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- interpro_active_site/advanced/idx2term.json +1 -0
- interpro_active_site/advanced/plot_0.png +3 -0
- interpro_active_site/basic/idx2term.json +1 -0
- interpro_active_site/basic/plot_0.png +3 -0
- interpro_active_site/consensus.joblib +3 -0
- interpro_active_site/df_merge.tsv +2 -0
- interpro_active_site/metrics.json +7 -0
- interpro_active_site/paths.json +1 -0
- interpro_active_site/result.tsv +15 -0
- interpro_active_site/selections.json +1 -0
- interpro_binding_site/advanced/idx2term.json +1 -0
- interpro_binding_site/basic/idx2term.json +1 -0
- interpro_binding_site/basic/plot_0.png +3 -0
- interpro_binding_site/basic/plot_1.png +3 -0
- interpro_binding_site/consensus.joblib +3 -0
- interpro_binding_site/df_merge.tsv +1 -0
- interpro_binding_site/metrics.json +7 -0
- interpro_binding_site/paths.json +1 -0
- interpro_binding_site/result.tsv +7 -0
- interpro_binding_site/selections.json +1 -0
- interpro_conserved_site/advanced/idx2term.json +1 -0
- interpro_conserved_site/basic/idx2term.json +1 -0
- interpro_conserved_site/basic/plot_0.png +3 -0
- interpro_conserved_site/basic/plot_1.png +3 -0
- interpro_conserved_site/basic/plot_2.png +3 -0
- interpro_conserved_site/basic/plot_3.png +3 -0
- interpro_conserved_site/basic/plot_4.png +3 -0
- interpro_conserved_site/basic/plot_5.png +3 -0
- interpro_conserved_site/basic/plot_6.png +3 -0
- interpro_conserved_site/consensus.joblib +3 -0
- interpro_conserved_site/df_merge.tsv +1 -0
- interpro_conserved_site/metrics.json +7 -0
- interpro_conserved_site/paths.json +1 -0
- interpro_conserved_site/result.tsv +53 -0
- interpro_conserved_site/selections.json +1 -0
- interpro_domain/advanced/idx2term.json +1 -0
- interpro_domain/advanced/plot_0.png +3 -0
- interpro_domain/advanced/plot_1.png +3 -0
- interpro_domain/basic/idx2term.json +1 -0
- interpro_domain/basic/plot_0.png +3 -0
- interpro_domain/basic/plot_1.png +3 -0
- interpro_domain/basic/plot_10.png +3 -0
- interpro_domain/basic/plot_11.png +3 -0
- interpro_domain/basic/plot_12.png +3 -0
- interpro_domain/basic/plot_13.png +3 -0
- interpro_domain/basic/plot_14.png +3 -0
- interpro_domain/basic/plot_15.png +3 -0
- interpro_domain/basic/plot_16.png +3 -0
- interpro_domain/basic/plot_17.png +3 -0
- interpro_domain/basic/plot_18.png +3 -0
interpro_active_site/advanced/idx2term.json
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{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}
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interpro_active_site/advanced/plot_0.png
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interpro_active_site/basic/idx2term.json
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{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}
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interpro_active_site/basic/plot_0.png
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Git LFS Details
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interpro_active_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:8b00bcb50c2ce3007775941b9d2c8a391ddeb56e2a244b53e33e1c1e3a335401
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size 80040
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interpro_active_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
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Serine/threonine-protein kinase, active site [IPR008271] 25 59 2.2212092797145764 0.0263367899695459 14.96359223300971 48.092233009708735 -0.2514056606840174 0.5845564538757478 7.386430402173519 10.05983255009733 0.9463339478376924 0.3271131887386243 0.6861003044969223 0.665244999386656 0.6772949914365757 0.2490790055383895
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interpro_active_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3351,
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"annotations_size": 54,
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"title": "Average number of proteins per term",
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"value": 2.962962962962963
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}
