1.3863873911407032 0.1656286444995627 1.0 0.5499351080413016 4 O75844 1 +Insidious onset 0.7496958355779085 1.3839330705018649 0.1663789494480041 1.0 0.5508287123483864 4 P04062,Q9NR77 2 +Cystic liver disease 0.5903905913039972 1.37912819052389 0.1678552334831908 1.0 0.5508287123483864 8 Q7Z4L5,P23458,Q96J42 3 +Abnormal macular morphology 0.4311051969069076 1.3772904159929056 0.1684224771487585 1.0 0.5508287123483864 28 P50897,Q86SQ9,P04062,P29084,Q96HR9,P51648,Q9UM00,Q13510,P04439 9 +Supernumerary tooth 0.6764290041228275 1.3766395694920008 0.168623710702467 1.0 0.5508287123483864 6 Q9UHX1 1 +Purpura 0.4714997515143929 1.3764712085130462 0.1686757951627659 1.0 0.5508287123483864 18 P04062,Q8NCH0,P21964 3 +Progeroid facial appearance 0.6325345577667362 1.3761249325047378 0.1687829576903392 1.0 0.5508287123483864 7 O75844 1 +Skin plaque 0.7157329947260423 1.3748773609560645 0.1691694690205496 1.0 0.5513047703073674 5 P16615 1 +Slow decrease in visual acuity 0.5671725043800302 1.3711917627640486 0.1703151853291498 1.0 0.5543069802967542 10 P03886,P00846 2 +Parkinsonism 0.4042129094149249 1.3695997547423406 0.1708118762174253 1.0 0.5550780261193211 33 O96008,Q99720,P04062,O75569,P07602,P35637,Q15043,Q9NZJ7,P54098,Q9Y4W6 10 +Cerebral hypomyelination 0.5143831959717429 1.3657160133014778 0.1720281162125259 1.0 0.5566616020379899 14 P51572,O43175,P49770,O75340,P00387,Q9NR50,O75746,Q13144 8 +Gaze evoked nystagmus 0.5758460579628288 1.3584599080874074 0.174317795893141 1.0 0.5612959527634379 9 P41440,Q9UBB4,Q10713,O15020 4 +Atrophy degeneration affecting the cerebrum 0.30579497257282 1.3556318681148447 0.1752163269924347 1.0 0.5630022512477811 241 Q9H3H5,Q9BUB7,O75648,Q96N66,P03886,O75352,Q5H8A4,Q7LGA3,P50897,Q96AA3,P40855,O75503,Q8NBU5,P00403,P55263,P51572,Q96A33,O60313,P29084,Q3ZCQ8,Q9Y276,Q9UM00,P17900,O14678,Q9NZ01,Q9NSD9,Q9H936,Q86SQ9,Q9H490,O75845,Q9BT22,P13073,Q9UHX1,P03915,Q15043,Q2TAA5,Q9NZJ7,Q9NWS8,P00846,O14773,Q6DKK2,O96008,P04062,P51812,Q10713,P07602,Q9Y320,Q9Y4P3,Q9NWW5,Q01105 50 +Epidermal acanthosis 0.5857433229457859 1.35448582832998 0.1755814316571062 1.0 0.5637800419431401 8 P16615 1 +Increased serum pyruvate 0.391725473223081 1.348467575375348 0.1775080422068187 1.0 0.5687705240501002 35 Q96CU9,Q9NPL8,Q9Y375,P21912,O96000,Q9Y6M9,O43676,Q70HW3,Q9NX14,P03886,Q86Y39 11 +Abnormality of corneal size 0.3750951443706075 1.3451974466884775 0.1785614805654944 1.0 0.5713468603010444 45 O43505,O75845,Q9NWM8,Q8NCH0,P29084,O95202,Q9Y4P3,Q96J42,Q5H8A4,Q9H5K3 10 +Recurrent aspiration pneumonia 0.6694216940639216 1.3439813461472152 0.1789544190673231 1.0 0.5722045695509244 6 P04062,Q13510 2 +Basal ganglia cysts 0.6254246516750384 1.3408117459203863 0.1799815816309347 1.0 0.5731500135708574 7 P00846 1 +Congenital hepatic fibrosis 0.7079735102675355 1.340407860188533 0.1801127816900072 1.0 0.5731500135708574 5 Q10713 1 +Nonprogressive 0.6252032333959292 1.3397109332356376 0.1803393416589018 1.0 0.5731500135708574 7 Q10713 1 +Hydrocephalus 0.3519882864318381 1.339234161798187 0.1804944544460589 1.0 0.5731500135708574 77 Q15392,Q8TAA9,O95202,P40855,Q9H5K3,Q9H490,P51798,P23786,Q6NUK1,Q9UBM7,P04062,P53701,Q10713,P15291,P21964,P08236,Q9NX14,Q96J42,P16435 19 +Dyschromatopsia 0.5828668775593984 1.339214124755006 0.180500975465462 1.0 0.5731500135708574 8 Q9H061,O60313,Q9H6K4 3 +Abnormal tricuspid valve morphology 0.5500143569276836 1.3375925087301557 0.1810293077920539 1.0 0.5738176805493926 11 Q9NX14,P53701,P21964 3 +Limb joint contracture 0.3271359438291852 1.336905235097111 0.1812535717864776 1.0 0.5738176805493926 98 P49902,Q9H3H5,P50402,Q99720,Q15392,Q9BUB7,Q9HC21,Q8N2K0,Q7LGA3,O75844,Q9NR77,O75340,Q86XL3,P23786,P37268,P42892,P21912,Q969X5,P16435 19 +Abnormal bone structure 0.3017549049276787 1.3364530776792012 0.1814012275229712 1.0 0.5738176805493926 186 Q9H3H5,O75431,Q13126,Q93063,Q9Y487,O43292,Q15392,Q9BV10,Q10469,O95202,Q9HC21,P61978,O15228,Q14739,Q5H8A4,Q7Z2Z2,P40855,Q7RTS9,O75844,P29084,P12235,P56589,P17302,Q14108,O75718,P22626,Q9NSD9,Q15056,Q9Y5U9,Q9H490,O75845,P38435,Q9Y375,Q9NWM8,P51798,Q8WVQ1,Q86XL3,Q9UG56,O60566,Q15043,Q9NZJ7,O00170,O95831,Q6NUK1,Q32P28,O75381,Q9UBM7,P21912,P04062,P07602,P08236,Q8NC56,Q13510,Q5JRA6,Q9Y4P3,P53634 56 +Hemianopia 0.5821846098211374 1.3355897181720389 0.1816834126308801 1.0 0.5738176805493926 8 P03886,P00403 2 +Abnormality of the tonsils 0.6237340379393245 1.3324050266752292 0.1827271312226575 1.0 0.5754334812798739 7 P31751,Q13546,P21964 3 +Small intestinal dysmotility 0.7615769712140137 1.3312024813274008 0.1831223951795211 1.0 0.5755329647288099 2 P36551 1 +Retinal coloboma 0.548836465465874 1.330808299780188 0.1832520962779662 1.0 0.5755329647288099 11 Q9UHX1 1 +Abnormal protein o linked glycosylation 0.8310523624317073 1.3307807877120286 0.1832611513617053 1.0 0.5755329647288099 3 Q8N511 1 +Cytochrome c oxidase negative muscle fibers 0.5806560182675264 1.3274665364523388 0.1843544024179078 1.0 0.5777782981387507 8 O00483,Q9Y2R0,O75648,P12235 4 +Falls 0.5697798280964158 1.3253924786312 0.185041010348633 1.0 0.5791379162687409 9 Q5T8D3,P21912 2 +Pericarditis 0.6649636026193138 1.3231791614267432 0.1857758042115582 1.0 0.5809606143189231 6 O15460,P14174,Q8NBM4 3 +Hiatus hernia 0.569267060592838 1.3225942487382616 0.185970347874586 1.0 0.5809606143189231 9 Q8NCH0 1 +Clonus 0.403811814083984 1.3206393510840158 0.1866216452941891 1.0 0.5816867003808011 32 Q8N0X7,Q8WWI5,Q9BQT8,Q99720,Q3ZCQ8,P07602,P35637,Q15043,Q9NZJ7,O75298,Q9H5K3 11 +Osteoarthritis 0.5470082474555927 1.3202725769101158 0.1867440279921777 1.0 0.5816867003808011 11 P04062,Q14108,O75844,P51798 4 +Insulin resistant diabetes mellitus 0.6641700782234254 1.3194745591459298 0.1870105099144268 1.0 0.5820309119870046 6 P31751,O75844 2 +Abnormal tendon morphology 0.3038139597267131 1.3191810729134703 0.1871085843205713 1.0 0.5820309119870046 222 P49902,Q9H3H5,O75431,P50402,Q99720,P07196,Q15392,Q9BV10,Q9BUB7,Q9HC21,O15228,Q8N2K0,O75352,Q15041,Q7LGA3,P50897,Q96AA3,Q7RTS9,P41440,Q9NXE4,Q8NBU5,Q96A33,O60313,O75844,Q9NR77,P29084,O75340,P17302,Q8TB36,Q9H5K3,Q8N0X7,P15586,Q8NCH0,Q9BT22,Q86XL3,Q96PU5,Q15043,P23786,P37268,Q3ZAQ7,P42892,Q9H0B6,P21912,P04062,Q969X5,P51530,P08236,P35637,Q13510,P16435 50 +Macroglossia 0.3987799237111474 1.3184511828279617 0.1873526566538461 1.0 0.5823947576580211 33 Q15056,P21912,Q96A33,O00170,Q10713,P10253,O75648,P61978,Q9Y4P3,Q9H5K3,Q7LGA3 11 +Abnormality of the spleen 0.3191045259784951 1.3167380172619143 0.1879264556296846 1.0 0.5831868124472346 118 P14174,Q8NBM4,Q15904,Q15392,O95202,Q14739,Q96A33,O15118,P36551,Q14108,Q9NZ08,O75845,P51798,Q658P3,Q9BT22,Q9NZJ7,P23458,P04062,P10619,Q9H0U3,Q10713,P21964,P07602,P08236,Q13510,Q96J42 26 +Amyotrophic lateral sclerosis 0.4628915923851537 1.3146227302647493 0.188636727021521 1.0 0.5844039778313789 17 Q15165,Q92804,Q99720 3 +Cogwheel rigidity 0.6200004263910406 1.3138266777155532 0.1889045377731713 1.0 0.5848382378896424 7 P00846 1 +Increased muscle lipid content 0.5669179323315583 1.3097688288202316 0.1902740511449012 1.0 0.5866996651049378 9 Q9BUK6,Q8NI60,P23786,O75648,Q9Y4W6 5 +Abnormal circulating pyruvate family amino acid concentration 0.4447116093748746 1.3081743722224424 0.1908141724014791 1.0 0.5876382185728165 23 Q5XKP0,P00846,O95298,O96000,Q9P0J0,P03915,P03886,O75880 8 +Abnormal circulating ferritin concentration 0.6617371938153076 1.30811314855828 0.1908349343597448 1.0 0.5876382185728165 6 P41440,P36551,Q658P3 3 +Abnormality of the knee 0.3394154723717163 1.3057615637953532 0.1916336547469483 1.0 0.5893056416446426 87 P49902,Q9H3H5,O75431,Q15041,Q7LGA3,Q7RTS9,Q9NR77,O75340,Q8N0X7,P51798,Q86XL3,Q96PU5,P23786,P37268,P21912,P21964,Q969X5,P08236,Q9NX62,Q9Y4P3,Q13510 21 +Narrow jaw 0.7553191489361661 1.302990621879236 0.1925779632900646 1.0 0.5908574073643572 2 O75909 1 +Spinal deformities 0.7307451471509077 1.302919956791252 0.1926020898679679 1.0 0.5908574073643572 4 Q8TB36,Q93063,P53007 3 +Wide anterior fontanel 0.4480412365096889 1.3025492970224295 0.1927286774572492 1.0 0.5908574073643572 22 P40855,O96011,O75381,Q16134,Q08J23,Q9Y487,Q6NUK1,P56589,P42345,Q32P28,P20674,P16435,O75718 13 +Hypopigmentation of the skin 0.3689792179086201 1.301183794833193 0.193195550794202 1.0 0.5913306705003565 46 P53701,P21964,Q9NZJ7,P21912 4 +Abnormal periventricular white matter morphology 0.380912479327415 1.295282171010526 0.1952229073197389 1.0 0.5943528861585834 39 O75503,O95298,O60313,Q9UHX1,O43681,P07602,O95202,P51571,O75648,Q9NZJ7,P17900 11 +Ulnar claw 0.6977912401762436 1.2951176264276258 0.1952796552289424 1.0 0.5943528861585834 5 Q8TB36,P39210,Q9NR77 3 +Abnormality of the musculature of the lower limbs 0.4307747780612886 1.2944781032657533 0.1955003279585738 1.0 0.5943528861585834 26 O14979,P00846,P50402,Q9BTV4,Q12756,Q96RL7,P07196,Q9NR77,P53007,Q8NCE2,Q9Y223,Q9H5K3 12 +Congenital onset 0.3175185676456797 1.2934101539958869 0.1958692400915453 1.0 0.5943528861585834 112 O43505,Q9H3H5,Q9BUB7,Q9HC21,P51571,P08670,Q96N66,O75352,Q5H8A4,Q7LGA3,Q8NBU5,Q5XKP0,P46977,Q4J6C6,P12235,P17302,O14678,Q8TCJ2,Q9H5K3,Q9UHX1,Q96PU5,Q9NZJ7,Q6NUK1,Q9NWS8,O43819,Q969X5,P07602,Q9NX14 28 +Nasal regurgitation 0.7525031289111347 1.2903011170893095 0.1969461291974101 1.0 0.5968301349090829 2 P53007 1 +Talipes calcaneovalgus 0.6959660509332941 1.2869934454816303 0.1980965727210923 1.0 0.5988116762595902 5 Q9UBM7,Q9NR77 2 +Abnormality of the foot musculature 0.7269179605357425 1.2865434899925492 0.1982534510881271 1.0 0.5988116762595902 4 O14979,Q8NCE2 2 +Nephronophthisis 0.6955442565194778 1.2851157582885184 0.1987518356714239 1.0 0.5999215487789622 5 Q7Z4L5 1 +Atrophy degeneration involving the corticospinal tracts 0.5150756728201786 1.2842549215029069 0.1990527740070933 1.0 0.600220823330234 13 P35637,P00846,O75298 3 +Osteopetrosis 0.7260496141117798 1.2828273792671687 0.1995525596479788 1.0 0.6011504459612353 4 Q15392,P51798 2 +Progressive spastic quadriplegia 0.5720137730189886 1.2814693296873678 0.2000288660325677 1.0 0.601399123465371 8 P17900,P07602,Q9NZJ7 3 +Abnormality of the tongue 0.3303442325457655 1.28085537425158 0.2002444698439145 1.0 0.6016525644752894 93 Q16637,O75431,Q10469,O75648,Q7LGA3,P40855,Q96A33,O75844,Q9H5K3,Q9BQT8,O15460,Q6NUK1,Q9NWS8,O75381,Q9UBM7,P21912,Q10713,Q9Y4P3,Q13510,Q96J42 20 +Acute hepatic failure 0.5005599606718424 1.2776197087257368 0.2013835479025276 1.0 0.6038870526762969 14 P40939,Q16836,P39210 3 +Abnormal visual fixation 0.6546890083614011 1.2751717552414925 0.2022484561370605 1.0 0.6048971449216785 6 P04062 1 +Abnormal circulating glutamine family amino acid concentration 0.6121643277046673 1.2747816420104194 0.2023865402334075 1.0 0.6049152820283583 7 O96000 1 +Pneumothorax 0.5703652996736528 1.2726825890386226 0.2031306983739524 1.0 0.6063484429638112 8 Q8NCH0,Q6NUK1,Q8NFG4 3 +Abnormality of exocrine pancreas physiology 0.4711690683841618 1.2690112464721548 0.2044370529159616 1.0 0.6082731936784184 16 Q7Z2Z2,P14174,P09601,Q15904,Q9UHX1 5 +Neck muscle weakness 0.5123414079238657 1.2673764305780333 0.2050207232827656 1.0 0.6082731936784184 13 P07602,Q9NZJ7 2 +Preaxial hand polydactyly 0.5485899908564158 1.2669965074721694 0.2051565387025751 1.0 0.6082731936784184 10 Q96J42,O95202,Q5H8A4,Q9UHX1 4 +Autoamputation 0.6528797245137565 1.2667097423464715 0.2052590951888842 1.0 0.6082731936784184 6 P39210 1 +Visual hallucinations 0.6528369311008684 1.2665095708058172 0.2053307050893809 1.0 0.6082731936784184 6 P04062 1 +Pain 0.2980997208379652 1.2664710498292049 0.2053444877694206 1.0 0.6082731936784184 185 P14174,P50402,Q8NBM4,Q8TAA9,Q9BRK0,P40939,Q14739,Q13423,Q14566,Q15800,O60313,O75844,Q9NR77,O15269,P12235,Q14108,Q70HW3,Q12769,P51798,Q15043,P23786,Q9NZJ7,O15460,Q15165,P42892,P00846,Q9UGP8,P21912,P04062,P21964,P07602,P51530,P35637,Q9Y4P3,Q13510,Q9H6K4,Q92804,Q01844 38 +Mildly elevated creatine kinase 0.4316295611676564 1.266410468218337 0.2053661650329012 1.0 0.6082731936784184 25 P39210,Q9BPX6,Q969X5,O75340,O75648,P40939,Q16836 7 +Demyelinating peripheral neuropathy 0.4532567207074905 1.2649615489702166 0.2058851118340028 1.0 0.6090158698666243 19 P41440,P00846,P07196,Q9NR77,P03915,P03886 6 +Bile duct proliferation 0.6905470734151383 1.2628642793444755 0.206637959142063 1.0 0.609258144932991 5 Q9NSD9,Q5XKP0 2 +Abnormal enchondral ossification 0.4222824272409669 1.2612890006122095 0.2072047426975718 1.0 0.609258144932991 27 P40855,Q7RTS9,O75381,Q9UBM7,P38435,Q9UG56,P56589,O95202,P08236,Q14739 10 +Hypergranulosis 0.8138082005948126 1.261033734884706 0.2072966931363014 1.0 0.609258144932991 3 P16615 1 +Generalized lipodystrophy 0.7202866961026567 1.2581615290481505 0.2083333449092441 1.0 0.6106756887583981 4 O75844 1 +Hand polydactyly 0.3970672004057696 1.258045550058387 0.2083752834588188 1.0 0.6106756887583981 32 Q7Z4L5,O75845,Q10713,Q9UHX1,Q15067,P21964,O95202,Q9UM00,Q96J42,Q14739,Q5H8A4 11 +Abnormality of the abdominal organs 0.2839167433646721 1.2554792805662678 0.2093048249886886 1.0 0.6112394570415368 356 P14174,O75431,O96000,Q15904,O43676,P03886,Q86Y39,Q7Z2Z2,Q8WWI5,Q8N511,Q5XKP0,P09601,P55263,P56589,P36551,Q9Y276,Q9NZ08,P20674,Q9NSD9,Q86SQ9,Q8NCH0,Q9UHX1,Q9NZJ7,P00846,P21912,P04062,Q10713,P21964,P07602,Q13510,Q96J42,Q9H3H5,Q7KZN9,Q9Y6M9,Q9HC21,Q14739,Q5H8A4,Q96AA3,P40855,P39210,P00403,Q96A33,Q14108,Q7Z4L5,O75845,Q9BT22,P03915,P10619,Q8NBM4,Q15392,Q15067,P40939,P12235,O15118,O75340,Q16836,O43681,P23786,Q9NVI7,Q9NQH7,O75381,Q9H0U3,Q9NX14,O75880,Q96CU9,Q9BUB7,O95202,O75648,Q9NPL8,P35610,Q9Y375,Q12769,P51798,Q658P3,P22830,P23458,P11802,P31751,Q9NWS8,Q9UBM7,Q9UGP8,O75306,P08236,Q9Y4P3,P50416,Q01844 86 +Abnormal conjunctiva morphology 0.4251598173169491 1.248004426512439 0.2120294361575023 1.0 0.6130201061200121 26 P21912,Q8NBM4,P10619,Q13510,Q14739 5 +Fetal ultrasound soft marker 0.4535916647441713 1.2473833105245469 0.2122569830873182 1.0 0.6130201061200121 18 P40855,O96011,O75381,P56589,P61978,P50542,P16435 7 +Ureteral duplication 0.5550235925265677 1.244689220597189 0.2132460098226514 1.0 0.613418913301423 9 Q96J42,O75844,P23786 3 +Infantile muscular hypotonia 0.3539248839459619 1.2428492408350238 0.2139233933526896 1.0 0.6137739438584996 66 Q7Z2Z2,Q9H3H5,Q9H936,P00846,Q9Y487,O75306,O43819,P03915,P07602,O95169,Q15043,Q2TAA5,Q9NZJ7,Q13510,P17900,P03886 16 +Abnormality of the amniotic fluid 0.3313403376249644 1.2411243893488275 0.2145598010051368 1.0 0.614813753313951 90 Q9BV10,Q9BUB7,P40939,Q14739,Q7LGA3,O75844,Q9UM00,Q70HW3,P51798,Q9BT22,Q9UHX1,P23786,Q9NVI7,Q6NUK1,P04062,P21964,Q969X5,Q96J42,P16435 19 +Abnormal meningeal morphology 0.4360437044456293 1.2400553891257142 0.2149549078241095 1.0 0.6151926218926108 23 O75845,Q10713,Q9UHX1,P21964,Q8TAA9,Q9NQH7 6 +Schistocytosis 0.7151199527964658 1.236044431914004 0.2164420483009865 1.0 0.6181829134551367 4 O75845 1 +Mandibular aplasia 0.8075607449464821 1.2357825315498523 0.2165394098855291 1.0 0.6181829134551367 3 P53701 1 +Fatigue 0.3392663336801386 1.2325512943751828 0.2177432180237353 1.0 0.6199240166889959 82 P21912,P04062,Q8NBM4,Q658P3,Q13423,O60313,Q53H12,Q4J6C6,P12235,P07602,O15460,P35637,Q9NZJ7,Q70HW3,Q92804,P50416,Q14739,Q15165 18 +Abdominal distention 0.4389698440383119 1.232498222439514 0.2177630302310234 1.0 0.6199240166889959 22 Q7RTS9,Q9UGP8,P04062,O43681,P07602,O75648,Q9NZJ7 7 +Intestinal pseudo obstruction 0.5313673792310523 1.229865859177966 0.2187473408212308 1.0 0.6199240166889959 11 P03886,P00403 2 +Poikiloderma 0.71357105263093 1.2294139582808483 0.2189166394857351 1.0 0.6199240166889959 4 O75431 1 +Abnormal circulating proteinogenic amino acid derivative concentration 0.4268879544545643 1.2277966161257143 0.2195233262767937 1.0 0.6199240166889959 25 Q5XKP0,P00846,O95298,O96000,Q9P0J0,P03915,P03886,O75880 8 +Amelogenesis imperfecta 0.7384230287859779 1.2269292687917053 0.2198491766439203 1.0 0.6199240166889959 2 Q13586 1 +Abnormality of skin pigmentation 0.3124241329959281 1.2267744605337183 0.2199073724449483 1.0 0.6199240166889959 132 Q7LGA3,P21912,P04062,P53701,Q14739,P00403,O75844,P21964,P07602,P51648,Q9NZJ7,P03886,Q06136,P16615 14 +Basal ganglia gliosis 0.5412619110519208 1.2257367976414788 0.2202977379451964 1.0 0.6199240166889959 10 P00846,O75306,O43819 3 +Limb girdle muscle weakness 0.4222018034851303 1.223466332909048 0.2211536127208391 1.0 0.619970214190697 26 Q9H3H5,O14979,O60313,P12235,O75340,P07602,P51530,Q9NZJ7 8 +Muscle fiber atrophy 0.4445686312593909 1.2229199158671318 0.2213599455294588 1.0 0.619970214190697 20 Q13586,P50402,Q9BTV4,Q99720,Q96RL7,P35637,P23786,P61978,P54098,P22626 10 +Abnormality of the alveolar ridges 0.6432606064166182 1.2216872604308386 0.2218259157186728 1.0 0.620046079452236 6 P17302,Q9UBM7,Q15392 3 +Anophthalmia 0.5036613753245605 1.2136873151532137 0.224867150073045 1.0 0.6239598358415829 13 O43505,P52732,P53701,Q9NX14,Q96J42,Q9H5K3 6 +Severe muscular hypotonia 0.4071279789567971 1.213329438163528 0.2250038921748105 1.0 0.6239598358415829 29 O43505,P40855,O96011,Q9NWS8,O75746,O75381,Q12756,Q9NWM8,P53007,P56589,O95831,Q08209,Q5H8A4,Q01105 14 +Inappropriate behavior 0.448248476117337 1.209626767591058 0.2264221420841137 1.0 0.624952224734427 17 P07602,Q9NZJ7 2 +Malabsorption 0.3557295275397207 1.208051793962157 0.2270273404605511 1.0 0.625601257457294 55 Q9UJW0,P14174,Q8NBM4,Q08J23,Q14739,Q14566,P40855,Q7Z2Z2,P09601,Q96A33,P56589,P42345,Q9NZ08,P50542,Q15056,P18074,Q9Y6B6,O96011,O75381,Q9Y4P3,P54098,O76024 22 +Limited wrist movement 0.6387607189325608 1.2006092893364395 0.2299027959578388 1.0 0.628310407311901 6 O75844 1 +Abnormal pelvis bone morphology 0.7987480438184549 1.2001909029624165 0.230065207549192 1.0 0.628310407311901 3 Q7RTS9,P16435 2 +Nonimmune hydrops fetalis 0.41932184940278 1.1995411319434808 0.2303176010668275 1.0 0.628310407311901 26 P04062,Q9BT22,O96000,Q14739 4 +Prenatal movement abnormality 0.352081644854203 1.1994028473938576 0.2303713409611509 1.0 0.628310407311901 63 P40855,Q16637,Q9H3H5,Q9UBM7,P04062,Q7KZN9,O75844,Q4J6C6,Q969X5,P56589,O95202,P51530,Q9HC21,Q9UM00,Q70HW3,Q5H8A4 16 +Stillbirth 0.5364658246183721 1.1986889501775075 0.2306489162257627 1.0 0.6285695646501094 10 P04062,Q14739,O75844 3 +Nyctalopia 0.3740162176173314 1.1976541985627671 0.2310516669406681 1.0 0.6285695646501094 37 P40855,Q9H3H5,Q86SQ9,O75381,P38435,Q10713,Q96S66,Q13432,P56589,Q96HR9,Q8TC12,P40939,Q9Y287 13 +Short ribs 0.5562762098689751 1.1974365818313109 0.2311364322668936 1.0 0.6285695646501094 8 Q7Z4L5,Q14739 2 +Lower limb hyperreflexia 0.4466152082327156 1.196797397808205 0.2313855327869654 1.0 0.628830670954849 18 Q14739,P13073,P21912 3 +Chordee 0.5964206762522265 1.1961544119116143 0.2316363072921363 1.0 0.6288451756437579 7 Q9NX14,P53701 2 +Abnormal circulating bilirubin concentration 0.4097679644684779 1.1941787575984748 0.2324080506483636 1.0 0.6292714439046083 28 P41440,P40855,Q9NSD9,P28288,O75845,Q9UGP8,Q9UJS0,P55263,P36551,P23786,O75648,Q14739 12 +Abnormality of prenatal development or birth 0.2980450571484033 1.193432080479607 0.2327001972750833 1.0 0.6294169444595228 246 Q96CU9,Q9H3H5,Q16637,Q7KZN9,O96000,Q9Y487,Q10469,Q9BV10,Q9Y6M9,Q9BUB7,Q8TAA9,O95202,Q9HC21,O43676,P40939,P03886,Q86Y39,Q14739,Q5H8A4,Q7LGA3,P40855,Q9NPL8,Q9NXE4,O60313,O75844,P29084,Q4J6C6,O15118,P56589,P17302,Q9UM00,Q70HW3,O75718,Q9NSD9,Q9Y375,P51798,Q9BT22,Q9UHX1,P23786,Q9NVI7,Q6NUK1,O75381,Q9UBM7,P04062,P10619,P50416,O75306,P21964,Q969X5,P51530,P08236,Q9Y4P3,Q13510,Q9NX14,Q96J42,P16435 56 +Decreased cd4 cd8 ratio 0.7050563186553525 1.1929672711254908 0.2328821911893408 1.0 0.6295375811383833 4 Q13432 1 +Deposits immunoreactive to beta amyloid protein 0.7302878598248035 1.1903907119830104 0.2338928619169711 1.0 0.630781102591855 2 O96008 1 +Decreased circulating aldosterone level 0.7299749687109143 1.188986760035111 0.2344448770142422 1.0 0.6312224239136283 2 Q13423 1 +Butterfly vertebrae 0.7037419680386201 1.1873422037557737 0.2350926673988926 1.0 0.6317856903353233 4 O75845 1 +Meningitis 0.5540898267928344 1.1857387276053903 0.2357254954210343 1.0 0.6323736651166156 8 Q8TAA9,O15460,Q8NBM4 3 +Severe short stature 0.4253023794994024 1.1836046413614187 0.2365696022567476 1.0 0.6331553256661318 24 Q7RTS9,P21912,P10619,P53701,Q15392 5 +Abnormality of the umbilical cord 0.6345362025415162 1.180814244443396 0.2376765240935987 1.0 0.6346351010471267 6 O75844 1 +Genetic anticipation 0.7277847309136534 1.179162222453835 0.2383335857380804 1.0 0.6349095871232672 2 Q9UBB4 1 +Low back pain 0.7277847309136369 1.1791622224537608 0.2383335857381099 1.0 0.6349095871232672 2 Q8WVX9 1 +Severe lactic acidosis 0.7930265973684245 1.1771064675538383 0.2391530140001088 1.0 0.6360852824420473 3 Q70HW3 1 +Decreased circulating progesterone 0.6712022042884924 1.1766625751484168 0.2393302110279549 1.0 0.6360852824420473 5 P16435,P49770,Q13144 3 +Abnormal circulating progesterone level 0.6712022042884924 1.1766625751484168 0.2393302110279549 1.0 0.6360852824420473 5 P16435,P49770,Q13144 3 +Progressive 0.3102068335511914 1.1759124439207282 0.2396298656840663 1.0 0.6365124896025459 112 Q16637,Q13126,Q99720,Q9Y6M9,O95470,O75298,Q8NBU5,Q5XKP0,P39210,P55263,O60313,P12235,Q9Y4W6,P15586,Q12769,O14653,P61619,Q15043,Q9H0B6,P04062,P27544,Q13510,Q9NR28 23 +Increased connective tissue 0.5520900588398685 1.175035098187058 0.2399806741888532 1.0 0.6370749994978712 8 O95831,P31751,P07196,O75431 4 +Abnormal anatomic location of the heart 0.5097935479273645 1.1745108792241918 0.2401904569090422 1.0 0.637153340014413 12 Q10713,O75844 2 +Abnormal muscle fiber protein expression 0.6331390820794753 1.174266503149359 0.240288295841315 1.0 0.637153340014413 6 Q9H5K3 1 +Decreased number of large peripheral myelinated nerve fibers 0.6327675222129902 1.172525068338723 0.2409863135801178 1.0 0.6382654848694218 6 P07196,Q8TB36,O15269 3 +Hypoplastic vertebral bodies 0.6321797461145574 1.1697702004448252 0.2420934588395804 1.0 0.639718701501129 6 Q14739 1 +Epispadias 0.7905067459432598 1.166946328214058 0.2432320450497913 1.0 0.6418700885609006 3 P53701 1 +Broad phalanx of the toes 0.6688232941606259 1.1660597396613683 0.2435902928784894 1.0 0.6418700885609006 5 Q7LGA3 1 +Morphological abnormality of the corticospinal tract 0.4699157044122821 1.1660158189223906 0.2436080497615464 1.0 0.6418700885609006 15 P35637,P00846,O75298 3 +Abnormality of the basal ganglia 0.3282046229117032 1.1639808948374806 0.2444317543164094 1.0 0.6433741840230928 88 Q96CU9,Q08J23,Q7KZN9,Q96RL7,Q9BPX6,Q9ULK4,Q96N66,P03886,Q96AA3,Q8WWI5,P00403,Q8N183,O60313,Q9P0J0,O75340,P17302,Q96DP5,Q9NZ01,O00483,P03915,Q8NI60,P23786,O95831,P00846,P04062,O75306,O43819,O95169,Q96DA6 29 +Macrogyria 0.5899753728134622 1.1639118821428107 0.2444597237852912 1.0 0.6433741840230928 7 Q15392,Q9H5K3 2 +Corneal dystrophy 0.6966183480384824 1.1568627505509024 0.2473284394716306 1.0 0.6486163289165621 4 P12235 1 +Vitritis 0.6964737594509325 1.1562442741393222 0.2475812549004858 1.0 0.6486163289165621 4 Q9NX14,P53701 2 +Premature birth 0.3593163876576953 1.1550467824891677 0.2480712692769395 1.0 0.6492217408820532 44 P40855,Q9NXE4,P51798,O75381,Q9UBM7,P04062,O75844,Q9BV10,Q9BUB7,O43676,Q9NX14 11 +Abnormal oral mucosa morphology 0.350074365645492 1.154980316214849 0.2480984871856122 1.0 0.6492217408820532 59 O75431,Q8NBM4,Q10469,Q15392,Q14739,Q13546,Q7Z2Z2,Q14108,Q9UM00,Q9NZ08,Q15056,O75845,Q9UBM7,P04062,P08236,Q9Y4P3,P53634,Q5JRA6,P49257 19 +Incomplete penetrance 0.3812638392564843 1.152348016169334 0.2491780932773617 1.0 0.6513029226451064 33 O14979,P00846,P21912,Q9UBB4,O60313,P03915,P36551,Q8NFG4,P03886,Q3ZAQ7 10 +Retrocollis 0.786228482003114 1.149706849385039 0.2502646323147379 1.0 0.6518665433149651 3 P35637,Q99720 2 +Oligohydramnios 0.3853673546524703 1.1488777304916806 0.2506064015762221 1.0 0.6518665433149651 32 Q9UHX1,Q969X5,P23786,Q96J42,Q6NUK1,P16435,Q7LGA3 7 +Ankylosis 0.6645989408955192 1.1472331007726626 0.2512852946285639 1.0 0.652019924178761 5 O75844 1 +Broad palm 0.6272023859689444 1.1464390546953642 0.2516135308880711 1.0 0.652019924178761 6 P51812,Q7RTS9,Q14739 3 +Abnormality of the liver 0.2907726197779213 1.145657425237389 0.251936926429505 1.0 0.652019924178761 305 P14174,O75431,O96000,Q15904,O43676,P03886,Q86Y39,Q7Z2Z2,Q8WWI5,Q8N511,Q5XKP0,P55263,P09601,P56589,P36551,Q9Y276,P20674,Q9NSD9,Q86SQ9,Q9NZJ7,P00846,P21912,P04062,Q10713,P21964,P07602,Q13510,Q96J42,Q9H3H5,Q7KZN9,Q9Y6M9,Q9HC21,Q14739,Q5H8A4,Q96AA3,P40855,P39210,Q96A33,Q14108,Q7Z4L5,O75845,Q9BT22,P03915,P10619,Q15067,P40939,P12235,O15118,O75340,Q16836,O43681,P23786,Q9NVI7,O75381,Q9H0U3,Q9NX14,O75880,Q96CU9,Q9BUB7,O95202,O75648,Q9NPL8,P35610,Q9Y375,P51798,Q658P3,P22830,P23458,P31751,Q9NWS8,Q9UBM7,Q9UGP8,O75306,P08236,Q9Y4P3,P50416,Q01844 77 +Osteopenia 0.3381812163502948 1.145025554583139 0.2521985717375539 1.0 0.652019924178761 76 O75431,Q13126,Q9Y487,O43292,Q10469,O15228,P61978,Q7Z2Z2,O75844,P29084,Q14108,O75718,Q9NSD9,Q15056,Q9Y5U9,Q9H490,Q9NWM8,Q9NZJ7,Q32P28,P04062,P07602,Q9Y4P3,Q5JRA6 23 +Fetal akinesia sequence 0.5861907161534077 1.1449690423993273 0.2522219815553477 1.0 0.652019924178761 7 P04062 1 +Pulmonary hypoplasia 0.4167244203858256 1.1447347904380227 0.2523190351149127 1.0 0.652019924178761 25 Q9H3H5,O96000,O75844,Q6NUK1,Q8TAA9,Q14739 6 +Abnormal systemic blood pressure 0.3197493289769872 1.1444411938097927 0.2524407126785513 1.0 0.652019924178761 94 P42892,P21912,P04062,P00403,Q10713,O75844,Q13423,P21964,P03915,P07602,O43681,Q9BUB7,Q8TAA9,Q9NZJ7,P03886,P16435,Q9NQH7 17 +Ascites 0.4126584724800281 1.1440633583633837 0.2525973621725741 1.0 0.6520569653378786 26 P04062,O15118,P08236,Q14108,Q13510,Q14739,Q01844 7 +Elevated circulating long chain fatty acid concentration 0.7839312466974722 1.1404560160981692 0.2540963670945828 1.0 0.6531005112994125 3 P40855 1 +Type ii transferrin isoform profile 0.692571277943062 1.1395545985594318 0.254471909417024 1.0 0.6531005112994125 4 Q10469 1 +Microretrognathia 0.4658785867979174 1.1390760629830354 0.2546714304175728 1.0 0.6531005112994125 15 Q8NCH0,Q8WVQ1,Q9BUB7,P53007,Q9UHX1,Q15738 6 +Generalized edema 0.6924365838366354 1.138978671722266 0.2547120501292121 1.0 0.6531005112994125 4 Q9NSD9,Q9H3H5 2 +Plantar hyperkeratosis 0.3842731905267705 1.138634356896746 0.2548556922508271 1.0 0.6531033455779027 32 P42167,P21912,P16615 3 +Progressive cerebellar ataxia 0.3638526595380603 1.1352499851777842 0.2562705914887551 1.0 0.6540781674657561 40 Q96CU9,P41440,O14773,Q9BUK6,Q9Y487,Q7KZN9,Q9UBB4,O75306,O15020,Q9P0J0,Q8NI60,P35637 12 +Duplication involving bones of the feet 0.4352269235768007 1.1320079364054694 0.2576310978146943 1.0 0.6557132316706906 19 Q7Z4L5,Q10713,P21964,Q96J42,Q14739 5 +Hyperthyroidism 0.5245564727482928 1.1313987673782184 0.2578872900780693 1.0 0.6557132316706906 10 P21964,P12235 2 +Abnormal circulating carbohydrate concentration 0.3633514550697618 1.1300555709596916 0.258452809218632 1.0 0.6557461722159479 40 Q96CU9,Q9NPL8,Q9Y375,P21912,O96000,Q9Y6M9,O43676,Q70HW3,Q9NX14,P03886,Q86Y39 11 +Progressive sensorineural hearing impairment 0.502277786723567 1.1293741385367164 0.2587400376746638 1.0 0.6557461722159479 12 P03915,P03886,P00403 3 +Prominent superficial blood vessels 0.5021705579746751 1.1287296219862324 0.2590119093245668 1.0 0.6557461722159479 12 Q9Y487,O75844 2 +Joint contracture of the 5th finger 0.716207759699625 1.127334280339823 0.2596011738546553 1.0 0.6557610956567611 2 P17302 1 +Retinal atrophy 0.4019228800062781 1.1263374518118 0.2600227109962474 1.0 0.6557610956567611 28 P04062,Q10713,Q8TC12,Q96HR9,P51648,O75648,Q7LGA3 7 +Abnormality of the supraorbital ridges 0.4216453705587636 1.126289045321883 0.2600431931052673 1.0 0.6557610956567611 23 P40855,O96011,P52732,O75381,Q08J23,P51812,P56589,Q6NUK1,P16435 9 +Opsoclonus 0.7803077169175514 1.1258735341007395 0.2602190531949748 1.0 0.655843620318688 3 P04062 1 +Absent brainstem auditory responses 0.7801371131840205 1.1251872521377069 0.2605096939215374 1.0 0.6562151828193977 3 O60313 1 +Neurogenic bladder 0.5233140655100412 1.124370164299805 0.2608560237856259 1.0 0.6567265390031526 10 Q8N5K1,Q8TAA9,P56589,P17302,Q96DP5,O76024 6 +Abnormal ossification involving the femoral head and neck 0.6887107428695793 1.1230511955447695 0.2614157519719766 1.0 0.657518346750161 4 Q14739 1 +Abnormal echocardiogram 0.658857107407509 1.1216490549682057 0.2620116854804952 1.0 0.6581406984291094 5 P54098,P49748,P12235 3 +Absence of subcutaneous fat 0.5807891262252917 1.1179237747568225 0.2635995500258019 1.0 0.6582555597179514 7 O75844 1 +Abnormal renal cortex morphology 0.34692089565139 1.1175686791090833 0.2637512519420635 1.0 0.6582555597179514 59 O75431,Q12769,P00846,P00403,Q8NBM4,P61619,P21912,P03915,Q14108,P03886,O95470,P23458,Q9NQH7 13 +Skeletal muscle hypertrophy 0.3574284666473096 1.1164604414149175 0.2642250940998718 1.0 0.6586938961728035 43 Q15056,P21912,Q96A33,O00170,Q10713,Q9NR77,Q8NCE2,Q96S52,P10253,O75648,P61978,Q9Y4P3,Q9H5K3,Q7LGA3 14 +Abnormality of hindbrain morphology 0.2924891167327664 1.1151964049224383 0.2647662663247507 1.0 0.6591139751753486 281 O43505,Q96CU9,Q9H3H5,Q9BUK6,Q99720,Q9Y487,O43292,Q9BV10,O15020,Q8TAA9,O95202,Q9HC21,O75648,Q8N2K0,Q5H8A4,P41440,O75503,Q8WWI5,Q9NXE4,Q5XKP0,Q9C0E8,P51572,Q8IV08,O60313,P46977,P29084,P12235,P17302,Q14108,Q9Y276,Q9UM00,Q8TCJ2,Q9Y4W6,Q9H5K3,Q8N0X7,Q86SQ9,Q9H936,Q9H490,O75845,Q96JX3,P51798,Q9BT22,Q9UBB4,P13073,Q8NI60,Q15043,P23786,Q92643,Q9NVI7,Q6NUK1,P00846,O14773,Q6DKK2,P21912,Q9UBM7,P51812,Q10713,P15291,Q9Y320,P35637,Q9Y4P3,Q9H6K4,Q96J42,P16435 64 +Thoracic hypoplasia 0.3959101235830187 1.1144232013568292 0.2650976744304443 1.0 0.6591139751753486 29 Q7Z4L5,P51798,P04062,Q96A33,Q9UHX1,Q9UM00,Q14739,P16435,O75718 9 +Hepatic cysts 0.6571060812057599 1.113848844866569 0.2653440382484542 1.0 0.6591139751753486 5 Q7Z4L5,P23458 2 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Q96CU9,O95298,Q7KZN9,O96000,Q9Y6N5,Q9Y6M9,Q9BUB7,O14949,Q9HC21,O43676,O75648,P40939,P03886,Q86Y39,Q9NPL8,Q5XKP0,P39210,P00403,P35610,Q6P4A7,Q9P0J0,P12235,Q86VD7,Q70HW3,O14678,Q16836,Q9UBX3,Q9Y375,Q96JX3,P13073,P03915,Q8NI60,P23786,Q9NVI7,Q9NWS8,P00846,P21912,Q53H12,Q10713,O75306,O43819,Q9NX14,O75880 43 +Fractures of the long bones 0.6837503465402344 1.1018582045967322 0.270523321410743 1.0 0.6614552400358585 4 P51798 1 +Adult onset 0.3398774737556724 1.101843517736833 0.2705297075135746 1.0 0.6614552400358585 70 Q16637,O14979,Q13586,Q14566,P41440,Q8IV08,P12235,O15118,P36551,P38435,Q9NZJ7,P31751,Q9UGP8,P21912,P04062,Q9Y6M1,Q9H0U3,Q9NQZ5,P07602,Q9NWW5 20 +Foot acroosteolysis 0.6835800954735827 1.101131092435779 0.2708396065564376 1.0 0.6615069708110858 4 O75431,O75844 2 +Osteolysis involving bones of the feet 0.6835800954735827 1.101131092435779 0.2708396065564376 1.0 0.6615069708110858 4 O75431,O75844 2 +Low frustration tolerance 0.5281347204368965 1.096892554306418 0.2726883639568291 1.0 0.6638151309243706 9 Q9UHX1 1 +Abnormal joint morphology 0.292020188637813 1.094591506637122 0.2736956382071422 1.0 0.6649381835976277 276 P49902,P14174,Q9H3H5,O75431,P50402,Q8NBM4,Q9Y487,Q15392,Q9BV10,Q9BUB7,Q8TAA9,O95202,P51571,Q14739,O75298,Q15041,Q7LGA3,Q8NBU5,Q7RTS9,Q96A33,O75844,Q9NR77,O15269,P29084,O75340,Q14108,Q8N0X7,P51798,P38435,P61619,Q8NCH0,Q86XL3,Q9UHX1,Q96PU5,Q15043,P23786,Q9NZJ7,P37268,O15460,P42892,Q9UBM7,P21912,P04062,P21964,Q969X5,P07602,P08236,Q9NX62,Q9Y4P3,Q13510,Q9H6K4,P49257,P16435 53 +Hypotension 0.4065653682764671 1.0932002372010257 0.2743058929288906 1.0 0.6650103711112046 26 P04062,O43681,P07602,Q9NZJ7,Q13423 5 +Progressive spastic paraplegia 0.3883860115537804 1.090530944248553 0.2754793299834861 1.0 0.6659159543174236 30 Q7KZN9,Q9H0B6,P00846,O75298 4 +Abnormality of the septum pellucidum 0.3564557406608301 1.089080290608243 0.2761184805418282 1.0 0.6659159543174236 42 Q9NX14,P53701,Q15392,Q9BV10,O95202,Q96N66,Q9NZ01,Q9H5K3 8 +Radioulnar dislocation 0.771073587642733 1.0887695210741288 0.2762555354331857 1.0 0.6659159543174236 3 P16435 1 +Abnormality of the radioulnar joints 0.771073587642733 1.0887695210741288 0.2762555354331857 1.0 0.6659159543174236 3 P16435 1 +Recurrent fever 0.4449382327252416 1.0874248715671928 0.2768490843166193 1.0 0.6659159543174236 16 Q13586,P51572,Q9NR77,Q13510,P61978 5 +Skin rash 0.4291783660462815 1.0872063816935384 0.2769456111156922 1.0 0.6659159543174236 19 Q7Z2Z2,P14174,P21912,P17302,Q14739,Q06136 6 +Cns hypomyelination 0.3601133559986212 1.0824308889729026 0.2790611090945436 1.0 0.6659159543174236 39 Q9H3H5,Q9NWS8,Q9NXE4,Q99720,P51572,P49770,O75340,Q8TB36,P35637,Q5T8D3,Q13144 11 +Abnormality of the musculature of the thigh 0.5729984402155494 1.07890572140291 0.2806297580548706 1.0 0.6680135148011025 7 P07196,O14979,P50402 3 +Steroid resistant nephrotic syndrome 0.6492495208529718 1.0788663330388388 0.2806473190729206 1.0 0.6680135148011025 5 Q8N1F7,Q12769 2 +Hypoproteinemia 0.7680751173708704 1.076741224357753 0.2815958898524444 1.0 0.6692587354720663 3 Q9H3H5,P49748 2 +Confusion 0.4432668928339126 1.0758052350158025 0.2820143705267046 1.0 0.6692587354720663 16 O96008,Q8NBM4,P36551,P40939,Q16836 5 +Equinovarus deformity 0.612025191436281 1.0752952195111154 0.2822425758193052 1.0 0.6692587354720663 6 Q969X5,P40939 2 +Glomerulopathy 0.5047051204870648 1.074883327569594 0.2824269673189159 1.0 0.6692587354720663 11 Q14108,Q8NBM4 2 +Proximal muscle weakness in lower limbs 0.426730833384768 1.069055011553674 0.2850448818459536 1.0 0.6718496134867077 19 Q16637,P50402,Q9BTV4,P07196,P12235,Q8NCE2,P36551,Q3ZAQ7 8 +Arthrogryposis multiplex congenita 0.3611400196625816 1.0678369647906 0.2855940606517757 1.0 0.6724360970720813 37 Q96AA3,P04062,Q8NCH0,O75844,Q969X5 5 +Ridged nail 0.6103287669560874 1.0673458488358292 0.2858156915113428 1.0 0.6724360970720813 6 P16615 1 +Generalized hyperpigmentation 0.4916788846853336 1.065608057985467 0.2866008550910641 1.0 0.6730933459903926 12 P51648 1 +Increased intramyocellular lipid droplets 0.6097210490266984 1.064498359010192 0.2871029973931756 1.0 0.6739272203153333 6 Q8NI60,Q9Y4W6,Q9BUK6 3 +Chronic hepatic failure 0.6746545670634545 1.0630420610629403 0.2877628773738543 1.0 0.6745907050875278 4 Q10713 1 +Decreased plasma carnitine 0.4912291282570957 1.0628999393844505 0.2878273305207588 1.0 0.6745907050875278 12 P40939,Q16836,P23786,O75880 4 +Abnormal circulating acetylcarnitine concentration 0.569619736572486 1.0619835103856323 0.2882431711303552 1.0 0.6749367845772605 7 P40939,Q16836 2 +Bone fracture 0.5309915111888825 1.0619253061271023 0.2882695956826056 1.0 0.6749367845772605 8 P51798,Q13126 2 +Infantile spasms 0.3756211224040309 1.0574613426536852 0.2903010883380998 1.0 0.678306775504933 32 Q9UBX3,P00846,P03915,O75340,Q13510,P03886 6 +Premature rupture of membranes 0.6080308929283935 1.056579827090883 0.290703391142288 1.0 0.6785547316423657 6 O75844 1 +Decreased adipose tissue 0.4530886477329982 1.0535452133593692 0.2920911836698108 1.0 0.6796271748275224 15 Q6NUK1,O75431,P29084,O75844 4 +Decreased specific antibody response to protein vaccine 0.7620857759919333 1.052748212106625 0.2924564058574315 1.0 0.6796271748275224 3 Q9BV10 1 +Abnormality of muscle size 0.2894335221673874 1.04988082293962 0.2937729095356347 1.0 0.6806210821837677 203 O43505,Q16637,O14979,Q13586,Q13126,P50402,Q9BUK6,Q99720,Q9BTV4,P07196,Q9Y487,Q96GM8,Q96RL7,P10253,Q9HC21,P61978,O75648,Q8N2K0,O75298,Q7LGA3,P46020,Q9NPL8,P39210,P55263,P13473,Q96A33,O60313,Q9NR77,O15269,Q6P4A7,P12235,Q96B26,Q8TB36,P22626,Q9Y4W6,Q9H5K3,Q8N0X7,Q15056,Q9BQT8,Q9NWM8,O00170,O95831,Q9NVI7,Q15165,Q3ZAQ7,Q9H0B6,Q6DKK2,P21912,P51812,Q10713,P50416,Q8NCE2,Q969X5,Q96S52,Q96BR5,Q96DA6,P51530,O43819,Q13510,Q92804,P35637,Q9Y4P3,P51970,P54098 64 +Asymmetric septal hypertrophy 0.6986858573216564 1.0493001595880576 0.2940399925989827 1.0 0.6806210821837677 2 P15586 1 +Cachexia 0.4262957537651631 1.0487245841117472 0.2943048960805823 1.0 0.6806210821837677 18 P04062,P07602,Q9NZJ7 3 +Dysesthesia 0.6061525054403311 1.047780888121448 0.2947395698618962 1.0 0.6806210821837677 6 Q8NCH0 1 +Lissencephaly 0.3421683059114723 1.0475760646617214 0.2948339699483175 1.0 0.6806210821837677 49 O43505,Q9H936,Q9NWS8,Q16134,Q9Y487,Q86XL3,Q15392,Q9BV10,Q9Y320,Q9HC21,P23786,Q00535,Q9H5K3 13 +Intellectual disability progressive 0.4885769422678255 1.0469274922964256 0.2951330209375957 1.0 0.6806210821837677 12 Q9NX14,P53701,Q15067 3 +Motor deterioration 0.6049394146122806 1.0420993189142125 0.2973656343272244 1.0 0.6840006709273806 6 Q9NWW5,P21912 2 +Headache 0.3336691069100697 1.0415482162625165 0.297621187719516 1.0 0.6840944537355569 72 Q12769,P00846,P00403,Q9Y6N5,Q8NBM4,P21912,O60313,P04062,P12235,P03915,Q8TAA9,Q9NQZ5,P23786,P03886 14 +Endocarditis 0.6047831557243074 1.0413675289087705 0.2977050067107596 1.0 0.6840944537355569 6 P04062,Q8NBM4 2 +Abnormal cranial nerve physiology 0.3302611468720355 1.0407033782711708 0.2980132348524902 1.0 0.6844594697213585 76 Q9H3H5,Q8NBM4,P07196,P40855,Q9NR77,P12235,O75340,P56589,P17302,P51798,Q9UHX1,Q15043,Q9NZJ7,O75381,P21912,P51812,O43819,P07602,P51530,Q13510 20 +Thoracolumbar kyphoscoliosis 0.6964956195244311 1.0395879536245969 0.298531375957543 1.0 0.6849109041920552 2 Q10469 1 +Respiratory arrest 0.5267782413060567 1.0393150774355293 0.2986582249183165 1.0 0.6849109041920552 8 P13473,P23786,P49748 3 +Hypoglycemic coma 0.5172365687853043 1.0368324391261925 0.2998139546335765 1.0 0.6866863927432324 9 P31751,P00367,P40939,Q13423,Q16836 5 +Recurrent pharyngitis 0.7579891702754058 1.0363649871222014 0.3000318983570387 1.0 0.6866863927432324 3 Q9BV10 1 +Plagiocephaly 0.3732427613757484 1.035099947525977 0.3006222370820239 1.0 0.6873508434679809 32 Q969X5,Q96A33,Q10713,Q01105 4 +Cystic hygroma 0.5258308303989736 1.034230627107941 0.3010283593629905 1.0 0.6875931917254351 8 Q99567,P22681,Q96S52,P61978,Q14739 5 +Cholecystitis 0.5257088181481752 1.0335758249968354 0.3013345058728331 1.0 0.6878619046127584 8 P07602,Q9NZJ7 2 +Lower limb hypertonia 0.507239956127584 1.033336937285766 0.3014462471546091 1.0 0.6878619046127584 10 P21912 1 +Optic nerve hypoplasia 0.4237555187983267 1.032701047766339 0.3017438230686509 1.0 0.6880050016672106 17 P37268,Q9H5K3,Q9UHX1 3 +Short nail 0.6377879820403735 1.0278991383646905 0.3039972749191961 1.0 0.6905828246181508 5 O75844 1 +Hydranencephaly 0.6936795994993677 1.0271164521631917 0.3043656325781121 1.0 0.6905828246181508 2 O43175 1 +Paralysis 0.3402056170892186 1.0250537973544942 0.3053378043309032 1.0 0.6908668969954612 53 P50402,P51798,Q9BTV4,P21912,P04062,Q9NR77,Q8TB36,P36551,P10253,Q9HC21,P35637,P17900,Q92804,Q15165 14 +Premature loss of teeth 0.4732744203167546 1.024758490362481 0.3054771569866443 1.0 0.6908668969954612 13 P17302,O75844,P51798,Q5JRA6 4 +Hemiparesis 0.4356177092505195 1.022575334688682 0.3065086766021716 1.0 0.692334868303554 16 P00403,Q8NBM4,O60313,P03915,P03886 5 +Iris coloboma 0.3566538020794785 1.0224255370754354 0.3065795390196226 1.0 0.692334868303554 37 Q9UBM7,P53701,Q10713,Q9UHX1,O75340,O95202,Q9NX14,Q5H8A4,Q9H5K3 9 +Skin nodule 0.4116947890283158 1.020274444508874 0.3075983198391259 1.0 0.6926375920174864 22 P11802,P21912,Q8NBM4,P35637,Q13510,P16615 6 +Retinal detachment 0.4723960821097505 1.0192831554161703 0.3080685585487184 1.0 0.6926375920174864 13 O43505,Q8NCH0,Q9BV10,P04439,Q9H5K3 5 +Failure to thrive 0.2845063799039404 1.0172344889031013 0.3090418927695377 1.0 0.6926375920174864 310 Q96CU9,Q9H3H5,Q7KZN9,O96000,Q9Y487,Q15392,Q9BV10,Q10469,Q9Y6M9,Q15067,Q9BUB7,Q15904,O95202,P51571,O43676,O15228,P40939,P03886,Q86Y39,Q14739,Q5H8A4,Q13423,O75352,Q96AA3,P40855,Q15800,Q7RTS9,Q5XKP0,P39210,Q9NPL8,P00403,Q7Z2Z2,P51572,P55263,O75844,P46977,P12235,Q9P0J0,Q4J6C6,Q3ZCQ8,P56589,P17302,Q9Y276,Q8TCJ2,Q16836,P20674,Q9NSD9,Q9H936,Q9BQT8,Q9Y375,Q96JX3,O75845,P13073,P03915,Q2TAA5,Q9NZJ7,P37268,Q6NUK1,P23458,P42892,P00846,O75381,Q9UBM7,P21912,P04062,P53701,O75306,P21964,O43819,P07602,Q9Y4P3,Q13510,Q9NX14,Q8N5M9,O75880 75 +Submucous cleft of soft and hard palate 0.4112780233017454 1.017017978279499 0.3091448769486817 1.0 0.6926375920174864 22 O75844,Q9H5K3,Q7LGA3 3 +Postural instability 0.4215754707536167 1.0168987157583134 0.3092016143501586 1.0 0.6926375920174864 17 P41440,O75503,P04062 3 +Abnormal blood transition element cation concentration 0.4834058737794152 1.0157742745030671 0.3097368891409493 1.0 0.6926375920174864 12 Q658P3,Q9Y487,Q15904,O43819,Q9Y276 5 +Status epilepticus with prominent motor symptoms 0.6630692433105752 1.013712929799277 0.3107197525734655 1.0 0.6938498556194499 4 P54098,Q13510 2 +Urinary incontinence 0.3444169531381537 1.0121253528081506 0.3114781217327509 1.0 0.6951742590255552 45 Q8WWI5,Q99720,Q9UBB4,P07196,P51812,Q8TAA9,O43681,P07602,P35637,Q9NZJ7,O75298 11 +Zonular cataract 0.5032934018072384 1.0109702100795257 0.312030688008035 1.0 0.6959761046393534 10 Q9H6K4,Q8WWV3 2 +Enlarged ovaries 0.7515690865118809 1.0107393840165155 0.3121411818057336 1.0 0.6959761046393534 3 P21912 1 +Epidermal hyperkeratosis 0.7511371816617715 1.0090177655439203 0.3129661141546975 1.0 0.6960371546490539 3 O75844 1 +Specific learning disability 0.3343560374400431 1.00811578911958 0.3133988785933566 1.0 0.6960371546490539 67 O43505,Q9NSD9,Q8N0X7,O75845,P00403,P53701,Q10713,Q9BPX6,P21964,P00367,P03915,P35637,Q9H6K4,Q9NX14,P03886,Q9H5K3 16 +Abnormality of the gingiva 0.3422903311826463 1.007929953845672 0.3134880904765016 1.0 0.6960371546490539 46 Q15056,Q9Y5U9,Q9UBM7,O75845,Q5JRA6,P04062,Q10469,Q15392,P49257,P08236,Q14108,Q9UM00,Q9Y4P3,P53634,Q14739 15 +Reduced consciousness confusion 0.2999192096183455 1.0075842604800611 0.3136540881228251 1.0 0.6960371546490539 129 Q96CU9,Q8NBM4,Q9Y6N5,O96000,Q9Y6M9,Q9HC21,O43676,P40939,Q13423,P03886,Q86Y39,Q5H8A4,Q96IX5,Q13144,Q9NPL8,P00403,P35610,P12235,P36551,Q9NZ08,O14678,P20674,Q16836,Q9Y375,P03915,O43681,P00367,P23786,Q9NZJ7,P31751,Q9NWS8,Q9UBM7,O96008,P04062,O75306,O43819,P07602,Q9NX14,P50416 39 +Hyperkinetic movements 0.4815268269960441 1.0044513980493217 0.3151610864613587 1.0 0.6979546148699594 12 Q9NZJ7 1 +Monochromacy 0.6883604505631974 1.0036099218862946 0.3155666702777155 1.0 0.6985152092813975 2 Q6P4Q7 1 +Short femur 0.5965543066994552 1.0028519126995552 0.315932317142048 1.0 0.6989033997901275 6 Q9UHX1 1 +Abnormal pupillary function 0.5110294709116739 1.0026140648018966 0.3160471070198918 1.0 0.6989033997901275 9 P07602,Q9NZJ7 2 +Abnormality of the intrahepatic bile duct 0.6602569649641369 1.0017617171821418 0.3164586908884217 1.0 0.699161177117273 4 Q10713,Q9Y5L0 2 +Enlarged thorax 0.4151705433803455 1.0017194573359276 0.3164791065824137 1.0 0.699161177117273 20 Q7RTS9,Q14739,O75844 3 +Prenatal maternal abnormality 0.4570725648834279 0.9978462443430816 0.3183539219162803 1.0 0.7009599568574706 14 P40939,Q8TAA9,P50416,Q14739,P16435 5 +Lipoma 0.6300794432447293 0.9936846808815938 0.3203764030642304 1.0 0.7040320136123197 5 Q8TAA9,P21912 2 +Abnormal systemic arterial morphology 0.2967006723787399 0.993079807761775 0.3206710633803822 1.0 0.7040320136123197 143 P00846,O75845,P38435,P21912,P04062,P53701,Q9NWM8,O75844,Q9UHX1,P21964,P07602,P03915,Q96PU5,Q9NZJ7,Q13510,P17900,P03886,Q7LGA3 18 +Abnormality of temperature regulation 0.2986311124053639 0.9917479602989692 0.3213204890030237 1.0 0.7046412659015743 110 Q8NBM4,Q9HC21,Q14739,P03886,Q13144,Q5XKP0,P00403,P51572,P35610,Q9NR77,Q12769,P51798,P03915,P23786,Q9NZJ7,Q2TAA5,P00846,P07602,Q13510 19 +Calvarial skull defect 0.5178707157131271 0.9915143866187662 0.321434470944697 1.0 0.7046412659015743 8 Q14739,Q5H8A4 2 +Abnormal peripheral nervous system physiology 0.3369639890083545 0.9871629379382848 0.3235627675754939 1.0 0.7068868608229928 51 P39210,Q99720,Q9UBB4,O60313,Q9NR77,O15269,Q9NQZ5,O43681,P07602,Q8TB36,Q9NZJ7,Q8N2K0 12 +Tongue fasciculations 0.4671921100457944 0.986836626738286 0.3237227359104815 1.0 0.7068868608229928 13 Q9BQT8,Q13510,Q16637 3 +Congenital contracture 0.3450907000816084 0.9843107981291932 0.3249627218486073 1.0 0.7076897298052846 43 Q96AA3,P04062,Q8NCH0,Q96A33,O75844,Q969X5 6 +Inappropriate crying 0.5537718341676897 0.9826516521018448 0.3257789135790512 1.0 0.7081209592121502 7 Q9NZJ7 1 +Prominent sternum 0.7442580221224394 0.9816391900239808 0.3262776332599129 1.0 0.7088687129430634 3 Q7RTS9 1 +Abnormality of the upper respiratory tract 0.3036561394431926 0.9797551677994852 0.327206986975268 1.0 0.7092791321857297 98 Q10469,Q9BV10,Q14739,Q7Z2Z2,Q7RTS9,P17302,Q9UHX1,Q03519,Q9NZJ7,O15460,Q15165,Q9UBM7,Q9H0U3,Q13432,P21964,P07602,P08236,P35637,Q13510,Q92804,P16435 21 +Abnormal renal physiology 0.2881976069415445 0.9781467607040056 0.3280017434401066 1.0 0.7092791321857297 164 Q96CU9,Q8NBM4,O96000,Q9Y6M9,Q8TAA9,O43676,P03886,Q86Y39,O95470,P40855,Q9NPL8,P00403,P09601,Q14108,Q7Z4L5,Q9Y375,Q12769,P61619,Q8NCH0,Q9BT22,P03915,P23786,O15460,P23458,Q9NQH7,P11802,Q9NWS8,P21912,P04062,Q10713,P05023,O75306,O43819,Q9Y4P3,Q9NX14,P49257 36 +Abnormality of the pharynx 0.3360366978320855 0.9779157853434824 0.32811597722603 1.0 0.7092791321857297 49 Q7RTS9,Q9H0U3,Q10469,Q9BV10,Q13432,Q03519,P21964,P08236,P17302,Q13510,O15460 11 +Patchy changes of bone mineral density 0.6262960654824797 0.9769160426177914 0.3286107188639025 1.0 0.7092791321857297 5 Q14739,Q13126 2 +Spinal muscular atrophy 0.4969220962583985 0.9748614477597808 0.3296289917025503 1.0 0.7092791321857297 10 Q13510,Q99720 2 +Proportionate tall stature 0.6814768460575659 0.973296409237004 0.3304060065668246 1.0 0.7092791321857297 2 O00170 1 +Deviated nasal septum 0.6814768460575651 0.9732964092370006 0.3304060065668264 1.0 0.7092791321857297 2 Q15233 1 +Limb dysmetria 0.6814768460575651 0.9732964092370006 0.3304060065668264 1.0 0.7092791321857297 2 P54098 1 +Metaphyseal cupping 0.7420970266040433 0.9730559281203864 0.3305255063179655 1.0 0.7092791321857297 3 O95831,Q14739 2 +Short middle phalanx of finger 0.6534329010341442 0.9728063448775892 0.330649558667111 1.0 0.7092791321857297 4 Q9UHX1 1 +Pharyngitis 0.6534023458606051 0.9726768477204704 0.3307139355410879 1.0 0.7092791321857297 4 Q9BV10 1 +Hypokinesia 0.4530312536101671 0.9717353619424997 0.3311822198140937 1.0 0.7092791321857297 14 P04062,P13473,P12235,Q2TAA5,O95831 5 +Mild short stature 0.6525927604424004 0.9692462321787256 0.3324223490487508 1.0 0.7104287329017612 4 Q14739 1 +Mottled pigmentation 0.7396627026598941 0.9633975682901936 0.3353480461735962 1.0 0.7155940122862592 3 O75844 1 +Atonic seizure 0.4009884736202403 0.9621048225182022 0.3359969519029078 1.0 0.7160642016833133 23 Q01105,Q13510,O14653 3 +Progressive microcephaly 0.3457770723960265 0.9609248774370386 0.3365899412382571 1.0 0.7167559314592846 41 P50897,Q9Y487,Q9BT22,Q9BV10,Q15043,Q5T8D3,Q9HC21,Q9H5K3 8 +Deep plantar creases 0.6224873270622957 0.9600533422864228 0.337028369052025 1.0 0.7167559314592846 5 Q9Y487,P61978,O00170 3 +Hypometric saccades 0.738660634824332 0.9594251256957924 0.3373446225004122 1.0 0.7167559314592846 3 P04062 1 +Focal t2 hyperintense basal ganglia lesion 0.3975101467165925 0.9592325046745688 0.3374416289432476 1.0 0.7167559314592846 24 Q9P0J0,Q7KZN9,P03886,P00846 4 +Stroke 0.3567834560249563 0.9589717847542236 0.3375729594258263 1.0 0.7167559314592846 34 Q96AA3,Q9H3H5,P00403,O75844,P03886 5 +Abnormal nasal mucosa morphology 0.7380701478639016 0.9570852198191232 0.3385242430817854 1.0 0.7170647051393779 3 Q13432 1 +Fever 0.3146469412098204 0.956821497580178 0.3386573596511597 1.0 0.7170647051393779 87 P14174,Q13586,Q8NBM4,P10253,P61978,Q14739,P03886,Q13144,P00403,P51572,P35610,Q9NR77,Q9NZ08,Q12769,P03915,P23786,Q9NZJ7,O15460,P00846,P49770,P07602,Q13510 22 +Abnormal myelination 0.2863777395746931 0.95623007580155 0.3389560081486318 1.0 0.7173655562757649 222 Q96CU9,Q9H3H5,Q99720,Q7KZN9,O96000,Q9BV10,Q9Y6M9,Q15067,O43676,P03886,Q86Y39,Q5H8A4,Q7LGA3,P41440,P40855,Q13144,Q9NPL8,P39210,P00403,P51572,Q9NR77,O15269,P29084,Q9P0J0,O75340,Q8TB36,P51648,Q5T8D3,Q9Y375,Q9H490,P03915,O43681,Q2TAA5,Q9NZJ7,Q9NWS8,Q9H0B6,P00846,P21912,O75306,O43819,P07602,Q9NX14 42 +Distal amyotrophy 0.3319598060897102 0.9546847038563702 0.3397371674721157 1.0 0.718355192135318 63 Q8N0X7,Q9BQT8,Q9NVI7,P39210,Q9H0B6,Q99720,Q9BUK6,P21912,P07196,Q9NR77,O15269,Q8TB36,P35637,Q13510,Q8N2K0 15 +Abnormal bleeding 0.2956676034607451 0.9536622520878018 0.3402546334848577 1.0 0.7190355751034134 106 Q9H3H5,Q8NBM4,Q9Y487,Q10469,Q14739,Q4KMQ2,Q96AA3,O75844,P11117,Q14108,P51798,P38435,Q9NWM8,Q8NCH0,Q9UHX1,Q96PU5,P23786,O15460,P21912,P04062,P21964,P49257 22 +Ecchymosis 0.4830988342250336 0.9489078864938008 0.3426674631283322 1.0 0.7218861223236865 11 P04062,Q8NCH0 2 +Diaphyseal thickening 0.7356565432400134 0.9475282042804632 0.3433696912985373 1.0 0.7221050873768249 3 Q14739 1 +Abnormality of the skull base 0.3321103643394231 0.9441105751601692 0.3451131458302556 1.0 0.7237458188640518 60 Q96AA3,Q9NPL8,Q9H490,Q9UBM7,O95298,Q9Y487,P15291,Q10713,Q9UHX1,P23786,Q96J42,Q14739,Q9H5K3 13 +Aplasia hypoplasia of the tongue 0.5839730282191723 0.9440780370484536 0.3451297717629753 1.0 0.7237458188640518 6 Q96J42 1 +Skeletal muscle atrophy 0.2821885609683963 0.9428302203944062 0.3457677514345112 1.0 0.7240101655228027 172 O43505,Q16637,O14979,Q13126,P50402,Q9BUK6,Q99720,P07196,Q9HC21,Q8N2K0,O75298,Q9NPL8,P39210,P55263,O60313,Q9NR77,O15269,Q6P4A7,P12235,Q8TB36,Q9H5K3,Q8N0X7,Q9BQT8,Q9NWM8,Q9NVI7,Q15165,Q3ZAQ7,Q9H0B6,Q6DKK2,P21912,P51812,O43819,Q969X5,P51530,P35637,Q13510,Q92804,P50416 38 +Muscle fiber inclusion bodies 0.4819287577159414 0.9420864124335474 0.3461484004342889 1.0 0.7240101655228027 11 O75340,Q9H3H5,P07196,O43676 4 +Deformed tarsal bones 0.6742803504380405 0.9417470397482374 0.3463221654596466 1.0 0.7240101655228027 2 O43175 1 +Abnormal aortic valve morphology 0.3424954261926078 0.9408327524465327 0.3467905736726184 1.0 0.7240101655228027 42 P04062,P51812,O75844,Q6NUK1,Q9UHX1,Q9BUB7,P21964,P37268 8 +Keratoconjunctivitis 0.4816728760579419 0.9405947252974426 0.3469125860162356 1.0 0.7240101655228027 11 Q14739,P29084,Q8NBM4 3 +Ophthalmoparesis 0.3161012666205134 0.9385113598149392 0.3479816818465286 1.0 0.7249953526447169 84 Q96CU9,Q13586,Q7KZN9,Q9BPX6,P03886,Q96IX5,P00403,O60313,P12235,Q9P0J0,Q96HR9,Q96DP5,Q9Y4W6,O00483,Q86SQ9,P03915,O00170,O15460,Q5JPH6,P00846,P21912,P04062,Q10713,O75306,Q8NCE2,O95169,O43819,P51530,P54098,O76024 30 +Abnormal heart valve morphology 0.3185316953084136 0.9380074739585216 0.3482405692020847 1.0 0.7249953526447169 81 P51798,P04062,Q8NCH0,P53701,P51812,O75844,Q6NUK1,Q9UHX1,P21964,Q9BUB7,P08236,Q96PU5,O95202,Q9Y4P3,Q9NX14,P37268,Q5H8A4 17 +Widened subarachnoid space 0.3759569496690956 0.9374918987361994 0.3485055890239814 1.0 0.725182837832826 29 P00403,Q9BV10,P03915,O75340,Q2TAA5,P03886,Q01105 7 +Anencephaly 0.4233049954479838 0.9367824816598626 0.3488704583219681 1.0 0.7252553262094582 16 Q8TAA9,Q96J42,P21964 3 +Hepatosplenomegaly 0.3459275078597222 0.9360255719147074 0.3492600216394568 1.0 0.7252553262094582 39 P51798,O75845,P04062,Q658P3,P10619,Q13510,Q14739 7 +Infectious encephalitis 0.4989280051104109 0.9359280113007687 0.3493102538385035 1.0 0.7252553262094582 9 Q9BUB7,Q14739,Q8NBM4 3 +Heterogeneous 0.3420307330548565 0.935886083589421 0.3493318430694618 1.0 0.7252553262094582 42 P00846,P51798,O75844,Q9NR77,P12235,P00367,P03915,P21964,Q8TB36,P40939,P03886,Q16836 12 +Aplasia hypoplasia involving bones of the thorax 0.3583754489996745 0.9332363007722349 0.3506979758771615 1.0 0.726776173353462 33 Q7Z4L5,Q7RTS9,O75844,Q9BV10,Q9UHX1,Q14739,P16435 7 +Centrally nucleated skeletal muscle fibers 0.5063714124129574 0.9298503224881332 0.3524485870764955 1.0 0.7273776111031991 8 Q13586,P22626,Q9BPX6,Q8NCE2 4 +Multiple prenatal fractures 0.5808684892993371 0.9296032714108264 0.35257653301183 1.0 0.7273776111031991 6 Q14739,O75718,Q32P28 3 +Hammertoe 0.4055864135421134 0.9292776151137884 0.3527452329123053 1.0 0.7273981355554379 20 Q8N0X7,P39210,Q9UBM7,Q99720,P07196,Q9NR77,Q8TB36 7 +Retinal arteriolar tortuosity 0.4794770450975639 0.9277953973475996 0.3535137119985299 1.0 0.728327260961 11 P00846 1 +Kyphosis 0.2919770221759749 0.9272828156603314 0.3537797141340131 1.0 0.7285477079379992 147 P50402,Q9Y487,Q10469,O95202,O75648,Q14739,Q5H8A4,Q7LGA3,Q8NBU5,Q7RTS9,O75844,Q9NR77,P29084,Q8TB36,Q14108,P51648,Q8N0X7,Q9Y375,Q9NWM8,Q8NCH0,Q9BT22,Q9UHX1,Q32P28,Q9H0B6,Q9UBM7,P21912,P04062,P51812,P51530,P08236 30 +Broad femoral neck 0.7299541816129446 0.9249975272147728 0.3549671937111542 1.0 0.7297507156203301 3 Q7RTS9 1 +Abnormal morphology of the conjunctival vasculature 0.5795678621971037 0.9235431051811572 0.3557242477971827 1.0 0.729987438534218 6 P10619,P18074 2 +Ventricular escape rhythm 0.6416164971951519 0.9228420698440286 0.3560895133616362 1.0 0.729987438534218 4 P50402 1 +Premature loss of primary teeth 0.6414293148896922 0.9220526030835002 0.3565011379868084 1.0 0.729987438534218 4 P17302,P51798 2 +Limited hip movement 0.4211547831168765 0.921795452101899 0.3566352801396908 1.0 0.729987438534218 16 O75844,Q7LGA3 2 +Adrenocorticotropic hormone deficiency 0.6695869837296606 0.9212570099516364 0.3569162601169728 1.0 0.729987438534218 2 O00170 1 +Hyperaldosteronism 0.6695869837296549 0.92125700995161 0.3569162601169866 1.0 0.729987438534218 2 Q01968 1 +Gastric ulcer 0.7289514866979284 0.921043143488392 0.3570279026091625 1.0 0.729987438534218 3 P04062,O76024 2 +Unusual infection by anatomical site 0.4447774886782979 0.9184059516130656 0.3584063760002189 1.0 0.730421594814572 14 Q14739,Q8NBM4,Q9BUB7,Q8TAA9,O15460 5 +Abnormal nipple morphology 0.3280393582930972 0.916861713440028 0.359215108884326 1.0 0.7312151936094119 65 Q96AA3,Q9H3H5,Q9NXE4,Q9UBM7,Q96A33,Q10469,Q9BV10,P29084,Q15067,O95202,Q9UM00,Q2TAA5,P23786,O14678,Q6NUK1,Q5H8A4,Q7LGA3 17 +Abnormal tongue morphology 0.3263091689414996 0.9141333920738296 0.3606467583449448 1.0 0.7333688946425517 68 O75431,Q9UBM7,P21912,Q96A33,Q10713,Q10469,O75844,O15460,Q9Y4P3,O75648,Q96J42,Q6NUK1,Q9H5K3,Q7LGA3 14 +Weakness of facial musculature 0.3273045209500482 0.9135465478313146 0.3609551641113471 1.0 0.7333688946425517 66 P40855,Q9H3H5,Q9BQT8,O75381,P51798,Q9BUK6,P51812,P07196,O60313,P12235,Q9UHX1,O75340,P56589,O43819,Q15043,P51530,Q86VD7,Q13510 18 +Subcutaneous nodule 0.40724867283925 0.9129522441844908 0.3612676585878867 1.0 0.7333688946425517 17 P11802,P21912,Q8NBM4,P35637,Q13510,Q9NZ08 6 +Decreased calvarial ossification 0.639257858983799 0.9128991984996966 0.3612955591121793 1.0 0.7333688946425517 4 O75844 1 +Spina bifida 0.3519108111322662 0.9112864508380352 0.3621444635268891 1.0 0.734223863663808 34 Q10713,P21964,Q9HC21,Q9UHX1 4 +Primary gonadal insufficiency 0.5386193254742082 0.9069710425910458 0.3644221105550049 1.0 0.7378067127452961 7 O76024,P49770,Q13144 3 +Abnormal spermatogenesis 0.4540348919100246 0.9048029664940892 0.3655697798235158 1.0 0.7384930258140124 13 P04062,Q13423,P16435 3 +Hypochromic microcytic anemia 0.7247645312372701 0.9045558857407574 0.3657007148782178 1.0 0.7384930258140124 3 O75027 1 +Anisopoikilocytosis 0.6367925535590718 0.9025186218303738 0.3667814338327808 1.0 0.7393985193724291 4 O75845 1 +Abnormal neuron morphology 0.3675085832000935 0.901446598457918 0.3673509148602596 1.0 0.7398689634680042 30 Q16637,Q99720,Q13510,Q92804,Q15165 5 +Pancreatic cysts 0.574335593116858 0.8991895597574924 0.3685517003649596 1.0 0.7410719024938305 6 Q96J42 1 +Abnormality of the parathyroid gland 0.3956875234832635 0.8950653412339583 0.370752159927961 1.0 0.7430952924438469 22 P03915,P03886,P21964,P00403 4 +Micropenis 0.3282594878411469 0.8947907836381831 0.3708989379788472 1.0 0.7430952924438469 59 O43505,Q9H936,P42892,Q9UBM7,Q9NX14,P53701,Q10713,P46977,Q9BV10,Q6NUK1,Q9NVI7,Q8TCJ2,P16435,O95470 14 +Slurred speech 0.4827198463663132 0.8944345039903012 0.371089458270224 1.0 0.7431125101231255 10 O15020,Q8N0X7,Q9Y487 3 +Anhidrosis 0.6063083095432744 0.8886730989446561 0.3741787926285407 1.0 0.7470532583110996 5 Q9Y276,Q12756 2 +Disproportionate tall stature 0.3660344542283579 0.8880694132656496 0.374503414347676 1.0 0.7473757162635242 30 Q9NWM8,Q8NCH0,O95202,P16435,Q5H8A4,Q7LGA3 6 +Abnormality of pancreas physiology 0.3387985428089051 0.8873440256581905 0.3748937094695812 1.0 0.7475034711878247 41 Q7Z2Z2,P14174,Q14739,Q8NBM4,P00403,P09601,Q15904,Q9UHX1,P03915,P03886,Q9NQH7 11 +Abnormal delivery 0.397335760902875 0.8859845917624589 0.375625830228572 1.0 0.7479011888873227 21 Q9UBM7,Q9Y487,O60313,O75844,Q969X5,O75718 6 +Retrognathia 0.3200433131481761 0.8842206901443359 0.37657709148246 1.0 0.7485906490152918 74 P04062,Q8NCH0,P37268,P53701,Q10469,Q15392,O75844,Q9BUB7,P29084,Q9UHX1,Q9NX14,Q6NUK1,Q7LGA3 