| Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size |
| Electron transport chain oxphos system in mitochondria 0.6504049617280272 3.968868880141964 7.221460189388296e-05 0.0424741327674457 0.0035197079792642 56 P09669,P21912,O14949,Q9UI09,P03886,O75964,P24539,P56385,Q9Y6M9,P13073,O14548,P05141,P22695,P00846,P12236,P00403,Q9UDW1,O43676,O95169,P20674,O75880,O96000,P14927,O75306,P12235,O95168,O95298,Q9Y6N1,O95139,Q7KZN9,P56134,P03915 32 |
| Cholesterol metabolism with bloch and kandutschrussell pathways 0.7492444909712408 3.358927386089178 0.0007824562472855 0.3752728459588201 0.0126522377130391 23 P04035,Q14739,Q15392,Q15800,O95864,O60488,Q16850,O75845,O95573,P37268,P33121,Q9UBM7,Q14534,P35610,O00767 15 |
| Nonalcoholic fatty liver disease 0.5919726718791573 3.313169039830987 0.0009224520919848 0.4257265287997234 0.0126522377130391 49 P09669,P21912,O14949,Q9UI09,Q86Y39,Q9Y6M9,P13073,Q9NX14,O14548,Q9P0J0,P22695,P49841,P00403,Q9UDW1,O43676,O95169,P20674,O96000,P14927,O75306,O95168,O95298,P08574 23 |
| Vitamin d metabolism 0.915179968701095 3.294452155198984 0.0009861373084103 0.4473116180416779 0.0126522377130391 3 P38435,P04062 2 |
| Nuclear receptors in lipid metabolism and toxicity 0.8623279098873584 3.2604382261150096 0.001112401957229 0.4877413995472855 0.0136439505366258 2 P08183 1 |
| Zinc homeostasis 0.7994367959950139 2.9520254146353495 0.0031569694599653 0.8504822080791206 0.0279947147957347 2 Q8TAD4 1 |
| Irinotecan pathway 0.7984981226533143 2.9473299246669424 0.0032053101809434 0.8547770850986453 0.0279947147957347 2 O15118 1 |
| Hostpathogen interaction of human coronaviruses apoptosis 0.7794117647059022 2.851246493235988 0.0043548195976692 0.9274124598860244 0.0331297035215176 2 Q07820 1 |
| Cardiac progenitor differentiation 0.779411764705884 2.851246493235907 0.0043548195976703 0.9274124598860728 0.0331297035215176 2 P49841 1 |
| Mitochondrial complex i assembly model oxphos system 0.5838864037761612 2.7840712038415867 0.0053681248157138 0.960637180160678 0.0398301606696789 32 Q9BUB7,O95168,O95298,Q8N183,Q9Y6M9,Q9NX14,Q9UI09,P03886,O43676,Q9Y375,O95169,Q9P0J0,O96000,Q9NPL8,P03915,O75306 16 |
| Pkcgamma calcium signaling pathway in ataxia 0.7593867334167722 2.749172068821513 0.0059746013109927 0.9727173664046868 0.0422439457400777 2 P23634 1 |
| Sarscov2 and covid19 pathway 0.798307007198156 2.741112995100873 0.0061231446082703 0.9750610073292432 0.0427908129019823 3 P35610 1 |
| Triacylglyceride synthesis 0.8655073274277454 2.7017397575700546 0.0068977728530625 0.9843912737332304 0.0445759299429098 5 Q99943,O15228,Q9HCL2 3 |
| Arachidonate epoxygenase epoxide hydrolase 0.744055068836055 2.6701284036932194 0.0075822245339878 0.9896862833303722 0.0463095783872382 2 P20674 1 |
| Oxidative phosphorylation 0.5536104431928642 2.668418412779256 0.0076209285150921 0.989925218132292 0.0463095783872382 34 P00846,P56385,O95168,O95298,Q9Y6M9,Q86Y39,P03886,O95169,O75964,O96000,P56134,P24539,P03915,O75306 14 |
| Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.8179069815871832 2.639666772122153 0.0082987580797551 0.9933181746335318 0.0493817188706219 4 P09601 1 |