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interpro_active_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C096/C096_val_log2fc"}
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interpro_active_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Serine/threonine-protein kinase, active site [IPR008271] 0.4194242602995003 2.2212092797145764 0.0263367899695459 0.7633682233635768 0.1292896962141345 59 Q96KB5,P11802,P45985,O96017,P31751,P68400,P17612,O14965,Q96SB4,Q9NYV4,Q9H2G2,O75116,Q13464,P78362,Q16512,Q16513,Q00534,Q96GX5,Q99986,O43318,P49761,Q15418,Q13131,Q14012,P19784 25
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Ubiquitin-conjugating enzyme, active site [IPR023313] 0.7842970623152395 1.7653421919513168 0.0775062725522388 0.9871759625154648 0.2413668322541955 5 P49427,P68036 2
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Serine carboxypeptidase, serine active site [IPR018202] 0.9664748423805126 1.6272882350627054 0.1036758954151857 0.9972890962362086 0.2799249176210015 3 Q9H3G5 1
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Peptidase family C14A, His active site [IPR016129] 0.766444683584175 1.4644787710161404 0.1430631793208345 0.9997605386586692 0.3358874644923942 4 Q14790 1
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Peptidase family C14A, cysteine active site [IPR033139] 0.766444683584175 1.4644787710161404 0.1430631793208345 0.9997605386586692 0.3358874644923942 4 Q14790 1
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Protein-tyrosine phosphatase, active site [IPR016130] 0.6070085486140906 1.3136229100213717 0.1889731350489703 0.9999877565735836 0.400002870610293 7 O60942,P51452 2
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Nucleoside diphosphate kinase, active site [IPR023005] 0.7823230815168605 0.9923327041625566 0.3210352548170361 0.9999999991687146 0.5592227019393532 2 P15531 1
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Thiolase, acyl-enzyme intermediate active site [IPR020615] 0.5448296473401015 0.7619939509200648 0.4460636144755203 0.999999999999986 0.7039809937872974 5 P55084,P24752,P22307,P09110 4
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ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003] 0.5294739274377123 0.5469386430898279 0.5844208860867486 1.0 0.7795007008280092 4 P38606 1
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Thiolase, active site [IPR020610] 0.4475206238337671 0.4003216946827417 0.6889195909354258 1.0 0.7915246363938935 5 P55084,P24752,P09110 3
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L-lactate dehydrogenase, active site [IPR018177] 0.5264257987459011 0.1906320830680512 0.8488138524636974 1.0 0.9107704672708268 2 P00338 1
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ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440] 0.5198566736339234 0.1783323878995128 0.8584619446015536 1.0 0.9107704672708268 2 P53396 1
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Peptidase S9, serine active site [IPR002471] 0.5186622872499312 0.1761550823573066 0.8601721079780029 1.0 0.9107704672708268 2 P13798 1
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Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.481979363333563 0.1306018835923866 0.8960902526005814 1.0 0.9305552623159884 3 P22314 1
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interpro_active_site/selections.json
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{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP6", "CASP7", "CASP8", "CDC34", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK9", "NME1", "NME2", "OXCT1", "OXSM", "PAK1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCB", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "VRK1", "WNK1", "YES1"], "leading_proteins": ["ACAA1", "ACAT1", "ACLY", "AKT2", "APEH", "ATP6V1A", "AURKA", "CAMK1", "CASP8", "CDC34", "CDK12", "CDK4", "CDK6", "CHEK2", "CLK3", "CPVL", "CSNK2A1", "CSNK2A2", "DUSP3", "HADHB", "LDHA", "MAP2K4", "MAP3K7", "MASTL", "NME1", "PBK", "PKN1", "PKN2", "PRKAA1", "PRKACA", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "SCP2", "SLK", "SRPK1", "SRPK2", "UBA1", "UBE2L3", "VRK1"]}