13 +Abnormal caudate nucleus morphology 0.4719949785305498 0.8842104948479046 0.3765825940594167 1.0 0.7485906490152918 11 O95169,P00846,O75306,O43819 4 +Progressive hearing impairment 0.4154284620433917 0.8818896033622682 0.3778365098361123 1.0 0.7497821083018911 16 P03915,P03886,P00403 3 +Akinesia 0.4610957270873445 0.881371912791746 0.3781165547389649 1.0 0.7500130103090636 12 P04062 1 +Hypoplasia of teeth 0.3937464772952305 0.8798749560769382 0.3789270530676814 1.0 0.7506458094060164 22 P51648,O75431,P29084,O75844 4 +Ectrodactyly 0.4026753587882671 0.8758295279362028 0.3811227150793199 1.0 0.7523930549303938 18 Q9UBM7,Q99720,Q9NR77,O95202,Q8TB36,Q5H8A4 6 +Abnormality of cardiovascular system electrophysiology 0.2923901281217253 0.8750066283820996 0.3815702991465173 1.0 0.7526524023400827 123 Q9H3H5,P50402,Q9BTV4,Q10469,Q9BUB7,P10253,P40939,P03886,P40855,P00403,P13473,Q02978,P12235,P56589,P17302,P36551,Q8TB36,Q96DP5,Q16836,Q15056,Q9H490,O75208,P03915,P23786,Q9NZJ7,O15460,P42892,P00846,O75381,P21912,P04062,P53701,O75306,O43819,O95169,P07602,Q8NC56,Q9Y4P3,Q9NX14,P50416,P51970,O75880 42 +Pediatric onset 0.2830086642283255 0.8749366885523041 0.381608355050794 1.0 0.7526524023400827 232 Q96CU9,Q9H3H5,O75431,Q93063,P50402,Q9Y5L0,O95298,P07196,Q15904,O43292,Q8WWV3,O15020,Q9BRT2,Q9Y6M9,Q15067,O75648,Q9H9P8,Q9BUF5,P55795,Q8WVX9,P40939,Q13546,Q14566,Q96AA3,P41440,Q13144,Q9NPL8,Q5XKP0,P39210,Q12756,P55263,Q9NR77,Q9P0J0,O15118,P49366,Q6ZXV5,Q8TB36,Q9Y276,Q70HW3,Q96DP5,P20674,Q9Y4W6,Q9H5K3,Q9NSD9,P28288,Q8N0X7,Q9Y375,P51798,P49748,O75027,P22830,Q9Y6B6,Q92643,P23786,Q9NZJ7,Q2TAA5,O95831,Q9NVI7,Q5JPH6,O14773,Q9H0U3,Q10713,P49770,O75306,O95169,P07602,Q96S52,Q9Y320,Q13510,Q5JRA6,Q53H12,P51970,O75746,P54098 74 +Abnormality of the bladder 0.2921981425697703 0.8718891501129569 0.3832688532667825 1.0 0.7540308654651772 124 Q93063,Q99720,P07196,Q8TAA9,P61978,Q9BRK0,O75298,Q8WWI5,Q9NR77,P12235,Q3ZCQ8,P56589,P17302,Q96DP5,P22626,Q8N0X7,Q15056,Q9NWM8,Q8NCH0,Q9UBB4,Q86XL3,Q9UHX1,O43681,Q9NZJ7,O00170,O96011,P21912,P04062,Q9UJS0,P51812,P21964,Q8NCE2,P07602,P16435,P35637,Q9Y4P3,Q08209,P54098 38 +Vertebral compression fracture 0.4257352371655881 0.8701965492700311 0.3841930014043146 1.0 0.7547953127989112 15 Q7Z2Z2,P04062,Q14108,Q32P28,O75718,Q14696 6 +Abnormal pharynx morphology 0.33955191174787 0.8700479916058055 0.3842741778768863 1.0 0.7547953127989112 39 Q7RTS9,Q9H0U3,Q10469,Q9BV10,Q13432,Q03519,P08236,P17302,Q13510,O15460 10 +Hypoplasia of the corpus callosum 0.2774622137441258 0.8658425827529979 0.3865764936486227 1.0 0.7559659901926147 180 P49902,Q9H3H5,Q9BV10,Q96N66,P03886,Q5H8A4,Q7LGA3,P00403,Q9NZ01,Q9UBX3,Q9H490,Q9UHX1,P03915,Q96PU5,Q9NZJ7,P37268,P04062,P07602,Q9Y320,Q01105 20 +Abnormality of the extrinsic pathway 0.5301460660355941 0.8647809118387761 0.3871590498743986 1.0 0.7560826049762311 7 Q9H3H5,P38435 2 +Skin dimple 0.3676678213149015 0.863797199812246 0.3876993063866178 1.0 0.7560826049762311 29 Q9H3H5,Q08J23,P53701,Q969X5,Q8TAA9,O95202,Q9UM00,P61978,Q9Y4P3,Q9NX14,Q5H8A4 11 +Abnormal femoral neck head morphology 0.3324021527033215 0.8634908619965442 0.3878676414816697 1.0 0.7560826049762311 44 Q7Z2Z2,Q7RTS9,O75431,Q9Y487,Q96A33,P51812,Q10469,O75844,P29084,Q14739,O75718,Q7LGA3 12 +Large for gestational age 0.4938892933054742 0.8630554094276583 0.3881070028162583 1.0 0.7560826049762311 8 P31751,Q9UM00,Q8NCE2 3 +Spastic paraparetic gait 0.6002721349650704 0.8621677708723722 0.3885952021967629 1.0 0.7567119491991362 5 Q15041 1 +Bifid tongue 0.7134529244966058 0.8602312815184315 0.38966156436959 1.0 0.7575007585665936 3 Q9UBM7 1 +Myoclonic spasms 0.565066920461452 0.8561651540803372 0.3919064339640514 1.0 0.7605740281335382 6 P00846 1 +Gliosis 0.3331003992197555 0.8553547634124362 0.3923547787392714 1.0 0.7611217596034469 43 P00846,P04062,Q7KZN9,Q10713,O75306,O43819,O95169,P49770,P35637,Q13144 10 +Tonic seizure 0.3813759183816462 0.8538448346131926 0.3931909688474673 1.0 0.7620985699065546 25 P07602,Q01105,Q9NZJ7 3 +Increased urine alpha ketoglutarate concentration 0.5981193467230836 0.8527340937001302 0.3938067796264923 1.0 0.76245161703358 5 P21912 1 +Fat malabsorption 0.4837784786427023 0.8526159372880769 0.3938723215884949 1.0 0.76245161703358 9 Q7Z2Z2,Q96A33,Q14739 3 +Postaxial hand polydactyly 0.4561176462444811 0.8514307978690151 0.3945300896780603 1.0 0.7630644855996378 12 Q7Z4L5,O75845,Q10713,Q9UM00,Q96J42,Q14739 6 +Keratitis 0.456093361000985 0.8512848145500316 0.3946111582976654 1.0 0.7630644855996378 12 Q14739,P29084,Q8NBM4 3 +Abnormal diaphysis morphology 0.3209806615075907 0.846836349971791 0.3970863441352559 1.0 0.7664067518229749 68 O75431,Q13126,Q9Y487,Q14739,Q7LGA3,Q7Z2Z2,Q7RTS9,Q9NR77,P17302,O75718,Q8N0X7,P51798,Q32P28,P51812,P08236,Q9NX62,Q9Y4P3,Q96J42,P16435 19 +Abnormal pulmonary thoracic imaging finding 0.3893801814818227 0.8457113535542 0.397713787898442 1.0 0.7669716229590327 22 P04062,Q13510,P21964 3 +Abnormal arterial physiology 0.3733121147391203 0.8443294381284115 0.3984853403804278 1.0 0.7678724990193492 27 Q14739,Q9NWM8,Q8NBM4,O75844,Q9Y4P3,O15460 6 +Hyperhomocystinemia 0.6228276506204744 0.843974434795793 0.398683691655834 1.0 0.7678724990193492 4 P41440 1 +Oligomenorrhea 0.5956443744121876 0.8419020416750551 0.3998427874290577 1.0 0.769586514777655 5 P31751,O00170 2 +Abnormal circulating fatty acid anion concentration 0.4326425248224938 0.8400723579652468 0.4008678175384088 1.0 0.7704598741447103 14 P40939,Q16836,P23786,O75880 4 +Inappropriate antidiuretic hormone secretion 0.6501877346683275 0.8373934398282944 0.4023714520026882 1.0 0.7720544359616069 2 P50336 1 +Vomiting 0.2978905812860465 0.8353816787039782 0.4035028420891946 1.0 0.7735774152521714 95 Q96CU9,O96000,Q9Y6M9,P51571,O43676,O75648,P40939,Q13423,P03886,Q86Y39,Q9NPL8,P39210,P00403,P35610,P11117,Q16836,Q9Y375,P03915,P23786,Q9NZJ7,Q2TAA5,P00846,Q9UBM7,P07602,Q9NX14 25 +Abnormal anterior horn cell morphology 0.5241488400479336 0.8349971714601974 0.4037193009664175 1.0 0.7736686896813572 7 Q13510 1 +Intestinal polyp 0.4085624568887613 0.8340755518299144 0.4042384109406358 1.0 0.7740764639000185 16 P42892,O60566,Q8NFG4,P21912 4 +Dysphasia 0.3950223403211984 0.833327217990154 0.4046602099118006 1.0 0.7742202593154903 19 P53701,P21964,Q8NFG4,Q9H9P8,Q9NX14 5 +Tube feeding 0.3208545216910063 0.8330519051320184 0.4048154564373121 1.0 0.7742202593154903 66 Q9H490,Q99720,Q9UHX1,P07602,Q9NZJ7,Q96N66,Q01105,P37268,Q9NZ01 9 +Abnormality of subcutaneous fat tissue 0.4200238269108499 0.8319503683441392 0.4054369596773366 1.0 0.7744505206478913 15 Q9Y487,Q6NUK1,O75431,O75844 4 +Hyperpigmentation of the skin 0.3030083148794653 0.8315719729874702 0.4056505874005836 1.0 0.7744545797789474 90 P21912,P04062,P53701,O75844,P51648,Q14739,Q06136,P16615 8 +Aplasia hypoplasia of the nipples 0.3965652586841121 0.8311059281276963 0.4059137911156392 1.0 0.7746343152402577 18 Q5H8A4,Q96A33,Q10469,Q6NUK1 4 +Cholestasis 0.3135080118104323 0.8291726696506209 0.4070067076916088 1.0 0.77598703273227 77 Q9H3H5,Q15904,O75648,P40939,Q14739,P40855,Q8WWI5,P39210,Q16134,P55263,O15118,P56589,P36551,Q9Y276,Q9NSD9,P28288,Q9Y5U9,O75845,P49748,Q5JPH6,O96011,O75381,Q9UBM7,Q13510 24 +Weak cry 0.479361595180061 0.8283886487646166 0.4074504329613626 1.0 0.7760204094494253 9 O60313,O75208,Q13510 3 +Acantholysis 0.5925371447394823 0.8283241877208087 0.4074869282268261 1.0 0.7760204094494253 5 P16615 1 +Hemoglobinuria 0.6183469004383206 0.8252940008001148 0.4092046969500975 1.0 0.7767268808199204 4 P11413,Q9H0P0,Q969N2 3 +Polymicrogyria 0.3162213053455601 0.8247159200605102 0.4095328911799654 1.0 0.776856776350201 73 P40855,Q9Y487,Q10713,Q15392,Q9Y320,P23786,Q96N66,Q01105,P37268,Q9NZ01,Q9H5K3 11 +Abnormal thyroid hormone level 0.646745932415525 0.8226712964045172 0.4106949424183899 1.0 0.7782482324901003 2 O14654 1 +Abnormal electroretinogram 0.3427058974229797 0.821145942651175 0.4115631435081139 1.0 0.7795060929883948 34 P50897,P00846,O14773,Q96S66,Q15067,P40939 6 +Myotonia 0.521130915282666 0.8200380205274208 0.4121944330441307 1.0 0.7795060929883948 7 Q3ZAQ7,P50402 2 +Abnormal lumbar spine morphology 0.4605507029831157 0.8176782961883308 0.4135409066565367 1.0 0.7799215656971574 11 P04062,P51812,Q10469,O75845 4 +Thickened nuchal skin fold 0.4288099943631616 0.8153718094494133 0.4148595157541175 1.0 0.780351804838642 14 P40855,O96011,O75381,P56589,P61978 5 +Neurodegeneration 0.3577598627259291 0.8129833652537296 0.4162275956011041 1.0 0.7822620357031416 30 Q6DKK2,P08236,Q92804,P17900,Q15165 5 +Abnormal muscle glycogen content 0.6147047639672506 0.8101514391370561 0.4178531432860386 1.0 0.7840307545195041 4 O75648,Q9BUK6 2 +Wormian bones 0.3927169667833289 0.8075597109837426 0.4193440877294587 1.0 0.7860613120456491 17 Q12756,Q9Y487,O75844,Q8NC56,O95831,Q32P28,O75718,Q14696 8 +Saccadic oscillation 0.6139243473769819 0.8069118544042919 0.4197172685891583 1.0 0.7860613120456491 4 P04062 1 +Primary adrenal insufficiency 0.4161274960779908 0.805887407492445 0.4203077727000961 1.0 0.7860613120456491 15 P40855,O96011,O75381,P56589,Q9H0R6,Q13423,P16435,P50542 8 +Abnormality of the musculature of the upper arm 0.5538454745898664 0.8043204716900517 0.4212119176656204 1.0 0.7867181218890253 6 O14979,P50402 2 +Proximal upper limb amyotrophy 0.5538454745898664 0.8043204716900517 0.4212119176656204 1.0 0.7867181218890253 6 O14979,P50402 2 +Fatigable weakness of swallowing muscles 0.4268954504390978 0.8030427487433813 0.4219500265715776 1.0 0.786884420737065 14 Q15165,Q92804 2 +Bone pain 0.3838216079106191 0.8022467983482613 0.4224102104696117 1.0 0.7873573623953035 22 P04062,P07602,Q9NZJ7 3 +Hypocalcemia 0.4036551223256608 0.7999423420000448 0.4237442040083099 1.0 0.7879853663823361 16 P51798,Q9BV10,Q4J6C6,P21964,P40939 5 +Abnormality of earlobe 0.3677924244495414 0.7971481902070561 0.4253649715789018 1.0 0.7899461845707477 27 P53701,Q15392,P21964,Q9NX14,P16435,Q7LGA3 6 +Onset 0.2660101233868232 0.7969359085987283 0.4254882548058938 1.0 0.7899461845707477 399 O43505,O14979,O75431,P07196,Q15904,Q8WWV3,O15020,O75352,P50897,Q5XKP0,P55263,P46977,Q4J6C6,P17302,P36551,Q9Y276,P20674,Q9Y4W6,Q9H5K3,Q9NSD9,Q9UHX1,O75027,Q9NZJ7,O14773,P21912,P04062,Q9Y6M1,Q10713,P49770,O95169,P07602,Q13510,Q5JRA6,P51970,Q00535,Q9H3H5,Q13586,Q93063,O95298,Q9Y6M9,Q9HC21,Q96N66,Q5H8A4,Q7LGA3,Q96AA3,P39210,Q9P0J0,Q70HW3,Q9H490,P38435,Q96PU5,Q969X5,Q9Y320,Q9NWW5,P50402,O43292,Q15067,P08670,P40939,P41440,Q8IV08,Q9NR77,P12235,O15118,Q8TCJ2,Q8N0X7,P23786,Q9NVI7,Q6NUK1,Q9H0U3,Q9NQZ5,Q9NX14,Q96CU9,Q16637,Q9BUB7,P51571,O75648,Q8N2K0,Q14566,Q13144,Q8NBU5,Q9NPL8,Q8TB36,O14678,Q9Y375,P51798,P22830,Q92643,Q2TAA5,P31751,Q9NWS8,Q9UGP8,O75306,O43819,Q53H12 95 +Protruding tongue 0.4469163657178751 0.7961934248861466 0.4259196186584062 1.0 0.7904267690128868 12 Q6NUK1,Q10713 2 +Dysostosis multiplex 0.47335834675627 0.7955227286913021 0.4263094950994031 1.0 0.7906131483740596 9 P15586,P10619,P08236,P04066,Q9Y223 5 +Calcific stippling 0.6966674765817509 0.7951303331056374 0.4265376915715135 1.0 0.7906131483740596 3 O15228 1 +Abnormality of bone mineral density 0.2849220075230618 0.7944219179124671 0.426949848613938 1.0 0.7906458244534745 146 Q9H3H5,O75431,Q13126,Q93063,Q9Y487,O43292,Q15392,Q10469,O95202,Q9HC21,O15228,Q14739,Q5H8A4,Q7Z2Z2,O75844,P29084,P12235,P17302,Q14108,O75718,Q9NSD9,Q9Y375,Q9H490,O75845,P51798,Q9NWM8,Q8WVQ1,Q15043,Q9NZJ7,Q32P28,P04062,P07602,Q8NC56,Q13510,Q5JRA6,Q9Y4P3 36 +Abnormality of the common coagulation pathway 0.4254396485762938 0.7936729454462805 0.4273858542626021 1.0 0.7909054863615683 14 P49257,Q4KMQ2,Q9BV10,P38435 4 +Abnormality of the vertebral endplates 0.5153613115302237 0.7914999125304107 0.4286523271710067 1.0 0.7926089439457438 7 Q7RTS9,O15228 2 +Large basal ganglia 0.413848899806386 0.7906593620055514 0.4291427962336884 1.0 0.7928759243317582 15 Q9NZ01 1 +Intestinal malrotation 0.3668921102780715 0.7894566392169099 0.4298451632330828 1.0 0.793214070855411 27 Q9UBM7,Q8NCH0,Q15392,Q9BV10,P21964,O95202,Q14739 7 +Progressive spasticity 0.3899467485917217 0.7875015524918465 0.4309883199640922 1.0 0.794363830279755 17 O60313,O43681,P07602,Q9NZJ7,P17900 5 +Hemiplegia hemiparesis 0.3350540966893766 0.7863969790765448 0.431634952734071 1.0 0.7945420942524934 35 P00403,Q8NBM4,O60313,P03915,P50416,P03886 6 +Temporal pattern 0.5142580161312386 0.7860524855084521 0.4318367390712054 1.0 0.7945420942524934 7 P04062,Q9NR77 2 +Mediastinal lymphadenopathy 0.5498321784895969 0.7858556426021629 0.4319520638985075 1.0 0.7945420942524934 6 Q9H0U3,O15460 2 +Abnormal atrioventricular valve morphology 0.3340562716223584 0.78423984755797 0.4328993877647575 1.0 0.7956458061524745 36 O75431,P04062,P53701,P51812,O75844,P21964,Q9Y4P3,Q9NX14 8 +Self mutilation 0.4448699339319468 0.7839318526883674 0.4330800982933245 1.0 0.7956587852365729 12 Q10713,Q10469,Q9UM00 3 +Impaired tactile sensation 0.4707451000391885 0.7812421204801065 0.4346601048116749 1.0 0.7966450400988377 9 P39210,Q9NR77 2 +Osteolytic defects of the distal phalanges of the hand 0.6074825682000765 0.780243564214696 0.4352475244432838 1.0 0.7970574637974472 4 O75844 1 +Hyperinsulinemic hypoglycemia 0.6073216145158116 0.7795789397859628 0.4356387561449821 1.0 0.7970574637974472 4 P40939,Q16836 2 +Recurrent bronchitis 0.6069180360745018 0.7779128254335752 0.4366204067898369 1.0 0.7975864605284942 4 Q03519 1 +Aplasia hypoplasia of the capital femoral epiphysis 0.5480584521369831 0.7777093449748943 0.4367403818127437 1.0 0.7975864605284942 6 Q7LGA3 1 +Abnormality of neutrophil morphology 0.5806564366541251 0.7766511316273861 0.4373646258088075 1.0 0.7980902889111733 5 Q14739 1 +Loss of ability to walk 0.4435675877161918 0.776133883833446 0.4376699389772285 1.0 0.7983294826407886 12 P00846 1 +Secondary microcephaly 0.3108382058711178 0.7726577385281425 0.439724963988058 1.0 0.8004345723522769 75 Q96CU9,P50897,Q5XKP0,Q9Y487,Q9BT22,Q10469,Q9BV10,Q9UHX1,Q15043,Q9HC21,Q5T8D3,Q86Y39,Q9H5K3 13 +Bowing of the legs 0.3181904225691658 0.772581079091301 0.4397703457808852 1.0 0.8004345723522769 50 Q7Z2Z2,Q7RTS9,Q8N0X7,O75431,Q13126,P51798,Q9NR77,P08236,Q9NX62,Q9Y4P3,Q32P28,P16435,O75718,Q7LGA3 14 +Macular purpura 0.4428531570496573 0.7718579696074825 0.4401985532342451 1.0 0.8004345723522769 12 P04062,Q8NCH0 2 +Abnormality of the extraocular muscles 0.6342302878598358 0.7695959391189195 0.4415396146448687 1.0 0.8004345723522769 2 P54098 1 +Macular atrophy 0.5460496638458349 0.7684947054029533 0.4421933349965159 1.0 0.8004345723522769 6 P04062 1 +Corpus callosum atrophy 0.4104329285031552 0.7678526064095393 0.442574756756573 1.0 0.8004345723522769 15 O75503,P54886,P51572,O60313,Q9H9P8,Q8WVX9,P51970 7 +Cirrhosis 0.3306271766788795 0.7674053813334287 0.4428405300065841 1.0 0.8004345723522769 38 P04062,Q14739,Q10713,P39210 4 +Abnormality of the protein c anticoagulant pathway 0.6042967495431295 0.7671045803532525 0.4430193388629257 1.0 0.8004345723522769 4 Q9H3H5 1 +Reduced protein s activity 0.6042967495431293 0.7671045803532525 0.4430193388629257 1.0 0.8004345723522769 4 Q9H3H5 1 +Subcutaneous hemorrhage 0.3313210777557001 0.7651528978854263 0.4441805038077178 1.0 0.8015892353079808 37 P38435,P04062,Q8NCH0,P21964,Q14108 5 +Preaxial polydactyly 0.4414615900429043 0.7635332339528778 0.4451454500558411 1.0 0.8023825539558869 12 Q96J42,O95202,Q5H8A4,Q9UHX1 4 +Abnormality of the wrist 0.340532817088543 0.7618162930442652 0.4461696547101503 1.0 0.8035964457082975 33 Q7RTS9,O75844,Q9BV10,Q969X5,Q13510,Q9H6K4 6 +Decreased light and dark adapted electroretinogram amplitude 0.687465922702146 0.7598384917500743 0.4473511315184439 1.0 0.8044595308545959 3 P50897 1 +Abnormal aortic arch morphology 0.4494279020638577 0.7532636325450193 0.4512915080551827 1.0 0.8083728263912616 11 Q9UHX1 1 +Absent epiphyses 0.5075110837109474 0.7528158841619672 0.4515605603148445 1.0 0.8085386820486977 7 Q7LGA3 1 +Laryngeal dystonia 0.6854460093896639 0.7521328912155453 0.4519711458679101 1.0 0.8089577306120171 3 Q96RL7,O75569 2 +Narrow nasal ridge 0.5421771120227314 0.7507659850797793 0.4527935037289543 1.0 0.8094810121287821 6 O75844 1 +Abnormality of the anterior fontanelle 0.3465826067338423 0.750432414611008 0.4529943145366641 1.0 0.8095241611571744 31 P40855,O96011,O75381,Q16134,Q08J23,Q9Y487,P51812,Q6NUK1,P56589,P42345,Q32P28,P20674,P16435,O75718 14 +Bird like facies 0.5065664076798759 0.7481733224595024 0.4543556200688257 1.0 0.8106293777385813 7 O75844 1 +Occipital encephalocele 0.5740113023943245 0.7479383356034474 0.4544973529922338 1.0 0.8106293777385813 5 Q9H5K3 1 +Cortical dysplasia 0.3618481099852601 0.7463972071669618 0.4554275058560948 1.0 0.8116564884607649 27 Q96N66,Q9NZ01 2 +Paresthesia 0.3676316329029138 0.7406599665097788 0.4588996385951045 1.0 0.8140303798081486 25 Q9NZ08,Q8NBM4,P07196,Q9NR77,Q9H6K4,O00170,O15460 7 +Metatarsus valgus 0.6823573217964645 0.7403806197491685 0.4590690749507324 1.0 0.8140303798081486 3 Q9H5K3 1 +Polydactyly 0.3195565838167265 0.7391028016199119 0.4598445757654774 1.0 0.8141370084852168 45 Q7Z4L5,O75845,Q10713,Q9UHX1,P21964,Q96J42,Q14739,Q5H8A4 8 +Adducted thumb 0.3673529433240926 0.7383692875047999 0.4602900725398005 1.0 0.8141370084852168 25 Q96AA3,Q8NBU5,P42892,Q8NCH0,Q86XL3,Q9Y4P3 6 +Bone spicule pigmentation of the retina 0.4703609359242816 0.737940411535672 0.4605506604089222 1.0 0.8141370084852168 8 Q9UG56 1 +Atelectasis 0.4466007372655453 0.7369437335318989 0.4611565670859932 1.0 0.814893710138072 11 P21964 1 +Abnormality of the curvature of the vertebral column 0.2705122948786457 0.7352727637403287 0.4621733921480853 1.0 0.8160670891873325 324 Q96CU9,Q9H3H5,P50402,Q99720,Q9BUK6,Q9Y487,Q10469,Q9BV10,Q8TAA9,O95202,P51571,O15228,O75648,Q14739,Q5H8A4,Q7LGA3,Q8NBU5,Q7RTS9,Q96A33,O75844,Q9NR77,P29084,O75340,Q8TB36,Q14108,P51648,Q9UM00,Q9H5K3,Q7Z4L5,Q8N0X7,Q9BQT8,Q9H490,Q9Y375,O14653,Q9NWM8,Q8NCH0,Q9BT22,Q9UHX1,Q9UG56,Q96PU5,Q15043,Q2TAA5,Q9NVI7,Q6NUK1,Q32P28,Q3ZAQ7,Q9H0B6,Q9UBM7,P21912,P04062,P51812,Q10713,P21964,Q969X5,P51530,P08236,P35637,Q9Y4P3,Q13510,P16435,Q01105 61 +Protuberant abdomen 0.5386901674399931 0.7348446508865806 0.4624341102697409 1.0 0.8160670891873325 6 P04062 1 +Generalized abnormality of skin 0.2758727358892579 0.7347257857158137 0.4625065129863246 1.0 0.8160670891873325 221 P14324,Q9H3H5,O75431,Q13126,Q9Y487,Q15904,O75648,Q14739,P03886,Q06136,P40855,Q8WWI5,P39210,P00403,O75844,P29084,O15269,O15118,P56589,P17302,Q14108,P51648,P98194,P51798,P38435,Q9NWM8,Q8NCH0,P22830,P03915,P37268,Q6NUK1,P00846,O75381,Q9UBM7,P21912,P04062,P53701,P10619,P51812,O75306,P21964,Q9Y4P3,Q9NX14,P49257 44 +Abnormal endocrine physiology 0.5705539748118957 0.7330597121105953 0.4635220108863442 1.0 0.8171624529614552 5 Q13423 1 +Hydrops fetalis 0.3229433063825553 0.7325031778847937 0.4638615037711875 1.0 0.8171624529614552 42 P04062,Q9BT22,O96000,P10619,Q13510,Q14739 6 +Lipodystrophy 0.3296464705990502 0.7324573038384772 0.4638894936930837 1.0 0.8171624529614552 35 P31751,Q9H3H5,P50402,Q9Y487,O75844,P42167,Q6NUK1 7 +Multifocal epileptiform discharges 0.3634244927865928 0.7315130772929243 0.4644658197620934 1.0 0.8171624529614552 26 Q96N66,Q9UBX3,Q9NZ01 3 +Chronic rhinitis 0.6799607905446248 0.7312880654198971 0.4646032186681901 1.0 0.8171624529614552 3 Q9BV10 1 +Abnormality of circulating leptin level 0.5955056700943067 0.7310349615024304 0.4647577984286566 1.0 0.8171624529614552 4 O75844 1 +Abnormal midbrain morphology 0.4686494437878553 0.7288981032758057 0.4660639951144119 1.0 0.8191336430764338 8 P04062 1 +Aplasia hypoplasia of the skin 0.314738072265841 0.7286143975471366 0.4662375689968003 1.0 0.8191336430764338 55 O75431,Q9NWM8,Q8NCH0,P53701,Q15392,O75844,O95202,Q96PU5,Q9NX14,Q5H8A4 10 +Ventricular septal hypertrophy 0.6780068226319138 0.7238919445466763 0.4691320758207711 1.0 0.8214242983894696 3 Q8NC56 1 +Coloboma 0.3136405221286754 0.7225301009677142 0.4699686257043334 1.0 0.8214242983894696 49 Q9UBM7,P53701,Q10713,Q9UHX1,O75340,O95202,Q9NX14,Q5H8A4,Q9H5K3 9 +Skin vesicle 0.4438881845211467 0.7213093258742643 0.4707192204149515 1.0 0.8216216101989994 11 P16615 1 +Limb pain 0.443667607543234 0.7200390681326206 0.4715009415490754 1.0 0.821662911187206 11 P00846,P54886,O75569,O15269,P36551,Q8WVX9 6 +Abnormal nerve conduction velocity 0.3239839422312013 0.7194913359983035 0.4718382386104172 1.0 0.821662911187206 40 Q99720,Q9UBB4,Q9NR77,O15269,O43681,P07602,Q8TB36,Q9NZJ7,Q8N2K0 9 +Oculomotor apraxia 0.367237273172404 0.7141800294029982 0.4751158641719133 1.0 0.823055156762082 24 P04062,Q10713,O43292,O14773 4 +Cholestatic liver disease 0.5912947116639011 0.7138617173541734 0.4753126917148402 1.0 0.8230849408304604 4 P40939 1 +Abnormal gastrointestinal motility 0.3463698476369922 0.7097932577776934 0.4778323506936113 1.0 0.8263105628472364 30 P11802,Q9UBM7,P00403,P03915,P35637,P36551,P61978,P03886,P54098,Q01844 10 +Nonketotic hypoglycemia 0.5651024902720005 0.7096893979699576 0.4778967681242201 1.0 0.8263105628472364 5 P31751,P23786,P49748 3 +Difficulty running 0.4118604614335839 0.7065492800004032 0.4798466178629286 1.0 0.8284291645650268 14 Q9H3H5,P07196,Q9BPX6,O75340,Q3ZAQ7 5 +Cold induced muscle cramps 0.6731670848086626 0.705641854097798 0.4804108891086582 1.0 0.8287612715236191 3 Q9NR77 1 +Eeg with focal spikes 0.5640337983344534 0.7051215252123059 0.4807346120599489 1.0 0.8287612715236191 5 Q5H8A4 1 +Aplasia hypoplasia of the 5th finger 0.4006176463107711 0.7025111575850546 0.4823604459506021 1.0 0.8303887960238011 15 P13073 1 +Heinz bodies 0.6179599499374125 0.7018180944731277 0.4827926129653876 1.0 0.8303887960238011 2 P11413 1 +Increased ldl cholesterol concentration 0.448305241125559 0.7008824420952185 0.4833763826595763 1.0 0.8304576622970298 10 Q8N511 1 +Hyperlipoproteinemia 0.448305241125559 0.7008824420952185 0.4833763826595763 1.0 0.8304576622970298 10 Q8N511 1 +Scanning speech 0.6712102920849699 0.6982918511880778 0.4849946943119159 1.0 0.8323017563060668 3 O14773 1 +Abnormal exteroceptive sensation 0.311693442212291 0.6937669980679194 0.4878283420769502 1.0 0.8347151998869834 53 P39210,Q8NBM4,Q8NCH0,P07196,O00170,Q9NR77,O15269,O95831,O15460,P07602,Q9H6K4,P61978,Q9NZ08,Q9NZJ7,Q8WVX9,P54098 16 +Abnormal renal medulla morphology 0.4468445825093903 0.6927424353384998 0.488471203232486 1.0 0.8347151998869834 10 Q7Z4L5 1 +Arm dystonia 0.5860685321984251 0.6926496235576937 0.4885294604699268 1.0 0.8347151998869834 4 Q99720 1 +Disproportionate short trunk short stature 0.5609846037367399 0.6921140330157763 0.4888657196721904 1.0 0.8348558998765768 5 Q9UHX1 1 +Bradykinesia 0.3519612560720359 0.691640899743442 0.4891628701104678 1.0 0.8348558998765768 28 Q5JPH6,Q86SQ9,Q6DKK2,P04062,O75569,P12235,Q15043,P54098,Q96IX5 9 +Truncus arteriosus 0.4537006177485633 0.6885990934316781 0.4910755917329883 1.0 0.8356970893910985 9 Q9UHX1 1 +Thin ribs 0.4088652789503582 0.6874161966405178 0.4918204939621151 1.0 0.8356970893910985 14 O75431,O75844,Q8NCE2,O95831,Q32P28 5 +Supraventricular arrhythmia 0.3873673629145012 0.6870939754233251 0.4920235104482051 1.0 0.8356970893910985 16 P00846,P50402 2 +Central nervous system cyst 0.3110901855841467 0.6867542622206066 0.4922375964929668 1.0 0.8356970893910985 53 Q9UBM7,P00846,Q9Y487,P15291,Q9UHX1,O95202,P23786,Q96J42,Q9H5K3 9 +Decreased circulating level of specific antibody 0.4606301234818052 0.6866691092480239 0.4922912674218844 1.0 0.8356970893910985 8 Q9H0U3,Q9BV10,Q13546 3 +Nephrotic syndrome 0.3512557740773661 0.6855226919113904 0.4930141464039035 1.0 0.8356970893910985 28 Q12769,Q8NCH0,Q9BT22,Q14108,O95470 5 +Recurrent sinusitis 0.5594187702930139 0.685449488055545 0.4930603247575509 1.0 0.8356970893910985 5 Q13432 1 +Pes valgus 0.4375226768149765 0.6847231943450356 0.4935186098583088 1.0 0.8356970893910985 11 Q5H8A4,Q9UHX1 2 +Reduced subcutaneous adipose tissue 0.4527368954029897 0.6833918015722348 0.4943592991567209 1.0 0.8359152604231785 9 Q6NUK1,O75844 2 +Frontotemporal dementia 0.4450822550273363 0.68293252370188 0.4946494812928246 1.0 0.8359152604231785 10 P35637,O96008 2 +Quadriceps muscle weakness 0.5587488070423441 0.6826011795545194 0.4948588885413312 1.0 0.8359152604231785 5 P12235 1 +Mutism 0.3751347100471149 0.6806216323900225 0.4961109353001889 1.0 0.8359322549458201 17 Q9NX14,P53701,Q13510 3 +Hypertriglyceridemia 0.3725144663004039 0.6798024581015066 0.4966295500357338 1.0 0.8359322549458201 20 P31751,O75431,P50402,Q9BTV4,P22830,O95470 6 +Arthralgia 0.3242891810350487 0.6791128385624278 0.4970663683455496 1.0 0.8359903150590229 35 Q15056,P14174,Q15800,Q8NBM4,Q9Y4P3,Q13510,Q9NZ08,O15460 8 +Nonprogressive cerebellar ataxia 0.5826289725108837 0.6787537472387509 0.4972939047342641 1.0 0.8359903150590229 4 O75027 1 +Abnormality of the lens 0.2723839321397346 0.678160949711264 0.4976696492209389 1.0 0.8359903150590229 211 O43505,Q9H3H5,O14979,Q13126,Q8NBM4,Q08J23,Q8WWV3,Q9BUB7,O15228,P08670,Q8N2K0,P03886,Q12797,Q06136,Q7LGA3,P40855,Q15800,P52732,Q16134,P00403,O60313,P29084,P12235,O75340,P56589,P17302,Q6ZXV5,Q9Y276,Q96HR9,Q9NZ08,P22626,Q9H5K3,Q86SQ9,Q15056,O75845,Q03519,P03915,O60566,Q8TC12,P23786,Q9NVI7,P04439,O96011,O75381,Q9UBM7,P21912,Q9UJS0,P53701,Q9Y287,Q10713,P51812,Q53H12,P21964,Q8NC56,Q9Y4P3,Q9H6K4,Q9NX14,Q96J42,P48449,P54098 60 +Coxa valga 0.3722910270394364 0.6781269501826569 0.4976912043910242 1.0 0.8359903150590229 20 P51812,Q96A33,Q8WVQ1,Q10469,P29084,O75844 6 +Increased adipose tissue 0.5824598117217438 0.6780717072490835 0.4977262286078163 1.0 0.8359903150590229 4 P31751 1 +Partial agenesis of the corpus callosum 0.4064478271237401 0.6720008562556924 0.501583151211145 1.0 0.8380326814465309 14 Q15392,Q9HC21 2 +Abnormality of the anus 0.3159744770025793 0.6710906961446734 0.5021627535778892 1.0 0.8380326814465309 43 P53701,P21964,Q9NX14,Q6NUK1,P16435,P16615 6 +Abnormal greater sciatic notch morphology 0.5540215472080594 0.6625599067367193 0.5076124552831671 1.0 0.8436272289109437 5 Q7RTS9 1 +Slow saccadic eye movements 0.4331602559116743 0.6597438407742724 0.5094182276845691 1.0 0.8463213630350601 11 P04062,Q8WWI5,Q8IV08 3 +Hypoplastic nipples 0.4328429219783807 0.6579300442952009 0.5105830839035237 1.0 0.8469662611861924 11 Q96A33,Q6NUK1 2 +Hydrocele testis 0.5214645349194623 0.6568654127125167 0.5112674594560582 1.0 0.8469662611861924 6 Q9UBX3 1 +Oral ulcer 0.4548505151797895 0.6563942393420082 0.5115704959967009 1.0 0.8469662611861924 8 Q7Z2Z2,Q9NZ08,Q8NBM4 3 +Difficulty standing 0.4876663004114604 0.6559757679906761 0.5118397156753747 1.0 0.8469662611861924 7 Q7RTS9 1 +Optic nerve dysplasia 0.6595478263522012 0.6548522847941926 0.512562863730069 1.0 0.8477939715687363 3 O43505 1 +Myopia 0.2762913984305172 0.6505742206327408 0.5153213760587934 1.0 0.8484559830728686 103 P49902,Q9Y487,O43292,Q15067,P40939,Q7Z2Z2,P29084,P12235,P17302,P51648,Q9H5K3,Q9NWM8,Q8NCH0,Q9UHX1,Q9NVI7,O15460,P21912,Q53H12,O43819,Q9Y4P3,Q9NX14 21 +Aplasia hypoplasia of the femur 0.3819540074582687 0.649810595802683 0.5158145737834752 1.0 0.8484559830728686 16 O75431,Q8WVQ1,Q9BV10,Q9UHX1,O95831 5 +Primitive reflex 0.5198793005785731 0.6497524350611058 0.5158521477421556 1.0 0.8484559830728686 6 P17900 1 +Abnormal pulmonary valve morphology 0.3925159558808622 0.6488575426407597 0.5164304598223541 1.0 0.8484559830728686 15 Q9BUB7,P21964 2 +Intellectual disability mild 0.2788299673259669 0.6484643119971059 0.5166846860329459 1.0 0.8484559830728686 133 Q9BUK6,Q15904,O43292,Q8WWV3,O75648,Q96N66,Q7LGA3,Q15800,Q7RTS9,P35610,Q6P4A7,Q9NZ01,Q9H5K3,Q8N0X7,Q9BT22,Q6NUK1,P16615,P00846,P51812,Q10713,P21964,Q01105 22 +Abnormality of peripheral nerves 0.3098526994562801 0.6479231534821421 0.5170346545930791 1.0 0.8484559830728686 46 P39210,Q99720,Q9UBB4,Q9NR77,O15269,O43681,P07602,Q8TB36,Q9NZJ7,Q8N2K0 10 +Abnormal subarachnoid space morphology 0.3319150721870925 0.645797389290926 0.5184105789841182 1.0 0.8492517958188165 32 P00403,Q9BV10,P03915,O75340,Q2TAA5,P03886,Q01105 7 +Abnormal blistering of the skin 0.3653937327980907 0.64127912082739 0.5213413520795271 1.0 0.8522247860251135 21 P51798,Q8NBM4,P17302,P36551,Q06136 5 +Dystrophic fingernails 0.4371614016300671 0.6390074884419743 0.5228180603672232 1.0 0.8530110330082203 10 O75844 1 +Supernumerary bones of the axial skeleton 0.5173855404777947 0.6385868791841675 0.5230917191456066 1.0 0.8530110330082203 6 Q9UHX1 1 +External ear malformation 0.368465921418406 0.6368315676546832 0.5242345614343715 1.0 0.8530540364976824 19 P40855,O96011,O75381,Q12756,Q8NCH0,P56589,P17302,P50542 8 +Polyhydramnios 0.3066463116787953 0.6364930803798239 0.5244550896582216 1.0 0.8530540364976824 52 P51798,P04062,O75844,Q9BV10,P21964,Q9UM00,Q70HW3,Q9NVI7,Q14739 9 +Eeg with focal epileptiform discharges 0.3183866833123844 0.6340728616919269 0.526033272646943 1.0 0.8542542499799949 37 Q96N66,Q9UBX3,Q5H8A4,Q9NZ01 4 +Pleuritis 0.5708645991232459 0.6316466762977662 0.5276177791178251 1.0 0.8551625977778121 4 Q8NBM4 1 +Pulmonary embolism 0.5708645991232459 0.6316466762977662 0.5276177791178251 1.0 0.8551625977778121 4 Q8NBM4 1 +Orchitis 0.5708645991232459 0.6316466762977662 0.5276177791178251 1.0 0.8551625977778121 4 Q8NBM4 1 +Decreased cervical spine flexion due to contractures of posterior cervical muscles 0.5462980503364755 0.6300412839854669 0.5286675738764814 1.0 0.8557577315375803 5 P50402 1 +Adenocarcinoma of the small intestine 0.600125156445547 0.6293950886476083 0.5290904325332397 1.0 0.8559790243905182 2 Q6PD74 1 +Abnormal substantia nigra morphology 0.6522115179777265 0.627870664972496 0.5300886694518567 1.0 0.8559790243905182 3 P04062 1 +Coarse hair 0.3655189334617346 0.6274618108732207 0.5303565616240355 1.0 0.8559790243905182 20 Q9Y487,Q96A33,P51812,Q9Y276,Q9UM00,Q6NUK1 6 +Generalized joint laxity 0.4184174411972433 0.626662368416399 0.5308805763331672 1.0 0.8559790243905182 12 Q8NCH0,Q9UHX1 2 +Emg axonal abnormality 0.6517873798508693 0.6263193982804199 0.5311054652567129 1.0 0.8559790243905182 3 Q9Y223 1 +Beaking of vertebral bodies 0.4342141314521478 0.6227397224327641 0.5334555749070136 1.0 0.858867165296038 10 Q7RTS9,Q9UM00 2 +Abnormality of the musculature of the limbs 0.269469039462811 0.622725607250773 0.5334648521240777 1.0 0.858867165296038 165 Q9H3H5,O14979,Q16637,Q13126,P50402,Q99720,O95298,Q9Y487,Q15067,Q9HC21,P40939,Q14739,O75298,Q7RTS9,P39210,O60313,Q9NR77,O15269,P12235,O75340,Q8TB36,Q9H5K3,Q8N0X7,Q9BQT8,Q2TAA5,Q9NZJ7,Q3ZAQ7,P00846,P21912,P05023,O43819,Q969X5,P07602,P51530,Q13510 35 +Muscular hypotonia of the trunk 0.2935536766638323 0.6220871122525637 0.5338845888368691 1.0 0.8591978406873907 84 Q9H3H5,Q9NVI7,Q5XKP0,Q9NX14,O95298,O60313,P07602,Q96PU5,Q15043,Q9HC21,Q9NZJ7,Q2TAA5,Q96N66,P17900,O75880 15 +Neuroinflammation 0.5443132021588665 0.6217323867790643 0.5341178519254464 1.0 0.8591978406873907 5 Q9NZ08,Q8NBM4 2 +Unilateral renal agenesis 0.3663402212969349 0.6212282506678836 0.5344494541199134 1.0 0.8591978406873907 19 P16435,Q86XL3,Q9UHX1,Q7LGA3 4 +Ventriculomegaly 0.2649654119148066 0.6207747004210853 0.5347478715525491 1.0 0.8591978406873907 177 Q96CU9,Q9Y487,Q15392,Q9BV10,O95202,Q9HC21,Q9NPL8,P29084,O75340,Q9UM00,Q9H5K3,Q8NCH0,Q86XL3,Q9UHX1,P23786,Q9NZJ7,P00846,Q9UBM7,P04062,P51812,Q10713,P15291,P05023,O75306,O43819,P07602,Q9Y320,Q9NX14,Q96J42,Q01105 30 +Abnormal conjugate eye movement 0.2663834998184429 0.6207025692618902 0.5347953386382449 1.0 0.8591978406873907 321 Q96CU9,Q9H3H5,Q99720,Q7KZN9,O96000,Q9Y487,Q15392,Q9BV10,Q9Y6M9,Q15067,O95202,P51571,O43676,O75648,P40939,Q14739,P03886,Q86Y39,O95470,Q5H8A4,Q7LGA3,P40855,Q9NPL8,P51572,O60313,P29084,P12235,Q9P0J0,O15118,O75340,Q9UM00,Q9H5K3,Q9H061,Q9Y375,Q9H490,P38435,Q8NCH0,Q9BT22,Q9UHX1,Q8NI60,Q96PU5,Q2TAA5,Q9NZJ7,Q9NVI7,Q6NUK1,O75381,Q9UBM7,P04062,P51812,Q10713,O75306,P21964,O43819,P07602,P35637,Q9Y4P3,Q9NX14,P16435 58 +Impairment of activities of daily living 0.3053659421613104 0.6190670902475804 0.5358721623650362 1.0 0.8606260946220105 58 Q8WWI5,Q99720,Q9UBB4,P07196,P51812,O15269,P21964,Q8TAA9,O43681,P07602,P35637,Q9NZJ7,O75298 13 +Limited elbow movement 0.3181651300529187 0.6183113354489383 0.5363701311751492 1.0 0.8608223961627088 35 Q7RTS9,P50402,Q969X5,P23786,Q9H6K4,P37268,Q7LGA3 7 +Decreased head circumference 0.2691275471607536 0.6139209679256065 0.5392675536348923 1.0 0.8636574382226762 459 Q96CU9,Q9H3H5,Q99720,O95298,Q7KZN9,O96000,Q9Y487,Q15392,Q9BV10,Q10469,Q9Y6M9,Q9BPX6,Q9BUB7,O95202,Q9HC21,O43676,O15228,Q96N66,P51571,P03886,Q86Y39,Q06136,Q5H8A4,O95470,Q7LGA3,P50897,Q96AA3,Q15800,P40855,Q5XKP0,Q7RTS9,Q13144,P51572,Q96A33,P46977,O75340,P51648,Q5T8D3,Q8TCJ2,Q9NZ01,Q9H5K3,Q8N0X7,Q96JX3,O75845,Q9BT22,Q86XL3,Q9UHX1,Q9UG56,Q15043,P23786,Q9NZJ7,Q6NUK1,O75381,P21912,P04062,P53701,O75648,Q10713,P21964,P07602,Q9Y320,P51530,Q9NX14,Q96J42,P16435,Q01105 66 +Abnormal response to endocrine stimulation test 0.647830771080552 0.6118954193044022 0.5406069524952579 1.0 0.8648956202280976 3 Q13423 1 +Generalized muscle weakness 0.3247892190835907 0.6111814065982955 0.5410794912558878 1.0 0.8649813799134786 33 P21912,P12235,P35637,P10253,Q92804,O95831,P40939,Q15165,P54098 9 +Lower limb amyotrophy 0.364220904157123 0.6056986676475588 0.5447148689257326 1.0 0.8663254180554345 19 Q9H0B6,Q9NR77,O75298 3 +Scaling skin 0.4766764314824974 0.6030927810453884 0.5464469685626747 1.0 0.8687183593832658 7 O75352,O75844 2 +Abnormal ureter morphology 0.35072180520819 0.6022688229701114 0.5469952102384317 1.0 0.8688717342670668 25 Q96J42,O75844,P23786,Q7LGA3 4 +Focal white matter lesions 0.5091774983783937 0.602056145349634 0.5471367649530068 1.0 0.8688717342670668 6 P54098,P12235 2 +Neuronal loss in basal ganglia 0.509107084129892 0.6017442948336992 0.5473443602848431 1.0 0.8688717342670668 6 O75306,O43819 2 +Expressive language delay 0.422279783719116 0.5978393884593995 0.5499471059713157 1.0 0.8707179127714473 11 Q9UHX1 1 +Prolonged neonatal jaundice 0.3613630304595506 0.5964984486458037 0.5508422899331031 1.0 0.871501035265968 20 Q8WWI5,P39210,Q15904,O15118,P56589 5 +Abnormality of globe size 0.3028980335868678 0.5955565942584472 0.5514714809567645 1.0 0.871501035265968 62 O43505,P52732,O75431,Q9BUK6,P53701,O75569,P29084,Q9UHX1,Q6NUK1,P21964,P17302,Q9NX14,Q96J42,Q12797,Q9H5K3 15 +Increased blood pressure 0.2959385769941506 0.5930808607312053 0.5531270384963198 1.0 0.871501035265968 77 P42892,P21912,P04062,P00403,P35610,Q10713,O75844,P21964,P03915,Q9BUB7,Q8TAA9,P17302,P36551,Q9Y4P3,P03886,P16435,Q9NQH7 17 +Gingival bleeding 0.4213389524000391 0.5925166377110067 0.5535046829141939 1.0 0.871501035265968 11 P04062,Q14108 2 +Femoral bowing 0.4357798047000136 0.592472605737054 0.5535341596035503 1.0 0.871501035265968 9 Q7RTS9,Q32P28 2 +Deformed sella turcica 0.5069681551043324 0.5922844645771382 0.5536601171621425 1.0 0.871501035265968 6 Q7RTS9,P08236 2 +Neonatal onset 0.3564790354377056 0.589806109910918 0.5553206459756765 1.0 0.8723138598158235 22 Q9H490,Q9P032,Q15904,P49748,Q8TB36,P40939,Q13546 7 +Bruising susceptibility 0.336434929006175 0.5872441806373977 0.5570397240475846 1.0 0.8734962407891967 29 P51798,P38435,Q9NWM8,Q8NCH0,P04062,Q14108,P49257 7 +Hypoplasia of the uterus 0.4275232297368793 0.5859827371447308 0.5578871156277876 1.0 0.8745257488219372 10 P53701 1 +Abnormal corpus striatum morphology 0.3617242046268229 0.5847064560598398 0.5587451122648421 1.0 0.8751152551720343 17 P00846,O75306,O43819,O95169,O95831 5 +Abnormal brainstem morphology 0.284966908874313 0.5805438312758261 0.5615479376496992 1.0 0.8782145676061032 91 O43505,Q96CU9,Q9NPL8,Q9Y375,O96000,Q10713,O60313,O75306,Q9Y6M9,O43819,Q9Y320,O43676,Q9NX14,P03886,Q86Y39,Q9H5K3 16 +Neck flexor weakness 0.6383202969888137 0.5775878893841018 0.5635423852406272 1.0 0.879601788393323 3 Q99720 1 +Myalgia 0.3020824878003556 0.5774716636908811 0.5636208753214309 1.0 0.879601788393323 47 P46020,Q13586,Q93063,Q8NBM4,Q9BUK6,O60313,P49748,P12235,Q8NCE2,O15460,P51530,P21964,P23786,Q9NZ08,P40939,Q14739 16 +Distal arthrogryposis 0.5335732499143169 0.5771438133952397 0.5638423091096647 1.0 0.8796477563297527 5 Q8NCH0,Q96A33 2 +Abnormality of nail color 0.5545632252880159 0.5675883554079444 0.5703145158962615 1.0 0.8848434000809227 4 P17302,P16615 2 +Leukonychia 0.5545632252880159 0.5675883554079444 0.5703145158962615 1.0 0.8848434000809227 4 P17302,P16615 2 +Red green dyschromatopsia 0.6354340745032212 0.5672827827181411 0.5705220726407438 1.0 0.8848434000809227 3 Q9H6K4 1 +Encephalocele 0.3799457757876398 0.566306930037573 0.5711851502551442 1.0 0.8848434000809227 15 Q10713,Q9H5K3 2 +Anarthria 0.5009690257725861 0.5658921289909522 0.5714671125352133 1.0 0.8848434000809227 6 Q8WVX9,P35637,Q99720 3 +Nocturia 0.6346634411656661 0.5645399859573866 0.5723866952945995 1.0 0.8848434000809227 3 P12235 1 +Multiple mitochondrial dna deletions 0.6346634411656661 0.5645399859573866 0.5723866952945995 1.0 0.8848434000809227 3 P12235 1 +Dry hair 0.5535806630744962 0.5637773564428475 0.5729056639446843 1.0 0.8853469653269962 4 P17302 1 +Flat face 0.3431817878568295 0.5631303539974564 0.5733461234825086 1.0 0.8857289068768895 26 P40855,O75381,Q9Y487,Q9BUB7,P08236,Q9NX62,Q9UM00 7 +Contractures involving the joints of the feet 0.3587464135546635 0.5567002280024668 0.5777322611220062 1.0 0.8901305141092112 18 P49902,P50402,Q9BTV4,O60313,Q8N2K0 5 +Convex nasal ridge 0.3559113843726499 0.5560601306814192 0.5781697491813582 1.0 0.8901305141092112 20 Q6NUK1,Q10469,O75844,P51530 4 +Pulmonary fibrosis 0.3541291536781809 0.55602168352871 0.5781960316609918 1.0 0.8901305141092112 21 P09601 1 +Malrotation of small bowel 0.5514510438979177 0.5555382510360062 0.5785265541285969 1.0 0.8901305141092112 4 Q8NCH0 1 +Hepatic fibrosis 0.32211279370432 0.554263964487214 0.5793982082646236 1.0 0.8904506513439877 32 P04062,Q10713,Q13510 3 +Intrauterine growth retardation 0.2653993228041561 0.5540977219718296 0.579511969076336 1.0 0.8904506513439877 201 Q96CU9,Q9Y487,O96000,Q15392,Q9BV10,Q9Y6M9,Q9BUB7,O95202,O43676,P40939,P03886,Q86Y39,Q5H8A4,Q9NPL8,Q9NXE4,P51572,O75844,P29084,Q6P4A7,Q9Y276,Q8TCJ2,Q16836,Q9NSD9,Q86SQ9,Q9Y375,O75208,O75845,P51798,P61619,Q9BT22,Q8WVQ1,Q9UHX1,P37268,Q6NUK1,Q9UBM7,P21912,P04062,O75306,P21964,Q9NX14,O75880 41 +Decreased proportion of cd4 positive helper t cells 0.4980745836466855 0.5532359316283738 0.5801018656179804 1.0 0.8905729758504616 6 Q13432 1 +Abnormality of chromosome segregation 0.5275521400958756 0.5524412128185536 0.5806461009447887 1.0 0.8905729758504616 5 Q14739,P17302 2 +Abnormality of the nasolabial region 0.4658025981526554 0.5514272144813548 0.5813408491420189 1.0 0.8905729758504616 7 Q8NCH0 1 +Prominent nasolabial fold 0.4658025981526554 0.5514272144813548 0.5813408491420189 1.0 0.8905729758504616 7 Q8NCH0 1 +Angiokeratoma 0.6294209702660418 0.5459811691726841 0.5850788814510475 1.0 0.8937071326367827 3 P04066,P06280 2 +Decreased muscle mass 0.3572053063903566 0.5456835483697994 0.5852834825788034 1.0 0.8937071326367827 18 Q8NCH0,Q8TAA9,Q9Y487 3 +Coxa vara 0.3864381707656305 0.5456053995741595 0.5853372119255751 1.0 0.8937071326367827 14 Q7RTS9,Q93063,Q9Y487,Q8WVQ1,O95831,O75718 6 +Abnormal hepatic iron concentration 0.6292159263649091 0.5452588972211972 0.5855754689770019 1.0 0.8937730842280555 3 Q658P3 1 +Abnormal pons morphology 0.350562883077527 0.544384528937002 0.586176889827648 1.0 0.8942238573822618 22 Q9H5K3 1 +Abnormality of the metacarpal bones 0.3079743645516062 0.5442621001831128 0.5862611234343769 1.0 0.8942238573822618 39 Q7RTS9,Q9UBM7,P51798,Q14739,P51812,O95202,Q9NX62,Q6NUK1,P16435,Q32P28 10 +Abnormalities of placenta or umbilical cord 0.3861446296261009 0.5437705401390631 0.5865993837822601 1.0 0.8944420554044312 14 O75844 1 +Gastrointestinal obstruction 0.385799298198985 0.54161279135831 0.5880852781154058 1.0 0.8955157010052474 14 P42892,Q01844,P21912 3 +Perimembranous ventricular septal defect 0.4636491977914694 0.5412834826016697 0.5883122035274879 1.0 0.8955636267650995 7 Q9UHX1 1 +Abnormality of the tarsal bones 0.3274422802481305 0.5396441605543622 0.5894424556978635 1.0 0.8965561357293478 30 Q7RTS9,O75844,Q9UHX1,Q969X5,P40939,Q14739 6 +Eeg with spike wave complexes 0.3945736483511418 0.5388228241646781 0.5900091131639711 1.0 0.8965561357293478 13 Q9NQZ5,O75503,Q14108 3 +Hyperactive deep tendon reflexes 0.4185201633345384 0.5369564261205595 0.5912977131070747 1.0 0.8974544330878442 10 Q9NR77,P21912 2 +Abnormal urine cytology 0.3080320156332828 0.536928366501075 0.5913170959171108 1.0 0.8974544330878442 38 P09601,P04062,P21912 3 +Autistic behavior 0.2625141813281216 0.5353712605494786 0.5923931591247666 1.0 0.897463020448986 187 Q96CU9,Q9H3H5,O95298,O96000,Q9Y6M9,Q15067,O43676,O75648,Q96N66,P03886,Q86Y39,Q5H8A4,Q7LGA3,O75503,Q9NPL8,Q5XKP0,Q9P0J0,Q9NZ01,Q9Y375,Q9UHX1,Q2TAA5,Q9UBM7,P21912,P51812,O75306,P21964,Q9Y4P3,Q9NX14,Q01105 29 +Abnormal intraocular pressure 0.4938223613216119 0.534739542574259 0.5928299740297276 1.0 0.897463020448986 6 Q8NCH0,Q15043,P04439 3 +Bilateral microphthalmos 0.4936999804340187 0.5342089668612139 0.5931969659904879 1.0 0.897463020448986 6 Q9UHX1 1 +Mandibular prognathia 0.3076709056555509 0.5332756488789816 0.5938427816818246 1.0 0.897463020448986 38 Q7RTS9,P52732,Q9NXE4,Q9BUK6,P51812,Q9UHX1,P17302,Q8NFG4,Q9NVI7,Q6NUK1,Q14696 11 +Abnormality of the gastric mucosa 0.3647222512299705 0.5322806364358872 0.5945316413570514 1.0 0.8981449097663703 16 Q15056,Q8N5K1,P04062,Q6PGP7,Q9Y4P3,Q14739,O76024,Q13546 8 +Craniofacial osteosclerosis 0.625427726702966 0.5319649108458834 0.5947502984619062 1.0 0.8981449097663703 3 Q15043 1 +Breech presentation 0.4615365677552123 0.531362183220603 0.5951678220195471 1.0 0.8981449097663703 7 Q969X5,O60313,Q9UBM7 3 +Azoospermia 0.4012045818464392 0.5261941705583197 0.598753303904781 1.0 0.9000617350057251 12 P04062,Q13423 2 +Eyelid myoclonus 0.4165087814166407 0.5260792971219213 0.5988331123784274 1.0 0.9000617350057251 10 Q13510 1 +Abnormality of primary teeth 0.3737387296998748 0.5259426862370901 0.5989280292519545 1.0 0.9000617350057251 15 P51798,O75844,P17302,Q8NC56,Q9UM00,P53634 6 +Abnormality of iron homeostasis 0.4914981155025408 0.5246801792185505 0.599805538302207 1.0 0.9009958570427428 6 Q658P3,Q9Y276 2 +Peroneal muscle atrophy 0.6229579138856167 0.523349590159983 0.600730997290956 1.0 0.9009958570427428 3 Q9NR77 1 +Short thorax 0.5429895386065664 0.5230962423680557 0.6009072803074442 1.0 0.9009958570427428 4 Q7RTS9 1 +Shallow orbits 0.4226028878249773 0.5229593499608233 0.6010025417251377 1.0 0.9009958570427428 9 O75431,Q8NC56,O75844 3 +Abnormal uvea morphology 0.2686491888624401 0.5224209145947568 0.6013772971507778 1.0 0.9009958570427428 104 O43505,P14174,Q13586,O95202,P40939,Q12797,Q5H8A4,Q86YV9,Q7LGA3,P40855,Q5XKP0,P52732,Q9NR77,O75340,P56589,P17302,Q9H5K3,Q9UHX1,P04439,O75381,Q9UBM7,P21912,P53701,Q10713,Q9Y4P3,Q9NX14,Q96J42 27 +Nausea and vomiting 0.2700235845889892 0.5222836670767378 0.6014728394129556 1.0 0.9009958570427428 146 Q96CU9,Q8NBM4,O96000,Q9Y6M9,P51571,O43676,O75648,P40939,Q13423,P03886,Q86Y39,Q9NPL8,P39210,P00403,P35610,P11117,Q16836,Q9Y375,P03915,P23786,Q9NZJ7,Q2TAA5,Q15165,P42892,P00846,Q9UBM7,P21912,O75306,P07602,P35637,Q9Y4P3,Q92804,Q9NX14 33 +Ulnar deviation of the wrist 0.519916834428323 0.5214506670607044 0.6020528634916678 1.0 0.9009958570427428 5 Q9BV10 1 +Recurrent respiratory infections 0.2715008979246902 0.5210579951920886 0.6023263712332383 1.0 0.9009958570427428 122 Q9UJW0,P14174,Q16637,O95298,Q9Y487,Q10469,Q9BV10,O95202,P10253,Q5H8A4,Q86YV9,Q13546,Q9NPL8,Q7RTS9,P09601,P29084,Q9H936,Q15056,P15586,P51798,Q03519,Q9NZJ7,O15460,P04062,Q9H0U3,Q13432,P07602,P08236,Q9Y4P3,Q13510,P53634,Q8N5M9 32 +Aplasia hypoplasia affecting the eye 0.2729148605788594 0.5200706316153109 0.6030143468198179 1.0 0.9009958570427428 99 O43505,Q13586,P07196,O95202,P61978,Q12797,Q86YV9,Q7LGA3,P52732,Q02978,O75569,P29084,P17302,Q9H5K3,Q15056,Q9UHX1,Q9NVI7,P37268,Q6NUK1,Q9UBM7,P21912,P53701,P21964,Q9Y4P3,Q9NX14,Q96J42 26 +Fatigable weakness of respiratory muscles 0.3726651357143672 0.5189925394234588 0.6037659438730207 1.0 0.9016658843915262 15 Q15165,Q92804 2 +Foot dorsiflexor weakness 0.3079301431442963 0.5173453713019299 0.6049150869968467 1.0 0.9016658843915262 35 Q9BQT8,P39210,Q99720,Q9NR77,O15269,P05023,O43819,Q8TB36,Q14739 9 +Increased muscle glycogen content 0.6209877413439275 0.5165072441240208 0.6055001807374172 1.0 0.9022444969557222 3 O75648 1 +Narrow mouth 0.2949670726416873 0.5136070490330353 0.6075267502437902 1.0 0.9025806292296636 67 P04062,Q8NCH0,Q9Y487,Q15392,O75844,P21964,Q9NX62,Q9NVI7,Q6NUK1,P16435,Q7LGA3 11 +Broad alveolar ridges 0.6199866790245222 0.513040972342886 0.6079226604492036 1.0 0.9025806292296636 3 Q9UBM7 1 +Aplasia hypoplasia involving the vertebral column 0.3714778453031057 0.5113178687683683 0.6091284948128672 1.0 0.9032449071950024 15 Q7RTS9,Q8TAA9,P08236,O95831,Q14739,Q15738 6 +Abnormal vitamin b12 level 0.4570786669265759 0.5105299870179626 0.609680211691602 1.0 0.9035151746938122 7 P41440 1 +Abnormality of the calcaneus 0.4196675034857076 0.5076393531245185 0.611706287062872 1.0 0.9053773923745052 9 Q7RTS9,Q14739 2 +Focal myoclonic seizure 0.4257796168019294 0.5068373686629877 0.612268934090908 1.0 0.9053773923745052 8 O75503,P21912 2 +Postaxial polydactyly 0.3490155159142518 0.5052540241654401 0.6133804300586512 1.0 0.9056799637723508 20 Q7Z4L5,Q14739,Q10713,Q96J42 4 +Abnormal femoral neck morphology 0.3061509858277348 0.5050781908429849 0.61350391864865 1.0 0.9056799637723508 36 Q7RTS9,O75431,Q9Y487,Q96A33,Q8WVQ1,Q10469,O75844,P29084,P51812,O75718 10 +Abnormal vertebral morphology 0.2687566355533895 0.5050298237238828 0.6135378890330374 1.0 0.9056799637723508 109 Q9BV10,Q8TAA9,O95202,O15228,Q14739,Q5H8A4,Q7Z2Z2,Q7RTS9,P17302,Q14108,Q9UM00,O75718,P15586,O75845,P51798,Q8NCH0,Q9UHX1,Q6NUK1,Q32P28,Q9UBM7,P04062,P10619,P51812,Q10713,P08236,Q9Y4P3,P16435 27 +Aplasia hypoplasia of the optic nerve 0.3472006559180999 0.5040697172992057 0.6142123862304762 1.0 0.9060707982360272 21 P37268,Q9UHX1,Q9H5K3 3 +Abnormal neural tube morphology 0.3021659731814274 0.5023524973082423 0.6154195873372093 1.0 0.9069966385265658 41 Q10713,P21964,Q9HC21,Q9UHX1 4 +Abnormality of facial soft tissue 0.270432743336729 0.500922340175352 0.6164257792835532 1.0 0.9081874343013636 124 Q9H3H5,Q9BUK6,P07196,Q10469,O15020,P40855,O60313,O75844,P12235,O75340,P56589,Q86VD7,Q9BQT8,Q12769,P51798,Q9UHX1,Q15043,O75381,Q9UBM7,P21912,P04062,P51812,O43819,P51530,Q9Y4P3,Q13510,P16435 27 +Skin erosion 0.4240376646272611 0.4980547771181499 0.6184454339512042 1.0 0.9103436249437244 8 O75844 1 +Type 1 muscle fiber atrophy 0.4850686095731858 0.4970500969178116 0.6191537241982594 1.0 0.9103436249437244 6 P50402,Q9BTV4 2 +Posteriorly rotated ears 0.26931432897776 0.4966829075015039 0.6194126776488909 1.0 0.9103436249437244 115 O43505,Q15392,Q10469,O95202,Q5H8A4,Q7LGA3,P40855,Q9NXE4,Q4J6C6,P56589,Q9UM00,Q9H5K3,Q9H490,Q8NCH0,Q9UHX1,P23786,Q6NUK1,P37268,P42892,O75381,Q9UBM7,P04062,Q10713,Q9Y4P3,Q96J42,P16435 26 +Limb girdle muscular dystrophy 0.4237465370273964 0.4965892942657614 0.6194787041847518 1.0 0.9103436249437244 8 O14979,P50402 2 +Megalocornea 0.3873074571491778 0.4953564916103967 0.6203485008639598 1.0 0.9105526053074868 13 O95202,Q5H8A4,Q9H5K3 3 +Cerebral cortical atrophy 0.2666897116337303 0.4949795836499467 0.6206145321639636 1.0 0.9105526053074868 103 Q96AA3,O75503,Q9H3H5,Q9NWS8,P00846,O96008,P00403,P04062,P51572,P51812,P29084,Q9BUB7,P03915,Q9UM00,O75648,P03886,Q7LGA3 17 +Bulbous nose 0.2994315163602229 0.4944529215506696 0.6209863469035612 1.0 0.9106021369661992 43 P42892,O75431,O75845,Q93063,Q9NXE4,Q96A33,P21964,P23786,P16435 9 +Agitation 0.3053365545191584 0.4919337115038866 0.6227662056449594 1.0 0.9117581569103578 35 P42892,O96008,P04062,P35610,Q92804,Q15165 6 +Pleural effusion 0.386455210236456 0.4902873720032574 0.6239305616147304 1.0 0.9122047968470628 13 P14174,Q8NBM4,Q14739,Q9NZ08 4 +Hyperconvex nail 0.4522307366533806 0.4880423300377461 0.6255198582899784 1.0 0.91320358422719 7 P42892,O95202 2 +Brisk reflexes 0.3409733654702501 0.4876932908310756 0.6257671046872453 1.0 0.91320358422719 23 O00483,Q99720,Q10713,Q8NI60,P35637,P20674 6 +Dysuria 0.4219228957036099 0.4874248879822971 0.6259572599158396 1.0 0.91320358422719 8 Q8N0X7,O76024,O00170 3 +Dolichocephaly 0.3116060292053718 0.4863947376616893 0.6266873208803059 1.0 0.91320358422719 33 P40855,Q7RTS9,O75381,Q10469,Q4J6C6,Q969X5,O95202,Q5H8A4 8 +Abnormality of facial musculature 0.2838875223287949 0.4863187499666246 0.6267411873729167 1.0 0.91320358422719 84 Q9H3H5,Q9BUK6,P07196,O15020,P40855,O60313,P12235,O75340,P56589,Q86VD7,Q9BQT8,P51798,Q9UHX1,Q15043,O75381,P04062,P51812,O43819,P51530,Q13510 20 +Narrow forehead 0.2933442004929912 0.486073063089007 0.6269153645927403 1.0 0.91320358422719 51 Q9H490,O75845,Q96A33,Q9UHX1,Q7LGA3 5 +Genu valgum 0.3081921621020421 0.485665082607555 0.6272046441647681 1.0 0.91320358422719 34 Q8N0X7,Q7RTS9,P51798,Q9NR77,P08236,Q9NX62,Q9Y4P3,Q7LGA3 8 +Diplopia 0.3457708177654392 0.4815027973316205 0.6301591920801106 1.0 0.9150286054771978 20 O14773,P04062,P53007,O15020,P18074,O00170,O15460 7 +Bronchitis 0.5088700584510542 0.4773384607766429 0.6331211277391953 1.0 0.9167409583813964 5 Q03519 1 +Spastic dysarthria 0.4137243389447034 0.4768301398656099 0.633483081650541 1.0 0.9167409583813964 9 Q8N0X7,Q8WVX9,Q9Y4W6 3 +Neoplasm of the skin 0.2987514256558938 0.4766158923106205 0.633635664599276 1.0 0.9167409583813964 42 P11802,P14324,P21912,P29084,P17302,Q8NFG4,P53634,Q06136,P16615 9 +Hypermetric saccades 0.6092125880531811 0.4761938836077372 0.6339362565710889 1.0 0.9168863407855836 3 O14773 1 +Proximal muscle weakness in upper limbs 0.375098620254345 0.475241129471338 0.6346151145383319 1.0 0.917578559423994 14 P07196,P36551,P50402,Q9BTV4 4 +Focal motor seizure 0.3412994669430715 0.4738863739744499 0.6355809364712914 1.0 0.9186338168175344 22 Q9H936,O75503,Q9H3H5,P21912,Q9UBB4,Q08209,Q8WVX9,Q01105 8 +Abnormality of the cerebral subcortex 0.2502855805592308 0.4694100492554764 0.6387765666740235 1.0 0.9221405886894692 370 P49902,Q96CU9,Q9H3H5,O95298,Q7KZN9,Q15392,Q9BV10,Q9BPX6,Q9BUB7,Q15067,O95202,Q9HC21,P51571,O75648,Q96N66,P03886,Q5H8A4,Q7LGA3,Q96AA3,O75503,P00403,P51572,Q96A33,O60313,P29084,P12235,Q9P0J0,O75340,Q9UM00,P17900,Q9NZ01,Q9H5K3,Q9UBX3,Q9H490,Q86XL3,Q9UHX1,P03915,O43681,Q8NI60,Q96PU5,Q15043,P23786,Q9NZJ7,Q2TAA5,Q9NVI7,P37268,Q6NUK1,Q9NWS8,P00846,Q9UBM7,P21912,P04062,P53701,P51812,Q10713,O75306,P07602,Q9Y320,Q9NX14,Q96J42,Q01105 61 +Decreased serum complement c3 0.5575719649561838 0.4667346329331459 0.6406897481660758 1.0 0.923057253066402 2 Q05655 1 +Dilated fourth ventricle 0.2986649752274266 0.4660703310041426 0.6411651591949745 1.0 0.923057253066402 41 Q9UBM7,Q9Y487,P15291,Q10713,P23786,Q96J42,Q9H5K3 7 +Abnormal urine alpha ketoglutarate concentration 0.4472471699817069 0.4651191916721909 0.6418461031057618 1.0 0.923057253066402 7 P21912 1 +Titubation 0.404878702463116 0.4638085562162004 0.642784912645554 1.0 0.923057253066402 10 Q5T8D3,Q99720 2 +Decreased specific antibody response to vaccination 0.526863705955929 0.4626885943173505 0.6435875948938419 1.0 0.923057253066402 4 Q9BV10 1 +Deep palmar crease 0.3816765893214222 0.4619872365425211 0.6440904733946549 1.0 0.923057253066402 13 O75431,Q9Y487,P61978,O00170,Q6NUK1 5 +Abnormal morphology of the abdominal musculature 0.3978766799424427 0.4617605137945988 0.6442530700787021 1.0 0.923057253066402 11 Q8NCH0,Q6NUK1 2 +Elbow flexion contracture 0.3307511132677104 0.4612818133658837 0.6445964312049806 1.0 0.923057253066402 26 P50402,Q969X5,P23786,P37268,Q7LGA3 5 +Epistaxis 0.3636410779313048 0.460988270142586 0.6448070207128052 1.0 0.923057253066402 15 Q13586,P38435,P04062,P49257,O15460 5 +Hypoplastic heart 0.5259628279045463 0.4593733511969798 0.6459660816488619 1.0 0.923057253066402 4 P17302 1 +Abnormality of female external genitalia 0.3019823579133137 0.4591990149125865 0.6460912579121478 1.0 0.923057253066402 35 P40855,O75381,Q9UBM7,P53701,Q15392,Q9NX14,Q6NUK1,P16435 8 +Dental crowding 0.3117652797428752 0.4586330263592577 0.6464977158842655 1.0 0.923057253066402 32 O75431,Q9UBM7,P51812,Q96A33,Q10469,O75844,P17302,Q92643,Q01105 9 +Lower limb muscle weakness 0.2970103841941003 0.4584208573152787 0.6466501097668422 1.0 0.923057253066402 42 P00846,Q9NR77,Q969X5,Q13510,P40939,O75298 6 +Skeletal dysplasia 0.2937995117886015 0.4580374140253894 0.6469255617729395 1.0 0.923057253066402 45 P40855,Q7RTS9,Q7Z2Z2,Q7Z4L5,O75381,P10619,P56589,P17302,P51648,Q14739 10 +Abnormal sella turcica morphology 0.4099776594101675 0.4575610780909173 0.6472678119272492 1.0 0.923057253066402 9 Q7RTS9,P08236 2 +Vocal cord paralysis 0.3424707282120078 0.4574602810383387 0.6473402447645888 1.0 0.923057253066402 20 P50402,P21912,Q9BTV4,Q9NR77,Q8TB36 5 +Abnormal corpus callosum morphology 0.2638359485438108 0.457096934739151 0.6476013734026775 1.0 0.923057253066402 281 P49902,Q9H3H5,Q15392,Q9BV10,Q9BUB7,O95202,Q9HC21,O75648,P51571,Q96N66,P03886,Q5H8A4,Q7LGA3,O75503,P00403,P51572,Q96A33,O60313,P29084,O75340,Q9NZ01,Q9H5K3,Q9UBX3,Q9H490,Q86XL3,Q9UHX1,P03915,Q96PU5,P23786,Q9NZJ7,Q9NVI7,P37268,Q6NUK1,P04062,P53701,Q10713,P07602,Q9Y320,Q9NX14,Q96J42,Q01105 41 +Increased serum iron 0.5245711007937895 0.4542648441572693 0.6496382162934013 1.0 0.9235219132616088 4 Q658P3 1 +Cervical spine instability 0.5538172715894751 0.4532043424060689 0.650401605876544 1.0 0.9235219132616088 2 Q99575 1 +Abnormality of the phalanges of the hallux 0.6023503722836969 0.4531846231357299 0.6504158040364931 1.0 0.9235219132616088 3 Q8WVQ1 1 +Abnormal arachnoid mater morphology 0.4087133906801769 0.4510873630100422 0.6519265851552203 1.0 0.9237218110687282 9 Q9NQH7,Q9UHX1 2 +Contractures of the joints of the upper limbs 0.2889241112524637 0.4509719583010746 0.6520097595818526 1.0 0.9237218110687282 70 P42892,P50402,Q99720,P07196,Q15392,O75844,Q9NR77,Q9BUB7,Q969X5,P17302,P35637,P23786,P37268,P16435,Q7LGA3 15 +Abnormal cerebral ventricle morphology 0.2631199514151088 0.4494192647276488 0.6531292367195691 1.0 0.9245940620185517 228 Q96CU9,Q9Y487,Q15392,Q9BV10,Q8TAA9,O95202,Q9HC21,Q5H8A4,P40855,Q9NPL8,P29084,O75340,Q9UM00,Q9H5K3,Q9H490,P51798,Q8NCH0,Q86XL3,Q9UHX1,P23786,Q9NZJ7,Q6NUK1,P00846,Q9UBM7,P04062,P53701,P51812,Q10713,P15291,P05023,O75306,P21964,O43819,P07602,Q9Y320,P08236,Q9NX14,Q96J42,P16435,Q01105 40 +Abnormal anterior eye segment morphology 0.2604481966944413 0.4487949557530759 0.653579577881676 1.0 0.9245940620185517 314 O43505,Q9H3H5,O14979,Q8NBM4,Q8WWV3,Q9BUB7,O95202,O15228,P08670,O75648,Q8N2K0,Q14739,P03886,Q06136,Q5H8A4,Q7LGA3,P40855,Q15800,P39210,P00403,O60313,O75844,Q9NR77,P29084,P12235,O75340,Q96HR9,P51648,Q9H5K3,O75845,Q9NWM8,Q8NCH0,Q9UHX1,P03915,Q03519,P23786,Q2TAA5,Q9NVI7,Q6NUK1,O75381,Q9UBM7,P21912,P04062,P53701,P10619,Q10713,P51812,Q53H12,P21964,P08236,Q9Y4P3,Q13510,Q9H6K4,Q9NX14,Q96J42,Q9Y287 56 +Upper limb asymmetry 0.5516270337922325 0.4453812692817383 0.6560442459798879 1.0 0.925776019427116 2 Q15555 1 +Muscle fibrillation 0.3426705672611356 0.4428558986650115 0.6578699681284004 1.0 0.9269856023659332 18 Q9NWS8,Q9BQT8,Q16637,Q13510,O95831 5 +Rimmed vacuoles 0.3605882297962414 0.4415501225593281 0.6588147836553757 1.0 0.9269856023659332 15 O14979,P50402,Q9BTV4,Q9Y5L0,P22626 5 +Motor regression 0.5503754693366589 0.4409343665668055 0.659260513056728 1.0 0.9269856023659332 2 P11766 1 +Aplasia hypoplasia affecting the fundus 0.3326789542093524 0.4392323295607684 0.6604932016671536 1.0 0.9270266489753262 24 P07196,Q9UHX1,P61978,Q9NVI7,P37268,Q9H5K3 6 +Increased skull ossification 0.5497496871088743 0.4387173655329376 0.6608663426168162 1.0 0.9271554139223062 2 P54802 1 +Axonal regeneration 0.5196820132197807 0.4364472732173887 0.6625122467017386 1.0 0.9285695387536234 4 Q8TB36 1 +Skeletal myopathy 0.4983069871334435 0.436045709993246 0.6628035654818913 1.0 0.9285695387536234 5 P21912 1 +Abnormal mitral valve physiology 0.2904434044007448 0.4345801195206455 0.6638672279614917 1.0 0.9294025347628232 46 O75431,Q8NBM4,P04062,P53701,P51812,O75844,O75306,O43819,P17302,Q9Y4P3,Q9NX14,P40939 12 +Abnormality of the plantar skin of foot 0.2970497217370909 0.4332881592753977 0.6648054391639273 1.0 0.9294025347628232 39 P42167,Q06136,P21912,P16615 4 +Exaggerated startle response 0.3990251275784076 0.4329150383335634 0.665076494435203 1.0 0.9294025347628232 10 Q9H0B6 1 +Subcapsular cataract 0.4108875193231819 0.4325771927399078 0.6653219615560193 1.0 0.9294025347628232 