| Omega3 omega6 fatty acid synthesis 0.8818922305764425 2.619604651227287 0.008803175749694 0.995078459671916 0.0518696924075108 6 O95864,O95573,P33121,O15254,O60488 5 |
| Cholesterol biosynthesis with skeletal dysplasias 0.8787593984962425 2.605669136099245 0.0091694989203499 0.9960588799715984 0.0528087755125678 6 Q14739,Q15392,Q16850,O75845,Q9UBM7 5 |
| Mitochondrial complex iv assembly 0.7820004072689251 2.604405972220954 0.0092033670203994 0.9961390181943486 0.0528087755125678 13 Q9Y2R0,Q9Y6N1,O43819,P13073,P09669,P00403,Q8N8Q8,Q7KZN9,P20674,P15954,Q9Y241 11 |
| Ferroptosis 0.6291492134747184 2.5828116171579834 0.0097998816952871 0.9973115169439852 0.0551824570688312 23 P04035,Q9Y277,Q96QD8,P09601,O95573,P37268,P33121,P16435,P45880,O60488 10 |
| Fatty acid transporters 0.805358781631776 2.57985731340368 0.0098841145616548 0.9974455167087444 0.0551824570688312 4 P33121,O60488 2 |
| Sarscov2 b117 variant antagonises innate immune activation 0.7259073842302828 2.5755481827606252 0.0100081328128163 0.9976307671320958 0.0551824570688312 2 O94826 1 |
| Vitamin b12 disorders 0.760091309405692 2.5515260834613107 0.0107252295713546 0.99846723014083 0.0566353344715299 3 P22033 1 |
| Sphingolipid metabolism integrated pathway 0.8294488728912055 2.5251421324732615 0.0115651504357572 0.9990800219089933 0.0589038594227974 10 Q13510,O95470,Q16880,Q96G23,O15269,Q06136 6 |
| Sphingolipid metabolism overview 0.8294488728912055 2.5251421324732615 0.0115651504357572 0.9990800219089933 0.0589038594227974 10 Q13510,O95470,Q16880,Q96G23,O15269,Q06136 6 |
| Glycerolipids and glycerophospholipids 0.8458240178250406 2.490669086904786 0.012750281053828 0.9995526594349172 0.0633299083747987 7 Q86UL3,Q9UG56,Q9HCL2,Q9BVG9 4 |
| Metabolism of spingolipids in er and golgi apparatus 0.8486842105263187 2.4706678758997236 0.013486100369302 0.999714222244775 0.0658954985524435 6 O95470,Q10472,P15291,Q16880,Q06136 5 |
| Ppar signaling pathway 0.7123028562698718 2.467022460334857 0.0136241811503845 0.999737280341199 0.0660050668088917 15 P22307,O60488,O95864,O14975,O95573,P33121,O15254,Q15067,O00767 9 |
| Omega9 fatty acid synthesis 0.8472773919935239 2.4642984374087127 0.0137281752930307 0.9997534116300524 0.0660050668088917 6 O60488,O95573,P33121,O00767 4 |
| Autosomal recessive osteopetrosis pathways 0.6983729662077676 2.429902253299801 0.0151028953317615 0.9998933631504032 0.0714711818455803 2 P51149 1 |
| Oxidation by cytochrome p450 0.8367003557596333 2.4162530779101155 0.0156811579724878 0.9999250770410668 0.0736279370426966 6 Q16850,O43169,P16435,Q6UW02 4 |
| Proteoglycan biosynthesis 0.8293687573576113 2.382786378724334 0.0171821617667353 0.9999700572800282 0.0788617229905994 6 Q9NX62,Q8NCH0 2 |
| Sphingolipid pathway 0.7763939586770824 2.362934739551926 0.0181308620475304 0.9999832421103946 0.0813182693325806 11 Q13510,O95470,Q16880,Q16739,Q96G23,O15269,P04062,Q06136 8 |