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interpro_binding_site/advanced/idx2term.json
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{}
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interpro_binding_site/basic/idx2term.json
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{"0": "Protein kinase, ATP binding site [IPR017441]", "1": "Beta tubulin, autoregulation binding site [IPR013838]"}
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interpro_binding_site/basic/plot_0.png
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interpro_binding_site/basic/plot_1.png
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interpro_binding_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:40effbb910ab43d4ed74f14a660d315e53a9f1d8b14185b42cc0c9dfa664ae1d
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size 77552
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interpro_binding_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
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interpro_binding_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3351,
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"annotations_size": 31,
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"title": "Average number of proteins per term",
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"value": 5.032258064516129
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}
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interpro_binding_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C096/C096_val_log2fc"}
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interpro_binding_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Protein kinase, ATP binding site [IPR017441] 0.3843288936624986 1.7563680296876865 0.07902558808264 0.9220754172199216 0.2227084755056219 56 P11802,P45985,P68400,P17612,P31751,O14965,Q9NYV4,Q9H2G2,O75116,Q13464,P78362,Q16512,Q16513,Q00534,Q99986,O43318,P49761,Q15418,Q13131,Q14012,P19784 21
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Beta tubulin, autoregulation binding site [IPR013838] 0.4688916423348493 0.6793952111829175 0.4968874833389101 0.9999999994355588 0.6785686169890758 7 P68371,P04350,P07437,Q9BUF5,Q13885 5
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Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578] 0.6954314720812023 0.6690648120322849 0.5034541351854434 0.9999999996243872 0.6785686169890758 2 Q9Y697 1
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Aconitase family, 4Fe-4S cluster binding site [IPR018136] 0.5768886234696917 0.3029753782659302 0.7619086255468723 1.0 0.9040947455909752 2 P21399 1
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PPM-type phosphatase, divalent cation binding [IPR000222] 0.4215740261143615 0.2273707531429898 0.8201354603602409 1.0 0.9040947455909752 4 O15355,Q5SGD2 2
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Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349] 0.5404598387578388 0.2187383193748735 0.8268538971820814 1.0 0.9040947455909752 2 Q9UQ80 1
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interpro_binding_site/selections.json
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{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "BPNT1", "BUB1", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK4", "CDK5", "CDK6", "CDK9", "CHUK", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "IQSEC1", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP2K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK1", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PPM1L", "PRKAA1", "PRKAA2", "PRKACA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK4", "TBK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["ACO1", "AKT2", "AURKA", "CAMK1", "CDK12", "CDK4", "CDK6", "CLK3", "CSNK2A1", "CSNK2A2", "MAP2K4", "MAP3K7", "NFS1", "PA2G4", "PKN1", "PKN2", "PPM1G", "PPM1L", "PRKAA1", "PRKACA", "ROCK1", "ROCK2", "RPS6KA1", "SLK", "SRPK2", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "VRK1"]}