8 Q8N2K0,Q9H6K4 2 +Ectopic kidney 0.3589605661579446 0.4312283954698797 0.6663023090918136 1.0 0.9296580938668362 15 Q8TAA9,P51530,Q9UHX1 3 +Anonychia 0.384368428077768 0.4301306082982316 0.6671006358302585 1.0 0.9301034691317748 12 Q14739,P16615 2 +Feeding difficulties 0.2541403845852763 0.428878291442764 0.6680117991504491 1.0 0.9301034691317748 347 Q96CU9,Q9H3H5,Q99720,Q9Y487,O96000,Q15392,Q9BV10,Q10469,Q9Y6M9,Q9HC21,O43676,P51571,Q96N66,P40939,P03886,Q86Y39,Q5H8A4,O75648,Q7LGA3,Q96AA3,P40855,Q9NPL8,Q5XKP0,Q96A33,O60313,P46977,Q9UM00,O14678,Q8TCJ2,Q16836,Q9NZ01,Q9H5K3,Q7Z4L5,Q9Y375,Q9H490,Q96JX3,Q9UHX1,O43681,P23786,Q9NZJ7,Q2TAA5,Q9NVI7,P37268,Q6NUK1,Q9NWS8,O75381,Q9UBM7,Q9UGP8,P21912,P04062,P53701,P51812,Q10713,O75306,P21964,Q969X5,P07602,O43819,P35637,Q13510,Q9NX14,Q01105,O75880 63 +Arachnodactyly 0.30539372683903 0.4282941201117899 0.6684369992508588 1.0 0.9301034691317748 33 Q9H3H5,Q8NCH0,P21964,P16435,Q5H8A4 5 +Hepatic encephalopathy 0.5165936130244289 0.4252979101317413 0.6706195168493916 1.0 0.9306049420727176 4 Q9UJS0,A2RRP1,Q6NUQ1 3 +Arterial thrombosis 0.4384722123370758 0.425274288182697 0.6706367347717401 1.0 0.9306049420727176 7 O15460,Q8NBM4 2 +Diarrhea 0.2864148320905779 0.4241421007278346 0.6714621833085554 1.0 0.9311863571185838 71 P42892,Q7Z2Z2,P03886,P39210,P00403,P35610,Q96A33,Q15904,Q9BT22,P50416,P03915,P36551,Q13510,P40939,Q13423,Q16836,Q14566 17 +Adrenal insufficiency 0.31754504633728 0.4231860376124088 0.6721595329520285 1.0 0.9315341791691536 29 P40855,O96011,O75381,Q658P3,P56589,Q9H0R6,O00170,Q13423,P16435,P50542,O95470 11 +Urinary glycosaminoglycan excretion 0.4379582210377859 0.4229621172838113 0.6723229005919666 1.0 0.9315341791691536 7 P04066,P08236,P15586 3 +Abnormal skin morphology of the palm 0.2732071150686699 0.4197523166493013 0.6746664020715252 1.0 0.9318486889463636 92 P40855,Q9H3H5,O75431,Q9NXE4,O75381,P21912,Q8NCH0,Q9Y487,P51812,Q6NUK1,Q9UHX1,P56589,P42167,O95202,Q14739,Q06136,P16615 17 +Eeg with generalized slow activity 0.396480109371465 0.4195872808084549 0.674786981650815 1.0 0.9318486889463636 10 Q9H3H5 1 +Abnormality of metacarpal epiphyses 0.4935537471754972 0.4177734312671178 0.6761127780293021 1.0 0.9323583389657036 5 P16435,O95202 2 +Abnormality of long bone morphology 0.2561088461878358 0.417180562698796 0.6765463413480699 1.0 0.9323583389657036 172 O75431,Q13126,Q9Y487,Q10469,Q9BV10,O95202,O15228,O75648,Q14739,Q7LGA3,Q7Z2Z2,P40855,Q7RTS9,O75844,Q9NR77,P56589,P17302,O75718,Q9H936,Q7Z4L5,Q8N0X7,Q9H490,P51798,P38435,Q9UHX1,Q9UG56,P37268,Q32P28,O75381,Q9UBM7,P51812,P08236,Q9NX62,Q9Y4P3,Q96J42,P16435 36 +Acne 0.3655384973020004 0.4168720535591604 0.6767719957518812 1.0 0.9323583389657036 14 O00170,Q8NBM4,P21964,Q9NZ08 4 +Abnormal circulating dicarboxylic acid concentration 0.2910576058462546 0.4168557777957095 0.6767839012221586 1.0 0.9323583389657036 44 P41440,P40855,Q9NSD9,P28288,Q16134,O75845,Q9Y5L0,P55263,P37268,Q9UGP8,Q9UJS0,Q96DA6,P36551,P23786,O75648,O14678,Q14739 17 +Cerebellar vermis atrophy 0.3887383193128496 0.412101864531466 0.6802647621103288 1.0 0.9338471921244296 11 Q96S52,Q8WVX9,Q10713 3 +Constitutional symptom 0.2623661161419995 0.4108925084682388 0.6811513559262776 1.0 0.9338471921244296 251 P14174,P50402,Q9BUK6,Q99720,Q8NBM4,P07196,Q8TAA9,Q9BRK0,P40939,Q14739,Q13423,O75298,Q14566,Q8WWI5,Q15800,P35610,O60313,O75844,Q9NR77,O15269,Q4J6C6,Q3ZCQ8,P12235,P36551,Q14108,Q70HW3,Q12769,P51798,Q658P3,Q9UBB4,O43681,Q15043,P23786,Q9NZJ7,O15460,Q15165,P42892,P00846,Q9UGP8,P21912,P04062,P51812,Q53H12,P21964,P07602,P51530,P35637,Q9Y4P3,Q13510,Q9H6K4,Q92804,P50416,Q01844 53 +Abnormality of the peripheral nervous system 0.2614398348021995 0.4100402702930136 0.6817764069784866 1.0 0.9338471921244296 103 P42892,P41440,P39210,Q99720,P04062,Q9UBB4,Q10713,O60313,Q9NR77,O15269,P21964,Q15067,P07602,O43681,Q9NQZ5,Q8TB36,Q9NZJ7,Q8N2K0 18 +Overriding aorta 0.4005649763714922 0.4097306135808923 0.682003570452901 1.0 0.9338471921244296 9 Q9NX14,P53701,Q9Y4P3 3 +Abnormal metatarsal morphology 0.3288462042602205 0.4094595695158664 0.6822024314322848 1.0 0.9338471921244296 24 O43505,Q7RTS9,Q9UBM7,Q8WVQ1,Q15392,P08236,O95202,P16435,Q9H5K3 9 +Onion bulb formation 0.4001656310557175 0.4077209224108195 0.6834785751791261 1.0 0.934556499991273 9 Q8TB36,Q9NR77 2 +Abnormality of the autonomic nervous system 0.2872268183267608 0.4042956114507878 0.6859953522466258 1.0 0.9358798516704712 60 P42892,P41440,P04062,Q10713,P21964,Q15067,P07602,Q9NZJ7 8 +Facial hemangioma 0.4899922770746229 0.4042158877915981 0.6860539715286005 1.0 0.9358798516704712 5 P16435,Q10469 2 +Aplasia hypoplasia involving the skeletal musculature 0.3797352481365694 0.4041799366675337 0.686080406320627 1.0 0.9358798516704712 12 Q9Y487,Q9NR77,Q9H5K3 3 +Abnormal tongue physiology 0.3348867554146194 0.4026993360557033 0.6871694224173583 1.0 0.9368075850985824 20 Q9NWS8,Q16637,Q9BQT8,P10253,Q13510,O95831 6 +Abnormality of the fetal cardiovascular system 0.5861736450740302 0.400478740180015 0.6888039391259897 1.0 0.9373625331378926 3 P16435 1 +Aplasia hypoplasia of the hallux 0.3311390590338955 0.3976710694456944 0.6908726656265067 1.0 0.9381083553998164 22 O95202,Q5H8A4,Q9UHX1,Q7LGA3 4 +Abnormality of the fontanelles or cranial sutures 0.2616486922801628 0.3948936698584449 0.6929213618613823 1.0 0.9391571127638252 102 O75431,Q08J23,Q9Y487,P61978,O15228,Q14696,P40855,O75844,P29084,P56589,P17302,Q9UM00,P20674,O75718,O75845,P51798,Q8NCH0,Q9BT22,Q6NUK1,Q32P28,O75381,P51812,P21964,Q9NX62,Q8NC56,P16435 26 +Multicystic kidney dysplasia 0.3322000391834273 0.3933394307434357 0.6940687988453327 1.0 0.9391571127638252 21 P40855,O75381,Q9UBM7,Q10713,O60566,P56589,Q96J42 7 +B lymphocytopenia 0.4027011557620894 0.3926377481659636 0.6945870550622428 1.0 0.9391571127638252 8 Q13432 1 +Dermal translucency 0.3970913288429151 0.3923063624976148 0.6948318630903496 1.0 0.9391571127638252 9 O75844 1 +Hypoplasia of the brainstem 0.3161903867860277 0.3863433416787654 0.6992424054749509 1.0 0.9417891018395164 28 O43505,Q9Y320,Q10713,Q9H5K3 4 +Abnormal urinary color 0.4849492788214928 0.3852221630871192 0.7000728242831498 1.0 0.9417891018395164 5 P23786 1 +Open mouth 0.3127818210881306 0.382543602624068 0.7020581934361794 1.0 0.942799133154916 29 P04062,Q10713,Q86XL3,Q10469 4 +Glomerular deposits 0.5331664580725788 0.3816016390696064 0.702756868276948 1.0 0.9434608761924924 2 P57740 1 +Infantile onset 0.2547568444133569 0.3809775942239007 0.7032198742623847 1.0 0.9435295648229128 185 Q96CU9,Q9H3H5,O75431,Q93063,O95298,Q15904,O43292,Q9BRT2,O15020,Q9Y6M9,Q15067,O75648,Q9H9P8,Q9BUF5,P55795,Q8WVX9,P40939,Q13546,Q96AA3,Q9NPL8,Q5XKP0,P39210,Q12756,P55263,Q9NR77,Q9P0J0,P49366,Q6ZXV5,Q8TB36,Q9Y276,Q70HW3,Q96DP5,P20674,Q9Y4W6,Q9H5K3,Q9NSD9,P28288,Q9Y375,P49748,Q9Y6B6,Q92643,P23786,Q9NZJ7,Q2TAA5,O95831,Q9NVI7,Q5JPH6,Q10713,O75306,O95169,P07602,Q9Y320,Q96S52,Q5JRA6,Q53H12,P51970,O75746,P54098 58 +Tubulointerstitial nephritis 0.4834175529712468 0.3795018435385112 0.7043152355450937 1.0 0.944446125041738 5 P23786 1 +Impaired distal tactile sensation 0.5031007710393579 0.3776085316133841 0.7057214258570363 1.0 0.9452252479616896 4 P39210 1 +Metaphyseal striations 0.4826810773247404 0.3767596864296421 0.7063522023026751 1.0 0.9457936268120566 5 Q9UG56 1 +Abnormal cd4 cd8 ratio 0.4556532193864623 0.3749314120706767 0.7077114768523065 1.0 0.9466613141445018 6 Q13432 1 +Abnormal rectum morphology 0.3118789448201747 0.3748814709854391 0.7077486198491365 1.0 0.9466613141445018 29 P21912,P51812,P53701,Q8TAA9,Q9NX14 5 +Premature skin wrinkling 0.3320264736757392 0.3746300091505426 0.7079356517024351 1.0 0.9466613141445018 19 Q9Y487,O75844 2 +Myelomeningocele 0.5019817622302496 0.3737317161394192 0.7086039263696868 1.0 0.9466613141445018 4 O75845 1 +Heterotropia 0.2836379652197772 0.3733367359483852 0.7088978383533175 1.0 0.9466613141445018 52 Q9H3H5,P04062,P29084,Q9UHX1,O75340,Q9NVI7,P40939 7 +Joint swelling 0.3980688903360546 0.370353032097301 0.7111194645541581 1.0 0.9473371528899756 8 P14174,Q13510 2 +Impairment in personality functioning 0.2577681966888858 0.3694893250770294 0.711763028501091 1.0 0.9475009287019172 210 Q96CU9,Q9BUK6,Q7KZN9,Q8TAA9,O75648,Q96N66,P03886,Q7LGA3,P50897,O75503,Q13144,P00403,P12235,Q9P0J0,P36551,Q9Y276,Q9UM00,P17900,Q9NZ01,Q9Y4W6,Q8N0X7,Q9UBB4,P03915,O43681,Q9NZJ7,O15460,Q15165,P16615,Q6DKK2,O96008,P21912,P04062,P51812,O75306,P21964,P07602,P51530,P35637,Q9Y4P3,Q92804,Q9NWW5 41 +Delayed closure of the anterior fontanelle 0.3733336370140723 0.3687271186325087 0.7123311331428983 1.0 0.9479817752136974 12 P40855,O75381,Q9Y487 3 +Abnormal urine carboxylic acid level 0.3191564754123176 0.3679898056975428 0.7128808355523062 1.0 0.948291691410094 26 Q5XKP0,Q96JX3,Q53H12,O96000,Q9BUB7,Q3ZCQ8,Q9H6K4,Q9NVI7 8 +Tricuspid valve prolapse 0.575659871416901 0.3674708463413783 0.7132678342816177 1.0 0.948291691410094 3 P53701 1 +Distal muscle weakness 0.2832065738297998 0.3673045630590557 0.7133918507836303 1.0 0.948291691410094 67 Q9H3H5,Q9Y5L0,Q99720,Q96RL7,P07196,P40939,P41440,P39210,Q9NR77,O15269,O75340,Q8TB36,P36551,P22626,Q9Y4W6,Q9BQT8,P18887,O95831,P00846,Q96BR5,P35637,P54098 22 +Delayed puberty 0.2833196822657456 0.3646390281361775 0.7153808775806316 1.0 0.9490084484871032 54 Q15800,P04062,O75844,Q14108,Q9NVI7 5 +Broad hallux phalanx 0.527847309136408 0.3639824734185755 0.7158710972070832 1.0 0.9493838979458336 2 P49711 1 +Emotional lability 0.2834489975159522 0.3611663115796321 0.7179751243031673 1.0 0.9510731481807208 57 Q96CU9,O00483,Q8N0X7,Q7KZN9,O75306,P49770,Q9P0J0,O43681,P07602,P35637,Q9Y276,Q9NZJ7,O00170,Q96DP5,Q92804,Q15165,P54098,Q13144 18 +Aortic regurgitation 0.3182504399457209 0.3607864879151117 0.7182590645353137 1.0 0.9511742871967652 26 Q96PU5,O75844,Q9UHX1 3 +Abnormal aldolase level 0.4977091104549047 0.3590447982439401 0.719561576420739 1.0 0.9526238495116516 4 Q9H5K3 1 +Poor motor coordination 0.3785010306471156 0.3575414591551136 0.7206864945686156 1.0 0.9534540195886524 11 Q10713 1 +Constipation 0.2663642939464535 0.3571258090959531 0.7209976238993996 1.0 0.9534540195886524 95 P42892,Q8N0X7,P21912,P04062,Q8NCH0,P00403,P37268,Q13423,P21964,P03915,P12235,P03886,P16435,Q7LGA3 14 +Hypoplasia of the frontal lobes 0.3952344733963908 0.3568376334111179 0.721213361095159 1.0 0.9534540195886524 8 Q86XL3 1 +Calvarial hyperostosis 0.4772777182634174 0.3568086932113835 0.7212350278464128 1.0 0.9534540195886524 5 Q15043 1 +Aplasia hypoplasia of the scapulae 0.4959951734761164 0.3532057379720412 0.7239342064925625 1.0 0.9534540195886524 4 Q7RTS9 1 +Sloping forehead 0.284990337527821 0.3528577006071994 0.724195123607545 1.0 0.9535035257859374 44 Q9H936,P52732,Q9NXE4,O75845,Q08J23,Q86XL3,Q9HC21,P23786,Q96J42 9 +Lambdoidal craniosynostosis 0.5708105542098465 0.3526004626844911 0.7243879906723807 1.0 0.9535035257859374 3 P16435 1 +Abnormal blood sodium concentration 0.3830525706271206 0.3504378825134534 0.72601010046761 1.0 0.9542450640516836 10 Q13423,Q9BV10 2 +Fragile nails 0.3771127060436327 0.3502390414400348 0.7261593091690266 1.0 0.9542450640516836 11 Q9Y487,P29084 2 +Delayed fine motor development 0.393562706826587 0.3489106485367802 0.7271563906012211 1.0 0.9546817773475468 8 P16435 1 +Abnormal hair laboratory examination 0.3934449707726448 0.3483536514754763 0.7275746059180657 1.0 0.9546817773475468 8 Q9Y276,P18074,P29084 3 +Hypoplasia of the iris 0.4489406630579554 0.3482144855898352 0.7276791098183388 1.0 0.9546817773475468 6 O95202,Q7LGA3 2 +Abnormal serum iron concentration 0.4748952378281603 0.3481077972109166 0.7277592287995973 1.0 0.9546817773475468 5 Q658P3 1 +Esophageal varix 0.4940145942903677 0.3464964371714471 0.728969661306337 1.0 0.955144120133153 4 P04062 1 +Tibial bowing 0.493837593365244 0.3458988489752311 0.7294187337018045 1.0 0.9554593018358114 4 Q7RTS9 1 +Enlarged posterior fossa 0.2807697918257031 0.341087647639716 0.7330376000079402 1.0 0.9585554461291044 52 Q9NPL8,Q9H490,Q9UBM7,O95298,Q9Y487,P15291,Q10713,P23786,Q96J42,Q9H5K3 10 +Urinary retention 0.4468887925189462 0.3401444752622917 0.7337477299900712 1.0 0.9592102992338106 6 Q8TAA9,Q93063 2 +Congenital nystagmus 0.3275235082148562 0.3383773176602757 0.7350788649551041 1.0 0.960024758554324 18 P00846,Q7LGA3 2 +Abnormality of toe 0.2509711760158016 0.3364866700503097 0.7365039019308721 1.0 0.9606083103625268 176 P49902,O75431,Q99720,Q9BV10,O95202,O75648,Q14739,Q5H8A4,Q7LGA3,P39210,Q96A33,O75844,Q9NR77,Q8TB36,Q9UM00,Q7Z4L5,Q8N0X7,O75845,P13073,Q9UHX1,Q96PU5,P23786,P37268,Q9UBM7,P04062,P51812,Q10713,P21964,Q9NX62,Q9Y4P3,Q13510,Q96J42 32 +Ankyloblepharon 0.4704942794863145 0.332195190249481 0.7397418753700074 1.0 0.9626518809842016 5 O75569 1 +Abnormal odontoid tissue morphology 0.2819221104405702 0.3311641312654301 0.7405205120950855 1.0 0.9626963213365296 45 Q9UBM7,P53701,P29084,P21964,P17302,P51648,Q9Y4P3,Q5JRA6,Q9NX14 9 +Hypoplastic aortic arch 0.4893196774131841 0.3307589835819094 0.7408265449656488 1.0 0.9626963213365296 4 Q9UHX1 1 +Esodeviation 0.2877067260188748 0.3293605713827506 0.7418831661931486 1.0 0.9630016443319978 37 Q9NVI7,O75340,P04062,Q9UHX1 4 +Abnormality of the scrotum 0.2795419862648398 0.3292646183904737 0.7419556848353195 1.0 0.9630016443319978 47 P46977,Q9BV10,Q6NUK1,Q9UM00,O75648,Q8TCJ2,P16435,Q7LGA3 8 +Cyanosis 0.3260568795483491 0.3284429858487391 0.7425767459412107 1.0 0.963175794912976 18 Q00325,P51812,Q969Y2,O75844,P53007,P17302 6 +Heparan sulfate excretion in urine 0.4878444350316978 0.3258633270583009 0.7445277632713281 1.0 0.9642643030897834 4 P08236 1 +Enamel hypoplasia 0.3502512005043837 0.3258226874364818 0.7445585125123644 1.0 0.9642643030897834 14 P51648,P29084 2 +Abnormal insulin level 0.3177339637526225 0.3243964106589707 0.7456379368290316 1.0 0.9649520385867392 24 P31751,O75431,O75844,P00367,Q96HR9,P40939,Q16836 7 +Gray matter heterotopia 0.3133532668761848 0.3221035827557974 0.7473742241655037 1.0 0.9649520385867392 26 O43505,Q9UBM7,Q86XL3,Q96PU5,Q2TAA5,P61978,Q6NUK1,Q9H5K3 8 +Conspicuously happy disposition 0.5147058823529281 0.3220190055108294 0.7474382964676616 1.0 0.9649520385867392 2 P55795 1 +Abnormal clavicle morphology 0.3250504033554599 0.3216464318921105 0.7477205639513791 1.0 0.9649520385867392 18 Q14739,O75844 2 +Abnormal circulating sulfur amino acid concentration 0.3826234177223928 0.3212309777063584 0.7480353583005106 1.0 0.9649520385867392 9 P41440,O14678,P55263 3 +Left ventricular noncompaction cardiomyopathy 0.514392991239037 0.3210480130455228 0.7481740060280977 1.0 0.9649520385867392 2 Q15233 1 +Abnormal umbilicus morphology 0.2801595635492247 0.3209497222514121 0.748248492601197 1.0 0.9649520385867392 61 Q8NBU5,Q9NWM8,Q9Y487,Q8NCH0,O75844,P29084,Q6NUK1,Q9BUB7,P21964,P08236,P17302,Q9Y4P3,Q14739 13 +Abnormal circulating porphyrin concentration 0.48586285848477 0.319325251937793 0.7494798859659988 1.0 0.9655251025584796 4 P22830 1 +Irritability 0.274822583267597 0.3189295933922785 0.749779902943895 1.0 0.9655251025584796 78 P50897,P00846,P21912,Q8NBM4,P07602,Q9HC21,Q9NZJ7,Q13510,P37268 9 +Abnormality of blood circulation 0.2790367344333591 0.3188653713203513 0.7498286043448235 1.0 0.9655251025584796 68 Q9H3H5,P38435,Q8NBM4,P21912,Q9Y487,P04062,O75844,Q9UHX1,P21964,P23786,Q14739 11 +Craniosynostosis 0.2855254088365219 0.3183239674253625 0.7502392057497205 1.0 0.9655251025584796 39 Q8NCH0,P29084,P21964,Q9NX62,Q9UM00,Q6NUK1,P16435 7 +Hemivertebrae 0.3762494748409167 0.3162395356065378 0.7518207012820122 1.0 0.9664154853205424 10 P16435,Q9UHX1 2 +Abnormal proportion of cd4 positive t cells 0.3865707082412235 0.3161325367461234 0.7519019114147067 1.0 0.9664154853205424 8 Q13432 1 +Motor polyneuropathy 0.3563303670636771 0.3161162481820531 0.7519142743709588 1.0 0.9664154853205424 13 Q92734,P54886,P07196,O43819,P53007,P36551,Q15041 7 +Septo optic dysplasia 0.5125156445556864 0.3152502868084593 0.752571627236827 1.0 0.966989118339636 2 Q8WWQ0 1 +Myositis 0.3756611511426196 0.3133111359235612 0.7540442905106477 1.0 0.9683382676905234 10 Q9NZ08,Q8NBM4 2 +Abnormal upper motor neuron morphology 0.3699522046546417 0.3129777252721186 0.754297585264025 1.0 0.968392136643251 11 Q99720 1 +Developmental cataract 0.2792004103869474 0.3109536129011601 0.7558358861292698 1.0 0.9700952465670348 58 Q9H3H5,Q15800,P21912,P00403,P03886 5 +Extra axial cerebrospinal fluid accumulation 0.5109511889862197 0.3104560470765422 0.7562141786463215 1.0 0.9702822996781076 2 Q03252 1 +Scapular winging 0.3175374215876801 0.3102048993849244 0.7564051450131384 1.0 0.9702822996781076 23 Q9H3H5,P50402,Q9BTV4,Q9Y487,P07196,O60313,O75340,P54098 8 +Chronic diarrhea 0.3214111544076319 0.3064509594318488 0.7592613134023987 1.0 0.9715188892695062 17 Q96A33,Q13510 2 +Abnormality of the pubic bone 0.3793005278827841 0.305281521385341 0.7601517484203031 1.0 0.9719669316597686 9 Q7RTS9,Q5H8A4 2 +Hypercholesterolemia 0.353411323841585 0.2998676771074273 0.7642780903030497 1.0 0.9755586056754706 13 Q8N511,O75431 2 +Reduced factor xi activity 0.5529095467061191 0.2997723514979606 0.7643508062799955 1.0 0.9755586056754706 3 Q9BV10 1 +Increased circulating antibody level 0.3456692059070503 0.2991827594138138 0.7648006031793173 1.0 0.9758608643184716 14 P04062 1 +Aganglionic megacolon 0.3207912173629834 0.2971276264333106 0.7663690734336193 1.0 0.97677415701609 19 Q10713,P21964 2 +Abnormality of the upper arm 0.3186413666730077 0.2960149355157786 0.767218675386045 1.0 0.977313308484531 21 Q7RTS9,P50402,Q9BV10,O15228,P16435 5 +Ovarian cyst 0.3286127853083771 0.2956103097502368 0.7675276993080828 1.0 0.9774352190743846 16 P31751,P16435,P21912 3 +Sensory axonal neuropathy 0.3196476985382729 0.2948049982286606 0.7681428480092438 1.0 0.9777500011649468 17 Q15067,Q9H0B6 2 +Patellar dislocation 0.3195787586594526 0.2947280160760774 0.7682016595796177 1.0 0.9777500011649468 20 Q8WVQ1,P21964,Q6ZXV5,Q9NX62,Q96PU5,Q9Y4P3 6 +Decreased corneal reflex 0.5496195966366222 0.2904338697806422 0.771484335467699 1.0 0.9799844561396112 3 Q2TAA5 1 +Vascular neoplasm 0.2826412648190102 0.2900007673559879 0.7718156505526181 1.0 0.9799844561396112 39 P21912,P10619,Q10469,Q9UHX1,O95202,P16435,Q5H8A4,Q7LGA3 8 +Dystonia 0.2486107098770696 0.2878488763499277 0.7734624220245896 1.0 0.9811751987033968 176 Q96CU9,Q99720,Q7KZN9,Q15067,O14949,Q96N66,P03886,P39210,P51572,Q9P0J0,O15118,Q86VD7,P17900,Q9NZ01,Q96JX3,P03915,O43681,Q15043,Q9NZJ7,P00846,Q6DKK2,P04062,Q9NQZ5,P07602,Q01105 25 +Poor wound healing 0.4330053285119877 0.2868175571268959 0.7742520188587871 1.0 0.9816333011651804 6 P04062 1 +Aplasia hypoplasia affecting bones of the axial skeleton 0.2566372024254912 0.2848303320620303 0.7757741327071179 1.0 0.9827473254254948 247 Q9H3H5,O75431,Q15392,Q9BV10,Q9BUB7,Q8TAA9,O95202,Q9HC21,O15228,O75648,P51571,Q14739,Q5H8A4,Q7LGA3,Q96AA3,P40855,Q7RTS9,O75844,P29084,Q9UM00,O14678,Q7Z4L5,O75845,Q8NCH0,Q9BT22,Q86XL3,Q9UHX1,Q96PU5,Q9NVI7,P37268,Q6NUK1,O75381,Q9UBM7,P04062,P53701,P21964,Q969X5,P51530,P08236,Q9NX62,Q9Y4P3,Q9NX14,Q96J42,P16435 44 +Gingival overgrowth 0.3010599482952927 0.284266948276254 0.7762058132137633 1.0 0.9830223980501556 29 Q15056,Q9Y5U9,Q9UBM7,O75845,Q10469,Q96S52,P08236,Q9UM00,Q9Y4P3,Q14739 10 +Aplasia hypoplasia involving bones of the feet 0.2755061642216124 0.2819011657397256 0.7780192956426635 1.0 0.9847746996228408 70 Q7RTS9,Q96A33,P13073,Q9UHX1,Q9NX62,Q13510,Q5H8A4,Q7LGA3 8 +Cranial asymmetry 0.4314589453997087 0.2810228544619131 0.7786928705748417 1.0 0.9852833195252882 6 P40855 1 +Microvesicular hepatic steatosis 0.3635377266072535 0.2802118182232549 0.7793150001022082 1.0 0.985325974191037 11 Q96DA6,P39210,Q9Y276,O75648 4 +Hypomimic face 0.3560784519996623 0.2758697703265209 0.7826480930408306 1.0 0.988721687982654 12 P04062,P12235 2 +Abnormality iris morphology 0.2687371239135829 0.2754215634201774 0.7829923792597269 1.0 0.9888839806416948 84 O43505,Q7LGA3,P40855,O75381,Q9UBM7,P21912,P53701,Q10713,Q9NR77,Q9UHX1,O75340,P56589,O95202,Q9Y4P3,Q9NX14,Q96J42,Q5H8A4,Q9H5K3 18 +Exodeviation 0.3109598158686762 0.2736284624633034 0.7843701586026648 1.0 0.9900237886219074 24 Q9H3H5,Q9UHX1 2 +Death in childhood 0.3123792095715128 0.2723718841054323 0.7853360889778278 1.0 0.9903967894605014 23 Q9NPL8,O75431,Q8TCJ2,P20674,Q96IX5 5 +Diffuse cerebellar atrophy 0.4028810196680956 0.2719518273566594 0.7856590599407043 1.0 0.9903967894605014 7 P18074,P29084,Q12756 3 +Irregular hyperpigmentation 0.2753220929074327 0.2705568810556499 0.7867318631350269 1.0 0.9909184198123044 67 P21912,O75844,Q14739,Q06136,P16615 5 +Short long bone 0.2850698652282318 0.2687199397187787 0.7881452063217966 1.0 0.9915654407925514 34 Q7Z4L5,Q7RTS9,Q9BV10,Q9UHX1 4 +Uncombable hair 0.4965581977471728 0.2679812883511953 0.7887137218615421 1.0 0.9920083100657662 2 Q6PGP7 1 +Progressive inability to walk 0.3164099081586703 0.2675152677213254 0.789072460455245 1.0 0.9921309173125552 19 P00846,P21912 2 +Abnormal cranial nerve morphology 0.2743328146579247 0.2672921131179144 0.7892442587525674 1.0 0.9921309173125552 70 P40855,Q9H3H5,O75381,P51798,P21912,P51812,P07196,P12235,Q9UHX1,O75340,P56589,O43819,Q15043,P51530,Q13510 15 +Abnormality of the ribs 0.2749486750699325 0.2660107885309375 0.7902309002422552 1.0 0.992191987965436 67 Q7Z4L5,Q7RTS9,O75431,P51798,Q9UBM7,O75844,Q9BV10,Q9UHX1,Q8TAA9,O95202,Q9UM00,Q32P28,Q14739,P16435,Q5H8A4,O75718 16 +Aspiration pneumonia 0.311478673664406 0.26582297653475 0.7903755469388567 1.0 0.992191987965436 23 P04062,Q13510 2 +Metaphyseal widening 0.3158286204207491 0.263614974744884 0.7920766184096601 1.0 0.9925847964151042 19 Q7Z2Z2,Q7RTS9,Q93063,Q8WVQ1,P17302,Q14739 6 +Deviation of the 2nd finger 0.4683266129337708 0.2634485878146562 0.7922048451527797 1.0 0.9925847964151042 4 Q9H6K4 1 +Right ventricular hypertrophy 0.5395931142410043 0.2627213017731077 0.7927653969426065 1.0 0.9927442057368197 3 Q969Y2,Q15233 2 +Impaired glucose tolerance 0.5392497693746832 0.2617926737756911 0.7934812876237558 1.0 0.9928424555814956 3 O00170 1 +Decreased fertility in females 0.4249539233327949 0.2569854298622692 0.7971900207320723 1.0 0.9947284673278456 6 Q96RD7 1 +Abnormality of refraction 0.2548433187292704 0.2564140839943445 0.7976311138484853 1.0 0.9947593259808816 150 P49902,Q9H3H5,Q9Y487,Q15904,O43292,Q15067,O75648,P40939,Q5H8A4,Q7LGA3,Q7Z2Z2,Q96A33,P29084,P12235,P51648,Q9H5K3,Q9H490,Q9NWM8,Q8NCH0,Q9UHX1,Q9NVI7,Q6NUK1,O15460,P21912,Q53H12,O43819,Q9Y4P3,Q9NX14 28 +Reduced antithrombin iii activity 0.4245545710455258 0.2555279772120213 0.798315337949949 1.0 0.9948799742055892 6 Q9H3H5 1 +Diminished movement 0.3081059955024889 0.2525272673678493 0.8006335405761829 1.0 0.9948799742055892 24 P04062,Q9H3H5,Q2TAA5,P12235 4 +Abnormal sternum morphology 0.2535085031114725 0.2516331737796187 0.8013246145365645 1.0 0.9948799742055892 110 O75431,P50402,Q9Y487,Q10469,O95202,Q14739,Q7LGA3,Q7RTS9,Q96A33,Q7Z4L5,Q9H490,Q8NCH0,Q9UHX1,Q9NVI7,P21912,P04062,P51812,P08236,Q9Y4P3,Q13510 20 +Abnormality of the calf 0.2740365418732335 0.2496025112106363 0.8028947563829636 1.0 0.9963226515064276 60 Q7Z2Z2,Q7RTS9,Q8N0X7,O75431,Q13126,P51798,Q9BV10,Q9NR77,P08236,Q9NX62,Q9Y4P3,Q32P28,P16435,O75718,Q7LGA3 15 +Cardiac diverticulum 0.4630557294928048 0.2473871627090636 0.8046086081652111 1.0 0.9977582253350464 4 P60866,Q16658,P43246 3 +Aplasia cutis congenita of scalp 0.3956467912349619 0.2427459228234609 0.8082022299433089 1.0 1.0 7 Q5H8A4 1 +Patchy palmoplantar hyperkeratosis 0.5311736561505631 0.2403488702754787 0.8100598121014606 1.0 1.0 3 Q06136 1 +Neonatal hypoglycemia 0.3554632247520378 0.2398734712545442 0.8104283473815546 1.0 1.0 11 P31751,Q96DA6,P40939,Q16836 4 +Accessory spleen 0.3691967682441069 0.2375991041389324 0.8121920454136957 1.0 1.0 8 Q96J42,O95202 2 +Biparietal narrowing 0.3480540702997801 0.2342535203278899 0.814788167445434 1.0 1.0 12 Q10713,O75845 2 +Aphthous ulcer 0.3682360080864252 0.2333895739178278 0.8154589084656203 1.0 1.0 8 Q8NBM4 1 +Abnormal b cell morphology 0.3535006376302358 0.2302325360368027 0.8179110807547518 1.0 1.0 11 Q13432 1 +Weight loss 0.2698359952961652 0.2281583084641783 0.8195231716625926 1.0 1.0 74 P42892,Q8NBM4,Q99720,P21912,P04062,O75844,P07602,Q9NZJ7,Q06136 9 +Abnormality of bladder morphology 0.3580696457663105 0.2281269000651148 0.8195475881707319 1.0 1.0 10 Q9NWM8,P16435,Q9Y4P3 3 +Abnormality of abdominal situs 0.4394226510617572 0.2263635316823618 0.8209186893044094 1.0 1.0 5 Q5H8A4 1 +Rib segmentation abnormalities 0.4394226510617572 0.2263635316823618 0.8209186893044094 1.0 1.0 5 Q5H8A4 1 +Hypoplastic pubic rami 0.4394226510617572 0.2263635316823618 0.8209186893044094 1.0 1.0 5 Q5H8A4 1 +Fatigable weakness of bulbar muscles 0.3173145589038413 0.2257111451584508 0.8214260891818927 1.0 1.0 16 Q15165,Q92804 2 +Hypoplasia of the odontoid process 0.4159033684722909 0.2244944691680935 0.8223725700650972 1.0 1.0 6 Q7RTS9,P08236 2 +Elevated tissue non specific alkaline phosphatase 0.4806007509386589 0.2244897979714305 0.8223762043979941 1.0 1.0 2 P55072 1 +Proptosis 0.2709610251017809 0.2229365557456464 0.8235848848922114 1.0 1.0 55 O75431,Q9UBM7,Q8WVQ1,O75844,O95202,Q15043,Q9NX62,Q8NC56,Q32P28,Q6NUK1,P16435,Q5H8A4,O75718 13 +Dermatological manifestations of systemic disorders 0.2686233551598314 0.2179847066261176 0.8274410272581223 1.0 1.0 75 Q9H3H5,Q00325,Q9Y5L0,Q15904,P53007,O75648,Q14739,P40855,Q8WWI5,P39210,Q16134,Q969Y2,O75844,O15118,P56589,P17302,P36551,P50542,P28288,Q9Y5U9,P00374,P49748,O96011,O75381,Q9UJS0,P51812 26 +Upper limb muscle weakness 0.2997733886519872 0.2174217112628435 0.8278797127265869 1.0 1.0 26 Q8N0X7,P00846,P50402,P07196,Q969X5,P36551 6 +Wide nasal ridge 0.4517796992621242 0.2142417006035884 0.8303585785634848 1.0 1.0 4 P61978 1 +Thoracolumbar kyphosis 0.3883869469904872 0.2142161536331563 0.8303784996813091 1.0 1.0 7 P04062,Q10469 2 +Gastroparesis 0.3502075699775315 0.214207578727942 0.8303851862793103 1.0 1.0 11 Q10469,Q9BUB7,P12235,P61978,P54098 5 +Hyperglycemia 0.4126736510712342 0.2131814833788537 0.831185410435322 1.0 1.0 6 O75844 1 +Abnormality of cranial sutures 0.2651813481361412 0.2131012047142639 0.831248025000412 1.0 1.0 82 O75431,Q08J23,Q9Y487,P61978,P40855,O75844,P29084,Q9UM00,O75718,O75845,P51798,Q8NCH0,Q6NUK1,Q32P28,O75381,P51812,P21964,Q9NX62,Q8NC56,P16435 20 +Abnormal venous morphology 0.2990628144617144 0.2120643686139176 0.8320568172038489 1.0 1.0 26 P04062,Q9Y487,P21964 3 +Pelvic kidney 0.3629789725963154 0.2106246136058736 0.8331802042652492 1.0 1.0 8 Q9Y4P3,Q9UHX1 2 +Absent toe 0.3006171024958986 0.2098396664970925 0.8337928128357222 1.0 1.0 25 O95202,Q5H8A4,Q9UHX1,Q7LGA3 4 +Steppage gait 0.3034640076311692 0.2083457127302589 0.8349590410843808 1.0 1.0 23 P07196,P05023,Q9NR77,O15269,O43819,Q8TB36 6 +Anal atresia 0.2984280049492406 0.2072894307102943 0.8357838279632244 1.0 1.0 26 Q9NX14,P53701,P21964 3 +Ptosis 0.2520704197931369 0.2049524956949907 0.837609240030831 1.0 1.0 230 Q96CU9,Q9H3H5,P50402,Q7KZN9,O96000,Q9BPX6,Q9Y6M9,O95202,O43676,O75648,P03886,Q86Y39,Q5H8A4,O95470,Q7LGA3,P40855,Q9NPL8,Q96A33,O60313,P12235,Q9P0J0,O75340,Q5T8D3,Q9UM00,Q9Y375,O75845,Q86XL3,Q9UHX1,Q9NZJ7,O15460,O75381,Q9UBM7,P04062,Q10713,O75306,P21964,O43819,P07602,P51530,Q9NX14 40 +Decreased circulating iga level 0.3857677790557541 0.2041248033393022 0.8382559721184373 1.0 1.0 7 P42345,Q15904,P00813,Q969N2 4 +Vertebral clefting 0.3613262701656564 0.2035640925932105 0.8386941555094793 1.0 1.0 8 O75845 1 +Axonal degeneration regeneration 0.4315690573128893 0.201613264168239 0.8402190748613863 1.0 1.0 5 O60333,Q8TB36,P51149,O95140 4 +Dysphagia 0.2532545507505202 0.2011218326573045 0.8406033107955393 1.0 1.0 136 P00846,P21912,P04062,Q99720,Q14739,Q9NR77,Q9UHX1,P03915,P07602,Q15067,P12235,Q14108,O15118,Q9NZJ7,Q13510,P03886,Q01105 17 +Abnormal fallopian tube morphology 0.3565014224502274 0.2003065069859154 0.8412408738378288 1.0 1.0 9 P53701 1 +Increased mean corpuscular hemoglobin concentration 0.4467190872672095 0.1999248698100744 0.8415393397869273 1.0 1.0 4 P29084 1 +Abnormal mean corpuscular hemoglobin concentration 0.4467190872672095 0.1999248698100744 0.8415393397869273 1.0 1.0 4 P29084 1 +Numerous pigmented freckles 0.4467190872672095 0.1999248698100744 0.8415393397869273 1.0 1.0 4 P29084 1 +Defective dna repair after ultraviolet radiation damage 0.4467190872672095 0.1999248698100744 0.8415393397869273 1.0 1.0 4 P29084 1 +Low set nipples 0.4467190872672095 0.1999248698100744 0.8415393397869273 1.0 1.0 4 P29084 1 +Abnormality of dna repair 0.4467190872672095 0.1999248698100744 0.8415393397869273 1.0 1.0 4 P29084 1 +Tiger tail banding 0.4467190872672095 0.1999248698100744 0.8415393397869273 1.0 1.0 4 P29084 1 +Concave nail 0.4467190872672095 0.1999248698100744 0.8415393397869273 1.0 1.0 4 P29084 1 +Duplication of hand bones 0.2690729874962454 0.1994028534482571 0.8419476285756438 1.0 1.0 56 Q7Z4L5,O75845,Q10713,Q9UHX1,P21964,Q96J42,Q14739,Q5H8A4 8 +Hypoplastic labia minora 0.5142410015649541 0.1979588392232054 0.8430772679184457 1.0 1.0 3 Q9NP72,Q15042 2 +Clitoral hypoplasia 0.5142410015649541 0.1979588392232054 0.8430772679184457 1.0 1.0 3 Q9NP72,Q15042 2 +Abnormal circulating albumin concentration 0.2824773716503628 0.1979127302513605 0.8431133438853864 1.0 1.0 32 Q9BT22,Q5XKP0,O95470 3 +Abnormal cardiac test 0.305955145425443 0.1964001614023698 0.8442969699390814 1.0 1.0 18 Q9H3H5,Q9BTV4,P49748,P12235,Q96DA6,P10253,P40939,Q16836,P54098 9 +Tinnitus 0.3042953445132 0.1960859184664587 0.8445429177459092 1.0 1.0 17 P21912,Q02978,Q9NR77,Q15043,Q9H1P3,Q9NR28 6 +Abnormal aortic valve physiology 0.2718542091934907 0.196040033896507 0.8445788313869238 1.0 1.0 41 P04062,Q96PU5,O75844,Q9UHX1 4 +Abnormal muscle fiber type distribution 0.3454280832949345 0.1913011995397753 0.8482896213501081 1.0 1.0 11 Q9H3H5 1 +Muscular dystrophy 0.3009811380302942 0.1908565744621032 0.8486379632518917 1.0 1.0 23 O43505,O14979,P50402,Q9BTV4,O60566,P22626,Q9H5K3 7 +Hereditary nonpolyposis colorectal carcinoma 0.3576802507837131 0.1881565126013326 0.8507539614736652 1.0 1.0 8 P04637,P35222,P63167,O60566,O14965,Q8NFG4,P52701 7 +Rib fusion 0.3491673319551662 0.1869737386005676 0.8516812233826183 1.0 1.0 10 O95202,Q5H8A4 2 +Agammaglobulinemia 0.4652690863579378 0.1864602608360186 0.8520838395800379 1.0 1.0 2 Q8IWT6 1 +Sparse lateral eyebrow 0.3810583385750226 0.1862596791098328 0.8522411255167981 1.0 1.0 7 Q08J23,Q92643,P61978 3 +Arrhinencephaly 0.3442942927069191 0.1859306654326058 0.8524991339467061 1.0 1.0 11 P21964 1 +Generalized hyperreflexia 0.4255855716997793 0.1833503809614396 0.8545231060553089 1.0 1.0 5 P29084 1 +Nasogastric tube feeding 0.2997339326991804 0.1821321186957043 0.8554790431930441 1.0 1.0 23 Q9NZ01 1 +Abnormal z disc morphology 0.4621401752190164 0.179164927100584 0.8578082022034061 1.0 1.0 2 Q13501 1 +Abnormal sarcomere morphology 0.4621401752190164 0.179164927100584 0.8578082022034061 1.0 1.0 2 Q13501 1 +Abnormal rib cage morphology 0.2625698791108878 0.1780311692541783 0.8586984972192351 1.0 1.0 82 O75431,Q10469,Q9BV10,Q8TAA9,O95202,Q14739,Q5H8A4,Q7Z2Z2,Q7RTS9,O75844,Q9UM00,O75718,Q7Z4L5,P15586,P51798,Q9UHX1,Q32P28,Q9UBM7,P08236,P16435 20 +Increased total bilirubin 0.4386769087624039 0.1779126701496741 0.8587915602532166 1.0 1.0 4 P23786 1 +Tissue ischemia 0.3022385120195016 0.1778953295824931 0.858805178797456 1.0 1.0 20 O15460,O75844,Q9Y4P3,Q8NBM4 4 +Rhinitis 0.4016955319975096 0.1758974290861844 0.8603745251537065 1.0 1.0 6 Q9BV10 1 +Anorexia 0.2940757643183959 0.1748475714132381 0.8611994074708802 1.0 1.0 26 Q8NBM4,P04062,P35610,O15460,Q14108,Q13423 6 +Perseveration 0.3769488594536011 0.1709733367637886 0.8642447310509886 1.0 1.0 7 P35637,Q15233 2 +Dilation of virchow robin spaces 0.4583854818523036 0.1706218506830923 0.8645211155045323 1.0 1.0 2 P27635 1 +Abnormality of tibia morphology 0.307640332494489 0.1680221987495942 0.8665658152687328 1.0 1.0 16 Q32P28,Q7RTS9,Q9BV10 3 +Enlarged cisterna magna 0.3012075008810193 0.1679838558145755 0.8665959797895322 1.0 1.0 19 O95298,Q10713 2 +Type ii lissencephaly 0.5009773359899967 0.1672904984299859 0.8671414799443313 1.0 1.0 3 Q9H5K3 1 +Subsarcolemmal accumulations of abnormally shaped mitochondria 0.4344403189054604 0.1666909291044763 0.8676132432035077 1.0 1.0 4 P12235 1 +Hip contracture 0.3339871411654073 0.16415010186177 0.8696129811122901 1.0 1.0 12 Q7LGA3 1 +Abnormal sclera morphology 0.2833953312645186 0.1624903678160965 0.8709197128486987 1.0 1.0 30 Q9H3H5,Q8NCH0,Q8WVQ1,P40939,O75718 5 +Pedal edema 0.3513764349918672 0.1620850725628477 0.8712388611249087 1.0 1.0 8 P04062 1 +Abnormality of complement system 0.4314339386349401 0.1588874991773704 0.8737575097893695 1.0 1.0 4 Q05655,P51570,Q03252 3 +Squamous cell carcinoma of the skin 0.431433938634938 0.158887499177365 0.8737575097893737 1.0 1.0 4 P18074,Q9H4L7,P19447 3 +Trichorrhexis nodosa 0.4967136150234834 0.1579202516565828 0.8745196397901998 1.0 1.0 3 P18074,Q6PGP7 2 +Apneic episodes precipitated by illness fatigue stress 0.4511889862327768 0.1548959524309634 0.8769033446284504 1.0 1.0 2 P53007 1 +Abnormal cortical bone morphology 0.2991579158164698 0.1538037436739168 0.8777644819379888 1.0 1.0 18 P40855,Q86XL3,P51798,P17302 4 +Insulin resistance 0.3048345991082445 0.1517116426389642 0.879414373975127 1.0 1.0 16 Q9Y6M1,P31751,O75431,O75844 4 +Long toe 0.3412581313892165 0.1516612134455441 0.8794541504042173 1.0 1.0 10 Q9UHX1 1 +Focal motor status epilepticus 0.4493116395494227 0.150934271704286 0.8800275652597351 1.0 1.0 2 P54098 1 +Aplasia hypoplasia of the uterus 0.2966026447043798 0.1486908577597326 0.8817975754930514 1.0 1.0 17 Q9NX14,P53701 2 +Abnormal serum insulin like growth factor 1 level 0.4917928491916304 0.1474061532680597 0.8828114489732775 1.0 1.0 3 Q9BV10 1 +Neoplasm of the male external genitalia 0.3475856897087974 0.1467680933010196 0.8833150697667587 1.0 1.0 8 Q13423 1 +Inflammatory abnormality of the eye 0.2671338732513087 0.1458301897222741 0.8840554427134755 1.0 1.0 40 P14174,Q15800,Q8NBM4,P29084,P51648,Q9NZ08,Q14739 7 +Emg myopathic abnormalities 0.2761892207915426 0.1448383720926443 0.8848384851014854 1.0 1.0 32 Q13586,P50402,Q9BTV4,Q9Y5L0,Q9BUK6,P07196,P13473,P12235,Q8NCE2,Q9Y6B6,P54098,P22626 12 +Microdontia 0.2858297971449666 0.1434242765884203 0.8859551112298092 1.0 1.0 28 Q9Y487,Q96A33,Q9UM00,Q9Y4P3,Q6NUK1,Q7LGA3 6 +Jaundice 0.2642928266253715 0.1399464501643525 0.8887023004583534 1.0 1.0 59 Q9H3H5,Q9Y5L0,Q15904,O75648,Q14739,P40855,Q8WWI5,P39210,Q16134,O15118,P56589,P36551,P50542,P28288,Q9Y5U9,P49748,O96011,O75381,Q9UJS0 19 +Central hypoventilation 0.3455210310266377 0.1385436246729434 0.8898107945141223 1.0 1.0 8 O95169,O75306,O43819 3 +Aplasia hypoplasia involving the femoral head and neck 0.337886565095328 0.1369905718538482 0.891038247423205 1.0 1.0 10 O95831,Q8WVQ1,O75431,P50542 4 +Unsteady gait 0.2619812442642698 0.1353263134010411 0.8923538813510468 1.0 1.0 52 O75503,Q86SQ9,Q93063,Q12756,Q9UBB4,P07196,Q10713,Q10469,O75569,Q9NR77,O95831,P49770,P18887,Q9H6K4,Q96DP5,Q08209,Q13144 17 +Abnormal iliac wing morphology 0.3277474857150127 0.1343549851387497 0.8931218754778925 1.0 1.0 12 O95831,P51812,Q7RTS9,Q8TAA9 4 +Hyporeflexia of lower limbs 0.3216190667462276 0.1328221157857615 0.8943340634570673 1.0 1.0 13 P40939,Q9H0B6 2 +Abnormality of the calf musculature 0.3084872080247758 0.1318043697329824 0.8951390301624929 1.0 1.0 15 Q9H5K3 1 +Paranoia 0.4071406201065 0.1304708116596007 0.8961939456467054 1.0 1.0 5 Q96RL7,Q8WYQ5,P36551,P50336 4 +Pectus excavatum 0.2597380062616883 0.1298742995155238 0.8966658780612862 1.0 1.0 80 Q9NSD9,O75431,Q9H490,P50402,Q9BUK6,P21912,Q8NCH0,P04062,Q9BTV4,Q08J23,Q96A33,Q9Y487,Q9UHX1,Q10469,P51812,Q9Y4P3,O75718,Q7LGA3 18 +Osteomyelitis 0.3009245491139859 0.1293218831593284 0.8971029565699462 1.0 1.0 16 P51798,P39210,Q13126,O15269 4 +Abnormality of hair texture 0.2626603225393173 0.128750400561289 0.8975551533793804 1.0 1.0 56 P51798,Q9Y487,Q96A33,P51812,O75844,P29084,P17302,Q9UM00,Q9Y276,Q9NVI7,Q6NUK1 11 +Increased laxity of ankles 0.4380475594492982 0.128391144224834 0.8978394390409197 1.0 1.0 2 O95140 1 +Abnormality of the lymphatic system 0.2485443374532302 0.1280305276441481 0.898124814274496 1.0 1.0 145 P14174,Q8NBM4,Q15904,Q15392,O95202,Q14739,Q96A33,O15118,P36551,Q14108,Q9NZ08,O75845,P51798,Q658P3,Q9BT22,Q9NZJ7,O15460,P23458,P11802,P31751,P04062,P10619,Q9H0U3,Q10713,P21964,P07602,P08236,Q13510,Q96J42,Q01844 30 +Congenital malformation of the left heart 0.4062010648293328 0.1279208664849117 0.8982115976431944 1.0 1.0 5 Q9Y4J8,P17302,O60826,Q8N3U4 4 +Abnormal platelet volume 0.3394399401985443 0.1277095080655582 0.8983788653638953 1.0 1.0 9 Q14739 1 +Pruritus 0.2925262521360217 0.1249769364068279 0.9005418092448401 1.0 1.0 22 Q14739,P16615 2 +Abnormal atrioventricular conduction 0.3135596294912547 0.1235239539837429 0.9016922070058544 1.0 1.0 14 P17302,P21912,P50402,Q9BTV4 4 +Abnormal acetabulum morphology 0.2941430613897752 0.1231641275185442 0.9019771313369148 1.0 1.0 18 Q969X5,Q7RTS9,P08236,O75718 4 +Abnormal femoral head morphology 0.2938618216585947 0.1219759528745864 0.9029180628706176 1.0 1.0 19 Q7Z2Z2,Q7RTS9,O75431,Q7LGA3 4 +Rapidly progressive 0.3380028978028926 0.1218606862514541 0.9030093513426922 1.0 1.0 9 Q14108 1 +Colpocephaly 0.3370139854040682 0.1178611453200148 0.9061776801483918 1.0 1.0 9 P53701 1 +Cerebellar hypoplasia 0.2469440936743735 0.1172676073546576 0.9066479934736982 1.0 1.0 118 O43505,Q9H3H5,Q9BUK6,Q9Y487,O43292,Q9BV10,Q9HC21,Q5H8A4,Q9NXE4,Q5XKP0,Q9UM00,Q9H5K3,Q9H490,P23786,Q9NVI7,Q6NUK1,Q9UBM7,Q10713,P15291,Q96J42 20 +Joint dislocation 0.2549967422556204 0.1169141385051496 0.9069280940857014 1.0 1.0 88 Q8NBU5,Q9UBM7,P51798,Q8NCH0,Q96A33,Q9Y487,O75844,P29084,P21964,Q9UHX1,Q969X5,Q96PU5,Q9NX62,O95202,P51571 15 +Dysmenorrhea 0.4311639549436652 0.1156496680744798 0.9079301975386278 1.0 1.0 2 O00170 1 +Increased circulating gonadotropin level 0.3328105395232179 0.1153573846289436 0.9081618555388014 1.0 1.0 10 P09884,P57740,Q8IY37,Q15031,P82650,P51809,Q14781,P16435,P51659 9 +Abnormality of mouth size 0.2468033191193618 0.1149591193741939 0.9084775251655914 1.0 1.0 118 O75431,Q9Y487,Q15392,Q10469,Q9BUB7,P51571,O75648,Q7LGA3,O75844,P17302,Q9UM00,P15586,Q9H490,Q8NCH0,Q8WVQ1,Q9NVI7,Q6NUK1,Q9UBM7,P04062,P51812,P21964,Q9NX62,Q8NC56,Q8NFG4,Q9Y4P3,P16435,Q01105 27 +Panhypogammaglobulinemia 0.382253228416352 0.1146318387612814 0.9087369423686432 1.0 1.0 6 P18074,P29084 2 +Delayed ability to walk 0.2614733609474802 0.1099230943694647 0.9124703668702876 1.0 1.0 70 P21912,Q99720,Q10713,Q86VD7,Q96N66,Q5H8A4 6 +Localized skin lesion 0.2470351722196306 0.1088890667830921 0.9132904785223936 1.0 1.0 223 Q9H3H5,O75431,Q8NBM4,Q15392,Q8TAA9,O95202,O75648,Q14739,Q06136,Q5H8A4,Q7LGA3,P39210,O75844,O15269,Q96HR9,Q9UM00,P98194,P38435,Q9NWM8,Q8NCH0,Q658P3,Q9UHX1,Q03519,Q96PU5,Q9NZJ7,Q6NUK1,O15460,P16615,P11802,P21912,P04062,P53701,P21964,Q969X5,P07602,P35637,Q9Y4P3,Q13510,Q9NX14 39 +Supernumerary spleens 0.334304176295409 0.1070091364631274 0.9147817315278935 1.0 1.0 9 Q96J42,O95202 2 +Severely reduced visual acuity 0.4710485133020442 0.1066696362037399 0.9150510719330828 1.0 1.0 3 P20839,P35222 2 +Erythrocyte inclusion bodies 0.3980582524271971 0.1064263309773598 0.915244102612945 1.0 1.0 5 Q13586,P11413,O14936,P08865 4 +Thick hair 0.379283545703781 0.1058445233104598 0.9157057106806936 1.0 1.0 6 Q9Y487 1 +Skin ulcer 0.2761585194435247 0.1051908757171571 0.9162243506778384 1.0 1.0 30 P39210,P04062,O15269,Q03519,Q14739 5 +Aplasia hypoplasia involving the metacarpal bones 0.2824270406497037 0.1031560057933962 0.9178391558632056 1.0 1.0 27 Q7RTS9,P51812,Q8WVQ1,Q9NX62,Q14739,P16435,Q32P28 7 +Abnormality of the proximal phalanx of the thumb 0.4236545682102561 0.1026400488643536 0.9182486562818064 1.0 1.0 2 Q15233 1 +Symphalangism of middle phalanx of finger 0.4236545682102561 0.1026400488643536 0.9182486562818064 1.0 1.0 2 Q15233 1 +Frontal balding 0.4236545682102463 0.1026400488643374 0.9182486562818192 1.0 1.0 2 Q96CW1 1 +Short palpebral fissure 0.2822098953269998 0.1015841556497861 0.919086756342276 1.0 1.0 27 Q6NUK1,Q9NXE4,O75844,Q9UHX1 4 +Apraxia 0.2609034236900458 0.1005680502422312 0.9198933602973624 1.0 1.0 60 Q8N0X7,O96008,Q6DKK2,O14773,P04062,O43292,Q10713,Q7LGA3 8 +Abnormal endocardium morphology 0.3021541139941247 0.0980637761198457 0.9218816513144016 1.0 1.0 15 P04062,Q9NZ08,Q9Y4P3,Q8NBM4 4 +Abnormality of the pancreas 0.2593872068390775 0.0969901343159424 0.9227342291858616 1.0 1.0 74 P11802,Q7Z2Z2,P14174,P03886,Q9UGP8,Q8NBM4,P00403,P09601,Q15904,Q9UHX1,P03915,Q96J42,Q14739,Q01844,Q9NQH7 15 +Impaired antigen specific response 0.328240747562574 0.096366809444136 0.9232292516354784 1.0 1.0 10 Q9H0U3,Q9BV10,Q13546 3 +Cerebellar cyst 0.2623939780757025 0.0956275228393442 0.923816405303213 1.0 1.0 38 Q9UBM7,Q9Y487,P15291,P23786,Q96J42,Q9H5K3 6 +Respiratory failure requiring assisted ventilation 0.3751787745985671 0.0939582890520168 0.9251422906147264 1.0 1.0 6 P10253,O75648 2 +Tall stature 0.2591096667543854 0.0935410664471868 0.9254737263873208 1.0 1.0 55 Q9NWM8,Q8NCH0,P51530,O95202,Q13423,P16435,Q5H8A4,Q7LGA3 8 +T lymphocytopenia 0.330188817025587 0.0908358442860114 0.9276230281505828 1.0 1.0 9 Q9H0U3,Q13432,Q13546 3 +Delayed gross motor development 0.2442814094103585 0.090725431966574 0.9277107621761932 1.0 1.0 113 Q9H0B6,P21912,Q99720,Q8NCH0,Q10713,Q86VD7,Q96N66,Q5H8A4,Q01105,Q7LGA3 10 +Mesomelia 0.3732793898232737 0.0885615641183561 0.9294303554020896 1.0 1.0 6 Q14739 1 +Pain insensitivity 0.390743760813953 0.0880601457390696 0.9298288723690548 1.0 1.0 5 P39210 1 +Abnormal vitreous humor morphology 0.3321980877818258 0.0875794755531094 0.930210915621722 1.0 1.0 8 Q9NX14,P53701 2 +Elevated urinary dicarboxylic acid level 0.4593111266956796 0.0862140648494363 0.9312962502049756 1.0 1.0 3 P36551 1 +Respiratory paralysis 0.4593111266956796 0.0862140648494363 0.9312962502049756 1.0 1.0 3 P36551 1 +Porphyrinuria 0.4593111266956796 0.0862140648494363 0.9312962502049756 1.0 1.0 3 P36551 1 +Episodic pain 0.3061135779463024 0.0861464932707402 0.9313499646837252 1.0 1.0 14 Q13423,P21912 2 +Abdominal pain 0.2543132149058846 0.0859338291641672 0.9315190191835928 1.0 1.0 85 P42892,P14174,Q12769,Q9UGP8,P21912,P04062,Q8NBM4,O15460,P35637,Q14108,P36551,Q70HW3,P23786,Q9Y4P3,Q13423,Q01844,Q14566 17 +Short nose 0.2473206931134974 0.085659158786059 0.9317373693143394 1.0 1.0 96 P42892,Q9H490,O75845,P38435,P04062,Q8NCH0,Q9Y487,O75844,Q15392,Q9UHX1,Q9NX62,Q9NVI7,Q6NUK1 13 +Heterotaxy 0.3719929603123167 0.0849439359384792 0.9323059621608608 1.0 1.0 6 Q5H8A4 1 +Atypical absence seizure 0.458528951486706 0.0849176082030963 0.9323268930285038 1.0 1.0 3 Q05086,Q96CW1 2 +Atrioventricular canal defect 0.3253104643512254 0.0844400965670363 0.932706528653928 1.0 1.0 10 Q9UBM7,Q9UHX1 2 +Low set posteriorly rotated ears 0.256135529702287 0.0830659864688273 0.9337990712137004 1.0 1.0 80 P40855,O75381,Q9UBM7,P04062,Q8NCH0,Q10713,Q15392,Q6NUK1,Q10469,Q4J6C6,P56589,O95202,Q9UM00,Q9Y4P3,Q96J42,P37268,P16435,Q5H8A4 18 +Hypotelorism 0.2611921832027498 0.0818547321901252 0.9347622320626529 1.0 1.0 36 Q9NSD9,Q13586,Q9NXE4,Q9BUK6,Q08J23,P54886,Q15904,P29084,P17302,Q15042,Q5T8D3,P18074,P55795 13 +Impaired distal proprioception 0.3973074514715037 0.0800037593558849 0.9362342660236168 1.0 1.0 4 Q96RR1,P54098,O14802 3 +Large beaked nose 0.3699874686716904 0.0793650203284861 0.936742290583482 1.0 1.0 6 O75792,O14802,P18074,Q9Y3Z3,Q12797 5 +Abnormal foot bone ossification 0.4547819809265789 0.078822231875457 0.9371740205818504 1.0 1.0 3 Q14739 1 +Hypergalactosemia 0.45320813771519 0.0763187445147241 0.9391655133685716 1.0 1.0 3 P51570,Q9UJS0 2 +Increased circulating androgen concentration 0.4058197747183862 0.0753989288952553 0.9398973114033282 1.0 1.0 2 P04637 1 +Long penis 0.4058197747183852 0.0753989288952539 0.9398973114033292 1.0 1.0 2 O00170 1 +Nail dystrophy 0.2722500781163076 0.0750417204012234 0.9401815173732933 1.0 1.0 30 O75844 1 +Oral pharyngeal dysphagia 0.3037043323974548 0.0743705743610144 0.9407155222030305 1.0 1.0 14 Q13510 1 +Malignant hyperthermia 0.394489668127735 0.0743104804329798 0.9407633379105922 1.0 1.0 4 P50570,P36871,Q8NCE2 3 +Megaloblastic anemia 0.3284039926017586 0.0737658078246832 0.9411967342778504 1.0 1.0 8 P41440,O76024,P00374 3 +Hemoptysis 0.3838859993932786 0.0716676914927017 0.942866368476134 1.0 1.0 5 Q8NBM4 1 +Kyphoscoliosis 0.2566168958101188 0.0707251961274105 0.9436164674369436 1.0 1.0 54 Q8NBU5,Q8N0X7,Q9NWM8,Q9Y487,Q8NCH0,Q10469,Q9NR77,O75844,P51530,Q8TB36 10 +Thickened calvaria 0.3247386505161405 0.0700055574740857 0.9441892362675964 1.0 1.0 9 Q7RTS9 1 +Neoplasm of the thyroid gland 0.2845853646016735 0.0694603131136878 0.9446232218684424 1.0 1.0 21 P21912 1 +Metatarsus adductus 0.3129572958093795 0.0673476928931981 0.9463049096082848 1.0 1.0 12 P08236,O95202,Q9UBM7,Q15392 4 +Incomitant strabismus 0.2895910838306176 0.0668500714887966 0.9467010612465478 1.0 1.0 16 O75648,Q7LGA3 2 +Aplasia hypoplasia involving the pelvis 0.2824923559926126 0.0660917528383624 0.9473047767781866 1.0 1.0 17 O75431,Q8WVQ1,O95202,O95831,Q5H8A4,Q15738 6 +Dry skin 0.261550890092934 0.0628507618246228 0.9498853436471972 1.0 1.0 34 P11802,O96011,P52732,P00813,Q08J23,Q06136,P29084,P17302,P18074,P51648,Q2TAA5,P37268,O75352 13 +Genu varum 0.3198029646924588 0.0625721821292864 0.9501071814412528 1.0 1.0 10 Q7Z2Z2,Q7RTS9 2 +Congenital diaphragmatic hernia 0.2818510834760115 0.0621067588906763 0.9504778145750764 1.0 1.0 23 Q9NX14,P53701,O95202,Q5H8A4 4 +Abnormality of the spinal cord 0.2561842273010497 0.061448954512754 0.951001665928151 1.0 1.0 75 O75845,Q10713,P29084,Q9UHX1,P21964,Q8TAA9,P51530,O95202,Q9HC21,Q9Y4P3,Q5H8A4,O75298 12 +Advanced eruption of teeth 0.3159316442876818 0.0604983236951158 0.9517587509038 1.0 1.0 11 Q9UBM7,O75844 2 +Abnormality of taste sensation 0.3942428035043701 0.0603804025344414 0.9518526666872325 1.0 1.0 2 Q12756 1 +Vertical nystagmus 0.3933041301626935 0.0592512574466766 0.9527519837836392 1.0 1.0 2 P50542 1 +Alkalosis 0.3863494051346237 0.0585791268902816 0.9532873364561464 1.0 1.0 4 P01889,Q96I59,O00170 3 +Cranial nerve compression 0.3105841306675588 0.0571063558735623 0.9544604734329524 1.0 1.0 12 Q02978,P51798,P21912 3 +Amblyopia 0.2827112500021894 0.0561135018352358 0.955251387977341 1.0 1.0 18 Q9UHX1 1 +Posterior subcapsular cataract 0.3612326486047071 0.0558909549117302 0.9554286765026716 1.0 1.0 6 Q9H6K4 1 +Tetraplegia 0.3049428894484199 0.0542148248906439 0.9567640095008324 1.0 1.0 13 P54886,P51572,O43681,O95831,Q13423,P51970 6 +Hyperorality 0.3751957406827499 0.0520638908739055 0.9584777848332426 1.0 1.0 5 P55072,Q05086,Q14203,Q13501 4 +Pseudoepiphyses of the metacarpals 0.3825738329778451 0.0516441722989512 0.958812221875305 1.0 1.0 4 O95202 1 +Pseudoepiphyses of hand bones 0.3825738329778451 0.0516441722989512 0.958812221875305 1.0 1.0 4 O95202 1 +Micromelia 0.2809835364575818 0.0511028210340864 0.9592435880718652 1.0 1.0 22 Q7Z4L5,Q14739,Q9UHX1 3 +Cone shaped epiphysis 0.3134838918899771 0.0505608902787015 0.9596754279780656 1.0 1.0 11 Q7RTS9 1 +Abnormality of lower limb epiphysis morphology 0.2864178580894452 0.0500557767394906 0.9600779405804608 1.0 1.0 16 Q7LGA3 1 +Constriction of peripheral visual field 0.2793773865855257 0.0463410955870824 0.9630383849340458 1.0 1.0 23 Q9H061,P40855,O75381,P00846,O60313,P56589 6 +Miosis 0.4322378716745011 0.0461266474685532 0.963209306999914 1.0 1.0 3 Q13586,Q6XZF7 2 +Synostosis involving digits 0.3782091421415142 0.0439123082231359 0.9649743042223616 1.0 1.0 4 O60828,Q15233,Q9H1A4 3 +Congenital bilateral hip dislocation 0.3792240300375307 0.0438419241675393 0.9650304085415812 1.0 1.0 2 Q9Y4R8 1 +Macrodontia of permanent maxillary central incisor 0.42981005527612 0.0430052798293997 0.9656973250539762 1.0 1.0 3 P17302 1 +Abnormal globus pallidus morphology 0.3114844811600362 0.0425580955996484 0.9660538000711822 1.0 1.0 11 Q8WWI5,O75306,O43819 3 +Elevated circulating alanine aminotransferase concentration 0.314541276989185 0.0423721299157131 0.9662020454943095 1.0 1.0 10 Q15904,P10253,O75880 3 +Aplasia hypoplasia of the pubic bone 0.3551643243315857 0.0404754265776863 0.9677140977335684 1.0 1.0 6 Q5H8A4 1 +Rectal prolapse 0.3160874578691149 0.0383785412852363 0.969385869948914 1.0 1.0 9 Q08J23,P51812,Q9Y4P3 3 +Split nail 0.3684067469926457 0.0376687128673174 0.969951821799082 1.0 1.0 5 P29084 1 +Abnormality of the dorsal column of the spinal cord 0.4245436843716095 0.0364947797371106 0.9708878411046636 1.0 1.0 3 Q8WVX9 1 +Short sternum 0.4241001564945319 0.0359626012969658 0.9713121794933568 1.0 1.0 3 O60566,Q6KC79 2 +Aplasia hypoplasia of the sternum 0.4241001564945319 0.0359626012969658 0.9713121794933568 1.0 1.0 3 O60566,Q6KC79 2 +Long fingers 0.2533749349970437 0.0353796673144676 0.9717769976930206 1.0 1.0 77 P42892,Q9H3H5,Q8NCH0,Q9BV10,P21964,Q9UHX1,P16435,P23786,Q06136,Q5H8A4 10 +Abnormal lateral ventricle morphology 0.2603841014212195 0.0344942158263577 0.9724830547071311 1.0 1.0 33 O75340,Q5H8A4,Q01105,P53701 4 +Hypoplasia of the musculature 0.3354910134803398 0.0344835854843862 0.9724915314498908 1.0 1.0 7 Q9Y487 1 +Abnormal metacarpal morphology 0.2624914212650374 0.0343362288690661 0.9726090354326762 1.0 1.0 32 Q7RTS9,P51812,Q8WVQ1,P08236,Q9NX62,Q14739,P16435,Q32P28 8 +Abnormal form of the vertebral bodies 0.2499586440675425 0.0340596156210239 0.9728296118523532 1.0 1.0 86 Q9BV10,Q8TAA9,O95202,O15228,Q14739,Q5H8A4,Q7RTS9,P17302,Q9UM00,P15586,O75845,P51798,Q9UHX1,Q6NUK1,Q32P28,Q9UBM7,P51812,Q10713,P08236,Q9Y4P3,P16435 21 +Hyperuricemia 0.3148184820115066 0.0338926910891047 0.9729627215073644 1.0 1.0 9 P35610,P49257 2 +Wide nose 0.2555004194580373 0.0336819598522301 0.973130764762363 1.0 1.0 37 P52732,P53701,P51812,Q9BV10,O60566,Q9UM00,Q9NX14,Q12797,Q5H8A4 9 +Renal cyst 0.2550593813460683 0.0319179521612441 0.9745374821788876 1.0 1.0 63 O43505,P40855,Q16134,P56589,Q15056,P61619,Q9UHX1,O60566,P23786,Q9NQH7,Q9NWS8,O75381,Q9UGP8,Q9UBM7,Q10713,P21964,Q8NFG4,Q9Y4P3,Q96J42 19 +Moderate albuminuria 0.4199231685249818 0.0310722545670619 0.9752119166295684 1.0 1.0 3 Q5JRA6 1 +Abnormal length of corpus callosum 0.3645181476845954 0.0306328575424372 0.9755623379095248 1.0 1.0 2 P48449 1 +Multifocal cerebral white matter abnormalities 0.3697557921102024 0.0298037011273667 0.976223607006644 1.0 1.0 4 O75792,Q9Y3Z3,P10253 3 +Abnormal cerebral cortex morphology 0.2435614146064773 0.0294346589645933 0.976517930916048 1.0 1.0 225 Q9H3H5,Q9Y487,Q15392,Q9BV10,Q9BUB7,Q9HC21,O75648,Q96N66,P03886,Q7LGA3,Q96AA3,P40855,O75503,P00403,P51572,P29084,Q9UM00,Q9NZ01,Q9H5K3,Q86XL3,P03915,Q96PU5,P23786,P37268,Q9NWS8,P00846,O75381,O96008,Q9UBM7,P04062,P51812,Q10713,O75306,O43819,Q9Y320,P35637,Q9Y4P3,Q01105 38 +Decreased activity of mitochondrial complex iii 0.3493107769423689 0.0262808890864807 0.979033297946396 1.0 1.0 6 Q5JPH6,P53597,P43897,Q9H0R6,Q96RP9 5 +Lipid accumulation in hepatocytes 0.253763130454721 0.0251956152454737 0.9798989343746942 1.0 1.0 73 O75431,Q7KZN9,Q15904,Q15067,O75648,P40939,Q8N511,Q5XKP0,Q16134,P39210,P55263,Q9Y276,Q16836,P22626,Q9NSD9,Q9Y375,P49748,Q9Y6B6,P23786,Q5JPH6,P31751,Q9NWS8,Q9UJS0,Q9P2J5,Q96DA6,P50416,O75880 27 +Central primitive neuroectodermal tumor 0.3570087609511738 0.0249323112370221 0.9801089545992784 1.0 1.0 2 P04637 1 +Choriocarcinoma 0.3570087609511738 0.0249323112370221 0.9801089545992784 1.0 1.0 2 P04637 1 +Abnormality of the ureter 0.2545591986400993 0.024813196488004 0.9802039650245972 1.0 1.0 66 Q9UBM7,P21912,Q86XL3,O75844,Q9UHX1,P21964,Q8TAA9,P23786,Q96J42,P16435,Q7LGA3 11 +Finger swelling 0.3566958698372844 0.0247092031051431 0.980286914306464 1.0 1.0 2 Q01968 1 +Congenital malformation of the right heart 0.3317616266798163 0.0239365310682842 0.9809032350446962 1.0 1.0 7 P40855 1 +Abnormality of the lower urinary tract 0.2432784902456717 0.023318504121719 0.9813962115720344 1.0 1.0 225 Q99720,P07196,Q9BV10,Q9BUB7,Q8TAA9,O95202,P51571,Q9BRK0,Q5H8A4,O75298,P40855,Q8WWI5,O75844,Q9NR77,P12235,Q3ZCQ8,P56589,Q8N0X7,Q9UBX3,Q9NWM8,Q8NCH0,Q9UBB4,Q86XL3,Q9UHX1,O43681,Q9NZJ7,P37268,O75381,Q9UBM7,P21912,P04062,P53701,P51812,P21964,P07602,P35637,Q9Y4P3,Q9NX14,Q96J42,P16435 40 +Overweight 0.3611024115252157 0.0230876714407042 0.9815803398314756 1.0 1.0 5 P49748,Q01082,Q9HCK8,Q93009 4 +Distal upper limb amyotrophy 0.2867893455074647 0.0210011975313331 0.9832447003954106 1.0 1.0 15 Q9BQT8,Q8TB36,Q9NR77 3 +Large hands 0.305857203154111 0.0206004187624168 0.9835644064136252 1.0 1.0 11 P51812,O00170,P21912 3 +Abnormal waist to hip ratio 0.346730020722914 0.0202353993073191 0.9838555890975764 1.0 1.0 6 Q9Y6M1,P31751,O76024 3 +Abnormality of vitamin a metabolism 0.3589707533483711 0.0190098806589316 0.9848332232087842 1.0 1.0 5 Q7Z2Z2 1 +Macule 0.253955391123195 0.0188134119240537 0.984989954548755 1.0 1.0 64 Q06136,O75844,P21912,P16615 4 +Head titubation 0.3299072572171543 0.0188058171417633 0.9849960132364056 1.0 1.0 7 Q99720 1 +Milia 0.4078247261345936 0.0181206367694831 0.9855426148924584 1.0 1.0 3 Q9H4L7,P50336 2 +Intractable diarrhea 0.4078247261345926 0.0181206367694822 0.9855426148924592 1.0 1.0 3 Q15477,Q6PGP7 2 +Hypoplastic fingernail 0.2963468362947108 0.016644227364369 0.9867204411023492 1.0 1.0 13 P51812,Q14739 2 +Sound sensitivity 0.3112927371656055 0.0156147201253838 0.987541762152944 1.0 1.0 8 P17900,Q9Y4P3 2 +Hyperacusis 0.3112927371656055 0.0156147201253838 0.987541762152944 1.0 1.0 8 P17900,Q9Y4P3 2 +Hypoplastic hippocampus 0.3423028785982386 0.0156110633788027 0.9875446794589976 1.0 1.0 2 Q96RL7 1 +Muscle hypertrophy of the lower extremities 0.3110991670925273 0.0149972492171121 0.9880343749432152 1.0 1.0 8 Q9NR77,Q8NCE2 2 +Weakness of long finger extensor muscles 0.4043818466353782 0.0147552356252464 0.9882274524857362 1.0 1.0 3 Q13501,Q9Y223 2 +Myoglobinuria 0.3068498132217339 0.0141122226329843 0.9887404491760868 1.0 1.0 10 P40939,Q16836 2 +Portal fibrosis 0.3582797172371537 0.0124578000759192 0.9900603707582668 1.0 1.0 4 P55263 1 +Elevated circulating aspartate aminotransferase concentration 0.2997832598078214 0.0124247469591682 0.9900867412888436 1.0 1.0 12 P40939,O75880 2 +Interictal eeg abnormality 0.2487219976033729 0.0116458154442407 0.9907081936931208 1.0 1.0 85 Q8NBU5,Q9H936,Q9UBX3,Q9H3H5,O75503,Q9UBB4,Q10469,P13073,Q3ZCQ8,O75340,Q9NQZ5,P00367,Q14108,Q2TAA5,Q96N66,Q5H8A4,Q9NZ01 17 +Abnormal patella morphology 0.2719211151288734 0.0111340004259467 0.991116536501732 1.0 1.0 25 Q9NX62,P21964 2 +Neoplasm of the larynx 0.357232310582342 0.0109768857352544 0.9912418882269268 1.0 1.0 4 P04637,P52701,P43246 3 +Somatic mosaicism 0.3313516896120054 0.0100887988183614 0.9919504397385694 1.0 1.0 2 P00813 1 +Bilateral cryptorchidism 0.307854373140663 0.0099954715143701 0.9920249003989304 1.0 1.0 9 P27635,P37268,P48449,Q96DA6 4 +Enterocolitis 0.3304130162703281 0.0096664694473973 0.9922873933824417 1.0 1.0 2 P49748 1 +Night sweats 0.330100125156436 0.0095273961556006 0.9923983527048404 1.0 1.0 2 Q9UJS0 1 +Spondyloepiphyseal dysplasia 0.3285356695869741 0.0088446539906312 0.9929430791433732 1.0 1.0 2 P27635 1 +Bladder diverticulum 0.309117510920865 0.0087294938169196 0.9930349601206904 1.0 1.0 8 Q9NWM8,Q9Y4P3 2 +Chronic constipation 0.2713227730629342 0.0073088837572673 0.9941684064138292 1.0 1.0 25 P04062 1 +Peptic ulcer 0.3014649491788181 0.0040579678618389 0.9967622189809526 1.0 1.0 11 P04062,O76024,Q15056,Q9Y4P3 4 +Vertebral wedging 0.3906103286385082 0.0026431575187457 0.997891067879622 1.0 1.0 3 Q15436,Q8WVQ1 2 +Squamous cell carcinoma 0.2925366109806565 0.0006879970740698 0.9994510578000282 1.0 1.0 13 P14324,P53634,P29084 3 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e4cc88a1a664dc48819b224cb0288bc728471261 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular connection", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the 5th finger", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Acute rhabdomyolysis", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Adult onset sensorineural hearing impairment", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central opacification of the cornea", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal eosinophilia", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonadotropin deficiency", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemoptysis", "Hemorrhage of the