| Glycerophospholipid biosynthetic pathway 0.793991057632396 2.3542467119724377 0.0185602879082422 0.9999871163248067 0.0820200958298059 10 O95674,Q86UL3,Q9HCL2,Q9Y6K0,O00116,O15228,O14735 7 |
| Overlap between signal transduction pathways contributing to lmna laminopathies 0.6883111916410826 2.330091425909812 0.0198013195020152 0.9999939774246478 0.0850042358622226 15 P49354,P49841,P42167,O75844,P11802,P50402,O60725 7 |
| Kennedy pathway from sphingolipids 0.8154664276235009 2.318956849812441 0.0203973761264519 0.999995821563861 0.0860107653832704 6 O95470,Q9UG56,Q9BVG9 3 |
| Riboflavin and coq disorders 0.7822922291829267 2.3139552840916684 0.020670175090796 0.9999964655852256 0.0862692724275585 5 O75208,Q16134 2 |
| Regulation of apoptosis by parathyroid hormonerelated protein 0.7813042893563084 2.3092407296082813 0.0209302265934998 0.9999969869982492 0.0867521805702994 5 Q07820,Q9BXK5 2 |
| Glycosylation and related congenital defects 0.7237275335464376 2.296129004463294 0.021668506349014 0.9999980852743412 0.0885902878622956 13 Q2TAA5,O75340,Q9H0U3,O75352,Q9BT22,Q9H3H5,Q10469,Q9BV10 8 |
| Mitochondrial long chain fatty acid betaoxidation 0.6973460788794285 2.262810315468233 0.0236473847515219 0.9999994329478108 0.0938498421631853 14 O60488,P40939,O95573,P33121,P49748,P22307 6 |
| Pi3kaktmtor signaling pathway and therapeutic opportunities 0.7384657380895154 2.253456357793169 0.0242303894946243 0.9999996039771486 0.0945614551056442 4 Q15382,P49841 2 |
| Mapk pathway in congenital thyroid cancer 0.6551939924906054 2.1961987881750025 0.0280777180828624 0.999999963140048 0.1036752267113706 2 Q02750 1 |
| Ethanol metabolism production of ros by cyp2e1 0.6551939924906054 2.1961987881750025 0.0280777180828624 0.999999963140048 0.1036752267113706 2 Q02750 1 |
| Metapathway biotransformation phase i and ii 0.5723748759773236 2.189968484909381 0.0285265224923818 0.9999999720745664 0.1039056970783121 23 O14880,Q16850,P07099,P21964,Q8NCH0,Q99735,Q6UW02 7 |
| Mitochondrial complex iii assembly 0.752422134215631 2.1494414096052767 0.0315994258693344 0.999999995840147 0.1106879527288526 10 Q9BRT2,P22695,O14949,P08574,Q9UDW1,P14927,Q6DKK2 7 |
| Cholesterol biosynthesis pathway 0.6933238498838092 2.130798504682811 0.0331057456078274 0.9999999983678252 0.1124099045779902 13 P04035,Q15800,Q16850,O75845,P37268,Q9UBM7,Q14534 7 |
| Statin inhibition of cholesterol production 0.7731886478164791 2.1218595471767103 0.0338495343597817 0.999999998972208 0.1136512298895466 6 P35610,P04035,P37268,Q14534 4 |
| Influence of laminopathies on wnt signaling 0.7260269547149809 2.1066850481793473 0.0351448890991921 0.9999999995410946 0.1160553755418376 11 P49354,P49841,O75844,P50402,O60725 5 |
| Oxysterols derived from cholesterol 0.7595785668504309 2.0861499497754608 0.0369650422941629 0.9999999998524725 0.1207390783629997 7 O14975,P22307 2 |
| Fatty acid betaoxidation 0.5818503403075196 2.0583064535571185 0.039560725083406 0.9999999999708648 0.1285188960817676 20 O95573,P55084,P40939,P33121,P49748,P35610,O60488 7 |
| Acquired partial lipodystrophy barraquersimons syndrome 0.7183976095163193 2.003615083176141 0.0451113088748236 0.9999999999991056 0.1383260032335153 5 P49354,O60725,Q03252 3 |