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interpro_conserved_site/advanced/idx2term.json
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{}
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interpro_conserved_site/basic/idx2term.json
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{"0": "Kinesin motor domain, conserved site [IPR019821]", "1": "ATPase, AAA-type, conserved site [IPR003960]", "2": "Heat shock protein 70, conserved site [IPR018181]", "3": "Tubulin, conserved site [IPR017975]", "4": "Zinc finger, RING-type, conserved site [IPR017907]", "5": "Ubiquitin specific protease, conserved site [IPR018200]", "6": "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]"}
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interpro_conserved_site/basic/plot_0.png
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Git LFS Details
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interpro_conserved_site/basic/plot_1.png
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Git LFS Details
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interpro_conserved_site/basic/plot_2.png
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Git LFS Details
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interpro_conserved_site/basic/plot_3.png
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Git LFS Details
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interpro_conserved_site/basic/plot_4.png
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Git LFS Details
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interpro_conserved_site/basic/plot_5.png
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Git LFS Details
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interpro_conserved_site/basic/plot_6.png
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Git LFS Details
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interpro_conserved_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:8886301930109121a1769d6b0903293b717ddf03c796eff154e90547930f9635
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size 104886
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interpro_conserved_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
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interpro_conserved_site/metrics.json
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{
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"type_of_task": "ranksum",
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+
"signature_size": 3351,
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| 4 |
+
"annotations_size": 279,
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| 5 |
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"title": "Average number of proteins per term",
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| 6 |
+
"value": 2.824372759856631
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+
}
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interpro_conserved_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C096/C096_val_log2fc"}
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interpro_conserved_site/result.tsv
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| 1 |
+
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
|
| 2 |
+
Kinesin motor domain, conserved site [IPR019821] 0.5358625928019357 1.6075369475751835 0.1079366311273095 0.9999999999999856 0.3010152129202317 14 Q9Y496,P52732,Q9BW19,O60333,Q96Q89,Q99661 6
|
| 3 |
+
Chromo domain, conserved site [IPR023779] 0.7398420175316411 1.579738798141987 0.1141666965530419 0.999999999999998 0.3010783425853082 5 Q12873 1
|
| 4 |
+
Rel homology domain, conserved site [IPR030492] 0.8817557479844754 1.383664604069082 0.166461176547692 1.0 0.3935819343797124 2 Q00653 1
|
| 5 |
+
Adenylate kinase, conserved site [IPR033690] 0.7077044726775961 1.2296229411687527 0.2188383351314498 1.0 0.492386254045762 4 P30085 1
|
| 6 |
+
Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331] 0.8460732866053197 1.1875760410973673 0.2350004817177071 1.0 0.5049251074088014 3 Q6XZF7 1
|
| 7 |
+