eye", "Hemothorax", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent macular lesion", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypoautofluorescent retinal lesion", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic iris stroma", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired renal concentrating ability", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Increased vldl cholesterol concentration", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intervertebral space narrowing", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal perforation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Menorrhagia", "Mental deterioration", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Non hodgkin lymphoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid dysgenesis", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripapillary chorioretinal atrophy", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Persistent pupillary membrane", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posterior uveitis", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of finger phalanx", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Sex reversal", "Shagreen patch", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous pneumothorax", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical body rocking", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supernumerary vertebrae", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "Systolic heart murmur", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Thinning of descemet membrane", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACY1", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG12", "ANAPC1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARPC1B", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATL3", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATP8", "ATXN10", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCKDHB", "BCS1L", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1B", "BUB3", "BUD23", "C12orf57", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CAPN1", "CARS", "CASK", "CBL", "CBX2", "CCDC22", "CCDC47", "CCNK", "CCT5", "CD2AP", "CDC40", "CDC42", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDK6", "CELF2", "CEP290", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK2", "CHMP2B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CLASP1", "CLCC1", "CLCN7", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "CNP", "COA3", "COA7", "COASY", "COG8", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COQ8B", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2A1", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CUL3", "CUL4B", "CWC27", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "DAG1", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DEGS1", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIP2B", "DKC1", "DLAT", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB11", "DNAJC13", "DNAJC19", "DNAJC3", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK7", "DOLK", "DPAGT1", "DPM1", "DPP9", "DPYSL5", "DSG2", "DSP", "DST", "DTNA", "DYM", "DYNC1H1", "DYNC1I2", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMC10", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "FAH", "FAM50A", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FIP1L1", "FKBP10", "FKBP14", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GBA", "GBE1", "GCDH", "GCLC", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GIPC1", "GJA1", "GLA", "GLB1", "GLDC", "GLE1", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GNAI2", "GNAI3", "GNE", "GNPAT", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GPKOW", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2E2", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HELLS", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFT27", "IGF2BP2", "IGF2R", "IMPAD1", "IMPDH1", "INF2", "INTS1", "IRF2BPL", "IRS4", "ITM2B", "ITPA", "IVD", "JAGN1", "JAK1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIAA0319L", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KLC2", "KMT2A", "L2HGDH", "LAMB1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LIPA", "LLGL1", "LMAN1", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LRRC8A", "LSS", "MACF1", "MAGED2", "MAGT1", "MALT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MED23", "MESD", "MFN2", "MGAT2", "MIA3", "MICU1", "MID1", "MIF", "MIPEP", "MMAB", "MOGS", "MORC2", "MPDU1", "MPG", "MPI", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTFMT", "MTHFD1", "MTHFS", "MTMR14", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NARS2", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND1", "ND5", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEK9", "NELFA", "NEMF", "NF1", "NFS1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPM1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OBSL1", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSBPL2", "OTULIN", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PAK1", "PALLD", "PANX1", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCNA", "PDCD6", "PDHA1", "PDHB", "PDK3", "PDXK", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POMK", "PON2", "POP1", "POR", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PSPH", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRSL1", "RAB18", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RAD51C", "RALA", "RANBP2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "REEP2", "REEP6", "RFC1", "RFC2", "RFT1", "RHOA", "RINT1", "RIPK1", "RMND1", 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sha256:ffaa64706a653c933504e225408e3ede363d4d575975721a3830ffb47e93802a +size 88652 diff --git a/msigdb_kegg/df_merge.tsv b/msigdb_kegg/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6034d737bb71e7784f5eb4b8a382ab2ed6511daa --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,15 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Lysosome 21 43 3.534904468990626 0.0004079226058022 21.740291262135923 48.609223300970875 0.8281821627988494 0.1302152537326229 7.142313942893836 4.247239237941681 3.086075071395461 0.2389623217115766 4.78939358308702e-06 0.3807425591661329 0.242627214008706 0.0001318832384526 1.8700693912890145e-05 +Parkinsons disease 17 58 3.278084597267769 0.0010451406800768 16.90776699029126 54.04126213592233 1.0315348591123816 0.3152611195514452 7.595108151251147 4.223805209268991 1.8494970521239744 0.3626807692210581 5.763496226750126e-08 0.0001278661716502 5.674696969044666e-06 2.1987056777748843e-08 1.5035038562276313e-08 +Oxidative phosphorylation 21 62 3.233665676690028 0.001222124277711 18.79854368932039 59.0752427184466 1.0149760730411637 0.3252836463038503 7.263801581344288 4.652138947381941 1.8018345229041028 0.3643612228552857 2.2978793913757494e-10 0.0001278661716502 5.3362179258556514e-05 2.802580353049737e-09 4.6082416761976156e-10 +Glycerophospholipid metabolism 9 18 3.199679932673105 0.0013758027950947 5.553398058252427 16.104368932038835 0.8448777148315795 0.3373638196000335 3.045697762577092 2.514285464673758 1.2272389207362138 0.3056726473181033 3.166933515555171e-05 0.2295798469686227 0.0145863017156454 0.0018183768983854 0.0002197719354354 +N glycan biosynthesis 12 21 2.693271717488146 0.0070754580030811 5.849514563106796 16.08252427184466 0.2628189875288922 0.4633396270200485 3.100528416799328 2.9026244296339763 1.1828065880862877 0.3297121354639235 0.0001343504582756 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6.454974629594755e-08 +Sphingolipid metabolism 8 13 2.286706058163434 0.0222129858590862 5.672330097087379 11.759708737864075 0.9805985471070467 0.1821702203806468 2.452838935293596 1.3449033287601222 1.7625559835482287 0.2542774311591588 3.001374474122689e-05 1.0 1.0 0.0028063338575205 1.4501208960420526e-05 +Biosynthesis of unsaturated fatty acids 6 11 2.2803399139225204 0.022587536275006 3.866504854368932 9.87135922330097 0.446353222362544 0.4068046635290026 2.037070144655868 1.3349139447509937 1.1010511542611248 0.297846720070728 5.714174158713829e-06 1.0 0.1741653971767485 0.0116756742779249 2.6131601312709008e-05 +Snare interactions in vesicular transport 10 14 2.27819541814782 0.0227149371534338 5.803398058252427 13.6626213592233 0.8920027438628428 0.3386294703372389 3.103034547770364 2.9171839264116786 1.2201519782198902 0.3219991979242683 0.0100603059721957 1.0 0.043496878178469 0.0014099836558107 0.0060226058745804 +Porphyrin and chlorophyll metabolism 6 14 2.1789611902762416 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0000000000000000000000000000000000000000..2c1b2f9ed07952719ef9867ca2db001c17a2a388 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 178, + "title": "Average number of proteins per term", + "value": 16.702247191011235 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2c2fe89da7fbde7a50d941cff3af54ac0ee44227 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ed0537ce4500d88006b2763f42b7175177ca369a --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,57 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size 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0.6486498917106405 2.693271717488146 0.0070754580030811 0.7174523812738194 0.1049526270457042 21 Q96AA3,Q9H3H5,Q9BT22,Q16706,P15291,Q10469,P46977,Q9BV10,Q86YN1,O75340,Q2TAA5,Q8TCJ2 12 +Huntingtons disease 0.4520545029746045 2.572574356296825 0.0100945269472441 0.8356827629709501 0.1290012682295551 77 P00846,P21912,O95298,P00403,O96000,P13073,Q9Y6M9,P12235,O14949,P45880,Q9Y277,P21796,P36542,O43676,Q9UDW1 15 +Protein export 0.6662163245569549 2.4056634589176356 0.0161431283210582 0.9448072108422744 0.1684691172213012 15 Q99442,P67812,P61619,Q9Y5M8,Q15070,Q15005 6 +Steroid biosynthesis 0.7313591542754622 2.3339412608645524 0.0195987978442446 0.9704958811366704 0.1684691172213012 11 Q15800,O75845,P35610,Q14534,Q15392,Q16850,P37268 7 +Sphingolipid metabolism 0.6851790751852876 2.286706058163434 0.0222129858590862 0.9816566269552154 0.1684691172213012 13 P04062,Q16739,O15269,O43681,Q16880,Q13510,Q06136,O95470 8 +Biosynthesis of unsaturated fatty acids 0.7210873341550825 2.2803399139225204 0.022587536275006 0.9828658979764696 0.1684691172213012 11 O00767,O15254,Q15067,Q53GQ0,P40939,Q9NZ01 6 +Snare interactions in vesicular transport 0.6644523603741155 2.2781954181478197 0.0227149371534338 0.9832588825438324 0.1684691172213012 14 O14653,O75396,Q9UNK0,O60499,O95249,Q12981,Q9P2W9,Q13190,O15400,O15498 10 +Porphyrin and chlorophyll metabolism 0.6473950210588375 2.1789611902762416 0.0293345514173428 0.9950067463853316 0.2088620060914812 14 P09601,P53701,Q7KZN9,P30519,P22830,P08236 6 +Steroid hormone biosynthesis 0.9436795994993762 2.143295134865242 0.0320894072484656 0.9969892602670616 0.2133519247211438 2 P21964 1 +Cardiac muscle contraction 0.5692277342499317 2.1202869319769815 0.0339818550448929 0.9978748942646938 0.216027507071105 20 O14949,P13073,P16615,P00403 4 +Calcium signaling pathway 0.5541578178042967 1.983404926296083 0.0473222173045417 0.9998211888398064 0.233619550707884 19 P12236,P05141,P12235,Q9Y277,P45880,P21796,P20020,P16615 8 +Abc transporters 0.7018808777429528 1.9554830167285453 0.0505260859993395 0.9999018295797484 0.233619550707884 8 P28288,P08183,Q9NUT2,O75027,Q03519,O14678,P33527 7 +Alzheimers disease 0.4087760218073444 1.8329416556717757 0.0668112481190177 0.9999954859103034 0.2831524325044084 59 P00846,P00403,O95298,P21912,O96000,P13073,Q9Y6M9,O14949,P36542,O43676,Q9UDW1,P16615 12 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.7571774663465438 1.7481710233905154 0.0804344175559979 0.9999996706011778 0.3046239643610133 6 Q5H8A4,O43292,Q9H490 3 +O glycan biosynthesis 0.786818132852143 1.6878205353920008 0.091445684354855 0.9999999614113644 0.3149093629573532 5 Q8N4A0,Q10472 2 +Glycosaminoglycan biosynthesis keratan sulfate 0.8401126408010005 1.6849615313673707 0.0919959936729346 0.9999999653564712 0.3149093629573532 2 P15291 1 +Riboflavin metabolism 0.809283781723229 1.637007174356628 0.1016289705167761 0.9999999948105488 0.3349991991108546 4 Q9NPH0 1 +Glycosphingolipid biosynthesis lacto and neolacto series 0.8403755868544613 1.3684995147412429 0.1711557737897153 0.9999999999999968 0.4547123542473035 3 Q11206,P15291 2 +Nicotinate and nicotinamide metabolism 0.7100213777559083 1.3495090678830324 0.1771735097166633 0.9999999999999992 0.4637777166112658 5 P49902,P43490 2 +Proximal tubule bicarbonate reclamation 0.6045919309423636 1.236990126785363 0.2160907480945555 1.0 0.5230696079548584 7 P00367,Q9UBX3 2 +Primary immunodeficiency 0.7381101376721124 1.2255227546144989 0.2203783220589066 1.0 0.5230696079548584 2 Q03519 1 +Renin angiotensin system 0.7119201002976394 1.2223466838686534 0.2215765521889863 1.0 0.5230696079548584 4 P10619 1 +Vibrio cholerae infection 0.438887833588708 1.2045581453692438 0.2283739226505459 1.0 0.5254409391914454 21 Q93050,Q96HE7,P61619,Q9Y487,P24390,Q15904 6 +Glycosaminoglycan biosynthesis heparan sulfate 0.7655694361403287 1.0666980289153989 0.286108217495636 1.0 0.6139340279428331 3 Q7LGA3 1 +Alpha linolenic acid metabolism 0.7636932707355044 1.059183220655835 0.2895163451839035 1.0 0.6139340279428331 3 Q15067,O15254 2 +Peroxisome 0.3507304379414266 0.9428984977486248 0.345732823385755 1.0 0.6689178539420043 35 P40855,P28288,O96011,P39210,O43808,O75381,O14975,Q9NR77,O15254,Q15067,P56589,O15228,O14678,Q8WVX9,P50542,P33121 16 +Metabolism of xenobiotics by cytochrome p450 0.4858229744745938 0.911994360345806 0.3617716863720797 1.0 0.6817303941120703 10 Q99735,P78417,P11766,O14880,P07099 5 +Ppar signaling pathway 0.4189357848769283 0.8246696446120236 0.4095591699425027 1.0 0.724092708786348 15 O00767,O14975,O15254,Q15067,P23786,O95864,P50416 7 +Phosphatidylinositol signaling system 0.4284194405200275 0.6858076757280744 0.4928343953843763 1.0 0.7704918065375644 12 Q10713,O95674 2 +Other glycan degradation 0.4915649464562767 0.6748757285449991 0.4997547221813998 1.0 0.7704918065375644 7 P04062 1 +Drug metabolism cytochrome p450 0.4322461805818349 0.5737208708628068 0.5661567026911587 1.0 0.8114188982776297 9 P78417,Q99735,O14880,P11766 4 +Arachidonic acid metabolism 0.5470520006772868 0.5386120975077232 0.5901545384161249 1.0 0.8114188982776297 4 P09960 1 +Hypertrophic cardiomyopathy hcm 0.4199230730848168 0.5089705742943194 0.6107728499466516 1.0 0.8114188982776297 9 P16615 1 +Basal cell carcinoma 0.6187793427229895 0.5088698704059597 0.6108434402764178 1.0 0.8114188982776297 3 P04637,P49841 2 +Primary bile acid biosynthesis 0.5447434292865966 0.4211386719750148 0.6736538240146315 1.0 0.850428231734783 2 P51659 1 +Adipocytokine signaling pathway 0.370483330940494 0.3966063933012049 0.6916577372579087 1.0 0.8593534081402804 13 P31751,P14672,O14654,P50416,P33121 5 +Rig i like receptor signaling pathway 0.3969896519284932 0.3917982996255997 0.6952072515292156 1.0 0.8593534081402804 9 Q13526,Q7Z434,Q14258,Q16539,O15111,O43318,O00571,Q13546 8 +Glycerolipid metabolism 0.3567035019726066 0.3182025854942544 0.7503312716768935 1.0 0.8963689017348123 13 Q9HCL2 1 +Inositol phosphate metabolism 0.3692078973730504 0.3091449161596437 0.7572112932905122 1.0 0.8985574013714078 11 Q10713 1 +Starch and sucrose metabolism 0.3427081585339429 0.2821472799136749 0.777830581128899 1.0 0.916912870469828 14 P08236,P52789,P10253 3 +Dilated cardiomyopathy 0.3643710804416916 0.2580853963065994 0.7963410019497394 1.0 0.920446093162686 10 P16615 1 +Glycosaminoglycan degradation 0.4219459806077665 0.2460610394834726 0.8056349819625248 1.0 0.9211735684679792 6 P06865,P08236,P15586 3 +Cytosolic dna sensing pathway 0.3702194357366806 0.2420961345798731 0.8087056732885358 1.0 0.9211735684679792 8 Q9NZI8,O14802,O15160,Q7Z434,O15111,Q9BUI4,Q13546 7 +P53 signaling pathway 0.3486307972560745 0.2372075390152336 0.8124957879183863 1.0 0.9211735684679792 12 Q658P3,O14681 2 +Tyrosine metabolism 0.3491689003927238 0.1684168502615203 0.8662553528485506 1.0 0.9697701434405158 9 P21964 1 +Galactose metabolism 0.3187513831866032 0.1504167918270633 0.880435794025757 1.0 0.9794848208536548 14 P15291,P52789 2 +Folate biosynthesis 0.4164057608014981 0.1219191433965785 0.902963054489399 1.0 0.9919611116762386 4 Q92820,P09417,P00374 3 +Ecm receptor interaction 0.3824087015683318 0.1150961857248236 0.908368883164196 1.0 0.9919611116762386 6 Q08722 1 +Graft versus host disease 0.3825233719447347 0.0515530363548817 0.958884841102319 1.0 1.0 4 P04439 1 +Autoimmune thyroid disease 0.3825233719447347 0.0515530363548817 0.958884841102319 1.0 1.0 4 P04439 1 +Allograft rejection 0.3825233719447347 0.0515530363548817 0.958884841102319 1.0 1.0 4 P04439 1 +Type i diabetes mellitus 0.372470193899173 0.0461873819780505 0.9631608994653604 1.0 1.0 5 P04439 1 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..28b7ce1aacd204aa00e5a1b6ab9d1dc2b536e190 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ACY1", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG5", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "APRT", "AQR", "ARFGAP1", "ARG2", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP8", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAIAP2", "BCAS2", "BCKDHB", "BET1", "BIRC6", "BLVRA", "BNIP1", "BPNT1", "BRCA1", "BUB1B", "BUB3", "BUD23", "BUD31", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2D", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CASK", "CBL", "CBR1", "CCDC6", "CCNB1", "CCNB2", "CD47", "CDC20", "CDC23", "CDC27", "CDC40", "CDC42", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDS2", "CETN2", "CFL1", "CFL2", "CHD8", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP2B", "CHMP5", "CHORDC1", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT2", "CNOT9", "COASY", "COMT", "COX11", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPOX", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CROT", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAG1", "DARS", "DARS2", "DAXX", "DBT", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DEGS1", "DERL1", "DFFA", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH2", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNA2", "DNM1L", "DNM2", "DNMT1", "DOLPP1", "DPAGT1", "DPM1", "DPYSL2", "DPYSL5", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERCC2", "ERCC3", "ERO1A", "EXO1", "EXOC4", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAH", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLCN", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GBE1", "GCAT", "GCDH", "GCLC", "GFPT1", "GGH", "GJA1", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", 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"IMPDH2", "IQGAP1", "IQGAP2", "IRS4", "ISY1", "ISYNA1", "ITGB1", "ITPA", "IVD", "JAK1", "JUP", "KARS", "KDELR1", "KDELR3", "KDSR", "KIDINS220", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARS", "LARS2", "LCLAT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LMO7", "LNPEP", "LPCAT1", "LPGAT1", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LYPLA1", "MALT1", "MAN1A1", "MAN2A1", "MAN2B1", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME2", "MGAT2", "MGST1", "MGST2", "MGST3", "MID1", "MIF", "MMAB", "MOGS", "MPG", "MPHOSPH6", "MPI", "MPST", "MPV17", "MRE11", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTFMT", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTOR", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYL6", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NARS2", "NBN", "NCBP1", "NCKAP1", 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0000000000000000000000000000000000000000..a6fe6bcd77f5f9f1241aecfe6603ef81750ffb33 --- /dev/null +++ b/msigdb_reactome/df_merge.tsv @@ -0,0 +1,50 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transport of small molecules 61 163 4.7753546946500345 1.793907831171282e-06 41.730582524271846 151.96601941747574 1.4265613612661356 0.380396759556163 14.87709311863932 12.598305121005488 1.746958952072276 0.4128488770716938 3.830458021531563e-09 0.1064647583825767 0.0030420207250618 3.9980443747095845e-05 4.264370960178687e-12 +Metabolism of lipids 71 188 4.059344146589323 4.921074065800113e-05 47.21601941747573 182.9902912621359 0.7669400545274999 0.4573741022352977 16.76057659641467 20.451455734561765 1.5920609507025254 0.4091924181498379 1.15617605912043e-13 0.2265411639382284 0.0086726261881225 1.767793644514437e-07 7.786630926900228e-13 +Glycerophospholipid biosynthesis 22 36 3.838136319882408 0.0001239716560275 9.439320388349516 29.58009708737864 1.1800609247564997 0.3081196451067344 4.809346434845489 4.094857299253986 1.3402414818469337 0.3224557628717913 1.2852159182688692e-07 0.3403437958043751 0.0484942526286875 0.0010737250984011 5.713131816783598e-07 +Phospholipid metabolism 28 51 3.644429724807935 0.0002679853447598 12.859223300970871 45.932038834951456 1.017004520648936 0.3949296504793965 6.241466981115118 7.362344677079641 1.3242274243570669 0.3709328103546776 9.466602775957568e-05 0.5310682828592934 0.1855322528907605 0.0132467171015694 0.0001788186084663 +Protein localization 45 79 3.594140601330828 0.0003254640572851 25.97087378640777 74.18203883495146 1.5594110758345356 0.2555609300308859 10.717199959161563 6.26233677332747 2.0947329132902324 0.3569924888492793 6.98000791524177e-10 0.0047018670886403 0.000396243947003 0.0001615199896828 1.3211647988323732e-10 +Sphingolipid metabolism 15 29 3.5528355425688343 0.0003811026393816 11.00242718446602 26.135922330097088 1.1708540815039898 0.1757583754913391 4.192861933829232 2.1968580551223003 2.1941615995620167 0.2567064655985949 7.550588261723106e-09 0.2588687133858448 0.0210654976313926 2.207892594204679e-08 2.3652658127693076e-08 +Slc mediated transmembrane transport 14 23 3.477694944724833 0.0005057451407961 8.672330097087379 21.910194174757283 1.4735742044813558 0.239038892478899 4.348519601656105 3.146764860695784 1.3934177975338422 0.3068823132077037 0.0016084068598747 1.0 0.2496840539684075 0.0352078323408286 0.0010938327023351 +Glycosphingolipid metabolism 9 17 3.322611298608172 0.0008917908694436 7.514563106796117 15.521844660194176 0.6340330218232789 0.1371235236408302 2.3948329397108954 1.2175929202976112 2.2116324239586063 0.2290247571497847 2.513926912022578e-07 1.0 0.2709026461704186 1.0920782304657888e-05 2.11836869740381e-06 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 26 70 3.3008048402760206 0.0009640791783096 20.8373786407767 62.38106796116505 0.8350130317954786 0.3584533980641267 8.974357262450994 5.887120286458052 1.9056004199022172 0.3784220720284639 3.7190713184225375e-10 0.0002235740323544 1.37039732194738e-05 1.6397310502447623e-08 4.846207625713605e-12 +Mitochondrial protein import 24 37 3.1327595407882733 0.0017317124839451 13.468446601941748 34.5873786407767 1.6025718162972953 0.1874419874946837 6.078090089851624 2.2108812815475147 1.8878681708577505 0.2901223460226844 1.1913998245238198e-05 0.0028071579475431 0.0002342837576074 7.846229983304866e-05 3.4526047104435087e-06 +Mitochondrial calcium ion transport 8 17 3.067171142669705 0.0021609509406752 6.502427184466019 16.12135922330097 1.0650233237312683 0.2089377868120644 3.410790121717641 1.246287729205551 1.626144580445205 0.28031724173526 0.0001002866633512 0.0963063052639835 0.0009803497739799 7.429749655930552e-06 2.305883897119265e-07 +Cristae formation 12 21 3.039977861760362 0.0023659553903074 8.475728155339805 19.805825242718445 0.8613288847471563 0.2756396593916832 3.7825471979528897 1.2052333490949263 1.5890526548766304 0.3070386069824295 1.674430390253223e-09 0.0073558029266518 0.0001142112625336 2.56899960600128e-06 7.093363177700493e-11 +Respiratory electron transport 28 59 3.016918462149901 0.0025535848958733 17.473300970873787 52.5752427184466 0.7619430018929745 0.3962973483509951 7.757662405441163 5.39117119769307 1.7039672197087123 0.3858226471737118 1.2569447091700352e-06 0.0001165304651912 4.704358521516937e-05 8.469313599412726e-07 1.0402918101627384e-08 +Asparagine n linked glycosylation 44 130 3.012219291775298 0.0025934517234 27.868932038834952 117.21601941747574 0.3655728203854831 0.6710619346266642 9.979459770251138 10.454219925563558 0.9141135459616458 0.3576788429802088 0.0001746028796617 0.0296336619490533 0.0839989284319177 0.00644077962105 7.677943778987821e-07 +Ion channel transport 16 29 2.854096589659958 0.0043159406968857 9.031553398058252 27.74271844660194 0.8980727715308076 0.3472480807052641 4.2752930421976005 3.4432740668393595 1.4212023690700646 0.3452897078102002 0.0128858063680706 1.0 0.183361016235644 0.0478393395788808 0.0018514914580574 +Diseases associated with n glycosylation of proteins 8 10 2.714786764806091 0.0066318456266551 2.2475728155339807 5.725728155339806 0.3341088995719526 0.3985277581822796 1.5924179977786468 1.7320559095113808 1.1764326310317936 0.3016026507368399 0.0004525401183384 1.0 1.0 0.0086586519898169 7.919881552111625e-07 +Class i peroxisomal membrane protein import 11 12 2.638618634076365 0.0083244568308715 4.300970873786408 9.604368932038836 1.1426576411245968 0.2560233101944223 2.515331441636984 1.9424437465598188 1.2133199793435778 0.2911424942178205 5.351580016797124e-05 1.0 0.1662183776826317 0.0757571260003459 1.310490548470859e-06 +Diseases of glycosylation 13 27 2.6138922774609927 0.008951725552128 6.359223300970874 19.17718446601942 0.13180823173309 0.3045208720095976 2.4657040544471793 2.991113672999948 1.5111068586159069 0.284004628008759 0.0258171487117352 1.0 0.5176995687514377 0.0363101363561639 0.0033976802317393 +Glycosaminoglycan metabolism 8 17 2.5834993941076903 0.0097803638896138 6.563106796116505 14.388349514563108 0.750167459040055 0.1742505874253542 2.387954817808654 2.3973407990867264 1.8682770414846892 0.2409021330213527 0.2792514164559452 1.0 0.4890179724324128 0.0884683246757208 0.2483380072891435 +Transport of inorganic cations anions and amino acids oligopeptides 5 12 2.55862117467358 0.0105088188556961 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 0.0062137664371764 1.0 0.3439334989552355 0.0211003003498726 0.0182027983739356 +The citric acid tca cycle and respiratory electron transport 29 101 2.557538333541079 0.010541593869414 27.99757281553398 94.17961165048544 0.4883573568636233 0.4259472248586306 12.60942373482268 7.020896123249261 1.7895370613076145 0.38969273744301 1.685414872303818e-09 0.0009764000932441 2.0245930019746653e-05 2.908847579194345e-07 1.0611706363506557e-10 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 10 25 2.552191733958208 0.0107047591382494 5.206310679611651 19.733009708737864 0.0173546219692671 0.4747351478662189 2.6010936797167927 3.197629229480199 1.0505158678674285 0.2959489394818763 0.0017114608124302 0.2480154974279715 0.4319828126458854 0.0028705350867404 0.0019208853708131 +Cargo concentration in the er 10 18 2.529416071918889 0.0114252495539137 4.813106796116505 14.480582524271844 0.5034715777808771 0.4707340910089172 2.4168749497181627 1.7521447745979526 1.0073939692365603 0.3173017432503084 0.010479997337549 1.0 0.1975594178204269 0.1053546389470493 0.0041853837586167 +Ire1alpha activates chaperones 5 26 2.521948348346464 0.0116706843515668 6.050970873786408 24.223300970873787 0.9379365742980283 0.4047880585679882 2.6930013625985207 2.1985522104416564 1.0262193137091864 0.3353529084578252 0.0062137664371764 0.1913705796369965 0.0083373177591013 0.0006073886965184 0.0182027983739356 +Pink1 prkn mediated mitophagy 4 9 2.427567617880113 0.0152004530404548 3.2815533980582523 8.473300970873787 1.395617281862234 0.1554977461962819 1.6230588150315317 0.9738153254376878 1.3577427922485954 0.2414588001366878 0.0003373424853699 0.0029386578360865 0.0005152543640852 0.0073447144383531 0.0009780614297071 +Gamma carboxylation hypusine formation and arylsulfatase activation 3 10 2.4152333407327853 0.0157251320993006 3.029126213592233 10.00485436893204 0.7807506256376007 0.3924946945170767 1.4628493985065265 1.556376089571428 0.8873758348558936 0.2775880490120545 0.0234957357441317 1.0 0.2423974925429197 0.0319451393300601 0.0489208457435743 +Synthesis of pa 6 11 2.3775787727498416 0.0174267203526239 2.9635922330097086 8.558252427184467 0.9129149199765416 0.2964837496518883 1.9473992387004595 1.904008254033093 1.1909456358572703 0.2923824193190221 0.0002874289599044 0.1135912525516411 0.2127898194125335 0.0215683584236732 0.0009886385516079 +Mitochondrial biogenesis 14 34 2.3623511803889743 0.0181594308035568 10.572815533980584 33.521844660194176 0.7125383902440768 0.3998427377933914 4.798567629623383 2.9315837025395943 1.2191838320541302 0.3355715376706868 0.000372484260875 0.0627750690965546 0.0086609949738754 0.0043610876134259 4.982931949194838e-05 +Synthesis of very long chain fatty acyl coas 3 8 2.3514710743246665 0.0186993434453199 3.0800970873786406 7.662621359223301 0.2970725454313344 0.3790733377388842 1.7392923430670622 0.9085681268331954 1.2502564772465108 0.3141166423632316 0.0033751577854829 1.0 0.1500965904253892 0.0073447144383531 0.0077153530289291 +Metabolism of steroids 17 42 2.335434682511275 0.0195207243769477 11.16019417475728 45.26699029126213 0.7621248609364072 0.3994790342082778 4.702670999060317 5.049423467032678 1.2014135082145578 0.3371477938402821 0.0001443159713486 0.0875356389619515 0.0748180082788048 0.0001835775213899 3.107724198702484e-05 +Mitophagy 4 13 2.3100919872717407 0.0208830619612678 3.662621359223301 11.783980582524272 1.3564301304992197 0.1917930287367771 1.8155907654273165 1.3363606860118669 1.2723890100166135 0.2636913304405313 0.0018579158445701 0.0058373227860703 0.0014613866465803 0.0193169154759243 0.0050807822676514 +Complex i biogenesis 16 34 2.292027280078764 0.0219040690490091 9.1747572815534 28.546116504854368 0.5440760559261008 0.4236381582634617 4.289696810672699 3.852285850983641 1.2631239118061712 0.3404380044043241 0.0002455927336434 0.0001439027393734 0.0019363115265706 5.349429381762548e-05 1.1149770060160946e-05 +Gpcr ligand binding 3 9 2.263661098472055 0.0235949668615125 3.4611650485436893 9.330097087378642 1.051447004644797 0.2131328881138611 1.5951828582954857 1.3192992367203638 1.3003237502897853 0.2397874119507845 0.0980183809574614 1.0 0.356411341728891 0.0244406528674846 0.1802431538359988 +Stimuli sensing channels 7 9 2.2406024164230405 0.0250518400553745 3.075242718446602 8.648058252427184 0.6737384899082146 0.3285895756392196 1.7754169999219978 1.9694070657894505 1.2463928142905627 0.307032431313504 0.1766066040974135 1.0 0.3050454458143302 0.2332121755087385 0.0345960499792071 +Cholesterol biosynthesis 9 16 2.2391687702265517 0.0251449370145282 5.878640776699029 16.75 1.3996798653689082 0.2350718901934974 2.503362805703168 1.8986773628384943 1.0886216368414 0.270950573691616 1.830425968206786e-06 0.1093006244161378 0.0215793786244467 0.0002291586350063 9.005471748839557e-07 +Processing of smdt1 5 12 2.181073929727515 0.0291779487577399 4.975728155339806 11.155339805825244 0.3833102568885913 0.3649000478471426 2.609615007852169 1.2287595888742628 1.3301610577177632 0.3259664414506655 0.0214626028283106 1.0 1.0 0.0061570039439817 0.0007186517412764 +Intra golgi and retrograde golgi to er traffic 27 91 2.1767699046606466 0.0294977395811935 23.762135922330096 91.83252427184466 0.7836914286379623 0.5449079285432085 8.961715947260837 10.213669235838784 1.1120768516172963 0.4008074869702365 0.0039861855667569 0.5851156872439878 0.0938118896710847 0.0312738129317772 0.0011619981053948 +O linked glycosylation 4 8 2.1763647581639325 0.0295279967977784 1.766990291262136 4.330097087378641 0.8603336668848929 0.3169450005244383 1.1529100664253755 1.1773621125091884 1.0771631098821022 0.279831511700265 0.148521892720825 1.0 0.284754537798848 0.2064377407436189 0.0863207497948327 +Rhoa gtpase cycle 13 45 2.1672062312329525 0.0302191324715512 11.383495145631068 46.157766990291265 0.7285935948010234 0.4866370775942555 5.135874153241841 5.803151375541917 0.959659542192298 0.3649179877597411 0.1413792009388189 0.4778436071549874 0.7245599138381058 0.4057604474152967 0.0589619437017598 +Miscellaneous transport and binding events 4 8 2.1511573434362785 0.0314637826424706 1.9927184466019416 5.745145631067961 0.4222431208164515 0.4979569419811762 1.566470706437162 1.4896408403237755 0.8999895776668405 0.308339259111336 0.0253384839083572 0.0786913117950012 0.1500965904253892 0.3400030327298383 0.045863815130695 +Amino acid transport across the plasma membrane 2 5 2.1182857946141644 0.0341508709569036 1.6019417475728157 3.9466019417475726 0.6798215426479346 0.3497589750262466 1.2195001827124836 1.03907310581091 1.144086667263588 0.2965730694092905 0.0253384839083572 1.0 1.0 0.0621585272883563 0.045863815130695 +Intra golgi traffic 7 13 2.07258215200098 0.0382111834840757 4.424757281553398 13.87135922330097 0.7636302424906817 0.4243971711811651 2.688824171738392 3.845367291797066 0.9598354803720488 0.3140361333882177 0.2160452685634195 1.0 0.0603249601752956 0.0801176308941427 0.1428427753867574 +Formation of atp by chemiosmotic coupling 5 11 2.023613931070916 0.0430098905164464 3.5898058252427183 9.805825242718448 0.4783111855246443 0.2899716869602585 2.2195497140568734 0.9063771094889388 1.382334358445268 0.2713732710506487 6.972612425195793e-06 1.0 0.1253337423142017 0.0041470760753771 2.6394989589163704e-05 +Ion transport by p type atpases 5 12 2.023308946031138 0.0430413051332592 3.7305825242718447 10.33980582524272 0.407323607098393 0.3519804201795568 2.374569281431047 1.6883576098110384 1.2891970822622851 0.3108388098264688 0.1136831966124214 1.0 0.2567853086841904 0.1713585638073601 0.0601547876346515 +Rab geranylgeranylation 8 23 2.0091423958005628 0.0445220346283445 7.703883495145631 20.33009708737864 0.0425571144344789 0.6104117024455028 4.535157640190479 2.923418498732157 0.9174138709438756 0.3132937075649342 0.1509545049231421 1.0 1.0 0.7334839427632852 0.1178873651909481 +Rhod gtpase cycle 8 30 2.002274298174979 0.045255238677482 7.283980582524272 27.854368932038835 0.3944337583042284 0.6115040287236689 3.4591142700991453 2.94828489550352 0.8000693972198841 0.3284465606650851 0.0115527976160783 1.0 1.0 0.1193188519501932 0.0005626054357481 +Transport to the golgi and subsequent modification 30 83 1.980260522371761 0.0476742623015351 20.604368932038835 77.1626213592233 0.4958457957496105 0.6299790557050085 8.044251420264837 7.0373663516482345 0.9638132242129624 0.3700222187340509 0.057486207650749 0.5123592328378659 0.4126058738515607 0.286330031083999 0.0020517129544772 +Selective autophagy 5 30 1.971422618747712 0.0486755559818321 7.315533980582524 31.50728155339806 0.9304065525388932 0.4028226131520862 3.350474746292583 3.101431769008479 1.074438805028982 0.3502038092942861 0.0424352463255198 0.0410390344011431 0.0257953084689971 0.2193268794643932 0.103401142318388 +O linked glycosylation of mucins 3 6 1.967657007875216 0.0491075156346758 1.5946601941747574 3.79126213592233 0.8273892413522829 0.3233813801440507 0.9620319470039822 0.7664831800276773 1.0938082052075415 0.2789554131782936 0.204933269580831 1.0 1.0 0.4160065505344545 0.0871448534539997 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..46dda74bd103923c72792d246909283477fdb87a --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 1396, + "title": "Average number of proteins per term", + "value": 19.40186246418338 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..297cdf7e13bffbb04521c8967d26107e00f4d9d5 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..29b6a526bca0ff68339c94e88a67f24219fb0237 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,325 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport of small molecules 0.522559007031437 4.7753546946500345 1.793907831171282e-06 0.0025011644413574 0.0025042953323165 163 Q9UNS2,Q9Y487,P12236,Q15904,Q9UHQ9,P49721,Q9BPX6,P45880,O95202,Q4KMQ2,Q6PIU2,P40855,Q8WWI5,P08183,Q8N4V1,P09601,P51790,P35610,P30519,Q9HD20,P12235,O15118,Q9Y277,P56589,P28074,P21796,Q70HW3,P20020,Q9H300,P98194,Q9Y4W6,P30825,Q9H936,Q9UBX3,P23634,Q9H2J7,P51798,Q658P3,Q99623,Q9GZP9,P35613,Q9BU23,Q96PU5,Q15043,P63218,O00487,Q8TAD4,Q9C0H2,P16615,Q96QD8,Q93050,Q9H0U3,Q10713,Q8TB61,Q9UBV2,Q9Y6M7,P05141,P05023,Q8WWC4,P43686,Q8WTV0 61 +Metabolism of lipids 0.4566706882805057 4.059344146589323 4.921074065800113e-05 0.0663931719502155 0.0228993979861903 188 P14324,O00767,Q9NTJ5,Q9HCL2,Q15392,Q8WUK0,Q15067,Q8NF37,Q9H7Z7,Q9Y6K0,O15228,Q96N66,P40939,Q14739,Q06136,O95470,P50897,Q8WWI5,Q15800,P48739,P35610,Q8IV08,O14735,Q16850,Q96G23,O15269,Q9P035,P51648,Q53GQ0,Q5T8D3,P17900,Q9BVG9,Q16836,Q9NZ01,O95674,Q8N2A8,O75845,P38435,Q14534,O15254,Q9UG56,Q9NPH0,O43681,Q6Y1H2,Q709F0,P23786,Q9NZJ7,P37268,Q15165,Q92604,Q9H1P3,O43808,Q12770,Q9UBM7,Q8NBJ7,Q8NAN2,P04062,P10619,Q10713,Q16739,P50416,P27544,Q86UL3,P07602,Q9NQZ5,Q16880,Q13510,Q8NBQ5,Q53H12,P04035,P09960 71 +Glycerophospholipid biosynthesis 0.678265487558039 3.838136319882408 0.0001239716560275 0.1589256028873149 0.0374795591124259 36 Q9HCL2,Q8WUK0,Q8NF37,Q9Y6K0,O15228,Q96N66,P40939,Q8WWI5,P48739,Q8IV08,O14735,Q9BVG9,O95674,Q8N2A8,Q9UG56,Q9NPH0,Q92604,Q8NAN2,Q86UL3,Q9NQZ5,P35790,Q53H12 22 +Phospholipid metabolism 0.5980953149788567 3.6444297248079343 0.0002679853447598 0.3121315583816346 0.0374795591124259 51 Q9BZF1,Q9NTJ5,Q9HCL2,Q8WUK0,Q8NF37,O15228,Q9Y6K0,Q96N66,P40939,Q9BTU6,Q8WWI5,P48739,Q8IV08,O14735,Q6UWP7,Q9BVG9,O95674,Q8N2A8,Q9UG56,Q9NPH0,Q92604,Q8NAN2,Q10713,Q8NCE2,Q9NQZ5,Q86UL3,P35790,Q53H12 28 +Protein localization 0.5404429759016612 3.594140601330828 0.0003254640572851 0.3651850735371039 0.0374795591124259 79 O75431,Q99595,P50402,P12236,Q15067,Q9Y512,Q8N4H5,O15228,Q13190,P46379,Q8NBU5,P40855,P39210,P09601,Q9NR77,P12235,Q3ZCQ8,Q9NS69,P56589,P62072,P21796,Q9Y276,P51648,Q5T8D3,Q8TB36,P28288,Q9NX63,O15254,O43681,Q13505,Q9Y5J6,O96011,O43808,O75381,O96008,O14925,O14975,Q9Y3D6,Q9UJS0,Q10713,O95169,O43615,Q96DA6,Q15388,O75746 45 +Sphingolipid metabolism 0.7068182307431328 3.5528355425688343 0.0003811026393816 0.4126419547801463 0.0374795591124259 29 Q8NBJ7,P04062,P10619,Q16739,Q96G23,P27544,O43681,P07602,Q16880,P51648,Q9NZJ7,Q13510,P17900,Q06136,O95470 15 +Slc mediated transmembrane transport 0.7553134911095359 3.477694944724833 0.0005057451407961 0.5064834130912256 0.0374795591124259 23 Q8WWI5,Q9UBX3,Q9H2J7,P12236,Q8TB61,P05141,P35613,P12235,Q9Y6M7,Q15043,Q70HW3,Q8TAD4,P30825,Q96QD8 14 +Glycosphingolipid metabolism 0.7762098203164106 3.322611298608172 0.0008917908694436 0.7122017304071875 0.0374795591124259 17 Q8NBJ7,P04062,P10619,Q16739,P07602,O43681,Q9NZJ7,Q13510,P17900 9 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.5318067321248132 3.3008048402760206 0.0009640791783096 0.7398517726846381 0.0374795591124259 70 O95298,O96000,Q9Y6M9,O14949,Q9Y6N1,O43676,P03886,Q86Y39,Q9NPL8,P00403,Q9P0J0,P24539,Q8N8Q8,Q9Y375,O75964,P56385,P13073,P03915,P00846,P21912,P56134,O75306,P36542,Q9UDW1,Q9NX14,O75880 26 +Mitochondrial protein import 0.5853360482523016 3.1327595407882733 0.0017317124839451 0.911039802580584 0.0447679745849512 37 Q9Y5J9,O75431,Q99595,P12236,Q9Y512,Q8N4H5,P12235,Q3ZCQ8,Q9NS69,P62072,P21796,Q9Y276,Q9NX63,Q13505,Q9Y5J6,O96008,O14925,Q9UJS0,Q10713,O95169,O43615,Q96DA6,Q15388,O75746 24 +Mitochondrial calcium ion transport 0.732036324929813 3.0671711426697055 0.0021609509406752 0.9511964231816052 0.0486562502126234 17 Q10713,Q9BPX6,Q9Y277,P45880,O95202,Q8WWC4,P21796,Q9H300 8 +Cristae formation 0.7028594160771036 3.039977861760362 0.0023659553903074 0.9633663156595182 0.049918028010082 21 Q9BUR5,Q5XKP0,P00846,O75964,Q6UXV4,P56385,P56134,Q9Y512,P24539,P36542,Q13505,Q9NVH1 12 +Respiratory electron transport 0.5210884371863829 3.016918462149901 0.0025535848958733 0.971826227681684 0.0516638335454949 59 O95298,O96000,Q9Y6M9,O14949,Q9Y6N1,O95139,O43676,P03886,Q86Y39,Q9NPL8,Q16134,P00403,Q9P0J0,Q8N8Q8,P20674,Q9BQ95,O00483,Q9Y375,P13073,P03915,P21912,O75306,O43819,O95169,Q9UDW1,Q9NX14,P51970,O75880 28 +Asparagine n linked glycosylation 0.4272931594575038 3.012219291775298 0.0025934517234 0.973355205640471 0.0517208372266646 130 Q9UJW0,Q9H3H5,P24390,Q10469,Q9BV10,O60858,O15020,Q11206,Q9BVK6,P04843,Q13190,Q9Y3B3,O75352,Q96AA3,O75935,P46977,Q86YN1,O75340,Q14789,Q9H0U4,P49755,Q86SQ9,O14653,Q96PC5,Q16706,Q9BT22,P62820,Q9GZP9,Q9UKV5,Q15363,Q13561,Q2TAA5,Q9Y6Y8,O43731,Q9H0U3,P10619,P27824,P15291,Q9UBV2,P49257,O95249,Q5JRA6,P53634,O15498 44 +Ion channel transport 0.6089015645088773 2.854096589659958 0.0043159406968857 0.997613894239372 0.075313165160657 29 Q93050,P23634,P51798,P51790,Q9Y487,Q15904,P27105,Q9HD20,P05023,Q96PU5,P20020,Q12797,Q4KMQ2,P98194,Q9C0H2,P16615 16 +Diseases associated with n glycosylation of proteins 0.8245353591820264 2.714786764806091 0.0066318456266551 0.9999075545578084 0.0952018144805679 10 Q96AA3,Q9H3H5,Q9BT22,P15291,Q10469,Q9BV10,O75340,Q2TAA5 8 +Class i peroxisomal membrane protein import 0.7705586942875059 2.638618634076365 0.0083244568308715 0.9999914500136152 0.1066141443660249 12 Q8NBU5,P40855,P28288,O43808,O75381,O96011,Q9NR77,P56589,Q8TB36,P51648,Q5T8D3 11 +Diseases of glycosylation 0.5932595349292293 2.6138922774609927 0.008951725552128 0.999996465285526 0.11058945903337 27 O43505,Q96AA3,Q9H3H5,Q86SQ9,Q9BT22,Q8NCH0,P10619,Q10469,Q9BV10,P15291,O75340,Q2TAA5,O75352 13 +Glycosaminoglycan metabolism 0.6521319616545957 2.5834993941076903 0.0097803638896138 0.9999989004330092 0.1187251129556608 17 O43505,P15586,Q8NCH0,P15291,Q8TB61,Q11206,P08236,Q7LGA3 8 +Transport of inorganic cations anions and amino acids oligopeptides 0.7551678398843671 2.5586211746735796 0.0105088188556961 0.9999996064033866 0.1236644121151424 12 Q9UBX3,Q9H2J7,Q70HW3,P30825,Q96QD8 5 +The citric acid tca cycle and respiratory electron transport 0.4063857129849509 2.557538333541079 0.010541593869414 0.9999996241891532 0.1236644121151424 101 O95298,O96000,Q9Y6M9,O14949,Q9Y6N1,O43676,Q13423,P03886,Q86Y39,Q9NPL8,P00403,Q9P0J0,P24539,Q8N8Q8,P21796,Q9Y375,O75964,P56385,P13073,P35613,P03915,P00846,P21912,P56134,O75306,P36542,Q9UDW1,Q9NX14,O75880 29 +Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.5996541070233374 2.5521917339582076 0.0107047591382494 0.9999997014726604 0.1245320313083016 25 Q96AA3,Q9H3H5,Q9BT22,P10619,Q9BV10,Q86YN1,Q11206,O75340,Q2TAA5,O75352 10 +Cargo concentration in the er 0.6419425548847676 2.529416071918889 0.0114252495539137 0.999999892035432 0.1296719380265336 18 P49755,Q96PC5,O14653,Q5JRA6,O75396,Q15363,Q9Y6B6,P53634,Q13190,P49257 10 +Ire1alpha activates chaperones 0.5882630650988169 2.5219483483464633 0.0116706843515668 0.9999999236618168 0.1313893173773167 26 O14773,O14653,P43307,O95070,Q9Y5M8 5 +Pink1 prkn mediated mitophagy 0.782448985527146 2.427567617880113 0.0152004530404548 0.9999999994828878 0.1560281797387861 9 Q9NS69,Q8N4H5,P21796,O96008 4 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.763657617631736 2.4152333407327853 0.0157251320993006 0.9999999997542526 0.1602356526322893 10 O60725,P38435,Q8NBJ7 3 +Synthesis of pa 0.7397709573245999 2.3775787727498416 0.0174267203526239 0.9999999999780482 0.1701237874983427 11 Q8N2A8,Q9HCL2,Q86UL3,Q9NPH0,Q8NF37,O15228 6 +Mitochondrial biogenesis 0.5078012370714232 2.3623511803889743 0.0181594308035568 0.999999999992252 0.1760455930678151 34 Q9BUR5,Q5XKP0,P00846,O75964,Q6UXV4,P56385,P56134,Q9Y512,P00367,P24539,P36542,Q16891,Q13505,Q9NVH1 14 +Synthesis of very long chain fatty acyl coas 0.7825136200327011 2.3514710743246665 0.0186993434453199 0.9999999999964048 0.176380293578829 8 Q9P035,Q9NZ01,Q53GQ0 3 +Metabolism of steroids 0.4802505237150723 2.335434682511275 0.0195207243769477 0.999999999998883 0.1828921559075103 42 Q15800,Q12770,Q9UBM7,O00767,O75845,P38435,P04062,P37268,Q9HCL2,Q15392,Q14534,Q16850,Q53GQ0,Q8NBQ5,P04035,Q14739,Q9H1P3 17 +Mitophagy 0.6893746727566857 2.3100919872717407 0.0208830619612678 0.9999999999998396 0.1943516966528664 13 Q9NS69,Q8N4H5,P21796,O96008 4 +Complex i biogenesis 0.4997267402545852 2.292027280078764 0.0219040690490091 0.9999999999999626 0.2011715815290572 34 Q9NPL8,Q9Y375,O95298,P51970,O96000,O75306,Q9Y6M9,Q9P0J0,P03915,O95169,O95139,O43676,Q9NX14,P03886,Q86Y39,Q9BQ95 16 +Gpcr ligand binding 0.7491651778742864 2.263661098472055 0.0235949668615125 0.9999999999999968 0.2045874145259098 9 P07602,Q9NZJ7,P63218 3 +Stimuli sensing channels 0.7445352955628586 2.2406024164230405 0.0250518400553745 0.9999999999999996 0.2101936052232421 9 P51798,P51790,P27105,Q96PU5,Q12797,Q4KMQ2,Q9C0H2 7 +Cholesterol biosynthesis 0.6184135423979031 2.2391687702265513 0.0251449370145282 0.9999999999999996 0.2101936052232421 16 Q15800,Q9UBM7,O75845,Q14739,Q14534,Q15392,Q16850,P04035,P37268 9 +Processing of smdt1 0.6845345487825398 2.181073929727515 0.0291779487577399 1.0 0.2328624848853624 12 Q99623,Q10713,Q9BPX6,Q8WWC4,Q9H300 5 +Intra golgi and retrograde golgi to er traffic 0.3978626709427129 2.1767699046606466 0.0294977395811935 1.0 0.2328874775689189 91 Q9UJW0,P24390,Q8TBA6,Q9BVK6,O60499,Q13190,Q9Y3B3,Q96JB2,O75935,Q8N2H4,Q9H0U4,P49755,O14653,Q16706,P62820,Q15363,Q13561,O00461,Q9P2W9,Q07866,Q9H0B6,O43731,O15498,O95249,Q12981,O15260,Q10472 27 +O linked glycosylation 0.7463970944448912 2.1763647581639325 0.0295279967977784 1.0 0.2328874775689189 8 Q11206,Q8N4A0,Q10472,Q9H5K3 4 +Rhoa gtpase cycle 0.4544790925983714 2.1672062312329525 0.0302191324715512 1.0 0.2369994883723909 45 P41440,Q14155,Q96CS3,P51572,O15173,Q15904,P30519,P49257,Q8TAA9,P42167,Q5T8D3,Q14739,O15498 13 +Miscellaneous transport and binding events 0.741259450600351 2.1511573434362785 0.0314637826424706 1.0 0.2453823495468659 8 Q9H0U3,Q9UNS2,Q9HD23,Q8N4V1 4 +Vitamin d calciferol metabolism 0.9383604505632082 2.1201031821184317 0.0339973446704449 1.0 0.2591011731295513 2 P04062 1 +Amino acid transport across the plasma membrane 0.8874964169749165 2.1182857946141644 0.0341508709569036 1.0 0.2591011731295513 5 P30825,Q96QD8 2 +Intra golgi traffic 0.6473014053580325 2.07258215200098 0.0382111834840757 1.0 0.2735528827885625 13 O14653,Q16706,Q8TBA6,O95249,O00461,Q13190,O15498 7 +Maturation of protein 3a 0.9208385481852336 2.0434131918345786 0.041011552677499 1.0 0.2862606376889431 2 Q11206 1 +Heme degradation 0.9034302198413314 2.028169816046566 0.0425429193714244 1.0 0.2940094823886558 4 P09601 1 +Formation of atp by chemiosmotic coupling 0.6727865045664451 2.023613931070916 0.0430098905164464 1.0 0.2945375586570091 11 P00846,O75964,P56385,P24539,P36542 5 +Ion transport by p type atpases 0.6559494723134037 2.023308946031138 0.0430413051332592 1.0 0.2945375586570091 12 Q9HD20,P05023,P20020,P98194,P16615 5 +Rab geranylgeranylation 0.5369243336320648 2.0091423958005628 0.0445220346283445 1.0 0.3017124288406264 23 Q969Q5,P61026,P53611,Q9H0U4,P62820,Q6IQ22,P61019,O14966 8 +Rhod gtpase cycle 0.492842142243692 2.002274298174979 0.045255238677482 1.0 0.3046315424450436 30 P50402,O15173,P49257,Q9Y6M7,Q8TAA9,P42167,Q86Y07,Q14739 8 +Abacavir transport and metabolism 0.9083229036295368 1.9883682484129064 0.0467709777504192 1.0 0.3094421087184137 2 P49902 1 +Transport to the golgi and subsequent modification 0.3948396387639059 1.980260522371761 0.0476742623015351 1.0 0.3109965895931919 83 Q9UJW0,P24390,Q10469,O15020,Q11206,Q9BVK6,Q13190,Q9Y3B3,Q96JB2,O75935,Q14789,O15027,P49755,Q9H0U4,O14653,Q96PC5,Q16706,P62820,O75396,Q15363,Q13561,Q9Y6B6,Q9Y6Y8,O43731,P15291,P49257,O95249,Q5JRA6,P53634,O15498 30 +Selective autophagy 0.4891593484906355 1.9714226187477115 0.0486755559818321 1.0 0.3158030459823482 30 O96008,Q9NS69,Q8N4H5,P21796,P08670 5 +O linked glycosylation of mucins 0.8060749348867788 1.9676570078752156 0.0491075156346758 1.0 0.3158030459823482 6 Q11206,Q8N4A0,Q10472 3 +Incretin synthesis secretion and inactivation 0.8864975841472884 1.9587671511222065 0.0501400622031433 1.0 0.3158030459823482 4 P67812 1 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.8864975841472884 1.9587671511222065 0.0501400622031433 1.0 0.3158030459823482 4 P67812 1 +Copi mediated anterograde transport 0.4232582477268518 1.9549740981374744 0.0505861275832129 1.0 0.3158030459823482 53 P49755,Q9UJW0,O43731,O14653,P24390,O75935,P62820,O15020,Q9BVK6,Q15363,Q13561,O95249,Q13190,Q9Y3B3,Q14789,O15498,Q9H0U4 17 +Peptide hormone metabolism 0.6259832019232032 1.9496875234023132 0.0512133742938625 1.0 0.3158030459823482 13 P67812,Q8TAD4 2 +Pre notch processing in golgi 0.847478860006252 1.9492436654268304 0.0512663326173361 1.0 0.3158030459823482 5 Q11206,Q15363,Q9UBV2,P16615 4 +Metabolism of porphyrins 0.6718643584672379 1.9419762164562544 0.0521399795848369 1.0 0.3158030459823482 10 P09601,Q7KZN9,P30519,P22830 4 +The activation of arylsulfatases 0.894868585732164 1.9289590016693672 0.0537359521321803 1.0 0.3158030459823482 2 Q8NBJ7 1 +Metal ion slc transporters 0.8939299123904989 1.9248053636735032 0.0542537127353097 1.0 0.3158030459823482 2 Q8TAD4 1 +Zinc transporters 0.8939299123904989 1.9248053636735032 0.0542537127353097 1.0 0.3158030459823482 2 Q8TAD4 1 +Transport of vitamins nucleosides and related molecules 0.796015502899069 1.922883854797298 0.0544946378245334 1.0 0.3158030459823482 6 P12236,Q8TB61,P12235 3 +Sphingolipid de novo biosynthesis 0.6374575868654637 1.919713077284927 0.0548941514959084 1.0 0.3158030459823482 12 P27544,Q96G23,P51648,Q06136,O95470 5 +Unfolded protein response upr 0.4347997951123689 1.918385045693198 0.0550622058247363 1.0 0.3158030459823482 43 O14773,O14653,P43307,O95070,Q9Y5M8 5 +Acyl chain remodelling of pg 0.8914267834793579 1.913723516864133 0.0556554925566172 1.0 0.3158030459823482 2 Q8NF37 1 +Transport of bile salts and organic acids metal ions and amine compounds 0.8302536799248295 1.8756214327181513 0.0607072812390692 1.0 0.3297562825281736 5 Q15043,Q9H2J7,P35613,Q8TAD4 4 +Initiation of nuclear envelope ne reformation 0.5368809167289286 1.863981330177006 0.0623243262040495 1.0 0.3308405736608439 19 P50402,Q86XL3,P42167,Q8IXJ6,Q14739 5 +Arachidonate production from dag 0.8726533166458241 1.8303648647578157 0.0671953979026078 1.0 0.347425094340891 2 Q8NCG7 1 +Synthesis of pc 0.6745746965257751 1.8172634471309088 0.0691767840756654 1.0 0.351166511162287 8 Q9NQZ5,Q8NF37,Q8WWI5,Q9Y6K0 4 +Nuclear envelope ne reassembly 0.4113807807200746 1.810019562738025 0.0702927535148507 1.0 0.3555387098069987 48 P50402,Q8NFH5,Q86XL3,P42167,Q86Y07,Q9BTX1,Q8IXJ6,Q7Z3B4,Q14739 9 +Synaptic adhesion like molecules 0.8121841447954417 1.797857885261562 0.0721995314958952 1.0 0.3612564371622569 5 O95197 1 +Rac2 gtpase cycle 0.4348712943776125 1.7952826202806211 0.0726086826425032 1.0 0.3620061463176231 37 P50402,O15173,Q86XL3,P49257,Q9Y512,Q8TAA9,P42167,Q13505,Q14739 9 +Peptide ligand binding receptors 0.757592920066642 1.7500549982813236 0.0801088239758209 1.0 0.3834937710288165 6 P07602,Q9NZJ7 2 +Class a 1 rhodopsin like receptors 0.757592920066642 1.7500549982813236 0.0801088239758209 1.0 0.3834937710288165 6 P07602,Q9NZJ7 2 +Synthesis of pg 0.8359423919849667 1.7490125073040743 0.0802888574611717 1.0 0.3834937710288165 4 Q8IV08,Q8N2A8,O95674 3 +N glycan antennae elongation 0.8466833541927561 1.7144049239101704 0.086454384854151 1.0 0.3962677933543367 2 Q11206 1 +Post translational modification synthesis of gpi anchored proteins 0.6513061506954071 1.6978959502443929 0.0895274017535086 1.0 0.3987682440716465 8 Q5H8A4,O43292,Q9H490 3 +Ras processing 0.7777377820610583 1.6481968188679568 0.0993122894187834 1.0 0.4239754006991489 5 O60725,P49356 2 +Rnd1 gtpase cycle 0.5090856730655493 1.6403769539399804 0.1009268140826264 1.0 0.4282487308794729 17 O43396,P51648 2 +Organic anion transporters 0.8197747183980197 1.5936079289326035 0.1110238774755729 1.0 0.4544372932688971 2 Q9UBX3 1 +Sialic acid metabolism 0.7230207222925271 1.592240723098443 0.111330626287939 1.0 0.4544372932688971 6 Q11206 1 +Er to golgi anterograde transport 0.3714205462466234 1.5901193991520004 0.1118078940201561 1.0 0.4550548689566703 77 Q9UJW0,P24390,O15020,Q9BVK6,Q13190,Q9Y3B3,Q96JB2,O75935,Q14789,O15027,P49755,Q9H0U4,O14653,Q96PC5,P62820,O75396,Q15363,Q13561,Q9Y6B6,Q9Y6Y8,O43731,P49257,O95249,Q5JRA6,P53634,O15498 26 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8935050588819073 1.5830055296403742 0.1134202040482015 1.0 0.4566508947398971 3 P67812 1 +Synthesis secretion and deacylation of ghrelin 0.8935050588819073 1.5830055296403742 0.1134202040482015 1.0 0.4566508947398971 3 P67812 1 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.7960719129734372 1.5811855870537364 0.1138356098635273 1.0 0.4566508947398971 4 P12236,P12235 2 +Copi dependent golgi to er retrograde traffic 0.3889162266854932 1.5711198580247818 0.1161548107931169 1.0 0.4598901629542497 50 P49755,Q9H0B6,P24390,P62820,Q9BVK6,Q12981,Q9P2W9,Q9Y3B3,O15260,Q9H0U4 10 +Peroxisomal lipid metabolism 0.5548976647298722 1.5278328740291762 0.1265540379046827 1.0 0.4753485624952546 13 Q15067,Q5T8D3,P51648,O15254 4 +N glycan antennae elongation in the medial trans golgi 0.7472630775243936 1.514405272307911 0.1299230828937485 1.0 0.4836603299191279 5 Q11206,P15291,Q10469 3 +Er quality control compartment erqc 0.746895953736238 1.5127865241086964 0.1303338929386326 1.0 0.4838992408040721 5 Q9GZP9,Q9UBV2,O60858 3 +Hs gag biosynthesis 0.7984981226533377 1.4977667704069175 0.1341938571108629 1.0 0.4930369218724056 2 Q7LGA3 1 +Bmal1 clock npas2 activates circadian gene expression 0.7981852315394414 1.4963558952419191 0.1345609364135782 1.0 0.4930369218724056 2 P43490 1 +Rora activates gene expression 0.798185231539422 1.496355895241833 0.1345609364136006 1.0 0.4930369218724056 2 P50416 1 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.6068410772297694 1.4660250196277655 0.1426414708579477 1.0 0.5145413264023129 8 Q96DE5,Q9UJX5,Q12834,Q9UJX2,P30260 5 +Heparan sulfate heparin hs gag metabolism 0.6918549770374816 1.448342524761736 0.1475212802933667 1.0 0.5244965876716763 6 P08236,Q7LGA3 2 +Ptk6 regulates proteins involved in rna processing 0.7862953692115116 1.442723693412671 0.1490983220610857 1.0 0.5251930080231655 2 Q07666 1 +Small interfering rna sirna biogenesis 0.785982478097619 1.4413119500097855 0.1494965727638675 1.0 0.5251930080231655 2 Q15631 1 +Attachment of gpi anchor to upar 0.726468321603049 1.4224891795776329 0.1548842904952669 1.0 0.5340143114711955 5 Q92643,O43292,Q9H490 3 +Maturation of sars cov 2 spike protein 0.5371307901134339 1.4197158601282602 0.1556904188888084 1.0 0.5340143114711955 13 Q9H0U3,Q16706,P27824,Q10469,P46977,Q11206 6 +Organelle biogenesis and maintenance 0.3419670917423658 1.4102113460720396 0.158477286568871 1.0 0.5402148060797115 91 O75431,Q9Y512,Q16891,Q9BUR5,Q5XKP0,Q6UXV4,O75935,P24539,Q9NVH1,Q7Z4L5,O75964,P56385,P00367,A0AVF1,Q13505,P00846,P56134,Q10713,P36542,Q9H6D7 20 +Interleukin 4 and interleukin 13 signaling 0.5333628993639586 1.396666296220357 0.1625139438882663 1.0 0.5474666801775603 13 P09601,Q07820,P08670 3 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.5685148141668638 1.378691515756069 0.1679898864890612 1.0 0.5545233879990928 10 P50402,P09601,O43681,P51648,Q13190 5 +Keratan sulfate biosynthesis 0.8403755868544613 1.3684995147412429 0.1711557737897153 1.0 0.559012396348886 3 Q11206,P15291 2 +Copii mediated vesicle transport 0.3932899991574997 1.3637531779495868 0.1726452611126518 1.0 0.5604948477052606 35 P49755,O14653,P62820,O95486,Q9HCU5,P49257,O75396,O15027,Q15363,Q9Y6B6,Q9Y6Y8,Q13190,P55735,P53634,O15498,Q9H0U4 16 +Cytochrome p450 arranged by substrate type 0.8388215531236444 1.362212665423115 0.1731307798880133 1.0 0.5607669807973702 3 Q16850 1 +Effects of pip2 hydrolysis 0.8375558084269488 1.3570919597749402 0.1747519928652519 1.0 0.5634036536718052 3 Q8NCG7 1 +Noncanonical activation of notch3 0.766583229036292 1.3537819441855437 0.1758059557790146 1.0 0.5654956549942497 2 P67809 1 +Cytosolic sulfonation of small molecules 0.7418011315953494 1.3502024133112127 0.1769510643047085 1.0 0.5655968811180101 4 Q9NX62 1 +Inflammasomes 0.7411583509765152 1.3474547715430665 0.1778338106574706 1.0 0.5655968811180101 4 P09601 1 +The nlrp3 inflammasome 0.7411583509765152 1.3474547715430665 0.1778338106574706 1.0 0.5655968811180101 4 P09601 1 +Signaling by retinoic acid 0.5611504508649927 1.3374988719780316 0.1810598502374369 1.0 0.5692782678636532 10 Q15118,P50416,Q9HBH5,Q8NBN7 4 +Keratan sulfate keratin metabolism 0.623555399284295 1.3315165186867688 0.1830191133408552 1.0 0.5741453533119862 7 O43505,P15291,Q11206 3 +Platelet calcium homeostasis 0.7049447881870196 