| Mitochondrial immune response to sarscov2 0.7275007839448173 1.990977162958352 0.0464833979813339 0.9999999999996232 0.1418097572933081 9 Q9Y276,Q99623,Q9Y6M9,Q9BQ95,O94826,Q9Y375,Q9H845,P35232 8 |
| Estrogen receptor pathway 0.6308833745217808 1.876598310063963 0.060573169178242 1.0 0.164695664896342 3 Q9HCL2 1 |
| Ketogenesis and ketolysis 0.6597813187842668 1.8529766607177691 0.0638857039788729 1.0 0.1698907437668258 4 P35610 1 |
| Heme biosynthesis 0.6843156508534882 1.8336124591629115 0.0667115414524144 1.0 0.1750813817157251 5 P22830,P50336 2 |
| Glial cell differentiation 0.5863579474342824 1.8101838731585689 0.0702672776384176 1.0 0.1797048249391022 2 P09543 1 |
| Familial partial lipodystrophy fpld 0.6895374500881797 1.7704693371885816 0.0766489880153402 1.0 0.1910046771335968 8 O75844,P49354,O60725,Q03252 4 |
| Mammalian disorder of sexual development 0.5791614518147601 1.7689011685343718 0.0769103691619463 1.0 0.1910046771335968 2 Q14781 1 |
| Extracellular vesiclemediated signaling in recipient cells 0.5791614518147589 1.7689011685343652 0.0769103691619474 1.0 0.1910046771335968 2 P42345 1 |
| 7oxoc and 7betahc pathways 0.6778071190935028 1.7112294822754297 0.0870387582023382 1.0 0.2084075445402599 8 O14975,P22307 2 |
| Progeriaassociated lipodystrophy 0.6584753722877167 1.668965587982946 0.0951241998339089 1.0 0.2182047484739667 10 O75844,P49354,O60725,Q03252 4 |
| Methionine metabolism leading to sulfur amino acids and related disorders 0.6194098762170686 1.6407908781835192 0.1008408324381571 1.0 0.2278396251704226 4 Q99707 1 |
| Copper homeostasis 0.6600082897391002 1.5956688179346847 0.1105627539896445 1.0 0.2413299331069482 7 Q658P3,O75880,Q9Y6N1,P49841 4 |
| Sphingolipid metabolism in senescence 0.5568201015517406 1.540964844674478 0.1233253423151463 1.0 0.2582527203184772 15 Q13510,Q16739,Q96G23,O15269,P04062,Q06136 6 |
| Oligodendrocyte specification and differentiation leading to myelin components for cns 0.5300375469336546 1.4828785832616742 0.1381066725400881 1.0 0.2832503605922373 2 P09543 1 |
| Congenital generalized lipodystrophy cgl 0.5240926157696999 1.4478144700866988 0.1476689447953922 1.0 0.296819517799434 2 P31751 1 |
| Nrf2are regulation 0.6178131842700237 1.381087809922627 0.1672519632193716 1.0 0.3221692140884232 7 P09601 1 |
| Nanoparticle triggered regulated necrosis 0.5040675844805873 1.3291242764879605 0.1838069722420379 1.0 0.3434004785913673 2 Q13546 1 |
| Envelope proteins and their potential roles in edmd physiopathology 0.4914664148856957 1.2449749879489795 0.2131409444041163 1.0 0.3823812166772356 17 P42167,P50402,O94901,Q9BTV4 4 |
| Vitamin d receptor pathway 0.5226266276063823 1.2334755730458529 0.2173983846865019 1.0 0.3877045376753344 14 Q96KA5,Q92604,Q5VV42,P08183 4 |
| Galanin receptor pathway 0.4746558197747123 1.1535954538247324 0.2486660630768868 1.0 0.4242789344480929 2 P14672 1 |
| Pparalpha pathway 0.5627443445127269 1.0970751717616325 0.2726085326769585 1.0 0.4483981210961247 7 P23786,P11802,P22307 3 |