HMG box A DNA-binding domain, conserved site [IPR017967] 0.8410991636798062 1.1694825089924876 0.242209284288088 1.0 0.5049251074088014 3 P09429,P26583 2
|
| 8 |
+
FERM conserved site [IPR019747] 0.5164526029118405 1.1693403485330836 0.2422665329069948 1.0 0.5049251074088014 10 Q9Y490,P26038,Q9HCM4,P35241 4
|
| 9 |
+
F-actin capping protein, alpha subunit, conserved site [IPR017865] 0.8271125709166951 1.1672010170363232 0.2431292002899985 1.0 0.5049251074088014 2 P47755 1
|
| 10 |
+
Ubiquitin interacting motif [IPR003903] 0.83721624850657 1.1553719701964518 0.2479381351792322 1.0 0.5049251074088014 3 P55036,P42566 2
|
| 11 |
+
Cullin, conserved site [IPR016157] 0.5801331069486846 1.0922746873416156 0.274712382826709 1.0 0.5397517944271255 6 Q13618,Q13620,Q13619 3
|
| 12 |
+
Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770] 0.7996416840847782 1.059532204421034 0.2893574706700643 1.0 0.552430614869815 2 O60573 1
|
| 13 |
+
ATPase, AAA-type, conserved site [IPR003960] 0.3918261182581155 1.0578999523861543 0.2901010569093749 1.0 0.552430614869815 22 Q6PL18,Q9UN37,P62195,P17980,Q8NB90,Q9BVQ7,P35998,P43686,P62191,P62333 10
|
| 14 |
+
Serpin, conserved site [IPR023795] 0.7975515079128085 1.0513901086118225 0.2930794568795445 1.0 0.5524943815499521 2 P50454 1
|
| 15 |
+
Heat shock protein 70, conserved site [IPR018181] 0.4738168966202301 0.944043825416888 0.3451472533615365 1.0 0.6252992447264201 10 Q92598,P54652,O95757,P0DMV9,P11142,Q9Y4L1,Q0VDF9 7
|
| 16 |
+
Thiosulphate sulfurtransferase, conserved site [IPR001307] 0.7653030755449344 0.9269639148681194 0.3539452701889118 1.0 0.6325498999159154 2 Q16762 1
|
| 17 |
+
Fork head domain conserved site1 [IPR018122] 0.76905345040081 0.9107822145419892 0.3624101353680815 1.0 0.6325498999159154 3 P85037 1
|
| 18 |
+
Fork head domain conserved site 2 [IPR030456] 0.76905345040081 0.9107822145419892 0.3624101353680815 1.0 0.6325498999159154 3 P85037 1
|
| 19 |
+
tRNA-dihydrouridine synthase, conserved site [IPR018517] 0.739922364885039 0.8310510402249819 0.4059447963455431 1.0 0.6691411562649593 2 Q9NX74 1
|
| 20 |
+
AT hook, DNA-binding motif [IPR017956] 0.7357563929908051 0.7947555099906399 0.4267557353240345 1.0 0.6848527917210206 3 P17096 1
|
| 21 |
+
Fructose-bisphosphate aldolase class-I active site [IPR029768] 0.7282770976410919 0.787804816426595 0.4308108833618711 1.0 0.6848527917210206 2 P09972 1
|
| 22 |
+
Mrp, conserved site [IPR000808] 0.7145039896441563 0.7225202760127386 0.4699746639462638 1.0 0.712624626309824 3 Q9Y5Y2 1
|
| 23 |
+
Tubulin, conserved site [IPR017975] 0.4688916423348493 0.6793952111829175 0.4968874833389101 1.0 0.7279924080928795 7 P68371,P04350,P07437,Q9BUF5,Q13885 5
|
| 24 |
+
Chaperonin TCP-1, conserved site [IPR002194] 0.4500768206411824 0.6704930758315106 0.5025435189584888 1.0 0.7279924080928795 8 P48643,P40227 2
|
| 25 |
+
Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.6721409375933108 0.5884019526557935 0.5562625274067112 1.0 0.7703350682338785 2 P06737 1
|
| 26 |
+
Acyl-CoA-binding protein, ACBP, conserved site [IPR022408] 0.6700507614213214 0.5813303022022078 0.5610178616200008 1.0 0.7703350682338785 2 Q9H3P7 1
|
| 27 |
+
Thiolase, conserved site [IPR020613] 0.4603168444248701 0.5755375308517074 0.5649278157421684 1.0 0.7703350682338785 6 P55084,P24752,P22307,P09110 4
|
| 28 |
+
Zinc finger, PHD-type, conserved site [IPR019786] 0.3327289007395607 0.5727043430317575 0.5668448963533381 1.0 0.7703350682338785 18 P29375,O75151,Q12873 3
|
| 29 |
+
Zinc finger, RING-type, conserved site [IPR017907] 0.3230086241313134 0.5623122669230978 0.5739032819885781 1.0 0.7703350682338785 19 Q8NCN4,P38398,P22681,O95376,Q9H000 5
|
| 30 |
+
Phosphofructokinase, conserved site [IPR015912] 0.6478494623655826 0.509225480944415 0.6105941843926883 1.0 0.792352453235163 3 Q01813,P08237 2
|
| 31 |
+
Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.62066905615292 0.4299516799536743 0.6672307908721025 1.0 0.8273661806814071 3 Q16539,P28482 2
|
| 32 |
+
Ubiquitin specific protease, conserved site [IPR018200] 0.3175147838583426 0.4250856018694824 0.6707742735046149 1.0 0.8280797447247238 16 P51784,P40818,Q96RU2,P45974,O94966,Q14694,Q70CQ2,P54578,Q8TEY7 9