1.3269425454264707 0.1845276890865501 1.0 0.5764291549797554 5 P20020,P23634,P16615 3 +Linoleic acid la metabolism 0.7603254067584444 1.3255588605700634 0.1849858606238756 1.0 0.5764291549797554 2 O95864 1 +Synthesis of pe 0.8282212545797283 1.319327135138379 0.1870597699044558 1.0 0.5803009750813785 3 Q9UG56 1 +Translation of sars cov 2 structural proteins 0.4562986412548604 1.3104709370349703 0.1900365697810397 1.0 0.5807278174352807 20 Q9H0U3,Q16706,P27824,Q10469,P46977,Q11206,Q10472,P49841 8 +Rac3 gtpase cycle 0.3865824814743697 1.3102557801352377 0.1901093213237272 1.0 0.5807278174352807 36 P50402,O15173,P49257,Q8TAA9,P42167,Q86Y07,Q14739 7 +G protein activation 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.5843537699929758 2 P63218 1 +Inwardly rectifying k channels 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.5843537699929758 2 P63218 1 +Potassium channels 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.5843537699929758 2 P63218 1 +Presynaptic function of kainate receptors 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.5843537699929758 2 P63218 1 +Glucagon type ligand receptors 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.5843537699929758 2 P63218 1 +Prostacyclin signalling through prostacyclin receptor 0.7534418022528412 1.294530496005043 0.1954822425406301 1.0 0.5843537699929758 2 P63218 1 +Synthesis of substrates in n glycan biosythesis 0.4568490458707757 1.2709489033969188 0.2037468271098859 1.0 0.6026071411978828 18 Q11206,Q86YN1 2 +Ra biosynthesis pathway 0.8140845070422507 1.2621508204343312 0.2068945212699589 1.0 0.6067746884303836 3 Q9HBH5,Q8NBN7 2 +Cd28 dependent pi3k akt signaling 0.7443679599499403 1.2536687531654944 0.2099624298309887 1.0 0.6081842181646604 2 P31751 1 +Rhog gtpase cycle 0.3767143061739104 1.2525386963831728 0.2103736370892766 1.0 0.6081842181646604 39 P50402,O15173,Q86XL3,P49257,Q8TAA9,P42167,O95202,Q86Y07,Q14739,O15498 10 +Iron uptake and transport 0.4532177905942752 1.2446762601356878 0.2132507757607249 1.0 0.6117432071421388 18 Q93050,P09601,Q9Y487,Q658P3,P30519 5 +Transcriptional regulation by ventx 0.5415215403299316 1.2272000419587632 0.2197474136761965 1.0 0.6202961491037339 10 P04637,Q96DE5,Q9UJX5,Q9UJX2,P30260 5 +Reduction of cytosolic ca levels 0.7108840582149903 1.217911740814382 0.2232575140671042 1.0 0.6241422989168013 4 P20020,P16615 2 +Post translational protein modification 0.2825812013395202 1.1939721929953693 0.2324888455398381 1.0 0.6326700078714522 409 O43505,P24390,O60858,O15020,P45880,Q6IQ22,Q13190,Q7Z3B4,P61019,O75352,Q70CQ2,P46977,Q86YN1,Q7Z434,Q9Y277,P21796,Q9H5K3,Q86SQ9,O14653,Q16706,Q969V5,Q14166,O60725,Q13561,Q9Y6Y8,Q02818,P04439,O43731,Q92905,Q86VX2,P28072,Q5JRA6,Q13636,P53634,Q969Q5,Q9H3H5,Q9UJW0,Q11206,P04843,P61978,Q96JB2,Q9UPU5,Q5H8A4,Q13546,Q96AA3,Q12834,Q9NZL9,Q96GG9,O94952,Q9H490,P38435,Q96PC5,Q9BT22,Q8NBJ7,P10619,Q9UBV2,O95249,Q10472,Q9UNS2,O43292,Q9BV10,P49721,Q07065,Q9BVK6,Q9Y3B3,O75340,P28074,Q9BTX1,O14966,P49755,Q7L5N1,P62820,Q9GZP9,O43681,P61026,O75381,Q9H0U3,P49257,Q8NFH5,Q8N4A0,Q10469,Q9BTY2,O75935,P51784,Q14789,O15504,Q9H0U4,Q12769,O43852,Q9UKV5,Q15363,Q92643,Q2TAA5,O00487,P53611,P27824,P15291,P43686,O15498 99 +Cardiac conduction 0.4869624048920741 1.19049412472607 0.2338522378665253 1.0 0.6326700078714522 14 Q13586,P23634,P05023,P20020,P16615 5 +Ion homeostasis 0.4869624048920741 1.19049412472607 0.2338522378665253 1.0 0.6326700078714522 14 Q13586,P23634,P05023,P20020,P16615 5 +Platelet homeostasis 0.4701787355129432 1.1677698978444415 0.2428995934530391 1.0 0.6490657702353912 15 Q13586,P23634,Q16537,Q99487,P63218,P20020,P16615 7 +Basigin interactions 0.6598327696483877 1.1259957237729867 0.2601673293557962 1.0 0.6639736595625074 5 P35613,P54709 2 +Abc transporters in lipid homeostasis 0.7799687010954477 1.1245098131052005 0.2607968098601683 1.0 0.6643655959211586 3 P40855,P56589 2 +Wax and plasmalogen biosynthesis 0.6883529004764092 1.1215218486730207 0.262065796714928 1.0 0.6651706403891627 4 O15228,Q6IAN0 2 +Tp53 regulates metabolic genes 0.3685041275851956 1.1197456220282025 0.2628221777223658 1.0 0.6655711824452754 35 P31751,P00403,P13073,O43819,Q9Y6N1,Q8N8Q8,O75880 7 +Translation of sars cov 1 structural proteins 0.541201635390007 1.1166954297646248 0.2641245726192691 1.0 0.6655711824452754 8 Q11206,P27824,Q10472 3 +Fatty acyl coa biosynthesis 0.4624881951436578 1.1164283366522132 0.264238829672371 1.0 0.6655711824452754 15 P50897,O00767,Q9P035,Q53GQ0,Q9NZ01 5 +Bicarbonate transporters 0.7124530663329407 1.1105670460706571 0.2667547539737471 1.0 0.6655711824452754 2 Q9Y6M7 1 +Transport of connexons to the plasma membrane 0.685660613650598 1.110017918289364 0.266991305278903 1.0 0.6655711824452754 4 Q9BUF5,Q13885,P17302 3 +Gap junction assembly 0.685660613650598 1.110017918289364 0.266991305278903 1.0 0.6655711824452754 4 Q9BUF5,Q13885,P17302 3 +Carboxyterminal post translational modifications of tubulin 0.6856606136505959 1.1100179182893546 0.266991305278907 1.0 0.6655711824452754 4 Q9BUF5,Q13885,Q14166 3 +Alpha oxidation of phytanate 0.6509688769412 1.0865194644510252 0.2772492341663208 1.0 0.6756960843156313 5 O43808,P51648 2 +Fatty acid metabolism 0.3440925008235841 1.0774810257150766 0.2812654230600799 1.0 0.6793192570793627 57 P50897,O00767,Q15165,O15254,Q15067,Q9P035,Q6Y1H2,Q709F0,Q9H7Z7,Q53GQ0,Q5T8D3,P51648,P23786,P40939,Q16836,Q9NZ01,P09960 17 +Response to elevated platelet cytosolic ca2 0.3775846700064781 1.075908297262368 0.2819682707595976 1.0 0.6798405975481836 32 Q8NBM8,O43852,Q6UXV4,P13473,Q96JJ7,Q9UHQ9,P07602,Q8NBX0,Q9NZJ7,Q9Y6I9,Q92520,O94919 12 +Vitamin c ascorbate metabolism 0.7033792240300522 1.0701459171778451 0.2845536336180108 1.0 0.6825375816679434 2 P78417 1 +Chylomicron assembly 0.7024405506883544 1.0659731942800803 0.2864357595220261 1.0 0.6858736197131192 2 Q9Y6B6 1 +Apc cdc20 mediated degradation of nek2a 0.512487285020298 1.0630697127637576 0.2877503382711688 1.0 0.6866657644898319 10 Q96DE5,Q9UJX5,Q12834,Q9UJX2,P30260,O60566 6 +Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.512487285020298 1.0630697127637576 0.2877503382711688 1.0 0.6866657644898319 10 Q96DE5,Q9UJX5,Q12834,Q9UJX2,P30260,O60566 6 +Endosomal vacuolar pathway 0.6732021094914432 1.0568501199340534 0.2905799960480573 1.0 0.6887091247590628 4 Q9UIQ6,P04439 2 +Sars cov 2 infection 0.3953353182740352 1.0325504398215832 0.3018143313911188 1.0 0.6998883830930263 27 Q9H0U3,Q16706,P27824,Q10469,P46977,Q11206,Q10472,P49841 8 +Rnd2 gtpase cycle 0.4221874152588764 1.0186859559203756 0.3083520820756003 1.0 0.7079926095025295 18 O43396,P51648,Q07065 3 +Mucopolysaccharidoses 0.6613093887309693 1.006232974563427 0.3143035136159282 1.0 0.7166575333335727 4 P08236,P15586 2 +Pexophagy 0.6880475594493052 1.0022293469535504 0.3162328370583664 1.0 0.7166575333335727 2 P50542 1 +Nrif signals cell death from the nucleus 0.688047559449305 1.0022293469535486 0.3162328370583673 1.0 0.7166575333335727 2 Q92542 1 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4914763271954201 0.9977596540549551 0.3183959186122405 1.0 0.7192244375124397 11 P09601 1 +Slc transporter disorders 0.3728301840456913 0.9935782284138642 0.3204282479081062 1.0 0.7203185733972887 31 Q8NFH5,P35613,Q9BTX1,Q7Z3B4,O15504 5 +Sulfide oxidation to sulfate 0.7419805001964307 0.9725933437014376 0.3307554521638476 1.0 0.7278668602174612 3 Q9UBX3 1 +Golgi to er retrograde transport 0.328466327418563 0.965364074592729 0.3343624888927761 1.0 0.7293374635474078 71 P49755,Q9UJW0,Q9H0B6,O43731,P24390,O75935,P62820,Q9BVK6,Q15363,Q13561,Q12981,Q9P2W9,Q9Y3B3,Q07866,O15260,Q10472,Q9H0U4 17 +Activation of gene expression by srebf srebp 0.426590927306879 0.9596850901406035 0.3372137294585324 1.0 0.7315383112711665 16 O75845,O00767,Q14534,Q9HCL2,P04035,P37268 6 +Class b 2 secretin family receptors 0.7377667021113713 0.955883034517389 0.3391313312080695 1.0 0.7315383112711665 3 P63218 1 +Heme biosynthesis 0.585493710855234 0.9511727154131944 0.3415167066151772 1.0 0.7315383112711665 6 Q7KZN9,P22830 2 +Biological oxidations 0.3419595343646636 0.9506706838565654 0.3417715745699086 1.0 0.7315383112711665 43 O43169,Q99735,Q8TB61,Q16850,P21964,Q9NX62,P07099 7 +Miro gtpase cycle 0.6480901690669886 0.950185572801131 0.3420179680271369 1.0 0.7315383112711665 4 Q8IWA4,Q8IXI1,Q8IXI2 3 +Antigen presentation folding assembly and peptide loading of class i mhc 0.412782846351604 0.9498508385660702 0.3421880496132319 1.0 0.7315383112711665 18 Q6P179,P51572,P27824,Q03519,Q9Y6B6,Q9NZ08,P55735,P10321,P04439 9 +Pre notch expression and processing 0.4718825898972245 0.9463328440183556 0.3439788463442199 1.0 0.732038314439147 12 Q11206,Q15363,Q9UBV2,P16615 4 +Regulation of cholesterol biosynthesis by srebp srebf 0.3920622600826016 0.94195920828457 0.3462135247783342 1.0 0.7334983350423366 25 Q12770,Q9UBM7,O75845,O00767,Q14534,Q9HCL2,Q16850,P04035,P37268 9 +Calnexin calreticulin cycle 0.4909573779915827 0.9410672300763592 0.3466704075197655 1.0 0.7334983350423366 10 Q9UKV5,Q9GZP9,Q9UBV2,O60858 4 +Reactions specific to the complex n glycan synthesis pathway 0.7323943661971724 0.9346303782138616 0.3499788179089624 1.0 0.7369086422336525 3 Q16706,Q10469 2 +Diseases associated with glycosaminoglycan metabolism 0.5804178270849315 0.9275031745073136 0.3536653443288107 1.0 0.7381062570472834 6 Q8NCH0,P15291 2 +Rhoc gtpase cycle 0.3699455748000276 0.923558306598577 0.3557163299102486 1.0 0.7381780348899232 30 P41440,P27105,P49257,Q8TAA9,P42167,Q5T8D3,Q13190,Q14739 8 +G1 s specific transcription 0.4966486948123342 0.9233773122063804 0.3558106107795171 1.0 0.7381780348899232 9 P04818,P00374,P28749,P31350,P04183 5 +Metabolism of steroid hormones 0.6401513961285452 0.9166646271551082 0.3593184073909419 1.0 0.7381780348899232 4 Q53GQ0 1 +Cell surface interactions at the vascular wall 0.4554697569595855 0.9137459027018584 0.3608503780835699 1.0 0.7381780348899232 13 P14174,P35613,Q08722,P54709,P05556,Q92896 6 +Integrin cell surface interactions 0.637297057866903 0.9046419008251624 0.3656551297398978 1.0 0.7381780348899232 4 Q08722 1 +Aflatoxin activation and detoxification 0.6088306871208098 0.8997712171655563 0.3682420147032594 1.0 0.7381780348899232 5 Q99735,O14880 2 +Platelet activation signaling and aggregation 0.3287561704422067 0.8922448593518182 0.3722617024086718 1.0 0.7381780348899232 53 Q8NBM8,P63218,O43852,Q6UXV4,P13473,Q96JJ7,Q9UHQ9,P07602,Q8NBX0,Q8NCG7,Q9NZJ7,Q9Y6I9,Q8N2K0,Q92520,O94919 15 +G beta gamma signalling through pi3kgamma 0.6292634899252277 0.8708975715825749 0.3838100828685098 1.0 0.749884517507272 4 P31751,P63218 2 +Intraflagellar transport 0.4777916472544037 0.8665697340465214 0.3861778026609113 1.0 0.752938844294179 10 Q7Z4L5,Q92973,Q13885,A0AVF1,Q9BUF5 5 +N glycan trimming in the er and calnexin calreticulin cycle 0.4003349359513867 0.8627845192914315 0.388255952201435 1.0 0.7548820463415089 17 Q9UKV5,Q9GZP9,Q9UBV2,O60858 4 +Interactions of vpr with host cellular proteins 0.3464233189069841 0.8575511407526135 0.3911403641953677 1.0 0.7559336356332731 34 Q12769,Q8NFH5,P12236,P12235,Q9BTX1,Q7Z3B4,O15504 7 +Nuclear envelope breakdown 0.3322399830614126 0.8460909898026117 0.3975019867611562 1.0 0.7601544842720194 43 P50402,Q8NFH5,P42167,Q86Y07,Q9BTX1,Q7Z3B4,O15504 7 +Protein protein interactions at synapses 0.4422645920398939 0.8315221531204708 0.4056787188241662 1.0 0.7679196627153626 13 O95197 1 +Cytoprotection by hmox1 0.3196843788973637 0.8241808061478162 0.4098368313086751 1.0 0.7710676772330328 67 P00403,P09601,P30519,P28072,P13073,P49721,O43819,Q9Y6N1,P28074,Q8N8Q8,P43686,O00487,P20674,O75880 14 +Beta oxidation of butanoyl coa to acetyl coa 0.6135303314818219 0.8052769533559992 0.4206598780721926 1.0 0.7840287427531096 4 P40939 1 +Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.6119462043646995 0.7987086744537802 0.4244593557505736 1.0 0.7869028839269063 4 Q7Z434 1 +Activation of kainate receptors upon glutamate binding 0.6970945294309577 0.7967754925531114 0.4255814307770875 1.0 0.7869028839269063 3 P63218 1 +Metabolism of folate and pterines 0.4729525394996333 0.7933040049460436 0.4276007240168122 1.0 0.787268551972156 9 Q9H2D1 1 +Phase i functionalization of compounds 0.4252627765489549 0.7925348830558868 0.428048860339377 1.0 0.787268551972156 14 O43169,P07099,Q16850 3 +Adp signalling through p2y purinoceptor 1 0.6942097026603744 0.7856742696138342 0.4320583411206748 1.0 0.787268551972156 3 Q9UBI6,P63218 2 +Signaling by gpcr 0.325932435825698 0.7643428655142342 0.4446629470040431 1.0 0.796509919730426 42 Q14155,P42892,P31751,P07602,Q8NCG7,Q9NZJ7,P63218,Q8N2K0 8 +Synthesis of dolichyl phosphate 0.6837464193173972 0.745661427146139 0.4558719658087478 1.0 0.80775750665598 3 Q86YN1 1 +Hemostasis 0.2846741423623014 0.7440471607186239 0.4568479442989466 1.0 0.8083139800270335 125 P14174,Q8NBM8,Q9UHQ9,Q8NCG7,Q08722,Q8N2K0,Q6UXV4,P13473,Q8NBX0,Q9Y6I9,Q92520,P20020,O94919,P23634,O43852,Q16537,P35613,Q9NZJ7,P63218,Q07866,P16615,Q9H0B6,Q08380,Q96JJ7,P42785,P07602,Q8IWA4,Q00535,Q92896 29 +Autophagy 0.3150436910362221 0.738535996921301 0.4601888010660115 1.0 0.8111408665254447 49 Q7Z3C6,O96008,Q9NS69,Q8N4H5,P21796,P08670 6 +Peroxisomal protein import 0.3748366680455819 0.7321178596735836 0.4640966338321755 1.0 0.8169973528748007 22 Q15067,P39210,O15254,O15228 4 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.4674001236832512 0.7223038475863076 0.4701076878649552 1.0 0.820337915324347 8 Q5KU26,P10321,P05556,P04439,P15151 5 +Activation of ampk downstream of nmdars 0.5912913348262101 0.7138479744784358 0.4753211905986509 1.0 0.8232610199450581 4 Q9BUF5,Q13885 2 +Synthesis of pips at the golgi membrane 0.4952443939874887 0.6927733280275231 0.4884518129611892 1.0 0.8326911642047657 7 Q9NTJ5,Q10713 2 +Akt phosphorylates targets in the cytosol 0.5840429912695788 0.6844600079172789 0.4936847345145079 1.0 0.8374203748652319 4 P31751 1 +Sars cov 1 infection 0.3956583655979983 0.6696327875659575 0.503091907465266 1.0 0.8412895152538675 15 Q11206,P27824,Q10472 3 +Constitutive signaling by akt1 e17k in cancer 0.5553562377494036 0.6682081531643926 0.5040007317799038 1.0 0.8412895152538675 5 P31751,P49841 2 +Depolymerisation of the nuclear lamina 0.4420578358330732 0.666127379944809 0.5053296851567128 1.0 0.8412895152538675 10 P42167 1 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.4493496692547171 0.6651204981032576 0.5059734249253502 1.0 0.8412895152538675 9 P04035,Q9NR77 2 +Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.6063829787234059 0.6545621163305243 0.5127497218383585 1.0 0.8460976497474568 2 P04637 1 +Activation of rac1 downstream of nmdars 0.6581838144046265 0.6498147405891306 0.5158118961545801 1.0 0.8484471239489602 3 Q14155 1 +Degradation of cysteine and homocysteine 0.5481413079934883 0.6377754764837784 0.5236198454680023 1.0 0.8562166645708887 5 Q9UBX3 1 +Tp53 regulates transcription of cell death genes 0.4822356525134792 0.6297670809399821 0.5288469864223919 1.0 0.8584539454019292 7 Q658P3 1 +Ros and rns production in phagocytes 0.4490227174443179 0.6260225516892793 0.5313001495187741 1.0 0.8601488476386533 8 Q93050 1 +Transferrin endocytosis and recycling 0.4256788585851891 0.6171117703152476 0.5371610056081186 1.0 0.8601488476386533 11 Q658P3,Q93050,Q9Y487 3 +Cellular response to chemical stress 0.2952619645107928 0.5839923783980703 0.5592254398014203 1.0 0.8773092165749045 77 Q96HE7,P00403,P09601,P30519,P28072,P13073,P49721,O43819,Q9Y6N1,Q8N8Q8,P28074,Q8TED1,P43686,O00487,P20674,O75880 16 +Hs gag degradation 0.6385347119114314 0.5783554787420471 0.563024145529925 1.0 0.8801586866290876 3 P08236 1 +Sumoylation of sumoylation proteins 0.3417623759152267 0.5759537554809065 0.5646464396422561 1.0 0.8804050583021084 27 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4 +Regulation of glucokinase by glucokinase regulatory protein 0.3417623759152267 0.5759537554809065 0.5646464396422561 1.0 0.8804050583021084 27 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4 +Retrograde transport at the trans golgi network 0.3781934865261103 0.5548818389382937 0.5789754847363444 1.0 0.880951532098954 15 O60499 1 +Neutrophil degranulation 0.2630849705080907 0.5490647374049251 0.5829610236192366 1.0 0.880951532098954 171 Q969Q5,P14174,O95298,P27105,Q5T9A4,Q07065,Q8NF37,Q99536,Q9H7Z7,Q08722,Q4KMQ2,Q9BTY2,Q9NQX7,Q96CS3,P13473,P30519,P17900,P11279,P15586,Q8WVQ1,O43681,Q9NZJ7,O00487,P04439,Q93050,P61026,O14975,Q9H0U3,P10619,P15291,Q13636,P42785,P07602,P08236,Q13510,O00264,P53634,O15260,P09960 39 +Export of viral ribonucleoproteins from nucleus 0.3319967203586939 0.5483642528602831 0.5834418167695543 1.0 0.880951532098954 29 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4 +Sars cov infections 0.2982082981105378 0.5434041353562556 0.5868515790684925 1.0 0.880951532098954 64 P23458,P49356,Q99720,Q9H0U3,Q16706,P27824,Q10469,P46977,P05023,P21964,Q11206,P04843,Q10472,P49354,P49841 15 +Tp53 regulates transcription of caspase activators and caspases 0.5750938673341568 0.5317561569423807 0.5948948920397181 1.0 0.880951532098954 2 P04637 1 +Sumoylation of ubiquitinylation proteins 0.3330782548181334 0.5289249121557243 0.5968575395550451 1.0 0.880951532098954 28 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4 +Synthesis of ip3 and ip4 in the cytosol 0.5741551939924808 0.5281983977078626 0.5973616413842451 1.0 0.880951532098954 2 Q01968 1 +Negative regulation of nmda receptor mediated neuronal transmission 0.4922684501537491 0.5280101312392393 0.597492304181102 1.0 0.880951532098954 6 P07196 1 +Postmitotic nuclear pore complex npc reformation 0.3457862716328336 0.5250108878513797 0.5995756220891768 1.0 0.8820741856458219 23 Q7Z3B4,Q9BTX1,Q8NFH5 3 +Phase ii conjugation of compounds 0.3354546874923755 0.5229856226845687 0.6009842583932741 1.0 0.8820741856458219 27 Q9NX62,Q99735,P21964 3 +Prevention of phagosomal lysosomal fusion 0.5397620538509749 0.5108513856418853 0.6094551243914998 1.0 0.8869195997708383 4 P20339,O14964,P51149 3 +G alpha q signalling events 0.3974853233188112 0.5047591187752086 0.6137280325061818 1.0 0.8869195997708383 12 Q8N2K0,Q8NCG7,P63218 3 +Inla mediated entry of listeria monocytogenes into host cells 0.56602002503128 0.4977096764205356 0.6186886868260171 1.0 0.8869304788970778 2 P35222 1 +Disorders of transmembrane transporters 0.2896194080634393 0.4916689927293418 0.6229533616264011 1.0 0.887390706969853 75 Q12769,Q8NFH5,O14678,Q9GZP9,Q9UBV2,P49721,P35613,P28074,Q9BTX1,O00487,Q7Z3B4,O15504 12 +Insulin receptor recycling 0.4160497592996532 0.4888506001878923 0.624947471482967 1.0 0.8874222982360411 9 Q93050,Q9Y487 2 +Galactose catabolism 0.5566332916145066 0.4633381025644941 0.6431220383833101 1.0 0.8995975607045098 2 Q96G03 1 +Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.600101539564154 0.4457258515771379 0.6557952883797715 1.0 0.910559482548082 3 P28749 1 +G protein beta gamma signalling 0.4426800655189145 0.4442953228581477 0.6568290823251566 1.0 0.910559482548082 7 P31751,P63218 2 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.5500625782227666 0.4398253265439067 0.6600636228852081 1.0 0.912325561928466 2 Q16539 1 +Sumoylation of transcription factors 0.597783817861111 0.4380819339734604 0.6613268900695937 1.0 0.9131674960802696 3 O75928 1 +Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.4965389867784422 0.4292259224388474 0.6677588199309141 1.0 0.9178972626186734 5 Q92600 1 +Pi metabolism 0.3489821675678936 0.4271027083976363 0.6693045203468384 1.0 0.9178972626186734 16 P48739,Q9NTJ5,Q10713,Q8NCE2,Q9BTU6 5 +Methylation 0.4370768642359626 0.4190032023832304 0.6752137919496146 1.0 0.924116130942806 7 P21964,P78417 2 +Transport of the slbp dependant mature mrna 0.3129495087583251 0.4116176433137786 0.6806196976783341 1.0 0.9249540820894244 30 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4 +P75ntr negatively regulates cell cycle via sc1 0.5397371714643182 0.4038465260483777 0.6863255808002564 1.0 0.9249540820894244 2 Q13547 1 +Ovarian tumor domain proteases 0.402674611678512 0.3925093782816093 0.694681883322017 1.0 0.9249540820894244 8 Q13546,P06493,Q7Z434 3 +Ub specific processing proteases 0.2826101223951178 0.3865089683758985 0.6991197618853844 1.0 0.92645068055159 73 Q92530,O14964,Q70CQ2,Q12834,Q969V5,P28072,P49721,P51784,Q9Y277,P45880,P28074,P21796,Q15388,Q9NZL9,O00487,P43686,Q9UPU5,Q13546 18 +Free fatty acids regulate insulin secretion 0.5341051314142555 0.3847474148245602 0.7004245623201553 1.0 0.9268177146909352 2 O95573 1 +Plasma lipoprotein assembly remodeling and clearance 0.3304471480178017 0.3582848200047083 0.7201301769920672 1.0 0.9430597815018064 18 Q9BU23,O15118,Q6PIU2,Q8WTV0 4 +Recycling of eif2 gdp 0.4510274858176192 0.3564691009780246 0.7214892881541659 1.0 0.9430702680367188 6 P49770,Q13144 2 +Nuclear import of rev protein 0.3026738884716593 0.3511695846702495 0.7254611267651405 1.0 0.9464894700599404 31 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4 +Beta oxidation of hexanoyl coa to butanoyl coa 0.4729066987591177 0.3408918170138734 0.733185025333315 1.0 0.9516849224766092 5 P40939 1 +Assembly and cell surface presentation of nmda receptors 0.3843773441965582 0.3297091345590174 0.7416197509844731 1.0 0.9571730867631608 9 Q9BUF5,Q13885,P07196 3 +Sulfur amino acid metabolism 0.3728583871671604 0.3280173255874278 0.7428985628065248 1.0 0.9571730867631608 11 Q9Y6N5,Q9UBX3,Q13126 3 +Constitutive signaling by ligand responsive egfr cancer variants 0.4678985280300738 0.3229094336822506 0.7467638316795748 1.0 0.9572840303256992 5 P07900,P19174,P22681,Q16543 4 +Constitutive signaling by egfrviii 0.4678985280300738 0.3229094336822506 0.7467638316795748 1.0 0.9572840303256992 5 P07900,P19174,P22681,Q16543 4 +Signaling by egfr in cancer 0.4678985280300738 0.3229094336822506 0.7467638316795748 1.0 0.9572840303256992 5 P07900,P19174,P22681,Q16543 4 +Signaling by hippo 0.4420426065163018 0.3212720636984839 0.748004225105404 1.0 0.9579944020616 6 Q4VCS5,P31946,Q9UDY2,Q07157,Q13043 5 +Beta oxidation of lauroyl coa to decanoyl coa coa 0.4831553847235924 0.3104633147996857 0.7562086526746621 1.0 0.9640797069715328 4 P40939 1 +Glutamate neurotransmitter release cycle 0.5514372167401967 0.2955784603108041 0.7675520251784627 1.0 0.9732085623516202 3 Q96QD8 1 +Rhoh gtpase cycle 0.3140688607138792 0.2731608009812249 0.7847296107401274 1.0 0.9847154832909376 22 Q9BXS4,P27105,Q9Y6M7,O75323,Q8TAA9 5 +Ca2 pathway 0.4030538626912879 0.2726586966694138 0.7851155873080233 1.0 0.9847154832909376 7 Q08209,P63218 2 +Interleukin 35 signalling 0.4706205669968122 0.2705478424998769 0.7867388156868371 1.0 0.9847154832909376 4 P23458 1 +Interleukin 27 signaling 0.4706205669968122 0.2705478424998769 0.7867388156868371 1.0 0.9847154832909376 4 P23458 1 +Plasma lipoprotein clearance 0.34738548274194 0.2667537020840681 0.7896588032377938 1.0 0.9847154832909376 13 O15118,Q6PIU2,Q8WTV0 3 +Sealing of the nuclear envelope ne by escrt iii 0.3755485893417042 0.2657947602108739 0.7903972788587246 1.0 0.9847154832909376 8 Q13885,Q8WUX9,O43633,P04350,Q8NC56,Q9BUF5,P53990 7 +Signaling by erbb2 in cancer 0.4677520350657531 0.2616806737874743 0.7935676415583972 1.0 0.9847154832909376 4 P07900,P19174,Q16543 3 +Signaling by erbb2 ecd mutants 0.4677520350657531 0.2616806737874743 0.7935676415583972 1.0 0.9847154832909376 4 P07900,P19174,Q16543 3 +Fceri mediated ca 2 mobilization 0.4677520350657403 0.2616806737874351 0.7935676415584274 1.0 0.9847154832909376 4 Q08209,P19174,O43865 3 +Nuclear pore complex npc disassembly 0.2902591130041755 0.2434506008123365 0.807656348841084 1.0 0.996014366592008 31 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4 +Rhoj gtpase cycle 0.3006587242688078 0.2404408896666116 0.8099884823775358 1.0 0.9971054693627108 27 Q14155,Q658P3,Q9Y6M7,O75323,Q8TAA9,P42167,P17302 7 +Abc family proteins mediated transport 0.2720893350948901 0.238238049615026 0.8116964672291553 1.0 0.9971054693627108 54 P40855,P08183,Q9GZP9,Q9UBV2,P49721,O75027,P56589,P28074,O00487,P43686 10 +Arms mediated activation 0.4856070087609428 0.2377135578938406 0.8121032673814166 1.0 0.9971054693627108 2 Q9ULH0 1 +Displacement of dna glycosylase by apex1 0.4759073842302733 0.2124495146653034 0.8317563601724447 1.0 1.0 2 P29372 1 +Ephrin signaling 0.4350140933291734 0.2123631564821536 0.8318237270851987 1.0 1.0 5 Q14155,Q13153,Q16512,Q13177 4 +Dap12 interactions 0.4350140933291625 0.2123631564821194 0.8318237270852253 1.0 1.0 5 P01889,P19174,P10321,P62993 4 +Rhof gtpase cycle 0.3083372675748863 0.2115982637236166 0.8324204640088828 1.0 1.0 18 Q8TAA9,P42167,Q9Y6M7 3 +Activation of smo 0.469023779724641 0.1954247517326877 0.8450604410763025 1.0 1.0 2 Q9Y496 1 +Rho gtpase cycle 0.2500677152083597 0.1952687161539637 0.8451825865232991 1.0 1.0 157 P50402,Q9BXS4,Q15904,Q07065,Q9Y512,Q8TAA9,O95202,P08670,Q14739,P41440,Q96CS3,P51572,P30519,O43396,P51648,Q5T8D3,Q86Y07,Q14155,Q658P3,Q86XL3,Q96DH6,Q13505,O15173,Q9Y6M7,A4D1P6,P42167,P49257,O15498 28 +Signaling by ntrk3 trkc 0.4674593241551791 0.1916617843683442 0.8480071426080518 1.0 1.0 2 P19174 1 +Signaling by fgfr4 in disease 0.4674593241551791 0.1916617843683442 0.8480071426080518 1.0 1.0 2 P19174 1 +Nef mediated downregulation of mhc class i complex cell surface expression 0.4427050720100266 0.188823125500134 0.8502314463441769 1.0 1.0 4 Q10567,Q9BXS5,P04439 3 +G alpha 12 13 signalling events 0.3815917732589603 0.1882648574977115 0.8506690323864983 1.0 1.0 7 P63218 1 +Neuronal system 0.2652028880149185 0.1782537197579408 0.8585237229346325 1.0 1.0 50 P41440,Q14155,O95197,P51812,Q96RD7,P21964,P63218,Q96QD8 8 +Dscam interactions 0.4348778960551023 0.1678378235566311 0.8667108656552569 1.0 1.0 4 Q16512,Q13153,Q16539 3 +Rnd3 gtpase cycle 0.3067413690340088 0.1627746199923612 0.87069589204039 1.0 1.0 16 O43396,Q07065 2 +Cobalamin cbl vitamin b12 transport and metabolism 0.4152754140116542 0.1531394201505215 0.8782883297101742 1.0 1.0 5 O14678 1 +Diseases of carbohydrate metabolism 0.3429759272169772 0.1422840318254494 0.8868556589554917 1.0 1.0 9 P08236,P15586,P10253 3 +Cytosolic iron sulfur cluster assembly 0.367596364775937 0.1372853078750214 0.8908052830938902 1.0 1.0 7 Q96T76,O75027,P18074,Q9Y5Y2,P28340,P53384 6 +Cdc42 gtpase cycle 0.2700887932135622 0.1352664202750582 0.8924012337666429 1.0 1.0 34 Q14155,Q658P3,Q8TAA9,A4D1P6,P42167,Q14739 6 +Nade modulates death signalling 0.4414893617021116 0.135056064929856 0.8925675469380083 1.0 1.0 2 P42575 1 +Ns1 mediated effects on host pathways 0.2722736696456702 0.1321564407428186 0.8948605540965977 1.0 1.0 33 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4 +Interactions of rev with host cellular proteins 0.2695246761534527 0.13039067540475 0.8962573435588352 1.0 1.0 34 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4 +Rac1 gtpase cycle 0.2644198732321585 0.1299846251083264 0.8965785908690198 1.0 1.0 42 Q14155,P50402,Q8TAA9,P42167,Q86Y07,Q14739 6 +Synthesis of pips at the early endosome membrane 0.4820031298904632 0.1274549595103139 0.898580319478449 1.0 1.0 3 Q9BTU6,O00443 2 +The phototransduction cascade 0.4181012936939436 0.1259171652384994 0.8997974949288059 1.0 1.0 4 P49356 1 +Regulation of lipid metabolism by pparalpha 0.2932956353562858 0.1205553905315314 0.9040432042433332 1.0 1.0 20 Q86X55,P50416,Q15067,P23786,P04035,P37268,P33121 7 +Diseases of immune system 0.4333541927409158 0.1196188271291938 0.9047851049201336 1.0 1.0 2 P09429 1 +Irak1 recruits ikk complex 0.4333541927409111 0.1196188271291854 0.9047851049201404 1.0 1.0 2 P61088 1 +Viral messenger rna synthesis 0.264865287838658 0.1131393564718707 0.9099200733409732 1.0 1.0 35 Q7Z3B4,O15504,Q9BTX1,Q8NFH5 4 +Glycogen storage diseases 0.4745193616234338 0.1130784261533091 0.9099683787107083 1.0 1.0 3 P10253 1 +Rhobtb1 gtpase cycle 0.2974758844515326 0.109918519923447 0.9124739947666208 1.0 1.0 16 O43396 1 +Apc c cdc20 mediated degradation of cyclin b 0.330687018352677 0.1064743595994337 0.9152059978252448 1.0 1.0 10 Q96DE5,Q9UJX5,Q12834,P06493,Q9UJX2,P30260 6 +Zbp1 dai mediated induction of type i ifns 0.4088916718847787 0.104740495212189 0.9165817281376094 1.0 1.0 4 Q08211,O15111,Q13546 3 +Rip mediated nfkb activation via zbp1 0.4088916718847787 0.104740495212189 0.9165817281376094 1.0 1.0 4 Q08211,O15111,Q13546 3 +Traf6 mediated nf kb activation 0.3964923269652531 0.1024186584318523 0.9184243742606432 1.0 1.0 5 Q14258,P09429,O15111,Q7Z434 4 +Collagen biosynthesis and modifying enzymes 0.3255671233930944 0.1010616719558029 0.9195015035702044 1.0 1.0 11 O15460,Q32P28 2 +Constitutive signaling by overexpressed erbb2 0.4676056338028266 0.1004747984899507 0.9199673894683588 1.0 1.0 3 P07900,Q16543 2 +Antigen activates b cell receptor bcr leading to generation of second messengers 0.4676056338028266 0.1004747984899507 0.9199673894683588 1.0 1.0 3 Q13586,O43865 2 +Ikk complex recruitment mediated by rip1 0.4023168440826471 0.0904387305317687 0.9279385802673416 1.0 1.0 4 P61088,O15111,Q13546 3 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.4013171289117513 0.0883242541372735 0.9296189622718432 1.0 1.0 4 P11802 1 +Interferon alpha beta signaling 0.3262233375156923 0.0881342575724278 0.9297699687046544 1.0 1.0 10 P55265,P10321,Q9Y3Z3,P61221,P18031,P01889,P04439,P42224,P23458 9 +Acyl chain remodeling of cl 0.4601825279763973 0.0876682114391304 0.9301403859100624 1.0 1.0 3 P40939 1 +Pyruvate metabolism 0.3043677592448212 0.0775972603562965 0.9381484217307748 1.0 1.0 14 Q15118,P21796,P35613 3 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.2981817919309762 0.0774648043107309 0.9382537892029092 1.0 1.0 15 Q02818,Q9BTY2,Q07065 3 +Notch4 activation and transmission of signal to the nucleus 0.3911138923654447 0.0566671232937283 0.954810363725739 1.0 1.0 2 Q92542 1 +Met activates rap1 and rac1 0.3838447088290477 0.0539529414010718 0.9569726569162644 1.0 1.0 4 P63000,Q96N67,P62993 3 +Pyroptosis 0.3751957406827488 0.052063890873903 0.9584777848332446 1.0 1.0 5 P09429,P04637,Q8WUX9,O43633 4 +Ticam1 rip1 mediated ikk complex recruitment 0.4334898278560354 0.0477661092205449 0.9619026466350028 1.0 1.0 3 P61088,Q13546 2 +Chl1 interactions 0.3826658322903554 0.0473496078362101 0.9622345910567488 1.0 1.0 2 P05556 1 +Glucuronidation 0.4319248826291166 0.0457199632205846 0.9635334520970869 1.0 1.0 3 Q9NUJ1,Q16851 2 +Signaling by insulin receptor 0.2975172239229271 0.0448816368134887 0.9642016537935733 1.0 1.0 14 P31751,Q93050,Q9Y487 3 +Trna modification in the nucleus and cytosol 0.3000881988566725 0.0327339845000312 0.9738867226930346 1.0 1.0 13 Q5VV42,O75648 2 +Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.3507108159280039 0.029615119565371 0.9763740069333636 1.0 1.0 6 Q15067,O95864 2 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.4162754303599464 0.026979415557678 0.9784761520602524 1.0 1.0 3 P07900,P00374 2 +Interaction between l1 and ankyrins 0.3663118346900412 0.0243811350542272 0.9805485958990928 1.0 1.0 4 O15020,Q01082,Q12955 3 +Generation of second messenger molecules 0.3614155966176181 0.0236935386596167 0.9810970599632218 1.0 1.0 5 P19174,Q16512,Q13153,Q13177 4 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3580357946700679 0.017246620247593 0.9862398701308552 1.0 1.0 5 P31751 1 +Met activates ras signaling 0.4000000000000098 0.010670597581809 0.9914862565000584 1.0 1.0 3 Q96P70,P62993 2 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e31418b39be59996d4ff369c75bd92a029a8898e --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Blood group systems biosynthesis", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective b4galt1 causes b4galt1 cdg cdg 2d", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective ext2 causes exostoses 2", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Elevation of cytosolic ca2 levels", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr3a mediated il10 synthesis", "Fertilization", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Il 6 type cytokine receptor ligand interactions", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interaction with cumulus cells and the zona pellucida", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 2 signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Na cl dependent neurotransmitter transporters", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of gene expression by hypoxia inducible factor", "Regulation of gene expression in beta cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "Runx3 regulates yap1 mediated transcription", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of o glycan biosynthesis", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Yap1 and wwtr1 taz stimulated gene expression", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG5", "ALKBH5", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APEH", "APEX1", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP5", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP8", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BCAP31", "BCAS2", "BCKDHB", "BCS1L", "BET1", "BIRC6", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BSG", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC22", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDS2", "CENPH", "CENPI", "CENPK", "CENPU", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN7", "CLINT1", "CLNS1A", "CLTC", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT2", "CNOT9", "COASY", "COG3", "COG8", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD7", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ9", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CWC27", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEGS1", "DEK", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHPS", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSG2", "DSP", "DST", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM3C", "FAM49B", "FAM98B", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO21", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLCN", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FNTA", "FNTB", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGCX", "GGH", "GHDC", "GINS3", "GINS4", "GJA1", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GUSB", "GYS1", "H1F0", "H2AFX", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HECTD1", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILK", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INCENP", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITGB1", "ITM2B", "ITM2C", "ITPA", "IVD", "IWS1", "JAK1", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMO7", "LNPEP", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC1", "LRRC41", "LRRC8A", "LRRC8C", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "MAGED2", "MAGT1", "MAIP1", "MALT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MARC1", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MED14", "MED16", "MED18", "MED21", "MED23", "MED24", "MED4", "METTL1", "METTL3", "MFN1", "MFN2", "MGAT2", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MPV17", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTFMT", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTOR", "MTR", "MTX1", "MTX2", "MUL1", "MUT", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO6", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NARS2", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEK9", "NELFA", "NELFCD", "NF1", "NFRKB", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NSD1", "NSD2", "NSDHL", "NSF", "NSL1", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OBSL1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTULIN", "OXA1L", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCM1", "PCMT1", "PCNA", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMPCA", "PMPCB", "PMVK", "PNO1", "PNP", "PNPLA6", "POFUT1", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMK", "PON2", "POP1", "POR", "PPA1", "PPAT", "PPCDC", "PPIB", "PPID", "PPIH", "PPIL1", "PPIL4", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPH", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PVR", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB29", "RAB2A", "RAB31", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP2B", "RARS", "RARS2", "RB1", "RBBP5", "RBBP7", "RBL1", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIPK1", "RNF2", "RNF25", "RNF40", "RNMT", "RNPS1", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP7A", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A4", "SLC30A5", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLIT2", "SLK", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "ST3GAL4", "STAG1", "STAG2", 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0.0001476913167928 4.874999040450038e-06 +Cholesterol metabolism with bloch and kandutschrussell pathways 11 23 2.413811622400888 0.0157866218901783 7.092233009708738 23.070388349514563 1.3045876527781233 0.2885598195159411 3.1892169450204397 2.132138915277104 1.1515799969949023 0.3088028425519339 7.672440891884366e-06 0.1635258499471353 0.0480988323617951 0.0002303056568621 8.056107863146863e-07 +Glycerophospholipid biosynthetic pathway 6 10 2.3889535641611994 0.0168964378075546 3.058252427184466 7.264563106796117 0.3097224827204536 0.3481868464538606 1.7226376406937374 1.7873358580072474 1.274716840477959 0.2785476931941232 0.0003617379573792 0.1178616319260966 0.0251008323038497 0.0239571113561098 0.0012335596495353 +Glycerolipids and glycerophospholipids 4 7 2.263677877996009 0.0235939340670465 1.902439024390244 5.282926829268293 0.2570184705733445 0.3919307408190254 1.3234264111744822 1.6756363827898255 1.2288051208295987 0.2955621473168567 0.0007687310007342 0.0919337377678228 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0.0145863017156454 0.0002941476334404 1.1798382677149156e-06 +Glycosylation and related congenital defects 8 13 2.1864169445877057 0.0287851150384192 3.0266990291262137 8.905339805825243 -0.2985692153255816 0.4534611995117258 1.825325021383419 1.8137207990645048 1.0274721770258426 0.2816233185866196 0.0018579158445701 1.0 1.0 0.1131762501747812 1.0291992375111868e-05 +Metabolism of spingolipids in er and golgi apparatus 5 6 2.1509369220492363 0.0314811787744422 2.1432038834951457 4.12378640776699 1.255170581651192 0.2109312980793922 1.3711229283492827 1.3022449745711573 1.2018683368625842 0.2544377197345568 7.965265001886016e-05 1.0 1.0 0.0379575415698398 1.5721855343212837e-05 +Oxidative phosphorylation 13 34 2.134672128305272 0.0327878011885642 10.094660194174756 30.308252427184467 0.4493106572238387 0.4094278581483465 4.631390429635194 3.3340884045985604 1.35936739882113 0.3321380007425058 3.271849015597704e-06 0.0019537982219709 0.0014691652083679 3.079730523933523e-05 4.915457973009443e-06 +Kennedy pathway from sphingolipids 3 6 2.099547657072033 0.0357686513667339 1.8349514563106797 4.538834951456311 1.005685357170638 0.2842758763214292 1.1414272055653287 1.0616650240280194 1.1079123437614409 0.2814205551839854 0.0015547812541629 1.0 0.1253337423142017 0.0002735626391213 0.0036404640413724 +Oxidation by cytochrome p450 4 6 1.97926701749852 0.0477859509909279 2.3179611650485437 5.422330097087379 1.262256455948566 0.1900711291682963 1.161003800051733 0.6764315332620536 1.214909583878196 0.2447393771863318 0.0011448524525614 0.0607401038440192 0.0065261066260236 0.0379575415698398 0.002702316606903 +Mitochondrial immune response to sarscov2 8 9 1.9780649093239604 0.0479213845839807 3.674757281553398 8.939320388349515 0.2609941241524592 0.4397421433921452 2.181351609438601 1.0787927108046689 1.131627442692276 0.3196830596507893 0.6232593308220052 1.0 1.0 0.4573561220916043 0.1172853038507327 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..05d45735867435a660a1621c26272c22e6926171 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 601, + "title": "Average number of proteins per term", + "value": 10.678868552412645 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b13bfad8b2267b844000ea6b2b51d4d4616d6fc4 --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..894a5b7e03a8e1c216c8ab905080886f78f51625 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,118 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Electron transport chain oxphos system in mitochondria 0.5607428582191422 3.362024204811568 0.0007737334094977 0.3719865969503707 0.0570572489256048 56 O95298,Q7KZN9,O96000,P12236,Q9Y6M9,O14949,O43676,P03886,P00403,P12235,P24539,O75964,P56385,P13073,P03915,P00846,P21912,P56134,P36542,Q9UDW1,O75880 21 +Ferroptosis 0.6493458626505012 2.7971565326937973 0.005155454928714 0.9552401109134724 0.1239371364862858 23 P09601,Q9Y277,P45880,Q15043,P04035,P37268,P16435,Q96QD8 8 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.7200834022037934 2.7176143318101653 0.006575443324972 0.9810299001203376 0.1274787560744584 15 P11802,P50402,O75844,O60725,P42167,P49354,P55209 7 +Nonalcoholic fatty liver disease 0.4948280396660401 2.6661346545924443 0.007672895344291 0.9902373612933446 0.1397397000581492 49 P31751,P00403,O95298,P21912,O96000,P13073,O75306,Q9Y6M9,Q9P0J0,O14949,O95169,O95139,O43676,Q9UDW1,Q9NX14,P20674,Q86Y39,P49841 18 +Mitochondrial complex iv assembly 0.7479089826181038 2.6295883493138916 0.0085488315266386 0.9942579271791324 0.1436265584275916 13 Q9Y2R0,P00403,Q7KZN9,P13073,Q9Y241,O43819,Q9Y6N1,Q8N8Q8 8 +Sphingolipid pathway 0.7473119676765755 2.4165026438458623 0.0156704124320183 0.9999245838616398 0.1790143350188145 11 P04062,Q16739,Q96G23,Q16880,Q13510,Q06136,O95470 7 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.5933568941937228 2.4138116224008876 0.0157866218901783 0.9999297497869476 0.1790143350188145 23 Q15800,Q9UBM7,O00767,O75845,P35610,P37268,Q14534,Q15392,Q16850,P04035,Q14739 11 +Glycerophospholipid biosynthetic pathway 0.758423433963531 2.3889535641611994 0.0168964378075546 0.9999643416609372 0.1880510948581548 10 Q9HCL2,O14735,Q86UL3,Q9Y6K0,O15228,O95674 6 +Glycerolipids and glycerophospholipids 0.8183874428544093 2.263677877996009 0.0235939340670465 0.99999941398092 0.2220937211839964 7 Q9UG56,Q9BVG9,Q9HCL2,O14735 4 +Sphingolipid metabolism overview 0.7336065520892666 2.2631985448849816 0.0236234528923044 0.9999994245326056 0.2220937211839964 10 Q16739,P27544,Q96G23,Q16880,Q13510,Q06136,O95470 7 +Sphingolipid metabolism integrated pathway 0.7336065520892666 2.2631985448849816 0.0236234528923044 0.9999994245326056 0.2220937211839964 10 Q16739,P27544,Q96G23,Q16880,Q13510,Q06136,O95470 7 +Mitochondrial complex i assembly model oxphos system 0.5072651650429675 2.239417857836236 0.0251287405000195 0.9999997723291298 0.2220937211839964 32 Q96CU9,Q9NPL8,Q9Y375,O95298,P51970,O96000,O75306,Q9BUB7,Q9Y6M9,Q9P0J0,P03915,O95139,O95169,O43676,Q9NX14,P03886,Q9BQ95 17 +Glycosylation and related congenital defects 0.6673190954884485 2.1864169445877057 0.0287851150384192 0.999999976203492 0.2337818126768918 13 Q9H3H5,Q9H0U3,Q9BT22,P15291,Q10469,Q9BV10,O75340,Q2TAA5 8 +Metabolism of spingolipids in er and golgi apparatus 0.8477443609022579 2.1509369220492363 0.0314811787744422 0.999999995523414 0.2489498479399971 6 Q16739,Q16880,Q06136,O95470,Q10472 5 +Oxidative phosphorylation 0.4818857312718317 2.134672128305272 0.0327878011885642 0.9999999980112464 0.255915175510742 34 P00846,O75964,O95298,P56385,O96000,Q15904,P56134,O75306,Q9Y6M9,P03915,P24539,P03886,Q86Y39 13 +Kennedy pathway from sphingolipids 0.835978805344353 2.0995476570720335 0.0357686513667339 0.999999999688879 0.2687119933925885 6 Q9UG56,O95470,Q9Y6K0 3 +Eicosanoid synthesis 0.9139549436795996 2.013165258216391 0.0440972468010079 0.999999999998307 0.307510834558859 2 P09960 1 +Oxidation by cytochrome p450 0.8086908749213678 1.97926701749852 0.0477859509909279 0.9999999999998342 0.307510834558859 6 O43169,Q6UW02,P16435,Q16850 4 +Mitochondrial immune response to sarscov2 0.6926936343681441 1.9780649093239604 0.0479213845839807 0.9999999999998478 0.307510834558859 9 Q9Y375,Q99623,Q7Z434,Q9Y6M9,Q9H845,Q9Y276,Q9BQ95,O94826 8 +Influence of laminopathies on wnt signaling 0.659627874422496 1.9523338081243065 0.0508985860721058 0.9999999999999768 0.3141210468456452 11 P49354,O75844,P50402,O60725 4 +Copper homeostasis 0.7500366918132793 1.9462879978246568 0.0516201544978418 0.9999999999999852 0.3141210468456452 7 Q658P3,Q9Y6N1,O75880,O43819 4 +Cholesterol biosynthesis with skeletal dysplasias 0.7970335968188019 1.9274244168766903 0.0539267591253647 0.9999999999999966 0.3159769002008597 6 Q14739,Q15392,O75845,Q16850 4 +Mitochondrial complex iii assembly 0.668934387289053 1.9264365544797757 0.0540498867754781 0.9999999999999968 0.3159769002008597 10 O14949,Q9Y276,Q6DKK2,Q9UDW1 4 +Zinc homeostasis 0.8939299123904989 1.9248053636735032 0.0542537127353097 0.9999999999999972 0.3159769002008597 2 Q8TAD4 1 +Metapathway biotransformation phase i and ii 0.5243935127691279 1.916722580198642 0.0552731850478607 0.9999999999999986 0.3159769002008597 23 Q6UW02,Q99735,Q8NCH0,Q16850,P21964,Q7LGA3 6 +Proteoglycan biosynthesis 0.7878287211803421 1.8862975178137324 0.0592548735871749 1.0 0.3162567825503407 6 Q8NCH0,Q8WVQ1,Q8TB61,Q9NX62 4 +Statin inhibition of cholesterol production 0.7877922089453596 1.8861340513949996 0.0592768927087066 1.0 0.3162567825503407 6 P04035,P37268,Q14534,Q8WTV0 4 +Familial partial lipodystrophy fpld 0.6831298728960482 1.8607880298366013 0.0627741165599493 1.0 0.3162567825503407 8 P31751,O75844,O60725 3 +Cholesterol biosynthesis pathway 0.601961270030266 1.8091658616262776 0.0704252395136921 1.0 0.3413352334494273 13 Q15800,Q9UBM7,O75845,Q14534,Q16850,P04035,P37268 7 +Pkcgamma calcium signaling pathway in ataxia 0.8188360450563188 1.5893846408938066 0.111973580028938 1.0 0.4259248202366569 2 Q15118 1 +Progeriaassociated lipodystrophy 0.6030382407228362 1.570128657968325 0.1163851826597579 1.0 0.4317746591266329 10 O75844 1 +Triacylglyceride synthesis 0.746763728198699 1.51220346833917 0.1304821089802643 1.0 0.4585950146031513 5 Q9HCL2 1 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.7623315930772734 1.4378455085841622 0.1504778936884592 1.0 0.4998921049732523 4 P09601 1 +Nuclear receptors in lipid metabolism and toxicity 0.7797246558197928 1.413075239256159 0.1576336027306992 1.0 0.5012581758791019 2 P08183 1 +Vitamin d metabolism 0.8491392801251822 1.4039474776766585 0.1603344902558747 1.0 0.5041885146430344 3 P04062,P38435 2 +Omega3 omega6 fatty acid synthesis 0.6813073756284522 1.3993450823690343 0.1617095267041062 1.0 0.5041885146430344 6 Q15067,O95864,O15254 3 +Nephrotic syndrome 0.5302609748675235 1.3776607625181958 0.1683080511545578 1.0 0.5118782148899519 13 Q7Z4L5,Q14108,O75844 3 +Regulation of apoptosis by parathyroid hormonerelated protein 0.712279111949625 1.359539658947616 0.1739756442324058 1.0 0.5231542901235035 5 Q9BXK5,Q07820 2 +Ccl18 signaling pathway 0.575975374130083 1.3591640645938383 0.1740946056983372 1.0 0.5231542901235035 9 Q86UE4,P08670,P00403 3 +Nucleotidebinding oligomerization domain nod pathway 0.6276088637572999 1.3516674430487494 0.1764817245401015 1.0 0.5250768141019855 7 Q9P0J0 1 +Acquired partial lipodystrophy barraquersimons syndrome 0.7081042042132109 1.3409887778099752 0.1799240961864836 1.0 0.5300704990591993 5 O60725 1 +Sphingolipid metabolism in senescence 0.4943185416118308 1.3280384021122311 0.1841654208565444 1.0 0.5347025021004018 15 P04062,Q16739,O15269,Q96G23,Q13510,Q06136 6 +Envelope proteins and their potential roles in edmd physiopathology 0.4626247803669142 1.3127160682547652 0.1892786411030851 1.0 0.5378969338631204 17 P42167,O94901,Q14739 3 +Irinotecan pathway 0.7515644555694836 1.2860722195754897 0.1984178583687916 1.0 0.5572389386899242 2 O15118 1 +Sarscov2 b117 variant antagonises innate immune activation 0.7506257822277804 1.2818438227007003 0.1998974379228117 1.0 0.5587830706586506 2 Q7Z434 1 +Alzheimers disease and mirna effects 0.3423382744982897 1.261449859990182 0.2071468140069132 1.0 0.5737107613739856 81 Q9NQC3,O95197,P12236,P49721,P45880,Q96IX5,P12235,Q9Y277,P28074,P21796,O00487,Q07866,P49841,P16615,P31751,Q9H0B6,P28072,P05141,P43686 19 +Estrogen receptor pathway 0.7970968833959317 1.193526887516139 0.2326630884193672 1.0 0.6058771053149739 3 Q9HCL2 1 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.7000626174076354 1.1715977108192543 0.2413586075839973 1.0 0.6058771053149739 4 Q15118,P42345,P49841 3 +Vitamin d receptor pathway 0.4831182669535761 1.1657915005147172 0.2436987544893596 1.0 0.6058771053149739 14 Q96KA5,Q5VV42,Q92604,P08183 4 +Alzheimers disease 0.3312797437879465 1.100647252609075 0.2710502115013873 1.0 0.6353518125599373 80 P31751,Q9H0B6,Q9NQC3,O95197,P12236,P28072,P05141,P49721,P12235,Q9Y277,P45880,P28074,P21796,O00487,P43686,Q07866,P49841,P16615 18 +7oxoc and 7betahc pathways 0.5355490110150416 1.0863783306974235 0.277311644514125 1.0 0.637105370810211 8 O15118,Q9UBM7 2 +Degradation pathway of sphingolipids including diseases 0.6092092995862879 1.062100644157602 0.2881899977132858 1.0 0.656068896309412 6 P17900 1 +Cardiac progenitor differentiation 0.6939924906132685 1.0285012839284786 0.3037140871912065 1.0 0.6785582394123238 2 P49841 1 +Autosomal recessive osteopetrosis pathways 0.6855444305381968 0.9911937713655442 0.3215909714139613 1.0 0.6952380353229883 2 P51798 1 +Il10 antiinflammatory signaling pathway 0.6125994973106881 0.9163758572219024 0.3594697936021829 1.0 0.7212672081615646 5 P09601 1 +Sterol regulatory elementbinding proteins srebp signaling 0.3467462176394913 0.9031361817234071 0.366453623219765 1.0 0.7235494020437298 35 Q12770,O00767,Q9NR31,Q14534,Q9HCL2,Q9UKV5,Q16850,P04035,P37268,Q8WTV0 10 +Galanin receptor pathway 0.6645807259073779 0.8994815828359675 0.3683962013733466 1.0 0.7235494020437298 2 P14672 1 +Endothelin pathways 0.4872335795465274 0.8715907359897704 0.3834316863389992 1.0 0.7401913902553702 9 P16615,P00403 2 +Ppar signaling pathway 0.4189357848769283 0.8246696446120236 0.4095591699425027 1.0 0.7669558366774191 15 O00767,O14975,O15254,Q15067,P23786,O95864,P50416 7 +Interleukin1 induced activation of nfkb 0.6411138923654484 0.7986949557679539 0.4244673123777227 1.0 0.7777587034725957 2 Q13501 1 +Omega9 fatty acid synthesis 0.5479095246777846 0.7770257757929061 0.4371435631164764 1.0 0.7791737179065081 6 O95864,O00767 2 +Aryl hydrocarbon receptor pathway wp2873 0.5800222207448388 0.7739045180219363 0.438987257619879 1.0 0.7791737179065081 5 Q15185,O00170 2 +Folatealcohol and cancer pathway hypotheses 0.6276595744680823 0.7420462379729459 0.4580593214102075 1.0 0.7934297319129299 2 P11766 1 +Gastric cancer network 2 0.412302269483878 0.7093744978715892 0.4780921090351337 1.0 0.8124745177749789 14 Q86UE4 1 +Adipogenesis 0.3887494174070508 0.6966338597073594 0.4860319601916614 1.0 0.8124745177749789 16 O75844,O00767 2 +Intracellular trafficking proteins involved in cmt neuropathy 0.4395808334196389 0.6965357570111037 0.4860933723786425 1.0 0.8124745177749789 11 Q8TB36,Q9NR77 2 +Tryptophan metabolism 0.4055849485196403 0.6665048262136581 0.5050884798915067 1.0 0.8201158624115588 14 P40939,Q16836,Q15392,P51648 4 +Praderwilli and angelman syndrome 0.4556320497819965 0.6604795048693326 0.5089461665279491 1.0 0.8201158624115588 8 P11802,Q96RT8,Q15154 3 +Spinal cord injury 0.3691020608127817 0.6415059968924869 0.5211939859247674 1.0 0.8269931350363269 19 P11802,P14174,Q9NQC3,Q08722,P08670 5 +Allograft rejection 0.4425189814684285 0.6284335767360529 0.52971994707808 1.0 0.8269931350363269 9 P10321,P04439,P08183,P08670 4 +Angiopoietinlike protein 8 regulatory pathway 0.3395132228115728 0.6143022176017434 0.5390156374083608 1.0 0.8327722315743569 29 P41440,Q15382,P13807,P31751,O00767,P51812,Q14254,Q15642,P14672,O14654,P42345,P18031,P49841 13 +Ciliopathies 0.3635642157744548 0.5978019166302927 0.5499721116590375 1.0 0.8406425421763645 17 Q7Z4L5,Q10713,Q13432,Q9NQH7 4 +Genes related to primary cilium development based on crispr 0.404275196184397 0.5974682879975443 0.5501947732930779 1.0 0.8406425421763645 13 Q96J42,Q10713 2 +Mitochondrial long chain fatty acid betaoxidation 0.393722798277376 0.591337862284947 0.5542940654812325 1.0 0.8412392256419716 14 P40939,P49748,P23786,P50416,Q16836,P33121 6 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.5844806007509283 0.5677645800601592 0.5701948336869038 1.0 0.847569876815554 2 P08195 1 +Sulfation biotransformation reaction 0.6241001564945291 0.5273288406426159 0.5979652496176864 1.0 0.8634309292556452 3 O43252,P00390 2 +1q211 copy number variation syndrome 0.422469476665312 0.5222616590059717 0.6014881605521141 1.0 0.8634309292556452 9 Q9NPH0 1 +Lung fibrosis 0.490655878124119 0.5210440839648478 0.6023360618471949 1.0 0.8634309292556452 6 P09601 1 +Sars coronavirus and innate immunity 0.6183782797496038 0.5074865721235288 0.611813455748689 1.0 0.8634309292556452 3 P23458 1 +Apoptosis 0.4100364566107495 0.4912872224455661 0.6232233158369294 1.0 0.871184084003876 10 Q07820,Q9NR28 2 +Fatty acid transporters 0.5344395742016338 0.4908233013672219 0.6235514279812651 1.0 0.871184084003876 4 O95573,Q6P1M0,P33121 3 +Sarscov2 innate immunity evasion and cellspecific immune response 0.3923171759488483 0.4751650596183424 0.6346693292168504 1.0 0.877084429507413 12 P35613,P23458,Q7Z434 3 +Nuclear receptors metapathway 0.2900154670970474 0.4436254764530812 0.6573133833444342 1.0 0.8842020633986396 47 Q99735,O00767,P08183,Q9H2J7,P09601,Q9HCL2,Q15067,Q15043 8 +Mammalian disorder of sexual development 0.5419274092615673 0.4113759599317789 0.6807968787772374 1.0 0.8953369501043361 2 P35222 1 +Ethanol effects on histone modifications 0.3931854965442909 0.4024335753368714 0.687364964403637 1.0 0.8980572687099693 10 P41440,O14929,P04818,P00374 4 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.4224878075053432 0.3546134406708811 0.7228792055498747 1.0 0.9127109296963756 7 Q15118,P42345,P49770,P49841 4 +Riboflavin and coq disorders 0.4626312929466639 0.3043019290652508 0.7608978756228071 1.0 0.9370893919043178 5 Q8NI60,O75208 2 +Il18 signaling pathway 0.2776419540104681 0.2979634711289171 0.7657310437750535 1.0 0.939192565936341 55 Q9NQX7,O96008,P09601,P35613,Q9Y6M7,Q9NZJ7,P40939,Q16836 8 +Nad metabolism 0.4743490918914952 0.2822248843098055 0.7777710786346748 1.0 0.9488013455855184 4 P43490 1 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.3495224209678711 0.2784286320205365 0.7806833429353282 1.0 0.9497787228828588 13 Q32P28,O15460,O75718 3 +Cytosolic dnasensing pathway 0.3534212178279925 0.2619683907854238 0.793345811862405 1.0 0.959357812735021 12 P55265,Q9NZI8,O14802,O15160,Q7Z434,P19388,Q14258,O15111,Q9BUI4,Q13546,P52434 11 +Novel intracellular components of rigilike receptor rlr pathway 0.3573893944148126 0.2493993339171834 0.8030519003315417 1.0 0.9600779005158352 11 Q13526,Q12933,Q92841,Q7Z434,Q14258,Q16539,O15111,O43318,O00571,Q13546 10 +Nad biosynthetic pathways 0.4461223619450696 0.2481492024737705 0.8040189677841307 1.0 0.9600779005158352 5 P43490 1 +Glycosaminoglycan degradation 0.4219459806077665 0.2460610394834726 0.8056349819625248 1.0 0.9600779005158352 6 P06865,P08236,P15586 3 +Oxysterols derived from cholesterol 0.3961262845143533 0.2446582837477218 0.8067210312154689 1.0 0.9600779005158352 7 Q9UBM7 1 +Neural crest differentiation 0.3680712396752582 0.2326691453162595 0.816018330181822 1.0 0.963839489411042 8 Q9NR77 1 +Srebf and mir33 in cholesterol and lipid homeostasis 0.3927975765721598 0.2314531664530784 0.8169627653839875 1.0 0.963839489411042 7 O00767 1 +Sarscov2 and covid19 pathway 0.5272634537118064 0.2302462836417502 0.817900398668272 1.0 0.963839489411042 3 Q8WTV0 1 +Glucocorticoid receptor pathway 0.4158427848679278 0.2242808648656736 0.822538764597186 1.0 0.965608375067988 6 Q15185,P27105,Q13616 3 +Cellular proteostasis 0.5179968701095551 0.2070534360049751 0.8359681267005423 1.0 0.975566687664128 3 Q9UHV9,Q99471 2 +Type i interferon induction and signaling during sarscov2 infection 0.4434043564010469 0.1907407911163895 0.8487286786682486 1.0 0.9837863090161422 4 P23458 1 +Wntbetacatenin signaling pathway in leukemia 0.4430181590482137 0.1896808533220906 0.8495592252568682 1.0 0.9837863090161422 4 P48729,P35222,P49841 3 +Apoptosis modulation by hsp70 0.435858464630166 0.1704181004080626 0.8646813382837033 1.0 0.9988677675035352 4 Q13546 1 +Nanomaterial induced apoptosis 0.4323594028263753 0.1612754160876252 