| Tryptophan metabolism 0.492634327554438 1.048879113264629 0.2942337597091735 1.0 0.4682941892787435 14 P35610,P51648,P40939 3 |
| Intracellular trafficking proteins involved in cmt neuropathy 0.5264689071640338 1.0249896343017355 0.3053680786994275 1.0 0.479180718794663 11 P20338,Q8TB36,Q9NR77,P20337,Q9UI14 5 |
| Ccl18 signaling pathway 0.5415697916915212 1.022769227083724 0.3064169710714344 1.0 0.4795744781612814 9 Q86UE4 1 |
| Valproic acid pathway 0.546659668898684 0.9983140273096488 0.3181271077321268 1.0 0.4915022924087615 6 P40939 1 |
| Biomarkers for pyrimidine metabolism disorders 0.5382674058897265 0.9868457533058416 0.3237182610706832 1.0 0.4963129461823485 8 Q9H0P0,Q02127 2 |
| Alzheimers disease and mirna effects 0.3352129112458111 0.98138602078902 0.3264024171457826 1.0 0.4991548414875709 81 Q96IX5,Q9NQC3,P12235,Q9Y277,P12236,P16615,P21796,P05141,O95197,P45880 10 |
| Cysteine and methionine catabolism 0.5371359811725535 0.9644739917755492 0.3348083416631211 1.0 0.5081308417665046 7 Q9Y6N5 1 |
| Hair follicle development cytodifferentiation part 3 of 3 0.4380475594492957 0.934646268114078 0.3499706262375994 1.0 0.5219164922302661 2 P35222 1 |
| Ethanol effects on histone modifications 0.5211375106449374 0.9325629697187178 0.3510456601813039 1.0 0.5220736073247519 10 P04818,P41440,Q99707 3 |
| Acetylcholine synthesis 0.4336670838548075 0.9085387501292412 0.3635936503377581 1.0 0.5329750825682747 2 P08559 1 |
| 15q133 copy number variation syndrome 0.4327284105131251 0.9029494640674774 0.3665527166447266 1.0 0.5335984543608541 2 Q16658 1 |
| Lung fibrosis 0.5258012256387236 0.8920495841058227 0.37236635596126 1.0 0.5375219280182265 6 P09601 1 |
| Cellular proteostasis 0.4550860719874896 0.8878658288716879 0.3746129276506487 1.0 0.5375219280182265 3 Q99471,P61758 2 |
| Ncrnas involved in wnt signaling in hepatocellular carcinoma 0.4935488497294483 0.8414689833247208 0.4000852540053856 1.0 0.5629649359468448 11 Q86UE4 1 |
| Neural crest differentiation 0.5056630093342925 0.8161479560835957 0.414415518663521 1.0 0.5792179691087816 8 Q9NR77 1 |
| Hair follicle development organogenesis part 2 of 3 0.4381846635367862 0.7922430349107847 0.4282189800094236 1.0 0.586240562609712 3 P35222,P05556 2 |
| Sulfation biotransformation reaction 0.4375586854460198 0.7887186881763641 0.4302764427667946 1.0 0.58771850477919 3 P11413,O43252 2 |
| Alzheimers disease 0.3184082909120351 0.7648107693148584 0.4443842340233495 1.0 0.5988227010045584 80 Q9NQC3,P12235,Q9Y277,P12236,P16615,P21796,P05141,O95197,P45880 9 |
| Target of rapamycin tor signaling 0.4945047990644803 0.7581896799057282 0.4483374384751408 1.0 0.60061332721296 8 P04035 1 |
| Sterol regulatory elementbinding proteins srebp signaling 0.3324616195031048 0.7262143162216288 0.4677073969178771 1.0 0.6164301437448336 35 P04035,Q9HCL2,Q9NR31,Q16850,P37268,Q14534,Q9UKV5,Q8WTV0,O00767 9 |
| Pyrimidine metabolism and related diseases 0.4636170127313495 0.6000727356080694 0.5484577619696931 1.0 0.6838653837008 8 Q9H0P0,Q02127 2 |