|
| 33 |
+
Actin, conserved site [IPR004001] 0.6106300388175614 0.394419116332005 0.6932716325399064 1.0 0.8517386292806002 2 O96019 1
|
| 34 |
+
Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.5957002090176171 0.3524723584917997 0.7244840447771983 1.0 0.8748487806473293 2 P29692 1
|
| 35 |
+
GTP1/OBG, conserved site [IPR006074] 0.5870409077336459 0.3292074230324159 0.7419989126095567 1.0 0.8884879683178812 2 Q9Y295 1
|
| 36 |
+
Ubiquitin-activating enzyme E1, conserved site [IPR018074] 0.5789787996416867 0.3082819357537468 0.7578678103085541 1.0 0.89976646415356 2 P22314 1
|
| 37 |
+
Dynamin, GTPase region, conserved site [IPR019762] 0.5700209017617207 0.2858904302564431 0.7749620435367719 1.0 0.9046628039613362 2 P50570 1
|
| 38 |
+
Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866] 0.5555555555555441 0.2649417501824655 0.7910543351984374 1.0 0.9139251044478106 3 P53396,Q96I99 2
|
| 39 |
+
Mini-chromosome maintenance, conserved site [IPR018525] 0.3706879510659952 0.2599495969455077 0.7949026530909642 1.0 0.9139251044478106 6 P33993,P33991 2
|
| 40 |
+
Heat shock protein Hsp90, conserved site [IPR019805] 0.5469937378291 0.2462791525563331 0.8054661468794695 1.0 0.9210043236859508 3 P07900 1
|
| 41 |
+
DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.5491191400418092 0.2373090940008234 0.8124170075940658 1.0 0.9231281600883334 2 P28340 1
|
| 42 |
+
Profilin conserved site [IPR027310] 0.5482233502538127 0.2353450160634475 0.8139409583574553 1.0 0.9231281600883334 2 P35080 1
|
| 43 |
+
ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629] 0.2395474767562706 0.2166520234252115 0.8284795396483753 1.0 0.9339087790512876 21 Q9UHI6,Q14240,P26196 3
|
| 44 |
+
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.4159977858254008 0.2145205582523695 0.8301411369344778 1.0 0.9339087790512876 4 Q13363 1
|
| 45 |
+
DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.2613607672178951 0.2067359305702032 0.8362160949902546 1.0 0.9369650220975142 16 O60231,Q86WJ1,Q12873 3
|
| 46 |
+
Polyprenyl synthetase, conserved site [IPR033749] 0.5258286055539036 0.1894912651138467 0.8497078005128356 1.0 0.9405482630781328 2 P14324 1
|
| 47 |
+
ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847] 0.5198566736339234 0.1783323878995128 0.8584619446015536 1.0 0.9429562304875332 2 P53396 1
|
| 48 |
+
Cadherin conserved site [IPR020894] 0.3848222288616794 0.1506416947388773 0.8802583690363361 1.0 0.9519073060509216 4 Q14574,Q02487,Q14126 3
|
| 49 |
+
Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314] 0.4953717527620265 0.1373284079736099 0.8907712168375164 1.0 0.9519892594415276 2 Q8TEA1 1
|
| 50 |
+
Fumarate lyase, conserved site [IPR020557] 0.4935801731860336 0.1346266338028935 0.8929070825773002 1.0 0.9519892594415276 2 P07954 1
|
| 51 |
+
Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412] 0.2357975251486651 0.1169075860157062 0.9069332866082414 1.0 0.9519892594415276 14 Q9Y2Z4,P07814,Q5ST30,P47897,Q9P2J5,P56192,P26640,P41252 8
|
| 52 |
+
Alpha-D-phosphohexomutase, conserved site [IPR016066] 0.368912636264337 0.0342836317394516 0.9726509771767576 1.0 0.9980740924649638 3 O95394 1
|
| 53 |
+
3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.3538884680286322 0.0291846923352434 0.9767172897810876 1.0 0.9981836038422104 3 Q16836 1
|
interpro_conserved_site/selections.json
ADDED
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{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Carbonic anhydrase, alpha-class, conserved site [IPR018338]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF2", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "APEX1", "ARHGEF7", "ARIH2", "ARRB1", "ARSA", "ATAD1", "ATAD2", "ATAD2B", "ATM", "ATP5C1", "ATP5O", "ATR", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CA8", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX3", "CBX4", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD320", "CDC40", "CDH2", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CIAO1", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1A", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMBP", "DNMT1", "DRG1", "DRG2", "DSC2", "DSC3", "DSG2", "DST", "DTYMK", "DUS1L", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FOXK2", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPR2", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HOXA10", "HOXD11", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPACT", "IMPDH1", "IMPDH2", "IQGAP1", "IQGAP2", "ISCA2", "IVD", "KATNA1", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LIG4", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPI", "MPP1", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFM", "NES", "NF1", "NFKB2", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NSUN6", "NUBP1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF2", "PHF3", "PHF8", "PHGDH", "PHIP", "PHRF1", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RNF169", "RNF2", "RNF20", "RNF31", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SFN", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE4", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP22", "USP24", "USP28", "USP33", "USP34", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR47", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ACAA1", "ACAT1", "ACBD3", "ACLY", "ACTL6A", "ALDOC", "ARIH2", "ATAD2", "BRCA1", "CAPZA2", "CBL", "CCT5", "CCT6A", "CHD1L", "CHD3", "CMPK1", "CTBP1", "CUL3", "CUL4A", "CUL4B", "DDX20", "DDX6", "DHX16", "DNM2", "DNMBP", "DRG1", "DSC2", "DSC3", "DSG2", "DUS2", "EEF1D", "EIF4A2", "EIF4E2", "EPB41L5", "EPRS", "EPS15", "FDPS", "FH", "FOXK1", "HADH", "HADHB", "HMGA1", "HMGB1", "HMGB2", "HSP90AA1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPH1", "HYOU1", "IARS", "KDM5A", "KIF11", "KIF1B", "KIF20B", "KIF2C", "KIF3A", "KIFC1", "LARS", "MAPK1", "MAPK14", "MARS", "MCM4", "MCM7", "MKRN2", "MSN", "NFKB2", "NSUN6", "NUBP2", "PFKM", "PFKP", "PFN2", "PGM3", "PHF2", "POLD1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PYGL", "QARS", "RDX", "RNF169", "SCP2", "SERPINH1", "SPATA5", "SPATA5L1", "SUCLG2", "TLN1", "TST", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "UBA1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP34", "USP5", "USP8", "VARS1", "VARS2", "VPS4A", "YARS2"]}
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{"0": "SH3 domain [IPR001452]", "1": "Ubiquitin-like domain [IPR000626]"}
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{"0": "SH3 domain [IPR001452]", "1": "Ubiquitin-like domain [IPR000626]", "2": "Protein kinase domain [IPR000719]", "3": "PDZ domain [IPR001478]", "4": "Pleckstrin homology domain [IPR001849]", "5": "Phox homology [IPR001683]", "6": "SH2 domain [IPR000980]", "7": "Kinesin motor domain [IPR001752]", "8": "Cullin, N-terminal [IPR001373]", "9": "High mobility group box domain [IPR009071]", "10": "AGC-kinase, C-terminal [IPR000961]", "11": "Ubiquitin-associated domain [IPR015940]", "12": "WW domain [IPR001202]", "13": "Zinc finger C2H2-type [IPR013087]", "14": "THIF-type NAD/FAD binding fold [IPR000594]", "15": "AAA ATPase, AAA+ lid domain [IPR041569]", "16": "FERM central domain [IPR019748]", "17": "Band 4.1 domain [IPR019749]", "18": "Zinc finger, CCCH-type [IPR000571]", "19": "Tubulin/FtsZ, GTPase domain [IPR003008]", "20": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "21": "ATPase, AAA-type, core [IPR003959]", "22": "Proteasome component (PCI) domain [IPR000717]", "23": "AAA+ ATPase domain [IPR003593]", "24": "Ubiquitin specific protease domain [IPR028889]", "25": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "26": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "27": "Aminoacyl-tRNA synthetase, class II [IPR006195]", "28": "K Homology domain, type 1 [IPR004088]", "29": "Zinc finger, PHD-finger [IPR019787]", "30": "K Homology domain [IPR004087]", "31": "Calponin homology domain [IPR001715]", "32": "Zinc finger, PHD-type [IPR001965]", "33": "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "34": "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "35": "Helicase, C-terminal [IPR001650]", "36": "CBS domain [IPR000644]", "37": "Glutathione S-transferase, C-terminal [IPR004046]"}
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