0.8718764849050404 1.0 0.9999957393662772 4 Q9NR28 1 +Heme biosynthesis 0.4115232836178227 0.1425529682237259 0.88664324392671 1.0 1.0 5 P22830 1 +Hostpathogen interaction of human coronaviruses interferon induction 0.3429700858176051 0.1284997085279869 0.8977535288734242 1.0 1.0 8 P23458,Q7Z434 2 +Hippoyap signaling pathway 0.4807511737089295 0.1249969108534353 0.900525995941508 1.0 1.0 3 P27348,P28347 2 +Supression of hmgb1 mediated inflammation by thbd 0.4333541927409158 0.1196188271291938 0.9047851049201336 1.0 1.0 2 P09429 1 +Vitamin d in inflammatory diseases 0.414527238572316 0.1175417498176872 0.906430761752306 1.0 1.0 4 Q08209,Q16539,O15111 3 +Methionine metabolism leading to sulfur amino acids and related disorders 0.4142836166951273 0.1169780789064836 0.9068774247012434 1.0 1.0 4 P55263 1 +Ketogenesis and ketolysis 0.4067585556052834 0.1000254335393249 0.9203241336551689 1.0 1.0 4 P23786 1 +Camkk2 pathway 0.3127180308331454 0.0899725680946353 0.9283090138852396 1.0 1.0 13 Q14155,Q13586,Q9Y3D6,P09601,Q14012,O76024 6 +Hostpathogen interaction of human coronaviruses autophagy 0.4469483568075191 0.0666923327625224 0.946826638292566 1.0 1.0 3 Q99570,P42345 2 +Leukocyteintrinsic hippo pathway functions 0.3318708868693319 0.0242411978102877 0.9806602166747772 1.0 1.0 7 P28347,P27348,P63000,Q16539,P51153,Q13043 6 +Insulin signaling in adipocytes normal condition 0.3593504133986431 0.0197302909188862 0.984258526820568 1.0 1.0 5 P31751,P14672 2 +Insulin signaling in adipocytes diabetic condition 0.3593504133986431 0.0197302909188862 0.984258526820568 1.0 1.0 5 P31751,P14672 2 +Serotonin and anxiety 0.3319774718397902 0.0103746428899491 0.9917223811056552 1.0 1.0 2 Q08209 1 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3f167abaf3bd87bb175d771dbbc05243144ad435 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir5093p alteration of yap1ecm axis", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Scfa and skeletal muscle substrate metabolism", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Srf and mirs in smooth muscle differentiation and proliferation", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC1", "ABCD3", "ABCF1", "ABCF2", "ABHD16A", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ACY1", "ADA", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "AMFR", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA4", "ANXA6", "AP1G1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APEX1", "APMAP", "APRT", "ARCN1", "ARF4", "ARFGAP1", "ARFIP2", "ARG2", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL6", "ARL8B", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG9A", "ATIC", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP8", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AURKA", "B3GALT6", "B4GALT1", "BAG3", "BAG4", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BLVRA", "BPTF", "BRCA1", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "C1QBP", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPZB", "CARM1", "CASK", "CASP2", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CEP170", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHRAC1", "CHST14", "CHUK", "CIP2A", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLPTM1L", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA3", "COASY", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COQ8B", "COQ9", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCP1A", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDAH2", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEGS1", "DEK", "DERL1", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHFR", "DHODH", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOLK", "DPAGT1", "DPM1", "DPP9", "DPYSL2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC10", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPRS", "EPS15L1", "ERCC2", "ERCC3", "ESD", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAH", "FAM120A", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHOD1", "FIS1", "FKBP10", "FKBP15", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAPDH", "GART", "GBA", "GBE1", "GCC2", "GCDH", "GCLC", "GDAP1", "GDI1", "GFPT1", "GGCX", "GGH", "GIGYF2", "GIPC1", "GJA1", "GLA", "GLB1", "GLS", "GLUD1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF2I", "GTPBP4", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPD1", "HTRA2", "HTT", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IGF2BP1", "IGF2BP3", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ITGB1", "ITM2C", "ITPA", "IVD", "JAK1", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIDINS220", "KIF1B", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD3", "LGALS3BP", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM7", "LSS", "LTA4H", "MACF1", "MAGT1", "MALT1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MED14", "MEPCE", "METTL3", "MFN2", "MGAT2", "MGST1", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTDH", "MTFMT", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTOR", "MTR", "MUT", "MYBBP1A", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NARS2", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCOR1", "NCSTN", "ND1", "ND5", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NF1", "NFATC2IP", "NFRKB", "NIPBL", "NKRF", "NME1", "NME2", "NONO", "NOP2", "NPC1", "NSD1", "NSDHL", "NSF", "NT5C3A", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAK1", "PAK2", "PAK4", "PANX1", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCM1", "PCNA", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDLIM7", "PDS5A", "PDS5B", "PEBP1", "PECR", "PELO", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PIBF1", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2A", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNP", "PNPT1", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PURA", "PUS1", "PVR", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB13", "RAB14", "RAB21", "RAB2A", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABAC1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RARS", "RB1", "RBBP7", "RBL1", "RBM14", "RBM17", "RBM39", "RBM4", "RBM47", "RBM5", "RBMX", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOA", "RHOG", "RIF1", "RIPK1", "RNASEH2A", "RNF2", "RNF40", "RNMT", "RNPS1", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP38", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RTCB", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SC5D", "SCAP", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDHA", "SDHB", "SEC13", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEL1L", "SEPT11", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SKP2", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A4", "SLC30A5", "SLC35B2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLIT2", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD3", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSNA1", "SSR4", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STEAP3", "STIM1", "STIM2", "STIP1", "STK4", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TAF5", "TALDO1", "TARDBP", "TBC1D4", "TBCA", "TBL2", "TCP1", "TEAD1", "TECR", "TELO2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TMED10", "TMEM38B", "TMEM43", "TMEM70", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIO", "TRIP10", "TRIP13", "TRMT2A", "TRRAP", "TSG101", "TSPYL1", "TTC19", "TTC21B", "TTC26", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUBGCP5", "TUFM", "TWISTNB", "TXNDC15", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2G2", "UBE2L3", "UBE2N", "UBE3A", "UBR5", "UBTF", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UPF1", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP10", "USP5", "USP7", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS16", "VPS18", "VPS33A", "VPS37B", "WAPL", "WARS", "WASF2", "WDHD1", "WDR1", "WDR5", "WDR74", "WFS1", "WIPI2", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF281", "ZNF318", "ZYG11B", "ZYX"], "leading_proteins": ["ABCB1", "ACAD9", "ACADVL", "ACOX1", "ACOX3", 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file mode 100644 index 0000000000000000000000000000000000000000..cbabfc03090cc07ba5beb690067cfbcc585f381a --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +er 54 103 5.536458438384996 3.0864903841329296e-08 29.17233009708738 87.61893203883496 1.3358083950399515 0.3757472714196316 13.465054065187209 8.223393744963309 2.0429537263872786 0.4010648005920765 1.4617958885025815e-28 0.0047018670886403 0.000396243947003 2.9657072025817963e-19 1.3471843804913178e-31 +vesicles 53 169 3.9694339985752185 7.204355840007004e-05 42.101941747572816 169.6626213592233 0.6789633151163722 0.6006686966705359 14.133870910307197 18.74575061031192 1.1351302778834993 0.3922666308151308 3.7339315622841913e-08 0.815619854466078 0.2312213207720306 3.035163569035868e-05 2.557931342352277e-10 +mitochondria 6 11 2.706339471371727 0.0068029463956664 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 1.5969584329828389e-07 0.0607401038440192 0.0002227826640135 2.7642156361586266e-07 7.777797134892854e-07 +golgi 19 61 2.694904279936796 0.007040885440319 15.631067961165048 61.19417475728155 0.6692399314943925 0.523533703348586 6.922582002252161 5.868805558877078 1.075539554450533 0.3729249549278102 0.0001179039643916 1.0 0.0714457353653021 0.0110026098329487 5.86166986223117e-06 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..df33877d745a194965578595bccf43f3dc9b652a --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 95.0 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7397f3c99493c671248ec9a43c7b3be61d662d30 --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..93782ed11bb4bc67918d1869bb1f69f184db7040 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +er 0.6491839143971343 5.536458438384996 3.0864903841329296e-08 5.247032357602667e-07 5.247033653195981e-07 103 Q9Y3E0,Q969Q5,Q9NQC3,O00767,Q8NHH9,Q969V3,Q9NTJ5,Q9Y487,Q9NPA0,Q15392,Q6NUK4,Q07065,Q99640,Q8NF37,O60499,Q9Y6K0,Q13190,O96005,Q96N66,P61019,Q9BRK0,Q14739,Q06136,O95470,Q15041,Q00765,Q8N4V1,Q9H6H4,P51572,Q96A33,O14735,P46977,Q16850,O15269,O75340,Q96HR9,Q9UM00,Q86Y07,Q9BVG9,Q8TCJ2,O95674,O14966,P49755,O75845,Q9Y5M8,Q15363,Q9P2W9,P61026,Q9NR31,O15173,P27824,Q86UL3,Q12981,O00264 54 +vesicles 0.4588228215335906 3.9694339985752185 7.204355840007004e-05 0.0012240348697009 0.0006123702464006 169 Q9Y3E0,O00767,Q969V3,Q15904,Q15392,Q8NF37,Q9UNK0,O60499,Q9Y6K0,O96005,P61019,Q06136,Q8IXU6,O95470,P41440,Q9C0E8,Q9H6H4,P13473,Q9Y371,O14735,O15269,P56589,P17302,Q9UM00,P11279,O95674,P30825,O14966,P49755,Q9H0U4,Q8IZ07,O75845,Q9H2J7,O14653,Q5VW38,P51798,P62820,Q15363,O15258,O15400,Q9H2V7,Q7Z3C6,Q93050,P61026,O43808,P31751,O15173,Q10713,P05023,Q86UL3,O95249,O00264,P49257 53 +mitochondria 0.8046174802431643 2.706339471371727 0.0068029463956664 0.1095650810628123 0.0213522821257524 11 Q969Q5,Q9NR31,Q9Y277,P45880,P21796,Q9NVH1 6 +golgi 0.4868821363733327 2.6949042799367957 0.007040885440319 0.1131845866161378 0.0213522821257524 61 Q9Y3E0,Q9NTJ5,Q9Y487,Q15904,Q13190,Q8IXU6,Q9Y371,O14735,Q9UM00,Q9H0U4,P49755,O14653,Q5VW38,P62820,O15258,Q8TAD4,Q7Z3C6,P61026,Q9NR31 19 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3c5f840f2e8d8a1c4dda7a5780f8938ccdc110e6 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AHCY", "AHSA1", "AKAP8L", "AKR1A1", "AKT2", "ALCAM", "ALDH9A1", "ANAPC16", 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"LIG1", "LMAN1", "LMNA", "LMNB1", "LNPK", "LPCAT1", "LSM14B", "LSS", "LTV1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MBOAT7", "MDH1", "MECP2", "MED14", "MED18", "MED21", "MED24", "MED4", "MFN1", "MFN2", "MIF", "MKI67", "MMGT1", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTOR", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO6", "NAF1", "NANS", "NAPA", "NAPG", "NCAPH", "NCKAP1", "NCL", "NCLN", "NECAP2", "NEK9", "NEMF", "NHP2", "NIFK", "NMD3", "NOL10", "NOL11", "NOM1", "NONO", "NOP10", "NOP2", "NOP53", "NOP58", "NPM1", "NSA2", "NSDHL", "NUCKS1", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP35", "NUP98", "NUTF2", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL11", "OSBPL8", "OXSR1", "PABPC4", "PACSIN2", "PACSIN3", "PAK1", "PAK2", "PAK4", "PARP1", "PBK", "PCNA", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PEX3", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHGDH", "PI4K2A", "PI4KA", "PICALM", "PIK3C2A", "PIN4", "PIP4K2A", "PIP4K2C", 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0.0198874102408346 +serine protease 8 19 2.040421979794826 0.0413083145567965 5.662621359223301 17.516990291262136 1.1445634795625386 0.1820139001244477 2.0809494011218104 1.6626107291843584 1.568325484830445 0.2384821649427795 0.116710745890471 0.2107016729382093 0.3746890061829235 0.0300192966842153 0.0859803679249299 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..815d5a5f527547e5672709ba0028dc98ab5b0103 --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 161, + "title": "Average number of proteins per term", + "value": 13.5527950310559 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e3ba8d77a2c08399c9351ffb9c2efbc32ce98d04 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3bf9a9398f33a5003d52ba6f111b26a547a2cbd0 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,45 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +transporter 0.5806792323030752 3.5222285991215836 0.0004279349615383 0.0665914401030832 0.0199925188247613 54 P41440,Q92544,P48739,P39210,Q99595,Q00169,Q12769,Q9NR77,O43681,P62072,Q9HD45,Q8N8Q8,O43615,Q567V2,Q15070,Q7Z3B4,Q9H2D1,Q9H2V7 18 +oxidoreductase 0.5913897541186367 3.473998429169033 0.0005127640356272 0.0792587092751467 0.0199925188247613 46 O43169,Q8N0U8,P00403,Q9Y6N5,O95298,O96000,O15254,Q9Y6M9,Q15067,O14949,O43396,P03915,Q8N4Q0,Q9Y320,O43676,Q9NX14,Q86Y39 17 +primary active transporter 0.6915531342293519 3.2435552879633596 0.001180478978201 0.1731809270685665 0.0237571394362963 26 Q96NB2,P23634,Q9H2J7,O75381,O96008,Q9GZP9,P05023,Q6P4A7,Q9NS69,Q6NTF9,Q8N4H5,Q9H9B4,P20020,P98194,P16615 15 +secondary carrier transporter 0.7371700449525078 3.097276143781422 0.0019530784442465 0.2700309174588483 0.0285859663203355 17 Q9H936,Q8WWI5,Q9UBX3,Q9BQT8,O14975,Q9UJS0,Q02978,Q8TB61,Q96ES6,Q9Y6M7,O95202,Q9BXP2,Q15043 13 +mitochondrial carrier protein 0.8611757533495401 2.720375772826328 0.0065207767992394 0.6512091850190611 0.061755592039856 8 Q9BSK2,Q9HC21,Q86VD7,Q9NZJ7,Q70HW3,Q9Y6C9 6 +glycosyltransferase 0.5938002144944599 2.6178662201110483 0.0088481486490628 0.7609043697525164 0.077280774917113 27 Q9H3H5,Q8NBN7,Q9H0U3,Q9BT22,Q8N4A0,Q10469,Q9BV10,P46977,Q16739,Q8TCJ2,Q10472 11 +transferase 0.5314318664078351 2.5016570812655594 0.0123613592035398 0.8650136757092786 0.0947704205604723 33 P43490,Q99735,Q8NCH0,P37268,Q11206,Q9Y6K0,Q9BVG9,O95674,Q7LGA3 9 +oxygenase 0.8652221375857725 2.4746647074952244 0.0133361311630471 0.8848549696700836 0.0975962326022992 7 P09601,Q6UW02,Q14534,P30519 4 +membrane traffic protein 0.4486592253055208 2.300671401072164 0.0214102117933361 0.9693303091585314 0.1327885583344338 62 P40855,Q00765,P43307,Q9H6H4,P51572,Q96PC5,O60313,Q8N2H4,Q9NX40,Q6NUK4,Q13432,Q9BRK0,P49257 13 +transfer/carrier protein 0.7388497264949782 2.2899269297440616 0.0220255528363706 0.9722841172669444 0.1327885583344338 10 P12236,P12235,Q9Y5M8,Q5T8D3,P17900,O14828 6 +acyltransferase 0.5618856388330276 2.190457853002887 0.0284910482531981 0.9904734451460804 0.1479696377020936 23 P14324,P49356,P53611,P35610,Q9HCL2,Q86UL3,Q8NF37,P23786,O15228,P50416,P49354,Q92604 12 +ATP synthase 0.5715089374275354 2.17350733562849 0.0297421543133797 0.9922583545584106 0.1491783723360285 21 Q93050,P00846,O75964,P56385,Q9Y487,P24539,P36542,Q96IX5 8 +oxidase 0.6412075957091888 2.142674493144937 0.0321392448985409 0.994801551504821 0.1507498758193635 14 Q15800,O75845,P13073,O43819,P36551,O75880 6 +serine protease 0.5624878743983872 2.040421979794826 0.0413083145567965 0.9988771733967896 0.1750168064116904 19 P67812,O14773,P10619,Q4J6C6,Q9HB40,P42785,Q8N2K0,Q9H300 8 +voltage-gated ion channel 0.9843505477308296 1.9450560936730248 0.0517682274853088 0.9998080292716862 0.1986908326316819 3 Q9Y277,P45880 2 +SNARE protein 0.6381520251316399 1.9236251782313183 0.0544015827278923 0.9998773169410006 0.2031505394968589 12 O14653,Q9UNK0,O95249,O60499,Q9P2W9,O15400 6 +transmembrane signal receptor 0.7334305935129706 1.8674995633365716 0.0618318577436032 0.9999655499625858 0.2121455651773573 7 O00264,O15173 2 +lipase 0.8570932411452012 1.8372139868927144 0.0661783116492005 0.9999836883845606 0.2174430239902302 4 Q8NCG7,Q9H6V9 2 +amino acid transporter 0.8128108768165458 1.8005639560037685 0.0717716345813948 0.9999937994736858 0.2265731993647953 5 P30825,O14925,Q96QD8 3 +membrane trafficking regulatory protein 0.5273361139877245 1.7701636139503718 0.0766998888176664 0.9999973684904824 0.2374746557623903 18 O43760,P13473,P24390,Q14108,Q8WTV0,P11279 6 +G-protein coupled receptor 0.9215052643637196 1.6954056459935938 0.0899984956070023 0.9999997454460994 0.2634501416859523 3 Q5VW38 1 +ion channel 0.6937804592928888 1.6768497457988336 0.0935718672677743 0.999999864894331 0.2690191183948512 7 Q96S66,Q9C0H2,P51790 3 +ATP-binding cassette (ABC) transporter 0.6289515923630945 1.644515598900978 0.1000697448650853 0.9999999575746632 0.273492405767354 9 P28288,P08183,Q9NUT2,O75027,Q03519,O14678,P33527 7 +phospholipase 0.6769055461920066 1.3788586954048778 0.1679383254037096 0.9999999999998604 0.382197686100663 6 Q8IV08,Q8N2A8,Q9Y6Y8 3 +kinase 0.4622991179301915 1.3102957548002314 0.1900958030384727 0.9999999999999982 0.4135868147188393 18 Q9BRR6,P35790,Q53H12,P52789,Q8WVC6 5 +calmodulin-related 0.4900182491007859 1.2996026321178442 0.193737197099779 0.9999999999999992 0.4144894476115504 15 Q9BPX6,Q14257,Q9BRK5,Q02818,P80303 5 +methyltransferase 0.4944925798069385 1.2387954091406237 0.2154212744789834 1.0 0.4287810521180482 14 Q9BV86,Q6UX53,Q86VU5,P21964 4 +metalloprotease 0.4311627752679154 1.230627983282958 0.2184620342399019 1.0 0.4287810521180482 24 Q6P179,P42892,Q9UIQ6,Q10713,O75844,Q7Z2K6,Q9NZ08,Q9Y4W6,Q9NQH7 9 +lyase 0.4745766579298669 1.1108091650376064 0.2666505006421076 1.0 0.4878492114020377 14 P53701,Q9UHG3 2 +protein modifying enzyme 0.3818977068546029 0.9177524891614328 0.3587484609136688 1.0 0.5607621573504921 27 P50897,Q86X55,P51812,Q86YN1,O60725,O15460,Q92791,Q12797,O75718 9 +galactosidase 0.6292240300375381 0.7485847130546435 0.4541075487741253 1.0 0.6357505682837754 2 P06280 1 +tubulin 0.5912913348262101 0.7138479744784358 0.4753211905986509 1.0 0.6597130317791621 4 Q9BUF5,Q13885 2 +cytoskeletal protein 0.5148616661971215 0.6273173382472982 0.5304512404000841 1.0 0.7058070223505251 6 P27105,Q16181 2 +nucleotide phosphatase 0.4805990295789628 0.4780222952539292 0.6326343365523865 1.0 0.7791615561800475 6 P49902,Q9H857 2 +heterotrimeric G-protein 0.4196693681717207 0.4761378502417048 0.6339761730409081 1.0 0.7791615561800475 8 Q8NHH9 1 +major histocompatibility complex protein 0.5972557933451974 0.4363467198886537 0.6625851895109509 1.0 0.8020768083553617 3 P04439 1 +tight junction 0.504693366708373 0.2916226280570496 0.7705751724197807 1.0 0.8861209932654103 2 Q9UDY2 1 +reductase 0.2953926652702375 0.2875596938950147 0.7736838017822114 1.0 0.8861209932654103 31 Q15392,Q9UDW1,P04035,Q14739,Q06136 5 +chaperone 0.2703971662540998 0.2220215409301656 0.8242971145465612 1.0 0.9116465076400396 71 O14657,Q9Y2R0,Q9Y2G8,Q9NWM8,Q7KZN9,Q96KC8,Q96JJ7,Q9Y680,O15260,Q9NVH1 10 +phosphatase 0.3155227641591561 0.2148654930594712 0.8298721890751695 1.0 0.9116465076400396 16 Q9NTJ5,Q9NPH0,Q9NX62 3 +viral or transposable element protein 0.4755944931163809 0.2116592285594132 0.832372898280036 1.0 0.9116465076400396 2 Q9NUD5 1 +vesicle coat protein 0.2885431689450439 0.1480862051128719 0.8822747361351388 1.0 0.9407035266076648 27 Q9Y3B3,Q9BVK6,Q9Y3A6,P49755 4 +homeodomain transcription factor 0.4744913928012615 0.1130261265306512 0.9100098419566448 1.0 0.9638920036514462 3 O94776,Q13330 2 +decarboxylase 0.4012542236959682 0.0881917372952901 0.929724284412152 1.0 0.9783373188912188 4 Q9UG56 1 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..eb9f6808e1b858d744f00cc1544531e7154469b0 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "amylase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "gap junction", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG5", "ALKBH5", "AMFR", "ANAPC1", "ANAPC7", "ANKFY1", "ANKRD17", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APRT", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP5", "ARHGDIA", "ARHGEF7", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6", "ARL6IP5", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD5", "ATG3", "ATG4B", "ATL2", "ATL3", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1H", "ATP8", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAG6", "BAIAP2", "BAP18", "BCAP31", "BCAS2", "BCKDHB", "BCLAF1", "BET1", "BLMH", "BLOC1S1", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CBL", "CBR1", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDS2", "CEBPZ", "CEP170", "CEPT1", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNP", "COA3", "COASY", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC27", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDT", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPAGT1", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC10", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC4", "EXOC5", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GIPC1", "GJA1", "GLA", "GLB1", "GLDC", "GLE1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACL1", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGCR", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HTRA2", "HUWE1", "IARS", "IARS2", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "ISG20L2", "ISOC1", "ISY1", "ISYNA1", "ITGB1", "ITPA", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LENG8", "LETM1", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTN1", "LYAR", "LYPLA1", "MACF1", "MAGED2", "MAGT1", "MALT1", "MAN1A1", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME2", "MECP2", "MED14", "MED18", "MED21", "MED23", "MED24", "MED4", "METTL1", "METTL3", "METTL7B", "MFSD3", "MFSD5", "MGAT2", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIPEP", "MKRN2", "MMAB", "MMS19", "MOCS3", "MOGS", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTCH2", "MTFMT", "MTHFS", "MTMR14", "MTOR", "MTPAP", "MTSS1L", "MUT", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCBP1", "NCDN", "NCEH1", "NCKIPSD", "NCOA5", "NCOR1", "ND1", "ND5", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NEDD4L", "NENF", "NF1", "NFRKB", "NFS1", "NHP2", "NIP7", "NIPBL", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NRDC", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "OTUB1", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PARG", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF3", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIK3C2A", "PIK3R4", "PIN1", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP3", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POR", "PPA1", "PPAN", "PPAT", "PPCDC", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABAC1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RAD23B", "RAD51C", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RARS", "RARS2", "RAVER1", "RB1", "RBL1", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBM47", "RBM7", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REEP6", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIPK1", "RNASEH2A", "RNF2", "RNMT", "RNPS1", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC35B2", "SLC38A2", "SLC39A14", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP47", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX19", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPNS1", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "ST3GAL4", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STK4", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT3H", "SUPT6H", 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sha256:25e210b68738d37185a96dcd4870f530e407471b5972c60dfce8aa85ddcf0783 +size 131389 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0763f31eb55360da491ddebc2605ba796d99a5d0 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a6aa78ec130ab0baff8e783efa45b45061d1c90547f7cf4a6fa210ab261a9e1e +size 497828 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..39d3309b8322325ca1f9271c723fe775fc845a00 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,15 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transporter 86 195 5.773066583897782 7.784166344329127e-09 57.59466019417476 188.27912621359224 1.4971900036635353 0.4160578104205245 21.77919356765414 18.57070590158326 1.926868489654782 0.421013047757716 3.385611314647568e-16 0.6875568576479667 0.0022102619070441 7.043206632578458e-07 4.3909821353945656e-18 +SLC superfamily of solute carriers 40 48 4.597751338699479 4.270752739010675e-06 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 1.0568426671938044e-07 1.0 0.007702425165207 0.0015134478882563 4.3757408113778704e-08 +SLC25 family of mitochondrial transporters 20 22 3.3235937464574183 0.0008886554871001 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 6.457012294694573e-09 1.0 0.0003996291666218 2.4238306634181277e-05 6.779498233654895e-10 +Receptor 10 28 2.88591240902237 0.0039028075875284 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.0072510382594308 0.4014813083941581 0.2673507529215621 0.0140990291270638 0.0130862744441739 +Mitochondrial nucleotide transporter subfamily 9 10 2.829676861131577 0.0046595038718744 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 2.1701908599228163e-08 1.0 0.0086772133501052 0.000366006536683 1.5115415915239908e-10 +Glycosyltransferase 12 21 2.68880057592782 0.007170924475587 5.713592233009709 16.264563106796118 0.58827010515732 0.444796659838118 2.8207810163966904 2.842193627279741 1.1276277753027448 0.3350616775048655 0.0026179887515657 0.2624522374738631 0.453417077782931 0.0652678486609716 0.0001858532328021 +Signaling 5 18 2.408060991975903 0.0160375014811822 5.66747572815534 18.009708737864077 1.330299096012152 0.2668377480945127 2.507969905227609 1.6994867622232877 1.0107551340834326 0.2926688105318188 0.12030337719098 1.0 1.0 0.3571368988977866 0.2507340366621381 +Acyltransferase 8 12 2.350162423527024 0.0187652205685027 3.1067961165048543 9.41504854368932 0.3809422525127639 0.5105103319247358 1.8677779818542355 1.784525377484509 0.9351567129762406 0.3147395520597634 0.1136831966124214 1.0 1.0 0.1713585638073601 0.0601547876346515 +Ion channel 5 11 2.3093364633624005 0.0209249177570762 2.9611650485436893 8.271844660194175 0.2358363301857469 0.3871382019519256 1.7759030526384678 1.9242659665051836 1.1979225459677625 0.2963208074862355 0.0980183809574614 1.0 0.356411341728891 0.3051232152156647 0.0222888543246737 +Oxidase 10 20 2.3036975327124853 0.0212396284448384 6.703883495145631 19.237864077669904 1.0247065178117305 0.263154064152295 3.1321515397534676 1.9967748999180144 1.3264616190823058 0.2799417791483025 2.552747786677986e-05 0.0108643857486399 0.0390718495583504 0.0444854600227105 1.7993855091680245e-05 +P-type ATPases 4 8 2.126849476411096 0.0334325918887423 3.2815533980582523 6.757281553398058 0.5021561418998097 0.3946150755400491 1.82441625577419 1.518277124105495 1.19746001211325 0.3286800838620415 0.204933269580831 1.0 0.1898352204968973 0.4160065505344545 0.0871448534539997 +F-type and V-type ATPases 6 16 2.101344443303476 0.0356107410553201 4.995145631067961 15.616504854368932 0.6819760311565471 0.3553057475304781 2.5561606009064737 1.187932616128487 1.149561543758102 0.2999604229905949 1.6357068079897842e-05 1.0 1.0 0.0172025832638257 7.282417182293456e-05 +F-type ATPase 4 9 1.997456378195572 0.0457756286289983 3.174757281553398 7.754854368932039 0.3978961134348252 0.300656405601223 2.006916121747128 0.8649601417133376 1.341428125637103 0.2766885427231999 3.0471225926664624e-05 1.0 1.0 0.0276231155809849 9.296084487717995e-05 +SNARE protein 6 11 1.9731358702697577 0.0484800844775812 4.555825242718447 10.6626213592233 0.9494792984446184 0.3117420251981136 2.5225757464631977 2.583604188764985 1.1633177546874711 0.3031193116521645 0.0184273216152928 1.0 0.0269433955752302 0.0037492480554313 0.0085681988325283 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..0b80b0c82cc7cb704e11dfccc38ed0c651facec8 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 2040, + "title": "Average number of proteins per term", + "value": 3.132843137254902 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..46f39d3d116fde04e718c94a3af29cb94a7d7a0e --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5ac55f781ad868834a35a2dfca78bf6b053babc4 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,63 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter 0.5729813485468631 5.773066583897782 7.784166344329127e-09 1.5879573324517295e-05 1.587969934447142e-05 195 Q8TBP6,P24390,Q9UNK0,Q13190,Q7Z3B4,Q8WWI5,O43760,P13473,Q86VD7,Q9H2D1,P20020,Q9H936,Q9UBX3,P23634,O14653,O75027,Q9P2W9,Q9NZJ7,Q15070,Q9H9B4,Q8TAD4,O95563,Q9H2V7,P16615,Q9Y5J6,Q93050,P00846,O43731,P36542,Q9Y6C9,Q6NUK4,O60499,Q9HC21,Q9BRK0,Q9H6H4,Q8N2H4,Q96ES6,Q9HD45,Q70HW3,P17900,P30825,Q96QD8,Q9Y3A6,Q8TB61,O95249,Q92544,Q9Y487,Q9BVK6,Q9Y3B3,Q7L0J3,P41440,Q00765,P08183,P51572,P12235,P24539,P98194,P11279,P49755,Q9BQT8,Q9H2J7,Q9BSK2,P56385,Q03519,Q15043,Q6NUK1,O43808,O96008,Q9H0U3,P56134,Q9Y6M7,P49257,Q96NB2,Q00169,P12236,O95202,Q8IXU6,P48739,Q96HR9,O14678,Q12769,P61619,Q15363,O15400,P05141,P05023 86 +SLC superfamily of solute carriers 0.7164796645106823 4.597751338699479 4.270752739010675e-06 0.0086745116130312 0.0029041118625279 48 Q96NB2,Q00325,Q8TBP6,P12236,P14672,O95202,Q9HC21,Q8IXU6,Q7L0J3,P41440,Q8WWI5,Q02978,P12235,Q70HW3,Q86VD7,Q9H2D1,P30825,Q9H936,Q9BQT8,Q9UBX3,Q9H2J7,Q9BSK2,Q15043,Q9BXP2,Q9NZJ7,Q6NUK1,Q9H9B4,Q8TAD4,O95563,Q9H2V7,Q96QD8,O43808,O14975,Q9UJS0,Q9H0U3,Q8TB61,P05141,Q9Y6M7,O75746,Q9Y6C9 40 +SLC25 family of mitochondrial transporters 0.7399345695769532 3.3235937464574183 0.0008886554871001 0.8369442600843315 0.0128428021063334 22 Q00325,Q8TBP6,P12236,Q9HC21,Q02978,P12235,Q70HW3,Q86VD7,Q9H2D1,Q9H936,Q9BQT8,Q9UBX3,Q9BSK2,Q9NZJ7,Q6NUK1,O43808,Q9UJS0,P05141,O75746,Q9Y6C9 20 +Receptor 0.6221699725685849 2.88591240902237 0.0039028075875284 0.9996568368495362 0.0179318186454011 28 P39210,Q9GZP9,Q9NR77,Q13432,Q13641,Q6NTF9,P57105,Q14108,Q567V2,Q8WTV0 10 +Mitochondrial nucleotide transporter subfamily 0.8484943538268431 2.8296768611315772 0.0046595038718744 0.9999271859863574 0.0198442336088179 10 O43808,Q9BSK2,P12236,P12235,Q9HC21,Q70HW3,Q86VD7,Q6NUK1,Q9H2D1 9 +Glycosyltransferase 0.6479656006963865 2.68880057592782 0.007170924475587 0.9999995793180004 0.0255489926165528 21 Q9H3H5,Q93063,Q9BT22,Q8N4A0,P15291,Q10469,Q9BV10,P46977,Q16739,Q8N128,Q8TCJ2,Q10472 12 +Signaling 0.6229278006194847 2.408060991975903 0.0160375014811822 0.9999999999999952 0.0430480302915943 18 P43490,Q07820,Q96PC5,O15173,O00264 5 +Acyltransferase 0.7157683982292047 2.3501624235270233 0.0187652205685027 1.0 0.0481522641003088 12 P14324,Q86SQ9,P49356,P53611,P35610,Q86UL3,Q8NF37,P49354 8 +Ion channel 0.7266357929171002 2.3093364633624005 0.0209249177570762 1.0 0.0519304528277805 11 P51790,Q96RD7,Q96S66,Q4KMQ2,Q9C0H2 5 +Oxidase 0.5961995804729063 2.3036975327124853 0.0212396284448384 1.0 0.0524428985335724 20 O43169,Q15800,O75845,O15254,O43819,Q15067,Q709F0,P36551,O15260,O75880 10 +Miscellaneous SLC25 mitochondrial transporters 0.9608886107634538 2.2180353635465284 0.0265524213027785 1.0 0.0619050736659066 2 Q9NZJ7 1 +P-type ATPases 0.7363194529591569 2.126849476411096 0.0334325918887423 1.0 0.0727631109197305 8 P20020,P98194,P05023,P16615 4 +F-type and V-type ATPases 0.5965526575116652 2.1013444433034754 0.0356107410553201 1.0 0.0761487544579172 16 Q93050,P00846,P56385,Q9Y487,P24539,P36542 6 +F-type ATPase 0.6964696271109906 1.9974563781955716 0.0457756286289983 1.0 0.0920022486730606 9 P56385,P24539,P36542,P00846 4 +SNARE protein 0.6634571445530655 1.9731358702697577 0.0484800844775812 1.0 0.095925676366892 11 O14653,Q9UNK0,O95249,O60499,Q9P2W9,O15400 6 +Serine protease 0.4882281040437126 1.854297292043911 0.0636966393358997 1.0 0.1174874721927988 28 P67812,O14773,Q9Y6M1,P10619,P42785,Q9HB40,Q92945,P61978,Q8N2K0,Q9H300 10 +SLC35 family of nucleotide sugar transporters 0.8714017521902429 1.8247928859407412 0.0680322898230898 1.0 0.123037119892822 2 Q8TB61 1 +Chloride channel family 0.8585732165206508 1.7675811159203498 0.077130957294053 1.0 0.1347714300879102 2 P51790 1 +Oxidoreductase 0.3464467388490783 1.75213216240895 0.0797510850376124 1.0 0.1381088399632677 118 O43169,O95298,Q15392,Q9Y6M9,Q15067,Q9H7Z7,Q14739,P03886,Q13423,Q15800,Q8N0U8,P00403,Q16850,Q9P0J0,Q9NZ01,O75845,Q14534,O15254,P03915,Q709F0,Q8N4Q0,P21912,Q8TED1,Q9UDW1,Q9NX14,O15260,O75880 27 +ATP-binding cassette transporter family 0.7016609213412894 1.7150157960614991 0.0863423308919626 1.0 0.1460517039963547 7 P28288,P08183,Q9NUT2,O75027,Q03519,P33527 6 +Ca2+-ATPases 0.8193487789605445 1.6793984097082 0.0930744230265139 1.0 0.1543673357512913 4 P20020,P98194,P16615 3 +SLC56 Sideroflexins 0.8119524405506864 1.5583981445510264 0.1191388962034911 1.0 0.1844031473862837 2 Q96NB2 1 +Protease 0.3276205259368106 1.462540183881213 0.143593241085379 1.0 0.212395119577068 105 P67812,Q9UIQ6,P55786,Q9HB40,Q8N2K0,Q6P179,Q70CQ2,O75844,P51784,Q7Z2K6,Q9NZ08,Q9H300,Q9Y4W6,Q7L5N1,Q92643,O00487,P42892,O14773,Q9Y6M1,P10619,Q92905,Q10713,P42785,Q92945,Q13510,P53634 26 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.7557921102066234 1.4099564723843372 0.158552536005323 1.0 0.2266090908410545 4 Q9BQT8,Q02978,Q9UBX3 3 +Methyltransferase 0.4884474129442401 1.3875536784215374 0.1652729949674487 1.0 0.2331652211159027 16 P04818,Q86VU5,Q08J23,P21964,Q9BV86,Q6UX53 6 +Transferase 0.3184148706924489 1.36436129355732 0.1724538836738256 1.0 0.2403045920045111 141 P14324,Q9H3H5,Q9Y679,Q13126,Q93063,Q08J23,Q8N4A0,Q10469,Q9BV10,Q8NF37,P25325,Q9Y6K0,Q96N66,P49356,P35610,P46977,O15269,Q9BV86,Q9BVG9,Q8TCJ2,Q86SQ9,P04818,Q86VU5,Q8NCH0,Q9BT22,Q8N128,P23786,O14828,Q6UX53,Q99735,P53611,P15291,Q16739,P21964,Q86UL3,P50416,P49354,O00411,Q10472 39 +Calcium-binding protein 0.4601448409662304 1.339066029753001 0.1805491781419397 1.0 0.2485052553377636 20 P43307,Q9BPX6,Q14257,Q9BRK5,Q02818,P80303 6 +CDK family 0.6213650764995424 1.3206191183720095 0.1866283948625775 1.0 0.2543232635401858 7 P11802,Q00535,P50750,Q00534 4 +ABCB subfamily 0.7012214218602958 1.3103813991923097 0.1900668429447973 1.0 0.2572902187175757 5 Q9NUT2,O75027,P08183,Q03519 4 +Extracellular structure 0.5758173638894881 1.3017278709495923 0.1930094284596148 1.0 0.2595512419628308 8 Q92791,Q32P28 2 +Nucleotide phosphatase 0.5682819479051899 1.2615722737647528 0.2071027382252537 1.0 0.2743438869996867 8 P49902,O43681,Q8IWA4 3 +Oxygenase 0.6739285847228735 1.1888142849389824 0.2345127555098409 1.0 0.2998250698045741 5 Q14534 1 +Intracellular calcium-sensing protein 0.4381503011042339 1.1368461001911685 0.2556026277161116 1.0 0.3187221030200903 17 Q9BPX6,Q14257,Q9BRK5,Q02818,P80303 5 +Calmodulin 0.4381503011042339 1.1368461001911685 0.2556026277161116 1.0 0.3187221030200903 17 Q9BPX6,Q14257,Q9BRK5,Q02818,P80303 5 +CDK4 subfamily 0.7155819774718517 1.1245381947061492 0.2607847766226883 1.0 0.3234048293679538 2 P11802 1 +Reductase 0.4499866497379772 1.1224935759336958 0.2616526374395103 1.0 0.324087055480632 16 Q14739,Q15392,Q9H7Z7,Q9UDW1 4 +SLC4 family of bicarbonate transporters 0.7124530663329407 1.1105670460706571 0.2667547539737471 1.0 0.3276393211865054 2 Q9Y6M7 1 +Membrane trafficking regulatory protein 0.4284544424187586 1.0644974985335798 0.2871033869918475 1.0 0.3447268448872095 18 O43731,O43760,P13473,P24390,P55735,P11279 6 +Metalloprotease 0.358690992483781 1.0430566587773125 0.296922052325463 1.0 0.3523682296358025 37 Q6P179,P42892,Q9UIQ6,Q7L5N1,Q10713,O75844,Q92905,Q7Z2K6,Q9NZ08,O00487,Q9Y4W6 11 +Phospholipase 0.6445081829607888 0.935046572248139 0.3497642988174498 1.0 0.39684047251813 4 Q8N2A8 1 +Phosphatase inhibitor 0.519841431690338 0.8136527326826396 0.4158439195241121 1.0 0.4455470566329773 7 Q01105,P55209 2 +Phosphatase 0.3469451084758531 0.7537866954019696 0.4509773141906781 1.0 0.4717916517687093 31 P49902,Q9H857,Q86YN1,P11117,O43681,Q9NPH0,Q9NX62,Q8IWA4 8 +Mitochondrial amino acid transporter subfamily 0.5745341103304702 0.7501919300442622 0.4531391184324636 1.0 0.472840819233875 5 Q9H936,Q8TBP6,Q9UJS0 3 +Tubulin 0.5912913348262101 0.7138479744784358 0.4753211905986509 1.0 0.4931989572118729 4 Q9BUF5,Q13885 2 +Na+/K+-ATPases 0.6748671116452709 0.7120410287959736 0.4764393697458577 1.0 0.4938700783950964 3 P05023 1 +Unclassified protein 0.3779434191932316 0.7066792206493535 0.479765845521547 1.0 0.4970656804794087 19 Q9BRR6 1 +CDK1 subfamily 0.6063829787234067 0.6545621163305284 0.5127497218383559 1.0 0.530699864307583 2 P06493 1 +V-type ATPase 0.4758334495410757 0.5990625620180506 0.549131165940755 1.0 0.5669167907485527 7 Q93050 1 +Atypical group 0.5619069985896594 0.5962582469258406 0.5510027193617737 1.0 0.5685612278695085 4 Q15118 1 +Lipase 0.5042711474717403 0.5803932656509074 0.5616494454670724 1.0 0.5789615304460979 6 Q8N2A8,Q6PIU2 2 +Lyase 0.3469353526392899 0.4803002656296021 0.6310139000240982 1.0 0.6471937436144597 19 O96005,P53701,Q96KA5,P22830 4 +Heterotrimeric G-protein 0.4196693681717207 0.4761378502417048 0.6339761730409081 1.0 0.6492527073310506 8 Q8NHH9 1 +HDAC class I 0.5397371714643182 0.4038465260483777 0.6863255808002564 1.0 0.7004022935630431 2 Q13547 1 +Vesicle coat protein 0.315312539918743 0.3061450225845434 0.7594942294582818 1.0 0.7700637316575024 24 Q9Y3B3,Q9BVK6,Q9Y3A6,P49755 4 +Phosphatase modulator 0.3724026349082888 0.2971794439446085 0.7663295146925233 1.0 0.7766081519983843 10 Q01105,Q99733,P55209 3 +Tight junction 0.504693366708373 0.2916226280570496 0.7705751724197807 1.0 0.7801356584299516 2 Q9UDY2 1 +PIKK family 0.4799749687108741 0.2228643575357164 0.823641077296499 1.0 0.8317959394479495 2 P42345 1 +Growth factor 0.4333518304492859 0.2071551076956354 0.8358887256610283 1.0 0.8433298715867942 5 Q96PC5 1 +Guanyl-nucleotide exchange factor 0.4396120150187627 0.1313963067498506 0.895461810121283 1.0 0.902986699281966 2 Q96N67 1 +PAKA subfamily 0.4349186483103756 0.1225024422140202 0.9025011119541118 1.0 0.9096355080960414 2 Q13153 1 +AGC group 0.323400852470909 0.0560486207180876 0.9553030742761386 1.0 0.961429833015946 8 P31751 1 +Deaminase 0.365998747651844 0.0238974549318557 0.9809344043745916 1.0 0.9857665935587028 4 P55265,P08397,P00813 3 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..75a5cbf05fed253355b01415ad43b75036143918 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1,4-alpha-glucan-branching enzyme", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L23, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L9, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-formyltetrahydrofolate cyclo-ligase", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase protein 8", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase WRNIP1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 2/3 complex subunit 5", "Actin-related protein 3", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Adenylyltransferase and sulfurtransferase MOCS3", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amylase", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Ankyrin repeat and SAM domain-containing protein 1A", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atlastin-3", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase a", "B-cell receptor-associated protein 31", "BET1 homolog", "BTB/POZ domain-containing protein KCTD12", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-1,4-galactosyltransferase 1", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biogenesis of lysosome-related organelles complex 1 subunit 1", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 2", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit delta", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-2", "Catechol O-methyltransferase", "Catechol O-methyltransferase domain-containing protein 1", "Catenin alpha-1", "Catenin delta-1", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline transporter-like protein 1", "Choline/ethanolamine kinase family", "Choline/ethanolaminephosphotransferase 1", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 2", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collagen type IV alpha-3-binding protein", "Collectin-12", "Condensin complex subunit 1", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4A", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cyclase", "Cyclin-K", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DCK/DGK family", "DDB1- and CUL4-associated factor 13", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA polymerase subunit gamma-1", "DNA primase small subunit", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrodolichyl diphosphate synthase complex subunit DHDDS", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidylate deaminase", "Deoxyguanosine kinase, mitochondrial", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydroorotate dehydrogenase (quinone), mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 4", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 2", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dystonin", "Dystroglycan", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D1", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exostosin-2", "Exportin-1", "Exportin-2", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Folate transporter 1", "Forkhead box protein C1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GDP-L-fucose synthase", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GPN-loop GTPase 1", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Gamma-tubulin complex component 4", "Gamma-tubulin complex component 5", "Ganglioside GM2 activator", "Gap junction", "Gap junction alpha-1 protein", "Gap junction-forming innexin (innexin) family", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIH subunit 1", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Geranylgeranyl transferase type-2 subunit beta", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD2", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin superfamily cell adhesion molecule", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of growth protein 5", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inorganic pyrophosphatase", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "JAKA family", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kinetochore protein NDC80 homolog", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Leukocyte elastase inhibitor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Low density lipoprotein receptor adapter protein 1", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MST subfamily", "MTSS1-like protein", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membralin", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Metastasis-associated protein MTA3", "Methionine--tRNA ligase, mitochondrial", "Methionyl-tRNA formyltransferase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7B", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1B", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial coenzyme A transporter SLC25A42", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim10 B", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase kinase kinase 7", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Mucosa-associated lymphoid tissue lymphoma translocation protein 1", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] 1 subunit C2", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADH-ubiquinone oxidoreductase chain 5", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurofibromin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral amino acid transporter subfamily", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear factor related to kappa-B-binding protein", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 5", "Nuclear receptor corepressor 1", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin GLE1", "Nucleoporin Nup37", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "Obg-like ATPase 1", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Other-UNIQUE family", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PDZ domain-containing protein GIPC1", "PEK family", "PH-interacting protein", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PIN2/TERF1-interacting telomerase inhibitor 1", "PKA family", "PKC alpha subfamily", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pannexin-1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal carnitine O-octanoyltransferase", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylated adapter RNA export protein", "Phosphoserine phosphatase", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Platelet-activating factor acetylhydrolase 2, cytoplasmic", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polypeptide N-acetylgalactosaminyltransferase 4", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA cleavage complex 2 protein Pcf11", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 39", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Prenylated Rab acceptor protein 1", "Presenilins-associated rhomboid-like protein, mitochondrial", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable asparagine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable histidine--tRNA ligase, mitochondrial", "Probable leucine--tRNA ligase, mitochondrial", "Probable serine carboxypeptidase CPVL", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein ABHD16A", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein LSM14 homolog B", "Protein Mpv17", "Protein NDRG3", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SEC13 homolog", "Protein SET", "Protein SYS1 homolog", "Protein Wiz", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c alpha type", "Protein kinase c delta type", "Protein methyltransferase", "Protein o-mannose kinase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec24D", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxine kinase family", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA polymerase II subunit A C-terminal domain phosphatase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein 7", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein with serine-rich domain 1", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Ras-related protein Ral-B", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 2", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor expression-enhancing protein 6", "Receptor-interacting serine/threonine-protein kinase 1", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinoblastoma-associated protein", "Retinoblastoma-like protein 1", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 1", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC44 choline transporter-like family", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC6 neurotransmitter transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRPK family", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "Sarcolemmal membrane-associated protein", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 3", "Selenide, water dikinase 1", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 2", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent HCO3- transporters", "Sodium-dependent neutral amino acid transporter B(0)AT2", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 4", "Solute carrier family 25 member 33", "Solute carrier family 25 member 40", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sortilin", "Sorting nexin-1", "Sorting nexin-19", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 47", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TAK1 subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "TK group", "TKL group", "TNF receptor-associated factor 2", "TOPK family", "TRIO family", "TTK family", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Tmem38 family", "Torsin-1A", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor SPT20 homolog", "Transcription initiation factor IIB", "Transcription initiation factor IIE subunit beta", "Transcription initiation protein SPT3 homolog", "Transcriptional activator protein Pur-alpha", "Transcriptional enhancer factor TEF-1", "Transcriptional repressor CTCF", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 4", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Triple functional domain protein", "Trophoblast glycoprotein", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-4A chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase jak1", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "U6 snRNA-associated Sm-like protein LSm8", "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 34", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VIP36-like protein", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 4B", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "YEATS domain-containing protein 2", "YEATS domain-containing protein 4", "YLP motif-containing protein 1", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger RNA-binding protein", "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger transcription factor", "Zinc transporter 5", "Zinc transporter ZIP14", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-decapping enzyme 1A", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD16A", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR1A", "ACTR2", "ACTR3", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "ANAPC1", "ANKS1A", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "ARCN1", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1H", "ATP8", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "B4GALT1", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCKDHB", "BCLAF1", "BET1", "BLMH", "BLOC1S1", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CBL", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC20", "CDC37", "CDC40", "CDC42", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CEBPZ", "CEP170", "CEPT1", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNP", "COASY", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DAD1", "DAG1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DDAH2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DERL2", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIS3", "DLD", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPAGT1", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENO2", "EPHA7", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERH", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC1", "EXOC4", "EXOC5", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP4", "FKBP5", "FMR1", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GCAT", "GCLC", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GIPC1", "GJA1", "GLB1", "GLDC", "GLE1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GOSR2", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2E2", "GTF2H1", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "ING5", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITGB1", "ITPA", "IVD", "JAK1", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMB1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLRAP1", "LETM1", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LTN1", "MACF1", "MAGED2", "MAGT1", "MALT1", "MAN1A1", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARCH5", "MARS2", "MAT2A", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDH1", "MDH2", "ME2", "MECP2", "MED14", "MED21", "METTL1", "METTL7B", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGAT2", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MOCS3", "MORF4L1", "MORF4L2", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL38", "MRPL39", "MRPL44", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS16", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTA3", "MTAP", "MTCH1", "MTCH2", "MTFMT", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTOR", "MTPAP", "MTSS1L", "MUT", "MYBBP1A", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NARS2", "NBN", "NCAPD2", "NCBP1", "NCEH1", "NCL", "NCOA5", "NCOR1", "ND1", "ND5", "NDC80", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS7", "NDUFS8", "NEDD4L", "NEK9", "NF1", "NFRKB", "NFS1", "NHP2", "NIPBL", "NKRF", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NRDC", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCRL", "OLA1", "OPA1", "ORC2", "ORC3", "OTUB1", "OXA1L", "OXSR1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAFAH2", "PAICS", "PAK1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCMT1", "PCNA", "PDCD11", "PDCD5", "PDCD6IP", "PDE12", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXK", "PEBP1", "PECR", "PELO", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLD2", "POLDIP3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMK", "PPA1", "PPAT", "PPIL1", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKACA", "PRKAG1", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PSPH", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PUDP", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "RAB3GAP2", "RABAC1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RALB", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAVER1", "RB1", "RBL1", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBM7", "RBMX", "RBMXL1", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REEP6", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNH1", "RNPS1", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RTCA", "S100A10", "S100A11", "S100A13", "SAE1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF4", "SCAF8", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SLC12A2", "SLC12A9", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A4", "SLC30A5", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLK", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMN1*", "SMYD3", "SNAP47", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX19", "SNX2", "SOAT1", "SOD2", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAT1", "STAT3", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX5", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT3H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF15", "TAF6L", "TAGLN2", "TAP2", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCP1", "TDRKH", "TEAD1", "TECR", "TES", "TFCP2", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM10B", "TJP1", "TJP2", "TK1", "TKT", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM259", "TMEM38B", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOR1A", "TOR1B", "TP53", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRIO", "TRMT6", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUBGCP5", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UCHL5", "UCK2", "UGCG", "UGGT1", "UNC119", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP19", "USP34", "USP39", "USP47", "USP5", "USP7", "UTP11", "UTP14A", "UTP3", "UTP6", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4B", "VRK1", "VRK2", "VRK3", "WARS", "WASF2", "WDHD1", "WDR1", "WDR33", "WDR4", "WDR74", "WDR82", "WIZ", "WRNIP1", "XAB2", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YEATS4", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZC3H7B", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZNF207", "ZNF281", "ZNF598", "ZNF622", "ZW10", "ZYX", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABHD12", "ACAD11", "ACOX1", "ACOX3", "ACP2", "ACP6", "ADA", "ADAR", "ADPGK", "AFG3L2", "AKT2", "ALG1", "ALG12", "ANO6", "ASAH1", "ASNA1", "ATL2", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP6", "ATP6V0A1", "ATP6V0A2", "AUP1", "B4GALT1", "BCAP31", "CDK1", "CDK4", "CDK5", "CDK6", "CDK9", "CEPT1", "CHST14", "CLCC1", "CLCN3", "CLPTM1", "CLPTM1L", "COMT", "COMTD1", "COPS5", "COPS6", "COX2", "CPOX", "CPT1A", "CPT2", "CTSA", "CTSC", "CYB5B", "CYP51A1", "DERL2", "DHCR24", "DHDDS", "DOCK7", "DOLPP1", "DPAGT1", "ECE1", "ERAP1", "ERAP2", "ERMP1", "EXT2", "FAM177A1", "FDPS", "FECH", "FNTA", "FNTB", "GALNT1", "GALNT4", "GM2A", "GOSR1", "GOSR2", "GPAT4", "GPX8", "HCCS", "HDAC1", "HMBS", "HNRNPK", "IGF2BP2", "IMPAD1", "KDELR1", "KDELR3", "KHSRP", "LAMP1", "LAMP2", "LBR", "LETM1", "LMAN1", "LNPEP", "LPCAT1", "MAGT1", "MBOAT7", "MCL1", "METTL7B", "MFN1", "MFSD3", "MGAT2", "MGST2", "MIA2", "MICU1", "MPC2", "MPST", "MPV17", "MPV17L2", "MSMO1", "MTAP", "MTCH1", "MTCH2", "MTOR", "NAMPT", "NAP1L1", "NAP1L4", "NCEH1", "ND1", "ND5", "NDUFA13", "NDUFB11", "NDUFB9", "NDUFC2", "NNT", "NPEPPS", "NSUN2", "NT5C2", "NT5DC2", "NTMT1", "NUCB1", "NUCB2", "NUP160", "NUP54", "OXA1L", "P3H1", "P3H4", "PAK1", "PANX1", "PARL", "PDK1", "PGRMC1", "PGRMC2", "PIGK", "PITPNA", "PITPNB", "PLD6", "PMPCA", "POLRMT", "PRCP", "PSMD14", "PTDSS2", "PTGES2", "PXMP2", "RABGGTB", "RCN2", "REEP2", "REEP3", "REEP4", "REEP5", "REEP6", "RHBDD2", "SC5D", "SCAMP3", "SCARB1", "SCARB2", "SCO1", "SCO2", "SCPEP1", "SDF4", "SDHB", "SEC11A", "SEC13", "SEC61A1", "SET", "SFXN1", "SFXN2", "SLC12A9", "SLC19A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC2A4", "SLC30A5", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC44A1", "SLC4A7", "SLC6A15", "SLC7A1", "SOAT1", "SPNS1", "SPTLC1", "SQLE", "SSR1", "STT3A", "STT3B", "STX10", "STX18", "STX5", "STX7", "STX8", "SURF4", "SV2A", "SYNGR2", "SYNJ2BP", "SYS1", "TAP2", "TECR", "TIMM10B", "TJP2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TOMM40", "TPBG", "TPP1", "TTYH3", "TUBB2A", "TUBB6", "TYMS", "UGCG", "UNC119", "UQCR10", "USP11", "USP34", "VKORC1L1", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..61535a796704ebaa5615648b4b855d9c5c3c7f08 --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tdark", "1": "Tclin"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..5d1d6c2872d146087cd4ad3c63aa3ea47e713ff6 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5417da1d745955af701adfa1b84f6cfbb635933a81c7a603148ddb347d985412 +size 205453 diff --git a/pharos_protein_category/advanced/plot_1.png b/pharos_protein_category/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..ad0d1aa6dfa6e190756f282e378f4768bb100f42 --- /dev/null +++ b/pharos_protein_category/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:773d2485cd602f41c888109cd1e27fe3636b6976136bcdb2e797eff825196ace +size 189891 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..e483539ad989065e5974df899279b3a56fb561fe --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tdark", "1": "Tclin", "2": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6539ebfc9edc6529ec03b09906ab37258c5203ab --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:06dc1d3eb04baf8401c5b5534a313abdd509d53cf94a4e33724a6817939d6219 +size 137234 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..2774cac806798d35469f8e907637c93d0fd170e6 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a6aba0d2c4f946416ca038a3deafb1254c954ac82ae390d7e5bfd172d28acb86 +size 133468 diff --git a/pharos_protein_category/basic/plot_2.png b/pharos_protein_category/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..119258dd342de3bdd7ac7a229b89c56085ff7364 --- /dev/null +++ b/pharos_protein_category/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ff132cf0d276bd6cfa01afa803b81eac528245aa1d1c60fb2681b7199c5575f +size 125213 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..91473b10dd01cfda2830e09612b3e8dda95b83d8 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1cdb1bf480dbaa17c183065d0e3a6113ef3eeff7db725cdac4919ca2395f0dbc +size 72956 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..817cb812699c0b0de198fda52769f70e15b60f94 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tdark 78 335 3.041246571104788 0.0023560080692599 74.3131067961165 324.373786407767 0.5859664552431031 0.6577158703271868 20.515717939687796 49.369088361677456 1.229854636263473 0.4013924214985833 0.987779985348406 0.9820646970342782 0.9729587365905772 0.7229385926394238 0.9951313471253967 +Tclin 27 91 2.0243871043852266 0.0429303375606913 19.366504854368937 86.39077669902913 0.9399778874953114 0.4805096456956057 6.659845213621253 7.009024167820235 0.9745051203556824 0.3806460486794667 0.00440633877 0.020644202656632 0.1555113717535904 0.0171288069269128 0.0008875698732467 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..78cd44d4967f715010273c0c42e8f065699d19d2 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 799.25 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..23ea2f128e34f1d39342ef5a13de6be32a228011 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c6a53ae2462d89dcf1fc0805a23969225f3f3cf9 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tdark 0.3685406187213982 3.041246571104788 0.0023560080692599 0.0093907799127677 0.0094240322770398 335 Q8N4H5,Q9H1E5,Q9NRY5,Q8N4V1,Q86YN1,Q9H5K3,Q6UW02,Q15629,O75071,O75964,Q5VW38,Q9Y5M8,Q69YU5,Q7Z3D4,O95070,Q9NX62,Q9H4I3,Q96J42,Q9H1A3,Q15005,Q9Y3E0,Q8NBM8,Q9Y3B1,Q9BT17,Q9NPA0,Q9BWH2,Q9H7E9,Q9BRK0,Q96C01,Q9NWZ8,Q8NBN7,Q9HD20,Q8N2H4,Q96ES6,Q9HD45,P84157,Q3SXM5,Q9NRG7,Q8IWB1,Q8N128,Q9H1Z9,Q8WVC6,Q9NPR9,Q8N8L6,Q9Y320,Q8WWC4,Q6UW68,L0R6Q1,Q9P0S9,Q9BVK6,Q8NC54,Q96SK2,Q9Y3B3,Q96IX5,Q9Y2G8,Q5SNT2,Q9NR77,Q69YL0,Q86VU5,Q9BU23,Q96CN7,O43615,Q96NB2,Q6PI78,Q8IXU6,Q9NPL8,Q96GQ5,Q70UQ0,O75935,Q7Z2K6,Q8IYS2,Q9Y6I9,Q5T6V5,Q9GZU8,Q8IZ07,Q86VR2,Q16540,A0AVF1 78 +Tclin 0.3864295876767021 2.0243871043852266 0.0429303375606913 0.1609763550766604 0.0858606751213826 91 P14324,Q99720,O95298,O96000,P49721,Q9Y6M9,O95139,O43676,P03886,Q86Y39,Q7L0J3,Q9P0J0,P28074,Q9Y375,P04818,P38435,P03915,P49841,P23458,P11802,Q16739,P05023,O75306,P21964,O95169,Q9NX14,P04035 27 +Tbio 0.1691388850958646 1.4999894712778696 0.133617129868804 0.4365707000100307 0.133617129868804 2466 O43169,P67812,Q9Y2R0,Q9UM22,Q9NQC3,Q99595,O43657,P43307,O95197,P24390,Q9HCL2,Q96A26,O60637,O60858,Q8WWV3,Q9BRR6,O14949,Q96RQ1,Q567V2,O96005,Q7Z3B4,Q7Z7H8,O75298,Q9H6V9,P50897,Q9BUR5,Q15800,Q8N511,Q5XKP0,Q8N0U8,Q9UHG3,Q9UDX5,O75844,P46977,Q96G23,Q9NS69,Q9Y277,O43396,Q8N8Q8,P21796,P51648,Q86VD7,Q9H4A6,Q92520,Q96A57,Q9Y282,Q9H2D1,P80303,Q9NZ01,O95674,Q9H061,Q9UBX3,Q4ZIN3,O14653,Q8NCH0,Q92543,Q969V5,P13073,Q9UHX1,Q9UG56,P57105,O00461,Q86UE4,Q9P2W9,Q9NZJ7,Q8IXH7,Q15070,Q13505,Q15165,Q8TAD4,Q9C0H2,Q9H2V7,P16615,Q93050,Q9H0B6,P00846,O14773,O14925,P21912,P53701,O15173,Q10713,Q86VX2,Q96JJ7,Q9Y680,P07602,P42167,P36542,Q9H6K4,O00264,Q9H6D7,Q6NTF9,Q8N5M9,Q9Y6C9,Q969Q5,Q9H3H5,Q8NHH9,Q7KZN9,Q9BXS4,Q9NX40,Q6NUK4,Q11206,Q8NF37,O60499,Q9HC21,Q9Y6K0,Q96N66,Q14739,Q06136,Q5H8A4,Q5VV42,Q7LGA3,Q96AA3,P40855,Q7RTS9,P39210,Q9H6H4,Q9Y371,Q96A33,Q9Y241,Q6P4A7,Q9P035,P62072,Q14108,Q53GQ0,Q70HW3,Q9H3K2,P17900,Q9BVG9,Q9H300,Q9NVH1,P30825,Q8N2F6,Q7Z4L5,Q9BXK5,Q9H490,O75845,Q96PC5,Q9NWM8,Q9BT22,Q16799,O75153,Q96S66,Q96KC8,P56378,Q13641,Q9NPH0,Q96PU5,Q8N4Q0,Q14257,P63218,O14828,O15258,O94901,Q32P28,Q96QD8,O14657,Q9Y3A6,Q99735,Q6DKK2,Q8NBJ7,Q96BY9,Q9NR31,P55061,Q8TB61,Q9UBV2,P27544,Q969X5,O95249,Q12981,Q9H3N1,Q9UDW1,Q9Y287,Q9NWW5,Q01105,Q10472,P49902,Q92544,Q9UNS2,P50402,Q8NBM4,Q9Y6N5,Q9Y487,Q92600,O43292,Q15392,Q9BV10,Q07065,Q15067,Q08722,P08670,P40939,Q13423,Q4KMQ2,Q96AG4,Q15041,O75503,Q00765,Q9BSR8,Q9NQX7,Q6UXV4,P51572,Q8IV08,Q96RD7,O14735,P12235,O15118,O75340,P24539,Q8NBX0,Q5T8D3,Q96RT8,Q9BTX1,Q96KA5,Q92791,Q8TCJ2,Q16836,P98194,P11279,O14966,P49755,Q8N0X7,Q9BQT8,Q8N2A8,Q96JX3,Q9BSK2,Q7L5N1,P56385,P62820,Q86XL3,Q9GZP9,O15254,P35613,Q03519,O43681,Q6Y1H2,Q709F0,Q15043,Q96DH6,Q9NVI7,Q6NUK1,Q6UX53,Q92604,Q9Y394,Q9UMX0,Q9NQH7,Q7Z3C6,P61026,P57088,O43808,O75381,O96008,Q8IZ81,Q9H0U3,P48723,P56134,O14681,Q9UBG0,Q9Y6M7,Q86UL3,Q9NQZ5,P51530,Q16880,Q8IXM6,Q8TED1,Q92804,Q9Y221,Q8IWA4,P49257,P16435,O15260,Q96TC7,O43399,O75880,Q96CU9,O60831,Q16637,Q00169,Q969V3,Q8NFH5,Q9NTJ5,P12236,Q8N4A0,Q5T9A4,Q8TBA6,Q9BPX6,Q9BUB7,Q9Y512,Q8TAA9,Q9Y6N1,O95202,P51571,O75648 293 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e5e89907647f74351b84e3fd57d34da864c1714a --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG5", "ALKBH5", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP8", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCCIP", "BCKDHB", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BEND3", "BET1", "BIRC6", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C19orf70", "C1QBP", "C1orf35", "C2CD2", "C2CD5", "C2orf49", "C5orf15", "C8orf33", "C9orf64", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC97", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPI", "CENPK", "CENPU", "CENPV", "CEP170", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG8", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD7", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX18", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHPS", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC19", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FAU", "FBL", "FBXO21", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GIPC1", "GJA1", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH1", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISG20L2", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JAK1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "MACF1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MALT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED14", "MED16", "MED18", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METTL1", "METTL3", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGAT2", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFMT", "MTFP1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MXRA7", "MYBBP1A", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NEMF", "NENF", "NF1", "NFATC2IP", "NFRKB", "NFS1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMK", "PON2", "POP1", "POR", "PPA1", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB29", "RAB2A", "RAB31", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABAC1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP7", "RBFA", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM47", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REEP6", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF2", "RNF25", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARAF", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP3", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDAD1", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A4", "SLC30A5", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP47", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX19", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "ST3GAL4", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STAU1", "STEAP3", "STIM1", "STIM2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TAF15", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TEAD1", "TECR", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX2", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THEM6", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM10B", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM104", "TMEM109", "TMEM126A", "TMEM14C", "TMEM160", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53I11", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRIM13", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIO", "TRIP10", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPAN10", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUBGCP5", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFM1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS13C", "VPS13D", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WBP11", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF131", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZNF830", "ZPR1", "ZRANB2", "ZW10", "ZYG11B", "ZYX", "ZZEF1"], "leading_proteins": ["ACAD11", "ACBD5", "ACOX1", "ACOX3", "ACP6", "ADPGK", "ALDH3A2", "ALG1", "ALG12", "ANKLE2", "ANKRD13A", "ANO6", "APOO", "APOOL", "ARL10", "ARL6IP1", "ARMC10", "ASNA1", "ATAD3A", "ATAD3B", "ATG9A", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2C1", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6", "ATP6V0A1", "ATP6V0A2", "BCAP31", "BCL2L13", "BNIP1", "BSG", "C12orf73", "C14orf2", "C16orf58", "C19orf70", "C5orf15", "C8orf33", "C9orf64", "CCDC47", "CD47", "CDIPT", "CDK4", "CDKAL1", "CDS2", "CEPT1", "CERS1", "CERS2", "CHST14", "CKAP4", "CLCC1", "CLN5", "CLN6", "CLPTM1", "CLPTM1L", "CLUH", "CNOT9", "COA3", "COMMD7", "COMT", "COMTD1", "COPS3", "COPS6", "COX11", "COX15", "COX18", "COX4I1", "CYB5B", "CYP20A1", "DCAKD", "DCTN3", "DERL2", "DHCR24", "DHRS7", "DNA2", "DNAJC1", "DNAJC11", "DNAJC16", "DOLPP1", "DPAGT1", "DYM", "EFCAB14", "EI24", "ELMOD2", "EMC7", "EMD", "EPDR1", "ERGIC1", "ERGIC2", "ERGIC3", "ERMP1", "FAM114A2", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM3C", "FDPS", "FKBP14", "FKBP7", "FOXRED1", "FUNDC2", "GALNT1", "GALNT4", "GEMIN8", "GGCX", "GHITM", "GM2A", "GNG5", "GOLGA5", "GOLIM4", "GOLPH3", "GOLT1B", "GOSR1", "GOSR2", "GPAA1", "GPAM", "GPAT4", "GPR107", "GPR108", "GPX8", "GSK3B", "HACD2", "HACD3", "HADH", "HADHA", "HAUS4", "HCCS", "HIGD1A", "HMGCR", "HS2ST1", "HSD17B12", "HSDL1", "HSPA13", "IKBIP", "IMPAD1", "ISOC1", "ITM2B", "ITM2C", "ITPRIP", "JAGN1", "JAK1", "KDELR1", "KDSR", "KIAA2013", "KLC2", "LAMP1", "LBR", "LDAH", "LETM1", "LMAN1", "LMF2", "LPCAT1", "LPGAT1", "LRRC59", "LYSMD3", "MAGT1", "MAIP1", "MBOAT7", "METTL7B", "METTL9", "MFN1", "MFSD3", "MGST2", "MIA2", "MICU1", "MMGT1", "MPV17", "MPV17L2", "MRC2", "MRPL10", "MRPL23", "MSI2", "MSMO1", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTG1", "MTX1", "MUL1", "MXRA7", "NCBP2AS2", "NCLN", "ND1", "ND5", "NDC1", "NDUFA11", "NDUFA13", "NDUFAF1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS2", "NEDD4L", "NELFCD", "NIP7", "NNT", "NPC1", "NRM", "NT5C2", "NUCB2", "NUP35", "NUP54", "OCIAD1", "OPA3", "OXA1L", "P3H1", "P3H4", "PANX1", "PARL", "PCYOX1", "PCYOX1L", "PDCD6", "PEX14", "PEX19", "PGRMC1", "PGRMC2", "PIGG", "PIGU", "PISD", "PITPNA", "PLD3", "PLD6", "PMPCA", "POMK", "PON2", "POR", "PPT1", "PRAF2", "PRELID3B", "PSAP", "PSMB2", "PSMB5", "PTDSS2", "PUF60", "PXMP2", "RAB10", "RAB1A", "RAB24", "RAB29", "RCN2", "RDH13", "REEP2", "REEP3", "REEP4", "REEP5", "RER1", "RETREG3", "RFT1", "RHBDD2", "RMDN3", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "SACM1L", "SAMM50", "SAR1A", "SARAF", "SC5D", "SCAMP3", "SCARB2", "SCCPDH", "SCO1", "SDHB", "SDR39U1", "SEC11A", "SEL1L", "SERAC1", "SET", "SFXN2", "SFXN4", "SH3GLB1", "SIGMAR1", "SLC25A10", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A6", "SLC30A5", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC4A7", "SLC7A1", "SMN1*", "SNX19", "SPART", "SPCS2", "SPNS1", "SQOR", "SRPRB", "SSR1", "SSR4", "ST3GAL4", "STARD7", "STT3A", "STT3B", "STX10", "STX18", "SUMF2", "SUN1", "SURF4", "SV2A", "SYNJ2BP", "SYS1", "TAF15", "TAP2", "TECR", "TEX264", "TIMM10", "TIMM17A", "TIMM23", "TIMM44", "TIMMDC1", "TM9SF3", "TM9SF4", "TMBIM6", "TMED10", "TMED5", "TMED7", "TMED9", "TMEM126A", "TMEM14C", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM230", "TMEM259", "TMEM33", 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https://git-lfs.github.com/spec/v1 +oid sha256:6ed8ef36f8567dba06f4ee747f7105237291d37eda2afed02d66bcabb11984f4 +size 105837 diff --git a/protein_atlas_biological_process/df_merge.tsv b/protein_atlas_biological_process/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..080032a67a343ab0b9bd67a5c9c2f30c05fabf15 --- /dev/null +++ b/protein_atlas_biological_process/df_merge.tsv @@ -0,0 +1,25 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transport 213 505 5.674505294754067 1.3909001536603913e-08 127.39320388349516 491.7621359223301 1.4832290368286314 0.5289485259644714 40.31460927260851 50.077723312236 2.248556521823017 0.4543981544818752 6.263830455450541e-25 2.194428129599496e-05 1.5616195469401417e-11 3.2153156475635167e-16 2.4101559600441217e-27 +Ion transport 34 65 4.105868482086077 4.027986214549806e-05 19.82766990291262 54.68446601941748 1.177785596906995 0.303722365376275 8.99659651977233 7.41832233515522 1.8666057057567336 0.3607289685223158 2.922944786404489e-07 0.6069167841052098 0.0023186425208291 0.0007601057405152 2.4703678964537503e-09 +Electron transport 17 50 3.70026466528798 0.0002153747278292 14.983009708737864 45.592233009708735 1.1180311721330871 0.3315827540150002 5.69510117113123 4.184313965655804 1.5984402393879058 0.3574888993156041 5.034432316806525e-10 3.512991171897707e-07 3.614184244541911e-06 1.126146951633262e-09 4.826839407312441e-09 +Lipid metabolism 60 138 3.467275919156716 0.000525761900791 32.65533980582524 126.3009708737864 0.0122638234126047 0.3570579745388888 13.120525890444084 12.789813112229345 1.8284441878622113 0.3670562446523409 4.409960987719364e-18 0.0150772225050493 0.0024254885593627 2.1984488238709835e-10 1.3915431505037777e-18 +Phospholipid metabolism 11 20 3.24036221651515 0.0011937794961884 5.706310679611651 15.194174757281552 0.9499140430417652 0.282763149469861 3.1039684871946744 2.8053632837701987 1.3505948321648105 0.2868829019946007 1.2870195109304598e-07 0.2030241760545403 0.0100008174701386 1.4280312346792963e-05 1.5517180598116607e-06 +Phospholipid biosynthesis 10 19 3.132316065483677 0.0017343305981585 5.393203883495145 14.228155339805824 0.6697741038582752 0.3412824299901092 3.008201157028892 2.7679482245749822 1.3258103202069491 0.2976917551215703 3.273242177454012e-07 0.1835089509173778 0.0073262411490521 5.730965752523082e-05 3.237914192639061e-06 +Respiratory chain 14 37 3.12521878005748 0.001776728630612 10.895631067961164 31.91990291262136 1.1075564231308468 0.3095707256998049 4.44287149555612 3.6670789399383112 1.4970961025113558 0.3356221172021658 5.927947805226977e-09 1.0107094207806202e-05 0.000274261654928 1.8190494996864507e-08 1.835329110209276e-08 +Sphingolipid metabolism 9 11 2.9990226201262744 0.0027084719740373 5.075242718446602 9.720873786407768 1.0723891387155546 0.1672146303539832 2.245095774833478 1.0461446620678432 1.744521381224598 0.248179764200939 1.0517486258725468e-08 1.0 0.1662183776826317 1.7195968795888636e-07 3.901185689413069e-09 +Protein transport 77 245 2.879320526705243 0.0039853306046655 60.970873786407765 250.03155339805824 0.5647835050770387 0.6753991045983436 18.49610628700502 28.95320084782557 1.0712917387948182 0.3856428267622117 7.465817343214144e-05 0.1255103805351744 0.0158511507018085 0.001862388275911 2.5149272547938224e-05 +ER-Golgi transport 22 53 2.8615959126639647 0.0042151394350049 13.189320388349516 50.09466019417476 1.0113245710455496 0.4417664900586612 5.844513029144237 4.526971021787617 1.2802141654412966 0.393016134031976 2.001673291731728e-06 0.0068431745235502 0.0010170845131467 2.324281999158176e-05 6.1938185658196045e-06 +Lipid biosynthesis 31 59 2.848415309585236 0.0043937545785064 15.9126213592233 54.70145631067961 0.536392080403718 0.3712014565741516 7.84820404428356 6.53895703030749 1.480689631873909 0.3519149032884112 8.581183665236536e-14 0.0210980544122528 0.0011017373238203 5.586046242564919e-09 3.460297540678096e-12 +Calcium transport 9 12 2.6159905963210464 0.0088969007810142 3.7305825242718447 8.240291262135923 0.5020754788348019 0.3462849026834517 2.2148520410126937 1.861210565609195 1.3394131933179945 0.3209721672484884 0.0515741689374079 1.0 0.2983459236646945 0.224257489169728 0.0017012881386174 +Translocation 13 49 2.5695173499415023 0.010184029204288 12.434466019417476 47.86165048543689 1.1297087783550883 0.3515144245437065 6.687771513864753 3.601211391947168 1.550426642680832 0.3811939235350816 0.0019564139175552 0.0053226708337122 0.005326863777972 0.0087565646797269 9.740232609652992e-06 +Antiport 6 8 2.4890379569644705 0.0128089289798163 3.2063106796116503 7.097087378640777 0.8539962634551548 0.3166005193161004 2.0440914093762896 1.1428508308135348 1.2051823486844502 0.2998011899649158 0.176883840010458 1.0 1.0 1.0 2.6131601312709008e-05 +Sterol metabolism 13 26 2.4696841663245577 0.0135232388917461 7.606796116504855 25.203883495145632 1.1785484151208083 0.2872927387372206 3.1377365577760563 3.096691699470945 1.2399567569518877 0.3064799172119154 7.123909799495808e-05 0.2068720246529641 0.3686542667111886 0.0057706709278987 1.9796041881201847e-06 +Amino-acid transport 5 8 2.4651954743263467 0.0136938522458747 3.063106796116505 7.016990291262136 0.9299828460487652 0.271909550896337 1.9171930478617292 1.3907470472448622 1.1684874391815692 0.271335812648974 0.0044374904949104 1.0 1.0 0.0319451393300601 0.0116464914628391 +Steroid metabolism 13 27 2.406359238740011 0.0161124119214324 7.703883495145631 26.439320388349515 1.128083592407629 0.3052190273048834 3.279782799169419 3.1412859163137186 1.216134343451914 0.3162944576553002 0.0002131959016045 0.2333020504203794 0.4097170027262437 0.0102355224712358 9.155118175115372e-06 +Steroid biosynthesis 11 20 2.328334422574532 0.0198943528286432 6.351941747572815 21.094660194174757 1.1936032046421512 0.306057763510231 2.838692628881621 2.6297902443336034 1.071011617665077 0.2981933340003868 1.1902565955943655e-05 0.134742527043449 0.2496255286594674 0.0006827439557333 7.599264280056233e-06 +Cholesterol metabolism 11 24 2.2092865631317884 0.0271547152017186 7.111650485436893 23.79854368932039 1.169709264926864 0.2871268807807383 2.8890755390042298 2.7173834172675666 1.205315163774447 0.3061468445376054 0.0002651484140493 0.1952735388158895 0.3502020618548794 0.0227330174276438 6.731095454305301e-06 +Sterol biosynthesis 9 15 2.185621681997369 0.0288432949940422 4.970873786407767 15.854368932038836 1.2489526119817105 0.2730082640054638 2.2746228138386324 2.237837752303934 0.9571049414552286 0.2704007779320353 1.1762953804642804e-05 0.1006582454154426 0.1898352204968973 0.0017174581383874 4.874999040450038e-06 +Hydrogen ion transport 7 20 2.054939328582963 0.0398848651902492 6.152912621359223 19.560679611650485 0.8019462838912398 0.3170771992837126 2.890966221074556 1.405159537040464 1.2709247974732976 0.29451915785821 1.551226931248594e-05 1.0 0.2567853086841904 0.0062346640440273 8.185660717991886e-05 +Sodium transport 3 7 2.0337458755950824 0.0419772241576315 2.6432038834951457 6.033980582524272 0.3870777500167291 0.4312394754850888 1.6104565556558244 1.45275455788244 1.082646403381691 0.3149069735017896 0.1306895040375719 1.0 1.0 0.5539124029112868 0.0726348754294577 +Apoptosis 28 121 2.0141965592253377 0.0439889008041058 26.983009708737864 120.21844660194176 0.6636399997719048 0.5877814963058052 7.904294191754799 11.993762517847651 0.9312427807662368 0.388650277956022 0.0233879288579721 0.0973993414784368 0.0227290606479154 0.0310861731931 0.0299927268236454 +ATP synthesis 4 9 1.966148169580637 0.0492814975423767 2.6092233009708736 7.560679611650485 0.4760838469956283 0.2927439020529209 1.766795238887657 0.7130595396318904 1.333549443047025 0.2645430394314645 5.060037785875628e-05 1.0 0.1084298440104649 0.0025975272437437 0.0001530581700288 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9bce2c51307458c4f3ed42aada2a80c4d2a14f37 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 168, + "title": "Average number of proteins per term", + "value": 31.05952380952381 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a51dd3955df978b429d2ea908dd5d1c449cb464e --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3e5f406ecc91ba00d7065ddf83d75436d137eceb --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,52 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport 0.4899144156254533 5.674505294754067 1.3909001536603911e-08 2.3367095444581236e-06 2.336712258317457e-06 505 O43169,O75431,Q99595,Q8TBP6,O95197,P24390,O96000,Q9BVC6,Q15904,O14949,P45880,Q8N4H5,Q96RQ1,Q9UNK0,O43676,O95139,Q6IQ22,Q7Z3B4,P03886,Q86Y39,Q13190,P61019,Q9H1E5,O75352,P46379,Q9BUR5,Q8WWI5,Q8N4V1,Q9NS69,Q9Y277,O43396,Q3ZCQ8,P21796,Q86VD7,Q9H4A6,Q9Y282,Q9H2D1,P20020,Q9H936,Q9UBX3,Q15629,P23634,O75964,O14653,Q92543,O75027,O00461,Q9P2W9,Q9NZJ7,Q9Y3C0,Q13505,Q9H9B4,Q8TAD4,Q9C0H2,Q9H2V7,P16615,O95563,Q93050,Q9HD26,Q9Y5J6,P00846,Q96HE7,O14925,P21912,O43731,Q9Y6M1,O95070,O95169,P36542,Q92945,Q5JRA6,P51970,Q8N5M9,Q9Y6C9,Q9Y3E0,Q969Q5,Q9BZF1,Q13586,Q99720,O95298,Q9Y6M9,O60499,Q07955,Q9HC21,Q96JB2,Q96AA3,Q16134,Q9HD23,P00403,Q9BXB4,Q9HD20,Q8N2H4,Q96ES6,Q9Y241,Q6P4A7,Q9P0J0,Q02978,P62072,Q8TDW0,Q70HW3,Q8TEX9,P22626,P30825,O15027,O00483,P28288,Q9Y5U9,Q96S66,P41208,P03915,O75396,Q9Y6B6,Q9BXP2,O14828,Q86Y82,Q96QD8,Q9Y3A6,O14964,Q6DKK2,Q96BY9,Q9NR31,Q9UJS0,Q8TB61,Q13432,Q14728,Q9HCU5,Q969X5,O95249,Q96DA6,Q12981,Q96D46,Q9H3N1,Q9UDW1,O95864,Q15388,O75746,Q92973,Q9BRG1,Q9Y5J9,Q00325,Q9Y5L0,Q9Y487,Q96RL7,P14672,P53007,Q9BVK6,Q9Y3B3,Q4KMQ2,Q7L0J3,P41440,P08183,P51572,Q96RD7,P12235,O15118,P24539,Q5T8D3,Q9BTX1,P98194,O14966,P49755,Q9BQT8,Q9H2J7,Q9BSK2,P56385,P62820,Q03519,O43681,Q15043,P23786,Q6NUK1,Q7Z3C6,P61026,O43808,O75381,O96008,Q9H0U3,P56134,Q9Y6M7,O43615,Q9NX14,P49257,Q96CU9,O60831,Q96NB2,Q00169,Q8NFH5,P12236,Q9BPX6,O95202,Q8IXU6,P48739,P51790,Q9UM00,O14678,O15504,Q9H0U4,Q99442,Q12769,P51798,P61619,Q658P3,Q15363,A0AVF1,Q9H1P3,O43823,P31751,Q9UGP8,P05141,P05023,O75306,P50416,O15498 213 +Ion transport 0.6252851213592658 4.105868482086077 4.027986214549806e-05 0.0067443075129189 0.0033835084202219 65 Q9BVC6,Q9Y487,Q15904,Q9BPX6,P45880,O95202,Q4KMQ2,P51790,Q96RD7,Q9Y277,P24539,P21796,Q9UM00,P20020,P98194,Q9H2J7,P51798,O75964,Q658P3,P56385,Q96S66,Q15043,Q8TAD4,Q9C0H2,Q96QD8,P16615,Q93050,P00846,O96008,Q96BY9,P56134,P05023,Q9Y6M7,P36542 34 +Electron transport 0.6056590146320648 3.70026466528798 0.0002153747278292 0.0355399339538401 0.0107278463775686 50 O43169,Q6DKK2,P00403,O95298,P21912,O96000,Q9Y241,Q9Y6M9,Q9P0J0,O14949,O43396,P03915,O43676,Q9H3N1,P03886,Q86Y39,Q9H1E5 17 +Lipid metabolism 0.4546073440821535 3.467275919156716 0.000525761900791 0.0845607069487614 0.0147213332221483 138 P14324,O00767,Q9HCL2,Q15392,Q9UHQ9,Q11206,Q8NF37,Q15067,Q9H7Z7,Q8NCG7,Q9Y6K0,Q96N66,P40939,Q14739,Q06136,Q8N2K0,O95470,Q6PIU2,Q9H6V9,Q15800,P35610,O14735,Q16850,Q96G23,O15118,Q9P035,O15269,P51648,Q53GQ0,P17900,Q9BVG9,Q16836,Q9NZ01,O95674,Q8N2A8,Q96JX3,O75845,O15254,Q9UG56,Q9NPH0,Q6Y1H2,Q709F0,P23786,P37268,Q92604,Q12770,Q99735,Q9UBM7,P04062,Q16739,P50416,P27544,Q86UL3,P07602,A1L0T0,Q16880,Q13510,Q8NBQ5,P04035,P09960 60 +Phospholipid metabolism 0.7436207034834056 3.24036221651515 0.0011937794961884 0.1818215072710073 0.0198134384804311 20 Q96JX3,Q9HCL2,O14735,Q9UG56,Q8NF37,Q9NPH0,Q9Y6K0,Q96N66,Q9BVG9,Q92604,O95674 11 +Phospholipid biosynthesis 0.7334256357822878 3.132316065483677 0.0017343305981585 0.2529480092148548 0.0220499190142455 19 Q96JX3,Q9HCL2,O14735,Q9UG56,Q8NF37,Q9Y6K0,Q96N66,Q9BVG9,Q92604,O95674 10 +Respiratory chain 0.5844227074972421 3.12521878005748 0.001776728630612 0.2582595483879346 0.0220499190142455 37 Q6DKK2,P00403,O95298,O96000,Q9Y241,Q9Y6M9,Q9P0J0,O14949,P03915,O43676,Q9UDW1,Q9NX14,P03886,Q86Y39 14 +Sphingolipid metabolism 0.8646300954752832 2.9990226201262744 0.0027084719740373 0.3659583390817249 0.028438955727392 11 P04062,Q16739,P07602,Q16880,Q9NZ01,Q13510,P17900,Q06136,O95470 9 +Protein transport 0.382910621843416 2.879320526705243 0.0039853306046655 0.4887380803450162 0.036907538459454 245 O75431,Q99595,P24390,Q8N4H5,Q6IQ22,Q7Z3B4,P61019,Q3ZCQ8,Q9NS69,Q9H4A6,Q15629,O14653,Q92543,Q9P2W9,Q9Y3C0,Q13505,Q9HD26,Q9Y5J6,O43731,O14925,O95070,Q5JRA6,Q8N5M9,Q9Y3E0,Q969Q5,O60499,Q96JB2,Q9HD20,Q8N2H4,P62072,Q8TEX9,O15027,Q9Y5U9,P41208,O75396,Q9Y6B6,O14828,Q86Y82,Q9Y3A6,O14964,Q9NR31,Q13432,Q9HCU5,O95249,Q96DA6,Q96D46,Q15388,Q92973,Q9BRG1,Q9Y5J9,Q9Y5L0,Q9BVK6,Q9Y3B3,P51572,Q9BTX1,O14966,P49755,P62820,Q03519,Q7Z3C6,P61026,O75381,O96008,O43615,P49257,O60831,Q8NFH5,O15504,Q9H0U4,Q99442,Q12769,P61619,Q15363,A0AVF1,O43823,Q9UGP8,O15498 77 +ER-Golgi transport 0.5117730083591363 2.8615959126639647 0.0042151394350049 0.5081788249862337 0.036907538459454 53 O95197,P24390,Q96RQ1,P61019,P51572,Q9Y282,O15027,P49755,P62820,O75396,Q15363,Q9Y6B6,Q9P2W9,O43731,Q9NR31,O95070,Q969X5,O95249,Q12981,Q5JRA6,P49257,O15498 22 +Lipid biosynthesis 0.5042294071358695 2.848415309585236 0.0043937545785064 0.5227797533198826 0.036907538459454 59 P14324,O00767,Q9HCL2,Q15392,Q9UHQ9,Q8NF37,Q9H7Z7,Q9Y6K0,Q96N66,Q14739,Q15800,O14735,Q16850,Q96G23,Q9P035,Q53GQ0,Q9BVG9,Q9NZ01,O95674,Q96JX3,O75845,Q9UG56,Q6Y1H2,P37268,Q92604,Q9UBM7,Q16739,P27544,Q86UL3,Q8NBQ5,P04035 31 +Calcium transport 0.7661897275349303 2.6159905963210464 0.0088969007810142 0.7771748821641702 0.0528371976597311 12 P23634,Q96BY9,Q96RD7,Q9BPX6,O95202,Q9UM00,P20020,P98194,P16615 9 +Translocation 0.4849967434601939 2.5695173499415023 0.010184029204288 0.8208780687048021 0.0534661533225123 49 Q99442,Q15629,Q12769,Q99595,O75381,Q8NFH5,O14925,Q9NS69,O43615,P62072,Q9BTX1,Q7Z3B4,O15504 13 +Antiport 0.811428787840204 2.4890379569644705 0.0128089289798163 0.8853419048795466 0.063904643814082 8 P41440,P51798,P51790,P12236,P12235,O95202 6 +Sterol metabolism 0.5811184627494097 2.4696841663245577 0.0135232388917461 0.8984704915158391 0.063904643814082 26 P14324,Q15800,Q12770,Q9UBM7,O75845,P04062,P35610,P37268,Q15392,Q16850,O15118,P04035,Q14739 13 +Amino-acid transport 0.8063823529135136 2.4651954743263467 0.0136938522458747 0.9013783321144092 0.063904643814082 8 Q96NB2,Q9H2J7,Q6P4A7,P30825,Q96QD8 5 +Steroid metabolism 0.5653694342809515 2.406359238740011 0.0161124119214324 0.9347108582999608 0.0731590595351526 27 P14324,Q15800,Q12770,Q9UBM7,O75845,P04062,P35610,P37268,Q15392,Q16850,O15118,P04035,Q14739 13 +Steroid biosynthesis 0.5998670937242659 2.328334422574532 0.0198943528286432 0.9658141978123772 0.0879539809266334 20 P14324,Q15800,Q9UBM7,O75845,P37268,Q15392,Q16850,Q53GQ0,Q8NBQ5,P04035,Q14739 11 +Cholesterol metabolism 0.5586658711499363 2.2092865631317884 0.0271547152017186 0.9901970959142986 0.10609284078811 24 Q15800,Q12770,Q9UBM7,P04062,P35610,P37268,Q15392,Q16850,O15118,P04035,Q14739 11 +Sterol biosynthesis 0.6294331978399984 2.1856216819973695 0.0288432949940422 0.9926784240029344 0.1076816346444244 15 P14324,Q15800,Q9UBM7,O75845,Q14739,Q15392,Q16850,P04035,P37268 9 +Hydrogen ion transport 0.5597554779477851 2.054939328582963 0.0398848651902492 0.9989276981675376 0.1340131470392375 20 Q93050,P00846,O75964,P56385,Q9Y487,P24539,P36542 7 +Leukotriene biosynthesis 0.9205256570713392 2.0420397253065015 0.0411475909606522 0.9991404002028156 0.1355450055174426 2 Q99735 1 +Sodium transport 0.7686322180200623 2.0337458755950824 0.0419772241576315 0.9992567411016416 0.1356187242015787 7 Q9H2J7,Q9Y6M7,Q96QD8 3 +Apoptosis 0.3629731346197364 2.0141965592253377 0.0439889008041058 0.9994778768098028 0.1394365157564111 121 Q07820,O95197,P12236,Q96A26,Q15041,O95470,P46379,P09601,Q9Y371,Q9UDX5,P51572,O60313,Q9P0J0,O75340,P21796,Q9H3K2,Q96KA5,Q9BXK5,Q658P3,Q969V5,Q9UHX1,Q9NZJ7,P31751,P55061,O14681,Q12981,Q96TC7,Q9NR28 28 +ATP synthesis 0.6903772024651427 1.966148169580637 0.0492814975423767 0.999794540165384 0.1485014297345677 9 P56385,P36542,P00846,O75964 4 +Neurotransmitter transport 0.8986232790988735 1.9455622243221553 0.0517073484023189 0.999866241708972 0.1500599806698221 2 Q7L0J3 1 +Symport 0.7463044981569769 1.9286364569240064 0.0537760098031818 0.9999073203459294 0.1500599806698221 7 Q9H936,Q9H2J7,Q9Y6M7,Q96QD8 4 +Zinc transport 0.8939299123904989 1.9248053636735032 0.0542537127353097 0.9999148586821016 0.1500599806698221 2 Q8TAD4 1 +Cholesterol biosynthesis 0.6008913435008464 1.802857430033016 0.071410608061007 0.9999960700716568 0.1845689562192183 13 Q15800,Q9UBM7,Q14739,Q15392,Q16850,P04035,P37268 7 +GPI-anchor biosynthesis 0.7571774663465438 1.7481710233905154 0.0804344175559979 0.999999238105285 0.2016863007374275 6 Q5H8A4,O43292,Q9H490 3 +Unfolded protein response 0.6114422898520391 1.6162680228682054 0.106036377344191 0.9999999933666296 0.2440289232030697 10 P55061,Q15629,Q9GZP9 3 +Ubiquinone biosynthesis 0.8185231539424265 1.5879767584253168 0.1122915947421359 0.9999999979610068 0.2549322691443085 2 Q8NI60 1 +Autophagy 0.401614645532374 1.4723626555199032 0.1409229720368865 0.9999999999917322 0.3074683026259343 37 Q7Z3C6,Q969Q5,Q9Y371,Q9BXS4,P62820,P55061,O14681,Q5T8D3,Q6IQ22,Q9Y6I9,Q8IXJ6,Q9UMX0,Q9H0U4 13 +Spermatogenesis 0.4470431760750873 1.3573495863137108 0.1746701586407628 0.99999999999999 0.3535492367668453 24 Q8N2A8,Q08J23,Q9Y2W6,O94901,Q16181,P46379 6 +Potassium transport 0.6563324289115657 1.2828560356006145 0.1995425179953456 1.0 0.3809448070820234 6 Q9NUT2,P05023 2 +Peroxisome biogenesis 0.7696400625977923 1.0830176546800212 0.2788005868290999 1.0 0.470265683769214 3 P40855,P56589 2 +Lipid transport 0.4126986055711888 1.0820844255320217 0.2792150155726951 1.0 0.470265683769214 24 Q9BUR5,Q4KMQ2,Q9H2V7,Q99720 4 +Sensory transduction 0.5649960011086056 1.0388281866361604 0.2988846498780795 1.0 0.4812145976176695 7 P50897,Q13432,Q9H6K4 3 +Vision 0.5649960011086056 1.0388281866361604 0.2988846498780795 1.0 0.4812145976176695 7 P50897,Q13432,Q9H6K4 3 +Sugar transport 0.7561815336463025 1.0291435009938388 0.3034122471399929 1.0 0.4812145976176695 3 Q96AA3,P31751 2 +DNA synthesis 0.6911764705882288 1.0160460497742103 0.3096074582038732 1.0 0.4816116016504694 2 P04183 1 +Heme biosynthesis 0.5121355370808794 0.7755823909970107 0.4379956008252401 1.0 0.6183467305768096 7 Q9P0S9,P22830 2 +Sodium/potassium transport 0.6748671116452709 0.7120410287959736 0.4764393697458577 1.0 0.6454985009460008 3 P05023 1 +Osteogenesis 0.5610137672089998 0.4792667895474516 0.6317488450727688 1.0 0.7690855505233708 2 Q9NR12 1 +Hypusine biosynthesis 0.5456821026282812 0.4244131426437086 0.6712645375411825 1.0 0.7998045553682175 2 P49366 1 +Adaptive immunity 0.3383647726517987 0.2574310194954506 0.796846059474499 1.0 0.9203168789532876 14 Q6P179,Q03519,Q9NZ08,P10321,P04439 5 +Glycogen biosynthesis 0.4651106751193466 0.2536069945172695 0.7997991924236905 1.0 0.9203168789532876 4 P31751 1 +Phagocytosis 0.5223787167449226 0.2178879158067098 0.8275164427471031 1.0 0.9426516070960732 3 P50570,P20339 2 +GMP biosynthesis 0.5092331768388189 0.1861122514562649 0.8523567344940157 1.0 0.9546395426332976 3 P20839,P12268 2 +Porphyrin biosynthesis 0.4115232836178227 0.1425529682237259 0.88664324392671 1.0 0.9864640064879951 5 P22830 1 +RNA-mediated gene silencing 0.3065259372206291 0.1212410173927584 0.903500136545514 1.0 0.9913614852637253 15 Q9NZN8,Q92600,O75569,Q9Y2W6 4 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cbfd330ba3be267fd1d1af9fe6a50fbe3bec19c3 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Complement pathway", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Iron transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sexual differentiation", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF3", "ABHD12", "ABHD16A", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN4", "ACTR3", "ADA", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMFR", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "API5", "APOO", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFIP2", "ARG2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL8B", "ARMC10", "ARMT1", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP8", "AUP1", "AURKA", "BABAM1", "BABAM2", "BAG3", "BAG6", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BEND3", "BET1", "BIRC6", "BMS1", "BNIP1", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C2CD5", "CACYBP", "CAD", "CALCOCO1", "CAMK1", "CAMK2G", "CAND1", "CANX", "CAPRIN1", "CARM1", "CARS", "CASP2", "CBL", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC86", "CCNB1", "CCNB2", "CCNK", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPU", "CENPV", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT9", "COASY", "COG3", "COG8", "COL4A3BP", "COMMD1", "COMMD7", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPZ1", "COQ8A", "COQ9", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CROT", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC15", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DEGS1", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHPS", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJB4", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPYSL2", "DSG2", "DST", "DTYMK", "DUS2", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFL1", "EFTUD2", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC10", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM162A", "FAM208A", "FAM50A", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO21", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXC1", "FOXRED1", "FRYL", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCC2", "GCLC", "GCN1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GHITM", "GINS3", "GINS4", "GLE1", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRIPAP1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HINT2", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPF1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPB11", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INA", "INCENP", "ING5", "INTS13", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "ISG20L2", "IST1", "ISY1", "ISYNA1", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF1B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRR1", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDAH", "LDLR", "LDLRAP1", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC41", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "MACF1", "MAGT1", "MALT1", "MANF", "MAP3K7", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARCH5", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MECP2", "MED14", "MED16", "MED18", "MED21", "MED23", "MED24", "MED4", "MESD", "METTL1", "METTL3", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MKRN2", "MLEC", "MMGT1", "MMS19", "MOCS3", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MRC2", "MRE11", "MRI1", "MRPL58", "MRPS27", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTFMT", "MTFP1", "MTG1", "MTHFD1L", "MTHFD2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUL1", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCEH1", "NCKAP1", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NFRKB", "NFS1", "NHP2", "NIP7", "NIPBL", "NKRF", "NLE1", "NMD3", "NME1", "NME2", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NPC1", "NPLOC4", "NPM1", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NUBP1", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC2", "ORC3", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTULIN", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PANX1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCF11", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDK1", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PECR", "PELO", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PMVK", "PNN", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "PPAT", "PPCDC", "PPHLN1", "PPID", "PPIF", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R8", "PPP2R1A", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRELID1", "PRIM1", "PRIM2", "PRKAG1", "PRKCA", "PRKCD", "PRKDC", "PRKRA", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPMT1", "PTRH2", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PVR", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB29", "RAB2A", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP2", "RANBP3", "RANBP6", "RARS", "RARS2", "RB1", "RBBP5", "RBBP7", "RBFA", "RBL1", "RBM10", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHOA", "RIF1", "RINT1", "RIPK1", "RMDN3", "RMND1", "RNF2", "RNF25", "RNF40", "RNMT", "RNPS1", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPP38", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RTCB", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARAF", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP3", "SCAP", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDE2", "SDF4", "SDHA", "SDHB", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SENP3", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERPINH1", "SET", "SETD2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A4", "SLC30A5", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX19", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SON", "SORT1", "SPATA5", "SPC24", "SPC25", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SREK1", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "ST3GAL4", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STAU1", "STEAP3", "STIM1", "STIM2", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT3H", 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setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Primary mitochondrial disease 33 103 3.777448320339957 0.0001584433688857 27.53640776699029 92.44660194174756 0.9978626953080288 0.3665723479658412 11.863754653333944 10.66022291187525 1.7959996823414457 0.3879563837717744 4.191787865289884e-09 0.0001377367296412 0.0001836390015348 1.033055855893856e-07 2.653730039403519e-12 +Congenital disorder of glycosylation 13 23 3.052576838350729 0.0022688563561623 5.618932038834951 18.325242718446603 0.4013656328493284 0.4500757016048167 2.8520016519219875 3.440343696044481 1.1296344785223882 0.3186521023843959 0.0002651484140493 0.0196403757049561 0.0681167311872175 0.0043649502990921 9.32963770322802e-07 +Neurodegeneration 39 140 2.9114541386003725 0.0035975071497302 27.95631067961165 134.69660194174756 0.269943056894121 0.615157984625689 9.104465669482156 13.994023970959963 0.954862652984542 0.3632698211987682 2.771129446518656e-05 0.1718626745247942 0.1541540298936985 0.0023290155848125 6.680864293806899e-06 +Hereditary spastic paraplegia 5 16 2.6019531470166832 0.0092694515034308 4.0 14.555825242718448 0.0919664485976789 0.5930985184955906 2.2186324835554396 2.9203487703241335 0.8060709217258477 0.2853810183745407 0.0138898587919726 0.2220822570468345 0.3924527927004838 0.1300529274831162 0.0381119455430847 +Ichthyosis 1 7 2.1725235028739496 0.0298161988463447 2.424757281553398 8.70873786407767 0.6701903086786922 0.3798909770564678 1.5631275250389387 1.4270688811262522 1.102920967881483 0.3152318826682235 0.2621127843418628 1.0 0.2202973788945578 0.1292409073430241 0.3593308196629 +Cataract 13 27 2.037509654053759 0.0415989954930282 7.509708737864078 26.679611650485437 0.6066406061606927 0.4718259290301406 3.570701015264242 3.2395121058789256 1.0572468917106954 0.3422408621391183 0.0660498191675765 0.2406936845278361 0.1021730546658088 0.1582640101113092 0.0557014909025289 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a3e683c9e590f89bcdce09761671a9848aec65a2 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 119, + "title": "Average number of proteins per term", + "value": 21.915966386554622 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..dc872d84722673fdcaf717aabe482b561843f5e5 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ee8f36f49a5653b94cf34e077bca07717abb6f81 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,45 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Primary mitochondrial disease 0.4946742269213563 3.777448320339958 0.0001584433688857 0.018679587757989 0.0188547608973993 103 Q96CU9,Q9Y2R0,Q7KZN9,Q9Y6M9,Q9BUB7,O14949,O43676,P03886,Q86Y39,Q96IX5,Q9NPL8,Q5XKP0,P39210,P00403,O60313,Q6P4A7,Q9P0J0,P12235,Q70HW3,Q9UBX3,Q9BQT8,Q9Y375,P13073,P03915,Q8NI60,Q9NWS8,P00846,Q6DKK2,O75306,O43819,P51530,Q9NX14,O75880 33 +Congenital disorder of glycosylation 0.6881055443311973 3.052576838350729 0.0022688563561623 0.2368499881946583 0.0555453284438397 23 Q96AA3,Q9H3H5,Q8N511,Q9H0U3,Q9BT22,Q15904,Q10469,Q9BV10,P46977,P15291,P51571,Q2TAA5,Q8TCJ2 13 +Neurodegeneration 0.4150690545138845 2.9114541386003725 0.0035975071497302 0.3487588368682227 0.0555453284438397 140 P49902,Q16637,Q99720,P07196,O15020,Q9BRK0,P03886,O75298,Q15041,P50897,O75503,Q8WWI5,P39210,Q8IV08,O60313,O15269,Q8TB36,Q14108,Q96A57,Q9Y4W6,Q9NSD9,Q8N0X7,O14653,Q9UBB4,Q8NI60,Q15043,Q8IXJ6,P61026,Q9H0B6,O14773,P04062,Q10713,P05023,P27544,Q9Y320,P35637,Q13510,Q9Y287,Q9NWW5 39 +Hereditary spastic paraplegia 0.677717126861984 2.6019531470166832 0.0092694515034308 0.6698502519462326 0.0919220607423558 16 P49902,Q9H0B6,Q9BRK0,Q15041,O75298 5 +Gaucher disease 0.964956195244055 2.2356348010517655 0.0253757030323056 0.9530505141299545 0.1982789034877339 2 P04062 1 +Ichthyosis 0.798507538456656 2.1725235028739496 0.0298161988463447 0.9727335705899895 0.1982789034877339 7 P51648 1 +MELAS syndrome 0.9352315394242884 2.10644127498326 0.0351660391593067 0.985879267853594 0.1982789034877339 2 P03886 1 +Neuronal ceroid lipofuscinosis 0.910457107075761 2.056839600768291 0.0397016574323987 0.9919399945460744 0.1982789034877339 4 P50897,Q9NWW5,O14773 3 +Cataract 0.5174112336577408 2.037509654053759 0.0415989954930282 0.993630226823226 0.1982789034877339 27 Q15800,P48449,Q53H12,Q9UG56,P17302,Q8TC12,Q8NC56,O15228,P08670,Q8N2K0,Q9H6K4,Q8WVX9,O76024 13 +Ehlers-Danlos syndrome 0.8444035399721657 1.7843702645533204 0.0743635195692324 0.9998985119241564 0.2953503418689879 4 Q8NCH0 1 +Leber hereditary optic neuropathy 0.9355242566510124 1.7514380822110869 0.0798704780461423 0.99995010846754 0.3033538724461534 3 P03886,P00846 2 +Diabetes mellitus 0.5881220786929698 1.7272468351826726 0.0841233427791854 0.9999712523826972 0.3033538724461534 13 P31751,P13807,Q9Y5U9,P14672,P03886,Q5VV42,O76024,P49841 8 +Spinocerebellar ataxia 0.6371226051195196 1.6879080338727146 0.0914288842159216 0.9999889155995167 0.3114226584715234 9 O15020,Q9UBB4,Q8IV08,O14773 4 +FDA approved drug targets 0.3413358790088276 1.6694984157521102 0.0950186440925364 0.999993079838618 0.31408940686144 115 P14324,Q16637,Q99720,P12236,P49721,Q13423,P03886,Q7L0J3,Q8N0U8,P49356,P35610,Q16850,P12235,Q15118,P28074,P20020,Q16836,P98194,P23634,P38435,Q14534,P23786,P23458,Q96QD8,P16615,P11802,Q16739,P05141,P05023,P21964,P50416,P04035,P49354 33 +Meckel syndrome 0.7846858432695395 1.5329301453930473 0.1252930673732692 0.9999998793171204 0.3923651320373433 4 Q96J42 1 +Peroxisome biogenesis disorder 0.7425618540557324 1.4936648570497932 0.1352632383011009 0.9999999691548612 0.4127262912264363 5 P40855,O96011,O75381,P56589 4 +Parkinson disease 0.5973637461658055 1.4751555532316591 0.1401707278246131 0.999999984330508 0.417007915278224 9 Q96A57 1 +Gangliosidosis 0.7319634450175383 1.4468209731338 0.1479470711139203 0.9999999946847676 0.429407352745281 5 P07602 1 +Congenital myasthenic syndrome 0.7453429535089253 1.3653389416320023 0.1721465449349071 0.9999999998276295 0.4417900667518946 4 Q9H3H5,Q4J6C6 2 +Zellweger syndrome 0.742329367564168 1.3524602826346503 0.1762281161672552 0.9999999999042742 0.4417900667518946 4 P40855,P56589,O75381 3 +Amyloidosis 0.7417982870828661 1.350190254509379 0.1769549634092249 0.9999999999138196 0.4417900667518946 4 P03886 1 +Parkinsonism 0.5203611080154676 1.3168318824609284 0.1878949833532373 0.9999999999824672 0.4543944595746695 13 P04062,Q96A57 2 +Nephronophthisis 0.8205607254259133 1.288339385127654 0.1976278487871405 0.9999999999958245 0.4543944595746695 3 Q7Z4L5 1 +Cone-rod dystrophy 0.7384230287860089 1.2269292687918447 0.2198491766438679 0.9999999999998525 0.4756736731021869 2 Q13432 1 +Leigh syndrome 0.4736125093136694 0.9567568987980268 0.3386899716871019 1.0 0.6577118634889062 12 Q7KZN9,P00846 2 +Epilepsy 0.3269995616451772 0.9380856450177006 0.3482003983176562 1.0 0.6577118634889062 70 Q93063,Q96RL7,P03886,Q8WVX9,O75503,Q9C0E8,Q3ZCQ8,Q14108,Q9H936,Q86SQ9,Q9Y5U9,Q9H490,O14653,Q92643,P16615,O14773,P05023,P27544,Q96S52,Q13510,Q08209,P54098 22 +Emery-Dreifuss muscular dystrophy 0.6416164971951519 0.9228420698440286 0.3560895133616362 1.0 0.6621039389067923 4 P50402 1 +Rhizomelic chondrodysplasia punctata 0.667918622848168 0.6859666058251066 0.4927341668897131 1.0 0.8258502233785333 3 P50542,O15228 2 +Palmoplantar keratoderma 0.4688869224520454 0.5660086790638719 0.5713878805787456 1.0 0.870845676422111 7 P17302,Q06136 2 +Lissencephaly 0.4163268500815416 0.5642516707351461 0.5725828672744511 1.0 0.870845676422111 11 O43505,Q9Y320,Q00535,Q9H5K3 4 +Limb-girdle muscular dystrophy 0.4254276936300556 0.5050611324325307 0.6135158994362049 1.0 0.8903462443037607 8 Q9H5K3 1 +Deafness 0.2944690547319568 0.4913331774691513 0.6231908178235386 1.0 0.8930091377028577 55 Q96JX3,Q9NWM8,P51572,O60313,Q15067,Q9UG56,O75648,Q8N2K0,Q9Y287,Q9H1P3,Q9NR28 11 +Dystroglycanopathy 0.4756123917375512 0.3507205618991386 0.7257979980857174 1.0 0.9138369759304475 5 Q9H5K3 1 +Craniosynostosis 0.4949169941761452 0.3495482487951625 0.7266777549988443 1.0 0.9138369759304475 4 Q08209,P16435 2 +Congenital muscular dystrophy 0.4447173290258945 0.3316551577348313 0.740149664754254 1.0 0.9138369759304475 6 Q9H5K3 1 +Mucopolysaccharidosis 0.4681808035618267 0.3239155644157216 0.7460019600447336 1.0 0.9138369759304475 5 P08236 1 +Amyotrophic lateral sclerosis 0.349393769986282 0.320812679408477 0.748352350112202 1.0 0.9138369759304475 14 Q99720 1 +Holoprosencephaly 0.5125156445556813 0.3152502868084432 0.7525716272368392 1.0 0.9138369759304475 2 A5YKK6 1 +Progressive external ophthalmoplegia 0.4330110082050865 0.2060921276308281 0.8367189480198067 1.0 0.9536846663303706 5 P12235 1 +Leber congenital amaurosis 0.4709011264079952 0.1999924699203364 0.8414864702915035 1.0 0.9536846663303706 2 P20839 1 +Cardiomyopathy 0.2748261204247151 0.077096344290085 0.9385469011804028 1.0 1.0 29 P00846,P50402,O60313,P12235,O43819,Q9NX14 6 +Li-Fraumeni syndrome 0.3570087609511738 0.0249323112370221 0.9801089545992784 1.0 1.0 2 P04637 1 +Leukodystrophy 0.275054690122584 0.0136203909208387 0.9891328363769338 1.0 1.0 18 P07602,Q5T8D3 2 +Disease variant 0.251448031176635 0.003929698877307 0.9968645620070452 1.0 1.0 832 O43505,P14324,O14979,Q9BUK6,P07196,Q15904,Q8WWV3,O15020,O14949,O43676,Q13190,P03886,O75352,O75298,P50897,Q7Z2Z2,Q15800,Q8N511,Q9NXE4,Q9C0E8,P55263,P13473,O75844,P46977,Q4J6C6,Q3ZCQ8,P56589,P17302,P36551,P51648,Q86VD7,Q9Y276,Q96A57,P20674,Q9H2D1,Q9NZ01,O75718,Q9H5K3,Q9Y4W6,Q9NSD9,Q9UBX3,Q9H936,Q86SQ9,O14653,Q8NCH0,P13073,Q9UHX1,Q9UG56,P16615,P00846,O14773,P21912,P04062,P53701,Q10713,P07602,Q9NX62,Q13510,Q9H6K4,Q96J42,Q8N5M9,Q9H3H5,Q99720,Q7KZN9,Q9Y6M9,Q9HC21,Q9BRK0,Q96N66,Q14739,Q06136,Q5H8A4,O95470,Q96AA3,Q7RTS9,P39210,P00403,Q96A33,Q9P0J0,Q14108,Q70HW3,P17900,Q7Z4L5,Q9H490,O75845,P38435,Q9BT22,P03915,P42892,P10619,Q13432,P27544,Q969X5,Q9Y320,Q9Y287,Q9NWW5,Q01105,P49902,P50402,O43292,Q15392,Q9BV10,Q15067,O15228,P08670,P40939,Q13423,Q15041,O75503,Q8IV08,Q96RD7,P12235,O15118,Q16836,P98194,Q8N0X7,Q9BQT8,Q96JX3,Q86XL3,Q15043,P23786,Q9NVI7,Q6NUK1,Q9NQH7,Q9H0U3,O14681,P51530,Q9NX14,P16435,O75880,Q96CU9,Q16637,Q10469,Q8TAA9,O75648,Q8N2K0,Q13144,Q8NBU5,O60313,P29084,O15269,Q8TB36,Q96HR9,Q9UM00,O14678,Q9Y375,Q12769,P51798,P61619,P22830,P00367,Q8NI60,Q92643,Q2TAA5,O15460,P11802,P31751,Q9NWS8,Q9UBM7,Q9UGP8,P51812,O75306,O43819,P08236,P35637,Q53H12,P50416,Q9NR28 167 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..62dfec2647b9ffa0999c426d2bae10cccf9159b4 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atherosclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary multiple exostoses", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hyperlipidemia", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Peters anomaly", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABCB1", "ABCB7", "ABCC1", "ABCD4", "ABHD12", "ACAA1", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACY1", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADPRHL2", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKR1B1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARPC1B", "ASAH1", "ASNS", "ASPH", "ATAD1", "ATAD3A", "ATIC", "ATL3", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP8", "ATXN10", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BCAP31", "BCKDHB", "BCLAF1", "BCS1L", "BIRC6", "BLMH", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1B", "BUD23", "C12orf57", "C19orf70", "C1QBP", "CAD", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CARM1", "CARS", "CASK", "CASP2", "CBL", "CBX2", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCNB1", "CCNB2", "CCNK", "CCT5", "CDC20", "CDC27", "CDC37", "CDC42", "CDC73", "CDH2", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK6", "CDKAL1", "CEP290", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK2", "CHMP2B", "CHST14", "CISD2", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT2", "COA3", "COA7", "COASY", "COG8", "COL4A3BP", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COQ8B", "COQ9", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRTAP", "CSDE1", "CSE1L", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTDP1", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYP51A1", "DAD1", "DAG1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEGS1", "DEK", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIS3", "DKC1", "DLD", "DLST", "DNA2", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DOCK7", "DOLK", "DPAGT1", "DPM1", "DSG2", "DSP", "DST", "DTNA", "DYM", "DYNC1H1", "DYNC1I2", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "ERAL1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "FADS2", "FAF1", "FAH", "FAM120A", "FAM3C", "FAM50A", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FIP1L1", "FKBP10", "FKBP14", "FKBP5", "FKBP8", "FLAD1", "FLCN", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBE1", "GCDH", "GCLC", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GIPC1", "GJA1", "GLA", "GLB1", "GLDC", "GLE1", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNE", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GPT2", "GRB2", "GSK3A", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2E2", "GTF2H1", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYS1", "H3-3A*", "H4C1*", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGCR", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IER3IP1", "IFT27", "IGF2R", "ILF3", "ILK", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INTS1", "IPO7", "IRF2BPL", "IRS4", "ITGB1", "ITM2B", "ITPA", "IVD", "JAGN1", "JAK1", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KLC2", "KMT2A", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LGALS3BP", "LIPA", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRPPRC", "LSS", "LTA4H", "MACF1", "MAGED2", "MAGT1", "MALT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MARS", "MARS2", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MDC1", "MDH1", "MDH2", "MECP2", "MED23", "MESD", "MFN2", "MGAT2", "MICU1", "MID1", "MIF", "MIPEP", "MKI67", "MMAB", "MOGS", "MORC2", "MPDU1", "MPI", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTFMT", "MTHFS", "MTMR14", "MTOR", "MTPAP", "MTR", "MUT", "MYH10", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NAGLU", "NAMPT", "NANS", "NARS2", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCKIPSD", "NCOR1", "NCSTN", "ND1", "ND5", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEDD4L", "NEFL", "NEK9", "NF1", "NHLRC2", "NHP2", "NIPBL", "NME1", "NME2", "NNT", "NONO", "NOP10", "NOP56", "NPC1", "NPM1", "NSD1", "NSD2", "NSDHL", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OBSL1", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSBPL2", "OTULIN", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAK1", "PANX1", "PARK7", "PARN", "PARP1", "PARP2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDAP1", "PDHA1", "PDHB", "PDK1", "PDK3", "PDXK", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIN1", "PINX1", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNN", "PNP", "PNPLA6", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POMK", "POP1", "POR", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PSPH", "PTDSS1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "RAB10", "RAB18", "RAB3GAP2", "RAB7A", "RAB8A", "RAC1", "RAD21", "RAD23B", "RAD51C", "RANBP2", "RANBP3", "RARS", "RARS2", "RB1", "RBL1", "RBM10", "RBM12", "RBM15", "RBM28", "RBM7", "RBMX", "RDH11", "RDX", "REEP2", "REEP6", "RFC1", "RFC2", "RFT1", "RHEB", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS28", "RPS29", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RRM1", "RRM2", "RTN2", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SART1", "SBDS", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SDHA", "SDHB", "SEC23A", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEPT2", "SEPT9", "SERAC1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SHOC2", "SIGMAR1", "SIN3A", "SIRT2", "SKIV2L", "SKP2", "SLC12A2", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A4", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC9A3R1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRP54", "SRP72", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAT1", "STAT3", "STIM1", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "SUCLA2", "SUCLG1", "SUZ12", "SV2A", "SYNE2", "TAF15", "TALDO1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL2", "TCEA1", "TCOF1", "TEAD1", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM50", "TIMMDC1", "TJP2", "TK1", "TKT", "TMCO1", "TMEM199", "TMEM230", "TMEM38B", "TMEM43", "TMEM70", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TP53", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPX2", "TRAF2", "TRAPPC11", "TRIM25", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSG101", "TTC19", "TTC21B", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP4", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNDC15", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBA5", "UBE2N", "UBE3A", "UBQLN4", "UBR5", "UBTF", "UFC1", "UFM1", "UGCG", "UGDH", "UGP2", "UMPS", "UNC119", "UPF3B", "UQCC2", "UQCRB", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USP9X", "UTP4", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS13C", "VPS13D", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WDR1", "WDR36", "WDR4", "WDR45B", "WDR5", "WFS1", "WIPI2", "XPNPEP3", "XPO1", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YEATS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZCCHC8", "ZMPSTE24", "ZMYM2"], "leading_proteins": ["ABCD4", "ABHD12", "ACBD5", "ACOX1", "ADK", "AFG3L2", "AGK", "AKT2", "ALDH3A2", "ALG1", "ALG11", "ALG12", "ANKLE2", "ARL6IP1", "ASAH1", "ATAD1", "ATAD3A", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP6", "ATP6AP1", "ATXN10", "B4GALT1", "B4GAT1", "BCAP31", "BCS1L", "C19orf70", "CCDC47", "CDK4", "CDK5", "CDKAL1", "CERS1", "CHST14", "CLCN7", "CLN5", "CLN6", "CNOT1", "COA3", "COMT", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPT1A", "CPT2", "CRTAP", "CTSA", "CYP51A1", "DHCR24", "DHCR7", "DHDDS", "DIABLO", "DNA2", "DPAGT1", "DYM", "ECE1", "EFL1", "EI24", "EIF2B5", "EMD", "ERGIC1", "EXT2", "FAR1", "FARSB", "FDPS", "FECH", "FKBP14", "FNTA", "FNTB", "FOXRED1", "FUS", "GBA", "GDAP1", "GGCX", "GJA1", "GLUD1", "GM2A", "GNPAT", "GOSR2", "GPAA1", "GSK3B", "GTF2E2", "GUSB", "GYS1", "HADH", "HADHA", "HCCS", "HMGCR", "HNRNPDL", "IER3IP1", "IMPAD1", "IMPDH1", "ITM2B", "JAGN1", "JAK1", "KDSR", "KLC2", "LAMP2", "LBR", "LEMD2", "LNPK", "LSS", "MAGT1", "MBOAT7", "MGAT2", "MPDU1", "MPV17", "MSMO1", "MSTO1", "ND1", "ND5", "NDUFA11", "NDUFA13", "NDUFAF1", "NDUFB11", "NDUFB3", "NDUFB9", "NDUFS2", "NEFL", "NNT", "NPC1", "NT5C2", "NUP160", "OPA1", "OPA3", "OSBPL2", "P4HA2", "PANX1", "PDK1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PIGG", "PIGK", "PIGS", "PIGU", "PISD", "PLD3", "PMPCA", "POLG", "POMK", "POR", "PPP3CA", "PPT1", "PREPL", "PSAP", "PSMB2", "PSMB5", "PUF60", "RAB10", "RDH11", "REEP2", "REEP6", "RFT1", "RMND1", "RPS6KA3", "RTN2", "RTN4IP1", "SC5D", "SCARB2", "SCO1", "SCO2", "SDHB", "SEC61A1", "SEC63", "SERAC1", "SET", "SFXN4", "SGPL1", "SIGMAR1", "SIRT2", "SLC25A10", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC2A4", "SLC38A2", "SLC39A14", "SLC44A1", 