| Nephrotic syndrome 0.4262844411383046 0.5806167768982549 0.5614987626101859 1.0 0.691517943296561 13 O75844,Q14108,Q9BT22 3 |
| Vitamin b12 metabolism 0.4606867080077708 0.5754529578635729 0.56498499700006 1.0 0.6943885136953702 7 Q8WTV0,P22033 2 |
| Male infertility 0.3574088867810784 0.5007101915948127 0.6165750985976695 1.0 0.7369261215060726 21 Q15165,P41440,P08183 3 |
| Aryl hydrocarbon receptor pathway wp2873 0.4209207641716304 0.4716120156129059 0.6372037486436295 1.0 0.7538571908165774 5 O00170,Q15185,Q16543,P10620 4 |
| Notch signaling 0.4168493579705665 0.4519496045681094 0.6513052879161441 1.0 0.7661793471284893 5 Q13547,Q13363,P56545,Q92769 4 |
| Vitamin dsensitive calcium signaling in depression 0.4291418893238217 0.423308372439244 0.6720702865312675 1.0 0.7790816276890711 7 P20020 1 |
| Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.4253441029582733 0.4055636043021546 0.6850632755582753 1.0 0.7857309706307699 7 P49841 1 |
| Mevalonate arm of cholesterol biosynthesis pathway 0.4072966917151683 0.3414499332136643 0.7327648899347214 1.0 0.8247035559003139 10 P35610,P04035 2 |
| Endothelin pathways 0.4084766277756793 0.3396040231115211 0.7341547480221842 1.0 0.8247233711426779 9 P00403 1 |
| Spinal cord injury 0.339418394867078 0.3250018052673529 0.7451797053958962 1.0 0.8298593941943887 19 P14174,Q9NQC3,Q08722 3 |
| Monoamine transport 0.329161451814759 0.3209980191758118 0.7482118920091643 1.0 0.831192878183933 2 Q16539 1 |
| Pathways of nucleic acid metabolism and innate immune sensing 0.3625547902316788 0.2858240206620418 0.775012909449619 1.0 0.849968537553323 4 P55265,Q7Z434,Q9Y3Z3 3 |
| Nuclear receptors metapathway 0.2835433578124212 0.2673539399650198 0.7891966595724693 1.0 0.8592521601504602 47 P22307,Q9HCL2,O14880,P09601,P08183,Q99735,Q15067,O00767 8 |
| T cell receptor and costimulatory signaling 0.3768048281362549 0.1941692467229517 0.8460433621420052 1.0 0.903147532233295 7 Q15118,P49841 2 |
| Sars coronavirus and innate immunity 0.3205105240489659 0.1898351157350946 0.8494383378328048 1.0 0.9051639025487864 3 P23458 1 |
| Adipogenesis 0.3278605824342475 0.1643605224483037 0.8694473394055406 1.0 0.9232117508528797 16 O75844,O00767 2 |
| Thermogenesis 0.2827136161299908 0.1109391779024514 0.9116645778641804 1.0 0.965973639560765 26 Q15382,P33121,O60488 3 |
| Pdgf pathway 0.317043680111422 0.1093391574118931 0.9129334896347996 1.0 0.965973639560765 16 P53365 1 |
| Angiopoietinlike protein 8 regulatory pathway 0.2738220931236128 0.0820805530152051 0.934582657381305 1.0 0.9871426662322746 29 Q15642,P49841,Q15382,P18031,P41440,O75955,O00767 7 |
| Camkk2 pathway 0.3281992315947637 0.0781295929778267 0.9377249673446342 1.0 0.9887240445160088 13 Q14155,P09601,Q9Y3D6 3 |
| Joubert syndrome 0.2996763898084764 0.0655964041214539 0.9476991520446612 1.0 0.997490701188864 18 Q13432,Q10713 2 |
| Serine metabolism 0.3353180821059229 0.044429812969241 0.9645617977933088 1.0 1.0 7 P04818,O43175,P00374,P78330,P34897,P34896 6 |
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