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sha256:10097f0ce7ab5798c5985e6c97237a0803ff5e730cdb34fa0ef1d6ed9712f665 +size 86856 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0de87efd1ca4940d2c2a44cc4c00cdb4bbddd74c --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 15 40 3.5381176627651167 0.0004029904360423 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.0988426938622822 0.3389463545940903 0.4263093585963844 0.150944712575361 0.1521056179626394 +Glycosyltransferase 16 42 2.966403657542612 0.0030130474490663 8.383495145631068 33.63106796116505 0.9005425082235603 0.4380439374186179 3.633517034002208 4.6602851932859135 0.9766631781348049 0.3531801259598526 0.0057954665024801 0.4382064719922659 0.6815201720499937 0.160244095486996 0.0005827697807827 +Oxidoreductase 45 169 2.196869711326021 0.0280297525846455 36.64563106796116 165.7621359223301 0.5091071251362119 0.5527126631147542 14.160338956360992 12.210799107974529 1.1772957028589783 0.3900527505954884 5.8171297655192343e-08 0.0259491863368797 0.0018075694638971 3.944353434185604e-05 1.163417414432408e-07 +Translocase 13 25 2.164938413849587 0.0303924019268841 8.031553398058252 23.23543689320388 0.8266305625937611 0.3429767730570308 3.903132239147793 3.2553774114037415 1.2917497354360188 0.3272657999875639 0.000418780120155 0.2516504230112798 0.1112999318055074 0.0145897333531984 2.343047607375844e-05 +Protease 28 76 2.0512741404783297 0.0402402573136857 20.788834951456312 82.44417475728156 1.1215350835872162 0.3507517256058336 6.07090559629836 8.079357013764625 1.4678877461728397 0.3691345771929886 0.265871082780108 0.3034250453076603 0.647227301003383 0.3199581089454296 0.0901830311785445 +Ion channel 5 13 2.0254571938521013 0.0428204396908915 3.3106796116504853 9.844660194174756 0.0369546464975766 0.4589231045677855 2.1923482388215443 2.4035058598872987 1.0709210139105 0.2964139590710569 0.165614181021796 1.0 0.4153631372956372 0.3929907866903629 0.1320169004577724 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..78c1b43c5d3b79e0baba4e649b0c930361114063 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 91, + "title": "Average number of proteins per term", + "value": 40.94505494505494 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..117234e9093812695330c7e3fde6ad2c3031b933 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e4742c21b6ddefd1f89ce7a132978ad4bdb39f6a --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,25 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.6242302585868694 3.5381176627651167 0.0004029904360423 0.0360149771205758 0.0091680324199624 40 Q99720,P24390,Q99623,O15173,Q9UBG0,P35613,Q9NS69,O15118,Q9Y5M8,Q14108,O00264,Q14739,Q8WTV0,P11279,P30825 15 +Glycosyltransferase 0.549263640482706 2.9664036575426116 0.0030130474490663 0.2401249135741464 0.0304652575405601 42 O43505,Q9H3H5,P43490,P04062,Q9BT22,Q8N4A0,P15291,Q10469,Q9BV10,P46977,Q16739,Q11206,Q16880,Q2TAA5,Q8TCJ2,Q10472 16 +Oxidoreductase 0.3507536952971395 2.196869711326021 0.0280297525846455 0.9247649226537916 0.1535280152124035 169 Q96CU9,Q8NBM8,O00767,Q9Y6N5,Q9HBH5,Q15392,Q9UHQ9,Q15067,P40939,Q14739,Q06136,Q15800,Q8N0U8,Q8NBN7,P09601,Q9UHG3,P30519,Q16850,Q8NBX0,P51648,Q53GQ0,Q16836,Q9NZ01,Q9NRG7,Q6UW02,O75845,Q658P3,Q14534,P13073,O15254,P00367,Q709F0,Q8N4Q0,O15460,Q32P28,Q9Y394,Q99735,Q9UBM7,P21912,P78417,O75306,Q8TED1,Q8NBQ5,P04035,P16435 45 +Translocase 0.5465929018418411 2.164938413849587 0.0303924019268841 0.9397111615982816 0.1536504764081367 25 Q8NBU5,P03886,P08183,P00403,Q9HD20,P05023,O75306,Q03519,P03915,Q13423,P20020,P98194,P16615 13 +Protease 0.4097600860570549 2.0512741404783297 0.0402402573136857 0.9761883123916744 0.1759167122844363 76 P67812,P09960,Q9UIQ6,P55786,Q9HB40,Q6P179,Q9H8M7,Q70CQ2,O75844,Q4J6C6,P51784,Q7Z2K6,P28074,Q9NZ08,Q9H300,Q9Y4W6,Q96FZ2,Q92643,O00487,Q9NQH7,P42892,O14773,P10619,Q92905,P28072,P42785,P53634,Q15005 28 +Ion channel 0.6390915539024321 2.0254571938521013 0.0428204396908915 0.981361933226696 0.1771209096305059 13 Q96RD7,Q96S66,Q9UM00,Q4KMQ2,Q9C0H2 5 +Porin 0.8891671884783854 1.9697386441382327 0.048868331634758 0.9895311634941576 0.1873521504087173 4 Q9Y277,P45880,P21796 3 +Prenyltransferase 0.8116014744132878 1.646779358494376 0.0996034055808141 0.9999286359027804 0.2923841905759383 4 P53611,P49356 2 +Metalloprotease 0.4689034348399086 1.5662009588833117 0.1173015783163526 0.9999882801014052 0.3335763633371279 25 Q6P179,P42892,P09960,Q9UIQ6,Q92905,O75844,Q7Z2K6,Q9NZ08,O00487,Q9Y4W6,Q9NQH7 11 +Monooxygenase 0.8803951207632127 1.5301922949730613 0.1259691380049332 0.99999522541233 0.347369441165119 3 Q6UW02 1 +Chloride channel 0.7360088665920872 1.4647149729269529 0.1429986981249347 0.9999992032632838 0.3745564163034404 5 Q96S66,Q9C0H2 2 +Host cell receptor for virus entry 0.4791837553513389 1.431481835432376 0.152292169266234 0.9999997046045892 0.3745564163034404 18 O15118,Q8WTV0,Q14108,P11279 4 +Calcium channel 0.8137187225987054 1.2606719871645704 0.2074270506453015 0.9999999993505116 0.4839964515057036 3 Q96RD7 1 +Transferase 0.2693856946288838 1.0192962383750783 0.3080623492780712 0.9999999999999972 0.5710612382302291 374 O43505,P14324,Q9H3H5,P43490,Q8N4A0,Q9HCL2,Q10469,Q9BV10,O60858,Q9BRR6,Q11206,Q8NF37,Q9Y6K0,O15228,Q96N66,P40939,O75648,Q5H8A4,Q5VV42,Q7LGA3,P49356,P35610,O14735,P46977,O15269,Q96G23,Q86Y07,Q9BV86,Q9BVG9,Q8TCJ2,Q16836,O95674,Q9H5K3,Q86VU5,Q8NCH0,Q9BT22,Q969V5,Q9UKV5,O60725,Q8NI60,Q96PU5,P23786,Q8IXJ6,Q2TAA5,P37268,P52789,Q6UX53,Q92604,P23458,P11802,P31751,Q99735,P78417,P04062,P53611,P51812,P15291,Q16739,P21964,P27544,Q86UL3,Q16880,Q53H12,P50416,Q9H1A3,P49354,O15498,Q10472 68 +Guanine-nucleotide releasing factor 0.4564021818150072 0.8531412614746532 0.3935809721804451 1.0 0.6295995848554236 12 P80303 1 +Acyltransferase 0.3408165718828312 0.8523319581996034 0.3940298732373837 1.0 0.6295995848554236 36 P35610,Q9HCL2,O15269,Q86UL3,Q8NF37,P23786,O15228,Q96N66,Q92604 9 +Glycosidase 0.3976710163394438 0.8391967574008327 0.4013589066262435 1.0 0.6295995848554236 18 P04062,Q16706,O60502,P08236,Q9BTY2 5 +Serine protease 0.4719718184873724 0.8337089912801231 0.4044449902087992 1.0 0.6295995848554236 10 O14773 1 +Threonine protease 0.704928689259588 0.8270619865699999 0.4082019286425273 1.0 0.6295995848554236 3 P28074 1 +Cytokine 0.5661416528892322 0.6129330055480752 0.5399206383843058 1.0 0.7630231666473338 4 P43490 1 +Carboxypeptidase 0.4661527929343008 0.4176342782079743 0.6762145306788525 1.0 0.8075344803258715 6 P10619,P42785 2 +Voltage-gated channel 0.4879300447800002 0.3964194555446779 0.6917956157913576 1.0 0.8075344803258715 5 Q4KMQ2 1 +Lyase 0.2883220507572152 0.3459752045672002 0.7293613492320974 1.0 0.8194059602484057 39 Q99735,P38435,P53701,Q9UG56,Q9P035,P40939,O95470 7 +Methyltransferase 0.2806980584049663 0.2905545215862799 0.7713920465592494 1.0 0.8370792981298965 42 Q86VU5,P04818,Q08J23,Q86X55,O60725,P21964,Q9BV86,Q9H1A3,Q6UX53 9 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c1aa20ba5e6a1297de8c99031065647e1a9d9cbb --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCC1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD16A", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ACY1", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADSL", "ADSS", "AFAP1", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG5", "ALKBH5", "AMFR", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "APEH", "APEX1", "APRT", "AQR", "ARFGAP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAP18", "BAZ1B", "BCKDHB", "BCLAF1", "BCS1L", "BEND3", "BIRC6", "BLMH", "BLVRA", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BSG", "BTAF1", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "CAD", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2D", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CBL", "CBR1", "CBX2", "CBX3", "CCAR1", "CCAR2", "CCDC47", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC37", "CDC42", "CDC5L", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPU", "CEP290", "CEPT1", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHKA", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT2", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPS5", "COQ8A", "COQ8B", "CORO1B", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CROT", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCPS", "DCTD", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHPS", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNA2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC19", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DRG1", "DRG2", "DST", "DSTN", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERMP1", "ERO1A", "ERP44", "ESD", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "F11R", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLYWCH1", "FMR1", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDI1", "GDI2", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GGH", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HTRA2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "ING5", "INTS11", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISG20L2", "ISYNA1", "ITGB1", "ITPA", "IVD", "JAK1", "JMJD6", "KARS", "KAT7", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "LACTB", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD3", "LIG1", "LIG3", "LIMA1", "LIPA", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "MACF1", "MAGED2", "MALT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPK14", "MARC1", "MARCH5", "MARCKS", "MARS", "MARS2", "MAT2A", "MATR3", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED14", "MED16", "MED18", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METTL1", "METTL3", "METTL7B", "METTL9", "MFN1", "MFN2", "MGAT2", "MGEA5", "MGST1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPRIP", "MPST", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTFMT", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTOR", "MTPAP", "MTR", "MTSS1L", "MUL1", "MUT", "MYBBP1A", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NARS2", "NAT10", "NAXE", "NCBP3", "NCEH1", "NCL", "NCOA5", "NCOR1", "ND1", "ND5", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEK9", "NELFA", "NELFCD", "NF1", "NFRKB", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OTUB1", "OTULIN", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM7", "PDXDC1", "PDXK", "PEBP1", "PECR", "PELO", "PELP1", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF5A", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PIGG", "PIGK", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR2H", "POLR3A", "POLR3C", "POLRMT", "POMK", "PON2", "POP1", "POR", "PPA1", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R8", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKCA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS1", "PRPS2", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", 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"RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPP38", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAP130", "SAP18", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORT1", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", 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0000000000000000000000000000000000000000..f56c22adf83024635700f820efd65420d572e772 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a25124122e677c28adedf0ed889a7e0e64812352b9735ce04523092afb53723b +size 101961 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f48c3c55c3a19f5c7929fbbd4d3d58e4c52cbd7b --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 365 637 10.254917503334235 1.124720013340668e-24 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 4.977577280534321e-89 1.3628229455487774e-15 2.02666399898498e-30 3.2632514369733245e-62 1.6518085839157743e-99 +Transporters 162 381 7.118075215252507 1.0944464539988597e-12 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 3.8457181538522535e-31 0.0120254404772823 3.572299518010589e-07 4.618422241684513e-15 1.3101485235864118e-35 +Metabolic proteins 211 900 2.6382794095866338 0.0083327893360722 167.96116504854368 885.0898058252427 0.3517504365488901 0.4992811695371688 49.08590099318301 81.73901275864796 1.4937513760737942 0.4046478208580187 7.386283986602246e-11 0.0102400115360288 0.0051660588923439 1.0944471897946334e-06 3.2418267163437374e-11 +Predicted secreted proteins 21 55 2.33668095666142 0.0194557794542931 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 0.4542255616296909 0.3722219383147173 0.0429800365153788 0.2025976132356922 0.6525401764397545 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9567518a532285132b08179d877936105f0ea1e9 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 20, + "title": "Average number of proteins per term", + "value": 516.2 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4804d6421d5e0c0d3ac8d18ddb34e5c2818c2cc8 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2b3c3e424d5a49bcb945b8b4fa69a5cc0966a880 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.7233924328495185 10.254917503334235 1.124720013340668e-24 2.0000022494400268e-17 6.66667416480009e-18 637 O43169,P67812,Q9Y2R0,Q9NQC3,Q99595,O43657,P43307,O95197,P24390,Q9HCL2,Q96A26,O60637,O60858,Q96RQ1,Q8NCG7,O43676,Q567V2,O96005,P03886,Q86Y39,O75298,Q9H1E5,Q9H6V9,Q9BUR5,Q15800,Q8N511,Q8N0U8,Q8N4V1,P09601,Q9UDX5,P30519,O75844,P46977,Q86YN1,Q96G23,Q9NS69,Q8N8Q8,P51648,Q86VD7,Q96A57,Q9Y282,Q9NZ01,O95674,Q9H5K3,Q9H061,Q6UW02,Q9UBX3,Q15629,Q4ZIN3,O75071,O75964,O14653,Q5VW38,Q8NCH0,Q92543,Q14534,Q969V5,P13073,O60725,Q9UG56,Q9Y5M8,P57105,O00461,Q86UE4,Q9P2W9,Q9NZJ7,Q15070,Q13505,Q8TAD4,Q9C0H2,Q9H2V7,P16615,Q93050,Q7Z3D4,P00846,O14925,O15173,Q96JJ7,O95070,Q9NX62,Q9H4I3,Q9H6K4,O00264,Q96J42,Q6NTF9,Q8N5M9,Q9Y6C9,Q15005,Q9Y3E0,Q9H3H5,O00767,Q8NHH9,Q99720,O95298,Q7KZN9,Q9BXS4,Q9NPA0,Q9NX40,Q6NUK4,Q11206,Q8NF37,O60499,Q9HC21,Q9Y6K0,Q9BRK0,Q96N66,Q14739,Q06136,Q5H8A4,O95470,Q5VV42,Q96AA3,Q7RTS9,P39210,P00403,Q9H6H4,Q96A33,Q9HD20,Q8N2H4,Q96ES6,Q9Y241,Q6P4A7,Q9P0J0,Q9P035,Q9HD45,Q14108,Q53GQ0,Q70HW3,Q9H3K2,Q9BVG9,Q9H300,Q9NVH1,Q3SXM5,P30825,Q8N2F6,Q8IWB1,Q9BXK5,Q9H490,O75845,P38435,Q96PC5,Q9BT22,Q16799,Q96S66,Q96KC8,P56378,Q13641,P03915,O14828,O15258,P37268,O94901,Q8WVC6,Q96QD8,P42892,Q9Y3A6,Q9NPR9,Q99735,Q96BY9,P55061,Q8TB61,Q9UBV2,Q8N8L6,P27544,Q969X5,Q9Y320,O95249,Q12981,Q6UW68,Q9H3N1,Q9UDW1,P04035,Q9Y287,Q9NWW5,Q8WTV0,Q10472,Q92544,Q9P0S9,P50402,Q07820,Q8NBM4,Q9Y487,O43292,Q15392,Q9BV10,Q07065,Q9BVK6,Q8NC54,Q96SK2,Q08722,Q9Y3B3,Q13423,Q4KMQ2,Q96AG4,Q15041,Q7L0J3,Q96IX5,P41440,Q00765,Q9BSR8,Q9NQX7,Q9Y2G8,P08183,Q5SNT2,P51572,Q8IV08,Q96RD7,O14735,Q9NR77,Q16850,P12235,O15118,P24539,Q8NBX0,Q5T8D3,Q9BTX1,Q96KA5,Q8TCJ2,P98194,P11279,P49755,Q8N2A8,Q96JX3,Q9H2J7,Q9BSK2,Q86XL3,Q9GZP9,P35613,Q03519,Q9BU23,Q6Y1H2,Q15043,Q92604,Q7Z3C6,P57088,O43808,O75381,Q9H0U3,P56134,O14681,Q16739,Q9UBG0,Q9Y6M7,Q86UL3,Q16880,Q8IXM6,Q92804,Q9NX14,Q8IWA4,P49257,P16435,O15260,Q96TC7,O75880,O60831,Q96NB2,Q9UIQ6,Q969V3,Q9NTJ5,P12236,Q8TBA6,Q9BUB7,Q8TAA9,Q9Y6N1,O95202,Q6PI78,P51571,Q8N2K0,Q6PIU2,Q8IXU6,Q8NBU5,Q9NPL8,Q9UBU6,Q96GQ5,Q70UQ0,P51790,Q96CS3,P35610,O15269,P11117,Q7Z2K6,Q8IYS2,Q8TB36,Q96HR9,Q9UM00,Q86Y07,O14678,Q14789,Q99442,P51798,P61619,Q658P3,Q86VR2,Q9UKV5,Q15363,Q92643,Q2TAA5,O15400,Q3ZAQ7,Q9NWS8,Q12770,Q9UBM7,Q9UGP8,Q8NAN2,P51812,P27824,P15291,P05141,P05023,O75306,O43819,A1L0T0,Q9Y2W6,P50416,Q9NR28,Q8TBP6,Q9BVC6,Q15904,Q8WUK0,Q99640,Q9UNK0,O95139,Q13190,O75352,O14683,P15151,Q8WWI5,Q9NXE4,O43760,Q9C0E8,P13473,Q9BRX8,Q7Z434,Q3ZCQ8,P56589,P17302,P36551,Q9Y276,P20020,O94919,Q9Y4W6,Q9H936,P23634,Q16706,Q8WVQ1,Q15631,O75027,Q9UH99,Q9H9B4,P04439,O95563,P49841,O43731,O14975,Q8NE00,Q14012,O95169,Q8NC56,Q5JRA6,P53634,Q92896,Q9BZF1,Q13586,Q9Y679,Q93063 365 +Transporters 0.5615607292574802 7.118075215252507 1.0944464539988597e-12 2.188894907974961e-11 5.472237269994298e-12 381 Q8TBP6,Q9BVC6,P24390,Q15904,O60637,P45880,Q13190,O96005,Q7Z3B4,Q9BUR5,Q8WWI5,Q8N511,Q9C0E8,Q8N4V1,P13473,O75844,P46977,P56589,Q8N8Q8,Q9Y276,Q86VD7,Q96A57,P20674,Q9H2D1,P20020,Q9H061,Q9H936,Q9UBX3,Q15629,P23634,Q5VW38,P13073,O75027,P57105,Q9NZJ7,Q9Y3C0,Q15070,Q9UH99,Q9H9B4,Q8TAD4,Q9C0H2,Q9H2V7,P16615,P04439,Q93050,O95563,Q9HD26,Q96HE7,O14975,P21912,Q96JJ7,P07602,Q6NTF9,Q9Y6C9,Q8NHH9,Q99720,Q9BXS4,Q9NPA0,Q9HC21,Q9Y6K0,Q96N66,Q96AA3,P40855,P39210,P00403,Q9Y371,Q96A33,Q9HD20,Q6P4A7,Q14108,Q70HW3,Q9H300,P30825,Q96PC5,Q16799,Q96S66,O14828,O15258,O94901,Q96QD8,Q96BY9,P55061,Q8TB61,Q9UBV2,Q9Y320,Q6UW68,Q9H3N1,P04035,Q9Y287,Q9NWW5,Q8WTV0,Q92544,Q07065,Q08722,Q9Y3B3,Q4KMQ2,Q96AG4,P41440,P08183,P51572,Q96RD7,Q9NR77,P12235,O15118,O75340,Q5T8D3,Q9BTX1,Q8TCJ2,P98194,P11279,P49755,Q9BQT8,Q9H2J7,Q9BSK2,Q9GZP9,P35613,Q03519,O43681,Q15043,Q6NUK1,Q7Z3C6,P57088,O43808,O75381,O96008,Q9H0U3,O14681,Q16739,Q9Y6M7,Q9NQZ5,Q8IWA4,P49257,O15260,O60831,Q96NB2,Q969V3,Q8NFH5,P12236,Q8TBA6,Q9BPX6,Q9BUB7,Q9Y512,Q8TAA9,O95202,Q16891,Q9BRK5,Q8IXU6,Q9UBU6,O60313,Q9UM00,O14678,O15504,Q99442,Q12769,P51798,P61619,Q658P3,Q15363,Q9UGP8,P05141,P05023,P50416 162 +Metabolic proteins 0.3130754964010249 2.6382794095866338 0.0083327893360722 0.154099908953952 0.0208319733401807 900 O43505,P67812,P14324,P14174,Q13126,O96000,Q9HCL2,Q15904,Q9HBH5,Q9UHQ9,Q8WUK0,Q9BRR6,O14949,Q99640,O95139,Q8NCG7,O43676,Q7Z3B4,P03886,Q86Y39,P50897,Q7Z2Z2,Q15800,Q8WWI5,Q9NXE4,P09601,Q9UHG3,P55263,P30519,O75844,P46977,Q86YN1,Q96G23,Q70CQ2,Q15118,P36551,P51648,Q86VD7,P20674,Q9H2D1,P20020,Q9NZ01,O95674,Q9NSD9,Q9H936,Q9UBX3,Q86SQ9,P15586,P23634,O75964,P04818,Q8NCH0,Q16706,Q14534,Q969V5,P13073,O60725,Q9UG56,Q15165,P16615,Q93050,P00846,O14773,P21912,P04062,P53701,Q10713,Q96JJ7,P21964,Q9Y680,P07602,P36542,Q9NX62,Q13510,Q15005,Q9H3H5,O00767,O95298,Q9Y6M9,Q11206,Q8NF37,Q9HC21,Q9Y6K0,Q96N66,Q14739,Q06136,Q5H8A4,O95470,Q7LGA3,Q8NBN7,P49356,P00403,Q9Y371,Q9P0J0,Q9P035,Q53GQ0,Q70HW3,P17900,Q9BVG9,P30825,Q9H490,O75845,Q9NWM8,Q9BT22,P56378,P03915,Q9NPH0,Q96PU5,Q8N4Q0,P37268,P52789,Q96QD8,Q99735,P10619,Q8TB61,P27544,Q9UDW1,P04035,Q8WTV0,Q10472,P09960,P49902,P43490,Q8NBM4,Q9Y487,O43292,Q15392,Q9BV10,Q15067,Q9H7Z7,O15228,P40939,Q13423,Q96IX5,P41440,P08183,P51572,Q8IV08,O14735,Q16850,P12235,O15118,P24539,Q8NBX0,Q9BTX1,Q8TCJ2,Q16836,P98194,Q9BQT8,Q8N2A8,Q9H2J7,Q86VU5,P56385,O15254,Q6Y1H2,Q709F0,Q15043,P23786,Q8IXJ6,P07099,Q6UX53,Q92604,O43808,P56134,Q16739,Q9Y6M7,Q86UL3,Q9NQZ5,Q16880,Q8TED1,Q9NX14,P16435,Q8NFH5,Q9NTJ5,P12236,Q8N4A0,Q10469,P51571,O75648,Q8N2K0,Q9BTY2,P35610,O60502,O15269,P11117,P51784,Q86Y07,O15504,Q12769,Q9UKV5,P22830,P00367,Q92643,Q2TAA5,O15460,P23458,P11802,P31751,Q9UBM7,P78417,P51812,P15291,P05141,P05023,O75306,P08236,Q8NBQ5,Q53H12,P50416,P49354,O15498 211 +Predicted secreted proteins 0.4581112284177075 2.33668095666142 0.0194557794542931 0.3249379641311856 0.0389115589085862 55 P14174,Q9UM22,Q8NBM8,P43490,P15151,Q9BTY2,Q6P179,Q9BUR5,Q9BRX8,Q9NZ08,Q92520,P84157,P80303,O75718,O94919,Q14667,Q8N128,Q02818,Q15165,Q9Y4P3,Q9Y287 21 +FDA approved drug targets 0.3413358790088276 1.6694984157521102 0.0950186440925364 0.8642334936786881 0.1386154794920245 115 P14324,Q16637,Q99720,P12236,P49721,Q13423,P03886,Q7L0J3,Q8N0U8,P49356,P35610,Q16850,P12235,Q15118,P28074,P20020,Q16836,P98194,P23634,P38435,Q14534,P23786,P23458,Q96QD8,P16615,P11802,Q16739,P05141,P05023,P21964,P50416,P04035,P49354 33 +Potential drug targets 0.3071359363799825 1.5164345063363212 0.1294095193211426 0.937442658736084 0.1712908346979214 500 P14174,Q13126,Q15904,P50897,Q15800,Q8N511,Q8WWI5,Q9NXE4,Q9C0E8,P09601,P55263,P13473,O75844,P46977,Q4J6C6,P56589,P36551,P51648,Q86VD7,Q9Y276,P20674,Q9H2D1,Q9NZ01,Q9Y4W6,Q9H5K3,Q9H061,Q9NSD9,Q9H936,Q86SQ9,P15586,Q8NCH0,Q8WVQ1,P13073,O75027,Q8TC12,P04439,O14773,P21912,P04062,P53701,Q10713,P07602,Q9NX62,Q13510,Q9H3H5,Q9HC21,Q96N66,Q14739,Q06136,O95470,Q5VV42,Q96AA3,P40855,P39210,P00403,Q96A33,Q6P4A7,Q14108,Q70HW3,O75845,Q96PC5,Q9NWM8,Q9BT22,Q96S66,P03915,Q96PU5,P37268,Q32P28,P42892,P10619,Q9Y320,Q9Y287,Q9NWW5,P49902,Q15392,Q9BV10,Q15067,O15228,P40939,Q4KMQ2,P51572,Q8IV08,Q96RD7,O15118,Q5T8D3,Q8TCJ2,Q9BQT8,Q03519,Q15043,P07099,Q6NUK1,Q9NQH7,O75381,Q9H0U3,O14681,P51530,P49257,P16435,Q10469,Q8TBA6,Q9BPX6,Q9BUB7,Q8TAA9,O75648,Q8N2K0,O60313,O15269,P11117,Q9UM00,O14678,Q12769,P51798,P61619,Q658P3,P22830,P00367,Q8NI60,Q92643,Q2TAA5,O15460,P31751,Q9UBM7,Q9UGP8,P51812,P15291,O75306,P08236,Q53H12 128 +CD markers 0.4869645469009787 1.4869323930618097 0.1370326677583371 0.9475328933979515 0.1712908346979214 18 Q8WWI5,P15151,P08183,Q9UBG0,P35613,Q08722,P11279 7 +Human disease related genes 0.2604162562997448 1.1626168936845975 0.2449849734573945 0.996376636513152 0.2882176158322289 947 O43505,P14324,P14174,O14979,O96000,P07196,Q8WWV3,O15020,O14949,O43676,P03886,Q86Y39,O75352,O75298,P50897,Q7Z2Z2,Q15800,Q8N511,Q5XKP0,Q9NXE4,Q9C0E8,P09601,P55263,P13473,O75844,P46977,Q4J6C6,Q3ZCQ8,P56589,P17302,P36551,P51648,Q9Y276,Q9NZ01,O75718,Q9H5K3,Q9H061,Q9Y4W6,Q9UBX3,Q9NSD9,Q9H936,Q86SQ9,P15586,O14653,Q8NCH0,Q9UHX1,P16615,Q9H0B6,P00846,O14773,P21912,P04062,P53701,Q10713,P21964,P07602,Q9NX62,Q13510,Q9H6K4,Q9H3H5,Q99720,Q7KZN9,Q9Y6M9,Q9HC21,Q9BRK0,Q96N66,Q14739,Q06136,Q5H8A4,O95470,Q5VV42,Q96AA3,P40855,Q7RTS9,P39210,P00403,Q6P4A7,Q9P0J0,Q14108,Q70HW3,P17900,Q7Z4L5,Q9H490,O75845,P38435,Q9NWM8,Q9BT22,P03915,Q96PU5,Q32P28,P42892,Q6DKK2,P10619,P27544,Q969X5,Q9Y320,Q9Y287,Q9NWW5,Q01105,P49902,P50402,Q9Y487,O43292,Q15392,Q9BV10,Q15067,Q9H7Z7,O15228,P08670,P40939,Q13423,Q4KMQ2,Q15041,Q96IX5,O75503,Q9Y2G8,P08183,P51572,Q8IV08,Q96RD7,Q9NR77,P12235,O15118,Q8TCJ2,Q16836,P98194,Q8N0X7,Q9BQT8,Q96JX3,Q86XL3,Q03519,Q15043,P23786,Q9NVI7,P07099,Q6NUK1,Q9NQH7,O75381,Q9H0U3,Q9NQZ5,P51530,Q9NX14,P49257,P16435,O75880,Q96CU9,Q16637,Q10469,Q9BPX6,Q9BUB7,Q8TAA9,O95202,P51571,O75648,Q8N2K0,Q13144,Q8NBU5,Q9NPL8,O60313,P29084,O15269,P11117,Q8TB36,Q96HR9,Q9UM00,O14678,Q9Y375,Q12769,P51798,P61619,Q9UBB4,P22830,P00367,Q8NI60,Q92643,Q2TAA5,O15460,Q9H1P3,Q3ZAQ7,P11802,P31751,Q9NWS8,Q9UBM7,Q9UGP8,P51812,P15291,P05023,O75306,O43819,P08236,P35637,Q9Y4P3,Q53H12,P50416,Q9NR28 195 +Disease related genes 0.2548241167028847 0.8349906105086279 0.4037229950662135 0.9999677179409762 0.4485811056291262 1039 O43505,P14324,Q9Y2R0,P14174,O14979,Q13126,Q9BUK6,P07196,Q15904,Q8WWV3,O15020,O14949,O43676,P03886,Q86Y39,O75352,O75298,P50897,Q7Z2Z2,Q15800,Q8N511,Q5XKP0,Q8WWI5,Q9NXE4,Q9C0E8,P09601,P55263,P13473,O75844,P46977,Q4J6C6,Q3ZCQ8,P56589,P17302,P36551,P51648,Q86VD7,Q9Y276,P20674,Q9H2D1,Q9NZ01,O75718,Q9H5K3,Q9H061,Q9Y4W6,Q9NSD9,Q9H936,Q86SQ9,P15586,O14653,Q8NCH0,P13073,Q9UHX1,P16615,Q9H0B6,P00846,O14773,P21912,P04062,P53701,Q10713,P21964,P07602,Q9NX62,Q13510,Q9H6K4,Q96J42,Q8N5M9,Q9H3H5,Q99720,Q7KZN9,Q9Y6M9,Q9HC21,Q9BRK0,Q96N66,Q14739,Q06136,Q5H8A4,O95470,Q5VV42,Q96AA3,P40855,Q7RTS9,P39210,P00403,Q96A33,Q6P4A7,Q9P0J0,Q14108,Q70HW3,P17900,Q7Z4L5,Q9H490,O75845,P38435,Q96PC5,Q9NWM8,Q9BT22,Q96S66,P03915,Q96PU5,P37268,Q32P28,P42892,Q6DKK2,P10619,Q13432,P27544,Q969X5,Q9Y320,Q9Y287,Q9NWW5,Q01105,P49902,P50402,Q9Y487,O43292,Q15392,Q9BV10,Q15067,O15228,P08670,P40939,Q13423,Q4KMQ2,Q15041,Q96IX5,O75503,P08183,P51572,Q8IV08,Q96RD7,P12235,O15118,Q5T8D3,Q8TCJ2,Q16836,P98194,Q8N0X7,Q9BQT8,Q96JX3,Q86XL3,Q03519,Q15043,P23786,Q96DH6,Q9NVI7,P07099,Q6NUK1,Q9NQH7,O75381,Q9H0U3,O14681,P51530,Q92804,Q9NX14,P49257,P16435,O75880,Q96CU9,Q16637,Q10469,Q8TBA6,Q9BPX6,Q9BUB7,Q8TAA9,Q6PI78,P51571,O75648,Q8N2K0,Q13144,Q8NBU5,Q9NPL8,O60313,P29084,O15269,P11117,Q8TB36,Q96HR9,Q9UM00,O14678,Q9Y375,Q12769,P51798,P61619,Q658P3,Q9UBB4,P22830,P00367,Q8NI60,Q92643,Q2TAA5,O15460,Q9H1P3,Q3ZAQ7,P11802,P31751,Q9NWS8,Q9UBM7,Q9UGP8,P51812,P15291,P05023,O75306,O43819,P08236,P35637,Q9BS16,Q9Y4P3,Q53H12,P50416,Q01844,Q9NR28 213 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..85b200049c6a9f865732e3dce1e12654200ab8c4 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD16A", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD11", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG12", "ALG5", "ALKBH5", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARPC5", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATP8", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B3GALT6", "B4GALT1", "B4GAT1", "BABAM1", "BABAM2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCCIP", "BCKDHB", "BCL2L12", "BCL2L13", "BCLAF1", "BCS1L", "BEND3", "BET1", "BIRC6", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C19orf70", "C1QBP", "C1orf35", "C2CD2", "C2CD5", "C2orf49", "C5orf15", "C8orf33", "C9orf64", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC97", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPI", "CENPK", "CENPU", "CENPV", "CEP170", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG8", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD7", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COPZ1", "COQ8A", "COQ8B", "COQ9", "CORO1B", "CORO1C", "COTL1", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DGUOK", "DHCR24", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHPS", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC19", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLK", "DOLPP1", "DPAGT1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DSTN", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "EMC1", "EMC10", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC5", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FASTKD5", "FBL", "FBXO21", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS3", "GINS4", "GIPC1", "GJA1", "GLA", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH1", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IER3IP1", "IFT27", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "ING5", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "IRS4", "ISG20L2", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JAK1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDAH", "LDHA", "LDHB", "LDLR", "LDLRAP1", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "MACF1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MALT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARS", "MARS2", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED14", "MED16", "MED18", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METTL1", "METTL3", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MGAT2", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRC2", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFMT", "MTFP1", "MTG1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR14", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MXRA7", "MYBBP1A", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "ND5", "NDC1", "NDC80", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFA", "NELFCD", "NEMF", "NENF", "NF1", "NFATC2IP", "NFRKB", "NFS1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAFAH2", "PAICS", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCF11", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMVK", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMK", "PON2", "POP1", "POR", "PPA1", "PPAN", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB10", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB24", "RAB29", "RAB2A", "RAB31", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB8B", "RAB9A", "RABAC1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RAI14", "RALA", "RALB", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP7", "RBFA", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM47", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REEP6", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFTN1", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF2", "RNF25", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARAF", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP3", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDAD1", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERAC1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A4", "SLC30A5", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP47", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX19", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR4", "SSRP1", "ST3GAL4", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STAU1", "STEAP3", "STIM1", "STIM2", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STRN4", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TAF15", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TDRKH", "TEAD1", "TECR", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX2", "TEX264", "TFAM", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THEM6", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM10B", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKT", "TLN1", "TM9SF3", "TM9SF4", "TMA16", "TMBIM6", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM104", "TMEM109", "TMEM126A", "TMEM14C", "TMEM160", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53I11", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRIM13", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIO", "TRIP10", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP3", "TUBGCP4", "TUBGCP5", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFM1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS13C", "VPS13D", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WBP11", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF131", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZNF830", "ZPR1", "ZRANB2", "ZW10", "ZYG11B", "ZYX", "ZZEF1"], "leading_proteins": ["ABCB1", "ABCB7", "ABCD4", "ABHD12", "ACAD11", "ACBD5", "ACOX1", "ACOX3", "ACP2", "ACP6", "ADK", "ADPGK", "AFG3L2", "AGK", "AKT2", "ALDH3A2", "ALG1", "ALG11", "ALG12", "AMFR", "ANKLE2", "ANO6", "APOO", "ARL10", "ARL6IP1", "ARMC10", "ASAH1", "ASNA1", "ATAD1", "ATAD3A", "ATG9A", "ATL2", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATXN10", "AUP1", "B4GALT1", "B4GAT1", "BCAP31", "BCL2L13", "BCS1L", "BNIP1", "BSG", "C14orf2", "C16orf58", "C19orf70", "C5orf15", "CAMK1", "CANT1", "CANX", "CCDC47", "CD47", "CDIPT", "CDK4", "CDKAL1", "CDS2", "CENPK", "CEPT1", "CERS1", "CERS2", "CHST14", "CKAP4", "CLCC1", "CLCN3", "CLCN7", "CLN5", "CLN6", "CLPTM1", "CLPTM1L", "COA3", "COMT", "COMTD1", "COQ8A", "COX11", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "CPOX", "CPT1A", "CPT2", "CRTAP", "CTSA", "CTSC", "CYB5B", "CYB5R1", "CYP20A1", "CYP51A1", "DAGLB", "DCAKD", "DERL2", "DHCR24", "DHCR7", "DHDDS", "DIABLO", "DNA2", "DNAJC1", "DNAJC11", "DNAJC16", "DOLPP1", "DPAGT1", "DYM", "ECE1", "EFCAB14", "EFL1", "EI24", "EIF2B5", "EMC7", "EMD", "ENDOD1", "EPDR1", "EPHX1", "ERAP1", "ERAP2", "ERGIC1", "ERGIC2", "ERGIC3", "ERMP1", "ERO1A", "EWSR1", "EXT2", "FAF2", "FAM162A", "FAM177A1", "FAM213A", "FAM3C", "FAM8A1", "FARSB", "FDFT1", "FDPS", "FECH", "FKBP14", "FKBP7", "FNTA", "FNTB", "FOXRED1", "FUCA2", "FUS", "GALNT1", "GALNT4", "GBA", "GDAP1", "GGCX", "GHITM", "GJA1", "GLG1", "GLUD1", "GM2A", "GNPAT", "GNS", "GOLGA5", "GOLGB1", "GOLIM4", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GPAA1", "GPAM", "GPAT4", "GPR107", "GPR108", "GPX8", "GSK3B", "GSTO1", "GTF2E2", "GUSB", "HACD2", "HACD3", "HADH", "HADHA", "HCCS", "HIGD1A", "HK2", "HLA-A", "HMGCR", "HMOX1", "HMOX2", "HNRNPDL", "HS2ST1", "HSD17B11", "HSD17B12", "HSDL1", "ICMT", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "ITM2B", "ITM2C", "ITPRIP", "JAGN1", "JAK1", "KDELR1", "KDELR3", "KDSR", "KIAA0100", "KIAA2013", "KLC2", "LAMP1", "LAMP2", "LBR", "LDAH", "LEMD2", "LETM1", "LMAN1", "LMF2", "LNPEP", "LNPK", "LPCAT1", "LPGAT1", "LRRC59", "LTA4H", "LYSMD3", "MAGT1", "MAN2A1", "MAVS", "MBOAT7", "MCL1", "METTL7B", "MFN1", "MFSD3", "MGAT2", "MGEA5", "MGST2", "MIA2", "MIA3", "MICU1", "MIF", "MIGA1", "MMGT1", "MPC2", "MPDU1", "MPV17", "MPV17L2", "MRC2", "MSI2", "MSMO1", "MSTO1", "MTAP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTX1", "MUL1", "MXRA7", "NAMPT", "NCEH1", "NCLN", "ND1", "ND5", "NDC1", "NDUFA11", "NDUFA13", "NDUFAF1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS2", "NEDD4L", "NEFL", "NNT", "NPC1", "NRM", "NT5C2", "NUCB1", "NUCB2", "NUP160", "NUP35", "NUP54", "NUPL2", "OCIAD1", "OPA1", "OPA3", "OSBPL2", "OSBPL8", "OXA1L", "P3H1", "P4HA2", "PANX1", "PARL", "PCYOX1", "PCYOX1L", "PDCD6", "PDK1", "PEX14", "PEX19", "PEX3", "PGRMC1", "PGRMC2", "PIGG", "PIGK", "PIGU", "PISD", "PKMYT1", "PLD3", "PLD6", "PMPCA", "POMK", "PON2", "POR", "PPT1", "PRAF2", "PREPL", "PSAP", "PSMB2", "PSMB5", "PTDSS2", "PTGES2", "PTPMT1", "PUF60", "PVR", "PXMP2", "RDH11", "RDH13", "RDH14", "REEP2", "REEP3", "REEP4", "REEP5", "REEP6", "RER1", "RETREG3", "RFT1", "RHBDD2", "RMDN3", "RMND1", "RPS6KA3", "RTN1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "SACM1L", "SAMM50", "SARAF", "SC5D", "SCAMP3", "SCAP", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCO1", "SCO2", "SDF4", "SDHB", "SEC11A", "SEC61A1", "SEC62", "SEC63", "SEL1L", "SERAC1", "SET", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3GLB1", "SIGMAR1", "SIRT2", "SLC19A1", "SLC25A10", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A2", "SLC30A5", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC44A1", "SLC4A7", "SLC6A15", "SLC7A1", "SMN1*", "SMPD4", "SNX19", "SOAT1", "SPART", "SPCS2", "SPNS1", "SPTBN2", "SPTLC1", "SQLE", "SRPRB", "SSR1", "SSR4", "ST3GAL4", "STARD7", "STEAP3", "STIM1", "STT3A", "STT3B", 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--- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Endoplasmic reticulum 82 218 5.479144162662743 4.27388039599649e-08 55.37621359223301 196.57766990291265 1.2201083743235763 0.4903523338807414 18.868778270733547 13.264167600850914 1.8573715045605257 0.4308007257692164 1.248087282297544e-27 0.0002296910879912 9.270999213619348e-07 1.4293008255197746e-17 4.1781200762652114e-35 +Golgi apparatus 72 188 4.165794224922374 3.1027047476150926e-05 46.45873786407767 176.03155339805826 1.3643789213018729 0.3972771337532677 14.511319530749702 26.453870355965975 1.6568954592349954 0.4161874156663988 0.0040809990602922 0.0937351458200969 4.061235774608551e-05 0.0005509279209522 7.565345185772481e-05 +Mitochondria 129 433 3.277687640109537 0.0010466114240381 110.1747572815534 400.5485436893204 0.4320244196044261 0.5794127039570083 42.49664228528663 36.15232166758906 2.0400795827803786 0.4211568684384254 1.3664369254302195e-16 0.0001620433339141 3.296038785257671e-07 1.2470244606230709e-12 3.9173176050855763e-20 +Nuclear membrane 23 64 2.6670305729448605 0.0076524710167273 16.817961165048544 62.713592233009706 0.5402747034161678 0.5293388535672136 7.339768502370818 5.865441797870943 1.2287110387783358 0.3803813474041967 0.0100527736329381 0.0566899593979067 0.2500826326170608 0.2763445956493622 0.006865222506977 +Vesicles 76 305 2.362721981999767 0.018141273256272 63.69174757281554 303.19174757281553 0.3021616120018026 0.6308308858815788 16.21576692438533 35.60761931464484 1.2670437076534344 0.3993041904676221 0.0217384295372565 0.5176453012227896 0.7112390798748155 0.0636256332984145 0.0999556118507318 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cc9187eb213d9c1323aaf6e6ab7feebb9169f2fa --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3198, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 148.12121212121212 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6a779e9a32255b37d8251be9c66b448748175d1c --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C092/C092_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..eb94de8cda2f312cd38997dbf0b87a7f7e38c38b --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,12 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endoplasmic reticulum 0.547208075894489 5.479144162662743 4.27388039599649e-08 1.4103795662646354e-06 4.7012684357061393e-07 218 O43169,Q9NQC3,P43307,O95197,O96005,Q15800,Q8N0U8,Q96G23,P51648,Q96A57,Q9NZ01,O95674,Q4ZIN3,Q86UE4,Q9P2W9,P21964,Q9Y680,O00264,O00767,Q8NHH9,Q8NF37,Q9BRK0,O95470,Q9H6H4,Q96A33,Q9P035,P84157,O75845,Q96PC5,Q9BT22,Q16799,Q96S66,Q96KC8,Q14257,P37268,Q99735,Q96BY9,Q9NR31,P27544,Q12981,Q6UW68,Q9H3N1,Q9NWW5,P50402,O43292,Q9BV10,Q96AG4,Q15041,Q00765,P51572,Q8IV08,Q16850,Q96KA5,Q92791,Q8TCJ2,P62820,Q86XL3,Q9GZP9,Q03519,Q15043,Q96CN7,O14681,P49257,O15260,O60831,P51571,Q6PIU2,Q70UQ0,Q96CS3,P35610,O15269,Q96HR9,Q9UM00,Q86Y07,Q9H0U4,Q99442,O43852,P61619,Q9UKV5,O15460,Q9UBM7,Q9UGP8 82 +Golgi apparatus 0.4634951985613205 4.165794224922374 3.1027047476150926e-05 0.0010233844358281 0.0002559731416782 188 P67812,Q93063,Q9NTJ5,P24390,Q8N4A0,Q10469,O60637,Q8TBA6,Q9HB40,Q99640,O60499,Q8NC54,Q96RQ1,Q13190,Q9BSL1,Q96JB2,Q9BRK5,O14683,Q8IXU6,Q6P179,P50897,Q7RTS9,Q9BSR8,Q9UBU6,O43760,Q96GQ5,P09601,Q9BXB4,Q9H3P7,Q8IYS2,Q9HD45,Q9H4A6,Q92520,Q5T6V5,Q14789,P80303,P98194,Q9H0U4,P49755,O75071,Q86VU5,O14653,Q5VW38,Q8NCH0,Q8WVQ1,Q16706,Q9NWM8,Q9UKV5,Q9UG56,O00461,Q8N4Q0,Q15043,O15258,Q02818,P04439,Q8TAD4,Q9H2V7,Q9HD26,Q93050,Q96J42,Q9NPR9,Q8NE00,O14681,P15291,O95070,A1L0T0,Q9NX62,O15260,P55327,Q9Y287,Q6NTF9,Q92896 72 +Mitochondria 0.371383506143425 3.277687640109537 0.0010466114240381 0.0339660144304424 0.005652351059263 433 Q9Y2R0,O75431,Q99595,Q9HCL2,Q96A26,Q8WVV9,Q9UHQ9,Q8WUK0,O14949,P45880,Q8N4H5,O95139,Q68CZ6,Q86Y39,Q7Z7H8,O75352,Q9BUR5,Q8WWI5,Q5XKP0,Q9UDX5,Q7Z434,Q9NS69,Q9Y277,Q3ZCQ8,P36551,Q86VD7,Q9NQ50,Q9H2D1,Q9Y4W6,Q9NWU5,Q9H936,Q9UBX3,O75208,O75964,Q5TC12,Q92543,Q969V5,P13073,O75027,P57105,Q15070,Q13505,Q69YU5,Q9H0B6,O14925,P21912,P53701,Q10713,Q9H4I3,Q9Y6C9,Q8NBM8,O95298,Q7KZN9,Q9BT17,Q9NX40,Q9Y6M9,Q9HC21,Q96C01,Q7LGA3,Q8NBN7,Q9Y241,Q6P4A7,Q9P0J0,P62072,Q70HW3,Q9H3K2,Q9H300,Q9NVH1,Q3SXM5,Q8N2F6,Q9BXK5,P56378,P52789,Q6DKK2,Q8WWC4,Q07820,Q9Y6N5,O43292,Q9H7Z7,P40939,Q13423,Q96IX5,Q6UXV4,P12235,P24539,Q16836,P56385,P23786,Q9NVI7,Q6NUK1,Q9Y394,Q9NQH7,O96008,P56134,Q9NQZ5,O43615,P51530,Q16880,Q9NX14,Q8IWA4,Q96TC7,Q96CU9,Q96NB2,P12236,Q5T9A4,Q9BPX6,Q9BUB7,Q9Y512,O95202,O75648,Q16891,Q8NBU5,Q9NPL8,O60313,Q8TB36,Q9Y375,Q99623,Q16540,P00367,Q8NI60,Q9NWS8,Q8NAN2,P05141,O75306,O43819,Q53H12,P50416,O15498,Q9NR28 129 +Nuclear membrane 0.4805403237585547 2.6670305729448605 0.0076524710167273 0.2239223866673837 0.0280590603946671 64 P67812,P50402,Q8NFH5,Q9BVC6,Q96SK2,Q14739,Q9H1E5,Q9NXE4,Q5SNT2,Q9H8M7,O14735,Q96G23,Q9BTX1,O94919,Q86VR2,Q9UH99,O94901,P11802,P56134,Q9BW91,Q8IXM6,Q6UW68,O15260 23 +Vesicles 0.3457007388117663 2.362721981999767 0.018141273256272 0.4534660464440156 0.049888501454748 305 Q9Y3E0,O60831,Q00169,P24390,Q9Y487,O15020,Q9UNK0,O60499,Q96RQ1,Q6IQ22,Q96SK2,Q08722,P15151,P50897,Q96AA3,Q9BSR8,P48739,Q9Y2G8,Q9NRY5,Q96GQ5,P51790,P13473,P30519,Q9HD20,Q96ES6,Q86YN1,Q6P4A7,O15118,P17302,Q9HD45,Q8NBX0,Q9H4A6,P17900,Q92791,Q3SXM5,Q9GZU8,O14966,Q8IWB1,Q9H2J7,Q14534,O75153,P35613,Q15363,Q8N128,Q8N4Q0,Q8IXH7,O14828,O15460,P52789,Q6UX53,Q32P28,Q9H2V7,Q7Z3C6,Q93050,P31751,Q9NPR9,Q8NBJ7,Q96CN7,P53611,P10619,Q8TB61,Q86VX2,O95070,P21964,Q969X5,P07602,P49257,P16435,A1L0T0,P08236,Q53H12,Q9Y287,Q9NWW5,Q8WTV0,Q8N5M9,O43399 76 +Lipid droplets 0.6804754084867104 1.9150314218825797 0.0554884964993123 0.848001498628335 0.1307943131769504 9 Q96CS3,Q8NF37,Q01105,Q969V3 4 +Peroxisomes 0.5583451472096665 1.8550824955201584 0.0635844470431576 0.8855898898399125 0.1398857834949469 16 P40855,P28288,O43808,O75381,O15254,Q15067,P56589,Q5T8D3,Q8WVX9 9 +Rods & Rings 0.6199537520495106 1.112457895899413 0.2659413235892578 0.9999629220582552 0.3785858512074975 6 Q96BY9 1 +Intermediate filaments 0.2960565608339639 0.4017802170789134 0.6878457826186088 1.0 0.7566303608804698 35 Q99442,Q9UJX5,O75718,Q16352,P07196,Q86YN1,P08670,O60884,Q3SXM5 9 +Centrosome 0.2616487002531827 0.1069311745287265 0.9148435812760564 1.0 0.944571558558416 67 Q69YU5,P49356,O43292,Q9BRR6,P28074,Q96RT8,P52789 7 +Lysosomes 0.3265993466078595 0.1055389335206471 0.9159481779960396 1.0 0.944571558558416 11 O15400,Q8WTV0 2 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2484213246d86ecaf4ee253b347bd90897a295d5 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAGAB", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ADA", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADPRHL2", "ADRM1", "ADSL", "ADSS", "AFAP1", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AK6", "AKAP1", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALG5", "ALKBH5", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APEH", "APEX1", "API5", "APMAP", "APOO", "APOOL", "APRT", "AQR", "ARCN1", "ARFGAP1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL15", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC5", "ARVCF", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG4B", "ATG9A", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "AURKA", "B4GALT1", "BABAM1", "BABAM2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1B", "BCAP31", "BCAS2", "BCCIP", "BCKDHB", "BCL2L12", "BCL2L13", "BCLAF1", "BEND3", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BROX", "BSG", "BTAF1", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C19orf70", "C1QBP", "C1orf35", "C2CD2", "C2CD5", "C2orf49", "C5orf15", "C8orf33", "C9orf64", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CASP2", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCDC124", "CCDC127", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCDC97", "CCNB1", "CCNB2", "CCNK", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC20", "CDC27", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPH", "CENPI", "CENPU", "CENPV", "CEP170", "CEP290", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHST14", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN6", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT2", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG8", "COIL", "COL4A3BP", "COLEC12", "COLGALT1", "COMMD1", "COMMD7", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS8", "COQ8A", "COQ8B", "COQ9", "CORO1B", "COTL1", "COX15", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRKL", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAD1", "DAG1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEGS1", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DGCR8", "DHCR7", "DHDDS", "DHFR", "DHODH", "DHPS", "DHRS13", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAP1", "DNA2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DOLK", "DOLPP1", "DPH2", "DPH5", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL4", "DPYSL5", "DRG1", "DRG2", "DSG2", "DSP", "DST", "DTNA", "DTYMK", "DUS2", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX2", "EPPK1", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESYT1", "ESYT2", "ETFA", "ETFB", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC7", "EXOG", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EYA4", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM208A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM98A", "FAM98B", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXO21", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNBP4", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GHITM", "GIGYF2", "GINS3", "GINS4", "GIPC1", "GJA1", "GLB1", "GLDC", "GLE1", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNE", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR2", "GOT1", "GPAA1", "GPAM", "GPATCH1", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRIPAP1", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2E2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS1", "HAUS3", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HECTD1", "HELLS", "HEXA", "HGH1", "HGS", "HIBCH", "HIGD1A", "HINT2", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTRA2", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "ICE1", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IER3IP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INTS1", "INTS10", "INTS11", "INTS13", "INTS14", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRF2BPL", "ISG20L2", "ISOC1", "IST1", "ISY1", "ISYNA1", "ITGB1", "ITM2B", "ITPA", "ITPRIP", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC1", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDHA", "LDHB", "LDLRAP1", "LEMD2", "LEMD3", "LENG8", "LETM1", "LIG1", "LIG3", "LIMA1", "LIPA", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LMO7", "LNPK", "LONP1", "LPCAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8C", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "MACF1", "MAGED2", "MAIP1", "MAK16", "MALT1", "MAN1A1", "MAN2A1", "MAN2B1", "MANF", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED14", "MED16", "MED18", "MED21", "MED23", "MED4", "MEPCE", "MESD", "METTL1", "METTL7B", "METTL9", "MFN1", "MFN2", "MFSD10", "MFSD3", "MGAT2", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MMAB", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL20", "MRPL21", "MRPL22", "MRPL23", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTA3", "MTAP", "MTBP", "MTCH2", "MTDH", "MTFMT", "MTFP1", "MTG1", "MTHFD1L", "MTHFD2", "MTHFS", "MTOR", "MTPAP", "MTPN", "MTR", "MTSS1L", "MTX1", "MTX2", "MUL1", "MUT", "MXRA7", "MYBBP1A", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NARS2", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA12", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFC2", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP2", "NECTIN2", "NEFL", "NEFM", "NELFA", "NELFCD", "NEMF", "NF1", "NFATC2IP", "NFRKB", "NFS1", "NHLRC2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NRM", "NSA2", "NSD1", "NSD2", "NSDHL", "NSF", "NSL1", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD3", "NUDT1", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "OSBP", "OSBPL11", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTULIN", "OXA1L", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PATL1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCF11", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1L", "PDAP1", "PDCD11", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDXK", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PES1", "PEX11B", "PEX14", "PEX19", "PEX3", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PIBF1", "PICALM", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PINX1", "PIP4K2A", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLD3", "POLDIP2", "POLDIP3", "POLE", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POP1", "POR", "PPA1", "PPAT", "PPCDC", "PPHLN1", "PPIB", "PPID", "PPIF", "PPIG", "PPIL1", "PPIL4", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6R2", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID1", "PRELID3B", "PREP", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF39", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PSPH", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PVR", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT2", "RAB12", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB24", "RAB29", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAD51C", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RARS", "RARS2", "RAVER1", "RB1", "RBBP5", "RBBP7", "RBFA", "RBL1", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM47", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP4", "REEP5", "REEP6", "RER1", "RETREG3", "RETSAT", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIPK1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNF2", "RNF25", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPP38", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS19BP1", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCA", "RTCB", "RTFDC1", "RTN1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP130", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARAF", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SDAD1", "SDE2", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD3", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC30A5", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A14", "SLC3A2", "SLC44A1", "SLC4A2", "SLC4A7", "SLC6A15", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLMAP", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP47", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX19", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOAT1", "SOD2", "SON", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPC25", "SPCS2", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQOR", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STARD7", "STAT1", "STAT3", "STAU1", "STEAP3", "STIM1", "STIP1", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STRN4", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT3H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TDRKH", "TEAD1", "TECR", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX2", "TEX264", "TFAM", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THEM6", "THOC1", "THOC2", "THOC3", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM10", "TIMM13", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM104", "TMEM109", "TMEM126A", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM70", "TMOD3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53I11", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIO", "TRIP10", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TUBGCP2", "TUBGCP4", "TUBGCP5", "TUFM", "TWF1", "TWF2", "TWISTNB", "TXLNA", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC45A", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCRC1", "UQCRC2", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP24", "USP34", "USP39", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VIM", "VIRMA", "VKORC1L1", "VPS13C", "VPS13D", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WBP11", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR74", "WDR77", "WDR82", "WIPI2", "WIZ", "WRNIP1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YEATS4", "YIF1A", "YIPF4", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMYM2", "ZMYND8", "ZNF131", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF687", "ZNF830", "ZPR1", "ZRANB2", "ZW10", "ZYG11B", "ZYX", "ZZEF1"], "leading_proteins": ["ABCB7", "ABCD3", "ACBD3", "ACBD5", "ACOX1", "ACOX3", "ADPGK", "AFG3L2", "AGK", "AKT2", "ALDH3A2", "ALG1", "ALG12", "AMFR", "ANAPC4", "ANKLE2", "APOO", "APOOL", "ARL6IP1", "ARMC10", "ATAD1", "ATAD3A", "ATAD3B", "ATG9A", "ATL2", "ATP13A1", "ATP2C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATPAF1", "B4GALT1", "BCAP31", "BCL2L13", "BNIP1", "BSG", "C12orf73", "C14orf2", "C16orf58", "C19orf70", "C5orf15", "C9orf64", "CALU", "CANT1", "CCDC47", "CD47", "CDIPT", "CDK4", "CDS2", "CERS1", "CERS2", "CHST14", "CLCC1", "CLCN3", "CLN6", "CLPTM1", "CLPTM1L", "CLUH", "COA3", "COG3", "COMMD7", "COMT", "COMTD1", "COQ8A", "COQ9", "COX15", "COX4I1", "CPOX", "CPT1A", "CPT2", "CRTAP", "CTSA", "CYB5B", "CYB5R1", "CYP51A1", "DERL2", "DHCR7", "DHRS7", "DIABLO", "DNA2", "DNAJA2", "DNAJC1", "DNAJC11", "DNAJC16", "DOLPP1", "DYM", "EFCAB14", "EI24", "EMD", "ENDOD1", "ERAP2", "ERGIC1", "ERGIC2", "EXT2", "FAF2", "FAM114A2", "FAM136A", "FAM162A", "FAM177A1", "FAM192A", "FAM3C", "FAM8A1", "FAR1", "FDFT1", "FKBP14", "FKBP7", "FNTB", "FOXRED1", "GALNT4", "GDAP1", "GHITM", "GJA1", "GLG1", "GLUD1", "GM2A", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GOSR2", "GPAA1", "GPAM", "GPR107", "GPR108", "GUSB", "HACD3", "HADH", "HADHA", "HAUS3", "HCCS", "HIGD1A", "HK2", "HLA-A", "HMOX1", "HMOX2", "HNRNPLL", "HS2ST1", "HSDL1", "IKBIP", "ILVBL", "IMMT", "IMPAD1", "INA", "ISOC1", "ITM2B", "ITPRIP", "JAGN1", "KDELR1", "KIAA2013", "KLC2", "LAMP2", "LBR", "LETM1", "LMAN1", "LPCAT1", "LRRC59", "MAIP1", "MAN2A1", "MAVS", "MCL1", "METTL7B", "MFN1", "MFSD3", "MGAT2", "MGST2", "MIA2", "MICU1", "MIGA1", "MINDY3", "MPDU1", "MRPL10", "MRPL22", "MRPL23", "MRPL40", "MSMO1", "MTCH2", "MTDH", "MTFP1", "MTG1", "MTX1", "MTX2", "MUL1", "MXRA7", "NCEH1", "NCLN", "NDC1", "NDUFA11", "NDUFA13", "NDUFAF1", "NDUFB11", "NDUFB6", "NDUFB9", "NDUFC2", "NDUFS2", "NEFL", "NELFCD", "NNT", "NPC1", "NRM", "NUCB1", "NUCB2", "NUDT9", "NUP35", "OCIAD1", "OPA1", "OSBPL11", "OXA1L", "P3H1", "P3H4", "P4HA2", "PARL", "PCYOX1L", "PEX14", "PEX19", "PEX3", "PGRMC1", "PHB2", "PISD", "PITPNA", "PITPNB", "PKMYT1", "PLD3", "PMPCA", "POR", "PPT1", "PRAF2", "PSAP", "PSMB5", "PTGES2", "PTPMT1", "PVR", "RAB12", "RAB1A", "RAB1B", "RAB29", "RABGGTB", "RCN2", "RDH13", "REEP2", "REEP4", "REEP5", "REEP6", "RER1", "RETREG3", "RFT1", "RHBDD2", "RMDN3", "RMND1", "RTN1", "RTN3", "RTN4", "SACM1L", "SAMM50", "SAR1A", "SARAF", "SC5D", "SCAMP3", "SCARB1", "SCCPDH", "SCD", "SCO2", "SCPEP1", "SDF4", "SDHB", "SEC11A", "SEC61A1", "SEC62", "SEC63", "SET", "SFXN2", "SFXN4", "SGPL1", "SLC25A10", "SLC25A17", "SLC25A19", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC30A5", "SLC35B2", "SLC35F2", "SLC39A14", "SLC44A1", "SLC6A15", "SMPD4", "SNX19", "SOAT1", "SPNS1", "SPTBN2", "SPTLC1", "SQLE", "SQOR", "SSR1", "SSR4", "STARD7", "STT3B", "STX10", "STX18", "STX5", "STX7", "STX8", "SUMF2", "SUN1", "SUN2", "SURF4", "SYNGR2", "SYNJ2BP", "TAP2", "TECR", "TIMM10", "TIMM17A", "TIMM23", "TIMM44", "TIMM50", "TIMMDC1", "TM9SF3", "TMCO1", "TMED10", "TMED2", "TMEM104", "TMEM109", "TMEM201", "TMEM205", "TMEM209", "TMEM230", "TMEM259", "TMEM70", "TMX1", "TMX4", "TOMM22", "TOMM40", "TOMM5", "TP53I11", "TPD52", "TPD52L2", "TRABD", "TRMU", "TSPAN3", "TTC19", "TUBGCP5", "TXNDC15", "UBAC1", "UGT8", "UQCRQ", "USMG5", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VRK2", "XPNPEP3", "YIF1A", "YIPF4", "YKT6", "ZADH2"]} \ No newline at end of file